| 81202613 | 81202636 | 16 | - | 26627737 | DLD1 | viability | GGTGACCGTGCGAGACAAGATGG | PKD1L2 | ENSG00000166473 | 0.15672198043337082 | [156] | [47,64,51] | 1 | hSpCas9 | negative selection | 795546 | 81207571 | 81207594 | 16 | - | 26627737 | DLD1 | viability | ATGTCACCATCTCCCTGACGTGG | PKD1L2 | ENSG00000166473 | -0.21301333804393963 | [752] | [167,292,158] | -2 | hSpCas9 | negative selection | 795547 | 81208554 | 81208577 | 16 | + | 26627737 | DLD1 | viability | AGGTCTCATCTGCTGCCACCTGG | PKD1L2 | ENSG00000166473 | 0.6368401119838989 | [61] | [47,42,3] | 6 | hSpCas9 | negative selection | 795548 | 81215069 | 81215092 | 16 | + | 26627737 | DLD1 | viability | CGGCATCCTGGGTGCAGAAATGG | PKD1L2 | ENSG00000166473 | 0.09801812263331233 | [1798] | [548,830,457] | 1 | hSpCas9 | negative selection | 795549 | 81216360 | 81216383 | 16 | - | 26627737 | DLD1 | viability | CCAATGTGACCTACAGCAACTGG | PKD1L2 | ENSG00000166473 | 0.30772825131854553 | [2011] | [714,586,991] | 3 | hSpCas9 | negative selection | 795550 | 81220069 | 81220092 | 16 | - | 26627737 | DLD1 | viability | GCACGGAATGGAACCACGGAGGG | PKD1L2 | ENSG00000166473 | 0.8094771968438398 | [433] | [312,264,149] | 7 | hSpCas9 | negative selection | 795551 | 81202613 | 81202636 | 16 | - | 26627737 | GBM cells | viability after 5 days | GGTGACCGTGCGAGACAAGATGG | PKD1L2 | ENSG00000166473 | -0.06044414061696868 | [69] | [26,44] | -1 | hSpCas9 | negative selection | 877861 | 81207571 | 81207594 | 16 | - | 26627737 | GBM cells | viability after 5 days | ATGTCACCATCTCCCTGACGTGG | PKD1L2 | ENSG00000166473 | -0.002021997585211821 | [407] | [227,208] | 0 | hSpCas9 | negative selection | 877862 | 81208554 | 81208577 | 16 | + | 26627737 | GBM cells | viability after 5 days | AGGTCTCATCTGCTGCCACCTGG | PKD1L2 | ENSG00000166473 | 0.2774254981394155 | [49] | [32,31] | 4 | hSpCas9 | negative selection | 877863 | 81215069 | 81215092 | 16 | + | 26627737 | GBM cells | viability after 5 days | CGGCATCCTGGGTGCAGAAATGG | PKD1L2 | ENSG00000166473 | 0.41501451746203744 | [943] | [692,656] | 6 | hSpCas9 | negative selection | 877864 | 81216360 | 81216383 | 16 | - | 26627737 | GBM cells | viability after 5 days | CCAATGTGACCTACAGCAACTGG | PKD1L2 | ENSG00000166473 | 0.1589767141881886 | [890] | [512,553] | 2 | hSpCas9 | negative selection | 877865 | 81220069 | 81220092 | 16 | - | 26627737 | GBM cells | viability after 5 days | GCACGGAATGGAACCACGGAGGG | PKD1L2 | ENSG00000166473 | 0.6538013770491541 | [287] | [262,222] | 8 | hSpCas9 | negative selection | 877866 | 81202613 | 81202636 | 16 | - | 26627737 | GBM cells | viability after 13 days | GGTGACCGTGCGAGACAAGATGG | PKD1L2 | ENSG00000166473 | 0.5318634776093434 | [69] | [87,27] | 6 | hSpCas9 | negative selection | 960176 | 81207571 | 81207594 | 16 | - | 26627737 | GBM cells | viability after 13 days | ATGTCACCATCTCCCTGACGTGG | PKD1L2 | ENSG00000166473 | -0.02067880805782296 | [407] | [247,193] | 0 | hSpCas9 | negative selection | 960177 | 81208554 | 81208577 | 16 | + | 26627737 | GBM cells | viability after 13 days | AGGTCTCATCTGCTGCCACCTGG | PKD1L2 | ENSG00000166473 | 0.8989769421428435 | [49] | [54,46] | 9 | hSpCas9 | negative selection | 960178 | 81215069 | 81215092 | 16 | + | 26627737 | GBM cells | viability after 13 days | CGGCATCCTGGGTGCAGAAATGG | PKD1L2 | ENSG00000166473 | 0.6364444707480064 | [943] | [927,688] | 7 | hSpCas9 | negative selection | 960179 | 81216360 | 81216383 | 16 | - | 26627737 | GBM cells | viability after 13 days | CCAATGTGACCTACAGCAACTGG | PKD1L2 | ENSG00000166473 | 0.23676464683282195 | [890] | [642,509] | 3 | hSpCas9 | negative selection | 960180 | 81220069 | 81220092 | 16 | - | 26627737 | GBM cells | viability after 13 days | GCACGGAATGGAACCACGGAGGG | PKD1L2 | ENSG00000166473 | 0.6293746699129313 | [287] | [308,186] | 7 | hSpCas9 | negative selection | 960181 | 81202613 | 81202636 | 16 | - | 26627737 | GBM cells | viability after 21 days | GGTGACCGTGCGAGACAAGATGG | PKD1L2 | ENSG00000166473 | 0.3251863767987895 | [69] | [55,39] | 3 | hSpCas9 | negative selection | 1042491 | 81207571 | 81207594 | 16 | - | 26627737 | GBM cells | viability after 21 days | ATGTCACCATCTCCCTGACGTGG | PKD1L2 | ENSG00000166473 | 0.6450282971913013 | [407] | [378,316] | 6 | hSpCas9 | negative selection | 1042492 | 81208554 | 81208577 | 16 | + | 26627737 | GBM cells | viability after 21 days | AGGTCTCATCTGCTGCCACCTGG | PKD1L2 | ENSG00000166473 | 1.5732555461942677 | [49] | [72,87] | 9 | hSpCas9 | negative selection | 1042493 | 81215069 | 81215092 | 16 | + | 26627737 | GBM cells | viability after 21 days | CGGCATCCTGGGTGCAGAAATGG | PKD1L2 | ENSG00000166473 | 0.8202495928173068 | [943] | [915,895] | 7 | hSpCas9 | negative selection | 1042494 | 81216360 | 81216383 | 16 | - | 26627737 | GBM cells | viability after 21 days | CCAATGTGACCTACAGCAACTGG | PKD1L2 | ENSG00000166473 | -0.013026276375223134 | [890] | [509,451] | 0 | hSpCas9 | negative selection | 1042495 | 81220069 | 81220092 | 16 | - | 26627737 | GBM cells | viability after 21 days | GCACGGAATGGAACCACGGAGGG | PKD1L2 | ENSG00000166473 | 1.060609086478543 | [287] | [317,333] | 9 | hSpCas9 | negative selection | 1042496 | 81202613 | 81202636 | 16 | - | 26627737 | RPE1 | viability after 9 days | GGTGACCGTGCGAGACAAGATGG | PKD1L2 | ENSG00000166473 | 2.9476139510192705 | [55] | [105,172] | 9 | hSpCas9 | negative selection | 1124806 | 81207571 | 81207594 | 16 | - | 26627737 | RPE1 | viability after 9 days | ATGTCACCATCTCCCTGACGTGG | PKD1L2 | ENSG00000166473 | 1.6331366236022824 | [403] | [242,584] | 8 | hSpCas9 | negative selection | 1124807 | 81208554 | 81208577 | 16 | + | 26627737 | RPE1 | viability after 9 days | AGGTCTCATCTGCTGCCACCTGG | PKD1L2 | ENSG00000166473 | 0.09625379925425048 | [238] | [10,168] | 0 | hSpCas9 | negative selection | 1124808 | 81215069 | 81215092 | 16 | + | 26627737 | RPE1 | viability after 9 days | CGGCATCCTGGGTGCAGAAATGG | PKD1L2 | ENSG00000166473 | 0.4133752533209991 | [4660] | [1821,2099] | 3 | hSpCas9 | negative selection | 1124809 | 81216360 | 81216383 | 16 | - | 26627737 | RPE1 | viability after 9 days | CCAATGTGACCTACAGCAACTGG | PKD1L2 | ENSG00000166473 | -0.5147327423958936 | [4124] | [940,855] | -4 | hSpCas9 | negative selection | 1124810 | 81220069 | 81220092 | 16 | - | 26627737 | RPE1 | viability after 9 days | GCACGGAATGGAACCACGGAGGG | PKD1L2 | ENSG00000166473 | 0.7139500839780525 | [690] | [370,333] | 5 | hSpCas9 | negative selection | 1124811 | 81202613 | 81202636 | 16 | - | 26627737 | RPE1 | viability after 12 days | GGTGACCGTGCGAGACAAGATGG | PKD1L2 | ENSG00000166473 | 2.3693947139202454 | [55] | [68,86] | 9 | hSpCas9 | negative selection | 1207121 | 81207571 | 81207594 | 16 | - | 26627737 | RPE1 | viability after 12 days | ATGTCACCATCTCCCTGACGTGG | PKD1L2 | ENSG00000166473 | 1.4706977133073793 | [403] | [260,342] | 7 | hSpCas9 | negative selection | 1207122 | 81208554 | 81208577 | 16 | + | 26627737 | RPE1 | viability after 12 days | AGGTCTCATCTGCTGCCACCTGG | PKD1L2 | ENSG00000166473 | -0.42237143968823077 | [238] | [27,68] | -3 | hSpCas9 | negative selection | 1207123 | 81215069 | 81215092 | 16 | + | 26627737 | RPE1 | viability after 12 days | CGGCATCCTGGGTGCAGAAATGG | PKD1L2 | ENSG00000166473 | 0.6216359413800521 | [4660] | [1934,1917] | 4 | hSpCas9 | negative selection | 1207124 | 81216360 | 81216383 | 16 | - | 26627737 | RPE1 | viability after 12 days | CCAATGTGACCTACAGCAACTGG | PKD1L2 | ENSG00000166473 | -0.7260497070022676 | [4124] | [601,741] | -5 | hSpCas9 | negative selection | 1207125 | 81220069 | 81220092 | 16 | - | 26627737 | RPE1 | viability after 12 days | GCACGGAATGGAACCACGGAGGG | PKD1L2 | ENSG00000166473 | 0.4349488333451115 | [690] | [181,323] | 3 | hSpCas9 | negative selection | 1207126 | 81202613 | 81202636 | 16 | - | 26627737 | RPE1 | viability after 15 days | GGTGACCGTGCGAGACAAGATGG | PKD1L2 | ENSG00000166473 | 2.862209512753906 | [55] | [160,70] | 9 | hSpCas9 | negative selection | 1289436 | 81207571 | 81207594 | 16 | - | 26627737 | RPE1 | viability after 15 days | ATGTCACCATCTCCCTGACGTGG | PKD1L2 | ENSG00000166473 | 0.5096198687914848 | [403] | [66,254] | 3 | hSpCas9 | negative selection | 1289437 | 81208554 | 81208577 | 16 | + | 26627737 | RPE1 | viability after 15 days | AGGTCTCATCTGCTGCCACCTGG | PKD1L2 | ENSG00000166473 | -0.6788180253203251 | [238] | [0,81] | -4 | hSpCas9 | negative selection | 1289438 | 81215069 | 81215092 | 16 | + | 26627737 | RPE1 | viability after 15 days | CGGCATCCTGGGTGCAGAAATGG | PKD1L2 | ENSG00000166473 | 0.5407478183091472 | [4660] | [2055,1784] | 3 | hSpCas9 | negative selection | 1289439 | 81216360 | 81216383 | 16 | - | 26627737 | RPE1 | viability after 15 days | CCAATGTGACCTACAGCAACTGG | PKD1L2 | ENSG00000166473 | -0.20534564953962153 | [4124] | [1120,906] | -1 | hSpCas9 | negative selection | 1289440 | 81220069 | 81220092 | 16 | - | 26627737 | RPE1 | viability after 15 days | GCACGGAATGGAACCACGGAGGG | PKD1L2 | ENSG00000166473 | 0.8021551378985159 | [690] | [377,304] | 5 | hSpCas9 | negative selection | 1289441 | 81202613 | 81202636 | 16 | - | 26627737 | RPE1 | viability after 18 days | GGTGACCGTGCGAGACAAGATGG | PKD1L2 | ENSG00000166473 | 1.9828081883534925 | [55] | [51,67] | 8 | hSpCas9 | negative selection | 1371751 | 81207571 | 81207594 | 16 | - | 26627737 | RPE1 | viability after 18 days | ATGTCACCATCTCCCTGACGTGG | PKD1L2 | ENSG00000166473 | 1.6345798920526096 | [403] | [280,399] | 8 | hSpCas9 | negative selection | 1371752 | 81208554 | 81208577 | 16 | + | 26627737 | RPE1 | viability after 18 days | AGGTCTCATCTGCTGCCACCTGG | PKD1L2 | ENSG00000166473 | -0.09737327145209695 | [238] | [24,97] | 0 | hSpCas9 | negative selection | 1371753 | 81215069 | 81215092 | 16 | + | 26627737 | RPE1 | viability after 18 days | CGGCATCCTGGGTGCAGAAATGG | PKD1L2 | ENSG00000166473 | 0.79283614088751 | [4660] | [2505,1829] | 5 | hSpCas9 | negative selection | 1371754 | 81216360 | 81216383 | 16 | - | 26627737 | RPE1 | viability after 18 days | CCAATGTGACCTACAGCAACTGG | PKD1L2 | ENSG00000166473 | -0.30906315899468995 | [4124] | [1030,756] | -2 | hSpCas9 | negative selection | 1371755 | 81220069 | 81220092 | 16 | - | 26627737 | RPE1 | viability after 18 days | GCACGGAATGGAACCACGGAGGG | PKD1L2 | ENSG00000166473 | 0.8359502350566377 | [690] | [299,367] | 5 | hSpCas9 | negative selection | 1371756 | 81202613 | 81202636 | 16 | - | 26627737 | HeLa | viability after 8 days | GGTGACCGTGCGAGACAAGATGG | PKD1L2 | ENSG00000166473 | 0.3037142401798867 | [96] | [39,66,46] | 3 | hSpCas9 | negative selection | 1454066 | 81207571 | 81207594 | 16 | - | 26627737 | HeLa | viability after 8 days | ATGTCACCATCTCCCTGACGTGG | PKD1L2 | ENSG00000166473 | 0.14149530854193926 | [743] | [510,278,317] | 1 | hSpCas9 | negative selection | 1454067 | 81208554 | 81208577 | 16 | + | 26627737 | HeLa | viability after 8 days | AGGTCTCATCTGCTGCCACCTGG | PKD1L2 | ENSG00000166473 | 0.32939137735046176 | [128] | [121,1,96] | 3 | hSpCas9 | negative selection | 1454068 | 81215069 | 81215092 | 16 | + | 26627737 | HeLa | viability after 8 days | CGGCATCCTGGGTGCAGAAATGG | PKD1L2 | ENSG00000166473 | 1.1021492616648774 | [1248] | [1651,1277,709] | 8 | hSpCas9 | negative selection | 1454069 | 81216360 | 81216383 | 16 | - | 26627737 | HeLa | viability after 8 days | CCAATGTGACCTACAGCAACTGG | PKD1L2 | ENSG00000166473 | 0.7309089012111771 | [1308] | [1168,796,920] | 6 | hSpCas9 | negative selection | 1454070 | 81220069 | 81220092 | 16 | - | 26627737 | HeLa | viability after 8 days | GCACGGAATGGAACCACGGAGGG | PKD1L2 | ENSG00000166473 | 0.4364544118475102 | [508] | [452,299,187] | 4 | hSpCas9 | negative selection | 1454071 | 81202613 | 81202636 | 16 | - | 26627737 | HeLa | viability after 12 days | GGTGACCGTGCGAGACAAGATGG | PKD1L2 | ENSG00000166473 | 0.3184371127640495 | [96] | [100,6,47] | 2 | hSpCas9 | negative selection | 1536381 | 81207571 | 81207594 | 16 | - | 26627737 | HeLa | viability after 12 days | ATGTCACCATCTCCCTGACGTGG | PKD1L2 | ENSG00000166473 | 0.05326987362248947 | [743] | [397,218,352] | 0 | hSpCas9 | negative selection | 1536382 | 81208554 | 81208577 | 16 | + | 26627737 | HeLa | viability after 12 days | AGGTCTCATCTGCTGCCACCTGG | PKD1L2 | ENSG00000166473 | -0.48225642721633233 | [128] | [4,61,43] | -4 | hSpCas9 | negative selection | 1536383 | 81215069 | 81215092 | 16 | + | 26627737 | HeLa | viability after 12 days | CGGCATCCTGGGTGCAGAAATGG | PKD1L2 | ENSG00000166473 | 0.6012913113121472 | [1248] | [541,916,868] | 5 | hSpCas9 | negative selection | 1536384 | 81216360 | 81216383 | 16 | - | 26627737 | HeLa | viability after 12 days | CCAATGTGACCTACAGCAACTGG | PKD1L2 | ENSG00000166473 | 0.6125828351547247 | [1308] | [961,697,838] | 5 | hSpCas9 | negative selection | 1536385 | 81220069 | 81220092 | 16 | - | 26627737 | HeLa | viability after 12 days | GCACGGAATGGAACCACGGAGGG | PKD1L2 | ENSG00000166473 | 0.30988771207960064 | [508] | [126,235,417] | 2 | hSpCas9 | negative selection | 1536386 | 81202613 | 81202636 | 16 | - | 26627737 | HeLa | viability after 15 days | GGTGACCGTGCGAGACAAGATGG | PKD1L2 | ENSG00000166473 | 1.5116029736730456 | [96] | [206,59,65] | 8 | hSpCas9 | negative selection | 1618696 | 81207571 | 81207594 | 16 | - | 26627737 | HeLa | viability after 15 days | ATGTCACCATCTCCCTGACGTGG | PKD1L2 | ENSG00000166473 | 0.3305028941817101 | [743] | [249,552,337] | 2 | hSpCas9 | negative selection | 1618697 | 81208554 | 81208577 | 16 | + | 26627737 | HeLa | viability after 15 days | AGGTCTCATCTGCTGCCACCTGG | PKD1L2 | ENSG00000166473 | -0.14693915333659735 | [128] | [31,68,40] | -1 | hSpCas9 | negative selection | 1618698 | 81215069 | 81215092 | 16 | + | 26627737 | HeLa | viability after 15 days | CGGCATCCTGGGTGCAGAAATGG | PKD1L2 | ENSG00000166473 | 0.8629162829664467 | [1248] | [1136,800,825] | 6 | hSpCas9 | negative selection | 1618699 | 81216360 | 81216383 | 16 | - | 26627737 | HeLa | viability after 15 days | CCAATGTGACCTACAGCAACTGG | PKD1L2 | ENSG00000166473 | 0.1305342173551136 | [1308] | [475,721,550] | 1 | hSpCas9 | negative selection | 1618700 | 81220069 | 81220092 | 16 | - | 26627737 | HeLa | viability after 15 days | GCACGGAATGGAACCACGGAGGG | PKD1L2 | ENSG00000166473 | 0.44985694009801347 | [508] | [320,239,287] | 4 | hSpCas9 | negative selection | 1618701 | 81202613 | 81202636 | 16 | - | 26627737 | HeLa | viability after 18 days | GGTGACCGTGCGAGACAAGATGG | PKD1L2 | ENSG00000166473 | 1.5593169614321014 | [96] | [149,44,65] | 8 | hSpCas9 | negative selection | 1701011 | 81207571 | 81207594 | 16 | - | 26627737 | HeLa | viability after 18 days | ATGTCACCATCTCCCTGACGTGG | PKD1L2 | ENSG00000166473 | 0.3377670054663313 | [743] | [164,465,337] | 3 | hSpCas9 | negative selection | 1701012 | 81208554 | 81208577 | 16 | + | 26627737 | HeLa | viability after 18 days | AGGTCTCATCTGCTGCCACCTGG | PKD1L2 | ENSG00000166473 | -0.06455160802264404 | [128] | [26,56,40] | 0 | hSpCas9 | negative selection | 1701013 | 81215069 | 81215092 | 16 | + | 26627737 | HeLa | viability after 18 days | CGGCATCCTGGGTGCAGAAATGG | PKD1L2 | ENSG00000166473 | 0.8531877885968926 | [1248] | [758,652,825] | 6 | hSpCas9 | negative selection | 1701014 | 81216360 | 81216383 | 16 | - | 26627737 | HeLa | viability after 18 days | CCAATGTGACCTACAGCAACTGG | PKD1L2 | ENSG00000166473 | 0.14565030329247208 | [1308] | [327,601,550] | 1 | hSpCas9 | negative selection | 1701015 | 81220069 | 81220092 | 16 | - | 26627737 | HeLa | viability after 18 days | GCACGGAATGGAACCACGGAGGG | PKD1L2 | ENSG00000166473 | 0.4431288647325593 | [508] | [206,205,287] | 3 | hSpCas9 | negative selection | 1701016 | 81202613 | 81202636 | 16 | - | 26627737 | HCT116 | viability after 6 days | GGTGACCGTGCGAGACAAGATGG | PKD1L2 | ENSG00000166473 | 2.466308097455015 | [205] | [109,216] | 9 | hSpCas9 | negative selection | 1783326 | 81207571 | 81207594 | 16 | - | 26627737 | HCT116 | viability after 6 days | ATGTCACCATCTCCCTGACGTGG | PKD1L2 | ENSG00000166473 | 0.12556790291117048 | [1372] | [190,259] | 0 | hSpCas9 | negative selection | 1783327 | 81208554 | 81208577 | 16 | + | 26627737 | HCT116 | viability after 6 days | AGGTCTCATCTGCTGCCACCTGG | PKD1L2 | ENSG00000166473 | 4.167645288650041 | [22] | [44,75] | 9 | hSpCas9 | negative selection | 1783328 | 81215069 | 81215092 | 16 | + | 26627737 | HCT116 | viability after 6 days | CGGCATCCTGGGTGCAGAAATGG | PKD1L2 | ENSG00000166473 | 0.5492827918908221 | [2557] | [572,596] | 3 | hSpCas9 | negative selection | 1783329 | 81216360 | 81216383 | 16 | - | 26627737 | HCT116 | viability after 6 days | CCAATGTGACCTACAGCAACTGG | PKD1L2 | ENSG00000166473 | 1.3476682992152675 | [1860] | [770,729] | 7 | hSpCas9 | negative selection | 1783330 | 81220069 | 81220092 | 16 | - | 26627737 | HCT116 | viability after 6 days | GCACGGAATGGAACCACGGAGGG | PKD1L2 | ENSG00000166473 | -0.8666729786906153 | [1176] | [56,125] | -5 | hSpCas9 | negative selection | 1783331 | 81202613 | 81202636 | 16 | - | 26627737 | HCT116 | viability after 8 days | GGTGACCGTGCGAGACAAGATGG | PKD1L2 | ENSG00000166473 | 0.12534765640093948 | [66] | [36,63,19] | 1 | hSpCas9 | negative selection | 1865641 | 81207571 | 81207594 | 16 | - | 26627737 | HCT116 | viability after 8 days | ATGTCACCATCTCCCTGACGTGG | PKD1L2 | ENSG00000166473 | -0.46348443957344054 | [743] | [348,173,368] | -5 | hSpCas9 | negative selection | 1865642 | 81208554 | 81208577 | 16 | + | 26627737 | HCT116 | viability after 8 days | AGGTCTCATCTGCTGCCACCTGG | PKD1L2 | ENSG00000166473 | -0.03460179336303515 | [70] | [54,30,28] | 0 | hSpCas9 | negative selection | 1865643 | 81215069 | 81215092 | 16 | + | 26627737 | HCT116 | viability after 8 days | CGGCATCCTGGGTGCAGAAATGG | PKD1L2 | ENSG00000166473 | 0.0655089531525026 | [1256] | [804,655,714] | 0 | hSpCas9 | negative selection | 1865644 | 81216360 | 81216383 | 16 | - | 26627737 | HCT116 | viability after 8 days | CCAATGTGACCTACAGCAACTGG | PKD1L2 | ENSG00000166473 | -0.2721827048603147 | [1045] | [300,511,613] | -3 | hSpCas9 | negative selection | 1865645 | 81220069 | 81220092 | 16 | - | 26627737 | HCT116 | viability after 8 days | GCACGGAATGGAACCACGGAGGG | PKD1L2 | ENSG00000166473 | -0.02572156598287134 | [392] | [140,208,285] | 0 | hSpCas9 | negative selection | 1865646 | 81202613 | 81202636 | 16 | - | 26627737 | HCT116 | viability after 9 days | GGTGACCGTGCGAGACAAGATGG | PKD1L2 | ENSG00000166473 | -0.6690359865713373 | [205] | [47,23] | -5 | hSpCas9 | negative selection | 1947956 | 81207571 | 81207594 | 16 | - | 26627737 | HCT116 | viability after 9 days | ATGTCACCATCTCCCTGACGTGG | PKD1L2 | ENSG00000166473 | 0.13908772514625034 | [1372] | [310,476] | 1 | hSpCas9 | negative selection | 1947957 | 81208554 | 81208577 | 16 | + | 26627737 | HCT116 | viability after 9 days | AGGTCTCATCTGCTGCCACCTGG | PKD1L2 | ENSG00000166473 | 0.809806891814461 | [22] | [12,8] | 6 | hSpCas9 | negative selection | 1947958 | 81215069 | 81215092 | 16 | + | 26627737 | HCT116 | viability after 9 days | CGGCATCCTGGGTGCAGAAATGG | PKD1L2 | ENSG00000166473 | -0.11096099129528358 | [2557] | [441,782] | 0 | hSpCas9 | negative selection | 1947959 | 81216360 | 81216383 | 16 | - | 26627737 | HCT116 | viability after 9 days | CCAATGTGACCTACAGCAACTGG | PKD1L2 | ENSG00000166473 | 0.9014725676368085 | [1860] | [987,880] | 6 | hSpCas9 | negative selection | 1947960 | 81220069 | 81220092 | 16 | - | 26627737 | HCT116 | viability after 9 days | GCACGGAATGGAACCACGGAGGG | PKD1L2 | ENSG00000166473 | -1.5245085529341902 | [1176] | [125,95] | -8 | hSpCas9 | negative selection | 1947961 | 81202613 | 81202636 | 16 | - | 26627737 | HCT116 | viability after 12 days | GGTGACCGTGCGAGACAAGATGG | PKD1L2 | ENSG00000166473 | 1.111155685533253 | [66] | [46,86,96] | 8 | hSpCas9 | negative selection | 2030271 | 81207571 | 81207594 | 16 | - | 26627737 | HCT116 | viability after 12 days | ATGTCACCATCTCCCTGACGTGG | PKD1L2 | ENSG00000166473 | -0.7550164072031885 | [743] | [270,248,171] | -7 | hSpCas9 | negative selection | 2030272 | 81208554 | 81208577 | 16 | + | 26627737 | HCT116 | viability after 12 days | AGGTCTCATCTGCTGCCACCTGG | PKD1L2 | ENSG00000166473 | 0.8867817236255782 | [70] | [125,28,45] | 7 | hSpCas9 | negative selection | 2030273 | 81215069 | 81215092 | 16 | + | 26627737 | HCT116 | viability after 12 days | CGGCATCCTGGGTGCAGAAATGG | PKD1L2 | ENSG00000166473 | 0.3177243101847198 | [1256] | [948,618,885] | 3 | hSpCas9 | negative selection | 2030274 | 81216360 | 81216383 | 16 | - | 26627737 | HCT116 | viability after 12 days | CCAATGTGACCTACAGCAACTGG | PKD1L2 | ENSG00000166473 | 0.03941533804748221 | [1045] | [571,475,643] | 0 | hSpCas9 | negative selection | 2030275 | 81220069 | 81220092 | 16 | - | 26627737 | HCT116 | viability after 12 days | GCACGGAATGGAACCACGGAGGG | PKD1L2 | ENSG00000166473 | -0.5044007213752125 | [392] | [158,202,74] | -5 | hSpCas9 | negative selection | 2030276 | 81202613 | 81202636 | 16 | - | 26627737 | HCT116 | viability after 15 days | GGTGACCGTGCGAGACAAGATGG | PKD1L2 | ENSG00000166473 | 0.49883993589071585 | [66] | [14,61,80] | 5 | hSpCas9 | negative selection | 2112586 | 81207571 | 81207594 | 16 | - | 26627737 | HCT116 | viability after 15 days | ATGTCACCATCTCCCTGACGTGG | PKD1L2 | ENSG00000166473 | -0.5039446077131806 | [743] | [353,144,409] | -5 | hSpCas9 | negative selection | 2112587 | 81208554 | 81208577 | 16 | + | 26627737 | HCT116 | viability after 15 days | AGGTCTCATCTGCTGCCACCTGG | PKD1L2 | ENSG00000166473 | -0.3109659895688468 | [70] | [74,17,10] | -3 | hSpCas9 | negative selection | 2112588 | 81215069 | 81215092 | 16 | + | 26627737 | HCT116 | viability after 15 days | CGGCATCCTGGGTGCAGAAATGG | PKD1L2 | ENSG00000166473 | 0.225260177081128 | [1256] | [905,772,859] | 2 | hSpCas9 | negative selection | 2112589 | 81216360 | 81216383 | 16 | - | 26627737 | HCT116 | viability after 15 days | CCAATGTGACCTACAGCAACTGG | PKD1L2 | ENSG00000166473 | 0.39193807595402896 | [1045] | [973,849,565] | 4 | hSpCas9 | negative selection | 2112590 | 81220069 | 81220092 | 16 | - | 26627737 | HCT116 | viability after 15 days | GCACGGAATGGAACCACGGAGGG | PKD1L2 | ENSG00000166473 | -0.12678770702241987 | [392] | [213,198,207] | -1 | hSpCas9 | negative selection | 2112591 | 81202613 | 81202636 | 16 | - | 26627737 | HCT116 | viability after 18 days | GGTGACCGTGCGAGACAAGATGG | PKD1L2 | ENSG00000166473 | 0.10677571662305096 | [66] | [2,61,37] | 0 | hSpCas9 | negative selection | 2194901 | 81207571 | 81207594 | 16 | - | 26627737 | HCT116 | viability after 18 days | ATGTCACCATCTCCCTGACGTGG | PKD1L2 | ENSG00000166473 | -0.579594939960591 | [743] | [358,106,265] | -5 | hSpCas9 | negative selection | 2194902 | 81208554 | 81208577 | 16 | + | 26627737 | HCT116 | viability after 18 days | AGGTCTCATCTGCTGCCACCTGG | PKD1L2 | ENSG00000166473 | -0.3298609606135554 | [70] | [51,7,22] | -3 | hSpCas9 | negative selection | 2194903 | 81215069 | 81215092 | 16 | + | 26627737 | HCT116 | viability after 18 days | CGGCATCCTGGGTGCAGAAATGG | PKD1L2 | ENSG00000166473 | 0.2778925305256408 | [1256] | [748,674,792] | 2 | hSpCas9 | negative selection | 2194904 | 81216360 | 81216383 | 16 | - | 26627737 | HCT116 | viability after 18 days | CCAATGTGACCTACAGCAACTGG | PKD1L2 | ENSG00000166473 | 0.5836617595658904 | [1045] | [1024,515,747] | 5 | hSpCas9 | negative selection | 2194905 | 81220069 | 81220092 | 16 | - | 26627737 | HCT116 | viability after 18 days | GCACGGAATGGAACCACGGAGGG | PKD1L2 | ENSG00000166473 | 0.07370269966642051 | [392] | [188,228,178] | 0 | hSpCas9 | negative selection | 2194906 | 81132428 | 81132451 | 16 | + | 25494202 | A375 | resistance to PLX-4720 (puromycin) | AGGCGGAGGTTGCAGTGAGCCGG | PKD1L2 | ENSG00000166473 | -1.3881494200540772 | [95,289] | [14,16] | -7 | dCas9-VP64 | positive selection | 2387316 | 81182583 | 81182606 | 16 | - | 25494202 | A375 | resistance to PLX-4720 (puromycin) | TCTTGCTCTTTCACCCAGGCCGG | PKD1L2 | ENSG00000166473 | -3.4752685797456295 | [670,81] | [9,2] | -9 | dCas9-VP64 | positive selection | 2390699 | 81133098 | 81133121 | 16 | + | 25494202 | A375 | resistance to PLX-4720 (puromycin) | CGTGCCACTGCACTCCAGCCTAG | PKD1L2 | ENSG00000166473 | 0.4846974014178431 | [92,26] | [27,6] | 2 | dCas9-VP64 | positive selection | 2390930 | 81135113 | 81135136 | 16 | + | 25494202 | A375 | resistance to PLX-4720 (puromycin) | TGTCTGAGGAGTTTTGTCTGCGG | PKD1L2 | ENSG00000166473 | 2.0612646572377713 | [465,362] | [642,96] | 7 | dCas9-VP64 | positive selection | 2402018 | 81210063 | 81210086 | 16 | + | 25494202 | A375 | resistance to PLX-4720 (puromycin) | TGCGCCACTGCACTCCAGCCAAG | PKD1L2 | ENSG00000166473 | 0.6031003623548207 | [86,54] | [14,31] | 2 | dCas9-VP64 | positive selection | 2416182 | 81181493 | 81181516 | 16 | + | 25494202 | A375 | resistance to PLX-4720 (puromycin) | AAAAAGATGGCCGGGAGCAGTGG | PKD1L2 | ENSG00000166473 | -1.9990403521916968 | [188,15] | [1,7] | -9 | dCas9-VP64 | positive selection | 2420140 | 81181440 | 81181463 | 16 | - | 25494202 | A375 | resistance to PLX-4720 (puromycin) | CAAGAACTCGCTCCCGAGGGAGG | PKD1L2 | ENSG00000166473 | 0.011427214064645863 | [25,6] | [4,0] | 0 | dCas9-VP64 | positive selection | 2420141 | 81181465 | 81181488 | 16 | + | 25494202 | A375 | resistance to PLX-4720 (puromycin) | CTATTAGTCACCACCGGAGCTGG | PKD1L2 | ENSG00000166473 | 1.471264877404176 | [60,451] | [30,295] | 5 | dCas9-VP64 | positive selection | 2420142 | 81208322 | 81208345 | 16 | + | 25494202 | A375 | resistance to PLX-4720 (puromycin) | CAGGCGTGAGCCACCGCGTCCAG | PKD1L2 | ENSG00000166473 | -0.7423063429264437 | [17,121] | [9,7] | -4 | dCas9-VP64 | positive selection | 2425688 | 81131524 | 81131547 | 16 | - | 25494202 | A375 | resistance to PLX-4720 (puromycin) | GGAGTCTCTCTCTGTCGCCCAGG | PKD1L2 | ENSG00000166473 | 1.6026852076585545 | [0,1] | [0,0] | 6 | dCas9-VP64 | positive selection | 2429639 | 81149396 | 81149419 | 16 | + | 25494202 | A375 | resistance to PLX-4720 (puromycin) | GAGATGGGTTTTCACCATGTTAG | PKD1L2 | ENSG00000166473 | 3.916189069033361 | [314,93] | [113,1282] | 9 | dCas9-VP64 | positive selection | 2433940 | 81104621 | 81104644 | 16 | - | 25494202 | A375 | resistance to PLX-4720 (puromycin) | CCCAGGCTGGAGTGCAGTGGCAG | PKD1L2 | ENSG00000166473 | -1.2921060931449064 | [66,2] | [3,0] | -7 | dCas9-VP64 | positive selection | 2435125 | 81118550 | 81118573 | 16 | + | 25494202 | A375 | resistance to PLX-4720 (puromycin) | CAGGAGAATCGCTTGAACCCTGG | PKD1L2 | ENSG00000166473 | -1.1949452889942442 | [147,110] | [6,17] | -7 | dCas9-VP64 | positive selection | 2450154 | 81121342 | 81121365 | 16 | + | 25494202 | A375 | resistance to PLX-4720 (puromycin) | GCCTGTAGTCCCAGCTACTCAAG | PKD1L2 | ENSG00000166473 | 0.4848717924049799 | [259,492] | [140,88] | 2 | dCas9-VP64 | positive selection | 2468631 | 81168408 | 81168431 | 16 | + | 25494202 | A375 | resistance to PLX-4720 (puromycin) | TGGATGGATGGATGGATGGATGG | PKD1L2 | ENSG00000166473 | 2.7644531499590617 | [51,2] | [77,0] | 8 | dCas9-VP64 | positive selection | 2471373 | 81132428 | 81132451 | 16 | + | 25494202 | A375 | resistance to PLX-4720 (zeocin) | AGGCGGAGGTTGCAGTGAGCCGG | PKD1L2 | ENSG00000166473 | -0.15452703381003985 | [117,34] | [33,11] | -1 | dCas9-VP64 | positive selection | 2482571 | 81182583 | 81182606 | 16 | - | 25494202 | A375 | resistance to PLX-4720 (zeocin) | TCTTGCTCTTTCACCCAGGCCGG | PKD1L2 | ENSG00000166473 | 0.8980088860596516 | [158,118] | [140,31] | 6 | dCas9-VP64 | positive selection | 2485954 | 81133098 | 81133121 | 16 | + | 25494202 | A375 | resistance to PLX-4720 (zeocin) | CGTGCCACTGCACTCCAGCCTAG | PKD1L2 | ENSG00000166473 | 0.6971910689480432 | [49,47] | [24,25] | 5 | dCas9-VP64 | positive selection | 2486185 | 81135113 | 81135136 | 16 | + | 25494202 | A375 | resistance to PLX-4720 (zeocin) | TGTCTGAGGAGTTTTGTCTGCGG | PKD1L2 | ENSG00000166473 | -0.37816309005783866 | [208,223] | [48,58] | -4 | dCas9-VP64 | positive selection | 2497273 | 81210063 | 81210086 | 16 | + | 25494202 | A375 | resistance to PLX-4720 (zeocin) | TGCGCCACTGCACTCCAGCCAAG | PKD1L2 | ENSG00000166473 | -0.5652196159145948 | [243,309] | [59,60] | -5 | dCas9-VP64 | positive selection | 2511437 | 81181493 | 81181516 | 16 | + | 25494202 | A375 | resistance to PLX-4720 (zeocin) | AAAAAGATGGCCGGGAGCAGTGG | PKD1L2 | ENSG00000166473 | -0.10557175277581828 | [152,60] | [50,14] | -1 | dCas9-VP64 | positive selection | 2515395 | 81181440 | 81181463 | 16 | - | 25494202 | A375 | resistance to PLX-4720 (zeocin) | CAAGAACTCGCTCCCGAGGGAGG | PKD1L2 | ENSG00000166473 | 1.1455525274712894 | [39,44] | [22,37] | 7 | dCas9-VP64 | positive selection | 2515396 | 81181465 | 81181488 | 16 | + | 25494202 | A375 | resistance to PLX-4720 (zeocin) | CTATTAGTCACCACCGGAGCTGG | PKD1L2 | ENSG00000166473 | 0.5736611546451357 | [235,70] | [66,82] | 4 | dCas9-VP64 | positive selection | 2515397 | 81208322 | 81208345 | 16 | + | 25494202 | A375 | resistance to PLX-4720 (zeocin) | CAGGCGTGAGCCACCGCGTCCAG | PKD1L2 | ENSG00000166473 | 0.04080549521603816 | [105,72] | [24,33] | 0 | dCas9-VP64 | positive selection | 2520943 | 81131524 | 81131547 | 16 | - | 25494202 | A375 | resistance to PLX-4720 (zeocin) | GGAGTCTCTCTCTGTCGCCCAGG | PKD1L2 | ENSG00000166473 | 0.31611073697098746 | [6,38] | [2,13] | 2 | dCas9-VP64 | positive selection | 2524894 | 81149396 | 81149419 | 16 | + | 25494202 | A375 | resistance to PLX-4720 (zeocin) | GAGATGGGTTTTCACCATGTTAG | PKD1L2 | ENSG00000166473 | 2.0642303287003654 | [37,60] | [95,40] | 8 | dCas9-VP64 | positive selection | 2529195 | 81104621 | 81104644 | 16 | - | 25494202 | A375 | resistance to PLX-4720 (zeocin) | CCCAGGCTGGAGTGCAGTGGCAG | PKD1L2 | ENSG00000166473 | 0.4307409852930557 | [33,0] | [13,0] | 3 | dCas9-VP64 | positive selection | 2530380 | 81118550 | 81118573 | 16 | + | 25494202 | A375 | resistance to PLX-4720 (zeocin) | CAGGAGAATCGCTTGAACCCTGG | PKD1L2 | ENSG00000166473 | 1.2597172262171965 | [381,372] | [459,141] | 7 | dCas9-VP64 | positive selection | 2545409 | 81121342 | 81121365 | 16 | + | 25494202 | A375 | resistance to PLX-4720 (zeocin) | GCCTGTAGTCCCAGCTACTCAAG | PKD1L2 | ENSG00000166473 | 0.2857588864060996 | [349,998] | [76,442] | 2 | dCas9-VP64 | positive selection | 2563886 | 81168408 | 81168431 | 16 | + | 25494202 | A375 | resistance to PLX-4720 (zeocin) | TGGATGGATGGATGGATGGATGG | PKD1L2 | ENSG00000166473 | -0.745179068402318 | [185,151] | [42,22] | -7 | dCas9-VP64 | positive selection | 2566628 | 81220219 | 81220242 | 16 | + | 27260157 | DLD1 | viability | TCACGGAAGGTGCGTCCGAGTGG | PKD1L2 | ENSG00000166473 | 0.266082873973267 | [] | [] | 4 | hSpCas9 | negative selection | 2574404 | 81215103 | 81215126 | 16 | - | 27260157 | DLD1 | viability | AGGTCCAGGATGCCGTCTACGGG | PKD1L2 | ENSG00000166473 | -0.104119867678736 | [] | [] | 0 | hSpCas9 | negative selection | 2576809 | 81216279 | 81216302 | 16 | + | 27260157 | DLD1 | viability | GTCCGAGGTCACCCACTCAGAGG | PKD1L2 | ENSG00000166473 | 0.190215535345866 | [] | [] | 3 | hSpCas9 | negative selection | 2577547 | 81216360 | 81216383 | 16 | - | 27260157 | DLD1 | viability | CCAATGTGACCTACAGCAACTGG | PKD1L2 | ENSG00000166473 | 0.41430896526308 | [] | [] | 4 | hSpCas9 | negative selection | 2583358 | 81215044 | 81215067 | 16 | - | 27260157 | DLD1 | viability | CGTCCTTCAGATCTGGAGCAGGG | PKD1L2 | ENSG00000166473 | -0.467098797500189 | [] | [] | -4 | hSpCas9 | negative selection | 2586484 | 81215105 | 81215128 | 16 | + | 27260157 | DLD1 | viability | CGTAGACGGCATCCTGGACCTGG | PKD1L2 | ENSG00000166473 | 1.40687777017043 | [] | [] | 9 | hSpCas9 | negative selection | 2609354 | 81220109 | 81220132 | 16 | + | 27260157 | DLD1 | viability | CAATCCACCATTCCCTGTCCTGG | PKD1L2 | ENSG00000166473 | 0.62627290575708 | [] | [] | 8 | hSpCas9 | negative selection | 2609912 | 81215091 | 81215114 | 16 | + | 27260157 | DLD1 | viability | GGGATTCTGGCGCCCGTAGACGG | PKD1L2 | ENSG00000166473 | -0.920947690377978 | [] | [] | -6 | hSpCas9 | negative selection | 2612720 | 81220086 | 81220109 | 16 | - | 27260157 | DLD1 | viability | GACTCACGTGGAACTTGGCACGG | PKD1L2 | ENSG00000166473 | -0.128216265039212 | [] | [] | -1 | hSpCas9 | negative selection | 2621793 | 81216251 | 81216274 | 16 | + | 27260157 | DLD1 | viability | CGCACATGAAGGCGAAGGTCTGG | PKD1L2 | ENSG00000166473 | -0.510370865976033 | [] | [] | -4 | hSpCas9 | negative selection | 2621866 | 81216382 | 81216405 | 16 | + | 27260157 | DLD1 | viability | GAGGTGTCCAACCAAGTCCCCGG | PKD1L2 | ENSG00000166473 | 0.77753646917763 | [] | [] | 8 | hSpCas9 | negative selection | 2640828 | 81216399 | 81216422 | 16 | - | 27260157 | DLD1 | viability | GTGTTGCCCTTCCAGGGCCGGGG | PKD1L2 | ENSG00000166473 | 0.629776365982299 | [] | [] | 8 | hSpCas9 | negative selection | 2641360 | 81216240 | 81216263 | 16 | + | 27260157 | DLD1 | viability | CTCACGGAACTCGCACATGAAGG | PKD1L2 | ENSG00000166473 | 0.202286778777081 | [] | [] | 3 | hSpCas9 | negative selection | 2641889 | 81220073 | 81220096 | 16 | - | 27260157 | DLD1 | viability | CTTGGCACGGAATGGAACCACGG | PKD1L2 | ENSG00000166473 | 0.198722368763627 | [] | [] | 3 | hSpCas9 | negative selection | 2642117 | 81220136 | 81220159 | 16 | + | 27260157 | DLD1 | viability | TGTGCTTCTGCAGAAACCACTGG | PKD1L2 | ENSG00000166473 | 0.768455890861975 | [] | [] | 8 | hSpCas9 | negative selection | 2644662 | 81215067 | 81215090 | 16 | - | 27260157 | DLD1 | viability | ATTTCTGCACCCAGGATGCCGGG | PKD1L2 | ENSG00000166473 | 0.585746021750849 | [] | [] | 8 | hSpCas9 | negative selection | 2647097 | 81215057 | 81215080 | 16 | + | 27260157 | DLD1 | viability | CTGAAGGACGCCCGGCATCCTGG | PKD1L2 | ENSG00000166473 | 0.324768567068162 | [] | [] | 4 | hSpCas9 | negative selection | 2647263 | 81220325 | 81220348 | 16 | + | 27260157 | DLD1 | viability | TAAGCCTCAGAGCAAGCACCAGG | PKD1L2 | ENSG00000166473 | 0.704288055762325 | [] | [] | 8 | hSpCas9 | negative selection | 2648790 | 81220219 | 81220242 | 16 | + | 27260157 | HT1080 | viability | TCACGGAAGGTGCGTCCGAGTGG | PKD1L2 | ENSG00000166473 | 0.734340228106858 | [] | [] | 6 | hSpCas9 | negative selection | 2650534 | 81215103 | 81215126 | 16 | - | 27260157 | HT1080 | viability | AGGTCCAGGATGCCGTCTACGGG | PKD1L2 | ENSG00000166473 | 0.177226791158455 | [] | [] | 1 | hSpCas9 | negative selection | 2652939 | 81216279 | 81216302 | 16 | + | 27260157 | HT1080 | viability | GTCCGAGGTCACCCACTCAGAGG | PKD1L2 | ENSG00000166473 | 0.437163660304337 | [] | [] | 4 | hSpCas9 | negative selection | 2653677 | 81216360 | 81216383 | 16 | - | 27260157 | HT1080 | viability | CCAATGTGACCTACAGCAACTGG | PKD1L2 | ENSG00000166473 | 0.538744989337494 | [] | [] | 5 | hSpCas9 | negative selection | 2659488 | 81215044 | 81215067 | 16 | - | 27260157 | HT1080 | viability | CGTCCTTCAGATCTGGAGCAGGG | PKD1L2 | ENSG00000166473 | -0.270138972964726 | [] | [] | -4 | hSpCas9 | negative selection | 2662614 | 81215105 | 81215128 | 16 | + | 27260157 | HT1080 | viability | CGTAGACGGCATCCTGGACCTGG | PKD1L2 | ENSG00000166473 | 1.10119345384667 | [] | [] | 8 | hSpCas9 | negative selection | 2685484 | 81220109 | 81220132 | 16 | + | 27260157 | HT1080 | viability | CAATCCACCATTCCCTGTCCTGG | PKD1L2 | ENSG00000166473 | 0.00146013682435405 | [] | [] | 0 | hSpCas9 | negative selection | 2686042 | 81215091 | 81215114 | 16 | + | 27260157 | HT1080 | viability | GGGATTCTGGCGCCCGTAGACGG | PKD1L2 | ENSG00000166473 | -0.130681930679969 | [] | [] | 0 | hSpCas9 | negative selection | 2688850 | 81220086 | 81220109 | 16 | - | 27260157 | HT1080 | viability | GACTCACGTGGAACTTGGCACGG | PKD1L2 | ENSG00000166473 | 0.0221995789234047 | [] | [] | 0 | hSpCas9 | negative selection | 2697923 | 81216251 | 81216274 | 16 | + | 27260157 | HT1080 | viability | CGCACATGAAGGCGAAGGTCTGG | PKD1L2 | ENSG00000166473 | 0.3988865358854 | [] | [] | 3 | hSpCas9 | negative selection | 2697996 | 81216382 | 81216405 | 16 | + | 27260157 | HT1080 | viability | GAGGTGTCCAACCAAGTCCCCGG | PKD1L2 | ENSG00000166473 | 1.37099160369604 | [] | [] | 9 | hSpCas9 | negative selection | 2716958 | 81216399 | 81216422 | 16 | - | 27260157 | HT1080 | viability | GTGTTGCCCTTCCAGGGCCGGGG | PKD1L2 | ENSG00000166473 | 0.90241774787668 | [] | [] | 7 | hSpCas9 | negative selection | 2717490 | 81216240 | 81216263 | 16 | + | 27260157 | HT1080 | viability | CTCACGGAACTCGCACATGAAGG | PKD1L2 | ENSG00000166473 | 0.148426860072006 | [] | [] | 1 | hSpCas9 | negative selection | 2718019 | 81220073 | 81220096 | 16 | - | 27260157 | HT1080 | viability | CTTGGCACGGAATGGAACCACGG | PKD1L2 | ENSG00000166473 | 0.0181147311386002 | [] | [] | 0 | hSpCas9 | negative selection | 2718247 | 81220136 | 81220159 | 16 | + | 27260157 | HT1080 | viability | TGTGCTTCTGCAGAAACCACTGG | PKD1L2 | ENSG00000166473 | 1.26533349836886 | [] | [] | 8 | hSpCas9 | negative selection | 2720792 | 81215067 | 81215090 | 16 | - | 27260157 | HT1080 | viability | ATTTCTGCACCCAGGATGCCGGG | PKD1L2 | ENSG00000166473 | 0.969905495988538 | [] | [] | 7 | hSpCas9 | negative selection | 2723227 | 81215057 | 81215080 | 16 | + | 27260157 | HT1080 | viability | CTGAAGGACGCCCGGCATCCTGG | PKD1L2 | ENSG00000166473 | 0.78886953041201 | [] | [] | 7 | hSpCas9 | negative selection | 2723393 | 81220325 | 81220348 | 16 | + | 27260157 | HT1080 | viability | TAAGCCTCAGAGCAAGCACCAGG | PKD1L2 | ENSG00000166473 | 0.29705847349614 | [] | [] | 3 | hSpCas9 | negative selection | 2724920 | 81220219 | 81220242 | 16 | + | 27260157 | MKN45 | viability | TCACGGAAGGTGCGTCCGAGTGG | PKD1L2 | ENSG00000166473 | 1.22668945402851 | [] | [] | 9 | hSpCas9 | negative selection | 2726664 | 81215103 | 81215126 | 16 | - | 27260157 | MKN45 | viability | AGGTCCAGGATGCCGTCTACGGG | PKD1L2 | ENSG00000166473 | 1.07219859502424 | [] | [] | 8 | hSpCas9 | negative selection | 2729069 | 81216279 | 81216302 | 16 | + | 27260157 | MKN45 | viability | GTCCGAGGTCACCCACTCAGAGG | PKD1L2 | ENSG00000166473 | 0.000326310459763372 | [] | [] | 0 | hSpCas9 | negative selection | 2729807 | 81216360 | 81216383 | 16 | - | 27260157 | MKN45 | viability | CCAATGTGACCTACAGCAACTGG | PKD1L2 | ENSG00000166473 | -0.311216830852109 | [] | [] | -1 | hSpCas9 | negative selection | 2735618 | 81215044 | 81215067 | 16 | - | 27260157 | MKN45 | viability | CGTCCTTCAGATCTGGAGCAGGG | PKD1L2 | ENSG00000166473 | 0.88497986552729 | [] | [] | 8 | hSpCas9 | negative selection | 2738744 | 81215105 | 81215128 | 16 | + | 27260157 | MKN45 | viability | CGTAGACGGCATCCTGGACCTGG | PKD1L2 | ENSG00000166473 | 1.13407936385829 | [] | [] | 8 | hSpCas9 | negative selection | 2761614 | 81220109 | 81220132 | 16 | + | 27260157 | MKN45 | viability | CAATCCACCATTCCCTGTCCTGG | PKD1L2 | ENSG00000166473 | 0.506152004360667 | [] | [] | 6 | hSpCas9 | negative selection | 2762172 | 81215091 | 81215114 | 16 | + | 27260157 | MKN45 | viability | GGGATTCTGGCGCCCGTAGACGG | PKD1L2 | ENSG00000166473 | 0.510746223690775 | [] | [] | 6 | hSpCas9 | negative selection | 2764980 | 81220086 | 81220109 | 16 | - | 27260157 | MKN45 | viability | GACTCACGTGGAACTTGGCACGG | PKD1L2 | ENSG00000166473 | 0.649902285403598 | [] | [] | 7 | hSpCas9 | negative selection | 2774053 | 81216251 | 81216274 | 16 | + | 27260157 | MKN45 | viability | CGCACATGAAGGCGAAGGTCTGG | PKD1L2 | ENSG00000166473 | -0.150171909641641 | [] | [] | 0 | hSpCas9 | negative selection | 2774126 | 81216382 | 81216405 | 16 | + | 27260157 | MKN45 | viability | GAGGTGTCCAACCAAGTCCCCGG | PKD1L2 | ENSG00000166473 | 0.636156906697482 | [] | [] | 7 | hSpCas9 | negative selection | 2793088 | 81216399 | 81216422 | 16 | - | 27260157 | MKN45 | viability | GTGTTGCCCTTCCAGGGCCGGGG | PKD1L2 | ENSG00000166473 | -0.691138214582115 | [] | [] | -7 | hSpCas9 | negative selection | 2793620 | 81216240 | 81216263 | 16 | + | 27260157 | MKN45 | viability | CTCACGGAACTCGCACATGAAGG | PKD1L2 | ENSG00000166473 | 0.132047002634483 | [] | [] | 4 | hSpCas9 | negative selection | 2794149 | 81220073 | 81220096 | 16 | - | 27260157 | MKN45 | viability | CTTGGCACGGAATGGAACCACGG | PKD1L2 | ENSG00000166473 | 0.22253327371574 | [] | [] | 5 | hSpCas9 | negative selection | 2794377 | 81220136 | 81220159 | 16 | + | 27260157 | MKN45 | viability | TGTGCTTCTGCAGAAACCACTGG | PKD1L2 | ENSG00000166473 | 2.19108164502418 | [] | [] | 9 | hSpCas9 | negative selection | 2796922 | 81215067 | 81215090 | 16 | - | 27260157 | MKN45 | viability | ATTTCTGCACCCAGGATGCCGGG | PKD1L2 | ENSG00000166473 | 1.23977909610495 | [] | [] | 9 | hSpCas9 | negative selection | 2799357 | 81215057 | 81215080 | 16 | + | 27260157 | MKN45 | viability | CTGAAGGACGCCCGGCATCCTGG | PKD1L2 | ENSG00000166473 | 1.62406810579073 | [] | [] | 9 | hSpCas9 | negative selection | 2799523 | 81220325 | 81220348 | 16 | + | 27260157 | MKN45 | viability | TAAGCCTCAGAGCAAGCACCAGG | PKD1L2 | ENSG00000166473 | 0.720832680487349 | [] | [] | 7 | hSpCas9 | negative selection | 2801050 | 81220219 | 81220242 | 16 | + | 27260157 | RKO | viability | TCACGGAAGGTGCGTCCGAGTGG | PKD1L2 | ENSG00000166473 | -0.109237330803753 | [] | [] | 0 | hSpCas9 | negative selection | 2802794 | 81215103 | 81215126 | 16 | - | 27260157 | RKO | viability | AGGTCCAGGATGCCGTCTACGGG | PKD1L2 | ENSG00000166473 | 1.40302347985681 | [] | [] | 9 | hSpCas9 | negative selection | 2805199 | 81216279 | 81216302 | 16 | + | 27260157 | RKO | viability | GTCCGAGGTCACCCACTCAGAGG | PKD1L2 | ENSG00000166473 | 0.341447312281797 | [] | [] | 1 | hSpCas9 | negative selection | 2805937 | 81216360 | 81216383 | 16 | - | 27260157 | RKO | viability | CCAATGTGACCTACAGCAACTGG | PKD1L2 | ENSG00000166473 | 1.11651300330834 | [] | [] | 9 | hSpCas9 | negative selection | 2811748 | 81215044 | 81215067 | 16 | - | 27260157 | RKO | viability | CGTCCTTCAGATCTGGAGCAGGG | PKD1L2 | ENSG00000166473 | 0.22261576867262 | [] | [] | 1 | hSpCas9 | negative selection | 2814874 | 81215105 | 81215128 | 16 | + | 27260157 | RKO | viability | CGTAGACGGCATCCTGGACCTGG | PKD1L2 | ENSG00000166473 | 1.62488731922638 | [] | [] | 9 | hSpCas9 | negative selection | 2837744 | 81220109 | 81220132 | 16 | + | 27260157 | RKO | viability | CAATCCACCATTCCCTGTCCTGG | PKD1L2 | ENSG00000166473 | 0.286011453423204 | [] | [] | 1 | hSpCas9 | negative selection | 2838302 | 81215091 | 81215114 | 16 | + | 27260157 | RKO | viability | GGGATTCTGGCGCCCGTAGACGG | PKD1L2 | ENSG00000166473 | -0.117660444845174 | [] | [] | 0 | hSpCas9 | negative selection | 2841110 | 81220086 | 81220109 | 16 | - | 27260157 | RKO | viability | GACTCACGTGGAACTTGGCACGG | PKD1L2 | ENSG00000166473 | 0.609256985475087 | [] | [] | 3 | hSpCas9 | negative selection | 2850183 | 81216251 | 81216274 | 16 | + | 27260157 | RKO | viability | CGCACATGAAGGCGAAGGTCTGG | PKD1L2 | ENSG00000166473 | -0.320354615875464 | [] | [] | -6 | hSpCas9 | negative selection | 2850256 | 81216382 | 81216405 | 16 | + | 27260157 | RKO | viability | GAGGTGTCCAACCAAGTCCCCGG | PKD1L2 | ENSG00000166473 | 0.65886190273002 | [] | [] | 3 | hSpCas9 | negative selection | 2869218 | 81216399 | 81216422 | 16 | - | 27260157 | RKO | viability | GTGTTGCCCTTCCAGGGCCGGGG | PKD1L2 | ENSG00000166473 | 0.862937697589878 | [] | [] | 8 | hSpCas9 | negative selection | 2869750 | 81216240 | 81216263 | 16 | + | 27260157 | RKO | viability | CTCACGGAACTCGCACATGAAGG | PKD1L2 | ENSG00000166473 | 0.352762774023628 | [] | [] | 2 | hSpCas9 | negative selection | 2870279 | 81220073 | 81220096 | 16 | - | 27260157 | RKO | viability | CTTGGCACGGAATGGAACCACGG | PKD1L2 | ENSG00000166473 | 0.524995333324581 | [] | [] | 2 | hSpCas9 | negative selection | 2870507 | 81220136 | 81220159 | 16 | + | 27260157 | RKO | viability | TGTGCTTCTGCAGAAACCACTGG | PKD1L2 | ENSG00000166473 | 1.466118471474 | [] | [] | 9 | hSpCas9 | negative selection | 2873052 | 81215067 | 81215090 | 16 | - | 27260157 | RKO | viability | ATTTCTGCACCCAGGATGCCGGG | PKD1L2 | ENSG00000166473 | 0.923951218596567 | [] | [] | 8 | hSpCas9 | negative selection | 2875487 | 81215057 | 81215080 | 16 | + | 27260157 | RKO | viability | CTGAAGGACGCCCGGCATCCTGG | PKD1L2 | ENSG00000166473 | 1.26389717264928 | [] | [] | 9 | hSpCas9 | negative selection | 2875653 | 81220325 | 81220348 | 16 | + | 27260157 | RKO | viability | TAAGCCTCAGAGCAAGCACCAGG | PKD1L2 | ENSG00000166473 | 1.01556811960379 | [] | [] | 9 | hSpCas9 | negative selection | 2877180 | 81220219 | 81220242 | 16 | + | 27260157 | SF268 | viability | TCACGGAAGGTGCGTCCGAGTGG | PKD1L2 | ENSG00000166473 | 1.66510415204354 | [] | [] | 9 | hSpCas9 | negative selection | 2878924 | 81215103 | 81215126 | 16 | - | 27260157 | SF268 | viability | AGGTCCAGGATGCCGTCTACGGG | PKD1L2 | ENSG00000166473 | 1.00897521984586 | [] | [] | 9 | hSpCas9 | negative selection | 2881329 | 81216279 | 81216302 | 16 | + | 27260157 | SF268 | viability | GTCCGAGGTCACCCACTCAGAGG | PKD1L2 | ENSG00000166473 | 0.639366874012324 | [] | [] | 8 | hSpCas9 | negative selection | 2882067 | 81216360 | 81216383 | 16 | - | 27260157 | SF268 | viability | CCAATGTGACCTACAGCAACTGG | PKD1L2 | ENSG00000166473 | 0.664780409449288 | [] | [] | 8 | hSpCas9 | negative selection | 2887878 | 81215044 | 81215067 | 16 | - | 27260157 | SF268 | viability | CGTCCTTCAGATCTGGAGCAGGG | PKD1L2 | ENSG00000166473 | 0.167455029581642 | [] | [] | 0 | hSpCas9 | negative selection | 2891004 | 81215105 | 81215128 | 16 | + | 27260157 | SF268 | viability | CGTAGACGGCATCCTGGACCTGG | PKD1L2 | ENSG00000166473 | 0.755873873890549 | [] | [] | 8 | hSpCas9 | negative selection | 2913874 | 81220109 | 81220132 | 16 | + | 27260157 | SF268 | viability | CAATCCACCATTCCCTGTCCTGG | PKD1L2 | ENSG00000166473 | 0.291504958688379 | [] | [] | 4 | hSpCas9 | negative selection | 2914432 | 81215091 | 81215114 | 16 | + | 27260157 | SF268 | viability | GGGATTCTGGCGCCCGTAGACGG | PKD1L2 | ENSG00000166473 | -0.491418393033151 | [] | [] | -4 | hSpCas9 | negative selection | 2917240 | 81220086 | 81220109 | 16 | - | 27260157 | SF268 | viability | GACTCACGTGGAACTTGGCACGG | PKD1L2 | ENSG00000166473 | 0.520507268970371 | [] | [] | 8 | hSpCas9 | negative selection | 2926313 | 81216251 | 81216274 | 16 | + | 27260157 | SF268 | viability | CGCACATGAAGGCGAAGGTCTGG | PKD1L2 | ENSG00000166473 | 0.392801631397971 | [] | [] | 4 | hSpCas9 | negative selection | 2926386 | 81216382 | 81216405 | 16 | + | 27260157 | SF268 | viability | GAGGTGTCCAACCAAGTCCCCGG | PKD1L2 | ENSG00000166473 | -0.0209645260715094 | [] | [] | 0 | hSpCas9 | negative selection | 2945348 | 81216399 | 81216422 | 16 | - | 27260157 | SF268 | viability | GTGTTGCCCTTCCAGGGCCGGGG | PKD1L2 | ENSG00000166473 | 1.43053671758537 | [] | [] | 9 | hSpCas9 | negative selection | 2945880 | 81216240 | 81216263 | 16 | + | 27260157 | SF268 | viability | CTCACGGAACTCGCACATGAAGG | PKD1L2 | ENSG00000166473 | 0.355930657238868 | [] | [] | 4 | hSpCas9 | negative selection | 2946409 | 81220073 | 81220096 | 16 | - | 27260157 | SF268 | viability | CTTGGCACGGAATGGAACCACGG | PKD1L2 | ENSG00000166473 | 0.189571520743712 | [] | [] | 0 | hSpCas9 | negative selection | 2946637 | 81220136 | 81220159 | 16 | + | 27260157 | SF268 | viability | TGTGCTTCTGCAGAAACCACTGG | PKD1L2 | ENSG00000166473 | -0.815141415375379 | [] | [] | -6 | hSpCas9 | negative selection | 2949182 | 81215067 | 81215090 | 16 | - | 27260157 | SF268 | viability | ATTTCTGCACCCAGGATGCCGGG | PKD1L2 | ENSG00000166473 | 0.698837447285868 | [] | [] | 8 | hSpCas9 | negative selection | 2951617 | 81215057 | 81215080 | 16 | + | 27260157 | SF268 | viability | CTGAAGGACGCCCGGCATCCTGG | PKD1L2 | ENSG00000166473 | 1.18997933416758 | [] | [] | 9 | hSpCas9 | negative selection | 2951783 | 81220325 | 81220348 | 16 | + | 27260157 | SF268 | viability | TAAGCCTCAGAGCAAGCACCAGG | PKD1L2 | ENSG00000166473 | 0.392942363553843 | [] | [] | 4 | hSpCas9 | negative selection | 2953310 | 81216240 | 81216263 | | + | 24336571 | A375 | resistance to PLX after 7 days | CTCACGGAACTCGCACATGAAGG | PKD1L2 | ENSG00000166473 | -0.5871462496478017 | [8,7] | [4,5] | -9 | hSpCas9 | positive selection | 3135816 | 81216382 | 81216405 | | + | 24336571 | A375 | resistance to PLX after 7 days | GAGGTGTCCAACCAAGTCCCCGG | PKD1L2 | ENSG00000166473 | -0.06910593983724111 | [17,17] | [16,16] | -2 | hSpCas9 | positive selection | 3135817 | 81215099 | 81215122 | | + | 24336571 | A375 | resistance to PLX after 7 days | GGCGCCCGTAGACGGCATCCTGG | PKD1L2 | ENSG00000166473 | -0.23358541385915133 | [7,5] | [6,4] | -7 | hSpCas9 | positive selection | 3135818 | 81215051 | 81215074 | | - | 24336571 | A375 | resistance to PLX after 7 days | TGCCGGGCGTCCTTCAGATCTGG | PKD1L2 | ENSG00000166473 | -0.5005671667235232 | [6,6] | [4,3] | -9 | hSpCas9 | positive selection | 3135819 | 81216240 | 81216263 | | + | 24336571 | A375 | resistance to PLX after 14 days | CTCACGGAACTCGCACATGAAGG | PKD1L2 | ENSG00000166473 | -0.5409088590551563 | [4,6] | [1,1] | -6 | hSpCas9 | positive selection | 3193609 | 81216382 | 81216405 | | + | 24336571 | A375 | resistance to PLX after 14 days | GAGGTGTCCAACCAAGTCCCCGG | PKD1L2 | ENSG00000166473 | 0.2591005474157864 | [16,16] | [8,9] | 2 | hSpCas9 | positive selection | 3193610 | 81215099 | 81215122 | | + | 24336571 | A375 | resistance to PLX after 14 days | GGCGCCCGTAGACGGCATCCTGG | PKD1L2 | ENSG00000166473 | -0.33491774727198653 | [10,4] | [2,2] | -4 | hSpCas9 | positive selection | 3193611 | 81215051 | 81215074 | | - | 24336571 | A375 | resistance to PLX after 14 days | TGCCGGGCGTCCTTCAGATCTGG | PKD1L2 | ENSG00000166473 | 0.6700636145650013 | [5,3] | [2,4] | 6 | hSpCas9 | positive selection | 3193612 | 81216240 | 81216263 | | + | 24336571 | A375 | viability after 7 days | CTCACGGAACTCGCACATGAAGG | PKD1L2 | ENSG00000166473 | 0.1575422844539638 | [7] | [8,7] | 2 | hSpCas9 | negative selection | 3251402 | 81216382 | 81216405 | | + | 24336571 | A375 | viability after 7 days | GAGGTGTCCAACCAAGTCCCCGG | PKD1L2 | ENSG00000166473 | 0.3736287521825706 | [14] | [17,17] | 5 | hSpCas9 | negative selection | 3251403 | 81215099 | 81215122 | | + | 24336571 | A375 | viability after 7 days | GGCGCCCGTAGACGGCATCCTGG | PKD1L2 | ENSG00000166473 | -0.18326798196851168 | [8] | [7,5] | -3 | hSpCas9 | negative selection | 3251404 | 81215051 | 81215074 | | - | 24336571 | A375 | viability after 7 days | TGCCGGGCGTCCTTCAGATCTGG | PKD1L2 | ENSG00000166473 | 0.27318492066144895 | [5] | [6,6] | 4 | hSpCas9 | negative selection | 3251405 | 81216240 | 81216263 | | + | 24336571 | A375 | viability after 14 days | CTCACGGAACTCGCACATGAAGG | PKD1L2 | ENSG00000166473 | -0.27975860638487027 | [7] | [4,6] | -3 | hSpCas9 | negative selection | 3309195 | 81216382 | 81216405 | | + | 24336571 | A375 | viability after 14 days | GAGGTGTCCAACCAAGTCCCCGG | PKD1L2 | ENSG00000166473 | 0.3188014400131879 | [14] | [16,16] | 4 | hSpCas9 | negative selection | 3309196 | 81215099 | 81215122 | | + | 24336571 | A375 | viability after 14 days | GGCGCCCGTAGACGGCATCCTGG | PKD1L2 | ENSG00000166473 | -0.04227645734979424 | [8] | [10,4] | 0 | hSpCas9 | negative selection | 3309197 | 81215051 | 81215074 | | - | 24336571 | A375 | viability after 14 days | TGCCGGGCGTCCTTCAGATCTGG | PKD1L2 | ENSG00000166473 | -0.04912073760593727 | [5] | [5,3] | 0 | hSpCas9 | negative selection | 3309198 | 81216240 | 81216263 | 16 | + | 26780180 | A375 | resistance to vemurafenib (GeCKOv1 lentiCRISPRv1) | CTCACGGAACTCGCACATGAAGG | PKD1L2 | ENSG00000166473 | -1.0322655054304304 | [3] | [0,0] | -9 | hSpCas9 | positive selection | 4160793 | 81216382 | 81216405 | 16 | + | 26780180 | A375 | resistance to vemurafenib (GeCKOv1 lentiCRISPRv1) | GAGGTGTCCAACCAAGTCCCCGG | PKD1L2 | ENSG00000166473 | 0.10594086628378269 | [4] | [2,3] | 2 | hSpCas9 | positive selection | 4160794 | 81215099 | 81215122 | 16 | + | 26780180 | A375 | resistance to vemurafenib (GeCKOv1 lentiCRISPRv1) | GGCGCCCGTAGACGGCATCCTGG | PKD1L2 | ENSG00000166473 | -0.20756915612714294 | [2] | [1,1] | -5 | hSpCas9 | positive selection | 4160795 | 81215051 | 81215074 | 16 | - | 26780180 | A375 | resistance to vemurafenib (GeCKOv1 lentiCRISPRv1) | TGCCGGGCGTCCTTCAGATCTGG | PKD1L2 | ENSG00000166473 | -0.39499996138013255 | [2] | [0,1] | -7 | hSpCas9 | positive selection | 4160797 | 81216240 | 81216263 | 16 | + | 26780180 | A375 | resistance to vemurafenib (GeCKOv1 lentiGuide) | CTCACGGAACTCGCACATGAAGG | PKD1L2 | ENSG00000166473 | 0.1654001528048599 | [3] | [1,4,0,0] | 1 | hSpCas9 | positive selection | 4224815 | 81216382 | 81216405 | 16 | + | 26780180 | A375 | resistance to vemurafenib (GeCKOv1 lentiGuide) | GAGGTGTCCAACCAAGTCCCCGG | PKD1L2 | ENSG00000166473 | -0.03704785216062512 | [4] | [2,1,3,0] | 0 | hSpCas9 | positive selection | 4224816 | 81215099 | 81215122 | 16 | + | 26780180 | A375 | resistance to vemurafenib (GeCKOv1 lentiGuide) | GGCGCCCGTAGACGGCATCCTGG | PKD1L2 | ENSG00000166473 | 1.2557654228909936 | [2] | [0,0,0,4] | 9 | hSpCas9 | positive selection | 4224817 | 81215051 | 81215074 | 16 | - | 26780180 | A375 | resistance to vemurafenib (GeCKOv1 lentiGuide) | TGCCGGGCGTCCTTCAGATCTGG | PKD1L2 | ENSG00000166473 | 0.612390218377576 | [1] | [3,2,0,0] | 4 | hSpCas9 | positive selection | 4224819 | 81220296 | 81220319 | 16 | + | 27661255 | K562 | viability | GCCTTCCTCTGGCTTAACAGTGG | PKD1L2 | ENSG00000166473 | 0.552740843410862 | [85,138] | [127,132] | 9 | dCas9-KRAB | negative selection | 5502121 | 81220065 | 81220088 | 16 | - | 27661255 | K562 | viability | GGAATGGAACCACGGAGGGTAGG | PKD1L2 | ENSG00000166473 | -0.01331473459973953 | [928,854] | [834,597] | 0 | dCas9-KRAB | negative selection | 5502122 | 81220301 | 81220324 | 16 | - | 27661255 | K562 | viability | GGCCACCACTGTTAAGCCAGAGG | PKD1L2 | ENSG00000166473 | 0.1708460995477934 | [290,258] | [263,233] | 6 | dCas9-KRAB | negative selection | 5502123 | 81202613 | 81202636 | 16 | - | 27869803 | HPAFII | viability after 27 days | GGTGACCGTGCGAGACAAGATGG | PKD1L2 | ENSG00000166473 | 1.1134118467273766 | [81] | [107,80,NaN] | 8 | hSpCas9 | negative selection | 9558564 | 81207571 | 81207594 | 16 | - | 27869803 | HPAFII | viability after 27 days | ATGTCACCATCTCCCTGACGTGG | PKD1L2 | ENSG00000166473 | -0.5843185841557293 | [433] | [263,58,NaN] | -4 | hSpCas9 | negative selection | 9558565 | 81208554 | 81208577 | 16 | + | 27869803 | HPAFII | viability after 27 days | AGGTCTCATCTGCTGCCACCTGG | PKD1L2 | ENSG00000166473 | 0.4143775792974256 | [40] | [61,0,NaN] | 3 | hSpCas9 | negative selection | 9558566 | 81215069 | 81215092 | 16 | + | 27869803 | HPAFII | viability after 27 days | CGGCATCCTGGGTGCAGAAATGG | PKD1L2 | ENSG00000166473 | 0.6364897634109343 | [809] | [793,551,NaN] | 5 | hSpCas9 | negative selection | 9558567 | 81216360 | 81216383 | 16 | - | 27869803 | HPAFII | viability after 27 days | CCAATGTGACCTACAGCAACTGG | PKD1L2 | ENSG00000166473 | 0.009243191455576394 | [856] | [441,462,NaN] | 0 | hSpCas9 | negative selection | 9558568 | 81220069 | 81220092 | 16 | - | 27869803 | HPAFII | viability after 27 days | GCACGGAATGGAACCACGGAGGG | PKD1L2 | ENSG00000166473 | 0.37050621460566346 | [339] | [301,171,NaN] | 3 | hSpCas9 | negative selection | 9558569 | 81202613 | 81202636 | 16 | - | 27869803 | HPAFII | viability after 15 days | GGTGACCGTGCGAGACAAGATGG | PKD1L2 | ENSG00000166473 | 0.7363936861876315 | [81] | [197,114,NaN] | 7 | hSpCas9 | negative selection | 9641013 | 81207571 | 81207594 | 16 | - | 27869803 | HPAFII | viability after 15 days | ATGTCACCATCTCCCTGACGTGG | PKD1L2 | ENSG00000166473 | 0.003678646245075079 | [433] | [889,204,NaN] | 0 | hSpCas9 | negative selection | 9641014 | 81208554 | 81208577 | 16 | + | 27869803 | HPAFII | viability after 15 days | AGGTCTCATCTGCTGCCACCTGG | PKD1L2 | ENSG00000166473 | 0.7442022111087079 | [40] | [169,13,NaN] | 8 | hSpCas9 | negative selection | 9641015 | 81215069 | 81215092 | 16 | + | 27869803 | HPAFII | viability after 15 days | CGGCATCCTGGGTGCAGAAATGG | PKD1L2 | ENSG00000166473 | 0.8088428172407613 | [809] | [2066,1187,NaN] | 8 | hSpCas9 | negative selection | 9641016 | 81216360 | 81216383 | 16 | - | 27869803 | HPAFII | viability after 15 days | CCAATGTGACCTACAGCAACTGG | PKD1L2 | ENSG00000166473 | 0.02196401287467431 | [856] | [1002,892,NaN] | 0 | hSpCas9 | negative selection | 9641017 | 81220069 | 81220092 | 16 | - | 27869803 | HPAFII | viability after 15 days | GCACGGAATGGAACCACGGAGGG | PKD1L2 | ENSG00000166473 | 0.06444389591516486 | [339] | [563,268,NaN] | 0 | hSpCas9 | negative selection | 9641018 | 81202613 | 81202636 | 16 | - | 27869803 | ASPC1 | viability after 36 days | GGTGACCGTGCGAGACAAGATGG | PKD1L2 | ENSG00000166473 | 0.1691291021076835 | [174] | [53,0,131] | 1 | hSpCas9 | negative selection | 9723462 | 81207571 | 81207594 | 16 | - | 27869803 | ASPC1 | viability after 36 days | ATGTCACCATCTCCCTGACGTGG | PKD1L2 | ENSG00000166473 | 0.15264153728778995 | [978] | [601,384,215] | 1 | hSpCas9 | negative selection | 9723463 | 81208554 | 81208577 | 16 | + | 27869803 | ASPC1 | viability after 36 days | AGGTCTCATCTGCTGCCACCTGG | PKD1L2 | ENSG00000166473 | -0.09489428356596097 | [132] | [0,12,96] | -1 | hSpCas9 | negative selection | 9723464 | 81215069 | 81215092 | 16 | + | 27869803 | ASPC1 | viability after 36 days | CGGCATCCTGGGTGCAGAAATGG | PKD1L2 | ENSG00000166473 | 0.0648814436019256 | [2522] | [904,1099,780] | 0 | hSpCas9 | negative selection | 9723465 | 81216360 | 81216383 | 16 | - | 27869803 | ASPC1 | viability after 36 days | CCAATGTGACCTACAGCAACTGG | PKD1L2 | ENSG00000166473 | 0.000494212612985212 | [2016] | [500,733,815] | 0 | hSpCas9 | negative selection | 9723466 | 81220069 | 81220092 | 16 | - | 27869803 | ASPC1 | viability after 36 days | GCACGGAATGGAACCACGGAGGG | PKD1L2 | ENSG00000166473 | -0.7001659863604599 | [866] | [259,181,135] | -6 | hSpCas9 | negative selection | 9723467 | 81202613 | 81202636 | 16 | - | 27869803 | PATU8988S | viability after 35 days | GGTGACCGTGCGAGACAAGATGG | PKD1L2 | ENSG00000166473 | 0.7039466173730855 | [178] | [88,145,NaN] | 7 | hSpCas9 | negative selection | 9805911 | 81207571 | 81207594 | 16 | - | 27869803 | PATU8988S | viability after 35 days | ATGTCACCATCTCCCTGACGTGG | PKD1L2 | ENSG00000166473 | 0.005496401221006364 | [843] | [436,244,NaN] | 0 | hSpCas9 | negative selection | 9805912 | 81208554 | 81208577 | 16 | + | 27869803 | PATU8988S | viability after 35 days | AGGTCTCATCTGCTGCCACCTGG | PKD1L2 | ENSG00000166473 | -0.034155800685153004 | [84] | [3,62,NaN] | 0 | hSpCas9 | negative selection | 9805913 | 81215069 | 81215092 | 16 | + | 27869803 | PATU8988S | viability after 35 days | CGGCATCCTGGGTGCAGAAATGG | PKD1L2 | ENSG00000166473 | 0.6994820983704328 | [2217] | [1515,1384,NaN] | 7 | hSpCas9 | negative selection | 9805914 | 81216360 | 81216383 | 16 | - | 27869803 | PATU8988S | viability after 35 days | CCAATGTGACCTACAGCAACTGG | PKD1L2 | ENSG00000166473 | 0.06125646236294924 | [1616] | [676,681,NaN] | 0 | hSpCas9 | negative selection | 9805915 | 81220069 | 81220092 | 16 | - | 27869803 | PATU8988S | viability after 35 days | GCACGGAATGGAACCACGGAGGG | PKD1L2 | ENSG00000166473 | 0.981747373487622 | [709] | [658,469,NaN] | 8 | hSpCas9 | negative selection | 9805916 | 81202613 | 81202636 | 16 | - | 27869803 | PATU8988S | viability after 31 days | GGTGACCGTGCGAGACAAGATGG | PKD1L2 | ENSG00000166473 | 1.0292682131385278 | [178] | [124,171,NaN] | 9 | hSpCas9 | negative selection | 9888360 | 81207571 | 81207594 | 16 | - | 27869803 | PATU8988S | viability after 31 days | ATGTCACCATCTCCCTGACGTGG | PKD1L2 | ENSG00000166473 | -0.4843648913861427 | [843] | [251,225,NaN] | -5 | hSpCas9 | negative selection | 9888361 | 81208554 | 81208577 | 16 | + | 27869803 | PATU8988S | viability after 31 days | AGGTCTCATCTGCTGCCACCTGG | PKD1L2 | ENSG00000166473 | 0.5983266210624811 | [84] | [16,94,NaN] | 7 | hSpCas9 | negative selection | 9888362 | 81215069 | 81215092 | 16 | + | 27869803 | PATU8988S | viability after 31 days | CGGCATCCTGGGTGCAGAAATGG | PKD1L2 | ENSG00000166473 | 0.48902196932723463 | [2217] | [1180,1317,NaN] | 6 | hSpCas9 | negative selection | 9888363 | 81216360 | 81216383 | 16 | - | 27869803 | PATU8988S | viability after 31 days | CCAATGTGACCTACAGCAACTGG | PKD1L2 | ENSG00000166473 | -0.16373445088282756 | [1616] | [535,625,NaN] | -2 | hSpCas9 | negative selection | 9888364 | 81220069 | 81220092 | 16 | - | 27869803 | PATU8988S | viability after 31 days | GCACGGAATGGAACCACGGAGGG | PKD1L2 | ENSG00000166473 | 0.8561331457339733 | [709] | [493,535,NaN] | 8 | hSpCas9 | negative selection | 9888365 | 81202613 | 81202636 | 16 | - | 27869803 | HPAFII | viability after 35 days | GGTGACCGTGCGAGACAAGATGG | PKD1L2 | ENSG00000166473 | 0.7957281829495785 | [81] | [80,61,NaN] | 5 | hSpCas9 | negative selection | 9970809 | 81207571 | 81207594 | 16 | - | 27869803 | HPAFII | viability after 35 days | ATGTCACCATCTCCCTGACGTGG | PKD1L2 | ENSG00000166473 | 0.21166700661840032 | [433] | [411,76,NaN] | 1 | hSpCas9 | negative selection | 9970810 | 81208554 | 81208577 | 16 | + | 27869803 | HPAFII | viability after 35 days | AGGTCTCATCTGCTGCCACCTGG | PKD1L2 | ENSG00000166473 | 1.2518757755954155 | [40] | [87,5,NaN] | 8 | hSpCas9 | negative selection | 9970811 | 81215069 | 81215092 | 16 | + | 27869803 | HPAFII | viability after 35 days | CGGCATCCTGGGTGCAGAAATGG | PKD1L2 | ENSG00000166473 | 0.6559567751457924 | [809] | [639,652,NaN] | 4 | hSpCas9 | negative selection | 9970812 | 81216360 | 81216383 | 16 | - | 27869803 | HPAFII | viability after 35 days | CCAATGTGACCTACAGCAACTGG | PKD1L2 | ENSG00000166473 | 0.12432004964676113 | [856] | [502,438,NaN] | 0 | hSpCas9 | negative selection | 9970813 | 81220069 | 81220092 | 16 | - | 27869803 | HPAFII | viability after 35 days | GCACGGAATGGAACCACGGAGGG | PKD1L2 | ENSG00000166473 | 0.29779102526493606 | [339] | [204,218,NaN] | 2 | hSpCas9 | negative selection | 9970814 | 81202613 | 81202636 | 16 | - | 27869803 | HPAFII | viability after 31 days | GGTGACCGTGCGAGACAAGATGG | PKD1L2 | ENSG00000166473 | 1.0748818928231842 | [81] | [117,73,NaN] | 7 | hSpCas9 | negative selection | 10053258 | 81207571 | 81207594 | 16 | - | 27869803 | HPAFII | viability after 31 days | ATGTCACCATCTCCCTGACGTGG | PKD1L2 | ENSG00000166473 | -0.5180012850675516 | [433] | [294,33,NaN] | -3 | hSpCas9 | negative selection | 10053259 | 81208554 | 81208577 | 16 | + | 27869803 | HPAFII | viability after 31 days | AGGTCTCATCTGCTGCCACCTGG | PKD1L2 | ENSG00000166473 | 0.5041989053206559 | [40] | [57,4,NaN] | 3 | hSpCas9 | negative selection | 10053260 | 81215069 | 81215092 | 16 | + | 27869803 | HPAFII | viability after 31 days | CGGCATCCTGGGTGCAGAAATGG | PKD1L2 | ENSG00000166473 | 0.8303273903464292 | [809] | [624,1007,NaN] | 6 | hSpCas9 | negative selection | 10053261 | 81216360 | 81216383 | 16 | - | 27869803 | HPAFII | viability after 31 days | CCAATGTGACCTACAGCAACTGG | PKD1L2 | ENSG00000166473 | 0.09666611201416675 | [856] | [598,421,NaN] | 0 | hSpCas9 | negative selection | 10053262 | 81220069 | 81220092 | 16 | - | 27869803 | HPAFII | viability after 31 days | GCACGGAATGGAACCACGGAGGG | PKD1L2 | ENSG00000166473 | 0.47821632702387484 | [339] | [294,233,NaN] | 3 | hSpCas9 | negative selection | 10053263 | 81137476 | 81137499 | 16 | - | 28162770 | P31FUJ | viability | GAAGAGAGTGGACGATGAGGAGG | PKD1L2 | ENSG00000166473 | -0.1450436986398178 | [1147] | [1219] | -1 | hSpCas9 | negative selection | 10211809 | 81163599 | 81163622 | 16 | - | 28162770 | P31FUJ | viability | GAATCTGTCGGAGAATATCGAGG | PKD1L2 | ENSG00000166473 | 0.23466673328833698 | [1789] | [2474] | 2 | hSpCas9 | negative selection | 10211810 | 81117372 | 81117395 | 16 | - | 28162770 | P31FUJ | viability | GCGCTGCCGGAACCACAGGGAGG | PKD1L2 | ENSG00000166473 | 0.3605432079861868 | [571] | [862] | 4 | hSpCas9 | negative selection | 10211811 | 81168017 | 81168040 | 16 | + | 28162770 | P31FUJ | viability | GGCGCCTCTGGTCCTCAGGGCGG | PKD1L2 | ENSG00000166473 | -2.3796435927436494 | [1084] | [244] | -8 | hSpCas9 | negative selection | 10211812 | 81167933 | 81167956 | 16 | - | 28162770 | P31FUJ | viability | CAGACCAGAAGAGCCTGCGGAGG | PKD1L2 | ENSG00000166473 | 0.38588091415077863 | [591] | [908] | 4 | hSpCas9 | negative selection | 10211813 | 81137476 | 81137499 | 16 | - | 28162770 | TF1 | viability | GAAGAGAGTGGACGATGAGGAGG | PKD1L2 | ENSG00000166473 | NaN | [NaN] | [86] | 1 | hSpCas9 | negative selection | 10381175 | 81163599 | 81163622 | 16 | - | 28162770 | TF1 | viability | GAATCTGTCGGAGAATATCGAGG | PKD1L2 | ENSG00000166473 | NaN | [NaN] | [246] | 1 | hSpCas9 | negative selection | 10381176 | 81117372 | 81117395 | 16 | - | 28162770 | TF1 | viability | GCGCTGCCGGAACCACAGGGAGG | PKD1L2 | ENSG00000166473 | NaN | [NaN] | [75] | 1 | hSpCas9 | negative selection | 10381177 | 81168017 | 81168040 | 16 | + | 28162770 | TF1 | viability | GGCGCCTCTGGTCCTCAGGGCGG | PKD1L2 | ENSG00000166473 | NaN | [NaN] | [7] | 1 | hSpCas9 | negative selection | 10381178 | 81167933 | 81167956 | 16 | - | 28162770 | TF1 | viability | CAGACCAGAAGAGCCTGCGGAGG | PKD1L2 | ENSG00000166473 | NaN | [NaN] | [94] | 1 | hSpCas9 | negative selection | 10381179 | 81137476 | 81137499 | 16 | - | 28162770 | SKM1 | viability | GAAGAGAGTGGACGATGAGGAGG | PKD1L2 | ENSG00000166473 | -0.49038020693079915 | [88] | [111] | -4 | hSpCas9 | negative selection | 10550541 | 81163599 | 81163622 | 16 | - | 28162770 | SKM1 | viability | GAATCTGTCGGAGAATATCGAGG | PKD1L2 | ENSG00000166473 | 0.05531578220316591 | [91] | [168] | 0 | hSpCas9 | negative selection | 10550542 | 81117372 | 81117395 | 16 | - | 28162770 | SKM1 | viability | GCGCTGCCGGAACCACAGGGAGG | PKD1L2 | ENSG00000166473 | 0.19846240453771008 | [34] | [70] | 2 | hSpCas9 | negative selection | 10550543 | 81168017 | 81168040 | 16 | + | 28162770 | SKM1 | viability | GGCGCCTCTGGTCCTCAGGGCGG | PKD1L2 | ENSG00000166473 | -2.0564669516590284 | [79] | [33] | -8 | hSpCas9 | negative selection | 10550544 | 81167933 | 81167956 | 16 | - | 28162770 | SKM1 | viability | CAGACCAGAAGAGCCTGCGGAGG | PKD1L2 | ENSG00000166473 | 0.05935380547937541 | [37] | [69] | 0 | hSpCas9 | negative selection | 10550545 | 81137476 | 81137499 | 16 | - | 28162770 | SKM1 | viability | GAAGAGAGTGGACGATGAGGAGG | PKD1L2 | ENSG00000166473 | -0.49038020693079915 | [88] | [111] | -4 | hSpCas9 | negative selection | 10719907 | 81163599 | 81163622 | 16 | - | 28162770 | SKM1 | viability | GAATCTGTCGGAGAATATCGAGG | PKD1L2 | ENSG00000166473 | 0.05531578220316591 | [91] | [168] | 0 | hSpCas9 | negative selection | 10719908 | 81117372 | 81117395 | 16 | - | 28162770 | SKM1 | viability | GCGCTGCCGGAACCACAGGGAGG | PKD1L2 | ENSG00000166473 | 0.19846240453771008 | [34] | [70] | 2 | hSpCas9 | negative selection | 10719909 | 81168017 | 81168040 | 16 | + | 28162770 | SKM1 | viability | GGCGCCTCTGGTCCTCAGGGCGG | PKD1L2 | ENSG00000166473 | -2.0564669516590284 | [79] | [33] | -8 | hSpCas9 | negative selection | 10719910 | 81167933 | 81167956 | 16 | - | 28162770 | SKM1 | viability | CAGACCAGAAGAGCCTGCGGAGG | PKD1L2 | ENSG00000166473 | 0.05935380547937541 | [37] | [69] | 0 | hSpCas9 | negative selection | 10719911 | 81137476 | 81137499 | 16 | - | 28162770 | PL21 | viability | GAAGAGAGTGGACGATGAGGAGG | PKD1L2 | ENSG00000166473 | 0.19517336159597076 | [290] | [144] | 1 | hSpCas9 | negative selection | 10889273 | 81163599 | 81163622 | 16 | - | 28162770 | PL21 | viability | GAATCTGTCGGAGAATATCGAGG | PKD1L2 | ENSG00000166473 | -0.005064874096359917 | [444] | [192] | 0 | hSpCas9 | negative selection | 10889274 | 81117372 | 81117395 | 16 | - | 28162770 | PL21 | viability | GCGCTGCCGGAACCACAGGGAGG | PKD1L2 | ENSG00000166473 | -0.2225514573329589 | [125] | [46] | -2 | hSpCas9 | negative selection | 10889275 | 81168017 | 81168040 | 16 | + | 28162770 | PL21 | viability | GGCGCCTCTGGTCCTCAGGGCGG | PKD1L2 | ENSG00000166473 | -0.9551386109885909 | [293] | [65] | -6 | hSpCas9 | negative selection | 10889276 | 81167933 | 81167956 | 16 | - | 28162770 | PL21 | viability | CAGACCAGAAGAGCCTGCGGAGG | PKD1L2 | ENSG00000166473 | -0.31175942404211254 | [153] | [53] | -2 | hSpCas9 | negative selection | 10889277 | 81137476 | 81137499 | 16 | - | 28162770 | P31FUJ | viability | GAAGAGAGTGGACGATGAGGAGG | PKD1L2 | ENSG00000166473 | -0.1450436986398178 | [1147] | [1219] | -1 | hSpCas9 | negative selection | 11058639 | 81163599 | 81163622 | 16 | - | 28162770 | P31FUJ | viability | GAATCTGTCGGAGAATATCGAGG | PKD1L2 | ENSG00000166473 | 0.23466673328833698 | [1789] | [2474] | 2 | hSpCas9 | negative selection | 11058640 | 81117372 | 81117395 | 16 | - | 28162770 | P31FUJ | viability | GCGCTGCCGGAACCACAGGGAGG | PKD1L2 | ENSG00000166473 | 0.3605432079861868 | [571] | [862] | 4 | hSpCas9 | negative selection | 11058641 | 81168017 | 81168040 | 16 | + | 28162770 | P31FUJ | viability | GGCGCCTCTGGTCCTCAGGGCGG | PKD1L2 | ENSG00000166473 | -2.3796435927436494 | [1084] | [244] | -8 | hSpCas9 | negative selection | 11058642 | 81167933 | 81167956 | 16 | - | 28162770 | P31FUJ | viability | CAGACCAGAAGAGCCTGCGGAGG | PKD1L2 | ENSG00000166473 | 0.38588091415077863 | [591] | [908] | 4 | hSpCas9 | negative selection | 11058643 | 81137476 | 81137499 | 16 | - | 28162770 | OCIAML5 | viability | GAAGAGAGTGGACGATGAGGAGG | PKD1L2 | ENSG00000166473 | -0.7893308155160343 | [179] | [187] | -5 | hSpCas9 | negative selection | 11228005 | 81163599 | 81163622 | 16 | - | 28162770 | OCIAML5 | viability | GAATCTGTCGGAGAATATCGAGG | PKD1L2 | ENSG00000166473 | 0.6678009016352742 | [271] | [779] | 6 | hSpCas9 | negative selection | 11228006 | 81117372 | 81117395 | 16 | - | 28162770 | OCIAML5 | viability | GCGCTGCCGGAACCACAGGGAGG | PKD1L2 | ENSG00000166473 | 0.2694954090169162 | [90] | [197] | 2 | hSpCas9 | negative selection | 11228007 | 81168017 | 81168040 | 16 | + | 28162770 | OCIAML5 | viability | GGCGCCTCTGGTCCTCAGGGCGG | PKD1L2 | ENSG00000166473 | -2.3157227753630196 | [170] | [61] | -8 | hSpCas9 | negative selection | 11228008 | 81167933 | 81167956 | 16 | - | 28162770 | OCIAML5 | viability | CAGACCAGAAGAGCCTGCGGAGG | PKD1L2 | ENSG00000166473 | 1.285436952885938 | [49] | [219] | 9 | hSpCas9 | negative selection | 11228009 | 81137476 | 81137499 | 16 | - | 28162770 | EOL1 | viability | GAAGAGAGTGGACGATGAGGAGG | PKD1L2 | ENSG00000166473 | 0.348518395619386 | [482] | [323] | 3 | hSpCas9 | negative selection | 11397371 | 81163599 | 81163622 | 16 | - | 28162770 | EOL1 | viability | GAATCTGTCGGAGAATATCGAGG | PKD1L2 | ENSG00000166473 | 0.13051199191042862 | [592] | [341] | 1 | hSpCas9 | negative selection | 11397372 | 81117372 | 81117395 | 16 | - | 28162770 | EOL1 | viability | GCGCTGCCGGAACCACAGGGAGG | PKD1L2 | ENSG00000166473 | -0.44860564667200103 | [214] | [82] | -3 | hSpCas9 | negative selection | 11397373 | 81168017 | 81168040 | 16 | + | 28162770 | EOL1 | viability | GGCGCCTCTGGTCCTCAGGGCGG | PKD1L2 | ENSG00000166473 | -2.067590110656495 | [365] | [45] | -8 | hSpCas9 | negative selection | 11397374 | 81167933 | 81167956 | 16 | - | 28162770 | EOL1 | viability | CAGACCAGAAGAGCCTGCGGAGG | PKD1L2 | ENSG00000166473 | 0.514785214332365 | [181] | [136] | 4 | hSpCas9 | negative selection | 11397375 | 81137476 | 81137499 | 16 | - | 28162770 | MOLM13 | viability | GAAGAGAGTGGACGATGAGGAGG | PKD1L2 | ENSG00000166473 | 0.4432973933621865 | [354] | [348] | 3 | hSpCas9 | negative selection | 11566737 | 81163599 | 81163622 | 16 | - | 28162770 | MOLM13 | viability | GAATCTGTCGGAGAATATCGAGG | PKD1L2 | ENSG00000166473 | 0.47260407541663074 | [610] | [612] | 3 | hSpCas9 | negative selection | 11566738 | 81117372 | 81117395 | 16 | - | 28162770 | MOLM13 | viability | GCGCTGCCGGAACCACAGGGAGG | PKD1L2 | ENSG00000166473 | 0.7996365374623868 | [204] | [257] | 6 | hSpCas9 | negative selection | 11566739 | 81168017 | 81168040 | 16 | + | 28162770 | MOLM13 | viability | GGCGCCTCTGGTCCTCAGGGCGG | PKD1L2 | ENSG00000166473 | -4.281048854287703 | [241] | [8] | -9 | hSpCas9 | negative selection | 11566740 | 81167933 | 81167956 | 16 | - | 28162770 | MOLM13 | viability | CAGACCAGAAGAGCCTGCGGAGG | PKD1L2 | ENSG00000166473 | 0.7166331298279791 | [185] | [220] | 5 | hSpCas9 | negative selection | 11566741 | 81137476 | 81137499 | 16 | - | 28162770 | HEL | viability | GAAGAGAGTGGACGATGAGGAGG | PKD1L2 | ENSG00000166473 | 0.036081260179881836 | [334] | [219] | 0 | hSpCas9 | negative selection | 11736103 | 81163599 | 81163622 | 16 | - | 28162770 | HEL | viability | GAATCTGTCGGAGAATATCGAGG | PKD1L2 | ENSG00000166473 | 0.370867062907386 | [523] | [433] | 3 | hSpCas9 | negative selection | 11736104 | 81117372 | 81117395 | 16 | - | 28162770 | HEL | viability | GCGCTGCCGGAACCACAGGGAGG | PKD1L2 | ENSG00000166473 | -0.04757666886702805 | [141] | [87] | 0 | hSpCas9 | negative selection | 11736105 | 81168017 | 81168040 | 16 | + | 28162770 | HEL | viability | GGCGCCTCTGGTCCTCAGGGCGG | PKD1L2 | ENSG00000166473 | -1.9531119848635352 | [265] | [43] | -8 | hSpCas9 | negative selection | 11736106 | 81167933 | 81167956 | 16 | - | 28162770 | HEL | viability | CAGACCAGAAGAGCCTGCGGAGG | PKD1L2 | ENSG00000166473 | 0.7116861857178484 | [142] | [149] | 6 | hSpCas9 | negative selection | 11736107 | 81137476 | 81137499 | 16 | - | 28162770 | MV411 | viability | GAAGAGAGTGGACGATGAGGAGG | PKD1L2 | ENSG00000166473 | -0.7445251301518063 | [357] | [179] | -5 | hSpCas9 | negative selection | 11905469 | 81163599 | 81163622 | 16 | - | 28162770 | MV411 | viability | GAATCTGTCGGAGAATATCGAGG | PKD1L2 | ENSG00000166473 | -0.12154736816536094 | [482] | [373] | -1 | hSpCas9 | negative selection | 11905470 | 81117372 | 81117395 | 16 | - | 28162770 | MV411 | viability | GCGCTGCCGGAACCACAGGGAGG | PKD1L2 | ENSG00000166473 | 0.6035813610080507 | [99] | [127] | 5 | hSpCas9 | negative selection | 11905471 | 81168017 | 81168040 | 16 | + | 28162770 | MV411 | viability | GGCGCCTCTGGTCCTCAGGGCGG | PKD1L2 | ENSG00000166473 | -3.5938647031981668 | [214] | [14] | -9 | hSpCas9 | negative selection | 11905472 | 81167933 | 81167956 | 16 | - | 28162770 | MV411 | viability | CAGACCAGAAGAGCCTGCGGAGG | PKD1L2 | ENSG00000166473 | 1.3662737802926261 | [98] | [214] | 9 | hSpCas9 | negative selection | 11905473 | 81137476 | 81137499 | 16 | - | 28162770 | MONOMAC1 | viability | GAAGAGAGTGGACGATGAGGAGG | PKD1L2 | ENSG00000166473 | 0.6059999184043615 | [238] | [416] | 6 | hSpCas9 | negative selection | 12074835 | 81163599 | 81163622 | 16 | - | 28162770 | MONOMAC1 | viability | GAATCTGTCGGAGAATATCGAGG | PKD1L2 | ENSG00000166473 | -0.17566319626698657 | [334] | [339] | -1 | hSpCas9 | negative selection | 12074836 | 81117372 | 81117395 | 16 | - | 28162770 | MONOMAC1 | viability | GCGCTGCCGGAACCACAGGGAGG | PKD1L2 | ENSG00000166473 | -0.8782146630400132 | [92] | [57] | -6 | hSpCas9 | negative selection | 12074837 | 81168017 | 81168040 | 16 | + | 28162770 | MONOMAC1 | viability | GGCGCCTCTGGTCCTCAGGGCGG | PKD1L2 | ENSG00000166473 | -1.5791824647810229 | [158] | [60] | -8 | hSpCas9 | negative selection | 12074838 | 81167933 | 81167956 | 16 | - | 28162770 | MONOMAC1 | viability | CAGACCAGAAGAGCCTGCGGAGG | PKD1L2 | ENSG00000166473 | 0.6296315500548844 | [105] | [187] | 6 | hSpCas9 | negative selection | 12074839 | 81137476 | 81137499 | 16 | - | 28162770 | OCIAML2 | viability | GAAGAGAGTGGACGATGAGGAGG | PKD1L2 | ENSG00000166473 | -0.5820511079105841 | [73] | [273] | -4 | hSpCas9 | negative selection | 12244201 | 81163599 | 81163622 | 16 | - | 28162770 | OCIAML2 | viability | GAATCTGTCGGAGAATATCGAGG | PKD1L2 | ENSG00000166473 | 0.5812519664560336 | [98] | [820] | 5 | hSpCas9 | negative selection | 12244202 | 81117372 | 81117395 | 16 | - | 28162770 | OCIAML2 | viability | GCGCTGCCGGAACCACAGGGAGG | PKD1L2 | ENSG00000166473 | 0.6317318923875166 | [16] | [145] | 6 | hSpCas9 | negative selection | 12244203 | 81168017 | 81168040 | 16 | + | 28162770 | OCIAML2 | viability | GGCGCCTCTGGTCCTCAGGGCGG | PKD1L2 | ENSG00000166473 | -2.1006802154918556 | [64] | [83] | -8 | hSpCas9 | negative selection | 12244204 | 81167933 | 81167956 | 16 | - | 28162770 | OCIAML2 | viability | CAGACCAGAAGAGCCTGCGGAGG | PKD1L2 | ENSG00000166473 | 0.9407964204843037 | [24] | [265] | 8 | hSpCas9 | negative selection | 12244205 | 81137476 | 81137499 | 16 | - | 28162770 | OCIAML3 | viability | GAAGAGAGTGGACGATGAGGAGG | PKD1L2 | ENSG00000166473 | 0.10643207781692893 | [71] | [233] | 1 | hSpCas9 | negative selection | 12413567 | 81163599 | 81163622 | 16 | - | 28162770 | OCIAML3 | viability | GAATCTGTCGGAGAATATCGAGG | PKD1L2 | ENSG00000166473 | -0.20169021754540284 | [103] | [272] | -1 | hSpCas9 | negative selection | 12413568 | 81117372 | 81117395 | 16 | - | 28162770 | OCIAML3 | viability | GCGCTGCCGGAACCACAGGGAGG | PKD1L2 | ENSG00000166473 | -0.5940076403241631 | [35] | [71] | -4 | hSpCas9 | negative selection | 12413569 | 81168017 | 81168040 | 16 | + | 28162770 | OCIAML3 | viability | GGCGCCTCTGGTCCTCAGGGCGG | PKD1L2 | ENSG00000166473 | -1.1744687488103787 | [79] | [106] | -7 | hSpCas9 | negative selection | 12413570 | 81167933 | 81167956 | 16 | - | 28162770 | OCIAML3 | viability | CAGACCAGAAGAGCCTGCGGAGG | PKD1L2 | ENSG00000166473 | 0.9465607410385396 | [32] | [191] | 7 | hSpCas9 | negative selection | 12413571 |