Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:5296
• Symbol:PIK3R2
• Description:phosphoinositide-3-kinase regulatory subunit 2

DataSource: http://genomecrispr.dkfz.de/#!/results/PIK3R2

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
18156021	18156044	19	+	26472758	Jiyoye	viability	GAGCGCTGCCCACAGAGCGTGGG	PIK3R2	ENSG00000268173	-0.014651283435609397	[70]	[52]	0	hSpCas9	negative selection	120768
18162411	18162434	19	+	26472758	Jiyoye	viability	GGAGGTGAACGAGAAACTCCGGG	PIK3R2	ENSG00000268173	5.494638222756212	[0]	[33]	9	hSpCas9	negative selection	120769
18162017	18162040	19	+	26472758	Jiyoye	viability	GGAACACTTGGAAGAGCAGGAGG	PIK3R2	ENSG00000268173	0.3752324890031191	[136]	[133]	3	hSpCas9	negative selection	120770
18163277	18163300	19	+	26472758	Jiyoye	viability	GGAGGACAGCGTGGAGGCAGTGG	PIK3R2	ENSG00000268173	-2.2366808082688516	[149]	[23]	-8	hSpCas9	negative selection	120771
18166281	18166304	19	+	26472758	Jiyoye	viability	GCAACGAGAAAGAGATGCAAAGG	PIK3R2	ENSG00000268173	1.5033906967651767	[28]	[61]	8	hSpCas9	negative selection	120772
18168789	18168812	19	+	26472758	Jiyoye	viability	GGGCAAGATCAACCGCACGCAGG	PIK3R2	ENSG00000268173	6.214530303563477	[0]	[55]	9	hSpCas9	negative selection	120773
18155878	18155901	19	-	26472758	Jiyoye	viability	GAAGCCCTCAGGGCCCGCCATGG	PIK3R2	ENSG00000268173	-0.6479661726865873	[159]	[76]	-4	hSpCas9	negative selection	120774
18155966	18155989	19	+	26472758	Jiyoye	viability	CGTGCTGGTAGTGAGCCGGGCGG	PIK3R2	ENSG00000268173	-0.7584106842121016	[82]	[36]	-5	hSpCas9	negative selection	120775
18156089	18156112	19	-	26472758	Jiyoye	viability	GGAACTCCACATAGGTGCCAGGG	PIK3R2	ENSG00000268173	0.3950006675597711	[118]	[117]	3	hSpCas9	negative selection	120776
18160481	18160504	19	-	26472758	Jiyoye	viability	AGAACTGCTCGGGCAAGTCGGGG	PIK3R2	ENSG00000268173	-0.5624509694506078	[140]	[71]	-4	hSpCas9	negative selection	120777
18156021	18156044	19	+	26472758	KBM7	viability	GAGCGCTGCCCACAGAGCGTGGG	PIK3R2	ENSG00000268173	-0.24410245135170494	[277,187]	[135,50]	-2	hSpCas9	negative selection	311886
18162411	18162434	19	+	26472758	KBM7	viability	GGAGGTGAACGAGAAACTCCGGG	PIK3R2	ENSG00000268173	0.8957661958732572	[48,49]	[32,52]	8	hSpCas9	negative selection	311887
18162017	18162040	19	+	26472758	KBM7	viability	GGAACACTTGGAAGAGCAGGAGG	PIK3R2	ENSG00000268173	0.6991562882185012	[713,435]	[274,568]	7	hSpCas9	negative selection	311888
18163277	18163300	19	+	26472758	KBM7	viability	GGAGGACAGCGTGGAGGCAGTGG	PIK3R2	ENSG00000268173	-0.8332645489403778	[513,413]	[202,48]	-6	hSpCas9	negative selection	311889
18166281	18166304	19	+	26472758	KBM7	viability	GCAACGAGAAAGAGATGCAAAGG	PIK3R2	ENSG00000268173	-0.11894316751016776	[242,256]	[116,101]	-1	hSpCas9	negative selection	311890
18168789	18168812	19	+	26472758	KBM7	viability	GGGCAAGATCAACCGCACGCAGG	PIK3R2	ENSG00000268173	0.6159648688131751	[96,85]	[96,37]	6	hSpCas9	negative selection	311891
18155878	18155901	19	-	26472758	KBM7	viability	GAAGCCCTCAGGGCCCGCCATGG	PIK3R2	ENSG00000268173	1.2161863758620737	[465,199]	[403,302]	9	hSpCas9	negative selection	311892
18155966	18155989	19	+	26472758	KBM7	viability	CGTGCTGGTAGTGAGCCGGGCGG	PIK3R2	ENSG00000268173	-0.10460500250909321	[181,180]	[46,108]	-1	hSpCas9	negative selection	311893
18156089	18156112	19	-	26472758	KBM7	viability	GGAACTCCACATAGGTGCCAGGG	PIK3R2	ENSG00000268173	0.24302623134749318	[613,579]	[363,304]	2	hSpCas9	negative selection	311894
18160481	18160504	19	-	26472758	KBM7	viability	AGAACTGCTCGGGCAAGTCGGGG	PIK3R2	ENSG00000268173	0.4029234435718334	[527,446]	[245,351]	4	hSpCas9	negative selection	311895
18156021	18156044	19	+	26472758	Raji	viability	GAGCGCTGCCCACAGAGCGTGGG	PIK3R2	ENSG00000268173	0.009772738747177323	[106]	[24]	0	hSpCas9	negative selection	503004
18162411	18162434	19	+	26472758	Raji	viability	GGAGGTGAACGAGAAACTCCGGG	PIK3R2	ENSG00000268173	1.4635273455988747	[49]	[31]	9	hSpCas9	negative selection	503005
18162017	18162040	19	+	26472758	Raji	viability	GGAACACTTGGAAGAGCAGGAGG	PIK3R2	ENSG00000268173	-0.8694090734650753	[369]	[46]	-6	hSpCas9	negative selection	503006
18163277	18163300	19	+	26472758	Raji	viability	GGAGGACAGCGTGGAGGCAGTGG	PIK3R2	ENSG00000268173	-2.1063957556581405	[166]	[8]	-8	hSpCas9	negative selection	503007
18166281	18166304	19	+	26472758	Raji	viability	GCAACGAGAAAGAGATGCAAAGG	PIK3R2	ENSG00000268173	-0.9615115458374683	[192]	[22]	-6	hSpCas9	negative selection	503008
18168789	18168812	19	+	26472758	Raji	viability	GGGCAAGATCAACCGCACGCAGG	PIK3R2	ENSG00000268173	0.16396706373996706	[49]	[12]	1	hSpCas9	negative selection	503009
18155878	18155901	19	-	26472758	Raji	viability	GAAGCCCTCAGGGCCCGCCATGG	PIK3R2	ENSG00000268173	-0.3207101167306908	[295]	[54]	-3	hSpCas9	negative selection	503010
18155966	18155989	19	+	26472758	Raji	viability	CGTGCTGGTAGTGAGCCGGGCGG	PIK3R2	ENSG00000268173	-0.07848300993773427	[90]	[19]	0	hSpCas9	negative selection	503011
18156089	18156112	19	-	26472758	Raji	viability	GGAACTCCACATAGGTGCCAGGG	PIK3R2	ENSG00000268173	-0.8672311462064867	[337]	[42]	-6	hSpCas9	negative selection	503012
18160481	18160504	19	-	26472758	Raji	viability	AGAACTGCTCGGGCAAGTCGGGG	PIK3R2	ENSG00000268173	0.2943149621216017	[252]	[71]	2	hSpCas9	negative selection	503013
18156021	18156044	19	+	26472758	K562	viability	GAGCGCTGCCCACAGAGCGTGGG	PIK3R2	ENSG00000268173	-0.6565014986255505	[210]	[112]	-4	hSpCas9	negative selection	694122
18162411	18162434	19	+	26472758	K562	viability	GGAGGTGAACGAGAAACTCCGGG	PIK3R2	ENSG00000268173	0.36471296138415843	[68]	[74]	3	hSpCas9	negative selection	694123
18162017	18162040	19	+	26472758	K562	viability	GGAACACTTGGAAGAGCAGGAGG	PIK3R2	ENSG00000268173	-0.4225126198409904	[515]	[324]	-3	hSpCas9	negative selection	694124
18163277	18163300	19	+	26472758	K562	viability	GGAGGACAGCGTGGAGGCAGTGG	PIK3R2	ENSG00000268173	-8.629025384848928	[468]	[0]	-9	hSpCas9	negative selection	694125
18166281	18166304	19	+	26472758	K562	viability	GCAACGAGAAAGAGATGCAAAGG	PIK3R2	ENSG00000268173	-0.9435142229266281	[261]	[114]	-5	hSpCas9	negative selection	694126
18168789	18168812	19	+	26472758	K562	viability	GGGCAAGATCAACCGCACGCAGG	PIK3R2	ENSG00000268173	0.9163645299822432	[58]	[93]	7	hSpCas9	negative selection	694127
18155878	18155901	19	-	26472758	K562	viability	GAAGCCCTCAGGGCCCGCCATGG	PIK3R2	ENSG00000268173	0.2775855916016463	[214]	[219]	2	hSpCas9	negative selection	694128
18155966	18155989	19	+	26472758	K562	viability	CGTGCTGGTAGTGAGCCGGGCGG	PIK3R2	ENSG00000268173	0.5048084122446768	[90]	[108]	4	hSpCas9	negative selection	694129
18156089	18156112	19	-	26472758	K562	viability	GGAACTCCACATAGGTGCCAGGG	PIK3R2	ENSG00000268173	-0.29137093107300716	[547]	[377]	-2	hSpCas9	negative selection	694130
18160481	18160504	19	-	26472758	K562	viability	AGAACTGCTCGGGCAAGTCGGGG	PIK3R2	ENSG00000268173	0.7345220420461619	[439]	[617]	6	hSpCas9	negative selection	694131
18155908	18155931	19	+	26627737	DLD1	viability	GCGCTCTGTACCCGTTCCGCCGG	PIK3R2	ENSG00000268173	-1.9858328699240488	[672]	[89,39,31]	-8	hSpCas9	negative selection	803363
18160521	18160544	19	-	26627737	DLD1	viability	ACAAGCTTCACCAGAAGAGGGGG	PIK3R2	ENSG00000268173	-0.5868592206347841	[246]	[58,20,69]	-5	hSpCas9	negative selection	803364
18160915	18160938	19	-	26627737	DLD1	viability	TGAGATTCGCTGTCCAGCCCTGG	PIK3R2	ENSG00000268173	-0.94097272178072	[998]	[100,291,108]	-7	hSpCas9	negative selection	803365
18161052	18161075	19	+	26627737	DLD1	viability	AGACTGGTCCCTGAGCGACGTGG	PIK3R2	ENSG00000268173	-0.24808537197204905	[1118]	[420,227,239]	-3	hSpCas9	negative selection	803366
18161267	18161290	19	+	26627737	DLD1	viability	ATCTGTCCGCAGAGGCCGCGGGG	PIK3R2	ENSG00000268173	-0.797352585952392	[561]	[80,120,101]	-6	hSpCas9	negative selection	803367
18162014	18162037	19	+	26627737	DLD1	viability	TCAGGAACACTTGGAAGAGCAGG	PIK3R2	ENSG00000268173	0.33400710642215214	[421]	[185,87,213]	3	hSpCas9	negative selection	803368
18155908	18155931	19	+	26627737	GBM cells	viability after 5 days	GCGCTCTGTACCCGTTCCGCCGG	PIK3R2	ENSG00000268173	0.10438299318566518	[195]	[111,113]	1	hSpCas9	negative selection	885678
18160521	18160544	19	-	26627737	GBM cells	viability after 5 days	ACAAGCTTCACCAGAAGAGGGGG	PIK3R2	ENSG00000268173	-0.19419552950579574	[239]	[86,137]	-3	hSpCas9	negative selection	885679
18160915	18160938	19	-	26627737	GBM cells	viability after 5 days	TGAGATTCGCTGTCCAGCCCTGG	PIK3R2	ENSG00000268173	-0.7663907341530742	[359]	[104,121]	-8	hSpCas9	negative selection	885680
18161052	18161075	19	+	26627737	GBM cells	viability after 5 days	AGACTGGTCCCTGAGCGACGTGG	PIK3R2	ENSG00000268173	-0.12899212168419905	[521]	[242,268]	-2	hSpCas9	negative selection	885681
18161267	18161290	19	+	26627737	GBM cells	viability after 5 days	ATCTGTCCGCAGAGGCCGCGGGG	PIK3R2	ENSG00000268173	-0.16557485156602803	[182]	[72,101]	-3	hSpCas9	negative selection	885682
18162014	18162037	19	+	26627737	GBM cells	viability after 5 days	TCAGGAACACTTGGAAGAGCAGG	PIK3R2	ENSG00000268173	0.31395137416452923	[287]	[181,201]	5	hSpCas9	negative selection	885683
18155908	18155931	19	+	26627737	GBM cells	viability after 13 days	GCGCTCTGTACCCGTTCCGCCGG	PIK3R2	ENSG00000268173	-0.9591765794482774	[195]	[73,38]	-8	hSpCas9	negative selection	967993
18160521	18160544	19	-	26627737	GBM cells	viability after 13 days	ACAAGCTTCACCAGAAGAGGGGG	PIK3R2	ENSG00000268173	-0.1546947794185084	[239]	[68,155]	-2	hSpCas9	negative selection	967994
18160915	18160938	19	-	26627737	GBM cells	viability after 13 days	TGAGATTCGCTGTCCAGCCCTGG	PIK3R2	ENSG00000268173	-0.9611280398400639	[359]	[69,124]	-8	hSpCas9	negative selection	967995
18161052	18161075	19	+	26627737	GBM cells	viability after 13 days	AGACTGGTCCCTGAGCGACGTGG	PIK3R2	ENSG00000268173	-0.15770300050102748	[521]	[329,191]	-2	hSpCas9	negative selection	967996
18161267	18161290	19	+	26627737	GBM cells	viability after 13 days	ATCTGTCCGCAGAGGCCGCGGGG	PIK3R2	ENSG00000268173	-0.04157945645048833	[182]	[69,117]	0	hSpCas9	negative selection	967997
18162014	18162037	19	+	26627737	GBM cells	viability after 13 days	TCAGGAACACTTGGAAGAGCAGG	PIK3R2	ENSG00000268173	-0.051104172495463396	[287]	[141,157]	0	hSpCas9	negative selection	967998
18155908	18155931	19	+	26627737	GBM cells	viability after 21 days	GCGCTCTGTACCCGTTCCGCCGG	PIK3R2	ENSG00000268173	-0.5962900881731277	[195]	[71,68]	-5	hSpCas9	negative selection	1050308
18160521	18160544	19	-	26627737	GBM cells	viability after 21 days	ACAAGCTTCACCAGAAGAGGGGG	PIK3R2	ENSG00000268173	0.47725675855526656	[239]	[192,170]	5	hSpCas9	negative selection	1050309
18160915	18160938	19	-	26627737	GBM cells	viability after 21 days	TGAGATTCGCTGTCCAGCCCTGG	PIK3R2	ENSG00000268173	-0.25641554695235536	[359]	[169,157]	-2	hSpCas9	negative selection	1050310
18161052	18161075	19	+	26627737	GBM cells	viability after 21 days	AGACTGGTCCCTGAGCGACGTGG	PIK3R2	ENSG00000268173	-0.615338419288827	[521]	[193,176]	-5	hSpCas9	negative selection	1050311
18161267	18161290	19	+	26627737	GBM cells	viability after 21 days	ATCTGTCCGCAGAGGCCGCGGGG	PIK3R2	ENSG00000268173	0.7000230692360572	[182]	[172,150]	7	hSpCas9	negative selection	1050312
18162014	18162037	19	+	26627737	GBM cells	viability after 21 days	TCAGGAACACTTGGAAGAGCAGG	PIK3R2	ENSG00000268173	-0.12467307254234795	[287]	[154,132]	-1	hSpCas9	negative selection	1050313
18155908	18155931	19	+	26627737	RPE1	viability after 9 days	GCGCTCTGTACCCGTTCCGCCGG	PIK3R2	ENSG00000268173	-0.7912323666831176	[571]	[92,116]	-5	hSpCas9	negative selection	1132623
18160521	18160544	19	-	26627737	RPE1	viability after 9 days	ACAAGCTTCACCAGAAGAGGGGG	PIK3R2	ENSG00000268173	-0.15849297777130733	[436]	[36,232]	-1	hSpCas9	negative selection	1132624
18160915	18160938	19	-	26627737	RPE1	viability after 9 days	TGAGATTCGCTGTCCAGCCCTGG	PIK3R2	ENSG00000268173	-2.287153847218963	[1831]	[151,72]	-9	hSpCas9	negative selection	1132625
18161052	18161075	19	+	26627737	RPE1	viability after 9 days	AGACTGGTCCCTGAGCGACGTGG	PIK3R2	ENSG00000268173	0.03619350485262629	[1460]	[382,579]	0	hSpCas9	negative selection	1132626
18161267	18161290	19	+	26627737	RPE1	viability after 9 days	ATCTGTCCGCAGAGGCCGCGGGG	PIK3R2	ENSG00000268173	0.7105747537184217	[519]	[251,284]	5	hSpCas9	negative selection	1132627
18162014	18162037	19	+	26627737	RPE1	viability after 9 days	TCAGGAACACTTGGAAGAGCAGG	PIK3R2	ENSG00000268173	0.4490268962293299	[831]	[300,425]	3	hSpCas9	negative selection	1132628
18155908	18155931	19	+	26627737	RPE1	viability after 12 days	GCGCTCTGTACCCGTTCCGCCGG	PIK3R2	ENSG00000268173	-0.5957867245404327	[571]	[90,112]	-4	hSpCas9	negative selection	1214938
18160521	18160544	19	-	26627737	RPE1	viability after 12 days	ACAAGCTTCACCAGAAGAGGGGG	PIK3R2	ENSG00000268173	-0.6771084306911868	[436]	[70,75]	-5	hSpCas9	negative selection	1214939
18160915	18160938	19	-	26627737	RPE1	viability after 12 days	TGAGATTCGCTGTCCAGCCCTGG	PIK3R2	ENSG00000268173	-1.328592853038016	[1831]	[211,178]	-7	hSpCas9	negative selection	1214940
18161052	18161075	19	+	26627737	RPE1	viability after 12 days	AGACTGGTCCCTGAGCGACGTGG	PIK3R2	ENSG00000268173	0.14918981149852117	[1460]	[342,532]	1	hSpCas9	negative selection	1214941
18161267	18161290	19	+	26627737	RPE1	viability after 12 days	ATCTGTCCGCAGAGGCCGCGGGG	PIK3R2	ENSG00000268173	0.8174305502417782	[519]	[269,220]	5	hSpCas9	negative selection	1214942
18162014	18162037	19	+	26627737	RPE1	viability after 12 days	TCAGGAACACTTGGAAGAGCAGG	PIK3R2	ENSG00000268173	0.38507269854860404	[831]	[169,420]	2	hSpCas9	negative selection	1214943
18155908	18155931	19	+	26627737	RPE1	viability after 15 days	GCGCTCTGTACCCGTTCCGCCGG	PIK3R2	ENSG00000268173	-1.1631741922371142	[571]	[29,112]	-6	hSpCas9	negative selection	1297253
18160521	18160544	19	-	26627737	RPE1	viability after 15 days	ACAAGCTTCACCAGAAGAGGGGG	PIK3R2	ENSG00000268173	-0.532651795347808	[436]	[87,82]	-3	hSpCas9	negative selection	1297254
18160915	18160938	19	-	26627737	RPE1	viability after 15 days	TGAGATTCGCTGTCCAGCCCTGG	PIK3R2	ENSG00000268173	-1.2390209432559447	[1831]	[328,113]	-6	hSpCas9	negative selection	1297255
18161052	18161075	19	+	26627737	RPE1	viability after 15 days	AGACTGGTCCCTGAGCGACGTGG	PIK3R2	ENSG00000268173	0.45826699477859967	[1460]	[437,692]	3	hSpCas9	negative selection	1297256
18161267	18161290	19	+	26627737	RPE1	viability after 15 days	ATCTGTCCGCAGAGGCCGCGGGG	PIK3R2	ENSG00000268173	1.2892199419330845	[519]	[443,277]	7	hSpCas9	negative selection	1297257
18162014	18162037	19	+	26627737	RPE1	viability after 15 days	TCAGGAACACTTGGAAGAGCAGG	PIK3R2	ENSG00000268173	0.4746456210661404	[831]	[183,464]	3	hSpCas9	negative selection	1297258
18155908	18155931	19	+	26627737	RPE1	viability after 18 days	GCGCTCTGTACCCGTTCCGCCGG	PIK3R2	ENSG00000268173	-1.360807603879255	[571]	[33,87]	-7	hSpCas9	negative selection	1379568
18160521	18160544	19	-	26627737	RPE1	viability after 18 days	ACAAGCTTCACCAGAAGAGGGGG	PIK3R2	ENSG00000268173	-0.8873873345804582	[436]	[41,86]	-5	hSpCas9	negative selection	1379569
18160915	18160938	19	-	26627737	RPE1	viability after 18 days	TGAGATTCGCTGTCCAGCCCTGG	PIK3R2	ENSG00000268173	-1.1642341494900472	[1831]	[310,123]	-6	hSpCas9	negative selection	1379570
18161052	18161075	19	+	26627737	RPE1	viability after 18 days	AGACTGGTCCCTGAGCGACGTGG	PIK3R2	ENSG00000268173	0.11146085369144398	[1460]	[336,520]	0	hSpCas9	negative selection	1379571
18161267	18161290	19	+	26627737	RPE1	viability after 18 days	ATCTGTCCGCAGAGGCCGCGGGG	PIK3R2	ENSG00000268173	0.38825886397464887	[519]	[173,193]	2	hSpCas9	negative selection	1379572
18162014	18162037	19	+	26627737	RPE1	viability after 18 days	TCAGGAACACTTGGAAGAGCAGG	PIK3R2	ENSG00000268173	0.10933441069856994	[831]	[189,297]	0	hSpCas9	negative selection	1379573
18155908	18155931	19	+	26627737	HeLa	viability after 8 days	GCGCTCTGTACCCGTTCCGCCGG	PIK3R2	ENSG00000268173	-0.5967164080032331	[387]	[130,78,127]	-5	hSpCas9	negative selection	1461883
18160521	18160544	19	-	26627737	HeLa	viability after 8 days	ACAAGCTTCACCAGAAGAGGGGG	PIK3R2	ENSG00000268173	-0.26753868077750037	[384]	[196,134,100]	-3	hSpCas9	negative selection	1461884
18160915	18160938	19	-	26627737	HeLa	viability after 8 days	TGAGATTCGCTGTCCAGCCCTGG	PIK3R2	ENSG00000268173	0.4077477697515086	[509]	[456,315,155]	4	hSpCas9	negative selection	1461885
18161052	18161075	19	+	26627737	HeLa	viability after 8 days	AGACTGGTCCCTGAGCGACGTGG	PIK3R2	ENSG00000268173	-0.3883911594454792	[1060]	[482,327,280]	-4	hSpCas9	negative selection	1461886
18161267	18161290	19	+	26627737	HeLa	viability after 8 days	ATCTGTCCGCAGAGGCCGCGGGG	PIK3R2	ENSG00000268173	-0.9219043853530173	[368]	[140,1,120]	-7	hSpCas9	negative selection	1461887
18162014	18162037	19	+	26627737	HeLa	viability after 8 days	TCAGGAACACTTGGAAGAGCAGG	PIK3R2	ENSG00000268173	-0.731484486155393	[736]	[174,170,226]	-6	hSpCas9	negative selection	1461888
18155908	18155931	19	+	26627737	HeLa	viability after 12 days	GCGCTCTGTACCCGTTCCGCCGG	PIK3R2	ENSG00000268173	0.49246292353077403	[387]	[252,192,234]	4	hSpCas9	negative selection	1544198
18160521	18160544	19	-	26627737	HeLa	viability after 12 days	ACAAGCTTCACCAGAAGAGGGGG	PIK3R2	ENSG00000268173	-0.7007895304390946	[384]	[76,88,127]	-6	hSpCas9	negative selection	1544199
18160915	18160938	19	-	26627737	HeLa	viability after 12 days	TGAGATTCGCTGTCCAGCCCTGG	PIK3R2	ENSG00000268173	0.5262283130563022	[509]	[284,256,372]	4	hSpCas9	negative selection	1544200
18161052	18161075	19	+	26627737	HeLa	viability after 12 days	AGACTGGTCCCTGAGCGACGTGG	PIK3R2	ENSG00000268173	-0.14588210925064593	[1060]	[498,300,401]	-1	hSpCas9	negative selection	1544201
18161267	18161290	19	+	26627737	HeLa	viability after 12 days	ATCTGTCCGCAGAGGCCGCGGGG	PIK3R2	ENSG00000268173	-0.26465878129187126	[368]	[66,136,173]	-2	hSpCas9	negative selection	1544202
18162014	18162037	19	+	26627737	HeLa	viability after 12 days	TCAGGAACACTTGGAAGAGCAGG	PIK3R2	ENSG00000268173	-0.153752383379413	[736]	[278,221,325]	-1	hSpCas9	negative selection	1544203
18155908	18155931	19	+	26627737	HeLa	viability after 15 days	GCGCTCTGTACCCGTTCCGCCGG	PIK3R2	ENSG00000268173	-0.013106242533101678	[387]	[188,185,88]	0	hSpCas9	negative selection	1626513
18160521	18160544	19	-	26627737	HeLa	viability after 15 days	ACAAGCTTCACCAGAAGAGGGGG	PIK3R2	ENSG00000268173	-1.6610189278928797	[384]	[56,24,67]	-8	hSpCas9	negative selection	1626514
18160915	18160938	19	-	26627737	HeLa	viability after 15 days	TGAGATTCGCTGTCCAGCCCTGG	PIK3R2	ENSG00000268173	-0.26865001752909945	[509]	[94,226,197]	-2	hSpCas9	negative selection	1626515
18161052	18161075	19	+	26627737	HeLa	viability after 15 days	AGACTGGTCCCTGAGCGACGTGG	PIK3R2	ENSG00000268173	-0.1804209553975218	[1060]	[515,168,462]	-1	hSpCas9	negative selection	1626516
18161267	18161290	19	+	26627737	HeLa	viability after 15 days	ATCTGTCCGCAGAGGCCGCGGGG	PIK3R2	ENSG00000268173	-0.322255905053321	[368]	[14,175,174]	-3	hSpCas9	negative selection	1626517
18162014	18162037	19	+	26627737	HeLa	viability after 15 days	TCAGGAACACTTGGAAGAGCAGG	PIK3R2	ENSG00000268173	-0.6879595332950805	[736]	[218,204,129]	-6	hSpCas9	negative selection	1626518
18155908	18155931	19	+	26627737	HeLa	viability after 18 days	GCGCTCTGTACCCGTTCCGCCGG	PIK3R2	ENSG00000268173	0.02789391186891219	[387]	[129,160,88]	0	hSpCas9	negative selection	1708828
18160521	18160544	19	-	26627737	HeLa	viability after 18 days	ACAAGCTTCACCAGAAGAGGGGG	PIK3R2	ENSG00000268173	-1.6197968194886228	[384]	[39,21,67]	-8	hSpCas9	negative selection	1708829
18160915	18160938	19	-	26627737	HeLa	viability after 18 days	TGAGATTCGCTGTCCAGCCCTGG	PIK3R2	ENSG00000268173	-0.23677764259222417	[509]	[67,191,197]	-2	hSpCas9	negative selection	1708830
18161052	18161075	19	+	26627737	HeLa	viability after 18 days	AGACTGGTCCCTGAGCGACGTGG	PIK3R2	ENSG00000268173	-0.1795813629180496	[1060]	[340,146,462]	-1	hSpCas9	negative selection	1708831
18161267	18161290	19	+	26627737	HeLa	viability after 18 days	ATCTGTCCGCAGAGGCCGCGGGG	PIK3R2	ENSG00000268173	-0.3312378099541338	[368]	[9,143,174]	-3	hSpCas9	negative selection	1708832
18162014	18162037	19	+	26627737	HeLa	viability after 18 days	TCAGGAACACTTGGAAGAGCAGG	PIK3R2	ENSG00000268173	-0.6663704478142393	[736]	[148,173,129]	-5	hSpCas9	negative selection	1708833
18155908	18155931	19	+	26627737	HCT116	viability after 6 days	GCGCTCTGTACCCGTTCCGCCGG	PIK3R2	ENSG00000268173	0.7276491195531987	[588]	[298,72]	4	hSpCas9	negative selection	1791143
18160521	18160544	19	-	26627737	HCT116	viability after 6 days	ACAAGCTTCACCAGAAGAGGGGG	PIK3R2	ENSG00000268173	0.21015300509173102	[410]	[144,35]	1	hSpCas9	negative selection	1791144
18160915	18160938	19	-	26627737	HCT116	viability after 6 days	TGAGATTCGCTGTCCAGCCCTGG	PIK3R2	ENSG00000268173	-1.2682885324152493	[1016]	[86,54]	-6	hSpCas9	negative selection	1791145
18161052	18161075	19	+	26627737	HCT116	viability after 6 days	AGACTGGTCCCTGAGCGACGTGG	PIK3R2	ENSG00000268173	-0.7507488239570603	[1052]	[225,27]	-4	hSpCas9	negative selection	1791146
18161267	18161290	19	+	26627737	HCT116	viability after 6 days	ATCTGTCCGCAGAGGCCGCGGGG	PIK3R2	ENSG00000268173	-0.0796292498066466	[646]	[54,118]	0	hSpCas9	negative selection	1791147
18162014	18162037	19	+	26627737	HCT116	viability after 6 days	TCAGGAACACTTGGAAGAGCAGG	PIK3R2	ENSG00000268173	1.6137464901585687	[768]	[592,246]	8	hSpCas9	negative selection	1791148
18155908	18155931	19	+	26627737	HCT116	viability after 8 days	GCGCTCTGTACCCGTTCCGCCGG	PIK3R2	ENSG00000268173	-0.06445422200393153	[235]	[110,67,192]	0	hSpCas9	negative selection	1873458
18160521	18160544	19	-	26627737	HCT116	viability after 8 days	ACAAGCTTCACCAGAAGAGGGGG	PIK3R2	ENSG00000268173	0.32729491604623884	[193]	[116,145,138]	3	hSpCas9	negative selection	1873459
18160915	18160938	19	-	26627737	HCT116	viability after 8 days	TGAGATTCGCTGTCCAGCCCTGG	PIK3R2	ENSG00000268173	-0.20617377568885742	[569]	[333,303,180]	-2	hSpCas9	negative selection	1873460
18161052	18161075	19	+	26627737	HCT116	viability after 8 days	AGACTGGTCCCTGAGCGACGTGG	PIK3R2	ENSG00000268173	-0.39396800903917517	[507]	[295,166,177]	-5	hSpCas9	negative selection	1873461
18161267	18161290	19	+	26627737	HCT116	viability after 8 days	ATCTGTCCGCAGAGGCCGCGGGG	PIK3R2	ENSG00000268173	0.015511231486060817	[194]	[124,81,118]	0	hSpCas9	negative selection	1873462
18162014	18162037	19	+	26627737	HCT116	viability after 8 days	TCAGGAACACTTGGAAGAGCAGG	PIK3R2	ENSG00000268173	0.6547474991644151	[302]	[334,286,168]	6	hSpCas9	negative selection	1873463
18155908	18155931	19	+	26627737	HCT116	viability after 9 days	GCGCTCTGTACCCGTTCCGCCGG	PIK3R2	ENSG00000268173	-0.055204527086351325	[588]	[309,25]	0	hSpCas9	negative selection	1955773
18160521	18160544	19	-	26627737	HCT116	viability after 9 days	ACAAGCTTCACCAGAAGAGGGGG	PIK3R2	ENSG00000268173	-1.9182321656187753	[410]	[42,17]	-8	hSpCas9	negative selection	1955774
18160915	18160938	19	-	26627737	HCT116	viability after 9 days	TGAGATTCGCTGTCCAGCCCTGG	PIK3R2	ENSG00000268173	-0.13690479092453256	[1016]	[127,340]	-1	hSpCas9	negative selection	1955775
18161052	18161075	19	+	26627737	HCT116	viability after 9 days	AGACTGGTCCCTGAGCGACGTGG	PIK3R2	ENSG00000268173	0.42697689840527686	[1052]	[582,215]	3	hSpCas9	negative selection	1955776
18161267	18161290	19	+	26627737	HCT116	viability after 9 days	ATCTGTCCGCAGAGGCCGCGGGG	PIK3R2	ENSG00000268173	-0.7324423413179239	[646]	[189,35]	-5	hSpCas9	negative selection	1955777
18162014	18162037	19	+	26627737	HCT116	viability after 9 days	TCAGGAACACTTGGAAGAGCAGG	PIK3R2	ENSG00000268173	0.1051112982145837	[768]	[288,166]	0	hSpCas9	negative selection	1955778
18155908	18155931	19	+	26627737	HCT116	viability after 12 days	GCGCTCTGTACCCGTTCCGCCGG	PIK3R2	ENSG00000268173	0.4965426192477996	[235]	[201,151,167]	5	hSpCas9	negative selection	2038088
18160521	18160544	19	-	26627737	HCT116	viability after 12 days	ACAAGCTTCACCAGAAGAGGGGG	PIK3R2	ENSG00000268173	-0.31753715434125174	[193]	[65,47,131]	-3	hSpCas9	negative selection	2038089
18160915	18160938	19	-	26627737	HCT116	viability after 12 days	TGAGATTCGCTGTCCAGCCCTGG	PIK3R2	ENSG00000268173	-0.7583351114094055	[569]	[148,146,236]	-7	hSpCas9	negative selection	2038090
18161052	18161075	19	+	26627737	HCT116	viability after 12 days	AGACTGGTCCCTGAGCGACGTGG	PIK3R2	ENSG00000268173	0.44757185441789993	[507]	[310,244,537]	4	hSpCas9	negative selection	2038091
18161267	18161290	19	+	26627737	HCT116	viability after 12 days	ATCTGTCCGCAGAGGCCGCGGGG	PIK3R2	ENSG00000268173	0.4923732472659337	[194]	[150,148,131]	5	hSpCas9	negative selection	2038092
18162014	18162037	19	+	26627737	HCT116	viability after 12 days	TCAGGAACACTTGGAAGAGCAGG	PIK3R2	ENSG00000268173	0.7388356645354613	[302]	[257,352,188]	6	hSpCas9	negative selection	2038093
18155908	18155931	19	+	26627737	HCT116	viability after 15 days	GCGCTCTGTACCCGTTCCGCCGG	PIK3R2	ENSG00000268173	0.3780645724342002	[235]	[220,229,83]	3	hSpCas9	negative selection	2120403
18160521	18160544	19	-	26627737	HCT116	viability after 15 days	ACAAGCTTCACCAGAAGAGGGGG	PIK3R2	ENSG00000268173	0.7430989171915721	[193]	[171,59,323]	6	hSpCas9	negative selection	2120404
18160915	18160938	19	-	26627737	HCT116	viability after 15 days	TGAGATTCGCTGTCCAGCCCTGG	PIK3R2	ENSG00000268173	-0.8751123947127966	[569]	[239,131,170]	-7	hSpCas9	negative selection	2120405
18161052	18161075	19	+	26627737	HCT116	viability after 15 days	AGACTGGTCCCTGAGCGACGTGG	PIK3R2	ENSG00000268173	-0.06515324974622705	[507]	[500,115,246]	0	hSpCas9	negative selection	2120406
18161267	18161290	19	+	26627737	HCT116	viability after 15 days	ATCTGTCCGCAGAGGCCGCGGGG	PIK3R2	ENSG00000268173	-0.5519865060100998	[194]	[128,66,39]	-5	hSpCas9	negative selection	2120407
18162014	18162037	19	+	26627737	HCT116	viability after 15 days	TCAGGAACACTTGGAAGAGCAGG	PIK3R2	ENSG00000268173	0.8031318813455759	[302]	[361,252,302]	7	hSpCas9	negative selection	2120408
18155908	18155931	19	+	26627737	HCT116	viability after 18 days	GCGCTCTGTACCCGTTCCGCCGG	PIK3R2	ENSG00000268173	-0.29547698979499853	[235]	[74,107,94]	-3	hSpCas9	negative selection	2202718
18160521	18160544	19	-	26627737	HCT116	viability after 18 days	ACAAGCTTCACCAGAAGAGGGGG	PIK3R2	ENSG00000268173	0.3265262978410639	[193]	[104,69,183]	3	hSpCas9	negative selection	2202719
18160915	18160938	19	-	26627737	HCT116	viability after 18 days	TGAGATTCGCTGTCCAGCCCTGG	PIK3R2	ENSG00000268173	-0.5711972109596151	[569]	[195,218,136]	-5	hSpCas9	negative selection	2202720
18161052	18161075	19	+	26627737	HCT116	viability after 18 days	AGACTGGTCCCTGAGCGACGTGG	PIK3R2	ENSG00000268173	0.3744184419267027	[507]	[397,140,432]	3	hSpCas9	negative selection	2202721
18161267	18161290	19	+	26627737	HCT116	viability after 18 days	ATCTGTCCGCAGAGGCCGCGGGG	PIK3R2	ENSG00000268173	-0.3414085830977365	[194]	[88,95,34]	-3	hSpCas9	negative selection	2202722
18162014	18162037	19	+	26627737	HCT116	viability after 18 days	TCAGGAACACTTGGAAGAGCAGG	PIK3R2	ENSG00000268173	0.04928533853237488	[302]	[94,240,110]	0	hSpCas9	negative selection	2202723
18155082	18155105	19	-	25494202	A375	resistance to PLX-4720 (puromycin)	GCCTCAGCCTCCCGAGTAGCAGG	PIK3R2	ENSG00000268173	0.5805591546882161	[16,8]	[5,1]	2	dCas9-VP64	positive selection	2421438
18171323	18171346	19	+	25494202	A375	resistance to PLX-4720 (puromycin)	CACCTGTAATTCCAGCACTTGGG	PIK3R2	ENSG00000268173	1.9829372138366936	[192,253]	[363,12]	7	dCas9-VP64	positive selection	2430094
18155082	18155105	19	-	25494202	A375	resistance to PLX-4720 (zeocin)	GCCTCAGCCTCCCGAGTAGCAGG	PIK3R2	ENSG00000268173	0.21208715000527545	[37,95]	[24,24]	1	dCas9-VP64	positive selection	2516693
18171323	18171346	19	+	25494202	A375	resistance to PLX-4720 (zeocin)	CACCTGTAATTCCAGCACTTGGG	PIK3R2	ENSG00000268173	2.0349420860207257	[143,154]	[35,352]	8	dCas9-VP64	positive selection	2525349
18160927	18160950	19	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CAGCGAATCTCACTACCGCCCGG	PIK3R2	ENSG00000268173	0.22833707272482484	[3,2]	[2,3]	5	hSpCas9	positive selection	3011391
18155967	18155990	19	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CGTGCTGGTAGTGAGCCGGGCGG	PIK3R2	ENSG00000268173	-1.2229408799458348	[2,2]	[0,0]	-9	hSpCas9	positive selection	3011392
18156089	18156112	19	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GGAACTCCACATAGGTGCCAGGG	PIK3R2	ENSG00000268173	-0.19444277090596196	[3,3]	[3,1]	-3	hSpCas9	positive selection	3011393
18162271	18162294	19	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GTACCACTCAGCATCCTGCAGGG	PIK3R2	ENSG00000268173	-0.0217648391086388	[3,4]	[3,2]	0	hSpCas9	positive selection	3011394
18160927	18160950	19	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CAGCGAATCTCACTACCGCCCGG	PIK3R2	ENSG00000268173	-0.47307492674408236	[3,3]	[2,0]	-6	hSpCas9	positive selection	3079249
18155967	18155990	19	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CGTGCTGGTAGTGAGCCGGGCGG	PIK3R2	ENSG00000268173	0.7661268129468948	[2,2]	[1,3]	9	hSpCas9	positive selection	3079250
18156089	18156112	19	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GGAACTCCACATAGGTGCCAGGG	PIK3R2	ENSG00000268173	-0.3928174904786695	[3,3]	[2,0]	-6	hSpCas9	positive selection	3079251
18162271	18162294	19	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GTACCACTCAGCATCCTGCAGGG	PIK3R2	ENSG00000268173	-0.04706386614501387	[3,3]	[4,1]	0	hSpCas9	positive selection	3079252
18155900	18155923		-	24336571	A375	resistance to PLX after 7 days	ACGGGTACAGAGCGCGGTACTGG	PIK3R2	ENSG00000268173	-0.1625516441433723	[18,19]	[15,18]	-5	hSpCas9	positive selection	3135654
18160523	18160546		+	24336571	A375	resistance to PLX after 7 days	CCCTCTTCTGGTGAAGCTTGTGG	PIK3R2	ENSG00000268173	-0.04785038121207119	[18,14]	[16,15]	-1	hSpCas9	positive selection	3135655
18160496	18160519		+	24336571	A375	resistance to PLX after 7 days	GCAGTTCTCCCCACCTGATGTGG	PIK3R2	ENSG00000268173	0.16554608516720792	[8,9]	[8,11]	5	hSpCas9	positive selection	3135656
18155908	18155931		+	24336571	A375	resistance to PLX after 7 days	GCGCTCTGTACCCGTTCCGCCGG	PIK3R2	ENSG00000268173	-0.4137656049117172	[15,15]	[10,11]	-9	hSpCas9	positive selection	3135657
18155900	18155923		-	24336571	A375	resistance to PLX after 14 days	ACGGGTACAGAGCGCGGTACTGG	PIK3R2	ENSG00000268173	-0.8822224219170036	[15,22]	[5,3]	-9	hSpCas9	positive selection	3193447
18160523	18160546		+	24336571	A375	resistance to PLX after 14 days	CCCTCTTCTGGTGAAGCTTGTGG	PIK3R2	ENSG00000268173	0.06805713473037195	[15,15]	[6,7]	0	hSpCas9	positive selection	3193448
18160496	18160519		+	24336571	A375	resistance to PLX after 14 days	GCAGTTCTCCCCACCTGATGTGG	PIK3R2	ENSG00000268173	-0.38589218645113554	[8,10]	[2,3]	-4	hSpCas9	positive selection	3193449
18155908	18155931		+	24336571	A375	resistance to PLX after 14 days	GCGCTCTGTACCCGTTCCGCCGG	PIK3R2	ENSG00000268173	-0.7474760437978017	[12,11]	[2,2]	-8	hSpCas9	positive selection	3193450
18155900	18155923		-	24336571	A375	viability after 7 days	ACGGGTACAGAGCGCGGTACTGG	PIK3R2	ENSG00000268173	0.14892280608195219	[18]	[18,19]	2	hSpCas9	negative selection	3251240
18160523	18160546		+	24336571	A375	viability after 7 days	CCCTCTTCTGGTGAAGCTTGTGG	PIK3R2	ENSG00000268173	0.3243876787039701	[13]	[18,14]	5	hSpCas9	negative selection	3251241
18160496	18160519		+	24336571	A375	viability after 7 days	GCAGTTCTCCCCACCTGATGTGG	PIK3R2	ENSG00000268173	-0.1779375728125896	[11]	[8,9]	-3	hSpCas9	negative selection	3251242
18155908	18155931		+	24336571	A375	viability after 7 days	GCGCTCTGTACCCGTTCCGCCGG	PIK3R2	ENSG00000268173	-0.5543452234940501	[23]	[15,15]	-7	hSpCas9	negative selection	3251243
18155900	18155923		-	24336571	A375	viability after 14 days	ACGGGTACAGAGCGCGGTACTGG	PIK3R2	ENSG00000268173	0.15567478634391163	[18]	[15,22]	2	hSpCas9	negative selection	3309033
18160523	18160546		+	24336571	A375	viability after 14 days	CCCTCTTCTGGTGAAGCTTGTGG	PIK3R2	ENSG00000268173	0.27255436097218977	[13]	[15,15]	3	hSpCas9	negative selection	3309034
18160496	18160519		+	24336571	A375	viability after 14 days	GCAGTTCTCCCCACCTGATGTGG	PIK3R2	ENSG00000268173	-0.13708908460414065	[11]	[8,10]	-1	hSpCas9	negative selection	3309035
18155908	18155931		+	24336571	A375	viability after 14 days	GCGCTCTGTACCCGTTCCGCCGG	PIK3R2	ENSG00000268173	-0.8237769698990749	[23]	[12,11]	-7	hSpCas9	negative selection	3309036
18161052	18161075	19	+	27383988	293T	resistance to West Nile virus (flavivirus)	AGACTGGTCCCTGAGCGACGTGG	PIK3R2	ENSG00000268173	-0.7539010439774191	[257,257]	[0,0]	-5	hSpCas9	positive selection	3385896
18160496	18160519	19	+	27383988	293T	resistance to West Nile virus (flavivirus)	GCAGTTCTCCCCACCTGATGTGG	PIK3R2	ENSG00000268173	-6.163124681677816e-05	[152,152]	[0,0]	0	hSpCas9	positive selection	3385897
18160549	18160572	19	-	27383988	293T	resistance to West Nile virus (flavivirus)	GAACTTACCTGTCCTTTCAATGG	PIK3R2	ENSG00000268173	-0.03729453744579207	[156,156]	[0,0]	0	hSpCas9	positive selection	3385898
18160926	18160949	19	+	26780180	HT29	viability (Avana library 4 designs)	CAGCGAATCTCACTACCGCCCGG	PIK3R2	ENSG00000268173	0.994182431103466	[]	[]	4	hSpCas9	negative selection	3449474
18155966	18155989	19	+	26780180	HT29	viability (Avana library 4 designs)	CGTGCTGGTAGTGAGCCGGGCGG	PIK3R2	ENSG00000268173	3.52250830293087	[]	[]	9	hSpCas9	negative selection	3449475
18156089	18156112	19	-	26780180	HT29	viability (Avana library 4 designs)	GGAACTCCACATAGGTGCCAGGG	PIK3R2	ENSG00000268173	2.02451235836079	[]	[]	7	hSpCas9	negative selection	3449476
18162271	18162294	19	-	26780180	HT29	viability (Avana library 4 designs)	GTACCACTCAGCATCCTGCAGGG	PIK3R2	ENSG00000268173	1.09685385033613	[]	[]	4	hSpCas9	negative selection	3449477
18162271	18162294	19	-	26780180	A375	viability (Avana lentiCRISPRv2)	GTACCACTCAGCATCCTGCAGGG	PIK3R2	ENSG00000268173	1.27334342605694	[]	[]	1	hSpCas9	negative selection	3544255
18160926	18160949	19	+	26780180	A375	viability (Avana lentiCRISPRv2)	CAGCGAATCTCACTACCGCCCGG	PIK3R2	ENSG00000268173	4.16575326587451	[]	[]	7	hSpCas9	negative selection	3544256
18156089	18156112	19	-	26780180	A375	viability (Avana lentiCRISPRv2)	GGAACTCCACATAGGTGCCAGGG	PIK3R2	ENSG00000268173	-0.547795571389499	[]	[]	0	hSpCas9	negative selection	3544257
18155966	18155989	19	+	26780180	A375	viability (Avana lentiCRISPRv2)	CGTGCTGGTAGTGAGCCGGGCGG	PIK3R2	ENSG00000268173	1.8450909876607	[]	[]	2	hSpCas9	negative selection	3544258
18160960	18160983	19	-	26780180	A375	viability (Avana lentiCRISPRv2)	GGCTCCCCTTCACCTGTACGCGG	PIK3R2	ENSG00000268173	5.38554591269362	[]	[]	8	hSpCas9	negative selection	3544259
18162463	18162486	19	+	26780180	A375	viability (Avana lentiCRISPRv2)	GATGCTTCTAGCAAGATCCAGGG	PIK3R2	ENSG00000268173	1.29843535330771	[]	[]	1	hSpCas9	negative selection	3544260
18162271	18162294	19	-	26780180	A375	viability (Avana lentiGuide)	GTACCACTCAGCATCCTGCAGGG	PIK3R2	ENSG00000268173	-4.28425371260779	[]	[]	-7	hSpCas9	negative selection	3652914
18160926	18160949	19	+	26780180	A375	viability (Avana lentiGuide)	CAGCGAATCTCACTACCGCCCGG	PIK3R2	ENSG00000268173	-3.02717042764404	[]	[]	-5	hSpCas9	negative selection	3652915
18156089	18156112	19	-	26780180	A375	viability (Avana lentiGuide)	GGAACTCCACATAGGTGCCAGGG	PIK3R2	ENSG00000268173	10.9356768768599	[]	[]	7	hSpCas9	negative selection	3652916
18155966	18155989	19	+	26780180	A375	viability (Avana lentiGuide)	CGTGCTGGTAGTGAGCCGGGCGG	PIK3R2	ENSG00000268173	22.0115408306158	[]	[]	9	hSpCas9	negative selection	3652917
18160960	18160983	19	-	26780180	A375	viability (Avana lentiGuide)	GGCTCCCCTTCACCTGTACGCGG	PIK3R2	ENSG00000268173	-3.12044926887539	[]	[]	-5	hSpCas9	negative selection	3652918
18162463	18162486	19	+	26780180	A375	viability (Avana lentiGuide)	GATGCTTCTAGCAAGATCCAGGG	PIK3R2	ENSG00000268173	3.95784729472689	[]	[]	4	hSpCas9	negative selection	3652919
18162271	18162294	19	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GTACCACTCAGCATCCTGCAGGG	PIK3R2	ENSG00000268173	-0.07717113384115953	[5]	[4,4]	-1	hSpCas9	positive selection	3761573
18160926	18160949	19	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CAGCGAATCTCACTACCGCCCGG	PIK3R2	ENSG00000268173	0.16865780185354734	[4]	[4,4]	4	hSpCas9	positive selection	3761574
18156089	18156112	19	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGAACTCCACATAGGTGCCAGGG	PIK3R2	ENSG00000268173	-0.16245942618228046	[5]	[4,3]	-3	hSpCas9	positive selection	3761575
18155966	18155989	19	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CGTGCTGGTAGTGAGCCGGGCGG	PIK3R2	ENSG00000268173	0.08444316523598512	[4]	[5,4]	2	hSpCas9	positive selection	3761576
18160960	18160983	19	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGCTCCCCTTCACCTGTACGCGG	PIK3R2	ENSG00000268173	0.2971453957295788	[3]	[5,4]	8	hSpCas9	positive selection	3761577
18162463	18162486	19	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GATGCTTCTAGCAAGATCCAGGG	PIK3R2	ENSG00000268173	0.12434375429861276	[5]	[5,5]	3	hSpCas9	positive selection	3761578
18162271	18162294	19	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GTACCACTCAGCATCCTGCAGGG	PIK3R2	ENSG00000268173	0.24760134698176478	[5]	[5,5]	6	hSpCas9	positive selection	3870180
18160926	18160949	19	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CAGCGAATCTCACTACCGCCCGG	PIK3R2	ENSG00000268173	-0.15522636552186359	[5]	[5,2]	-2	hSpCas9	positive selection	3870181
18156089	18156112	19	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGAACTCCACATAGGTGCCAGGG	PIK3R2	ENSG00000268173	-0.35013168393979377	[5]	[4,2]	-4	hSpCas9	positive selection	3870182
18155966	18155989	19	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CGTGCTGGTAGTGAGCCGGGCGG	PIK3R2	ENSG00000268173	-0.38999201481889606	[4]	[3,1]	-5	hSpCas9	positive selection	3870183
18160960	18160983	19	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGCTCCCCTTCACCTGTACGCGG	PIK3R2	ENSG00000268173	0.3634415235443992	[4]	[5,4]	9	hSpCas9	positive selection	3870184
18162463	18162486	19	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GATGCTTCTAGCAAGATCCAGGG	PIK3R2	ENSG00000268173	0.2673382405584621	[4]	[5,3]	7	hSpCas9	positive selection	3870185
18161052	18161075	19	+	26780180	A375	viability	AGACTGGTCCCTGAGCGACGTGG	PIK3R2	ENSG00000268173	1.39827729138594	[]	[]	7	hSpCas9	negative selection	3980987
18161061	18161084	19	-	26780180	A375	viability	CCCACTGATCCACGTCGCTCAGG	PIK3R2	ENSG00000268173	0.918110418996336	[]	[]	4	hSpCas9	negative selection	3980988
18160549	18160572	19	-	26780180	A375	viability	GAACTTACCTGTCCTTTCAATGG	PIK3R2	ENSG00000268173	1.40712899344708	[]	[]	7	hSpCas9	negative selection	3980989
18160496	18160519	19	+	26780180	A375	viability	GCAGTTCTCCCCACCTGATGTGG	PIK3R2	ENSG00000268173	1.4912225405229	[]	[]	8	hSpCas9	negative selection	3980990
18155908	18155931	19	+	26780180	A375	viability	GCGCTCTGTACCCGTTCCGCCGG	PIK3R2	ENSG00000268173	2.02282517410999	[]	[]	9	hSpCas9	negative selection	3980991
18156056	18156079	19	-	26780180	A375	viability	GCTGCCGTGTGCGCTCGTTGAGG	PIK3R2	ENSG00000268173	1.32287033823984	[]	[]	7	hSpCas9	negative selection	3980992
18161052	18161075	19	+	26780180	HT29	viability (GeCKOv2 library)	AGACTGGTCCCTGAGCGACGTGG	PIK3R2	ENSG00000268173	1.78771331859362	[]	[]	8	hSpCas9	negative selection	4088953
18161061	18161084	19	-	26780180	HT29	viability (GeCKOv2 library)	CCCACTGATCCACGTCGCTCAGG	PIK3R2	ENSG00000268173	0.90103302692212	[]	[]	4	hSpCas9	negative selection	4088954
18160549	18160572	19	-	26780180	HT29	viability (GeCKOv2 library)	GAACTTACCTGTCCTTTCAATGG	PIK3R2	ENSG00000268173	1.49218434354735	[]	[]	7	hSpCas9	negative selection	4088955
18160496	18160519	19	+	26780180	HT29	viability (GeCKOv2 library)	GCAGTTCTCCCCACCTGATGTGG	PIK3R2	ENSG00000268173	1.18056843031239	[]	[]	6	hSpCas9	negative selection	4088956
18155908	18155931	19	+	26780180	HT29	viability (GeCKOv2 library)	GCGCTCTGTACCCGTTCCGCCGG	PIK3R2	ENSG00000268173	1.18931727878365	[]	[]	6	hSpCas9	negative selection	4088957
18156056	18156079	19	-	26780180	HT29	viability (GeCKOv2 library)	GCTGCCGTGTGCGCTCGTTGAGG	PIK3R2	ENSG00000268173	0.62122806108095	[]	[]	2	hSpCas9	negative selection	4088958
18155900	18155923	19	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	ACGGGTACAGAGCGCGGTACTGG	PIK3R2	ENSG00000268173	0.5462214217200123	[4]	[7,1]	9	hSpCas9	positive selection	4160607
18160523	18160546	19	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CCCTCTTCTGGTGAAGCTTGTGG	PIK3R2	ENSG00000268173	-0.1106329593068044	[4]	[2,2]	-3	hSpCas9	positive selection	4160608
18160496	18160519	19	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GCAGTTCTCCCCACCTGATGTGG	PIK3R2	ENSG00000268173	-0.34818871249128996	[3]	[1,1]	-7	hSpCas9	positive selection	4160609
18155908	18155931	19	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GCGCTCTGTACCCGTTCCGCCGG	PIK3R2	ENSG00000268173	-0.3825447425545291	[4]	[2,1]	-7	hSpCas9	positive selection	4160610
18155900	18155923	19	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	ACGGGTACAGAGCGCGGTACTGG	PIK3R2	ENSG00000268173	-0.11385615680161304	[4]	[0,2,5,0]	-2	hSpCas9	positive selection	4224629
18160523	18160546	19	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CCCTCTTCTGGTGAAGCTTGTGG	PIK3R2	ENSG00000268173	-0.497113261715313	[4]	[0,2,1,0]	-7	hSpCas9	positive selection	4224630
18160496	18160519	19	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GCAGTTCTCCCCACCTGATGTGG	PIK3R2	ENSG00000268173	-0.9073039414601123	[3]	[0,0,0,0]	-9	hSpCas9	positive selection	4224631
18155908	18155931	19	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GCGCTCTGTACCCGTTCCGCCGG	PIK3R2	ENSG00000268173	-0.4710729455492384	[4]	[3,0,0,0]	-6	hSpCas9	positive selection	4224632
18155908	18155931	19	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GCGCTCTGTACCCGTTCCGCCGG	PIK3R2	ENSG00000268173	-0.47882121313255943	[3]	[2,1]	-8	hSpCas9	positive selection	4290300
18161061	18161084	19	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCCACTGATCCACGTCGCTCAGG	PIK3R2	ENSG00000268173	-0.04597945874439918	[3]	[3,2]	-1	hSpCas9	positive selection	4290301
18156056	18156079	19	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GCTGCCGTGTGCGCTCGTTGAGG	PIK3R2	ENSG00000268173	-0.0031204600813230423	[3]	[2,1]	0	hSpCas9	positive selection	4290302
18161052	18161075	19	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AGACTGGTCCCTGAGCGACGTGG	PIK3R2	ENSG00000268173	-0.18630155052543346	[4]	[4,1]	-4	hSpCas9	positive selection	4354552
18160496	18160519	19	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GCAGTTCTCCCCACCTGATGTGG	PIK3R2	ENSG00000268173	-0.5084338599135969	[3]	[2,0]	-8	hSpCas9	positive selection	4354553
18160549	18160572	19	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GAACTTACCTGTCCTTTCAATGG	PIK3R2	ENSG00000268173	-0.10585298361870454	[2]	[2,1]	-2	hSpCas9	positive selection	4354554
18156052	18156074	19	-	27760321	OCIAML3	viability	CGTGTGCGCTCGTTGAGGCCGG	PIK3R2	ENSG00000268173	0.37319420682399995	[653,609]	[580,717]	4	hSpCas9	negative selection	4427871
18160954	18160976	19	-	27760321	OCIAML3	viability	CTTCACCTGTACGCGGTGCGGG	PIK3R2	ENSG00000268173	-0.2495527098989771	[593,565]	[388,372]	-3	hSpCas9	negative selection	4427872
18161053	18161075	19	+	27760321	OCIAML3	viability	GACTGGTCCCTGAGCGACGTGG	PIK3R2	ENSG00000268173	-0.03386486511823833	[654,570]	[428,516]	0	hSpCas9	negative selection	4427873
18162453	18162475	19	-	27760321	OCIAML3	viability	GCTAGAAGCATCTCGGACTAGG	PIK3R2	ENSG00000268173	-0.21202231491394677	[570,459]	[290,417]	-2	hSpCas9	negative selection	4427874
18162480	18162502	19	-	27760321	OCIAML3	viability	GGTCAGCGTGTACTCGCCCTGG	PIK3R2	ENSG00000268173	-0.1836581191727596	[684,668]	[412,537]	-2	hSpCas9	negative selection	4427875
18156052	18156074	19	-	27760321	OCIAML2	viability	CGTGTGCGCTCGTTGAGGCCGG	PIK3R2	ENSG00000268173	0.408946778413406	[653,609]	[663,698]	5	hSpCas9	negative selection	4511334
18160954	18160976	19	-	27760321	OCIAML2	viability	CTTCACCTGTACGCGGTGCGGG	PIK3R2	ENSG00000268173	0.01120593977862755	[593,565]	[466,481]	0	hSpCas9	negative selection	4511335
18161053	18161075	19	+	27760321	OCIAML2	viability	GACTGGTCCCTGAGCGACGTGG	PIK3R2	ENSG00000268173	-0.024907858110952197	[654,570]	[405,591]	0	hSpCas9	negative selection	4511336
18162453	18162475	19	-	27760321	OCIAML2	viability	GCTAGAAGCATCTCGGACTAGG	PIK3R2	ENSG00000268173	0.06001469628656439	[570,459]	[364,520]	0	hSpCas9	negative selection	4511337
18162480	18162502	19	-	27760321	OCIAML2	viability	GGTCAGCGTGTACTCGCCCTGG	PIK3R2	ENSG00000268173	-0.038193826833532896	[684,668]	[468,620]	0	hSpCas9	negative selection	4511338
18156052	18156074	19	-	27760321	MV411	viability	CGTGTGCGCTCGTTGAGGCCGG	PIK3R2	ENSG00000268173	-0.19936998931552496	[653,609]	[342,393]	-1	hSpCas9	negative selection	4594797
18160954	18160976	19	-	27760321	MV411	viability	CTTCACCTGTACGCGGTGCGGG	PIK3R2	ENSG00000268173	0.007332970639455982	[593,565]	[377,395]	0	hSpCas9	negative selection	4594798
18161053	18161075	19	+	27760321	MV411	viability	GACTGGTCCCTGAGCGACGTGG	PIK3R2	ENSG00000268173	-0.6730858572690517	[654,570]	[139,422]	-4	hSpCas9	negative selection	4594799
18162453	18162475	19	-	27760321	MV411	viability	GCTAGAAGCATCTCGGACTAGG	PIK3R2	ENSG00000268173	-0.012014269573026426	[570,459]	[436,182]	0	hSpCas9	negative selection	4594800
18162480	18162502	19	-	27760321	MV411	viability	GGTCAGCGTGTACTCGCCCTGG	PIK3R2	ENSG00000268173	-0.39541350625279903	[684,668]	[146,630]	-3	hSpCas9	negative selection	4594801
18156052	18156074	19	-	27760321	HL60	viability	CGTGTGCGCTCGTTGAGGCCGG	PIK3R2	ENSG00000268173	0.358355094621123	[653,609]	[549,780]	4	hSpCas9	negative selection	4678260
18160954	18160976	19	-	27760321	HL60	viability	CTTCACCTGTACGCGGTGCGGG	PIK3R2	ENSG00000268173	-0.19261852266506982	[593,565]	[451,375]	-2	hSpCas9	negative selection	4678261
18161053	18161075	19	+	27760321	HL60	viability	GACTGGTCCCTGAGCGACGTGG	PIK3R2	ENSG00000268173	-0.2554636671370478	[654,570]	[285,558]	-3	hSpCas9	negative selection	4678262
18162453	18162475	19	-	27760321	HL60	viability	GCTAGAAGCATCTCGGACTAGG	PIK3R2	ENSG00000268173	-0.19740632087223184	[570,459]	[222,515]	-2	hSpCas9	negative selection	4678263
18162480	18162502	19	-	27760321	HL60	viability	GGTCAGCGTGTACTCGCCCTGG	PIK3R2	ENSG00000268173	-0.4301636583826639	[684,668]	[440,379]	-5	hSpCas9	negative selection	4678264
18156052	18156074	19	-	27760321	HT1080	viability	CGTGTGCGCTCGTTGAGGCCGG	PIK3R2	ENSG00000268173	0.26136493835812213	[609,475]	[106,425]	1	hSpCas9	negative selection	4761723
18160954	18160976	19	-	27760321	HT1080	viability	CTTCACCTGTACGCGGTGCGGG	PIK3R2	ENSG00000268173	-0.3570730486400676	[565,441]	[214,92]	-2	hSpCas9	negative selection	4761724
18161053	18161075	19	+	27760321	HT1080	viability	GACTGGTCCCTGAGCGACGTGG	PIK3R2	ENSG00000268173	-0.09743186792310143	[570,445]	[122,261]	0	hSpCas9	negative selection	4761725
18162453	18162475	19	-	27760321	HT1080	viability	GCTAGAAGCATCTCGGACTAGG	PIK3R2	ENSG00000268173	1.0629471267235808	[459,358]	[357,321]	6	hSpCas9	negative selection	4761726
18162480	18162502	19	-	27760321	HT1080	viability	GGTCAGCGTGTACTCGCCCTGG	PIK3R2	ENSG00000268173	0.8202680820109147	[668,521]	[331,513]	4	hSpCas9	negative selection	4761727
18156052	18156074	19	-	27760321	HT29	viability after 7 days	CGTGTGCGCTCGTTGAGGCCGG	PIK3R2	ENSG00000268173	-0.14327877209933565	[609,475]	[620,675,597]	-2	hSpCas9	negative selection	4845186
18160954	18160976	19	-	27760321	HT29	viability after 7 days	CTTCACCTGTACGCGGTGCGGG	PIK3R2	ENSG00000268173	-0.22380388165363835	[565,441]	[768,610,321]	-3	hSpCas9	negative selection	4845187
18161053	18161075	19	+	27760321	HT29	viability after 7 days	GACTGGTCCCTGAGCGACGTGG	PIK3R2	ENSG00000268173	-0.6461867402726651	[570,445]	[333,623,286]	-7	hSpCas9	negative selection	4845188
18162453	18162475	19	-	27760321	HT29	viability after 7 days	GCTAGAAGCATCTCGGACTAGG	PIK3R2	ENSG00000268173	-0.020169638744220786	[459,358]	[688,530,365]	0	hSpCas9	negative selection	4845189
18162480	18162502	19	-	27760321	HT29	viability after 7 days	GGTCAGCGTGTACTCGCCCTGG	PIK3R2	ENSG00000268173	0.06655130814478738	[668,521]	[821,749,833]	1	hSpCas9	negative selection	4845190
18156052	18156074	19	-	27760321	HT29	viability after 25 days	CGTGTGCGCTCGTTGAGGCCGG	PIK3R2	ENSG00000268173	-0.031053023194556162	[609,475]	[408,735,697]	0	hSpCas9	negative selection	4928649
18160954	18160976	19	-	27760321	HT29	viability after 25 days	CTTCACCTGTACGCGGTGCGGG	PIK3R2	ENSG00000268173	0.09025546859185035	[565,441]	[671,643,507]	0	hSpCas9	negative selection	4928650
18161053	18161075	19	+	27760321	HT29	viability after 25 days	GACTGGTCCCTGAGCGACGTGG	PIK3R2	ENSG00000268173	-0.25819904701733626	[570,445]	[283,464,747]	-3	hSpCas9	negative selection	4928651
18162453	18162475	19	-	27760321	HT29	viability after 25 days	GCTAGAAGCATCTCGGACTAGG	PIK3R2	ENSG00000268173	-0.04549905918353642	[459,358]	[381,469,518]	0	hSpCas9	negative selection	4928652
18162480	18162502	19	-	27760321	HT29	viability after 25 days	GGTCAGCGTGTACTCGCCCTGG	PIK3R2	ENSG00000268173	0.18835140764723968	[668,521]	[809,659,861]	2	hSpCas9	negative selection	4928653
18156052	18156074	19	-	27760321	HT29	viability after 22 days	CGTGTGCGCTCGTTGAGGCCGG	PIK3R2	ENSG00000268173	0.02649179547140068	[609,475]	[471,662,788]	0	hSpCas9	negative selection	5012112
18160954	18160976	19	-	27760321	HT29	viability after 22 days	CTTCACCTGTACGCGGTGCGGG	PIK3R2	ENSG00000268173	-0.2656280302032905	[565,441]	[393,628,432]	-3	hSpCas9	negative selection	5012113
18161053	18161075	19	+	27760321	HT29	viability after 22 days	GACTGGTCCCTGAGCGACGTGG	PIK3R2	ENSG00000268173	-0.35681265159177505	[570,445]	[496,436,441]	-4	hSpCas9	negative selection	5012114
18162453	18162475	19	-	27760321	HT29	viability after 22 days	GCTAGAAGCATCTCGGACTAGG	PIK3R2	ENSG00000268173	-0.25101895551402365	[459,358]	[456,418,314]	-3	hSpCas9	negative selection	5012115
18162480	18162502	19	-	27760321	HT29	viability after 22 days	GGTCAGCGTGTACTCGCCCTGG	PIK3R2	ENSG00000268173	0.28896547005661777	[668,521]	[717,605,1205]	3	hSpCas9	negative selection	5012116
18156052	18156074	19	-	27760321	HT29	viability after 19 days	CGTGTGCGCTCGTTGAGGCCGG	PIK3R2	ENSG00000268173	0.2548914570910743	[609,475]	[779,795,653]	2	hSpCas9	negative selection	5095575
18160954	18160976	19	-	27760321	HT29	viability after 19 days	CTTCACCTGTACGCGGTGCGGG	PIK3R2	ENSG00000268173	0.05856783143643979	[565,441]	[480,490,807]	0	hSpCas9	negative selection	5095576
18161053	18161075	19	+	27760321	HT29	viability after 19 days	GACTGGTCCCTGAGCGACGTGG	PIK3R2	ENSG00000268173	0.11319012604511336	[570,445]	[982,504,442]	1	hSpCas9	negative selection	5095577
18162453	18162475	19	-	27760321	HT29	viability after 19 days	GCTAGAAGCATCTCGGACTAGG	PIK3R2	ENSG00000268173	0.046524994623013766	[459,358]	[549,432,474]	0	hSpCas9	negative selection	5095578
18162480	18162502	19	-	27760321	HT29	viability after 19 days	GGTCAGCGTGTACTCGCCCTGG	PIK3R2	ENSG00000268173	0.06991480928726312	[668,521]	[725,830,592]	0	hSpCas9	negative selection	5095579
18156052	18156074	19	-	27760321	HT29	viability after 16 days	CGTGTGCGCTCGTTGAGGCCGG	PIK3R2	ENSG00000268173	-0.0304643869987814	[609,475]	[677,563,550]	0	hSpCas9	negative selection	5179038
18160954	18160976	19	-	27760321	HT29	viability after 16 days	CTTCACCTGTACGCGGTGCGGG	PIK3R2	ENSG00000268173	0.23424730595685633	[565,441]	[748,774,470]	2	hSpCas9	negative selection	5179039
18161053	18161075	19	+	27760321	HT29	viability after 16 days	GACTGGTCCCTGAGCGACGTGG	PIK3R2	ENSG00000268173	-0.09418369330775683	[570,445]	[467,445,680]	-1	hSpCas9	negative selection	5179040
18162453	18162475	19	-	27760321	HT29	viability after 16 days	GCTAGAAGCATCTCGGACTAGG	PIK3R2	ENSG00000268173	-0.35238538000145136	[459,358]	[352,357,364]	-4	hSpCas9	negative selection	5179041
18162480	18162502	19	-	27760321	HT29	viability after 16 days	GGTCAGCGTGTACTCGCCCTGG	PIK3R2	ENSG00000268173	0.13681237573686633	[668,521]	[690,827,671]	1	hSpCas9	negative selection	5179042
18156052	18156074	19	-	27760321	HT29	viability after 13 days	CGTGTGCGCTCGTTGAGGCCGG	PIK3R2	ENSG00000268173	-0.11581910720763566	[609,475]	[414,742,585]	-1	hSpCas9	negative selection	5262501
18160954	18160976	19	-	27760321	HT29	viability after 13 days	CTTCACCTGTACGCGGTGCGGG	PIK3R2	ENSG00000268173	-0.40718626014190384	[565,441]	[601,324,397]	-5	hSpCas9	negative selection	5262502
18161053	18161075	19	+	27760321	HT29	viability after 13 days	GACTGGTCCCTGAGCGACGTGG	PIK3R2	ENSG00000268173	-0.46198115429350245	[570,445]	[428,413,440]	-5	hSpCas9	negative selection	5262503
18162453	18162475	19	-	27760321	HT29	viability after 13 days	GCTAGAAGCATCTCGGACTAGG	PIK3R2	ENSG00000268173	-0.40746867283664323	[459,358]	[311,411,350]	-5	hSpCas9	negative selection	5262504
18162480	18162502	19	-	27760321	HT29	viability after 13 days	GGTCAGCGTGTACTCGCCCTGG	PIK3R2	ENSG00000268173	0.3105167113160101	[668,521]	[797,792,971]	4	hSpCas9	negative selection	5262505
18156052	18156074	19	-	27760321	HT29	viability after 10 days	CGTGTGCGCTCGTTGAGGCCGG	PIK3R2	ENSG00000268173	0.1481324377805736	[609,475]	[653,720,874]	2	hSpCas9	negative selection	5345964
18160954	18160976	19	-	27760321	HT29	viability after 10 days	CTTCACCTGTACGCGGTGCGGG	PIK3R2	ENSG00000268173	-0.3704264093554415	[565,441]	[611,524,327]	-5	hSpCas9	negative selection	5345965
18161053	18161075	19	+	27760321	HT29	viability after 10 days	GACTGGTCCCTGAGCGACGTGG	PIK3R2	ENSG00000268173	-0.5991049785999296	[570,445]	[214,622,424]	-6	hSpCas9	negative selection	5345966
18162453	18162475	19	-	27760321	HT29	viability after 10 days	GCTAGAAGCATCTCGGACTAGG	PIK3R2	ENSG00000268173	-0.2380229608834302	[459,358]	[642,309,345]	-3	hSpCas9	negative selection	5345967
18162480	18162502	19	-	27760321	HT29	viability after 10 days	GGTCAGCGTGTACTCGCCCTGG	PIK3R2	ENSG00000268173	0.22293622321060302	[668,521]	[878,980,748]	3	hSpCas9	negative selection	5345968
18156052	18156074	19	-	27760321	MOLM13	viability	CGTGTGCGCTCGTTGAGGCCGG	PIK3R2	ENSG00000268173	0.44488165121030154	[653,609]	[645,348]	3	hSpCas9	negative selection	5429427
18160954	18160976	19	-	27760321	MOLM13	viability	CTTCACCTGTACGCGGTGCGGG	PIK3R2	ENSG00000268173	1.0297846693112669	[593,565]	[574,748]	7	hSpCas9	negative selection	5429428
18161053	18161075	19	+	27760321	MOLM13	viability	GACTGGTCCCTGAGCGACGTGG	PIK3R2	ENSG00000268173	-1.8551112512716865	[654,570]	[49,133]	-7	hSpCas9	negative selection	5429429
18162453	18162475	19	-	27760321	MOLM13	viability	GCTAGAAGCATCTCGGACTAGG	PIK3R2	ENSG00000268173	0.6232944854399478	[570,459]	[572,336]	4	hSpCas9	negative selection	5429430
18162480	18162502	19	-	27760321	MOLM13	viability	GGTCAGCGTGTACTCGCCCTGG	PIK3R2	ENSG00000268173	-0.9580153714167201	[684,668]	[148,237]	-5	hSpCas9	negative selection	5429431
18153159	18153182	19	+	27661255	K562	viability	GGCCAGGCCGCTCGGAACCGTGG	PIK3R2	ENSG00000268173	0.09929546261173305	[230,350]	[244,248]	3	dCas9-KRAB	negative selection	5501938
18153244	18153267	19	+	27661255	K562	viability	GGCTTGGCTTGGTGTGACGGCGG	PIK3R2	ENSG00000268173	0.2559675507579524	[453,427]	[412,427]	8	dCas9-KRAB	negative selection	5501939
18153485	18153508	19	+	27661255	K562	viability	GGGACGGTCGGGGCAGAATGGGG	PIK3R2	ENSG00000268173	-0.18534086505561698	[1770,1921]	[1487,1130]	-5	dCas9-KRAB	negative selection	5501940
18153579	18153602	19	+	27661255	K562	viability	GGGCTTCGAATAGTACCGAGGGG	PIK3R2	ENSG00000268173	0.05277031855286596	[1108,1376]	[1094,966]	1	dCas9-KRAB	negative selection	5501941
18153609	18153632	19	+	27661255	K562	viability	GCATTGTGCGGGGCAGAATGGGG	PIK3R2	ENSG00000268173	-0.060929498443786756	[961,1056]	[761,779]	-2	dCas9-KRAB	negative selection	5501942
18155546	18155569	19	+	27661255	K562	viability	GCCCATGGCCCTCCGTGTGAGGG	PIK3R2	ENSG00000268173	0.150211654739291	[332,356]	[285,321]	5	dCas9-KRAB	negative selection	5501943
18155997	18156020	19	+	27661255	K562	viability	GCGCTGGGCGTGGCCGAGGGTGG	PIK3R2	ENSG00000268173	-0.12544351892861308	[724,717]	[569,492]	-4	dCas9-KRAB	negative selection	5501944
18156021	18156044	19	+	27661255	K562	viability	GAGCGCTGCCCACAGAGCGTGGG	PIK3R2	ENSG00000268173	0.07094140151823561	[539,832]	[556,583]	2	dCas9-KRAB	negative selection	5501945
18155731	18155754	19	-	27661255	K562	viability	GCAGTCACAGGCGACCACAGGGG	PIK3R2	ENSG00000268173	0.3049410328661949	[412,372]	[421,359]	8	dCas9-KRAB	negative selection	5501946
18156029	18156052	19	-	27661255	K562	viability	GCATCCAGCCCACGCTCTGTGGG	PIK3R2	ENSG00000268173	-0.14620460143170133	[147,98]	[85,92]	-5	dCas9-KRAB	negative selection	5501947
18155908	18155931	19	+	27260156	BXPC3	viability	GCGCTCTGTACCCGTTCCGCCGG	PIK3R2	ENSG00000268173	-0.15945019412283534	[770]	[628,787,730,742]	-4	hSpCas9	negative selection	5562760
18161061	18161084	19	-	27260156	BXPC3	viability	CCCACTGATCCACGTCGCTCAGG	PIK3R2	ENSG00000268173	-0.30033397641516923	[977]	[659,893,763,1036]	-6	hSpCas9	negative selection	5562761
18156056	18156079	19	-	27260156	BXPC3	viability	GCTGCCGTGTGCGCTCGTTGAGG	PIK3R2	ENSG00000268173	-0.17770326633930725	[481]	[457,481,466,357]	-4	hSpCas9	negative selection	5562762
18161052	18161075	19	+	27260156	BXPC3	viability	AGACTGGTCCCTGAGCGACGTGG	PIK3R2	ENSG00000268173	-0.6645786216018363	[1192]	[706,759,706,1003]	-8	hSpCas9	negative selection	5627012
18160496	18160519	19	+	27260156	BXPC3	viability	GCAGTTCTCCCCACCTGATGTGG	PIK3R2	ENSG00000268173	-0.2629223478430069	[556]	[384,462,509,607]	-5	hSpCas9	negative selection	5627013
18160549	18160572	19	-	27260156	BXPC3	viability	GAACTTACCTGTCCTTTCAATGG	PIK3R2	ENSG00000268173	0.04288503960944301	[367]	[292,422,365,525]	0	hSpCas9	negative selection	5627014
18155908	18155931	19	+	27260156	A673	viability	GCGCTCTGTACCCGTTCCGCCGG	PIK3R2	ENSG00000268173	-0.044933512076717586	[770]	[960,804,920,910]	-1	hSpCas9	negative selection	5684011
18161061	18161084	19	-	27260156	A673	viability	CCCACTGATCCACGTCGCTCAGG	PIK3R2	ENSG00000268173	-0.14553221851095277	[977]	[1281,918,1040,1029]	-4	hSpCas9	negative selection	5684012
18156056	18156079	19	-	27260156	A673	viability	GCTGCCGTGTGCGCTCGTTGAGG	PIK3R2	ENSG00000268173	-0.04316653672170039	[481]	[547,518,552,628]	-1	hSpCas9	negative selection	5684013
18161052	18161075	19	+	27260156	A673	viability	AGACTGGTCCCTGAGCGACGTGG	PIK3R2	ENSG00000268173	-0.6981637901849532	[1192]	[865,765,967,932]	-9	hSpCas9	negative selection	5748263
18160496	18160519	19	+	27260156	A673	viability	GCAGTTCTCCCCACCTGATGTGG	PIK3R2	ENSG00000268173	-0.3990450631290261	[556]	[491,480,521,532]	-7	hSpCas9	negative selection	5748264
18160549	18160572	19	-	27260156	A673	viability	GAACTTACCTGTCCTTTCAATGG	PIK3R2	ENSG00000268173	0.13689758913345504	[367]	[420,413,565,537]	3	hSpCas9	negative selection	5748265
18155908	18155931	19	+	27260156	A375	viability	GCGCTCTGTACCCGTTCCGCCGG	PIK3R2	ENSG00000268173	-0.7153365224032593	[770]	[532,691,561,437]	-7	hSpCas9	negative selection	5805262
18161061	18161084	19	-	27260156	A375	viability	CCCACTGATCCACGTCGCTCAGG	PIK3R2	ENSG00000268173	-0.6978414183563812	[977]	[600,788,590,828]	-7	hSpCas9	negative selection	5805263
18156056	18156079	19	-	27260156	A375	viability	GCTGCCGTGTGCGCTCGTTGAGG	PIK3R2	ENSG00000268173	-0.40405958475108517	[481]	[414,540,277,475]	-5	hSpCas9	negative selection	5805264
18161052	18161075	19	+	27260156	A375	viability	AGACTGGTCCCTGAGCGACGTGG	PIK3R2	ENSG00000268173	-1.1877164905175919	[1192]	[501,616,774,556]	-8	hSpCas9	negative selection	5869514
18160496	18160519	19	+	27260156	A375	viability	GCAGTTCTCCCCACCTGATGTGG	PIK3R2	ENSG00000268173	-1.3425405443551839	[556]	[280,219,241,274]	-9	hSpCas9	negative selection	5869515
18160549	18160572	19	-	27260156	A375	viability	GAACTTACCTGTCCTTTCAATGG	PIK3R2	ENSG00000268173	-0.0750881556654438	[367]	[447,401,510,283]	-1	hSpCas9	negative selection	5869516
18155908	18155931	19	+	27260156	COLO741	viability	GCGCTCTGTACCCGTTCCGCCGG	PIK3R2	ENSG00000268173	0.12317980146242835	[770]	[1275,1146,828]	2	hSpCas9	negative selection	5926513
18161061	18161084	19	-	27260156	COLO741	viability	CCCACTGATCCACGTCGCTCAGG	PIK3R2	ENSG00000268173	-0.1037496673071755	[977]	[1132,1095,1247]	-2	hSpCas9	negative selection	5926514
18156056	18156079	19	-	27260156	COLO741	viability	GCTGCCGTGTGCGCTCGTTGAGG	PIK3R2	ENSG00000268173	0.02603809143996945	[481]	[634,611,632]	0	hSpCas9	negative selection	5926515
18161052	18161075	19	+	27260156	COLO741	viability	AGACTGGTCCCTGAGCGACGTGG	PIK3R2	ENSG00000268173	-0.4428961686292624	[1192]	[1120,1236,1011]	-7	hSpCas9	negative selection	5990765
18160496	18160519	19	+	27260156	COLO741	viability	GCAGTTCTCCCCACCTGATGTGG	PIK3R2	ENSG00000268173	-0.18032445136926528	[556]	[648,669,569]	-4	hSpCas9	negative selection	5990766
18160549	18160572	19	-	27260156	COLO741	viability	GAACTTACCTGTCCTTTCAATGG	PIK3R2	ENSG00000268173	-0.0039584770829820815	[367]	[445,491,465]	0	hSpCas9	negative selection	5990767
18155908	18155931	19	+	27260156	CAL120	viability	GCGCTCTGTACCCGTTCCGCCGG	PIK3R2	ENSG00000268173	-0.02820448663331543	[770]	[1403,611,876]	0	hSpCas9	negative selection	6047764
18161061	18161084	19	-	27260156	CAL120	viability	CCCACTGATCCACGTCGCTCAGG	PIK3R2	ENSG00000268173	-0.23629847745024735	[977]	[1385,1062,708]	-3	hSpCas9	negative selection	6047765
18156056	18156079	19	-	27260156	CAL120	viability	GCTGCCGTGTGCGCTCGTTGAGG	PIK3R2	ENSG00000268173	0.18852664852298606	[481]	[808,622,637]	3	hSpCas9	negative selection	6047766
18161052	18161075	19	+	27260156	CAL120	viability	AGACTGGTCCCTGAGCGACGTGG	PIK3R2	ENSG00000268173	-0.6216685173276605	[1192]	[1157,957,809]	-7	hSpCas9	negative selection	6112016
18160496	18160519	19	+	27260156	CAL120	viability	GCAGTTCTCCCCACCTGATGTGG	PIK3R2	ENSG00000268173	-0.5604502554474502	[556]	[453,516,436]	-7	hSpCas9	negative selection	6112017
18160549	18160572	19	-	27260156	CAL120	viability	GAACTTACCTGTCCTTTCAATGG	PIK3R2	ENSG00000268173	0.2672256762708296	[367]	[701,487,486]	4	hSpCas9	negative selection	6112018
18155908	18155931	19	+	27260156	CADOES1	viability	GCGCTCTGTACCCGTTCCGCCGG	PIK3R2	ENSG00000268173	-0.49564737004390524	[770]	[602,479,366,586]	-7	hSpCas9	negative selection	6169015
18161061	18161084	19	-	27260156	CADOES1	viability	CCCACTGATCCACGTCGCTCAGG	PIK3R2	ENSG00000268173	-0.32489007602799336	[977]	[721,701,491,998]	-5	hSpCas9	negative selection	6169016
18156056	18156079	19	-	27260156	CADOES1	viability	GCTGCCGTGTGCGCTCGTTGAGG	PIK3R2	ENSG00000268173	-0.06763104248159482	[481]	[395,379,608,321]	-1	hSpCas9	negative selection	6169017
18161052	18161075	19	+	27260156	CADOES1	viability	AGACTGGTCCCTGAGCGACGTGG	PIK3R2	ENSG00000268173	-0.8877337888785839	[1192]	[548,525,714,608]	-9	hSpCas9	negative selection	6233267
18160496	18160519	19	+	27260156	CADOES1	viability	GCAGTTCTCCCCACCTGATGTGG	PIK3R2	ENSG00000268173	-0.5740945864480611	[556]	[363,288,459,275]	-7	hSpCas9	negative selection	6233268
18160549	18160572	19	-	27260156	CADOES1	viability	GAACTTACCTGTCCTTTCAATGG	PIK3R2	ENSG00000268173	0.09462359495673034	[367]	[451,354,355,295]	1	hSpCas9	negative selection	6233269
18155908	18155931	19	+	27260156	EWS502	viability	GCGCTCTGTACCCGTTCCGCCGG	PIK3R2	ENSG00000268173	0.02933544339285521	[770]	[861,729,699,1052]	0	hSpCas9	negative selection	6290266
18161061	18161084	19	-	27260156	EWS502	viability	CCCACTGATCCACGTCGCTCAGG	PIK3R2	ENSG00000268173	-0.16487662308397555	[977]	[1071,1002,679,911]	-3	hSpCas9	negative selection	6290267
18156056	18156079	19	-	27260156	EWS502	viability	GCTGCCGTGTGCGCTCGTTGAGG	PIK3R2	ENSG00000268173	0.20010306374641845	[481]	[380,739,579,666]	3	hSpCas9	negative selection	6290268
18161052	18161075	19	+	27260156	EWS502	viability	AGACTGGTCCCTGAGCGACGTGG	PIK3R2	ENSG00000268173	-0.6733226240321007	[1192]	[769,734,674,1004]	-8	hSpCas9	negative selection	6354518
18160496	18160519	19	+	27260156	EWS502	viability	GCAGTTCTCCCCACCTGATGTGG	PIK3R2	ENSG00000268173	-0.5212589520678952	[556]	[300,470,493,386]	-7	hSpCas9	negative selection	6354519
18160549	18160572	19	-	27260156	EWS502	viability	GAACTTACCTGTCCTTTCAATGG	PIK3R2	ENSG00000268173	0.0059740442973914565	[367]	[340,440,397,387]	0	hSpCas9	negative selection	6354520
18155908	18155931	19	+	27260156	EW8	viability	GCGCTCTGTACCCGTTCCGCCGG	PIK3R2	ENSG00000268173	-0.39198697137295724	[770]	[598,516,322,503]	-6	hSpCas9	negative selection	6411517
18161061	18161084	19	-	27260156	EW8	viability	CCCACTGATCCACGTCGCTCAGG	PIK3R2	ENSG00000268173	-0.5126413929091967	[977]	[474,457,595,674]	-7	hSpCas9	negative selection	6411518
18156056	18156079	19	-	27260156	EW8	viability	GCTGCCGTGTGCGCTCGTTGAGG	PIK3R2	ENSG00000268173	0.1351480152077893	[481]	[468,404,512,317]	2	hSpCas9	negative selection	6411519
18161052	18161075	19	+	27260156	EW8	viability	AGACTGGTCCCTGAGCGACGTGG	PIK3R2	ENSG00000268173	-1.0894318350764944	[1192]	[461,451,387,525]	-9	hSpCas9	negative selection	6475769
18160496	18160519	19	+	27260156	EW8	viability	GCAGTTCTCCCCACCTGATGTGG	PIK3R2	ENSG00000268173	-0.20060192108055214	[556]	[350,459,361,397]	-4	hSpCas9	negative selection	6475770
18160549	18160572	19	-	27260156	EW8	viability	GAACTTACCTGTCCTTTCAATGG	PIK3R2	ENSG00000268173	0.08708617223573328	[367]	[440,395,231,225]	1	hSpCas9	negative selection	6475771
18155908	18155931	19	+	27260156	CORL105	viability	GCGCTCTGTACCCGTTCCGCCGG	PIK3R2	ENSG00000268173	-0.00987391487474032	[770]	[829,896,1115,774]	0	hSpCas9	negative selection	6532768
18161061	18161084	19	-	27260156	CORL105	viability	CCCACTGATCCACGTCGCTCAGG	PIK3R2	ENSG00000268173	-0.5537253005338444	[977]	[710,657,917,853]	-7	hSpCas9	negative selection	6532769
18156056	18156079	19	-	27260156	CORL105	viability	GCTGCCGTGTGCGCTCGTTGAGG	PIK3R2	ENSG00000268173	0.007470061579977115	[481]	[494,707,431,606]	0	hSpCas9	negative selection	6532770
18161052	18161075	19	+	27260156	CORL105	viability	AGACTGGTCCCTGAGCGACGTGG	PIK3R2	ENSG00000268173	-0.7537887075199736	[1192]	[658,935,1105,647]	-8	hSpCas9	negative selection	6597020
18160496	18160519	19	+	27260156	CORL105	viability	GCAGTTCTCCCCACCTGATGTGG	PIK3R2	ENSG00000268173	-0.748411292070059	[556]	[356,400,468,336]	-8	hSpCas9	negative selection	6597021
18160549	18160572	19	-	27260156	CORL105	viability	GAACTTACCTGTCCTTTCAATGG	PIK3R2	ENSG00000268173	0.02528697870380925	[367]	[301,378,611,483]	0	hSpCas9	negative selection	6597022
18155908	18155931	19	+	27260156	HS294T	viability	GCGCTCTGTACCCGTTCCGCCGG	PIK3R2	ENSG00000268173	0.1806856495704393	[770]	[225,298,362,501]	2	hSpCas9	negative selection	6654019
18161061	18161084	19	-	27260156	HS294T	viability	CCCACTGATCCACGTCGCTCAGG	PIK3R2	ENSG00000268173	-0.5793052591135748	[977]	[142,244,323,321]	-7	hSpCas9	negative selection	6654020
18156056	18156079	19	-	27260156	HS294T	viability	GCTGCCGTGTGCGCTCGTTGAGG	PIK3R2	ENSG00000268173	0.427595684082669	[481]	[142,202,231,472]	6	hSpCas9	negative selection	6654021
18161052	18161075	19	+	27260156	HS294T	viability	AGACTGGTCCCTGAGCGACGTGG	PIK3R2	ENSG00000268173	-1.0290797212111	[1192]	[196,202,250,261]	-9	hSpCas9	negative selection	6718271
18160496	18160519	19	+	27260156	HS294T	viability	GCAGTTCTCCCCACCTGATGTGG	PIK3R2	ENSG00000268173	-0.5095715215602642	[556]	[80,85,173,296]	-6	hSpCas9	negative selection	6718272
18160549	18160572	19	-	27260156	HS294T	viability	GAACTTACCTGTCCTTTCAATGG	PIK3R2	ENSG00000268173	-0.1382445674374736	[367]	[189,111,91,114]	-2	hSpCas9	negative selection	6718273
18155908	18155931	19	+	27260156	HCC44	viability	GCGCTCTGTACCCGTTCCGCCGG	PIK3R2	ENSG00000268173	-0.285975044395674	[770]	[732,624,896,647]	-4	hSpCas9	negative selection	6775270
18161061	18161084	19	-	27260156	HCC44	viability	CCCACTGATCCACGTCGCTCAGG	PIK3R2	ENSG00000268173	0.10509577452308827	[977]	[1154,941,1669,1099]	1	hSpCas9	negative selection	6775271
18156056	18156079	19	-	27260156	HCC44	viability	GCTGCCGTGTGCGCTCGTTGAGG	PIK3R2	ENSG00000268173	-0.153094385232381	[481]	[397,517,419,592]	-3	hSpCas9	negative selection	6775272
18161052	18161075	19	+	27260156	HCC44	viability	AGACTGGTCCCTGAGCGACGTGG	PIK3R2	ENSG00000268173	-0.4716811032534838	[1192]	[1346,605,1252,817]	-6	hSpCas9	negative selection	6839522
18160496	18160519	19	+	27260156	HCC44	viability	GCAGTTCTCCCCACCTGATGTGG	PIK3R2	ENSG00000268173	-0.14405678602907102	[556]	[660,704,456,426]	-2	hSpCas9	negative selection	6839523
18160549	18160572	19	-	27260156	HCC44	viability	GAACTTACCTGTCCTTTCAATGG	PIK3R2	ENSG00000268173	-0.02799931031276154	[367]	[418,401,520,311]	0	hSpCas9	negative selection	6839524
18155908	18155931	19	+	27260156	G402	viability	GCGCTCTGTACCCGTTCCGCCGG	PIK3R2	ENSG00000268173	-0.20784795365107545	[770]	[1362,552,714,693]	-3	hSpCas9	negative selection	6896521
18161061	18161084	19	-	27260156	G402	viability	CCCACTGATCCACGTCGCTCAGG	PIK3R2	ENSG00000268173	-1.1556520272343265	[977]	[677,700,325,468]	-8	hSpCas9	negative selection	6896522
18156056	18156079	19	-	27260156	G402	viability	GCTGCCGTGTGCGCTCGTTGAGG	PIK3R2	ENSG00000268173	-0.7319686690871688	[481]	[260,282,446,403]	-7	hSpCas9	negative selection	6896523
18161052	18161075	19	+	27260156	G402	viability	AGACTGGTCCCTGAGCGACGTGG	PIK3R2	ENSG00000268173	-1.1953879156891445	[1192]	[703,664,594,589]	-8	hSpCas9	negative selection	6960773
18160496	18160519	19	+	27260156	G402	viability	GCAGTTCTCCCCACCTGATGTGG	PIK3R2	ENSG00000268173	-1.7273472198921536	[556]	[277,236,226,95]	-9	hSpCas9	negative selection	6960774
18160549	18160572	19	-	27260156	G402	viability	GAACTTACCTGTCCTTTCAATGG	PIK3R2	ENSG00000268173	-0.5493283847127288	[367]	[268,451,176,329]	-6	hSpCas9	negative selection	6960775
18155908	18155931	19	+	27260156	L33	viability	GCGCTCTGTACCCGTTCCGCCGG	PIK3R2	ENSG00000268173	-0.06027193165699052	[770]	[716,292,485,752]	-1	hSpCas9	negative selection	7017772
18161061	18161084	19	-	27260156	L33	viability	CCCACTGATCCACGTCGCTCAGG	PIK3R2	ENSG00000268173	-0.3492304084887041	[977]	[727,327,501,744]	-7	hSpCas9	negative selection	7017773
18156056	18156079	19	-	27260156	L33	viability	GCTGCCGTGTGCGCTCGTTGAGG	PIK3R2	ENSG00000268173	0.010792688625553805	[481]	[481,197,318,469]	0	hSpCas9	negative selection	7017774
18161052	18161075	19	+	27260156	L33	viability	AGACTGGTCCCTGAGCGACGTGG	PIK3R2	ENSG00000268173	-0.7344611484277307	[1192]	[582,278,535,754]	-9	hSpCas9	negative selection	7082024
18160496	18160519	19	+	27260156	L33	viability	GCAGTTCTCCCCACCTGATGTGG	PIK3R2	ENSG00000268173	-0.2505912381828305	[556]	[439,203,275,495]	-5	hSpCas9	negative selection	7082025
18160549	18160572	19	-	27260156	L33	viability	GAACTTACCTGTCCTTTCAATGG	PIK3R2	ENSG00000268173	-0.19928933585133196	[367]	[260,159,190,327]	-4	hSpCas9	negative selection	7082026
18155908	18155931	19	+	27260156	K562	viability	GCGCTCTGTACCCGTTCCGCCGG	PIK3R2	ENSG00000268173	-0.3188007937114038	[770]	[652,497,358,672]	-4	hSpCas9	negative selection	7139023
18161061	18161084	19	-	27260156	K562	viability	CCCACTGATCCACGTCGCTCAGG	PIK3R2	ENSG00000268173	-0.6709773165661012	[977]	[629,589,455,514]	-7	hSpCas9	negative selection	7139024
18156056	18156079	19	-	27260156	K562	viability	GCTGCCGTGTGCGCTCGTTGAGG	PIK3R2	ENSG00000268173	-0.2255909740572634	[481]	[351,516,256,344]	-3	hSpCas9	negative selection	7139025
18161052	18161075	19	+	27260156	K562	viability	AGACTGGTCCCTGAGCGACGTGG	PIK3R2	ENSG00000268173	-0.665274509028762	[1192]	[534,681,589,830]	-7	hSpCas9	negative selection	7203275
18160496	18160519	19	+	27260156	K562	viability	GCAGTTCTCCCCACCTGATGTGG	PIK3R2	ENSG00000268173	-1.037139607853404	[556]	[324,235,241,173]	-8	hSpCas9	negative selection	7203276
18160549	18160572	19	-	27260156	K562	viability	GAACTTACCTGTCCTTTCAATGG	PIK3R2	ENSG00000268173	0.28882354526330045	[367]	[482,299,377,430]	3	hSpCas9	negative selection	7203277
18155908	18155931	19	+	27260156	HT29	viability	GCGCTCTGTACCCGTTCCGCCGG	PIK3R2	ENSG00000268173	-0.14570518619127237	[770]	[946,1004,677,781]	-3	hSpCas9	negative selection	7260274
18161061	18161084	19	-	27260156	HT29	viability	CCCACTGATCCACGTCGCTCAGG	PIK3R2	ENSG00000268173	-0.08349035778924008	[977]	[968,1194,1157,1148]	-2	hSpCas9	negative selection	7260275
18156056	18156079	19	-	27260156	HT29	viability	GCTGCCGTGTGCGCTCGTTGAGG	PIK3R2	ENSG00000268173	-0.014367335750020999	[481]	[398,703,710,507]	0	hSpCas9	negative selection	7260276
18161052	18161075	19	+	27260156	HT29	viability	AGACTGGTCCCTGAGCGACGTGG	PIK3R2	ENSG00000268173	-0.7995369162492487	[1192]	[877,1027,850,616]	-8	hSpCas9	negative selection	7324526
18160496	18160519	19	+	27260156	HT29	viability	GCAGTTCTCCCCACCTGATGTGG	PIK3R2	ENSG00000268173	-0.2746515815681435	[556]	[419,713,522,577]	-5	hSpCas9	negative selection	7324527
18160549	18160572	19	-	27260156	HT29	viability	GAACTTACCTGTCCTTTCAATGG	PIK3R2	ENSG00000268173	-0.00045442137226753276	[367]	[434,414,485,445]	0	hSpCas9	negative selection	7324528
18155908	18155931	19	+	27260156	MHHES1	viability	GCGCTCTGTACCCGTTCCGCCGG	PIK3R2	ENSG00000268173	-0.11541782769928632	[770]	[1102,1101,482,609]	-2	hSpCas9	negative selection	7381525
18161061	18161084	19	-	27260156	MHHES1	viability	CCCACTGATCCACGTCGCTCAGG	PIK3R2	ENSG00000268173	-0.4265183299409653	[977]	[858,788,956,687]	-7	hSpCas9	negative selection	7381526
18156056	18156079	19	-	27260156	MHHES1	viability	GCTGCCGTGTGCGCTCGTTGAGG	PIK3R2	ENSG00000268173	-0.31969763174220367	[481]	[480,298,471,462]	-5	hSpCas9	negative selection	7381527
18161052	18161075	19	+	27260156	MHHES1	viability	AGACTGGTCCCTGAGCGACGTGG	PIK3R2	ENSG00000268173	-0.8607238184783851	[1192]	[928,911,604,574]	-9	hSpCas9	negative selection	7445777
18160496	18160519	19	+	27260156	MHHES1	viability	GCAGTTCTCCCCACCTGATGTGG	PIK3R2	ENSG00000268173	-0.4518304027062602	[556]	[561,366,560,360]	-7	hSpCas9	negative selection	7445778
18160549	18160572	19	-	27260156	MHHES1	viability	GAACTTACCTGTCCTTTCAATGG	PIK3R2	ENSG00000268173	0.34362054935126607	[367]	[567,441,424,627]	6	hSpCas9	negative selection	7445779
18155908	18155931	19	+	27260156	MEWO	viability	GCGCTCTGTACCCGTTCCGCCGG	PIK3R2	ENSG00000268173	0.10681730371060405	[770]	[830,692,816]	2	hSpCas9	negative selection	7502776
18161061	18161084	19	-	27260156	MEWO	viability	CCCACTGATCCACGTCGCTCAGG	PIK3R2	ENSG00000268173	-0.11127179936511389	[977]	[885,752,909]	-2	hSpCas9	negative selection	7502777
18156056	18156079	19	-	27260156	MEWO	viability	GCTGCCGTGTGCGCTCGTTGAGG	PIK3R2	ENSG00000268173	0.005431697492869439	[481]	[575,395,409]	0	hSpCas9	negative selection	7502778
18161052	18161075	19	+	27260156	MEWO	viability	AGACTGGTCCCTGAGCGACGTGG	PIK3R2	ENSG00000268173	-0.4951942438328427	[1192]	[1056,740,628]	-8	hSpCas9	negative selection	7567028
18160496	18160519	19	+	27260156	MEWO	viability	GCAGTTCTCCCCACCTGATGTGG	PIK3R2	ENSG00000268173	-0.05673942242094246	[556]	[643,423,462]	-1	hSpCas9	negative selection	7567029
18160549	18160572	19	-	27260156	MEWO	viability	GAACTTACCTGTCCTTTCAATGG	PIK3R2	ENSG00000268173	-0.10856356768945491	[367]	[369,264,332]	-2	hSpCas9	negative selection	7567030
18155908	18155931	19	+	27260156	LNCAPCLONEFGC	viability	GCGCTCTGTACCCGTTCCGCCGG	PIK3R2	ENSG00000268173	-0.22833953749475694	[770]	[609,465,793,551]	-4	hSpCas9	negative selection	7624027
18161061	18161084	19	-	27260156	LNCAPCLONEFGC	viability	CCCACTGATCCACGTCGCTCAGG	PIK3R2	ENSG00000268173	-0.3725024965208764	[977]	[718,533,750,751]	-5	hSpCas9	negative selection	7624028
18156056	18156079	19	-	27260156	LNCAPCLONEFGC	viability	GCTGCCGTGTGCGCTCGTTGAGG	PIK3R2	ENSG00000268173	0.21628163421265287	[481]	[509,507,550,465]	3	hSpCas9	negative selection	7624029
18161052	18161075	19	+	27260156	LNCAPCLONEFGC	viability	AGACTGGTCCCTGAGCGACGTGG	PIK3R2	ENSG00000268173	-0.8883859281856576	[1192]	[540,405,890,554]	-8	hSpCas9	negative selection	7688279
18160496	18160519	19	+	27260156	LNCAPCLONEFGC	viability	GCAGTTCTCCCCACCTGATGTGG	PIK3R2	ENSG00000268173	-0.8841941401007222	[556]	[303,257,207,313]	-8	hSpCas9	negative selection	7688280
18160549	18160572	19	-	27260156	LNCAPCLONEFGC	viability	GAACTTACCTGTCCTTTCAATGG	PIK3R2	ENSG00000268173	0.18056117813684297	[367]	[438,267,525,305]	3	hSpCas9	negative selection	7688281
18155908	18155931	19	+	27260156	PANC0327	viability	GCGCTCTGTACCCGTTCCGCCGG	PIK3R2	ENSG00000268173	-0.1451467285209831	[770]	[628,384,610,882]	-2	hSpCas9	negative selection	7745278
18161061	18161084	19	-	27260156	PANC0327	viability	CCCACTGATCCACGTCGCTCAGG	PIK3R2	ENSG00000268173	-0.5328438554175392	[977]	[617,432,730,642]	-6	hSpCas9	negative selection	7745279
18156056	18156079	19	-	27260156	PANC0327	viability	GCTGCCGTGTGCGCTCGTTGAGG	PIK3R2	ENSG00000268173	-0.2699144717388621	[481]	[419,235,369,414]	-4	hSpCas9	negative selection	7745280
18161052	18161075	19	+	27260156	PANC0327	viability	AGACTGGTCCCTGAGCGACGTGG	PIK3R2	ENSG00000268173	-0.8102713509772259	[1192]	[810,612,529,478]	-8	hSpCas9	negative selection	7809530
18160496	18160519	19	+	27260156	PANC0327	viability	GCAGTTCTCCCCACCTGATGTGG	PIK3R2	ENSG00000268173	-0.6344763564553532	[556]	[322,171,315,482]	-7	hSpCas9	negative selection	7809531
18160549	18160572	19	-	27260156	PANC0327	viability	GAACTTACCTGTCCTTTCAATGG	PIK3R2	ENSG00000268173	-0.37097636657761707	[367]	[333,112,388,199]	-5	hSpCas9	negative selection	7809532
18155908	18155931	19	+	27260156	NCIH2009	viability	GCGCTCTGTACCCGTTCCGCCGG	PIK3R2	ENSG00000268173	-0.15099150738220257	[770]	[1204,929,820]	-2	hSpCas9	negative selection	7866529
18161061	18161084	19	-	27260156	NCIH2009	viability	CCCACTGATCCACGTCGCTCAGG	PIK3R2	ENSG00000268173	-0.1278088419223643	[977]	[1486,1323,983]	-2	hSpCas9	negative selection	7866530
18156056	18156079	19	-	27260156	NCIH2009	viability	GCTGCCGTGTGCGCTCGTTGAGG	PIK3R2	ENSG00000268173	0.011559929638445675	[481]	[808,574,678]	0	hSpCas9	negative selection	7866531
18161052	18161075	19	+	27260156	NCIH2009	viability	AGACTGGTCCCTGAGCGACGTGG	PIK3R2	ENSG00000268173	-1.1237489622105392	[1192]	[793,772,731]	-8	hSpCas9	negative selection	7930781
18160496	18160519	19	+	27260156	NCIH2009	viability	GCAGTTCTCCCCACCTGATGTGG	PIK3R2	ENSG00000268173	-1.0753768451441288	[556]	[447,414,258]	-8	hSpCas9	negative selection	7930782
18160549	18160572	19	-	27260156	NCIH2009	viability	GAACTTACCTGTCCTTTCAATGG	PIK3R2	ENSG00000268173	-0.10588145843332097	[367]	[497,339,600]	-1	hSpCas9	negative selection	7930783
18155908	18155931	19	+	27260156	NCIH1373	viability	GCGCTCTGTACCCGTTCCGCCGG	PIK3R2	ENSG00000268173	-0.2893459782020421	[770]	[961,472,665,208]	-3	hSpCas9	negative selection	7987780
18161061	18161084	19	-	27260156	NCIH1373	viability	CCCACTGATCCACGTCGCTCAGG	PIK3R2	ENSG00000268173	-0.5897854040508634	[977]	[696,735,816,169]	-5	hSpCas9	negative selection	7987781
18156056	18156079	19	-	27260156	NCIH1373	viability	GCTGCCGTGTGCGCTCGTTGAGG	PIK3R2	ENSG00000268173	-1.0868059948977373	[481]	[221,300,175,81]	-8	hSpCas9	negative selection	7987782
18161052	18161075	19	+	27260156	NCIH1373	viability	AGACTGGTCCCTGAGCGACGTGG	PIK3R2	ENSG00000268173	-0.3851790095381047	[1192]	[1301,607,1495,195]	-4	hSpCas9	negative selection	8052032
18160496	18160519	19	+	27260156	NCIH1373	viability	GCAGTTCTCCCCACCTGATGTGG	PIK3R2	ENSG00000268173	-1.6422710491274355	[556]	[141,220,134,77]	-9	hSpCas9	negative selection	8052033
18160549	18160572	19	-	27260156	NCIH1373	viability	GAACTTACCTGTCCTTTCAATGG	PIK3R2	ENSG00000268173	-0.06026739649095009	[367]	[337,424,380,111]	0	hSpCas9	negative selection	8052034
18155908	18155931	19	+	27260156	PATU8902	viability	GCGCTCTGTACCCGTTCCGCCGG	PIK3R2	ENSG00000268173	-0.8514029028912204	[770]	[410,770,519,709]	-7	hSpCas9	negative selection	8109031
18161061	18161084	19	-	27260156	PATU8902	viability	CCCACTGATCCACGTCGCTCAGG	PIK3R2	ENSG00000268173	-1.2196105613595027	[977]	[945,250,370,847]	-8	hSpCas9	negative selection	8109032
18156056	18156079	19	-	27260156	PATU8902	viability	GCTGCCGTGTGCGCTCGTTGAGG	PIK3R2	ENSG00000268173	-0.767592908091557	[481]	[531,371,147,609]	-6	hSpCas9	negative selection	8109033
18161052	18161075	19	+	27260156	PATU8902	viability	AGACTGGTCCCTGAGCGACGTGG	PIK3R2	ENSG00000268173	-0.9508943559093581	[1192]	[846,1300,795,456]	-7	hSpCas9	negative selection	8173283
18160496	18160519	19	+	27260156	PATU8902	viability	GCAGTTCTCCCCACCTGATGTGG	PIK3R2	ENSG00000268173	-2.159887730895259	[556]	[211,89,117,301]	-9	hSpCas9	negative selection	8173284
18160549	18160572	19	-	27260156	PATU8902	viability	GAACTTACCTGTCCTTTCAATGG	PIK3R2	ENSG00000268173	-0.6795596037154517	[367]	[377,538,264,80]	-6	hSpCas9	negative selection	8173285
18155908	18155931	19	+	27260156	PANC1	viability	GCGCTCTGTACCCGTTCCGCCGG	PIK3R2	ENSG00000268173	-0.6520416223281987	[770]	[411,598,432,292]	-7	hSpCas9	negative selection	8230282
18161061	18161084	19	-	27260156	PANC1	viability	CCCACTGATCCACGTCGCTCAGG	PIK3R2	ENSG00000268173	-0.13861138468847511	[977]	[902,717,793,633]	-2	hSpCas9	negative selection	8230283
18156056	18156079	19	-	27260156	PANC1	viability	GCTGCCGTGTGCGCTCGTTGAGG	PIK3R2	ENSG00000268173	-0.14729545926833737	[481]	[321,276,529,346]	-2	hSpCas9	negative selection	8230284
18161052	18161075	19	+	27260156	PANC1	viability	AGACTGGTCCCTGAGCGACGTGG	PIK3R2	ENSG00000268173	-1.0470218645670228	[1192]	[437,660,488,432]	-8	hSpCas9	negative selection	8294534
18160496	18160519	19	+	27260156	PANC1	viability	GCAGTTCTCCCCACCTGATGTGG	PIK3R2	ENSG00000268173	-0.7349147843993431	[556]	[343,414,210,211]	-8	hSpCas9	negative selection	8294535
18160549	18160572	19	-	27260156	PANC1	viability	GAACTTACCTGTCCTTTCAATGG	PIK3R2	ENSG00000268173	-0.09498514755025361	[367]	[222,394,407,192]	-1	hSpCas9	negative selection	8294536
18155908	18155931	19	+	27260156	PANC0813	viability	GCGCTCTGTACCCGTTCCGCCGG	PIK3R2	ENSG00000268173	-0.11474272516358364	[770]	[813,922,874,735]	-2	hSpCas9	negative selection	8351533
18161061	18161084	19	-	27260156	PANC0813	viability	CCCACTGATCCACGTCGCTCAGG	PIK3R2	ENSG00000268173	-0.4506465620367254	[977]	[1057,744,811,769]	-6	hSpCas9	negative selection	8351534
18156056	18156079	19	-	27260156	PANC0813	viability	GCTGCCGTGTGCGCTCGTTGAGG	PIK3R2	ENSG00000268173	0.1269989214777556	[481]	[822,710,515,449]	2	hSpCas9	negative selection	8351535
18161052	18161075	19	+	27260156	PANC0813	viability	AGACTGGTCCCTGAGCGACGTGG	PIK3R2	ENSG00000268173	-0.46611501838176395	[1192]	[1197,1069,875,932]	-6	hSpCas9	negative selection	8415785
18160496	18160519	19	+	27260156	PANC0813	viability	GCAGTTCTCCCCACCTGATGTGG	PIK3R2	ENSG00000268173	-0.6827278197551712	[556]	[540,258,360,476]	-7	hSpCas9	negative selection	8415786
18160549	18160572	19	-	27260156	PANC0813	viability	GAACTTACCTGTCCTTTCAATGG	PIK3R2	ENSG00000268173	0.13391870874258485	[367]	[449,792,336,321]	2	hSpCas9	negative selection	8415787
18155908	18155931	19	+	27260156	RDES	viability	GCGCTCTGTACCCGTTCCGCCGG	PIK3R2	ENSG00000268173	-0.2197931638814976	[770]	[833,625,712,854]	-4	hSpCas9	negative selection	8472784
18161061	18161084	19	-	27260156	RDES	viability	CCCACTGATCCACGTCGCTCAGG	PIK3R2	ENSG00000268173	-0.25034895208052577	[977]	[860,799,874,1299]	-4	hSpCas9	negative selection	8472785
18156056	18156079	19	-	27260156	RDES	viability	GCTGCCGTGTGCGCTCGTTGAGG	PIK3R2	ENSG00000268173	0.029677201954064092	[481]	[491,557,517,714]	0	hSpCas9	negative selection	8472786
18161052	18161075	19	+	27260156	RDES	viability	AGACTGGTCCCTGAGCGACGTGG	PIK3R2	ENSG00000268173	-0.7986305154513327	[1192]	[639,876,798,846]	-8	hSpCas9	negative selection	8537036
18160496	18160519	19	+	27260156	RDES	viability	GCAGTTCTCCCCACCTGATGTGG	PIK3R2	ENSG00000268173	-0.7918608981892116	[556]	[304,367,408,407]	-8	hSpCas9	negative selection	8537037
18160549	18160572	19	-	27260156	RDES	viability	GAACTTACCTGTCCTTTCAATGG	PIK3R2	ENSG00000268173	0.26030218291212925	[367]	[412,472,662,489]	4	hSpCas9	negative selection	8537038
18155908	18155931	19	+	27260156	PC3	viability	GCGCTCTGTACCCGTTCCGCCGG	PIK3R2	ENSG00000268173	-0.4189094578138489	[770]	[283,512,1108,692]	-7	hSpCas9	negative selection	8594035
18161061	18161084	19	-	27260156	PC3	viability	CCCACTGATCCACGTCGCTCAGG	PIK3R2	ENSG00000268173	-0.17385336545523655	[977]	[513,908,1502,848]	-4	hSpCas9	negative selection	8594036
18156056	18156079	19	-	27260156	PC3	viability	GCTGCCGTGTGCGCTCGTTGAGG	PIK3R2	ENSG00000268173	-0.04262320451105665	[481]	[235,418,698,677]	-1	hSpCas9	negative selection	8594037
18161052	18161075	19	+	27260156	PC3	viability	AGACTGGTCCCTGAGCGACGTGG	PIK3R2	ENSG00000268173	-0.9447380576217672	[1192]	[445,619,903,618]	-9	hSpCas9	negative selection	8658287
18160496	18160519	19	+	27260156	PC3	viability	GCAGTTCTCCCCACCTGATGTGG	PIK3R2	ENSG00000268173	-0.2749015461350491	[556]	[292,569,738,357]	-6	hSpCas9	negative selection	8658288
18160549	18160572	19	-	27260156	PC3	viability	GAACTTACCTGTCCTTTCAATGG	PIK3R2	ENSG00000268173	-0.24806410907853432	[367]	[176,381,536,250]	-5	hSpCas9	negative selection	8658289
18155908	18155931	19	+	27260156	PATU8988T	viability	GCGCTCTGTACCCGTTCCGCCGG	PIK3R2	ENSG00000268173	-0.7009095066245812	[770]	[345,495,531,461]	-8	hSpCas9	negative selection	8715286
18161061	18161084	19	-	27260156	PATU8988T	viability	CCCACTGATCCACGTCGCTCAGG	PIK3R2	ENSG00000268173	-0.5065102358849009	[977]	[495,836,616,732]	-7	hSpCas9	negative selection	8715287
18156056	18156079	19	-	27260156	PATU8988T	viability	GCTGCCGTGTGCGCTCGTTGAGG	PIK3R2	ENSG00000268173	-0.24332651939517067	[481]	[296,399,327,563]	-4	hSpCas9	negative selection	8715288
18161052	18161075	19	+	27260156	PATU8988T	viability	AGACTGGTCCCTGAGCGACGTGG	PIK3R2	ENSG00000268173	-0.6242997440005033	[1192]	[914,631,669,765]	-7	hSpCas9	negative selection	8779538
18160496	18160519	19	+	27260156	PATU8988T	viability	GCAGTTCTCCCCACCTGATGTGG	PIK3R2	ENSG00000268173	-1.3275722859872505	[556]	[134,228,232,265]	-9	hSpCas9	negative selection	8779539
18160549	18160572	19	-	27260156	PATU8988T	viability	GAACTTACCTGTCCTTTCAATGG	PIK3R2	ENSG00000268173	-0.4962880568747207	[367]	[194,448,155,225]	-7	hSpCas9	negative selection	8779540
18155908	18155931	19	+	27260156	T47D	viability	GCGCTCTGTACCCGTTCCGCCGG	PIK3R2	ENSG00000268173	-0.2905872798831711	[770]	[769,700,717,751]	-6	hSpCas9	negative selection	8836537
18161061	18161084	19	-	27260156	T47D	viability	CCCACTGATCCACGTCGCTCAGG	PIK3R2	ENSG00000268173	-0.31853564997199546	[977]	[867,787,993,1016]	-6	hSpCas9	negative selection	8836538
18156056	18156079	19	-	27260156	T47D	viability	GCTGCCGTGTGCGCTCGTTGAGG	PIK3R2	ENSG00000268173	-0.016911573743997547	[481]	[520,532,562,605]	0	hSpCas9	negative selection	8836539
18161052	18161075	19	+	27260156	T47D	viability	AGACTGGTCCCTGAGCGACGTGG	PIK3R2	ENSG00000268173	-0.8374439511437789	[1192]	[801,834,557,918]	-9	hSpCas9	negative selection	8900789
18160496	18160519	19	+	27260156	T47D	viability	GCAGTTCTCCCCACCTGATGTGG	PIK3R2	ENSG00000268173	-0.41879903191551904	[556]	[500,501,443,493]	-7	hSpCas9	negative selection	8900790
18160549	18160572	19	-	27260156	T47D	viability	GAACTTACCTGTCCTTTCAATGG	PIK3R2	ENSG00000268173	0.14047784929312754	[367]	[430,432,535,492]	3	hSpCas9	negative selection	8900791
18155908	18155931	19	+	27260156	SU8686	viability	GCGCTCTGTACCCGTTCCGCCGG	PIK3R2	ENSG00000268173	0.13794967975534067	[770]	[882,622,761,1163]	2	hSpCas9	negative selection	8957788
18161061	18161084	19	-	27260156	SU8686	viability	CCCACTGATCCACGTCGCTCAGG	PIK3R2	ENSG00000268173	-0.46684155230823565	[977]	[596,694,768,764]	-6	hSpCas9	negative selection	8957789
18156056	18156079	19	-	27260156	SU8686	viability	GCTGCCGTGTGCGCTCGTTGAGG	PIK3R2	ENSG00000268173	-0.03295813007344253	[481]	[456,368,446,631]	0	hSpCas9	negative selection	8957790
18161052	18161075	19	+	27260156	SU8686	viability	AGACTGGTCCCTGAGCGACGTGG	PIK3R2	ENSG00000268173	-0.750756015230411	[1192]	[743,571,836,662]	-8	hSpCas9	negative selection	9022040
18160496	18160519	19	+	27260156	SU8686	viability	GCAGTTCTCCCCACCTGATGTGG	PIK3R2	ENSG00000268173	-0.7584375453261567	[556]	[287,301,295,442]	-8	hSpCas9	negative selection	9022041
18160549	18160572	19	-	27260156	SU8686	viability	GAACTTACCTGTCCTTTCAATGG	PIK3R2	ENSG00000268173	-0.22132871921305036	[367]	[373,302,264,297]	-4	hSpCas9	negative selection	9022042
18155908	18155931	19	+	27260156	SKES1	viability	GCGCTCTGTACCCGTTCCGCCGG	PIK3R2	ENSG00000268173	-0.19473868505810754	[770]	[827,779,567,554]	-4	hSpCas9	negative selection	9079039
18161061	18161084	19	-	27260156	SKES1	viability	CCCACTGATCCACGTCGCTCAGG	PIK3R2	ENSG00000268173	-0.15931900027580848	[977]	[1076,853,800,789]	-3	hSpCas9	negative selection	9079040
18156056	18156079	19	-	27260156	SKES1	viability	GCTGCCGTGTGCGCTCGTTGAGG	PIK3R2	ENSG00000268173	-0.06257588715057134	[481]	[557,537,339,428]	-1	hSpCas9	negative selection	9079041
18161052	18161075	19	+	27260156	SKES1	viability	AGACTGGTCCCTGAGCGACGTGG	PIK3R2	ENSG00000268173	-0.9844016299278635	[1192]	[721,564,545,581]	-9	hSpCas9	negative selection	9143291
18160496	18160519	19	+	27260156	SKES1	viability	GCAGTTCTCCCCACCTGATGTGG	PIK3R2	ENSG00000268173	-0.47825915021439247	[556]	[397,403,486,311]	-8	hSpCas9	negative selection	9143292
18160549	18160572	19	-	27260156	SKES1	viability	GAACTTACCTGTCCTTTCAATGG	PIK3R2	ENSG00000268173	0.06888574613034765	[367]	[349,369,341,458]	1	hSpCas9	negative selection	9143293
18155908	18155931	19	+	27260156	TOV112D	viability	GCGCTCTGTACCCGTTCCGCCGG	PIK3R2	ENSG00000268173	-0.0323784579438271	[770]	[1056,468,873,578]	0	hSpCas9	negative selection	9200290
18161061	18161084	19	-	27260156	TOV112D	viability	CCCACTGATCCACGTCGCTCAGG	PIK3R2	ENSG00000268173	-0.21063589937143212	[977]	[827,1133,549,938]	-4	hSpCas9	negative selection	9200291
18156056	18156079	19	-	27260156	TOV112D	viability	GCTGCCGTGTGCGCTCGTTGAGG	PIK3R2	ENSG00000268173	-0.3382245738758445	[481]	[383,452,343,363]	-6	hSpCas9	negative selection	9200292
18161052	18161075	19	+	27260156	TOV112D	viability	AGACTGGTCCCTGAGCGACGTGG	PIK3R2	ENSG00000268173	-1.0476159501293083	[1192]	[643,738,455,518]	-9	hSpCas9	negative selection	9264542
18160496	18160519	19	+	27260156	TOV112D	viability	GCAGTTCTCCCCACCTGATGTGG	PIK3R2	ENSG00000268173	-0.23180184272634435	[556]	[457,435,540,453]	-4	hSpCas9	negative selection	9264543
18160549	18160572	19	-	27260156	TOV112D	viability	GAACTTACCTGTCCTTTCAATGG	PIK3R2	ENSG00000268173	0.04660810289322531	[367]	[283,774,353,202]	0	hSpCas9	negative selection	9264544
18155908	18155931	19	+	27260156	TC71	viability	GCGCTCTGTACCCGTTCCGCCGG	PIK3R2	ENSG00000268173	-0.10635865463254146	[770]	[795,724,748,802]	-3	hSpCas9	negative selection	9321541
18161061	18161084	19	-	27260156	TC71	viability	CCCACTGATCCACGTCGCTCAGG	PIK3R2	ENSG00000268173	-0.13251759543838282	[977]	[1043,890,953,932]	-3	hSpCas9	negative selection	9321542
18156056	18156079	19	-	27260156	TC71	viability	GCTGCCGTGTGCGCTCGTTGAGG	PIK3R2	ENSG00000268173	-0.02439532893563629	[481]	[499,565,526,433]	0	hSpCas9	negative selection	9321543
18161052	18161075	19	+	27260156	TC71	viability	AGACTGGTCCCTGAGCGACGTGG	PIK3R2	ENSG00000268173	-0.8416217583093818	[1192]	[801,549,774,723]	-9	hSpCas9	negative selection	9385793
18160496	18160519	19	+	27260156	TC71	viability	GCAGTTCTCCCCACCTGATGTGG	PIK3R2	ENSG00000268173	-0.07356525783256401	[556]	[691,546,454,576]	-2	hSpCas9	negative selection	9385794
18160549	18160572	19	-	27260156	TC71	viability	GAACTTACCTGTCCTTTCAATGG	PIK3R2	ENSG00000268173	0.18702809936407336	[367]	[513,316,489,473]	5	hSpCas9	negative selection	9385795
18155908	18155931	19	+	27260156	TC32	viability	GCGCTCTGTACCCGTTCCGCCGG	PIK3R2	ENSG00000268173	-0.045192278530222896	[770]	[700,476,878,833]	-1	hSpCas9	negative selection	9442792
18161061	18161084	19	-	27260156	TC32	viability	CCCACTGATCCACGTCGCTCAGG	PIK3R2	ENSG00000268173	-0.41537890550042866	[977]	[670,497,828,823]	-7	hSpCas9	negative selection	9442793
18156056	18156079	19	-	27260156	TC32	viability	GCTGCCGTGTGCGCTCGTTGAGG	PIK3R2	ENSG00000268173	-0.21746282404690673	[481]	[469,175,565,427]	-4	hSpCas9	negative selection	9442794
18161052	18161075	19	+	27260156	TC32	viability	AGACTGGTCCCTGAGCGACGTGG	PIK3R2	ENSG00000268173	-0.9019104420088488	[1192]	[628,430,746,644]	-9	hSpCas9	negative selection	9507044
18160496	18160519	19	+	27260156	TC32	viability	GCAGTTCTCCCCACCTGATGTGG	PIK3R2	ENSG00000268173	-0.3834161730169635	[556]	[470,325,419,383]	-6	hSpCas9	negative selection	9507045
18160549	18160572	19	-	27260156	TC32	viability	GAACTTACCTGTCCTTTCAATGG	PIK3R2	ENSG00000268173	-0.012209364272138146	[367]	[306,201,514,420]	0	hSpCas9	negative selection	9507046
18155908	18155931	19	+	27869803	HPAFII	viability after 27 days	GCGCTCTGTACCCGTTCCGCCGG	PIK3R2	ENSG00000268173	-1.1890756281538604	[370]	[60,105,NaN]	-7	hSpCas9	negative selection	9566399
18160521	18160544	19	-	27869803	HPAFII	viability after 27 days	ACAAGCTTCACCAGAAGAGGGGG	PIK3R2	ENSG00000268173	-1.2982314875018917	[255]	[75,36,NaN]	-7	hSpCas9	negative selection	9566400
18160915	18160938	19	-	27869803	HPAFII	viability after 27 days	TGAGATTCGCTGTCCAGCCCTGG	PIK3R2	ENSG00000268173	-0.5584862907650604	[286]	[84,116,NaN]	-4	hSpCas9	negative selection	9566401
18161052	18161075	19	+	27869803	HPAFII	viability after 27 days	AGACTGGTCCCTGAGCGACGTGG	PIK3R2	ENSG00000268173	-1.4889888394631354	[513]	[74,113,NaN]	-7	hSpCas9	negative selection	9566402
18161267	18161290	19	+	27869803	HPAFII	viability after 27 days	ATCTGTCCGCAGAGGCCGCGGGG	PIK3R2	ENSG00000268173	-0.5304699338632329	[260]	[166,34,NaN]	-4	hSpCas9	negative selection	9566403
18162014	18162037	19	+	27869803	HPAFII	viability after 27 days	TCAGGAACACTTGGAAGAGCAGG	PIK3R2	ENSG00000268173	-0.6430903727586141	[346]	[70,154,NaN]	-5	hSpCas9	negative selection	9566404
18155908	18155931	19	+	27869803	HPAFII	viability after 15 days	GCGCTCTGTACCCGTTCCGCCGG	PIK3R2	ENSG00000268173	-1.8370929877120097	[370]	[81,129,NaN]	-9	hSpCas9	negative selection	9648848
18160521	18160544	19	-	27869803	HPAFII	viability after 15 days	ACAAGCTTCACCAGAAGAGGGGG	PIK3R2	ENSG00000268173	-0.5429461471570827	[255]	[268,138,NaN]	-5	hSpCas9	negative selection	9648849
18160915	18160938	19	-	27869803	HPAFII	viability after 15 days	TGAGATTCGCTGTCCAGCCCTGG	PIK3R2	ENSG00000268173	-0.015447124855250155	[286]	[261,331,NaN]	0	hSpCas9	negative selection	9648850
18161052	18161075	19	+	27869803	HPAFII	viability after 15 days	AGACTGGTCCCTGAGCGACGTGG	PIK3R2	ENSG00000268173	-0.6176253754452299	[513]	[499,272,NaN]	-6	hSpCas9	negative selection	9648851
18161267	18161290	19	+	27869803	HPAFII	viability after 15 days	ATCTGTCCGCAGAGGCCGCGGGG	PIK3R2	ENSG00000268173	-0.3162084551190209	[260]	[347,148,NaN]	-4	hSpCas9	negative selection	9648852
18162014	18162037	19	+	27869803	HPAFII	viability after 15 days	TCAGGAACACTTGGAAGAGCAGG	PIK3R2	ENSG00000268173	0.007273572229845704	[346]	[544,268,NaN]	0	hSpCas9	negative selection	9648853
18155908	18155931	19	+	27869803	ASPC1	viability after 36 days	GCGCTCTGTACCCGTTCCGCCGG	PIK3R2	ENSG00000268173	-0.04042837653636361	[798]	[202,472,155]	0	hSpCas9	negative selection	9731297
18160521	18160544	19	-	27869803	ASPC1	viability after 36 days	ACAAGCTTCACCAGAAGAGGGGG	PIK3R2	ENSG00000268173	0.29372838385600974	[541]	[30,496,159]	3	hSpCas9	negative selection	9731298
18160915	18160938	19	-	27869803	ASPC1	viability after 36 days	TGAGATTCGCTGTCCAGCCCTGG	PIK3R2	ENSG00000268173	-0.3244951306126048	[966]	[45,428,296]	-3	hSpCas9	negative selection	9731299
18161052	18161075	19	+	27869803	ASPC1	viability after 36 days	AGACTGGTCCCTGAGCGACGTGG	PIK3R2	ENSG00000268173	-0.7337344825620252	[1345]	[168,108,496]	-6	hSpCas9	negative selection	9731300
18161267	18161290	19	+	27869803	ASPC1	viability after 36 days	ATCTGTCCGCAGAGGCCGCGGGG	PIK3R2	ENSG00000268173	1.0649429670913038	[513]	[396,546,219]	8	hSpCas9	negative selection	9731301
18162014	18162037	19	+	27869803	ASPC1	viability after 36 days	TCAGGAACACTTGGAAGAGCAGG	PIK3R2	ENSG00000268173	-0.07132141926404129	[875]	[255,389,233]	0	hSpCas9	negative selection	9731302
18155908	18155931	19	+	27869803	PATU8988S	viability after 35 days	GCGCTCTGTACCCGTTCCGCCGG	PIK3R2	ENSG00000268173	-1.1717659469038282	[625]	[72,150,NaN]	-8	hSpCas9	negative selection	9813746
18160521	18160544	19	-	27869803	PATU8988S	viability after 35 days	ACAAGCTTCACCAGAAGAGGGGG	PIK3R2	ENSG00000268173	-0.7274206473568092	[595]	[135,153,NaN]	-6	hSpCas9	negative selection	9813747
18160915	18160938	19	-	27869803	PATU8988S	viability after 35 days	TGAGATTCGCTGTCCAGCCCTGG	PIK3R2	ENSG00000268173	0.3954994269646084	[714]	[505,250,NaN]	4	hSpCas9	negative selection	9813748
18161052	18161075	19	+	27869803	PATU8988S	viability after 35 days	AGACTGGTCCCTGAGCGACGTGG	PIK3R2	ENSG00000268173	0.08899614191276717	[1163]	[555,440,NaN]	1	hSpCas9	negative selection	9813749
18161267	18161290	19	+	27869803	PATU8988S	viability after 35 days	ATCTGTCCGCAGAGGCCGCGGGG	PIK3R2	ENSG00000268173	0.23140791641186664	[409]	[130,256,NaN]	2	hSpCas9	negative selection	9813750
18162014	18162037	19	+	27869803	PATU8988S	viability after 35 days	TCAGGAACACTTGGAAGAGCAGG	PIK3R2	ENSG00000268173	0.8213358799875204	[640]	[317,594,NaN]	8	hSpCas9	negative selection	9813751
18155908	18155931	19	+	27869803	PATU8988S	viability after 31 days	GCGCTCTGTACCCGTTCCGCCGG	PIK3R2	ENSG00000268173	-0.4551819356616088	[625]	[145,227,NaN]	-5	hSpCas9	negative selection	9896195
18160521	18160544	19	-	27869803	PATU8988S	viability after 31 days	ACAAGCTTCACCAGAAGAGGGGG	PIK3R2	ENSG00000268173	-0.5462026715811721	[595]	[105,234,NaN]	-5	hSpCas9	negative selection	9896196
18160915	18160938	19	-	27869803	PATU8988S	viability after 31 days	TGAGATTCGCTGTCCAGCCCTGG	PIK3R2	ENSG00000268173	0.5511109173511267	[714]	[488,326,NaN]	6	hSpCas9	negative selection	9896197
18161052	18161075	19	+	27869803	PATU8988S	viability after 31 days	AGACTGGTCCCTGAGCGACGTGG	PIK3R2	ENSG00000268173	0.2451353996395922	[1163]	[440,688,NaN]	3	hSpCas9	negative selection	9896198
18161267	18161290	19	+	27869803	PATU8988S	viability after 31 days	ATCTGTCCGCAGAGGCCGCGGGG	PIK3R2	ENSG00000268173	0.10931546582667417	[409]	[145,214,NaN]	1	hSpCas9	negative selection	9896199
18162014	18162037	19	+	27869803	PATU8988S	viability after 31 days	TCAGGAACACTTGGAAGAGCAGG	PIK3R2	ENSG00000268173	0.6494513480621037	[640]	[392,410,NaN]	7	hSpCas9	negative selection	9896200
18155908	18155931	19	+	27869803	HPAFII	viability after 35 days	GCGCTCTGTACCCGTTCCGCCGG	PIK3R2	ENSG00000268173	-1.8678493805916125	[370]	[26,78,NaN]	-7	hSpCas9	negative selection	9978644
18160521	18160544	19	-	27869803	HPAFII	viability after 35 days	ACAAGCTTCACCAGAAGAGGGGG	PIK3R2	ENSG00000268173	-1.6315803192902956	[255]	[46,35,NaN]	-7	hSpCas9	negative selection	9978645
18160915	18160938	19	-	27869803	HPAFII	viability after 35 days	TGAGATTCGCTGTCCAGCCCTGG	PIK3R2	ENSG00000268173	-0.6147045343065647	[286]	[100,87,NaN]	-4	hSpCas9	negative selection	9978646
18161052	18161075	19	+	27869803	HPAFII	viability after 35 days	AGACTGGTCCCTGAGCGACGTGG	PIK3R2	ENSG00000268173	-1.6756126927768962	[513]	[48,117,NaN]	-7	hSpCas9	negative selection	9978647
18161267	18161290	19	+	27869803	HPAFII	viability after 35 days	ATCTGTCCGCAGAGGCCGCGGGG	PIK3R2	ENSG00000268173	-1.9383677431859134	[260]	[41,25,NaN]	-7	hSpCas9	negative selection	9978648
18162014	18162037	19	+	27869803	HPAFII	viability after 35 days	TCAGGAACACTTGGAAGAGCAGG	PIK3R2	ENSG00000268173	-0.22959632972260238	[346]	[27,286,NaN]	-1	hSpCas9	negative selection	9978649
18155908	18155931	19	+	27869803	HPAFII	viability after 31 days	GCGCTCTGTACCCGTTCCGCCGG	PIK3R2	ENSG00000268173	-1.1869929120841916	[370]	[67,116,NaN]	-6	hSpCas9	negative selection	10061093
18160521	18160544	19	-	27869803	HPAFII	viability after 31 days	ACAAGCTTCACCAGAAGAGGGGG	PIK3R2	ENSG00000268173	-1.7970626107379841	[255]	[48,32,NaN]	-7	hSpCas9	negative selection	10061094
18160915	18160938	19	-	27869803	HPAFII	viability after 31 days	TGAGATTCGCTGTCCAGCCCTGG	PIK3R2	ENSG00000268173	-0.2036519192602071	[286]	[80,203,NaN]	-1	hSpCas9	negative selection	10061095
18161052	18161075	19	+	27869803	HPAFII	viability after 31 days	AGACTGGTCCCTGAGCGACGTGG	PIK3R2	ENSG00000268173	-1.3443436150367112	[513]	[48,183,NaN]	-7	hSpCas9	negative selection	10061096
18161267	18161290	19	+	27869803	HPAFII	viability after 31 days	ATCTGTCCGCAGAGGCCGCGGGG	PIK3R2	ENSG00000268173	-1.382036571561063	[260]	[82,26,NaN]	-7	hSpCas9	negative selection	10061097
18162014	18162037	19	+	27869803	HPAFII	viability after 31 days	TCAGGAACACTTGGAAGAGCAGG	PIK3R2	ENSG00000268173	-0.4108748370808667	[346]	[78,219,NaN]	-3	hSpCas9	negative selection	10061098
18156021	18156044	19	+	28162770	P31FUJ	viability	GAGCGCTGCCCACAGAGCGTGGG	PIK3R2	ENSG00000268173	-0.2328022044143787	[71]	[71]	-2	hSpCas9	negative selection	10211387
18162411	18162434	19	+	28162770	P31FUJ	viability	GGAGGTGAACGAGAAACTCCGGG	PIK3R2	ENSG00000268173	-0.45519462575082636	[27]	[23]	-4	hSpCas9	negative selection	10211388
18162017	18162040	19	+	28162770	P31FUJ	viability	GGAACACTTGGAAGAGCAGGAGG	PIK3R2	ENSG00000268173	0.3614680385330057	[205]	[310]	4	hSpCas9	negative selection	10211389
18163277	18163300	19	+	28162770	P31FUJ	viability	GGAGGACAGCGTGGAGGCAGTGG	PIK3R2	ENSG00000268173	-4.42042920759015	[163]	[8]	-9	hSpCas9	negative selection	10211390
18166281	18166304	19	+	28162770	P31FUJ	viability	GCAACGAGAAAGAGATGCAAAGG	PIK3R2	ENSG00000268173	-0.12215814073038611	[137]	[148]	-1	hSpCas9	negative selection	10211391
18168789	18168812	19	+	28162770	P31FUJ	viability	GGGCAAGATCAACCGCACGCAGG	PIK3R2	ENSG00000268173	-0.6478397036932226	[39]	[29]	-5	hSpCas9	negative selection	10211392
18155878	18155901	19	-	28162770	P31FUJ	viability	GAAGCCCTCAGGGCCCGCCATGG	PIK3R2	ENSG00000268173	1.2123026327238169	[183]	[500]	9	hSpCas9	negative selection	10211393
18155966	18155989	19	+	28162770	P31FUJ	viability	CGTGCTGGTAGTGAGCCGGGCGG	PIK3R2	ENSG00000268173	-0.0025045849925844355	[103]	[121]	0	hSpCas9	negative selection	10211394
18156089	18156112	19	-	28162770	P31FUJ	viability	GGAACTCCACATAGGTGCCAGGG	PIK3R2	ENSG00000268173	0.09300932496021186	[370]	[464]	0	hSpCas9	negative selection	10211395
18160481	18160504	19	-	28162770	P31FUJ	viability	AGAACTGCTCGGGCAAGTCGGGG	PIK3R2	ENSG00000268173	0.6159038174366809	[225]	[406]	7	hSpCas9	negative selection	10211396
18156021	18156044	19	+	28162770	TF1	viability	GAGCGCTGCCCACAGAGCGTGGG	PIK3R2	ENSG00000268173	NaN	[NaN]	[23]	1	hSpCas9	negative selection	10380753
18162411	18162434	19	+	28162770	TF1	viability	GGAGGTGAACGAGAAACTCCGGG	PIK3R2	ENSG00000268173	NaN	[NaN]	[19]	1	hSpCas9	negative selection	10380754
18162017	18162040	19	+	28162770	TF1	viability	GGAACACTTGGAAGAGCAGGAGG	PIK3R2	ENSG00000268173	NaN	[NaN]	[166]	1	hSpCas9	negative selection	10380755
18163277	18163300	19	+	28162770	TF1	viability	GGAGGACAGCGTGGAGGCAGTGG	PIK3R2	ENSG00000268173	NaN	[NaN]	[8]	1	hSpCas9	negative selection	10380756
18166281	18166304	19	+	28162770	TF1	viability	GCAACGAGAAAGAGATGCAAAGG	PIK3R2	ENSG00000268173	NaN	[NaN]	[38]	1	hSpCas9	negative selection	10380757
18168789	18168812	19	+	28162770	TF1	viability	GGGCAAGATCAACCGCACGCAGG	PIK3R2	ENSG00000268173	NaN	[NaN]	[36]	1	hSpCas9	negative selection	10380758
18155878	18155901	19	-	28162770	TF1	viability	GAAGCCCTCAGGGCCCGCCATGG	PIK3R2	ENSG00000268173	NaN	[NaN]	[331]	1	hSpCas9	negative selection	10380759
18155966	18155989	19	+	28162770	TF1	viability	CGTGCTGGTAGTGAGCCGGGCGG	PIK3R2	ENSG00000268173	NaN	[NaN]	[47]	1	hSpCas9	negative selection	10380760
18156089	18156112	19	-	28162770	TF1	viability	GGAACTCCACATAGGTGCCAGGG	PIK3R2	ENSG00000268173	NaN	[NaN]	[316]	1	hSpCas9	negative selection	10380761
18160481	18160504	19	-	28162770	TF1	viability	AGAACTGCTCGGGCAAGTCGGGG	PIK3R2	ENSG00000268173	NaN	[NaN]	[86]	1	hSpCas9	negative selection	10380762
18156021	18156044	19	+	28162770	SKM1	viability	GAGCGCTGCCCACAGAGCGTGGG	PIK3R2	ENSG00000268173	-0.4500329206350475	[33]	[43]	-4	hSpCas9	negative selection	10550119
18162411	18162434	19	+	28162770	SKM1	viability	GGAGGTGAACGAGAAACTCCGGG	PIK3R2	ENSG00000268173	-2.237039197300849	[7]	[2]	-8	hSpCas9	negative selection	10550120
18162017	18162040	19	+	28162770	SKM1	viability	GGAACACTTGGAAGAGCAGGAGG	PIK3R2	ENSG00000268173	0.41718596585742074	[60]	[143]	4	hSpCas9	negative selection	10550121
18163277	18163300	19	+	28162770	SKM1	viability	GGAGGACAGCGTGGAGGCAGTGG	PIK3R2	ENSG00000268173	-0.32723700627242747	[43]	[61]	-3	hSpCas9	negative selection	10550122
18166281	18166304	19	+	28162770	SKM1	viability	GCAACGAGAAAGAGATGCAAAGG	PIK3R2	ENSG00000268173	0.4219238848640836	[18]	[44]	4	hSpCas9	negative selection	10550123
18168789	18168812	19	+	28162770	SKM1	viability	GGGCAAGATCAACCGCACGCAGG	PIK3R2	ENSG00000268173	-0.8220016980220055	[19]	[19]	-6	hSpCas9	negative selection	10550124
18155878	18155901	19	-	28162770	SKM1	viability	GAAGCCCTCAGGGCCCGCCATGG	PIK3R2	ENSG00000268173	0.5596326429896246	[70]	[184]	5	hSpCas9	negative selection	10550125
18155966	18155989	19	+	28162770	SKM1	viability	CGTGCTGGTAGTGAGCCGGGCGG	PIK3R2	ENSG00000268173	-2.9215373715729203	[29]	[6]	-9	hSpCas9	negative selection	10550126
18156089	18156112	19	-	28162770	SKM1	viability	GGAACTCCACATAGGTGCCAGGG	PIK3R2	ENSG00000268173	0.007113742774409237	[93]	[166]	0	hSpCas9	negative selection	10550127
18160481	18160504	19	-	28162770	SKM1	viability	AGAACTGCTCGGGCAAGTCGGGG	PIK3R2	ENSG00000268173	0.0663529461490854	[46]	[86]	0	hSpCas9	negative selection	10550128
18156021	18156044	19	+	28162770	SKM1	viability	GAGCGCTGCCCACAGAGCGTGGG	PIK3R2	ENSG00000268173	-0.4500329206350475	[33]	[43]	-4	hSpCas9	negative selection	10719485
18162411	18162434	19	+	28162770	SKM1	viability	GGAGGTGAACGAGAAACTCCGGG	PIK3R2	ENSG00000268173	-2.237039197300849	[7]	[2]	-8	hSpCas9	negative selection	10719486
18162017	18162040	19	+	28162770	SKM1	viability	GGAACACTTGGAAGAGCAGGAGG	PIK3R2	ENSG00000268173	0.41718596585742074	[60]	[143]	4	hSpCas9	negative selection	10719487
18163277	18163300	19	+	28162770	SKM1	viability	GGAGGACAGCGTGGAGGCAGTGG	PIK3R2	ENSG00000268173	-0.32723700627242747	[43]	[61]	-3	hSpCas9	negative selection	10719488
18166281	18166304	19	+	28162770	SKM1	viability	GCAACGAGAAAGAGATGCAAAGG	PIK3R2	ENSG00000268173	0.4219238848640836	[18]	[44]	4	hSpCas9	negative selection	10719489
18168789	18168812	19	+	28162770	SKM1	viability	GGGCAAGATCAACCGCACGCAGG	PIK3R2	ENSG00000268173	-0.8220016980220055	[19]	[19]	-6	hSpCas9	negative selection	10719490
18155878	18155901	19	-	28162770	SKM1	viability	GAAGCCCTCAGGGCCCGCCATGG	PIK3R2	ENSG00000268173	0.5596326429896246	[70]	[184]	5	hSpCas9	negative selection	10719491
18155966	18155989	19	+	28162770	SKM1	viability	CGTGCTGGTAGTGAGCCGGGCGG	PIK3R2	ENSG00000268173	-2.9215373715729203	[29]	[6]	-9	hSpCas9	negative selection	10719492
18156089	18156112	19	-	28162770	SKM1	viability	GGAACTCCACATAGGTGCCAGGG	PIK3R2	ENSG00000268173	0.007113742774409237	[93]	[166]	0	hSpCas9	negative selection	10719493
18160481	18160504	19	-	28162770	SKM1	viability	AGAACTGCTCGGGCAAGTCGGGG	PIK3R2	ENSG00000268173	0.0663529461490854	[46]	[86]	0	hSpCas9	negative selection	10719494
18156021	18156044	19	+	28162770	PL21	viability	GAGCGCTGCCCACAGAGCGTGGG	PIK3R2	ENSG00000268173	-1.5413273719118266	[106]	[15]	-7	hSpCas9	negative selection	10888851
18162411	18162434	19	+	28162770	PL21	viability	GGAGGTGAACGAGAAACTCCGGG	PIK3R2	ENSG00000268173	-0.7384598408465366	[45]	[11]	-5	hSpCas9	negative selection	10888852
18162017	18162040	19	+	28162770	PL21	viability	GGAACACTTGGAAGAGCAGGAGG	PIK3R2	ENSG00000268173	-1.140089297140986	[237]	[46]	-6	hSpCas9	negative selection	10888853
18163277	18163300	19	+	28162770	PL21	viability	GGAGGACAGCGTGGAGGCAGTGG	PIK3R2	ENSG00000268173	-2.3234223415676927	[137]	[11]	-8	hSpCas9	negative selection	10888854
18166281	18166304	19	+	28162770	PL21	viability	GCAACGAGAAAGAGATGCAAAGG	PIK3R2	ENSG00000268173	-0.3692260311808173	[91]	[30]	-3	hSpCas9	negative selection	10888855
18168789	18168812	19	+	28162770	PL21	viability	GGGCAAGATCAACCGCACGCAGG	PIK3R2	ENSG00000268173	-1.232819792786786	[53]	[9]	-7	hSpCas9	negative selection	10888856
18155878	18155901	19	-	28162770	PL21	viability	GAAGCCCTCAGGGCCCGCCATGG	PIK3R2	ENSG00000268173	0.228428658920744	[201]	[102]	2	hSpCas9	negative selection	10888857
18155966	18155989	19	+	28162770	PL21	viability	CGTGCTGGTAGTGAGCCGGGCGG	PIK3R2	ENSG00000268173	-1.9697853869529924	[80]	[8]	-8	hSpCas9	negative selection	10888858
18156089	18156112	19	-	28162770	PL21	viability	GGAACTCCACATAGGTGCCAGGG	PIK3R2	ENSG00000268173	-0.5603196823438222	[226]	[66]	-4	hSpCas9	negative selection	10888859
18160481	18160504	19	-	28162770	PL21	viability	AGAACTGCTCGGGCAAGTCGGGG	PIK3R2	ENSG00000268173	0.5116007103256139	[165]	[102]	4	hSpCas9	negative selection	10888860
18156021	18156044	19	+	28162770	P31FUJ	viability	GAGCGCTGCCCACAGAGCGTGGG	PIK3R2	ENSG00000268173	-0.2328022044143787	[71]	[71]	-2	hSpCas9	negative selection	11058217
18162411	18162434	19	+	28162770	P31FUJ	viability	GGAGGTGAACGAGAAACTCCGGG	PIK3R2	ENSG00000268173	-0.45519462575082636	[27]	[23]	-4	hSpCas9	negative selection	11058218
18162017	18162040	19	+	28162770	P31FUJ	viability	GGAACACTTGGAAGAGCAGGAGG	PIK3R2	ENSG00000268173	0.3614680385330057	[205]	[310]	4	hSpCas9	negative selection	11058219
18163277	18163300	19	+	28162770	P31FUJ	viability	GGAGGACAGCGTGGAGGCAGTGG	PIK3R2	ENSG00000268173	-4.42042920759015	[163]	[8]	-9	hSpCas9	negative selection	11058220
18166281	18166304	19	+	28162770	P31FUJ	viability	GCAACGAGAAAGAGATGCAAAGG	PIK3R2	ENSG00000268173	-0.12215814073038611	[137]	[148]	-1	hSpCas9	negative selection	11058221
18168789	18168812	19	+	28162770	P31FUJ	viability	GGGCAAGATCAACCGCACGCAGG	PIK3R2	ENSG00000268173	-0.6478397036932226	[39]	[29]	-5	hSpCas9	negative selection	11058222
18155878	18155901	19	-	28162770	P31FUJ	viability	GAAGCCCTCAGGGCCCGCCATGG	PIK3R2	ENSG00000268173	1.2123026327238169	[183]	[500]	9	hSpCas9	negative selection	11058223
18155966	18155989	19	+	28162770	P31FUJ	viability	CGTGCTGGTAGTGAGCCGGGCGG	PIK3R2	ENSG00000268173	-0.0025045849925844355	[103]	[121]	0	hSpCas9	negative selection	11058224
18156089	18156112	19	-	28162770	P31FUJ	viability	GGAACTCCACATAGGTGCCAGGG	PIK3R2	ENSG00000268173	0.09300932496021186	[370]	[464]	0	hSpCas9	negative selection	11058225
18160481	18160504	19	-	28162770	P31FUJ	viability	AGAACTGCTCGGGCAAGTCGGGG	PIK3R2	ENSG00000268173	0.6159038174366809	[225]	[406]	7	hSpCas9	negative selection	11058226
18156021	18156044	19	+	28162770	OCIAML5	viability	GAGCGCTGCCCACAGAGCGTGGG	PIK3R2	ENSG00000268173	-1.7589571664725157	[44]	[23]	-7	hSpCas9	negative selection	11227583
18162411	18162434	19	+	28162770	OCIAML5	viability	GGAGGTGAACGAGAAACTCCGGG	PIK3R2	ENSG00000268173	0.782648965054259	[18]	[58]	7	hSpCas9	negative selection	11227584
18162017	18162040	19	+	28162770	OCIAML5	viability	GGAACACTTGGAAGAGCAGGAGG	PIK3R2	ENSG00000268173	0.8373333400501535	[110]	[357]	7	hSpCas9	negative selection	11227585
18163277	18163300	19	+	28162770	OCIAML5	viability	GGAGGACAGCGTGGAGGCAGTGG	PIK3R2	ENSG00000268173	0.0003762407221450381	[35]	[64]	0	hSpCas9	negative selection	11227586
18166281	18166304	19	+	28162770	OCIAML5	viability	GCAACGAGAAAGAGATGCAAAGG	PIK3R2	ENSG00000268173	0.6598324676674359	[53]	[153]	6	hSpCas9	negative selection	11227587
18168789	18168812	19	+	28162770	OCIAML5	viability	GGGCAAGATCAACCGCACGCAGG	PIK3R2	ENSG00000268173	0.7127180479195288	[23]	[70]	6	hSpCas9	negative selection	11227588
18155878	18155901	19	-	28162770	OCIAML5	viability	GAAGCCCTCAGGGCCCGCCATGG	PIK3R2	ENSG00000268173	0.8818261892525862	[140]	[468]	7	hSpCas9	negative selection	11227589
18155966	18155989	19	+	28162770	OCIAML5	viability	CGTGCTGGTAGTGAGCCGGGCGG	PIK3R2	ENSG00000268173	-0.6698632396432478	[51]	[58]	-4	hSpCas9	negative selection	11227590
18156089	18156112	19	-	28162770	OCIAML5	viability	GGAACTCCACATAGGTGCCAGGG	PIK3R2	ENSG00000268173	0.20564892699229048	[146]	[305]	1	hSpCas9	negative selection	11227591
18160481	18160504	19	-	28162770	OCIAML5	viability	AGAACTGCTCGGGCAAGTCGGGG	PIK3R2	ENSG00000268173	0.25299403061060066	[138]	[298]	2	hSpCas9	negative selection	11227592
18156021	18156044	19	+	28162770	EOL1	viability	GAGCGCTGCCCACAGAGCGTGGG	PIK3R2	ENSG00000268173	-1.5202370711023612	[146]	[26]	-7	hSpCas9	negative selection	11396949
18162411	18162434	19	+	28162770	EOL1	viability	GGAGGTGAACGAGAAACTCCGGG	PIK3R2	ENSG00000268173	0.41758778285065157	[26]	[18]	4	hSpCas9	negative selection	11396950
18162017	18162040	19	+	28162770	EOL1	viability	GGAACACTTGGAAGAGCAGGAGG	PIK3R2	ENSG00000268173	0.5061116958298257	[424]	[317]	4	hSpCas9	negative selection	11396951
18163277	18163300	19	+	28162770	EOL1	viability	GGAGGACAGCGTGGAGGCAGTGG	PIK3R2	ENSG00000268173	-2.0248261553594977	[223]	[28]	-8	hSpCas9	negative selection	11396952
18166281	18166304	19	+	28162770	EOL1	viability	GCAACGAGAAAGAGATGCAAAGG	PIK3R2	ENSG00000268173	-0.2587977456340994	[242]	[106]	-2	hSpCas9	negative selection	11396953
18168789	18168812	19	+	28162770	EOL1	viability	GGGCAAGATCAACCGCACGCAGG	PIK3R2	ENSG00000268173	0.9245477715705346	[93]	[93]	7	hSpCas9	negative selection	11396954
18155878	18155901	19	-	28162770	EOL1	viability	GAAGCCCTCAGGGCCCGCCATGG	PIK3R2	ENSG00000268173	0.7498149269325123	[262]	[232]	6	hSpCas9	negative selection	11396955
18155966	18155989	19	+	28162770	EOL1	viability	CGTGCTGGTAGTGAGCCGGGCGG	PIK3R2	ENSG00000268173	-1.8033726829926646	[105]	[15]	-8	hSpCas9	negative selection	11396956
18156089	18156112	19	-	28162770	EOL1	viability	GGAACTCCACATAGGTGCCAGGG	PIK3R2	ENSG00000268173	-0.05106806980250639	[351]	[178]	0	hSpCas9	negative selection	11396957
18160481	18160504	19	-	28162770	EOL1	viability	AGAACTGCTCGGGCAAGTCGGGG	PIK3R2	ENSG00000268173	-0.3226699288004844	[253]	[106]	-2	hSpCas9	negative selection	11396958
18156021	18156044	19	+	28162770	MOLM13	viability	GAGCGCTGCCCACAGAGCGTGGG	PIK3R2	ENSG00000268173	-0.31487990223475204	[159]	[92]	-2	hSpCas9	negative selection	11566315
18162411	18162434	19	+	28162770	MOLM13	viability	GGAGGTGAACGAGAAACTCCGGG	PIK3R2	ENSG00000268173	0.8158126849648859	[21]	[27]	6	hSpCas9	negative selection	11566316
18162017	18162040	19	+	28162770	MOLM13	viability	GGAACACTTGGAAGAGCAGGAGG	PIK3R2	ENSG00000268173	-0.0955399576269361	[265]	[179]	0	hSpCas9	negative selection	11566317
18163277	18163300	19	+	28162770	MOLM13	viability	GGAGGACAGCGTGGAGGCAGTGG	PIK3R2	ENSG00000268173	-1.162161008705115	[194]	[62]	-6	hSpCas9	negative selection	11566318
18166281	18166304	19	+	28162770	MOLM13	viability	GCAACGAGAAAGAGATGCAAAGG	PIK3R2	ENSG00000268173	-0.19107370062035423	[179]	[113]	-1	hSpCas9	negative selection	11566319
18168789	18168812	19	+	28162770	MOLM13	viability	GGGCAAGATCAACCGCACGCAGG	PIK3R2	ENSG00000268173	-1.3960490688793927	[90]	[24]	-6	hSpCas9	negative selection	11566320
18155878	18155901	19	-	28162770	MOLM13	viability	GAAGCCCTCAGGGCCCGCCATGG	PIK3R2	ENSG00000268173	1.0414245350679217	[337]	[502]	7	hSpCas9	negative selection	11566321
18155966	18155989	19	+	28162770	MOLM13	viability	CGTGCTGGTAGTGAGCCGGGCGG	PIK3R2	ENSG00000268173	-1.7397060378637885	[96]	[20]	-7	hSpCas9	negative selection	11566322
18156089	18156112	19	-	28162770	MOLM13	viability	GGAACTCCACATAGGTGCCAGGG	PIK3R2	ENSG00000268173	0.011511086884835375	[412]	[300]	0	hSpCas9	negative selection	11566323
18160481	18160504	19	-	28162770	MOLM13	viability	AGAACTGCTCGGGCAAGTCGGGG	PIK3R2	ENSG00000268173	-0.01157999032926349	[289]	[207]	0	hSpCas9	negative selection	11566324
18156021	18156044	19	+	28162770	HEL	viability	GAGCGCTGCCCACAGAGCGTGGG	PIK3R2	ENSG00000268173	-0.4460704349574992	[133]	[62]	-3	hSpCas9	negative selection	11735681
18162411	18162434	19	+	28162770	HEL	viability	GGAGGTGAACGAGAAACTCCGGG	PIK3R2	ENSG00000268173	-1.1508102905322168	[51]	[14]	-6	hSpCas9	negative selection	11735682
18162017	18162040	19	+	28162770	HEL	viability	GGAACACTTGGAAGAGCAGGAGG	PIK3R2	ENSG00000268173	0.6525198527929424	[293]	[295]	5	hSpCas9	negative selection	11735683
18163277	18163300	19	+	28162770	HEL	viability	GGAGGACAGCGTGGAGGCAGTGG	PIK3R2	ENSG00000268173	-0.42139150541935877	[160]	[76]	-3	hSpCas9	negative selection	11735684
18166281	18166304	19	+	28162770	HEL	viability	GCAACGAGAAAGAGATGCAAAGG	PIK3R2	ENSG00000268173	0.36059560321885836	[151]	[124]	3	hSpCas9	negative selection	11735685
18168789	18168812	19	+	28162770	HEL	viability	GGGCAAGATCAACCGCACGCAGG	PIK3R2	ENSG00000268173	0.8521921976293065	[63]	[73]	7	hSpCas9	negative selection	11735686
18155878	18155901	19	-	28162770	HEL	viability	GAAGCCCTCAGGGCCCGCCATGG	PIK3R2	ENSG00000268173	0.7085766453631032	[256]	[268]	6	hSpCas9	negative selection	11735687
18155966	18155989	19	+	28162770	HEL	viability	CGTGCTGGTAGTGAGCCGGGCGG	PIK3R2	ENSG00000268173	-1.1955100980030309	[117]	[32]	-6	hSpCas9	negative selection	11735688
18156089	18156112	19	-	28162770	HEL	viability	GGAACTCCACATAGGTGCCAGGG	PIK3R2	ENSG00000268173	0.08193019298797777	[384]	[260]	0	hSpCas9	negative selection	11735689
18160481	18160504	19	-	28162770	HEL	viability	AGAACTGCTCGGGCAAGTCGGGG	PIK3R2	ENSG00000268173	0.02862998561968423	[224]	[146]	0	hSpCas9	negative selection	11735690
18156021	18156044	19	+	28162770	MV411	viability	GAGCGCTGCCCACAGAGCGTGGG	PIK3R2	ENSG00000268173	-1.0744905441045869	[89]	[35]	-6	hSpCas9	negative selection	11905047
18162411	18162434	19	+	28162770	MV411	viability	GGAGGTGAACGAGAAACTCCGGG	PIK3R2	ENSG00000268173	1.4538884282502018	[25]	[59]	9	hSpCas9	negative selection	11905048
18162017	18162040	19	+	28162770	MV411	viability	GGAACACTTGGAAGAGCAGGAGG	PIK3R2	ENSG00000268173	0.32760789946675883	[209]	[221]	3	hSpCas9	negative selection	11905049
18163277	18163300	19	+	28162770	MV411	viability	GGAGGACAGCGTGGAGGCAGTGG	PIK3R2	ENSG00000268173	-2.464057355867313	[130]	[19]	-8	hSpCas9	negative selection	11905050
18166281	18166304	19	+	28162770	MV411	viability	GCAACGAGAAAGAGATGCAAAGG	PIK3R2	ENSG00000268173	-1.377053314125018	[110]	[35]	-7	hSpCas9	negative selection	11905051
18168789	18168812	19	+	28162770	MV411	viability	GGGCAAGATCAACCGCACGCAGG	PIK3R2	ENSG00000268173	-1.3375249499383808	[77]	[25]	-7	hSpCas9	negative selection	11905052
18155878	18155901	19	-	28162770	MV411	viability	GAAGCCCTCAGGGCCCGCCATGG	PIK3R2	ENSG00000268173	0.6413517584958651	[257]	[338]	6	hSpCas9	negative selection	11905053
18155966	18155989	19	+	28162770	MV411	viability	CGTGCTGGTAGTGAGCCGGGCGG	PIK3R2	ENSG00000268173	-1.4783874857782306	[42]	[12]	-7	hSpCas9	negative selection	11905054
18156089	18156112	19	-	28162770	MV411	viability	GGAACTCCACATAGGTGCCAGGG	PIK3R2	ENSG00000268173	-0.8300412018949421	[305]	[144]	-5	hSpCas9	negative selection	11905055
18160481	18160504	19	-	28162770	MV411	viability	AGAACTGCTCGGGCAAGTCGGGG	PIK3R2	ENSG00000268173	0.08162865781269471	[174]	[155]	0	hSpCas9	negative selection	11905056
18156021	18156044	19	+	28162770	MONOMAC1	viability	GAGCGCTGCCCACAGAGCGTGGG	PIK3R2	ENSG00000268173	-0.7819993477807099	[53]	[35]	-6	hSpCas9	negative selection	12074413
18162411	18162434	19	+	28162770	MONOMAC1	viability	GGAGGTGAACGAGAAACTCCGGG	PIK3R2	ENSG00000268173	0.564803415745682	[22]	[38]	5	hSpCas9	negative selection	12074414
18162017	18162040	19	+	28162770	MONOMAC1	viability	GGAACACTTGGAAGAGCAGGAGG	PIK3R2	ENSG00000268173	1.0024691449324765	[117]	[270]	8	hSpCas9	negative selection	12074415
18163277	18163300	19	+	28162770	MONOMAC1	viability	GGAGGACAGCGTGGAGGCAGTGG	PIK3R2	ENSG00000268173	-1.4600712528933475	[95]	[39]	-8	hSpCas9	negative selection	12074416
18166281	18166304	19	+	28162770	MONOMAC1	viability	GCAACGAGAAAGAGATGCAAAGG	PIK3R2	ENSG00000268173	0.37000374566434036	[53]	[79]	3	hSpCas9	negative selection	12074417
18168789	18168812	19	+	28162770	MONOMAC1	viability	GGGCAAGATCAACCGCACGCAGG	PIK3R2	ENSG00000268173	0.21800065221928988	[26]	[35]	2	hSpCas9	negative selection	12074418
18155878	18155901	19	-	28162770	MONOMAC1	viability	GAAGCCCTCAGGGCCCGCCATGG	PIK3R2	ENSG00000268173	0.7567401361798007	[110]	[214]	7	hSpCas9	negative selection	12074419
18155966	18155989	19	+	28162770	MONOMAC1	viability	CGTGCTGGTAGTGAGCCGGGCGG	PIK3R2	ENSG00000268173	-2.0383391010404956	[42]	[11]	-8	hSpCas9	negative selection	12074420
18156089	18156112	19	-	28162770	MONOMAC1	viability	GGAACTCCACATAGGTGCCAGGG	PIK3R2	ENSG00000268173	-0.49850083938720063	[174]	[141]	-4	hSpCas9	negative selection	12074421
18160481	18160504	19	-	28162770	MONOMAC1	viability	AGAACTGCTCGGGCAAGTCGGGG	PIK3R2	ENSG00000268173	0.04397125244424126	[109]	[129]	0	hSpCas9	negative selection	12074422
18156021	18156044	19	+	28162770	OCIAML2	viability	GAGCGCTGCCCACAGAGCGTGGG	PIK3R2	ENSG00000268173	-1.7569340103988023	[24]	[40]	-8	hSpCas9	negative selection	12243779
18162411	18162434	19	+	28162770	OCIAML2	viability	GGAGGTGAACGAGAAACTCCGGG	PIK3R2	ENSG00000268173	-1.400240497350763	[9]	[20]	-7	hSpCas9	negative selection	12243780
18162017	18162040	19	+	28162770	OCIAML2	viability	GGAACACTTGGAAGAGCAGGAGG	PIK3R2	ENSG00000268173	0.17322636453256363	[39]	[249]	1	hSpCas9	negative selection	12243781
18163277	18163300	19	+	28162770	OCIAML2	viability	GGAGGACAGCGTGGAGGCAGTGG	PIK3R2	ENSG00000268173	-2.869179201732436	[28]	[21]	-9	hSpCas9	negative selection	12243782
18166281	18166304	19	+	28162770	OCIAML2	viability	GCAACGAGAAAGAGATGCAAAGG	PIK3R2	ENSG00000268173	1.2043648763414676	[21]	[280]	9	hSpCas9	negative selection	12243783
18168789	18168812	19	+	28162770	OCIAML2	viability	GGGCAAGATCAACCGCACGCAGG	PIK3R2	ENSG00000268173	-0.011198206604863925	[9]	[54]	0	hSpCas9	negative selection	12243784
18155878	18155901	19	-	28162770	OCIAML2	viability	GAAGCCCTCAGGGCCCGCCATGG	PIK3R2	ENSG00000268173	0.28706721050813144	[37]	[256]	2	hSpCas9	negative selection	12243785
18155966	18155989	19	+	28162770	OCIAML2	viability	CGTGCTGGTAGTGAGCCGGGCGG	PIK3R2	ENSG00000268173	-1.348639300863551	[16]	[36]	-7	hSpCas9	negative selection	12243786
18156089	18156112	19	-	28162770	OCIAML2	viability	GGAACTCCACATAGGTGCCAGGG	PIK3R2	ENSG00000268173	-0.32026709017836674	[65]	[292]	-3	hSpCas9	negative selection	12243787
18160481	18160504	19	-	28162770	OCIAML2	viability	AGAACTGCTCGGGCAAGTCGGGG	PIK3R2	ENSG00000268173	-0.34409741931322935	[29]	[130]	-3	hSpCas9	negative selection	12243788
18156021	18156044	19	+	28162770	OCIAML3	viability	GAGCGCTGCCCACAGAGCGTGGG	PIK3R2	ENSG00000268173	-1.1789701410453193	[14]	[19]	-7	hSpCas9	negative selection	12413145
18162411	18162434	19	+	28162770	OCIAML3	viability	GGAGGTGAACGAGAAACTCCGGG	PIK3R2	ENSG00000268173	0.7564896067599698	[9]	[50]	6	hSpCas9	negative selection	12413146
18162017	18162040	19	+	28162770	OCIAML3	viability	GGAACACTTGGAAGAGCAGGAGG	PIK3R2	ENSG00000268173	0.13905349938612704	[73]	[245]	1	hSpCas9	negative selection	12413147
18163277	18163300	19	+	28162770	OCIAML3	viability	GGAGGACAGCGTGGAGGCAGTGG	PIK3R2	ENSG00000268173	-2.947644594938864	[45]	[17]	-9	hSpCas9	negative selection	12413148
18166281	18166304	19	+	28162770	OCIAML3	viability	GCAACGAGAAAGAGATGCAAAGG	PIK3R2	ENSG00000268173	0.749946760893198	[25]	[131]	6	hSpCas9	negative selection	12413149
18168789	18168812	19	+	28162770	OCIAML3	viability	GGGCAAGATCAACCGCACGCAGG	PIK3R2	ENSG00000268173	2.0498485494505614	[5]	[74]	9	hSpCas9	negative selection	12413150
18155878	18155901	19	-	28162770	OCIAML3	viability	GAAGCCCTCAGGGCCCGCCATGG	PIK3R2	ENSG00000268173	1.6106827792788256	[40]	[377]	9	hSpCas9	negative selection	12413151
18155966	18155989	19	+	28162770	OCIAML3	viability	CGTGCTGGTAGTGAGCCGGGCGG	PIK3R2	ENSG00000268173	0.10113777814741565	[20]	[67]	1	hSpCas9	negative selection	12413152
18156089	18156112	19	-	28162770	OCIAML3	viability	GGAACTCCACATAGGTGCCAGGG	PIK3R2	ENSG00000268173	-0.22477383065844397	[71]	[185]	-2	hSpCas9	negative selection	12413153
18160481	18160504	19	-	28162770	OCIAML3	viability	AGAACTGCTCGGGCAAGTCGGGG	PIK3R2	ENSG00000268173	-1.079434467494405	[62]	[89]	-6	hSpCas9	negative selection	12413154