Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:5286
• Symbol:PIK3C2A
• Description:phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha

DataSource: http://genomecrispr.dkfz.de/#!/results/PIK3C2A

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
17169630	17169653	11	-	26472758	Jiyoye	viability	AGCATTACAGATGGAAGCAGAGG	PIK3C2A	ENSG00000011405	-0.07825144566436837	[41]	[29]	0	hSpCas9	negative selection	120668
17145918	17145941	11	-	26472758	Jiyoye	viability	AGAAGATGATGAAACACCCGTGG	PIK3C2A	ENSG00000011405	0.0188199248795351	[249]	[190]	0	hSpCas9	negative selection	120669
17094357	17094380	11	-	26472758	Jiyoye	viability	GTAGTCCGAATTTTGAGGGAAGG	PIK3C2A	ENSG00000011405	1.15867706882996	[78]	[132]	7	hSpCas9	negative selection	120670
17169716	17169739	11	-	26472758	Jiyoye	viability	GCTCAGATATCTAGCAACAGCGG	PIK3C2A	ENSG00000011405	0.8079286547784698	[202]	[267]	5	hSpCas9	negative selection	120671
17169581	17169604	11	-	26472758	Jiyoye	viability	CAAGTGACTGACAATCAGAGAGG	PIK3C2A	ENSG00000011405	-0.6412861074507717	[332]	[160]	-4	hSpCas9	negative selection	120672
17169348	17169371	11	+	26472758	Jiyoye	viability	AGAGCTGTGCTGAAAAGGAAGGG	PIK3C2A	ENSG00000011405	-0.05677171825391669	[39]	[28]	0	hSpCas9	negative selection	120673
17168886	17168909	11	-	26472758	Jiyoye	viability	GCCTAAGGTGGATAATGTGGAGG	PIK3C2A	ENSG00000011405	0.3835241134412283	[122]	[120]	3	hSpCas9	negative selection	120674
17168691	17168714	11	-	26472758	Jiyoye	viability	AACTCAGCTTGCAAAAGCCCAGG	PIK3C2A	ENSG00000011405	-0.23815973719476455	[121]	[77]	-2	hSpCas9	negative selection	120675
17155551	17155574	11	-	26472758	Jiyoye	viability	TGAAGTACAGAATGAGGAGATGG	PIK3C2A	ENSG00000011405	-0.32014004262661333	[148]	[89]	-2	hSpCas9	negative selection	120676
17150611	17150634	11	-	26472758	Jiyoye	viability	ACCAATCACCGCACAAACCCAGG	PIK3C2A	ENSG00000011405	0.6966819987008583	[8]	[10]	5	hSpCas9	negative selection	120677
17169630	17169653	11	-	26472758	KBM7	viability	AGCATTACAGATGGAAGCAGAGG	PIK3C2A	ENSG00000011405	0.13220232276385124	[252,199]	[117,113]	1	hSpCas9	negative selection	311786
17145918	17145941	11	-	26472758	KBM7	viability	AGAAGATGATGAAACACCCGTGG	PIK3C2A	ENSG00000011405	0.2575986521853836	[810,595]	[349,427]	2	hSpCas9	negative selection	311787
17094357	17094380	11	-	26472758	KBM7	viability	GTAGTCCGAATTTTGAGGGAAGG	PIK3C2A	ENSG00000011405	0.7474988532788034	[333,415]	[323,279]	7	hSpCas9	negative selection	311788
17169716	17169739	11	-	26472758	KBM7	viability	GCTCAGATATCTAGCAACAGCGG	PIK3C2A	ENSG00000011405	0.43805628495659865	[699,553]	[394,397]	5	hSpCas9	negative selection	311789
17169581	17169604	11	-	26472758	KBM7	viability	CAAGTGACTGACAATCAGAGAGG	PIK3C2A	ENSG00000011405	0.28379771865230863	[630,484]	[199,420]	3	hSpCas9	negative selection	311790
17169348	17169371	11	+	26472758	KBM7	viability	AGAGCTGTGCTGAAAAGGAAGGG	PIK3C2A	ENSG00000011405	-1.3048725436795419	[162,100]	[21,26]	-7	hSpCas9	negative selection	311791
17168886	17168909	11	-	26472758	KBM7	viability	GCCTAAGGTGGATAATGTGGAGG	PIK3C2A	ENSG00000011405	0.08424151663242913	[530,729]	[426,225]	0	hSpCas9	negative selection	311792
17168691	17168714	11	-	26472758	KBM7	viability	AACTCAGCTTGCAAAAGCCCAGG	PIK3C2A	ENSG00000011405	-0.22398276014498242	[258,304]	[123,106]	-2	hSpCas9	negative selection	311793
17155551	17155574	11	-	26472758	KBM7	viability	TGAAGTACAGAATGAGGAGATGG	PIK3C2A	ENSG00000011405	0.2805641654398106	[276,321]	[244,108]	3	hSpCas9	negative selection	311794
17150611	17150634	11	-	26472758	KBM7	viability	ACCAATCACCGCACAAACCCAGG	PIK3C2A	ENSG00000011405	-0.3612392635011199	[110,103]	[59,20]	-3	hSpCas9	negative selection	311795
17169630	17169653	11	-	26472758	Raji	viability	AGCATTACAGATGGAAGCAGAGG	PIK3C2A	ENSG00000011405	1.2751109811116659	[72]	[40]	9	hSpCas9	negative selection	502904
17145918	17145941	11	-	26472758	Raji	viability	AGAAGATGATGAAACACCCGTGG	PIK3C2A	ENSG00000011405	0.8135379824542772	[406]	[165]	7	hSpCas9	negative selection	502905
17094357	17094380	11	-	26472758	Raji	viability	GTAGTCCGAATTTTGAGGGAAGG	PIK3C2A	ENSG00000011405	0.915687911260068	[216]	[94]	8	hSpCas9	negative selection	502906
17169716	17169739	11	-	26472758	Raji	viability	GCTCAGATATCTAGCAACAGCGG	PIK3C2A	ENSG00000011405	1.0600778205952426	[247]	[119]	8	hSpCas9	negative selection	502907
17169581	17169604	11	-	26472758	Raji	viability	CAAGTGACTGACAATCAGAGAGG	PIK3C2A	ENSG00000011405	0.10738353537359951	[175]	[43]	1	hSpCas9	negative selection	502908
17169348	17169371	11	+	26472758	Raji	viability	AGAGCTGTGCTGAAAAGGAAGGG	PIK3C2A	ENSG00000011405	1.4293116302609619	[63]	[39]	9	hSpCas9	negative selection	502909
17168886	17168909	11	-	26472758	Raji	viability	GCCTAAGGTGGATAATGTGGAGG	PIK3C2A	ENSG00000011405	-0.14054397806998598	[398]	[83]	-1	hSpCas9	negative selection	502910
17168691	17168714	11	-	26472758	Raji	viability	AACTCAGCTTGCAAAAGCCCAGG	PIK3C2A	ENSG00000011405	0.7088341588833246	[115]	[43]	6	hSpCas9	negative selection	502911
17155551	17155574	11	-	26472758	Raji	viability	TGAAGTACAGAATGAGGAGATGG	PIK3C2A	ENSG00000011405	0.3105464852299948	[204]	[58]	3	hSpCas9	negative selection	502912
17150611	17150634	11	-	26472758	Raji	viability	ACCAATCACCGCACAAACCCAGG	PIK3C2A	ENSG00000011405	0.566815154010897	[31]	[10]	5	hSpCas9	negative selection	502913
17169630	17169653	11	-	26472758	K562	viability	AGCATTACAGATGGAAGCAGAGG	PIK3C2A	ENSG00000011405	0.4953125706280286	[178]	[212]	4	hSpCas9	negative selection	694022
17145918	17145941	11	-	26472758	K562	viability	AGAAGATGATGAAACACCCGTGG	PIK3C2A	ENSG00000011405	0.7361624004274173	[585]	[823]	6	hSpCas9	negative selection	694023
17094357	17094380	11	-	26472758	K562	viability	GTAGTCCGAATTTTGAGGGAAGG	PIK3C2A	ENSG00000011405	1.2467818650349276	[304]	[610]	9	hSpCas9	negative selection	694024
17169716	17169739	11	-	26472758	K562	viability	GCTCAGATATCTAGCAACAGCGG	PIK3C2A	ENSG00000011405	0.9342991857629118	[653]	[1054]	7	hSpCas9	negative selection	694025
17169581	17169604	11	-	26472758	K562	viability	CAAGTGACTGACAATCAGAGAGG	PIK3C2A	ENSG00000011405	0.13101733080735728	[462]	[427]	1	hSpCas9	negative selection	694026
17169348	17169371	11	+	26472758	K562	viability	AGAGCTGTGCTGAAAAGGAAGGG	PIK3C2A	ENSG00000011405	0.8654095375718169	[144]	[222]	7	hSpCas9	negative selection	694027
17168886	17168909	11	-	26472758	K562	viability	GCCTAAGGTGGATAATGTGGAGG	PIK3C2A	ENSG00000011405	0.4732374181623278	[575]	[674]	4	hSpCas9	negative selection	694028
17168691	17168714	11	-	26472758	K562	viability	AACTCAGCTTGCAAAAGCCCAGG	PIK3C2A	ENSG00000011405	0.12202209630672045	[208]	[191]	0	hSpCas9	negative selection	694029
17155551	17155574	11	-	26472758	K562	viability	TGAAGTACAGAATGAGGAGATGG	PIK3C2A	ENSG00000011405	-0.7266298986374241	[295]	[150]	-4	hSpCas9	negative selection	694030
17150611	17150634	11	-	26472758	K562	viability	ACCAATCACCGCACAAACCCAGG	PIK3C2A	ENSG00000011405	0.22754490910205072	[85]	[84]	1	hSpCas9	negative selection	694031
17119274	17119297	11	-	26627737	DLD1	viability	TAAGATCCCTAGCTGTGACCTGG	PIK3C2A	ENSG00000011405	0.33072255661095235	[274]	[173,89,65]	3	hSpCas9	negative selection	777769
17119830	17119853	11	-	26627737	DLD1	viability	CTTACTCATTGCTTCACCAGTGG	PIK3C2A	ENSG00000011405	0.5785707384187725	[781]	[210,535,356]	6	hSpCas9	negative selection	777770
17148731	17148754	11	+	26627737	DLD1	viability	AGTCATCATGTACCCAGCAAAGG	PIK3C2A	ENSG00000011405	0.1680929211829838	[868]	[226,431,267]	1	hSpCas9	negative selection	777771
17150611	17150634	11	-	26627737	DLD1	viability	ACCAATCACCGCACAAACCCAGG	PIK3C2A	ENSG00000011405	0.19936164606634	[845]	[267,354,291]	2	hSpCas9	negative selection	777772
17155595	17155618	11	-	26627737	DLD1	viability	GGGACCAGTAGTTTGCCAACTGG	PIK3C2A	ENSG00000011405	0.47347980681660107	[126]	[81,37,45]	5	hSpCas9	negative selection	777773
17169113	17169136	11	-	26627737	DLD1	viability	GCCACACCCTTTCATCCACAAGG	PIK3C2A	ENSG00000011405	1.240361953286043	[437]	[368,372,242]	9	hSpCas9	negative selection	777774
17119274	17119297	11	-	26627737	GBM cells	viability after 5 days	TAAGATCCCTAGCTGTGACCTGG	PIK3C2A	ENSG00000011405	0.004407003732999626	[144]	[80,74]	0	hSpCas9	negative selection	860084
17119830	17119853	11	-	26627737	GBM cells	viability after 5 days	CTTACTCATTGCTTCACCAGTGG	PIK3C2A	ENSG00000011405	0.2154458292121042	[374]	[235,230]	3	hSpCas9	negative selection	860085
17148731	17148754	11	+	26627737	GBM cells	viability after 5 days	AGTCATCATGTACCCAGCAAAGG	PIK3C2A	ENSG00000011405	-0.33723284169329687	[403]	[184,157]	-5	hSpCas9	negative selection	860086
17150611	17150634	11	-	26627737	GBM cells	viability after 5 days	ACCAATCACCGCACAAACCCAGG	PIK3C2A	ENSG00000011405	-0.04054458317926368	[559]	[349,233]	0	hSpCas9	negative selection	860087
17155595	17155618	11	-	26627737	GBM cells	viability after 5 days	GGGACCAGTAGTTTGCCAACTGG	PIK3C2A	ENSG00000011405	0.656057350989522	[70]	[78,40]	8	hSpCas9	negative selection	860088
17169113	17169136	11	-	26627737	GBM cells	viability after 5 days	GCCACACCCTTTCATCCACAAGG	PIK3C2A	ENSG00000011405	0.35196470010126074	[205]	[140,140]	5	hSpCas9	negative selection	860089
17119274	17119297	11	-	26627737	GBM cells	viability after 13 days	TAAGATCCCTAGCTGTGACCTGG	PIK3C2A	ENSG00000011405	-0.23298396538024457	[144]	[88,48]	-3	hSpCas9	negative selection	942399
17119830	17119853	11	-	26627737	GBM cells	viability after 13 days	CTTACTCATTGCTTCACCAGTGG	PIK3C2A	ENSG00000011405	0.15397402891121903	[374]	[232,220]	2	hSpCas9	negative selection	942400
17148731	17148754	11	+	26627737	GBM cells	viability after 13 days	AGTCATCATGTACCCAGCAAAGG	PIK3C2A	ENSG00000011405	-0.16714695984480854	[403]	[224,170]	-2	hSpCas9	negative selection	942401
17150611	17150634	11	-	26627737	GBM cells	viability after 13 days	ACCAATCACCGCACAAACCCAGG	PIK3C2A	ENSG00000011405	-0.4647115822916801	[559]	[212,225]	-5	hSpCas9	negative selection	942402
17155595	17155618	11	-	26627737	GBM cells	viability after 13 days	GGGACCAGTAGTTTGCCAACTGG	PIK3C2A	ENSG00000011405	0.6696865475259748	[70]	[68,54]	7	hSpCas9	negative selection	942403
17169113	17169136	11	-	26627737	GBM cells	viability after 13 days	GCCACACCCTTTCATCCACAAGG	PIK3C2A	ENSG00000011405	0.7020560353922424	[205]	[188,175]	8	hSpCas9	negative selection	942404
17119274	17119297	11	-	26627737	GBM cells	viability after 21 days	TAAGATCCCTAGCTGTGACCTGG	PIK3C2A	ENSG00000011405	-0.13421043714766356	[144]	[76,66]	-1	hSpCas9	negative selection	1024714
17119830	17119853	11	-	26627737	GBM cells	viability after 21 days	CTTACTCATTGCTTCACCAGTGG	PIK3C2A	ENSG00000011405	0.7259010164584598	[374]	[337,335]	7	hSpCas9	negative selection	1024715
17148731	17148754	11	+	26627737	GBM cells	viability after 21 days	AGTCATCATGTACCCAGCAAAGG	PIK3C2A	ENSG00000011405	-0.5694999409244309	[403]	[161,134]	-5	hSpCas9	negative selection	1024716
17150611	17150634	11	-	26627737	GBM cells	viability after 21 days	ACCAATCACCGCACAAACCCAGG	PIK3C2A	ENSG00000011405	-1.5325160230679153	[559]	[112,97]	-8	hSpCas9	negative selection	1024717
17155595	17155618	11	-	26627737	GBM cells	viability after 21 days	GGGACCAGTAGTTTGCCAACTGG	PIK3C2A	ENSG00000011405	1.4701542946570059	[70]	[109,103]	9	hSpCas9	negative selection	1024718
17169113	17169136	11	-	26627737	GBM cells	viability after 21 days	GCCACACCCTTTCATCCACAAGG	PIK3C2A	ENSG00000011405	0.3557323914227192	[205]	[149,136]	3	hSpCas9	negative selection	1024719
17119274	17119297	11	-	26627737	RPE1	viability after 9 days	TAAGATCCCTAGCTGTGACCTGG	PIK3C2A	ENSG00000011405	0.09465586358634037	[320]	[43,188]	0	hSpCas9	negative selection	1107029
17119830	17119853	11	-	26627737	RPE1	viability after 9 days	CTTACTCATTGCTTCACCAGTGG	PIK3C2A	ENSG00000011405	0.04180618337151598	[2091]	[709,627]	0	hSpCas9	negative selection	1107030
17148731	17148754	11	+	26627737	RPE1	viability after 9 days	AGTCATCATGTACCCAGCAAAGG	PIK3C2A	ENSG00000011405	0.5098811406352922	[1088]	[343,667]	3	hSpCas9	negative selection	1107031
17150611	17150634	11	-	26627737	RPE1	viability after 9 days	ACCAATCACCGCACAAACCCAGG	PIK3C2A	ENSG00000011405	-0.39702333935650047	[1596]	[318,457]	-3	hSpCas9	negative selection	1107032
17155595	17155618	11	-	26627737	RPE1	viability after 9 days	GGGACCAGTAGTTTGCCAACTGG	PIK3C2A	ENSG00000011405	0.41057496669863425	[393]	[173,150]	3	hSpCas9	negative selection	1107033
17169113	17169136	11	-	26627737	RPE1	viability after 9 days	GCCACACCCTTTCATCCACAAGG	PIK3C2A	ENSG00000011405	1.1600184516148697	[770]	[448,655]	7	hSpCas9	negative selection	1107034
17119274	17119297	11	-	26627737	RPE1	viability after 12 days	TAAGATCCCTAGCTGTGACCTGG	PIK3C2A	ENSG00000011405	-0.8696031209746864	[320]	[36,57]	-5	hSpCas9	negative selection	1189344
17119830	17119853	11	-	26627737	RPE1	viability after 12 days	CTTACTCATTGCTTCACCAGTGG	PIK3C2A	ENSG00000011405	-0.07610006300446948	[2091]	[691,364]	0	hSpCas9	negative selection	1189345
17148731	17148754	11	+	26627737	RPE1	viability after 12 days	AGTCATCATGTACCCAGCAAAGG	PIK3C2A	ENSG00000011405	0.27143127880300155	[1088]	[255,455]	1	hSpCas9	negative selection	1189346
17150611	17150634	11	-	26627737	RPE1	viability after 12 days	ACCAATCACCGCACAAACCCAGG	PIK3C2A	ENSG00000011405	-0.10913771979171305	[1596]	[339,458]	0	hSpCas9	negative selection	1189347
17155595	17155618	11	-	26627737	RPE1	viability after 12 days	GGGACCAGTAGTTTGCCAACTGG	PIK3C2A	ENSG00000011405	0.240503243910842	[393]	[177,68]	1	hSpCas9	negative selection	1189348
17169113	17169136	11	-	26627737	RPE1	viability after 12 days	GCCACACCCTTTCATCCACAAGG	PIK3C2A	ENSG00000011405	0.943598198938822	[770]	[309,491]	6	hSpCas9	negative selection	1189349
17119274	17119297	11	-	26627737	RPE1	viability after 15 days	TAAGATCCCTAGCTGTGACCTGG	PIK3C2A	ENSG00000011405	0.8325275519780189	[320]	[93,226]	5	hSpCas9	negative selection	1271659
17119830	17119853	11	-	26627737	RPE1	viability after 15 days	CTTACTCATTGCTTCACCAGTGG	PIK3C2A	ENSG00000011405	-0.2509627065945934	[2091]	[536,458]	-1	hSpCas9	negative selection	1271660
17148731	17148754	11	+	26627737	RPE1	viability after 15 days	AGTCATCATGTACCCAGCAAAGG	PIK3C2A	ENSG00000011405	-0.3092807290709918	[1088]	[185,308]	-2	hSpCas9	negative selection	1271661
17150611	17150634	11	-	26627737	RPE1	viability after 15 days	ACCAATCACCGCACAAACCCAGG	PIK3C2A	ENSG00000011405	-0.32815422476928213	[1596]	[283,432]	-2	hSpCas9	negative selection	1271662
17155595	17155618	11	-	26627737	RPE1	viability after 15 days	GGGACCAGTAGTTTGCCAACTGG	PIK3C2A	ENSG00000011405	0.7840304149069764	[393]	[280,105]	5	hSpCas9	negative selection	1271663
17169113	17169136	11	-	26627737	RPE1	viability after 15 days	GCCACACCCTTTCATCCACAAGG	PIK3C2A	ENSG00000011405	0.8997019201103958	[770]	[327,482]	5	hSpCas9	negative selection	1271664
17119274	17119297	11	-	26627737	RPE1	viability after 18 days	TAAGATCCCTAGCTGTGACCTGG	PIK3C2A	ENSG00000011405	-0.34387886411406887	[320]	[31,106]	-2	hSpCas9	negative selection	1353974
17119830	17119853	11	-	26627737	RPE1	viability after 18 days	CTTACTCATTGCTTCACCAGTGG	PIK3C2A	ENSG00000011405	0.025646137134869962	[2091]	[725,412]	0	hSpCas9	negative selection	1353975
17148731	17148754	11	+	26627737	RPE1	viability after 18 days	AGTCATCATGTACCCAGCAAAGG	PIK3C2A	ENSG00000011405	0.1593697814583409	[1088]	[348,305]	1	hSpCas9	negative selection	1353976
17150611	17150634	11	-	26627737	RPE1	viability after 18 days	ACCAATCACCGCACAAACCCAGG	PIK3C2A	ENSG00000011405	-0.17460648494460018	[1596]	[260,510]	-1	hSpCas9	negative selection	1353977
17155595	17155618	11	-	26627737	RPE1	viability after 18 days	GGGACCAGTAGTTTGCCAACTGG	PIK3C2A	ENSG00000011405	1.10592421903988	[393]	[384,61]	6	hSpCas9	negative selection	1353978
17169113	17169136	11	-	26627737	RPE1	viability after 18 days	GCCACACCCTTTCATCCACAAGG	PIK3C2A	ENSG00000011405	0.8245370762712128	[770]	[265,477]	5	hSpCas9	negative selection	1353979
17119274	17119297	11	-	26627737	HeLa	viability after 8 days	TAAGATCCCTAGCTGTGACCTGG	PIK3C2A	ENSG00000011405	2.753516744382396	[33]	[142,127,41]	9	hSpCas9	negative selection	1436289
17119830	17119853	11	-	26627737	HeLa	viability after 8 days	CTTACTCATTGCTTCACCAGTGG	PIK3C2A	ENSG00000011405	-0.7981113374241753	[646]	[336,139,54]	-7	hSpCas9	negative selection	1436290
17148731	17148754	11	+	26627737	HeLa	viability after 8 days	AGTCATCATGTACCCAGCAAAGG	PIK3C2A	ENSG00000011405	0.6379082283126024	[336]	[388,236,102]	5	hSpCas9	negative selection	1436291
17150611	17150634	11	-	26627737	HeLa	viability after 8 days	ACCAATCACCGCACAAACCCAGG	PIK3C2A	ENSG00000011405	-0.12639139867758287	[618]	[377,156,234]	-1	hSpCas9	negative selection	1436292
17155595	17155618	11	-	26627737	HeLa	viability after 8 days	GGGACCAGTAGTTTGCCAACTGG	PIK3C2A	ENSG00000011405	0.954142501793263	[66]	[113,9,57]	7	hSpCas9	negative selection	1436293
17169113	17169136	11	-	26627737	HeLa	viability after 8 days	GCCACACCCTTTCATCCACAAGG	PIK3C2A	ENSG00000011405	0.4557150820590621	[293]	[196,260,79]	4	hSpCas9	negative selection	1436294
17119274	17119297	11	-	26627737	HeLa	viability after 12 days	TAAGATCCCTAGCTGTGACCTGG	PIK3C2A	ENSG00000011405	2.441634523603271	[33]	[96,81,49]	9	hSpCas9	negative selection	1518604
17119830	17119853	11	-	26627737	HeLa	viability after 12 days	CTTACTCATTGCTTCACCAGTGG	PIK3C2A	ENSG00000011405	-0.5757440173079624	[646]	[73,274,175]	-5	hSpCas9	negative selection	1518605
17148731	17148754	11	+	26627737	HeLa	viability after 12 days	AGTCATCATGTACCCAGCAAAGG	PIK3C2A	ENSG00000011405	0.3631826539441576	[336]	[275,152,113]	3	hSpCas9	negative selection	1518606
17150611	17150634	11	-	26627737	HeLa	viability after 12 days	ACCAATCACCGCACAAACCCAGG	PIK3C2A	ENSG00000011405	0.1660450627575798	[618]	[304,348,200]	1	hSpCas9	negative selection	1518607
17155595	17155618	11	-	26627737	HeLa	viability after 12 days	GGGACCAGTAGTTTGCCAACTGG	PIK3C2A	ENSG00000011405	0.5674248537666495	[66]	[0,96,17]	5	hSpCas9	negative selection	1518608
17169113	17169136	11	-	26627737	HeLa	viability after 12 days	GCCACACCCTTTCATCCACAAGG	PIK3C2A	ENSG00000011405	0.5886317338381892	[293]	[189,119,244]	5	hSpCas9	negative selection	1518609
17119274	17119297	11	-	26627737	HeLa	viability after 15 days	TAAGATCCCTAGCTGTGACCTGG	PIK3C2A	ENSG00000011405	2.7179555675912694	[33]	[66,169,31]	9	hSpCas9	negative selection	1600919
17119830	17119853	11	-	26627737	HeLa	viability after 15 days	CTTACTCATTGCTTCACCAGTGG	PIK3C2A	ENSG00000011405	-0.3825658131381082	[646]	[174,198,234]	-3	hSpCas9	negative selection	1600920
17148731	17148754	11	+	26627737	HeLa	viability after 15 days	AGTCATCATGTACCCAGCAAAGG	PIK3C2A	ENSG00000011405	0.08290295292402086	[336]	[118,150,167]	0	hSpCas9	negative selection	1600921
17150611	17150634	11	-	26627737	HeLa	viability after 15 days	ACCAATCACCGCACAAACCCAGG	PIK3C2A	ENSG00000011405	-0.230676646119979	[618]	[320,93,228]	-2	hSpCas9	negative selection	1600922
17155595	17155618	11	-	26627737	HeLa	viability after 15 days	GGGACCAGTAGTTTGCCAACTGG	PIK3C2A	ENSG00000011405	1.2647512457424441	[66]	[26,105,63]	8	hSpCas9	negative selection	1600923
17169113	17169136	11	-	26627737	HeLa	viability after 15 days	GCCACACCCTTTCATCCACAAGG	PIK3C2A	ENSG00000011405	0.6661976434414969	[293]	[111,193,270]	5	hSpCas9	negative selection	1600924
17119274	17119297	11	-	26627737	HeLa	viability after 18 days	TAAGATCCCTAGCTGTGACCTGG	PIK3C2A	ENSG00000011405	2.7263497808888215	[33]	[44,141,31]	9	hSpCas9	negative selection	1683234
17119830	17119853	11	-	26627737	HeLa	viability after 18 days	CTTACTCATTGCTTCACCAGTGG	PIK3C2A	ENSG00000011405	-0.3673786884322994	[646]	[118,167,234]	-3	hSpCas9	negative selection	1683235
17148731	17148754	11	+	26627737	HeLa	viability after 18 days	AGTCATCATGTACCCAGCAAAGG	PIK3C2A	ENSG00000011405	0.030562040036048066	[336]	[72,120,167]	0	hSpCas9	negative selection	1683236
17150611	17150634	11	-	26627737	HeLa	viability after 18 days	ACCAATCACCGCACAAACCCAGG	PIK3C2A	ENSG00000011405	-0.1489362704319117	[618]	[237,79,228]	-1	hSpCas9	negative selection	1683237
17155595	17155618	11	-	26627737	HeLa	viability after 18 days	GGGACCAGTAGTTTGCCAACTGG	PIK3C2A	ENSG00000011405	1.3318283480592052	[66]	[19,92,63]	8	hSpCas9	negative selection	1683238
17169113	17169136	11	-	26627737	HeLa	viability after 18 days	GCCACACCCTTTCATCCACAAGG	PIK3C2A	ENSG00000011405	0.6714289150835893	[293]	[76,159,270]	5	hSpCas9	negative selection	1683239
17119274	17119297	11	-	26627737	HCT116	viability after 6 days	TAAGATCCCTAGCTGTGACCTGG	PIK3C2A	ENSG00000011405	-0.0072234720194466195	[394]	[142,16]	0	hSpCas9	negative selection	1765549
17119830	17119853	11	-	26627737	HCT116	viability after 6 days	CTTACTCATTGCTTCACCAGTGG	PIK3C2A	ENSG00000011405	0.07448050130167505	[1085]	[347,86]	0	hSpCas9	negative selection	1765550
17148731	17148754	11	+	26627737	HCT116	viability after 6 days	AGTCATCATGTACCCAGCAAAGG	PIK3C2A	ENSG00000011405	0.9670596232476498	[947]	[271,301]	5	hSpCas9	negative selection	1765551
17150611	17150634	11	-	26627737	HCT116	viability after 6 days	ACCAATCACCGCACAAACCCAGG	PIK3C2A	ENSG00000011405	0.9146720579102647	[1301]	[439,355]	5	hSpCas9	negative selection	1765552
17155595	17155618	11	-	26627737	HCT116	viability after 6 days	GGGACCAGTAGTTTGCCAACTGG	PIK3C2A	ENSG00000011405	2.0483349614802755	[112]	[135,38]	8	hSpCas9	negative selection	1765553
17169113	17169136	11	-	26627737	HCT116	viability after 6 days	GCCACACCCTTTCATCCACAAGG	PIK3C2A	ENSG00000011405	4.323634981095728	[99]	[395,269]	9	hSpCas9	negative selection	1765554
17119274	17119297	11	-	26627737	HCT116	viability after 8 days	TAAGATCCCTAGCTGTGACCTGG	PIK3C2A	ENSG00000011405	1.0741151878040123	[106]	[126,165,79]	8	hSpCas9	negative selection	1847864
17119830	17119853	11	-	26627737	HCT116	viability after 8 days	CTTACTCATTGCTTCACCAGTGG	PIK3C2A	ENSG00000011405	-0.6063986346167276	[817]	[338,422,128]	-6	hSpCas9	negative selection	1847865
17148731	17148754	11	+	26627737	HCT116	viability after 8 days	AGTCATCATGTACCCAGCAAAGG	PIK3C2A	ENSG00000011405	-0.12844859030830807	[444]	[229,213,228]	-1	hSpCas9	negative selection	1847866
17150611	17150634	11	-	26627737	HCT116	viability after 8 days	ACCAATCACCGCACAAACCCAGG	PIK3C2A	ENSG00000011405	0.7254803998596726	[309]	[320,243,282]	7	hSpCas9	negative selection	1847867
17155595	17155618	11	-	26627737	HCT116	viability after 8 days	GGGACCAGTAGTTTGCCAACTGG	PIK3C2A	ENSG00000011405	1.151320789884259	[60]	[127,27,68]	8	hSpCas9	negative selection	1847868
17169113	17169136	11	-	26627737	HCT116	viability after 8 days	GCCACACCCTTTCATCCACAAGG	PIK3C2A	ENSG00000011405	-0.14556683768205936	[249]	[137,123,111]	-2	hSpCas9	negative selection	1847869
17119274	17119297	11	-	26627737	HCT116	viability after 9 days	TAAGATCCCTAGCTGTGACCTGG	PIK3C2A	ENSG00000011405	-0.7280485735094858	[394]	[61,64]	-5	hSpCas9	negative selection	1930179
17119830	17119853	11	-	26627737	HCT116	viability after 9 days	CTTACTCATTGCTTCACCAGTGG	PIK3C2A	ENSG00000011405	-0.5542742649531099	[1085]	[335,87]	-4	hSpCas9	negative selection	1930180
17148731	17148754	11	+	26627737	HCT116	viability after 9 days	AGTCATCATGTACCCAGCAAAGG	PIK3C2A	ENSG00000011405	0.32925212812003113	[947]	[436,223]	2	hSpCas9	negative selection	1930181
17150611	17150634	11	-	26627737	HCT116	viability after 9 days	ACCAATCACCGCACAAACCCAGG	PIK3C2A	ENSG00000011405	0.22573149411397875	[1301]	[367,436]	1	hSpCas9	negative selection	1930182
17155595	17155618	11	-	26627737	HCT116	viability after 9 days	GGGACCAGTAGTTTGCCAACTGG	PIK3C2A	ENSG00000011405	0.4379179269389195	[112]	[84,5]	3	hSpCas9	negative selection	1930183
17169113	17169136	11	-	26627737	HCT116	viability after 9 days	GCCACACCCTTTCATCCACAAGG	PIK3C2A	ENSG00000011405	2.985432374105398	[99]	[330,116]	9	hSpCas9	negative selection	1930184
17119274	17119297	11	-	26627737	HCT116	viability after 12 days	TAAGATCCCTAGCTGTGACCTGG	PIK3C2A	ENSG00000011405	1.1400475404205457	[106]	[91,140,141]	8	hSpCas9	negative selection	2012494
17119830	17119853	11	-	26627737	HCT116	viability after 12 days	CTTACTCATTGCTTCACCAGTGG	PIK3C2A	ENSG00000011405	-0.26734758114944235	[817]	[417,350,296]	-3	hSpCas9	negative selection	2012495
17148731	17148754	11	+	26627737	HCT116	viability after 12 days	AGTCATCATGTACCCAGCAAAGG	PIK3C2A	ENSG00000011405	0.18759944721552657	[444]	[247,240,310]	2	hSpCas9	negative selection	2012496
17150611	17150634	11	-	26627737	HCT116	viability after 12 days	ACCAATCACCGCACAAACCCAGG	PIK3C2A	ENSG00000011405	0.5443225657127588	[309]	[279,277,151]	5	hSpCas9	negative selection	2012497
17155595	17155618	11	-	26627737	HCT116	viability after 12 days	GGGACCAGTAGTTTGCCAACTGG	PIK3C2A	ENSG00000011405	1.2038119633292272	[60]	[72,48,98]	8	hSpCas9	negative selection	2012498
17169113	17169136	11	-	26627737	HCT116	viability after 12 days	GCCACACCCTTTCATCCACAAGG	PIK3C2A	ENSG00000011405	0.6379022609685958	[249]	[271,229,105]	6	hSpCas9	negative selection	2012499
17119274	17119297	11	-	26627737	HCT116	viability after 15 days	TAAGATCCCTAGCTGTGACCTGG	PIK3C2A	ENSG00000011405	1.1645802801152938	[106]	[127,223,60]	8	hSpCas9	negative selection	2094809
17119830	17119853	11	-	26627737	HCT116	viability after 15 days	CTTACTCATTGCTTCACCAGTGG	PIK3C2A	ENSG00000011405	-0.7261354548110133	[817]	[240,343,261]	-6	hSpCas9	negative selection	2094810
17148731	17148754	11	+	26627737	HCT116	viability after 15 days	AGTCATCATGTACCCAGCAAAGG	PIK3C2A	ENSG00000011405	0.12784099861453513	[444]	[281,188,365]	1	hSpCas9	negative selection	2094811
17150611	17150634	11	-	26627737	HCT116	viability after 15 days	ACCAATCACCGCACAAACCCAGG	PIK3C2A	ENSG00000011405	0.8380497460160172	[309]	[380,312,268]	7	hSpCas9	negative selection	2094812
17155595	17155618	11	-	26627737	HCT116	viability after 15 days	GGGACCAGTAGTTTGCCAACTGG	PIK3C2A	ENSG00000011405	1.6716359366792024	[60]	[63,68,194]	9	hSpCas9	negative selection	2094813
17169113	17169136	11	-	26627737	HCT116	viability after 15 days	GCCACACCCTTTCATCCACAAGG	PIK3C2A	ENSG00000011405	0.09812936521025462	[249]	[197,161,106]	1	hSpCas9	negative selection	2094814
17119274	17119297	11	-	26627737	HCT116	viability after 18 days	TAAGATCCCTAGCTGTGACCTGG	PIK3C2A	ENSG00000011405	1.3364305195454738	[106]	[140,133,115]	8	hSpCas9	negative selection	2177124
17119830	17119853	11	-	26627737	HCT116	viability after 18 days	CTTACTCATTGCTTCACCAGTGG	PIK3C2A	ENSG00000011405	-0.5071681928661069	[817]	[281,265,287]	-4	hSpCas9	negative selection	2177125
17148731	17148754	11	+	26627737	HCT116	viability after 18 days	AGTCATCATGTACCCAGCAAAGG	PIK3C2A	ENSG00000011405	0.41702114393425993	[444]	[338,237,287]	3	hSpCas9	negative selection	2177126
17150611	17150634	11	-	26627737	HCT116	viability after 18 days	ACCAATCACCGCACAAACCCAGG	PIK3C2A	ENSG00000011405	1.4915278867585953	[309]	[452,538,256]	9	hSpCas9	negative selection	2177127
17155595	17155618	11	-	26627737	HCT116	viability after 18 days	GGGACCAGTAGTTTGCCAACTGG	PIK3C2A	ENSG00000011405	0.7805867639287627	[60]	[14,47,90]	6	hSpCas9	negative selection	2177128
17169113	17169136	11	-	26627737	HCT116	viability after 18 days	GCCACACCCTTTCATCCACAAGG	PIK3C2A	ENSG00000011405	0.6088017462762009	[249]	[253,120,181]	5	hSpCas9	negative selection	2177129
17169426	17169449	11	-	24336569	HL60	viability	TGAACTTGAGAAACTATTGCTGG	PIK3C2A	ENSG00000011405	0.268103674690527	[1095]	[2792]	2	hSpCas9	negative selection	2284086
17169432	17169455	11	+	24336569	HL60	viability	ATAGTTTCTCAAGTTCAGCTTGG	PIK3C2A	ENSG00000011405	0.6088514002384884	[263]	[851]	5	hSpCas9	negative selection	2284087
17169513	17169536	11	-	24336569	HL60	viability	CAAGCAGGATTATGATCTCATGG	PIK3C2A	ENSG00000011405	0.6932958490525919	[485]	[1662]	6	hSpCas9	negative selection	2284088
17169528	17169551	11	-	24336569	HL60	viability	AGCACAGGTTTATAACAAGCAGG	PIK3C2A	ENSG00000011405	-1.0447315495742922	[348]	[357]	-7	hSpCas9	negative selection	2284089
17169581	17169604	11	-	24336569	HL60	viability	CAAGTGACTGACAATCAGAGAGG	PIK3C2A	ENSG00000011405	-0.33264878858494634	[484]	[814]	-3	hSpCas9	negative selection	2284090
17169630	17169653	11	-	24336569	HL60	viability	AGCATTACAGATGGAAGCAGAGG	PIK3C2A	ENSG00000011405	1.1555750966719531	[398]	[1880]	8	hSpCas9	negative selection	2284091
17169639	17169662	11	-	24336569	HL60	viability	CAAAGAAGAAGCATTACAGATGG	PIK3C2A	ENSG00000011405	-1.7801954763076269	[210]	[129]	-9	hSpCas9	negative selection	2284092
17169680	17169703	11	+	24336569	HL60	viability	GTTGGTTCCGGATGTGAAGATGG	PIK3C2A	ENSG00000011405	-0.6021117878683389	[169]	[236]	-5	hSpCas9	negative selection	2284093
17169687	17169710	11	-	24336569	HL60	viability	AGAATGTCCATCTTCACATCCGG	PIK3C2A	ENSG00000011405	0.921373058674633	[507]	[2035]	7	hSpCas9	negative selection	2284094
17169716	17169739	11	-	24336569	HL60	viability	GCTCAGATATCTAGCAACAGCGG	PIK3C2A	ENSG00000011405	-0.941391217266828	[254]	[280]	-7	hSpCas9	negative selection	2284095
17169426	17169449	11	-	24336569	KBM7	viability	TGAACTTGAGAAACTATTGCTGG	PIK3C2A	ENSG00000011405	0.5253412693948333	[604]	[2374]	5	hSpCas9	negative selection	2351263
17169432	17169455	11	+	24336569	KBM7	viability	ATAGTTTCTCAAGTTCAGCTTGG	PIK3C2A	ENSG00000011405	-0.6699716178853304	[258]	[443]	-5	hSpCas9	negative selection	2351264
17169513	17169536	11	-	24336569	KBM7	viability	CAAGCAGGATTATGATCTCATGG	PIK3C2A	ENSG00000011405	-0.16536337751146862	[522]	[1271]	-1	hSpCas9	negative selection	2351265
17169528	17169551	11	-	24336569	KBM7	viability	AGCACAGGTTTATAACAAGCAGG	PIK3C2A	ENSG00000011405	2.0386051496941002	[135]	[1523]	9	hSpCas9	negative selection	2351266
17169581	17169604	11	-	24336569	KBM7	viability	CAAGTGACTGACAATCAGAGAGG	PIK3C2A	ENSG00000011405	-0.2934461671501619	[642]	[1430]	-2	hSpCas9	negative selection	2351267
17169630	17169653	11	-	24336569	KBM7	viability	AGCATTACAGATGGAAGCAGAGG	PIK3C2A	ENSG00000011405	0.2638246912032925	[483]	[1584]	2	hSpCas9	negative selection	2351268
17169639	17169662	11	-	24336569	KBM7	viability	CAAAGAAGAAGCATTACAGATGG	PIK3C2A	ENSG00000011405	-0.5731100786327414	[65]	[120]	-4	hSpCas9	negative selection	2351269
17169680	17169703	11	+	24336569	KBM7	viability	GTTGGTTCCGGATGTGAAGATGG	PIK3C2A	ENSG00000011405	0.09337612193318112	[232]	[677]	0	hSpCas9	negative selection	2351270
17169687	17169710	11	-	24336569	KBM7	viability	AGAATGTCCATCTTCACATCCGG	PIK3C2A	ENSG00000011405	0.2704760645091809	[406]	[1338]	2	hSpCas9	negative selection	2351271
17169716	17169739	11	-	24336569	KBM7	viability	GCTCAGATATCTAGCAACAGCGG	PIK3C2A	ENSG00000011405	1.5124227355191984	[31]	[248]	9	hSpCas9	negative selection	2351272
17077844	17077867	11	-	25494202	A375	resistance to PLX-4720 (puromycin)	ACCAAAGACCGATGCATGCCGGG	PIK3C2A	ENSG00000011405	2.6399830508724587	[69,94]	[190,30]	8	dCas9-VP64	positive selection	2389644
17077797	17077820	11	-	25494202	A375	resistance to PLX-4720 (puromycin)	GCGACGCTGAAATGCATTTCGGG	PIK3C2A	ENSG00000011405	-1.5329102460777078	[40,128]	[2,9]	-8	dCas9-VP64	positive selection	2389645
17077826	17077849	11	+	25494202	A375	resistance to PLX-4720 (puromycin)	TCGTCAATCCAGCCTCATCCCGG	PIK3C2A	ENSG00000011405	-1.4198614733292492	[220,78]	[7,14]	-7	dCas9-VP64	positive selection	2389646
17194791	17194814	11	+	25494202	A375	resistance to PLX-4720 (puromycin)	CCCAGCTACTCGGGAGTCTGAGG	PIK3C2A	ENSG00000011405	0.48846568775758525	[12,30]	[1,11]	2	dCas9-VP64	positive selection	2406187
17092628	17092651	11	-	25494202	A375	resistance to PLX-4720 (puromycin)	TGTCACCCAGGCTGGAGTGTAAG	PIK3C2A	ENSG00000011405	-0.8190118495057971	[36,422]	[11,46]	-4	dCas9-VP64	positive selection	2412781
17107158	17107181	11	+	25494202	A375	resistance to PLX-4720 (puromycin)	AAAAAATTAGCCGGGTGTCGTGG	PIK3C2A	ENSG00000011405	-0.26513306153968963	[62,264]	[7,53]	-1	dCas9-VP64	positive selection	2415302
17130907	17130930	11	-	25494202	A375	resistance to PLX-4720 (puromycin)	CAGGCGTGAGCCACCGCGTCTAG	PIK3C2A	ENSG00000011405	-0.7423063429264437	[17,121]	[9,7]	-4	dCas9-VP64	positive selection	2425679
17170019	17170042	11	+	25494202	A375	resistance to PLX-4720 (puromycin)	ACCCCATTTCCTGACACAACTGG	PIK3C2A	ENSG00000011405	1.4320516807716843	[69,56]	[65,7]	5	dCas9-VP64	positive selection	2430832
17169970	17169993	11	-	25494202	A375	resistance to PLX-4720 (puromycin)	CTGTAACCCAACAGTGTATAAGG	PIK3C2A	ENSG00000011405	-0.37000831817051655	[86,145]	[28,9]	-2	dCas9-VP64	positive selection	2430833
17169963	17169986	11	+	25494202	A375	resistance to PLX-4720 (puromycin)	CTTAACACCTTATACACTGTTGG	PIK3C2A	ENSG00000011405	0.6424802435809474	[275,480]	[161,96]	2	dCas9-VP64	positive selection	2430834
17109605	17109628	11	-	25494202	A375	resistance to PLX-4720 (puromycin)	CATGCTACTGCACTCCAACCCAG	PIK3C2A	ENSG00000011405	1.4182150241490903	[26,137]	[4,96]	5	dCas9-VP64	positive selection	2431900
17192099	17192122	11	+	25494202	A375	resistance to PLX-4720 (puromycin)	CGCACCACTGCACTCCAGCCAGG	PIK3C2A	ENSG00000011405	3.0347564003538725	[8,6]	[27,0]	8	dCas9-VP64	positive selection	2470836
17188295	17188318	11	+	25494202	A375	resistance to PLX-4720 (puromycin)	TGCACCACTACACTCCAACCTGG	PIK3C2A	ENSG00000011405	3.4470194688704208	[182,212]	[207,766]	9	dCas9-VP64	positive selection	2471454
17190030	17190053	11	+	25494202	A375	resistance to PLX-4720 (puromycin)	CAAGGTGGGTGGATCACTTGAGG	PIK3C2A	ENSG00000011405	2.670757623225415	[8,4]	[14,3]	8	dCas9-VP64	positive selection	2471821
17205356	17205379	11	+	25494202	A375	resistance to PLX-4720 (puromycin)	CCCAGCTCCTCGGGAGGCTGAGG	PIK3C2A	ENSG00000011405	-0.2571104693801929	[13,2]	[1,0]	-1	dCas9-VP64	positive selection	2474866
17077844	17077867	11	-	25494202	A375	resistance to PLX-4720 (zeocin)	ACCAAAGACCGATGCATGCCGGG	PIK3C2A	ENSG00000011405	-0.8766275828210419	[366,125]	[63,24]	-7	dCas9-VP64	positive selection	2484899
17077797	17077820	11	-	25494202	A375	resistance to PLX-4720 (zeocin)	GCGACGCTGAAATGCATTTCGGG	PIK3C2A	ENSG00000011405	-0.44958925329492616	[28,56]	[9,9]	-5	dCas9-VP64	positive selection	2484900
17077826	17077849	11	+	25494202	A375	resistance to PLX-4720 (zeocin)	TCGTCAATCCAGCCTCATCCCGG	PIK3C2A	ENSG00000011405	-0.8273677613843864	[187,188]	[33,34]	-7	dCas9-VP64	positive selection	2484901
17194791	17194814	11	+	25494202	A375	resistance to PLX-4720 (zeocin)	CCCAGCTACTCGGGAGTCTGAGG	PIK3C2A	ENSG00000011405	-0.014067359462650364	[104,52]	[22,26]	0	dCas9-VP64	positive selection	2501442
17092628	17092651	11	-	25494202	A375	resistance to PLX-4720 (zeocin)	TGTCACCCAGGCTGGAGTGTAAG	PIK3C2A	ENSG00000011405	-0.4049937477232412	[94,80]	[17,23]	-4	dCas9-VP64	positive selection	2508036
17107158	17107181	11	+	25494202	A375	resistance to PLX-4720 (zeocin)	AAAAAATTAGCCGGGTGTCGTGG	PIK3C2A	ENSG00000011405	0.8001190132117662	[123,184]	[163,14]	5	dCas9-VP64	positive selection	2510557
17130907	17130930	11	-	25494202	A375	resistance to PLX-4720 (zeocin)	CAGGCGTGAGCCACCGCGTCTAG	PIK3C2A	ENSG00000011405	0.04080549521603816	[105,72]	[24,33]	0	dCas9-VP64	positive selection	2520934
17170019	17170042	11	+	25494202	A375	resistance to PLX-4720 (zeocin)	ACCCCATTTCCTGACACAACTGG	PIK3C2A	ENSG00000011405	-0.1922138268611655	[134,185]	[50,39]	-2	dCas9-VP64	positive selection	2526087
17169970	17169993	11	-	25494202	A375	resistance to PLX-4720 (zeocin)	CTGTAACCCAACAGTGTATAAGG	PIK3C2A	ENSG00000011405	0.9776954956667988	[72,325]	[37,209]	6	dCas9-VP64	positive selection	2526088
17169963	17169986	11	+	25494202	A375	resistance to PLX-4720 (zeocin)	CTTAACACCTTATACACTGTTGG	PIK3C2A	ENSG00000011405	3.4791935790106705	[480,449]	[3251,243]	9	dCas9-VP64	positive selection	2526089
17109605	17109628	11	-	25494202	A375	resistance to PLX-4720 (zeocin)	CATGCTACTGCACTCCAACCCAG	PIK3C2A	ENSG00000011405	-0.7695084672536312	[174,39]	[21,18]	-7	dCas9-VP64	positive selection	2527155
17192099	17192122	11	+	25494202	A375	resistance to PLX-4720 (zeocin)	CGCACCACTGCACTCCAGCCAGG	PIK3C2A	ENSG00000011405	0.038175304513698105	[60,77]	[26,18]	0	dCas9-VP64	positive selection	2566091
17188295	17188318	11	+	25494202	A375	resistance to PLX-4720 (zeocin)	TGCACCACTACACTCCAACCTGG	PIK3C2A	ENSG00000011405	0.6976192756297284	[195,233]	[93,131]	5	dCas9-VP64	positive selection	2566709
17190030	17190053	11	+	25494202	A375	resistance to PLX-4720 (zeocin)	CAAGGTGGGTGGATCACTTGAGG	PIK3C2A	ENSG00000011405	0.9990680086899741	[19,33]	[6,26]	6	dCas9-VP64	positive selection	2567076
17205356	17205379	11	+	25494202	A375	resistance to PLX-4720 (zeocin)	CCCAGCTCCTCGGGAGGCTGAGG	PIK3C2A	ENSG00000011405	0.5230605474514848	[120,26]	[20,47]	4	dCas9-VP64	positive selection	2570121
17169426	17169449	11	-	27260157	DLD1	viability	TGAACTTGAGAAACTATTGCTGG	PIK3C2A	ENSG00000011405	-0.16171574876648	[]	[]	-1	hSpCas9	negative selection	2574480
17169680	17169703	11	+	27260157	DLD1	viability	GTTGGTTCCGGATGTGAAGATGG	PIK3C2A	ENSG00000011405	0.168405153990359	[]	[]	3	hSpCas9	negative selection	2576846
17169368	17169391	11	+	27260157	DLD1	viability	GGGCTCAGAATAGGAGTAACTGG	PIK3C2A	ENSG00000011405	-0.58228611635546	[]	[]	-5	hSpCas9	negative selection	2579481
17169083	17169106	11	+	27260157	DLD1	viability	CTGACTACTGGACGATAGATAGG	PIK3C2A	ENSG00000011405	0.300403566133226	[]	[]	4	hSpCas9	negative selection	2579603
17169281	17169304	11	+	27260157	DLD1	viability	AAAGCATAAGTGGAAGGCCCAGG	PIK3C2A	ENSG00000011405	-0.613650789279105	[]	[]	-5	hSpCas9	negative selection	2582313
17169298	17169321	11	-	27260157	DLD1	viability	AGTGGCCACCTGGATTACCTGGG	PIK3C2A	ENSG00000011405	0.662718317091262	[]	[]	8	hSpCas9	negative selection	2586618
17169630	17169653	11	-	27260157	DLD1	viability	AGCATTACAGATGGAAGCAGAGG	PIK3C2A	ENSG00000011405	-0.244904367188111	[]	[]	-2	hSpCas9	negative selection	2586728
17169113	17169136	11	-	27260157	DLD1	viability	GCCACACCCTTTCATCCACAAGG	PIK3C2A	ENSG00000011405	0.583695616704079	[]	[]	8	hSpCas9	negative selection	2604887
17169513	17169536	11	-	27260157	DLD1	viability	CAAGCAGGATTATGATCTCATGG	PIK3C2A	ENSG00000011405	0.594472472199335	[]	[]	8	hSpCas9	negative selection	2606254
17169528	17169551	11	-	27260157	DLD1	viability	AGCACAGGTTTATAACAAGCAGG	PIK3C2A	ENSG00000011405	-0.40044064004653	[]	[]	-3	hSpCas9	negative selection	2612684
17169581	17169604	11	-	27260157	DLD1	viability	CAAGTGACTGACAATCAGAGAGG	PIK3C2A	ENSG00000011405	0.460409330618163	[]	[]	8	hSpCas9	negative selection	2614740
17169317	17169340	11	+	27260157	DLD1	viability	CACTGTCCTCTCTGAATAGTAGG	PIK3C2A	ENSG00000011405	0.157850584130617	[]	[]	3	hSpCas9	negative selection	2616901
17169308	17169331	11	-	27260157	DLD1	viability	CAGAGAGGACAGTGGCCACCTGG	PIK3C2A	ENSG00000011405	0.0916412104127189	[]	[]	3	hSpCas9	negative selection	2617254
17169687	17169710	11	-	27260157	DLD1	viability	AGAATGTCCATCTTCACATCCGG	PIK3C2A	ENSG00000011405	0.0159783345417508	[]	[]	0	hSpCas9	negative selection	2620638
17169071	17169094	11	+	27260157	DLD1	viability	GCCATGTCAGTACTGACTACTGG	PIK3C2A	ENSG00000011405	0.418409072256496	[]	[]	7	hSpCas9	negative selection	2622621
17169125	17169148	11	+	27260157	DLD1	viability	AAGGGTGTGGCAGGTGTCAAAGG	PIK3C2A	ENSG00000011405	-0.529774544205333	[]	[]	-4	hSpCas9	negative selection	2641387
17169716	17169739	11	-	27260157	DLD1	viability	GCTCAGATATCTAGCAACAGCGG	PIK3C2A	ENSG00000011405	-0.829526477297324	[]	[]	-6	hSpCas9	negative selection	2644111
17169639	17169662	11	-	27260157	DLD1	viability	CAAAGAAGAAGCATTACAGATGG	PIK3C2A	ENSG00000011405	0.335628575701819	[]	[]	4	hSpCas9	negative selection	2647125
17169432	17169455	11	+	27260157	DLD1	viability	ATAGTTTCTCAAGTTCAGCTTGG	PIK3C2A	ENSG00000011405	-0.336942278920314	[]	[]	-3	hSpCas9	negative selection	2648544
17169072	17169095	11	-	27260157	DLD1	viability	TCCAGTAGTCAGTACTGACATGG	PIK3C2A	ENSG00000011405	0.14482958526063	[]	[]	3	hSpCas9	negative selection	2648602
17169426	17169449	11	-	27260157	HT1080	viability	TGAACTTGAGAAACTATTGCTGG	PIK3C2A	ENSG00000011405	0.628985381946782	[]	[]	5	hSpCas9	negative selection	2650610
17169680	17169703	11	+	27260157	HT1080	viability	GTTGGTTCCGGATGTGAAGATGG	PIK3C2A	ENSG00000011405	-0.898231090282156	[]	[]	-8	hSpCas9	negative selection	2652976
17169368	17169391	11	+	27260157	HT1080	viability	GGGCTCAGAATAGGAGTAACTGG	PIK3C2A	ENSG00000011405	-0.336271241198729	[]	[]	-7	hSpCas9	negative selection	2655611
17169083	17169106	11	+	27260157	HT1080	viability	CTGACTACTGGACGATAGATAGG	PIK3C2A	ENSG00000011405	-0.177030807085462	[]	[]	0	hSpCas9	negative selection	2655733
17169281	17169304	11	+	27260157	HT1080	viability	AAAGCATAAGTGGAAGGCCCAGG	PIK3C2A	ENSG00000011405	0.0675486287970832	[]	[]	0	hSpCas9	negative selection	2658443
17169298	17169321	11	-	27260157	HT1080	viability	AGTGGCCACCTGGATTACCTGGG	PIK3C2A	ENSG00000011405	1.11791231676257	[]	[]	8	hSpCas9	negative selection	2662748
17169630	17169653	11	-	27260157	HT1080	viability	AGCATTACAGATGGAAGCAGAGG	PIK3C2A	ENSG00000011405	0.145826025194922	[]	[]	1	hSpCas9	negative selection	2662858
17169113	17169136	11	-	27260157	HT1080	viability	GCCACACCCTTTCATCCACAAGG	PIK3C2A	ENSG00000011405	0.984048435429457	[]	[]	8	hSpCas9	negative selection	2681017
17169513	17169536	11	-	27260157	HT1080	viability	CAAGCAGGATTATGATCTCATGG	PIK3C2A	ENSG00000011405	1.02273267047556	[]	[]	8	hSpCas9	negative selection	2682384
17169528	17169551	11	-	27260157	HT1080	viability	AGCACAGGTTTATAACAAGCAGG	PIK3C2A	ENSG00000011405	-0.181197979117502	[]	[]	0	hSpCas9	negative selection	2688814
17169581	17169604	11	-	27260157	HT1080	viability	CAAGTGACTGACAATCAGAGAGG	PIK3C2A	ENSG00000011405	0.354247372385083	[]	[]	3	hSpCas9	negative selection	2690870
17169317	17169340	11	+	27260157	HT1080	viability	CACTGTCCTCTCTGAATAGTAGG	PIK3C2A	ENSG00000011405	-1.10689657024564	[]	[]	-8	hSpCas9	negative selection	2693031
17169308	17169331	11	-	27260157	HT1080	viability	CAGAGAGGACAGTGGCCACCTGG	PIK3C2A	ENSG00000011405	0.503166597508768	[]	[]	4	hSpCas9	negative selection	2693384
17169687	17169710	11	-	27260157	HT1080	viability	AGAATGTCCATCTTCACATCCGG	PIK3C2A	ENSG00000011405	0.552769367045986	[]	[]	5	hSpCas9	negative selection	2696768
17169071	17169094	11	+	27260157	HT1080	viability	GCCATGTCAGTACTGACTACTGG	PIK3C2A	ENSG00000011405	-0.407711395721316	[]	[]	-7	hSpCas9	negative selection	2698751
17169125	17169148	11	+	27260157	HT1080	viability	AAGGGTGTGGCAGGTGTCAAAGG	PIK3C2A	ENSG00000011405	-0.330725041850325	[]	[]	-7	hSpCas9	negative selection	2717517
17169716	17169739	11	-	27260157	HT1080	viability	GCTCAGATATCTAGCAACAGCGG	PIK3C2A	ENSG00000011405	-0.297803994307809	[]	[]	-7	hSpCas9	negative selection	2720241
17169639	17169662	11	-	27260157	HT1080	viability	CAAAGAAGAAGCATTACAGATGG	PIK3C2A	ENSG00000011405	1.68903277741247	[]	[]	9	hSpCas9	negative selection	2723255
17169432	17169455	11	+	27260157	HT1080	viability	ATAGTTTCTCAAGTTCAGCTTGG	PIK3C2A	ENSG00000011405	0.471534930994067	[]	[]	4	hSpCas9	negative selection	2724674
17169072	17169095	11	-	27260157	HT1080	viability	TCCAGTAGTCAGTACTGACATGG	PIK3C2A	ENSG00000011405	-0.674086370772407	[]	[]	-8	hSpCas9	negative selection	2724732
17169426	17169449	11	-	27260157	MKN45	viability	TGAACTTGAGAAACTATTGCTGG	PIK3C2A	ENSG00000011405	-0.470850325307958	[]	[]	-6	hSpCas9	negative selection	2726740
17169680	17169703	11	+	27260157	MKN45	viability	GTTGGTTCCGGATGTGAAGATGG	PIK3C2A	ENSG00000011405	0.0997774443837422	[]	[]	0	hSpCas9	negative selection	2729106
17169368	17169391	11	+	27260157	MKN45	viability	GGGCTCAGAATAGGAGTAACTGG	PIK3C2A	ENSG00000011405	0.211569043399795	[]	[]	5	hSpCas9	negative selection	2731741
17169083	17169106	11	+	27260157	MKN45	viability	CTGACTACTGGACGATAGATAGG	PIK3C2A	ENSG00000011405	0.528380409447296	[]	[]	6	hSpCas9	negative selection	2731863
17169281	17169304	11	+	27260157	MKN45	viability	AAAGCATAAGTGGAAGGCCCAGG	PIK3C2A	ENSG00000011405	0.534427696281884	[]	[]	6	hSpCas9	negative selection	2734573
17169298	17169321	11	-	27260157	MKN45	viability	AGTGGCCACCTGGATTACCTGGG	PIK3C2A	ENSG00000011405	1.63579240983857	[]	[]	9	hSpCas9	negative selection	2738878
17169630	17169653	11	-	27260157	MKN45	viability	AGCATTACAGATGGAAGCAGAGG	PIK3C2A	ENSG00000011405	0.683845446234181	[]	[]	7	hSpCas9	negative selection	2738988
17169113	17169136	11	-	27260157	MKN45	viability	GCCACACCCTTTCATCCACAAGG	PIK3C2A	ENSG00000011405	1.17049451111793	[]	[]	8	hSpCas9	negative selection	2757147
17169513	17169536	11	-	27260157	MKN45	viability	CAAGCAGGATTATGATCTCATGG	PIK3C2A	ENSG00000011405	0.330741556578205	[]	[]	6	hSpCas9	negative selection	2758514
17169528	17169551	11	-	27260157	MKN45	viability	AGCACAGGTTTATAACAAGCAGG	PIK3C2A	ENSG00000011405	-0.625181510979485	[]	[]	-6	hSpCas9	negative selection	2764944
17169581	17169604	11	-	27260157	MKN45	viability	CAAGTGACTGACAATCAGAGAGG	PIK3C2A	ENSG00000011405	0.805879667369253	[]	[]	7	hSpCas9	negative selection	2767000
17169317	17169340	11	+	27260157	MKN45	viability	CACTGTCCTCTCTGAATAGTAGG	PIK3C2A	ENSG00000011405	-0.101080615705192	[]	[]	0	hSpCas9	negative selection	2769161
17169308	17169331	11	-	27260157	MKN45	viability	CAGAGAGGACAGTGGCCACCTGG	PIK3C2A	ENSG00000011405	0.159074686917794	[]	[]	5	hSpCas9	negative selection	2769514
17169687	17169710	11	-	27260157	MKN45	viability	AGAATGTCCATCTTCACATCCGG	PIK3C2A	ENSG00000011405	0.289520780091097	[]	[]	5	hSpCas9	negative selection	2772898
17169071	17169094	11	+	27260157	MKN45	viability	GCCATGTCAGTACTGACTACTGG	PIK3C2A	ENSG00000011405	0.351402643855247	[]	[]	6	hSpCas9	negative selection	2774881
17169125	17169148	11	+	27260157	MKN45	viability	AAGGGTGTGGCAGGTGTCAAAGG	PIK3C2A	ENSG00000011405	0.215487441919958	[]	[]	5	hSpCas9	negative selection	2793647
17169716	17169739	11	-	27260157	MKN45	viability	GCTCAGATATCTAGCAACAGCGG	PIK3C2A	ENSG00000011405	-0.498342484263138	[]	[]	-6	hSpCas9	negative selection	2796371
17169639	17169662	11	-	27260157	MKN45	viability	CAAAGAAGAAGCATTACAGATGG	PIK3C2A	ENSG00000011405	1.49117107123633	[]	[]	9	hSpCas9	negative selection	2799385
17169432	17169455	11	+	27260157	MKN45	viability	ATAGTTTCTCAAGTTCAGCTTGG	PIK3C2A	ENSG00000011405	0.733405640097356	[]	[]	7	hSpCas9	negative selection	2800804
17169072	17169095	11	-	27260157	MKN45	viability	TCCAGTAGTCAGTACTGACATGG	PIK3C2A	ENSG00000011405	0.139285309578877	[]	[]	5	hSpCas9	negative selection	2800862
17169426	17169449	11	-	27260157	RKO	viability	TGAACTTGAGAAACTATTGCTGG	PIK3C2A	ENSG00000011405	-0.118738710407788	[]	[]	0	hSpCas9	negative selection	2802870
17169680	17169703	11	+	27260157	RKO	viability	GTTGGTTCCGGATGTGAAGATGG	PIK3C2A	ENSG00000011405	0.927560559153727	[]	[]	8	hSpCas9	negative selection	2805236
17169368	17169391	11	+	27260157	RKO	viability	GGGCTCAGAATAGGAGTAACTGG	PIK3C2A	ENSG00000011405	-0.105342456134977	[]	[]	0	hSpCas9	negative selection	2807871
17169083	17169106	11	+	27260157	RKO	viability	CTGACTACTGGACGATAGATAGG	PIK3C2A	ENSG00000011405	-0.116032431882326	[]	[]	0	hSpCas9	negative selection	2807993
17169281	17169304	11	+	27260157	RKO	viability	AAAGCATAAGTGGAAGGCCCAGG	PIK3C2A	ENSG00000011405	0.161450921127874	[]	[]	0	hSpCas9	negative selection	2810703
17169298	17169321	11	-	27260157	RKO	viability	AGTGGCCACCTGGATTACCTGGG	PIK3C2A	ENSG00000011405	1.22828158535641	[]	[]	9	hSpCas9	negative selection	2815008
17169630	17169653	11	-	27260157	RKO	viability	AGCATTACAGATGGAAGCAGAGG	PIK3C2A	ENSG00000011405	0.134119862645025	[]	[]	0	hSpCas9	negative selection	2815118
17169113	17169136	11	-	27260157	RKO	viability	GCCACACCCTTTCATCCACAAGG	PIK3C2A	ENSG00000011405	0.931369484236429	[]	[]	8	hSpCas9	negative selection	2833277
17169513	17169536	11	-	27260157	RKO	viability	CAAGCAGGATTATGATCTCATGG	PIK3C2A	ENSG00000011405	-0.327519868141025	[]	[]	-6	hSpCas9	negative selection	2834644
17169528	17169551	11	-	27260157	RKO	viability	AGCACAGGTTTATAACAAGCAGG	PIK3C2A	ENSG00000011405	-0.531612204010977	[]	[]	-6	hSpCas9	negative selection	2841074
17169581	17169604	11	-	27260157	RKO	viability	CAAGTGACTGACAATCAGAGAGG	PIK3C2A	ENSG00000011405	0.413709493944102	[]	[]	2	hSpCas9	negative selection	2843130
17169317	17169340	11	+	27260157	RKO	viability	CACTGTCCTCTCTGAATAGTAGG	PIK3C2A	ENSG00000011405	-0.0273426339098945	[]	[]	0	hSpCas9	negative selection	2845291
17169308	17169331	11	-	27260157	RKO	viability	CAGAGAGGACAGTGGCCACCTGG	PIK3C2A	ENSG00000011405	0.276508352740033	[]	[]	1	hSpCas9	negative selection	2845644
17169687	17169710	11	-	27260157	RKO	viability	AGAATGTCCATCTTCACATCCGG	PIK3C2A	ENSG00000011405	0.527599534351869	[]	[]	3	hSpCas9	negative selection	2849028
17169071	17169094	11	+	27260157	RKO	viability	GCCATGTCAGTACTGACTACTGG	PIK3C2A	ENSG00000011405	-0.0964229329143151	[]	[]	0	hSpCas9	negative selection	2851011
17169125	17169148	11	+	27260157	RKO	viability	AAGGGTGTGGCAGGTGTCAAAGG	PIK3C2A	ENSG00000011405	-0.753783610612551	[]	[]	-7	hSpCas9	negative selection	2869777
17169716	17169739	11	-	27260157	RKO	viability	GCTCAGATATCTAGCAACAGCGG	PIK3C2A	ENSG00000011405	0.0633895933620112	[]	[]	0	hSpCas9	negative selection	2872501
17169639	17169662	11	-	27260157	RKO	viability	CAAAGAAGAAGCATTACAGATGG	PIK3C2A	ENSG00000011405	1.09744480716679	[]	[]	9	hSpCas9	negative selection	2875515
17169432	17169455	11	+	27260157	RKO	viability	ATAGTTTCTCAAGTTCAGCTTGG	PIK3C2A	ENSG00000011405	0.810097425377473	[]	[]	8	hSpCas9	negative selection	2876934
17169072	17169095	11	-	27260157	RKO	viability	TCCAGTAGTCAGTACTGACATGG	PIK3C2A	ENSG00000011405	-1.20889308488688	[]	[]	-8	hSpCas9	negative selection	2876992
17169426	17169449	11	-	27260157	SF268	viability	TGAACTTGAGAAACTATTGCTGG	PIK3C2A	ENSG00000011405	-0.0215930200625911	[]	[]	0	hSpCas9	negative selection	2879000
17169680	17169703	11	+	27260157	SF268	viability	GTTGGTTCCGGATGTGAAGATGG	PIK3C2A	ENSG00000011405	0.923610505085667	[]	[]	9	hSpCas9	negative selection	2881366
17169368	17169391	11	+	27260157	SF268	viability	GGGCTCAGAATAGGAGTAACTGG	PIK3C2A	ENSG00000011405	-0.222887994899654	[]	[]	-2	hSpCas9	negative selection	2884001
17169083	17169106	11	+	27260157	SF268	viability	CTGACTACTGGACGATAGATAGG	PIK3C2A	ENSG00000011405	0.132548081597812	[]	[]	0	hSpCas9	negative selection	2884123
17169281	17169304	11	+	27260157	SF268	viability	AAAGCATAAGTGGAAGGCCCAGG	PIK3C2A	ENSG00000011405	0.497278167996396	[]	[]	7	hSpCas9	negative selection	2886833
17169298	17169321	11	-	27260157	SF268	viability	AGTGGCCACCTGGATTACCTGGG	PIK3C2A	ENSG00000011405	1.28933088248358	[]	[]	9	hSpCas9	negative selection	2891138
17169630	17169653	11	-	27260157	SF268	viability	AGCATTACAGATGGAAGCAGAGG	PIK3C2A	ENSG00000011405	0.0788820357989697	[]	[]	0	hSpCas9	negative selection	2891248
17169113	17169136	11	-	27260157	SF268	viability	GCCACACCCTTTCATCCACAAGG	PIK3C2A	ENSG00000011405	0.677459829456116	[]	[]	8	hSpCas9	negative selection	2909407
17169513	17169536	11	-	27260157	SF268	viability	CAAGCAGGATTATGATCTCATGG	PIK3C2A	ENSG00000011405	-0.915255087814201	[]	[]	-6	hSpCas9	negative selection	2910774
17169528	17169551	11	-	27260157	SF268	viability	AGCACAGGTTTATAACAAGCAGG	PIK3C2A	ENSG00000011405	0.103681363042312	[]	[]	0	hSpCas9	negative selection	2917204
17169581	17169604	11	-	27260157	SF268	viability	CAAGTGACTGACAATCAGAGAGG	PIK3C2A	ENSG00000011405	0.196242802880499	[]	[]	3	hSpCas9	negative selection	2919260
17169317	17169340	11	+	27260157	SF268	viability	CACTGTCCTCTCTGAATAGTAGG	PIK3C2A	ENSG00000011405	-0.400181265376938	[]	[]	-3	hSpCas9	negative selection	2921421
17169308	17169331	11	-	27260157	SF268	viability	CAGAGAGGACAGTGGCCACCTGG	PIK3C2A	ENSG00000011405	1.40109424165375	[]	[]	9	hSpCas9	negative selection	2921774
17169687	17169710	11	-	27260157	SF268	viability	AGAATGTCCATCTTCACATCCGG	PIK3C2A	ENSG00000011405	0.333568387976069	[]	[]	4	hSpCas9	negative selection	2925158
17169071	17169094	11	+	27260157	SF268	viability	GCCATGTCAGTACTGACTACTGG	PIK3C2A	ENSG00000011405	-0.281938274518058	[]	[]	-2	hSpCas9	negative selection	2927141
17169125	17169148	11	+	27260157	SF268	viability	AAGGGTGTGGCAGGTGTCAAAGG	PIK3C2A	ENSG00000011405	0.162360087717317	[]	[]	0	hSpCas9	negative selection	2945907
17169716	17169739	11	-	27260157	SF268	viability	GCTCAGATATCTAGCAACAGCGG	PIK3C2A	ENSG00000011405	0.243531215469082	[]	[]	3	hSpCas9	negative selection	2948631
17169639	17169662	11	-	27260157	SF268	viability	CAAAGAAGAAGCATTACAGATGG	PIK3C2A	ENSG00000011405	0.612613939519292	[]	[]	8	hSpCas9	negative selection	2951645
17169432	17169455	11	+	27260157	SF268	viability	ATAGTTTCTCAAGTTCAGCTTGG	PIK3C2A	ENSG00000011405	0.427669729253579	[]	[]	4	hSpCas9	negative selection	2953064
17169072	17169095	11	-	27260157	SF268	viability	TCCAGTAGTCAGTACTGACATGG	PIK3C2A	ENSG00000011405	-0.60715607878024	[]	[]	-5	hSpCas9	negative selection	2953122
17131997	17132020	11	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	ATATGTTCACTGTCTCACAATGG	PIK3C2A	ENSG00000011405	-0.5643251010684853	[3,3]	[2,1]	-7	hSpCas9	positive selection	3011351
17169113	17169136	11	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCCACACCCTTTCATCCACAAGG	PIK3C2A	ENSG00000011405	0.17299382977996458	[5,5]	[5,4]	3	hSpCas9	positive selection	3011352
17169716	17169739	11	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCTCAGATATCTAGCAACAGCGG	PIK3C2A	ENSG00000011405	-0.5457099254557585	[3,2]	[1,1]	-7	hSpCas9	positive selection	3011353
17155581	17155604	11	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TGAAGAAGAGAACTTCCAGTTGG	PIK3C2A	ENSG00000011405	-0.12593901627264947	[3,3]	[1,3]	-2	hSpCas9	positive selection	3011354
17131997	17132020	11	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	ATATGTTCACTGTCTCACAATGG	PIK3C2A	ENSG00000011405	-0.42415464343003206	[3,3]	[3,0]	-6	hSpCas9	positive selection	3079209
17169113	17169136	11	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCCACACCCTTTCATCCACAAGG	PIK3C2A	ENSG00000011405	0.2314250259968137	[5,5]	[6,3]	4	hSpCas9	positive selection	3079210
17169716	17169739	11	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCTCAGATATCTAGCAACAGCGG	PIK3C2A	ENSG00000011405	0.11334480058621038	[3,3]	[3,1]	2	hSpCas9	positive selection	3079211
17155581	17155604	11	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TGAAGAAGAGAACTTCCAGTTGG	PIK3C2A	ENSG00000011405	0.8249294636703649	[3,3]	[2,6]	9	hSpCas9	positive selection	3079212
17150611	17150634		-	24336571	A375	resistance to PLX after 7 days	ACCAATCACCGCACAAACCCAGG	PIK3C2A	ENSG00000011405	-0.20970754100761746	[5,7]	[5,5]	-6	hSpCas9	positive selection	3135603
17150497	17150520		+	24336571	A375	resistance to PLX after 7 days	CCATCACACGTAAAAGTAACTGG	PIK3C2A	ENSG00000011405	-0.8811856549920358	[4,5]	[1,2]	-9	hSpCas9	positive selection	3135604
17145705	17145728		+	24336571	A375	resistance to PLX after 7 days	GAATCTAAGAGTTCTTCAACAGG	PIK3C2A	ENSG00000011405	0.29336769364622295	[8,6]	[8,9]	7	hSpCas9	positive selection	3135605
17145673	17145696		+	24336571	A375	resistance to PLX after 7 days	TTTGAAGAGCCAGTTCTACTTGG	PIK3C2A	ENSG00000011405	-0.21809155205314967	[35,34]	[32,27]	-6	hSpCas9	positive selection	3135606
17150611	17150634		-	24336571	A375	resistance to PLX after 14 days	ACCAATCACCGCACAAACCCAGG	PIK3C2A	ENSG00000011405	-0.5480805600579036	[6,7]	[1,1]	-6	hSpCas9	positive selection	3193396
17150497	17150520		+	24336571	A375	resistance to PLX after 14 days	CCATCACACGTAAAAGTAACTGG	PIK3C2A	ENSG00000011405	-0.6011790261753784	[5,5]	[1,1]	-7	hSpCas9	positive selection	3193397
17145705	17145728		+	24336571	A375	resistance to PLX after 14 days	GAATCTAAGAGTTCTTCAACAGG	PIK3C2A	ENSG00000011405	1.4245285895627289	[10,11]	[15,11]	8	hSpCas9	positive selection	3193398
17145673	17145696		+	24336571	A375	resistance to PLX after 14 days	TTTGAAGAGCCAGTTCTACTTGG	PIK3C2A	ENSG00000011405	-0.39741168661246307	[40,28]	[9,13]	-5	hSpCas9	positive selection	3193399
17150611	17150634		-	24336571	A375	viability after 7 days	ACCAATCACCGCACAAACCCAGG	PIK3C2A	ENSG00000011405	-1.1969811421820873	[16]	[5,7]	-9	hSpCas9	negative selection	3251189
17150497	17150520		+	24336571	A375	viability after 7 days	CCATCACACGTAAAAGTAACTGG	PIK3C2A	ENSG00000011405	-0.12947340912050342	[5]	[4,5]	-2	hSpCas9	negative selection	3251190
17145705	17145728		+	24336571	A375	viability after 7 days	GAATCTAAGAGTTCTTCAACAGG	PIK3C2A	ENSG00000011405	-0.39044384545647975	[10]	[8,6]	-5	hSpCas9	negative selection	3251191
17145673	17145696		+	24336571	A375	viability after 7 days	TTTGAAGAGCCAGTTCTACTTGG	PIK3C2A	ENSG00000011405	0.41773352916424633	[27]	[35,34]	6	hSpCas9	negative selection	3251192
17150611	17150634		-	24336571	A375	viability after 14 days	ACCAATCACCGCACAAACCCAGG	PIK3C2A	ENSG00000011405	-1.0753942790719226	[16]	[6,7]	-8	hSpCas9	negative selection	3308982
17150497	17150520		+	24336571	A375	viability after 14 days	CCATCACACGTAAAAGTAACTGG	PIK3C2A	ENSG00000011405	0.014941083146217338	[5]	[5,5]	0	hSpCas9	negative selection	3308983
17145705	17145728		+	24336571	A375	viability after 14 days	GAATCTAAGAGTTCTTCAACAGG	PIK3C2A	ENSG00000011405	0.12756868516861464	[10]	[10,11]	1	hSpCas9	negative selection	3308984
17145673	17145696		+	24336571	A375	viability after 14 days	TTTGAAGAGCCAGTTCTACTTGG	PIK3C2A	ENSG00000011405	0.41865614794093164	[27]	[40,28]	5	hSpCas9	negative selection	3308985
17145682	17145705	11	-	27383988	293T	resistance to West Nile virus (flavivirus)	TTATCACAACCAAGTAGAACTGG	PIK3C2A	ENSG00000011405	-1.032692635486783	[312,312]	[0,0]	-7	hSpCas9	positive selection	3385867
17112618	17112641	11	-	27383988	293T	resistance to West Nile virus (flavivirus)	TGTCCCCCTAAAAGTCACAATGG	PIK3C2A	ENSG00000011405	-0.3351308258222454	[192,192]	[0,0]	-2	hSpCas9	positive selection	3385868
17112637	17112660	11	+	27383988	293T	resistance to West Nile virus (flavivirus)	GACAGCATTAGAACTGAAGAAGG	PIK3C2A	ENSG00000011405	1.3265888738829488	[60,60]	[0,0]	6	hSpCas9	positive selection	3385869
17131997	17132020	11	-	26780180	HT29	viability (Avana library 4 designs)	ATATGTTCACTGTCTCACAATGG	PIK3C2A	ENSG00000011405	1.84417895300808	[]	[]	7	hSpCas9	negative selection	3449434
17169113	17169136	11	-	26780180	HT29	viability (Avana library 4 designs)	GCCACACCCTTTCATCCACAAGG	PIK3C2A	ENSG00000011405	-0.00297421652185983	[]	[]	0	hSpCas9	negative selection	3449435
17169716	17169739	11	-	26780180	HT29	viability (Avana library 4 designs)	GCTCAGATATCTAGCAACAGCGG	PIK3C2A	ENSG00000011405	0.051520245568681	[]	[]	0	hSpCas9	negative selection	3449436
17155580	17155603	11	+	26780180	HT29	viability (Avana library 4 designs)	TGAAGAAGAGAACTTCCAGTTGG	PIK3C2A	ENSG00000011405	1.37521885078788	[]	[]	5	hSpCas9	negative selection	3449437
17169716	17169739	11	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCTCAGATATCTAGCAACAGCGG	PIK3C2A	ENSG00000011405	3.04793820011062	[]	[]	5	hSpCas9	negative selection	3544195
17155580	17155603	11	+	26780180	A375	viability (Avana lentiCRISPRv2)	TGAAGAAGAGAACTTCCAGTTGG	PIK3C2A	ENSG00000011405	-1.95412958675658	[]	[]	-2	hSpCas9	negative selection	3544196
17169113	17169136	11	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCCACACCCTTTCATCCACAAGG	PIK3C2A	ENSG00000011405	2.24248109547191	[]	[]	3	hSpCas9	negative selection	3544197
17131997	17132020	11	-	26780180	A375	viability (Avana lentiCRISPRv2)	ATATGTTCACTGTCTCACAATGG	PIK3C2A	ENSG00000011405	-6.91500908111842	[]	[]	-6	hSpCas9	negative selection	3544198
17169581	17169604	11	-	26780180	A375	viability (Avana lentiCRISPRv2)	CAAGTGACTGACAATCAGAGAGG	PIK3C2A	ENSG00000011405	0.468023442976329	[]	[]	0	hSpCas9	negative selection	3544199
17169191	17169214	11	+	26780180	A375	viability (Avana lentiCRISPRv2)	GGTTCTGTAGATGGAAAAGTGGG	PIK3C2A	ENSG00000011405	2.53065913299192	[]	[]	4	hSpCas9	negative selection	3544200
17169716	17169739	11	-	26780180	A375	viability (Avana lentiGuide)	GCTCAGATATCTAGCAACAGCGG	PIK3C2A	ENSG00000011405	1.4591006928099	[]	[]	1	hSpCas9	negative selection	3652854
17155580	17155603	11	+	26780180	A375	viability (Avana lentiGuide)	TGAAGAAGAGAACTTCCAGTTGG	PIK3C2A	ENSG00000011405	-0.204432045956222	[]	[]	0	hSpCas9	negative selection	3652855
17169113	17169136	11	-	26780180	A375	viability (Avana lentiGuide)	GCCACACCCTTTCATCCACAAGG	PIK3C2A	ENSG00000011405	-4.87797058640229	[]	[]	-8	hSpCas9	negative selection	3652856
17131997	17132020	11	-	26780180	A375	viability (Avana lentiGuide)	ATATGTTCACTGTCTCACAATGG	PIK3C2A	ENSG00000011405	0.586438951368725	[]	[]	0	hSpCas9	negative selection	3652857
17169581	17169604	11	-	26780180	A375	viability (Avana lentiGuide)	CAAGTGACTGACAATCAGAGAGG	PIK3C2A	ENSG00000011405	-1.81036205147686	[]	[]	-3	hSpCas9	negative selection	3652858
17169191	17169214	11	+	26780180	A375	viability (Avana lentiGuide)	GGTTCTGTAGATGGAAAAGTGGG	PIK3C2A	ENSG00000011405	-0.0796893473046352	[]	[]	0	hSpCas9	negative selection	3652859
17169716	17169739	11	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCTCAGATATCTAGCAACAGCGG	PIK3C2A	ENSG00000011405	0.03197249135667006	[4]	[4,4]	0	hSpCas9	positive selection	3761513
17155580	17155603	11	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TGAAGAAGAGAACTTCCAGTTGG	PIK3C2A	ENSG00000011405	-0.7879104965792644	[5]	[4,1]	-8	hSpCas9	positive selection	3761514
17169113	17169136	11	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCCACACCCTTTCATCCACAAGG	PIK3C2A	ENSG00000011405	-0.02495138965411106	[6]	[6,5]	0	hSpCas9	positive selection	3761515
17131997	17132020	11	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ATATGTTCACTGTCTCACAATGG	PIK3C2A	ENSG00000011405	-0.2877083506529769	[6]	[4,5]	-4	hSpCas9	positive selection	3761516
17169581	17169604	11	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CAAGTGACTGACAATCAGAGAGG	PIK3C2A	ENSG00000011405	-0.0015355334509642993	[4]	[5,3]	0	hSpCas9	positive selection	3761517
17169191	17169214	11	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGTTCTGTAGATGGAAAAGTGGG	PIK3C2A	ENSG00000011405	-0.10605246280375505	[5]	[5,3]	-2	hSpCas9	positive selection	3761518
17169716	17169739	11	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCTCAGATATCTAGCAACAGCGG	PIK3C2A	ENSG00000011405	0.30790796480645255	[4]	[5,3]	8	hSpCas9	positive selection	3870120
17155580	17155603	11	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TGAAGAAGAGAACTTCCAGTTGG	PIK3C2A	ENSG00000011405	-0.12186311279063781	[5]	[4,3]	-2	hSpCas9	positive selection	3870121
17169113	17169136	11	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCCACACCCTTTCATCCACAAGG	PIK3C2A	ENSG00000011405	0.29227184332329437	[7]	[7,7]	7	hSpCas9	positive selection	3870122
17131997	17132020	11	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ATATGTTCACTGTCTCACAATGG	PIK3C2A	ENSG00000011405	0.2088680993243667	[5]	[5,5]	5	hSpCas9	positive selection	3870123
17169581	17169604	11	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CAAGTGACTGACAATCAGAGAGG	PIK3C2A	ENSG00000011405	-0.6722924788040459	[4]	[0,3]	-7	hSpCas9	positive selection	3870124
17169191	17169214	11	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGTTCTGTAGATGGAAAAGTGGG	PIK3C2A	ENSG00000011405	0.3252071456152926	[6]	[7,6]	8	hSpCas9	positive selection	3870125
17150611	17150634	11	-	26780180	A375	viability	ACCAATCACCGCACAAACCCAGG	PIK3C2A	ENSG00000011405	1.28519687827156	[]	[]	7	hSpCas9	negative selection	3980927
17150497	17150520	11	+	26780180	A375	viability	CCATCACACGTAAAAGTAACTGG	PIK3C2A	ENSG00000011405	1.14414407774752	[]	[]	6	hSpCas9	negative selection	3980928
17112637	17112660	11	+	26780180	A375	viability	GACAGCATTAGAACTGAAGAAGG	PIK3C2A	ENSG00000011405	0.796654735038774	[]	[]	3	hSpCas9	negative selection	3980929
17112618	17112641	11	-	26780180	A375	viability	TGTCCCCCTAAAAGTCACAATGG	PIK3C2A	ENSG00000011405	0.960718798856908	[]	[]	4	hSpCas9	negative selection	3980930
17145682	17145705	11	-	26780180	A375	viability	TTATCACAACCAAGTAGAACTGG	PIK3C2A	ENSG00000011405	0.974967529796409	[]	[]	4	hSpCas9	negative selection	3980931
17145673	17145696	11	+	26780180	A375	viability	TTTGAAGAGCCAGTTCTACTTGG	PIK3C2A	ENSG00000011405	-0.726414956423671	[]	[]	-9	hSpCas9	negative selection	3980932
17150611	17150634	11	-	26780180	HT29	viability (GeCKOv2 library)	ACCAATCACCGCACAAACCCAGG	PIK3C2A	ENSG00000011405	1.62289407901753	[]	[]	8	hSpCas9	negative selection	4088893
17150497	17150520	11	+	26780180	HT29	viability (GeCKOv2 library)	CCATCACACGTAAAAGTAACTGG	PIK3C2A	ENSG00000011405	1.69788247362116	[]	[]	8	hSpCas9	negative selection	4088894
17112637	17112660	11	+	26780180	HT29	viability (GeCKOv2 library)	GACAGCATTAGAACTGAAGAAGG	PIK3C2A	ENSG00000011405	0.74195571122818	[]	[]	3	hSpCas9	negative selection	4088895
17112618	17112641	11	-	26780180	HT29	viability (GeCKOv2 library)	TGTCCCCCTAAAAGTCACAATGG	PIK3C2A	ENSG00000011405	0.776136759190361	[]	[]	3	hSpCas9	negative selection	4088896
17145682	17145705	11	-	26780180	HT29	viability (GeCKOv2 library)	TTATCACAACCAAGTAGAACTGG	PIK3C2A	ENSG00000011405	1.19421757214128	[]	[]	6	hSpCas9	negative selection	4088897
17145673	17145696	11	+	26780180	HT29	viability (GeCKOv2 library)	TTTGAAGAGCCAGTTCTACTTGG	PIK3C2A	ENSG00000011405	-0.0977251852321938	[]	[]	-3	hSpCas9	negative selection	4088898
17150611	17150634	11	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	ACCAATCACCGCACAAACCCAGG	PIK3C2A	ENSG00000011405	-0.5116325902256088	[3]	[1,0]	-8	hSpCas9	positive selection	4160556
17150497	17150520	11	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CCATCACACGTAAAAGTAACTGG	PIK3C2A	ENSG00000011405	-0.3881724682800938	[1]	[0,0]	-7	hSpCas9	positive selection	4160557
17145705	17145728	11	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GAATCTAAGAGTTCTTCAACAGG	PIK3C2A	ENSG00000011405	0.3177919052618087	[2]	[0,3]	7	hSpCas9	positive selection	4160558
17145673	17145696	11	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TTTGAAGAGCCAGTTCTACTTGG	PIK3C2A	ENSG00000011405	0.20331392354800165	[4]	[3,3]	5	hSpCas9	positive selection	4160559
17150611	17150634	11	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	ACCAATCACCGCACAAACCCAGG	PIK3C2A	ENSG00000011405	0.7024195641945956	[3]	[4,2,4,0]	4	hSpCas9	positive selection	4224578
17150497	17150520	11	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CCATCACACGTAAAAGTAACTGG	PIK3C2A	ENSG00000011405	0.6377021107690604	[2]	[0,0,0,2]	4	hSpCas9	positive selection	4224579
17145705	17145728	11	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GAATCTAAGAGTTCTTCAACAGG	PIK3C2A	ENSG00000011405	0.4289546631420969	[3]	[4,2,2,0]	3	hSpCas9	positive selection	4224580
17145673	17145696	11	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TTTGAAGAGCCAGTTCTACTTGG	PIK3C2A	ENSG00000011405	1.3138370459767315	[4]	[5,4,5,4]	9	hSpCas9	positive selection	4224581
17150497	17150520	11	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCATCACACGTAAAAGTAACTGG	PIK3C2A	ENSG00000011405	-0.5040956734755467	[2]	[1,0]	-8	hSpCas9	positive selection	4290270
17150611	17150634	11	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ACCAATCACCGCACAAACCCAGG	PIK3C2A	ENSG00000011405	0.010138343467936906	[4]	[4,2]	0	hSpCas9	positive selection	4290271
17145673	17145696	11	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TTTGAAGAGCCAGTTCTACTTGG	PIK3C2A	ENSG00000011405	0.46447649694809723	[4]	[5,5]	8	hSpCas9	positive selection	4290272
17145682	17145705	11	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TTATCACAACCAAGTAGAACTGG	PIK3C2A	ENSG00000011405	-0.3619345623566511	[3]	[3,0]	-6	hSpCas9	positive selection	4354522
17112618	17112641	11	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TGTCCCCCTAAAAGTCACAATGG	PIK3C2A	ENSG00000011405	0.12086202107529631	[2]	[2,1]	2	hSpCas9	positive selection	4354523
17112637	17112660	11	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GACAGCATTAGAACTGAAGAAGG	PIK3C2A	ENSG00000011405	1.2771336285074968	[1]	[1,4]	9	hSpCas9	positive selection	4354524
17135110	17135132	11	-	27760321	OCIAML3	viability	CTAGCAGGAGTTCAACTAGGGG	PIK3C2A	ENSG00000011405	0.028789640591309174	[340,230]	[187,273]	0	hSpCas9	negative selection	4427821
17145851	17145873	11	+	27760321	OCIAML3	viability	TAGATGATATACCTCGTCATGG	PIK3C2A	ENSG00000011405	0.7562309868163719	[76,64]	[46,153]	8	hSpCas9	negative selection	4427822
17168901	17168923	11	-	27760321	OCIAML3	viability	GATCCTCTAAGTAAGCCTAAGG	PIK3C2A	ENSG00000011405	-0.26092230192014365	[136,113]	[81,80]	-3	hSpCas9	negative selection	4427823
17169072	17169094	11	+	27760321	OCIAML3	viability	CCATGTCAGTACTGACTACTGG	PIK3C2A	ENSG00000011405	-0.3176780585145289	[262,198]	[171,106]	-3	hSpCas9	negative selection	4427824
17169323	17169345	11	-	27760321	OCIAML3	viability	TTAGACCTACTATTCAGAGAGG	PIK3C2A	ENSG00000011405	-0.17649982085571514	[38,29]	[24,21]	-2	hSpCas9	negative selection	4427825
17135110	17135132	11	-	27760321	OCIAML2	viability	CTAGCAGGAGTTCAACTAGGGG	PIK3C2A	ENSG00000011405	-0.09978045482759823	[340,230]	[245,169]	-1	hSpCas9	negative selection	4511284
17145851	17145873	11	+	27760321	OCIAML2	viability	TAGATGATATACCTCGTCATGG	PIK3C2A	ENSG00000011405	0.4401740024825984	[76,64]	[87,63]	6	hSpCas9	negative selection	4511285
17168901	17168923	11	-	27760321	OCIAML2	viability	GATCCTCTAAGTAAGCCTAAGG	PIK3C2A	ENSG00000011405	0.3398299467028223	[136,113]	[114,144]	4	hSpCas9	negative selection	4511286
17169072	17169094	11	+	27760321	OCIAML2	viability	CCATGTCAGTACTGACTACTGG	PIK3C2A	ENSG00000011405	-0.7385775730599806	[262,198]	[76,155]	-7	hSpCas9	negative selection	4511287
17169323	17169345	11	-	27760321	OCIAML2	viability	TTAGACCTACTATTCAGAGAGG	PIK3C2A	ENSG00000011405	0.3589219880243948	[38,29]	[41,26]	5	hSpCas9	negative selection	4511288
17135110	17135132	11	-	27760321	MV411	viability	CTAGCAGGAGTTCAACTAGGGG	PIK3C2A	ENSG00000011405	-1.0962419114971893	[340,230]	[53,136]	-6	hSpCas9	negative selection	4594747
17145851	17145873	11	+	27760321	MV411	viability	TAGATGATATACCTCGTCATGG	PIK3C2A	ENSG00000011405	2.6555506211281554	[76,64]	[457,47]	9	hSpCas9	negative selection	4594748
17168901	17168923	11	-	27760321	MV411	viability	GATCCTCTAAGTAAGCCTAAGG	PIK3C2A	ENSG00000011405	-0.025888005868240027	[136,113]	[80,80]	0	hSpCas9	negative selection	4594749
17169072	17169094	11	+	27760321	MV411	viability	CCATGTCAGTACTGACTACTGG	PIK3C2A	ENSG00000011405	0.7986180818576856	[262,198]	[274,244]	6	hSpCas9	negative selection	4594750
17169323	17169345	11	-	27760321	MV411	viability	TTAGACCTACTATTCAGAGAGG	PIK3C2A	ENSG00000011405	1.7028606913861557	[38,29]	[31,135]	9	hSpCas9	negative selection	4594751
17135110	17135132	11	-	27760321	HL60	viability	CTAGCAGGAGTTCAACTAGGGG	PIK3C2A	ENSG00000011405	-1.2394593061904442	[340,230]	[54,142]	-8	hSpCas9	negative selection	4678210
17145851	17145873	11	+	27760321	HL60	viability	TAGATGATATACCTCGTCATGG	PIK3C2A	ENSG00000011405	-0.3959738386169387	[76,64]	[7,81]	-4	hSpCas9	negative selection	4678211
17168901	17168923	11	-	27760321	HL60	viability	GATCCTCTAAGTAAGCCTAAGG	PIK3C2A	ENSG00000011405	-0.5892556404235167	[136,113]	[62,72]	-6	hSpCas9	negative selection	4678212
17169072	17169094	11	+	27760321	HL60	viability	CCATGTCAGTACTGACTACTGG	PIK3C2A	ENSG00000011405	-2.0893428982673585	[262,198]	[59,26]	-9	hSpCas9	negative selection	4678213
17169323	17169345	11	-	27760321	HL60	viability	TTAGACCTACTATTCAGAGAGG	PIK3C2A	ENSG00000011405	-0.32339952971494235	[38,29]	[0,44]	-4	hSpCas9	negative selection	4678214
17135110	17135132	11	-	27760321	HT1080	viability	CTAGCAGGAGTTCAACTAGGGG	PIK3C2A	ENSG00000011405	-0.3371598714064308	[230,179]	[49,80]	-1	hSpCas9	negative selection	4761673
17145851	17145873	11	+	27760321	HT1080	viability	TAGATGATATACCTCGTCATGG	PIK3C2A	ENSG00000011405	-4.530637787261012	[64,50]	[0,0]	-8	hSpCas9	negative selection	4761674
17168901	17168923	11	-	27760321	HT1080	viability	GATCCTCTAAGTAAGCCTAAGG	PIK3C2A	ENSG00000011405	0.5454376956133811	[113,88]	[111,0]	3	hSpCas9	negative selection	4761675
17169072	17169094	11	+	27760321	HT1080	viability	CCATGTCAGTACTGACTACTGG	PIK3C2A	ENSG00000011405	-2.125539718525301	[198,154]	[29,0]	-6	hSpCas9	negative selection	4761676
17169323	17169345	11	-	27760321	HT1080	viability	TTAGACCTACTATTCAGAGAGG	PIK3C2A	ENSG00000011405	-3.429279739642115	[29,23]	[0,0]	-7	hSpCas9	negative selection	4761677
17135110	17135132	11	-	27760321	HT29	viability after 7 days	CTAGCAGGAGTTCAACTAGGGG	PIK3C2A	ENSG00000011405	-0.12066041447669706	[230,179]	[262,273,195]	-2	hSpCas9	negative selection	4845136
17145851	17145873	11	+	27760321	HT29	viability after 7 days	TAGATGATATACCTCGTCATGG	PIK3C2A	ENSG00000011405	-0.7512483336708615	[64,50]	[66,20,47]	-8	hSpCas9	negative selection	4845137
17168901	17168923	11	-	27760321	HT29	viability after 7 days	GATCCTCTAAGTAAGCCTAAGG	PIK3C2A	ENSG00000011405	0.2661450331405557	[113,88]	[220,173,86]	4	hSpCas9	negative selection	4845138
17169072	17169094	11	+	27760321	HT29	viability after 7 days	CCATGTCAGTACTGACTACTGG	PIK3C2A	ENSG00000011405	0.1870893194672929	[198,154]	[182,198,379]	3	hSpCas9	negative selection	4845139
17169323	17169345	11	-	27760321	HT29	viability after 7 days	TTAGACCTACTATTCAGAGAGG	PIK3C2A	ENSG00000011405	-0.6717279255131583	[29,23]	[8,44,9]	-7	hSpCas9	negative selection	4845140
17135110	17135132	11	-	27760321	HT29	viability after 25 days	CTAGCAGGAGTTCAACTAGGGG	PIK3C2A	ENSG00000011405	0.016715210739094433	[230,179]	[201,210,308]	0	hSpCas9	negative selection	4928599
17145851	17145873	11	+	27760321	HT29	viability after 25 days	TAGATGATATACCTCGTCATGG	PIK3C2A	ENSG00000011405	-0.5193244310897556	[64,50]	[15,31,97]	-5	hSpCas9	negative selection	4928600
17168901	17168923	11	-	27760321	HT29	viability after 25 days	GATCCTCTAAGTAAGCCTAAGG	PIK3C2A	ENSG00000011405	0.05723576225442217	[113,88]	[146,85,127]	0	hSpCas9	negative selection	4928601
17169072	17169094	11	+	27760321	HT29	viability after 25 days	CCATGTCAGTACTGACTACTGG	PIK3C2A	ENSG00000011405	0.16347747262089485	[198,154]	[60,243,402]	1	hSpCas9	negative selection	4928602
17169323	17169345	11	-	27760321	HT29	viability after 25 days	TTAGACCTACTATTCAGAGAGG	PIK3C2A	ENSG00000011405	-4.948962004488639	[29,23]	[0,0,0]	-9	hSpCas9	negative selection	4928603
17135110	17135132	11	-	27760321	HT29	viability after 22 days	CTAGCAGGAGTTCAACTAGGGG	PIK3C2A	ENSG00000011405	0.2887758629813941	[230,179]	[509,231,120]	3	hSpCas9	negative selection	5012062
17145851	17145873	11	+	27760321	HT29	viability after 22 days	TAGATGATATACCTCGTCATGG	PIK3C2A	ENSG00000011405	-0.061643882031449326	[64,50]	[91,40,58]	0	hSpCas9	negative selection	5012063
17168901	17168923	11	-	27760321	HT29	viability after 22 days	GATCCTCTAAGTAAGCCTAAGG	PIK3C2A	ENSG00000011405	0.8069821315544137	[113,88]	[394,192,20]	8	hSpCas9	negative selection	5012064
17169072	17169094	11	+	27760321	HT29	viability after 22 days	CCATGTCAGTACTGACTACTGG	PIK3C2A	ENSG00000011405	-0.068697251306848	[198,154]	[86,217,283]	0	hSpCas9	negative selection	5012065
17169323	17169345	11	-	27760321	HT29	viability after 22 days	TTAGACCTACTATTCAGAGAGG	PIK3C2A	ENSG00000011405	-4.217215876864478	[29,23]	[2,0,0]	-9	hSpCas9	negative selection	5012066
17135110	17135132	11	-	27760321	HT29	viability after 19 days	CTAGCAGGAGTTCAACTAGGGG	PIK3C2A	ENSG00000011405	0.8572366893476332	[230,179]	[168,547,528]	8	hSpCas9	negative selection	5095525
17145851	17145873	11	+	27760321	HT29	viability after 19 days	TAGATGATATACCTCGTCATGG	PIK3C2A	ENSG00000011405	-0.3468243317336204	[64,50]	[63,21,70]	-3	hSpCas9	negative selection	5095526
17168901	17168923	11	-	27760321	HT29	viability after 19 days	GATCCTCTAAGTAAGCCTAAGG	PIK3C2A	ENSG00000011405	0.2608384299351447	[113,88]	[275,109,48]	2	hSpCas9	negative selection	5095527
17169072	17169094	11	+	27760321	HT29	viability after 19 days	CCATGTCAGTACTGACTACTGG	PIK3C2A	ENSG00000011405	0.3542830966240107	[198,154]	[173,382,211]	3	hSpCas9	negative selection	5095528
17169323	17169345	11	-	27760321	HT29	viability after 19 days	TTAGACCTACTATTCAGAGAGG	PIK3C2A	ENSG00000011405	-3.6137407816460065	[29,23]	[5,0,0]	-9	hSpCas9	negative selection	5095529
17135110	17135132	11	-	27760321	HT29	viability after 16 days	CTAGCAGGAGTTCAACTAGGGG	PIK3C2A	ENSG00000011405	0.4581177033561396	[230,179]	[293,404,243]	5	hSpCas9	negative selection	5178988
17145851	17145873	11	+	27760321	HT29	viability after 16 days	TAGATGATATACCTCGTCATGG	PIK3C2A	ENSG00000011405	0.21379204007046315	[64,50]	[17,52,149]	2	hSpCas9	negative selection	5178989
17168901	17168923	11	-	27760321	HT29	viability after 16 days	GATCCTCTAAGTAAGCCTAAGG	PIK3C2A	ENSG00000011405	1.4868022286859803	[113,88]	[264,154,533]	9	hSpCas9	negative selection	5178990
17169072	17169094	11	+	27760321	HT29	viability after 16 days	CCATGTCAGTACTGACTACTGG	PIK3C2A	ENSG00000011405	-0.47063017634902904	[198,154]	[126,224,72]	-5	hSpCas9	negative selection	5178991
17169323	17169345	11	-	27760321	HT29	viability after 16 days	TTAGACCTACTATTCAGAGAGG	PIK3C2A	ENSG00000011405	-2.7508565627140182	[29,23]	[8,0,3]	-9	hSpCas9	negative selection	5178992
17135110	17135132	11	-	27760321	HT29	viability after 13 days	CTAGCAGGAGTTCAACTAGGGG	PIK3C2A	ENSG00000011405	0.3303996140596896	[230,179]	[239,354,303]	4	hSpCas9	negative selection	5262451
17145851	17145873	11	+	27760321	HT29	viability after 13 days	TAGATGATATACCTCGTCATGG	PIK3C2A	ENSG00000011405	0.5335435976737855	[64,50]	[136,122,35]	7	hSpCas9	negative selection	5262452
17168901	17168923	11	-	27760321	HT29	viability after 13 days	GATCCTCTAAGTAAGCCTAAGG	PIK3C2A	ENSG00000011405	-0.07302939471230196	[113,88]	[102,157,76]	-1	hSpCas9	negative selection	5262453
17169072	17169094	11	+	27760321	HT29	viability after 13 days	CCATGTCAGTACTGACTACTGG	PIK3C2A	ENSG00000011405	0.5615650891901149	[198,154]	[164,452,291]	7	hSpCas9	negative selection	5262454
17169323	17169345	11	-	27760321	HT29	viability after 13 days	TTAGACCTACTATTCAGAGAGG	PIK3C2A	ENSG00000011405	-0.3326050819441635	[29,23]	[15,3,52]	-4	hSpCas9	negative selection	5262455
17135110	17135132	11	-	27760321	HT29	viability after 10 days	CTAGCAGGAGTTCAACTAGGGG	PIK3C2A	ENSG00000011405	0.5256370479716308	[230,179]	[440,358,308]	7	hSpCas9	negative selection	5345914
17145851	17145873	11	+	27760321	HT29	viability after 10 days	TAGATGATATACCTCGTCATGG	PIK3C2A	ENSG00000011405	-0.2173783044429074	[64,50]	[1,70,112]	-3	hSpCas9	negative selection	5345915
17168901	17168923	11	-	27760321	HT29	viability after 10 days	GATCCTCTAAGTAAGCCTAAGG	PIK3C2A	ENSG00000011405	0.15524487531700615	[113,88]	[216,139,67]	2	hSpCas9	negative selection	5345916
17169072	17169094	11	+	27760321	HT29	viability after 10 days	CCATGTCAGTACTGACTACTGG	PIK3C2A	ENSG00000011405	-0.0788728666471814	[198,154]	[124,274,228]	-1	hSpCas9	negative selection	5345917
17169323	17169345	11	-	27760321	HT29	viability after 10 days	TTAGACCTACTATTCAGAGAGG	PIK3C2A	ENSG00000011405	0.7679114842040353	[29,23]	[68,22,78]	9	hSpCas9	negative selection	5345918
17135110	17135132	11	-	27760321	MOLM13	viability	CTAGCAGGAGTTCAACTAGGGG	PIK3C2A	ENSG00000011405	-0.16942478975383612	[340,230]	[118,160]	-1	hSpCas9	negative selection	5429377
17145851	17145873	11	+	27760321	MOLM13	viability	TAGATGATATACCTCGTCATGG	PIK3C2A	ENSG00000011405	-4.261925705014068	[76,64]	[0,2]	-9	hSpCas9	negative selection	5429378
17168901	17168923	11	-	27760321	MOLM13	viability	GATCCTCTAAGTAAGCCTAAGG	PIK3C2A	ENSG00000011405	0.8096943476210403	[136,113]	[34,198]	5	hSpCas9	negative selection	5429379
17169072	17169094	11	+	27760321	MOLM13	viability	CCATGTCAGTACTGACTACTGG	PIK3C2A	ENSG00000011405	-3.6355642254813714	[262,198]	[4,14]	-9	hSpCas9	negative selection	5429380
17169323	17169345	11	-	27760321	MOLM13	viability	TTAGACCTACTATTCAGAGAGG	PIK3C2A	ENSG00000011405	0.616874319316052	[38,29]	[0,53]	4	hSpCas9	negative selection	5429381
17169275	17169298	11	+	27661255	K562	viability	GAAGGTAAAGCATAAGTGGAAGG	PIK3C2A	ENSG00000011405	-0.17675466546268614	[438,583]	[384,337]	-5	dCas9-KRAB	negative selection	5501905
17169359	17169382	11	+	27661255	K562	viability	GAAAAGGAAGGGCTCAGAATAGG	PIK3C2A	ENSG00000011405	0.0559746642450612	[875,1138]	[890,782]	2	dCas9-KRAB	negative selection	5501906
17169368	17169391	11	+	27661255	K562	viability	GGGCTCAGAATAGGAGTAACTGG	PIK3C2A	ENSG00000011405	0.04954281656185722	[1008,950]	[884,747]	1	dCas9-KRAB	negative selection	5501907
17169716	17169739	11	-	27661255	K562	viability	GCTCAGATATCTAGCAACAGCGG	PIK3C2A	ENSG00000011405	0.17230974037458385	[602,855]	[624,675]	6	dCas9-KRAB	negative selection	5501908
17150497	17150520	11	+	27260156	BXPC3	viability	CCATCACACGTAAAAGTAACTGG	PIK3C2A	ENSG00000011405	-0.025110273284015716	[262]	[184,294,272,342]	0	hSpCas9	negative selection	5562730
17150611	17150634	11	-	27260156	BXPC3	viability	ACCAATCACCGCACAAACCCAGG	PIK3C2A	ENSG00000011405	-0.01359563891579918	[1352]	[1295,1355,1341,1644]	0	hSpCas9	negative selection	5562731
17145673	17145696	11	+	27260156	BXPC3	viability	TTTGAAGAGCCAGTTCTACTTGG	PIK3C2A	ENSG00000011405	0.31594248959162297	[1841]	[2192,2303,2409,2735]	7	hSpCas9	negative selection	5562732
17145682	17145705	11	-	27260156	BXPC3	viability	TTATCACAACCAAGTAGAACTGG	PIK3C2A	ENSG00000011405	-0.40402309453891283	[865]	[573,643,787,750]	-7	hSpCas9	negative selection	5626982
17112618	17112641	11	-	27260156	BXPC3	viability	TGTCCCCCTAAAAGTCACAATGG	PIK3C2A	ENSG00000011405	-0.015756345060082555	[353]	[297,379,297,508]	0	hSpCas9	negative selection	5626983
17112637	17112660	11	+	27260156	BXPC3	viability	GACAGCATTAGAACTGAAGAAGG	PIK3C2A	ENSG00000011405	0.01302652787432601	[89]	[94,102,72,108]	0	hSpCas9	negative selection	5626984
17150497	17150520	11	+	27260156	A673	viability	CCATCACACGTAAAAGTAACTGG	PIK3C2A	ENSG00000011405	-0.16889015384588002	[262]	[401,269,260,199]	-4	hSpCas9	negative selection	5683981
17150611	17150634	11	-	27260156	A673	viability	ACCAATCACCGCACAAACCCAGG	PIK3C2A	ENSG00000011405	-0.1455695248825153	[1352]	[1703,1351,1315,1534]	-4	hSpCas9	negative selection	5683982
17145673	17145696	11	+	27260156	A673	viability	TTTGAAGAGCCAGTTCTACTTGG	PIK3C2A	ENSG00000011405	0.2331499539421733	[1841]	[2937,2521,2560,2402]	5	hSpCas9	negative selection	5683983
17145682	17145705	11	-	27260156	A673	viability	TTATCACAACCAAGTAGAACTGG	PIK3C2A	ENSG00000011405	-0.277190564045225	[865]	[874,826,933,792]	-6	hSpCas9	negative selection	5748233
17112618	17112641	11	-	27260156	A673	viability	TGTCCCCCTAAAAGTCACAATGG	PIK3C2A	ENSG00000011405	0.09715711797241466	[353]	[457,388,448,527]	2	hSpCas9	negative selection	5748234
17112637	17112660	11	+	27260156	A673	viability	GACAGCATTAGAACTGAAGAAGG	PIK3C2A	ENSG00000011405	0.19023312661429514	[89]	[146,90,111,147]	4	hSpCas9	negative selection	5748235
17150497	17150520	11	+	27260156	A375	viability	CCATCACACGTAAAAGTAACTGG	PIK3C2A	ENSG00000011405	0.2586510898159986	[262]	[295,422,409,348]	4	hSpCas9	negative selection	5805232
17150611	17150634	11	-	27260156	A375	viability	ACCAATCACCGCACAAACCCAGG	PIK3C2A	ENSG00000011405	-0.12743477307233086	[1352]	[1583,1848,1031,1380]	-2	hSpCas9	negative selection	5805233
17145673	17145696	11	+	27260156	A375	viability	TTTGAAGAGCCAGTTCTACTTGG	PIK3C2A	ENSG00000011405	0.5592199333813013	[1841]	[3166,4059,3136,2507]	7	hSpCas9	negative selection	5805234
17145682	17145705	11	-	27260156	A375	viability	TTATCACAACCAAGTAGAACTGG	PIK3C2A	ENSG00000011405	-0.15411502418145218	[865]	[1037,985,737,884]	-2	hSpCas9	negative selection	5869484
17112618	17112641	11	-	27260156	A375	viability	TGTCCCCCTAAAAGTCACAATGG	PIK3C2A	ENSG00000011405	0.27901137497107936	[353]	[337,568,576,525]	4	hSpCas9	negative selection	5869485
17112637	17112660	11	+	27260156	A375	viability	GACAGCATTAGAACTGAAGAAGG	PIK3C2A	ENSG00000011405	0.4528587178219685	[89]	[52,195,81,238]	6	hSpCas9	negative selection	5869486
17150497	17150520	11	+	27260156	COLO741	viability	CCATCACACGTAAAAGTAACTGG	PIK3C2A	ENSG00000011405	-0.23641149295331343	[262]	[362,191,304]	-5	hSpCas9	negative selection	5926483
17150611	17150634	11	-	27260156	COLO741	viability	ACCAATCACCGCACAAACCCAGG	PIK3C2A	ENSG00000011405	-0.2349714662873208	[1352]	[1412,1630,1362]	-5	hSpCas9	negative selection	5926484
17145673	17145696	11	+	27260156	COLO741	viability	TTTGAAGAGCCAGTTCTACTTGG	PIK3C2A	ENSG00000011405	0.367589501452513	[1841]	[2921,3130,3039]	7	hSpCas9	negative selection	5926485
17145682	17145705	11	-	27260156	COLO741	viability	TTATCACAACCAAGTAGAACTGG	PIK3C2A	ENSG00000011405	-0.15729668434680588	[865]	[848,1127,985]	-3	hSpCas9	negative selection	5990735
17112618	17112641	11	-	27260156	COLO741	viability	TGTCCCCCTAAAAGTCACAATGG	PIK3C2A	ENSG00000011405	0.26287802760086854	[353]	[530,552,541]	5	hSpCas9	negative selection	5990736
17112637	17112660	11	+	27260156	COLO741	viability	GACAGCATTAGAACTGAAGAAGG	PIK3C2A	ENSG00000011405	0.5097254486961222	[89]	[182,153,155]	8	hSpCas9	negative selection	5990737
17150497	17150520	11	+	27260156	CAL120	viability	CCATCACACGTAAAAGTAACTGG	PIK3C2A	ENSG00000011405	0.1665118519345259	[262]	[406,346,353]	2	hSpCas9	negative selection	6047734
17150611	17150634	11	-	27260156	CAL120	viability	ACCAATCACCGCACAAACCCAGG	PIK3C2A	ENSG00000011405	0.2812955326561086	[1352]	[2674,1726,1833]	4	hSpCas9	negative selection	6047735
17145673	17145696	11	+	27260156	CAL120	viability	TTTGAAGAGCCAGTTCTACTTGG	PIK3C2A	ENSG00000011405	0.5955165145529562	[1841]	[4966,2618,3036]	8	hSpCas9	negative selection	6047736
17145682	17145705	11	-	27260156	CAL120	viability	TTATCACAACCAAGTAGAACTGG	PIK3C2A	ENSG00000011405	0.023966133237000586	[865]	[1790,882,723]	0	hSpCas9	negative selection	6111986
17112618	17112641	11	-	27260156	CAL120	viability	TGTCCCCCTAAAAGTCACAATGG	PIK3C2A	ENSG00000011405	-0.3636248380222867	[353]	[538,255,262]	-5	hSpCas9	negative selection	6111987
17112637	17112660	11	+	27260156	CAL120	viability	GACAGCATTAGAACTGAAGAAGG	PIK3C2A	ENSG00000011405	0.5162316900800845	[89]	[213,82,190]	7	hSpCas9	negative selection	6111988
17150497	17150520	11	+	27260156	CADOES1	viability	CCATCACACGTAAAAGTAACTGG	PIK3C2A	ENSG00000011405	0.05134820560781239	[262]	[275,239,187,311]	0	hSpCas9	negative selection	6168985
17150611	17150634	11	-	27260156	CADOES1	viability	ACCAATCACCGCACAAACCCAGG	PIK3C2A	ENSG00000011405	-0.20481559852230857	[1352]	[998,1008,1300,1056]	-4	hSpCas9	negative selection	6168986
17145673	17145696	11	+	27260156	CADOES1	viability	TTTGAAGAGCCAGTTCTACTTGG	PIK3C2A	ENSG00000011405	0.4582576685623878	[1841]	[2632,1872,2807,2088]	7	hSpCas9	negative selection	6168987
17145682	17145705	11	-	27260156	CADOES1	viability	TTATCACAACCAAGTAGAACTGG	PIK3C2A	ENSG00000011405	-0.4998328945576195	[865]	[523,571,624,556]	-7	hSpCas9	negative selection	6233237
17112618	17112641	11	-	27260156	CADOES1	viability	TGTCCCCCTAAAAGTCACAATGG	PIK3C2A	ENSG00000011405	-0.03270040022797033	[353]	[293,407,230,355]	0	hSpCas9	negative selection	6233238
17112637	17112660	11	+	27260156	CADOES1	viability	GACAGCATTAGAACTGAAGAAGG	PIK3C2A	ENSG00000011405	-0.10009938500260729	[89]	[95,64,80,69]	-2	hSpCas9	negative selection	6233239
17150497	17150520	11	+	27260156	EWS502	viability	CCATCACACGTAAAAGTAACTGG	PIK3C2A	ENSG00000011405	-0.2328430686335019	[262]	[184,248,213,309]	-4	hSpCas9	negative selection	6290236
17150611	17150634	11	-	27260156	EWS502	viability	ACCAATCACCGCACAAACCCAGG	PIK3C2A	ENSG00000011405	-0.0012478669804005804	[1352]	[1456,1451,1409,1395]	0	hSpCas9	negative selection	6290237
17145673	17145696	11	+	27260156	EWS502	viability	TTTGAAGAGCCAGTTCTACTTGG	PIK3C2A	ENSG00000011405	0.5069349421415659	[1841]	[2701,2441,2945,3031]	8	hSpCas9	negative selection	6290238
17145682	17145705	11	-	27260156	EWS502	viability	TTATCACAACCAAGTAGAACTGG	PIK3C2A	ENSG00000011405	-0.06363420195933911	[865]	[631,969,827,1119]	-1	hSpCas9	negative selection	6354488
17112618	17112641	11	-	27260156	EWS502	viability	TGTCCCCCTAAAAGTCACAATGG	PIK3C2A	ENSG00000011405	0.24956493737401772	[353]	[320,486,559,426]	4	hSpCas9	negative selection	6354489
17112637	17112660	11	+	27260156	EWS502	viability	GACAGCATTAGAACTGAAGAAGG	PIK3C2A	ENSG00000011405	0.09784985100148758	[89]	[127,52,168,53]	1	hSpCas9	negative selection	6354490
17150497	17150520	11	+	27260156	EW8	viability	CCATCACACGTAAAAGTAACTGG	PIK3C2A	ENSG00000011405	-0.22187446643222852	[262]	[231,202,87,228]	-4	hSpCas9	negative selection	6411487
17150611	17150634	11	-	27260156	EW8	viability	ACCAATCACCGCACAAACCCAGG	PIK3C2A	ENSG00000011405	-0.2502682346011995	[1352]	[1189,1070,760,720]	-5	hSpCas9	negative selection	6411488
17145673	17145696	11	+	27260156	EW8	viability	TTTGAAGAGCCAGTTCTACTTGG	PIK3C2A	ENSG00000011405	0.33662511914158877	[1841]	[1965,1972,1558,2100]	6	hSpCas9	negative selection	6411489
17145682	17145705	11	-	27260156	EW8	viability	TTATCACAACCAAGTAGAACTGG	PIK3C2A	ENSG00000011405	-0.2177148676293894	[865]	[798,739,545,359]	-4	hSpCas9	negative selection	6475739
17112618	17112641	11	-	27260156	EW8	viability	TGTCCCCCTAAAAGTCACAATGG	PIK3C2A	ENSG00000011405	0.15615012078934587	[353]	[371,408,219,299]	3	hSpCas9	negative selection	6475740
17112637	17112660	11	+	27260156	EW8	viability	GACAGCATTAGAACTGAAGAAGG	PIK3C2A	ENSG00000011405	0.12501644278901836	[89]	[176,76,54,23]	2	hSpCas9	negative selection	6475741
17150497	17150520	11	+	27260156	CORL105	viability	CCATCACACGTAAAAGTAACTGG	PIK3C2A	ENSG00000011405	-0.07952124077145006	[262]	[240,340,286,292]	-1	hSpCas9	negative selection	6532738
17150611	17150634	11	-	27260156	CORL105	viability	ACCAATCACCGCACAAACCCAGG	PIK3C2A	ENSG00000011405	-0.07663573515668376	[1352]	[1391,1521,1508,1580]	-1	hSpCas9	negative selection	6532739
17145673	17145696	11	+	27260156	CORL105	viability	TTTGAAGAGCCAGTTCTACTTGG	PIK3C2A	ENSG00000011405	0.3833074289701015	[1841]	[2718,2920,3016,2619]	7	hSpCas9	negative selection	6532740
17145682	17145705	11	-	27260156	CORL105	viability	TTATCACAACCAAGTAGAACTGG	PIK3C2A	ENSG00000011405	-0.3321411602860136	[865]	[660,751,815,988]	-6	hSpCas9	negative selection	6596990
17112618	17112641	11	-	27260156	CORL105	viability	TGTCCCCCTAAAAGTCACAATGG	PIK3C2A	ENSG00000011405	-0.15276360876555267	[353]	[307,311,469,414]	-3	hSpCas9	negative selection	6596991
17112637	17112660	11	+	27260156	CORL105	viability	GACAGCATTAGAACTGAAGAAGG	PIK3C2A	ENSG00000011405	0.20028471829861738	[89]	[111,162,119,87]	4	hSpCas9	negative selection	6596992
17150497	17150520	11	+	27260156	HS294T	viability	CCATCACACGTAAAAGTAACTGG	PIK3C2A	ENSG00000011405	0.012127899578099344	[262]	[69,85,137,122]	0	hSpCas9	negative selection	6653989
17150611	17150634	11	-	27260156	HS294T	viability	ACCAATCACCGCACAAACCCAGG	PIK3C2A	ENSG00000011405	-0.07982977134167313	[1352]	[466,445,397,706]	-1	hSpCas9	negative selection	6653990
17145673	17145696	11	+	27260156	HS294T	viability	TTTGAAGAGCCAGTTCTACTTGG	PIK3C2A	ENSG00000011405	0.521899188772589	[1841]	[1248,747,951,1145]	7	hSpCas9	negative selection	6653991
17145682	17145705	11	-	27260156	HS294T	viability	TTATCACAACCAAGTAGAACTGG	PIK3C2A	ENSG00000011405	-0.14848844217642543	[865]	[356,252,284,309]	-2	hSpCas9	negative selection	6718241
17112618	17112641	11	-	27260156	HS294T	viability	TGTCCCCCTAAAAGTCACAATGG	PIK3C2A	ENSG00000011405	-0.35422543027401526	[353]	[93,112,109,112]	-5	hSpCas9	negative selection	6718242
17112637	17112660	11	+	27260156	HS294T	viability	GACAGCATTAGAACTGAAGAAGG	PIK3C2A	ENSG00000011405	0.042388390637607465	[89]	[36,34,20,52]	0	hSpCas9	negative selection	6718243
17150497	17150520	11	+	27260156	HCC44	viability	CCATCACACGTAAAAGTAACTGG	PIK3C2A	ENSG00000011405	0.2175113915267447	[262]	[412,263,413,319]	3	hSpCas9	negative selection	6775240
17150611	17150634	11	-	27260156	HCC44	viability	ACCAATCACCGCACAAACCCAGG	PIK3C2A	ENSG00000011405	-0.006706046159987711	[1352]	[1463,1340,1881,1476]	0	hSpCas9	negative selection	6775241
17145673	17145696	11	+	27260156	HCC44	viability	TTTGAAGAGCCAGTTCTACTTGG	PIK3C2A	ENSG00000011405	0.617640163625536	[1841]	[3335,2867,3767,2953]	8	hSpCas9	negative selection	6775242
17145682	17145705	11	-	27260156	HCC44	viability	TTATCACAACCAAGTAGAACTGG	PIK3C2A	ENSG00000011405	-0.16622580430188227	[865]	[930,825,890,851]	-3	hSpCas9	negative selection	6839492
17112618	17112641	11	-	27260156	HCC44	viability	TGTCCCCCTAAAAGTCACAATGG	PIK3C2A	ENSG00000011405	0.45137226298925615	[353]	[637,532,502,514]	7	hSpCas9	negative selection	6839493
17112637	17112660	11	+	27260156	HCC44	viability	GACAGCATTAGAACTGAAGAAGG	PIK3C2A	ENSG00000011405	0.043435832169138155	[89]	[104,39,191,105]	0	hSpCas9	negative selection	6839494
17150497	17150520	11	+	27260156	G402	viability	CCATCACACGTAAAAGTAACTGG	PIK3C2A	ENSG00000011405	-0.002485417257906075	[262]	[278,267,399,323]	0	hSpCas9	negative selection	6896491
17150611	17150634	11	-	27260156	G402	viability	ACCAATCACCGCACAAACCCAGG	PIK3C2A	ENSG00000011405	-0.053235247379131545	[1352]	[1841,1387,1418,1726]	0	hSpCas9	negative selection	6896492
17145673	17145696	11	+	27260156	G402	viability	TTTGAAGAGCCAGTTCTACTTGG	PIK3C2A	ENSG00000011405	0.6800727745982273	[1841]	[4527,4067,2467,3492]	8	hSpCas9	negative selection	6896493
17145682	17145705	11	-	27260156	G402	viability	TTATCACAACCAAGTAGAACTGG	PIK3C2A	ENSG00000011405	-0.591179191046362	[865]	[336,1384,321,743]	-6	hSpCas9	negative selection	6960743
17112618	17112641	11	-	27260156	G402	viability	TGTCCCCCTAAAAGTCACAATGG	PIK3C2A	ENSG00000011405	0.4191790246188208	[353]	[845,576,285,634]	5	hSpCas9	negative selection	6960744
17112637	17112660	11	+	27260156	G402	viability	GACAGCATTAGAACTGAAGAAGG	PIK3C2A	ENSG00000011405	0.9868289880745942	[89]	[118,472,265,21]	9	hSpCas9	negative selection	6960745
17150497	17150520	11	+	27260156	L33	viability	CCATCACACGTAAAAGTAACTGG	PIK3C2A	ENSG00000011405	-0.12113092974442763	[262]	[140,60,183,385]	-3	hSpCas9	negative selection	7017742
17150611	17150634	11	-	27260156	L33	viability	ACCAATCACCGCACAAACCCAGG	PIK3C2A	ENSG00000011405	-0.03812214223686894	[1352]	[1143,545,974,1248]	-1	hSpCas9	negative selection	7017743
17145673	17145696	11	+	27260156	L33	viability	TTTGAAGAGCCAGTTCTACTTGG	PIK3C2A	ENSG00000011405	0.3427719604384456	[1841]	[2068,984,1655,2244]	7	hSpCas9	negative selection	7017744
17145682	17145705	11	-	27260156	L33	viability	TTATCACAACCAAGTAGAACTGG	PIK3C2A	ENSG00000011405	-0.4780316409968481	[865]	[553,284,485,467]	-8	hSpCas9	negative selection	7081994
17112618	17112641	11	-	27260156	L33	viability	TGTCCCCCTAAAAGTCACAATGG	PIK3C2A	ENSG00000011405	-0.22018609265844563	[353]	[283,130,203,287]	-5	hSpCas9	negative selection	7081995
17112637	17112660	11	+	27260156	L33	viability	GACAGCATTAGAACTGAAGAAGG	PIK3C2A	ENSG00000011405	0.4381290025811453	[89]	[86,54,100,106]	8	hSpCas9	negative selection	7081996
17150497	17150520	11	+	27260156	K562	viability	CCATCACACGTAAAAGTAACTGG	PIK3C2A	ENSG00000011405	0.359459859579332	[262]	[176,353,308,343]	4	hSpCas9	negative selection	7138993
17150611	17150634	11	-	27260156	K562	viability	ACCAATCACCGCACAAACCCAGG	PIK3C2A	ENSG00000011405	-0.11963036459529763	[1352]	[1080,1092,848,1359]	-1	hSpCas9	negative selection	7138994
17145673	17145696	11	+	27260156	K562	viability	TTTGAAGAGCCAGTTCTACTTGG	PIK3C2A	ENSG00000011405	0.7867528384723821	[1841]	[3112,2241,2135,3669]	8	hSpCas9	negative selection	7138995
17145682	17145705	11	-	27260156	K562	viability	TTATCACAACCAAGTAGAACTGG	PIK3C2A	ENSG00000011405	-0.11677228975015008	[865]	[1048,502,700,607]	-1	hSpCas9	negative selection	7203245
17112618	17112641	11	-	27260156	K562	viability	TGTCCCCCTAAAAGTCACAATGG	PIK3C2A	ENSG00000011405	-0.1744636877638313	[353]	[332,129,367,277]	-2	hSpCas9	negative selection	7203246
17112637	17112660	11	+	27260156	K562	viability	GACAGCATTAGAACTGAAGAAGG	PIK3C2A	ENSG00000011405	-0.15757889492513089	[89]	[29,204,32,26]	-2	hSpCas9	negative selection	7203247
17150497	17150520	11	+	27260156	HT29	viability	CCATCACACGTAAAAGTAACTGG	PIK3C2A	ENSG00000011405	-0.41790451822320507	[262]	[256,231,261,208]	-6	hSpCas9	negative selection	7260244
17150611	17150634	11	-	27260156	HT29	viability	ACCAATCACCGCACAAACCCAGG	PIK3C2A	ENSG00000011405	-0.14259076900703893	[1352]	[1570,1476,1756,1186]	-3	hSpCas9	negative selection	7260245
17145673	17145696	11	+	27260156	HT29	viability	TTTGAAGAGCCAGTTCTACTTGG	PIK3C2A	ENSG00000011405	0.35588384337163026	[1841]	[2980,3252,2369,2877]	7	hSpCas9	negative selection	7260246
17145682	17145705	11	-	27260156	HT29	viability	TTATCACAACCAAGTAGAACTGG	PIK3C2A	ENSG00000011405	-0.21287081812285102	[865]	[1081,826,1120,636]	-4	hSpCas9	negative selection	7324496
17112618	17112641	11	-	27260156	HT29	viability	TGTCCCCCTAAAAGTCACAATGG	PIK3C2A	ENSG00000011405	-0.05283154889913433	[353]	[330,377,497,436]	-1	hSpCas9	negative selection	7324497
17112637	17112660	11	+	27260156	HT29	viability	GACAGCATTAGAACTGAAGAAGG	PIK3C2A	ENSG00000011405	0.20611328393550643	[89]	[170,112,120,103]	4	hSpCas9	negative selection	7324498
17150497	17150520	11	+	27260156	MHHES1	viability	CCATCACACGTAAAAGTAACTGG	PIK3C2A	ENSG00000011405	-0.15656438805446693	[262]	[350,260,278,192]	-3	hSpCas9	negative selection	7381495
17150611	17150634	11	-	27260156	MHHES1	viability	ACCAATCACCGCACAAACCCAGG	PIK3C2A	ENSG00000011405	-0.42726949619937993	[1352]	[1328,1284,1239,776]	-7	hSpCas9	negative selection	7381496
17145673	17145696	11	+	27260156	MHHES1	viability	TTTGAAGAGCCAGTTCTACTTGG	PIK3C2A	ENSG00000011405	0.19762423674597152	[1841]	[2612,2652,2244,2076]	3	hSpCas9	negative selection	7381497
17145682	17145705	11	-	27260156	MHHES1	viability	TTATCACAACCAAGTAGAACTGG	PIK3C2A	ENSG00000011405	-0.10362368310701564	[865]	[939,1157,670,875]	-2	hSpCas9	negative selection	7445747
17112618	17112641	11	-	27260156	MHHES1	viability	TGTCCCCCTAAAAGTCACAATGG	PIK3C2A	ENSG00000011405	0.5226593909731653	[353]	[337,1138,534,347]	8	hSpCas9	negative selection	7445748
17112637	17112660	11	+	27260156	MHHES1	viability	GACAGCATTAGAACTGAAGAAGG	PIK3C2A	ENSG00000011405	0.45770231626596836	[89]	[191,149,151,80]	7	hSpCas9	negative selection	7445749
17150497	17150520	11	+	27260156	MEWO	viability	CCATCACACGTAAAAGTAACTGG	PIK3C2A	ENSG00000011405	-0.1800390052909402	[262]	[255,222,179]	-4	hSpCas9	negative selection	7502746
17150611	17150634	11	-	27260156	MEWO	viability	ACCAATCACCGCACAAACCCAGG	PIK3C2A	ENSG00000011405	-0.07545612932744339	[1352]	[1284,1176,1157]	-2	hSpCas9	negative selection	7502747
17145673	17145696	11	+	27260156	MEWO	viability	TTTGAAGAGCCAGTTCTACTTGG	PIK3C2A	ENSG00000011405	0.09807948133584787	[1841]	[2186,1750,1661]	2	hSpCas9	negative selection	7502748
17145682	17145705	11	-	27260156	MEWO	viability	TTATCACAACCAAGTAGAACTGG	PIK3C2A	ENSG00000011405	-0.14391739158855343	[865]	[919,699,615]	-3	hSpCas9	negative selection	7566998
17112618	17112641	11	-	27260156	MEWO	viability	TGTCCCCCTAAAAGTCACAATGG	PIK3C2A	ENSG00000011405	-0.07555097382573234	[353]	[421,246,294]	-2	hSpCas9	negative selection	7566999
17112637	17112660	11	+	27260156	MEWO	viability	GACAGCATTAGAACTGAAGAAGG	PIK3C2A	ENSG00000011405	0.5125334925264817	[89]	[199,78,96]	9	hSpCas9	negative selection	7567000
17150497	17150520	11	+	27260156	LNCAPCLONEFGC	viability	CCATCACACGTAAAAGTAACTGG	PIK3C2A	ENSG00000011405	0.2475445802274776	[262]	[256,178,339,370]	4	hSpCas9	negative selection	7623997
17150611	17150634	11	-	27260156	LNCAPCLONEFGC	viability	ACCAATCACCGCACAAACCCAGG	PIK3C2A	ENSG00000011405	0.012613339707477689	[1352]	[1464,1040,1396,1073]	0	hSpCas9	negative selection	7623998
17145673	17145696	11	+	27260156	LNCAPCLONEFGC	viability	TTTGAAGAGCCAGTTCTACTTGG	PIK3C2A	ENSG00000011405	0.44863604057458684	[1841]	[2316,1882,2596,2382]	7	hSpCas9	negative selection	7623999
17145682	17145705	11	-	27260156	LNCAPCLONEFGC	viability	TTATCACAACCAAGTAGAACTGG	PIK3C2A	ENSG00000011405	-0.3969141214809802	[865]	[527,444,891,572]	-6	hSpCas9	negative selection	7688249
17112618	17112641	11	-	27260156	LNCAPCLONEFGC	viability	TGTCCCCCTAAAAGTCACAATGG	PIK3C2A	ENSG00000011405	-0.014605892406991616	[353]	[263,329,345,333]	0	hSpCas9	negative selection	7688250
17112637	17112660	11	+	27260156	LNCAPCLONEFGC	viability	GACAGCATTAGAACTGAAGAAGG	PIK3C2A	ENSG00000011405	0.19978006450797015	[89]	[55,94,139,90]	3	hSpCas9	negative selection	7688251
17150497	17150520	11	+	27260156	PANC0327	viability	CCATCACACGTAAAAGTAACTGG	PIK3C2A	ENSG00000011405	0.3885640108608969	[262]	[344,303,422,154]	6	hSpCas9	negative selection	7745248
17150611	17150634	11	-	27260156	PANC0327	viability	ACCAATCACCGCACAAACCCAGG	PIK3C2A	ENSG00000011405	0.051081188995635296	[1352]	[1374,766,1451,1458]	0	hSpCas9	negative selection	7745249
17145673	17145696	11	+	27260156	PANC0327	viability	TTTGAAGAGCCAGTTCTACTTGG	PIK3C2A	ENSG00000011405	0.4084041544301451	[1841]	[2432,2266,2000,1993]	6	hSpCas9	negative selection	7745250
17145682	17145705	11	-	27260156	PANC0327	viability	TTATCACAACCAAGTAGAACTGG	PIK3C2A	ENSG00000011405	-0.1947749378682322	[865]	[895,629,592,592]	-3	hSpCas9	negative selection	7809500
17112618	17112641	11	-	27260156	PANC0327	viability	TGTCCCCCTAAAAGTCACAATGG	PIK3C2A	ENSG00000011405	0.3369463687439038	[353]	[521,387,342,346]	5	hSpCas9	negative selection	7809501
17112637	17112660	11	+	27260156	PANC0327	viability	GACAGCATTAGAACTGAAGAAGG	PIK3C2A	ENSG00000011405	0.07532511698082978	[89]	[96,68,119,53]	1	hSpCas9	negative selection	7809502
17150497	17150520	11	+	27260156	NCIH2009	viability	CCATCACACGTAAAAGTAACTGG	PIK3C2A	ENSG00000011405	0.09176540694876179	[262]	[552,280,373]	1	hSpCas9	negative selection	7866499
17150611	17150634	11	-	27260156	NCIH2009	viability	ACCAATCACCGCACAAACCCAGG	PIK3C2A	ENSG00000011405	0.2757496210098975	[1352]	[2457,1854,2589]	4	hSpCas9	negative selection	7866500
17145673	17145696	11	+	27260156	NCIH2009	viability	TTTGAAGAGCCAGTTCTACTTGG	PIK3C2A	ENSG00000011405	0.3732042258048409	[1841]	[3675,3173,3214]	5	hSpCas9	negative selection	7866501
17145682	17145705	11	-	27260156	NCIH2009	viability	TTATCACAACCAAGTAGAACTGG	PIK3C2A	ENSG00000011405	-0.5945962951657862	[865]	[930,638,860]	-6	hSpCas9	negative selection	7930751
17112618	17112641	11	-	27260156	NCIH2009	viability	TGTCCCCCTAAAAGTCACAATGG	PIK3C2A	ENSG00000011405	0.7132730328892531	[353]	[706,522,1185]	8	hSpCas9	negative selection	7930752
17112637	17112660	11	+	27260156	NCIH2009	viability	GACAGCATTAGAACTGAAGAAGG	PIK3C2A	ENSG00000011405	0.11505677961817451	[89]	[125,152,126]	1	hSpCas9	negative selection	7930753
17150497	17150520	11	+	27260156	NCIH1373	viability	CCATCACACGTAAAAGTAACTGG	PIK3C2A	ENSG00000011405	0.6107587015561851	[262]	[208,695,338,129]	6	hSpCas9	negative selection	7987750
17150611	17150634	11	-	27260156	NCIH1373	viability	ACCAATCACCGCACAAACCCAGG	PIK3C2A	ENSG00000011405	0.2793715274428328	[1352]	[2171,1576,1575,559]	2	hSpCas9	negative selection	7987751
17145673	17145696	11	+	27260156	NCIH1373	viability	TTTGAAGAGCCAGTTCTACTTGG	PIK3C2A	ENSG00000011405	0.9531397447078902	[1841]	[4506,2872,3611,1382]	8	hSpCas9	negative selection	7987752
17145682	17145705	11	-	27260156	NCIH1373	viability	TTATCACAACCAAGTAGAACTGG	PIK3C2A	ENSG00000011405	-0.3066931778483216	[865]	[843,740,821,193]	-3	hSpCas9	negative selection	8052002
17112618	17112641	11	-	27260156	NCIH1373	viability	TGTCCCCCTAAAAGTCACAATGG	PIK3C2A	ENSG00000011405	-0.9744369774805339	[353]	[294,162,162,53]	-7	hSpCas9	negative selection	8052003
17112637	17112660	11	+	27260156	NCIH1373	viability	GACAGCATTAGAACTGAAGAAGG	PIK3C2A	ENSG00000011405	-0.9691718796371775	[89]	[24,98,26,11]	-7	hSpCas9	negative selection	8052004
17150497	17150520	11	+	27260156	PATU8902	viability	CCATCACACGTAAAAGTAACTGG	PIK3C2A	ENSG00000011405	0.45150922366573315	[262]	[835,373,201,681]	5	hSpCas9	negative selection	8109001
17150611	17150634	11	-	27260156	PATU8902	viability	ACCAATCACCGCACAAACCCAGG	PIK3C2A	ENSG00000011405	-0.20701209045414926	[1352]	[1609,1913,1251,1868]	-2	hSpCas9	negative selection	8109002
17145673	17145696	11	+	27260156	PATU8902	viability	TTTGAAGAGCCAGTTCTACTTGG	PIK3C2A	ENSG00000011405	0.7305998003836991	[1841]	[4884,4399,3287,4718]	7	hSpCas9	negative selection	8109003
17145682	17145705	11	-	27260156	PATU8902	viability	TTATCACAACCAAGTAGAACTGG	PIK3C2A	ENSG00000011405	-0.05937656318746942	[865]	[1376,885,892,1579]	0	hSpCas9	negative selection	8173253
17112618	17112641	11	-	27260156	PATU8902	viability	TGTCCCCCTAAAAGTCACAATGG	PIK3C2A	ENSG00000011405	-0.3456746456080844	[353]	[515,392,244,435]	-3	hSpCas9	negative selection	8173254
17112637	17112660	11	+	27260156	PATU8902	viability	GACAGCATTAGAACTGAAGAAGG	PIK3C2A	ENSG00000011405	0.009194656980371363	[89]	[37,100,116,267]	0	hSpCas9	negative selection	8173255
17150497	17150520	11	+	27260156	PANC1	viability	CCATCACACGTAAAAGTAACTGG	PIK3C2A	ENSG00000011405	0.6036191200654986	[262]	[243,547,348,280]	8	hSpCas9	negative selection	8230252
17150611	17150634	11	-	27260156	PANC1	viability	ACCAATCACCGCACAAACCCAGG	PIK3C2A	ENSG00000011405	0.12145481925300405	[1352]	[1300,1509,1470,870]	2	hSpCas9	negative selection	8230253
17145673	17145696	11	+	27260156	PANC1	viability	TTTGAAGAGCCAGTTCTACTTGG	PIK3C2A	ENSG00000011405	0.5560643976466517	[1841]	[2495,2714,2401,1814]	8	hSpCas9	negative selection	8230254
17145682	17145705	11	-	27260156	PANC1	viability	TTATCACAACCAAGTAGAACTGG	PIK3C2A	ENSG00000011405	0.1649075107519623	[865]	[700,938,843,857]	2	hSpCas9	negative selection	8294504
17112618	17112641	11	-	27260156	PANC1	viability	TGTCCCCCTAAAAGTCACAATGG	PIK3C2A	ENSG00000011405	0.3224830307102806	[353]	[349,236,348,524]	5	hSpCas9	negative selection	8294505
17112637	17112660	11	+	27260156	PANC1	viability	GACAGCATTAGAACTGAAGAAGG	PIK3C2A	ENSG00000011405	0.39808126695860424	[89]	[144,106,61,92]	6	hSpCas9	negative selection	8294506
17150497	17150520	11	+	27260156	PANC0813	viability	CCATCACACGTAAAAGTAACTGG	PIK3C2A	ENSG00000011405	0.15548649072516674	[262]	[379,352,320,325]	2	hSpCas9	negative selection	8351503
17150611	17150634	11	-	27260156	PANC0813	viability	ACCAATCACCGCACAAACCCAGG	PIK3C2A	ENSG00000011405	-0.09394294768292566	[1352]	[1522,1564,1439,1431]	-1	hSpCas9	negative selection	8351504
17145673	17145696	11	+	27260156	PANC0813	viability	TTTGAAGAGCCAGTTCTACTTGG	PIK3C2A	ENSG00000011405	0.48971788128831983	[1841]	[3794,2964,2884,2596]	7	hSpCas9	negative selection	8351505
17145682	17145705	11	-	27260156	PANC0813	viability	TTATCACAACCAAGTAGAACTGG	PIK3C2A	ENSG00000011405	-0.014334920074212443	[865]	[1386,624,981,1064]	0	hSpCas9	negative selection	8415755
17112618	17112641	11	-	27260156	PANC0813	viability	TGTCCCCCTAAAAGTCACAATGG	PIK3C2A	ENSG00000011405	0.4596465237728141	[353]	[783,429,487,601]	7	hSpCas9	negative selection	8415756
17112637	17112660	11	+	27260156	PANC0813	viability	GACAGCATTAGAACTGAAGAAGG	PIK3C2A	ENSG00000011405	0.29585956389082124	[89]	[106,219,86,103]	5	hSpCas9	negative selection	8415757
17150497	17150520	11	+	27260156	RDES	viability	CCATCACACGTAAAAGTAACTGG	PIK3C2A	ENSG00000011405	0.1360435410628431	[262]	[236,295,338,497]	2	hSpCas9	negative selection	8472754
17150611	17150634	11	-	27260156	RDES	viability	ACCAATCACCGCACAAACCCAGG	PIK3C2A	ENSG00000011405	0.009003534515586775	[1352]	[1261,1457,1897,1707]	0	hSpCas9	negative selection	8472755
17145673	17145696	11	+	27260156	RDES	viability	TTTGAAGAGCCAGTTCTACTTGG	PIK3C2A	ENSG00000011405	0.5563487659889317	[1841]	[2667,3146,3047,3674]	8	hSpCas9	negative selection	8472756
17145682	17145705	11	-	27260156	RDES	viability	TTATCACAACCAAGTAGAACTGG	PIK3C2A	ENSG00000011405	0.017900422129963567	[865]	[849,792,1032,1450]	0	hSpCas9	negative selection	8537006
17112618	17112641	11	-	27260156	RDES	viability	TGTCCCCCTAAAAGTCACAATGG	PIK3C2A	ENSG00000011405	0.23121692033747032	[353]	[309,455,602,589]	4	hSpCas9	negative selection	8537007
17112637	17112660	11	+	27260156	RDES	viability	GACAGCATTAGAACTGAAGAAGG	PIK3C2A	ENSG00000011405	0.6410453750579537	[89]	[164,116,144,225]	8	hSpCas9	negative selection	8537008
17150497	17150520	11	+	27260156	PC3	viability	CCATCACACGTAAAAGTAACTGG	PIK3C2A	ENSG00000011405	-0.11534036030617245	[262]	[93,318,518,185]	-3	hSpCas9	negative selection	8594005
17150611	17150634	11	-	27260156	PC3	viability	ACCAATCACCGCACAAACCCAGG	PIK3C2A	ENSG00000011405	-0.15911690834596293	[1352]	[771,1098,1971,1370]	-4	hSpCas9	negative selection	8594006
17145673	17145696	11	+	27260156	PC3	viability	TTTGAAGAGCCAGTTCTACTTGG	PIK3C2A	ENSG00000011405	0.20693140120030584	[1841]	[1410,2091,3126,2341]	4	hSpCas9	negative selection	8594007
17145682	17145705	11	-	27260156	PC3	viability	TTATCACAACCAAGTAGAACTGG	PIK3C2A	ENSG00000011405	-0.3382473689606247	[865]	[483,732,732,814]	-6	hSpCas9	negative selection	8658257
17112618	17112641	11	-	27260156	PC3	viability	TGTCCCCCTAAAAGTCACAATGG	PIK3C2A	ENSG00000011405	-0.34552147079173606	[353]	[133,201,425,460]	-7	hSpCas9	negative selection	8658258
17112637	17112660	11	+	27260156	PC3	viability	GACAGCATTAGAACTGAAGAAGG	PIK3C2A	ENSG00000011405	0.1043961623146914	[89]	[38,144,210,48]	2	hSpCas9	negative selection	8658259
17150497	17150520	11	+	27260156	PATU8988T	viability	CCATCACACGTAAAAGTAACTGG	PIK3C2A	ENSG00000011405	-0.03500363728473177	[262]	[331,279,240,132]	0	hSpCas9	negative selection	8715256
17150611	17150634	11	-	27260156	PATU8988T	viability	ACCAATCACCGCACAAACCCAGG	PIK3C2A	ENSG00000011405	0.22657147409787504	[1352]	[1426,1691,1401,1621]	4	hSpCas9	negative selection	8715257
17145673	17145696	11	+	27260156	PATU8988T	viability	TTTGAAGAGCCAGTTCTACTTGG	PIK3C2A	ENSG00000011405	0.29159268189658993	[1841]	[1948,2423,1988,2394]	5	hSpCas9	negative selection	8715258
17145682	17145705	11	-	27260156	PATU8988T	viability	TTATCACAACCAAGTAGAACTGG	PIK3C2A	ENSG00000011405	-0.15280363615686854	[865]	[559,969,729,772]	-3	hSpCas9	negative selection	8779508
17112618	17112641	11	-	27260156	PATU8988T	viability	TGTCCCCCTAAAAGTCACAATGG	PIK3C2A	ENSG00000011405	0.06500715006498625	[353]	[362,387,291,394]	1	hSpCas9	negative selection	8779509
17112637	17112660	11	+	27260156	PATU8988T	viability	GACAGCATTAGAACTGAAGAAGG	PIK3C2A	ENSG00000011405	0.37786491546634604	[89]	[71,79,240,48]	6	hSpCas9	negative selection	8779510
17150497	17150520	11	+	27260156	T47D	viability	CCATCACACGTAAAAGTAACTGG	PIK3C2A	ENSG00000011405	-0.06015184962604003	[262]	[401,198,313,267]	-1	hSpCas9	negative selection	8836507
17150611	17150634	11	-	27260156	T47D	viability	ACCAATCACCGCACAAACCCAGG	PIK3C2A	ENSG00000011405	-0.03339995083093372	[1352]	[1585,1284,1603,1711]	0	hSpCas9	negative selection	8836508
17145673	17145696	11	+	27260156	T47D	viability	TTTGAAGAGCCAGTTCTACTTGG	PIK3C2A	ENSG00000011405	0.3803523826862274	[1841]	[2737,2614,2903,2932]	7	hSpCas9	negative selection	8836509
17145682	17145705	11	-	27260156	T47D	viability	TTATCACAACCAAGTAGAACTGG	PIK3C2A	ENSG00000011405	-0.1432642252391364	[865]	[1039,788,880,956]	-3	hSpCas9	negative selection	8900759
17112618	17112641	11	-	27260156	T47D	viability	TGTCCCCCTAAAAGTCACAATGG	PIK3C2A	ENSG00000011405	0.08636224115482766	[353]	[444,374,371,569]	1	hSpCas9	negative selection	8900760
17112637	17112660	11	+	27260156	T47D	viability	GACAGCATTAGAACTGAAGAAGG	PIK3C2A	ENSG00000011405	0.6504899305872687	[89]	[124,152,160,221]	9	hSpCas9	negative selection	8900761
17150497	17150520	11	+	27260156	SU8686	viability	CCATCACACGTAAAAGTAACTGG	PIK3C2A	ENSG00000011405	-0.11805895058285465	[262]	[233,185,214,348]	-2	hSpCas9	negative selection	8957758
17150611	17150634	11	-	27260156	SU8686	viability	ACCAATCACCGCACAAACCCAGG	PIK3C2A	ENSG00000011405	0.09451129793075497	[1352]	[1286,1366,1586,1520]	1	hSpCas9	negative selection	8957759
17145673	17145696	11	+	27260156	SU8686	viability	TTTGAAGAGCCAGTTCTACTTGG	PIK3C2A	ENSG00000011405	0.5619625463074671	[1841]	[2328,2183,3164,3306]	8	hSpCas9	negative selection	8957760
17145682	17145705	11	-	27260156	SU8686	viability	TTATCACAACCAAGTAGAACTGG	PIK3C2A	ENSG00000011405	-0.25384577663403196	[865]	[717,660,589,946]	-4	hSpCas9	negative selection	9022010
17112618	17112641	11	-	27260156	SU8686	viability	TGTCCCCCTAAAAGTCACAATGG	PIK3C2A	ENSG00000011405	0.2896988705340411	[353]	[397,379,463,491]	5	hSpCas9	negative selection	9022011
17112637	17112660	11	+	27260156	SU8686	viability	GACAGCATTAGAACTGAAGAAGG	PIK3C2A	ENSG00000011405	-0.09176210457558964	[89]	[98,28,72,148]	-2	hSpCas9	negative selection	9022012
17150497	17150520	11	+	27260156	SKES1	viability	CCATCACACGTAAAAGTAACTGG	PIK3C2A	ENSG00000011405	0.027492123260832946	[262]	[293,234,212,318]	0	hSpCas9	negative selection	9079009
17150611	17150634	11	-	27260156	SKES1	viability	ACCAATCACCGCACAAACCCAGG	PIK3C2A	ENSG00000011405	-0.11149343980546367	[1352]	[1401,1153,1195,1242]	-2	hSpCas9	negative selection	9079010
17145673	17145696	11	+	27260156	SKES1	viability	TTTGAAGAGCCAGTTCTACTTGG	PIK3C2A	ENSG00000011405	0.24529218193007507	[1841]	[2207,2776,1966,1854]	5	hSpCas9	negative selection	9079011
17145682	17145705	11	-	27260156	SKES1	viability	TTATCACAACCAAGTAGAACTGG	PIK3C2A	ENSG00000011405	-0.2693859663621746	[865]	[854,838,721,502]	-5	hSpCas9	negative selection	9143261
17112618	17112641	11	-	27260156	SKES1	viability	TGTCCCCCTAAAAGTCACAATGG	PIK3C2A	ENSG00000011405	-0.2475826310576394	[353]	[378,282,320,221]	-5	hSpCas9	negative selection	9143262
17112637	17112660	11	+	27260156	SKES1	viability	GACAGCATTAGAACTGAAGAAGG	PIK3C2A	ENSG00000011405	-0.37859959567284296	[89]	[61,105,38,71]	-7	hSpCas9	negative selection	9143263
17150497	17150520	11	+	27260156	TOV112D	viability	CCATCACACGTAAAAGTAACTGG	PIK3C2A	ENSG00000011405	-0.7541208210493573	[262]	[179,143,162,136]	-9	hSpCas9	negative selection	9200260
17150611	17150634	11	-	27260156	TOV112D	viability	ACCAATCACCGCACAAACCCAGG	PIK3C2A	ENSG00000011405	-0.24171129709191863	[1352]	[1553,1257,1075,766]	-5	hSpCas9	negative selection	9200261
17145673	17145696	11	+	27260156	TOV112D	viability	TTTGAAGAGCCAGTTCTACTTGG	PIK3C2A	ENSG00000011405	0.3824132802638571	[1841]	[2333,2702,2216,2427]	7	hSpCas9	negative selection	9200262
17145682	17145705	11	-	27260156	TOV112D	viability	TTATCACAACCAAGTAGAACTGG	PIK3C2A	ENSG00000011405	-0.36776226904525755	[865]	[649,622,705,693]	-6	hSpCas9	negative selection	9264512
17112618	17112641	11	-	27260156	TOV112D	viability	TGTCCCCCTAAAAGTCACAATGG	PIK3C2A	ENSG00000011405	0.23219407706868958	[353]	[681,411,305,289]	4	hSpCas9	negative selection	9264513
17112637	17112660	11	+	27260156	TOV112D	viability	GACAGCATTAGAACTGAAGAAGG	PIK3C2A	ENSG00000011405	-0.09619763833307404	[89]	[48,107,61,119]	-2	hSpCas9	negative selection	9264514
17150497	17150520	11	+	27260156	TC71	viability	CCATCACACGTAAAAGTAACTGG	PIK3C2A	ENSG00000011405	-0.045231832087913815	[262]	[290,290,293,211]	-1	hSpCas9	negative selection	9321511
17150611	17150634	11	-	27260156	TC71	viability	ACCAATCACCGCACAAACCCAGG	PIK3C2A	ENSG00000011405	-0.22990438206565633	[1352]	[1286,1155,1230,1273]	-6	hSpCas9	negative selection	9321512
17145673	17145696	11	+	27260156	TC71	viability	TTTGAAGAGCCAGTTCTACTTGG	PIK3C2A	ENSG00000011405	0.2487932211419075	[1841]	[2259,2414,2092,2644]	6	hSpCas9	negative selection	9321513
17145682	17145705	11	-	27260156	TC71	viability	TTATCACAACCAAGTAGAACTGG	PIK3C2A	ENSG00000011405	-0.4046315466582318	[865]	[643,763,740,652]	-8	hSpCas9	negative selection	9385763
17112618	17112641	11	-	27260156	TC71	viability	TGTCCCCCTAAAAGTCACAATGG	PIK3C2A	ENSG00000011405	0.07917930857652083	[353]	[426,399,352,425]	2	hSpCas9	negative selection	9385764
17112637	17112660	11	+	27260156	TC71	viability	GACAGCATTAGAACTGAAGAAGG	PIK3C2A	ENSG00000011405	0.1519368936797756	[89]	[111,104,71,142]	4	hSpCas9	negative selection	9385765
17150497	17150520	11	+	27260156	TC32	viability	CCATCACACGTAAAAGTAACTGG	PIK3C2A	ENSG00000011405	0.27121223646408366	[262]	[331,194,480,229]	5	hSpCas9	negative selection	9442762
17150611	17150634	11	-	27260156	TC32	viability	ACCAATCACCGCACAAACCCAGG	PIK3C2A	ENSG00000011405	-0.06834438700906631	[1352]	[1039,1022,1701,1188]	-1	hSpCas9	negative selection	9442763
17145673	17145696	11	+	27260156	TC32	viability	TTTGAAGAGCCAGTTCTACTTGG	PIK3C2A	ENSG00000011405	0.3661518643229358	[1841]	[2154,1590,3056,2393]	6	hSpCas9	negative selection	9442764
17145682	17145705	11	-	27260156	TC32	viability	TTATCACAACCAAGTAGAACTGG	PIK3C2A	ENSG00000011405	-0.3714902436972287	[865]	[575,424,715,875]	-6	hSpCas9	negative selection	9507014
17112618	17112641	11	-	27260156	TC32	viability	TGTCCCCCTAAAAGTCACAATGG	PIK3C2A	ENSG00000011405	-0.018507384882553823	[353]	[370,197,407,377]	0	hSpCas9	negative selection	9507015
17112637	17112660	11	+	27260156	TC32	viability	GACAGCATTAGAACTGAAGAAGG	PIK3C2A	ENSG00000011405	0.3214012402239632	[89]	[64,97,173,98]	5	hSpCas9	negative selection	9507016
17119274	17119297	11	-	27869803	HPAFII	viability after 27 days	TAAGATCCCTAGCTGTGACCTGG	PIK3C2A	ENSG00000011405	-0.3186293288167312	[123]	[66,39,NaN]	-2	hSpCas9	negative selection	9540769
17119830	17119853	11	-	27869803	HPAFII	viability after 27 days	CTTACTCATTGCTTCACCAGTGG	PIK3C2A	ENSG00000011405	0.2542238358066784	[360]	[365,109,NaN]	2	hSpCas9	negative selection	9540770
17148731	17148754	11	+	27869803	HPAFII	viability after 27 days	AGTCATCATGTACCCAGCAAAGG	PIK3C2A	ENSG00000011405	-0.37409297870614994	[343]	[198,89,NaN]	-3	hSpCas9	negative selection	9540771
17150611	17150634	11	-	27869803	HPAFII	viability after 27 days	ACCAATCACCGCACAAACCCAGG	PIK3C2A	ENSG00000011405	-0.006255289835051359	[338]	[237,126,NaN]	0	hSpCas9	negative selection	9540772
17155595	17155618	11	-	27869803	HPAFII	viability after 27 days	GGGACCAGTAGTTTGCCAACTGG	PIK3C2A	ENSG00000011405	-1.4242104410736238	[70]	[2,22,NaN]	-7	hSpCas9	negative selection	9540773
17169113	17169136	11	-	27869803	HPAFII	viability after 27 days	GCCACACCCTTTCATCCACAAGG	PIK3C2A	ENSG00000011405	0.6212281657427952	[133]	[181,46,NaN]	5	hSpCas9	negative selection	9540774
17119274	17119297	11	-	27869803	HPAFII	viability after 15 days	TAAGATCCCTAGCTGTGACCTGG	PIK3C2A	ENSG00000011405	-0.010844323612614781	[123]	[151,119,NaN]	0	hSpCas9	negative selection	9623218
17119830	17119853	11	-	27869803	HPAFII	viability after 15 days	CTTACTCATTGCTTCACCAGTGG	PIK3C2A	ENSG00000011405	-0.3471722353666654	[360]	[460,207,NaN]	-4	hSpCas9	negative selection	9623219
17148731	17148754	11	+	27869803	HPAFII	viability after 15 days	AGTCATCATGTACCCAGCAAAGG	PIK3C2A	ENSG00000011405	-0.6820363734856806	[343]	[399,124,NaN]	-6	hSpCas9	negative selection	9623220
17150611	17150634	11	-	27869803	HPAFII	viability after 15 days	ACCAATCACCGCACAAACCCAGG	PIK3C2A	ENSG00000011405	0.2873194797956218	[338]	[673,301,NaN]	3	hSpCas9	negative selection	9623221
17155595	17155618	11	-	27869803	HPAFII	viability after 15 days	GGGACCAGTAGTTTGCCAACTGG	PIK3C2A	ENSG00000011405	0.15620920558690465	[70]	[68,94,NaN]	1	hSpCas9	negative selection	9623222
17169113	17169136	11	-	27869803	HPAFII	viability after 15 days	GCCACACCCTTTCATCCACAAGG	PIK3C2A	ENSG00000011405	0.9986042148410885	[133]	[452,184,NaN]	9	hSpCas9	negative selection	9623223
17119274	17119297	11	-	27869803	ASPC1	viability after 36 days	TAAGATCCCTAGCTGTGACCTGG	PIK3C2A	ENSG00000011405	-0.15856169185982416	[569]	[261,71,201]	-2	hSpCas9	negative selection	9705667
17119830	17119853	11	-	27869803	ASPC1	viability after 36 days	CTTACTCATTGCTTCACCAGTGG	PIK3C2A	ENSG00000011405	-0.26636836707607736	[1144]	[452,334,241]	-3	hSpCas9	negative selection	9705668
17148731	17148754	11	+	27869803	ASPC1	viability after 36 days	AGTCATCATGTACCCAGCAAAGG	PIK3C2A	ENSG00000011405	-0.334467947680061	[974]	[288,426,128]	-3	hSpCas9	negative selection	9705669
17150611	17150634	11	-	27869803	ASPC1	viability after 36 days	ACCAATCACCGCACAAACCCAGG	PIK3C2A	ENSG00000011405	0.27748616973101603	[1198]	[705,308,519]	2	hSpCas9	negative selection	9705670
17155595	17155618	11	-	27869803	ASPC1	viability after 36 days	GGGACCAGTAGTTTGCCAACTGG	PIK3C2A	ENSG00000011405	0.6013543273236309	[250]	[123,12,232]	6	hSpCas9	negative selection	9705671
17169113	17169136	11	-	27869803	ASPC1	viability after 36 days	GCCACACCCTTTCATCCACAAGG	PIK3C2A	ENSG00000011405	-0.2072823545415965	[472]	[154,156,121]	-2	hSpCas9	negative selection	9705672
17119274	17119297	11	-	27869803	PATU8988S	viability after 35 days	TAAGATCCCTAGCTGTGACCTGG	PIK3C2A	ENSG00000011405	-0.17708752291130392	[356]	[202,50,NaN]	-2	hSpCas9	negative selection	9788116
17119830	17119853	11	-	27869803	PATU8988S	viability after 35 days	CTTACTCATTGCTTCACCAGTGG	PIK3C2A	ENSG00000011405	-0.1079997224676903	[1056]	[395,393,NaN]	-1	hSpCas9	negative selection	9788117
17148731	17148754	11	+	27869803	PATU8988S	viability after 35 days	AGTCATCATGTACCCAGCAAAGG	PIK3C2A	ENSG00000011405	0.6333234960491476	[916]	[514,630,NaN]	7	hSpCas9	negative selection	9788118
17150611	17150634	11	-	27869803	PATU8988S	viability after 35 days	ACCAATCACCGCACAAACCCAGG	PIK3C2A	ENSG00000011405	-0.8992677693175328	[939]	[194,210,NaN]	-7	hSpCas9	negative selection	9788119
17155595	17155618	11	-	27869803	PATU8988S	viability after 35 days	GGGACCAGTAGTTTGCCAACTGG	PIK3C2A	ENSG00000011405	-1.0512108774305982	[236]	[72,18,NaN]	-7	hSpCas9	negative selection	9788120
17169113	17169136	11	-	27869803	PATU8988S	viability after 35 days	GCCACACCCTTTCATCCACAAGG	PIK3C2A	ENSG00000011405	-0.971194309810471	[578]	[95,141,NaN]	-7	hSpCas9	negative selection	9788121
17119274	17119297	11	-	27869803	PATU8988S	viability after 31 days	TAAGATCCCTAGCTGTGACCTGG	PIK3C2A	ENSG00000011405	-0.4472537011179316	[356]	[132,67,NaN]	-5	hSpCas9	negative selection	9870565
17119830	17119853	11	-	27869803	PATU8988S	viability after 31 days	CTTACTCATTGCTTCACCAGTGG	PIK3C2A	ENSG00000011405	0.04639110621439957	[1056]	[458,404,NaN]	0	hSpCas9	negative selection	9870566
17148731	17148754	11	+	27869803	PATU8988S	viability after 31 days	AGTCATCATGTACCCAGCAAAGG	PIK3C2A	ENSG00000011405	0.2888685562733644	[916]	[374,537,NaN]	3	hSpCas9	negative selection	9870567
17150611	17150634	11	-	27869803	PATU8988S	viability after 31 days	ACCAATCACCGCACAAACCCAGG	PIK3C2A	ENSG00000011405	-0.8692138515519389	[939]	[169,249,NaN]	-7	hSpCas9	negative selection	9870568
17155595	17155618	11	-	27869803	PATU8988S	viability after 31 days	GGGACCAGTAGTTTGCCAACTGG	PIK3C2A	ENSG00000011405	-1.36044663567165	[236]	[60,5,NaN]	-8	hSpCas9	negative selection	9870569
17169113	17169136	11	-	27869803	PATU8988S	viability after 31 days	GCCACACCCTTTCATCCACAAGG	PIK3C2A	ENSG00000011405	-0.9787992426284077	[578]	[44,208,NaN]	-7	hSpCas9	negative selection	9870570
17119274	17119297	11	-	27869803	HPAFII	viability after 35 days	TAAGATCCCTAGCTGTGACCTGG	PIK3C2A	ENSG00000011405	-1.3319056966315748	[123]	[15,34,NaN]	-6	hSpCas9	negative selection	9953014
17119830	17119853	11	-	27869803	HPAFII	viability after 35 days	CTTACTCATTGCTTCACCAGTGG	PIK3C2A	ENSG00000011405	-0.06669958689067534	[360]	[229,111,NaN]	0	hSpCas9	negative selection	9953015
17148731	17148754	11	+	27869803	HPAFII	viability after 35 days	AGTCATCATGTACCCAGCAAAGG	PIK3C2A	ENSG00000011405	-0.4552670303542665	[343]	[166,81,NaN]	-3	hSpCas9	negative selection	9953016
17150611	17150634	11	-	27869803	HPAFII	viability after 35 days	ACCAATCACCGCACAAACCCAGG	PIK3C2A	ENSG00000011405	0.25984454992351214	[338]	[236,169,NaN]	1	hSpCas9	negative selection	9953017
17155595	17155618	11	-	27869803	HPAFII	viability after 35 days	GGGACCAGTAGTTTGCCAACTGG	PIK3C2A	ENSG00000011405	-1.8548832067818095	[70]	[0,19,NaN]	-7	hSpCas9	negative selection	9953018
17169113	17169136	11	-	27869803	HPAFII	viability after 35 days	GCCACACCCTTTCATCCACAAGG	PIK3C2A	ENSG00000011405	0.510965614981234	[133]	[138,48,NaN]	3	hSpCas9	negative selection	9953019
17119274	17119297	11	-	27869803	HPAFII	viability after 31 days	TAAGATCCCTAGCTGTGACCTGG	PIK3C2A	ENSG00000011405	-2.349996064679127	[123]	[16,9,NaN]	-8	hSpCas9	negative selection	10035463
17119830	17119853	11	-	27869803	HPAFII	viability after 31 days	CTTACTCATTGCTTCACCAGTGG	PIK3C2A	ENSG00000011405	0.09688128721763367	[360]	[320,102,NaN]	0	hSpCas9	negative selection	10035464
17148731	17148754	11	+	27869803	HPAFII	viability after 31 days	AGTCATCATGTACCCAGCAAAGG	PIK3C2A	ENSG00000011405	-1.1907951114554947	[343]	[74,94,NaN]	-6	hSpCas9	negative selection	10035465
17150611	17150634	11	-	27869803	HPAFII	viability after 31 days	ACCAATCACCGCACAAACCCAGG	PIK3C2A	ENSG00000011405	0.08066501303013096	[338]	[238,159,NaN]	0	hSpCas9	negative selection	10035466
17155595	17155618	11	-	27869803	HPAFII	viability after 31 days	GGGACCAGTAGTTTGCCAACTGG	PIK3C2A	ENSG00000011405	-1.8504014553253554	[70]	[0,21,NaN]	-8	hSpCas9	negative selection	10035467
17169113	17169136	11	-	27869803	HPAFII	viability after 31 days	GCCACACCCTTTCATCCACAAGG	PIK3C2A	ENSG00000011405	0.03366700190936123	[133]	[109,40,NaN]	0	hSpCas9	negative selection	10035468
17169630	17169653	11	-	28162770	P31FUJ	viability	AGCATTACAGATGGAAGCAGAGG	PIK3C2A	ENSG00000011405	-0.2746223801090055	[69]	[67]	-3	hSpCas9	negative selection	10211287
17145918	17145941	11	-	28162770	P31FUJ	viability	AGAAGATGATGAAACACCCGTGG	PIK3C2A	ENSG00000011405	-0.1947628433952049	[523]	[537]	-2	hSpCas9	negative selection	10211288
17094357	17094380	11	-	28162770	P31FUJ	viability	GTAGTCCGAATTTTGAGGGAAGG	PIK3C2A	ENSG00000011405	0.41786354335760734	[92]	[145]	4	hSpCas9	negative selection	10211289
17169716	17169739	11	-	28162770	P31FUJ	viability	GCTCAGATATCTAGCAACAGCGG	PIK3C2A	ENSG00000011405	-0.18322017556381823	[285]	[295]	-2	hSpCas9	negative selection	10211290
17169581	17169604	11	-	28162770	P31FUJ	viability	CAAGTGACTGACAATCAGAGAGG	PIK3C2A	ENSG00000011405	-0.6113138276681084	[233]	[179]	-5	hSpCas9	negative selection	10211291
17169348	17169371	11	+	28162770	P31FUJ	viability	AGAGCTGTGCTGAAAAGGAAGGG	PIK3C2A	ENSG00000011405	-0.8584066896328806	[53]	[34]	-6	hSpCas9	negative selection	10211292
17168886	17168909	11	-	28162770	P31FUJ	viability	GCCTAAGGTGGATAATGTGGAGG	PIK3C2A	ENSG00000011405	0.2656513030521028	[377]	[533]	3	hSpCas9	negative selection	10211293
17168691	17168714	11	-	28162770	P31FUJ	viability	AACTCAGCTTGCAAAAGCCCAGG	PIK3C2A	ENSG00000011405	0.48873334918222144	[187]	[309]	5	hSpCas9	negative selection	10211294
17155551	17155574	11	-	28162770	P31FUJ	viability	TGAAGTACAGAATGAGGAGATGG	PIK3C2A	ENSG00000011405	-0.7281274926508583	[116]	[82]	-5	hSpCas9	negative selection	10211295
17150611	17150634	11	-	28162770	P31FUJ	viability	ACCAATCACCGCACAAACCCAGG	PIK3C2A	ENSG00000011405	-0.21008212791429526	[62]	[63]	-2	hSpCas9	negative selection	10211296
17169630	17169653	11	-	28162770	TF1	viability	AGCATTACAGATGGAAGCAGAGG	PIK3C2A	ENSG00000011405	NaN	[NaN]	[89]	1	hSpCas9	negative selection	10380653
17145918	17145941	11	-	28162770	TF1	viability	AGAAGATGATGAAACACCCGTGG	PIK3C2A	ENSG00000011405	NaN	[NaN]	[628]	1	hSpCas9	negative selection	10380654
17094357	17094380	11	-	28162770	TF1	viability	GTAGTCCGAATTTTGAGGGAAGG	PIK3C2A	ENSG00000011405	NaN	[NaN]	[220]	1	hSpCas9	negative selection	10380655
17169716	17169739	11	-	28162770	TF1	viability	GCTCAGATATCTAGCAACAGCGG	PIK3C2A	ENSG00000011405	NaN	[NaN]	[130]	1	hSpCas9	negative selection	10380656
17169581	17169604	11	-	28162770	TF1	viability	CAAGTGACTGACAATCAGAGAGG	PIK3C2A	ENSG00000011405	NaN	[NaN]	[183]	1	hSpCas9	negative selection	10380657
17169348	17169371	11	+	28162770	TF1	viability	AGAGCTGTGCTGAAAAGGAAGGG	PIK3C2A	ENSG00000011405	NaN	[NaN]	[108]	1	hSpCas9	negative selection	10380658
17168886	17168909	11	-	28162770	TF1	viability	GCCTAAGGTGGATAATGTGGAGG	PIK3C2A	ENSG00000011405	NaN	[NaN]	[430]	1	hSpCas9	negative selection	10380659
17168691	17168714	11	-	28162770	TF1	viability	AACTCAGCTTGCAAAAGCCCAGG	PIK3C2A	ENSG00000011405	NaN	[NaN]	[250]	1	hSpCas9	negative selection	10380660
17155551	17155574	11	-	28162770	TF1	viability	TGAAGTACAGAATGAGGAGATGG	PIK3C2A	ENSG00000011405	NaN	[NaN]	[49]	1	hSpCas9	negative selection	10380661
17150611	17150634	11	-	28162770	TF1	viability	ACCAATCACCGCACAAACCCAGG	PIK3C2A	ENSG00000011405	NaN	[NaN]	[12]	1	hSpCas9	negative selection	10380662
17169630	17169653	11	-	28162770	SKM1	viability	AGCATTACAGATGGAAGCAGAGG	PIK3C2A	ENSG00000011405	0.7085130186767743	[17]	[51]	6	hSpCas9	negative selection	10550019
17145918	17145941	11	-	28162770	SKM1	viability	AGAAGATGATGAAACACCCGTGG	PIK3C2A	ENSG00000011405	0.504808618245103	[117]	[295]	5	hSpCas9	negative selection	10550020
17094357	17094380	11	-	28162770	SKM1	viability	GTAGTCCGAATTTTGAGGGAAGG	PIK3C2A	ENSG00000011405	1.5344836189017252	[32]	[168]	9	hSpCas9	negative selection	10550021
17169716	17169739	11	-	28162770	SKM1	viability	GCTCAGATATCTAGCAACAGCGG	PIK3C2A	ENSG00000011405	0.5630232321903987	[84]	[221]	5	hSpCas9	negative selection	10550022
17169581	17169604	11	-	28162770	SKM1	viability	CAAGTGACTGACAATCAGAGAGG	PIK3C2A	ENSG00000011405	0.1663164969303591	[61]	[122]	1	hSpCas9	negative selection	10550023
17169348	17169371	11	+	28162770	SKM1	viability	AGAGCTGTGCTGAAAAGGAAGGG	PIK3C2A	ENSG00000011405	-0.18457177740671415	[8]	[13]	-1	hSpCas9	negative selection	10550024
17168886	17168909	11	-	28162770	SKM1	viability	GCCTAAGGTGGATAATGTGGAGG	PIK3C2A	ENSG00000011405	0.748010461233179	[96]	[287]	7	hSpCas9	negative selection	10550025
17168691	17168714	11	-	28162770	SKM1	viability	AACTCAGCTTGCAAAAGCCCAGG	PIK3C2A	ENSG00000011405	0.703089346721752	[40]	[117]	6	hSpCas9	negative selection	10550026
17155551	17155574	11	-	28162770	SKM1	viability	TGAAGTACAGAATGAGGAGATGG	PIK3C2A	ENSG00000011405	-1.1699250014423126	[41]	[32]	-7	hSpCas9	negative selection	10550027
17150611	17150634	11	-	28162770	SKM1	viability	ACCAATCACCGCACAAACCCAGG	PIK3C2A	ENSG00000011405	-1.1845717774067142	[8]	[6]	-7	hSpCas9	negative selection	10550028
17169630	17169653	11	-	28162770	SKM1	viability	AGCATTACAGATGGAAGCAGAGG	PIK3C2A	ENSG00000011405	0.7085130186767743	[17]	[51]	6	hSpCas9	negative selection	10719385
17145918	17145941	11	-	28162770	SKM1	viability	AGAAGATGATGAAACACCCGTGG	PIK3C2A	ENSG00000011405	0.504808618245103	[117]	[295]	5	hSpCas9	negative selection	10719386
17094357	17094380	11	-	28162770	SKM1	viability	GTAGTCCGAATTTTGAGGGAAGG	PIK3C2A	ENSG00000011405	1.5344836189017252	[32]	[168]	9	hSpCas9	negative selection	10719387
17169716	17169739	11	-	28162770	SKM1	viability	GCTCAGATATCTAGCAACAGCGG	PIK3C2A	ENSG00000011405	0.5630232321903987	[84]	[221]	5	hSpCas9	negative selection	10719388
17169581	17169604	11	-	28162770	SKM1	viability	CAAGTGACTGACAATCAGAGAGG	PIK3C2A	ENSG00000011405	0.1663164969303591	[61]	[122]	1	hSpCas9	negative selection	10719389
17169348	17169371	11	+	28162770	SKM1	viability	AGAGCTGTGCTGAAAAGGAAGGG	PIK3C2A	ENSG00000011405	-0.18457177740671415	[8]	[13]	-1	hSpCas9	negative selection	10719390
17168886	17168909	11	-	28162770	SKM1	viability	GCCTAAGGTGGATAATGTGGAGG	PIK3C2A	ENSG00000011405	0.748010461233179	[96]	[287]	7	hSpCas9	negative selection	10719391
17168691	17168714	11	-	28162770	SKM1	viability	AACTCAGCTTGCAAAAGCCCAGG	PIK3C2A	ENSG00000011405	0.703089346721752	[40]	[117]	6	hSpCas9	negative selection	10719392
17155551	17155574	11	-	28162770	SKM1	viability	TGAAGTACAGAATGAGGAGATGG	PIK3C2A	ENSG00000011405	-1.1699250014423126	[41]	[32]	-7	hSpCas9	negative selection	10719393
17150611	17150634	11	-	28162770	SKM1	viability	ACCAATCACCGCACAAACCCAGG	PIK3C2A	ENSG00000011405	-1.1845717774067142	[8]	[6]	-7	hSpCas9	negative selection	10719394
17169630	17169653	11	-	28162770	PL21	viability	AGCATTACAGATGGAAGCAGAGG	PIK3C2A	ENSG00000011405	0.878211519601958	[64]	[51]	7	hSpCas9	negative selection	10888751
17145918	17145941	11	-	28162770	PL21	viability	AGAAGATGATGAAACACCCGTGG	PIK3C2A	ENSG00000011405	-0.8152904260802858	[375]	[92]	-5	hSpCas9	negative selection	10888752
17094357	17094380	11	-	28162770	PL21	viability	GTAGTCCGAATTTTGAGGGAAGG	PIK3C2A	ENSG00000011405	0.20013961448932	[181]	[90]	1	hSpCas9	negative selection	10888753
17169716	17169739	11	-	28162770	PL21	viability	GCTCAGATATCTAGCAACAGCGG	PIK3C2A	ENSG00000011405	-0.1845242357460049	[281]	[107]	-1	hSpCas9	negative selection	10888754
17169581	17169604	11	-	28162770	PL21	viability	CAAGTGACTGACAATCAGAGAGG	PIK3C2A	ENSG00000011405	-0.08088053681783602	[225]	[92]	0	hSpCas9	negative selection	10888755
17169348	17169371	11	+	28162770	PL21	viability	AGAGCTGTGCTGAAAAGGAAGGG	PIK3C2A	ENSG00000011405	2.8078221917105597	[20]	[63]	9	hSpCas9	negative selection	10888756
17168886	17168909	11	-	28162770	PL21	viability	GCCTAAGGTGGATAATGTGGAGG	PIK3C2A	ENSG00000011405	0.2432083363812062	[230]	[118]	2	hSpCas9	negative selection	10888757
17168691	17168714	11	-	28162770	PL21	viability	AACTCAGCTTGCAAAAGCCCAGG	PIK3C2A	ENSG00000011405	-0.4736321531896921	[133]	[41]	-3	hSpCas9	negative selection	10888758
17155551	17155574	11	-	28162770	PL21	viability	TGAAGTACAGAATGAGGAGATGG	PIK3C2A	ENSG00000011405	-0.7592184010133339	[104]	[26]	-5	hSpCas9	negative selection	10888759
17150611	17150634	11	-	28162770	PL21	viability	ACCAATCACCGCACAAACCCAGG	PIK3C2A	ENSG00000011405	-1.3605753399851588	[58]	[9]	-7	hSpCas9	negative selection	10888760
17169630	17169653	11	-	28162770	P31FUJ	viability	AGCATTACAGATGGAAGCAGAGG	PIK3C2A	ENSG00000011405	-0.2746223801090055	[69]	[67]	-3	hSpCas9	negative selection	11058117
17145918	17145941	11	-	28162770	P31FUJ	viability	AGAAGATGATGAAACACCCGTGG	PIK3C2A	ENSG00000011405	-0.1947628433952049	[523]	[537]	-2	hSpCas9	negative selection	11058118
17094357	17094380	11	-	28162770	P31FUJ	viability	GTAGTCCGAATTTTGAGGGAAGG	PIK3C2A	ENSG00000011405	0.41786354335760734	[92]	[145]	4	hSpCas9	negative selection	11058119
17169716	17169739	11	-	28162770	P31FUJ	viability	GCTCAGATATCTAGCAACAGCGG	PIK3C2A	ENSG00000011405	-0.18322017556381823	[285]	[295]	-2	hSpCas9	negative selection	11058120
17169581	17169604	11	-	28162770	P31FUJ	viability	CAAGTGACTGACAATCAGAGAGG	PIK3C2A	ENSG00000011405	-0.6113138276681084	[233]	[179]	-5	hSpCas9	negative selection	11058121
17169348	17169371	11	+	28162770	P31FUJ	viability	AGAGCTGTGCTGAAAAGGAAGGG	PIK3C2A	ENSG00000011405	-0.8584066896328806	[53]	[34]	-6	hSpCas9	negative selection	11058122
17168886	17168909	11	-	28162770	P31FUJ	viability	GCCTAAGGTGGATAATGTGGAGG	PIK3C2A	ENSG00000011405	0.2656513030521028	[377]	[533]	3	hSpCas9	negative selection	11058123
17168691	17168714	11	-	28162770	P31FUJ	viability	AACTCAGCTTGCAAAAGCCCAGG	PIK3C2A	ENSG00000011405	0.48873334918222144	[187]	[309]	5	hSpCas9	negative selection	11058124
17155551	17155574	11	-	28162770	P31FUJ	viability	TGAAGTACAGAATGAGGAGATGG	PIK3C2A	ENSG00000011405	-0.7281274926508583	[116]	[82]	-5	hSpCas9	negative selection	11058125
17150611	17150634	11	-	28162770	P31FUJ	viability	ACCAATCACCGCACAAACCCAGG	PIK3C2A	ENSG00000011405	-0.21008212791429526	[62]	[63]	-2	hSpCas9	negative selection	11058126
17169630	17169653	11	-	28162770	OCIAML5	viability	AGCATTACAGATGGAAGCAGAGG	PIK3C2A	ENSG00000011405	-0.6027071019272798	[52]	[62]	-4	hSpCas9	negative selection	11227483
17145918	17145941	11	-	28162770	OCIAML5	viability	AGAAGATGATGAAACACCCGTGG	PIK3C2A	ENSG00000011405	-0.3684647851020817	[338]	[473]	-3	hSpCas9	negative selection	11227484
17094357	17094380	11	-	28162770	OCIAML5	viability	GTAGTCCGAATTTTGAGGGAAGG	PIK3C2A	ENSG00000011405	-0.27452154170532367	[129]	[193]	-2	hSpCas9	negative selection	11227485
17169716	17169739	11	-	28162770	OCIAML5	viability	GCTCAGATATCTAGCAACAGCGG	PIK3C2A	ENSG00000011405	0.6402649519468948	[133]	[376]	5	hSpCas9	negative selection	11227486
17169581	17169604	11	-	28162770	OCIAML5	viability	CAAGTGACTGACAATCAGAGAGG	PIK3C2A	ENSG00000011405	-0.4428114241791593	[124]	[165]	-3	hSpCas9	negative selection	11227487
17169348	17169371	11	+	28162770	OCIAML5	viability	AGAGCTGTGCTGAAAAGGAAGGG	PIK3C2A	ENSG00000011405	-0.6081409879779076	[37]	[44]	-4	hSpCas9	negative selection	11227488
17168886	17168909	11	-	28162770	OCIAML5	viability	GCCTAAGGTGGATAATGTGGAGG	PIK3C2A	ENSG00000011405	0.24604351458585083	[269]	[577]	2	hSpCas9	negative selection	11227489
17168691	17168714	11	-	28162770	OCIAML5	viability	AACTCAGCTTGCAAAAGCCCAGG	PIK3C2A	ENSG00000011405	0.30188479437057475	[110]	[246]	2	hSpCas9	negative selection	11227490
17155551	17155574	11	-	28162770	OCIAML5	viability	TGAAGTACAGAATGAGGAGATGG	PIK3C2A	ENSG00000011405	-0.13986888184673296	[93]	[153]	-1	hSpCas9	negative selection	11227491
17150611	17150634	11	-	28162770	OCIAML5	viability	ACCAATCACCGCACAAACCCAGG	PIK3C2A	ENSG00000011405	0.7073608377500218	[18]	[55]	6	hSpCas9	negative selection	11227492
17169630	17169653	11	-	28162770	EOL1	viability	AGCATTACAGATGGAAGCAGAGG	PIK3C2A	ENSG00000011405	-1.7299556624036985	[169]	[26]	-8	hSpCas9	negative selection	11396849
17145918	17145941	11	-	28162770	EOL1	viability	AGAAGATGATGAAACACCCGTGG	PIK3C2A	ENSG00000011405	0.3697107285270491	[544]	[370]	3	hSpCas9	negative selection	11396850
17094357	17094380	11	-	28162770	EOL1	viability	GTAGTCCGAATTTTGAGGGAAGG	PIK3C2A	ENSG00000011405	-0.6094308004318167	[277]	[95]	-4	hSpCas9	negative selection	11396851
17169716	17169739	11	-	28162770	EOL1	viability	GCTCAGATATCTAGCAACAGCGG	PIK3C2A	ENSG00000011405	0.8966956509306472	[522]	[512]	7	hSpCas9	negative selection	11396852
17169581	17169604	11	-	28162770	EOL1	viability	CAAGTGACTGACAATCAGAGAGG	PIK3C2A	ENSG00000011405	1.4093647086277454	[337]	[472]	9	hSpCas9	negative selection	11396853
17169348	17169371	11	+	28162770	EOL1	viability	AGAGCTGTGCTGAAAAGGAAGGG	PIK3C2A	ENSG00000011405	-0.7657677292968503	[70]	[21]	-5	hSpCas9	negative selection	11396854
17168886	17168909	11	-	28162770	EOL1	viability	GCCTAAGGTGGATAATGTGGAGG	PIK3C2A	ENSG00000011405	0.28513748682700196	[323]	[207]	2	hSpCas9	negative selection	11396855
17168691	17168714	11	-	28162770	EOL1	viability	AACTCAGCTTGCAAAAGCCCAGG	PIK3C2A	ENSG00000011405	0.4190831911637479	[202]	[142]	4	hSpCas9	negative selection	11396856
17155551	17155574	11	-	28162770	EOL1	viability	TGAAGTACAGAATGAGGAGATGG	PIK3C2A	ENSG00000011405	0.2858140144083975	[122]	[78]	2	hSpCas9	negative selection	11396857
17150611	17150634	11	-	28162770	EOL1	viability	ACCAATCACCGCACAAACCCAGG	PIK3C2A	ENSG00000011405	0.5766244681502277	[55]	[43]	5	hSpCas9	negative selection	11396858
17169630	17169653	11	-	28162770	MOLM13	viability	AGCATTACAGATGGAAGCAGAGG	PIK3C2A	ENSG00000011405	-0.3621856170131088	[143]	[80]	-2	hSpCas9	negative selection	11566215
17145918	17145941	11	-	28162770	MOLM13	viability	AGAAGATGATGAAACACCCGTGG	PIK3C2A	ENSG00000011405	-0.7537423252786526	[631]	[270]	-4	hSpCas9	negative selection	11566216
17094357	17094380	11	-	28162770	MOLM13	viability	GTAGTCCGAATTTTGAGGGAAGG	PIK3C2A	ENSG00000011405	0.5698890950469742	[272]	[292]	4	hSpCas9	negative selection	11566217
17169716	17169739	11	-	28162770	MOLM13	viability	GCTCAGATATCTAGCAACAGCGG	PIK3C2A	ENSG00000011405	0.4063509712354464	[454]	[435]	3	hSpCas9	negative selection	11566218
17169581	17169604	11	-	28162770	MOLM13	viability	CAAGTGACTGACAATCAGAGAGG	PIK3C2A	ENSG00000011405	0.4248206596526928	[305]	[296]	3	hSpCas9	negative selection	11566219
17169348	17169371	11	+	28162770	MOLM13	viability	AGAGCTGTGCTGAAAAGGAAGGG	PIK3C2A	ENSG00000011405	1.5636483643500096	[50]	[108]	9	hSpCas9	negative selection	11566220
17168886	17168909	11	-	28162770	MOLM13	viability	GCCTAAGGTGGATAATGTGGAGG	PIK3C2A	ENSG00000011405	-0.9833217302877499	[349]	[127]	-5	hSpCas9	negative selection	11566221
17168691	17168714	11	-	28162770	MOLM13	viability	AACTCAGCTTGCAAAAGCCCAGG	PIK3C2A	ENSG00000011405	-0.22941199504811158	[286]	[176]	-1	hSpCas9	negative selection	11566222
17155551	17155574	11	-	28162770	MOLM13	viability	TGAAGTACAGAATGAGGAGATGG	PIK3C2A	ENSG00000011405	-0.15630828245967765	[204]	[132]	-1	hSpCas9	negative selection	11566223
17150611	17150634	11	-	28162770	MOLM13	viability	ACCAATCACCGCACAAACCCAGG	PIK3C2A	ENSG00000011405	-6.339465540513025	[111]	[0]	-9	hSpCas9	negative selection	11566224
17169630	17169653	11	-	28162770	HEL	viability	AGCATTACAGATGGAAGCAGAGG	PIK3C2A	ENSG00000011405	1.0833114233863381	[83]	[113]	8	hSpCas9	negative selection	11735581
17145918	17145941	11	-	28162770	HEL	viability	AGAAGATGATGAAACACCCGTGG	PIK3C2A	ENSG00000011405	0.08233343552317962	[465]	[315]	0	hSpCas9	negative selection	11735582
17094357	17094380	11	-	28162770	HEL	viability	GTAGTCCGAATTTTGAGGGAAGG	PIK3C2A	ENSG00000011405	0.3098949596338109	[198]	[157]	2	hSpCas9	negative selection	11735583
17169716	17169739	11	-	28162770	HEL	viability	GCTCAGATATCTAGCAACAGCGG	PIK3C2A	ENSG00000011405	0.6638004475281867	[407]	[413]	5	hSpCas9	negative selection	11735584
17169581	17169604	11	-	28162770	HEL	viability	CAAGTGACTGACAATCAGAGAGG	PIK3C2A	ENSG00000011405	0.721540399707955	[284]	[300]	6	hSpCas9	negative selection	11735585
17169348	17169371	11	+	28162770	HEL	viability	AGAGCTGTGCTGAAAAGGAAGGG	PIK3C2A	ENSG00000011405	1.7682697140842158	[43]	[95]	9	hSpCas9	negative selection	11735586
17168886	17168909	11	-	28162770	HEL	viability	GCCTAAGGTGGATAATGTGGAGG	PIK3C2A	ENSG00000011405	0.051263024320526374	[332]	[220]	0	hSpCas9	negative selection	11735587
17168691	17168714	11	-	28162770	HEL	viability	AACTCAGCTTGCAAAAGCCCAGG	PIK3C2A	ENSG00000011405	-0.8400432739143212	[217]	[77]	-5	hSpCas9	negative selection	11735588
17155551	17155574	11	-	28162770	HEL	viability	TGAAGTACAGAATGAGGAGATGG	PIK3C2A	ENSG00000011405	0.8479639701919354	[156]	[180]	7	hSpCas9	negative selection	11735589
17150611	17150634	11	-	28162770	HEL	viability	ACCAATCACCGCACAAACCCAGG	PIK3C2A	ENSG00000011405	0.3726496686326126	[81]	[67]	3	hSpCas9	negative selection	11735590
17169630	17169653	11	-	28162770	MV411	viability	AGCATTACAGATGGAAGCAGAGG	PIK3C2A	ENSG00000011405	0.011370192549250868	[52]	[44]	0	hSpCas9	negative selection	11904947
17145918	17145941	11	-	28162770	MV411	viability	AGAAGATGATGAAACACCCGTGG	PIK3C2A	ENSG00000011405	-0.3020602692835772	[441]	[301]	-2	hSpCas9	negative selection	11904948
17094357	17094380	11	-	28162770	MV411	viability	GTAGTCCGAATTTTGAGGGAAGG	PIK3C2A	ENSG00000011405	0.8894547408937188	[156]	[244]	7	hSpCas9	negative selection	11904949
17169716	17169739	11	-	28162770	MV411	viability	GCTCAGATATCTAGCAACAGCGG	PIK3C2A	ENSG00000011405	-0.1734055701772742	[331]	[247]	-1	hSpCas9	negative selection	11904950
17169581	17169604	11	-	28162770	MV411	viability	CAAGTGACTGACAATCAGAGAGG	PIK3C2A	ENSG00000011405	-0.09677861130637168	[211]	[166]	0	hSpCas9	negative selection	11904951
17169348	17169371	11	+	28162770	MV411	viability	AGAGCTGTGCTGAAAAGGAAGGG	PIK3C2A	ENSG00000011405	2.2918316701412285	[23]	[98]	9	hSpCas9	negative selection	11904952
17168886	17168909	11	-	28162770	MV411	viability	GCCTAAGGTGGATAATGTGGAGG	PIK3C2A	ENSG00000011405	0.8305841984751716	[264]	[396]	7	hSpCas9	negative selection	11904953
17168691	17168714	11	-	28162770	MV411	viability	AACTCAGCTTGCAAAAGCCCAGG	PIK3C2A	ENSG00000011405	-0.10305969630135803	[152]	[119]	-1	hSpCas9	negative selection	11904954
17155551	17155574	11	-	28162770	MV411	viability	TGAAGTACAGAATGAGGAGATGG	PIK3C2A	ENSG00000011405	-0.5599173712748287	[90]	[51]	-4	hSpCas9	negative selection	11904955
17150611	17150634	11	-	28162770	MV411	viability	ACCAATCACCGCACAAACCCAGG	PIK3C2A	ENSG00000011405	-0.2264936375496367	[49]	[35]	-2	hSpCas9	negative selection	11904956
17169630	17169653	11	-	28162770	MONOMAC1	viability	AGCATTACAGATGGAAGCAGAGG	PIK3C2A	ENSG00000011405	-0.26520834970113294	[64]	[61]	-2	hSpCas9	negative selection	12074313
17145918	17145941	11	-	28162770	MONOMAC1	viability	AGAAGATGATGAAACACCCGTGG	PIK3C2A	ENSG00000011405	0.17652401624313097	[246]	[319]	1	hSpCas9	negative selection	12074314
17094357	17094380	11	-	28162770	MONOMAC1	viability	GTAGTCCGAATTTTGAGGGAAGG	PIK3C2A	ENSG00000011405	-0.16020007887918233	[115]	[118]	-1	hSpCas9	negative selection	12074315
17169716	17169739	11	-	28162770	MONOMAC1	viability	GCTCAGATATCTAGCAACAGCGG	PIK3C2A	ENSG00000011405	0.35935650146483167	[186]	[274]	3	hSpCas9	negative selection	12074316
17169581	17169604	11	-	28162770	MONOMAC1	viability	CAAGTGACTGACAATCAGAGAGG	PIK3C2A	ENSG00000011405	-0.2636345957885775	[132]	[126]	-2	hSpCas9	negative selection	12074317
17169348	17169371	11	+	28162770	MONOMAC1	viability	AGAGCTGTGCTGAAAAGGAAGGG	PIK3C2A	ENSG00000011405	1.16051515755853	[15]	[40]	8	hSpCas9	negative selection	12074318
17168886	17168909	11	-	28162770	MONOMAC1	viability	GCCTAAGGTGGATAATGTGGAGG	PIK3C2A	ENSG00000011405	0.3092423039691241	[156]	[222]	3	hSpCas9	negative selection	12074319
17168691	17168714	11	-	28162770	MONOMAC1	viability	AACTCAGCTTGCAAAAGCCCAGG	PIK3C2A	ENSG00000011405	0.1899862760496935	[90]	[118]	2	hSpCas9	negative selection	12074320
17155551	17155574	11	-	28162770	MONOMAC1	viability	TGAAGTACAGAATGAGGAGATGG	PIK3C2A	ENSG00000011405	-0.29115902442410363	[94]	[88]	-3	hSpCas9	negative selection	12074321
17150611	17150634	11	-	28162770	MONOMAC1	viability	ACCAATCACCGCACAAACCCAGG	PIK3C2A	ENSG00000011405	-0.9340024412257599	[19]	[11]	-6	hSpCas9	negative selection	12074322
17169630	17169653	11	-	28162770	OCIAML2	viability	AGCATTACAGATGGAAGCAGAGG	PIK3C2A	ENSG00000011405	-0.08816018841974826	[13]	[72]	0	hSpCas9	negative selection	12243679
17145918	17145941	11	-	28162770	OCIAML2	viability	AGAAGATGATGAAACACCCGTGG	PIK3C2A	ENSG00000011405	-0.06853138167081552	[69]	[369]	0	hSpCas9	negative selection	12243680
17094357	17094380	11	-	28162770	OCIAML2	viability	GTAGTCCGAATTTTGAGGGAAGG	PIK3C2A	ENSG00000011405	2.3740236382384188	[14]	[430]	9	hSpCas9	negative selection	12243681
17169716	17169739	11	-	28162770	OCIAML2	viability	GCTCAGATATCTAGCAACAGCGG	PIK3C2A	ENSG00000011405	0.39930963419346566	[57]	[423]	4	hSpCas9	negative selection	12243682
17169581	17169604	11	-	28162770	OCIAML2	viability	CAAGTGACTGACAATCAGAGAGG	PIK3C2A	ENSG00000011405	1.073690690981649	[32]	[384]	8	hSpCas9	negative selection	12243683
17169348	17169371	11	+	28162770	OCIAML2	viability	AGAGCTGTGCTGAAAAGGAAGGG	PIK3C2A	ENSG00000011405	-0.9925825284375169	[13]	[38]	-6	hSpCas9	negative selection	12243684
17168886	17168909	11	-	28162770	OCIAML2	viability	GCCTAAGGTGGATAATGTGGAGG	PIK3C2A	ENSG00000011405	-0.18732302438210624	[52]	[257]	-1	hSpCas9	negative selection	12243685
17168691	17168714	11	-	28162770	OCIAML2	viability	AACTCAGCTTGCAAAAGCCCAGG	PIK3C2A	ENSG00000011405	-0.2779847472997653	[20]	[95]	-2	hSpCas9	negative selection	12243686
17155551	17155574	11	-	28162770	OCIAML2	viability	TGAAGTACAGAATGAGGAGATGG	PIK3C2A	ENSG00000011405	-0.6980403213452337	[23]	[81]	-5	hSpCas9	negative selection	12243687
17150611	17150634	11	-	28162770	OCIAML2	viability	ACCAATCACCGCACAAACCCAGG	PIK3C2A	ENSG00000011405	-1.0035038148148632	[16]	[46]	-6	hSpCas9	negative selection	12243688
17169630	17169653	11	-	28162770	OCIAML3	viability	AGCATTACAGATGGAAGCAGAGG	PIK3C2A	ENSG00000011405	0.04984854945056161	[15]	[49]	0	hSpCas9	negative selection	12413045
17145918	17145941	11	-	28162770	OCIAML3	viability	AGAAGATGATGAAACACCCGTGG	PIK3C2A	ENSG00000011405	-0.9747519620491293	[96]	[148]	-6	hSpCas9	negative selection	12413046
17094357	17094380	11	-	28162770	OCIAML3	viability	GTAGTCCGAATTTTGAGGGAAGG	PIK3C2A	ENSG00000011405	0.9580902264913664	[36]	[216]	8	hSpCas9	negative selection	12413047
17169716	17169739	11	-	28162770	OCIAML3	viability	GCTCAGATATCTAGCAACAGCGG	PIK3C2A	ENSG00000011405	-0.4168799527234973	[110]	[250]	-3	hSpCas9	negative selection	12413048
17169581	17169604	11	-	28162770	OCIAML3	viability	CAAGTGACTGACAATCAGAGAGG	PIK3C2A	ENSG00000011405	1.521469577095773	[65]	[571]	9	hSpCas9	negative selection	12413049
17169348	17169371	11	+	28162770	OCIAML3	viability	AGAGCTGTGCTGAAAAGGAAGGG	PIK3C2A	ENSG00000011405	-2.8164000616606115	[13]	[5]	-9	hSpCas9	negative selection	12413050
17168886	17168909	11	-	28162770	OCIAML3	viability	GCCTAAGGTGGATAATGTGGAGG	PIK3C2A	ENSG00000011405	0.3284557592048164	[85]	[325]	3	hSpCas9	negative selection	12413051
17168691	17168714	11	-	28162770	OCIAML3	viability	AACTCAGCTTGCAAAAGCCCAGG	PIK3C2A	ENSG00000011405	-0.021117971903582056	[39]	[118]	0	hSpCas9	negative selection	12413052
17155551	17155574	11	-	28162770	OCIAML3	viability	TGAAGTACAGAATGAGGAGATGG	PIK3C2A	ENSG00000011405	-0.21961212554266518	[26]	[69]	-2	hSpCas9	negative selection	12413053
17150611	17150634	11	-	28162770	OCIAML3	viability	ACCAATCACCGCACAAACCCAGG	PIK3C2A	ENSG00000011405	1.0434222802911288	[8]	[55]	8	hSpCas9	negative selection	12413054