Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:5585
• Symbol:PKN1
• Description:protein kinase N1

DataSource: http://genomecrispr.dkfz.de/#!/results/PKN1

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
14441282	14441305	19	+	26472758	Jiyoye	viability	AGGGTGCTGAGAACCTGCGGCGG	PKN1	ENSG00000123143	0.3556450808657914	[170]	[164]	2	hSpCas9	negative selection	121355
14446540	14446563	19	+	26472758	Jiyoye	viability	GCAGCCCCGGATGACACCCAAGG	PKN1	ENSG00000123143	-0.9620584281598454	[92]	[35]	-6	hSpCas9	negative selection	121356
14451000	14451023	19	+	26472758	Jiyoye	viability	GCTGCGAGAAGAGCTCGCTGCGG	PKN1	ENSG00000123143	-1.177787119215283	[125]	[41]	-7	hSpCas9	negative selection	121357
14451026	14451049	19	-	26472758	Jiyoye	viability	GCGGGTGCTGAAGGCAGCGGAGG	PKN1	ENSG00000123143	0.05274464693118161	[100]	[78]	0	hSpCas9	negative selection	121358
14441205	14441228	19	-	26472758	Jiyoye	viability	CCAGCTGCTGCTGTACCCCGGGG	PKN1	ENSG00000123143	-0.03298671192858649	[250]	[184]	0	hSpCas9	negative selection	121359
14441244	14441267	19	+	26472758	Jiyoye	viability	GCTGCGGCGGGAAATCCGCAAGG	PKN1	ENSG00000123143	-0.44244801342979456	[354]	[196]	-3	hSpCas9	negative selection	121360
14441262	14441285	19	+	26472758	Jiyoye	viability	CAAGGAGCTGAAGCTGAAGGAGG	PKN1	ENSG00000123143	-1.6762406266817642	[177]	[41]	-8	hSpCas9	negative selection	121361
14441306	14441329	19	-	26472758	Jiyoye	viability	GCTGCGGCCCAGGTCAGTGGTGG	PKN1	ENSG00000123143	1.179764885402801	[47]	[81]	7	hSpCas9	negative selection	121362
14441367	14441390	19	-	26472758	Jiyoye	viability	GCTGGTGCAGCAGGTCGAGGCGG	PKN1	ENSG00000123143	-0.5928246184941264	[69]	[34]	-4	hSpCas9	negative selection	121363
14441408	14441431	19	-	26472758	Jiyoye	viability	CGGGTCGGGAAGCACCACGTGGG	PKN1	ENSG00000123143	-0.9988169781699635	[105]	[39]	-6	hSpCas9	negative selection	121364
14441282	14441305	19	+	26472758	KBM7	viability	AGGGTGCTGAGAACCTGCGGCGG	PKN1	ENSG00000123143	0.8350558243861369	[514,375]	[519,234]	8	hSpCas9	negative selection	312473
14446540	14446563	19	+	26472758	KBM7	viability	GCAGCCCCGGATGACACCCAAGG	PKN1	ENSG00000123143	0.195309839746457	[204,178]	[71,130]	2	hSpCas9	negative selection	312474
14451000	14451023	19	+	26472758	KBM7	viability	GCTGCGAGAAGAGCTCGCTGCGG	PKN1	ENSG00000123143	-1.3362817330922654	[462,344]	[74,73]	-7	hSpCas9	negative selection	312475
14451026	14451049	19	-	26472758	KBM7	viability	GCGGGTGCTGAAGGCAGCGGAGG	PKN1	ENSG00000123143	-1.5661119827095782	[562,286]	[16,108]	-8	hSpCas9	negative selection	312476
14441205	14441228	19	-	26472758	KBM7	viability	CCAGCTGCTGCTGTACCCCGGGG	PKN1	ENSG00000123143	0.4210015680320187	[836,389]	[454,300]	4	hSpCas9	negative selection	312477
14441244	14441267	19	+	26472758	KBM7	viability	GCTGCGGCGGGAAATCCGCAAGG	PKN1	ENSG00000123143	0.7221589231015955	[965,461]	[743,350]	7	hSpCas9	negative selection	312478
14441262	14441285	19	+	26472758	KBM7	viability	CAAGGAGCTGAAGCTGAAGGAGG	PKN1	ENSG00000123143	0.14999795773842078	[704,527]	[318,317]	1	hSpCas9	negative selection	312479
14441306	14441329	19	-	26472758	KBM7	viability	GCTGCGGCCCAGGTCAGTGGTGG	PKN1	ENSG00000123143	-0.07366704740978797	[385,390]	[239,115]	0	hSpCas9	negative selection	312480
14441367	14441390	19	-	26472758	KBM7	viability	GCTGGTGCAGCAGGTCGAGGCGG	PKN1	ENSG00000123143	0.8539184108085155	[241,269]	[156,275]	8	hSpCas9	negative selection	312481
14441408	14441431	19	-	26472758	KBM7	viability	CGGGTCGGGAAGCACCACGTGGG	PKN1	ENSG00000123143	0.6247123761223945	[444,284]	[335,191]	6	hSpCas9	negative selection	312482
14441282	14441305	19	+	26472758	Raji	viability	AGGGTGCTGAGAACCTGCGGCGG	PKN1	ENSG00000123143	-0.18104764752567573	[297]	[60]	-1	hSpCas9	negative selection	503591
14446540	14446563	19	+	26472758	Raji	viability	GCAGCCCCGGATGACACCCAAGG	PKN1	ENSG00000123143	0.33479403147667197	[81]	[23]	3	hSpCas9	negative selection	503592
14451000	14451023	19	+	26472758	Raji	viability	GCTGCGAGAAGAGCTCGCTGCGG	PKN1	ENSG00000123143	-1.0997743722676883	[156]	[16]	-7	hSpCas9	negative selection	503593
14451026	14451049	19	-	26472758	Raji	viability	GCGGGTGCTGAAGGCAGCGGAGG	PKN1	ENSG00000123143	-0.9181515567335382	[227]	[27]	-6	hSpCas9	negative selection	503594
14441205	14441228	19	-	26472758	Raji	viability	CCAGCTGCTGCTGTACCCCGGGG	PKN1	ENSG00000123143	0.7772349336812687	[263]	[104]	7	hSpCas9	negative selection	503595
14441244	14441267	19	+	26472758	Raji	viability	GCTGCGGCGGGAAATCCGCAAGG	PKN1	ENSG00000123143	0.10338160481610326	[360]	[89]	1	hSpCas9	negative selection	503596
14441262	14441285	19	+	26472758	Raji	viability	CAAGGAGCTGAAGCTGAAGGAGG	PKN1	ENSG00000123143	-0.43124025068068694	[336]	[57]	-4	hSpCas9	negative selection	503597
14441306	14441329	19	-	26472758	Raji	viability	GCTGCGGCCCAGGTCAGTGGTGG	PKN1	ENSG00000123143	-0.20271912411697313	[242]	[48]	-2	hSpCas9	negative selection	503598
14441367	14441390	19	-	26472758	Raji	viability	GCTGGTGCAGCAGGTCGAGGCGG	PKN1	ENSG00000123143	-1.0540798873205168	[169]	[18]	-6	hSpCas9	negative selection	503599
14441408	14441431	19	-	26472758	Raji	viability	CGGGTCGGGAAGCACCACGTGGG	PKN1	ENSG00000123143	-0.35579048494951454	[192]	[34]	-3	hSpCas9	negative selection	503600
14441282	14441305	19	+	26472758	K562	viability	AGGGTGCTGAGAACCTGCGGCGG	PKN1	ENSG00000123143	-2.241008099503795	[503]	[89]	-7	hSpCas9	negative selection	694709
14446540	14446563	19	+	26472758	K562	viability	GCAGCCCCGGATGACACCCAAGG	PKN1	ENSG00000123143	0.0054115924791025005	[130]	[110]	0	hSpCas9	negative selection	694710
14451000	14451023	19	+	26472758	K562	viability	GCTGCGAGAAGAGCTCGCTGCGG	PKN1	ENSG00000123143	-2.552047878248421	[263]	[37]	-8	hSpCas9	negative selection	694711
14451026	14451049	19	-	26472758	K562	viability	GCGGGTGCTGAAGGCAGCGGAGG	PKN1	ENSG00000123143	-4.751476874000817	[350]	[10]	-9	hSpCas9	negative selection	694712
14441205	14441228	19	-	26472758	K562	viability	CCAGCTGCTGCTGTACCCCGGGG	PKN1	ENSG00000123143	0.37117586995238566	[391]	[427]	3	hSpCas9	negative selection	694713
14441244	14441267	19	+	26472758	K562	viability	GCTGCGGCGGGAAATCCGCAAGG	PKN1	ENSG00000123143	0.5160920517741132	[554]	[669]	4	hSpCas9	negative selection	694714
14441262	14441285	19	+	26472758	K562	viability	CAAGGAGCTGAAGCTGAAGGAGG	PKN1	ENSG00000123143	0.09612640800565664	[603]	[544]	0	hSpCas9	negative selection	694715
14441306	14441329	19	-	26472758	K562	viability	GCTGCGGCCCAGGTCAGTGGTGG	PKN1	ENSG00000123143	0.08120707031056965	[401]	[358]	0	hSpCas9	negative selection	694716
14441367	14441390	19	-	26472758	K562	viability	GCTGGTGCAGCAGGTCGAGGCGG	PKN1	ENSG00000123143	0.8804554129818724	[221]	[344]	7	hSpCas9	negative selection	694717
14441408	14441431	19	-	26472758	K562	viability	CGGGTCGGGAAGCACCACGTGGG	PKN1	ENSG00000123143	0.7080364073903523	[218]	[301]	6	hSpCas9	negative selection	694718
14441244	14441267	19	+	26627737	DLD1	viability	GCTGCGGCGGGAAATCCGCAAGG	PKN1	ENSG00000123143	1.2539284479783408	[21]	[9,25,13]	9	hSpCas9	negative selection	802908
14443589	14443612	19	+	26627737	DLD1	viability	ATGATCCAGACCTACAGCAATGG	PKN1	ENSG00000123143	0.35173773503969863	[753]	[288,249,352]	3	hSpCas9	negative selection	802910
14446488	14446511	19	+	26627737	DLD1	viability	CATCCGCATGCAACTCCGCCGGG	PKN1	ENSG00000123143	-0.26462747717342416	[295]	[145,28,56]	-3	hSpCas9	negative selection	802912
14450370	14450393	19	+	26627737	DLD1	viability	CTTCCGAGTGGAGCACGCGGTGG	PKN1	ENSG00000123143	0.5580429157304754	[597]	[208,444,191]	5	hSpCas9	negative selection	802913
14451058	14451081	19	-	26627737	DLD1	viability	CTGTAGTGCGTGGCGGGAAAGGG	PKN1	ENSG00000123143	0.7550016792517105	[1147]	[693,601,531]	7	hSpCas9	negative selection	802914
14451862	14451885	19	+	26627737	DLD1	viability	ACCTCCCAGAGACCATCCCGTGG	PKN1	ENSG00000123143	0.18020466832816462	[583]	[135,281,205]	1	hSpCas9	negative selection	802915
14441244	14441267	19	+	26627737	GBM cells	viability after 5 days	GCTGCGGCGGGAAATCCGCAAGG	PKN1	ENSG00000123143	-2.5605177437516122	[10]	[0,0]	-9	hSpCas9	negative selection	885223
14443589	14443612	19	+	26627737	GBM cells	viability after 5 days	ATGATCCAGACCTACAGCAATGG	PKN1	ENSG00000123143	-0.27380666107458196	[451]	[180,219]	-4	hSpCas9	negative selection	885225
14446488	14446511	19	+	26627737	GBM cells	viability after 5 days	CATCCGCATGCAACTCCGCCGGG	PKN1	ENSG00000123143	-0.22370541177827008	[134]	[39,83]	-3	hSpCas9	negative selection	885227
14450370	14450393	19	+	26627737	GBM cells	viability after 5 days	CTTCCGAGTGGAGCACGCGGTGG	PKN1	ENSG00000123143	-0.24467697874316408	[189]	[94,76]	-4	hSpCas9	negative selection	885228
14451058	14451081	19	-	26627737	GBM cells	viability after 5 days	CTGTAGTGCGTGGCGGGAAAGGG	PKN1	ENSG00000123143	-0.0342727727645078	[653]	[368,315]	0	hSpCas9	negative selection	885229
14451862	14451885	19	+	26627737	GBM cells	viability after 5 days	ACCTCCCAGAGACCATCCCGTGG	PKN1	ENSG00000123143	0.020592431473937967	[374]	[236,170]	0	hSpCas9	negative selection	885230
14441244	14441267	19	+	26627737	GBM cells	viability after 13 days	GCTGCGGCGGGAAATCCGCAAGG	PKN1	ENSG00000123143	-1.5773284950588504	[10]	[1,1]	-9	hSpCas9	negative selection	967538
14443589	14443612	19	+	26627737	GBM cells	viability after 13 days	ATGATCCAGACCTACAGCAATGG	PKN1	ENSG00000123143	-0.248694447684913	[451]	[276,148]	-3	hSpCas9	negative selection	967540
14446488	14446511	19	+	26627737	GBM cells	viability after 13 days	CATCCGCATGCAACTCCGCCGGG	PKN1	ENSG00000123143	0.46360403567198066	[134]	[116,87]	6	hSpCas9	negative selection	967542
14450370	14450393	19	+	26627737	GBM cells	viability after 13 days	CTTCCGAGTGGAGCACGCGGTGG	PKN1	ENSG00000123143	-0.06688580747469974	[189]	[109,88]	-1	hSpCas9	negative selection	967543
14451058	14451081	19	-	26627737	GBM cells	viability after 13 days	CTGTAGTGCGTGGCGGGAAAGGG	PKN1	ENSG00000123143	0.03395049409810591	[653]	[477,269]	0	hSpCas9	negative selection	967544
14451862	14451885	19	+	26627737	GBM cells	viability after 13 days	ACCTCCCAGAGACCATCCCGTGG	PKN1	ENSG00000123143	0.10716024980305328	[374]	[254,189]	1	hSpCas9	negative selection	967545
14441244	14441267	19	+	26627737	GBM cells	viability after 21 days	GCTGCGGCGGGAAATCCGCAAGG	PKN1	ENSG00000123143	-1.2701515154310092	[10]	[2,1]	-8	hSpCas9	negative selection	1049853
14443589	14443612	19	+	26627737	GBM cells	viability after 21 days	ATGATCCAGACCTACAGCAATGG	PKN1	ENSG00000123143	-0.4049295538658086	[451]	[197,173]	-4	hSpCas9	negative selection	1049855
14446488	14446511	19	+	26627737	GBM cells	viability after 21 days	CATCCGCATGCAACTCCGCCGGG	PKN1	ENSG00000123143	0.1964982541849143	[134]	[82,84]	2	hSpCas9	negative selection	1049857
14450370	14450393	19	+	26627737	GBM cells	viability after 21 days	CTTCCGAGTGGAGCACGCGGTGG	PKN1	ENSG00000123143	-1.2603783169381715	[189]	[40,44]	-8	hSpCas9	negative selection	1049858
14451058	14451081	19	-	26627737	GBM cells	viability after 21 days	CTGTAGTGCGTGGCGGGAAAGGG	PKN1	ENSG00000123143	-0.18771683377326798	[653]	[312,310]	-2	hSpCas9	negative selection	1049859
14451862	14451885	19	+	26627737	GBM cells	viability after 21 days	ACCTCCCAGAGACCATCCCGTGG	PKN1	ENSG00000123143	0.10016875842902273	[374]	[232,204]	1	hSpCas9	negative selection	1049860
14441244	14441267	19	+	26627737	RPE1	viability after 9 days	GCTGCGGCGGGAAATCCGCAAGG	PKN1	ENSG00000123143	0.4593181055139146	[40]	[28,2]	3	hSpCas9	negative selection	1132168
14443589	14443612	19	+	26627737	RPE1	viability after 9 days	ATGATCCAGACCTACAGCAATGG	PKN1	ENSG00000123143	-0.09562662317281245	[1537]	[385,533]	0	hSpCas9	negative selection	1132170
14446488	14446511	19	+	26627737	RPE1	viability after 9 days	CATCCGCATGCAACTCCGCCGGG	PKN1	ENSG00000123143	-1.4395573993379966	[1158]	[114,157]	-8	hSpCas9	negative selection	1132172
14450370	14450393	19	+	26627737	RPE1	viability after 9 days	CTTCCGAGTGGAGCACGCGGTGG	PKN1	ENSG00000123143	0.46285179167984436	[617]	[222,322]	3	hSpCas9	negative selection	1132173
14451058	14451081	19	-	26627737	RPE1	viability after 9 days	CTGTAGTGCGTGGCGGGAAAGGG	PKN1	ENSG00000123143	0.5571067888750298	[1940]	[804,1008]	4	hSpCas9	negative selection	1132174
14451862	14451885	19	+	26627737	RPE1	viability after 9 days	ACCTCCCAGAGACCATCCCGTGG	PKN1	ENSG00000123143	-0.7885317411226604	[1033]	[234,125]	-5	hSpCas9	negative selection	1132175
14441244	14441267	19	+	26627737	RPE1	viability after 12 days	GCTGCGGCGGGAAATCCGCAAGG	PKN1	ENSG00000123143	0.8058811712919463	[40]	[27,9]	5	hSpCas9	negative selection	1214483
14443589	14443612	19	+	26627737	RPE1	viability after 12 days	ATGATCCAGACCTACAGCAATGG	PKN1	ENSG00000123143	-0.23199954001856748	[1537]	[515,177]	-1	hSpCas9	negative selection	1214485
14446488	14446511	19	+	26627737	RPE1	viability after 12 days	CATCCGCATGCAACTCCGCCGGG	PKN1	ENSG00000123143	-0.7378649355955048	[1158]	[142,232]	-5	hSpCas9	negative selection	1214487
14450370	14450393	19	+	26627737	RPE1	viability after 12 days	CTTCCGAGTGGAGCACGCGGTGG	PKN1	ENSG00000123143	0.42073435839824763	[617]	[298,140]	3	hSpCas9	negative selection	1214488
14451058	14451081	19	-	26627737	RPE1	viability after 12 days	CTGTAGTGCGTGGCGGGAAAGGG	PKN1	ENSG00000123143	0.7325115905702271	[1940]	[881,849]	5	hSpCas9	negative selection	1214489
14451862	14451885	19	+	26627737	RPE1	viability after 12 days	ACCTCCCAGAGACCATCCCGTGG	PKN1	ENSG00000123143	-1.3618770145373873	[1033]	[144,68]	-7	hSpCas9	negative selection	1214490
14441244	14441267	19	+	26627737	RPE1	viability after 15 days	GCTGCGGCGGGAAATCCGCAAGG	PKN1	ENSG00000123143	0.35533449625544034	[40]	[23,5]	2	hSpCas9	negative selection	1296798
14443589	14443612	19	+	26627737	RPE1	viability after 15 days	ATGATCCAGACCTACAGCAATGG	PKN1	ENSG00000123143	0.27534138748045234	[1537]	[832,230]	1	hSpCas9	negative selection	1296800
14446488	14446511	19	+	26627737	RPE1	viability after 15 days	CATCCGCATGCAACTCCGCCGGG	PKN1	ENSG00000123143	-1.1416520298608415	[1158]	[114,180]	-6	hSpCas9	negative selection	1296802
14450370	14450393	19	+	26627737	RPE1	viability after 15 days	CTTCCGAGTGGAGCACGCGGTGG	PKN1	ENSG00000123143	0.28941732410288223	[617]	[204,221]	2	hSpCas9	negative selection	1296803
14451058	14451081	19	-	26627737	RPE1	viability after 15 days	CTGTAGTGCGTGGCGGGAAAGGG	PKN1	ENSG00000123143	0.8987213384474004	[1940]	[956,1087]	5	hSpCas9	negative selection	1296804
14451862	14451885	19	+	26627737	RPE1	viability after 15 days	ACCTCCCAGAGACCATCCCGTGG	PKN1	ENSG00000123143	-1.1550414514066796	[1033]	[139,122]	-6	hSpCas9	negative selection	1296805
14441244	14441267	19	+	26627737	RPE1	viability after 18 days	GCTGCGGCGGGAAATCCGCAAGG	PKN1	ENSG00000123143	0.08655962286219587	[40]	[18,3]	0	hSpCas9	negative selection	1379113
14443589	14443612	19	+	26627737	RPE1	viability after 18 days	ATGATCCAGACCTACAGCAATGG	PKN1	ENSG00000123143	0.0007183429103420069	[1537]	[626,188]	0	hSpCas9	negative selection	1379115
14446488	14446511	19	+	26627737	RPE1	viability after 18 days	CATCCGCATGCAACTCCGCCGGG	PKN1	ENSG00000123143	-0.7831192036590727	[1158]	[130,235]	-5	hSpCas9	negative selection	1379117
14450370	14450393	19	+	26627737	RPE1	viability after 18 days	CTTCCGAGTGGAGCACGCGGTGG	PKN1	ENSG00000123143	0.8722151037041255	[617]	[298,311]	5	hSpCas9	negative selection	1379118
14451058	14451081	19	-	26627737	RPE1	viability after 18 days	CTGTAGTGCGTGGCGGGAAAGGG	PKN1	ENSG00000123143	1.0723841916063725	[1940]	[1087,1115]	6	hSpCas9	negative selection	1379119
14451862	14451885	19	+	26627737	RPE1	viability after 18 days	ACCTCCCAGAGACCATCCCGTGG	PKN1	ENSG00000123143	-1.6956249079732792	[1033]	[104,65]	-7	hSpCas9	negative selection	1379120
14441244	14441267	19	+	26627737	HeLa	viability after 8 days	GCTGCGGCGGGAAATCCGCAAGG	PKN1	ENSG00000123143	-0.6474694957264122	[214]	[126,51,17]	-6	hSpCas9	negative selection	1461428
14443589	14443612	19	+	26627737	HeLa	viability after 8 days	ATGATCCAGACCTACAGCAATGG	PKN1	ENSG00000123143	-0.172963256809883	[651]	[263,231,260]	-2	hSpCas9	negative selection	1461430
14446488	14446511	19	+	26627737	HeLa	viability after 8 days	CATCCGCATGCAACTCCGCCGGG	PKN1	ENSG00000123143	0.5234408960823335	[167]	[1,295,1]	4	hSpCas9	negative selection	1461432
14450370	14450393	19	+	26627737	HeLa	viability after 8 days	CTTCCGAGTGGAGCACGCGGTGG	PKN1	ENSG00000123143	1.8532623323029265	[70]	[168,88,90]	9	hSpCas9	negative selection	1461433
14451058	14451081	19	-	26627737	HeLa	viability after 8 days	CTGTAGTGCGTGGCGGGAAAGGG	PKN1	ENSG00000123143	0.2272590087249451	[1120]	[749,617,396]	2	hSpCas9	negative selection	1461434
14451862	14451885	19	+	26627737	HeLa	viability after 8 days	ACCTCCCAGAGACCATCCCGTGG	PKN1	ENSG00000123143	0.35216880506382187	[474]	[471,244,129]	3	hSpCas9	negative selection	1461435
14441244	14441267	19	+	26627737	HeLa	viability after 12 days	GCTGCGGCGGGAAATCCGCAAGG	PKN1	ENSG00000123143	-0.13132907035318064	[214]	[87,76,78]	-1	hSpCas9	negative selection	1543743
14443589	14443612	19	+	26627737	HeLa	viability after 12 days	ATGATCCAGACCTACAGCAATGG	PKN1	ENSG00000123143	0.13939444305743764	[651]	[560,230,112]	1	hSpCas9	negative selection	1543745
14446488	14446511	19	+	26627737	HeLa	viability after 12 days	CATCCGCATGCAACTCCGCCGGG	PKN1	ENSG00000123143	-0.027511485215631737	[167]	[35,156,0]	0	hSpCas9	negative selection	1543747
14450370	14450393	19	+	26627737	HeLa	viability after 12 days	CTTCCGAGTGGAGCACGCGGTGG	PKN1	ENSG00000123143	1.8452295935584577	[70]	[104,107,102]	9	hSpCas9	negative selection	1543748
14451058	14451081	19	-	26627737	HeLa	viability after 12 days	CTGTAGTGCGTGGCGGGAAAGGG	PKN1	ENSG00000123143	0.38647855828762645	[1120]	[856,341,652]	3	hSpCas9	negative selection	1543749
14451862	14451885	19	+	26627737	HeLa	viability after 12 days	ACCTCCCAGAGACCATCCCGTGG	PKN1	ENSG00000123143	0.2906726114438054	[474]	[440,156,136]	2	hSpCas9	negative selection	1543750
14441244	14441267	19	+	26627737	HeLa	viability after 15 days	GCTGCGGCGGGAAATCCGCAAGG	PKN1	ENSG00000123143	0.10959334742351667	[214]	[53,84,148]	1	hSpCas9	negative selection	1626058
14443589	14443612	19	+	26627737	HeLa	viability after 15 days	ATGATCCAGACCTACAGCAATGG	PKN1	ENSG00000123143	-0.2992061400822772	[651]	[340,58,247]	-3	hSpCas9	negative selection	1626060
14446488	14446511	19	+	26627737	HeLa	viability after 15 days	CATCCGCATGCAACTCCGCCGGG	PKN1	ENSG00000123143	-0.5120712101958997	[167]	[69,68,0]	-4	hSpCas9	negative selection	1626062
14450370	14450393	19	+	26627737	HeLa	viability after 15 days	CTTCCGAGTGGAGCACGCGGTGG	PKN1	ENSG00000123143	2.153280523570362	[70]	[175,81,126]	9	hSpCas9	negative selection	1626063
14451058	14451081	19	-	26627737	HeLa	viability after 15 days	CTGTAGTGCGTGGCGGGAAAGGG	PKN1	ENSG00000123143	0.6640799893622054	[1120]	[590,664,930]	5	hSpCas9	negative selection	1626064
14451862	14451885	19	+	26627737	HeLa	viability after 15 days	ACCTCCCAGAGACCATCCCGTGG	PKN1	ENSG00000123143	-0.28998722601665805	[474]	[297,60,109]	-2	hSpCas9	negative selection	1626065
14441244	14441267	19	+	26627737	HeLa	viability after 18 days	GCTGCGGCGGGAAATCCGCAAGG	PKN1	ENSG00000123143	0.09904640991592817	[214]	[35,68,148]	0	hSpCas9	negative selection	1708373
14443589	14443612	19	+	26627737	HeLa	viability after 18 days	ATGATCCAGACCTACAGCAATGG	PKN1	ENSG00000123143	-0.2621499884876067	[651]	[237,50,247]	-2	hSpCas9	negative selection	1708375
14446488	14446511	19	+	26627737	HeLa	viability after 18 days	CATCCGCATGCAACTCCGCCGGG	PKN1	ENSG00000123143	-0.40588332040723385	[167]	[50,60,0]	-4	hSpCas9	negative selection	1708377
14450370	14450393	19	+	26627737	HeLa	viability after 18 days	CTTCCGAGTGGAGCACGCGGTGG	PKN1	ENSG00000123143	2.162430170475559	[70]	[117,69,126]	9	hSpCas9	negative selection	1708378
14451058	14451081	19	-	26627737	HeLa	viability after 18 days	CTGTAGTGCGTGGCGGGAAAGGG	PKN1	ENSG00000123143	0.6446140731732071	[1120]	[378,548,930]	5	hSpCas9	negative selection	1708379
14451862	14451885	19	+	26627737	HeLa	viability after 18 days	ACCTCCCAGAGACCATCCCGTGG	PKN1	ENSG00000123143	-0.2391055222863634	[474]	[208,52,109]	-2	hSpCas9	negative selection	1708380
14441244	14441267	19	+	26627737	HCT116	viability after 6 days	GCTGCGGCGGGAAATCCGCAAGG	PKN1	ENSG00000123143	0.47540062123594995	[246]	[140,5]	2	hSpCas9	negative selection	1790688
14443589	14443612	19	+	26627737	HCT116	viability after 6 days	ATGATCCAGACCTACAGCAATGG	PKN1	ENSG00000123143	0.05401436167212381	[900]	[264,81]	0	hSpCas9	negative selection	1790690
14446488	14446511	19	+	26627737	HCT116	viability after 6 days	CATCCGCATGCAACTCCGCCGGG	PKN1	ENSG00000123143	2.620919173696552	[254]	[127,311]	9	hSpCas9	negative selection	1790692
14450370	14450393	19	+	26627737	HCT116	viability after 6 days	CTTCCGAGTGGAGCACGCGGTGG	PKN1	ENSG00000123143	1.4452766260610574	[899]	[1063,10]	7	hSpCas9	negative selection	1790693
14451058	14451081	19	-	26627737	HCT116	viability after 6 days	CTGTAGTGCGTGGCGGGAAAGGG	PKN1	ENSG00000123143	1.1251683401981951	[809]	[260,286]	6	hSpCas9	negative selection	1790694
14451862	14451885	19	+	26627737	HCT116	viability after 6 days	ACCTCCCAGAGACCATCCCGTGG	PKN1	ENSG00000123143	2.574385047348777	[956]	[1432,599]	9	hSpCas9	negative selection	1790695
14441244	14441267	19	+	26627737	HCT116	viability after 8 days	GCTGCGGCGGGAAATCCGCAAGG	PKN1	ENSG00000123143	-0.030337080186655263	[168]	[97,110,64]	0	hSpCas9	negative selection	1873003
14443589	14443612	19	+	26627737	HCT116	viability after 8 days	ATGATCCAGACCTACAGCAATGG	PKN1	ENSG00000123143	-0.3768817152087368	[700]	[414,140,337]	-4	hSpCas9	negative selection	1873005
14446488	14446511	19	+	26627737	HCT116	viability after 8 days	CATCCGCATGCAACTCCGCCGGG	PKN1	ENSG00000123143	-0.8745687801240101	[282]	[80,81,91]	-8	hSpCas9	negative selection	1873007
14450370	14450393	19	+	26627737	HCT116	viability after 8 days	CTTCCGAGTGGAGCACGCGGTGG	PKN1	ENSG00000123143	-0.857763024691292	[444]	[154,175,75]	-8	hSpCas9	negative selection	1873008
14451058	14451081	19	-	26627737	HCT116	viability after 8 days	CTGTAGTGCGTGGCGGGAAAGGG	PKN1	ENSG00000123143	-0.09352338772584945	[1055]	[549,609,476]	-1	hSpCas9	negative selection	1873009
14451862	14451885	19	+	26627737	HCT116	viability after 8 days	ACCTCCCAGAGACCATCCCGTGG	PKN1	ENSG00000123143	0.1998266624409325	[382]	[220,196,307]	2	hSpCas9	negative selection	1873010
14441244	14441267	19	+	26627737	HCT116	viability after 9 days	GCTGCGGCGGGAAATCCGCAAGG	PKN1	ENSG00000123143	-1.1653679446098195	[246]	[15,39]	-7	hSpCas9	negative selection	1955318
14443589	14443612	19	+	26627737	HCT116	viability after 9 days	ATGATCCAGACCTACAGCAATGG	PKN1	ENSG00000123143	0.41035625331327596	[900]	[388,264]	3	hSpCas9	negative selection	1955320
14446488	14446511	19	+	26627737	HCT116	viability after 9 days	CATCCGCATGCAACTCCGCCGGG	PKN1	ENSG00000123143	0.7816674659332292	[254]	[44,173]	5	hSpCas9	negative selection	1955322
14450370	14450393	19	+	26627737	HCT116	viability after 9 days	CTTCCGAGTGGAGCACGCGGTGG	PKN1	ENSG00000123143	-0.6063274099098935	[899]	[39,250]	-4	hSpCas9	negative selection	1955323
14451058	14451081	19	-	26627737	HCT116	viability after 9 days	CTGTAGTGCGTGGCGGGAAAGGG	PKN1	ENSG00000123143	1.2449622340115147	[809]	[892,211]	7	hSpCas9	negative selection	1955324
14451862	14451885	19	+	26627737	HCT116	viability after 9 days	ACCTCCCAGAGACCATCCCGTGG	PKN1	ENSG00000123143	0.23610482708722147	[956]	[367,247]	1	hSpCas9	negative selection	1955325
14441244	14441267	19	+	26627737	HCT116	viability after 12 days	GCTGCGGCGGGAAATCCGCAAGG	PKN1	ENSG00000123143	-0.15975388773775356	[168]	[92,65,77]	-2	hSpCas9	negative selection	2037633
14443589	14443612	19	+	26627737	HCT116	viability after 12 days	ATGATCCAGACCTACAGCAATGG	PKN1	ENSG00000123143	-0.27589956675740024	[700]	[342,204,358]	-3	hSpCas9	negative selection	2037635
14446488	14446511	19	+	26627737	HCT116	viability after 12 days	CATCCGCATGCAACTCCGCCGGG	PKN1	ENSG00000123143	-0.9758841802387479	[282]	[133,45,40]	-8	hSpCas9	negative selection	2037637
14450370	14450393	19	+	26627737	HCT116	viability after 12 days	CTTCCGAGTGGAGCACGCGGTGG	PKN1	ENSG00000123143	-0.6522859832962704	[444]	[97,195,157]	-6	hSpCas9	negative selection	2037638
14451058	14451081	19	-	26627737	HCT116	viability after 12 days	CTGTAGTGCGTGGCGGGAAAGGG	PKN1	ENSG00000123143	-0.07806810290086652	[1055]	[625,551,390]	-1	hSpCas9	negative selection	2037639
14451862	14451885	19	+	26627737	HCT116	viability after 12 days	ACCTCCCAGAGACCATCCCGTGG	PKN1	ENSG00000123143	-0.2508627753157984	[382]	[151,211,145]	-3	hSpCas9	negative selection	2037640
14441244	14441267	19	+	26627737	HCT116	viability after 15 days	GCTGCGGCGGGAAATCCGCAAGG	PKN1	ENSG00000123143	-0.910663618206103	[168]	[89,54,14]	-7	hSpCas9	negative selection	2119948
14443589	14443612	19	+	26627737	HCT116	viability after 15 days	ATGATCCAGACCTACAGCAATGG	PKN1	ENSG00000123143	-0.24752643949532072	[700]	[383,150,485]	-3	hSpCas9	negative selection	2119950
14446488	14446511	19	+	26627737	HCT116	viability after 15 days	CATCCGCATGCAACTCCGCCGGG	PKN1	ENSG00000123143	-0.7045001552776986	[282]	[150,100,53]	-6	hSpCas9	negative selection	2119952
14450370	14450393	19	+	26627737	HCT116	viability after 15 days	CTTCCGAGTGGAGCACGCGGTGG	PKN1	ENSG00000123143	-0.5648259735868224	[444]	[134,229,148]	-5	hSpCas9	negative selection	2119953
14451058	14451081	19	-	26627737	HCT116	viability after 15 days	CTGTAGTGCGTGGCGGGAAAGGG	PKN1	ENSG00000123143	-0.08810080155291677	[1055]	[682,614,428]	-1	hSpCas9	negative selection	2119954
14451862	14451885	19	+	26627737	HCT116	viability after 15 days	ACCTCCCAGAGACCATCCCGTGG	PKN1	ENSG00000123143	0.49763974608563866	[382]	[284,369,273]	5	hSpCas9	negative selection	2119955
14441244	14441267	19	+	26627737	HCT116	viability after 18 days	GCTGCGGCGGGAAATCCGCAAGG	PKN1	ENSG00000123143	-0.12968090789486475	[168]	[113,75,31]	-1	hSpCas9	negative selection	2202263
14443589	14443612	19	+	26627737	HCT116	viability after 18 days	ATGATCCAGACCTACAGCAATGG	PKN1	ENSG00000123143	-0.026308869645564448	[700]	[457,189,360]	0	hSpCas9	negative selection	2202265
14446488	14446511	19	+	26627737	HCT116	viability after 18 days	CATCCGCATGCAACTCCGCCGGG	PKN1	ENSG00000123143	-0.7306578501716261	[282]	[90,21,140]	-6	hSpCas9	negative selection	2202267
14450370	14450393	19	+	26627737	HCT116	viability after 18 days	CTTCCGAGTGGAGCACGCGGTGG	PKN1	ENSG00000123143	-0.5027277568034787	[444]	[157,127,171]	-4	hSpCas9	negative selection	2202268
14451058	14451081	19	-	26627737	HCT116	viability after 18 days	CTGTAGTGCGTGGCGGGAAAGGG	PKN1	ENSG00000123143	-0.14334513313863284	[1055]	[473,454,457]	-1	hSpCas9	negative selection	2202269
14451862	14451885	19	+	26627737	HCT116	viability after 18 days	ACCTCCCAGAGACCATCCCGTGG	PKN1	ENSG00000123143	0.35032710964504954	[382]	[90,296,319]	3	hSpCas9	negative selection	2202270
14441138	14441161	19	+	24336569	HL60	viability	CGCAGAGTGAGCCTCGCAGCTGG	PKN1	ENSG00000123143	0.26658305522234804	[415]	[1058]	2	hSpCas9	negative selection	2284393
14441149	14441172	19	-	24336569	HL60	viability	TCTAGCAGGGACCAGCTGCGAGG	PKN1	ENSG00000123143	1.1743748038006934	[267]	[1279]	8	hSpCas9	negative selection	2284394
14441157	14441180	19	+	24336569	HL60	viability	CTGGTCCCTGCTAGAGCAGCTGG	PKN1	ENSG00000123143	-0.7510862267802009	[714]	[898]	-6	hSpCas9	negative selection	2284395
14441162	14441185	19	-	24336569	HL60	viability	CAGGCCCAGCTGCTCTAGCAGGG	PKN1	ENSG00000123143	1.4946124368606717	[189]	[1132]	8	hSpCas9	negative selection	2284396
14441167	14441190	19	+	24336569	HL60	viability	CTAGAGCAGCTGGGCCTGGCCGG	PKN1	ENSG00000123143	0.44463718625036414	[616]	[1776]	4	hSpCas9	negative selection	2284397
14441211	14441234	19	+	24336569	HL60	viability	GGTACAGCAGCAGCTGGAGCTGG	PKN1	ENSG00000123143	-0.7444291133513258	[930]	[1175]	-6	hSpCas9	negative selection	2284398
14441222	14441245	19	+	24336569	HL60	viability	AGCTGGAGCTGGAGCGGGAGCGG	PKN1	ENSG00000123143	0.0798386864712125	[633]	[1417]	0	hSpCas9	negative selection	2284399
14441231	14441254	19	+	24336569	HL60	viability	TGGAGCGGGAGCGGCTGCGGCGG	PKN1	ENSG00000123143	0.3639159690820466	[1087]	[2962]	3	hSpCas9	negative selection	2284400
14441244	14441267	19	+	24336569	HL60	viability	GCTGCGGCGGGAAATCCGCAAGG	PKN1	ENSG00000123143	-0.03912531188900248	[1191]	[2454]	0	hSpCas9	negative selection	2284401
14441259	14441282	19	+	24336569	HL60	viability	CCGCAAGGAGCTGAAGCTGAAGG	PKN1	ENSG00000123143	1.2478607223930178	[427]	[2150]	8	hSpCas9	negative selection	2284402
14441138	14441161	19	+	24336569	KBM7	viability	CGCAGAGTGAGCCTCGCAGCTGG	PKN1	ENSG00000123143	0.4622554025763338	[358]	[1348]	4	hSpCas9	negative selection	2351570
14441149	14441172	19	-	24336569	KBM7	viability	TCTAGCAGGGACCAGCTGCGAGG	PKN1	ENSG00000123143	-0.376341972634907	[404]	[850]	-3	hSpCas9	negative selection	2351571
14441157	14441180	19	+	24336569	KBM7	viability	CTGGTCCCTGCTAGAGCAGCTGG	PKN1	ENSG00000123143	1.3266365665490074	[345]	[2366]	9	hSpCas9	negative selection	2351572
14441162	14441185	19	-	24336569	KBM7	viability	CAGGCCCAGCTGCTCTAGCAGGG	PKN1	ENSG00000123143	-0.35565670710784314	[455]	[971]	-3	hSpCas9	negative selection	2351573
14441167	14441190	19	+	24336569	KBM7	viability	CTAGAGCAGCTGGGCCTGGCCGG	PKN1	ENSG00000123143	1.1030003101466102	[275]	[1616]	8	hSpCas9	negative selection	2351574
14441211	14441234	19	+	24336569	KBM7	viability	GGTACAGCAGCAGCTGGAGCTGG	PKN1	ENSG00000123143	-0.868232487429687	[428]	[640]	-6	hSpCas9	negative selection	2351575
14441222	14441245	19	+	24336569	KBM7	viability	AGCTGGAGCTGGAGCGGGAGCGG	PKN1	ENSG00000123143	-0.21011868215636587	[829]	[1956]	-2	hSpCas9	negative selection	2351576
14441231	14441254	19	+	24336569	KBM7	viability	TGGAGCGGGAGCGGCTGCGGCGG	PKN1	ENSG00000123143	0.3913826090714715	[702]	[2514]	3	hSpCas9	negative selection	2351577
14441244	14441267	19	+	24336569	KBM7	viability	GCTGCGGCGGGAAATCCGCAAGG	PKN1	ENSG00000123143	0.32811176688908494	[815]	[2793]	3	hSpCas9	negative selection	2351578
14441259	14441282	19	+	24336569	KBM7	viability	CCGCAAGGAGCTGAAGCTGAAGG	PKN1	ENSG00000123143	0.9941341959515685	[498]	[2710]	8	hSpCas9	negative selection	2351579
14465446	14465469	19	+	25494202	A375	resistance to PLX-4720 (puromycin)	GGAGTGCAGTGGCGTGATCTAGG	PKN1	ENSG00000123143	1.5299201678265226	[5,69]	[1,47]	6	dCas9-VP64	positive selection	2386495
14471344	14471367	19	-	25494202	A375	resistance to PLX-4720 (puromycin)	GGCCTGTAATCCCAGCACTTCGG	PKN1	ENSG00000123143	-0.9729140478390328	[44,104]	[3,11]	-6	dCas9-VP64	positive selection	2403868
14457771	14457794	19	-	25494202	A375	resistance to PLX-4720 (puromycin)	CACTTGAACCCAGGAGGCAGAGG	PKN1	ENSG00000123143	-1.4184778160092897	[54,284]	[10,16]	-7	dCas9-VP64	positive selection	2414575
14460406	14460429	19	+	25494202	A375	resistance to PLX-4720 (puromycin)	TCTCCCAGGCTGGAGTGCAGTGG	PKN1	ENSG00000123143	-0.49998316673352905	[290,357]	[69,28]	-2	dCas9-VP64	positive selection	2425353
14433154	14433177	19	+	25494202	A375	resistance to PLX-4720 (puromycin)	ACCCGGAAAGAGGAAAGGTGGGG	PKN1	ENSG00000123143	1.516072214659946	[12,15]	[5,11]	5	dCas9-VP64	positive selection	2431024
14433239	14433262	19	-	25494202	A375	resistance to PLX-4720 (puromycin)	GACGGGTTCCCAGAGGCCCCCGG	PKN1	ENSG00000123143	2.4159318664634055	[6,29]	[10,33]	7	dCas9-VP64	positive selection	2431025
14433175	14433198	19	+	25494202	A375	resistance to PLX-4720 (puromycin)	GGAGCCGATGGGGATGCTCCGGG	PKN1	ENSG00000123143	4.015982634229236	[3,3]	[3,25]	9	dCas9-VP64	positive selection	2431026
14453546	14453569	19	+	25494202	A375	resistance to PLX-4720 (puromycin)	AGAGAGGGAGGGAGGGAGGGAGG	PKN1	ENSG00000123143	0.9305428154912776	[3,4]	[0,1]	4	dCas9-VP64	positive selection	2467733
14440087	14440110	19	-	25494202	A375	resistance to PLX-4720 (puromycin)	CTAGAGAATGTCCAAGGTGCAGG	PKN1	ENSG00000123143	4.271865658585909	[341,28]	[1474,31]	9	dCas9-VP64	positive selection	2478238
14440136	14440159	19	+	25494202	A375	resistance to PLX-4720 (puromycin)	GTTTCATCTAGAGGAACAGGAGG	PKN1	ENSG00000123143	-2.323418002507073	[45,84]	[2,1]	-9	dCas9-VP64	positive selection	2478239
14440159	14440182	19	+	25494202	A375	resistance to PLX-4720 (puromycin)	TCCCTTAGATGCCCTGGAGTTGG	PKN1	ENSG00000123143	-0.8641445538744812	[172,125]	[19,14]	-5	dCas9-VP64	positive selection	2478240
14465446	14465469	19	+	25494202	A375	resistance to PLX-4720 (zeocin)	GGAGTGCAGTGGCGTGATCTAGG	PKN1	ENSG00000123143	0.46408056547853904	[52,55]	[23,24]	3	dCas9-VP64	positive selection	2481750
14471344	14471367	19	-	25494202	A375	resistance to PLX-4720 (zeocin)	GGCCTGTAATCCCAGCACTTCGG	PKN1	ENSG00000123143	-0.830617512401781	[195,36]	[28,13]	-7	dCas9-VP64	positive selection	2499123
14457771	14457794	19	-	25494202	A375	resistance to PLX-4720 (zeocin)	CACTTGAACCCAGGAGGCAGAGG	PKN1	ENSG00000123143	0.5761613238144463	[143,285]	[83,121]	4	dCas9-VP64	positive selection	2509830
14460406	14460429	19	+	25494202	A375	resistance to PLX-4720 (zeocin)	TCTCCCAGGCTGGAGTGCAGTGG	PKN1	ENSG00000123143	0.5593039216911941	[271,243]	[52,190]	4	dCas9-VP64	positive selection	2520608
14433154	14433177	19	+	25494202	A375	resistance to PLX-4720 (zeocin)	ACCCGGAAAGAGGAAAGGTGGGG	PKN1	ENSG00000123143	1.2043783644460586	[17,68]	[12,49]	7	dCas9-VP64	positive selection	2526279
14433239	14433262	19	-	25494202	A375	resistance to PLX-4720 (zeocin)	GACGGGTTCCCAGAGGCCCCCGG	PKN1	ENSG00000123143	-0.14267230055496286	[97,124]	[38,26]	-1	dCas9-VP64	positive selection	2526280
14433175	14433198	19	+	25494202	A375	resistance to PLX-4720 (zeocin)	GGAGCCGATGGGGATGCTCCGGG	PKN1	ENSG00000123143	0.03226302627163524	[74,13]	[27,1]	0	dCas9-VP64	positive selection	2526281
14453546	14453569	19	+	25494202	A375	resistance to PLX-4720 (zeocin)	AGAGAGGGAGGGAGGGAGGGAGG	PKN1	ENSG00000123143	0.5788861668152605	[2,6]	[2,1]	4	dCas9-VP64	positive selection	2562988
14440087	14440110	19	-	25494202	A375	resistance to PLX-4720 (zeocin)	CTAGAGAATGTCCAAGGTGCAGG	PKN1	ENSG00000123143	2.238996106244307	[125,33]	[228,27]	8	dCas9-VP64	positive selection	2573493
14440136	14440159	19	+	25494202	A375	resistance to PLX-4720 (zeocin)	GTTTCATCTAGAGGAACAGGAGG	PKN1	ENSG00000123143	-0.11093628374836494	[231,33]	[70,11]	-1	dCas9-VP64	positive selection	2573494
14440159	14440182	19	+	25494202	A375	resistance to PLX-4720 (zeocin)	TCCCTTAGATGCCCTGGAGTTGG	PKN1	ENSG00000123143	-0.9808882836620814	[229,321]	[52,37]	-8	dCas9-VP64	positive selection	2573495
14443562	14443585	19	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCTGAAGGTGAAGCAGGGGGCGG	PKN1	ENSG00000123143	-0.0726759218387106	[3,3]	[3,1]	-1	hSpCas9	positive selection	3011601
14450359	14450382	19	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCTGCGGCACCACTTCCGAGTGG	PKN1	ENSG00000123143	0.11255716178204223	[2,2]	[2,2]	2	hSpCas9	positive selection	3011602
14458048	14458071	19	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCTTAAGCTGGATAACACAGTGG	PKN1	ENSG00000123143	-0.15747336359221487	[3,3]	[3,1]	-2	hSpCas9	positive selection	3011603
14443525	14443548	19	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCTTCTCCAGGCCCGCCACGCGG	PKN1	ENSG00000123143	0.4640004922169398	[4,4]	[4,5]	8	hSpCas9	positive selection	3011604
14443562	14443585	19	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCTGAAGGTGAAGCAGGGGGCGG	PKN1	ENSG00000123143	-0.7885597766043438	[3,3]	[1,0]	-9	hSpCas9	positive selection	3079459
14450359	14450382	19	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCTGCGGCACCACTTCCGAGTGG	PKN1	ENSG00000123143	0.1597836610674135	[2,2]	[3,0]	3	hSpCas9	positive selection	3079460
14458048	14458071	19	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCTTAAGCTGGATAACACAGTGG	PKN1	ENSG00000123143	-0.44513453007056286	[3,3]	[3,0]	-6	hSpCas9	positive selection	3079461
14443525	14443548	19	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCTTCTCCAGGCCCGCCACGCGG	PKN1	ENSG00000123143	0.19864259632046988	[4,4]	[4,2]	3	hSpCas9	positive selection	3079462
14450367	14450390		+	24336571	A375	resistance to PLX after 7 days	CCACTTCCGAGTGGAGCACGCGG	PKN1	ENSG00000123143	-0.2034476979513038	[10,9]	[7,10]	-6	hSpCas9	positive selection	3135870
14450367	14450390		-	24336571	A375	resistance to PLX after 7 days	CCGCGTGCTCCACTCGGAAGTGG	PKN1	ENSG00000123143	-0.4550392403636767	[6,11]	[6,5]	-9	hSpCas9	positive selection	3135871
14446491	14446514		-	24336571	A375	resistance to PLX after 7 days	GCGCCCGGCGGAGTTGCATGCGG	PKN1	ENSG00000123143	-0.02831267302078344	[7,5]	[5,6]	-1	hSpCas9	positive selection	3135872
14446487	14446510		+	24336571	A375	resistance to PLX after 7 days	TCATCCGCATGCAACTCCGCCGG	PKN1	ENSG00000123143	0.1511328329504662	[28,29]	[33,30]	5	hSpCas9	positive selection	3135874
14450367	14450390		+	24336571	A375	resistance to PLX after 14 days	CCACTTCCGAGTGGAGCACGCGG	PKN1	ENSG00000123143	-0.8313332069542447	[13,11]	[3,1]	-8	hSpCas9	positive selection	3193663
14450367	14450390		-	24336571	A375	resistance to PLX after 14 days	CCGCGTGCTCCACTCGGAAGTGG	PKN1	ENSG00000123143	-0.030460601621181915	[5,5]	[1,1]	0	hSpCas9	positive selection	3193664
14446491	14446514		-	24336571	A375	resistance to PLX after 14 days	GCGCCCGGCGGAGTTGCATGCGG	PKN1	ENSG00000123143	0.17538196715541954	[5,5]	[2,2]	1	hSpCas9	positive selection	3193665
14446487	14446510		+	24336571	A375	resistance to PLX after 14 days	TCATCCGCATGCAACTCCGCCGG	PKN1	ENSG00000123143	-0.2616377225151283	[25,33]	[9,12]	-3	hSpCas9	positive selection	3193667
14450367	14450390		+	24336571	A375	viability after 7 days	CCACTTCCGAGTGGAGCACGCGG	PKN1	ENSG00000123143	0.3287114873576505	[8]	[10,9]	5	hSpCas9	negative selection	3251456
14450367	14450390		-	24336571	A375	viability after 7 days	CCGCGTGCTCCACTCGGAAGTGG	PKN1	ENSG00000123143	-0.07982770967400221	[9]	[6,11]	-1	hSpCas9	negative selection	3251457
14446491	14446514		-	24336571	A375	viability after 7 days	GCGCCCGGCGGAGTTGCATGCGG	PKN1	ENSG00000123143	-0.6186107866747483	[11]	[7,5]	-7	hSpCas9	negative selection	3251458
14446487	14446510		+	24336571	A375	viability after 7 days	TCATCCGCATGCAACTCCGCCGG	PKN1	ENSG00000123143	-0.9533619219339609	[59]	[28,29]	-8	hSpCas9	negative selection	3251460
14450367	14450390		+	24336571	A375	viability after 14 days	CCACTTCCGAGTGGAGCACGCGG	PKN1	ENSG00000123143	0.6488486947898078	[8]	[13,11]	8	hSpCas9	negative selection	3309249
14450367	14450390		-	24336571	A375	viability after 14 days	CCGCGTGCTCCACTCGGAAGTGG	PKN1	ENSG00000123143	-0.7038454441222813	[9]	[5,5]	-7	hSpCas9	negative selection	3309250
14446491	14446514		-	24336571	A375	viability after 14 days	GCGCCCGGCGGAGTTGCATGCGG	PKN1	ENSG00000123143	-0.855154267441288	[11]	[5,5]	-8	hSpCas9	negative selection	3309251
14446487	14446510		+	24336571	A375	viability after 14 days	TCATCCGCATGCAACTCCGCCGG	PKN1	ENSG00000123143	-0.8870787296138312	[59]	[25,33]	-8	hSpCas9	negative selection	3309253
14451088	14451111	19	+	27383988	293T	resistance to West Nile virus (flavivirus)	TGCAAGCCCGCGCCGCTCACAGG	PKN1	ENSG00000123143	-1.4008852713059596	[403,403]	[0,0]	-8	hSpCas9	positive selection	3386061
14450367	14450390	19	-	27383988	293T	resistance to West Nile virus (flavivirus)	CCGCGTGCTCCACTCGGAAGTGG	PKN1	ENSG00000123143	7.672363710724679	[122,122]	[163,163]	9	hSpCas9	positive selection	3386062
14451068	14451091	19	-	27383988	293T	resistance to West Nile virus (flavivirus)	GCACAGGGTGCTGTAGTGCGTGG	PKN1	ENSG00000123143	0.6874706031148871	[94,94]	[0,0]	3	hSpCas9	positive selection	3386063
14443561	14443584	19	+	26780180	HT29	viability (Avana library 4 designs)	GCTGAAGGTGAAGCAGGGGGCGG	PKN1	ENSG00000123143	0.984273732063617	[]	[]	4	hSpCas9	negative selection	3449692
14450358	14450381	19	+	26780180	HT29	viability (Avana library 4 designs)	GCTGCGGCACCACTTCCGAGTGG	PKN1	ENSG00000123143	1.17064398321018	[]	[]	4	hSpCas9	negative selection	3449693
14458047	14458070	19	+	26780180	HT29	viability (Avana library 4 designs)	GCTTAAGCTGGATAACACAGTGG	PKN1	ENSG00000123143	1.62506007580136	[]	[]	6	hSpCas9	negative selection	3449694
14443525	14443548	19	-	26780180	HT29	viability (Avana library 4 designs)	GCTTCTCCAGGCCCGCCACGCGG	PKN1	ENSG00000123143	-0.0871946755368618	[]	[]	-1	hSpCas9	negative selection	3449695
14443525	14443548	19	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCTTCTCCAGGCCCGCCACGCGG	PKN1	ENSG00000123143	4.13723285032187	[]	[]	6	hSpCas9	negative selection	3544574
14450358	14450381	19	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCTGCGGCACCACTTCCGAGTGG	PKN1	ENSG00000123143	5.71519084739779	[]	[]	9	hSpCas9	negative selection	3544575
14458047	14458070	19	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCTTAAGCTGGATAACACAGTGG	PKN1	ENSG00000123143	-4.9752545166248	[]	[]	-5	hSpCas9	negative selection	3544576
14443561	14443584	19	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCTGAAGGTGAAGCAGGGGGCGG	PKN1	ENSG00000123143	2.28837298793813	[]	[]	3	hSpCas9	negative selection	3544577
14441244	14441267	19	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCTGCGGCGGGAAATCCGCAAGG	PKN1	ENSG00000123143	-2.33935437836516	[]	[]	-3	hSpCas9	negative selection	3544578
14451000	14451023	19	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCTGCGAGAAGAGCTCGCTGCGG	PKN1	ENSG00000123143	0.126007507466497	[]	[]	0	hSpCas9	negative selection	3544579
14443525	14443548	19	-	26780180	A375	viability (Avana lentiGuide)	GCTTCTCCAGGCCCGCCACGCGG	PKN1	ENSG00000123143	0.275164582054957	[]	[]	0	hSpCas9	negative selection	3653233
14450358	14450381	19	+	26780180	A375	viability (Avana lentiGuide)	GCTGCGGCACCACTTCCGAGTGG	PKN1	ENSG00000123143	6.1162741097634	[]	[]	5	hSpCas9	negative selection	3653234
14458047	14458070	19	+	26780180	A375	viability (Avana lentiGuide)	GCTTAAGCTGGATAACACAGTGG	PKN1	ENSG00000123143	0.235683244038701	[]	[]	0	hSpCas9	negative selection	3653235
14443561	14443584	19	+	26780180	A375	viability (Avana lentiGuide)	GCTGAAGGTGAAGCAGGGGGCGG	PKN1	ENSG00000123143	4.1679776221311	[]	[]	4	hSpCas9	negative selection	3653236
14441244	14441267	19	+	26780180	A375	viability (Avana lentiGuide)	GCTGCGGCGGGAAATCCGCAAGG	PKN1	ENSG00000123143	4.30734501567861	[]	[]	4	hSpCas9	negative selection	3653237
14451000	14451023	19	+	26780180	A375	viability (Avana lentiGuide)	GCTGCGAGAAGAGCTCGCTGCGG	PKN1	ENSG00000123143	23.8511282962403	[]	[]	9	hSpCas9	negative selection	3653238
14443525	14443548	19	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCTTCTCCAGGCCCGCCACGCGG	PKN1	ENSG00000123143	0.18104791120284083	[5]	[6,5]	5	hSpCas9	positive selection	3761892
14450358	14450381	19	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCTGCGGCACCACTTCCGAGTGG	PKN1	ENSG00000123143	0.0034017225040850474	[3]	[3,3]	0	hSpCas9	positive selection	3761893
14458047	14458070	19	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCTTAAGCTGGATAACACAGTGG	PKN1	ENSG00000123143	-0.41203257323620085	[5]	[2,4]	-6	hSpCas9	positive selection	3761894
14443561	14443584	19	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCTGAAGGTGAAGCAGGGGGCGG	PKN1	ENSG00000123143	-0.012669610960137412	[3]	[3,3]	0	hSpCas9	positive selection	3761895
14441244	14441267	19	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCTGCGGCGGGAAATCCGCAAGG	PKN1	ENSG00000123143	-0.5609989035886431	[3]	[1,2]	-7	hSpCas9	positive selection	3761896
14451000	14451023	19	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCTGCGAGAAGAGCTCGCTGCGG	PKN1	ENSG00000123143	-0.5149829031733637	[4]	[3,1]	-6	hSpCas9	positive selection	3761897
14443525	14443548	19	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCTTCTCCAGGCCCGCCACGCGG	PKN1	ENSG00000123143	0.18978264693817729	[6]	[6,6]	4	hSpCas9	positive selection	3870499
14450358	14450381	19	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCTGCGGCACCACTTCCGAGTGG	PKN1	ENSG00000123143	-0.9202233443080444	[4]	[1,1]	-8	hSpCas9	positive selection	3870500
14458047	14458070	19	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCTTAAGCTGGATAACACAGTGG	PKN1	ENSG00000123143	-0.19993610274298257	[5]	[4,3]	-3	hSpCas9	positive selection	3870501
14443561	14443584	19	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCTGAAGGTGAAGCAGGGGGCGG	PKN1	ENSG00000123143	0.00749595274034115	[4]	[3,4]	0	hSpCas9	positive selection	3870502
14441244	14441267	19	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCTGCGGCGGGAAATCCGCAAGG	PKN1	ENSG00000123143	0.06580746682458433	[4]	[2,5]	1	hSpCas9	positive selection	3870503
14451000	14451023	19	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCTGCGAGAAGAGCTCGCTGCGG	PKN1	ENSG00000123143	-0.6129404991408993	[4]	[0,3]	-7	hSpCas9	positive selection	3870504
14450367	14450390	19	+	26780180	A375	viability	CCACTTCCGAGTGGAGCACGCGG	PKN1	ENSG00000123143	1.84481491999818	[]	[]	9	hSpCas9	negative selection	3981316
14450367	14450390	19	-	26780180	A375	viability	CCGCGTGCTCCACTCGGAAGTGG	PKN1	ENSG00000123143	0.909131637925861	[]	[]	4	hSpCas9	negative selection	3981317
14451068	14451091	19	-	26780180	A375	viability	GCACAGGGTGCTGTAGTGCGTGG	PKN1	ENSG00000123143	1.1918900397905	[]	[]	6	hSpCas9	negative selection	3981318
14446491	14446514	19	-	26780180	A375	viability	GCGCCCGGCGGAGTTGCATGCGG	PKN1	ENSG00000123143	0.642726488628913	[]	[]	2	hSpCas9	negative selection	3981319
14446487	14446510	19	+	26780180	A375	viability	TCATCCGCATGCAACTCCGCCGG	PKN1	ENSG00000123143	2.14047451046625	[]	[]	9	hSpCas9	negative selection	3981320
14451088	14451111	19	+	26780180	A375	viability	TGCAAGCCCGCGCCGCTCACAGG	PKN1	ENSG00000123143	1.59410658237047	[]	[]	8	hSpCas9	negative selection	3981321
14450367	14450390	19	+	26780180	HT29	viability (GeCKOv2 library)	CCACTTCCGAGTGGAGCACGCGG	PKN1	ENSG00000123143	1.6514653831682	[]	[]	8	hSpCas9	negative selection	4089282
14450367	14450390	19	-	26780180	HT29	viability (GeCKOv2 library)	CCGCGTGCTCCACTCGGAAGTGG	PKN1	ENSG00000123143	1.30216400607901	[]	[]	6	hSpCas9	negative selection	4089283
14451068	14451091	19	-	26780180	HT29	viability (GeCKOv2 library)	GCACAGGGTGCTGTAGTGCGTGG	PKN1	ENSG00000123143	1.718001476228	[]	[]	8	hSpCas9	negative selection	4089284
14446491	14446514	19	-	26780180	HT29	viability (GeCKOv2 library)	GCGCCCGGCGGAGTTGCATGCGG	PKN1	ENSG00000123143	0.551268729639633	[]	[]	1	hSpCas9	negative selection	4089285
14446487	14446510	19	+	26780180	HT29	viability (GeCKOv2 library)	TCATCCGCATGCAACTCCGCCGG	PKN1	ENSG00000123143	1.45835525607792	[]	[]	7	hSpCas9	negative selection	4089286
14451088	14451111	19	+	26780180	HT29	viability (GeCKOv2 library)	TGCAAGCCCGCGCCGCTCACAGG	PKN1	ENSG00000123143	0.977738272557815	[]	[]	4	hSpCas9	negative selection	4089287
14450367	14450390	19	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CCACTTCCGAGTGGAGCACGCGG	PKN1	ENSG00000123143	-0.29424869772050183	[3]	[1,1]	-6	hSpCas9	positive selection	4160848
14450367	14450390	19	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CCGCGTGCTCCACTCGGAAGTGG	PKN1	ENSG00000123143	-0.2676552337187892	[2]	[1,0]	-6	hSpCas9	positive selection	4160849
14446491	14446514	19	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GCGCCCGGCGGAGTTGCATGCGG	PKN1	ENSG00000123143	-0.4388891884964428	[3]	[1,1]	-8	hSpCas9	positive selection	4160850
14446487	14446510	19	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TCATCCGCATGCAACTCCGCCGG	PKN1	ENSG00000123143	0.008662459706103964	[4]	[2,3]	0	hSpCas9	positive selection	4160852
14450367	14450390	19	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CCACTTCCGAGTGGAGCACGCGG	PKN1	ENSG00000123143	-0.19027433965720647	[2]	[0,2,0,0]	-3	hSpCas9	positive selection	4224870
14450367	14450390	19	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CCGCGTGCTCCACTCGGAAGTGG	PKN1	ENSG00000123143	-0.22628756138636819	[2]	[0,1,0,0]	-3	hSpCas9	positive selection	4224871
14446491	14446514	19	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GCGCCCGGCGGAGTTGCATGCGG	PKN1	ENSG00000123143	0.554861960113687	[2]	[2,2,2,0]	4	hSpCas9	positive selection	4224872
14446487	14446510	19	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TCATCCGCATGCAACTCCGCCGG	PKN1	ENSG00000123143	0.9707329257811966	[5]	[4,3,4,4]	6	hSpCas9	positive selection	4224874
14450367	14450390	19	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCACTTCCGAGTGGAGCACGCGG	PKN1	ENSG00000123143	-0.07894904600913519	[3]	[2,1]	-1	hSpCas9	positive selection	4290486
14446487	14446510	19	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TCATCCGCATGCAACTCCGCCGG	PKN1	ENSG00000123143	-0.470627898724857	[4]	[3,1]	-8	hSpCas9	positive selection	4290487
14446491	14446514	19	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GCGCCCGGCGGAGTTGCATGCGG	PKN1	ENSG00000123143	-0.09136125126593642	[1]	[0,0]	-2	hSpCas9	positive selection	4290488
14451088	14451111	19	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TGCAAGCCCGCGCCGCTCACAGG	PKN1	ENSG00000123143	0.22907467571969248	[4]	[4,3]	4	hSpCas9	positive selection	4354738
14450367	14450390	19	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCGCGTGCTCCACTCGGAAGTGG	PKN1	ENSG00000123143	-0.5048127315010627	[3]	[2,0]	-8	hSpCas9	positive selection	4354739
14451068	14451091	19	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GCACAGGGTGCTGTAGTGCGTGG	PKN1	ENSG00000123143	-0.15262205244787802	[1]	[1,0]	-3	hSpCas9	positive selection	4354740
14446488	14446510	19	+	27760321	OCIAML3	viability	CATCCGCATGCAACTCCGCCGG	PKN1	ENSG00000123143	-0.3246945339678836	[1056,824]	[501,689]	-3	hSpCas9	negative selection	4428151
14450972	14450994	19	+	27760321	OCIAML3	viability	TGCCCGCCGACCACCCCAAGGG	PKN1	ENSG00000123143	0.37256191804078154	[726,547]	[525,788]	4	hSpCas9	negative selection	4428152
14451083	14451105	19	-	27760321	OCIAML3	viability	AGCGGCGCGGGCTTGCACAGGG	PKN1	ENSG00000123143	-0.023242897955741207	[523,425]	[367,357]	0	hSpCas9	negative selection	4428153
14451892	14451914	19	+	27760321	OCIAML3	viability	CCCCCTCAATGGGGGGACCTGG	PKN1	ENSG00000123143	0.4223366286021501	[447,355]	[370,480]	5	hSpCas9	negative selection	4428154
14451953	14451975	19	-	27760321	OCIAML3	viability	GCTTCGGCTGTAAAGGCCCCGG	PKN1	ENSG00000123143	-0.2854333579402085	[641,536]	[305,468]	-3	hSpCas9	negative selection	4428155
14446488	14446510	19	+	27760321	OCIAML2	viability	CATCCGCATGCAACTCCGCCGG	PKN1	ENSG00000123143	0.2277258727573801	[1056,824]	[757,1052]	3	hSpCas9	negative selection	4511614
14450972	14450994	19	+	27760321	OCIAML2	viability	TGCCCGCCGACCACCCCAAGGG	PKN1	ENSG00000123143	-0.09744721959721542	[726,547]	[427,543]	-1	hSpCas9	negative selection	4511615
14451083	14451105	19	-	27760321	OCIAML2	viability	AGCGGCGCGGGCTTGCACAGGG	PKN1	ENSG00000123143	-0.06134140988266553	[523,425]	[314,433]	-1	hSpCas9	negative selection	4511616
14451892	14451914	19	+	27760321	OCIAML2	viability	CCCCCTCAATGGGGGGACCTGG	PKN1	ENSG00000123143	0.3026575621470236	[447,355]	[364,442]	4	hSpCas9	negative selection	4511617
14451953	14451975	19	-	27760321	OCIAML2	viability	GCTTCGGCTGTAAAGGCCCCGG	PKN1	ENSG00000123143	0.1319494871974412	[641,536]	[412,661]	1	hSpCas9	negative selection	4511618
14446488	14446510	19	+	27760321	MV411	viability	CATCCGCATGCAACTCCGCCGG	PKN1	ENSG00000123143	-0.0361182646428857	[1056,824]	[690,466]	0	hSpCas9	negative selection	4595077
14450972	14450994	19	+	27760321	MV411	viability	TGCCCGCCGACCACCCCAAGGG	PKN1	ENSG00000123143	-0.8451795600004675	[726,547]	[41,517]	-5	hSpCas9	negative selection	4595078
14451083	14451105	19	-	27760321	MV411	viability	AGCGGCGCGGGCTTGCACAGGG	PKN1	ENSG00000123143	0.9858995711643121	[523,425]	[846,272]	7	hSpCas9	negative selection	4595079
14451892	14451914	19	+	27760321	MV411	viability	CCCCCTCAATGGGGGGACCTGG	PKN1	ENSG00000123143	0.9304923665986043	[447,355]	[641,292]	6	hSpCas9	negative selection	4595080
14451953	14451975	19	-	27760321	MV411	viability	GCTTCGGCTGTAAAGGCCCCGG	PKN1	ENSG00000123143	0.18595045318786857	[641,536]	[373,540]	1	hSpCas9	negative selection	4595081
14446488	14446510	19	+	27760321	HL60	viability	CATCCGCATGCAACTCCGCCGG	PKN1	ENSG00000123143	-0.17967127158535523	[1056,824]	[641,707]	-2	hSpCas9	negative selection	4678540
14450972	14450994	19	+	27760321	HL60	viability	TGCCCGCCGACCACCCCAAGGG	PKN1	ENSG00000123143	0.3414324812943015	[726,547]	[616,693]	4	hSpCas9	negative selection	4678541
14451083	14451105	19	-	27760321	HL60	viability	AGCGGCGCGGGCTTGCACAGGG	PKN1	ENSG00000123143	0.06783963857966949	[523,425]	[390,418]	0	hSpCas9	negative selection	4678542
14451892	14451914	19	+	27760321	HL60	viability	CCCCCTCAATGGGGGGACCTGG	PKN1	ENSG00000123143	-0.42862410744489665	[447,355]	[208,277]	-5	hSpCas9	negative selection	4678543
14451953	14451975	19	-	27760321	HL60	viability	GCTTCGGCTGTAAAGGCCCCGG	PKN1	ENSG00000123143	-0.1111670113304496	[641,536]	[461,424]	-1	hSpCas9	negative selection	4678544
14446488	14446510	19	+	27760321	HT1080	viability	CATCCGCATGCAACTCCGCCGG	PKN1	ENSG00000123143	-1.5189641053091605	[824,643]	[40,168]	-5	hSpCas9	negative selection	4762003
14450972	14450994	19	+	27760321	HT1080	viability	TGCCCGCCGACCACCCCAAGGG	PKN1	ENSG00000123143	1.3051416785639536	[547,427]	[604,343]	7	hSpCas9	negative selection	4762004
14451083	14451105	19	-	27760321	HT1080	viability	AGCGGCGCGGGCTTGCACAGGG	PKN1	ENSG00000123143	0.9422102640079529	[425,332]	[174,416]	5	hSpCas9	negative selection	4762005
14451892	14451914	19	+	27760321	HT1080	viability	CCCCCTCAATGGGGGGACCTGG	PKN1	ENSG00000123143	1.5829998844735864	[355,277]	[332,427]	8	hSpCas9	negative selection	4762006
14451953	14451975	19	-	27760321	HT1080	viability	GCTTCGGCTGTAAAGGCCCCGG	PKN1	ENSG00000123143	0.16942667554170543	[536,418]	[153,279]	0	hSpCas9	negative selection	4762007
14446488	14446510	19	+	27760321	HT29	viability after 7 days	CATCCGCATGCAACTCCGCCGG	PKN1	ENSG00000123143	0.016626300534735794	[824,643]	[888,816,1142]	0	hSpCas9	negative selection	4845466
14450972	14450994	19	+	27760321	HT29	viability after 7 days	TGCCCGCCGACCACCCCAAGGG	PKN1	ENSG00000123143	0.3253907395166441	[547,427]	[1098,609,695]	5	hSpCas9	negative selection	4845467
14451083	14451105	19	-	27760321	HT29	viability after 7 days	AGCGGCGCGGGCTTGCACAGGG	PKN1	ENSG00000123143	0.021377227396891046	[425,332]	[678,296,533]	0	hSpCas9	negative selection	4845468
14451892	14451914	19	+	27760321	HT29	viability after 7 days	CCCCCTCAATGGGGGGACCTGG	PKN1	ENSG00000123143	-0.6409188865901735	[355,277]	[392,257,154]	-7	hSpCas9	negative selection	4845469
14451953	14451975	19	-	27760321	HT29	viability after 7 days	GCTTCGGCTGTAAAGGCCCCGG	PKN1	ENSG00000123143	-0.21655115857951707	[536,418]	[725,611,283]	-3	hSpCas9	negative selection	4845470
14446488	14446510	19	+	27760321	HT29	viability after 25 days	CATCCGCATGCAACTCCGCCGG	PKN1	ENSG00000123143	0.11036465936552875	[824,643]	[1028,845,825]	1	hSpCas9	negative selection	4928929
14450972	14450994	19	+	27760321	HT29	viability after 25 days	TGCCCGCCGACCACCCCAAGGG	PKN1	ENSG00000123143	0.6012779550567988	[547,427]	[448,1068,1066]	6	hSpCas9	negative selection	4928930
14451083	14451105	19	-	27760321	HT29	viability after 25 days	AGCGGCGCGGGCTTGCACAGGG	PKN1	ENSG00000123143	0.7206534305058625	[425,332]	[689,410,1081]	7	hSpCas9	negative selection	4928931
14451892	14451914	19	+	27760321	HT29	viability after 25 days	CCCCCTCAATGGGGGGACCTGG	PKN1	ENSG00000123143	0.6044851497491481	[355,277]	[643,612,369]	6	hSpCas9	negative selection	4928932
14451953	14451975	19	-	27760321	HT29	viability after 25 days	GCTTCGGCTGTAAAGGCCCCGG	PKN1	ENSG00000123143	0.003503342494078354	[536,418]	[420,490,759]	0	hSpCas9	negative selection	4928933
14446488	14446510	19	+	27760321	HT29	viability after 22 days	CATCCGCATGCAACTCCGCCGG	PKN1	ENSG00000123143	-0.07226188412287338	[824,643]	[1047,602,764]	0	hSpCas9	negative selection	5012392
14450972	14450994	19	+	27760321	HT29	viability after 22 days	TGCCCGCCGACCACCCCAAGGG	PKN1	ENSG00000123143	0.6210275569804804	[547,427]	[831,1007,762]	7	hSpCas9	negative selection	5012393
14451083	14451105	19	-	27760321	HT29	viability after 22 days	AGCGGCGCGGGCTTGCACAGGG	PKN1	ENSG00000123143	0.5911624708641023	[425,332]	[578,653,752]	6	hSpCas9	negative selection	5012394
14451892	14451914	19	+	27760321	HT29	viability after 22 days	CCCCCTCAATGGGGGGACCTGG	PKN1	ENSG00000123143	0.19762205065310967	[355,277]	[419,507,331]	2	hSpCas9	negative selection	5012395
14451953	14451975	19	-	27760321	HT29	viability after 22 days	GCTTCGGCTGTAAAGGCCCCGG	PKN1	ENSG00000123143	0.06366475343587996	[536,418]	[498,515,720]	0	hSpCas9	negative selection	5012396
14446488	14446510	19	+	27760321	HT29	viability after 19 days	CATCCGCATGCAACTCCGCCGG	PKN1	ENSG00000123143	0.006595617292010303	[824,643]	[748,789,976]	0	hSpCas9	negative selection	5095855
14450972	14450994	19	+	27760321	HT29	viability after 19 days	TGCCCGCCGACCACCCCAAGGG	PKN1	ENSG00000123143	0.6275584735131201	[547,427]	[1145,982,500]	6	hSpCas9	negative selection	5095856
14451083	14451105	19	-	27760321	HT29	viability after 19 days	AGCGGCGCGGGCTTGCACAGGG	PKN1	ENSG00000123143	0.6766491537278536	[425,332]	[661,569,839]	7	hSpCas9	negative selection	5095857
14451892	14451914	19	+	27760321	HT29	viability after 19 days	CCCCCTCAATGGGGGGACCTGG	PKN1	ENSG00000123143	0.8992841226582036	[355,277]	[869,515,662]	8	hSpCas9	negative selection	5095858
14451953	14451975	19	-	27760321	HT29	viability after 19 days	GCTTCGGCTGTAAAGGCCCCGG	PKN1	ENSG00000123143	-0.49209102134694094	[536,418]	[406,433,328]	-4	hSpCas9	negative selection	5095859
14446488	14446510	19	+	27760321	HT29	viability after 16 days	CATCCGCATGCAACTCCGCCGG	PKN1	ENSG00000123143	0.12390473833668691	[824,643]	[1062,668,975]	1	hSpCas9	negative selection	5179318
14450972	14450994	19	+	27760321	HT29	viability after 16 days	TGCCCGCCGACCACCCCAAGGG	PKN1	ENSG00000123143	0.7973310920190915	[547,427]	[1138,621,1111]	8	hSpCas9	negative selection	5179319
14451083	14451105	19	-	27760321	HT29	viability after 16 days	AGCGGCGCGGGCTTGCACAGGG	PKN1	ENSG00000123143	0.5338063412676741	[425,332]	[763,547,547]	6	hSpCas9	negative selection	5179320
14451892	14451914	19	+	27760321	HT29	viability after 16 days	CCCCCTCAATGGGGGGACCTGG	PKN1	ENSG00000123143	0.5581201496451071	[355,277]	[620,286,673]	6	hSpCas9	negative selection	5179321
14451953	14451975	19	-	27760321	HT29	viability after 16 days	GCTTCGGCTGTAAAGGCCCCGG	PKN1	ENSG00000123143	-0.07008811799375142	[536,418]	[623,432,483]	-1	hSpCas9	negative selection	5179322
14446488	14446510	19	+	27760321	HT29	viability after 13 days	CATCCGCATGCAACTCCGCCGG	PKN1	ENSG00000123143	0.08448664713049814	[824,643]	[1073,835,805]	1	hSpCas9	negative selection	5262781
14450972	14450994	19	+	27760321	HT29	viability after 13 days	TGCCCGCCGACCACCCCAAGGG	PKN1	ENSG00000123143	0.5192872898221168	[547,427]	[815,820,797]	6	hSpCas9	negative selection	5262782
14451083	14451105	19	-	27760321	HT29	viability after 13 days	AGCGGCGCGGGCTTGCACAGGG	PKN1	ENSG00000123143	0.4036774270410399	[425,332]	[665,462,615]	5	hSpCas9	negative selection	5262783
14451892	14451914	19	+	27760321	HT29	viability after 13 days	CCCCCTCAATGGGGGGACCTGG	PKN1	ENSG00000123143	0.3432264584036483	[355,277]	[574,437,390]	4	hSpCas9	negative selection	5262784
14451953	14451975	19	-	27760321	HT29	viability after 13 days	GCTTCGGCTGTAAAGGCCCCGG	PKN1	ENSG00000123143	0.17004163127933314	[536,418]	[608,696,568]	2	hSpCas9	negative selection	5262785
14446488	14446510	19	+	27760321	HT29	viability after 10 days	CATCCGCATGCAACTCCGCCGG	PKN1	ENSG00000123143	-0.07060619461824913	[824,643]	[1005,1080,545]	-1	hSpCas9	negative selection	5346244
14450972	14450994	19	+	27760321	HT29	viability after 10 days	TGCCCGCCGACCACCCCAAGGG	PKN1	ENSG00000123143	0.6648073125806282	[547,427]	[1099,1049,754]	8	hSpCas9	negative selection	5346245
14451083	14451105	19	-	27760321	HT29	viability after 10 days	AGCGGCGCGGGCTTGCACAGGG	PKN1	ENSG00000123143	0.47038362940112066	[425,332]	[810,496,656]	6	hSpCas9	negative selection	5346246
14451892	14451914	19	+	27760321	HT29	viability after 10 days	CCCCCTCAATGGGGGGACCTGG	PKN1	ENSG00000123143	0.11629240585848956	[355,277]	[541,377,366]	1	hSpCas9	negative selection	5346247
14451953	14451975	19	-	27760321	HT29	viability after 10 days	GCTTCGGCTGTAAAGGCCCCGG	PKN1	ENSG00000123143	0.018199885379897696	[536,418]	[580,493,731]	0	hSpCas9	negative selection	5346248
14446488	14446510	19	+	27760321	MOLM13	viability	CATCCGCATGCAACTCCGCCGG	PKN1	ENSG00000123143	0.24248929525481744	[1056,824]	[935,357]	1	hSpCas9	negative selection	5429707
14450972	14450994	19	+	27760321	MOLM13	viability	TGCCCGCCGACCACCCCAAGGG	PKN1	ENSG00000123143	-0.3441410427313444	[726,547]	[253,303]	-2	hSpCas9	negative selection	5429708
14451083	14451105	19	-	27760321	MOLM13	viability	AGCGGCGCGGGCTTGCACAGGG	PKN1	ENSG00000123143	-0.07584280587197033	[523,425]	[488,51]	0	hSpCas9	negative selection	5429709
14451892	14451914	19	+	27760321	MOLM13	viability	CCCCCTCAATGGGGGGACCTGG	PKN1	ENSG00000123143	0.5441905869870549	[447,355]	[567,124]	4	hSpCas9	negative selection	5429710
14451953	14451975	19	-	27760321	MOLM13	viability	GCTTCGGCTGTAAAGGCCCCGG	PKN1	ENSG00000123143	1.2795336577048815	[641,536]	[290,1240]	8	hSpCas9	negative selection	5429711
14433525	14433548	19	+	27661255	K562	viability	GCCAGCGACGCCGTGCAGGTAGG	PKN1	ENSG00000123143	-0.048904675718800084	[184,203]	[177,125]	-2	dCas9-KRAB	negative selection	5502182
14433634	14433657	19	+	27661255	K562	viability	GAACGGGACTCGGGTGACGATGG	PKN1	ENSG00000123143	0.0892791396857211	[536,604]	[555,422]	3	dCas9-KRAB	negative selection	5502183
14433640	14433663	19	+	27661255	K562	viability	GACTCGGGTGACGATGGCAAGGG	PKN1	ENSG00000123143	-0.007610791895584557	[1201,1131]	[964,896]	0	dCas9-KRAB	negative selection	5502184
14440278	14440301	19	+	27661255	K562	viability	GCCCGGACCCAGGATGGCGGAGG	PKN1	ENSG00000123143	0.30658907884140685	[570,555]	[597,521]	8	dCas9-KRAB	negative selection	5502185
14440293	14440316	19	+	27661255	K562	viability	GGCGGAGGCCAATAACCCCTCGG	PKN1	ENSG00000123143	0.2141714144371736	[720,969]	[862,707]	7	dCas9-KRAB	negative selection	5502186
14440708	14440731	19	+	27661255	K562	viability	GGGTACAAGTGAGGGAAGATGGG	PKN1	ENSG00000123143	0.20657915987673747	[147,203]	[163,158]	7	dCas9-KRAB	negative selection	5502187
14450367	14450390	19	+	27260156	BXPC3	viability	CCACTTCCGAGTGGAGCACGCGG	PKN1	ENSG00000123143	0.20019302452553756	[493]	[503,477,641,786]	4	hSpCas9	negative selection	5562946
14446487	14446510	19	+	27260156	BXPC3	viability	TCATCCGCATGCAACTCCGCCGG	PKN1	ENSG00000123143	-0.324230686657329	[1853]	[1347,1527,1658,1689]	-6	hSpCas9	negative selection	5562947
14446491	14446514	19	-	27260156	BXPC3	viability	GCGCCCGGCGGAGTTGCATGCGG	PKN1	ENSG00000123143	0.564826003284336	[94]	[144,112,172,159]	9	hSpCas9	negative selection	5562948
14451088	14451111	19	+	27260156	BXPC3	viability	TGCAAGCCCGCGCCGCTCACAGG	PKN1	ENSG00000123143	0.05334866337346411	[1015]	[1031,1021,1109,1270]	1	hSpCas9	negative selection	5627198
14450367	14450390	19	-	27260156	BXPC3	viability	CCGCGTGCTCCACTCGGAAGTGG	PKN1	ENSG00000123143	-0.1795874528562063	[463]	[371,392,464,497]	-4	hSpCas9	negative selection	5627199
14451068	14451091	19	-	27260156	BXPC3	viability	GCACAGGGTGCTGTAGTGCGTGG	PKN1	ENSG00000123143	-0.2400301942471097	[183]	[154,130,212,153]	-5	hSpCas9	negative selection	5627200
14450367	14450390	19	+	27260156	A673	viability	CCACTTCCGAGTGGAGCACGCGG	PKN1	ENSG00000123143	0.14531477976046486	[493]	[804,586,598,650]	3	hSpCas9	negative selection	5684197
14446487	14446510	19	+	27260156	A673	viability	TCATCCGCATGCAACTCCGCCGG	PKN1	ENSG00000123143	-0.18740562583237264	[1853]	[2084,1911,1891,1942]	-5	hSpCas9	negative selection	5684198
14446491	14446514	19	-	27260156	A673	viability	GCGCCCGGCGGAGTTGCATGCGG	PKN1	ENSG00000123143	0.08380990576815472	[94]	[142,110,99,132]	2	hSpCas9	negative selection	5684199
14451088	14451111	19	+	27260156	A673	viability	TGCAAGCCCGCGCCGCTCACAGG	PKN1	ENSG00000123143	0.2382473692765601	[1015]	[1387,1413,1465,1481]	5	hSpCas9	negative selection	5748449
14450367	14450390	19	-	27260156	A673	viability	CCGCGTGCTCCACTCGGAAGTGG	PKN1	ENSG00000123143	-0.049611611472554024	[463]	[591,513,575,472]	-1	hSpCas9	negative selection	5748450
14451068	14451091	19	-	27260156	A673	viability	GCACAGGGTGCTGTAGTGCGTGG	PKN1	ENSG00000123143	0.07160176527949025	[183]	[240,216,247,222]	1	hSpCas9	negative selection	5748451
14450367	14450390	19	+	27260156	A375	viability	CCACTTCCGAGTGGAGCACGCGG	PKN1	ENSG00000123143	0.13725102850788257	[493]	[747,585,626,575]	2	hSpCas9	negative selection	5805448
14446487	14446510	19	+	27260156	A375	viability	TCATCCGCATGCAACTCCGCCGG	PKN1	ENSG00000123143	-0.32225321479023816	[1853]	[1730,1688,1724,1765]	-4	hSpCas9	negative selection	5805449
14446491	14446514	19	-	27260156	A375	viability	GCGCCCGGCGGAGTTGCATGCGG	PKN1	ENSG00000123143	0.325817302327589	[94]	[120,283,116,62]	5	hSpCas9	negative selection	5805450
14451088	14451111	19	+	27260156	A375	viability	TGCAAGCCCGCGCCGCTCACAGG	PKN1	ENSG00000123143	0.07640580448493495	[1015]	[1100,1289,1183,1409]	1	hSpCas9	negative selection	5869700
14450367	14450390	19	-	27260156	A375	viability	CCGCGTGCTCCACTCGGAAGTGG	PKN1	ENSG00000123143	-0.49321027449400573	[463]	[522,404,382,247]	-6	hSpCas9	negative selection	5869701
14451068	14451091	19	-	27260156	A375	viability	GCACAGGGTGCTGTAGTGCGTGG	PKN1	ENSG00000123143	0.246290127074704	[183]	[276,239,320,186]	3	hSpCas9	negative selection	5869702
14450367	14450390	19	+	27260156	COLO741	viability	CCACTTCCGAGTGGAGCACGCGG	PKN1	ENSG00000123143	0.1956065290807899	[493]	[806,659,707]	4	hSpCas9	negative selection	5926699
14446487	14446510	19	+	27260156	COLO741	viability	TCATCCGCATGCAACTCCGCCGG	PKN1	ENSG00000123143	-0.3349856242761218	[1853]	[2054,1871,1728]	-6	hSpCas9	negative selection	5926700
14446491	14446514	19	-	27260156	COLO741	viability	GCGCCCGGCGGAGTTGCATGCGG	PKN1	ENSG00000123143	0.40358392022540945	[94]	[155,178,146]	8	hSpCas9	negative selection	5926701
14451088	14451111	19	+	27260156	COLO741	viability	TGCAAGCCCGCGCCGCTCACAGG	PKN1	ENSG00000123143	0.28552323603623275	[1015]	[1840,1527,1408]	6	hSpCas9	negative selection	5990951
14450367	14450390	19	-	27260156	COLO741	viability	CCGCGTGCTCCACTCGGAAGTGG	PKN1	ENSG00000123143	-0.23619981992213254	[463]	[471,429,596]	-5	hSpCas9	negative selection	5990952
14451068	14451091	19	-	27260156	COLO741	viability	GCACAGGGTGCTGTAGTGCGTGG	PKN1	ENSG00000123143	0.04126265257873074	[183]	[203,288,229]	0	hSpCas9	negative selection	5990953
14450367	14450390	19	+	27260156	CAL120	viability	CCACTTCCGAGTGGAGCACGCGG	PKN1	ENSG00000123143	0.4595303310179013	[493]	[1261,531,804]	7	hSpCas9	negative selection	6047950
14446487	14446510	19	+	27260156	CAL120	viability	TCATCCGCATGCAACTCCGCCGG	PKN1	ENSG00000123143	-0.5762183506397691	[1853]	[1451,1837,1340]	-7	hSpCas9	negative selection	6047951
14446491	14446514	19	-	27260156	CAL120	viability	GCGCCCGGCGGAGTTGCATGCGG	PKN1	ENSG00000123143	0.950202406091071	[94]	[180,379,118]	9	hSpCas9	negative selection	6047952
14451088	14451111	19	+	27260156	CAL120	viability	TGCAAGCCCGCGCCGCTCACAGG	PKN1	ENSG00000123143	0.4194194373713511	[1015]	[1640,1655,1765]	6	hSpCas9	negative selection	6112202
14450367	14450390	19	-	27260156	CAL120	viability	CCGCGTGCTCCACTCGGAAGTGG	PKN1	ENSG00000123143	-0.24636548801961897	[463]	[490,331,634]	-4	hSpCas9	negative selection	6112203
14451068	14451091	19	-	27260156	CAL120	viability	GCACAGGGTGCTGTAGTGCGTGG	PKN1	ENSG00000123143	-0.2507724046920683	[183]	[107,234,220]	-4	hSpCas9	negative selection	6112204
14450367	14450390	19	+	27260156	CADOES1	viability	CCACTTCCGAGTGGAGCACGCGG	PKN1	ENSG00000123143	0.19329812416781683	[493]	[532,534,438,596]	3	hSpCas9	negative selection	6169201
14446487	14446510	19	+	27260156	CADOES1	viability	TCATCCGCATGCAACTCCGCCGG	PKN1	ENSG00000123143	-0.5107783013111016	[1853]	[1069,1251,1340,1176]	-7	hSpCas9	negative selection	6169202
14446491	14446514	19	-	27260156	CADOES1	viability	GCGCCCGGCGGAGTTGCATGCGG	PKN1	ENSG00000123143	0.0803733500278323	[94]	[48,165,63,94]	1	hSpCas9	negative selection	6169203
14451088	14451111	19	+	27260156	CADOES1	viability	TGCAAGCCCGCGCCGCTCACAGG	PKN1	ENSG00000123143	0.18293328139716603	[1015]	[1356,1174,871,878]	3	hSpCas9	negative selection	6233453
14450367	14450390	19	-	27260156	CADOES1	viability	CCGCGTGCTCCACTCGGAAGTGG	PKN1	ENSG00000123143	-0.39700689486505997	[463]	[304,309,391,302]	-6	hSpCas9	negative selection	6233454
14451068	14451091	19	-	27260156	CADOES1	viability	GCACAGGGTGCTGTAGTGCGTGG	PKN1	ENSG00000123143	0.009699154791191322	[183]	[192,161,188,143]	0	hSpCas9	negative selection	6233455
14450367	14450390	19	+	27260156	EWS502	viability	CCACTTCCGAGTGGAGCACGCGG	PKN1	ENSG00000123143	0.24113464172472554	[493]	[526,624,767,559]	4	hSpCas9	negative selection	6290452
14446487	14446510	19	+	27260156	EWS502	viability	TCATCCGCATGCAACTCCGCCGG	PKN1	ENSG00000123143	-0.2591558101146403	[1853]	[1471,1757,1887,1443]	-4	hSpCas9	negative selection	6290453
14446491	14446514	19	-	27260156	EWS502	viability	GCGCCCGGCGGAGTTGCATGCGG	PKN1	ENSG00000123143	0.6071095557200379	[94]	[138,185,111,176]	9	hSpCas9	negative selection	6290454
14451088	14451111	19	+	27260156	EWS502	viability	TGCAAGCCCGCGCCGCTCACAGG	PKN1	ENSG00000123143	0.26411123791878355	[1015]	[1071,1239,1725,1150]	4	hSpCas9	negative selection	6354704
14450367	14450390	19	-	27260156	EWS502	viability	CCGCGTGCTCCACTCGGAAGTGG	PKN1	ENSG00000123143	-0.18525587800646945	[463]	[488,519,362,336]	-3	hSpCas9	negative selection	6354705
14451068	14451091	19	-	27260156	EWS502	viability	GCACAGGGTGCTGTAGTGCGTGG	PKN1	ENSG00000123143	0.028685161484519828	[183]	[127,212,220,243]	0	hSpCas9	negative selection	6354706
14450367	14450390	19	+	27260156	EW8	viability	CCACTTCCGAGTGGAGCACGCGG	PKN1	ENSG00000123143	0.15132087690721074	[493]	[466,491,378,452]	2	hSpCas9	negative selection	6411703
14446487	14446510	19	+	27260156	EW8	viability	TCATCCGCATGCAACTCCGCCGG	PKN1	ENSG00000123143	-0.28099148317783684	[1853]	[1266,1430,1084,1189]	-5	hSpCas9	negative selection	6411704
14446491	14446514	19	-	27260156	EW8	viability	GCGCCCGGCGGAGTTGCATGCGG	PKN1	ENSG00000123143	0.2319903973319235	[94]	[101,159,43,64]	4	hSpCas9	negative selection	6411705
14451088	14451111	19	+	27260156	EW8	viability	TGCAAGCCCGCGCCGCTCACAGG	PKN1	ENSG00000123143	0.3708180172603055	[1015]	[1402,1019,905,990]	6	hSpCas9	negative selection	6475955
14450367	14450390	19	-	27260156	EW8	viability	CCGCGTGCTCCACTCGGAAGTGG	PKN1	ENSG00000123143	-0.21277914779979268	[463]	[329,350,244,384]	-4	hSpCas9	negative selection	6475956
14451068	14451091	19	-	27260156	EW8	viability	GCACAGGGTGCTGTAGTGCGTGG	PKN1	ENSG00000123143	-0.25250937359931647	[183]	[71,100,167,145]	-5	hSpCas9	negative selection	6475957
14450367	14450390	19	+	27260156	CORL105	viability	CCACTTCCGAGTGGAGCACGCGG	PKN1	ENSG00000123143	0.025455507124400326	[493]	[617,641,578,513]	0	hSpCas9	negative selection	6532954
14446487	14446510	19	+	27260156	CORL105	viability	TCATCCGCATGCAACTCCGCCGG	PKN1	ENSG00000123143	-0.6163460878109983	[1853]	[1535,1366,1270,1470]	-8	hSpCas9	negative selection	6532955
14446491	14446514	19	-	27260156	CORL105	viability	GCGCCCGGCGGAGTTGCATGCGG	PKN1	ENSG00000123143	-0.03626018075257198	[94]	[112,123,78,112]	0	hSpCas9	negative selection	6532956
14451088	14451111	19	+	27260156	CORL105	viability	TGCAAGCCCGCGCCGCTCACAGG	PKN1	ENSG00000123143	0.06020038829015051	[1015]	[1243,1264,1116,1313]	1	hSpCas9	negative selection	6597206
14450367	14450390	19	-	27260156	CORL105	viability	CCGCGTGCTCCACTCGGAAGTGG	PKN1	ENSG00000123143	-0.4666537531624831	[463]	[356,331,450,440]	-7	hSpCas9	negative selection	6597207
14451068	14451091	19	-	27260156	CORL105	viability	GCACAGGGTGCTGTAGTGCGTGG	PKN1	ENSG00000123143	-0.14680100506779548	[183]	[163,137,263,222]	-3	hSpCas9	negative selection	6597208
14450367	14450390	19	+	27260156	HS294T	viability	CCACTTCCGAGTGGAGCACGCGG	PKN1	ENSG00000123143	0.1927858419777692	[493]	[245,225,196,196]	2	hSpCas9	negative selection	6654205
14446487	14446510	19	+	27260156	HS294T	viability	TCATCCGCATGCAACTCCGCCGG	PKN1	ENSG00000123143	-0.2630842983461974	[1853]	[432,651,656,671]	-4	hSpCas9	negative selection	6654206
14446491	14446514	19	-	27260156	HS294T	viability	GCGCCCGGCGGAGTTGCATGCGG	PKN1	ENSG00000123143	0.4180155136313166	[94]	[33,51,34,81]	5	hSpCas9	negative selection	6654207
14451088	14451111	19	+	27260156	HS294T	viability	TGCAAGCCCGCGCCGCTCACAGG	PKN1	ENSG00000123143	0.4123810833787145	[1015]	[390,553,549,622]	5	hSpCas9	negative selection	6718457
14450367	14450390	19	-	27260156	HS294T	viability	CCGCGTGCTCCACTCGGAAGTGG	PKN1	ENSG00000123143	-0.17843011068413442	[463]	[156,85,210,186]	-3	hSpCas9	negative selection	6718458
14451068	14451091	19	-	27260156	HS294T	viability	GCACAGGGTGCTGTAGTGCGTGG	PKN1	ENSG00000123143	0.2173314118007985	[183]	[52,53,76,163]	3	hSpCas9	negative selection	6718459
14450367	14450390	19	+	27260156	HCC44	viability	CCACTTCCGAGTGGAGCACGCGG	PKN1	ENSG00000123143	0.10475984989266791	[493]	[624,463,877,503]	1	hSpCas9	negative selection	6775456
14446487	14446510	19	+	27260156	HCC44	viability	TCATCCGCATGCAACTCCGCCGG	PKN1	ENSG00000123143	-0.2908595301876127	[1853]	[1639,1398,2106,1798]	-4	hSpCas9	negative selection	6775457
14446491	14446514	19	-	27260156	HCC44	viability	GCGCCCGGCGGAGTTGCATGCGG	PKN1	ENSG00000123143	0.7095197068522816	[94]	[102,185,137,256]	9	hSpCas9	negative selection	6775458
14451088	14451111	19	+	27260156	HCC44	viability	TGCAAGCCCGCGCCGCTCACAGG	PKN1	ENSG00000123143	0.3468464951854695	[1015]	[1205,1332,1884,1476]	5	hSpCas9	negative selection	6839708
14450367	14450390	19	-	27260156	HCC44	viability	CCGCGTGCTCCACTCGGAAGTGG	PKN1	ENSG00000123143	-0.1031607143496806	[463]	[612,300,652,450]	-2	hSpCas9	negative selection	6839709
14451068	14451091	19	-	27260156	HCC44	viability	GCACAGGGTGCTGTAGTGCGTGG	PKN1	ENSG00000123143	0.3531569116299146	[183]	[137,305,413,212]	6	hSpCas9	negative selection	6839710
14450367	14450390	19	+	27260156	G402	viability	CCACTTCCGAGTGGAGCACGCGG	PKN1	ENSG00000123143	0.20528453522644247	[493]	[948,264,777,791]	2	hSpCas9	negative selection	6896707
14446487	14446510	19	+	27260156	G402	viability	TCATCCGCATGCAACTCCGCCGG	PKN1	ENSG00000123143	-0.15042748277913232	[1853]	[2378,1445,2256,2075]	-2	hSpCas9	negative selection	6896708
14446491	14446514	19	-	27260156	G402	viability	GCGCCCGGCGGAGTTGCATGCGG	PKN1	ENSG00000123143	0.20853273480632728	[94]	[123,74,82,242]	2	hSpCas9	negative selection	6896709
14451088	14451111	19	+	27260156	G402	viability	TGCAAGCCCGCGCCGCTCACAGG	PKN1	ENSG00000123143	0.2157283820890783	[1015]	[1709,2198,756,1182]	2	hSpCas9	negative selection	6960959
14450367	14450390	19	-	27260156	G402	viability	CCGCGTGCTCCACTCGGAAGTGG	PKN1	ENSG00000123143	-0.4616152901912806	[463]	[560,492,238,377]	-5	hSpCas9	negative selection	6960960
14451068	14451091	19	-	27260156	G402	viability	GCACAGGGTGCTGTAGTGCGTGG	PKN1	ENSG00000123143	-0.3978912190814574	[183]	[220,90,208,162]	-5	hSpCas9	negative selection	6960961
14450367	14450390	19	+	27260156	L33	viability	CCACTTCCGAGTGGAGCACGCGG	PKN1	ENSG00000123143	0.1281318273224341	[493]	[531,222,331,554]	3	hSpCas9	negative selection	7017958
14446487	14446510	19	+	27260156	L33	viability	TCATCCGCATGCAACTCCGCCGG	PKN1	ENSG00000123143	0.04541090855197938	[1853]	[1715,833,1270,1884]	1	hSpCas9	negative selection	7017959
14446491	14446514	19	-	27260156	L33	viability	GCGCCCGGCGGAGTTGCATGCGG	PKN1	ENSG00000123143	0.6655253957765217	[94]	[204,57,103,89]	9	hSpCas9	negative selection	7017960
14451088	14451111	19	+	27260156	L33	viability	TGCAAGCCCGCGCCGCTCACAGG	PKN1	ENSG00000123143	0.20902489162062654	[1015]	[1059,511,725,1234]	4	hSpCas9	negative selection	7082210
14450367	14450390	19	-	27260156	L33	viability	CCGCGTGCTCCACTCGGAAGTGG	PKN1	ENSG00000123143	0.0929041846502028	[463]	[472,237,352,365]	2	hSpCas9	negative selection	7082211
14451068	14451091	19	-	27260156	L33	viability	GCACAGGGTGCTGTAGTGCGTGG	PKN1	ENSG00000123143	0.09036125406072038	[183]	[228,66,137,170]	2	hSpCas9	negative selection	7082212
14450367	14450390	19	+	27260156	K562	viability	CCACTTCCGAGTGGAGCACGCGG	PKN1	ENSG00000123143	0.31985966347705985	[493]	[709,617,464,424]	4	hSpCas9	negative selection	7139209
14446487	14446510	19	+	27260156	K562	viability	TCATCCGCATGCAACTCCGCCGG	PKN1	ENSG00000123143	-0.11311812075673178	[1853]	[1688,1445,1175,1749]	-1	hSpCas9	negative selection	7139210
14446491	14446514	19	-	27260156	K562	viability	GCGCCCGGCGGAGTTGCATGCGG	PKN1	ENSG00000123143	-0.8962943202192482	[94]	[59,63,49,12]	-7	hSpCas9	negative selection	7139211
14451088	14451111	19	+	27260156	K562	viability	TGCAAGCCCGCGCCGCTCACAGG	PKN1	ENSG00000123143	0.4046715113352888	[1015]	[1189,1515,1623,533]	5	hSpCas9	negative selection	7203461
14450367	14450390	19	-	27260156	K562	viability	CCGCGTGCTCCACTCGGAAGTGG	PKN1	ENSG00000123143	0.2613658781682684	[463]	[992,279,312,423]	3	hSpCas9	negative selection	7203462
14451068	14451091	19	-	27260156	K562	viability	GCACAGGGTGCTGTAGTGCGTGG	PKN1	ENSG00000123143	-0.23511183739792463	[183]	[32,87,235,180]	-3	hSpCas9	negative selection	7203463
14450367	14450390	19	+	27260156	HT29	viability	CCACTTCCGAGTGGAGCACGCGG	PKN1	ENSG00000123143	0.28788727687035254	[493]	[652,788,832,659]	5	hSpCas9	negative selection	7260460
14446487	14446510	19	+	27260156	HT29	viability	TCATCCGCATGCAACTCCGCCGG	PKN1	ENSG00000123143	-0.30901190218940977	[1853]	[1730,1954,1902,1694]	-5	hSpCas9	negative selection	7260461
14446491	14446514	19	-	27260156	HT29	viability	GCGCCCGGCGGAGTTGCATGCGG	PKN1	ENSG00000123143	0.12241069021602113	[94]	[156,111,142,94]	2	hSpCas9	negative selection	7260462
14451088	14451111	19	+	27260156	HT29	viability	TGCAAGCCCGCGCCGCTCACAGG	PKN1	ENSG00000123143	0.12290952133336486	[1015]	[1497,1316,1280,1289]	2	hSpCas9	negative selection	7324712
14450367	14450390	19	-	27260156	HT29	viability	CCGCGTGCTCCACTCGGAAGTGG	PKN1	ENSG00000123143	-0.06951710477255756	[463]	[549,510,583,503]	-1	hSpCas9	negative selection	7324713
14451068	14451091	19	-	27260156	HT29	viability	GCACAGGGTGCTGTAGTGCGTGG	PKN1	ENSG00000123143	-0.334214569832578	[183]	[183,203,206,122]	-6	hSpCas9	negative selection	7324714
14450367	14450390	19	+	27260156	MHHES1	viability	CCACTTCCGAGTGGAGCACGCGG	PKN1	ENSG00000123143	0.1554587860590384	[493]	[580,683,566,630]	3	hSpCas9	negative selection	7381711
14446487	14446510	19	+	27260156	MHHES1	viability	TCATCCGCATGCAACTCCGCCGG	PKN1	ENSG00000123143	-0.12588277465886488	[1853]	[2492,1666,1803,1732]	-2	hSpCas9	negative selection	7381712
14446491	14446514	19	-	27260156	MHHES1	viability	GCGCCCGGCGGAGTTGCATGCGG	PKN1	ENSG00000123143	-0.1177568123754762	[94]	[83,80,90,125]	-2	hSpCas9	negative selection	7381713
14451088	14451111	19	+	27260156	MHHES1	viability	TGCAAGCCCGCGCCGCTCACAGG	PKN1	ENSG00000123143	-0.05869483287097288	[1015]	[1329,909,1228,945]	-1	hSpCas9	negative selection	7445963
14450367	14450390	19	-	27260156	MHHES1	viability	CCGCGTGCTCCACTCGGAAGTGG	PKN1	ENSG00000123143	-0.23662519911919092	[463]	[637,438,352,372]	-4	hSpCas9	negative selection	7445964
14451068	14451091	19	-	27260156	MHHES1	viability	GCACAGGGTGCTGTAGTGCGTGG	PKN1	ENSG00000123143	-0.3883339622896367	[183]	[194,191,212,60]	-6	hSpCas9	negative selection	7445965
14450367	14450390	19	+	27260156	MEWO	viability	CCACTTCCGAGTGGAGCACGCGG	PKN1	ENSG00000123143	0.2433933237886976	[493]	[633,550,472]	5	hSpCas9	negative selection	7502962
14446487	14446510	19	+	27260156	MEWO	viability	TCATCCGCATGCAACTCCGCCGG	PKN1	ENSG00000123143	-0.1572536985136408	[1853]	[1902,1394,1435]	-3	hSpCas9	negative selection	7502963
14446491	14446514	19	-	27260156	MEWO	viability	GCGCCCGGCGGAGTTGCATGCGG	PKN1	ENSG00000123143	0.1826654640493972	[94]	[112,90,100]	4	hSpCas9	negative selection	7502964
14451088	14451111	19	+	27260156	MEWO	viability	TGCAAGCCCGCGCCGCTCACAGG	PKN1	ENSG00000123143	0.12052603583560417	[1015]	[1284,946,916]	2	hSpCas9	negative selection	7567214
14450367	14450390	19	-	27260156	MEWO	viability	CCGCGTGCTCCACTCGGAAGTGG	PKN1	ENSG00000123143	0.1445170572307806	[463]	[675,358,442]	3	hSpCas9	negative selection	7567215
14451068	14451091	19	-	27260156	MEWO	viability	GCACAGGGTGCTGTAGTGCGTGG	PKN1	ENSG00000123143	-0.17274416150942162	[183]	[146,154,154]	-4	hSpCas9	negative selection	7567216
14450367	14450390	19	+	27260156	LNCAPCLONEFGC	viability	CCACTTCCGAGTGGAGCACGCGG	PKN1	ENSG00000123143	0.02172828698975686	[493]	[576,365,411,458]	0	hSpCas9	negative selection	7624213
14446487	14446510	19	+	27260156	LNCAPCLONEFGC	viability	TCATCCGCATGCAACTCCGCCGG	PKN1	ENSG00000123143	-0.4084300363263105	[1853]	[1122,1497,1298,1132]	-6	hSpCas9	negative selection	7624214
14446491	14446514	19	-	27260156	LNCAPCLONEFGC	viability	GCGCCCGGCGGAGTTGCATGCGG	PKN1	ENSG00000123143	0.448679717829257	[94]	[84,151,143,90]	7	hSpCas9	negative selection	7624215
14451088	14451111	19	+	27260156	LNCAPCLONEFGC	viability	TGCAAGCCCGCGCCGCTCACAGG	PKN1	ENSG00000123143	0.19107437326370458	[1015]	[1106,1022,1139,945]	3	hSpCas9	negative selection	7688465
14450367	14450390	19	-	27260156	LNCAPCLONEFGC	viability	CCGCGTGCTCCACTCGGAAGTGG	PKN1	ENSG00000123143	-0.696450996155736	[463]	[303,199,330,215]	-8	hSpCas9	negative selection	7688466
14451068	14451091	19	-	27260156	LNCAPCLONEFGC	viability	GCACAGGGTGCTGTAGTGCGTGG	PKN1	ENSG00000123143	0.47432809765028794	[183]	[175,142,500,152]	7	hSpCas9	negative selection	7688467
14450367	14450390	19	+	27260156	PANC0327	viability	CCACTTCCGAGTGGAGCACGCGG	PKN1	ENSG00000123143	0.6342088709495567	[493]	[1079,675,353,646]	8	hSpCas9	negative selection	7745464
14446487	14446510	19	+	27260156	PANC0327	viability	TCATCCGCATGCAACTCCGCCGG	PKN1	ENSG00000123143	-0.5657492915811819	[1853]	[988,1157,983,1302]	-7	hSpCas9	negative selection	7745465
14446491	14446514	19	-	27260156	PANC0327	viability	GCGCCCGGCGGAGTTGCATGCGG	PKN1	ENSG00000123143	-0.7754796659333878	[94]	[62,43,50,40]	-8	hSpCas9	negative selection	7745466
14451088	14451111	19	+	27260156	PANC0327	viability	TGCAAGCCCGCGCCGCTCACAGG	PKN1	ENSG00000123143	0.40215062444483096	[1015]	[922,692,1559,1636]	6	hSpCas9	negative selection	7809716
14450367	14450390	19	-	27260156	PANC0327	viability	CCGCGTGCTCCACTCGGAAGTGG	PKN1	ENSG00000123143	-0.09208114353248828	[463]	[313,281,355,601]	-1	hSpCas9	negative selection	7809717
14451068	14451091	19	-	27260156	PANC0327	viability	GCACAGGGTGCTGTAGTGCGTGG	PKN1	ENSG00000123143	0.13673268433089492	[183]	[174,120,229,199]	2	hSpCas9	negative selection	7809718
14450367	14450390	19	+	27260156	NCIH2009	viability	CCACTTCCGAGTGGAGCACGCGG	PKN1	ENSG00000123143	0.1497054964931579	[493]	[774,684,838]	2	hSpCas9	negative selection	7866715
14446487	14446510	19	+	27260156	NCIH2009	viability	TCATCCGCATGCAACTCCGCCGG	PKN1	ENSG00000123143	-0.061262824102160884	[1853]	[2917,2137,2479]	-1	hSpCas9	negative selection	7866716
14446491	14446514	19	-	27260156	NCIH2009	viability	GCGCCCGGCGGAGTTGCATGCGG	PKN1	ENSG00000123143	0.6107483613693814	[94]	[159,327,108]	8	hSpCas9	negative selection	7866717
14451088	14451111	19	+	27260156	NCIH2009	viability	TGCAAGCCCGCGCCGCTCACAGG	PKN1	ENSG00000123143	0.1548737997060139	[1015]	[1904,1613,1282]	2	hSpCas9	negative selection	7930967
14450367	14450390	19	-	27260156	NCIH2009	viability	CCGCGTGCTCCACTCGGAAGTGG	PKN1	ENSG00000123143	-0.24948706519061273	[463]	[646,388,621]	-3	hSpCas9	negative selection	7930968
14451068	14451091	19	-	27260156	NCIH2009	viability	GCACAGGGTGCTGTAGTGCGTGG	PKN1	ENSG00000123143	0.3132449488952207	[183]	[210,389,333]	4	hSpCas9	negative selection	7930969
14450367	14450390	19	+	27260156	NCIH1373	viability	CCACTTCCGAGTGGAGCACGCGG	PKN1	ENSG00000123143	0.661792858642755	[493]	[1248,774,830,184]	6	hSpCas9	negative selection	7987966
14446487	14446510	19	+	27260156	NCIH1373	viability	TCATCCGCATGCAACTCCGCCGG	PKN1	ENSG00000123143	0.1554933230300244	[1853]	[1800,2533,1718,827]	1	hSpCas9	negative selection	7987967
14446491	14446514	19	-	27260156	NCIH1373	viability	GCGCCCGGCGGAGTTGCATGCGG	PKN1	ENSG00000123143	0.7812146514916181	[94]	[145,407,48,24]	7	hSpCas9	negative selection	7987968
14451088	14451111	19	+	27260156	NCIH1373	viability	TGCAAGCCCGCGCCGCTCACAGG	PKN1	ENSG00000123143	0.4263085066436929	[1015]	[1419,1646,1311,451]	4	hSpCas9	negative selection	8052218
14450367	14450390	19	-	27260156	NCIH1373	viability	CCGCGTGCTCCACTCGGAAGTGG	PKN1	ENSG00000123143	-0.5939399600623215	[463]	[514,354,202,86]	-5	hSpCas9	negative selection	8052219
14451068	14451091	19	-	27260156	NCIH1373	viability	GCACAGGGTGCTGTAGTGCGTGG	PKN1	ENSG00000123143	-0.8113932436327902	[183]	[118,85,159,27]	-7	hSpCas9	negative selection	8052220
14450367	14450390	19	+	27260156	PATU8902	viability	CCACTTCCGAGTGGAGCACGCGG	PKN1	ENSG00000123143	0.275510825669572	[493]	[922,639,749,1057]	3	hSpCas9	negative selection	8109217
14446487	14446510	19	+	27260156	PATU8902	viability	TCATCCGCATGCAACTCCGCCGG	PKN1	ENSG00000123143	-0.3450897864350728	[1853]	[2588,1281,2284,1862]	-3	hSpCas9	negative selection	8109218
14446491	14446514	19	-	27260156	PATU8902	viability	GCGCCCGGCGGAGTTGCATGCGG	PKN1	ENSG00000123143	-0.24065293306961655	[94]	[109,41,170,107]	-2	hSpCas9	negative selection	8109219
14451088	14451111	19	+	27260156	PATU8902	viability	TGCAAGCCCGCGCCGCTCACAGG	PKN1	ENSG00000123143	0.23830736809617825	[1015]	[1453,2672,1081,1604]	2	hSpCas9	negative selection	8173469
14450367	14450390	19	-	27260156	PATU8902	viability	CCGCGTGCTCCACTCGGAAGTGG	PKN1	ENSG00000123143	-0.9232028445326552	[463]	[167,606,286,311]	-7	hSpCas9	negative selection	8173470
14451068	14451091	19	-	27260156	PATU8902	viability	GCACAGGGTGCTGTAGTGCGTGG	PKN1	ENSG00000123143	0.2991518273681306	[183]	[299,377,329,237]	3	hSpCas9	negative selection	8173471
14450367	14450390	19	+	27260156	PANC1	viability	CCACTTCCGAGTGGAGCACGCGG	PKN1	ENSG00000123143	-0.1602966632907392	[493]	[359,517,352,319]	-3	hSpCas9	negative selection	8230468
14446487	14446510	19	+	27260156	PANC1	viability	TCATCCGCATGCAACTCCGCCGG	PKN1	ENSG00000123143	-0.43201279531443304	[1853]	[1133,1652,1095,953]	-6	hSpCas9	negative selection	8230469
14446491	14446514	19	-	27260156	PANC1	viability	GCGCCCGGCGGAGTTGCATGCGG	PKN1	ENSG00000123143	0.219854088559563	[94]	[76,168,93,59]	3	hSpCas9	negative selection	8230470
14451088	14451111	19	+	27260156	PANC1	viability	TGCAAGCCCGCGCCGCTCACAGG	PKN1	ENSG00000123143	0.07595468748566847	[1015]	[876,900,829,1032]	1	hSpCas9	negative selection	8294720
14450367	14450390	19	-	27260156	PANC1	viability	CCGCGTGCTCCACTCGGAAGTGG	PKN1	ENSG00000123143	-0.34976003041450027	[463]	[229,304,341,360]	-5	hSpCas9	negative selection	8294721
14451068	14451091	19	-	27260156	PANC1	viability	GCACAGGGTGCTGTAGTGCGTGG	PKN1	ENSG00000123143	0.510839969788561	[183]	[169,239,308,188]	8	hSpCas9	negative selection	8294722
14450367	14450390	19	+	27260156	PANC0813	viability	CCACTTCCGAGTGGAGCACGCGG	PKN1	ENSG00000123143	0.3261455229172287	[493]	[645,968,743,551]	5	hSpCas9	negative selection	8351719
14446487	14446510	19	+	27260156	PANC0813	viability	TCATCCGCATGCAACTCCGCCGG	PKN1	ENSG00000123143	0.07267568345268582	[1853]	[1987,2065,2461,2596]	1	hSpCas9	negative selection	8351720
14446491	14446514	19	-	27260156	PANC0813	viability	GCGCCCGGCGGAGTTGCATGCGG	PKN1	ENSG00000123143	0.9489689779471528	[94]	[148,217,281,206]	9	hSpCas9	negative selection	8351721
14451088	14451111	19	+	27260156	PANC0813	viability	TGCAAGCCCGCGCCGCTCACAGG	PKN1	ENSG00000123143	0.09263223229010564	[1015]	[1284,1528,1037,1237]	1	hSpCas9	negative selection	8415971
14450367	14450390	19	-	27260156	PANC0813	viability	CCGCGTGCTCCACTCGGAAGTGG	PKN1	ENSG00000123143	0.11645287055472145	[463]	[719,658,567,435]	2	hSpCas9	negative selection	8415972
14451068	14451091	19	-	27260156	PANC0813	viability	GCACAGGGTGCTGTAGTGCGTGG	PKN1	ENSG00000123143	0.2935570426361165	[183]	[355,226,160,319]	5	hSpCas9	negative selection	8415973
14450367	14450390	19	+	27260156	RDES	viability	CCACTTCCGAGTGGAGCACGCGG	PKN1	ENSG00000123143	0.11643522101129215	[493]	[540,645,589,689]	2	hSpCas9	negative selection	8472970
14446487	14446510	19	+	27260156	RDES	viability	TCATCCGCATGCAACTCCGCCGG	PKN1	ENSG00000123143	-0.30153639192725046	[1853]	[1405,1558,2097,1936]	-5	hSpCas9	negative selection	8472971
14446491	14446514	19	-	27260156	RDES	viability	GCGCCCGGCGGAGTTGCATGCGG	PKN1	ENSG00000123143	0.12012369995325445	[94]	[77,163,97,137]	2	hSpCas9	negative selection	8472972
14451088	14451111	19	+	27260156	RDES	viability	TGCAAGCCCGCGCCGCTCACAGG	PKN1	ENSG00000123143	0.15782562605356976	[1015]	[1048,1201,1410,1631]	2	hSpCas9	negative selection	8537222
14450367	14450390	19	-	27260156	RDES	viability	CCGCGTGCTCCACTCGGAAGTGG	PKN1	ENSG00000123143	-0.40681181611494815	[463]	[300,410,385,541]	-6	hSpCas9	negative selection	8537223
14451068	14451091	19	-	27260156	RDES	viability	GCACAGGGTGCTGTAGTGCGTGG	PKN1	ENSG00000123143	0.20821783724537868	[183]	[235,214,211,321]	3	hSpCas9	negative selection	8537224
14450367	14450390	19	+	27260156	PC3	viability	CCACTTCCGAGTGGAGCACGCGG	PKN1	ENSG00000123143	-0.016750466943097217	[493]	[313,442,694,610]	0	hSpCas9	negative selection	8594221
14446487	14446510	19	+	27260156	PC3	viability	TCATCCGCATGCAACTCCGCCGG	PKN1	ENSG00000123143	-0.5419756619139413	[1853]	[721,1364,2202,1270]	-8	hSpCas9	negative selection	8594222
14446491	14446514	19	-	27260156	PC3	viability	GCGCCCGGCGGAGTTGCATGCGG	PKN1	ENSG00000123143	-0.24123830854273542	[94]	[90,56,92,66]	-5	hSpCas9	negative selection	8594223
14451088	14451111	19	+	27260156	PC3	viability	TGCAAGCCCGCGCCGCTCACAGG	PKN1	ENSG00000123143	0.14498147637406467	[1015]	[729,917,2008,1244]	3	hSpCas9	negative selection	8658473
14450367	14450390	19	-	27260156	PC3	viability	CCGCGTGCTCCACTCGGAAGTGG	PKN1	ENSG00000123143	-0.4621351859277327	[463]	[274,293,571,278]	-8	hSpCas9	negative selection	8658474
14451068	14451091	19	-	27260156	PC3	viability	GCACAGGGTGCTGTAGTGCGTGG	PKN1	ENSG00000123143	0.3657673887848003	[183]	[138,274,541,121]	7	hSpCas9	negative selection	8658475
14450367	14450390	19	+	27260156	PATU8988T	viability	CCACTTCCGAGTGGAGCACGCGG	PKN1	ENSG00000123143	0.0487282715290846	[493]	[351,493,681,439]	0	hSpCas9	negative selection	8715472
14446487	14446510	19	+	27260156	PATU8988T	viability	TCATCCGCATGCAACTCCGCCGG	PKN1	ENSG00000123143	-0.3258462666999502	[1853]	[1311,1389,1523,1490]	-5	hSpCas9	negative selection	8715473
14446491	14446514	19	-	27260156	PATU8988T	viability	GCGCCCGGCGGAGTTGCATGCGG	PKN1	ENSG00000123143	-0.3538896494073951	[94]	[24,150,37,81]	-5	hSpCas9	negative selection	8715474
14451088	14451111	19	+	27260156	PATU8988T	viability	TGCAAGCCCGCGCCGCTCACAGG	PKN1	ENSG00000123143	0.6070423701502929	[1015]	[2940,996,721,1266]	8	hSpCas9	negative selection	8779724
14450367	14450390	19	-	27260156	PATU8988T	viability	CCGCGTGCTCCACTCGGAAGTGG	PKN1	ENSG00000123143	-0.0915415794904183	[463]	[378,440,430,434]	-1	hSpCas9	negative selection	8779725
14451068	14451091	19	-	27260156	PATU8988T	viability	GCACAGGGTGCTGTAGTGCGTGG	PKN1	ENSG00000123143	0.12125382920968564	[183]	[304,193,122,148]	2	hSpCas9	negative selection	8779726
14450367	14450390	19	+	27260156	T47D	viability	CCACTTCCGAGTGGAGCACGCGG	PKN1	ENSG00000123143	0.2012625531375929	[493]	[684,538,657,778]	4	hSpCas9	negative selection	8836723
14446487	14446510	19	+	27260156	T47D	viability	TCATCCGCATGCAACTCCGCCGG	PKN1	ENSG00000123143	-0.29250185915582794	[1853]	[1918,1695,1626,1821]	-6	hSpCas9	negative selection	8836724
14446491	14446514	19	-	27260156	T47D	viability	GCGCCCGGCGGAGTTGCATGCGG	PKN1	ENSG00000123143	0.1683412208575512	[94]	[159,101,66,172]	3	hSpCas9	negative selection	8836725
14451088	14451111	19	+	27260156	T47D	viability	TGCAAGCCCGCGCCGCTCACAGG	PKN1	ENSG00000123143	0.18558570197649726	[1015]	[1373,1336,1148,1533]	4	hSpCas9	negative selection	8900975
14450367	14450390	19	-	27260156	T47D	viability	CCGCGTGCTCCACTCGGAAGTGG	PKN1	ENSG00000123143	-0.04758080785232564	[463]	[418,467,555,656]	-1	hSpCas9	negative selection	8900976
14451068	14451091	19	-	27260156	T47D	viability	GCACAGGGTGCTGTAGTGCGTGG	PKN1	ENSG00000123143	0.08851085744872744	[183]	[198,235,256,217]	1	hSpCas9	negative selection	8900977
14450367	14450390	19	+	27260156	SU8686	viability	CCACTTCCGAGTGGAGCACGCGG	PKN1	ENSG00000123143	0.10058280984679861	[493]	[522,330,583,716]	1	hSpCas9	negative selection	8957974
14446487	14446510	19	+	27260156	SU8686	viability	TCATCCGCATGCAACTCCGCCGG	PKN1	ENSG00000123143	-0.14109191175024138	[1853]	[1379,1451,1968,1972]	-2	hSpCas9	negative selection	8957975
14446491	14446514	19	-	27260156	SU8686	viability	GCGCCCGGCGGAGTTGCATGCGG	PKN1	ENSG00000123143	0.7141671712383932	[94]	[88,138,90,334]	9	hSpCas9	negative selection	8957976
14451088	14451111	19	+	27260156	SU8686	viability	TGCAAGCCCGCGCCGCTCACAGG	PKN1	ENSG00000123143	0.14990203704529814	[1015]	[1032,1033,1008,1458]	2	hSpCas9	negative selection	9022226
14450367	14450390	19	-	27260156	SU8686	viability	CCGCGTGCTCCACTCGGAAGTGG	PKN1	ENSG00000123143	-0.3414715855246803	[463]	[370,261,373,472]	-5	hSpCas9	negative selection	9022227
14451068	14451091	19	-	27260156	SU8686	viability	GCACAGGGTGCTGTAGTGCGTGG	PKN1	ENSG00000123143	-0.3598325512703997	[183]	[119,97,229,127]	-5	hSpCas9	negative selection	9022228
14450367	14450390	19	+	27260156	SKES1	viability	CCACTTCCGAGTGGAGCACGCGG	PKN1	ENSG00000123143	0.0650702471797499	[493]	[768,710,285,369]	1	hSpCas9	negative selection	9079225
14446487	14446510	19	+	27260156	SKES1	viability	TCATCCGCATGCAACTCCGCCGG	PKN1	ENSG00000123143	-0.46079256642511934	[1853]	[1435,1434,1277,1247]	-7	hSpCas9	negative selection	9079226
14446491	14446514	19	-	27260156	SKES1	viability	GCGCCCGGCGGAGTTGCATGCGG	PKN1	ENSG00000123143	0.0023747658489075008	[94]	[55,87,60,159]	0	hSpCas9	negative selection	9079227
14451088	14451111	19	+	27260156	SKES1	viability	TGCAAGCCCGCGCCGCTCACAGG	PKN1	ENSG00000123143	-0.08503485872084138	[1015]	[1023,1207,901,743]	-2	hSpCas9	negative selection	9143477
14450367	14450390	19	-	27260156	SKES1	viability	CCGCGTGCTCCACTCGGAAGTGG	PKN1	ENSG00000123143	-0.16659432596463794	[463]	[410,476,399,369]	-4	hSpCas9	negative selection	9143478
14451068	14451091	19	-	27260156	SKES1	viability	GCACAGGGTGCTGTAGTGCGTGG	PKN1	ENSG00000123143	-0.06784507542298912	[183]	[295,111,151,150]	-1	hSpCas9	negative selection	9143479
14450367	14450390	19	+	27260156	TOV112D	viability	CCACTTCCGAGTGGAGCACGCGG	PKN1	ENSG00000123143	0.24747573209307838	[493]	[682,583,694,398]	5	hSpCas9	negative selection	9200476
14446487	14446510	19	+	27260156	TOV112D	viability	TCATCCGCATGCAACTCCGCCGG	PKN1	ENSG00000123143	-0.2607592890286181	[1853]	[1646,1796,1315,1506]	-5	hSpCas9	negative selection	9200477
14446491	14446514	19	-	27260156	TOV112D	viability	GCGCCCGGCGGAGTTGCATGCGG	PKN1	ENSG00000123143	0.6928286533200045	[94]	[115,56,81,327]	9	hSpCas9	negative selection	9200478
14451088	14451111	19	+	27260156	TOV112D	viability	TGCAAGCCCGCGCCGCTCACAGG	PKN1	ENSG00000123143	0.1741022976033837	[1015]	[1186,1477,1081,933]	3	hSpCas9	negative selection	9264728
14450367	14450390	19	-	27260156	TOV112D	viability	CCGCGTGCTCCACTCGGAAGTGG	PKN1	ENSG00000123143	-0.3607473247443615	[463]	[471,341,369,269]	-6	hSpCas9	negative selection	9264729
14451068	14451091	19	-	27260156	TOV112D	viability	GCACAGGGTGCTGTAGTGCGTGG	PKN1	ENSG00000123143	0.19640877672113177	[183]	[94,102,474,136]	4	hSpCas9	negative selection	9264730
14450367	14450390	19	+	27260156	TC71	viability	CCACTTCCGAGTGGAGCACGCGG	PKN1	ENSG00000123143	0.12089551243639905	[493]	[627,557,463,660]	3	hSpCas9	negative selection	9321727
14446487	14446510	19	+	27260156	TC71	viability	TCATCCGCATGCAACTCCGCCGG	PKN1	ENSG00000123143	-0.3507428877211842	[1853]	[1491,1474,1658,1608]	-7	hSpCas9	negative selection	9321728
14446491	14446514	19	-	27260156	TC71	viability	GCGCCCGGCGGAGTTGCATGCGG	PKN1	ENSG00000123143	0.33680774953907533	[94]	[105,114,151,141]	7	hSpCas9	negative selection	9321729
14451088	14451111	19	+	27260156	TC71	viability	TGCAAGCCCGCGCCGCTCACAGG	PKN1	ENSG00000123143	-0.03373484231393875	[1015]	[1114,1096,952,1094]	-1	hSpCas9	negative selection	9385979
14450367	14450390	19	-	27260156	TC71	viability	CCGCGTGCTCCACTCGGAAGTGG	PKN1	ENSG00000123143	0.025773420218118244	[463]	[359,640,541,482]	0	hSpCas9	negative selection	9385980
14451068	14451091	19	-	27260156	TC71	viability	GCACAGGGTGCTGTAGTGCGTGG	PKN1	ENSG00000123143	-0.13451032937487128	[183]	[224,121,173,197]	-4	hSpCas9	negative selection	9385981
14450367	14450390	19	+	27260156	TC32	viability	CCACTTCCGAGTGGAGCACGCGG	PKN1	ENSG00000123143	0.3040646824291025	[493]	[601,403,698,638]	5	hSpCas9	negative selection	9442978
14446487	14446510	19	+	27260156	TC32	viability	TCATCCGCATGCAACTCCGCCGG	PKN1	ENSG00000123143	-0.18976330523042284	[1853]	[1391,972,2108,1898]	-3	hSpCas9	negative selection	9442979
14446491	14446514	19	-	27260156	TC32	viability	GCGCCCGGCGGAGTTGCATGCGG	PKN1	ENSG00000123143	-0.0003809483613790299	[94]	[111,48,84,118]	0	hSpCas9	negative selection	9442980
14451088	14451111	19	+	27260156	TC32	viability	TGCAAGCCCGCGCCGCTCACAGG	PKN1	ENSG00000123143	0.10653869167107577	[1015]	[970,529,1447,1396]	2	hSpCas9	negative selection	9507230
14450367	14450390	19	-	27260156	TC32	viability	CCGCGTGCTCCACTCGGAAGTGG	PKN1	ENSG00000123143	-0.14961908478702868	[463]	[317,386,480,387]	-3	hSpCas9	negative selection	9507231
14451068	14451091	19	-	27260156	TC32	viability	GCACAGGGTGCTGTAGTGCGTGG	PKN1	ENSG00000123143	0.21555576470363258	[183]	[199,147,330,151]	4	hSpCas9	negative selection	9507232
14441244	14441267	19	+	27869803	HPAFII	viability after 27 days	GCTGCGGCGGGAAATCCGCAAGG	PKN1	ENSG00000123143	0.5274932965628312	[127]	[66,121,NaN]	4	hSpCas9	negative selection	9565944
14443589	14443612	19	+	27869803	HPAFII	viability after 27 days	ATGATCCAGACCTACAGCAATGG	PKN1	ENSG00000123143	-0.060254516554717474	[568]	[365,220,NaN]	0	hSpCas9	negative selection	9565946
14446488	14446511	19	+	27869803	HPAFII	viability after 27 days	CATCCGCATGCAACTCCGCCGGG	PKN1	ENSG00000123143	-0.188207588218523	[210]	[116,80,NaN]	-1	hSpCas9	negative selection	9565948
14450370	14450393	19	+	27869803	HPAFII	viability after 27 days	CTTCCGAGTGGAGCACGCGGTGG	PKN1	ENSG00000123143	-1.6432724469300166	[295]	[69,32,NaN]	-8	hSpCas9	negative selection	9565949
14451058	14451081	19	-	27869803	HPAFII	viability after 27 days	CTGTAGTGCGTGGCGGGAAAGGG	PKN1	ENSG00000123143	0.9639134438384751	[662]	[536,798,NaN]	7	hSpCas9	negative selection	9565950
14451862	14451885	19	+	27869803	HPAFII	viability after 27 days	ACCTCCCAGAGACCATCCCGTGG	PKN1	ENSG00000123143	-0.33837143484038484	[377]	[208,113,NaN]	-3	hSpCas9	negative selection	9565951
14441244	14441267	19	+	27869803	HPAFII	viability after 15 days	GCTGCGGCGGGAAATCCGCAAGG	PKN1	ENSG00000123143	0.09810626385561838	[127]	[100,175,NaN]	1	hSpCas9	negative selection	9648393
14443589	14443612	19	+	27869803	HPAFII	viability after 15 days	ATGATCCAGACCTACAGCAATGG	PKN1	ENSG00000123143	-0.19951610683643828	[568]	[764,387,NaN]	-2	hSpCas9	negative selection	9648395
14446488	14446511	19	+	27869803	HPAFII	viability after 15 days	CATCCGCATGCAACTCCGCCGGG	PKN1	ENSG00000123143	-1.1276023898868899	[210]	[133,84,NaN]	-8	hSpCas9	negative selection	9648397
14450370	14450393	19	+	27869803	HPAFII	viability after 15 days	CTTCCGAGTGGAGCACGCGGTGG	PKN1	ENSG00000123143	-1.0694126796662342	[295]	[203,118,NaN]	-8	hSpCas9	negative selection	9648398
14451058	14451081	19	-	27869803	HPAFII	viability after 15 days	CTGTAGTGCGTGGCGGGAAAGGG	PKN1	ENSG00000123143	0.5112656958655362	[662]	[1104,959,NaN]	6	hSpCas9	negative selection	9648399
14451862	14451885	19	+	27869803	HPAFII	viability after 15 days	ACCTCCCAGAGACCATCCCGTGG	PKN1	ENSG00000123143	-0.3577972721532295	[377]	[501,201,NaN]	-4	hSpCas9	negative selection	9648400
14441244	14441267	19	+	27869803	ASPC1	viability after 36 days	GCTGCGGCGGGAAATCCGCAAGG	PKN1	ENSG00000123143	-1.0519283570733564	[322]	[114,55,9]	-7	hSpCas9	negative selection	9730842
14443589	14443612	19	+	27869803	ASPC1	viability after 36 days	ATGATCCAGACCTACAGCAATGG	PKN1	ENSG00000123143	-0.2879306959568587	[1158]	[497,183,327]	-3	hSpCas9	negative selection	9730844
14446488	14446511	19	+	27869803	ASPC1	viability after 36 days	CATCCGCATGCAACTCCGCCGGG	PKN1	ENSG00000123143	1.0248035943287788	[318]	[100,561,45]	8	hSpCas9	negative selection	9730846
14450370	14450393	19	+	27869803	ASPC1	viability after 36 days	CTTCCGAGTGGAGCACGCGGTGG	PKN1	ENSG00000123143	0.7720433738316498	[700]	[254,899,144]	7	hSpCas9	negative selection	9730847
14451058	14451081	19	-	27869803	ASPC1	viability after 36 days	CTGTAGTGCGTGGCGGGAAAGGG	PKN1	ENSG00000123143	0.33404022723850724	[1762]	[1310,562,560]	3	hSpCas9	negative selection	9730848
14451862	14451885	19	+	27869803	ASPC1	viability after 36 days	ACCTCCCAGAGACCATCCCGTGG	PKN1	ENSG00000123143	0.3226509432678589	[856]	[101,663,330]	3	hSpCas9	negative selection	9730849
14441244	14441267	19	+	27869803	PATU8988S	viability after 35 days	GCTGCGGCGGGAAATCCGCAAGG	PKN1	ENSG00000123143	0.5337352449417846	[317]	[145,224,NaN]	6	hSpCas9	negative selection	9813291
14443589	14443612	19	+	27869803	PATU8988S	viability after 35 days	ATGATCCAGACCTACAGCAATGG	PKN1	ENSG00000123143	-0.010524060484379039	[897]	[376,340,NaN]	0	hSpCas9	negative selection	9813293
14446488	14446511	19	+	27869803	PATU8988S	viability after 35 days	CATCCGCATGCAACTCCGCCGGG	PKN1	ENSG00000123143	1.6627966205403883	[284]	[336,389,NaN]	9	hSpCas9	negative selection	9813295
14450370	14450393	19	+	27869803	PATU8988S	viability after 35 days	CTTCCGAGTGGAGCACGCGGTGG	PKN1	ENSG00000123143	-1.7801989247199546	[652]	[106,45,NaN]	-8	hSpCas9	negative selection	9813296
14451058	14451081	19	-	27869803	PATU8988S	viability after 35 days	CTGTAGTGCGTGGCGGGAAAGGG	PKN1	ENSG00000123143	0.35669172270220173	[1251]	[503,787,NaN]	4	hSpCas9	negative selection	9813297
14451862	14451885	19	+	27869803	PATU8988S	viability after 35 days	ACCTCCCAGAGACCATCCCGTGG	PKN1	ENSG00000123143	-0.36579338223034064	[866]	[262,278,NaN]	-4	hSpCas9	negative selection	9813298
14441244	14441267	19	+	27869803	PATU8988S	viability after 31 days	GCTGCGGCGGGAAATCCGCAAGG	PKN1	ENSG00000123143	-0.14897018348051272	[317]	[116,110,NaN]	-2	hSpCas9	negative selection	9895740
14443589	14443612	19	+	27869803	PATU8988S	viability after 31 days	ATGATCCAGACCTACAGCAATGG	PKN1	ENSG00000123143	0.013498509187777952	[897]	[349,375,NaN]	0	hSpCas9	negative selection	9895742
14446488	14446511	19	+	27869803	PATU8988S	viability after 31 days	CATCCGCATGCAACTCCGCCGGG	PKN1	ENSG00000123143	1.4215660531160794	[284]	[204,430,NaN]	9	hSpCas9	negative selection	9895744
14450370	14450393	19	+	27869803	PATU8988S	viability after 31 days	CTTCCGAGTGGAGCACGCGGTGG	PKN1	ENSG00000123143	-1.538921029662815	[652]	[126,41,NaN]	-8	hSpCas9	negative selection	9895745
14451058	14451081	19	-	27869803	PATU8988S	viability after 31 days	CTGTAGTGCGTGGCGGGAAAGGG	PKN1	ENSG00000123143	0.28639755411082346	[1251]	[475,777,NaN]	3	hSpCas9	negative selection	9895746
14451862	14451885	19	+	27869803	PATU8988S	viability after 31 days	ACCTCCCAGAGACCATCCCGTGG	PKN1	ENSG00000123143	0.050668900566284925	[866]	[299,431,NaN]	0	hSpCas9	negative selection	9895747
14441244	14441267	19	+	27869803	HPAFII	viability after 35 days	GCTGCGGCGGGAAATCCGCAAGG	PKN1	ENSG00000123143	1.1969643616872814	[127]	[85,218,NaN]	7	hSpCas9	negative selection	9978189
14443589	14443612	19	+	27869803	HPAFII	viability after 35 days	ATGATCCAGACCTACAGCAATGG	PKN1	ENSG00000123143	0.1969896590459379	[568]	[372,281,NaN]	1	hSpCas9	negative selection	9978191
14446488	14446511	19	+	27869803	HPAFII	viability after 35 days	CATCCGCATGCAACTCCGCCGGG	PKN1	ENSG00000123143	-0.06518833501405782	[210]	[63,144,NaN]	0	hSpCas9	negative selection	9978193
14450370	14450393	19	+	27869803	HPAFII	viability after 35 days	CTTCCGAGTGGAGCACGCGGTGG	PKN1	ENSG00000123143	-0.6955827019412812	[295]	[84,100,NaN]	-4	hSpCas9	negative selection	9978194
14451058	14451081	19	-	27869803	HPAFII	viability after 35 days	CTGTAGTGCGTGGCGGGAAAGGG	PKN1	ENSG00000123143	0.9286010961122089	[662]	[374,935,NaN]	6	hSpCas9	negative selection	9978195
14451862	14451885	19	+	27869803	HPAFII	viability after 35 days	ACCTCCCAGAGACCATCCCGTGG	PKN1	ENSG00000123143	-0.6860550708912941	[377]	[117,119,NaN]	-4	hSpCas9	negative selection	9978196
14441244	14441267	19	+	27869803	HPAFII	viability after 31 days	GCTGCGGCGGGAAATCCGCAAGG	PKN1	ENSG00000123143	0.8036825584984086	[127]	[55,200,NaN]	6	hSpCas9	negative selection	10060638
14443589	14443612	19	+	27869803	HPAFII	viability after 31 days	ATGATCCAGACCTACAGCAATGG	PKN1	ENSG00000123143	0.463382581825857	[568]	[401,481,NaN]	3	hSpCas9	negative selection	10060640
14446488	14446511	19	+	27869803	HPAFII	viability after 31 days	CATCCGCATGCAACTCCGCCGGG	PKN1	ENSG00000123143	-0.25743485801979604	[210]	[133,60,NaN]	-2	hSpCas9	negative selection	10060642
14450370	14450393	19	+	27869803	HPAFII	viability after 31 days	CTTCCGAGTGGAGCACGCGGTGG	PKN1	ENSG00000123143	-1.437426706462595	[295]	[79,40,NaN]	-7	hSpCas9	negative selection	10060643
14451058	14451081	19	-	27869803	HPAFII	viability after 31 days	CTGTAGTGCGTGGCGGGAAAGGG	PKN1	ENSG00000123143	0.7401830422738294	[662]	[476,778,NaN]	5	hSpCas9	negative selection	10060644
14451862	14451885	19	+	27869803	HPAFII	viability after 31 days	ACCTCCCAGAGACCATCCCGTGG	PKN1	ENSG00000123143	-0.08084754918516579	[377]	[179,222,NaN]	0	hSpCas9	negative selection	10060645
14441282	14441305	19	+	28162770	P31FUJ	viability	AGGGTGCTGAGAACCTGCGGCGG	PKN1	ENSG00000123143	0.2567135108237417	[150]	[211]	2	hSpCas9	negative selection	10211951
14446540	14446563	19	+	28162770	P31FUJ	viability	GCAGCCCCGGATGACACCCAAGG	PKN1	ENSG00000123143	0.19346255028771941	[127]	[171]	2	hSpCas9	negative selection	10211952
14451000	14451023	19	+	28162770	P31FUJ	viability	GCTGCGAGAAGAGCTCGCTGCGG	PKN1	ENSG00000123143	-1.4551946257508266	[160]	[68]	-7	hSpCas9	negative selection	10211953
14451026	14451049	19	-	28162770	P31FUJ	viability	GCGGGTGCTGAAGGCAGCGGAGG	PKN1	ENSG00000123143	-1.4818297522542931	[163]	[68]	-7	hSpCas9	negative selection	10211954
14441205	14441228	19	-	28162770	P31FUJ	viability	CCAGCTGCTGCTGTACCCCGGGG	PKN1	ENSG00000123143	0.33968478275971714	[270]	[402]	4	hSpCas9	negative selection	10211955
14441244	14441267	19	+	28162770	P31FUJ	viability	GCTGCGGCGGGAAATCCGCAAGG	PKN1	ENSG00000123143	0.5609059015379261	[348]	[604]	6	hSpCas9	negative selection	10211956
14441262	14441285	19	+	28162770	P31FUJ	viability	CAAGGAGCTGAAGCTGAAGGAGG	PKN1	ENSG00000123143	-0.044685205295681096	[358]	[408]	0	hSpCas9	negative selection	10211957
14441306	14441329	19	-	28162770	P31FUJ	viability	GCTGCGGCCCAGGTCAGTGGTGG	PKN1	ENSG00000123143	0.855145494861324	[174]	[371]	8	hSpCas9	negative selection	10211958
14441367	14441390	19	-	28162770	P31FUJ	viability	GCTGGTGCAGCAGGTCGAGGCGG	PKN1	ENSG00000123143	0.1344067697738502	[206]	[266]	1	hSpCas9	negative selection	10211959
14441408	14441431	19	-	28162770	P31FUJ	viability	CGGGTCGGGAAGCACCACGTGGG	PKN1	ENSG00000123143	0.3239266155778336	[171]	[252]	3	hSpCas9	negative selection	10211960
14441282	14441305	19	+	28162770	TF1	viability	AGGGTGCTGAGAACCTGCGGCGG	PKN1	ENSG00000123143	NaN	[NaN]	[73]	1	hSpCas9	negative selection	10381317
14446540	14446563	19	+	28162770	TF1	viability	GCAGCCCCGGATGACACCCAAGG	PKN1	ENSG00000123143	NaN	[NaN]	[127]	1	hSpCas9	negative selection	10381318
14451000	14451023	19	+	28162770	TF1	viability	GCTGCGAGAAGAGCTCGCTGCGG	PKN1	ENSG00000123143	NaN	[NaN]	[91]	1	hSpCas9	negative selection	10381319
14451026	14451049	19	-	28162770	TF1	viability	GCGGGTGCTGAAGGCAGCGGAGG	PKN1	ENSG00000123143	NaN	[NaN]	[10]	1	hSpCas9	negative selection	10381320
14441205	14441228	19	-	28162770	TF1	viability	CCAGCTGCTGCTGTACCCCGGGG	PKN1	ENSG00000123143	NaN	[NaN]	[160]	1	hSpCas9	negative selection	10381321
14441244	14441267	19	+	28162770	TF1	viability	GCTGCGGCGGGAAATCCGCAAGG	PKN1	ENSG00000123143	NaN	[NaN]	[410]	1	hSpCas9	negative selection	10381322
14441262	14441285	19	+	28162770	TF1	viability	CAAGGAGCTGAAGCTGAAGGAGG	PKN1	ENSG00000123143	NaN	[NaN]	[332]	1	hSpCas9	negative selection	10381323
14441306	14441329	19	-	28162770	TF1	viability	GCTGCGGCCCAGGTCAGTGGTGG	PKN1	ENSG00000123143	NaN	[NaN]	[131]	1	hSpCas9	negative selection	10381324
14441367	14441390	19	-	28162770	TF1	viability	GCTGGTGCAGCAGGTCGAGGCGG	PKN1	ENSG00000123143	NaN	[NaN]	[290]	1	hSpCas9	negative selection	10381325
14441408	14441431	19	-	28162770	TF1	viability	CGGGTCGGGAAGCACCACGTGGG	PKN1	ENSG00000123143	NaN	[NaN]	[143]	1	hSpCas9	negative selection	10381326
14441282	14441305	19	+	28162770	SKM1	viability	AGGGTGCTGAGAACCTGCGGCGG	PKN1	ENSG00000123143	0.2399260511211964	[56]	[118]	2	hSpCas9	negative selection	10550683
14446540	14446563	19	+	28162770	SKM1	viability	GCAGCCCCGGATGACACCCAAGG	PKN1	ENSG00000123143	0.10399772053421774	[29]	[56]	1	hSpCas9	negative selection	10550684
14451000	14451023	19	+	28162770	SKM1	viability	GCTGCGAGAAGAGCTCGCTGCGG	PKN1	ENSG00000123143	-0.7000111736433949	[33]	[36]	-5	hSpCas9	negative selection	10550685
14451026	14451049	19	-	28162770	SKM1	viability	GCGGGTGCTGAAGGCAGCGGAGG	PKN1	ENSG00000123143	-2.0443941193584534	[34]	[14]	-8	hSpCas9	negative selection	10550686
14441205	14441228	19	-	28162770	SKM1	viability	CCAGCTGCTGCTGTACCCCGGGG	PKN1	ENSG00000123143	0.09310940439148141	[69]	[131]	0	hSpCas9	negative selection	10550687
14441244	14441267	19	+	28162770	SKM1	viability	GCTGCGGCGGGAAATCCGCAAGG	PKN1	ENSG00000123143	0.38489854716152505	[106]	[246]	4	hSpCas9	negative selection	10550688
14441262	14441285	19	+	28162770	SKM1	viability	CAAGGAGCTGAAGCTGAAGGAGG	PKN1	ENSG00000123143	-0.47650513199623873	[84]	[107]	-4	hSpCas9	negative selection	10550689
14441306	14441329	19	-	28162770	SKM1	viability	GCTGCGGCCCAGGTCAGTGGTGG	PKN1	ENSG00000123143	0.45810622117072974	[48]	[118]	4	hSpCas9	negative selection	10550690
14441367	14441390	19	-	28162770	SKM1	viability	GCTGGTGCAGCAGGTCGAGGCGG	PKN1	ENSG00000123143	0.6237980550275253	[28]	[78]	6	hSpCas9	negative selection	10550691
14441408	14441431	19	-	28162770	SKM1	viability	CGGGTCGGGAAGCACCACGTGGG	PKN1	ENSG00000123143	0.7629608026991506	[44]	[134]	7	hSpCas9	negative selection	10550692
14441282	14441305	19	+	28162770	SKM1	viability	AGGGTGCTGAGAACCTGCGGCGG	PKN1	ENSG00000123143	0.2399260511211964	[56]	[118]	2	hSpCas9	negative selection	10720049
14446540	14446563	19	+	28162770	SKM1	viability	GCAGCCCCGGATGACACCCAAGG	PKN1	ENSG00000123143	0.10399772053421774	[29]	[56]	1	hSpCas9	negative selection	10720050
14451000	14451023	19	+	28162770	SKM1	viability	GCTGCGAGAAGAGCTCGCTGCGG	PKN1	ENSG00000123143	-0.7000111736433949	[33]	[36]	-5	hSpCas9	negative selection	10720051
14451026	14451049	19	-	28162770	SKM1	viability	GCGGGTGCTGAAGGCAGCGGAGG	PKN1	ENSG00000123143	-2.0443941193584534	[34]	[14]	-8	hSpCas9	negative selection	10720052
14441205	14441228	19	-	28162770	SKM1	viability	CCAGCTGCTGCTGTACCCCGGGG	PKN1	ENSG00000123143	0.09310940439148141	[69]	[131]	0	hSpCas9	negative selection	10720053
14441244	14441267	19	+	28162770	SKM1	viability	GCTGCGGCGGGAAATCCGCAAGG	PKN1	ENSG00000123143	0.38489854716152505	[106]	[246]	4	hSpCas9	negative selection	10720054
14441262	14441285	19	+	28162770	SKM1	viability	CAAGGAGCTGAAGCTGAAGGAGG	PKN1	ENSG00000123143	-0.47650513199623873	[84]	[107]	-4	hSpCas9	negative selection	10720055
14441306	14441329	19	-	28162770	SKM1	viability	GCTGCGGCCCAGGTCAGTGGTGG	PKN1	ENSG00000123143	0.45810622117072974	[48]	[118]	4	hSpCas9	negative selection	10720056
14441367	14441390	19	-	28162770	SKM1	viability	GCTGGTGCAGCAGGTCGAGGCGG	PKN1	ENSG00000123143	0.6237980550275253	[28]	[78]	6	hSpCas9	negative selection	10720057
14441408	14441431	19	-	28162770	SKM1	viability	CGGGTCGGGAAGCACCACGTGGG	PKN1	ENSG00000123143	0.7629608026991506	[44]	[134]	7	hSpCas9	negative selection	10720058
14441282	14441305	19	+	28162770	PL21	viability	AGGGTGCTGAGAACCTGCGGCGG	PKN1	ENSG00000123143	-1.2798533266302934	[211]	[37]	-7	hSpCas9	negative selection	10889415
14446540	14446563	19	+	28162770	PL21	viability	GCAGCCCCGGATGACACCCAAGG	PKN1	ENSG00000123143	-0.06289479134447373	[107]	[44]	0	hSpCas9	negative selection	10889416
14451000	14451023	19	+	28162770	PL21	viability	GCTGCGAGAAGAGCTCGCTGCGG	PKN1	ENSG00000123143	-1.4628253982331092	[170]	[26]	-7	hSpCas9	negative selection	10889417
14451026	14451049	19	-	28162770	PL21	viability	GCGGGTGCTGAAGGCAGCGGAGG	PKN1	ENSG00000123143	0.8782115196019578	[134]	[107]	7	hSpCas9	negative selection	10889418
14441205	14441228	19	-	28162770	PL21	viability	CCAGCTGCTGCTGTACCCCGGGG	PKN1	ENSG00000123143	0.48087602205657276	[269]	[163]	4	hSpCas9	negative selection	10889419
14441244	14441267	19	+	28162770	PL21	viability	GCTGCGGCGGGAAATCCGCAAGG	PKN1	ENSG00000123143	0.5491472434329668	[379]	[241]	5	hSpCas9	negative selection	10889420
14441262	14441285	19	+	28162770	PL21	viability	CAAGGAGCTGAAGCTGAAGGAGG	PKN1	ENSG00000123143	0.49021884333734267	[228]	[139]	4	hSpCas9	negative selection	10889421
14441306	14441329	19	-	28162770	PL21	viability	GCTGCGGCCCAGGTCAGTGGTGG	PKN1	ENSG00000123143	0.4158683055447573	[154]	[89]	3	hSpCas9	negative selection	10889422
14441367	14441390	19	-	28162770	PL21	viability	GCTGGTGCAGCAGGTCGAGGCGG	PKN1	ENSG00000123143	-0.3730457184554826	[121]	[40]	-3	hSpCas9	negative selection	10889423
14441408	14441431	19	-	28162770	PL21	viability	CGGGTCGGGAAGCACCACGTGGG	PKN1	ENSG00000123143	1.6712822156533143	[144]	[200]	9	hSpCas9	negative selection	10889424
14441282	14441305	19	+	28162770	P31FUJ	viability	AGGGTGCTGAGAACCTGCGGCGG	PKN1	ENSG00000123143	0.2567135108237417	[150]	[211]	2	hSpCas9	negative selection	11058781
14446540	14446563	19	+	28162770	P31FUJ	viability	GCAGCCCCGGATGACACCCAAGG	PKN1	ENSG00000123143	0.19346255028771941	[127]	[171]	2	hSpCas9	negative selection	11058782
14451000	14451023	19	+	28162770	P31FUJ	viability	GCTGCGAGAAGAGCTCGCTGCGG	PKN1	ENSG00000123143	-1.4551946257508266	[160]	[68]	-7	hSpCas9	negative selection	11058783
14451026	14451049	19	-	28162770	P31FUJ	viability	GCGGGTGCTGAAGGCAGCGGAGG	PKN1	ENSG00000123143	-1.4818297522542931	[163]	[68]	-7	hSpCas9	negative selection	11058784
14441205	14441228	19	-	28162770	P31FUJ	viability	CCAGCTGCTGCTGTACCCCGGGG	PKN1	ENSG00000123143	0.33968478275971714	[270]	[402]	4	hSpCas9	negative selection	11058785
14441244	14441267	19	+	28162770	P31FUJ	viability	GCTGCGGCGGGAAATCCGCAAGG	PKN1	ENSG00000123143	0.5609059015379261	[348]	[604]	6	hSpCas9	negative selection	11058786
14441262	14441285	19	+	28162770	P31FUJ	viability	CAAGGAGCTGAAGCTGAAGGAGG	PKN1	ENSG00000123143	-0.044685205295681096	[358]	[408]	0	hSpCas9	negative selection	11058787
14441306	14441329	19	-	28162770	P31FUJ	viability	GCTGCGGCCCAGGTCAGTGGTGG	PKN1	ENSG00000123143	0.855145494861324	[174]	[371]	8	hSpCas9	negative selection	11058788
14441367	14441390	19	-	28162770	P31FUJ	viability	GCTGGTGCAGCAGGTCGAGGCGG	PKN1	ENSG00000123143	0.1344067697738502	[206]	[266]	1	hSpCas9	negative selection	11058789
14441408	14441431	19	-	28162770	P31FUJ	viability	CGGGTCGGGAAGCACCACGTGGG	PKN1	ENSG00000123143	0.3239266155778336	[171]	[252]	3	hSpCas9	negative selection	11058790
14441282	14441305	19	+	28162770	OCIAML5	viability	AGGGTGCTGAGAACCTGCGGCGG	PKN1	ENSG00000123143	0.23332492036664754	[81]	[173]	2	hSpCas9	negative selection	11228147
14446540	14446563	19	+	28162770	OCIAML5	viability	GCAGCCCCGGATGACACCCAAGG	PKN1	ENSG00000123143	0.11371771379809015	[63]	[124]	0	hSpCas9	negative selection	11228148
14451000	14451023	19	+	28162770	OCIAML5	viability	GCTGCGAGAAGAGCTCGCTGCGG	PKN1	ENSG00000123143	-0.25167402957323504	[61]	[93]	-2	hSpCas9	negative selection	11228149
14451026	14451049	19	-	28162770	OCIAML5	viability	GCGGGTGCTGAAGGCAGCGGAGG	PKN1	ENSG00000123143	-0.7525308973130826	[97]	[104]	-5	hSpCas9	negative selection	11228150
14441205	14441228	19	-	28162770	OCIAML5	viability	CCAGCTGCTGCTGTACCCCGGGG	PKN1	ENSG00000123143	0.273028649117536	[137]	[300]	2	hSpCas9	negative selection	11228151
14441244	14441267	19	+	28162770	OCIAML5	viability	GCTGCGGCGGGAAATCCGCAAGG	PKN1	ENSG00000123143	0.4497238784522892	[201]	[497]	4	hSpCas9	negative selection	11228152
14441262	14441285	19	+	28162770	OCIAML5	viability	CAAGGAGCTGAAGCTGAAGGAGG	PKN1	ENSG00000123143	0.416750187563803	[165]	[399]	3	hSpCas9	negative selection	11228153
14441306	14441329	19	-	28162770	OCIAML5	viability	GCTGCGGCCCAGGTCAGTGGTGG	PKN1	ENSG00000123143	0.12129830263253627	[81]	[160]	1	hSpCas9	negative selection	11228154
14441367	14441390	19	-	28162770	OCIAML5	viability	GCTGGTGCAGCAGGTCGAGGCGG	PKN1	ENSG00000123143	0.7018690342365348	[93]	[275]	6	hSpCas9	negative selection	11228155
14441408	14441431	19	-	28162770	OCIAML5	viability	CGGGTCGGGAAGCACCACGTGGG	PKN1	ENSG00000123143	0.00965405431015598	[92]	[168]	0	hSpCas9	negative selection	11228156
14441282	14441305	19	+	28162770	EOL1	viability	AGGGTGCTGAGAACCTGCGGCGG	PKN1	ENSG00000123143	-0.9596552293300891	[346]	[93]	-6	hSpCas9	negative selection	11397513
14446540	14446563	19	+	28162770	EOL1	viability	GCAGCCCCGGATGACACCCAAGG	PKN1	ENSG00000123143	-0.4418797834836876	[213]	[82]	-3	hSpCas9	negative selection	11397514
14451000	14451023	19	+	28162770	EOL1	viability	GCTGCGAGAAGAGCTCGCTGCGG	PKN1	ENSG00000123143	-1.855062160004165	[308]	[44]	-8	hSpCas9	negative selection	11397515
14451026	14451049	19	-	28162770	EOL1	viability	GCGGGTGCTGAAGGCAGCGGAGG	PKN1	ENSG00000123143	-0.810719535123646	[282]	[84]	-5	hSpCas9	negative selection	11397516
14441205	14441228	19	-	28162770	EOL1	viability	CCAGCTGCTGCTGTACCCCGGGG	PKN1	ENSG00000123143	0.8334547127775579	[571]	[536]	7	hSpCas9	negative selection	11397517
14441244	14441267	19	+	28162770	EOL1	viability	GCTGCGGCGGGAAATCCGCAAGG	PKN1	ENSG00000123143	0.9762319268594657	[657]	[681]	8	hSpCas9	negative selection	11397518
14441262	14441285	19	+	28162770	EOL1	viability	CAAGGAGCTGAAGCTGAAGGAGG	PKN1	ENSG00000123143	1.0853011271145967	[262]	[293]	8	hSpCas9	negative selection	11397519
14441306	14441329	19	-	28162770	EOL1	viability	GCTGCGGCCCAGGTCAGTGGTGG	PKN1	ENSG00000123143	1.0911976409799857	[195]	[219]	8	hSpCas9	negative selection	11397520
14441367	14441390	19	-	28162770	EOL1	viability	GCTGGTGCAGCAGGTCGAGGCGG	PKN1	ENSG00000123143	0.9395759808028662	[190]	[192]	7	hSpCas9	negative selection	11397521
14441408	14441431	19	-	28162770	EOL1	viability	CGGGTCGGGAAGCACCACGTGGG	PKN1	ENSG00000123143	-1.48403470557101	[222]	[41]	-7	hSpCas9	negative selection	11397522
14441282	14441305	19	+	28162770	MOLM13	viability	AGGGTGCTGAGAACCTGCGGCGG	PKN1	ENSG00000123143	0.3258703766721509	[223]	[202]	2	hSpCas9	negative selection	11566879
14446540	14446563	19	+	28162770	MOLM13	viability	GCAGCCCCGGATGACACCCAAGG	PKN1	ENSG00000123143	-2.1874624470679755	[188]	[29]	-7	hSpCas9	negative selection	11566880
14451000	14451023	19	+	28162770	MOLM13	viability	GCTGCGAGAAGAGCTCGCTGCGG	PKN1	ENSG00000123143	-1.751788655094833	[176]	[37]	-7	hSpCas9	negative selection	11566881
14451026	14451049	19	-	28162770	MOLM13	viability	GCGGGTGCTGAAGGCAGCGGAGG	PKN1	ENSG00000123143	-1.5582629063113895	[166]	[40]	-6	hSpCas9	negative selection	11566882
14441205	14441228	19	-	28162770	MOLM13	viability	CCAGCTGCTGCTGTACCCCGGGG	PKN1	ENSG00000123143	0.9642579589967465	[318]	[449]	7	hSpCas9	negative selection	11566883
14441244	14441267	19	+	28162770	MOLM13	viability	GCTGCGGCGGGAAATCCGCAAGG	PKN1	ENSG00000123143	0.9017859080747384	[512]	[692]	7	hSpCas9	negative selection	11566884
14441262	14441285	19	+	28162770	MOLM13	viability	CAAGGAGCTGAAGCTGAAGGAGG	PKN1	ENSG00000123143	-0.6366665494980109	[328]	[152]	-4	hSpCas9	negative selection	11566885
14441306	14441329	19	-	28162770	MOLM13	viability	GCTGCGGCCCAGGTCAGTGGTGG	PKN1	ENSG00000123143	-0.19452925925657338	[219]	[138]	-1	hSpCas9	negative selection	11566886
14441367	14441390	19	-	28162770	MOLM13	viability	GCTGGTGCAGCAGGTCGAGGCGG	PKN1	ENSG00000123143	-0.3931342053066108	[177]	[97]	-2	hSpCas9	negative selection	11566887
14441408	14441431	19	-	28162770	MOLM13	viability	CGGGTCGGGAAGCACCACGTGGG	PKN1	ENSG00000123143	0.20850275272592922	[157]	[131]	1	hSpCas9	negative selection	11566888
14441282	14441305	19	+	28162770	HEL	viability	AGGGTGCTGAGAACCTGCGGCGG	PKN1	ENSG00000123143	0.2791916479112556	[210]	[163]	2	hSpCas9	negative selection	11736245
14446540	14446563	19	+	28162770	HEL	viability	GCAGCCCCGGATGACACCCAAGG	PKN1	ENSG00000123143	-0.08120008186960959	[146]	[88]	0	hSpCas9	negative selection	11736246
14451000	14451023	19	+	28162770	HEL	viability	GCTGCGAGAAGAGCTCGCTGCGG	PKN1	ENSG00000123143	-0.713954681047682	[209]	[81]	-5	hSpCas9	negative selection	11736247
14451026	14451049	19	-	28162770	HEL	viability	GCGGGTGCTGAAGGCAGCGGAGG	PKN1	ENSG00000123143	-2.229104816508961	[182]	[24]	-8	hSpCas9	negative selection	11736248
14441205	14441228	19	-	28162770	HEL	viability	CCAGCTGCTGCTGTACCCCGGGG	PKN1	ENSG00000123143	0.3173933765552599	[316]	[252]	2	hSpCas9	negative selection	11736249
14441244	14441267	19	+	28162770	HEL	viability	GCTGCGGCGGGAAATCCGCAAGG	PKN1	ENSG00000123143	0.705886550526701	[446]	[466]	6	hSpCas9	negative selection	11736250
14441262	14441285	19	+	28162770	HEL	viability	CAAGGAGCTGAAGCTGAAGGAGG	PKN1	ENSG00000123143	-0.5259032035584822	[280]	[124]	-4	hSpCas9	negative selection	11736251
14441306	14441329	19	-	28162770	HEL	viability	GCTGCGGCCCAGGTCAGTGGTGG	PKN1	ENSG00000123143	0.1269738416382269	[172]	[120]	1	hSpCas9	negative selection	11736252
14441367	14441390	19	-	28162770	HEL	viability	GCTGGTGCAGCAGGTCGAGGCGG	PKN1	ENSG00000123143	-0.9991260599552763	[180]	[57]	-6	hSpCas9	negative selection	11736253
14441408	14441431	19	-	28162770	HEL	viability	CGGGTCGGGAAGCACCACGTGGG	PKN1	ENSG00000123143	-1.8329945989660408	[177]	[31]	-7	hSpCas9	negative selection	11736254
14441282	14441305	19	+	28162770	MV411	viability	AGGGTGCTGAGAACCTGCGGCGG	PKN1	ENSG00000123143	-0.8780933313010837	[143]	[65]	-6	hSpCas9	negative selection	11905611
14446540	14446563	19	+	28162770	MV411	viability	GCAGCCCCGGATGACACCCAAGG	PKN1	ENSG00000123143	0.044345685405263735	[98]	[85]	0	hSpCas9	negative selection	11905612
14451000	14451023	19	+	28162770	MV411	viability	GCTGCGAGAAGAGCTCGCTGCGG	PKN1	ENSG00000123143	-1.4384538587891615	[147]	[45]	-7	hSpCas9	negative selection	11905613
14451026	14451049	19	-	28162770	MV411	viability	GCGGGTGCTGAAGGCAGCGGAGG	PKN1	ENSG00000123143	-1.1881473259001543	[164]	[60]	-6	hSpCas9	negative selection	11905614
14441205	14441228	19	-	28162770	MV411	viability	CCAGCTGCTGCTGTACCCCGGGG	PKN1	ENSG00000123143	-0.0839420194491588	[267]	[212]	0	hSpCas9	negative selection	11905615
14441244	14441267	19	+	28162770	MV411	viability	GCTGCGGCGGGAAATCCGCAAGG	PKN1	ENSG00000123143	0.6840773045468301	[347]	[470]	6	hSpCas9	negative selection	11905616
14441262	14441285	19	+	28162770	MV411	viability	CAAGGAGCTGAAGCTGAAGGAGG	PKN1	ENSG00000123143	-0.029523813093096207	[228]	[188]	0	hSpCas9	negative selection	11905617
14441306	14441329	19	-	28162770	MV411	viability	GCTGCGGCCCAGGTCAGTGGTGG	PKN1	ENSG00000123143	0.44954295797423743	[132]	[152]	4	hSpCas9	negative selection	11905618
14441367	14441390	19	-	28162770	MV411	viability	GCTGGTGCAGCAGGTCGAGGCGG	PKN1	ENSG00000123143	0.7006101789483903	[83]	[114]	6	hSpCas9	negative selection	11905619
14441408	14441431	19	-	28162770	MV411	viability	CGGGTCGGGAAGCACCACGTGGG	PKN1	ENSG00000123143	0.09435822077838607	[148]	[133]	0	hSpCas9	negative selection	11905620
14441282	14441305	19	+	28162770	MONOMAC1	viability	AGGGTGCTGAGAACCTGCGGCGG	PKN1	ENSG00000123143	-0.3386979962831448	[138]	[125]	-3	hSpCas9	negative selection	12074977
14446540	14446563	19	+	28162770	MONOMAC1	viability	GCAGCCCCGGATGACACCCAAGG	PKN1	ENSG00000123143	0.7919920351194432	[65]	[130]	7	hSpCas9	negative selection	12074978
14451000	14451023	19	+	28162770	MONOMAC1	viability	GCTGCGAGAAGAGCTCGCTGCGG	PKN1	ENSG00000123143	-1.3263198640045202	[104]	[47]	-7	hSpCas9	negative selection	12074979
14451026	14451049	19	-	28162770	MONOMAC1	viability	GCGGGTGCTGAAGGCAGCGGAGG	PKN1	ENSG00000123143	-0.5073769676717041	[92]	[74]	-4	hSpCas9	negative selection	12074980
14441205	14441228	19	-	28162770	MONOMAC1	viability	CCAGCTGCTGCTGTACCCCGGGG	PKN1	ENSG00000123143	-0.2051191933574123	[178]	[177]	-2	hSpCas9	negative selection	12074981
14441244	14441267	19	+	28162770	MONOMAC1	viability	GCTGCGGCGGGAAATCCGCAAGG	PKN1	ENSG00000123143	-0.15486739281561412	[235]	[242]	-1	hSpCas9	negative selection	12074982
14441262	14441285	19	+	28162770	MONOMAC1	viability	CAAGGAGCTGAAGCTGAAGGAGG	PKN1	ENSG00000123143	-0.09250626358824698	[172]	[185]	-1	hSpCas9	negative selection	12074983
14441306	14441329	19	-	28162770	MONOMAC1	viability	GCTGCGGCCCAGGTCAGTGGTGG	PKN1	ENSG00000123143	-0.47907221482340323	[106]	[87]	-4	hSpCas9	negative selection	12074984
14441367	14441390	19	-	28162770	MONOMAC1	viability	GCTGGTGCAGCAGGTCGAGGCGG	PKN1	ENSG00000123143	-0.04503375361450368	[62]	[69]	0	hSpCas9	negative selection	12074985
14441408	14441431	19	-	28162770	MONOMAC1	viability	CGGGTCGGGAAGCACCACGTGGG	PKN1	ENSG00000123143	0.6192511997680584	[91]	[161]	6	hSpCas9	negative selection	12074986
14441282	14441305	19	+	28162770	OCIAML2	viability	AGGGTGCTGAGAACCTGCGGCGG	PKN1	ENSG00000123143	0.3462794035286917	[42]	[302]	3	hSpCas9	negative selection	12244343
14446540	14446563	19	+	28162770	OCIAML2	viability	GCAGCCCCGGATGACACCCAAGG	PKN1	ENSG00000123143	0.11433267547899506	[15]	[95]	1	hSpCas9	negative selection	12244344
14451000	14451023	19	+	28162770	OCIAML2	viability	GCTGCGAGAAGAGCTCGCTGCGG	PKN1	ENSG00000123143	-1.190521906049426	[27]	[67]	-7	hSpCas9	negative selection	12244345
14451026	14451049	19	-	28162770	OCIAML2	viability	GCGGGTGCTGAAGGCAGCGGAGG	PKN1	ENSG00000123143	-1.2655153953375489	[35]	[82]	-7	hSpCas9	negative selection	12244346
14441205	14441228	19	-	28162770	OCIAML2	viability	CCAGCTGCTGCTGTACCCCGGGG	PKN1	ENSG00000123143	0.8906607019159747	[46]	[482]	8	hSpCas9	negative selection	12244347
14441244	14441267	19	+	28162770	OCIAML2	viability	GCTGCGGCGGGAAATCCGCAAGG	PKN1	ENSG00000123143	0.155304456535301	[80]	[499]	1	hSpCas9	negative selection	12244348
14441262	14441285	19	+	28162770	OCIAML2	viability	CAAGGAGCTGAAGCTGAAGGAGG	PKN1	ENSG00000123143	-0.02840749663708697	[45]	[249]	0	hSpCas9	negative selection	12244349
14441306	14441329	19	-	28162770	OCIAML2	viability	GCTGCGGCCCAGGTCAGTGGTGG	PKN1	ENSG00000123143	-0.7252026523277589	[33]	[113]	-5	hSpCas9	negative selection	12244350
14441367	14441390	19	-	28162770	OCIAML2	viability	GCTGGTGCAGCAGGTCGAGGCGG	PKN1	ENSG00000123143	0.007417471562482958	[20]	[116]	0	hSpCas9	negative selection	12244351
14441408	14441431	19	-	28162770	OCIAML2	viability	CGGGTCGGGAAGCACCACGTGGG	PKN1	ENSG00000123143	-0.3267940526685096	[30]	[136]	-3	hSpCas9	negative selection	12244352
14441282	14441305	19	+	28162770	OCIAML3	viability	AGGGTGCTGAGAACCTGCGGCGG	PKN1	ENSG00000123143	-1.3618341981951296	[62]	[73]	-7	hSpCas9	negative selection	12413709
14446540	14446563	19	+	28162770	OCIAML3	viability	GCAGCCCCGGATGACACCCAAGG	PKN1	ENSG00000123143	0.1479242067353923	[28]	[96]	1	hSpCas9	negative selection	12413710
14451000	14451023	19	+	28162770	OCIAML3	viability	GCTGCGAGAAGAGCTCGCTGCGG	PKN1	ENSG00000123143	-0.9979045819978066	[42]	[64]	-6	hSpCas9	negative selection	12413711
14451026	14451049	19	-	28162770	OCIAML3	viability	GCGGGTGCTGAAGGCAGCGGAGG	PKN1	ENSG00000123143	-0.6643969682155613	[41]	[79]	-5	hSpCas9	negative selection	12413712
14441205	14441228	19	-	28162770	OCIAML3	viability	CCAGCTGCTGCTGTACCCCGGGG	PKN1	ENSG00000123143	0.4344007748615908	[87]	[358]	4	hSpCas9	negative selection	12413713
14441244	14441267	19	+	28162770	OCIAML3	viability	GCTGCGGCGGGAAATCCGCAAGG	PKN1	ENSG00000123143	0.5045561941594263	[98]	[423]	5	hSpCas9	negative selection	12413714
14441262	14441285	19	+	28162770	OCIAML3	viability	CAAGGAGCTGAAGCTGAAGGAGG	PKN1	ENSG00000123143	0.5331042775791763	[75]	[331]	5	hSpCas9	negative selection	12413715
14441306	14441329	19	-	28162770	OCIAML3	viability	GCTGCGGCCCAGGTCAGTGGTGG	PKN1	ENSG00000123143	0.5398481064106275	[35]	[157]	5	hSpCas9	negative selection	12413716
14441367	14441390	19	-	28162770	OCIAML3	viability	GCTGGTGCAGCAGGTCGAGGCGG	PKN1	ENSG00000123143	-0.2154960170704333	[34]	[90]	-2	hSpCas9	negative selection	12413717
14441408	14441431	19	-	28162770	OCIAML3	viability	CGGGTCGGGAAGCACCACGTGGG	PKN1	ENSG00000123143	0.8687829904030488	[38]	[214]	7	hSpCas9	negative selection	12413718