Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:5307
• Symbol:PITX1
• Description:paired like homeodomain 1

DataSource: http://genomecrispr.dkfz.de/#!/results/PITX1

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
135031493	135031516	5	-	26472758	Jiyoye	viability	ACTGCAGAGAAGGAGCGCGGCGG	PITX1	ENSG00000069011	-0.37351159008965085	[133]	[77]	-3	hSpCas9	negative selection	121116
135031461	135031484	5	-	26472758	Jiyoye	viability	GGGGCCCGAGGACAGTGGTGCGG	PITX1	ENSG00000069011	-0.39578777143457267	[81]	[46]	-3	hSpCas9	negative selection	121117
135031408	135031431	5	-	26472758	Jiyoye	viability	CAGCCAAGAAGAAGAAGCAGCGG	PITX1	ENSG00000069011	0.09114788805819529	[182]	[146]	0	hSpCas9	negative selection	121118
135031362	135031385	5	-	26472758	Jiyoye	viability	CCAGCAGTTGCAAGAGCTAGAGG	PITX1	ENSG00000069011	0.9523368741690545	[97]	[142]	6	hSpCas9	negative selection	121119
135031493	135031516	5	-	26472758	KBM7	viability	ACTGCAGAGAAGGAGCGCGGCGG	PITX1	ENSG00000069011	0.14332467707547414	[201,124]	[96,70]	1	hSpCas9	negative selection	312234
135031461	135031484	5	-	26472758	KBM7	viability	GGGGCCCGAGGACAGTGGTGCGG	PITX1	ENSG00000069011	-0.4414003123999559	[512,456]	[143,188]	-4	hSpCas9	negative selection	312235
135031408	135031431	5	-	26472758	KBM7	viability	CAGCCAAGAAGAAGAAGCAGCGG	PITX1	ENSG00000069011	-0.19523336091391585	[749,545]	[373,163]	-2	hSpCas9	negative selection	312236
135031362	135031385	5	-	26472758	KBM7	viability	CCAGCAGTTGCAAGAGCTAGAGG	PITX1	ENSG00000069011	0.3105344941578662	[454,501]	[285,277]	3	hSpCas9	negative selection	312237
135031493	135031516	5	-	26472758	Raji	viability	ACTGCAGAGAAGGAGCGCGGCGG	PITX1	ENSG00000069011	0.5527946836959619	[46]	[15]	5	hSpCas9	negative selection	503352
135031461	135031484	5	-	26472758	Raji	viability	GGGGCCCGAGGACAGTGGTGCGG	PITX1	ENSG00000069011	-0.3294803263584227	[221]	[40]	-3	hSpCas9	negative selection	503353
135031408	135031431	5	-	26472758	Raji	viability	CAGCCAAGAAGAAGAAGCAGCGG	PITX1	ENSG00000069011	-0.08737331904864842	[292]	[63]	0	hSpCas9	negative selection	503354
135031362	135031385	5	-	26472758	Raji	viability	CCAGCAGTTGCAAGAGCTAGAGG	PITX1	ENSG00000069011	0.1591660774761458	[300]	[77]	1	hSpCas9	negative selection	503355
135031493	135031516	5	-	26472758	K562	viability	ACTGCAGAGAAGGAGCGCGGCGG	PITX1	ENSG00000069011	0.8251934314241699	[114]	[171]	7	hSpCas9	negative selection	694470
135031461	135031484	5	-	26472758	K562	viability	GGGGCCCGAGGACAGTGGTGCGG	PITX1	ENSG00000069011	-2.456020990474645	[350]	[53]	-8	hSpCas9	negative selection	694471
135031408	135031431	5	-	26472758	K562	viability	CAGCCAAGAAGAAGAAGCAGCGG	PITX1	ENSG00000069011	-0.30530659299816776	[545]	[372]	-2	hSpCas9	negative selection	694472
135031362	135031385	5	-	26472758	K562	viability	CCAGCAGTTGCAAGAGCTAGAGG	PITX1	ENSG00000069011	0.1825534720815874	[404]	[387]	1	hSpCas9	negative selection	694473
135028899	135028922	5	+	26627737	DLD1	viability	CCGGTAGACGCTGTAGGGCGAGG	PITX1	ENSG00000069011	0.37677809634215154	[466]	[333,131,111]	4	hSpCas9	negative selection	826912
135029240	135029263	5	+	26627737	DLD1	viability	GCACGTAGCCACCCTTGCACAGG	PITX1	ENSG00000069011	-0.5227518593659344	[1497]	[291,399,293]	-5	hSpCas9	negative selection	826913
135031496	135031519	5	-	26627737	DLD1	viability	CCTACTGCAGAGAAGGAGCGCGG	PITX1	ENSG00000069011	-0.23944023286485372	[438]	[236,93,29]	-3	hSpCas9	negative selection	826914
135031503	135031526	5	-	26627737	DLD1	viability	CGTCCTGCCTACTGCAGAGAAGG	PITX1	ENSG00000069011	0.3899957142934638	[1155]	[523,343,536]	4	hSpCas9	negative selection	826915
135028899	135028922	5	+	26627737	GBM cells	viability after 5 days	CCGGTAGACGCTGTAGGGCGAGG	PITX1	ENSG00000069011	-0.026124067433092313	[224]	[110,125]	0	hSpCas9	negative selection	909227
135029240	135029263	5	+	26627737	GBM cells	viability after 5 days	GCACGTAGCCACCCTTGCACAGG	PITX1	ENSG00000069011	0.31037591994070224	[302]	[248,153]	5	hSpCas9	negative selection	909228
135031496	135031519	5	-	26627737	GBM cells	viability after 5 days	CCTACTGCAGAGAAGGAGCGCGG	PITX1	ENSG00000069011	-0.8731341784359657	[221]	[52,76]	-8	hSpCas9	negative selection	909229
135031503	135031526	5	-	26627737	GBM cells	viability after 5 days	CGTCCTGCCTACTGCAGAGAAGG	PITX1	ENSG00000069011	0.6209634770589256	[524]	[512,352]	8	hSpCas9	negative selection	909230
135028899	135028922	5	+	26627737	GBM cells	viability after 13 days	CCGGTAGACGCTGTAGGGCGAGG	PITX1	ENSG00000069011	-0.03205457956073593	[224]	[157,87]	0	hSpCas9	negative selection	991542
135029240	135029263	5	+	26627737	GBM cells	viability after 13 days	GCACGTAGCCACCCTTGCACAGG	PITX1	ENSG00000069011	0.6966820126600671	[302]	[357,191]	8	hSpCas9	negative selection	991543
135031496	135031519	5	-	26627737	GBM cells	viability after 13 days	CCTACTGCAGAGAAGGAGCGCGG	PITX1	ENSG00000069011	-0.7459280990345946	[221]	[62,78]	-7	hSpCas9	negative selection	991544
135031503	135031526	5	-	26627737	GBM cells	viability after 13 days	CGTCCTGCCTACTGCAGAGAAGG	PITX1	ENSG00000069011	0.1926387710650439	[524]	[383,277]	2	hSpCas9	negative selection	991545
135028899	135028922	5	+	26627737	GBM cells	viability after 21 days	CCGGTAGACGCTGTAGGGCGAGG	PITX1	ENSG00000069011	-0.7062261056029746	[224]	[64,83]	-6	hSpCas9	negative selection	1073857
135029240	135029263	5	+	26627737	GBM cells	viability after 21 days	GCACGTAGCCACCCTTGCACAGG	PITX1	ENSG00000069011	0.7607783869047753	[302]	[268,287]	7	hSpCas9	negative selection	1073858
135031496	135031519	5	-	26627737	GBM cells	viability after 21 days	CCTACTGCAGAGAAGGAGCGCGG	PITX1	ENSG00000069011	-2.1730152365896256	[221]	[20,31]	-9	hSpCas9	negative selection	1073859
135031503	135031526	5	-	26627737	GBM cells	viability after 21 days	CGTCCTGCCTACTGCAGAGAAGG	PITX1	ENSG00000069011	0.2203056878872114	[524]	[313,348]	2	hSpCas9	negative selection	1073860
135028899	135028922	5	+	26627737	RPE1	viability after 9 days	CCGGTAGACGCTGTAGGGCGAGG	PITX1	ENSG00000069011	1.222215582571743	[700]	[580,422]	7	hSpCas9	negative selection	1156172
135029240	135029263	5	+	26627737	RPE1	viability after 9 days	GCACGTAGCCACCCTTGCACAGG	PITX1	ENSG00000069011	0.829336582955267	[1271]	[597,848]	5	hSpCas9	negative selection	1156173
135031496	135031519	5	-	26627737	RPE1	viability after 9 days	CCTACTGCAGAGAAGGAGCGCGG	PITX1	ENSG00000069011	-1.3617825482304768	[1144]	[128,152]	-7	hSpCas9	negative selection	1156174
135031503	135031526	5	-	26627737	RPE1	viability after 9 days	CGTCCTGCCTACTGCAGAGAAGG	PITX1	ENSG00000069011	-0.3058986697750241	[2263]	[692,418]	-2	hSpCas9	negative selection	1156175
135028899	135028922	5	+	26627737	RPE1	viability after 12 days	CCGGTAGACGCTGTAGGGCGAGG	PITX1	ENSG00000069011	1.4830130584145789	[700]	[677,365]	7	hSpCas9	negative selection	1238487
135029240	135029263	5	+	26627737	RPE1	viability after 12 days	GCACGTAGCCACCCTTGCACAGG	PITX1	ENSG00000069011	0.6348646841081347	[1271]	[433,632]	4	hSpCas9	negative selection	1238488
135031496	135031519	5	-	26627737	RPE1	viability after 12 days	CCTACTGCAGAGAAGGAGCGCGG	PITX1	ENSG00000069011	-0.9849125521184332	[1144]	[118,193]	-6	hSpCas9	negative selection	1238489
135031503	135031526	5	-	26627737	RPE1	viability after 12 days	CGTCCTGCCTACTGCAGAGAAGG	PITX1	ENSG00000069011	-0.2273685427607317	[2263]	[555,480]	-1	hSpCas9	negative selection	1238490
135028899	135028922	5	+	26627737	RPE1	viability after 15 days	CCGGTAGACGCTGTAGGGCGAGG	PITX1	ENSG00000069011	1.8706305367134681	[700]	[1109,353]	8	hSpCas9	negative selection	1320802
135029240	135029263	5	+	26627737	RPE1	viability after 15 days	GCACGTAGCCACCCTTGCACAGG	PITX1	ENSG00000069011	0.36496747398388196	[1271]	[412,511]	2	hSpCas9	negative selection	1320803
135031496	135031519	5	-	26627737	RPE1	viability after 15 days	CCTACTGCAGAGAAGGAGCGCGG	PITX1	ENSG00000069011	-1.117085305633129	[1144]	[102,193]	-6	hSpCas9	negative selection	1320804
135031503	135031526	5	-	26627737	RPE1	viability after 15 days	CGTCCTGCCTACTGCAGAGAAGG	PITX1	ENSG00000069011	-0.04547468795758669	[2263]	[841,406]	0	hSpCas9	negative selection	1320805
135028899	135028922	5	+	26627737	RPE1	viability after 18 days	CCGGTAGACGCTGTAGGGCGAGG	PITX1	ENSG00000069011	1.8392177448374811	[700]	[819,523]	8	hSpCas9	negative selection	1403117
135029240	135029263	5	+	26627737	RPE1	viability after 18 days	GCACGTAGCCACCCTTGCACAGG	PITX1	ENSG00000069011	0.4083552136234736	[1271]	[253,670]	2	hSpCas9	negative selection	1403118
135031496	135031519	5	-	26627737	RPE1	viability after 18 days	CCTACTGCAGAGAAGGAGCGCGG	PITX1	ENSG00000069011	-0.224171693286501	[1144]	[279,247]	-1	hSpCas9	negative selection	1403119
135031503	135031526	5	-	26627737	RPE1	viability after 18 days	CGTCCTGCCTACTGCAGAGAAGG	PITX1	ENSG00000069011	-0.3460496187822284	[2263]	[485,474]	-2	hSpCas9	negative selection	1403120
135028899	135028922	5	+	26627737	HeLa	viability after 8 days	CCGGTAGACGCTGTAGGGCGAGG	PITX1	ENSG00000069011	-0.08823529867422353	[495]	[263,251,112]	-1	hSpCas9	negative selection	1485432
135029240	135029263	5	+	26627737	HeLa	viability after 8 days	GCACGTAGCCACCCTTGCACAGG	PITX1	ENSG00000069011	-0.09278347815631391	[472]	[170,281,125]	-1	hSpCas9	negative selection	1485433
135031496	135031519	5	-	26627737	HeLa	viability after 8 days	CCTACTGCAGAGAAGGAGCGCGG	PITX1	ENSG00000069011	-0.5633282677356422	[353]	[131,84,101]	-5	hSpCas9	negative selection	1485434
135031503	135031526	5	-	26627737	HeLa	viability after 8 days	CGTCCTGCCTACTGCAGAGAAGG	PITX1	ENSG00000069011	0.2993628825026854	[741]	[377,386,420]	3	hSpCas9	negative selection	1485435
135028899	135028922	5	+	26627737	HeLa	viability after 12 days	CCGGTAGACGCTGTAGGGCGAGG	PITX1	ENSG00000069011	-0.7558104146279297	[495]	[30,135,192]	-6	hSpCas9	negative selection	1567747
135029240	135029263	5	+	26627737	HeLa	viability after 12 days	GCACGTAGCCACCCTTGCACAGG	PITX1	ENSG00000069011	-0.6966843085556245	[472]	[100,188,63]	-6	hSpCas9	negative selection	1567748
135031496	135031519	5	-	26627737	HeLa	viability after 12 days	CCTACTGCAGAGAAGGAGCGCGG	PITX1	ENSG00000069011	-0.4428557906999284	[353]	[44,60,219]	-4	hSpCas9	negative selection	1567749
135031503	135031526	5	-	26627737	HeLa	viability after 12 days	CGTCCTGCCTACTGCAGAGAAGG	PITX1	ENSG00000069011	0.011164259493370632	[741]	[460,341,124]	0	hSpCas9	negative selection	1567750
135028899	135028922	5	+	26627737	HeLa	viability after 15 days	CCGGTAGACGCTGTAGGGCGAGG	PITX1	ENSG00000069011	0.5531328369713286	[495]	[329,133,434]	4	hSpCas9	negative selection	1650062
135029240	135029263	5	+	26627737	HeLa	viability after 15 days	GCACGTAGCCACCCTTGCACAGG	PITX1	ENSG00000069011	-0.438971081857431	[472]	[130,71,229]	-4	hSpCas9	negative selection	1650063
135031496	135031519	5	-	26627737	HeLa	viability after 15 days	CCTACTGCAGAGAAGGAGCGCGG	PITX1	ENSG00000069011	-0.6082308185768941	[353]	[156,28,96]	-5	hSpCas9	negative selection	1650064
135031503	135031526	5	-	26627737	HeLa	viability after 15 days	CGTCCTGCCTACTGCAGAGAAGG	PITX1	ENSG00000069011	-0.04998159312258621	[741]	[361,370,128]	0	hSpCas9	negative selection	1650065
135028899	135028922	5	+	26627737	HeLa	viability after 18 days	CCGGTAGACGCTGTAGGGCGAGG	PITX1	ENSG00000069011	0.5441335376653611	[495]	[220,106,434]	4	hSpCas9	negative selection	1732377
135029240	135029263	5	+	26627737	HeLa	viability after 18 days	GCACGTAGCCACCCTTGCACAGG	PITX1	ENSG00000069011	-0.44730277939858254	[472]	[89,54,229]	-4	hSpCas9	negative selection	1732378
135031496	135031519	5	-	26627737	HeLa	viability after 18 days	CCTACTGCAGAGAAGGAGCGCGG	PITX1	ENSG00000069011	-0.5984739650815032	[353]	[104,25,96]	-5	hSpCas9	negative selection	1732379
135031503	135031526	5	-	26627737	HeLa	viability after 18 days	CGTCCTGCCTACTGCAGAGAAGG	PITX1	ENSG00000069011	-0.010487865710528732	[741]	[261,302,128]	0	hSpCas9	negative selection	1732380
135028899	135028922	5	+	26627737	HCT116	viability after 6 days	CCGGTAGACGCTGTAGGGCGAGG	PITX1	ENSG00000069011	0.4608942526099542	[406]	[89,86]	2	hSpCas9	negative selection	1814692
135029240	135029263	5	+	26627737	HCT116	viability after 6 days	GCACGTAGCCACCCTTGCACAGG	PITX1	ENSG00000069011	0.658317003192006	[1402]	[554,233]	3	hSpCas9	negative selection	1814693
135031496	135031519	5	-	26627737	HCT116	viability after 6 days	CCTACTGCAGAGAAGGAGCGCGG	PITX1	ENSG00000069011	1.354415141543039	[194]	[176,23]	7	hSpCas9	negative selection	1814694
135031503	135031526	5	-	26627737	HCT116	viability after 6 days	CGTCCTGCCTACTGCAGAGAAGG	PITX1	ENSG00000069011	1.3586767525122017	[1070]	[541,370]	7	hSpCas9	negative selection	1814695
135028899	135028922	5	+	26627737	HCT116	viability after 8 days	CCGGTAGACGCTGTAGGGCGAGG	PITX1	ENSG00000069011	0.5637059839770515	[239]	[177,204,202]	5	hSpCas9	negative selection	1897007
135029240	135029263	5	+	26627737	HCT116	viability after 8 days	GCACGTAGCCACCCTTGCACAGG	PITX1	ENSG00000069011	-0.2479874994326935	[553]	[201,212,353]	-3	hSpCas9	negative selection	1897008
135031496	135031519	5	-	26627737	HCT116	viability after 8 days	CCTACTGCAGAGAAGGAGCGCGG	PITX1	ENSG00000069011	0.28162615626612997	[180]	[73,178,109]	3	hSpCas9	negative selection	1897009
135031503	135031526	5	-	26627737	HCT116	viability after 8 days	CGTCCTGCCTACTGCAGAGAAGG	PITX1	ENSG00000069011	-0.5143280617275401	[962]	[391,359,362]	-6	hSpCas9	negative selection	1897010
135028899	135028922	5	+	26627737	HCT116	viability after 9 days	CCGGTAGACGCTGTAGGGCGAGG	PITX1	ENSG00000069011	0.31378664754497554	[406]	[119,146]	2	hSpCas9	negative selection	1979322
135029240	135029263	5	+	26627737	HCT116	viability after 9 days	GCACGTAGCCACCCTTGCACAGG	PITX1	ENSG00000069011	-0.5380822268431762	[1402]	[257,257]	-4	hSpCas9	negative selection	1979323
135031496	135031519	5	-	26627737	HCT116	viability after 9 days	CCTACTGCAGAGAAGGAGCGCGG	PITX1	ENSG00000069011	0.4530703420128628	[194]	[39,95]	3	hSpCas9	negative selection	1979324
135031503	135031526	5	-	26627737	HCT116	viability after 9 days	CGTCCTGCCTACTGCAGAGAAGG	PITX1	ENSG00000069011	0.7805143423607306	[1070]	[550,443]	5	hSpCas9	negative selection	1979325
135028899	135028922	5	+	26627737	HCT116	viability after 12 days	CCGGTAGACGCTGTAGGGCGAGG	PITX1	ENSG00000069011	0.31593197385536254	[239]	[227,124,110]	3	hSpCas9	negative selection	2061637
135029240	135029263	5	+	26627737	HCT116	viability after 12 days	GCACGTAGCCACCCTTGCACAGG	PITX1	ENSG00000069011	-0.17358822290023423	[553]	[277,271,222]	-2	hSpCas9	negative selection	2061638
135031496	135031519	5	-	26627737	HCT116	viability after 12 days	CCTACTGCAGAGAAGGAGCGCGG	PITX1	ENSG00000069011	0.05859318313772033	[180]	[49,160,91]	0	hSpCas9	negative selection	2061639
135031503	135031526	5	-	26627737	HCT116	viability after 12 days	CGTCCTGCCTACTGCAGAGAAGG	PITX1	ENSG00000069011	-0.14934265627261012	[962]	[469,466,430]	-1	hSpCas9	negative selection	2061640
135028899	135028922	5	+	26627737	HCT116	viability after 15 days	CCGGTAGACGCTGTAGGGCGAGG	PITX1	ENSG00000069011	0.6558424939619367	[239]	[276,267,114]	6	hSpCas9	negative selection	2143952
135029240	135029263	5	+	26627737	HCT116	viability after 15 days	GCACGTAGCCACCCTTGCACAGG	PITX1	ENSG00000069011	-0.263098493832317	[553]	[390,180,238]	-3	hSpCas9	negative selection	2143953
135031496	135031519	5	-	26627737	HCT116	viability after 15 days	CCTACTGCAGAGAAGGAGCGCGG	PITX1	ENSG00000069011	-0.3719439255045759	[180]	[73,68,96]	-4	hSpCas9	negative selection	2143954
135031503	135031526	5	-	26627737	HCT116	viability after 15 days	CGTCCTGCCTACTGCAGAGAAGG	PITX1	ENSG00000069011	-0.03582218362988532	[962]	[605,518,501]	0	hSpCas9	negative selection	2143955
135028899	135028922	5	+	26627737	HCT116	viability after 18 days	CCGGTAGACGCTGTAGGGCGAGG	PITX1	ENSG00000069011	0.376192280436913	[239]	[200,187,55]	3	hSpCas9	negative selection	2226267
135029240	135029263	5	+	26627737	HCT116	viability after 18 days	GCACGTAGCCACCCTTGCACAGG	PITX1	ENSG00000069011	-0.7011601024492503	[553]	[170,163,158]	-6	hSpCas9	negative selection	2226268
135031496	135031519	5	-	26627737	HCT116	viability after 18 days	CCTACTGCAGAGAAGGAGCGCGG	PITX1	ENSG00000069011	0.4485979112987769	[180]	[100,171,79]	4	hSpCas9	negative selection	2226269
135031503	135031526	5	-	26627737	HCT116	viability after 18 days	CGTCCTGCCTACTGCAGAGAAGG	PITX1	ENSG00000069011	-0.37253257586638266	[962]	[371,258,458]	-3	hSpCas9	negative selection	2226270
135031451	135031474	5	-	24336569	HL60	viability	GACAGTGGTGCGGGAGGCACGGG	PITX1	ENSG00000069011	-0.29778721780660633	[2035]	[3504]	-3	hSpCas9	negative selection	2284290
135031456	135031479	5	+	24336569	HL60	viability	GCCTCCCGCACCACTGTCCTCGG	PITX1	ENSG00000069011	0.10805638088865288	[779]	[1778]	1	hSpCas9	negative selection	2284291
135031492	135031515	5	-	24336569	HL60	viability	CTGCAGAGAAGGAGCGCGGCGGG	PITX1	ENSG00000069011	-0.1586319611513563	[719]	[1364]	-1	hSpCas9	negative selection	2284292
135031451	135031474	5	-	24336569	KBM7	viability	GACAGTGGTGCGGGAGGCACGGG	PITX1	ENSG00000069011	-0.10531135971535877	[1633]	[4142]	-1	hSpCas9	negative selection	2351467
135031456	135031479	5	+	24336569	KBM7	viability	GCCTCCCGCACCACTGTCCTCGG	PITX1	ENSG00000069011	0.47102935010083136	[514]	[1946]	4	hSpCas9	negative selection	2351468
135031492	135031515	5	-	24336569	KBM7	viability	CTGCAGAGAAGGAGCGCGGCGGG	PITX1	ENSG00000069011	0.9156993017260187	[508]	[2618]	7	hSpCas9	negative selection	2351469
135033118	135033141	5	-	25494202	A375	resistance to PLX-4720 (puromycin)	GGAACGCCGATCAAGGGATCCGG	PITX1	ENSG00000069011	0.7767235956046181	[21,90]	[5,37]	3	dCas9-VP64	positive selection	2419483
135033139	135033162	5	-	25494202	A375	resistance to PLX-4720 (puromycin)	GGACTCCCAGCAAGGCCAGCCGG	PITX1	ENSG00000069011	1.3431377770539	[14,63]	[4,40]	5	dCas9-VP64	positive selection	2419484
135033164	135033187	5	-	25494202	A375	resistance to PLX-4720 (puromycin)	GGCGAGCGGGCCAACAGGCGCGG	PITX1	ENSG00000069011	-0.8851939744443764	[23,17]	[2,1]	-5	dCas9-VP64	positive selection	2419485
135033118	135033141	5	-	25494202	A375	resistance to PLX-4720 (zeocin)	GGAACGCCGATCAAGGGATCCGG	PITX1	ENSG00000069011	-1.1049809911565696	[188,105]	[15,27]	-9	dCas9-VP64	positive selection	2514738
135033139	135033162	5	-	25494202	A375	resistance to PLX-4720 (zeocin)	GGACTCCCAGCAAGGCCAGCCGG	PITX1	ENSG00000069011	-0.7320047493338836	[96,51]	[16,10]	-7	dCas9-VP64	positive selection	2514739
135033164	135033187	5	-	25494202	A375	resistance to PLX-4720 (zeocin)	GGCGAGCGGGCCAACAGGCGCGG	PITX1	ENSG00000069011	-0.4155361477383821	[43,16]	[10,3]	-4	dCas9-VP64	positive selection	2514740
135031456	135031479	5	+	27260157	DLD1	viability	GCCTCCCGCACCACTGTCCTCGG	PITX1	ENSG00000069011	0.662160780338389	[]	[]	8	hSpCas9	negative selection	2574258
135029240	135029263	5	+	27260157	DLD1	viability	GCACGTAGCCACCCTTGCACAGG	PITX1	ENSG00000069011	0.169930339696123	[]	[]	3	hSpCas9	negative selection	2574325
135031303	135031326	5	-	27260157	DLD1	viability	TGAGGGAGGAGATCGCCGTGTGG	PITX1	ENSG00000069011	-0.0431037993924273	[]	[]	0	hSpCas9	negative selection	2574458
135029264	135029287	5	-	27260157	DLD1	viability	GCGCGAGCGTAACCAGCAGCTGG	PITX1	ENSG00000069011	-0.301630786118284	[]	[]	-2	hSpCas9	negative selection	2580701
135029227	135029250	5	-	27260157	DLD1	viability	GGCTACGTGCCGCAGTTCAGCGG	PITX1	ENSG00000069011	0.0114833249549007	[]	[]	0	hSpCas9	negative selection	2585124
135031451	135031474	5	-	27260157	DLD1	viability	GACAGTGGTGCGGGAGGCACGGG	PITX1	ENSG00000069011	-0.448310544862892	[]	[]	-4	hSpCas9	negative selection	2613663
135031492	135031515	5	-	27260157	DLD1	viability	CTGCAGAGAAGGAGCGCGGCGGG	PITX1	ENSG00000069011	0.375921049977493	[]	[]	4	hSpCas9	negative selection	2617273
135029207	135029230	5	-	27260157	DLD1	viability	CGGCCTAGTGCAGCCCTACGAGG	PITX1	ENSG00000069011	0.518372096732431	[]	[]	8	hSpCas9	negative selection	2617460
135029218	135029241	5	+	27260157	DLD1	viability	TGCACTAGGCCGCTGAACTGCGG	PITX1	ENSG00000069011	-0.0443107527964025	[]	[]	0	hSpCas9	negative selection	2618151
135031362	135031385	5	+	27260157	DLD1	viability	CCTCTAGCTCTTGCAACTGCTGG	PITX1	ENSG00000069011	-0.0168224804162112	[]	[]	0	hSpCas9	negative selection	2646523
135031456	135031479	5	+	27260157	HT1080	viability	GCCTCCCGCACCACTGTCCTCGG	PITX1	ENSG00000069011	-0.0255011919372244	[]	[]	0	hSpCas9	negative selection	2650388
135029240	135029263	5	+	27260157	HT1080	viability	GCACGTAGCCACCCTTGCACAGG	PITX1	ENSG00000069011	-0.143882107696868	[]	[]	0	hSpCas9	negative selection	2650455
135031303	135031326	5	-	27260157	HT1080	viability	TGAGGGAGGAGATCGCCGTGTGG	PITX1	ENSG00000069011	-0.143458271090239	[]	[]	0	hSpCas9	negative selection	2650588
135029264	135029287	5	-	27260157	HT1080	viability	GCGCGAGCGTAACCAGCAGCTGG	PITX1	ENSG00000069011	-0.282091516140993	[]	[]	-7	hSpCas9	negative selection	2656831
135029227	135029250	5	-	27260157	HT1080	viability	GGCTACGTGCCGCAGTTCAGCGG	PITX1	ENSG00000069011	0.809974572091786	[]	[]	7	hSpCas9	negative selection	2661254
135031451	135031474	5	-	27260157	HT1080	viability	GACAGTGGTGCGGGAGGCACGGG	PITX1	ENSG00000069011	-0.819640998893878	[]	[]	-8	hSpCas9	negative selection	2689793
135031492	135031515	5	-	27260157	HT1080	viability	CTGCAGAGAAGGAGCGCGGCGGG	PITX1	ENSG00000069011	-0.0956482793422426	[]	[]	0	hSpCas9	negative selection	2693403
135029207	135029230	5	-	27260157	HT1080	viability	CGGCCTAGTGCAGCCCTACGAGG	PITX1	ENSG00000069011	0.651702463148868	[]	[]	5	hSpCas9	negative selection	2693590
135029218	135029241	5	+	27260157	HT1080	viability	TGCACTAGGCCGCTGAACTGCGG	PITX1	ENSG00000069011	-0.243580602466331	[]	[]	0	hSpCas9	negative selection	2694281
135031362	135031385	5	+	27260157	HT1080	viability	CCTCTAGCTCTTGCAACTGCTGG	PITX1	ENSG00000069011	-1.02647838742452	[]	[]	-8	hSpCas9	negative selection	2722653
135031456	135031479	5	+	27260157	MKN45	viability	GCCTCCCGCACCACTGTCCTCGG	PITX1	ENSG00000069011	0.329772321832853	[]	[]	6	hSpCas9	negative selection	2726518
135029240	135029263	5	+	27260157	MKN45	viability	GCACGTAGCCACCCTTGCACAGG	PITX1	ENSG00000069011	-0.197570280654802	[]	[]	0	hSpCas9	negative selection	2726585
135031303	135031326	5	-	27260157	MKN45	viability	TGAGGGAGGAGATCGCCGTGTGG	PITX1	ENSG00000069011	-0.95542919289864	[]	[]	-7	hSpCas9	negative selection	2726718
135029264	135029287	5	-	27260157	MKN45	viability	GCGCGAGCGTAACCAGCAGCTGG	PITX1	ENSG00000069011	0.277292893259078	[]	[]	5	hSpCas9	negative selection	2732961
135029227	135029250	5	-	27260157	MKN45	viability	GGCTACGTGCCGCAGTTCAGCGG	PITX1	ENSG00000069011	-0.324271909182701	[]	[]	-1	hSpCas9	negative selection	2737384
135031451	135031474	5	-	27260157	MKN45	viability	GACAGTGGTGCGGGAGGCACGGG	PITX1	ENSG00000069011	-0.378578193650008	[]	[]	-1	hSpCas9	negative selection	2765923
135031492	135031515	5	-	27260157	MKN45	viability	CTGCAGAGAAGGAGCGCGGCGGG	PITX1	ENSG00000069011	0.633813888562244	[]	[]	7	hSpCas9	negative selection	2769533
135029207	135029230	5	-	27260157	MKN45	viability	CGGCCTAGTGCAGCCCTACGAGG	PITX1	ENSG00000069011	1.03751841744537	[]	[]	8	hSpCas9	negative selection	2769720
135029218	135029241	5	+	27260157	MKN45	viability	TGCACTAGGCCGCTGAACTGCGG	PITX1	ENSG00000069011	-0.582465930469849	[]	[]	-6	hSpCas9	negative selection	2770411
135031362	135031385	5	+	27260157	MKN45	viability	CCTCTAGCTCTTGCAACTGCTGG	PITX1	ENSG00000069011	-0.627265067766529	[]	[]	-6	hSpCas9	negative selection	2798783
135031456	135031479	5	+	27260157	RKO	viability	GCCTCCCGCACCACTGTCCTCGG	PITX1	ENSG00000069011	0.263247853224099	[]	[]	1	hSpCas9	negative selection	2802648
135029240	135029263	5	+	27260157	RKO	viability	GCACGTAGCCACCCTTGCACAGG	PITX1	ENSG00000069011	-0.480409434191264	[]	[]	-6	hSpCas9	negative selection	2802715
135031303	135031326	5	-	27260157	RKO	viability	TGAGGGAGGAGATCGCCGTGTGG	PITX1	ENSG00000069011	-0.0534927850693893	[]	[]	0	hSpCas9	negative selection	2802848
135029264	135029287	5	-	27260157	RKO	viability	GCGCGAGCGTAACCAGCAGCTGG	PITX1	ENSG00000069011	0.306268440066533	[]	[]	1	hSpCas9	negative selection	2809091
135029227	135029250	5	-	27260157	RKO	viability	GGCTACGTGCCGCAGTTCAGCGG	PITX1	ENSG00000069011	0.96778813484341	[]	[]	8	hSpCas9	negative selection	2813514
135031451	135031474	5	-	27260157	RKO	viability	GACAGTGGTGCGGGAGGCACGGG	PITX1	ENSG00000069011	-0.892597610974446	[]	[]	-8	hSpCas9	negative selection	2842053
135031492	135031515	5	-	27260157	RKO	viability	CTGCAGAGAAGGAGCGCGGCGGG	PITX1	ENSG00000069011	0.141336208700785	[]	[]	0	hSpCas9	negative selection	2845663
135029207	135029230	5	-	27260157	RKO	viability	CGGCCTAGTGCAGCCCTACGAGG	PITX1	ENSG00000069011	-0.0970040205935279	[]	[]	0	hSpCas9	negative selection	2845850
135029218	135029241	5	+	27260157	RKO	viability	TGCACTAGGCCGCTGAACTGCGG	PITX1	ENSG00000069011	0.146261463609953	[]	[]	0	hSpCas9	negative selection	2846541
135031362	135031385	5	+	27260157	RKO	viability	CCTCTAGCTCTTGCAACTGCTGG	PITX1	ENSG00000069011	-0.814140867136807	[]	[]	-7	hSpCas9	negative selection	2874913
135031456	135031479	5	+	27260157	SF268	viability	GCCTCCCGCACCACTGTCCTCGG	PITX1	ENSG00000069011	0.569046314123233	[]	[]	8	hSpCas9	negative selection	2878778
135029240	135029263	5	+	27260157	SF268	viability	GCACGTAGCCACCCTTGCACAGG	PITX1	ENSG00000069011	-0.536952264108592	[]	[]	-4	hSpCas9	negative selection	2878845
135031303	135031326	5	-	27260157	SF268	viability	TGAGGGAGGAGATCGCCGTGTGG	PITX1	ENSG00000069011	0.223585446094598	[]	[]	3	hSpCas9	negative selection	2878978
135029264	135029287	5	-	27260157	SF268	viability	GCGCGAGCGTAACCAGCAGCTGG	PITX1	ENSG00000069011	-0.187447289746831	[]	[]	-1	hSpCas9	negative selection	2885221
135029227	135029250	5	-	27260157	SF268	viability	GGCTACGTGCCGCAGTTCAGCGG	PITX1	ENSG00000069011	0.585976770481974	[]	[]	8	hSpCas9	negative selection	2889644
135031451	135031474	5	-	27260157	SF268	viability	GACAGTGGTGCGGGAGGCACGGG	PITX1	ENSG00000069011	-0.579676606176608	[]	[]	-4	hSpCas9	negative selection	2918183
135031492	135031515	5	-	27260157	SF268	viability	CTGCAGAGAAGGAGCGCGGCGGG	PITX1	ENSG00000069011	0.507628003723008	[]	[]	7	hSpCas9	negative selection	2921793
135029207	135029230	5	-	27260157	SF268	viability	CGGCCTAGTGCAGCCCTACGAGG	PITX1	ENSG00000069011	0.684896659888366	[]	[]	8	hSpCas9	negative selection	2921980
135029218	135029241	5	+	27260157	SF268	viability	TGCACTAGGCCGCTGAACTGCGG	PITX1	ENSG00000069011	-0.324081549840065	[]	[]	-3	hSpCas9	negative selection	2922671
135031362	135031385	5	+	27260157	SF268	viability	CCTCTAGCTCTTGCAACTGCTGG	PITX1	ENSG00000069011	-0.907066849643842	[]	[]	-6	hSpCas9	negative selection	2951043
135031493	135031516	5	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	ACTGCAGAGAAGGAGCGCGGCGG	PITX1	ENSG00000069011	-0.10609535617104249	[2,2]	[1,1]	-1	hSpCas9	positive selection	3011518
135031408	135031431	5	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CAGCCAAGAAGAAGAAGCAGCGG	PITX1	ENSG00000069011	-0.8133276560917119	[3,3]	[1,0]	-8	hSpCas9	positive selection	3011519
135031496	135031519	5	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CCTACTGCAGAGAAGGAGCGCGG	PITX1	ENSG00000069011	-0.05810590370251753	[4,4]	[4,2]	-1	hSpCas9	positive selection	3011520
135031320	135031343	5	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CTACCCCGACATGAGCATGAGGG	PITX1	ENSG00000069011	-0.23985684248900108	[3,3]	[2,2]	-3	hSpCas9	positive selection	3011521
135031493	135031516	5	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	ACTGCAGAGAAGGAGCGCGGCGG	PITX1	ENSG00000069011	-0.20528728277191116	[2,2]	[2,0]	-3	hSpCas9	positive selection	3079376
135031408	135031431	5	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CAGCCAAGAAGAAGAAGCAGCGG	PITX1	ENSG00000069011	0.5143630331746678	[3,3]	[3,4]	8	hSpCas9	positive selection	3079377
135031496	135031519	5	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CCTACTGCAGAGAAGGAGCGCGG	PITX1	ENSG00000069011	0.17383724489652305	[4,4]	[3,2]	3	hSpCas9	positive selection	3079378
135031320	135031343	5	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CTACCCCGACATGAGCATGAGGG	PITX1	ENSG00000069011	0.573771351532386	[3,3]	[3,3]	8	hSpCas9	positive selection	3079379
135031265	135031288		+	24336571	A375	resistance to PLX after 7 days	CCCTTGCTCACCCGCACGCGCGG	PITX1	ENSG00000069011	0.07435011642401873	[10,8]	[9,10]	2	hSpCas9	positive selection	3135780
135028836	135028859		+	24336571	A375	resistance to PLX after 7 days	GCCAAACGACGAGTGCTGTTTGG	PITX1	ENSG00000069011	0.3981635652544997	[16,13]	[19,20]	8	hSpCas9	positive selection	3135781
135029264	135029287		-	24336571	A375	resistance to PLX after 7 days	GCGCGAGCGTAACCAGCAGCTGG	PITX1	ENSG00000069011	-0.1935537176203527	[11,13]	[11,9]	-6	hSpCas9	positive selection	3135782
135031321	135031344		-	24336571	A375	resistance to PLX after 7 days	GCTACCCCGACATGAGCATGAGG	PITX1	ENSG00000069011	-0.004359570347698738	[12,18]	[15,14]	0	hSpCas9	positive selection	3135784
135031265	135031288		+	24336571	A375	resistance to PLX after 14 days	CCCTTGCTCACCCGCACGCGCGG	PITX1	ENSG00000069011	0.20739357245596307	[9,11]	[5,4]	2	hSpCas9	positive selection	3193573
135028836	135028859		+	24336571	A375	resistance to PLX after 14 days	GCCAAACGACGAGTGCTGTTTGG	PITX1	ENSG00000069011	0.8369580579687727	[18,17]	[16,13]	7	hSpCas9	positive selection	3193574
135029264	135029287		-	24336571	A375	resistance to PLX after 14 days	GCGCGAGCGTAACCAGCAGCTGG	PITX1	ENSG00000069011	0.19005426213429488	[7,9]	[4,3]	2	hSpCas9	positive selection	3193575
135031321	135031344		-	24336571	A375	resistance to PLX after 14 days	GCTACCCCGACATGAGCATGAGG	PITX1	ENSG00000069011	-0.991913870760637	[13,18]	[3,2]	-9	hSpCas9	positive selection	3193577
135031265	135031288		+	24336571	A375	viability after 7 days	CCCTTGCTCACCCGCACGCGCGG	PITX1	ENSG00000069011	0.15425576155663662	[8]	[10,8]	2	hSpCas9	negative selection	3251366
135028836	135028859		+	24336571	A375	viability after 7 days	GCCAAACGACGAGTGCTGTTTGG	PITX1	ENSG00000069011	0.36146257349472377	[12]	[16,13]	5	hSpCas9	negative selection	3251367
135029264	135029287		-	24336571	A375	viability after 7 days	GCGCGAGCGTAACCAGCAGCTGG	PITX1	ENSG00000069011	0.2810533665849132	[10]	[11,13]	4	hSpCas9	negative selection	3251368
135031321	135031344		-	24336571	A375	viability after 7 days	GCTACCCCGACATGAGCATGAGG	PITX1	ENSG00000069011	0.0851259739628977	[15]	[12,18]	1	hSpCas9	negative selection	3251370
135031265	135031288		+	24336571	A375	viability after 14 days	CCCTTGCTCACCCGCACGCGCGG	PITX1	ENSG00000069011	0.2587660108459737	[8]	[9,11]	3	hSpCas9	negative selection	3309159
135028836	135028859		+	24336571	A375	viability after 14 days	GCCAAACGACGAGTGCTGTTTGG	PITX1	ENSG00000069011	0.6254458566308594	[12]	[18,17]	7	hSpCas9	negative selection	3309160
135029264	135029287		-	24336571	A375	viability after 14 days	GCGCGAGCGTAACCAGCAGCTGG	PITX1	ENSG00000069011	-0.14830268064820473	[10]	[7,9]	-2	hSpCas9	negative selection	3309161
135031321	135031344		-	24336571	A375	viability after 14 days	GCTACCCCGACATGAGCATGAGG	PITX1	ENSG00000069011	0.1610924118277637	[15]	[13,18]	2	hSpCas9	negative selection	3309163
135031265	135031288	5	+	27383988	293T	resistance to West Nile virus (flavivirus)	CCCTTGCTCACCCGCACGCGCGG	PITX1	ENSG00000069011	-0.7925223380047265	[264,264]	[0,0]	-5	hSpCas9	positive selection	3385995
135031276	135031299	5	-	27383988	293T	resistance to West Nile virus (flavivirus)	ACCTCACCGAGCCGCGCGTGCGG	PITX1	ENSG00000069011	4.660085380946242	[235,235]	[38,38]	9	hSpCas9	positive selection	3385996
135031493	135031516	5	-	26780180	HT29	viability (Avana library 4 designs)	ACTGCAGAGAAGGAGCGCGGCGG	PITX1	ENSG00000069011	2.59717298772661	[]	[]	8	hSpCas9	negative selection	3449605
135031408	135031431	5	-	26780180	HT29	viability (Avana library 4 designs)	CAGCCAAGAAGAAGAAGCAGCGG	PITX1	ENSG00000069011	0.248546315120511	[]	[]	0	hSpCas9	negative selection	3449606
135031496	135031519	5	-	26780180	HT29	viability (Avana library 4 designs)	CCTACTGCAGAGAAGGAGCGCGG	PITX1	ENSG00000069011	0.623207802846397	[]	[]	2	hSpCas9	negative selection	3449607
135031320	135031343	5	-	26780180	HT29	viability (Avana library 4 designs)	CTACCCCGACATGAGCATGAGGG	PITX1	ENSG00000069011	0.96885810759001	[]	[]	4	hSpCas9	negative selection	3449608
135031496	135031519	5	-	26780180	A375	viability (Avana lentiCRISPRv2)	CCTACTGCAGAGAAGGAGCGCGG	PITX1	ENSG00000069011	4.51597456544346	[]	[]	7	hSpCas9	negative selection	3544448
135031408	135031431	5	-	26780180	A375	viability (Avana lentiCRISPRv2)	CAGCCAAGAAGAAGAAGCAGCGG	PITX1	ENSG00000069011	3.13676101121992	[]	[]	5	hSpCas9	negative selection	3544449
135031493	135031516	5	-	26780180	A375	viability (Avana lentiCRISPRv2)	ACTGCAGAGAAGGAGCGCGGCGG	PITX1	ENSG00000069011	-2.48619741595085	[]	[]	-3	hSpCas9	negative selection	3544450
135031320	135031343	5	-	26780180	A375	viability (Avana lentiCRISPRv2)	CTACCCCGACATGAGCATGAGGG	PITX1	ENSG00000069011	-0.161641431008527	[]	[]	0	hSpCas9	negative selection	3544451
135031405	135031428	5	-	26780180	A375	viability (Avana lentiCRISPRv2)	CCAAGAAGAAGAAGCAGCGGCGG	PITX1	ENSG00000069011	2.59989479499555	[]	[]	4	hSpCas9	negative selection	3544452
135031496	135031519	5	-	26780180	A375	viability (Avana lentiGuide)	CCTACTGCAGAGAAGGAGCGCGG	PITX1	ENSG00000069011	2.73347456563563	[]	[]	3	hSpCas9	negative selection	3653107
135031408	135031431	5	-	26780180	A375	viability (Avana lentiGuide)	CAGCCAAGAAGAAGAAGCAGCGG	PITX1	ENSG00000069011	0.843995712185927	[]	[]	1	hSpCas9	negative selection	3653108
135031493	135031516	5	-	26780180	A375	viability (Avana lentiGuide)	ACTGCAGAGAAGGAGCGCGGCGG	PITX1	ENSG00000069011	4.45960853198551	[]	[]	4	hSpCas9	negative selection	3653109
135031320	135031343	5	-	26780180	A375	viability (Avana lentiGuide)	CTACCCCGACATGAGCATGAGGG	PITX1	ENSG00000069011	-6.16606312384235	[]	[]	-9	hSpCas9	negative selection	3653110
135031405	135031428	5	-	26780180	A375	viability (Avana lentiGuide)	CCAAGAAGAAGAAGCAGCGGCGG	PITX1	ENSG00000069011	18.3497835856629	[]	[]	8	hSpCas9	negative selection	3653111
135031496	135031519	5	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CCTACTGCAGAGAAGGAGCGCGG	PITX1	ENSG00000069011	0.15176628292382727	[5]	[6,5]	4	hSpCas9	positive selection	3761766
135031408	135031431	5	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CAGCCAAGAAGAAGAAGCAGCGG	PITX1	ENSG00000069011	0.0940746906331199	[4]	[3,4]	2	hSpCas9	positive selection	3761767
135031493	135031516	5	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ACTGCAGAGAAGGAGCGCGGCGG	PITX1	ENSG00000069011	-0.3396741907608538	[3]	[2,2]	-5	hSpCas9	positive selection	3761768
135031320	135031343	5	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CTACCCCGACATGAGCATGAGGG	PITX1	ENSG00000069011	0.05026592729132684	[4]	[4,4]	1	hSpCas9	positive selection	3761769
135031405	135031428	5	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CCAAGAAGAAGAAGCAGCGGCGG	PITX1	ENSG00000069011	-0.06827886470316613	[4]	[4,3]	-1	hSpCas9	positive selection	3761770
135031496	135031519	5	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CCTACTGCAGAGAAGGAGCGCGG	PITX1	ENSG00000069011	-0.13844895592968973	[6]	[3,5]	-2	hSpCas9	positive selection	3870373
135031408	135031431	5	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CAGCCAAGAAGAAGAAGCAGCGG	PITX1	ENSG00000069011	-0.4171711605918591	[4]	[4,0]	-5	hSpCas9	positive selection	3870374
135031493	135031516	5	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ACTGCAGAGAAGGAGCGCGGCGG	PITX1	ENSG00000069011	-1.2410064078980552	[4]	[0,1]	-9	hSpCas9	positive selection	3870375
135031320	135031343	5	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CTACCCCGACATGAGCATGAGGG	PITX1	ENSG00000069011	0.25361688031993346	[4]	[5,3]	6	hSpCas9	positive selection	3870376
135031405	135031428	5	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CCAAGAAGAAGAAGCAGCGGCGG	PITX1	ENSG00000069011	-1.3363753169993984	[4]	[1,0]	-9	hSpCas9	positive selection	3870377
135031276	135031299	5	-	26780180	A375	viability	ACCTCACCGAGCCGCGCGTGCGG	PITX1	ENSG00000069011	1.53163256782628	[]	[]	8	hSpCas9	negative selection	3981184
135031265	135031288	5	+	26780180	A375	viability	CCCTTGCTCACCCGCACGCGCGG	PITX1	ENSG00000069011	1.11992185516583	[]	[]	5	hSpCas9	negative selection	3981185
135029191	135029214	5	-	26780180	A375	viability	TACGAGGACGTGTACGCCGCCGG	PITX1	ENSG00000069011	1.3734741680616	[]	[]	7	hSpCas9	negative selection	3981186
135028837	135028860	5	-	26780180	A375	viability	TCCAAACAGCACTCGTCGTTTGG	PITX1	ENSG00000069011	0.136815553616133	[]	[]	0	hSpCas9	negative selection	3981187
135031276	135031299	5	-	26780180	HT29	viability (GeCKOv2 library)	ACCTCACCGAGCCGCGCGTGCGG	PITX1	ENSG00000069011	1.81922559867475	[]	[]	8	hSpCas9	negative selection	4089150
135031265	135031288	5	+	26780180	HT29	viability (GeCKOv2 library)	CCCTTGCTCACCCGCACGCGCGG	PITX1	ENSG00000069011	0.673516508439537	[]	[]	2	hSpCas9	negative selection	4089151
135029191	135029214	5	-	26780180	HT29	viability (GeCKOv2 library)	TACGAGGACGTGTACGCCGCCGG	PITX1	ENSG00000069011	1.50556625309642	[]	[]	7	hSpCas9	negative selection	4089152
135028837	135028860	5	-	26780180	HT29	viability (GeCKOv2 library)	TCCAAACAGCACTCGTCGTTTGG	PITX1	ENSG00000069011	-0.375506819861893	[]	[]	-8	hSpCas9	negative selection	4089153
135031265	135031288	5	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CCCTTGCTCACCCGCACGCGCGG	PITX1	ENSG00000069011	-0.1851501707779234	[3]	[1,2]	-4	hSpCas9	positive selection	4160748
135028836	135028859	5	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GCCAAACGACGAGTGCTGTTTGG	PITX1	ENSG00000069011	0.25715308480528326	[3]	[2,3]	6	hSpCas9	positive selection	4160749
135029264	135029287	5	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GCGCGAGCGTAACCAGCAGCTGG	PITX1	ENSG00000069011	-0.24352027752225908	[3]	[1,2]	-5	hSpCas9	positive selection	4160750
135031321	135031344	5	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GCTACCCCGACATGAGCATGAGG	PITX1	ENSG00000069011	-0.42700168178321096	[4]	[1,1]	-8	hSpCas9	positive selection	4160753
135031265	135031288	5	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CCCTTGCTCACCCGCACGCGCGG	PITX1	ENSG00000069011	0.7990136010455972	[3]	[2,0,1,3]	5	hSpCas9	positive selection	4224770
135028836	135028859	5	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GCCAAACGACGAGTGCTGTTTGG	PITX1	ENSG00000069011	0.8139048638801993	[1]	[2,0,3,0]	5	hSpCas9	positive selection	4224771
135029264	135029287	5	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GCGCGAGCGTAACCAGCAGCTGG	PITX1	ENSG00000069011	0.5095555675068806	[3]	[0,3,0,1]	3	hSpCas9	positive selection	4224772
135031321	135031344	5	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GCTACCCCGACATGAGCATGAGG	PITX1	ENSG00000069011	0.1453292454499176	[3]	[2,3,2,0]	1	hSpCas9	positive selection	4224775
135028837	135028860	5	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TCCAAACAGCACTCGTCGTTTGG	PITX1	ENSG00000069011	0.3533350319461202	[4]	[5,3]	7	hSpCas9	positive selection	4290412
135029191	135029214	5	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TACGAGGACGTGTACGCCGCCGG	PITX1	ENSG00000069011	-0.5625004483228618	[2]	[1,0]	-8	hSpCas9	positive selection	4290413
135031265	135031288	5	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCCTTGCTCACCCGCACGCGCGG	PITX1	ENSG00000069011	0.07113932954199997	[3]	[3,2]	1	hSpCas9	positive selection	4354664
135031276	135031299	5	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ACCTCACCGAGCCGCGCGTGCGG	PITX1	ENSG00000069011	0.03730916442502409	[3]	[3,1]	0	hSpCas9	positive selection	4354665
135029219	135029241	5	+	27760321	OCIAML3	viability	GCACTAGGCCGCTGAACTGCGG	PITX1	ENSG00000069011	-0.07134411124526102	[644,621]	[362,614]	-1	hSpCas9	negative selection	4428045
135031317	135031339	5	-	27760321	OCIAML3	viability	CCCGACATGAGCATGAGGGAGG	PITX1	ENSG00000069011	-0.031098127944898135	[661,489]	[330,574]	0	hSpCas9	negative selection	4428046
135031481	135031503	5	-	27760321	OCIAML3	viability	AGCGCGGCGGGGAACCCAAGGG	PITX1	ENSG00000069011	-0.6336140411498115	[271,230]	[154,88]	-6	hSpCas9	negative selection	4428047
135029219	135029241	5	+	27760321	OCIAML2	viability	GCACTAGGCCGCTGAACTGCGG	PITX1	ENSG00000069011	-0.014234121760864249	[644,621]	[497,521]	0	hSpCas9	negative selection	4511508
135031317	135031339	5	-	27760321	OCIAML2	viability	CCCGACATGAGCATGAGGGAGG	PITX1	ENSG00000069011	0.3868905995047311	[661,489]	[526,704]	5	hSpCas9	negative selection	4511509
135031481	135031503	5	-	27760321	OCIAML2	viability	AGCGCGGCGGGGAACCCAAGGG	PITX1	ENSG00000069011	0.3432687396996947	[271,230]	[223,300]	4	hSpCas9	negative selection	4511510
135029219	135029241	5	+	27760321	MV411	viability	GCACTAGGCCGCTGAACTGCGG	PITX1	ENSG00000069011	-0.9662615727776142	[644,621]	[157,298]	-6	hSpCas9	negative selection	4594971
135031317	135031339	5	-	27760321	MV411	viability	CCCGACATGAGCATGAGGGAGG	PITX1	ENSG00000069011	-0.8424632494090778	[661,489]	[62,430]	-5	hSpCas9	negative selection	4594972
135031481	135031503	5	-	27760321	MV411	viability	AGCGCGGCGGGGAACCCAAGGG	PITX1	ENSG00000069011	-1.9313584556455328	[271,230]	[0,106]	-8	hSpCas9	negative selection	4594973
135029219	135029241	5	+	27760321	HL60	viability	GCACTAGGCCGCTGAACTGCGG	PITX1	ENSG00000069011	0.8309721490186875	[644,621]	[1127,703]	8	hSpCas9	negative selection	4678434
135031317	135031339	5	-	27760321	HL60	viability	CCCGACATGAGCATGAGGGAGG	PITX1	ENSG00000069011	0.7694309727554136	[661,489]	[905,676]	8	hSpCas9	negative selection	4678435
135031481	135031503	5	-	27760321	HL60	viability	AGCGCGGCGGGGAACCCAAGGG	PITX1	ENSG00000069011	0.18707341028844438	[271,230]	[202,264]	2	hSpCas9	negative selection	4678436
135029219	135029241	5	+	27760321	HT1080	viability	GCACTAGGCCGCTGAACTGCGG	PITX1	ENSG00000069011	-0.11631427991999022	[621,485]	[184,223]	0	hSpCas9	negative selection	4761897
135031317	135031339	5	-	27760321	HT1080	viability	CCCGACATGAGCATGAGGGAGG	PITX1	ENSG00000069011	0.9576835462193021	[489,382]	[300,377]	5	hSpCas9	negative selection	4761898
135031481	135031503	5	-	27760321	HT1080	viability	AGCGCGGCGGGGAACCCAAGGG	PITX1	ENSG00000069011	0.8299610236197223	[230,179]	[208,75]	4	hSpCas9	negative selection	4761899
135029219	135029241	5	+	27760321	HT29	viability after 7 days	GCACTAGGCCGCTGAACTGCGG	PITX1	ENSG00000069011	-0.16884081060233946	[621,485]	[997,446,510]	-2	hSpCas9	negative selection	4845360
135031317	135031339	5	-	27760321	HT29	viability after 7 days	CCCGACATGAGCATGAGGGAGG	PITX1	ENSG00000069011	0.20454284735936812	[489,382]	[891,711,378]	3	hSpCas9	negative selection	4845361
135031481	135031503	5	-	27760321	HT29	viability after 7 days	AGCGCGGCGGGGAACCCAAGGG	PITX1	ENSG00000069011	0.41530608025201193	[230,179]	[229,424,382]	6	hSpCas9	negative selection	4845362
135029219	135029241	5	+	27760321	HT29	viability after 25 days	GCACTAGGCCGCTGAACTGCGG	PITX1	ENSG00000069011	0.07029578871382747	[621,485]	[615,589,804]	0	hSpCas9	negative selection	4928823
135031317	135031339	5	-	27760321	HT29	viability after 25 days	CCCGACATGAGCATGAGGGAGG	PITX1	ENSG00000069011	0.8968254203028554	[489,382]	[940,1022,807]	9	hSpCas9	negative selection	4928824
135031481	135031503	5	-	27760321	HT29	viability after 25 days	AGCGCGGCGGGGAACCCAAGGG	PITX1	ENSG00000069011	1.047892865335482	[230,179]	[446,561,444]	9	hSpCas9	negative selection	4928825
135029219	135029241	5	+	27760321	HT29	viability after 22 days	GCACTAGGCCGCTGAACTGCGG	PITX1	ENSG00000069011	0.0814455627441053	[621,485]	[465,871,700]	0	hSpCas9	negative selection	5012286
135031317	135031339	5	-	27760321	HT29	viability after 22 days	CCCGACATGAGCATGAGGGAGG	PITX1	ENSG00000069011	0.8648026795555006	[489,382]	[918,1030,805]	8	hSpCas9	negative selection	5012287
135031481	135031503	5	-	27760321	HT29	viability after 22 days	AGCGCGGCGGGGAACCCAAGGG	PITX1	ENSG00000069011	1.2482591408056454	[230,179]	[606,490,593]	9	hSpCas9	negative selection	5012288
135029219	135029241	5	+	27760321	HT29	viability after 19 days	GCACTAGGCCGCTGAACTGCGG	PITX1	ENSG00000069011	0.6810332169771349	[621,485]	[1070,1399,597]	7	hSpCas9	negative selection	5095749
135031317	135031339	5	-	27760321	HT29	viability after 19 days	CCCGACATGAGCATGAGGGAGG	PITX1	ENSG00000069011	0.7469276345818259	[489,382]	[1095,711,735]	7	hSpCas9	negative selection	5095750
135031481	135031503	5	-	27760321	HT29	viability after 19 days	AGCGCGGCGGGGAACCCAAGGG	PITX1	ENSG00000069011	1.1965011690512717	[230,179]	[425,327,837]	9	hSpCas9	negative selection	5095751
135029219	135029241	5	+	27760321	HT29	viability after 16 days	GCACTAGGCCGCTGAACTGCGG	PITX1	ENSG00000069011	0.29858351148238427	[621,485]	[920,686,695]	3	hSpCas9	negative selection	5179212
135031317	135031339	5	-	27760321	HT29	viability after 16 days	CCCGACATGAGCATGAGGGAGG	PITX1	ENSG00000069011	0.759831694768605	[489,382]	[1124,713,672]	8	hSpCas9	negative selection	5179213
135031481	135031503	5	-	27760321	HT29	viability after 16 days	AGCGCGGCGGGGAACCCAAGGG	PITX1	ENSG00000069011	1.0407358389162766	[230,179]	[413,748,242]	9	hSpCas9	negative selection	5179214
135029219	135029241	5	+	27760321	HT29	viability after 13 days	GCACTAGGCCGCTGAACTGCGG	PITX1	ENSG00000069011	0.19096091918863123	[621,485]	[586,857,754]	2	hSpCas9	negative selection	5262675
135031317	135031339	5	-	27760321	HT29	viability after 13 days	CCCGACATGAGCATGAGGGAGG	PITX1	ENSG00000069011	0.5930519326520671	[489,382]	[786,713,788]	7	hSpCas9	negative selection	5262676
135031481	135031503	5	-	27760321	HT29	viability after 13 days	AGCGCGGCGGGGAACCCAAGGG	PITX1	ENSG00000069011	0.6194916577913133	[230,179]	[385,489,230]	7	hSpCas9	negative selection	5262677
135029219	135029241	5	+	27760321	HT29	viability after 10 days	GCACTAGGCCGCTGAACTGCGG	PITX1	ENSG00000069011	0.3837781074862463	[621,485]	[798,857,1045]	5	hSpCas9	negative selection	5346138
135031317	135031339	5	-	27760321	HT29	viability after 10 days	CCCGACATGAGCATGAGGGAGG	PITX1	ENSG00000069011	0.5300018543101042	[489,382]	[677,857,825]	7	hSpCas9	negative selection	5346139
135031481	135031503	5	-	27760321	HT29	viability after 10 days	AGCGCGGCGGGGAACCCAAGGG	PITX1	ENSG00000069011	0.6397089808419631	[230,179]	[257,621,326]	8	hSpCas9	negative selection	5346140
135029219	135029241	5	+	27760321	MOLM13	viability	GCACTAGGCCGCTGAACTGCGG	PITX1	ENSG00000069011	-0.14234253867814645	[644,621]	[264,374]	-1	hSpCas9	negative selection	5429601
135031317	135031339	5	-	27760321	MOLM13	viability	CCCGACATGAGCATGAGGGAGG	PITX1	ENSG00000069011	-0.47854814579290256	[661,489]	[356,123]	-3	hSpCas9	negative selection	5429602
135031481	135031503	5	-	27760321	MOLM13	viability	AGCGCGGCGGGGAACCCAAGGG	PITX1	ENSG00000069011	-1.148062229122006	[271,230]	[99,32]	-6	hSpCas9	negative selection	5429603
135028837	135028860	5	-	27260156	BXPC3	viability	TCCAAACAGCACTCGTCGTTTGG	PITX1	ENSG00000069011	0.30099440522698684	[1134]	[1295,1496,1405,1680]	6	hSpCas9	negative selection	5562872
135029191	135029214	5	-	27260156	BXPC3	viability	TACGAGGACGTGTACGCCGCCGG	PITX1	ENSG00000069011	-0.07140838975347186	[236]	[183,237,225,307]	-2	hSpCas9	negative selection	5562873
135031265	135031288	5	+	27260156	BXPC3	viability	CCCTTGCTCACCCGCACGCGCGG	PITX1	ENSG00000069011	0.2098382172676675	[916]	[1114,907,1183,1250]	4	hSpCas9	negative selection	5627124
135031276	135031299	5	-	27260156	BXPC3	viability	ACCTCACCGAGCCGCGCGTGCGG	PITX1	ENSG00000069011	0.3942722880054473	[499]	[596,790,562,808]	8	hSpCas9	negative selection	5627125
135028837	135028860	5	-	27260156	A673	viability	TCCAAACAGCACTCGTCGTTTGG	PITX1	ENSG00000069011	0.22400835734856384	[1134]	[1847,1537,1379,1632]	5	hSpCas9	negative selection	5684123
135029191	135029214	5	-	27260156	A673	viability	TACGAGGACGTGTACGCCGCCGG	PITX1	ENSG00000069011	-0.2955689866181235	[236]	[236,154,288,248]	-6	hSpCas9	negative selection	5684124
135031265	135031288	5	+	27260156	A673	viability	CCCTTGCTCACCCGCACGCGCGG	PITX1	ENSG00000069011	-0.09739992196603697	[916]	[1256,1057,831,992]	-2	hSpCas9	negative selection	5748375
135031276	135031299	5	-	27260156	A673	viability	ACCTCACCGAGCCGCGCGTGCGG	PITX1	ENSG00000069011	0.1344921259520359	[499]	[721,510,753,657]	3	hSpCas9	negative selection	5748376
135028837	135028860	5	-	27260156	A375	viability	TCCAAACAGCACTCGTCGTTTGG	PITX1	ENSG00000069011	0.45750038483632616	[1134]	[1675,2369,1624,1693]	6	hSpCas9	negative selection	5805374
135029191	135029214	5	-	27260156	A375	viability	TACGAGGACGTGTACGCCGCCGG	PITX1	ENSG00000069011	-0.26530285333400094	[236]	[315,257,158,195]	-4	hSpCas9	negative selection	5805375
135031265	135031288	5	+	27260156	A375	viability	CCCTTGCTCACCCGCACGCGCGG	PITX1	ENSG00000069011	-0.05108124325256613	[916]	[921,1108,1105,1006]	0	hSpCas9	negative selection	5869626
135031276	135031299	5	-	27260156	A375	viability	ACCTCACCGAGCCGCGCGTGCGG	PITX1	ENSG00000069011	0.08997554519602204	[499]	[878,638,540,449]	1	hSpCas9	negative selection	5869627
135028837	135028860	5	-	27260156	COLO741	viability	TCCAAACAGCACTCGTCGTTTGG	PITX1	ENSG00000069011	0.29905805835724797	[1134]	[2020,1586,1761]	6	hSpCas9	negative selection	5926625
135029191	135029214	5	-	27260156	COLO741	viability	TACGAGGACGTGTACGCCGCCGG	PITX1	ENSG00000069011	-0.14336412468569937	[236]	[289,283,250]	-3	hSpCas9	negative selection	5926626
135031265	135031288	5	+	27260156	COLO741	viability	CCCTTGCTCACCCGCACGCGCGG	PITX1	ENSG00000069011	0.050622773354781825	[916]	[1261,1433,964]	1	hSpCas9	negative selection	5990877
135031276	135031299	5	-	27260156	COLO741	viability	ACCTCACCGAGCCGCGCGTGCGG	PITX1	ENSG00000069011	0.41940330192055275	[499]	[1057,789,738]	8	hSpCas9	negative selection	5990878
135028837	135028860	5	-	27260156	CAL120	viability	TCCAAACAGCACTCGTCGTTTGG	PITX1	ENSG00000069011	0.37679411329597445	[1134]	[2275,1877,1420]	5	hSpCas9	negative selection	6047876
135029191	135029214	5	-	27260156	CAL120	viability	TACGAGGACGTGTACGCCGCCGG	PITX1	ENSG00000069011	-0.3601042483189718	[236]	[210,278,196]	-5	hSpCas9	negative selection	6047877
135031265	135031288	5	+	27260156	CAL120	viability	CCCTTGCTCACCCGCACGCGCGG	PITX1	ENSG00000069011	-0.06663873134094744	[916]	[1496,763,1068]	-1	hSpCas9	negative selection	6112128
135031276	135031299	5	-	27260156	CAL120	viability	ACCTCACCGAGCCGCGCGTGCGG	PITX1	ENSG00000069011	0.34171439219843386	[499]	[947,645,794]	5	hSpCas9	negative selection	6112129
135028837	135028860	5	-	27260156	CADOES1	viability	TCCAAACAGCACTCGTCGTTTGG	PITX1	ENSG00000069011	0.41954299904166503	[1134]	[1413,1245,1324,1671]	7	hSpCas9	negative selection	6169127
135029191	135029214	5	-	27260156	CADOES1	viability	TACGAGGACGTGTACGCCGCCGG	PITX1	ENSG00000069011	0.13116297924638265	[236]	[268,346,153,193]	2	hSpCas9	negative selection	6169128
135031265	135031288	5	+	27260156	CADOES1	viability	CCCTTGCTCACCCGCACGCGCGG	PITX1	ENSG00000069011	0.05964349353079246	[916]	[1034,832,822,862]	1	hSpCas9	negative selection	6233379
135031276	135031299	5	-	27260156	CADOES1	viability	ACCTCACCGAGCCGCGCGTGCGG	PITX1	ENSG00000069011	0.3540663403818025	[499]	[397,789,555,635]	6	hSpCas9	negative selection	6233380
135028837	135028860	5	-	27260156	EWS502	viability	TCCAAACAGCACTCGTCGTTTGG	PITX1	ENSG00000069011	0.6751628259462745	[1134]	[1732,1535,2089,2385]	9	hSpCas9	negative selection	6290378
135029191	135029214	5	-	27260156	EWS502	viability	TACGAGGACGTGTACGCCGCCGG	PITX1	ENSG00000069011	-0.2878644605005096	[236]	[134,312,145,232]	-5	hSpCas9	negative selection	6290379
135031265	135031288	5	+	27260156	EWS502	viability	CCCTTGCTCACCCGCACGCGCGG	PITX1	ENSG00000069011	-0.08369023685569243	[916]	[812,840,995,1037]	-1	hSpCas9	negative selection	6354630
135031276	135031299	5	-	27260156	EWS502	viability	ACCTCACCGAGCCGCGCGTGCGG	PITX1	ENSG00000069011	0.31870612599332754	[499]	[531,610,804,714]	5	hSpCas9	negative selection	6354631
135028837	135028860	5	-	27260156	EW8	viability	TCCAAACAGCACTCGTCGTTTGG	PITX1	ENSG00000069011	0.34071421174833527	[1134]	[1222,1420,891,1173]	6	hSpCas9	negative selection	6411629
135029191	135029214	5	-	27260156	EW8	viability	TACGAGGACGTGTACGCCGCCGG	PITX1	ENSG00000069011	0.52547673341212	[236]	[592,228,140,199]	8	hSpCas9	negative selection	6411630
135031265	135031288	5	+	27260156	EW8	viability	CCCTTGCTCACCCGCACGCGCGG	PITX1	ENSG00000069011	-0.08894388539652553	[916]	[578,771,583,863]	-2	hSpCas9	negative selection	6475881
135031276	135031299	5	-	27260156	EW8	viability	ACCTCACCGAGCCGCGCGTGCGG	PITX1	ENSG00000069011	0.21236757237247195	[499]	[465,595,331,505]	4	hSpCas9	negative selection	6475882
135028837	135028860	5	-	27260156	CORL105	viability	TCCAAACAGCACTCGTCGTTTGG	PITX1	ENSG00000069011	0.515858755024893	[1134]	[1816,1854,2222,1752]	8	hSpCas9	negative selection	6532880
135029191	135029214	5	-	27260156	CORL105	viability	TACGAGGACGTGTACGCCGCCGG	PITX1	ENSG00000069011	-0.4203823972993004	[236]	[191,178,281,187]	-6	hSpCas9	negative selection	6532881
135031265	135031288	5	+	27260156	CORL105	viability	CCCTTGCTCACCCGCACGCGCGG	PITX1	ENSG00000069011	0.10881760649659011	[916]	[1303,900,1465,1017]	2	hSpCas9	negative selection	6597132
135031276	135031299	5	-	27260156	CORL105	viability	ACCTCACCGAGCCGCGCGTGCGG	PITX1	ENSG00000069011	0.40228721168014275	[499]	[763,724,976,660]	7	hSpCas9	negative selection	6597133
135028837	135028860	5	-	27260156	HS294T	viability	TCCAAACAGCACTCGTCGTTTGG	PITX1	ENSG00000069011	0.8635440962326306	[1134]	[596,870,653,1143]	9	hSpCas9	negative selection	6654131
135029191	135029214	5	-	27260156	HS294T	viability	TACGAGGACGTGTACGCCGCCGG	PITX1	ENSG00000069011	-0.02284518494909582	[236]	[96,83,73,107]	0	hSpCas9	negative selection	6654132
135031265	135031288	5	+	27260156	HS294T	viability	CCCTTGCTCACCCGCACGCGCGG	PITX1	ENSG00000069011	-0.5569850191136523	[916]	[214,208,260,289]	-7	hSpCas9	negative selection	6718383
135031276	135031299	5	-	27260156	HS294T	viability	ACCTCACCGAGCCGCGCGTGCGG	PITX1	ENSG00000069011	0.07463143130358436	[499]	[224,178,241,158]	1	hSpCas9	negative selection	6718384
135028837	135028860	5	-	27260156	HCC44	viability	TCCAAACAGCACTCGTCGTTTGG	PITX1	ENSG00000069011	0.3665812302114515	[1134]	[1927,1244,2310,1329]	6	hSpCas9	negative selection	6775382
135029191	135029214	5	-	27260156	HCC44	viability	TACGAGGACGTGTACGCCGCCGG	PITX1	ENSG00000069011	-0.2062636160496052	[236]	[206,195,225,297]	-3	hSpCas9	negative selection	6775383
135031265	135031288	5	+	27260156	HCC44	viability	CCCTTGCTCACCCGCACGCGCGG	PITX1	ENSG00000069011	0.007906511213162104	[916]	[1252,865,1127,976]	0	hSpCas9	negative selection	6839634
135031276	135031299	5	-	27260156	HCC44	viability	ACCTCACCGAGCCGCGCGTGCGG	PITX1	ENSG00000069011	0.4163525911738045	[499]	[832,518,959,775]	7	hSpCas9	negative selection	6839635
135028837	135028860	5	-	27260156	G402	viability	TCCAAACAGCACTCGTCGTTTGG	PITX1	ENSG00000069011	0.3622409875666379	[1134]	[1741,1331,1859,2130]	4	hSpCas9	negative selection	6896633
135029191	135029214	5	-	27260156	G402	viability	TACGAGGACGTGTACGCCGCCGG	PITX1	ENSG00000069011	-0.18348971944555026	[236]	[570,94,238,153]	-2	hSpCas9	negative selection	6896634
135031265	135031288	5	+	27260156	G402	viability	CCCTTGCTCACCCGCACGCGCGG	PITX1	ENSG00000069011	0.05725663306055895	[916]	[1086,1027,1601,927]	0	hSpCas9	negative selection	6960885
135031276	135031299	5	-	27260156	G402	viability	ACCTCACCGAGCCGCGCGTGCGG	PITX1	ENSG00000069011	0.4471655922143648	[499]	[1024,887,650,792]	5	hSpCas9	negative selection	6960886
135028837	135028860	5	-	27260156	L33	viability	TCCAAACAGCACTCGTCGTTTGG	PITX1	ENSG00000069011	0.3815156374940769	[1134]	[1505,705,752,1484]	7	hSpCas9	negative selection	7017884
135029191	135029214	5	-	27260156	L33	viability	TACGAGGACGTGTACGCCGCCGG	PITX1	ENSG00000069011	-0.4655348225902167	[236]	[226,27,115,204]	-8	hSpCas9	negative selection	7017885
135031265	135031288	5	+	27260156	L33	viability	CCCTTGCTCACCCGCACGCGCGG	PITX1	ENSG00000069011	-0.08190470447748266	[916]	[806,355,485,1015]	-2	hSpCas9	negative selection	7082136
135031276	135031299	5	-	27260156	L33	viability	ACCTCACCGAGCCGCGCGTGCGG	PITX1	ENSG00000069011	0.00788218953075906	[499]	[536,199,335,450]	0	hSpCas9	negative selection	7082137
135028837	135028860	5	-	27260156	K562	viability	TCCAAACAGCACTCGTCGTTTGG	PITX1	ENSG00000069011	0.3756298044792463	[1134]	[1577,1321,1041,1302]	5	hSpCas9	negative selection	7139135
135029191	135029214	5	-	27260156	K562	viability	TACGAGGACGTGTACGCCGCCGG	PITX1	ENSG00000069011	0.24663917969178395	[236]	[280,195,469,70]	3	hSpCas9	negative selection	7139136
135031265	135031288	5	+	27260156	K562	viability	CCCTTGCTCACCCGCACGCGCGG	PITX1	ENSG00000069011	0.24282113460290222	[916]	[997,825,1043,973]	3	hSpCas9	negative selection	7203387
135031276	135031299	5	-	27260156	K562	viability	ACCTCACCGAGCCGCGCGTGCGG	PITX1	ENSG00000069011	0.5755871469457048	[499]	[488,725,1023,420]	7	hSpCas9	negative selection	7203388
135028837	135028860	5	-	27260156	HT29	viability	TCCAAACAGCACTCGTCGTTTGG	PITX1	ENSG00000069011	0.32102276596751	[1134]	[1983,1646,1709,1572]	6	hSpCas9	negative selection	7260386
135029191	135029214	5	-	27260156	HT29	viability	TACGAGGACGTGTACGCCGCCGG	PITX1	ENSG00000069011	-0.1635129274610132	[236]	[315,209,176,316]	-3	hSpCas9	negative selection	7260387
135031265	135031288	5	+	27260156	HT29	viability	CCCTTGCTCACCCGCACGCGCGG	PITX1	ENSG00000069011	0.1890800544467367	[916]	[1466,1159,1140,1306]	3	hSpCas9	negative selection	7324638
135031276	135031299	5	-	27260156	HT29	viability	ACCTCACCGAGCCGCGCGTGCGG	PITX1	ENSG00000069011	0.20047480945854534	[499]	[705,832,601,663]	4	hSpCas9	negative selection	7324639
135028837	135028860	5	-	27260156	MHHES1	viability	TCCAAACAGCACTCGTCGTTTGG	PITX1	ENSG00000069011	0.44107459964677	[1134]	[1676,2014,1483,1742]	7	hSpCas9	negative selection	7381637
135029191	135029214	5	-	27260156	MHHES1	viability	TACGAGGACGTGTACGCCGCCGG	PITX1	ENSG00000069011	-0.14336688035333922	[236]	[197,418,225,151]	-3	hSpCas9	negative selection	7381638
135031265	135031288	5	+	27260156	MHHES1	viability	CCCTTGCTCACCCGCACGCGCGG	PITX1	ENSG00000069011	-0.3304644572061346	[916]	[850,848,906,695]	-6	hSpCas9	negative selection	7445889
135031276	135031299	5	-	27260156	MHHES1	viability	ACCTCACCGAGCCGCGCGTGCGG	PITX1	ENSG00000069011	0.3964884711176558	[499]	[766,1128,721,442]	7	hSpCas9	negative selection	7445890
135028837	135028860	5	-	27260156	MEWO	viability	TCCAAACAGCACTCGTCGTTTGG	PITX1	ENSG00000069011	0.23284990026359842	[1134]	[1451,1212,1117]	5	hSpCas9	negative selection	7502888
135029191	135029214	5	-	27260156	MEWO	viability	TACGAGGACGTGTACGCCGCCGG	PITX1	ENSG00000069011	-0.21662203653370238	[236]	[244,169,167]	-5	hSpCas9	negative selection	7502889
135031265	135031288	5	+	27260156	MEWO	viability	CCCTTGCTCACCCGCACGCGCGG	PITX1	ENSG00000069011	-0.06439032390389055	[916]	[885,594,993]	-1	hSpCas9	negative selection	7567140
135031276	135031299	5	-	27260156	MEWO	viability	ACCTCACCGAGCCGCGCGTGCGG	PITX1	ENSG00000069011	0.30937790344631205	[499]	[676,520,559]	6	hSpCas9	negative selection	7567141
135028837	135028860	5	-	27260156	LNCAPCLONEFGC	viability	TCCAAACAGCACTCGTCGTTTGG	PITX1	ENSG00000069011	0.44716600245062477	[1134]	[1244,1268,2103,1103]	7	hSpCas9	negative selection	7624139
135029191	135029214	5	-	27260156	LNCAPCLONEFGC	viability	TACGAGGACGTGTACGCCGCCGG	PITX1	ENSG00000069011	-0.25408804394546713	[236]	[194,161,180,182]	-4	hSpCas9	negative selection	7624140
135031265	135031288	5	+	27260156	LNCAPCLONEFGC	viability	CCCTTGCTCACCCGCACGCGCGG	PITX1	ENSG00000069011	-0.3658302097188887	[916]	[660,621,622,669]	-5	hSpCas9	negative selection	7688391
135031276	135031299	5	-	27260156	LNCAPCLONEFGC	viability	ACCTCACCGAGCCGCGCGTGCGG	PITX1	ENSG00000069011	0.2829290430614954	[499]	[635,446,664,477]	4	hSpCas9	negative selection	7688392
135028837	135028860	5	-	27260156	PANC0327	viability	TCCAAACAGCACTCGTCGTTTGG	PITX1	ENSG00000069011	0.4410422910447036	[1134]	[1381,1410,1246,1429]	6	hSpCas9	negative selection	7745390
135029191	135029214	5	-	27260156	PANC0327	viability	TACGAGGACGTGTACGCCGCCGG	PITX1	ENSG00000069011	0.05431548711469181	[236]	[239,209,120,305]	0	hSpCas9	negative selection	7745391
135031265	135031288	5	+	27260156	PANC0327	viability	CCCTTGCTCACCCGCACGCGCGG	PITX1	ENSG00000069011	0.21694387749751287	[916]	[1108,787,1145,777]	3	hSpCas9	negative selection	7809642
135031276	135031299	5	-	27260156	PANC0327	viability	ACCTCACCGAGCCGCGCGTGCGG	PITX1	ENSG00000069011	0.5193243116233359	[499]	[358,917,570,638]	7	hSpCas9	negative selection	7809643
135028837	135028860	5	-	27260156	NCIH2009	viability	TCCAAACAGCACTCGTCGTTTGG	PITX1	ENSG00000069011	0.6562725856380631	[1134]	[2511,2545,2436]	8	hSpCas9	negative selection	7866641
135029191	135029214	5	-	27260156	NCIH2009	viability	TACGAGGACGTGTACGCCGCCGG	PITX1	ENSG00000069011	-0.5046437192257232	[236]	[282,154,272]	-6	hSpCas9	negative selection	7866642
135031265	135031288	5	+	27260156	NCIH2009	viability	CCCTTGCTCACCCGCACGCGCGG	PITX1	ENSG00000069011	0.25762595809713595	[916]	[2009,1199,1482]	3	hSpCas9	negative selection	7930893
135031276	135031299	5	-	27260156	NCIH2009	viability	ACCTCACCGAGCCGCGCGTGCGG	PITX1	ENSG00000069011	0.5541624875344644	[499]	[1165,1090,844]	7	hSpCas9	negative selection	7930894
135028837	135028860	5	-	27260156	NCIH1373	viability	TCCAAACAGCACTCGTCGTTTGG	PITX1	ENSG00000069011	1.0177144080126939	[1134]	[3464,2380,2671,495]	9	hSpCas9	negative selection	7987892
135029191	135029214	5	-	27260156	NCIH1373	viability	TACGAGGACGTGTACGCCGCCGG	PITX1	ENSG00000069011	-0.21672720773022425	[236]	[160,234,160,92]	-2	hSpCas9	negative selection	7987893
135031265	135031288	5	+	27260156	NCIH1373	viability	CCCTTGCTCACCCGCACGCGCGG	PITX1	ENSG00000069011	-0.8068990290308519	[916]	[641,688,538,122]	-7	hSpCas9	negative selection	8052144
135031276	135031299	5	-	27260156	NCIH1373	viability	ACCTCACCGAGCCGCGCGTGCGG	PITX1	ENSG00000069011	0.49550639421096965	[499]	[1320,401,875,176]	5	hSpCas9	negative selection	8052145
135028837	135028860	5	-	27260156	PATU8902	viability	TCCAAACAGCACTCGTCGTTTGG	PITX1	ENSG00000069011	0.6501782562650407	[1134]	[2409,1878,2919,2591]	6	hSpCas9	negative selection	8109143
135029191	135029214	5	-	27260156	PATU8902	viability	TACGAGGACGTGTACGCCGCCGG	PITX1	ENSG00000069011	-1.2894854695548577	[236]	[42,174,54,308]	-8	hSpCas9	negative selection	8109144
135031265	135031288	5	+	27260156	PATU8902	viability	CCCTTGCTCACCCGCACGCGCGG	PITX1	ENSG00000069011	-0.4460838399682069	[916]	[711,1064,1016,929]	-4	hSpCas9	negative selection	8173395
135031276	135031299	5	-	27260156	PATU8902	viability	ACCTCACCGAGCCGCGCGTGCGG	PITX1	ENSG00000069011	0.4613444265819153	[499]	[909,960,701,1370]	5	hSpCas9	negative selection	8173396
135028837	135028860	5	-	27260156	PANC1	viability	TCCAAACAGCACTCGTCGTTTGG	PITX1	ENSG00000069011	0.6470636447283504	[1134]	[1561,2075,1495,1125]	9	hSpCas9	negative selection	8230394
135029191	135029214	5	-	27260156	PANC1	viability	TACGAGGACGTGTACGCCGCCGG	PITX1	ENSG00000069011	-0.2154692210649185	[236]	[239,266,140,82]	-3	hSpCas9	negative selection	8230395
135031265	135031288	5	+	27260156	PANC1	viability	CCCTTGCTCACCCGCACGCGCGG	PITX1	ENSG00000069011	-0.2391329556047458	[916]	[453,922,807,550]	-4	hSpCas9	negative selection	8294646
135031276	135031299	5	-	27260156	PANC1	viability	ACCTCACCGAGCCGCGCGTGCGG	PITX1	ENSG00000069011	0.1826207168884647	[499]	[409,477,560,491]	3	hSpCas9	negative selection	8294647
135028837	135028860	5	-	27260156	PANC0813	viability	TCCAAACAGCACTCGTCGTTTGG	PITX1	ENSG00000069011	0.5256573424033022	[1134]	[1977,1997,1994,1719]	8	hSpCas9	negative selection	8351645
135029191	135029214	5	-	27260156	PANC0813	viability	TACGAGGACGTGTACGCCGCCGG	PITX1	ENSG00000069011	-0.2740215902634535	[236]	[392,159,78,298]	-4	hSpCas9	negative selection	8351646
135031265	135031288	5	+	27260156	PANC0813	viability	CCCTTGCTCACCCGCACGCGCGG	PITX1	ENSG00000069011	-0.1481433315746783	[916]	[859,1055,1053,909]	-2	hSpCas9	negative selection	8415897
135031276	135031299	5	-	27260156	PANC0813	viability	ACCTCACCGAGCCGCGCGTGCGG	PITX1	ENSG00000069011	0.18434689157837747	[499]	[749,667,561,693]	3	hSpCas9	negative selection	8415898
135028837	135028860	5	-	27260156	RDES	viability	TCCAAACAGCACTCGTCGTTTGG	PITX1	ENSG00000069011	0.4812904480899778	[1134]	[1746,1427,1884,2298]	7	hSpCas9	negative selection	8472896
135029191	135029214	5	-	27260156	RDES	viability	TACGAGGACGTGTACGCCGCCGG	PITX1	ENSG00000069011	-0.16465881495403467	[236]	[212,164,244,376]	-3	hSpCas9	negative selection	8472897
135031265	135031288	5	+	27260156	RDES	viability	CCCTTGCTCACCCGCACGCGCGG	PITX1	ENSG00000069011	-0.02171217703344508	[916]	[820,958,1121,1323]	0	hSpCas9	negative selection	8537148
135031276	135031299	5	-	27260156	RDES	viability	ACCTCACCGAGCCGCGCGTGCGG	PITX1	ENSG00000069011	0.46999231178433476	[499]	[598,698,948,1005]	7	hSpCas9	negative selection	8537149
135028837	135028860	5	-	27260156	PC3	viability	TCCAAACAGCACTCGTCGTTTGG	PITX1	ENSG00000069011	0.2635229983710732	[1134]	[1101,1336,2052,1146]	6	hSpCas9	negative selection	8594147
135029191	135029214	5	-	27260156	PC3	viability	TACGAGGACGTGTACGCCGCCGG	PITX1	ENSG00000069011	-0.041708426637141915	[236]	[119,291,284,268]	-1	hSpCas9	negative selection	8594148
135031265	135031288	5	+	27260156	PC3	viability	CCCTTGCTCACCCGCACGCGCGG	PITX1	ENSG00000069011	-0.2492603316566958	[916]	[535,568,1258,942]	-5	hSpCas9	negative selection	8658399
135031276	135031299	5	-	27260156	PC3	viability	ACCTCACCGAGCCGCGCGTGCGG	PITX1	ENSG00000069011	0.10984266267586971	[499]	[265,565,848,671]	2	hSpCas9	negative selection	8658400
135028837	135028860	5	-	27260156	PATU8988T	viability	TCCAAACAGCACTCGTCGTTTGG	PITX1	ENSG00000069011	0.4633685669719738	[1134]	[1678,1646,1274,1458]	7	hSpCas9	negative selection	8715398
135029191	135029214	5	-	27260156	PATU8988T	viability	TACGAGGACGTGTACGCCGCCGG	PITX1	ENSG00000069011	0.0259493981205402	[236]	[312,207,157,253]	0	hSpCas9	negative selection	8715399
135031265	135031288	5	+	27260156	PATU8988T	viability	CCCTTGCTCACCCGCACGCGCGG	PITX1	ENSG00000069011	0.17269076602127698	[916]	[976,1244,933,850]	3	hSpCas9	negative selection	8779650
135031276	135031299	5	-	27260156	PATU8988T	viability	ACCTCACCGAGCCGCGCGTGCGG	PITX1	ENSG00000069011	0.5418219942437872	[499]	[690,972,530,640]	8	hSpCas9	negative selection	8779651
135028837	135028860	5	-	27260156	T47D	viability	TCCAAACAGCACTCGTCGTTTGG	PITX1	ENSG00000069011	0.2818555038903918	[1134]	[1504,1467,1824,1640]	6	hSpCas9	negative selection	8836649
135029191	135029214	5	-	27260156	T47D	viability	TACGAGGACGTGTACGCCGCCGG	PITX1	ENSG00000069011	-0.38169241731908365	[236]	[242,138,245,225]	-7	hSpCas9	negative selection	8836650
135031265	135031288	5	+	27260156	T47D	viability	CCCTTGCTCACCCGCACGCGCGG	PITX1	ENSG00000069011	-0.2152318364484811	[916]	[865,826,993,1002]	-5	hSpCas9	negative selection	8900901
135031276	135031299	5	-	27260156	T47D	viability	ACCTCACCGAGCCGCGCGTGCGG	PITX1	ENSG00000069011	0.11511057027352083	[499]	[655,581,621,668]	2	hSpCas9	negative selection	8900902
135028837	135028860	5	-	27260156	SU8686	viability	TCCAAACAGCACTCGTCGTTTGG	PITX1	ENSG00000069011	0.5951634722297734	[1134]	[1478,1561,1653,2217]	8	hSpCas9	negative selection	8957900
135029191	135029214	5	-	27260156	SU8686	viability	TACGAGGACGTGTACGCCGCCGG	PITX1	ENSG00000069011	-0.24680140813571572	[236]	[173,178,153,304]	-4	hSpCas9	negative selection	8957901
135031265	135031288	5	+	27260156	SU8686	viability	CCCTTGCTCACCCGCACGCGCGG	PITX1	ENSG00000069011	-0.14630715144224227	[916]	[773,727,826,996]	-3	hSpCas9	negative selection	9022152
135031276	135031299	5	-	27260156	SU8686	viability	ACCTCACCGAGCCGCGCGTGCGG	PITX1	ENSG00000069011	0.2880954147694626	[499]	[447,605,657,746]	5	hSpCas9	negative selection	9022153
135028837	135028860	5	-	27260156	SKES1	viability	TCCAAACAGCACTCGTCGTTTGG	PITX1	ENSG00000069011	0.40764991597640376	[1134]	[1769,1674,1410,1227]	8	hSpCas9	negative selection	9079151
135029191	135029214	5	-	27260156	SKES1	viability	TACGAGGACGTGTACGCCGCCGG	PITX1	ENSG00000069011	0.044194106063660255	[236]	[241,254,266,212]	1	hSpCas9	negative selection	9079152
135031265	135031288	5	+	27260156	SKES1	viability	CCCTTGCTCACCCGCACGCGCGG	PITX1	ENSG00000069011	-0.052525298735504045	[916]	[945,949,910,744]	-1	hSpCas9	negative selection	9143403
135031276	135031299	5	-	27260156	SKES1	viability	ACCTCACCGAGCCGCGCGTGCGG	PITX1	ENSG00000069011	0.3687269529497244	[499]	[764,896,513,463]	7	hSpCas9	negative selection	9143404
135028837	135028860	5	-	27260156	TOV112D	viability	TCCAAACAGCACTCGTCGTTTGG	PITX1	ENSG00000069011	0.46251322685354657	[1134]	[2013,1726,1352,1254]	8	hSpCas9	negative selection	9200402
135029191	135029214	5	-	27260156	TOV112D	viability	TACGAGGACGTGTACGCCGCCGG	PITX1	ENSG00000069011	-0.5809773727125729	[236]	[112,212,195,122]	-8	hSpCas9	negative selection	9200403
135031265	135031288	5	+	27260156	TOV112D	viability	CCCTTGCTCACCCGCACGCGCGG	PITX1	ENSG00000069011	0.003079713317186039	[916]	[841,828,1279,705]	0	hSpCas9	negative selection	9264654
135031276	135031299	5	-	27260156	TOV112D	viability	ACCTCACCGAGCCGCGCGTGCGG	PITX1	ENSG00000069011	0.07967351452399012	[499]	[420,553,646,491]	1	hSpCas9	negative selection	9264655
135028837	135028860	5	-	27260156	TC71	viability	TCCAAACAGCACTCGTCGTTTGG	PITX1	ENSG00000069011	0.3770355030570043	[1134]	[1530,1590,1476,1734]	8	hSpCas9	negative selection	9321653
135029191	135029214	5	-	27260156	TC71	viability	TACGAGGACGTGTACGCCGCCGG	PITX1	ENSG00000069011	-0.1479736001212717	[236]	[199,217,233,267]	-4	hSpCas9	negative selection	9321654
135031265	135031288	5	+	27260156	TC71	viability	CCCTTGCTCACCCGCACGCGCGG	PITX1	ENSG00000069011	-0.02898601043058302	[916]	[794,974,991,1102]	0	hSpCas9	negative selection	9385905
135031276	135031299	5	-	27260156	TC71	viability	ACCTCACCGAGCCGCGCGTGCGG	PITX1	ENSG00000069011	0.16560498510773464	[499]	[580,486,609,734]	4	hSpCas9	negative selection	9385906
135028837	135028860	5	-	27260156	TC32	viability	TCCAAACAGCACTCGTCGTTTGG	PITX1	ENSG00000069011	0.39560703100000993	[1134]	[1188,1124,1690,1723]	7	hSpCas9	negative selection	9442904
135029191	135029214	5	-	27260156	TC32	viability	TACGAGGACGTGTACGCCGCCGG	PITX1	ENSG00000069011	-0.14830142217918896	[236]	[182,146,179,306]	-3	hSpCas9	negative selection	9442905
135031265	135031288	5	+	27260156	TC32	viability	CCCTTGCTCACCCGCACGCGCGG	PITX1	ENSG00000069011	0.06597946195907822	[916]	[812,794,1166,872]	1	hSpCas9	negative selection	9507156
135031276	135031299	5	-	27260156	TC32	viability	ACCTCACCGAGCCGCGCGTGCGG	PITX1	ENSG00000069011	0.4034991751347146	[499]	[505,509,922,618]	7	hSpCas9	negative selection	9507157
135028899	135028922	5	+	27869803	HPAFII	viability after 27 days	CCGGTAGACGCTGTAGGGCGAGG	PITX1	ENSG00000069011	1.230938205362566	[262]	[323,324,NaN]	8	hSpCas9	negative selection	9590011
135029240	135029263	5	+	27869803	HPAFII	viability after 27 days	GCACGTAGCCACCCTTGCACAGG	PITX1	ENSG00000069011	-1.2099230693742316	[395]	[173,19,NaN]	-7	hSpCas9	negative selection	9590012
135031496	135031519	5	-	27869803	HPAFII	viability after 27 days	CCTACTGCAGAGAAGGAGCGCGG	PITX1	ENSG00000069011	-0.8231012197846292	[252]	[0,136,NaN]	-5	hSpCas9	negative selection	9590013
135031503	135031526	5	-	27869803	HPAFII	viability after 27 days	CGTCCTGCCTACTGCAGAGAAGG	PITX1	ENSG00000069011	-0.9847568491308809	[578]	[191,121,NaN]	-6	hSpCas9	negative selection	9590014
135028899	135028922	5	+	27869803	HPAFII	viability after 15 days	CCGGTAGACGCTGTAGGGCGAGG	PITX1	ENSG00000069011	0.4812078799890789	[262]	[499,328,NaN]	5	hSpCas9	negative selection	9672460
135029240	135029263	5	+	27869803	HPAFII	viability after 15 days	GCACGTAGCCACCCTTGCACAGG	PITX1	ENSG00000069011	-0.39011771748781954	[395]	[563,175,NaN]	-4	hSpCas9	negative selection	9672461
135031496	135031519	5	-	27869803	HPAFII	viability after 15 days	CCTACTGCAGAGAAGGAGCGCGG	PITX1	ENSG00000069011	-0.30928560599971217	[252]	[113,284,NaN]	-3	hSpCas9	negative selection	9672462
135031503	135031526	5	-	27869803	HPAFII	viability after 15 days	CGTCCTGCCTACTGCAGAGAAGG	PITX1	ENSG00000069011	-0.5567233052377617	[578]	[554,340,NaN]	-6	hSpCas9	negative selection	9672463
135028899	135028922	5	+	27869803	ASPC1	viability after 36 days	CCGGTAGACGCTGTAGGGCGAGG	PITX1	ENSG00000069011	0.5106587459173728	[448]	[180,407,103]	5	hSpCas9	negative selection	9754909
135029240	135029263	5	+	27869803	ASPC1	viability after 36 days	GCACGTAGCCACCCTTGCACAGG	PITX1	ENSG00000069011	0.034547473901216486	[1061]	[108,610,381]	0	hSpCas9	negative selection	9754910
135031496	135031519	5	-	27869803	ASPC1	viability after 36 days	CCTACTGCAGAGAAGGAGCGCGG	PITX1	ENSG00000069011	-0.10120640154039873	[435]	[84,9,284]	-1	hSpCas9	negative selection	9754911
135031503	135031526	5	-	27869803	ASPC1	viability after 36 days	CGTCCTGCCTACTGCAGAGAAGG	PITX1	ENSG00000069011	0.25252026100873737	[1330]	[870,468,391]	2	hSpCas9	negative selection	9754912
135028899	135028922	5	+	27869803	PATU8988S	viability after 35 days	CCGGTAGACGCTGTAGGGCGAGG	PITX1	ENSG00000069011	0.7566307289222812	[371]	[310,194,NaN]	7	hSpCas9	negative selection	9837358
135029240	135029263	5	+	27869803	PATU8988S	viability after 35 days	GCACGTAGCCACCCTTGCACAGG	PITX1	ENSG00000069011	0.5518157339985088	[929]	[581,515,NaN]	6	hSpCas9	negative selection	9837359
135031496	135031519	5	-	27869803	PATU8988S	viability after 35 days	CCTACTGCAGAGAAGGAGCGCGG	PITX1	ENSG00000069011	0.13423827800569457	[433]	[120,262,NaN]	1	hSpCas9	negative selection	9837360
135031503	135031526	5	-	27869803	PATU8988S	viability after 35 days	CGTCCTGCCTACTGCAGAGAAGG	PITX1	ENSG00000069011	0.913486712873183	[1183]	[767,1028,NaN]	8	hSpCas9	negative selection	9837361
135028899	135028922	5	+	27869803	PATU8988S	viability after 31 days	CCGGTAGACGCTGTAGGGCGAGG	PITX1	ENSG00000069011	0.915153594164094	[371]	[284,272,NaN]	8	hSpCas9	negative selection	9919807
135029240	135029263	5	+	27869803	PATU8988S	viability after 31 days	GCACGTAGCCACCCTTGCACAGG	PITX1	ENSG00000069011	0.2823494012431411	[929]	[428,478,NaN]	3	hSpCas9	negative selection	9919808
135031496	135031519	5	-	27869803	PATU8988S	viability after 31 days	CCTACTGCAGAGAAGGAGCGCGG	PITX1	ENSG00000069011	0.6801572376150357	[433]	[121,474,NaN]	7	hSpCas9	negative selection	9919809
135031503	135031526	5	-	27869803	PATU8988S	viability after 31 days	CGTCCTGCCTACTGCAGAGAAGG	PITX1	ENSG00000069011	0.5765801982535939	[1183]	[634,791,NaN]	7	hSpCas9	negative selection	9919810
135028899	135028922	5	+	27869803	HPAFII	viability after 35 days	CCGGTAGACGCTGTAGGGCGAGG	PITX1	ENSG00000069011	1.5809112979923943	[262]	[426,365,NaN]	9	hSpCas9	negative selection	10002256
135029240	135029263	5	+	27869803	HPAFII	viability after 35 days	GCACGTAGCCACCCTTGCACAGG	PITX1	ENSG00000069011	-1.645398195143428	[395]	[112,8,NaN]	-7	hSpCas9	negative selection	10002257
135031496	135031519	5	-	27869803	HPAFII	viability after 35 days	CCTACTGCAGAGAAGGAGCGCGG	PITX1	ENSG00000069011	-0.0009495720100164487	[252]	[0,270,NaN]	0	hSpCas9	negative selection	10002258
135031503	135031526	5	-	27869803	HPAFII	viability after 35 days	CGTCCTGCCTACTGCAGAGAAGG	PITX1	ENSG00000069011	-1.069106038239928	[578]	[134,144,NaN]	-6	hSpCas9	negative selection	10002259
135028899	135028922	5	+	27869803	HPAFII	viability after 31 days	CCGGTAGACGCTGTAGGGCGAGG	PITX1	ENSG00000069011	1.277951319906069	[262]	[411,298,NaN]	8	hSpCas9	negative selection	10084705
135029240	135029263	5	+	27869803	HPAFII	viability after 31 days	GCACGTAGCCACCCTTGCACAGG	PITX1	ENSG00000069011	-2.4903796308189223	[395]	[62,13,NaN]	-8	hSpCas9	negative selection	10084706
135031496	135031519	5	-	27869803	HPAFII	viability after 31 days	CCTACTGCAGAGAAGGAGCGCGG	PITX1	ENSG00000069011	-0.4967261981328106	[252]	[2,206,NaN]	-3	hSpCas9	negative selection	10084707
135031503	135031526	5	-	27869803	HPAFII	viability after 31 days	CGTCCTGCCTACTGCAGAGAAGG	PITX1	ENSG00000069011	-1.1729072911990976	[578]	[157,128,NaN]	-6	hSpCas9	negative selection	10084708
135031493	135031516	5	-	28162770	P31FUJ	viability	ACTGCAGAGAAGGAGCGCGGCGG	PITX1	ENSG00000069011	0.15222272579802532	[84]	[110]	1	hSpCas9	negative selection	10211727
135031461	135031484	5	-	28162770	P31FUJ	viability	GGGGCCCGAGGACAGTGGTGCGG	PITX1	ENSG00000069011	-0.42707102483643855	[253]	[221]	-4	hSpCas9	negative selection	10211728
135031408	135031431	5	-	28162770	P31FUJ	viability	CAGCCAAGAAGAAGAAGCAGCGG	PITX1	ENSG00000069011	0.5249968931689932	[164]	[278]	6	hSpCas9	negative selection	10211729
135031362	135031385	5	-	28162770	P31FUJ	viability	CCAGCAGTTGCAAGAGCTAGAGG	PITX1	ENSG00000069011	0.6164663593766198	[251]	[453]	7	hSpCas9	negative selection	10211730
135031493	135031516	5	-	28162770	TF1	viability	ACTGCAGAGAAGGAGCGCGGCGG	PITX1	ENSG00000069011	NaN	[NaN]	[53]	1	hSpCas9	negative selection	10381093
135031461	135031484	5	-	28162770	TF1	viability	GGGGCCCGAGGACAGTGGTGCGG	PITX1	ENSG00000069011	NaN	[NaN]	[110]	1	hSpCas9	negative selection	10381094
135031408	135031431	5	-	28162770	TF1	viability	CAGCCAAGAAGAAGAAGCAGCGG	PITX1	ENSG00000069011	NaN	[NaN]	[151]	1	hSpCas9	negative selection	10381095
135031362	135031385	5	-	28162770	TF1	viability	CCAGCAGTTGCAAGAGCTAGAGG	PITX1	ENSG00000069011	NaN	[NaN]	[145]	1	hSpCas9	negative selection	10381096
135031493	135031516	5	-	28162770	SKM1	viability	ACTGCAGAGAAGGAGCGCGGCGG	PITX1	ENSG00000069011	0.014499569695115122	[13]	[24]	0	hSpCas9	negative selection	10550459
135031461	135031484	5	-	28162770	SKM1	viability	GGGGCCCGAGGACAGTGGTGCGG	PITX1	ENSG00000069011	0.6171099362356959	[51]	[140]	6	hSpCas9	negative selection	10550460
135031408	135031431	5	-	28162770	SKM1	viability	CAGCCAAGAAGAAGAAGCAGCGG	PITX1	ENSG00000069011	0.11211036632153742	[55]	[106]	1	hSpCas9	negative selection	10550461
135031362	135031385	5	-	28162770	SKM1	viability	CCAGCAGTTGCAAGAGCTAGAGG	PITX1	ENSG00000069011	1.6254572789492159	[43]	[239]	9	hSpCas9	negative selection	10550462
135031493	135031516	5	-	28162770	SKM1	viability	ACTGCAGAGAAGGAGCGCGGCGG	PITX1	ENSG00000069011	0.014499569695115122	[13]	[24]	0	hSpCas9	negative selection	10719825
135031461	135031484	5	-	28162770	SKM1	viability	GGGGCCCGAGGACAGTGGTGCGG	PITX1	ENSG00000069011	0.6171099362356959	[51]	[140]	6	hSpCas9	negative selection	10719826
135031408	135031431	5	-	28162770	SKM1	viability	CAGCCAAGAAGAAGAAGCAGCGG	PITX1	ENSG00000069011	0.11211036632153742	[55]	[106]	1	hSpCas9	negative selection	10719827
135031362	135031385	5	-	28162770	SKM1	viability	CCAGCAGTTGCAAGAGCTAGAGG	PITX1	ENSG00000069011	1.6254572789492159	[43]	[239]	9	hSpCas9	negative selection	10719828
135031493	135031516	5	-	28162770	PL21	viability	ACTGCAGAGAAGGAGCGCGGCGG	PITX1	ENSG00000069011	-0.3023607260398631	[84]	[29]	-2	hSpCas9	negative selection	10889191
135031461	135031484	5	-	28162770	PL21	viability	GGGGCCCGAGGACAGTGGTGCGG	PITX1	ENSG00000069011	0.8131164913800728	[152]	[116]	7	hSpCas9	negative selection	10889192
135031408	135031431	5	-	28162770	PL21	viability	CAGCCAAGAAGAAGAAGCAGCGG	PITX1	ENSG00000069011	-0.17470879467382483	[235]	[90]	-1	hSpCas9	negative selection	10889193
135031362	135031385	5	-	28162770	PL21	viability	CCAGCAGTTGCAAGAGCTAGAGG	PITX1	ENSG00000069011	1.4046783710129698	[150]	[173]	9	hSpCas9	negative selection	10889194
135031493	135031516	5	-	28162770	P31FUJ	viability	ACTGCAGAGAAGGAGCGCGGCGG	PITX1	ENSG00000069011	0.15222272579802532	[84]	[110]	1	hSpCas9	negative selection	11058557
135031461	135031484	5	-	28162770	P31FUJ	viability	GGGGCCCGAGGACAGTGGTGCGG	PITX1	ENSG00000069011	-0.42707102483643855	[253]	[221]	-4	hSpCas9	negative selection	11058558
135031408	135031431	5	-	28162770	P31FUJ	viability	CAGCCAAGAAGAAGAAGCAGCGG	PITX1	ENSG00000069011	0.5249968931689932	[164]	[278]	6	hSpCas9	negative selection	11058559
135031362	135031385	5	-	28162770	P31FUJ	viability	CCAGCAGTTGCAAGAGCTAGAGG	PITX1	ENSG00000069011	0.6164663593766198	[251]	[453]	7	hSpCas9	negative selection	11058560
135031493	135031516	5	-	28162770	OCIAML5	viability	ACTGCAGAGAAGGAGCGCGGCGG	PITX1	ENSG00000069011	0.16258020510040438	[48]	[98]	1	hSpCas9	negative selection	11227923
135031461	135031484	5	-	28162770	OCIAML5	viability	GGGGCCCGAGGACAGTGGTGCGG	PITX1	ENSG00000069011	0.35229192764218936	[91]	[211]	3	hSpCas9	negative selection	11227924
135031408	135031431	5	-	28162770	OCIAML5	viability	CAGCCAAGAAGAAGAAGCAGCGG	PITX1	ENSG00000069011	-0.1613946289717257	[113]	[183]	-1	hSpCas9	negative selection	11227925
135031362	135031385	5	-	28162770	OCIAML5	viability	CCAGCAGTTGCAAGAGCTAGAGG	PITX1	ENSG00000069011	0.4042731823957885	[89]	[214]	3	hSpCas9	negative selection	11227926
135031493	135031516	5	-	28162770	EOL1	viability	ACTGCAGAGAAGGAGCGCGGCGG	PITX1	ENSG00000069011	0.2499480583647019	[165]	[103]	2	hSpCas9	negative selection	11397289
135031461	135031484	5	-	28162770	EOL1	viability	GGGGCCCGAGGACAGTGGTGCGG	PITX1	ENSG00000069011	-1.7022349048452485	[209]	[33]	-8	hSpCas9	negative selection	11397290
135031408	135031431	5	-	28162770	EOL1	viability	CAGCCAAGAAGAAGAAGCAGCGG	PITX1	ENSG00000069011	0.23882229391446147	[377]	[234]	2	hSpCas9	negative selection	11397291
135031362	135031385	5	-	28162770	EOL1	viability	CCAGCAGTTGCAAGAGCTAGAGG	PITX1	ENSG00000069011	-0.1534547404307387	[227]	[107]	-1	hSpCas9	negative selection	11397292
135031493	135031516	5	-	28162770	MOLM13	viability	ACTGCAGAGAAGGAGCGCGGCGG	PITX1	ENSG00000069011	-0.5442853324015235	[118]	[58]	-3	hSpCas9	negative selection	11566655
135031461	135031484	5	-	28162770	MOLM13	viability	GGGGCCCGAGGACAGTGGTGCGG	PITX1	ENSG00000069011	-1.1774457371560592	[243]	[77]	-6	hSpCas9	negative selection	11566656
135031408	135031431	5	-	28162770	MOLM13	viability	CAGCCAAGAAGAAGAAGCAGCGG	PITX1	ENSG00000069011	1.4189797810636324	[239]	[463]	9	hSpCas9	negative selection	11566657
135031362	135031385	5	-	28162770	MOLM13	viability	CCAGCAGTTGCAAGAGCTAGAGG	PITX1	ENSG00000069011	-0.05877447861191008	[290]	[201]	0	hSpCas9	negative selection	11566658
135031493	135031516	5	-	28162770	HEL	viability	ACTGCAGAGAAGGAGCGCGGCGG	PITX1	ENSG00000069011	1.198128217338166	[114]	[168]	9	hSpCas9	negative selection	11736021
135031461	135031484	5	-	28162770	HEL	viability	GGGGCCCGAGGACAGTGGTGCGG	PITX1	ENSG00000069011	-0.07069822666960839	[222]	[135]	0	hSpCas9	negative selection	11736022
135031408	135031431	5	-	28162770	HEL	viability	CAGCCAAGAAGAAGAAGCAGCGG	PITX1	ENSG00000069011	-0.4095174051310668	[252]	[121]	-3	hSpCas9	negative selection	11736023
135031362	135031385	5	-	28162770	HEL	viability	CCAGCAGTTGCAAGAGCTAGAGG	PITX1	ENSG00000069011	0.20587497026833465	[221]	[163]	1	hSpCas9	negative selection	11736024
135031493	135031516	5	-	28162770	MV411	viability	ACTGCAGAGAAGGAGCGCGGCGG	PITX1	ENSG00000069011	-0.9590133266846512	[89]	[38]	-6	hSpCas9	negative selection	11905387
135031461	135031484	5	-	28162770	MV411	viability	GGGGCCCGAGGACAGTGGTGCGG	PITX1	ENSG00000069011	-1.407426963168537	[147]	[46]	-7	hSpCas9	negative selection	11905388
135031408	135031431	5	-	28162770	MV411	viability	CAGCCAAGAAGAAGAAGCAGCGG	PITX1	ENSG00000069011	-2.3202469585065453	[165]	[27]	-8	hSpCas9	negative selection	11905389
135031362	135031385	5	-	28162770	MV411	viability	CCAGCAGTTGCAAGAGCTAGAGG	PITX1	ENSG00000069011	0.3002894330485102	[133]	[138]	2	hSpCas9	negative selection	11905390
135031493	135031516	5	-	28162770	MONOMAC1	viability	ACTGCAGAGAAGGAGCGCGGCGG	PITX1	ENSG00000069011	-0.4111616524124011	[57]	[49]	-4	hSpCas9	negative selection	12074753
135031461	135031484	5	-	28162770	MONOMAC1	viability	GGGGCCCGAGGACAGTGGTGCGG	PITX1	ENSG00000069011	-0.7116100198893119	[89]	[62]	-5	hSpCas9	negative selection	12074754
135031408	135031431	5	-	28162770	MONOMAC1	viability	CAGCCAAGAAGAAGAAGCAGCGG	PITX1	ENSG00000069011	0.6602979240747326	[153]	[278]	6	hSpCas9	negative selection	12074755
135031362	135031385	5	-	28162770	MONOMAC1	viability	CCAGCAGTTGCAAGAGCTAGAGG	PITX1	ENSG00000069011	0.3512671830827543	[92]	[135]	3	hSpCas9	negative selection	12074756
135031493	135031516	5	-	28162770	OCIAML2	viability	ACTGCAGAGAAGGAGCGCGGCGG	PITX1	ENSG00000069011	-1.778752120604493	[25]	[41]	-8	hSpCas9	negative selection	12244119
135031461	135031484	5	-	28162770	OCIAML2	viability	GGGGCCCGAGGACAGTGGTGCGG	PITX1	ENSG00000069011	-0.9770903522845996	[37]	[106]	-6	hSpCas9	negative selection	12244120
135031408	135031431	5	-	28162770	OCIAML2	viability	CAGCCAAGAAGAAGAAGCAGCGG	PITX1	ENSG00000069011	-0.44004150540873815	[34]	[142]	-3	hSpCas9	negative selection	12244121
135031362	135031385	5	-	28162770	OCIAML2	viability	CCAGCAGTTGCAAGAGCTAGAGG	PITX1	ENSG00000069011	-0.6910198936674613	[29]	[102]	-5	hSpCas9	negative selection	12244122
135031493	135031516	5	-	28162770	OCIAML3	viability	ACTGCAGAGAAGGAGCGCGGCGG	PITX1	ENSG00000069011	1.3878450129655773	[9]	[78]	9	hSpCas9	negative selection	12413485
135031461	135031484	5	-	28162770	OCIAML3	viability	GGGGCCCGAGGACAGTGGTGCGG	PITX1	ENSG00000069011	-1.0009172587196067	[58]	[88]	-6	hSpCas9	negative selection	12413486
135031408	135031431	5	-	28162770	OCIAML3	viability	CAGCCAAGAAGAAGAAGCAGCGG	PITX1	ENSG00000069011	0.90849270020502	[32]	[186]	7	hSpCas9	negative selection	12413487
135031362	135031385	5	-	28162770	OCIAML3	viability	CCAGCAGTTGCAAGAGCTAGAGG	PITX1	ENSG00000069011	0.43993969159917456	[62]	[257]	4	hSpCas9	negative selection	12413488