Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:51317
• Symbol:PHF21A
• Description:PHD finger protein 21A

DataSource: http://genomecrispr.dkfz.de/#!/results/PHF21A

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
46084195	46084218	11	-	26472758	Jiyoye	viability	GGAGTTGCAGACTCTACAGGAGG	PHF21A	ENSG00000135365	-0.06829797163494455	[259]	[186]	0	hSpCas9	negative selection	119854
45948900	45948923	11	-	26472758	Jiyoye	viability	CTAAACAGCACAATGCACCCTGG	PHF21A	ENSG00000135365	-0.10577587429989466	[126]	[88]	0	hSpCas9	negative selection	119855
45971266	45971289	11	+	26472758	Jiyoye	viability	AGGTCTCTGGCCCACCACAGAGG	PHF21A	ENSG00000135365	0.05353842689117305	[91]	[71]	0	hSpCas9	negative selection	119856
45971242	45971265	11	+	26472758	Jiyoye	viability	GATGGCGGTCACCATAGCAATGG	PHF21A	ENSG00000135365	2.5087134079679356	[23]	[102]	9	hSpCas9	negative selection	119857
45965538	45965561	11	+	26472758	Jiyoye	viability	GGAGCTGCGAGCATGGGAGGTGG	PHF21A	ENSG00000135365	-1.9553946978788348	[143]	[27]	-8	hSpCas9	negative selection	119858
45965443	45965466	11	+	26472758	Jiyoye	viability	CATTGACGACACGGACGGGGTGG	PHF21A	ENSG00000135365	1.0990530861435412	[12]	[20]	7	hSpCas9	negative selection	119859
45979780	45979803	11	+	26472758	Jiyoye	viability	GAGAGGCTGCAGCTGACTGCTGG	PHF21A	ENSG00000135365	0.8222128807847173	[53]	[71]	6	hSpCas9	negative selection	119860
45965522	45965545	11	-	26472758	Jiyoye	viability	CAGCTCCTCAGCTTATCCAGAGG	PHF21A	ENSG00000135365	1.6551028949494588	[7]	[18]	8	hSpCas9	negative selection	119861
45965390	45965413	11	+	26472758	Jiyoye	viability	AATGCTGGTGAGCTGGGCCATGG	PHF21A	ENSG00000135365	0.0023336493329181307	[93]	[70]	0	hSpCas9	negative selection	119862
45953538	45953561	11	-	26472758	Jiyoye	viability	TGCACCCAAACCAAAACGGGAGG	PHF21A	ENSG00000135365	0.352727597483497	[80]	[77]	2	hSpCas9	negative selection	119863
46084195	46084218	11	-	26472758	KBM7	viability	GGAGTTGCAGACTCTACAGGAGG	PHF21A	ENSG00000135365	0.4284858333767333	[581,551]	[414,309]	4	hSpCas9	negative selection	310972
45948900	45948923	11	-	26472758	KBM7	viability	CTAAACAGCACAATGCACCCTGG	PHF21A	ENSG00000135365	0.5165083304657292	[678,524]	[503,309]	5	hSpCas9	negative selection	310973
45971266	45971289	11	+	26472758	KBM7	viability	AGGTCTCTGGCCCACCACAGAGG	PHF21A	ENSG00000135365	0.786092804137253	[254,257]	[310,117]	8	hSpCas9	negative selection	310974
45971242	45971265	11	+	26472758	KBM7	viability	GATGGCGGTCACCATAGCAATGG	PHF21A	ENSG00000135365	0.23256086733457887	[371,302]	[224,149]	2	hSpCas9	negative selection	310975
45965538	45965561	11	+	26472758	KBM7	viability	GGAGCTGCGAGCATGGGAGGTGG	PHF21A	ENSG00000135365	-0.6619387621206665	[297,165]	[80,54]	-5	hSpCas9	negative selection	310976
45965443	45965466	11	+	26472758	KBM7	viability	CATTGACGACACGGACGGGGTGG	PHF21A	ENSG00000135365	-0.00516864652965543	[222,110]	[95,57]	0	hSpCas9	negative selection	310977
45979780	45979803	11	+	26472758	KBM7	viability	GAGAGGCTGCAGCTGACTGCTGG	PHF21A	ENSG00000135365	0.2621757935286639	[370,426]	[289,171]	2	hSpCas9	negative selection	310978
45965522	45965545	11	-	26472758	KBM7	viability	CAGCTCCTCAGCTTATCCAGAGG	PHF21A	ENSG00000135365	-0.14232341232719015	[239,159]	[123,47]	-1	hSpCas9	negative selection	310979
45965390	45965413	11	+	26472758	KBM7	viability	AATGCTGGTGAGCTGGGCCATGG	PHF21A	ENSG00000135365	0.30946819369587114	[476,320]	[153,295]	3	hSpCas9	negative selection	310980
45953538	45953561	11	-	26472758	KBM7	viability	TGCACCCAAACCAAAACGGGAGG	PHF21A	ENSG00000135365	0.7401944723338194	[262,197]	[182,175]	7	hSpCas9	negative selection	310981
46084195	46084218	11	-	26472758	Raji	viability	GGAGTTGCAGACTCTACAGGAGG	PHF21A	ENSG00000135365	0.13614252835502344	[297]	[75]	1	hSpCas9	negative selection	502090
45948900	45948923	11	-	26472758	Raji	viability	CTAAACAGCACAATGCACCCTGG	PHF21A	ENSG00000135365	-0.05052894836673294	[298]	[66]	0	hSpCas9	negative selection	502091
45971266	45971289	11	+	26472758	Raji	viability	AGGTCTCTGGCCCACCACAGAGG	PHF21A	ENSG00000135365	0.3308895770207559	[184]	[53]	3	hSpCas9	negative selection	502092
45971242	45971265	11	+	26472758	Raji	viability	GATGGCGGTCACCATAGCAATGG	PHF21A	ENSG00000135365	0.3911765013741906	[160]	[48]	4	hSpCas9	negative selection	502093
45965538	45965561	11	+	26472758	Raji	viability	GGAGCTGCGAGCATGGGAGGTGG	PHF21A	ENSG00000135365	-1.127832926320432	[112]	[11]	-7	hSpCas9	negative selection	502094
45965443	45965466	11	+	26472758	Raji	viability	CATTGACGACACGGACGGGGTGG	PHF21A	ENSG00000135365	0.42931163026096186	[79]	[24]	4	hSpCas9	negative selection	502095
45979780	45979803	11	+	26472758	Raji	viability	GAGAGGCTGCAGCTGACTGCTGG	PHF21A	ENSG00000135365	0.48906243770601243	[174]	[56]	4	hSpCas9	negative selection	502096
45965522	45965545	11	-	26472758	Raji	viability	CAGCTCCTCAGCTTATCCAGAGG	PHF21A	ENSG00000135365	0.6619723870512368	[127]	[46]	6	hSpCas9	negative selection	502097
45965390	45965413	11	+	26472758	Raji	viability	AATGCTGGTGAGCTGGGCCATGG	PHF21A	ENSG00000135365	-0.4589632871802096	[230]	[38]	-4	hSpCas9	negative selection	502098
45953538	45953561	11	-	26472758	Raji	viability	TGCACCCAAACCAAAACGGGAGG	PHF21A	ENSG00000135365	-1.365104236089144	[110]	[9]	-7	hSpCas9	negative selection	502099
46084195	46084218	11	-	26472758	K562	viability	GGAGTTGCAGACTCTACAGGAGG	PHF21A	ENSG00000135365	0.6869921766336697	[492]	[669]	5	hSpCas9	negative selection	693208
45948900	45948923	11	-	26472758	K562	viability	CTAAACAGCACAATGCACCCTGG	PHF21A	ENSG00000135365	-0.33098946634146065	[300]	[201]	-2	hSpCas9	negative selection	693209
45971266	45971289	11	+	26472758	K562	viability	AGGTCTCTGGCCCACCACAGAGG	PHF21A	ENSG00000135365	-0.5823304451844636	[336]	[189]	-4	hSpCas9	negative selection	693210
45971242	45971265	11	+	26472758	K562	viability	GATGGCGGTCACCATAGCAATGG	PHF21A	ENSG00000135365	0.6610442238484828	[226]	[302]	5	hSpCas9	negative selection	693211
45965538	45965561	11	+	26472758	K562	viability	GGAGCTGCGAGCATGGGAGGTGG	PHF21A	ENSG00000135365	-4.366078865161846	[170]	[6]	-9	hSpCas9	negative selection	693212
45965443	45965466	11	+	26472758	K562	viability	CATTGACGACACGGACGGGGTGG	PHF21A	ENSG00000135365	0.5492733091948676	[118]	[146]	4	hSpCas9	negative selection	693213
45979780	45979803	11	+	26472758	K562	viability	GAGAGGCTGCAGCTGACTGCTGG	PHF21A	ENSG00000135365	-0.0256704357012974	[327]	[271]	0	hSpCas9	negative selection	693214
45965522	45965545	11	-	26472758	K562	viability	CAGCTCCTCAGCTTATCCAGAGG	PHF21A	ENSG00000135365	-0.9296106721086022	[175]	[77]	-5	hSpCas9	negative selection	693215
45965390	45965413	11	+	26472758	K562	viability	AATGCTGGTGAGCTGGGCCATGG	PHF21A	ENSG00000135365	0.1267236849966924	[216]	[199]	0	hSpCas9	negative selection	693216
45953538	45953561	11	-	26472758	K562	viability	TGCACCCAAACCAAAACGGGAGG	PHF21A	ENSG00000135365	0.17883038603887036	[179]	[171]	1	hSpCas9	negative selection	693217
45965383	45965406	11	+	26627737	DLD1	viability	CTATCACAATGCTGGTGAGCTGG	PHF21A	ENSG00000135365	0.4916016057092031	[484]	[229,301,124]	5	hSpCas9	negative selection	778587
45969816	45969839	11	+	26627737	DLD1	viability	TGTGGAAGAAAGTTTGGACGTGG	PHF21A	ENSG00000135365	0.2530637639251918	[778]	[184,315,359]	2	hSpCas9	negative selection	778588
45971242	45971265	11	+	26627737	DLD1	viability	GATGGCGGTCACCATAGCAATGG	PHF21A	ENSG00000135365	0.7774230529466941	[257]	[181,105,126]	7	hSpCas9	negative selection	778589
46049431	46049454	11	+	26627737	DLD1	viability	CACAGTGTATTCCTGTACAGTGG	PHF21A	ENSG00000135365	-0.028359471699891392	[1186]	[264,460,368]	0	hSpCas9	negative selection	778590
46079142	46079165	11	-	26627737	DLD1	viability	ACTGGTTGCTCAAATGAAGCAGG	PHF21A	ENSG00000135365	0.9774127989096857	[253]	[156,120,184]	8	hSpCas9	negative selection	778591
46084195	46084218	11	-	26627737	DLD1	viability	GGAGTTGCAGACTCTACAGGAGG	PHF21A	ENSG00000135365	0.6856839777825339	[299]	[194,101,152]	6	hSpCas9	negative selection	778592
45965383	45965406	11	+	26627737	GBM cells	viability after 5 days	CTATCACAATGCTGGTGAGCTGG	PHF21A	ENSG00000135365	0.6226491591993728	[240]	[184,212]	8	hSpCas9	negative selection	860902
45969816	45969839	11	+	26627737	GBM cells	viability after 5 days	TGTGGAAGAAAGTTTGGACGTGG	PHF21A	ENSG00000135365	-0.646436769936614	[466]	[167,151]	-8	hSpCas9	negative selection	860903
45971242	45971265	11	+	26627737	GBM cells	viability after 5 days	GATGGCGGTCACCATAGCAATGG	PHF21A	ENSG00000135365	-0.6552863720647837	[115]	[28,49]	-8	hSpCas9	negative selection	860904
46049431	46049454	11	+	26627737	GBM cells	viability after 5 days	CACAGTGTATTCCTGTACAGTGG	PHF21A	ENSG00000135365	-0.40567594337517454	[640]	[289,228]	-6	hSpCas9	negative selection	860905
46079142	46079165	11	-	26627737	GBM cells	viability after 5 days	ACTGGTTGCTCAAATGAAGCAGG	PHF21A	ENSG00000135365	0.41348704771544387	[209]	[128,170]	6	hSpCas9	negative selection	860906
46084195	46084218	11	-	26627737	GBM cells	viability after 5 days	GGAGTTGCAGACTCTACAGGAGG	PHF21A	ENSG00000135365	-0.4943192540748099	[196]	[67,81]	-7	hSpCas9	negative selection	860907
45965383	45965406	11	+	26627737	GBM cells	viability after 13 days	CTATCACAATGCTGGTGAGCTGG	PHF21A	ENSG00000135365	0.7589871423868374	[240]	[244,201]	8	hSpCas9	negative selection	943217
45969816	45969839	11	+	26627737	GBM cells	viability after 13 days	TGTGGAAGAAAGTTTGGACGTGG	PHF21A	ENSG00000135365	-0.618274896882303	[466]	[158,169]	-6	hSpCas9	negative selection	943218
45971242	45971265	11	+	26627737	GBM cells	viability after 13 days	GATGGCGGTCACCATAGCAATGG	PHF21A	ENSG00000135365	-0.2162833667081283	[115]	[62,46]	-3	hSpCas9	negative selection	943219
46049431	46049454	11	+	26627737	GBM cells	viability after 13 days	CACAGTGTATTCCTGTACAGTGG	PHF21A	ENSG00000135365	-0.31033392199200827	[640]	[419,166]	-4	hSpCas9	negative selection	943220
46079142	46079165	11	-	26627737	GBM cells	viability after 13 days	ACTGGTTGCTCAAATGAAGCAGG	PHF21A	ENSG00000135365	0.5407866649177206	[209]	[162,167]	6	hSpCas9	negative selection	943221
46084195	46084218	11	-	26627737	GBM cells	viability after 13 days	GGAGTTGCAGACTCTACAGGAGG	PHF21A	ENSG00000135365	-1.1683075736546065	[196]	[62,34]	-8	hSpCas9	negative selection	943222
45965383	45965406	11	+	26627737	GBM cells	viability after 21 days	CTATCACAATGCTGGTGAGCTGG	PHF21A	ENSG00000135365	0.08027572414244236	[240]	[151,125]	0	hSpCas9	negative selection	1025532
45969816	45969839	11	+	26627737	GBM cells	viability after 21 days	TGTGGAAGAAAGTTTGGACGTGG	PHF21A	ENSG00000135365	-1.3066273073689771	[466]	[100,103]	-8	hSpCas9	negative selection	1025533
45971242	45971265	11	+	26627737	GBM cells	viability after 21 days	GATGGCGGTCACCATAGCAATGG	PHF21A	ENSG00000135365	-0.18390960051149574	[115]	[55,54]	-2	hSpCas9	negative selection	1025534
46049431	46049454	11	+	26627737	GBM cells	viability after 21 days	CACAGTGTATTCCTGTACAGTGG	PHF21A	ENSG00000135365	-0.3625673747994893	[640]	[285,256]	-3	hSpCas9	negative selection	1025535
46079142	46079165	11	-	26627737	GBM cells	viability after 21 days	ACTGGTTGCTCAAATGAAGCAGG	PHF21A	ENSG00000135365	0.3926675616890817	[209]	[154,144]	4	hSpCas9	negative selection	1025536
46084195	46084218	11	-	26627737	GBM cells	viability after 21 days	GGAGTTGCAGACTCTACAGGAGG	PHF21A	ENSG00000135365	-2.834927924232199	[196]	[14,14]	-9	hSpCas9	negative selection	1025537
45965383	45965406	11	+	26627737	RPE1	viability after 9 days	CTATCACAATGCTGGTGAGCTGG	PHF21A	ENSG00000135365	0.4366957354538495	[923]	[222,608]	3	hSpCas9	negative selection	1107847
45969816	45969839	11	+	26627737	RPE1	viability after 9 days	TGTGGAAGAAAGTTTGGACGTGG	PHF21A	ENSG00000135365	-0.6096026576325533	[1632]	[238,458]	-4	hSpCas9	negative selection	1107848
45971242	45971265	11	+	26627737	RPE1	viability after 9 days	GATGGCGGTCACCATAGCAATGG	PHF21A	ENSG00000135365	1.6000467522702193	[168]	[107,227]	8	hSpCas9	negative selection	1107849
46049431	46049454	11	+	26627737	RPE1	viability after 9 days	CACAGTGTATTCCTGTACAGTGG	PHF21A	ENSG00000135365	1.3100726368329891	[1112]	[887,832]	7	hSpCas9	negative selection	1107850
46079142	46079165	11	-	26627737	RPE1	viability after 9 days	ACTGGTTGCTCAAATGAAGCAGG	PHF21A	ENSG00000135365	-0.1258599283996668	[584]	[152,186]	-1	hSpCas9	negative selection	1107851
46084195	46084218	11	-	26627737	RPE1	viability after 9 days	GGAGTTGCAGACTCTACAGGAGG	PHF21A	ENSG00000135365	-0.7585736800074274	[685]	[67,202]	-5	hSpCas9	negative selection	1107852
45965383	45965406	11	+	26627737	RPE1	viability after 12 days	CTATCACAATGCTGGTGAGCTGG	PHF21A	ENSG00000135365	0.23178514474111211	[923]	[274,308]	1	hSpCas9	negative selection	1190162
45969816	45969839	11	+	26627737	RPE1	viability after 12 days	TGTGGAAGAAAGTTTGGACGTGG	PHF21A	ENSG00000135365	-0.4660007820223051	[1632]	[372,258]	-3	hSpCas9	negative selection	1190163
45971242	45971265	11	+	26627737	RPE1	viability after 12 days	GATGGCGGTCACCATAGCAATGG	PHF21A	ENSG00000135365	1.9291452306627246	[168]	[118,229]	8	hSpCas9	negative selection	1190164
46049431	46049454	11	+	26627737	RPE1	viability after 12 days	CACAGTGTATTCCTGTACAGTGG	PHF21A	ENSG00000135365	1.0029049243143329	[1112]	[607,589]	6	hSpCas9	negative selection	1190165
46079142	46079165	11	-	26627737	RPE1	viability after 12 days	ACTGGTTGCTCAAATGAAGCAGG	PHF21A	ENSG00000135365	-0.8675221329551484	[584]	[107,62]	-5	hSpCas9	negative selection	1190166
46084195	46084218	11	-	26627737	RPE1	viability after 12 days	GGAGTTGCAGACTCTACAGGAGG	PHF21A	ENSG00000135365	-0.6262943281222317	[685]	[64,176]	-4	hSpCas9	negative selection	1190167
45965383	45965406	11	+	26627737	RPE1	viability after 15 days	CTATCACAATGCTGGTGAGCTGG	PHF21A	ENSG00000135365	0.29081569329341644	[923]	[417,224]	2	hSpCas9	negative selection	1272477
45969816	45969839	11	+	26627737	RPE1	viability after 15 days	TGTGGAAGAAAGTTTGGACGTGG	PHF21A	ENSG00000135365	-0.6528096251442241	[1632]	[219,364]	-4	hSpCas9	negative selection	1272478
45971242	45971265	11	+	26627737	RPE1	viability after 15 days	GATGGCGGTCACCATAGCAATGG	PHF21A	ENSG00000135365	1.7991888163279652	[168]	[116,213]	8	hSpCas9	negative selection	1272479
46049431	46049454	11	+	26627737	RPE1	viability after 15 days	CACAGTGTATTCCTGTACAGTGG	PHF21A	ENSG00000135365	1.362511162286734	[1112]	[1030,595]	7	hSpCas9	negative selection	1272480
46079142	46079165	11	-	26627737	RPE1	viability after 15 days	ACTGGTTGCTCAAATGAAGCAGG	PHF21A	ENSG00000135365	-0.5435928995808579	[584]	[167,60]	-3	hSpCas9	negative selection	1272481
46084195	46084218	11	-	26627737	RPE1	viability after 15 days	GGAGTTGCAGACTCTACAGGAGG	PHF21A	ENSG00000135365	-0.9024834645256286	[685]	[29,174]	-5	hSpCas9	negative selection	1272482
45965383	45965406	11	+	26627737	RPE1	viability after 18 days	CTATCACAATGCTGGTGAGCTGG	PHF21A	ENSG00000135365	0.15749962040679416	[923]	[135,429]	1	hSpCas9	negative selection	1354792
45969816	45969839	11	+	26627737	RPE1	viability after 18 days	TGTGGAAGAAAGTTTGGACGTGG	PHF21A	ENSG00000135365	-0.535510892679825	[1632]	[246,364]	-3	hSpCas9	negative selection	1354793
45971242	45971265	11	+	26627737	RPE1	viability after 18 days	GATGGCGGTCACCATAGCAATGG	PHF21A	ENSG00000135365	2.4698352588665564	[168]	[198,309]	9	hSpCas9	negative selection	1354794
46049431	46049454	11	+	26627737	RPE1	viability after 18 days	CACAGTGTATTCCTGTACAGTGG	PHF21A	ENSG00000135365	1.1871629379688216	[1112]	[725,638]	6	hSpCas9	negative selection	1354795
46079142	46079165	11	-	26627737	RPE1	viability after 18 days	ACTGGTTGCTCAAATGAAGCAGG	PHF21A	ENSG00000135365	0.28500634322194895	[584]	[260,118]	1	hSpCas9	negative selection	1354796
46084195	46084218	11	-	26627737	RPE1	viability after 18 days	GGAGTTGCAGACTCTACAGGAGG	PHF21A	ENSG00000135365	-1.0857639536760102	[685]	[49,126]	-6	hSpCas9	negative selection	1354797
45965383	45965406	11	+	26627737	HeLa	viability after 8 days	CTATCACAATGCTGGTGAGCTGG	PHF21A	ENSG00000135365	0.23321485880670206	[357]	[241,43,269]	2	hSpCas9	negative selection	1437107
45969816	45969839	11	+	26627737	HeLa	viability after 8 days	TGTGGAAGAAAGTTTGGACGTGG	PHF21A	ENSG00000135365	0.2919582480859858	[677]	[277,510,281]	2	hSpCas9	negative selection	1437108
45971242	45971265	11	+	26627737	HeLa	viability after 8 days	GATGGCGGTCACCATAGCAATGG	PHF21A	ENSG00000135365	-0.3268917777962397	[201]	[122,0,95]	-3	hSpCas9	negative selection	1437109
46049431	46049454	11	+	26627737	HeLa	viability after 8 days	CACAGTGTATTCCTGTACAGTGG	PHF21A	ENSG00000135365	-0.6759975468551018	[1030]	[474,171,240]	-6	hSpCas9	negative selection	1437110
46079142	46079165	11	-	26627737	HeLa	viability after 8 days	ACTGGTTGCTCAAATGAAGCAGG	PHF21A	ENSG00000135365	-0.2187121219113029	[381]	[188,81,165]	-2	hSpCas9	negative selection	1437111
46084195	46084218	11	-	26627737	HeLa	viability after 8 days	GGAGTTGCAGACTCTACAGGAGG	PHF21A	ENSG00000135365	-1.5982936254820472	[364]	[104,56,9]	-9	hSpCas9	negative selection	1437112
45965383	45965406	11	+	26627737	HeLa	viability after 12 days	CTATCACAATGCTGGTGAGCTGG	PHF21A	ENSG00000135365	1.0507943604795225	[357]	[302,281,336]	7	hSpCas9	negative selection	1519422
45969816	45969839	11	+	26627737	HeLa	viability after 12 days	TGTGGAAGAAAGTTTGGACGTGG	PHF21A	ENSG00000135365	-0.8114626279892305	[677]	[69,247,148]	-6	hSpCas9	negative selection	1519423
45971242	45971265	11	+	26627737	HeLa	viability after 12 days	GATGGCGGTCACCATAGCAATGG	PHF21A	ENSG00000135365	-0.3247693141797068	[201]	[93,35,73]	-3	hSpCas9	negative selection	1519424
46049431	46049454	11	+	26627737	HeLa	viability after 12 days	CACAGTGTATTCCTGTACAGTGG	PHF21A	ENSG00000135365	-0.8021964154241261	[1030]	[430,125,193]	-6	hSpCas9	negative selection	1519425
46079142	46079165	11	-	26627737	HeLa	viability after 12 days	ACTGGTTGCTCAAATGAAGCAGG	PHF21A	ENSG00000135365	0.33122521396830334	[381]	[360,99,149]	3	hSpCas9	negative selection	1519426
46084195	46084218	11	-	26627737	HeLa	viability after 12 days	GGAGTTGCAGACTCTACAGGAGG	PHF21A	ENSG00000135365	-1.345920865685373	[364]	[110,35,34]	-8	hSpCas9	negative selection	1519427
45965383	45965406	11	+	26627737	HeLa	viability after 15 days	CTATCACAATGCTGGTGAGCTGG	PHF21A	ENSG00000135365	0.7812239020794711	[357]	[170,287,296]	6	hSpCas9	negative selection	1601737
45969816	45969839	11	+	26627737	HeLa	viability after 15 days	TGTGGAAGAAAGTTTGGACGTGG	PHF21A	ENSG00000135365	-0.8915587127571112	[677]	[80,207,158]	-7	hSpCas9	negative selection	1601738
45971242	45971265	11	+	26627737	HeLa	viability after 15 days	GATGGCGGTCACCATAGCAATGG	PHF21A	ENSG00000135365	-2.7021226387172677	[201]	[0,0,37]	-9	hSpCas9	negative selection	1601739
46049431	46049454	11	+	26627737	HeLa	viability after 15 days	CACAGTGTATTCCTGTACAGTGG	PHF21A	ENSG00000135365	-1.2438024123611844	[1030]	[133,211,186]	-8	hSpCas9	negative selection	1601740
46079142	46079165	11	-	26627737	HeLa	viability after 15 days	ACTGGTTGCTCAAATGAAGCAGG	PHF21A	ENSG00000135365	-0.0863638338581147	[381]	[115,138,187]	0	hSpCas9	negative selection	1601741
46084195	46084218	11	-	26627737	HeLa	viability after 15 days	GGAGTTGCAGACTCTACAGGAGG	PHF21A	ENSG00000135365	-1.1889328964719055	[364]	[55,33,108]	-8	hSpCas9	negative selection	1601742
45965383	45965406	11	+	26627737	HeLa	viability after 18 days	CTATCACAATGCTGGTGAGCTGG	PHF21A	ENSG00000135365	0.7944511087711976	[357]	[113,244,296]	6	hSpCas9	negative selection	1684052
45969816	45969839	11	+	26627737	HeLa	viability after 18 days	TGTGGAAGAAAGTTTGGACGTGG	PHF21A	ENSG00000135365	-0.9153422292097133	[677]	[52,167,158]	-7	hSpCas9	negative selection	1684053
45971242	45971265	11	+	26627737	HeLa	viability after 18 days	GATGGCGGTCACCATAGCAATGG	PHF21A	ENSG00000135365	-2.674992583843075	[201]	[0,0,37]	-9	hSpCas9	negative selection	1684054
46049431	46049454	11	+	26627737	HeLa	viability after 18 days	CACAGTGTATTCCTGTACAGTGG	PHF21A	ENSG00000135365	-1.2740079229541572	[1030]	[87,168,186]	-8	hSpCas9	negative selection	1684055
46079142	46079165	11	-	26627737	HeLa	viability after 18 days	ACTGGTTGCTCAAATGAAGCAGG	PHF21A	ENSG00000135365	-0.09198864371929523	[381]	[71,120,187]	-1	hSpCas9	negative selection	1684056
46084195	46084218	11	-	26627737	HeLa	viability after 18 days	GGAGTTGCAGACTCTACAGGAGG	PHF21A	ENSG00000135365	-1.1145978406400356	[364]	[41,30,108]	-7	hSpCas9	negative selection	1684057
45965383	45965406	11	+	26627737	HCT116	viability after 6 days	CTATCACAATGCTGGTGAGCTGG	PHF21A	ENSG00000135365	1.0368613406693576	[496]	[178,149]	5	hSpCas9	negative selection	1766367
45969816	45969839	11	+	26627737	HCT116	viability after 6 days	TGTGGAAGAAAGTTTGGACGTGG	PHF21A	ENSG00000135365	-0.12942891812914192	[1201]	[213,149]	0	hSpCas9	negative selection	1766368
45971242	45971265	11	+	26627737	HCT116	viability after 6 days	GATGGCGGTCACCATAGCAATGG	PHF21A	ENSG00000135365	-1.6399729961343767	[184]	[18,3]	-7	hSpCas9	negative selection	1766369
46049431	46049454	11	+	26627737	HCT116	viability after 6 days	CACAGTGTATTCCTGTACAGTGG	PHF21A	ENSG00000135365	0.8912861787523603	[748]	[336,152]	5	hSpCas9	negative selection	1766370
46079142	46079165	11	-	26627737	HCT116	viability after 6 days	ACTGGTTGCTCAAATGAAGCAGG	PHF21A	ENSG00000135365	1.7576114085401793	[429]	[225,229]	8	hSpCas9	negative selection	1766371
46084195	46084218	11	-	26627737	HCT116	viability after 6 days	GGAGTTGCAGACTCTACAGGAGG	PHF21A	ENSG00000135365	-0.2694725360296167	[546]	[22,97]	-1	hSpCas9	negative selection	1766372
45965383	45965406	11	+	26627737	HCT116	viability after 8 days	CTATCACAATGCTGGTGAGCTGG	PHF21A	ENSG00000135365	1.8481367937009374	[115]	[194,283,210]	9	hSpCas9	negative selection	1848682
45969816	45969839	11	+	26627737	HCT116	viability after 8 days	TGTGGAAGAAAGTTTGGACGTGG	PHF21A	ENSG00000135365	0.051681009141424705	[469]	[299,249,255]	0	hSpCas9	negative selection	1848683
45971242	45971265	11	+	26627737	HCT116	viability after 8 days	GATGGCGGTCACCATAGCAATGG	PHF21A	ENSG00000135365	-1.0234508378801404	[204]	[65,53,46]	-8	hSpCas9	negative selection	1848684
46049431	46049454	11	+	26627737	HCT116	viability after 8 days	CACAGTGTATTCCTGTACAGTGG	PHF21A	ENSG00000135365	-0.060954573789597344	[817]	[431,326,535]	0	hSpCas9	negative selection	1848685
46079142	46079165	11	-	26627737	HCT116	viability after 8 days	ACTGGTTGCTCAAATGAAGCAGG	PHF21A	ENSG00000135365	0.3628318259391137	[242]	[222,165,128]	4	hSpCas9	negative selection	1848686
46084195	46084218	11	-	26627737	HCT116	viability after 8 days	GGAGTTGCAGACTCTACAGGAGG	PHF21A	ENSG00000135365	-1.068713996118385	[221]	[65,42,65]	-8	hSpCas9	negative selection	1848687
45965383	45965406	11	+	26627737	HCT116	viability after 9 days	CTATCACAATGCTGGTGAGCTGG	PHF21A	ENSG00000135365	1.3767948929773697	[496]	[123,518]	8	hSpCas9	negative selection	1930997
45969816	45969839	11	+	26627737	HCT116	viability after 9 days	TGTGGAAGAAAGTTTGGACGTGG	PHF21A	ENSG00000135365	0.24205002879543225	[1201]	[559,236]	1	hSpCas9	negative selection	1930998
45971242	45971265	11	+	26627737	HCT116	viability after 9 days	GATGGCGGTCACCATAGCAATGG	PHF21A	ENSG00000135365	0.6548387576405759	[184]	[36,109]	5	hSpCas9	negative selection	1930999
46049431	46049454	11	+	26627737	HCT116	viability after 9 days	CACAGTGTATTCCTGTACAGTGG	PHF21A	ENSG00000135365	0.6839329378043641	[748]	[389,266]	5	hSpCas9	negative selection	1931000
46079142	46079165	11	-	26627737	HCT116	viability after 9 days	ACTGGTTGCTCAAATGAAGCAGG	PHF21A	ENSG00000135365	-0.5062442087455895	[429]	[110,56]	-4	hSpCas9	negative selection	1931001
46084195	46084218	11	-	26627737	HCT116	viability after 9 days	GGAGTTGCAGACTCTACAGGAGG	PHF21A	ENSG00000135365	-0.781169192259597	[546]	[65,99]	-5	hSpCas9	negative selection	1931002
45965383	45965406	11	+	26627737	HCT116	viability after 12 days	CTATCACAATGCTGGTGAGCTGG	PHF21A	ENSG00000135365	1.209362443422406	[115]	[129,146,146]	8	hSpCas9	negative selection	2013312
45969816	45969839	11	+	26627737	HCT116	viability after 12 days	TGTGGAAGAAAGTTTGGACGTGG	PHF21A	ENSG00000135365	0.2715442956082844	[469]	[224,261,412]	2	hSpCas9	negative selection	2013313
45971242	45971265	11	+	26627737	HCT116	viability after 12 days	GATGGCGGTCACCATAGCAATGG	PHF21A	ENSG00000135365	-0.3442827285198079	[204]	[112,38,98]	-4	hSpCas9	negative selection	2013314
46049431	46049454	11	+	26627737	HCT116	viability after 12 days	CACAGTGTATTCCTGTACAGTGG	PHF21A	ENSG00000135365	-0.3520961947311525	[817]	[307,464,242]	-4	hSpCas9	negative selection	2013315
46079142	46079165	11	-	26627737	HCT116	viability after 12 days	ACTGGTTGCTCAAATGAAGCAGG	PHF21A	ENSG00000135365	0.3320952065583661	[242]	[169,182,128]	3	hSpCas9	negative selection	2013316
46084195	46084218	11	-	26627737	HCT116	viability after 12 days	GGAGTTGCAGACTCTACAGGAGG	PHF21A	ENSG00000135365	-0.38524641034679685	[221]	[63,80,124]	-4	hSpCas9	negative selection	2013317
45965383	45965406	11	+	26627737	HCT116	viability after 15 days	CTATCACAATGCTGGTGAGCTGG	PHF21A	ENSG00000135365	1.641649679756335	[115]	[145,256,212]	9	hSpCas9	negative selection	2095627
45969816	45969839	11	+	26627737	HCT116	viability after 15 days	TGTGGAAGAAAGTTTGGACGTGG	PHF21A	ENSG00000135365	0.26123377058787245	[469]	[326,243,398]	2	hSpCas9	negative selection	2095628
45971242	45971265	11	+	26627737	HCT116	viability after 15 days	GATGGCGGTCACCATAGCAATGG	PHF21A	ENSG00000135365	-0.390548969412143	[204]	[175,20,82]	-4	hSpCas9	negative selection	2095629
46049431	46049454	11	+	26627737	HCT116	viability after 15 days	CACAGTGTATTCCTGTACAGTGG	PHF21A	ENSG00000135365	-0.3154241123391961	[817]	[302,485,334]	-3	hSpCas9	negative selection	2095630
46079142	46079165	11	-	26627737	HCT116	viability after 15 days	ACTGGTTGCTCAAATGAAGCAGG	PHF21A	ENSG00000135365	0.08124167267315255	[242]	[153,167,121]	0	hSpCas9	negative selection	2095631
46084195	46084218	11	-	26627737	HCT116	viability after 15 days	GGAGTTGCAGACTCTACAGGAGG	PHF21A	ENSG00000135365	-0.5771708232328638	[221]	[134,91,35]	-5	hSpCas9	negative selection	2095632
45965383	45965406	11	+	26627737	HCT116	viability after 18 days	CTATCACAATGCTGGTGAGCTGG	PHF21A	ENSG00000135365	2.009972111830017	[115]	[220,121,346]	9	hSpCas9	negative selection	2177942
45969816	45969839	11	+	26627737	HCT116	viability after 18 days	TGTGGAAGAAAGTTTGGACGTGG	PHF21A	ENSG00000135365	0.30865021743733956	[469]	[199,282,364]	2	hSpCas9	negative selection	2177943
45971242	45971265	11	+	26627737	HCT116	viability after 18 days	GATGGCGGTCACCATAGCAATGG	PHF21A	ENSG00000135365	-1.2563334727593807	[204]	[58,3,64]	-8	hSpCas9	negative selection	2177944
46049431	46049454	11	+	26627737	HCT116	viability after 18 days	CACAGTGTATTCCTGTACAGTGG	PHF21A	ENSG00000135365	-0.2815829781642867	[817]	[435,185,364]	-3	hSpCas9	negative selection	2177945
46079142	46079165	11	-	26627737	HCT116	viability after 18 days	ACTGGTTGCTCAAATGAAGCAGG	PHF21A	ENSG00000135365	0.6695576329722426	[242]	[157,177,226]	5	hSpCas9	negative selection	2177946
46084195	46084218	11	-	26627737	HCT116	viability after 18 days	GGAGTTGCAGACTCTACAGGAGG	PHF21A	ENSG00000135365	-1.5100951075836764	[221]	[33,30,48]	-8	hSpCas9	negative selection	2177947
45979912	45979935	11	-	24336569	HL60	viability	GATAGTAAAGCAAGAACAACCGG	PHF21A	ENSG00000135365	0.4502109917786137	[477]	[1381]	4	hSpCas9	negative selection	2283866
45979943	45979966	11	-	24336569	HL60	viability	AAAGAGTAGTTGAACAGCTACGG	PHF21A	ENSG00000135365	-0.1112626479072108	[586]	[1149]	-1	hSpCas9	negative selection	2283867
46076753	46076776	11	-	24336569	HL60	viability	CACAGCTTTGAGTGAGAAACAGG	PHF21A	ENSG00000135365	-0.1391117596287121	[433]	[833]	-1	hSpCas9	negative selection	2283868
46079133	46079156	11	-	24336569	HL60	viability	TCAAATGAAGCAGGATCCACAGG	PHF21A	ENSG00000135365	-0.7321810468337668	[1211]	[1543]	-6	hSpCas9	negative selection	2283869
46079142	46079165	11	-	24336569	HL60	viability	ACTGGTTGCTCAAATGAAGCAGG	PHF21A	ENSG00000135365	0.7351241012067449	[355]	[1253]	6	hSpCas9	negative selection	2283870
46079148	46079171	11	+	24336569	HL60	viability	TCATTTGAGCAACCAGTTTCTGG	PHF21A	ENSG00000135365	-0.9611698669111843	[551]	[599]	-7	hSpCas9	negative selection	2283871
46084165	46084188	11	-	24336569	HL60	viability	AGTGGAAATTCAGGTTCACCAGG	PHF21A	ENSG00000135365	0.6098503812645939	[365]	[1181]	5	hSpCas9	negative selection	2283872
46084174	46084197	11	-	24336569	HL60	viability	GGCTCTTAAAGTGGAAATTCAGG	PHF21A	ENSG00000135365	-0.023431979257481084	[267]	[557]	0	hSpCas9	negative selection	2283873
46084183	46084206	11	-	24336569	HL60	viability	TCTACAGGAGGCTCTTAAAGTGG	PHF21A	ENSG00000135365	-0.0763931110814744	[283]	[569]	0	hSpCas9	negative selection	2283874
46084195	46084218	11	-	24336569	HL60	viability	GGAGTTGCAGACTCTACAGGAGG	PHF21A	ENSG00000135365	-0.1806124215017182	[398]	[744]	-1	hSpCas9	negative selection	2283875
45979912	45979935	11	-	24336569	KBM7	viability	GATAGTAAAGCAAGAACAACCGG	PHF21A	ENSG00000135365	0.1765374186899238	[520]	[1605]	1	hSpCas9	negative selection	2351043
45979943	45979966	11	-	24336569	KBM7	viability	AAAGAGTAGTTGAACAGCTACGG	PHF21A	ENSG00000135365	0.14451276823037873	[470]	[1419]	1	hSpCas9	negative selection	2351044
46076753	46076776	11	-	24336569	KBM7	viability	CACAGCTTTGAGTGAGAAACAGG	PHF21A	ENSG00000135365	0.7062261395301528	[219]	[978]	6	hSpCas9	negative selection	2351045
46079133	46079156	11	-	24336569	KBM7	viability	TCAAATGAAGCAGGATCCACAGG	PHF21A	ENSG00000135365	-0.9811003119201693	[853]	[1179]	-6	hSpCas9	negative selection	2351046
46079142	46079165	11	-	24336569	KBM7	viability	ACTGGTTGCTCAAATGAAGCAGG	PHF21A	ENSG00000135365	0.6116600068257936	[333]	[1391]	5	hSpCas9	negative selection	2351047
46079148	46079171	11	+	24336569	KBM7	viability	TCATTTGAGCAACCAGTTTCTGG	PHF21A	ENSG00000135365	0.46756809583415027	[301]	[1138]	4	hSpCas9	negative selection	2351048
46084165	46084188	11	-	24336569	KBM7	viability	AGTGGAAATTCAGGTTCACCAGG	PHF21A	ENSG00000135365	0.4495058861647337	[373]	[1392]	4	hSpCas9	negative selection	2351049
46084174	46084197	11	-	24336569	KBM7	viability	GGCTCTTAAAGTGGAAATTCAGG	PHF21A	ENSG00000135365	-0.22991434374941924	[392]	[913]	-2	hSpCas9	negative selection	2351050
46084183	46084206	11	-	24336569	KBM7	viability	TCTACAGGAGGCTCTTAAAGTGG	PHF21A	ENSG00000135365	0.01185242208841486	[115]	[318]	0	hSpCas9	negative selection	2351051
46084195	46084218	11	-	24336569	KBM7	viability	GGAGTTGCAGACTCTACAGGAGG	PHF21A	ENSG00000135365	-0.041586836873045645	[399]	[1059]	0	hSpCas9	negative selection	2351052
46028767	46028790	11	+	25494202	A375	resistance to PLX-4720 (puromycin)	TTTCACCATGTTGGTCAGGCTAG	PHF21A	ENSG00000135365	-0.9950505910624323	[34,30]	[4,1]	-6	dCas9-VP64	positive selection	2385276
45998967	45998990	11	+	25494202	A375	resistance to PLX-4720 (puromycin)	CAGGCACCTGCCACCACGCCTGG	PHF21A	ENSG00000135365	3.5563442726279137	[263,282]	[1245,134]	9	dCas9-VP64	positive selection	2389838
45943145	45943168	11	+	25494202	A375	resistance to PLX-4720 (puromycin)	CAGGGTCTTGTTCTGTCACCCAG	PHF21A	ENSG00000135365	1.8873495753995055	[277,92]	[61,243]	6	dCas9-VP64	positive selection	2402498
46094772	46094795	11	+	25494202	A375	resistance to PLX-4720 (puromycin)	CACCTGTAATCTCAGCTACTCGG	PHF21A	ENSG00000135365	-0.32009396436001514	[73,465]	[65,28]	-1	dCas9-VP64	positive selection	2454618
45939112	45939135	11	+	25494202	A375	resistance to PLX-4720 (puromycin)	GTGAGCCACTGCACCCGGCCGGG	PHF21A	ENSG00000135365	1.1797326428655701	[26,26]	[14,10]	4	dCas9-VP64	positive selection	2469478
46028767	46028790	11	+	25494202	A375	resistance to PLX-4720 (zeocin)	TTTCACCATGTTGGTCAGGCTAG	PHF21A	ENSG00000135365	-0.9351084987288634	[176,47]	[27,9]	-8	dCas9-VP64	positive selection	2480531
45998967	45998990	11	+	25494202	A375	resistance to PLX-4720 (zeocin)	CAGGCACCTGCCACCACGCCTGG	PHF21A	ENSG00000135365	0.46315742416717276	[258,245]	[121,105]	3	dCas9-VP64	positive selection	2485093
45943145	45943168	11	+	25494202	A375	resistance to PLX-4720 (zeocin)	CAGGGTCTTGTTCTGTCACCCAG	PHF21A	ENSG00000135365	-0.6627118139888153	[169,193]	[38,34]	-6	dCas9-VP64	positive selection	2497753
46094772	46094795	11	+	25494202	A375	resistance to PLX-4720 (zeocin)	CACCTGTAATCTCAGCTACTCGG	PHF21A	ENSG00000135365	-0.35714226545986627	[161,80]	[51,10]	-4	dCas9-VP64	positive selection	2549873
45939112	45939135	11	+	25494202	A375	resistance to PLX-4720 (zeocin)	GTGAGCCACTGCACCCGGCCGGG	PHF21A	ENSG00000135365	0.8568341606696415	[42,16]	[22,11]	6	dCas9-VP64	positive selection	2564733
45971276	45971299	11	-	27260157	DLD1	viability	ACCATGCCTGCCTCTGTGGTGGG	PHF21A	ENSG00000135365	0.278376875754109	[]	[]	4	hSpCas9	negative selection	2575272
45979780	45979803	11	+	27260157	DLD1	viability	GAGAGGCTGCAGCTGACTGCTGG	PHF21A	ENSG00000135365	0.497915931165525	[]	[]	8	hSpCas9	negative selection	2576675
45979912	45979935	11	-	27260157	DLD1	viability	GATAGTAAAGCAAGAACAACCGG	PHF21A	ENSG00000135365	-1.18927087593626	[]	[]	-7	hSpCas9	negative selection	2576888
45979757	45979780	11	+	27260157	DLD1	viability	TACCTGTGAAGCAGTCAGGTTGG	PHF21A	ENSG00000135365	0.615053104674047	[]	[]	8	hSpCas9	negative selection	2580841
46079142	46079165	11	-	27260157	DLD1	viability	ACTGGTTGCTCAAATGAAGCAGG	PHF21A	ENSG00000135365	0.19024220359888	[]	[]	3	hSpCas9	negative selection	2581005
45971266	45971289	11	+	27260157	DLD1	viability	AGGTCTCTGGCCCACCACAGAGG	PHF21A	ENSG00000135365	0.181121006196619	[]	[]	3	hSpCas9	negative selection	2583383
45971303	45971326	11	+	27260157	DLD1	viability	GTTGCTGCTTTCAAGACGAGAGG	PHF21A	ENSG00000135365	0.616639487331375	[]	[]	8	hSpCas9	negative selection	2585480
45971253	45971276	11	-	27260157	DLD1	viability	CCAGAGACCTACCATTGCTATGG	PHF21A	ENSG00000135365	-0.0156973726388948	[]	[]	0	hSpCas9	negative selection	2587002
45979792	45979815	11	+	27260157	DLD1	viability	CTGACTGCTGGGCGTGGTGGTGG	PHF21A	ENSG00000135365	-0.745224525551428	[]	[]	-5	hSpCas9	negative selection	2587108
45979943	45979966	11	-	27260157	DLD1	viability	AAAGAGTAGTTGAACAGCTACGG	PHF21A	ENSG00000135365	0.352429446506375	[]	[]	4	hSpCas9	negative selection	2605036
46084174	46084197	11	-	27260157	DLD1	viability	GGCTCTTAAAGTGGAAATTCAGG	PHF21A	ENSG00000135365	-0.276609757468767	[]	[]	-2	hSpCas9	negative selection	2605843
45971317	45971340	11	+	27260157	DLD1	viability	GACGAGAGGTAGTGTCTTTGTGG	PHF21A	ENSG00000135365	-0.0674610169935984	[]	[]	0	hSpCas9	negative selection	2607409
45979893	45979916	11	+	27260157	DLD1	viability	GGCTGTATTTGGAACTTGTCCGG	PHF21A	ENSG00000135365	-0.638436516906893	[]	[]	-5	hSpCas9	negative selection	2607539
46076753	46076776	11	-	27260157	DLD1	viability	CACAGCTTTGAGTGAGAAACAGG	PHF21A	ENSG00000135365	0.513734878622183	[]	[]	8	hSpCas9	negative selection	2609221
45971253	45971276	11	+	27260157	DLD1	viability	CCATAGCAATGGTAGGTCTCTGG	PHF21A	ENSG00000135365	0.379463602564289	[]	[]	4	hSpCas9	negative selection	2615155
46084183	46084206	11	-	27260157	DLD1	viability	TCTACAGGAGGCTCTTAAAGTGG	PHF21A	ENSG00000135365	-0.359355848410025	[]	[]	-3	hSpCas9	negative selection	2615856
46084195	46084218	11	-	27260157	DLD1	viability	GGAGTTGCAGACTCTACAGGAGG	PHF21A	ENSG00000135365	1.26371077708703	[]	[]	9	hSpCas9	negative selection	2620422
46079148	46079171	11	+	27260157	DLD1	viability	TCATTTGAGCAACCAGTTTCTGG	PHF21A	ENSG00000135365	-0.0202468108597941	[]	[]	0	hSpCas9	negative selection	2623707
46084165	46084188	11	-	27260157	DLD1	viability	AGTGGAAATTCAGGTTCACCAGG	PHF21A	ENSG00000135365	0.503580428726943	[]	[]	8	hSpCas9	negative selection	2644891
46079133	46079156	11	-	27260157	DLD1	viability	TCAAATGAAGCAGGATCCACAGG	PHF21A	ENSG00000135365	0.841772931284593	[]	[]	9	hSpCas9	negative selection	2647314
45971276	45971299	11	-	27260157	HT1080	viability	ACCATGCCTGCCTCTGTGGTGGG	PHF21A	ENSG00000135365	-0.180196155827434	[]	[]	0	hSpCas9	negative selection	2651402
45979780	45979803	11	+	27260157	HT1080	viability	GAGAGGCTGCAGCTGACTGCTGG	PHF21A	ENSG00000135365	1.82713189794798	[]	[]	9	hSpCas9	negative selection	2652805
45979912	45979935	11	-	27260157	HT1080	viability	GATAGTAAAGCAAGAACAACCGG	PHF21A	ENSG00000135365	1.41167296164098	[]	[]	9	hSpCas9	negative selection	2653018
45979757	45979780	11	+	27260157	HT1080	viability	TACCTGTGAAGCAGTCAGGTTGG	PHF21A	ENSG00000135365	-0.375823087263489	[]	[]	-7	hSpCas9	negative selection	2656971
46079142	46079165	11	-	27260157	HT1080	viability	ACTGGTTGCTCAAATGAAGCAGG	PHF21A	ENSG00000135365	0.379910169450027	[]	[]	3	hSpCas9	negative selection	2657135
45971266	45971289	11	+	27260157	HT1080	viability	AGGTCTCTGGCCCACCACAGAGG	PHF21A	ENSG00000135365	-1.0004353797662	[]	[]	-8	hSpCas9	negative selection	2659513
45971303	45971326	11	+	27260157	HT1080	viability	GTTGCTGCTTTCAAGACGAGAGG	PHF21A	ENSG00000135365	-0.245135995132667	[]	[]	0	hSpCas9	negative selection	2661610
45971253	45971276	11	-	27260157	HT1080	viability	CCAGAGACCTACCATTGCTATGG	PHF21A	ENSG00000135365	0.407643148138472	[]	[]	3	hSpCas9	negative selection	2663132
45979792	45979815	11	+	27260157	HT1080	viability	CTGACTGCTGGGCGTGGTGGTGG	PHF21A	ENSG00000135365	-0.341507280593816	[]	[]	-7	hSpCas9	negative selection	2663238
45979943	45979966	11	-	27260157	HT1080	viability	AAAGAGTAGTTGAACAGCTACGG	PHF21A	ENSG00000135365	0.767737708694688	[]	[]	6	hSpCas9	negative selection	2681166
46084174	46084197	11	-	27260157	HT1080	viability	GGCTCTTAAAGTGGAAATTCAGG	PHF21A	ENSG00000135365	0.293414571642531	[]	[]	2	hSpCas9	negative selection	2681973
45971317	45971340	11	+	27260157	HT1080	viability	GACGAGAGGTAGTGTCTTTGTGG	PHF21A	ENSG00000135365	0.441181588902928	[]	[]	4	hSpCas9	negative selection	2683539
45979893	45979916	11	+	27260157	HT1080	viability	GGCTGTATTTGGAACTTGTCCGG	PHF21A	ENSG00000135365	-0.721495880155521	[]	[]	-8	hSpCas9	negative selection	2683669
46076753	46076776	11	-	27260157	HT1080	viability	CACAGCTTTGAGTGAGAAACAGG	PHF21A	ENSG00000135365	0.390537526053688	[]	[]	3	hSpCas9	negative selection	2685351
45971253	45971276	11	+	27260157	HT1080	viability	CCATAGCAATGGTAGGTCTCTGG	PHF21A	ENSG00000135365	0.152117802048707	[]	[]	1	hSpCas9	negative selection	2691285
46084183	46084206	11	-	27260157	HT1080	viability	TCTACAGGAGGCTCTTAAAGTGG	PHF21A	ENSG00000135365	-0.150939571396931	[]	[]	0	hSpCas9	negative selection	2691986
46084195	46084218	11	-	27260157	HT1080	viability	GGAGTTGCAGACTCTACAGGAGG	PHF21A	ENSG00000135365	-0.398319912034563	[]	[]	-7	hSpCas9	negative selection	2696552
46079148	46079171	11	+	27260157	HT1080	viability	TCATTTGAGCAACCAGTTTCTGG	PHF21A	ENSG00000135365	-0.387115598303532	[]	[]	-7	hSpCas9	negative selection	2699837
46084165	46084188	11	-	27260157	HT1080	viability	AGTGGAAATTCAGGTTCACCAGG	PHF21A	ENSG00000135365	0.000791012171116364	[]	[]	0	hSpCas9	negative selection	2721021
46079133	46079156	11	-	27260157	HT1080	viability	TCAAATGAAGCAGGATCCACAGG	PHF21A	ENSG00000135365	0.282302176635149	[]	[]	2	hSpCas9	negative selection	2723444
45971276	45971299	11	-	27260157	MKN45	viability	ACCATGCCTGCCTCTGTGGTGGG	PHF21A	ENSG00000135365	-0.146912644773916	[]	[]	0	hSpCas9	negative selection	2727532
45979780	45979803	11	+	27260157	MKN45	viability	GAGAGGCTGCAGCTGACTGCTGG	PHF21A	ENSG00000135365	1.00910402600489	[]	[]	8	hSpCas9	negative selection	2728935
45979912	45979935	11	-	27260157	MKN45	viability	GATAGTAAAGCAAGAACAACCGG	PHF21A	ENSG00000135365	0.849337850637943	[]	[]	8	hSpCas9	negative selection	2729148
45979757	45979780	11	+	27260157	MKN45	viability	TACCTGTGAAGCAGTCAGGTTGG	PHF21A	ENSG00000135365	0.0206072754803438	[]	[]	0	hSpCas9	negative selection	2733101
46079142	46079165	11	-	27260157	MKN45	viability	ACTGGTTGCTCAAATGAAGCAGG	PHF21A	ENSG00000135365	0.603994635585851	[]	[]	7	hSpCas9	negative selection	2733265
45971266	45971289	11	+	27260157	MKN45	viability	AGGTCTCTGGCCCACCACAGAGG	PHF21A	ENSG00000135365	-0.581262021564181	[]	[]	-6	hSpCas9	negative selection	2735643
45971303	45971326	11	+	27260157	MKN45	viability	GTTGCTGCTTTCAAGACGAGAGG	PHF21A	ENSG00000135365	0.668669926059396	[]	[]	7	hSpCas9	negative selection	2737740
45971253	45971276	11	-	27260157	MKN45	viability	CCAGAGACCTACCATTGCTATGG	PHF21A	ENSG00000135365	0.545415032219845	[]	[]	7	hSpCas9	negative selection	2739262
45979792	45979815	11	+	27260157	MKN45	viability	CTGACTGCTGGGCGTGGTGGTGG	PHF21A	ENSG00000135365	-0.733084825588212	[]	[]	-7	hSpCas9	negative selection	2739368
45979943	45979966	11	-	27260157	MKN45	viability	AAAGAGTAGTTGAACAGCTACGG	PHF21A	ENSG00000135365	-0.253136668814815	[]	[]	-1	hSpCas9	negative selection	2757296
46084174	46084197	11	-	27260157	MKN45	viability	GGCTCTTAAAGTGGAAATTCAGG	PHF21A	ENSG00000135365	-0.430720361873842	[]	[]	-6	hSpCas9	negative selection	2758103
45971317	45971340	11	+	27260157	MKN45	viability	GACGAGAGGTAGTGTCTTTGTGG	PHF21A	ENSG00000135365	0.22273180886688	[]	[]	5	hSpCas9	negative selection	2759669
45979893	45979916	11	+	27260157	MKN45	viability	GGCTGTATTTGGAACTTGTCCGG	PHF21A	ENSG00000135365	-0.190729285555322	[]	[]	0	hSpCas9	negative selection	2759799
46076753	46076776	11	-	27260157	MKN45	viability	CACAGCTTTGAGTGAGAAACAGG	PHF21A	ENSG00000135365	1.1916263216053	[]	[]	9	hSpCas9	negative selection	2761481
45971253	45971276	11	+	27260157	MKN45	viability	CCATAGCAATGGTAGGTCTCTGG	PHF21A	ENSG00000135365	0.0176111298802197	[]	[]	0	hSpCas9	negative selection	2767415
46084183	46084206	11	-	27260157	MKN45	viability	TCTACAGGAGGCTCTTAAAGTGG	PHF21A	ENSG00000135365	-0.133559359011971	[]	[]	0	hSpCas9	negative selection	2768116
46084195	46084218	11	-	27260157	MKN45	viability	GGAGTTGCAGACTCTACAGGAGG	PHF21A	ENSG00000135365	0.253776009862296	[]	[]	5	hSpCas9	negative selection	2772682
46079148	46079171	11	+	27260157	MKN45	viability	TCATTTGAGCAACCAGTTTCTGG	PHF21A	ENSG00000135365	-0.525876660116209	[]	[]	-6	hSpCas9	negative selection	2775967
46084165	46084188	11	-	27260157	MKN45	viability	AGTGGAAATTCAGGTTCACCAGG	PHF21A	ENSG00000135365	-0.0212352401424441	[]	[]	0	hSpCas9	negative selection	2797151
46079133	46079156	11	-	27260157	MKN45	viability	TCAAATGAAGCAGGATCCACAGG	PHF21A	ENSG00000135365	-0.208293834241879	[]	[]	0	hSpCas9	negative selection	2799574
45971276	45971299	11	-	27260157	RKO	viability	ACCATGCCTGCCTCTGTGGTGGG	PHF21A	ENSG00000135365	0.0820413647827647	[]	[]	0	hSpCas9	negative selection	2803662
45979780	45979803	11	+	27260157	RKO	viability	GAGAGGCTGCAGCTGACTGCTGG	PHF21A	ENSG00000135365	1.69719675335128	[]	[]	9	hSpCas9	negative selection	2805065
45979912	45979935	11	-	27260157	RKO	viability	GATAGTAAAGCAAGAACAACCGG	PHF21A	ENSG00000135365	0.225856134507647	[]	[]	1	hSpCas9	negative selection	2805278
45979757	45979780	11	+	27260157	RKO	viability	TACCTGTGAAGCAGTCAGGTTGG	PHF21A	ENSG00000135365	0.172848275519706	[]	[]	0	hSpCas9	negative selection	2809231
46079142	46079165	11	-	27260157	RKO	viability	ACTGGTTGCTCAAATGAAGCAGG	PHF21A	ENSG00000135365	1.01657727089103	[]	[]	9	hSpCas9	negative selection	2809395
45971266	45971289	11	+	27260157	RKO	viability	AGGTCTCTGGCCCACCACAGAGG	PHF21A	ENSG00000135365	-0.92415607236985	[]	[]	-8	hSpCas9	negative selection	2811773
45971303	45971326	11	+	27260157	RKO	viability	GTTGCTGCTTTCAAGACGAGAGG	PHF21A	ENSG00000135365	0.767005382332134	[]	[]	8	hSpCas9	negative selection	2813870
45971253	45971276	11	-	27260157	RKO	viability	CCAGAGACCTACCATTGCTATGG	PHF21A	ENSG00000135365	0.0127654773295258	[]	[]	0	hSpCas9	negative selection	2815392
45979792	45979815	11	+	27260157	RKO	viability	CTGACTGCTGGGCGTGGTGGTGG	PHF21A	ENSG00000135365	-1.03750296134708	[]	[]	-8	hSpCas9	negative selection	2815498
45979943	45979966	11	-	27260157	RKO	viability	AAAGAGTAGTTGAACAGCTACGG	PHF21A	ENSG00000135365	0.730938304654459	[]	[]	8	hSpCas9	negative selection	2833426
46084174	46084197	11	-	27260157	RKO	viability	GGCTCTTAAAGTGGAAATTCAGG	PHF21A	ENSG00000135365	0.000176150863691865	[]	[]	0	hSpCas9	negative selection	2834233
45971317	45971340	11	+	27260157	RKO	viability	GACGAGAGGTAGTGTCTTTGTGG	PHF21A	ENSG00000135365	0.0554140861554439	[]	[]	0	hSpCas9	negative selection	2835799
45979893	45979916	11	+	27260157	RKO	viability	GGCTGTATTTGGAACTTGTCCGG	PHF21A	ENSG00000135365	-0.156499755346713	[]	[]	0	hSpCas9	negative selection	2835929
46076753	46076776	11	-	27260157	RKO	viability	CACAGCTTTGAGTGAGAAACAGG	PHF21A	ENSG00000135365	0.882508105191054	[]	[]	8	hSpCas9	negative selection	2837611
45971253	45971276	11	+	27260157	RKO	viability	CCATAGCAATGGTAGGTCTCTGG	PHF21A	ENSG00000135365	0.287278540146719	[]	[]	1	hSpCas9	negative selection	2843545
46084183	46084206	11	-	27260157	RKO	viability	TCTACAGGAGGCTCTTAAAGTGG	PHF21A	ENSG00000135365	-0.118402347400909	[]	[]	0	hSpCas9	negative selection	2844246
46084195	46084218	11	-	27260157	RKO	viability	GGAGTTGCAGACTCTACAGGAGG	PHF21A	ENSG00000135365	0.247588167416123	[]	[]	1	hSpCas9	negative selection	2848812
46079148	46079171	11	+	27260157	RKO	viability	TCATTTGAGCAACCAGTTTCTGG	PHF21A	ENSG00000135365	0.365474649512433	[]	[]	2	hSpCas9	negative selection	2852097
46084165	46084188	11	-	27260157	RKO	viability	AGTGGAAATTCAGGTTCACCAGG	PHF21A	ENSG00000135365	1.00320873138501	[]	[]	9	hSpCas9	negative selection	2873281
46079133	46079156	11	-	27260157	RKO	viability	TCAAATGAAGCAGGATCCACAGG	PHF21A	ENSG00000135365	-0.63700496478334	[]	[]	-7	hSpCas9	negative selection	2875704
45971276	45971299	11	-	27260157	SF268	viability	ACCATGCCTGCCTCTGTGGTGGG	PHF21A	ENSG00000135365	-0.0153104341066667	[]	[]	0	hSpCas9	negative selection	2879792
45979780	45979803	11	+	27260157	SF268	viability	GAGAGGCTGCAGCTGACTGCTGG	PHF21A	ENSG00000135365	1.7620955694056	[]	[]	9	hSpCas9	negative selection	2881195
45979912	45979935	11	-	27260157	SF268	viability	GATAGTAAAGCAAGAACAACCGG	PHF21A	ENSG00000135365	0.00946091290873262	[]	[]	0	hSpCas9	negative selection	2881408
45979757	45979780	11	+	27260157	SF268	viability	TACCTGTGAAGCAGTCAGGTTGG	PHF21A	ENSG00000135365	-0.200099898607789	[]	[]	-1	hSpCas9	negative selection	2885361
46079142	46079165	11	-	27260157	SF268	viability	ACTGGTTGCTCAAATGAAGCAGG	PHF21A	ENSG00000135365	0.691309399983141	[]	[]	8	hSpCas9	negative selection	2885525
45971266	45971289	11	+	27260157	SF268	viability	AGGTCTCTGGCCCACCACAGAGG	PHF21A	ENSG00000135365	0.112231739650484	[]	[]	0	hSpCas9	negative selection	2887903
45971303	45971326	11	+	27260157	SF268	viability	GTTGCTGCTTTCAAGACGAGAGG	PHF21A	ENSG00000135365	0.815776499194349	[]	[]	8	hSpCas9	negative selection	2890000
45971253	45971276	11	-	27260157	SF268	viability	CCAGAGACCTACCATTGCTATGG	PHF21A	ENSG00000135365	0.72195510592627	[]	[]	8	hSpCas9	negative selection	2891522
45979792	45979815	11	+	27260157	SF268	viability	CTGACTGCTGGGCGTGGTGGTGG	PHF21A	ENSG00000135365	-0.744164576922031	[]	[]	-6	hSpCas9	negative selection	2891628
45979943	45979966	11	-	27260157	SF268	viability	AAAGAGTAGTTGAACAGCTACGG	PHF21A	ENSG00000135365	0.777353553187017	[]	[]	8	hSpCas9	negative selection	2909556
46084174	46084197	11	-	27260157	SF268	viability	GGCTCTTAAAGTGGAAATTCAGG	PHF21A	ENSG00000135365	0.0149048152703696	[]	[]	0	hSpCas9	negative selection	2910363
45971317	45971340	11	+	27260157	SF268	viability	GACGAGAGGTAGTGTCTTTGTGG	PHF21A	ENSG00000135365	-0.301931265489719	[]	[]	-2	hSpCas9	negative selection	2911929
45979893	45979916	11	+	27260157	SF268	viability	GGCTGTATTTGGAACTTGTCCGG	PHF21A	ENSG00000135365	-0.00677351717682045	[]	[]	0	hSpCas9	negative selection	2912059
46076753	46076776	11	-	27260157	SF268	viability	CACAGCTTTGAGTGAGAAACAGG	PHF21A	ENSG00000135365	0.182848525356099	[]	[]	0	hSpCas9	negative selection	2913741
45971253	45971276	11	+	27260157	SF268	viability	CCATAGCAATGGTAGGTCTCTGG	PHF21A	ENSG00000135365	0.62412877949716	[]	[]	8	hSpCas9	negative selection	2919675
46084183	46084206	11	-	27260157	SF268	viability	TCTACAGGAGGCTCTTAAAGTGG	PHF21A	ENSG00000135365	-0.580144201932955	[]	[]	-4	hSpCas9	negative selection	2920376
46084195	46084218	11	-	27260157	SF268	viability	GGAGTTGCAGACTCTACAGGAGG	PHF21A	ENSG00000135365	0.768443924285852	[]	[]	8	hSpCas9	negative selection	2924942
46079148	46079171	11	+	27260157	SF268	viability	TCATTTGAGCAACCAGTTTCTGG	PHF21A	ENSG00000135365	-0.542530955630424	[]	[]	-4	hSpCas9	negative selection	2928227
46084165	46084188	11	-	27260157	SF268	viability	AGTGGAAATTCAGGTTCACCAGG	PHF21A	ENSG00000135365	0.429824715706807	[]	[]	7	hSpCas9	negative selection	2949411
46079133	46079156	11	-	27260157	SF268	viability	TCAAATGAAGCAGGATCCACAGG	PHF21A	ENSG00000135365	0.491342254335328	[]	[]	7	hSpCas9	negative selection	2951834
45965372	45965395	11	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCATTGTGATAGCTACTCCAGGG	PHF21A	ENSG00000135365	0.33439496451189643	[3,4]	[5,3]	7	hSpCas9	positive selection	3011053
46076749	46076772	11	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCTTTGAGTGAGAAACAGGTAGG	PHF21A	ENSG00000135365	0.01566139343885222	[3,3]	[4,1]	0	hSpCas9	positive selection	3011054
46084195	46084218	11	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GGAGTTGCAGACTCTACAGGAGG	PHF21A	ENSG00000135365	-0.3269053639187254	[2,3]	[1,2]	-5	hSpCas9	positive selection	3011055
45971304	45971327	11	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GTTGCTGCTTTCAAGACGAGAGG	PHF21A	ENSG00000135365	-0.3003867150610354	[4,4]	[4,1]	-4	hSpCas9	positive selection	3011056
45965372	45965395	11	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCATTGTGATAGCTACTCCAGGG	PHF21A	ENSG00000135365	0.9429094762514695	[3,3]	[5,5]	9	hSpCas9	positive selection	3078911
46076749	46076772	11	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCTTTGAGTGAGAAACAGGTAGG	PHF21A	ENSG00000135365	0.42184907571103464	[3,3]	[3,3]	7	hSpCas9	positive selection	3078912
46084195	46084218	11	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GGAGTTGCAGACTCTACAGGAGG	PHF21A	ENSG00000135365	-0.2043331981999252	[2,2]	[3,0]	-3	hSpCas9	positive selection	3078913
45971304	45971327	11	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GTTGCTGCTTTCAAGACGAGAGG	PHF21A	ENSG00000135365	0.5003214674435299	[4,4]	[5,4]	8	hSpCas9	positive selection	3078914
46079142	46079165		-	24336571	A375	resistance to PLX after 7 days	ACTGGTTGCTCAAATGAAGCAGG	PHF21A	ENSG00000135365	0.12453839757360348	[13,13]	[15,13]	4	hSpCas9	positive selection	3135324
46084198	46084221		-	24336571	A375	resistance to PLX after 7 days	GATGGAGTTGCAGACTCTACAGG	PHF21A	ENSG00000135365	-0.042797272433075184	[16,17]	[14,17]	-1	hSpCas9	positive selection	3135325
46079142	46079165		-	24336571	A375	resistance to PLX after 14 days	ACTGGTTGCTCAAATGAAGCAGG	PHF21A	ENSG00000135365	1.3495918670793545	[7,14]	[14,12]	8	hSpCas9	positive selection	3193117
46084198	46084221		-	24336571	A375	resistance to PLX after 14 days	GATGGAGTTGCAGACTCTACAGG	PHF21A	ENSG00000135365	0.1206189512476511	[15,13]	[7,6]	1	hSpCas9	positive selection	3193118
46079142	46079165		-	24336571	A375	viability after 7 days	ACTGGTTGCTCAAATGAAGCAGG	PHF21A	ENSG00000135365	-0.2850272236594145	[17]	[13,13]	-4	hSpCas9	negative selection	3250910
46084198	46084221		-	24336571	A375	viability after 7 days	GATGGAGTTGCAGACTCTACAGG	PHF21A	ENSG00000135365	-0.29336518350023766	[21]	[16,17]	-4	hSpCas9	negative selection	3250911
46079142	46079165		-	24336571	A375	viability after 14 days	ACTGGTTGCTCAAATGAAGCAGG	PHF21A	ENSG00000135365	-0.5347996471510522	[17]	[7,14]	-6	hSpCas9	negative selection	3308703
46084198	46084221		-	24336571	A375	viability after 14 days	GATGGAGTTGCAGACTCTACAGG	PHF21A	ENSG00000135365	-0.4698948308634225	[21]	[15,13]	-5	hSpCas9	negative selection	3308704
45979759	45979782	11	-	27383988	293T	resistance to West Nile virus (flavivirus)	TCCCAACCTGACTGCTTCACAGG	PHF21A	ENSG00000135365	-1.6435405965349135	[477,477]	[0,0]	-9	hSpCas9	positive selection	3385642
46084174	46084197	11	-	27383988	293T	resistance to West Nile virus (flavivirus)	GGCTCTTAAAGTGGAAATTCAGG	PHF21A	ENSG00000135365	2.4499712893882313	[27,27]	[0,0]	8	hSpCas9	positive selection	3385643
45979943	45979966	11	-	27383988	293T	resistance to West Nile virus (flavivirus)	AAAGAGTAGTTGAACAGCTACGG	PHF21A	ENSG00000135365	-0.12637808102821713	[166,166]	[0,0]	0	hSpCas9	positive selection	3385644
45965372	45965395	11	-	26780180	HT29	viability (Avana library 4 designs)	GCATTGTGATAGCTACTCCAGGG	PHF21A	ENSG00000135365	0.422501824961302	[]	[]	1	hSpCas9	negative selection	3449128
46076749	46076772	11	-	26780180	HT29	viability (Avana library 4 designs)	GCTTTGAGTGAGAAACAGGTAGG	PHF21A	ENSG00000135365	0.0418093952135814	[]	[]	0	hSpCas9	negative selection	3449129
46084195	46084218	11	-	26780180	HT29	viability (Avana library 4 designs)	GGAGTTGCAGACTCTACAGGAGG	PHF21A	ENSG00000135365	0.978278090694244	[]	[]	4	hSpCas9	negative selection	3449130
45971303	45971326	11	+	26780180	HT29	viability (Avana library 4 designs)	GTTGCTGCTTTCAAGACGAGAGG	PHF21A	ENSG00000135365	-0.651390867849108	[]	[]	-8	hSpCas9	negative selection	3449131
45971303	45971326	11	+	26780180	A375	viability (Avana lentiCRISPRv2)	GTTGCTGCTTTCAAGACGAGAGG	PHF21A	ENSG00000135365	3.74687700881946	[]	[]	6	hSpCas9	negative selection	3543741
45965372	45965395	11	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCATTGTGATAGCTACTCCAGGG	PHF21A	ENSG00000135365	-4.25948474228796	[]	[]	-5	hSpCas9	negative selection	3543742
46076749	46076772	11	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCTTTGAGTGAGAAACAGGTAGG	PHF21A	ENSG00000135365	-1.19741578886334	[]	[]	-1	hSpCas9	negative selection	3543743
46084195	46084218	11	-	26780180	A375	viability (Avana lentiCRISPRv2)	GGAGTTGCAGACTCTACAGGAGG	PHF21A	ENSG00000135365	0.902953557217943	[]	[]	1	hSpCas9	negative selection	3543744
45965522	45965545	11	-	26780180	A375	viability (Avana lentiCRISPRv2)	CAGCTCCTCAGCTTATCCAGAGG	PHF21A	ENSG00000135365	-1.93954288294318	[]	[]	-2	hSpCas9	negative selection	3543745
45971242	45971265	11	+	26780180	A375	viability (Avana lentiCRISPRv2)	GATGGCGGTCACCATAGCAATGG	PHF21A	ENSG00000135365	3.91617466778439	[]	[]	6	hSpCas9	negative selection	3543746
45971303	45971326	11	+	26780180	A375	viability (Avana lentiGuide)	GTTGCTGCTTTCAAGACGAGAGG	PHF21A	ENSG00000135365	-0.726852782516861	[]	[]	-1	hSpCas9	negative selection	3652400
45965372	45965395	11	-	26780180	A375	viability (Avana lentiGuide)	GCATTGTGATAGCTACTCCAGGG	PHF21A	ENSG00000135365	3.5903633108713	[]	[]	3	hSpCas9	negative selection	3652401
46076749	46076772	11	-	26780180	A375	viability (Avana lentiGuide)	GCTTTGAGTGAGAAACAGGTAGG	PHF21A	ENSG00000135365	-3.4607970105236	[]	[]	-6	hSpCas9	negative selection	3652402
46084195	46084218	11	-	26780180	A375	viability (Avana lentiGuide)	GGAGTTGCAGACTCTACAGGAGG	PHF21A	ENSG00000135365	2.04179270830335	[]	[]	2	hSpCas9	negative selection	3652403
45965522	45965545	11	-	26780180	A375	viability (Avana lentiGuide)	CAGCTCCTCAGCTTATCCAGAGG	PHF21A	ENSG00000135365	19.1637728810135	[]	[]	8	hSpCas9	negative selection	3652404
45971242	45971265	11	+	26780180	A375	viability (Avana lentiGuide)	GATGGCGGTCACCATAGCAATGG	PHF21A	ENSG00000135365	0.872991595530842	[]	[]	1	hSpCas9	negative selection	3652405
45971303	45971326	11	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GTTGCTGCTTTCAAGACGAGAGG	PHF21A	ENSG00000135365	0.18166805297457952	[5]	[7,6]	5	hSpCas9	positive selection	3761059
45965372	45965395	11	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCATTGTGATAGCTACTCCAGGG	PHF21A	ENSG00000135365	0.06983087491473289	[5]	[5,4]	1	hSpCas9	positive selection	3761060
46076749	46076772	11	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCTTTGAGTGAGAAACAGGTAGG	PHF21A	ENSG00000135365	-0.1287255517434664	[4]	[4,2]	-2	hSpCas9	positive selection	3761061
46084195	46084218	11	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGAGTTGCAGACTCTACAGGAGG	PHF21A	ENSG00000135365	0.19814662936559588	[5]	[5,5]	5	hSpCas9	positive selection	3761062
45965522	45965545	11	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CAGCTCCTCAGCTTATCCAGAGG	PHF21A	ENSG00000135365	-0.39220736008684876	[4]	[2,2]	-5	hSpCas9	positive selection	3761063
45971242	45971265	11	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GATGGCGGTCACCATAGCAATGG	PHF21A	ENSG00000135365	0.16014091149951074	[4]	[5,4]	4	hSpCas9	positive selection	3761064
45971303	45971326	11	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GTTGCTGCTTTCAAGACGAGAGG	PHF21A	ENSG00000135365	0.2736405536597383	[6]	[6,6]	7	hSpCas9	positive selection	3869666
45965372	45965395	11	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCATTGTGATAGCTACTCCAGGG	PHF21A	ENSG00000135365	-0.09579377117464545	[5]	[4,4]	-1	hSpCas9	positive selection	3869667
46076749	46076772	11	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCTTTGAGTGAGAAACAGGTAGG	PHF21A	ENSG00000135365	-0.586233694985116	[5]	[1,3]	-6	hSpCas9	positive selection	3869668
46084195	46084218	11	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGAGTTGCAGACTCTACAGGAGG	PHF21A	ENSG00000135365	-0.27651187606017524	[3]	[2,2]	-4	hSpCas9	positive selection	3869669
45965522	45965545	11	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CAGCTCCTCAGCTTATCCAGAGG	PHF21A	ENSG00000135365	-0.9914280614041266	[4]	[0,2]	-8	hSpCas9	positive selection	3869670
45971242	45971265	11	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GATGGCGGTCACCATAGCAATGG	PHF21A	ENSG00000135365	-0.6016041737807134	[5]	[2,2]	-6	hSpCas9	positive selection	3869671
45979943	45979966	11	-	26780180	A375	viability	AAAGAGTAGTTGAACAGCTACGG	PHF21A	ENSG00000135365	1.04504786943063	[]	[]	5	hSpCas9	negative selection	3980454
46079142	46079165	11	-	26780180	A375	viability	ACTGGTTGCTCAAATGAAGCAGG	PHF21A	ENSG00000135365	1.01066651274281	[]	[]	5	hSpCas9	negative selection	3980455
46084198	46084221	11	-	26780180	A375	viability	GATGGAGTTGCAGACTCTACAGG	PHF21A	ENSG00000135365	1.46478442938144	[]	[]	8	hSpCas9	negative selection	3980456
46084174	46084197	11	-	26780180	A375	viability	GGCTCTTAAAGTGGAAATTCAGG	PHF21A	ENSG00000135365	1.36698655179455	[]	[]	7	hSpCas9	negative selection	3980457
45979893	45979916	11	+	26780180	A375	viability	GGCTGTATTTGGAACTTGTCCGG	PHF21A	ENSG00000135365	1.04771647495967	[]	[]	5	hSpCas9	negative selection	3980458
45979759	45979782	11	-	26780180	A375	viability	TCCCAACCTGACTGCTTCACAGG	PHF21A	ENSG00000135365	0.713303776765803	[]	[]	2	hSpCas9	negative selection	3980459
45979943	45979966	11	-	26780180	HT29	viability (GeCKOv2 library)	AAAGAGTAGTTGAACAGCTACGG	PHF21A	ENSG00000135365	0.749479750239708	[]	[]	3	hSpCas9	negative selection	4088420
46079142	46079165	11	-	26780180	HT29	viability (GeCKOv2 library)	ACTGGTTGCTCAAATGAAGCAGG	PHF21A	ENSG00000135365	0.923955293100503	[]	[]	4	hSpCas9	negative selection	4088421
46084198	46084221	11	-	26780180	HT29	viability (GeCKOv2 library)	GATGGAGTTGCAGACTCTACAGG	PHF21A	ENSG00000135365	0.834399838669223	[]	[]	3	hSpCas9	negative selection	4088422
46084174	46084197	11	-	26780180	HT29	viability (GeCKOv2 library)	GGCTCTTAAAGTGGAAATTCAGG	PHF21A	ENSG00000135365	1.69818186454505	[]	[]	8	hSpCas9	negative selection	4088423
45979893	45979916	11	+	26780180	HT29	viability (GeCKOv2 library)	GGCTGTATTTGGAACTTGTCCGG	PHF21A	ENSG00000135365	0.468146599429596	[]	[]	1	hSpCas9	negative selection	4088424
45979759	45979782	11	-	26780180	HT29	viability (GeCKOv2 library)	TCCCAACCTGACTGCTTCACAGG	PHF21A	ENSG00000135365	0.871476509491933	[]	[]	3	hSpCas9	negative selection	4088425
46079142	46079165	11	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	ACTGGTTGCTCAAATGAAGCAGG	PHF21A	ENSG00000135365	0.2501247636490623	[4]	[2,3]	6	hSpCas9	positive selection	4160259
46084198	46084221	11	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GATGGAGTTGCAGACTCTACAGG	PHF21A	ENSG00000135365	0.1827897432355869	[3]	[3,2]	5	hSpCas9	positive selection	4160260
46079142	46079165	11	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	ACTGGTTGCTCAAATGAAGCAGG	PHF21A	ENSG00000135365	1.9455879844155985	[2]	[4,3,2,4]	9	hSpCas9	positive selection	4224281
46084198	46084221	11	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GATGGAGTTGCAGACTCTACAGG	PHF21A	ENSG00000135365	0.7165645195424462	[4]	[1,2,2,4]	4	hSpCas9	positive selection	4224282
45979893	45979916	11	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GGCTGTATTTGGAACTTGTCCGG	PHF21A	ENSG00000135365	0.5925654389974135	[2]	[3,3]	9	hSpCas9	positive selection	4290018
46079142	46079165	11	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ACTGGTTGCTCAAATGAAGCAGG	PHF21A	ENSG00000135365	0.15901858869164742	[2]	[3,1]	3	hSpCas9	positive selection	4290019
46084198	46084221	11	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GATGGAGTTGCAGACTCTACAGG	PHF21A	ENSG00000135365	0.08038492501057054	[3]	[3,2]	1	hSpCas9	positive selection	4290020
45979759	45979782	11	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TCCCAACCTGACTGCTTCACAGG	PHF21A	ENSG00000135365	0.32342606097790294	[4]	[4,4]	6	hSpCas9	positive selection	4354270
46084174	46084197	11	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GGCTCTTAAAGTGGAAATTCAGG	PHF21A	ENSG00000135365	-0.22674303577951066	[2]	[2,0]	-4	hSpCas9	positive selection	4354271
45979943	45979966	11	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AAAGAGTAGTTGAACAGCTACGG	PHF21A	ENSG00000135365	-0.2313721095933633	[3]	[2,0]	-5	hSpCas9	positive selection	4354272
45971167	45971189	11	+	27760321	OCIAML3	viability	AGTGACCTTACTAGACGTCTGG	PHF21A	ENSG00000135365	-1.2408395290166776	[561,496]	[203,136]	-8	hSpCas9	negative selection	4427442
45971229	45971251	11	-	27760321	OCIAML3	viability	ACCGCCATCAACAGTCAGAAGG	PHF21A	ENSG00000135365	0.7010920067215389	[472,368]	[426,667]	8	hSpCas9	negative selection	4427443
45965376	45965398	11	+	27760321	OCIAML3	viability	GGAGTAGCTATCACAATGCTGG	PHF21A	ENSG00000135365	-0.048325741514843146	[481,414]	[217,494]	0	hSpCas9	negative selection	4427444
45965409	45965431	11	+	27760321	OCIAML3	viability	ATGGGGAACGTTTTGGCTATGG	PHF21A	ENSG00000135365	0.5377559935076546	[578,385]	[491,603]	6	hSpCas9	negative selection	4427445
45965442	45965464	11	-	27760321	OCIAML3	viability	ACCCCGTCCGTGTCGTCAATGG	PHF21A	ENSG00000135365	-0.027846165045221305	[1531,1233]	[893,1264]	0	hSpCas9	negative selection	4427446
45971167	45971189	11	+	27760321	OCIAML2	viability	AGTGACCTTACTAGACGTCTGG	PHF21A	ENSG00000135365	0.08630444005912175	[561,496]	[418,499]	1	hSpCas9	negative selection	4510905
45971229	45971251	11	-	27760321	OCIAML2	viability	ACCGCCATCAACAGTCAGAAGG	PHF21A	ENSG00000135365	0.5566365795990991	[472,368]	[383,646]	7	hSpCas9	negative selection	4510906
45965376	45965398	11	+	27760321	OCIAML2	viability	GGAGTAGCTATCACAATGCTGG	PHF21A	ENSG00000135365	0.08368882383425463	[481,414]	[325,458]	1	hSpCas9	negative selection	4510907
45965409	45965431	11	+	27760321	OCIAML2	viability	ATGGGGAACGTTTTGGCTATGG	PHF21A	ENSG00000135365	0.5218621447605902	[578,385]	[521,593]	7	hSpCas9	negative selection	4510908
45965442	45965464	11	-	27760321	OCIAML2	viability	ACCCCGTCCGTGTCGTCAATGG	PHF21A	ENSG00000135365	-0.14630261087501628	[1531,1233]	[880,1168]	-2	hSpCas9	negative selection	4510909
45971167	45971189	11	+	27760321	MV411	viability	AGTGACCTTACTAGACGTCTGG	PHF21A	ENSG00000135365	-2.437739594649655	[561,496]	[39,100]	-9	hSpCas9	negative selection	4594368
45971229	45971251	11	-	27760321	MV411	viability	ACCGCCATCAACAGTCAGAAGG	PHF21A	ENSG00000135365	0.7088511152728305	[472,368]	[428,483]	5	hSpCas9	negative selection	4594369
45965376	45965398	11	+	27760321	MV411	viability	GGAGTAGCTATCACAATGCTGG	PHF21A	ENSG00000135365	-0.043937642384468734	[481,414]	[129,520]	0	hSpCas9	negative selection	4594370
45965409	45965431	11	+	27760321	MV411	viability	ATGGGGAACGTTTTGGCTATGG	PHF21A	ENSG00000135365	0.470491454844537	[578,385]	[408,474]	3	hSpCas9	negative selection	4594371
45965442	45965464	11	-	27760321	MV411	viability	ACCCCGTCCGTGTCGTCAATGG	PHF21A	ENSG00000135365	0.2995842926773207	[1531,1233]	[1148,1068]	2	hSpCas9	negative selection	4594372
45971167	45971189	11	+	27760321	HL60	viability	AGTGACCTTACTAGACGTCTGG	PHF21A	ENSG00000135365	-0.48313157735460643	[561,496]	[255,364]	-5	hSpCas9	negative selection	4677831
45971229	45971251	11	-	27760321	HL60	viability	ACCGCCATCAACAGTCAGAAGG	PHF21A	ENSG00000135365	0.3830053020178112	[472,368]	[441,448]	5	hSpCas9	negative selection	4677832
45965376	45965398	11	+	27760321	HL60	viability	GGAGTAGCTATCACAATGCTGG	PHF21A	ENSG00000135365	-0.7658041280720269	[481,414]	[176,254]	-7	hSpCas9	negative selection	4677833
45965409	45965431	11	+	27760321	HL60	viability	ATGGGGAACGTTTTGGCTATGG	PHF21A	ENSG00000135365	0.38126622371395946	[578,385]	[460,554]	5	hSpCas9	negative selection	4677834
45965442	45965464	11	-	27760321	HL60	viability	ACCCCGTCCGTGTCGTCAATGG	PHF21A	ENSG00000135365	0.16904390972394823	[1531,1233]	[1465,1047]	2	hSpCas9	negative selection	4677835
45971167	45971189	11	+	27760321	HT1080	viability	AGTGACCTTACTAGACGTCTGG	PHF21A	ENSG00000135365	1.190784645734793	[496,387]	[389,415]	6	hSpCas9	negative selection	4761294
45971229	45971251	11	-	27760321	HT1080	viability	ACCGCCATCAACAGTCAGAAGG	PHF21A	ENSG00000135365	1.75919356403997	[368,287]	[505,373]	8	hSpCas9	negative selection	4761295
45965376	45965398	11	+	27760321	HT1080	viability	GGAGTAGCTATCACAATGCTGG	PHF21A	ENSG00000135365	0.9739433270943808	[414,323]	[312,262]	5	hSpCas9	negative selection	4761296
45965409	45965431	11	+	27760321	HT1080	viability	ATGGGGAACGTTTTGGCTATGG	PHF21A	ENSG00000135365	0.7262844967145488	[385,300]	[307,136]	4	hSpCas9	negative selection	4761297
45965442	45965464	11	-	27760321	HT1080	viability	ACCCCGTCCGTGTCGTCAATGG	PHF21A	ENSG00000135365	-2.5249708981517425	[1233,962]	[23,132]	-7	hSpCas9	negative selection	4761298
45971167	45971189	11	+	27760321	HT29	viability after 7 days	AGTGACCTTACTAGACGTCTGG	PHF21A	ENSG00000135365	-0.32856831557556615	[496,387]	[471,587,305]	-5	hSpCas9	negative selection	4844757
45971229	45971251	11	-	27760321	HT29	viability after 7 days	ACCGCCATCAACAGTCAGAAGG	PHF21A	ENSG00000135365	0.7722374221043262	[368,287]	[720,721,719]	9	hSpCas9	negative selection	4844758
45965376	45965398	11	+	27760321	HT29	viability after 7 days	GGAGTAGCTATCACAATGCTGG	PHF21A	ENSG00000135365	-0.5451899493455538	[414,323]	[500,229,271]	-7	hSpCas9	negative selection	4844759
45965409	45965431	11	+	27760321	HT29	viability after 7 days	ATGGGGAACGTTTTGGCTATGG	PHF21A	ENSG00000135365	0.05906497574709485	[385,300]	[586,456,356]	0	hSpCas9	negative selection	4844760
45965442	45965464	11	-	27760321	HT29	viability after 7 days	ACCCCGTCCGTGTCGTCAATGG	PHF21A	ENSG00000135365	0.17904366725436072	[1233,962]	[1738,1522,1553]	2	hSpCas9	negative selection	4844761
45971167	45971189	11	+	27760321	HT29	viability after 25 days	AGTGACCTTACTAGACGTCTGG	PHF21A	ENSG00000135365	-0.33912028081223466	[496,387]	[557,314,305]	-3	hSpCas9	negative selection	4928220
45971229	45971251	11	-	27760321	HT29	viability after 25 days	ACCGCCATCAACAGTCAGAAGG	PHF21A	ENSG00000135365	1.0874622678855224	[368,287]	[565,841,1021]	9	hSpCas9	negative selection	4928221
45965376	45965398	11	+	27760321	HT29	viability after 25 days	GGAGTAGCTATCACAATGCTGG	PHF21A	ENSG00000135365	-0.2536204125777987	[414,323]	[384,347,323]	-3	hSpCas9	negative selection	4928222
45965409	45965431	11	+	27760321	HT29	viability after 25 days	ATGGGGAACGTTTTGGCTATGG	PHF21A	ENSG00000135365	0.19758502793129923	[385,300]	[475,250,640]	2	hSpCas9	negative selection	4928223
45965442	45965464	11	-	27760321	HT29	viability after 25 days	ACCCCGTCCGTGTCGTCAATGG	PHF21A	ENSG00000135365	0.5176784178918572	[1233,962]	[1773,1668,1964]	6	hSpCas9	negative selection	4928224
45971167	45971189	11	+	27760321	HT29	viability after 22 days	AGTGACCTTACTAGACGTCTGG	PHF21A	ENSG00000135365	-0.3660238240507938	[496,387]	[320,351,520]	-4	hSpCas9	negative selection	5011683
45971229	45971251	11	-	27760321	HT29	viability after 22 days	ACCGCCATCAACAGTCAGAAGG	PHF21A	ENSG00000135365	0.7934903614808461	[368,287]	[515,647,815]	8	hSpCas9	negative selection	5011684
45965376	45965398	11	+	27760321	HT29	viability after 22 days	GGAGTAGCTATCACAATGCTGG	PHF21A	ENSG00000135365	-0.06576234674311215	[414,323]	[292,473,460]	0	hSpCas9	negative selection	5011685
45965409	45965431	11	+	27760321	HT29	viability after 22 days	ATGGGGAACGTTTTGGCTATGG	PHF21A	ENSG00000135365	0.5324672234762471	[385,300]	[774,427,513]	6	hSpCas9	negative selection	5011686
45965442	45965464	11	-	27760321	HT29	viability after 22 days	ACCCCGTCCGTGTCGTCAATGG	PHF21A	ENSG00000135365	0.500725636565241	[1233,962]	[1983,1537,1863]	5	hSpCas9	negative selection	5011687
45971167	45971189	11	+	27760321	HT29	viability after 19 days	AGTGACCTTACTAGACGTCTGG	PHF21A	ENSG00000135365	-0.24001325356246678	[496,387]	[487,441,363]	-2	hSpCas9	negative selection	5095146
45971229	45971251	11	-	27760321	HT29	viability after 19 days	ACCGCCATCAACAGTCAGAAGG	PHF21A	ENSG00000135365	0.6919318186715687	[368,287]	[472,663,666]	7	hSpCas9	negative selection	5095147
45965376	45965398	11	+	27760321	HT29	viability after 19 days	GGAGTAGCTATCACAATGCTGG	PHF21A	ENSG00000135365	0.2981305212916291	[414,323]	[500,548,506]	3	hSpCas9	negative selection	5095148
45965409	45965431	11	+	27760321	HT29	viability after 19 days	ATGGGGAACGTTTTGGCTATGG	PHF21A	ENSG00000135365	0.9306470591597807	[385,300]	[652,516,1053]	8	hSpCas9	negative selection	5095149
45965442	45965464	11	-	27760321	HT29	viability after 19 days	ACCCCGTCCGTGTCGTCAATGG	PHF21A	ENSG00000135365	0.5966409358248814	[1233,962]	[1866,2043,1787]	6	hSpCas9	negative selection	5095150
45971167	45971189	11	+	27760321	HT29	viability after 16 days	AGTGACCTTACTAGACGTCTGG	PHF21A	ENSG00000135365	-1.0921550163538578	[496,387]	[422,103,190]	-7	hSpCas9	negative selection	5178609
45971229	45971251	11	-	27760321	HT29	viability after 16 days	ACCGCCATCAACAGTCAGAAGG	PHF21A	ENSG00000135365	0.9820051782725063	[368,287]	[685,493,999]	9	hSpCas9	negative selection	5178610
45965376	45965398	11	+	27760321	HT29	viability after 16 days	GGAGTAGCTATCACAATGCTGG	PHF21A	ENSG00000135365	0.031200208312502233	[414,323]	[386,380,496]	0	hSpCas9	negative selection	5178611
45965409	45965431	11	+	27760321	HT29	viability after 16 days	ATGGGGAACGTTTTGGCTATGG	PHF21A	ENSG00000135365	0.20584302195874404	[385,300]	[509,477,346]	2	hSpCas9	negative selection	5178612
45965442	45965464	11	-	27760321	HT29	viability after 16 days	ACCCCGTCCGTGTCGTCAATGG	PHF21A	ENSG00000135365	0.31891972048100925	[1233,962]	[1925,1150,1568]	3	hSpCas9	negative selection	5178613
45971167	45971189	11	+	27760321	HT29	viability after 13 days	AGTGACCTTACTAGACGTCTGG	PHF21A	ENSG00000135365	-0.6269648348069345	[496,387]	[276,177,529]	-6	hSpCas9	negative selection	5262072
45971229	45971251	11	-	27760321	HT29	viability after 13 days	ACCGCCATCAACAGTCAGAAGG	PHF21A	ENSG00000135365	1.045072486060035	[368,287]	[929,545,876]	9	hSpCas9	negative selection	5262073
45965376	45965398	11	+	27760321	HT29	viability after 13 days	GGAGTAGCTATCACAATGCTGG	PHF21A	ENSG00000135365	0.24479292339475572	[414,323]	[836,195,490]	3	hSpCas9	negative selection	5262074
45965409	45965431	11	+	27760321	HT29	viability after 13 days	ATGGGGAACGTTTTGGCTATGG	PHF21A	ENSG00000135365	0.5043979577311702	[385,300]	[628,543,524]	6	hSpCas9	negative selection	5262075
45965442	45965464	11	-	27760321	HT29	viability after 13 days	ACCCCGTCCGTGTCGTCAATGG	PHF21A	ENSG00000135365	0.38681907102303925	[1233,962]	[1530,1839,1629]	5	hSpCas9	negative selection	5262076
45971167	45971189	11	+	27760321	HT29	viability after 10 days	AGTGACCTTACTAGACGTCTGG	PHF21A	ENSG00000135365	-0.4462368986691597	[496,387]	[508,289,413]	-5	hSpCas9	negative selection	5345535
45971229	45971251	11	-	27760321	HT29	viability after 10 days	ACCGCCATCAACAGTCAGAAGG	PHF21A	ENSG00000135365	1.1467191208075602	[368,287]	[949,664,1097]	9	hSpCas9	negative selection	5345536
45965376	45965398	11	+	27760321	HT29	viability after 10 days	GGAGTAGCTATCACAATGCTGG	PHF21A	ENSG00000135365	-0.0656965334477351	[414,323]	[736,320,264]	-1	hSpCas9	negative selection	5345537
45965409	45965431	11	+	27760321	HT29	viability after 10 days	ATGGGGAACGTTTTGGCTATGG	PHF21A	ENSG00000135365	0.6236123461228368	[385,300]	[713,593,671]	8	hSpCas9	negative selection	5345538
45965442	45965464	11	-	27760321	HT29	viability after 10 days	ACCCCGTCCGTGTCGTCAATGG	PHF21A	ENSG00000135365	0.24599440814574813	[1233,962]	[2017,1405,1452]	3	hSpCas9	negative selection	5345539
45971167	45971189	11	+	27760321	MOLM13	viability	AGTGACCTTACTAGACGTCTGG	PHF21A	ENSG00000135365	-0.20419314262791816	[561,496]	[327,199]	-1	hSpCas9	negative selection	5428998
45971229	45971251	11	-	27760321	MOLM13	viability	ACCGCCATCAACAGTCAGAAGG	PHF21A	ENSG00000135365	-0.3582979476840348	[472,368]	[250,126]	-2	hSpCas9	negative selection	5428999
45965376	45965398	11	+	27760321	MOLM13	viability	GGAGTAGCTATCACAATGCTGG	PHF21A	ENSG00000135365	-0.6919683180267677	[481,414]	[193,123]	-4	hSpCas9	negative selection	5429000
45965409	45965431	11	+	27760321	MOLM13	viability	ATGGGGAACGTTTTGGCTATGG	PHF21A	ENSG00000135365	0.8419656006083783	[578,385]	[379,567]	6	hSpCas9	negative selection	5429001
45965442	45965464	11	-	27760321	MOLM13	viability	ACCCCGTCCGTGTCGTCAATGG	PHF21A	ENSG00000135365	-0.39638491980571744	[1531,1233]	[689,503]	-3	hSpCas9	negative selection	5429002
45979893	45979916	11	+	27260156	BXPC3	viability	GGCTGTATTTGGAACTTGTCCGG	PHF21A	ENSG00000135365	0.31043670760195674	[333]	[413,398,440,485]	6	hSpCas9	negative selection	5562478
46079142	46079165	11	-	27260156	BXPC3	viability	ACTGGTTGCTCAAATGAAGCAGG	PHF21A	ENSG00000135365	-0.13985242555551305	[452]	[480,310,440,492]	-3	hSpCas9	negative selection	5562479
46084198	46084221	11	-	27260156	BXPC3	viability	GATGGAGTTGCAGACTCTACAGG	PHF21A	ENSG00000135365	0.11905845443678564	[725]	[634,916,823,945]	2	hSpCas9	negative selection	5562480
45979759	45979782	11	-	27260156	BXPC3	viability	TCCCAACCTGACTGCTTCACAGG	PHF21A	ENSG00000135365	-0.04277470421429874	[1713]	[1634,1712,1808,1812]	-1	hSpCas9	negative selection	5626730
46084174	46084197	11	-	27260156	BXPC3	viability	GGCTCTTAAAGTGGAAATTCAGG	PHF21A	ENSG00000135365	-0.6727214029635107	[199]	[126,138,90,170]	-8	hSpCas9	negative selection	5626731
45979943	45979966	11	-	27260156	BXPC3	viability	AAAGAGTAGTTGAACAGCTACGG	PHF21A	ENSG00000135365	-0.20525209891793722	[474]	[367,417,414,539]	-5	hSpCas9	negative selection	5626732
45979893	45979916	11	+	27260156	A673	viability	GGCTGTATTTGGAACTTGTCCGG	PHF21A	ENSG00000135365	0.22300775325578437	[333]	[434,538,454,434]	5	hSpCas9	negative selection	5683729
46079142	46079165	11	-	27260156	A673	viability	ACTGGTTGCTCAAATGAAGCAGG	PHF21A	ENSG00000135365	-0.28989987402314277	[452]	[569,487,311,421]	-6	hSpCas9	negative selection	5683730
46084198	46084221	11	-	27260156	A673	viability	GATGGAGTTGCAGACTCTACAGG	PHF21A	ENSG00000135365	0.10568293833973585	[725]	[1162,801,849,966]	2	hSpCas9	negative selection	5683731
45979759	45979782	11	-	27260156	A673	viability	TCCCAACCTGACTGCTTCACAGG	PHF21A	ENSG00000135365	-0.02462992013483567	[1713]	[2092,2034,1861,2112]	0	hSpCas9	negative selection	5747981
46084174	46084197	11	-	27260156	A673	viability	GGCTCTTAAAGTGGAAATTCAGG	PHF21A	ENSG00000135365	-0.7255747059699118	[199]	[197,135,126,124]	-9	hSpCas9	negative selection	5747982
45979943	45979966	11	-	27260156	A673	viability	AAAGAGTAGTTGAACAGCTACGG	PHF21A	ENSG00000135365	-0.2915668340155266	[474]	[479,443,461,479]	-6	hSpCas9	negative selection	5747983
45979893	45979916	11	+	27260156	A375	viability	GGCTGTATTTGGAACTTGTCCGG	PHF21A	ENSG00000135365	1.0488807443809658	[333]	[787,1001,726,742]	9	hSpCas9	negative selection	5804980
46079142	46079165	11	-	27260156	A375	viability	ACTGGTTGCTCAAATGAAGCAGG	PHF21A	ENSG00000135365	0.1486409848815491	[452]	[707,853,363,469]	2	hSpCas9	negative selection	5804981
46084198	46084221	11	-	27260156	A375	viability	GATGGAGTTGCAGACTCTACAGG	PHF21A	ENSG00000135365	0.09985572027987566	[725]	[752,1001,1069,827]	1	hSpCas9	negative selection	5804982
45979759	45979782	11	-	27260156	A375	viability	TCCCAACCTGACTGCTTCACAGG	PHF21A	ENSG00000135365	-0.00543537493639068	[1713]	[1955,2248,2073,1754]	0	hSpCas9	negative selection	5869232
46084174	46084197	11	-	27260156	A375	viability	GGCTCTTAAAGTGGAAATTCAGG	PHF21A	ENSG00000135365	-0.3748234079463608	[199]	[247,267,113,110]	-5	hSpCas9	negative selection	5869233
45979943	45979966	11	-	27260156	A375	viability	AAAGAGTAGTTGAACAGCTACGG	PHF21A	ENSG00000135365	-0.4254859343608225	[474]	[446,396,439,369]	-5	hSpCas9	negative selection	5869234
45979893	45979916	11	+	27260156	COLO741	viability	GGCTGTATTTGGAACTTGTCCGG	PHF21A	ENSG00000135365	0.5757457141006244	[333]	[784,552,584]	9	hSpCas9	negative selection	5926231
46079142	46079165	11	-	27260156	COLO741	viability	ACTGGTTGCTCAAATGAAGCAGG	PHF21A	ENSG00000135365	0.016363845103742863	[452]	[753,570,453]	0	hSpCas9	negative selection	5926232
46084198	46084221	11	-	27260156	COLO741	viability	GATGGAGTTGCAGACTCTACAGG	PHF21A	ENSG00000135365	0.22276717251374556	[725]	[1127,789,1312]	5	hSpCas9	negative selection	5926233
45979759	45979782	11	-	27260156	COLO741	viability	TCCCAACCTGACTGCTTCACAGG	PHF21A	ENSG00000135365	-0.031112756542169606	[1713]	[2216,2208,2014]	0	hSpCas9	negative selection	5990483
46084174	46084197	11	-	27260156	COLO741	viability	GGCTCTTAAAGTGGAAATTCAGG	PHF21A	ENSG00000135365	-0.8972454507229544	[199]	[111,156,139]	-9	hSpCas9	negative selection	5990484
45979943	45979966	11	-	27260156	COLO741	viability	AAAGAGTAGTTGAACAGCTACGG	PHF21A	ENSG00000135365	-0.26494812889804525	[474]	[703,396,434]	-5	hSpCas9	negative selection	5990485
45979893	45979916	11	+	27260156	CAL120	viability	GGCTGTATTTGGAACTTGTCCGG	PHF21A	ENSG00000135365	0.5829125969760595	[333]	[734,508,639]	8	hSpCas9	negative selection	6047482
46079142	46079165	11	-	27260156	CAL120	viability	ACTGGTTGCTCAAATGAAGCAGG	PHF21A	ENSG00000135365	0.2950035842576158	[452]	[800,598,690]	4	hSpCas9	negative selection	6047483
46084198	46084221	11	-	27260156	CAL120	viability	GATGGAGTTGCAGACTCTACAGG	PHF21A	ENSG00000135365	0.14122568563686555	[725]	[1252,933,842]	2	hSpCas9	negative selection	6047484
45979759	45979782	11	-	27260156	CAL120	viability	TCCCAACCTGACTGCTTCACAGG	PHF21A	ENSG00000135365	-0.05048147788118329	[1713]	[2740,1798,1745]	0	hSpCas9	negative selection	6111734
46084174	46084197	11	-	27260156	CAL120	viability	GGCTCTTAAAGTGGAAATTCAGG	PHF21A	ENSG00000135365	-0.4235608892245408	[199]	[69,159,306]	-6	hSpCas9	negative selection	6111735
45979943	45979966	11	-	27260156	CAL120	viability	AAAGAGTAGTTGAACAGCTACGG	PHF21A	ENSG00000135365	-0.2374951995966135	[474]	[702,316,513]	-3	hSpCas9	negative selection	6111736
45979893	45979916	11	+	27260156	CADOES1	viability	GGCTGTATTTGGAACTTGTCCGG	PHF21A	ENSG00000135365	0.49356336783691523	[333]	[298,373,526,553]	7	hSpCas9	negative selection	6168733
46079142	46079165	11	-	27260156	CADOES1	viability	ACTGGTTGCTCAAATGAAGCAGG	PHF21A	ENSG00000135365	-0.19818559922784076	[452]	[412,321,359,373]	-3	hSpCas9	negative selection	6168734
46084198	46084221	11	-	27260156	CADOES1	viability	GATGGAGTTGCAGACTCTACAGG	PHF21A	ENSG00000135365	0.3969913129478526	[725]	[1238,773,661,879]	6	hSpCas9	negative selection	6168735
45979759	45979782	11	-	27260156	CADOES1	viability	TCCCAACCTGACTGCTTCACAGG	PHF21A	ENSG00000135365	0.08969642673245071	[1713]	[2070,1584,1619,1500]	1	hSpCas9	negative selection	6232985
46084174	46084197	11	-	27260156	CADOES1	viability	GGCTCTTAAAGTGGAAATTCAGG	PHF21A	ENSG00000135365	-0.8020721820068997	[199]	[53,33,172,167]	-8	hSpCas9	negative selection	6232986
45979943	45979966	11	-	27260156	CADOES1	viability	AAAGAGTAGTTGAACAGCTACGG	PHF21A	ENSG00000135365	-0.6276324920059578	[474]	[170,257,452,260]	-8	hSpCas9	negative selection	6232987
45979893	45979916	11	+	27260156	EWS502	viability	GGCTGTATTTGGAACTTGTCCGG	PHF21A	ENSG00000135365	0.46767390064215014	[333]	[423,426,551,568]	7	hSpCas9	negative selection	6289984
46079142	46079165	11	-	27260156	EWS502	viability	ACTGGTTGCTCAAATGAAGCAGG	PHF21A	ENSG00000135365	0.17721225810774993	[452]	[442,422,782,538]	3	hSpCas9	negative selection	6289985
46084198	46084221	11	-	27260156	EWS502	viability	GATGGAGTTGCAGACTCTACAGG	PHF21A	ENSG00000135365	-0.15150938156394905	[725]	[511,855,691,723]	-3	hSpCas9	negative selection	6289986
45979759	45979782	11	-	27260156	EWS502	viability	TCCCAACCTGACTGCTTCACAGG	PHF21A	ENSG00000135365	0.06259211082822924	[1713]	[1962,1995,1601,2006]	1	hSpCas9	negative selection	6354236
46084174	46084197	11	-	27260156	EWS502	viability	GGCTCTTAAAGTGGAAATTCAGG	PHF21A	ENSG00000135365	-0.44425596401043577	[199]	[268,145,86,101]	-6	hSpCas9	negative selection	6354237
45979943	45979966	11	-	27260156	EWS502	viability	AAAGAGTAGTTGAACAGCTACGG	PHF21A	ENSG00000135365	-0.191876100263893	[474]	[414,360,486,508]	-3	hSpCas9	negative selection	6354238
45979893	45979916	11	+	27260156	EW8	viability	GGCTGTATTTGGAACTTGTCCGG	PHF21A	ENSG00000135365	0.5641620361495561	[333]	[395,544,251,431]	8	hSpCas9	negative selection	6411235
46079142	46079165	11	-	27260156	EW8	viability	ACTGGTTGCTCAAATGAAGCAGG	PHF21A	ENSG00000135365	0.10412599570098874	[452]	[560,250,351,437]	2	hSpCas9	negative selection	6411236
46084198	46084221	11	-	27260156	EW8	viability	GATGGAGTTGCAGACTCTACAGG	PHF21A	ENSG00000135365	0.11591218683652127	[725]	[719,653,630,553]	2	hSpCas9	negative selection	6411237
45979759	45979782	11	-	27260156	EW8	viability	TCCCAACCTGACTGCTTCACAGG	PHF21A	ENSG00000135365	-0.06021688968815897	[1713]	[1542,1330,1265,1219]	-1	hSpCas9	negative selection	6475487
46084174	46084197	11	-	27260156	EW8	viability	GGCTCTTAAAGTGGAAATTCAGG	PHF21A	ENSG00000135365	0.01811767941358844	[199]	[144,326,86,108]	0	hSpCas9	negative selection	6475488
45979943	45979966	11	-	27260156	EW8	viability	AAAGAGTAGTTGAACAGCTACGG	PHF21A	ENSG00000135365	-0.6312777242415989	[474]	[323,229,168,291]	-8	hSpCas9	negative selection	6475489
45979893	45979916	11	+	27260156	CORL105	viability	GGCTGTATTTGGAACTTGTCCGG	PHF21A	ENSG00000135365	0.1412549037125383	[333]	[481,267,510,480]	2	hSpCas9	negative selection	6532486
46079142	46079165	11	-	27260156	CORL105	viability	ACTGGTTGCTCAAATGAAGCAGG	PHF21A	ENSG00000135365	-0.21182408751871415	[452]	[489,411,542,401]	-4	hSpCas9	negative selection	6532487
46084198	46084221	11	-	27260156	CORL105	viability	GATGGAGTTGCAGACTCTACAGG	PHF21A	ENSG00000135365	-0.1743944665322495	[725]	[688,696,929,722]	-3	hSpCas9	negative selection	6532488
45979759	45979782	11	-	27260156	CORL105	viability	TCCCAACCTGACTGCTTCACAGG	PHF21A	ENSG00000135365	-0.1178309141814331	[1713]	[1604,1814,2247,1782]	-2	hSpCas9	negative selection	6596738
46084174	46084197	11	-	27260156	CORL105	viability	GGCTCTTAAAGTGGAAATTCAGG	PHF21A	ENSG00000135365	-0.5719525031635091	[199]	[160,186,215,74]	-8	hSpCas9	negative selection	6596739
45979943	45979966	11	-	27260156	CORL105	viability	AAAGAGTAGTTGAACAGCTACGG	PHF21A	ENSG00000135365	-0.25816348827433544	[474]	[513,395,410,532]	-5	hSpCas9	negative selection	6596740
45979893	45979916	11	+	27260156	HS294T	viability	GGCTGTATTTGGAACTTGTCCGG	PHF21A	ENSG00000135365	0.9772456535200003	[333]	[441,159,144,253]	9	hSpCas9	negative selection	6653737
46079142	46079165	11	-	27260156	HS294T	viability	ACTGGTTGCTCAAATGAAGCAGG	PHF21A	ENSG00000135365	0.24143207570259093	[452]	[129,338,191,161]	3	hSpCas9	negative selection	6653738
46084198	46084221	11	-	27260156	HS294T	viability	GATGGAGTTGCAGACTCTACAGG	PHF21A	ENSG00000135365	0.5832551257155087	[725]	[364,381,317,662]	7	hSpCas9	negative selection	6653739
45979759	45979782	11	-	27260156	HS294T	viability	TCCCAACCTGACTGCTTCACAGG	PHF21A	ENSG00000135365	0.1285052351387903	[1713]	[630,799,590,910]	1	hSpCas9	negative selection	6717989
46084174	46084197	11	-	27260156	HS294T	viability	GGCTCTTAAAGTGGAAATTCAGG	PHF21A	ENSG00000135365	-0.945316391969075	[199]	[38,32,42,46]	-8	hSpCas9	negative selection	6717990
45979943	45979966	11	-	27260156	HS294T	viability	AAAGAGTAGTTGAACAGCTACGG	PHF21A	ENSG00000135365	0.3489118552682796	[474]	[123,303,326,178]	5	hSpCas9	negative selection	6717991
45979893	45979916	11	+	27260156	HCC44	viability	GGCTGTATTTGGAACTTGTCCGG	PHF21A	ENSG00000135365	0.5578977561176549	[333]	[533,422,734,574]	8	hSpCas9	negative selection	6774988
46079142	46079165	11	-	27260156	HCC44	viability	ACTGGTTGCTCAAATGAAGCAGG	PHF21A	ENSG00000135365	0.24029207840509395	[452]	[721,737,534,406]	4	hSpCas9	negative selection	6774989
46084198	46084221	11	-	27260156	HCC44	viability	GATGGAGTTGCAGACTCTACAGG	PHF21A	ENSG00000135365	0.2894102594449044	[725]	[1171,914,974,967]	5	hSpCas9	negative selection	6774990
45979759	45979782	11	-	27260156	HCC44	viability	TCCCAACCTGACTGCTTCACAGG	PHF21A	ENSG00000135365	-0.021798217133254694	[1713]	[2064,1360,2228,2107]	0	hSpCas9	negative selection	6839240
46084174	46084197	11	-	27260156	HCC44	viability	GGCTCTTAAAGTGGAAATTCAGG	PHF21A	ENSG00000135365	-0.5037386978766567	[199]	[136,168,193,139]	-6	hSpCas9	negative selection	6839241
45979943	45979966	11	-	27260156	HCC44	viability	AAAGAGTAGTTGAACAGCTACGG	PHF21A	ENSG00000135365	0.08689489160254969	[474]	[448,734,777,324]	1	hSpCas9	negative selection	6839242
45979893	45979916	11	+	27260156	G402	viability	GGCTGTATTTGGAACTTGTCCGG	PHF21A	ENSG00000135365	0.7679515124275977	[333]	[1171,673,488,514]	8	hSpCas9	negative selection	6896239
46079142	46079165	11	-	27260156	G402	viability	ACTGGTTGCTCAAATGAAGCAGG	PHF21A	ENSG00000135365	-0.5062589690494413	[452]	[462,378,477,251]	-6	hSpCas9	negative selection	6896240
46084198	46084221	11	-	27260156	G402	viability	GATGGAGTTGCAGACTCTACAGG	PHF21A	ENSG00000135365	0.168072689157872	[725]	[797,1207,1165,798]	2	hSpCas9	negative selection	6896241
45979759	45979782	11	-	27260156	G402	viability	TCCCAACCTGACTGCTTCACAGG	PHF21A	ENSG00000135365	0.12866367194214923	[1713]	[3089,1896,2580,1691]	1	hSpCas9	negative selection	6960491
46084174	46084197	11	-	27260156	G402	viability	GGCTCTTAAAGTGGAAATTCAGG	PHF21A	ENSG00000135365	-1.2523077744616997	[199]	[73,118,105,106]	-8	hSpCas9	negative selection	6960492
45979943	45979966	11	-	27260156	G402	viability	AAAGAGTAGTTGAACAGCTACGG	PHF21A	ENSG00000135365	-0.1801713963341622	[474]	[254,850,559,367]	-2	hSpCas9	negative selection	6960493
45979893	45979916	11	+	27260156	L33	viability	GGCTGTATTTGGAACTTGTCCGG	PHF21A	ENSG00000135365	0.27997191846701097	[333]	[363,201,259,352]	6	hSpCas9	negative selection	7017490
46079142	46079165	11	-	27260156	L33	viability	ACTGGTTGCTCAAATGAAGCAGG	PHF21A	ENSG00000135365	-0.1380662175064584	[452]	[429,156,277,390]	-3	hSpCas9	negative selection	7017491
46084198	46084221	11	-	27260156	L33	viability	GATGGAGTTGCAGACTCTACAGG	PHF21A	ENSG00000135365	0.19345232564624582	[725]	[847,284,565,875]	4	hSpCas9	negative selection	7017492
45979759	45979782	11	-	27260156	L33	viability	TCCCAACCTGACTGCTTCACAGG	PHF21A	ENSG00000135365	-0.09022199381197882	[1713]	[1580,693,961,1634]	-2	hSpCas9	negative selection	7081742
46084174	46084197	11	-	27260156	L33	viability	GGCTCTTAAAGTGGAAATTCAGG	PHF21A	ENSG00000135365	-0.7769678531028616	[199]	[111,69,64,80]	-9	hSpCas9	negative selection	7081743
45979943	45979966	11	-	27260156	L33	viability	AAAGAGTAGTTGAACAGCTACGG	PHF21A	ENSG00000135365	-0.1573653159027327	[474]	[355,177,237,534]	-4	hSpCas9	negative selection	7081744
45979893	45979916	11	+	27260156	K562	viability	GGCTGTATTTGGAACTTGTCCGG	PHF21A	ENSG00000135365	0.5845339127187943	[333]	[640,513,330,323]	7	hSpCas9	negative selection	7138741
46079142	46079165	11	-	27260156	K562	viability	ACTGGTTGCTCAAATGAAGCAGG	PHF21A	ENSG00000135365	0.33960127818917785	[452]	[435,552,785,280]	4	hSpCas9	negative selection	7138742
46084198	46084221	11	-	27260156	K562	viability	GATGGAGTTGCAGACTCTACAGG	PHF21A	ENSG00000135365	0.19649676944520822	[725]	[742,748,928,551]	2	hSpCas9	negative selection	7138743
45979759	45979782	11	-	27260156	K562	viability	TCCCAACCTGACTGCTTCACAGG	PHF21A	ENSG00000135365	-0.3375350586126995	[1713]	[1759,1249,843,1024]	-4	hSpCas9	negative selection	7202993
46084174	46084197	11	-	27260156	K562	viability	GGCTCTTAAAGTGGAAATTCAGG	PHF21A	ENSG00000135365	-1.1070776344390114	[199]	[52,73,169,34]	-8	hSpCas9	negative selection	7202994
45979943	45979966	11	-	27260156	K562	viability	AAAGAGTAGTTGAACAGCTACGG	PHF21A	ENSG00000135365	-0.7114408351376267	[474]	[179,218,266,343]	-7	hSpCas9	negative selection	7202995
45979893	45979916	11	+	27260156	HT29	viability	GGCTGTATTTGGAACTTGTCCGG	PHF21A	ENSG00000135365	0.5554280566461265	[333]	[657,662,548,530]	9	hSpCas9	negative selection	7259992
46079142	46079165	11	-	27260156	HT29	viability	ACTGGTTGCTCAAATGAAGCAGG	PHF21A	ENSG00000135365	0.23555898285118343	[452]	[709,680,662,553]	4	hSpCas9	negative selection	7259993
46084198	46084221	11	-	27260156	HT29	viability	GATGGAGTTGCAGACTCTACAGG	PHF21A	ENSG00000135365	0.4441366958964297	[725]	[1412,1386,1181,883]	8	hSpCas9	negative selection	7259994
45979759	45979782	11	-	27260156	HT29	viability	TCCCAACCTGACTGCTTCACAGG	PHF21A	ENSG00000135365	0.15596088117636708	[1713]	[2644,2525,2265,1923]	3	hSpCas9	negative selection	7324244
46084174	46084197	11	-	27260156	HT29	viability	GGCTCTTAAAGTGGAAATTCAGG	PHF21A	ENSG00000135365	-0.6358506478993147	[199]	[123,184,215,105]	-8	hSpCas9	negative selection	7324245
45979943	45979966	11	-	27260156	HT29	viability	AAAGAGTAGTTGAACAGCTACGG	PHF21A	ENSG00000135365	0.23850074341336935	[474]	[662,804,578,681]	4	hSpCas9	negative selection	7324246
45979893	45979916	11	+	27260156	MHHES1	viability	GGCTGTATTTGGAACTTGTCCGG	PHF21A	ENSG00000135365	0.5092303934702209	[333]	[692,702,392,405]	8	hSpCas9	negative selection	7381243
46079142	46079165	11	-	27260156	MHHES1	viability	ACTGGTTGCTCAAATGAAGCAGG	PHF21A	ENSG00000135365	-0.3678972684136987	[452]	[370,551,299,367]	-6	hSpCas9	negative selection	7381244
46084198	46084221	11	-	27260156	MHHES1	viability	GATGGAGTTGCAGACTCTACAGG	PHF21A	ENSG00000135365	0.03932020844458295	[725]	[800,1137,918,572]	0	hSpCas9	negative selection	7381245
45979759	45979782	11	-	27260156	MHHES1	viability	TCCCAACCTGACTGCTTCACAGG	PHF21A	ENSG00000135365	0.1104502586952727	[1713]	[1940,2361,2354,1726]	2	hSpCas9	negative selection	7445495
46084174	46084197	11	-	27260156	MHHES1	viability	GGCTCTTAAAGTGGAAATTCAGG	PHF21A	ENSG00000135365	-0.7468829153133945	[199]	[129,113,110,167]	-8	hSpCas9	negative selection	7445496
45979943	45979966	11	-	27260156	MHHES1	viability	AAAGAGTAGTTGAACAGCTACGG	PHF21A	ENSG00000135365	-0.3865590779235298	[474]	[414,469,532,253]	-6	hSpCas9	negative selection	7445497
45979893	45979916	11	+	27260156	MEWO	viability	GGCTGTATTTGGAACTTGTCCGG	PHF21A	ENSG00000135365	0.435692847939401	[333]	[475,458,342]	8	hSpCas9	negative selection	7502494
46079142	46079165	11	-	27260156	MEWO	viability	ACTGGTTGCTCAAATGAAGCAGG	PHF21A	ENSG00000135365	-0.1346893753424601	[452]	[504,398,276]	-3	hSpCas9	negative selection	7502495
46084198	46084221	11	-	27260156	MEWO	viability	GATGGAGTTGCAGACTCTACAGG	PHF21A	ENSG00000135365	0.26400015647760855	[725]	[1028,811,646]	6	hSpCas9	negative selection	7502496
45979759	45979782	11	-	27260156	MEWO	viability	TCCCAACCTGACTGCTTCACAGG	PHF21A	ENSG00000135365	0.04313684814783669	[1713]	[1744,1913,1313]	1	hSpCas9	negative selection	7566746
46084174	46084197	11	-	27260156	MEWO	viability	GGCTCTTAAAGTGGAAATTCAGG	PHF21A	ENSG00000135365	-0.6653776908373912	[199]	[143,107,106]	-8	hSpCas9	negative selection	7566747
45979943	45979966	11	-	27260156	MEWO	viability	AAAGAGTAGTTGAACAGCTACGG	PHF21A	ENSG00000135365	-0.2032258199964778	[474]	[467,345,359]	-4	hSpCas9	negative selection	7566748
45979893	45979916	11	+	27260156	LNCAPCLONEFGC	viability	GGCTGTATTTGGAACTTGTCCGG	PHF21A	ENSG00000135365	0.6337553862045898	[333]	[479,418,606,394]	8	hSpCas9	negative selection	7623745
46079142	46079165	11	-	27260156	LNCAPCLONEFGC	viability	ACTGGTTGCTCAAATGAAGCAGG	PHF21A	ENSG00000135365	0.06454297289644102	[452]	[603,351,395,360]	1	hSpCas9	negative selection	7623746
46084198	46084221	11	-	27260156	LNCAPCLONEFGC	viability	GATGGAGTTGCAGACTCTACAGG	PHF21A	ENSG00000135365	-0.17455346833024388	[725]	[534,608,618,571]	-3	hSpCas9	negative selection	7623747
45979759	45979782	11	-	27260156	LNCAPCLONEFGC	viability	TCCCAACCTGACTGCTTCACAGG	PHF21A	ENSG00000135365	-0.031455111142225434	[1713]	[1325,1361,1884,1570]	0	hSpCas9	negative selection	7687997
46084174	46084197	11	-	27260156	LNCAPCLONEFGC	viability	GGCTCTTAAAGTGGAAATTCAGG	PHF21A	ENSG00000135365	-0.5499389754907003	[199]	[81,179,116,111]	-7	hSpCas9	negative selection	7687998
45979943	45979966	11	-	27260156	LNCAPCLONEFGC	viability	AAAGAGTAGTTGAACAGCTACGG	PHF21A	ENSG00000135365	-0.3802364735077701	[474]	[250,326,411,345]	-5	hSpCas9	negative selection	7687999
45979893	45979916	11	+	27260156	PANC0327	viability	GGCTGTATTTGGAACTTGTCCGG	PHF21A	ENSG00000135365	0.8071896084065525	[333]	[634,296,708,473]	9	hSpCas9	negative selection	7744996
46079142	46079165	11	-	27260156	PANC0327	viability	ACTGGTTGCTCAAATGAAGCAGG	PHF21A	ENSG00000135365	-0.050083609235059674	[452]	[285,402,279,574]	0	hSpCas9	negative selection	7744997
46084198	46084221	11	-	27260156	PANC0327	viability	GATGGAGTTGCAGACTCTACAGG	PHF21A	ENSG00000135365	-0.036140742747034604	[725]	[804,575,638,516]	0	hSpCas9	negative selection	7744998
45979759	45979782	11	-	27260156	PANC0327	viability	TCCCAACCTGACTGCTTCACAGG	PHF21A	ENSG00000135365	0.0827695067265819	[1713]	[1474,1481,2134,1363]	1	hSpCas9	negative selection	7809248
46084174	46084197	11	-	27260156	PANC0327	viability	GGCTCTTAAAGTGGAAATTCAGG	PHF21A	ENSG00000135365	-0.009167031401838832	[199]	[81,279,174,147]	0	hSpCas9	negative selection	7809249
45979943	45979966	11	-	27260156	PANC0327	viability	AAAGAGTAGTTGAACAGCTACGG	PHF21A	ENSG00000135365	0.25930473727426556	[474]	[506,846,405,215]	4	hSpCas9	negative selection	7809250
45979893	45979916	11	+	27260156	NCIH2009	viability	GGCTGTATTTGGAACTTGTCCGG	PHF21A	ENSG00000135365	0.09930248395900765	[333]	[685,424,425]	1	hSpCas9	negative selection	7866247
46079142	46079165	11	-	27260156	NCIH2009	viability	ACTGGTTGCTCAAATGAAGCAGG	PHF21A	ENSG00000135365	-0.027087380126036655	[452]	[755,456,678]	0	hSpCas9	negative selection	7866248
46084198	46084221	11	-	27260156	NCIH2009	viability	GATGGAGTTGCAGACTCTACAGG	PHF21A	ENSG00000135365	-0.26659387606482726	[725]	[741,961,801]	-4	hSpCas9	negative selection	7866249
45979759	45979782	11	-	27260156	NCIH2009	viability	TCCCAACCTGACTGCTTCACAGG	PHF21A	ENSG00000135365	-0.07302152036303533	[1713]	[2749,2073,2098]	-1	hSpCas9	negative selection	7930499
46084174	46084197	11	-	27260156	NCIH2009	viability	GGCTCTTAAAGTGGAAATTCAGG	PHF21A	ENSG00000135365	-0.840541722708847	[199]	[226,94,160]	-7	hSpCas9	negative selection	7930500
45979943	45979966	11	-	27260156	NCIH2009	viability	AAAGAGTAGTTGAACAGCTACGG	PHF21A	ENSG00000135365	-0.394042587184081	[474]	[712,358,485]	-5	hSpCas9	negative selection	7930501
45979893	45979916	11	+	27260156	NCIH1373	viability	GGCTGTATTTGGAACTTGTCCGG	PHF21A	ENSG00000135365	0.87322023822744	[333]	[529,641,921,161]	8	hSpCas9	negative selection	7987498
46079142	46079165	11	-	27260156	NCIH1373	viability	ACTGGTTGCTCAAATGAAGCAGG	PHF21A	ENSG00000135365	-0.13031364181899477	[452]	[441,487,305,163]	-1	hSpCas9	negative selection	7987499
46084198	46084221	11	-	27260156	NCIH1373	viability	GATGGAGTTGCAGACTCTACAGG	PHF21A	ENSG00000135365	0.11164731915997217	[725]	[1574,838,619,151]	1	hSpCas9	negative selection	7987500
45979759	45979782	11	-	27260156	NCIH1373	viability	TCCCAACCTGACTGCTTCACAGG	PHF21A	ENSG00000135365	0.2153427334897462	[1713]	[3036,2136,1758,555]	2	hSpCas9	negative selection	8051750
46084174	46084197	11	-	27260156	NCIH1373	viability	GGCTCTTAAAGTGGAAATTCAGG	PHF21A	ENSG00000135365	-1.67382849472455	[199]	[104,99,41,8]	-9	hSpCas9	negative selection	8051751
45979943	45979966	11	-	27260156	NCIH1373	viability	AAAGAGTAGTTGAACAGCTACGG	PHF21A	ENSG00000135365	-0.03144929904555606	[474]	[701,289,520,164]	0	hSpCas9	negative selection	8051752
45979893	45979916	11	+	27260156	PATU8902	viability	GGCTGTATTTGGAACTTGTCCGG	PHF21A	ENSG00000135365	0.4281609777535378	[333]	[637,344,660,873]	4	hSpCas9	negative selection	8108749
46079142	46079165	11	-	27260156	PATU8902	viability	ACTGGTTGCTCAAATGAAGCAGG	PHF21A	ENSG00000135365	-0.08667059510471314	[452]	[679,375,514,849]	-1	hSpCas9	negative selection	8108750
46084198	46084221	11	-	27260156	PATU8902	viability	GATGGAGTTGCAGACTCTACAGG	PHF21A	ENSG00000135365	-0.2334295032550014	[725]	[921,1196,257,1260]	-2	hSpCas9	negative selection	8108751
45979759	45979782	11	-	27260156	PATU8902	viability	TCCCAACCTGACTGCTTCACAGG	PHF21A	ENSG00000135365	-0.13243311076141784	[1713]	[1909,3031,1804,2031]	-1	hSpCas9	negative selection	8173001
46084174	46084197	11	-	27260156	PATU8902	viability	GGCTCTTAAAGTGGAAATTCAGG	PHF21A	ENSG00000135365	-0.7651271089044969	[199]	[183,51,195,219]	-6	hSpCas9	negative selection	8173002
45979943	45979966	11	-	27260156	PATU8902	viability	AAAGAGTAGTTGAACAGCTACGG	PHF21A	ENSG00000135365	-0.38914973915238005	[474]	[661,333,207,938]	-4	hSpCas9	negative selection	8173003
45979893	45979916	11	+	27260156	PANC1	viability	GGCTGTATTTGGAACTTGTCCGG	PHF21A	ENSG00000135365	0.680163244351143	[333]	[471,568,455,370]	9	hSpCas9	negative selection	8230000
46079142	46079165	11	-	27260156	PANC1	viability	ACTGGTTGCTCAAATGAAGCAGG	PHF21A	ENSG00000135365	0.31757334914885	[452]	[480,691,508,319]	5	hSpCas9	negative selection	8230001
46084198	46084221	11	-	27260156	PANC1	viability	GATGGAGTTGCAGACTCTACAGG	PHF21A	ENSG00000135365	0.39263618698466773	[725]	[637,1086,792,803]	6	hSpCas9	negative selection	8230002
45979759	45979782	11	-	27260156	PANC1	viability	TCCCAACCTGACTGCTTCACAGG	PHF21A	ENSG00000135365	0.18808536859421143	[1713]	[1679,2299,1682,1221]	3	hSpCas9	negative selection	8294252
46084174	46084197	11	-	27260156	PANC1	viability	GGCTCTTAAAGTGGAAATTCAGG	PHF21A	ENSG00000135365	-1.071188848531853	[199]	[94,130,46,64]	-8	hSpCas9	negative selection	8294253
45979943	45979966	11	-	27260156	PANC1	viability	AAAGAGTAGTTGAACAGCTACGG	PHF21A	ENSG00000135365	0.14207370345795986	[474]	[417,504,543,354]	2	hSpCas9	negative selection	8294254
45979893	45979916	11	+	27260156	PANC0813	viability	GGCTGTATTTGGAACTTGTCCGG	PHF21A	ENSG00000135365	0.5850360831293744	[333]	[624,619,519,590]	8	hSpCas9	negative selection	8351251
46079142	46079165	11	-	27260156	PANC0813	viability	ACTGGTTGCTCAAATGAAGCAGG	PHF21A	ENSG00000135365	-0.11480978956470547	[452]	[484,530,438,507]	-2	hSpCas9	negative selection	8351252
46084198	46084221	11	-	27260156	PANC0813	viability	GATGGAGTTGCAGACTCTACAGG	PHF21A	ENSG00000135365	0.22113623365882984	[725]	[1092,789,1134,967]	3	hSpCas9	negative selection	8351253
45979759	45979782	11	-	27260156	PANC0813	viability	TCCCAACCTGACTGCTTCACAGG	PHF21A	ENSG00000135365	0.20321504539076618	[1713]	[2155,2859,2355,1903]	3	hSpCas9	negative selection	8415503
46084174	46084197	11	-	27260156	PANC0813	viability	GGCTCTTAAAGTGGAAATTCAGG	PHF21A	ENSG00000135365	-0.6930097008418556	[199]	[188,47,75,264]	-7	hSpCas9	negative selection	8415504
45979943	45979966	11	-	27260156	PANC0813	viability	AAAGAGTAGTTGAACAGCTACGG	PHF21A	ENSG00000135365	0.0294439109231215	[474]	[670,503,469,636]	0	hSpCas9	negative selection	8415505
45979893	45979916	11	+	27260156	RDES	viability	GGCTGTATTTGGAACTTGTCCGG	PHF21A	ENSG00000135365	0.5209535735567382	[333]	[474,514,631,594]	8	hSpCas9	negative selection	8472502
46079142	46079165	11	-	27260156	RDES	viability	ACTGGTTGCTCAAATGAAGCAGG	PHF21A	ENSG00000135365	-0.21993638340666924	[452]	[375,300,608,539]	-4	hSpCas9	negative selection	8472503
46084198	46084221	11	-	27260156	RDES	viability	GATGGAGTTGCAGACTCTACAGG	PHF21A	ENSG00000135365	-0.2236931415134899	[725]	[611,613,756,919]	-4	hSpCas9	negative selection	8472504
45979759	45979782	11	-	27260156	RDES	viability	TCCCAACCTGACTGCTTCACAGG	PHF21A	ENSG00000135365	-0.12602948701605365	[1713]	[1393,1619,1803,2579]	-2	hSpCas9	negative selection	8536754
46084174	46084197	11	-	27260156	RDES	viability	GGCTCTTAAAGTGGAAATTCAGG	PHF21A	ENSG00000135365	-0.7667965068919462	[199]	[119,104,173,146]	-8	hSpCas9	negative selection	8536755
45979943	45979966	11	-	27260156	RDES	viability	AAAGAGTAGTTGAACAGCTACGG	PHF21A	ENSG00000135365	-0.7225174303722859	[474]	[275,288,365,412]	-8	hSpCas9	negative selection	8536756
45979893	45979916	11	+	27260156	PC3	viability	GGCTGTATTTGGAACTTGTCCGG	PHF21A	ENSG00000135365	0.36786717625384574	[333]	[260,485,608,462]	7	hSpCas9	negative selection	8593753
46079142	46079165	11	-	27260156	PC3	viability	ACTGGTTGCTCAAATGAAGCAGG	PHF21A	ENSG00000135365	0.2949901577802469	[452]	[300,689,772,592]	6	hSpCas9	negative selection	8593754
46084198	46084221	11	-	27260156	PC3	viability	GATGGAGTTGCAGACTCTACAGG	PHF21A	ENSG00000135365	0.17461967065900763	[725]	[474,732,1490,915]	4	hSpCas9	negative selection	8593755
45979759	45979782	11	-	27260156	PC3	viability	TCCCAACCTGACTGCTTCACAGG	PHF21A	ENSG00000135365	0.02679716091415263	[1713]	[1174,1974,2634,1567]	0	hSpCas9	negative selection	8658005
46084174	46084197	11	-	27260156	PC3	viability	GGCTCTTAAAGTGGAAATTCAGG	PHF21A	ENSG00000135365	-0.5237195110529873	[199]	[115,72,256,151]	-8	hSpCas9	negative selection	8658006
45979943	45979966	11	-	27260156	PC3	viability	AAAGAGTAGTTGAACAGCTACGG	PHF21A	ENSG00000135365	-0.502779584584885	[474]	[160,314,579,431]	-8	hSpCas9	negative selection	8658007
45979893	45979916	11	+	27260156	PATU8988T	viability	GGCTGTATTTGGAACTTGTCCGG	PHF21A	ENSG00000135365	0.3695183123267096	[333]	[405,605,313,355]	6	hSpCas9	negative selection	8715004
46079142	46079165	11	-	27260156	PATU8988T	viability	ACTGGTTGCTCAAATGAAGCAGG	PHF21A	ENSG00000135365	0.2187299465208174	[452]	[828,288,317,589]	4	hSpCas9	negative selection	8715005
46084198	46084221	11	-	27260156	PATU8988T	viability	GATGGAGTTGCAGACTCTACAGG	PHF21A	ENSG00000135365	0.13931554650802536	[725]	[741,747,838,756]	2	hSpCas9	negative selection	8715006
45979759	45979782	11	-	27260156	PATU8988T	viability	TCCCAACCTGACTGCTTCACAGG	PHF21A	ENSG00000135365	-0.05756378852687272	[1713]	[1624,1530,1568,1638]	-1	hSpCas9	negative selection	8779256
46084174	46084197	11	-	27260156	PATU8988T	viability	GGCTCTTAAAGTGGAAATTCAGG	PHF21A	ENSG00000135365	-0.9788445516428363	[199]	[21,163,56,160]	-8	hSpCas9	negative selection	8779257
45979943	45979966	11	-	27260156	PATU8988T	viability	AAAGAGTAGTTGAACAGCTACGG	PHF21A	ENSG00000135365	-0.3789591265125812	[474]	[404,529,272,209]	-6	hSpCas9	negative selection	8779258
45979893	45979916	11	+	27260156	T47D	viability	GGCTGTATTTGGAACTTGTCCGG	PHF21A	ENSG00000135365	0.37407705867717744	[333]	[526,449,503,541]	7	hSpCas9	negative selection	8836255
46079142	46079165	11	-	27260156	T47D	viability	ACTGGTTGCTCAAATGAAGCAGG	PHF21A	ENSG00000135365	-0.011923728688788236	[452]	[534,531,563,458]	0	hSpCas9	negative selection	8836256
46084198	46084221	11	-	27260156	T47D	viability	GATGGAGTTGCAGACTCTACAGG	PHF21A	ENSG00000135365	0.08275064653670472	[725]	[847,910,976,841]	1	hSpCas9	negative selection	8836257
45979759	45979782	11	-	27260156	T47D	viability	TCCCAACCTGACTGCTTCACAGG	PHF21A	ENSG00000135365	-0.08635610575536212	[1713]	[2167,1666,1707,2005]	-2	hSpCas9	negative selection	8900507
46084174	46084197	11	-	27260156	T47D	viability	GGCTCTTAAAGTGGAAATTCAGG	PHF21A	ENSG00000135365	-0.7192601617146461	[199]	[142,78,175,173]	-8	hSpCas9	negative selection	8900508
45979943	45979966	11	-	27260156	T47D	viability	AAAGAGTAGTTGAACAGCTACGG	PHF21A	ENSG00000135365	-0.2787923173803619	[474]	[480,358,447,547]	-6	hSpCas9	negative selection	8900509
45979893	45979916	11	+	27260156	SU8686	viability	GGCTGTATTTGGAACTTGTCCGG	PHF21A	ENSG00000135365	0.5493821481833387	[333]	[407,361,579,636]	8	hSpCas9	negative selection	8957506
46079142	46079165	11	-	27260156	SU8686	viability	ACTGGTTGCTCAAATGAAGCAGG	PHF21A	ENSG00000135365	-0.06683407941130928	[452]	[442,373,389,524]	-1	hSpCas9	negative selection	8957507
46084198	46084221	11	-	27260156	SU8686	viability	GATGGAGTTGCAGACTCTACAGG	PHF21A	ENSG00000135365	0.16303009909261668	[725]	[761,645,841,1030]	2	hSpCas9	negative selection	8957508
45979759	45979782	11	-	27260156	SU8686	viability	TCCCAACCTGACTGCTTCACAGG	PHF21A	ENSG00000135365	-0.06920111732325407	[1713]	[1506,1538,1618,1864]	-1	hSpCas9	negative selection	9021758
46084174	46084197	11	-	27260156	SU8686	viability	GGCTCTTAAAGTGGAAATTCAGG	PHF21A	ENSG00000135365	-0.7126475818976694	[199]	[82,83,135,202]	-8	hSpCas9	negative selection	9021759
45979943	45979966	11	-	27260156	SU8686	viability	AAAGAGTAGTTGAACAGCTACGG	PHF21A	ENSG00000135365	-0.01051213455664085	[474]	[321,348,569,697]	0	hSpCas9	negative selection	9021760
45979893	45979916	11	+	27260156	SKES1	viability	GGCTGTATTTGGAACTTGTCCGG	PHF21A	ENSG00000135365	0.7496802878388316	[333]	[708,680,486,411]	9	hSpCas9	negative selection	9078757
46079142	46079165	11	-	27260156	SKES1	viability	ACTGGTTGCTCAAATGAAGCAGG	PHF21A	ENSG00000135365	-0.06767150097226327	[452]	[661,464,405,245]	-1	hSpCas9	negative selection	9078758
46084198	46084221	11	-	27260156	SKES1	viability	GATGGAGTTGCAGACTCTACAGG	PHF21A	ENSG00000135365	0.36171374577169735	[725]	[1141,1105,750,783]	7	hSpCas9	negative selection	9078759
45979759	45979782	11	-	27260156	SKES1	viability	TCCCAACCTGACTGCTTCACAGG	PHF21A	ENSG00000135365	-0.09428515555241557	[1713]	[1606,1699,1563,1538]	-2	hSpCas9	negative selection	9143009
46084174	46084197	11	-	27260156	SKES1	viability	GGCTCTTAAAGTGGAAATTCAGG	PHF21A	ENSG00000135365	-1.0368051026811163	[199]	[138,93,96,66]	-9	hSpCas9	negative selection	9143010
45979943	45979966	11	-	27260156	SKES1	viability	AAAGAGTAGTTGAACAGCTACGG	PHF21A	ENSG00000135365	-0.10356593277301515	[474]	[527,412,430,400]	-2	hSpCas9	negative selection	9143011
45979893	45979916	11	+	27260156	TOV112D	viability	GGCTGTATTTGGAACTTGTCCGG	PHF21A	ENSG00000135365	0.5380331122965271	[333]	[437,541,489,481]	8	hSpCas9	negative selection	9200008
46079142	46079165	11	-	27260156	TOV112D	viability	ACTGGTTGCTCAAATGAAGCAGG	PHF21A	ENSG00000135365	0.14406762197017361	[452]	[469,514,544,475]	3	hSpCas9	negative selection	9200009
46084198	46084221	11	-	27260156	TOV112D	viability	GATGGAGTTGCAGACTCTACAGG	PHF21A	ENSG00000135365	0.38544025574715857	[725]	[1112,872,982,826]	7	hSpCas9	negative selection	9200010
45979759	45979782	11	-	27260156	TOV112D	viability	TCCCAACCTGACTGCTTCACAGG	PHF21A	ENSG00000135365	-0.004291003175745711	[1713]	[1831,2215,1410,1523]	0	hSpCas9	negative selection	9264260
46084174	46084197	11	-	27260156	TOV112D	viability	GGCTCTTAAAGTGGAAATTCAGG	PHF21A	ENSG00000135365	-0.8929706179223573	[199]	[119,138,73,106]	-9	hSpCas9	negative selection	9264261
45979943	45979966	11	-	27260156	TOV112D	viability	AAAGAGTAGTTGAACAGCTACGG	PHF21A	ENSG00000135365	-0.7569071538049129	[474]	[312,310,246,264]	-9	hSpCas9	negative selection	9264262
45979893	45979916	11	+	27260156	TC71	viability	GGCTGTATTTGGAACTTGTCCGG	PHF21A	ENSG00000135365	0.2987140564688141	[333]	[421,488,469,375]	7	hSpCas9	negative selection	9321259
46079142	46079165	11	-	27260156	TC71	viability	ACTGGTTGCTCAAATGAAGCAGG	PHF21A	ENSG00000135365	0.057154289283407406	[452]	[393,533,632,454]	1	hSpCas9	negative selection	9321260
46084198	46084221	11	-	27260156	TC71	viability	GATGGAGTTGCAGACTCTACAGG	PHF21A	ENSG00000135365	0.45133155070115505	[725]	[883,1181,1168,1018]	9	hSpCas9	negative selection	9321261
45979759	45979782	11	-	27260156	TC71	viability	TCCCAACCTGACTGCTTCACAGG	PHF21A	ENSG00000135365	0.08993495906442517	[1713]	[2115,1791,1906,2007]	2	hSpCas9	negative selection	9385511
46084174	46084197	11	-	27260156	TC71	viability	GGCTCTTAAAGTGGAAATTCAGG	PHF21A	ENSG00000135365	-0.9052049883254898	[199]	[92,103,178,77]	-9	hSpCas9	negative selection	9385512
45979943	45979966	11	-	27260156	TC71	viability	AAAGAGTAGTTGAACAGCTACGG	PHF21A	ENSG00000135365	-0.08501476572888172	[474]	[517,454,383,570]	-2	hSpCas9	negative selection	9385513
45979893	45979916	11	+	27260156	TC32	viability	GGCTGTATTTGGAACTTGTCCGG	PHF21A	ENSG00000135365	0.3555472166073525	[333]	[350,239,615,486]	6	hSpCas9	negative selection	9442510
46079142	46079165	11	-	27260156	TC32	viability	ACTGGTTGCTCAAATGAAGCAGG	PHF21A	ENSG00000135365	-0.21703731528347933	[452]	[413,158,573,408]	-4	hSpCas9	negative selection	9442511
46084198	46084221	11	-	27260156	TC32	viability	GATGGAGTTGCAGACTCTACAGG	PHF21A	ENSG00000135365	0.026677045743239036	[725]	[596,461,961,876]	0	hSpCas9	negative selection	9442512
45979759	45979782	11	-	27260156	TC32	viability	TCCCAACCTGACTGCTTCACAGG	PHF21A	ENSG00000135365	-0.0016692210864144297	[1713]	[1472,1293,2049,1740]	0	hSpCas9	negative selection	9506762
46084174	46084197	11	-	27260156	TC32	viability	GGCTCTTAAAGTGGAAATTCAGG	PHF21A	ENSG00000135365	-0.1755634723497963	[199]	[205,141,106,194]	-3	hSpCas9	negative selection	9506763
45979943	45979966	11	-	27260156	TC32	viability	AAAGAGTAGTTGAACAGCTACGG	PHF21A	ENSG00000135365	-0.22157548091145532	[474]	[281,325,527,434]	-4	hSpCas9	negative selection	9506764
45965383	45965406	11	+	27869803	HPAFII	viability after 27 days	CTATCACAATGCTGGTGAGCTGG	PHF21A	ENSG00000135365	0.7445247788113614	[295]	[191,317,NaN]	6	hSpCas9	negative selection	9541587
45969816	45969839	11	+	27869803	HPAFII	viability after 27 days	TGTGGAAGAAAGTTTGGACGTGG	PHF21A	ENSG00000135365	0.46339530576777166	[493]	[476,258,NaN]	4	hSpCas9	negative selection	9541588
45971242	45971265	11	+	27869803	HPAFII	viability after 27 days	GATGGCGGTCACCATAGCAATGG	PHF21A	ENSG00000135365	0.5385381636298041	[189]	[209,90,NaN]	4	hSpCas9	negative selection	9541589
46049431	46049454	11	+	27869803	HPAFII	viability after 27 days	CACAGTGTATTCCTGTACAGTGG	PHF21A	ENSG00000135365	-0.4186975019274076	[477]	[319,77,NaN]	-3	hSpCas9	negative selection	9541590
46079142	46079165	11	-	27869803	HPAFII	viability after 27 days	ACTGGTTGCTCAAATGAAGCAGG	PHF21A	ENSG00000135365	-0.8462847226020318	[179]	[86,23,NaN]	-5	hSpCas9	negative selection	9541591
46084195	46084218	11	-	27869803	HPAFII	viability after 27 days	GGAGTTGCAGACTCTACAGGAGG	PHF21A	ENSG00000135365	-0.6851741983667762	[242]	[97,63,NaN]	-5	hSpCas9	negative selection	9541592
45965383	45965406	11	+	27869803	HPAFII	viability after 15 days	CTATCACAATGCTGGTGAGCTGG	PHF21A	ENSG00000135365	0.2800129663687394	[295]	[524,299,NaN]	3	hSpCas9	negative selection	9624036
45969816	45969839	11	+	27869803	HPAFII	viability after 15 days	TGTGGAAGAAAGTTTGGACGTGG	PHF21A	ENSG00000135365	0.20402556087057977	[493]	[1139,282,NaN]	2	hSpCas9	negative selection	9624037
45971242	45971265	11	+	27869803	HPAFII	viability after 15 days	GATGGCGGTCACCATAGCAATGG	PHF21A	ENSG00000135365	0.05297196573602686	[189]	[410,87,NaN]	0	hSpCas9	negative selection	9624038
46049431	46049454	11	+	27869803	HPAFII	viability after 15 days	CACAGTGTATTCCTGTACAGTGG	PHF21A	ENSG00000135365	-0.36694896691393264	[477]	[570,290,NaN]	-4	hSpCas9	negative selection	9624039
46079142	46079165	11	-	27869803	HPAFII	viability after 15 days	ACTGGTTGCTCAAATGAAGCAGG	PHF21A	ENSG00000135365	-0.03609561112729437	[179]	[237,157,NaN]	0	hSpCas9	negative selection	9624040
46084195	46084218	11	-	27869803	HPAFII	viability after 15 days	GGAGTTGCAGACTCTACAGGAGG	PHF21A	ENSG00000135365	-0.44003242872194354	[242]	[247,157,NaN]	-5	hSpCas9	negative selection	9624041
45965383	45965406	11	+	27869803	ASPC1	viability after 36 days	CTATCACAATGCTGGTGAGCTGG	PHF21A	ENSG00000135365	-0.17280616616573533	[600]	[293,95,179]	-2	hSpCas9	negative selection	9706485
45969816	45969839	11	+	27869803	ASPC1	viability after 36 days	TGTGGAAGAAAGTTTGGACGTGG	PHF21A	ENSG00000135365	-0.32585366501719437	[1196]	[474,367,202]	-3	hSpCas9	negative selection	9706486
45971242	45971265	11	+	27869803	ASPC1	viability after 36 days	GATGGCGGTCACCATAGCAATGG	PHF21A	ENSG00000135365	-0.6668861702100721	[312]	[66,96,46]	-6	hSpCas9	negative selection	9706487
46049431	46049454	11	+	27869803	ASPC1	viability after 36 days	CACAGTGTATTCCTGTACAGTGG	PHF21A	ENSG00000135365	0.13739753282461575	[1400]	[474,938,257]	1	hSpCas9	negative selection	9706488
46079142	46079165	11	-	27869803	ASPC1	viability after 36 days	ACTGGTTGCTCAAATGAAGCAGG	PHF21A	ENSG00000135365	0.31574647808645784	[317]	[183,221,37]	3	hSpCas9	negative selection	9706489
46084195	46084218	11	-	27869803	ASPC1	viability after 36 days	GGAGTTGCAGACTCTACAGGAGG	PHF21A	ENSG00000135365	-0.4769880847351673	[536]	[151,222,50]	-5	hSpCas9	negative selection	9706490
45965383	45965406	11	+	27869803	PATU8988S	viability after 35 days	CTATCACAATGCTGGTGAGCTGG	PHF21A	ENSG00000135365	1.0039161893479862	[546]	[575,306,NaN]	8	hSpCas9	negative selection	9788934
45969816	45969839	11	+	27869803	PATU8988S	viability after 35 days	TGTGGAAGAAAGTTTGGACGTGG	PHF21A	ENSG00000135365	0.7255166669894161	[980]	[780,524,NaN]	7	hSpCas9	negative selection	9788935
45971242	45971265	11	+	27869803	PATU8988S	viability after 35 days	GATGGCGGTCACCATAGCAATGG	PHF21A	ENSG00000135365	1.4165157570432383	[295]	[199,436,NaN]	9	hSpCas9	negative selection	9788936
46049431	46049454	11	+	27869803	PATU8988S	viability after 35 days	CACAGTGTATTCCTGTACAGTGG	PHF21A	ENSG00000135365	0.4141205148028051	[1108]	[662,526,NaN]	5	hSpCas9	negative selection	9788937
46079142	46079165	11	-	27869803	PATU8988S	viability after 35 days	ACTGGTTGCTCAAATGAAGCAGG	PHF21A	ENSG00000135365	0.1531290768744739	[400]	[217,140,NaN]	1	hSpCas9	negative selection	9788938
46084195	46084218	11	-	27869803	PATU8988S	viability after 35 days	GGAGTTGCAGACTCTACAGGAGG	PHF21A	ENSG00000135365	0.7264747733330237	[398]	[216,314,NaN]	7	hSpCas9	negative selection	9788939
45965383	45965406	11	+	27869803	PATU8988S	viability after 31 days	CTATCACAATGCTGGTGAGCTGG	PHF21A	ENSG00000135365	0.7369762170942454	[546]	[381,339,NaN]	8	hSpCas9	negative selection	9871383
45969816	45969839	11	+	27869803	PATU8988S	viability after 31 days	TGTGGAAGAAAGTTTGGACGTGG	PHF21A	ENSG00000135365	0.6113307003277951	[980]	[663,512,NaN]	7	hSpCas9	negative selection	9871384
45971242	45971265	11	+	27869803	PATU8988S	viability after 31 days	GATGGCGGTCACCATAGCAATGG	PHF21A	ENSG00000135365	1.1251946882190171	[295]	[139,406,NaN]	9	hSpCas9	negative selection	9871385
46049431	46049454	11	+	27869803	PATU8988S	viability after 31 days	CACAGTGTATTCCTGTACAGTGG	PHF21A	ENSG00000135365	0.40311786983706677	[1108]	[571,600,NaN]	5	hSpCas9	negative selection	9871386
46079142	46079165	11	-	27869803	PATU8988S	viability after 31 days	ACTGGTTGCTCAAATGAAGCAGG	PHF21A	ENSG00000135365	0.5207816839301452	[400]	[268,178,NaN]	6	hSpCas9	negative selection	9871387
46084195	46084218	11	-	27869803	PATU8988S	viability after 31 days	GGAGTTGCAGACTCTACAGGAGG	PHF21A	ENSG00000135365	0.4591408580849789	[398]	[201,239,NaN]	5	hSpCas9	negative selection	9871388
45965383	45965406	11	+	27869803	HPAFII	viability after 35 days	CTATCACAATGCTGGTGAGCTGG	PHF21A	ENSG00000135365	1.0268328971600669	[295]	[127,504,NaN]	7	hSpCas9	negative selection	9953832
45969816	45969839	11	+	27869803	HPAFII	viability after 35 days	TGTGGAAGAAAGTTTGGACGTGG	PHF21A	ENSG00000135365	0.2915563380844831	[493]	[378,223,NaN]	1	hSpCas9	negative selection	9953833
45971242	45971265	11	+	27869803	HPAFII	viability after 35 days	GATGGCGGTCACCATAGCAATGG	PHF21A	ENSG00000135365	0.6802778971849515	[189]	[68,249,NaN]	4	hSpCas9	negative selection	9953834
46049431	46049454	11	+	27869803	HPAFII	viability after 35 days	CACAGTGTATTCCTGTACAGTGG	PHF21A	ENSG00000135365	-0.5046320234427799	[477]	[234,97,NaN]	-3	hSpCas9	negative selection	9953835
46079142	46079165	11	-	27869803	HPAFII	viability after 35 days	ACTGGTTGCTCAAATGAAGCAGG	PHF21A	ENSG00000135365	0.03691644373733216	[179]	[124,57,NaN]	0	hSpCas9	negative selection	9953836
46084195	46084218	11	-	27869803	HPAFII	viability after 35 days	GGAGTTGCAGACTCTACAGGAGG	PHF21A	ENSG00000135365	-0.07518881100659883	[242]	[128,102,NaN]	0	hSpCas9	negative selection	9953837
45965383	45965406	11	+	27869803	HPAFII	viability after 31 days	CTATCACAATGCTGGTGAGCTGG	PHF21A	ENSG00000135365	0.8501235686992835	[295]	[130,482,NaN]	6	hSpCas9	negative selection	10036281
45969816	45969839	11	+	27869803	HPAFII	viability after 31 days	TGTGGAAGAAAGTTTGGACGTGG	PHF21A	ENSG00000135365	0.582741057476316	[493]	[542,275,NaN]	4	hSpCas9	negative selection	10036282
45971242	45971265	11	+	27869803	HPAFII	viability after 31 days	GATGGCGGTCACCATAGCAATGG	PHF21A	ENSG00000135365	0.2665716386186004	[189]	[178,72,NaN]	2	hSpCas9	negative selection	10036283
46049431	46049454	11	+	27869803	HPAFII	viability after 31 days	CACAGTGTATTCCTGTACAGTGG	PHF21A	ENSG00000135365	-0.522586357104774	[477]	[247,119,NaN]	-3	hSpCas9	negative selection	10036284
46079142	46079165	11	-	27869803	HPAFII	viability after 31 days	ACTGGTTGCTCAAATGAAGCAGG	PHF21A	ENSG00000135365	-0.4828432440177109	[179]	[100,40,NaN]	-3	hSpCas9	negative selection	10036285
46084195	46084218	11	-	27869803	HPAFII	viability after 31 days	GGAGTTGCAGACTCTACAGGAGG	PHF21A	ENSG00000135365	-0.584326271991653	[242]	[89,91,NaN]	-4	hSpCas9	negative selection	10036286
46084195	46084218	11	-	28162770	P31FUJ	viability	GGAGTTGCAGACTCTACAGGAGG	PHF21A	ENSG00000135365	-0.07473735818212723	[284]	[317]	0	hSpCas9	negative selection	10210516
45948900	45948923	11	-	28162770	P31FUJ	viability	CTAAACAGCACAATGCACCCTGG	PHF21A	ENSG00000135365	0.06724277257453404	[371]	[457]	0	hSpCas9	negative selection	10210517
45971266	45971289	11	+	28162770	P31FUJ	viability	AGGTCTCTGGCCCACCACAGAGG	PHF21A	ENSG00000135365	-0.22274853975045583	[142]	[143]	-2	hSpCas9	negative selection	10210518
45971242	45971265	11	+	28162770	P31FUJ	viability	GATGGCGGTCACCATAGCAATGG	PHF21A	ENSG00000135365	0.4021121182821302	[122]	[190]	4	hSpCas9	negative selection	10210519
45965538	45965561	11	+	28162770	P31FUJ	viability	GGAGCTGCGAGCATGGGAGGTGG	PHF21A	ENSG00000135365	-1.3950736333132556	[93]	[41]	-7	hSpCas9	negative selection	10210520
45965443	45965466	11	+	28162770	P31FUJ	viability	CATTGACGACACGGACGGGGTGG	PHF21A	ENSG00000135365	0.43962313755711735	[31]	[50]	5	hSpCas9	negative selection	10210521
45979780	45979803	11	+	28162770	P31FUJ	viability	GAGAGGCTGCAGCTGACTGCTGG	PHF21A	ENSG00000135365	0.28581780147808156	[177]	[254]	3	hSpCas9	negative selection	10210522
45965522	45965545	11	-	28162770	P31FUJ	viability	CAGCTCCTCAGCTTATCCAGAGG	PHF21A	ENSG00000135365	-0.6412670497697361	[145]	[109]	-5	hSpCas9	negative selection	10210523
45965390	45965413	11	+	28162770	P31FUJ	viability	AATGCTGGTGAGCTGGGCCATGG	PHF21A	ENSG00000135365	0.15811250066429128	[195]	[256]	1	hSpCas9	negative selection	10210524
45953538	45953561	11	-	28162770	P31FUJ	viability	TGCACCCAAACCAAAACGGGAGG	PHF21A	ENSG00000135365	0.09120021871084227	[138]	[173]	0	hSpCas9	negative selection	10210525
46084195	46084218	11	-	28162770	TF1	viability	GGAGTTGCAGACTCTACAGGAGG	PHF21A	ENSG00000135365	NaN	[NaN]	[279]	1	hSpCas9	negative selection	10379882
45948900	45948923	11	-	28162770	TF1	viability	CTAAACAGCACAATGCACCCTGG	PHF21A	ENSG00000135365	NaN	[NaN]	[355]	1	hSpCas9	negative selection	10379883
45971266	45971289	11	+	28162770	TF1	viability	AGGTCTCTGGCCCACCACAGAGG	PHF21A	ENSG00000135365	NaN	[NaN]	[163]	1	hSpCas9	negative selection	10379884
45971242	45971265	11	+	28162770	TF1	viability	GATGGCGGTCACCATAGCAATGG	PHF21A	ENSG00000135365	NaN	[NaN]	[124]	1	hSpCas9	negative selection	10379885
45965538	45965561	11	+	28162770	TF1	viability	GGAGCTGCGAGCATGGGAGGTGG	PHF21A	ENSG00000135365	NaN	[NaN]	[40]	1	hSpCas9	negative selection	10379886
45965443	45965466	11	+	28162770	TF1	viability	CATTGACGACACGGACGGGGTGG	PHF21A	ENSG00000135365	NaN	[NaN]	[75]	1	hSpCas9	negative selection	10379887
45979780	45979803	11	+	28162770	TF1	viability	GAGAGGCTGCAGCTGACTGCTGG	PHF21A	ENSG00000135365	NaN	[NaN]	[325]	1	hSpCas9	negative selection	10379888
45965522	45965545	11	-	28162770	TF1	viability	CAGCTCCTCAGCTTATCCAGAGG	PHF21A	ENSG00000135365	NaN	[NaN]	[80]	1	hSpCas9	negative selection	10379889
45965390	45965413	11	+	28162770	TF1	viability	AATGCTGGTGAGCTGGGCCATGG	PHF21A	ENSG00000135365	NaN	[NaN]	[225]	1	hSpCas9	negative selection	10379890
45953538	45953561	11	-	28162770	TF1	viability	TGCACCCAAACCAAAACGGGAGG	PHF21A	ENSG00000135365	NaN	[NaN]	[156]	1	hSpCas9	negative selection	10379891
46084195	46084218	11	-	28162770	SKM1	viability	GGAGTTGCAGACTCTACAGGAGG	PHF21A	ENSG00000135365	-0.7336458236011587	[94]	[100]	-5	hSpCas9	negative selection	10549248
45948900	45948923	11	-	28162770	SKM1	viability	CTAAACAGCACAATGCACCCTGG	PHF21A	ENSG00000135365	-0.4675709634473139	[78]	[100]	-4	hSpCas9	negative selection	10549249
45971266	45971289	11	+	28162770	SKM1	viability	AGGTCTCTGGCCCACCACAGAGG	PHF21A	ENSG00000135365	-0.84799690655495	[55]	[54]	-6	hSpCas9	negative selection	10549250
45971242	45971265	11	+	28162770	SKM1	viability	GATGGCGGTCACCATAGCAATGG	PHF21A	ENSG00000135365	-0.8220016980220057	[28]	[28]	-6	hSpCas9	negative selection	10549251
45965538	45965561	11	+	28162770	SKM1	viability	GGAGCTGCGAGCATGGGAGGTGG	PHF21A	ENSG00000135365	-1.036126503374853	[28]	[24]	-6	hSpCas9	negative selection	10549252
45965443	45965466	11	+	28162770	SKM1	viability	CATTGACGACACGGACGGGGTGG	PHF21A	ENSG00000135365	-0.11573290107871581	[18]	[30]	-1	hSpCas9	negative selection	10549253
45979780	45979803	11	+	28162770	SKM1	viability	GAGAGGCTGCAGCTGACTGCTGG	PHF21A	ENSG00000135365	-0.25810081282867897	[45]	[67]	-2	hSpCas9	negative selection	10549254
45965522	45965545	11	-	28162770	SKM1	viability	CAGCTCCTCAGCTTATCCAGAGG	PHF21A	ENSG00000135365	1.67624916950582	[19]	[112]	9	hSpCas9	negative selection	10549255
45965390	45965413	11	+	28162770	SKM1	viability	AATGCTGGTGAGCTGGGCCATGG	PHF21A	ENSG00000135365	1.4937741698837617	[46]	[233]	9	hSpCas9	negative selection	10549256
45953538	45953561	11	-	28162770	SKM1	viability	TGCACCCAAACCAAAACGGGAGG	PHF21A	ENSG00000135365	0.48285288350641553	[33]	[83]	5	hSpCas9	negative selection	10549257
46084195	46084218	11	-	28162770	SKM1	viability	GGAGTTGCAGACTCTACAGGAGG	PHF21A	ENSG00000135365	-0.7336458236011587	[94]	[100]	-5	hSpCas9	negative selection	10718614
45948900	45948923	11	-	28162770	SKM1	viability	CTAAACAGCACAATGCACCCTGG	PHF21A	ENSG00000135365	-0.4675709634473139	[78]	[100]	-4	hSpCas9	negative selection	10718615
45971266	45971289	11	+	28162770	SKM1	viability	AGGTCTCTGGCCCACCACAGAGG	PHF21A	ENSG00000135365	-0.84799690655495	[55]	[54]	-6	hSpCas9	negative selection	10718616
45971242	45971265	11	+	28162770	SKM1	viability	GATGGCGGTCACCATAGCAATGG	PHF21A	ENSG00000135365	-0.8220016980220057	[28]	[28]	-6	hSpCas9	negative selection	10718617
45965538	45965561	11	+	28162770	SKM1	viability	GGAGCTGCGAGCATGGGAGGTGG	PHF21A	ENSG00000135365	-1.036126503374853	[28]	[24]	-6	hSpCas9	negative selection	10718618
45965443	45965466	11	+	28162770	SKM1	viability	CATTGACGACACGGACGGGGTGG	PHF21A	ENSG00000135365	-0.11573290107871581	[18]	[30]	-1	hSpCas9	negative selection	10718619
45979780	45979803	11	+	28162770	SKM1	viability	GAGAGGCTGCAGCTGACTGCTGG	PHF21A	ENSG00000135365	-0.25810081282867897	[45]	[67]	-2	hSpCas9	negative selection	10718620
45965522	45965545	11	-	28162770	SKM1	viability	CAGCTCCTCAGCTTATCCAGAGG	PHF21A	ENSG00000135365	1.67624916950582	[19]	[112]	9	hSpCas9	negative selection	10718621
45965390	45965413	11	+	28162770	SKM1	viability	AATGCTGGTGAGCTGGGCCATGG	PHF21A	ENSG00000135365	1.4937741698837617	[46]	[233]	9	hSpCas9	negative selection	10718622
45953538	45953561	11	-	28162770	SKM1	viability	TGCACCCAAACCAAAACGGGAGG	PHF21A	ENSG00000135365	0.48285288350641553	[33]	[83]	5	hSpCas9	negative selection	10718623
46084195	46084218	11	-	28162770	PL21	viability	GGAGTTGCAGACTCTACAGGAGG	PHF21A	ENSG00000135365	-0.24979609277411383	[264]	[96]	-2	hSpCas9	negative selection	10887980
45948900	45948923	11	-	28162770	PL21	viability	CTAAACAGCACAATGCACCCTGG	PHF21A	ENSG00000135365	-0.2901860120937609	[294]	[104]	-2	hSpCas9	negative selection	10887981
45971266	45971289	11	+	28162770	PL21	viability	AGGTCTCTGGCCCACCACAGAGG	PHF21A	ENSG00000135365	0.25136493784449326	[165]	[85]	2	hSpCas9	negative selection	10887982
45971242	45971265	11	+	28162770	PL21	viability	GATGGCGGTCACCATAGCAATGG	PHF21A	ENSG00000135365	-2.2946250772602577	[123]	[10]	-8	hSpCas9	negative selection	10887983
45965538	45965561	11	+	28162770	PL21	viability	GGAGCTGCGAGCATGGGAGGTGG	PHF21A	ENSG00000135365	-0.22070350647072923	[82]	[30]	-1	hSpCas9	negative selection	10887984
45965443	45965466	11	+	28162770	PL21	viability	CATTGACGACACGGACGGGGTGG	PHF21A	ENSG00000135365	0.9024590658486351	[58]	[47]	7	hSpCas9	negative selection	10887985
45979780	45979803	11	+	28162770	PL21	viability	GAGAGGCTGCAGCTGACTGCTGG	PHF21A	ENSG00000135365	-0.6902358943361818	[151]	[40]	-5	hSpCas9	negative selection	10887986
45965522	45965545	11	-	28162770	PL21	viability	CAGCTCCTCAGCTTATCCAGAGG	PHF21A	ENSG00000135365	0.7026399550185034	[95]	[67]	6	hSpCas9	negative selection	10887987
45965390	45965413	11	+	28162770	PL21	viability	AATGCTGGTGAGCTGGGCCATGG	PHF21A	ENSG00000135365	-0.1556220754739176	[150]	[58]	-1	hSpCas9	negative selection	10887988
45953538	45953561	11	-	28162770	PL21	viability	TGCACCCAAACCAAAACGGGAGG	PHF21A	ENSG00000135365	0.20013961448932005	[85]	[42]	1	hSpCas9	negative selection	10887989
46084195	46084218	11	-	28162770	P31FUJ	viability	GGAGTTGCAGACTCTACAGGAGG	PHF21A	ENSG00000135365	-0.07473735818212723	[284]	[317]	0	hSpCas9	negative selection	11057346
45948900	45948923	11	-	28162770	P31FUJ	viability	CTAAACAGCACAATGCACCCTGG	PHF21A	ENSG00000135365	0.06724277257453404	[371]	[457]	0	hSpCas9	negative selection	11057347
45971266	45971289	11	+	28162770	P31FUJ	viability	AGGTCTCTGGCCCACCACAGAGG	PHF21A	ENSG00000135365	-0.22274853975045583	[142]	[143]	-2	hSpCas9	negative selection	11057348
45971242	45971265	11	+	28162770	P31FUJ	viability	GATGGCGGTCACCATAGCAATGG	PHF21A	ENSG00000135365	0.4021121182821302	[122]	[190]	4	hSpCas9	negative selection	11057349
45965538	45965561	11	+	28162770	P31FUJ	viability	GGAGCTGCGAGCATGGGAGGTGG	PHF21A	ENSG00000135365	-1.3950736333132556	[93]	[41]	-7	hSpCas9	negative selection	11057350
45965443	45965466	11	+	28162770	P31FUJ	viability	CATTGACGACACGGACGGGGTGG	PHF21A	ENSG00000135365	0.43962313755711735	[31]	[50]	5	hSpCas9	negative selection	11057351
45979780	45979803	11	+	28162770	P31FUJ	viability	GAGAGGCTGCAGCTGACTGCTGG	PHF21A	ENSG00000135365	0.28581780147808156	[177]	[254]	3	hSpCas9	negative selection	11057352
45965522	45965545	11	-	28162770	P31FUJ	viability	CAGCTCCTCAGCTTATCCAGAGG	PHF21A	ENSG00000135365	-0.6412670497697361	[145]	[109]	-5	hSpCas9	negative selection	11057353
45965390	45965413	11	+	28162770	P31FUJ	viability	AATGCTGGTGAGCTGGGCCATGG	PHF21A	ENSG00000135365	0.15811250066429128	[195]	[256]	1	hSpCas9	negative selection	11057354
45953538	45953561	11	-	28162770	P31FUJ	viability	TGCACCCAAACCAAAACGGGAGG	PHF21A	ENSG00000135365	0.09120021871084227	[138]	[173]	0	hSpCas9	negative selection	11057355
46084195	46084218	11	-	28162770	OCIAML5	viability	GGAGTTGCAGACTCTACAGGAGG	PHF21A	ENSG00000135365	-2.7646037296136576	[127]	[33]	-8	hSpCas9	negative selection	11226712
45948900	45948923	11	-	28162770	OCIAML5	viability	CTAAACAGCACAATGCACCCTGG	PHF21A	ENSG00000135365	0.4879709045750973	[189]	[480]	4	hSpCas9	negative selection	11226713
45971266	45971289	11	+	28162770	OCIAML5	viability	AGGTCTCTGGCCCACCACAGAGG	PHF21A	ENSG00000135365	0.5687765500960524	[61]	[165]	5	hSpCas9	negative selection	11226714
45971242	45971265	11	+	28162770	OCIAML5	viability	GATGGCGGTCACCATAGCAATGG	PHF21A	ENSG00000135365	0.2750453470393426	[37]	[82]	2	hSpCas9	negative selection	11226715
45965538	45965561	11	+	28162770	OCIAML5	viability	GGAGCTGCGAGCATGGGAGGTGG	PHF21A	ENSG00000135365	-3.568273604863405	[45]	[6]	-9	hSpCas9	negative selection	11226716
45965443	45965466	11	+	28162770	OCIAML5	viability	CATTGACGACACGGACGGGGTGG	PHF21A	ENSG00000135365	-2.346831262613575	[30]	[10]	-8	hSpCas9	negative selection	11226717
45979780	45979803	11	+	28162770	OCIAML5	viability	GAGAGGCTGCAGCTGACTGCTGG	PHF21A	ENSG00000135365	0.21557214601136615	[124]	[261]	1	hSpCas9	negative selection	11226718
45965522	45965545	11	-	28162770	OCIAML5	viability	CAGCTCCTCAGCTTATCCAGAGG	PHF21A	ENSG00000135365	0.28381685721777605	[80]	[177]	2	hSpCas9	negative selection	11226719
45965390	45965413	11	+	28162770	OCIAML5	viability	AATGCTGGTGAGCTGGGCCATGG	PHF21A	ENSG00000135365	0.08264196888428382	[112]	[215]	0	hSpCas9	negative selection	11226720
45953538	45953561	11	-	28162770	OCIAML5	viability	TGCACCCAAACCAAAACGGGAGG	PHF21A	ENSG00000135365	0.5779212698808183	[71]	[193]	5	hSpCas9	negative selection	11226721
46084195	46084218	11	-	28162770	EOL1	viability	GGAGTTGCAGACTCTACAGGAGG	PHF21A	ENSG00000135365	-0.6097886560806536	[587]	[202]	-4	hSpCas9	negative selection	11396078
45948900	45948923	11	-	28162770	EOL1	viability	CTAAACAGCACAATGCACCCTGG	PHF21A	ENSG00000135365	-0.3407967949504602	[374]	[155]	-3	hSpCas9	negative selection	11396079
45971266	45971289	11	+	28162770	EOL1	viability	AGGTCTCTGGCCCACCACAGAGG	PHF21A	ENSG00000135365	0.3662532213114583	[267]	[181]	3	hSpCas9	negative selection	11396080
45971242	45971265	11	+	28162770	EOL1	viability	GATGGCGGTCACCATAGCAATGG	PHF21A	ENSG00000135365	0.28798407436216594	[184]	[118]	2	hSpCas9	negative selection	11396081
45965538	45965561	11	+	28162770	EOL1	viability	GGAGCTGCGAGCATGGGAGGTGG	PHF21A	ENSG00000135365	-2.7193084182041902	[124]	[9]	-9	hSpCas9	negative selection	11396082
45965443	45965466	11	+	28162770	EOL1	viability	CATTGACGACACGGACGGGGTGG	PHF21A	ENSG00000135365	-2.2805666583340782	[82]	[8]	-8	hSpCas9	negative selection	11396083
45979780	45979803	11	+	28162770	EOL1	viability	GAGAGGCTGCAGCTGACTGCTGG	PHF21A	ENSG00000135365	0.5159080434898411	[149]	[112]	4	hSpCas9	negative selection	11396084
45965522	45965545	11	-	28162770	EOL1	viability	CAGCTCCTCAGCTTATCCAGAGG	PHF21A	ENSG00000135365	1.6237400231048156	[177]	[288]	9	hSpCas9	negative selection	11396085
45965390	45965413	11	+	28162770	EOL1	viability	AATGCTGGTGAGCTGGGCCATGG	PHF21A	ENSG00000135365	0.33958527084937845	[239]	[159]	3	hSpCas9	negative selection	11396086
45953538	45953561	11	-	28162770	EOL1	viability	TGCACCCAAACCAAAACGGGAGG	PHF21A	ENSG00000135365	-0.16426149538732138	[133]	[62]	-1	hSpCas9	negative selection	11396087
46084195	46084218	11	-	28162770	MOLM13	viability	GGAGTTGCAGACTCTACAGGAGG	PHF21A	ENSG00000135365	0.19915824554126105	[405]	[336]	1	hSpCas9	negative selection	11565444
45948900	45948923	11	-	28162770	MOLM13	viability	CTAAACAGCACAATGCACCCTGG	PHF21A	ENSG00000135365	-0.3315995257602695	[502]	[288]	-2	hSpCas9	negative selection	11565445
45971266	45971289	11	+	28162770	MOLM13	viability	AGGTCTCTGGCCCACCACAGAGG	PHF21A	ENSG00000135365	0.08272241184787268	[238]	[182]	0	hSpCas9	negative selection	11565446
45971242	45971265	11	+	28162770	MOLM13	viability	GATGGCGGTCACCATAGCAATGG	PHF21A	ENSG00000135365	0.5622167640927318	[147]	[157]	4	hSpCas9	negative selection	11565447
45965538	45965561	11	+	28162770	MOLM13	viability	GGAGCTGCGAGCATGGGAGGTGG	PHF21A	ENSG00000135365	-0.2390636435551876	[110]	[67]	-1	hSpCas9	negative selection	11565448
45965443	45965466	11	+	28162770	MOLM13	viability	CATTGACGACACGGACGGGGTGG	PHF21A	ENSG00000135365	-0.7314194266788276	[61]	[26]	-4	hSpCas9	negative selection	11565449
45979780	45979803	11	+	28162770	MOLM13	viability	GAGAGGCTGCAGCTGACTGCTGG	PHF21A	ENSG00000135365	-0.6262327958199713	[189]	[88]	-4	hSpCas9	negative selection	11565450
45965522	45965545	11	-	28162770	MOLM13	viability	CAGCTCCTCAGCTTATCCAGAGG	PHF21A	ENSG00000135365	-0.8540387133427835	[164]	[65]	-5	hSpCas9	negative selection	11565451
45965390	45965413	11	+	28162770	MOLM13	viability	AATGCTGGTGAGCTGGGCCATGG	PHF21A	ENSG00000135365	-0.5753638164093053	[236]	[114]	-3	hSpCas9	negative selection	11565452
45953538	45953561	11	-	28162770	MOLM13	viability	TGCACCCAAACCAAAACGGGAGG	PHF21A	ENSG00000135365	-1.7951450242892153	[143]	[29]	-7	hSpCas9	negative selection	11565453
46084195	46084218	11	-	28162770	HEL	viability	GGAGTTGCAGACTCTACAGGAGG	PHF21A	ENSG00000135365	0.9185405339080287	[374]	[453]	7	hSpCas9	negative selection	11734810
45948900	45948923	11	-	28162770	HEL	viability	CTAAACAGCACAATGCACCCTGG	PHF21A	ENSG00000135365	0.2577585665776929	[379]	[290]	2	hSpCas9	negative selection	11734811
45971266	45971289	11	+	28162770	HEL	viability	AGGTCTCTGGCCCACCACAGAGG	PHF21A	ENSG00000135365	-1.06105989823065	[214]	[65]	-6	hSpCas9	negative selection	11734812
45971242	45971265	11	+	28162770	HEL	viability	GATGGCGGTCACCATAGCAATGG	PHF21A	ENSG00000135365	0.5447067490398303	[136]	[127]	4	hSpCas9	negative selection	11734813
45965538	45965561	11	+	28162770	HEL	viability	GGAGCTGCGAGCATGGGAGGTGG	PHF21A	ENSG00000135365	-1.6791892628870058	[114]	[22]	-7	hSpCas9	negative selection	11734814
45965443	45965466	11	+	28162770	HEL	viability	CATTGACGACACGGACGGGGTGG	PHF21A	ENSG00000135365	0.23611357253771326	[56]	[42]	2	hSpCas9	negative selection	11734815
45979780	45979803	11	+	28162770	HEL	viability	GAGAGGCTGCAGCTGACTGCTGG	PHF21A	ENSG00000135365	0.2869103304947039	[182]	[142]	2	hSpCas9	negative selection	11734816
45965522	45965545	11	-	28162770	HEL	viability	CAGCTCCTCAGCTTATCCAGAGG	PHF21A	ENSG00000135365	-0.9970856037553176	[133]	[42]	-6	hSpCas9	negative selection	11734817
45965390	45965413	11	+	28162770	HEL	viability	AATGCTGGTGAGCTGGGCCATGG	PHF21A	ENSG00000135365	0.8788061902338814	[179]	[211]	7	hSpCas9	negative selection	11734818
45953538	45953561	11	-	28162770	HEL	viability	TGCACCCAAACCAAAACGGGAGG	PHF21A	ENSG00000135365	-0.19376243571676366	[149]	[83]	-1	hSpCas9	negative selection	11734819
46084195	46084218	11	-	28162770	MV411	viability	GGAGTTGCAGACTCTACAGGAGG	PHF21A	ENSG00000135365	-0.3375249499383807	[263]	[175]	-3	hSpCas9	negative selection	11904176
45948900	45948923	11	-	28162770	MV411	viability	CTAAACAGCACAATGCACCCTGG	PHF21A	ENSG00000135365	0.5616653869885557	[262]	[326]	5	hSpCas9	negative selection	11904177
45971266	45971289	11	+	28162770	MV411	viability	AGGTCTCTGGCCCACCACAGAGG	PHF21A	ENSG00000135365	-0.3135194869275916	[148]	[100]	-2	hSpCas9	negative selection	11904178
45971242	45971265	11	+	28162770	MV411	viability	GATGGCGGTCACCATAGCAATGG	PHF21A	ENSG00000135365	-1.7525624492172245	[67]	[16]	-8	hSpCas9	negative selection	11904179
45965538	45965561	11	+	28162770	MV411	viability	GGAGCTGCGAGCATGGGAGGTGG	PHF21A	ENSG00000135365	0.11498725475912597	[56]	[51]	1	hSpCas9	negative selection	11904180
45965443	45965466	11	+	28162770	MV411	viability	CATTGACGACACGGACGGGGTGG	PHF21A	ENSG00000135365	-1.2000214261884459	[29]	[10]	-7	hSpCas9	negative selection	11904181
45979780	45979803	11	+	28162770	MV411	viability	GAGAGGCTGCAGCTGACTGCTGG	PHF21A	ENSG00000135365	0.5292085191981548	[152]	[185]	5	hSpCas9	negative selection	11904182
45965522	45965545	11	-	28162770	MV411	viability	CAGCTCCTCAGCTTATCCAGAGG	PHF21A	ENSG00000135365	-1.0888458370816572	[100]	[39]	-6	hSpCas9	negative selection	11904183
45965390	45965413	11	+	28162770	MV411	viability	AATGCTGGTGAGCTGGGCCATGG	PHF21A	ENSG00000135365	0.9609441721249925	[185]	[304]	8	hSpCas9	negative selection	11904184
45953538	45953561	11	-	28162770	MV411	viability	TGCACCCAAACCAAAACGGGAGG	PHF21A	ENSG00000135365	-0.8102779470735122	[101]	[48]	-5	hSpCas9	negative selection	11904185
46084195	46084218	11	-	28162770	MONOMAC1	viability	GGAGTTGCAGACTCTACAGGAGG	PHF21A	ENSG00000135365	-0.7266563139369349	[178]	[123]	-5	hSpCas9	negative selection	12073542
45948900	45948923	11	-	28162770	MONOMAC1	viability	CTAAACAGCACAATGCACCCTGG	PHF21A	ENSG00000135365	0.24128750475520588	[168]	[228]	2	hSpCas9	negative selection	12073543
45971266	45971289	11	+	28162770	MONOMAC1	viability	AGGTCTCTGGCCCACCACAGAGG	PHF21A	ENSG00000135365	0.9634278251336923	[84]	[189]	8	hSpCas9	negative selection	12073544
45971242	45971265	11	+	28162770	MONOMAC1	viability	GATGGCGGTCACCATAGCAATGG	PHF21A	ENSG00000135365	-0.6966078565500653	[81]	[57]	-5	hSpCas9	negative selection	12073545
45965538	45965561	11	+	28162770	MONOMAC1	viability	GGAGCTGCGAGCATGGGAGGTGG	PHF21A	ENSG00000135365	-0.7445246423620471	[56]	[38]	-6	hSpCas9	negative selection	12073546
45965443	45965466	11	+	28162770	MONOMAC1	viability	CATTGACGACACGGACGGGGTGG	PHF21A	ENSG00000135365	-2.3345403708094885	[21]	[4]	-9	hSpCas9	negative selection	12073547
45979780	45979803	11	+	28162770	MONOMAC1	viability	GAGAGGCTGCAGCTGACTGCTGG	PHF21A	ENSG00000135365	-0.029309401321487405	[72]	[81]	0	hSpCas9	negative selection	12073548
45965522	45965545	11	-	28162770	MONOMAC1	viability	CAGCTCCTCAGCTTATCCAGAGG	PHF21A	ENSG00000135365	0.1552648968713275	[46]	[59]	1	hSpCas9	negative selection	12073549
45965390	45965413	11	+	28162770	MONOMAC1	viability	AATGCTGGTGAGCTGGGCCATGG	PHF21A	ENSG00000135365	0.21800065221929008	[113]	[151]	2	hSpCas9	negative selection	12073550
45953538	45953561	11	-	28162770	MONOMAC1	viability	TGCACCCAAACCAAAACGGGAGG	PHF21A	ENSG00000135365	-0.39497622467146265	[77]	[67]	-3	hSpCas9	negative selection	12073551
46084195	46084218	11	-	28162770	OCIAML2	viability	GGAGTTGCAGACTCTACAGGAGG	PHF21A	ENSG00000135365	0.2546539638764097	[61]	[409]	2	hSpCas9	negative selection	12242908
45948900	45948923	11	-	28162770	OCIAML2	viability	CTAAACAGCACAATGCACCCTGG	PHF21A	ENSG00000135365	0.37658108562955606	[50]	[366]	3	hSpCas9	negative selection	12242909
45971266	45971289	11	+	28162770	OCIAML2	viability	AGGTCTCTGGCCCACCACAGAGG	PHF21A	ENSG00000135365	-0.7142989062090238	[36]	[124]	-5	hSpCas9	negative selection	12242910
45971242	45971265	11	+	28162770	OCIAML2	viability	GATGGCGGTCACCATAGCAATGG	PHF21A	ENSG00000135365	1.3172727341492705	[15]	[220]	9	hSpCas9	negative selection	12242911
45965538	45965561	11	+	28162770	OCIAML2	viability	GGAGCTGCGAGCATGGGAGGTGG	PHF21A	ENSG00000135365	-1.2482374039057134	[20]	[48]	-7	hSpCas9	negative selection	12242912
45965443	45965466	11	+	28162770	OCIAML2	viability	CATTGACGACACGGACGGGGTGG	PHF21A	ENSG00000135365	-0.583104554500574	[9]	[36]	-4	hSpCas9	negative selection	12242913
45979780	45979803	11	+	28162770	OCIAML2	viability	GAGAGGCTGCAGCTGACTGCTGG	PHF21A	ENSG00000135365	0.37306694387916334	[27]	[200]	3	hSpCas9	negative selection	12242914
45965522	45965545	11	-	28162770	OCIAML2	viability	CAGCTCCTCAGCTTATCCAGAGG	PHF21A	ENSG00000135365	0.17573322014313836	[22]	[143]	1	hSpCas9	negative selection	12242915
45965390	45965413	11	+	28162770	OCIAML2	viability	AATGCTGGTGAGCTGGGCCATGG	PHF21A	ENSG00000135365	-0.3222379853494901	[29]	[132]	-3	hSpCas9	negative selection	12242916
45953538	45953561	11	-	28162770	OCIAML2	viability	TGCACCCAAACCAAAACGGGAGG	PHF21A	ENSG00000135365	-0.14870173035479894	[19]	[99]	-1	hSpCas9	negative selection	12242917
46084195	46084218	11	-	28162770	OCIAML3	viability	GGAGTTGCAGACTCTACAGGAGG	PHF21A	ENSG00000135365	0.23488044328308233	[75]	[269]	2	hSpCas9	negative selection	12412274
45948900	45948923	11	-	28162770	OCIAML3	viability	CTAAACAGCACAATGCACCCTGG	PHF21A	ENSG00000135365	-0.009045139603007124	[79]	[239]	0	hSpCas9	negative selection	12412275
45971266	45971289	11	+	28162770	OCIAML3	viability	AGGTCTCTGGCCCACCACAGAGG	PHF21A	ENSG00000135365	0.3547670363206637	[42]	[165]	3	hSpCas9	negative selection	12412276
45971242	45971265	11	+	28162770	OCIAML3	viability	GATGGCGGTCACCATAGCAATGG	PHF21A	ENSG00000135365	0.7964518362340147	[36]	[193]	7	hSpCas9	negative selection	12412277
45965538	45965561	11	+	28162770	OCIAML3	viability	GGAGCTGCGAGCATGGGAGGTGG	PHF21A	ENSG00000135365	-1.731511164074098	[21]	[19]	-8	hSpCas9	negative selection	12412278
45965443	45965466	11	+	28162770	OCIAML3	viability	CATTGACGACACGGACGGGGTGG	PHF21A	ENSG00000135365	1.3878450129655773	[9]	[78]	9	hSpCas9	negative selection	12412279
45979780	45979803	11	+	28162770	OCIAML3	viability	GAGAGGCTGCAGCTGACTGCTGG	PHF21A	ENSG00000135365	0.40599235967583663	[40]	[163]	4	hSpCas9	negative selection	12412280
45965522	45965545	11	-	28162770	OCIAML3	viability	CAGCTCCTCAGCTTATCCAGAGG	PHF21A	ENSG00000135365	1.4754774599971208	[37]	[318]	9	hSpCas9	negative selection	12412281
45965390	45965413	11	+	28162770	OCIAML3	viability	AATGCTGGTGAGCTGGGCCATGG	PHF21A	ENSG00000135365	0.21334728173344109	[37]	[132]	2	hSpCas9	negative selection	12412282
45953538	45953561	11	-	28162770	OCIAML3	viability	TGCACCCAAACCAAAACGGGAGG	PHF21A	ENSG00000135365	-0.8570420461579571	[41]	[69]	-6	hSpCas9	negative selection	12412283