Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:5586
• Symbol:PKN2
• Description:protein kinase N2

DataSource: http://genomecrispr.dkfz.de/#!/results/PKN2

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
88770363	88770386	1	-	26472758	Jiyoye	viability	GCAGTTGCTGAGCTGTACCATGG	PKN2	ENSG00000065243	0.36486457664790906	[345]	[335]	2	hSpCas9	negative selection	121365
88684607	88684630	1	+	26472758	Jiyoye	viability	GATTCTGCTCACGGAACTGCAGG	PKN2	ENSG00000065243	0.5624536069837842	[131]	[146]	4	hSpCas9	negative selection	121366
88805937	88805960	1	-	26472758	Jiyoye	viability	GAAGCTCGTGGTGGGGCTGGAGG	PKN2	ENSG00000065243	5.473264571963646	[1]	[66]	9	hSpCas9	negative selection	121367
88771434	88771457	1	+	26472758	Jiyoye	viability	AAGTCCTCTTGAACTTCGGATGG	PKN2	ENSG00000065243	-1.6708271304953999	[75]	[17]	-8	hSpCas9	negative selection	121368
88804511	88804534	1	-	26472758	Jiyoye	viability	TCTGCAAATAAAGTACCCTGTGG	PKN2	ENSG00000065243	0.12055415535446362	[110]	[90]	0	hSpCas9	negative selection	121369
88805628	88805651	1	-	26472758	Jiyoye	viability	GGGATGCGTACATCAACCACTGG	PKN2	ENSG00000065243	0.7048559301465585	[191]	[235]	5	hSpCas9	negative selection	121370
88805661	88805684	1	-	26472758	Jiyoye	viability	TCAGACACATACCTAGCTGGAGG	PKN2	ENSG00000065243	0.6260099834291324	[115]	[134]	4	hSpCas9	negative selection	121371
88813660	88813683	1	+	26472758	Jiyoye	viability	GTAATGGAATATGCTGCCGGTGG	PKN2	ENSG00000065243	3.9921378822270293	[0]	[11]	9	hSpCas9	negative selection	121372
88833109	88833132	1	+	26472758	Jiyoye	viability	GGCTAGCGAGAAAGATGCAGAGG	PKN2	ENSG00000065243	-0.42723855277615164	[147]	[82]	-3	hSpCas9	negative selection	121373
88684581	88684604	1	+	26472758	Jiyoye	viability	ATGGCGTCCAACCCCGAACGGGG	PKN2	ENSG00000065243	2.9921378822270297	[11]	[71]	9	hSpCas9	negative selection	121374
88770363	88770386	1	-	26472758	KBM7	viability	GCAGTTGCTGAGCTGTACCATGG	PKN2	ENSG00000065243	0.45518660249054665	[1658,1299]	[1106,802]	5	hSpCas9	negative selection	312483
88684607	88684630	1	+	26472758	KBM7	viability	GATTCTGCTCACGGAACTGCAGG	PKN2	ENSG00000065243	-0.23485364099787187	[769,672]	[283,290]	-2	hSpCas9	negative selection	312484
88805937	88805960	1	-	26472758	KBM7	viability	GAAGCTCGTGGTGGGGCTGGAGG	PKN2	ENSG00000065243	0.5202387645378499	[152,144]	[115,86]	5	hSpCas9	negative selection	312485
88771434	88771457	1	+	26472758	KBM7	viability	AAGTCCTCTTGAACTTCGGATGG	PKN2	ENSG00000065243	0.003003401004886719	[75,100]	[32,50]	0	hSpCas9	negative selection	312486
88804511	88804534	1	-	26472758	KBM7	viability	TCTGCAAATAAAGTACCCTGTGG	PKN2	ENSG00000065243	0.9878851636923525	[327,231]	[289,228]	9	hSpCas9	negative selection	312487
88805628	88805651	1	-	26472758	KBM7	viability	GGGATGCGTACATCAACCACTGG	PKN2	ENSG00000065243	0.09660845199717727	[1120,1146]	[562,582]	0	hSpCas9	negative selection	312488
88805661	88805684	1	-	26472758	KBM7	viability	TCAGACACATACCTAGCTGGAGG	PKN2	ENSG00000065243	0.3846894710830947	[740,597]	[351,458]	4	hSpCas9	negative selection	312489
88813660	88813683	1	+	26472758	KBM7	viability	GTAATGGAATATGCTGCCGGTGG	PKN2	ENSG00000065243	-2.020240476576657	[129,45]	[4,13]	-8	hSpCas9	negative selection	312490
88833109	88833132	1	+	26472758	KBM7	viability	GGCTAGCGAGAAAGATGCAGAGG	PKN2	ENSG00000065243	0.3297046764678101	[509,492]	[244,343]	3	hSpCas9	negative selection	312491
88684581	88684604	1	+	26472758	KBM7	viability	ATGGCGTCCAACCCCGAACGGGG	PKN2	ENSG00000065243	0.7621603466034577	[152,95]	[107,87]	8	hSpCas9	negative selection	312492
88770363	88770386	1	-	26472758	Raji	viability	GCAGTTGCTGAGCTGTACCATGG	PKN2	ENSG00000065243	0.2251370668657393	[681]	[184]	2	hSpCas9	negative selection	503601
88684607	88684630	1	+	26472758	Raji	viability	GATTCTGCTCACGGAACTGCAGG	PKN2	ENSG00000065243	-0.3975053736496858	[402]	[70]	-3	hSpCas9	negative selection	503602
88805937	88805960	1	-	26472758	Raji	viability	GAAGCTCGTGGTGGGGCTGGAGG	PKN2	ENSG00000065243	0.3968901525685846	[71]	[21]	4	hSpCas9	negative selection	503603
88771434	88771457	1	+	26472758	Raji	viability	AAGTCCTCTTGAACTTCGGATGG	PKN2	ENSG00000065243	-0.599569489726167	[110]	[16]	-5	hSpCas9	negative selection	503604
88804511	88804534	1	-	26472758	Raji	viability	TCTGCAAATAAAGTACCCTGTGG	PKN2	ENSG00000065243	1.157136570570699	[113]	[58]	8	hSpCas9	negative selection	503605
88805628	88805651	1	-	26472758	Raji	viability	GGGATGCGTACATCAACCACTGG	PKN2	ENSG00000065243	0.6314218118138163	[394]	[141]	6	hSpCas9	negative selection	503606
88805661	88805684	1	-	26472758	Raji	viability	TCAGACACATACCTAGCTGGAGG	PKN2	ENSG00000065243	-0.20818906447393937	[452]	[90]	-2	hSpCas9	negative selection	503607
88813660	88813683	1	+	26472758	Raji	viability	GTAATGGAATATGCTGCCGGTGG	PKN2	ENSG00000065243	-0.0942503257960512	[45]	[9]	-1	hSpCas9	negative selection	503608
88833109	88833132	1	+	26472758	Raji	viability	GGCTAGCGAGAAAGATGCAGAGG	PKN2	ENSG00000065243	0.7761776268982263	[233]	[92]	7	hSpCas9	negative selection	503609
88684581	88684604	1	+	26472758	Raji	viability	ATGGCGTCCAACCCCGAACGGGG	PKN2	ENSG00000065243	0.31383441284102553	[103]	[29]	3	hSpCas9	negative selection	503610
88770363	88770386	1	-	26472758	K562	viability	GCAGTTGCTGAGCTGTACCATGG	PKN2	ENSG00000065243	0.6547948495754277	[1084]	[1441]	5	hSpCas9	negative selection	694719
88684607	88684630	1	+	26472758	K562	viability	GATTCTGCTCACGGAACTGCAGG	PKN2	ENSG00000065243	0.6800264334280437	[382]	[517]	5	hSpCas9	negative selection	694720
88805937	88805960	1	-	26472758	K562	viability	GAAGCTCGTGGTGGGGCTGGAGG	PKN2	ENSG00000065243	0.25381742566869625	[152]	[153]	2	hSpCas9	negative selection	694721
88771434	88771457	1	+	26472758	K562	viability	AAGTCCTCTTGAACTTCGGATGG	PKN2	ENSG00000065243	0.08395405547320056	[56]	[50]	0	hSpCas9	negative selection	694722
88804511	88804534	1	-	26472758	K562	viability	TCTGCAAATAAAGTACCCTGTGG	PKN2	ENSG00000065243	0.11245338745794176	[285]	[260]	0	hSpCas9	negative selection	694723
88805628	88805651	1	-	26472758	K562	viability	GGGATGCGTACATCAACCACTGG	PKN2	ENSG00000065243	0.7700791496074575	[686]	[988]	6	hSpCas9	negative selection	694724
88805661	88805684	1	-	26472758	K562	viability	TCAGACACATACCTAGCTGGAGG	PKN2	ENSG00000065243	0.66371825379945	[506]	[677]	5	hSpCas9	negative selection	694725
88813660	88813683	1	+	26472758	K562	viability	GTAATGGAATATGCTGCCGGTGG	PKN2	ENSG00000065243	1.7513787163863297	[37]	[107]	9	hSpCas9	negative selection	694726
88833109	88833132	1	+	26472758	K562	viability	GGCTAGCGAGAAAGATGCAGAGG	PKN2	ENSG00000065243	1.2975300641260095	[359]	[746]	9	hSpCas9	negative selection	694727
88684581	88684604	1	+	26472758	K562	viability	ATGGCGTCCAACCCCGAACGGGG	PKN2	ENSG00000065243	0.734223995347263	[140]	[197]	6	hSpCas9	negative selection	694728
88684562	88684585	1	+	26627737	DLD1	viability	GAGTCCATACCGGAGCGCAATGG	PKN2	ENSG00000065243	0.4560248645582405	[261]	[109,206,35]	4	hSpCas9	negative selection	772853
88770363	88770386	1	-	26627737	DLD1	viability	GCAGTTGCTGAGCTGTACCATGG	PKN2	ENSG00000065243	-1.5201228119933223	[1286]	[203,155,71]	-8	hSpCas9	negative selection	772855
88786186	88786209	1	+	26627737	DLD1	viability	CCAGAAGTTTACACTGGAACTGG	PKN2	ENSG00000065243	0.525559111171942	[963]	[285,656,376]	5	hSpCas9	negative selection	772857
88805628	88805651	1	-	26627737	DLD1	viability	GGGATGCGTACATCAACCACTGG	PKN2	ENSG00000065243	0.2805556315448938	[165]	[94,60,36]	3	hSpCas9	negative selection	772859
88807754	88807777	1	+	26627737	DLD1	viability	TGGCTCGAGATGAAGTAGACAGG	PKN2	ENSG00000065243	-0.12403288412619815	[436]	[99,167,111]	-1	hSpCas9	negative selection	772862
88832753	88832776	1	-	26627737	DLD1	viability	ACTTCCTCTTCATCATCACCAGG	PKN2	ENSG00000065243	0.1866009027203821	[129]	[57,26,51]	2	hSpCas9	negative selection	772863
88684562	88684585	1	+	26627737	GBM cells	viability after 5 days	GAGTCCATACCGGAGCGCAATGG	PKN2	ENSG00000065243	0.06883887632799812	[135]	[83,68]	1	hSpCas9	negative selection	855168
88770363	88770386	1	-	26627737	GBM cells	viability after 5 days	GCAGTTGCTGAGCTGTACCATGG	PKN2	ENSG00000065243	-0.6394079007166817	[349]	[130,109]	-7	hSpCas9	negative selection	855170
88786186	88786209	1	+	26627737	GBM cells	viability after 5 days	CCAGAAGTTTACACTGGAACTGG	PKN2	ENSG00000065243	0.42125902681174043	[721]	[515,520]	6	hSpCas9	negative selection	855172
88805628	88805651	1	-	26627737	GBM cells	viability after 5 days	GGGATGCGTACATCAACCACTGG	PKN2	ENSG00000065243	-0.12071493186324678	[73]	[45,26]	-2	hSpCas9	negative selection	855174
88807754	88807777	1	+	26627737	GBM cells	viability after 5 days	TGGCTCGAGATGAAGTAGACAGG	PKN2	ENSG00000065243	0.9888560001984839	[170]	[153,209]	9	hSpCas9	negative selection	855177
88832753	88832776	1	-	26627737	GBM cells	viability after 5 days	ACTTCCTCTTCATCATCACCAGG	PKN2	ENSG00000065243	0.8906933680807171	[87]	[87,86]	9	hSpCas9	negative selection	855178
88684562	88684585	1	+	26627737	GBM cells	viability after 13 days	GAGTCCATACCGGAGCGCAATGG	PKN2	ENSG00000065243	-0.8331348026826829	[135]	[52,31]	-7	hSpCas9	negative selection	937483
88770363	88770386	1	-	26627737	GBM cells	viability after 13 days	GCAGTTGCTGAGCTGTACCATGG	PKN2	ENSG00000065243	-1.027783566960273	[349]	[96,89]	-8	hSpCas9	negative selection	937485
88786186	88786209	1	+	26627737	GBM cells	viability after 13 days	CCAGAAGTTTACACTGGAACTGG	PKN2	ENSG00000065243	0.2261002662498881	[721]	[605,337]	3	hSpCas9	negative selection	937487
88805628	88805651	1	-	26627737	GBM cells	viability after 13 days	GGGATGCGTACATCAACCACTGG	PKN2	ENSG00000065243	-0.2470813421975968	[73]	[40,27]	-3	hSpCas9	negative selection	937489
88807754	88807777	1	+	26627737	GBM cells	viability after 13 days	TGGCTCGAGATGAAGTAGACAGG	PKN2	ENSG00000065243	0.7763327340696423	[170]	[191,131]	8	hSpCas9	negative selection	937492
88832753	88832776	1	-	26627737	GBM cells	viability after 13 days	ACTTCCTCTTCATCATCACCAGG	PKN2	ENSG00000065243	0.2424749122218759	[87]	[61,51]	3	hSpCas9	negative selection	937493
88684562	88684585	1	+	26627737	GBM cells	viability after 21 days	GAGTCCATACCGGAGCGCAATGG	PKN2	ENSG00000065243	-0.3374129584715818	[135]	[58,57]	-3	hSpCas9	negative selection	1019798
88770363	88770386	1	-	26627737	GBM cells	viability after 21 days	GCAGTTGCTGAGCTGTACCATGG	PKN2	ENSG00000065243	-2.2382698785760655	[349]	[44,35]	-9	hSpCas9	negative selection	1019800
88786186	88786209	1	+	26627737	GBM cells	viability after 21 days	CCAGAAGTTTACACTGGAACTGG	PKN2	ENSG00000065243	-0.15664557668563495	[721]	[377,327]	-1	hSpCas9	negative selection	1019802
88805628	88805651	1	-	26627737	GBM cells	viability after 21 days	GGGATGCGTACATCAACCACTGG	PKN2	ENSG00000065243	-1.2945739232064002	[73]	[18,13]	-8	hSpCas9	negative selection	1019804
88807754	88807777	1	+	26627737	GBM cells	viability after 21 days	TGGCTCGAGATGAAGTAGACAGG	PKN2	ENSG00000065243	0.5961223896834963	[170]	[141,138]	6	hSpCas9	negative selection	1019807
88832753	88832776	1	-	26627737	GBM cells	viability after 21 days	ACTTCCTCTTCATCATCACCAGG	PKN2	ENSG00000065243	0.20971935477928882	[87]	[71,39]	2	hSpCas9	negative selection	1019808
88684562	88684585	1	+	26627737	RPE1	viability after 9 days	GAGTCCATACCGGAGCGCAATGG	PKN2	ENSG00000065243	0.04926136686715055	[475]	[127,187]	0	hSpCas9	negative selection	1102113
88770363	88770386	1	-	26627737	RPE1	viability after 9 days	GCAGTTGCTGAGCTGTACCATGG	PKN2	ENSG00000065243	-1.2488055509765923	[1210]	[176,136]	-7	hSpCas9	negative selection	1102115
88786186	88786209	1	+	26627737	RPE1	viability after 9 days	CCAGAAGTTTACACTGGAACTGG	PKN2	ENSG00000065243	1.4666724763368533	[1141]	[995,977]	8	hSpCas9	negative selection	1102117
88805628	88805651	1	-	26627737	RPE1	viability after 9 days	GGGATGCGTACATCAACCACTGG	PKN2	ENSG00000065243	4.396064130393542	[1]	[10,15]	9	hSpCas9	negative selection	1102119
88807754	88807777	1	+	26627737	RPE1	viability after 9 days	TGGCTCGAGATGAAGTAGACAGG	PKN2	ENSG00000065243	-0.6434446398118664	[908]	[179,184]	-4	hSpCas9	negative selection	1102122
88832753	88832776	1	-	26627737	RPE1	viability after 9 days	ACTTCCTCTTCATCATCACCAGG	PKN2	ENSG00000065243	-1.42138905815142	[260]	[33,25]	-7	hSpCas9	negative selection	1102123
88684562	88684585	1	+	26627737	RPE1	viability after 12 days	GAGTCCATACCGGAGCGCAATGG	PKN2	ENSG00000065243	-0.14856417324829863	[475]	[59,173]	-1	hSpCas9	negative selection	1184428
88770363	88770386	1	-	26627737	RPE1	viability after 12 days	GCAGTTGCTGAGCTGTACCATGG	PKN2	ENSG00000065243	-1.1811084416946573	[1210]	[142,143]	-7	hSpCas9	negative selection	1184430
88786186	88786209	1	+	26627737	RPE1	viability after 12 days	CCAGAAGTTTACACTGGAACTGG	PKN2	ENSG00000065243	1.5400340137014636	[1141]	[1001,775]	8	hSpCas9	negative selection	1184432
88805628	88805651	1	-	26627737	RPE1	viability after 12 days	GGGATGCGTACATCAACCACTGG	PKN2	ENSG00000065243	6.553914719279788	[1]	[15,86]	9	hSpCas9	negative selection	1184434
88807754	88807777	1	+	26627737	RPE1	viability after 12 days	TGGCTCGAGATGAAGTAGACAGG	PKN2	ENSG00000065243	-0.3060032012035372	[908]	[147,249]	-2	hSpCas9	negative selection	1184437
88832753	88832776	1	-	26627737	RPE1	viability after 12 days	ACTTCCTCTTCATCATCACCAGG	PKN2	ENSG00000065243	-1.9256872471477882	[260]	[16,19]	-8	hSpCas9	negative selection	1184438
88684562	88684585	1	+	26627737	RPE1	viability after 15 days	GAGTCCATACCGGAGCGCAATGG	PKN2	ENSG00000065243	-0.9883927514323988	[475]	[18,114]	-6	hSpCas9	negative selection	1266743
88770363	88770386	1	-	26627737	RPE1	viability after 15 days	GCAGTTGCTGAGCTGTACCATGG	PKN2	ENSG00000065243	-1.5802325211455814	[1210]	[110,117]	-7	hSpCas9	negative selection	1266745
88786186	88786209	1	+	26627737	RPE1	viability after 15 days	CCAGAAGTTTACACTGGAACTGG	PKN2	ENSG00000065243	1.6661731094957528	[1141]	[1291,767]	8	hSpCas9	negative selection	1266747
88805628	88805651	1	-	26627737	RPE1	viability after 15 days	GGGATGCGTACATCAACCACTGG	PKN2	ENSG00000065243	6.113247760928005	[1]	[57,20]	9	hSpCas9	negative selection	1266749
88807754	88807777	1	+	26627737	RPE1	viability after 15 days	TGGCTCGAGATGAAGTAGACAGG	PKN2	ENSG00000065243	-0.6318201620899303	[908]	[168,162]	-4	hSpCas9	negative selection	1266752
88832753	88832776	1	-	26627737	RPE1	viability after 15 days	ACTTCCTCTTCATCATCACCAGG	PKN2	ENSG00000065243	-0.8920019675767523	[260]	[79,0]	-5	hSpCas9	negative selection	1266753
88684562	88684585	1	+	26627737	RPE1	viability after 18 days	GAGTCCATACCGGAGCGCAATGG	PKN2	ENSG00000065243	-0.6702037549791152	[475]	[28,135]	-4	hSpCas9	negative selection	1349058
88770363	88770386	1	-	26627737	RPE1	viability after 18 days	GCAGTTGCTGAGCTGTACCATGG	PKN2	ENSG00000065243	-1.902706576952695	[1210]	[69,105]	-8	hSpCas9	negative selection	1349060
88786186	88786209	1	+	26627737	RPE1	viability after 18 days	CCAGAAGTTTACACTGGAACTGG	PKN2	ENSG00000065243	1.6859385440698615	[1141]	[979,1003]	8	hSpCas9	negative selection	1349062
88805628	88805651	1	-	26627737	RPE1	viability after 18 days	GGGATGCGTACATCAACCACTGG	PKN2	ENSG00000065243	5.48060113013842	[1]	[26,20]	9	hSpCas9	negative selection	1349064
88807754	88807777	1	+	26627737	RPE1	viability after 18 days	TGGCTCGAGATGAAGTAGACAGG	PKN2	ENSG00000065243	-0.7990138595965162	[908]	[96,187]	-5	hSpCas9	negative selection	1349067
88832753	88832776	1	-	26627737	RPE1	viability after 18 days	ACTTCCTCTTCATCATCACCAGG	PKN2	ENSG00000065243	-3.19045194091008	[260]	[13,0]	-9	hSpCas9	negative selection	1349068
88684562	88684585	1	+	26627737	HeLa	viability after 8 days	GAGTCCATACCGGAGCGCAATGG	PKN2	ENSG00000065243	-0.8136652854699201	[381]	[116,111,61]	-7	hSpCas9	negative selection	1431373
88770363	88770386	1	-	26627737	HeLa	viability after 8 days	GCAGTTGCTGAGCTGTACCATGG	PKN2	ENSG00000065243	-1.1040107265696375	[565]	[73,163,97]	-8	hSpCas9	negative selection	1431375
88786186	88786209	1	+	26627737	HeLa	viability after 8 days	CCAGAAGTTTACACTGGAACTGG	PKN2	ENSG00000065243	-0.31021914072072154	[1104]	[502,375,314]	-3	hSpCas9	negative selection	1431377
88805628	88805651	1	-	26627737	HeLa	viability after 8 days	GGGATGCGTACATCAACCACTGG	PKN2	ENSG00000065243	-1.16837158911519	[31]	[19,0,0]	-8	hSpCas9	negative selection	1431379
88807754	88807777	1	+	26627737	HeLa	viability after 8 days	TGGCTCGAGATGAAGTAGACAGG	PKN2	ENSG00000065243	0.17258123250361224	[508]	[343,195,230]	1	hSpCas9	negative selection	1431382
88832753	88832776	1	-	26627737	HeLa	viability after 8 days	ACTTCCTCTTCATCATCACCAGG	PKN2	ENSG00000065243	-0.6138652973134389	[120]	[30,44,26]	-6	hSpCas9	negative selection	1431383
88684562	88684585	1	+	26627737	HeLa	viability after 12 days	GAGTCCATACCGGAGCGCAATGG	PKN2	ENSG00000065243	-0.7959712489669484	[381]	[108,55,111]	-6	hSpCas9	negative selection	1513688
88770363	88770386	1	-	26627737	HeLa	viability after 12 days	GCAGTTGCTGAGCTGTACCATGG	PKN2	ENSG00000065243	-0.5393309396298009	[565]	[140,238,93]	-5	hSpCas9	negative selection	1513690
88786186	88786209	1	+	26627737	HeLa	viability after 12 days	CCAGAAGTTTACACTGGAACTGG	PKN2	ENSG00000065243	0.48819346618334825	[1104]	[682,629,610]	4	hSpCas9	negative selection	1513692
88805628	88805651	1	-	26627737	HeLa	viability after 12 days	GGGATGCGTACATCAACCACTGG	PKN2	ENSG00000065243	0.48201298762278144	[31]	[0,26,25]	4	hSpCas9	negative selection	1513694
88807754	88807777	1	+	26627737	HeLa	viability after 12 days	TGGCTCGAGATGAAGTAGACAGG	PKN2	ENSG00000065243	0.5717851348162318	[508]	[487,218,245]	5	hSpCas9	negative selection	1513697
88832753	88832776	1	-	26627737	HeLa	viability after 12 days	ACTTCCTCTTCATCATCACCAGG	PKN2	ENSG00000065243	-1.237520285361255	[120]	[9,23,28]	-8	hSpCas9	negative selection	1513698
88684562	88684585	1	+	26627737	HeLa	viability after 15 days	GAGTCCATACCGGAGCGCAATGG	PKN2	ENSG00000065243	-0.6052275116954708	[381]	[166,58,77]	-5	hSpCas9	negative selection	1596003
88770363	88770386	1	-	26627737	HeLa	viability after 15 days	GCAGTTGCTGAGCTGTACCATGG	PKN2	ENSG00000065243	-0.6626306466317251	[565]	[117,173,144]	-5	hSpCas9	negative selection	1596005
88786186	88786209	1	+	26627737	HeLa	viability after 15 days	CCAGAAGTTTACACTGGAACTGG	PKN2	ENSG00000065243	0.2138572600298574	[1104]	[218,599,768]	1	hSpCas9	negative selection	1596007
88805628	88805651	1	-	26627737	HeLa	viability after 15 days	GGGATGCGTACATCAACCACTGG	PKN2	ENSG00000065243	1.8579332839225213	[31]	[134,0,0]	9	hSpCas9	negative selection	1596009
88807754	88807777	1	+	26627737	HeLa	viability after 15 days	TGGCTCGAGATGAAGTAGACAGG	PKN2	ENSG00000065243	-0.12977054111722272	[508]	[125,180,267]	-1	hSpCas9	negative selection	1596012
88832753	88832776	1	-	26627737	HeLa	viability after 15 days	ACTTCCTCTTCATCATCACCAGG	PKN2	ENSG00000065243	-1.9563408449888438	[120]	[32,1,1]	-9	hSpCas9	negative selection	1596013
88684562	88684585	1	+	26627737	HeLa	viability after 18 days	GAGTCCATACCGGAGCGCAATGG	PKN2	ENSG00000065243	-0.5353704522725077	[381]	[120,49,77]	-5	hSpCas9	negative selection	1678318
88770363	88770386	1	-	26627737	HeLa	viability after 18 days	GCAGTTGCTGAGCTGTACCATGG	PKN2	ENSG00000065243	-0.6668932622053522	[565]	[75,146,144]	-5	hSpCas9	negative selection	1678320
88786186	88786209	1	+	26627737	HeLa	viability after 18 days	CCAGAAGTTTACACTGGAACTGG	PKN2	ENSG00000065243	0.24452802276109575	[1104]	[150,518,768]	2	hSpCas9	negative selection	1678322
88805628	88805651	1	-	26627737	HeLa	viability after 18 days	GGGATGCGTACATCAACCACTGG	PKN2	ENSG00000065243	1.9127448635610618	[31]	[93,0,0]	9	hSpCas9	negative selection	1678324
88807754	88807777	1	+	26627737	HeLa	viability after 18 days	TGGCTCGAGATGAAGTAGACAGG	PKN2	ENSG00000065243	-0.12211526122442029	[508]	[91,142,267]	-1	hSpCas9	negative selection	1678327
88832753	88832776	1	-	26627737	HeLa	viability after 18 days	ACTTCCTCTTCATCATCACCAGG	PKN2	ENSG00000065243	-2.069763635743678	[120]	[19,1,1]	-9	hSpCas9	negative selection	1678328
88684562	88684585	1	+	26627737	HCT116	viability after 6 days	GAGTCCATACCGGAGCGCAATGG	PKN2	ENSG00000065243	3.1953652452124555	[104]	[263,88]	9	hSpCas9	negative selection	1760633
88770363	88770386	1	-	26627737	HCT116	viability after 6 days	GCAGTTGCTGAGCTGTACCATGG	PKN2	ENSG00000065243	-0.7288084333658212	[1438]	[53,181]	-4	hSpCas9	negative selection	1760635
88786186	88786209	1	+	26627737	HCT116	viability after 6 days	CCAGAAGTTTACACTGGAACTGG	PKN2	ENSG00000065243	1.7561937894890902	[968]	[288,638]	8	hSpCas9	negative selection	1760637
88805628	88805651	1	-	26627737	HCT116	viability after 6 days	GGGATGCGTACATCAACCACTGG	PKN2	ENSG00000065243	2.0967665967607036	[275]	[66,250]	8	hSpCas9	negative selection	1760639
88807754	88807777	1	+	26627737	HCT116	viability after 6 days	TGGCTCGAGATGAAGTAGACAGG	PKN2	ENSG00000065243	2.672105199324088	[484]	[1154,116]	9	hSpCas9	negative selection	1760642
88832753	88832776	1	-	26627737	HCT116	viability after 6 days	ACTTCCTCTTCATCATCACCAGG	PKN2	ENSG00000065243	-1.8984020528658745	[351]	[19,11]	-8	hSpCas9	negative selection	1760643
88684562	88684585	1	+	26627737	HCT116	viability after 8 days	GAGTCCATACCGGAGCGCAATGG	PKN2	ENSG00000065243	0.2532222932576347	[169]	[110,117,105]	3	hSpCas9	negative selection	1842948
88770363	88770386	1	-	26627737	HCT116	viability after 8 days	GCAGTTGCTGAGCTGTACCATGG	PKN2	ENSG00000065243	-0.08846043584432908	[378]	[164,169,252]	-1	hSpCas9	negative selection	1842950
88786186	88786209	1	+	26627737	HCT116	viability after 8 days	CCAGAAGTTTACACTGGAACTGG	PKN2	ENSG00000065243	-0.14903056357378208	[795]	[337,395,450]	-2	hSpCas9	negative selection	1842952
88805628	88805651	1	-	26627737	HCT116	viability after 8 days	GGGATGCGTACATCAACCACTGG	PKN2	ENSG00000065243	-0.6266165685843796	[115]	[76,19,27]	-6	hSpCas9	negative selection	1842954
88807754	88807777	1	+	26627737	HCT116	viability after 8 days	TGGCTCGAGATGAAGTAGACAGG	PKN2	ENSG00000065243	0.42564552032378644	[308]	[180,172,329]	4	hSpCas9	negative selection	1842957
88832753	88832776	1	-	26627737	HCT116	viability after 8 days	ACTTCCTCTTCATCATCACCAGG	PKN2	ENSG00000065243	-0.7577558066483399	[139]	[39,69,26]	-7	hSpCas9	negative selection	1842958
88684562	88684585	1	+	26627737	HCT116	viability after 9 days	GAGTCCATACCGGAGCGCAATGG	PKN2	ENSG00000065243	2.286022506719326	[104]	[143,130]	9	hSpCas9	negative selection	1925263
88770363	88770386	1	-	26627737	HCT116	viability after 9 days	GCAGTTGCTGAGCTGTACCATGG	PKN2	ENSG00000065243	-1.0243064904402004	[1438]	[308,93]	-6	hSpCas9	negative selection	1925265
88786186	88786209	1	+	26627737	HCT116	viability after 9 days	CCAGAAGTTTACACTGGAACTGG	PKN2	ENSG00000065243	0.72218121794243	[968]	[642,255]	5	hSpCas9	negative selection	1925267
88805628	88805651	1	-	26627737	HCT116	viability after 9 days	GGGATGCGTACATCAACCACTGG	PKN2	ENSG00000065243	0.013276743648447775	[275]	[127,31]	0	hSpCas9	negative selection	1925269
88807754	88807777	1	+	26627737	HCT116	viability after 9 days	TGGCTCGAGATGAAGTAGACAGG	PKN2	ENSG00000065243	0.4440566979370099	[484]	[307,71]	3	hSpCas9	negative selection	1925272
88832753	88832776	1	-	26627737	HCT116	viability after 9 days	ACTTCCTCTTCATCATCACCAGG	PKN2	ENSG00000065243	-6.0269295787465715	[351]	[1,0]	-9	hSpCas9	negative selection	1925273
88684562	88684585	1	+	26627737	HCT116	viability after 12 days	GAGTCCATACCGGAGCGCAATGG	PKN2	ENSG00000065243	-0.07300966583296398	[169]	[80,37,134]	0	hSpCas9	negative selection	2007578
88770363	88770386	1	-	26627737	HCT116	viability after 12 days	GCAGTTGCTGAGCTGTACCATGG	PKN2	ENSG00000065243	-0.1632126196740307	[378]	[163,184,185]	-2	hSpCas9	negative selection	2007580
88786186	88786209	1	+	26627737	HCT116	viability after 12 days	CCAGAAGTTTACACTGGAACTGG	PKN2	ENSG00000065243	-0.47507499155599686	[795]	[270,280,352]	-5	hSpCas9	negative selection	2007582
88805628	88805651	1	-	26627737	HCT116	viability after 12 days	GGGATGCGTACATCAACCACTGG	PKN2	ENSG00000065243	0.15501539435285405	[115]	[88,35,75]	1	hSpCas9	negative selection	2007584
88807754	88807777	1	+	26627737	HCT116	viability after 12 days	TGGCTCGAGATGAAGTAGACAGG	PKN2	ENSG00000065243	0.2570909674161053	[308]	[139,278,169]	2	hSpCas9	negative selection	2007587
88832753	88832776	1	-	26627737	HCT116	viability after 12 days	ACTTCCTCTTCATCATCACCAGG	PKN2	ENSG00000065243	-0.4072419348673906	[139]	[91,45,24]	-4	hSpCas9	negative selection	2007588
88684562	88684585	1	+	26627737	HCT116	viability after 15 days	GAGTCCATACCGGAGCGCAATGG	PKN2	ENSG00000065243	0.11234699821881011	[169]	[114,116,85]	1	hSpCas9	negative selection	2089893
88770363	88770386	1	-	26627737	HCT116	viability after 15 days	GCAGTTGCTGAGCTGTACCATGG	PKN2	ENSG00000065243	0.5441812632874277	[378]	[254,241,445]	5	hSpCas9	negative selection	2089895
88786186	88786209	1	+	26627737	HCT116	viability after 15 days	CCAGAAGTTTACACTGGAACTGG	PKN2	ENSG00000065243	-0.12545678446626507	[795]	[487,309,466]	-1	hSpCas9	negative selection	2089897
88805628	88805651	1	-	26627737	HCT116	viability after 15 days	GGGATGCGTACATCAACCACTGG	PKN2	ENSG00000065243	0.19709843296892515	[115]	[113,68,50]	2	hSpCas9	negative selection	2089899
88807754	88807777	1	+	26627737	HCT116	viability after 15 days	TGGCTCGAGATGAAGTAGACAGG	PKN2	ENSG00000065243	0.2267465114462916	[308]	[310,153,170]	2	hSpCas9	negative selection	2089902
88832753	88832776	1	-	26627737	HCT116	viability after 15 days	ACTTCCTCTTCATCATCACCAGG	PKN2	ENSG00000065243	-0.4442532609785492	[139]	[97,23,59]	-4	hSpCas9	negative selection	2089903
88684562	88684585	1	+	26627737	HCT116	viability after 18 days	GAGTCCATACCGGAGCGCAATGG	PKN2	ENSG00000065243	-0.10889881253978784	[169]	[57,71,99]	-1	hSpCas9	negative selection	2172208
88770363	88770386	1	-	26627737	HCT116	viability after 18 days	GCAGTTGCTGAGCTGTACCATGG	PKN2	ENSG00000065243	0.2943309476929614	[378]	[258,159,260]	2	hSpCas9	negative selection	2172210
88786186	88786209	1	+	26627737	HCT116	viability after 18 days	CCAGAAGTTTACACTGGAACTGG	PKN2	ENSG00000065243	-0.43719275936373214	[795]	[293,225,338]	-4	hSpCas9	negative selection	2172212
88805628	88805651	1	-	26627737	HCT116	viability after 18 days	GGGATGCGTACATCAACCACTGG	PKN2	ENSG00000065243	-0.9179462211518723	[115]	[41,24,21]	-7	hSpCas9	negative selection	2172214
88807754	88807777	1	+	26627737	HCT116	viability after 18 days	TGGCTCGAGATGAAGTAGACAGG	PKN2	ENSG00000065243	0.7050685775665616	[308]	[213,217,302]	6	hSpCas9	negative selection	2172217
88832753	88832776	1	-	26627737	HCT116	viability after 18 days	ACTTCCTCTTCATCATCACCAGG	PKN2	ENSG00000065243	-0.23611503997181083	[139]	[117,35,17]	-2	hSpCas9	negative selection	2172218
88684607	88684630	1	+	24336569	HL60	viability	GATTCTGCTCACGGAACTGCAGG	PKN2	ENSG00000065243	1.2610906448484238	[124]	[633]	8	hSpCas9	negative selection	2284403
88741053	88741076	1	+	24336569	HL60	viability	TACAATGGTGCAGCAGAAATTGG	PKN2	ENSG00000065243	0.12798926500005364	[351]	[813]	1	hSpCas9	negative selection	2284404
88741065	88741088	1	+	24336569	HL60	viability	GCAGAAATTGGATGATATCAAGG	PKN2	ENSG00000065243	0.05445691985882939	[1077]	[2368]	0	hSpCas9	negative selection	2284405
88741088	88741111	1	+	24336569	HL60	viability	ATCGAATTAAGAGAGAAATAAGG	PKN2	ENSG00000065243	-0.7634940193102173	[437]	[545]	-6	hSpCas9	negative selection	2284406
88741267	88741290	1	+	24336569	HL60	viability	TCAGATCCAGAAGATATTACAGG	PKN2	ENSG00000065243	0.3251611588337473	[773]	[2051]	3	hSpCas9	negative selection	2284407
88741273	88741296	1	-	24336569	HL60	viability	ACTATACCTGTAATATCTTCTGG	PKN2	ENSG00000065243	-0.6626048903976441	[376]	[503]	-6	hSpCas9	negative selection	2284408
88760226	88760249	1	-	24336569	HL60	viability	TTGGAGTATCTGGAGTCCTTGGG	PKN2	ENSG00000065243	0.7567848293744917	[329]	[1179]	6	hSpCas9	negative selection	2284409
88760236	88760259	1	-	24336569	HL60	viability	GGGTCATTATTTGGAGTATCTGG	PKN2	ENSG00000065243	1.379392402115229	[367]	[2025]	8	hSpCas9	negative selection	2284410
88760245	88760268	1	-	24336569	HL60	viability	GAACAACGAGGGTCATTATTTGG	PKN2	ENSG00000065243	-0.16787885244636958	[773]	[1457]	-1	hSpCas9	negative selection	2284411
88760256	88760279	1	-	24336569	HL60	viability	TGTTGCTAGTAGAACAACGAGGG	PKN2	ENSG00000065243	0.6376878777743666	[382]	[1260]	5	hSpCas9	negative selection	2284412
88684607	88684630	1	+	24336569	KBM7	viability	GATTCTGCTCACGGAACTGCAGG	PKN2	ENSG00000065243	0.11946139617501106	[161]	[479]	1	hSpCas9	negative selection	2351580
88741053	88741076	1	+	24336569	KBM7	viability	TACAATGGTGCAGCAGAAATTGG	PKN2	ENSG00000065243	0.23049270856375498	[469]	[1503]	2	hSpCas9	negative selection	2351581
88741065	88741088	1	+	24336569	KBM7	viability	GCAGAAATTGGATGATATCAAGG	PKN2	ENSG00000065243	0.44978862494112937	[607]	[2264]	4	hSpCas9	negative selection	2351582
88741088	88741111	1	+	24336569	KBM7	viability	ATCGAATTAAGAGAGAAATAAGG	PKN2	ENSG00000065243	1.0876057431472155	[171]	[996]	8	hSpCas9	negative selection	2351583
88741267	88741290	1	+	24336569	KBM7	viability	TCAGATCCAGAAGATATTACAGG	PKN2	ENSG00000065243	1.128406679529175	[617]	[3684]	8	hSpCas9	negative selection	2351584
88741273	88741296	1	-	24336569	KBM7	viability	ACTATACCTGTAATATCTTCTGG	PKN2	ENSG00000065243	0.5632496809385681	[364]	[1470]	5	hSpCas9	negative selection	2351585
88760226	88760249	1	-	24336569	KBM7	viability	TTGGAGTATCTGGAGTCCTTGGG	PKN2	ENSG00000065243	1.0232122842529627	[275]	[1529]	8	hSpCas9	negative selection	2351586
88760236	88760259	1	-	24336569	KBM7	viability	GGGTCATTATTTGGAGTATCTGG	PKN2	ENSG00000065243	0.8628124038413567	[451]	[2241]	7	hSpCas9	negative selection	2351587
88760245	88760268	1	-	24336569	KBM7	viability	GAACAACGAGGGTCATTATTTGG	PKN2	ENSG00000065243	0.0360664032371219	[520]	[1456]	0	hSpCas9	negative selection	2351588
88760256	88760279	1	-	24336569	KBM7	viability	TGTTGCTAGTAGAACAACGAGGG	PKN2	ENSG00000065243	0.6572735409107371	[324]	[1397]	6	hSpCas9	negative selection	2351589
88741087	88741111	1	+	24717434	HeLa	essential genes for diphteria toxin toxicity	GATCGAATTAAGAGAGAAATAAGG	PKN2	ENSG00000065243	1.3545530303144657	[1139,931,893]	[0,0,0]	4	hSpCas9	positive selection	2381159
88741087	88741111	1	+	24717434	HeLa	essential genes for diphteria toxin toxicity	GATCGAATTAAGAGAGAAATAAGG	PKN2	ENSG00000065243	1.3545530303144657	[1139,931,893]	[0,0,0]	4	hSpCas9	positive selection	2381160
88684584	88684606	1	+	24717434	HeLa	essential genes for diphteria toxin toxicity	GCGTCCAACCCCGAACGGGGGG	PKN2	ENSG00000065243	4.649351658374442	[138,134,29]	[0,0,0]	7	hSpCas9	positive selection	2381161
88684584	88684606	1	+	24717434	HeLa	essential genes for diphteria toxin toxicity	GCGTCCAACCCCGAACGGGGGG	PKN2	ENSG00000065243	4.649351658374442	[138,134,29]	[0,0,0]	7	hSpCas9	positive selection	2381162
88741066	88741088	1	+	24717434	HeLa	essential genes for diphteria toxin toxicity	CAGAAATTGGATGATATCAAGG	PKN2	ENSG00000065243	4.094897298385291	[5450,5108,5366]	[25,46,34]	7	hSpCas9	positive selection	2381163
88741066	88741088	1	+	24717434	HeLa	essential genes for diphteria toxin toxicity	CAGAAATTGGATGATATCAAGG	PKN2	ENSG00000065243	4.094897298385291	[5450,5108,5366]	[25,46,34]	7	hSpCas9	positive selection	2381164
88741087	88741111	1	+	24717434	HeLa	essential genes for PA/LFnDTA toxicity	GATCGAATTAAGAGAGAAATAAGG	PKN2	ENSG00000065243	1.3542445732944557	[1139,931,893]	[0,0,0]	3	hSpCas9	positive selection	2382448
88741087	88741111	1	+	24717434	HeLa	essential genes for PA/LFnDTA toxicity	GATCGAATTAAGAGAGAAATAAGG	PKN2	ENSG00000065243	1.3542445732944557	[1139,931,893]	[0,0,0]	3	hSpCas9	positive selection	2382449
88684584	88684606	1	+	24717434	HeLa	essential genes for PA/LFnDTA toxicity	GCGTCCAACCCCGAACGGGGGG	PKN2	ENSG00000065243	4.6465795513359085	[138,134,29]	[0,0,0]	7	hSpCas9	positive selection	2382450
88684584	88684606	1	+	24717434	HeLa	essential genes for PA/LFnDTA toxicity	GCGTCCAACCCCGAACGGGGGG	PKN2	ENSG00000065243	4.6465795513359085	[138,134,29]	[0,0,0]	7	hSpCas9	positive selection	2382451
88741066	88741088	1	+	24717434	HeLa	essential genes for PA/LFnDTA toxicity	CAGAAATTGGATGATATCAAGG	PKN2	ENSG00000065243	4.026433375846822	[5450,5108,5366]	[100,0,0]	7	hSpCas9	positive selection	2382452
88741066	88741088	1	+	24717434	HeLa	essential genes for PA/LFnDTA toxicity	CAGAAATTGGATGATATCAAGG	PKN2	ENSG00000065243	4.026433375846822	[5450,5108,5366]	[100,0,0]	7	hSpCas9	positive selection	2382453
88702049	88702072	1	-	25494202	A375	resistance to PLX-4720 (puromycin)	CAGGAGAATCACTTGAGCCCAGG	PKN2	ENSG00000065243	1.6338811116880798	[2,7]	[1,4]	6	dCas9-VP64	positive selection	2394908
88718359	88718382	1	+	25494202	A375	resistance to PLX-4720 (puromycin)	AGGGACATTTAAGTCTGCAGAAG	PKN2	ENSG00000065243	0.7916196845249337	[134,243]	[42,103]	3	dCas9-VP64	positive selection	2419362
88822603	88822626	1	+	25494202	A375	resistance to PLX-4720 (puromycin)	GAGTTTCGCTCTTGTCACCCAAG	PKN2	ENSG00000065243	0.7275722083534555	[14,18]	[4,6]	3	dCas9-VP64	positive selection	2454131
88806245	88806268	1	-	25494202	A375	resistance to PLX-4720 (puromycin)	CAGGAGAATCGCTTGAATCCGGG	PKN2	ENSG00000065243	1.579452491414227	[20,39]	[3,36]	6	dCas9-VP64	positive selection	2477154
88702049	88702072	1	-	25494202	A375	resistance to PLX-4720 (zeocin)	CAGGAGAATCACTTGAGCCCAGG	PKN2	ENSG00000065243	0.9117627085384212	[38,78]	[28,41]	6	dCas9-VP64	positive selection	2490163
88718359	88718382	1	+	25494202	A375	resistance to PLX-4720 (zeocin)	AGGGACATTTAAGTCTGCAGAAG	PKN2	ENSG00000065243	-0.5761746865528519	[375,276]	[90,52]	-6	dCas9-VP64	positive selection	2514617
88822603	88822626	1	+	25494202	A375	resistance to PLX-4720 (zeocin)	GAGTTTCGCTCTTGTCACCCAAG	PKN2	ENSG00000065243	0.3552301064276102	[39,27]	[14,12]	3	dCas9-VP64	positive selection	2549386
88806245	88806268	1	-	25494202	A375	resistance to PLX-4720 (zeocin)	CAGGAGAATCGCTTGAATCCGGG	PKN2	ENSG00000065243	0.3334805796334224	[96,125]	[24,64]	2	dCas9-VP64	positive selection	2572409
88741006	88741029	1	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCACTCACATTCTCAGAAAACGG	PKN2	ENSG00000065243	-0.10717341084040022	[4,4]	[4,3]	-1	hSpCas9	positive selection	3011605
88770363	88770386	1	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCAGTTGCTGAGCTGTACCATGG	PKN2	ENSG00000065243	0.043316528732056714	[2,2]	[1,1]	0	hSpCas9	positive selection	3011606
88804497	88804520	1	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TGTCTCTATTTGGAACCACAGGG	PKN2	ENSG00000065243	0.19047098058018525	[3,3]	[4,2]	4	hSpCas9	positive selection	3011607
88760257	88760280	1	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TTGTTGCTAGTAGAACAACGAGG	PKN2	ENSG00000065243	-0.5185866127336267	[0,1]	[0,0]	-6	hSpCas9	positive selection	3011608
88741006	88741029	1	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCACTCACATTCTCAGAAAACGG	PKN2	ENSG00000065243	-0.4135737459230881	[4,4]	[4,0]	-6	hSpCas9	positive selection	3079463
88770363	88770386	1	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCAGTTGCTGAGCTGTACCATGG	PKN2	ENSG00000065243	0.1901570384109249	[2,2]	[2,1]	3	hSpCas9	positive selection	3079464
88804497	88804520	1	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TGTCTCTATTTGGAACCACAGGG	PKN2	ENSG00000065243	-0.36000782677461046	[3,3]	[2,1]	-5	hSpCas9	positive selection	3079465
88760257	88760280	1	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TTGTTGCTAGTAGAACAACGAGG	PKN2	ENSG00000065243	-0.031723513073289356	[0,0]	[0,0]	0	hSpCas9	positive selection	3079466
88770414	88770437		+	24336571	A375	resistance to PLX after 7 days	CATACGAATGCAGATTCTTCAGG	PKN2	ENSG00000065243	0.009891556730846185	[18,25]	[24,19]	0	hSpCas9	positive selection	3135875
88770363	88770386		-	24336571	A375	resistance to PLX after 7 days	GCAGTTGCTGAGCTGTACCATGG	PKN2	ENSG00000065243	0.04695733590835688	[7,9]	[8,9]	1	hSpCas9	positive selection	3135876
88760268	88760291		+	24336571	A375	resistance to PLX after 7 days	TACTAGCAACAATAGATTGAAGG	PKN2	ENSG00000065243	-0.035323911775032246	[5,5]	[5,6]	-1	hSpCas9	positive selection	3135877
88760257	88760280		-	24336571	A375	resistance to PLX after 7 days	TTGTTGCTAGTAGAACAACGAGG	PKN2	ENSG00000065243	-0.07429413588526868	[4,4]	[4,3]	-2	hSpCas9	positive selection	3135878
88770414	88770437		+	24336571	A375	resistance to PLX after 14 days	CATACGAATGCAGATTCTTCAGG	PKN2	ENSG00000065243	-0.8471002101714582	[11,27]	[4,4]	-8	hSpCas9	positive selection	3193668
88770363	88770386		-	24336571	A375	resistance to PLX after 14 days	GCAGTTGCTGAGCTGTACCATGG	PKN2	ENSG00000065243	1.4047376127553108	[3,9]	[12,4]	8	hSpCas9	positive selection	3193669
88760268	88760291		+	24336571	A375	resistance to PLX after 14 days	TACTAGCAACAATAGATTGAAGG	PKN2	ENSG00000065243	0.7846047603361361	[3,8]	[4,5]	6	hSpCas9	positive selection	3193670
88760257	88760280		-	24336571	A375	resistance to PLX after 14 days	TTGTTGCTAGTAGAACAACGAGG	PKN2	ENSG00000065243	0.5055908418668327	[2,3]	[1,1]	5	hSpCas9	positive selection	3193671
88770414	88770437		+	24336571	A375	viability after 7 days	CATACGAATGCAGATTCTTCAGG	PKN2	ENSG00000065243	0.5830324072493113	[15]	[18,25]	8	hSpCas9	negative selection	3251461
88770363	88770386		-	24336571	A375	viability after 7 days	GCAGTTGCTGAGCTGTACCATGG	PKN2	ENSG00000065243	-0.8021444720356559	[16]	[7,9]	-8	hSpCas9	negative selection	3251462
88760268	88760291		+	24336571	A375	viability after 7 days	TACTAGCAACAATAGATTGAAGG	PKN2	ENSG00000065243	-0.852995895345822	[11]	[5,5]	-8	hSpCas9	negative selection	3251463
88760257	88760280		-	24336571	A375	viability after 7 days	TTGTTGCTAGTAGAACAACGAGG	PKN2	ENSG00000065243	0.4299612720546846	[3]	[4,4]	6	hSpCas9	negative selection	3251464
88770414	88770437		+	24336571	A375	viability after 14 days	CATACGAATGCAGATTCTTCAGG	PKN2	ENSG00000065243	0.45056049002276544	[15]	[11,27]	6	hSpCas9	negative selection	3309254
88770363	88770386		-	24336571	A375	viability after 14 days	GCAGTTGCTGAGCTGTACCATGG	PKN2	ENSG00000065243	-1.1014117799480998	[16]	[3,9]	-8	hSpCas9	negative selection	3309255
88760268	88760291		+	24336571	A375	viability after 14 days	TACTAGCAACAATAGATTGAAGG	PKN2	ENSG00000065243	-0.7512608239821101	[11]	[3,8]	-7	hSpCas9	negative selection	3309256
88760257	88760280		-	24336571	A375	viability after 14 days	TTGTTGCTAGTAGAACAACGAGG	PKN2	ENSG00000065243	0.048008014929384224	[3]	[2,3]	0	hSpCas9	negative selection	3309257
88770363	88770386	1	-	27383988	293T	resistance to West Nile virus (flavivirus)	GCAGTTGCTGAGCTGTACCATGG	PKN2	ENSG00000065243	0.009398698002249677	[151,151]	[0,0]	0	hSpCas9	positive selection	3386064
88771430	88771453	1	+	27383988	293T	resistance to West Nile virus (flavivirus)	TGATAAGTCCTCTTGAACTTCGG	PKN2	ENSG00000065243	-0.7760967900916153	[261,261]	[0,0]	-5	hSpCas9	positive selection	3386065
88760268	88760291	1	+	27383988	293T	resistance to West Nile virus (flavivirus)	TACTAGCAACAATAGATTGAAGG	PKN2	ENSG00000065243	2.1280431945008687	[34,34]	[0,0]	7	hSpCas9	positive selection	3386066
88741006	88741029	1	-	26780180	HT29	viability (Avana library 4 designs)	GCACTCACATTCTCAGAAAACGG	PKN2	ENSG00000065243	0.0914954561829077	[]	[]	0	hSpCas9	negative selection	3449696
88770363	88770386	1	-	26780180	HT29	viability (Avana library 4 designs)	GCAGTTGCTGAGCTGTACCATGG	PKN2	ENSG00000065243	2.63555662944577	[]	[]	8	hSpCas9	negative selection	3449697
88804496	88804519	1	+	26780180	HT29	viability (Avana library 4 designs)	TGTCTCTATTTGGAACCACAGGG	PKN2	ENSG00000065243	2.88273186578627	[]	[]	8	hSpCas9	negative selection	3449698
88760257	88760280	1	-	26780180	HT29	viability (Avana library 4 designs)	TTGTTGCTAGTAGAACAACGAGG	PKN2	ENSG00000065243	0.12007950763958	[]	[]	0	hSpCas9	negative selection	3449699
88770363	88770386	1	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCAGTTGCTGAGCTGTACCATGG	PKN2	ENSG00000065243	1.51328986093831	[]	[]	2	hSpCas9	negative selection	3544580
88804496	88804519	1	+	26780180	A375	viability (Avana lentiCRISPRv2)	TGTCTCTATTTGGAACCACAGGG	PKN2	ENSG00000065243	-8.29810906570853	[]	[]	-7	hSpCas9	negative selection	3544581
88741006	88741029	1	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCACTCACATTCTCAGAAAACGG	PKN2	ENSG00000065243	-5.24126706366148	[]	[]	-5	hSpCas9	negative selection	3544582
88760257	88760280	1	-	26780180	A375	viability (Avana lentiCRISPRv2)	TTGTTGCTAGTAGAACAACGAGG	PKN2	ENSG00000065243	-0.354114445505049	[]	[]	0	hSpCas9	negative selection	3544583
88771813	88771836	1	-	26780180	A375	viability (Avana lentiCRISPRv2)	GTAGATATCATACTTTGACGTGG	PKN2	ENSG00000065243	-2.10277757948707	[]	[]	-3	hSpCas9	negative selection	3544584
88771430	88771453	1	+	26780180	A375	viability (Avana lentiCRISPRv2)	TGATAAGTCCTCTTGAACTTCGG	PKN2	ENSG00000065243	-2.5612628031929	[]	[]	-3	hSpCas9	negative selection	3544585
88770363	88770386	1	-	26780180	A375	viability (Avana lentiGuide)	GCAGTTGCTGAGCTGTACCATGG	PKN2	ENSG00000065243	-0.222382968907274	[]	[]	0	hSpCas9	negative selection	3653239
88804496	88804519	1	+	26780180	A375	viability (Avana lentiGuide)	TGTCTCTATTTGGAACCACAGGG	PKN2	ENSG00000065243	1.14752185225774	[]	[]	1	hSpCas9	negative selection	3653240
88741006	88741029	1	-	26780180	A375	viability (Avana lentiGuide)	GCACTCACATTCTCAGAAAACGG	PKN2	ENSG00000065243	0.375821189818723	[]	[]	0	hSpCas9	negative selection	3653241
88760257	88760280	1	-	26780180	A375	viability (Avana lentiGuide)	TTGTTGCTAGTAGAACAACGAGG	PKN2	ENSG00000065243	19.4378188407373	[]	[]	8	hSpCas9	negative selection	3653242
88771813	88771836	1	-	26780180	A375	viability (Avana lentiGuide)	GTAGATATCATACTTTGACGTGG	PKN2	ENSG00000065243	8.86749742109499	[]	[]	6	hSpCas9	negative selection	3653243
88771430	88771453	1	+	26780180	A375	viability (Avana lentiGuide)	TGATAAGTCCTCTTGAACTTCGG	PKN2	ENSG00000065243	5.20445413802347	[]	[]	4	hSpCas9	negative selection	3653244
88770363	88770386	1	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCAGTTGCTGAGCTGTACCATGG	PKN2	ENSG00000065243	-0.06928045850977305	[4]	[4,3]	-1	hSpCas9	positive selection	3761898
88804496	88804519	1	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TGTCTCTATTTGGAACCACAGGG	PKN2	ENSG00000065243	-0.7470132651274457	[6]	[2,3]	-8	hSpCas9	positive selection	3761899
88741006	88741029	1	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCACTCACATTCTCAGAAAACGG	PKN2	ENSG00000065243	-0.4172272009346674	[6]	[4,3]	-6	hSpCas9	positive selection	3761900
88760257	88760280	1	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TTGTTGCTAGTAGAACAACGAGG	PKN2	ENSG00000065243	-0.2574577494440871	[4]	[4,2]	-4	hSpCas9	positive selection	3761901
88771813	88771836	1	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GTAGATATCATACTTTGACGTGG	PKN2	ENSG00000065243	-0.5150741728927332	[7]	[4,4]	-6	hSpCas9	positive selection	3761902
88771430	88771453	1	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TGATAAGTCCTCTTGAACTTCGG	PKN2	ENSG00000065243	-0.3501194074668229	[6]	[5,4]	-5	hSpCas9	positive selection	3761903
88770363	88770386	1	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCAGTTGCTGAGCTGTACCATGG	PKN2	ENSG00000065243	-0.6090019018398805	[4]	[1,1]	-7	hSpCas9	positive selection	3870505
88804496	88804519	1	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TGTCTCTATTTGGAACCACAGGG	PKN2	ENSG00000065243	-0.3717557519665561	[5]	[3,2]	-5	hSpCas9	positive selection	3870506
88741006	88741029	1	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCACTCACATTCTCAGAAAACGG	PKN2	ENSG00000065243	0.16124667634383794	[6]	[6,5]	4	hSpCas9	positive selection	3870507
88760257	88760280	1	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TTGTTGCTAGTAGAACAACGAGG	PKN2	ENSG00000065243	-1.2042531145581918	[3]	[0,0]	-9	hSpCas9	positive selection	3870508
88771813	88771836	1	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GTAGATATCATACTTTGACGTGG	PKN2	ENSG00000065243	0.08001365987374591	[5]	[4,5]	1	hSpCas9	positive selection	3870509
88771430	88771453	1	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TGATAAGTCCTCTTGAACTTCGG	PKN2	ENSG00000065243	-0.3284260244850725	[5]	[3,3]	-4	hSpCas9	positive selection	3870510
88770414	88770437	1	+	26780180	A375	viability	CATACGAATGCAGATTCTTCAGG	PKN2	ENSG00000065243	1.10682175923917	[]	[]	5	hSpCas9	negative selection	3981322
88770363	88770386	1	-	26780180	A375	viability	GCAGTTGCTGAGCTGTACCATGG	PKN2	ENSG00000065243	1.85436973316104	[]	[]	9	hSpCas9	negative selection	3981323
88760268	88760291	1	+	26780180	A375	viability	TACTAGCAACAATAGATTGAAGG	PKN2	ENSG00000065243	0.868479644430395	[]	[]	3	hSpCas9	negative selection	3981324
88771438	88771461	1	-	26780180	A375	viability	TCTTCCATCCGAAGTTCAAGAGG	PKN2	ENSG00000065243	1.0106208498364	[]	[]	5	hSpCas9	negative selection	3981325
88771430	88771453	1	+	26780180	A375	viability	TGATAAGTCCTCTTGAACTTCGG	PKN2	ENSG00000065243	1.61517131148783	[]	[]	8	hSpCas9	negative selection	3981326
88760257	88760280	1	-	26780180	A375	viability	TTGTTGCTAGTAGAACAACGAGG	PKN2	ENSG00000065243	1.01354241351965	[]	[]	5	hSpCas9	negative selection	3981327
88770414	88770437	1	+	26780180	HT29	viability (GeCKOv2 library)	CATACGAATGCAGATTCTTCAGG	PKN2	ENSG00000065243	1.09767079787486	[]	[]	5	hSpCas9	negative selection	4089288
88770363	88770386	1	-	26780180	HT29	viability (GeCKOv2 library)	GCAGTTGCTGAGCTGTACCATGG	PKN2	ENSG00000065243	2.30762293642805	[]	[]	9	hSpCas9	negative selection	4089289
88760268	88760291	1	+	26780180	HT29	viability (GeCKOv2 library)	TACTAGCAACAATAGATTGAAGG	PKN2	ENSG00000065243	1.36020370179769	[]	[]	7	hSpCas9	negative selection	4089290
88771438	88771461	1	-	26780180	HT29	viability (GeCKOv2 library)	TCTTCCATCCGAAGTTCAAGAGG	PKN2	ENSG00000065243	1.48391981515285	[]	[]	7	hSpCas9	negative selection	4089291
88771430	88771453	1	+	26780180	HT29	viability (GeCKOv2 library)	TGATAAGTCCTCTTGAACTTCGG	PKN2	ENSG00000065243	2.16185860942977	[]	[]	9	hSpCas9	negative selection	4089292
88760257	88760280	1	-	26780180	HT29	viability (GeCKOv2 library)	TTGTTGCTAGTAGAACAACGAGG	PKN2	ENSG00000065243	0.748353503748842	[]	[]	3	hSpCas9	negative selection	4089293
88770414	88770437	1	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CATACGAATGCAGATTCTTCAGG	PKN2	ENSG00000065243	0.011892716307116276	[3]	[2,2]	0	hSpCas9	positive selection	4160853
88770363	88770386	1	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GCAGTTGCTGAGCTGTACCATGG	PKN2	ENSG00000065243	0.004822891369655739	[3]	[1,2]	0	hSpCas9	positive selection	4160854
88760268	88760291	1	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TACTAGCAACAATAGATTGAAGG	PKN2	ENSG00000065243	-0.18775217524917906	[3]	[0,2]	-4	hSpCas9	positive selection	4160855
88760257	88760280	1	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TTGTTGCTAGTAGAACAACGAGG	PKN2	ENSG00000065243	-0.5016086515541215	[2]	[0,0]	-8	hSpCas9	positive selection	4160856
88770414	88770437	1	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CATACGAATGCAGATTCTTCAGG	PKN2	ENSG00000065243	0.017146267118643005	[4]	[3,2,1,0]	0	hSpCas9	positive selection	4224875
88770363	88770386	1	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GCAGTTGCTGAGCTGTACCATGG	PKN2	ENSG00000065243	0.3220125734496906	[3]	[4,1,1,0]	2	hSpCas9	positive selection	4224876
88760268	88760291	1	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TACTAGCAACAATAGATTGAAGG	PKN2	ENSG00000065243	0.3151892290854911	[2]	[2,2,0,0]	2	hSpCas9	positive selection	4224877
88760257	88760280	1	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TTGTTGCTAGTAGAACAACGAGG	PKN2	ENSG00000065243	0.6278255434676524	[2]	[1,1,2,0]	4	hSpCas9	positive selection	4224878
88760257	88760280	1	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TTGTTGCTAGTAGAACAACGAGG	PKN2	ENSG00000065243	-0.12358367664768619	[2]	[2,0]	-2	hSpCas9	positive selection	4290489
88770414	88770437	1	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CATACGAATGCAGATTCTTCAGG	PKN2	ENSG00000065243	-0.06687040243613494	[2]	[2,1]	-1	hSpCas9	positive selection	4290490
88771438	88771461	1	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TCTTCCATCCGAAGTTCAAGAGG	PKN2	ENSG00000065243	-0.07040245476234339	[2]	[2,0]	-1	hSpCas9	positive selection	4290491
88770363	88770386	1	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GCAGTTGCTGAGCTGTACCATGG	PKN2	ENSG00000065243	-0.22716472564370385	[3]	[2,1]	-4	hSpCas9	positive selection	4354741
88771430	88771453	1	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TGATAAGTCCTCTTGAACTTCGG	PKN2	ENSG00000065243	-0.2955387436551845	[3]	[3,1]	-6	hSpCas9	positive selection	4354742
88760268	88760291	1	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TACTAGCAACAATAGATTGAAGG	PKN2	ENSG00000065243	0.7712843406303302	[1]	[0,3]	9	hSpCas9	positive selection	4354743
88760256	88760278	1	-	27760321	OCIAML3	viability	GTTGCTAGTAGAACAACGAGGG	PKN2	ENSG00000065243	0.2899836034681945	[225,186]	[173,225]	3	hSpCas9	negative selection	4428156
88771813	88771835	1	-	27760321	OCIAML3	viability	TAGATATCATACTTTGACGTGG	PKN2	ENSG00000065243	0.286773465470175	[54,51]	[54,45]	3	hSpCas9	negative selection	4428157
88786138	88786160	1	+	27760321	OCIAML3	viability	TGTGGTTGGCCAAACTAGCTGG	PKN2	ENSG00000065243	0.15062368750854985	[526,505]	[528,344]	1	hSpCas9	negative selection	4428158
88804382	88804404	1	+	27760321	OCIAML3	viability	TTATCCTAGTCACGTGAACTGG	PKN2	ENSG00000065243	-0.16484248817521208	[241,238]	[159,178]	-2	hSpCas9	negative selection	4428159
88804470	88804492	1	+	27760321	OCIAML3	viability	TTTTAGACAACCAACGGCATGG	PKN2	ENSG00000065243	-0.03942564076353827	[229,181]	[127,191]	0	hSpCas9	negative selection	4428160
88760256	88760278	1	-	27760321	OCIAML2	viability	GTTGCTAGTAGAACAACGAGGG	PKN2	ENSG00000065243	-0.40330472537625695	[225,186]	[120,131]	-5	hSpCas9	negative selection	4511619
88771813	88771835	1	-	27760321	OCIAML2	viability	TAGATATCATACTTTGACGTGG	PKN2	ENSG00000065243	-0.8545630658536618	[54,51]	[29,15]	-7	hSpCas9	negative selection	4511620
88786138	88786160	1	+	27760321	OCIAML2	viability	TGTGGTTGGCCAAACTAGCTGG	PKN2	ENSG00000065243	0.4655891049049079	[526,505]	[570,586]	6	hSpCas9	negative selection	4511621
88804382	88804404	1	+	27760321	OCIAML2	viability	TTATCCTAGTCACGTGAACTGG	PKN2	ENSG00000065243	0.12906441733562157	[241,238]	[161,280]	1	hSpCas9	negative selection	4511622
88804470	88804492	1	+	27760321	OCIAML2	viability	TTTTAGACAACCAACGGCATGG	PKN2	ENSG00000065243	0.7285045782718764	[229,181]	[238,320]	8	hSpCas9	negative selection	4511623
88760256	88760278	1	-	27760321	MV411	viability	GTTGCTAGTAGAACAACGAGGG	PKN2	ENSG00000065243	0.5810047287766017	[225,186]	[122,322]	4	hSpCas9	negative selection	4595082
88771813	88771835	1	-	27760321	MV411	viability	TAGATATCATACTTTGACGTGG	PKN2	ENSG00000065243	-2.1086320391325244	[54,51]	[0,18]	-8	hSpCas9	negative selection	4595083
88786138	88786160	1	+	27760321	MV411	viability	TGTGGTTGGCCAAACTAGCTGG	PKN2	ENSG00000065243	1.2950665709051865	[526,505]	[511,1326]	8	hSpCas9	negative selection	4595084
88804382	88804404	1	+	27760321	MV411	viability	TTATCCTAGTCACGTGAACTGG	PKN2	ENSG00000065243	0.08209128396116216	[241,238]	[245,51]	0	hSpCas9	negative selection	4595085
88804470	88804492	1	+	27760321	MV411	viability	TTTTAGACAACCAACGGCATGG	PKN2	ENSG00000065243	-0.14994128244415084	[229,181]	[62,209]	-1	hSpCas9	negative selection	4595086
88760256	88760278	1	-	27760321	HL60	viability	GTTGCTAGTAGAACAACGAGGG	PKN2	ENSG00000065243	2.960498315155342	[225,186]	[1958,615]	9	hSpCas9	negative selection	4678545
88771813	88771835	1	-	27760321	HL60	viability	TAGATATCATACTTTGACGTGG	PKN2	ENSG00000065243	0.1067207754129802	[54,51]	[33,60]	1	hSpCas9	negative selection	4678546
88786138	88786160	1	+	27760321	HL60	viability	TGTGGTTGGCCAAACTAGCTGG	PKN2	ENSG00000065243	0.2124581826350568	[526,505]	[477,501]	2	hSpCas9	negative selection	4678547
88804382	88804404	1	+	27760321	HL60	viability	TTATCCTAGTCACGTGAACTGG	PKN2	ENSG00000065243	-0.7765882975746418	[241,238]	[114,114]	-7	hSpCas9	negative selection	4678548
88804470	88804492	1	+	27760321	HL60	viability	TTTTAGACAACCAACGGCATGG	PKN2	ENSG00000065243	0.03178939111410517	[229,181]	[135,207]	0	hSpCas9	negative selection	4678549
88760256	88760278	1	-	27760321	HT1080	viability	GTTGCTAGTAGAACAACGAGGG	PKN2	ENSG00000065243	-3.434321662370299	[186,145]	[8,2]	-7	hSpCas9	negative selection	4762008
88771813	88771835	1	-	27760321	HT1080	viability	TAGATATCATACTTTGACGTGG	PKN2	ENSG00000065243	-4.2122524602739	[51,40]	[0,0]	-8	hSpCas9	negative selection	4762009
88786138	88786160	1	+	27760321	HT1080	viability	TGTGGTTGGCCAAACTAGCTGG	PKN2	ENSG00000065243	-1.4530501827480116	[505,394]	[34,98]	-5	hSpCas9	negative selection	4762010
88804382	88804404	1	+	27760321	HT1080	viability	TTATCCTAGTCACGTGAACTGG	PKN2	ENSG00000065243	-1.1684791717469618	[238,186]	[0,77]	-4	hSpCas9	negative selection	4762011
88804470	88804492	1	+	27760321	HT1080	viability	TTTTAGACAACCAACGGCATGG	PKN2	ENSG00000065243	-2.494356240835437	[181,141]	[20,0]	-7	hSpCas9	negative selection	4762012
88760256	88760278	1	-	27760321	HT29	viability after 7 days	GTTGCTAGTAGAACAACGAGGG	PKN2	ENSG00000065243	-0.6456032804346847	[186,145]	[265,33,128]	-7	hSpCas9	negative selection	4845471
88771813	88771835	1	-	27760321	HT29	viability after 7 days	TAGATATCATACTTTGACGTGG	PKN2	ENSG00000065243	-2.532221466412367	[51,40]	[4,6,17]	-9	hSpCas9	negative selection	4845472
88786138	88786160	1	+	27760321	HT29	viability after 7 days	TGTGGTTGGCCAAACTAGCTGG	PKN2	ENSG00000065243	-0.1515801589557419	[505,394]	[598,782,202]	-2	hSpCas9	negative selection	4845473
88804382	88804404	1	+	27760321	HT29	viability after 7 days	TTATCCTAGTCACGTGAACTGG	PKN2	ENSG00000065243	-1.0851952020817253	[238,186]	[160,207,25]	-8	hSpCas9	negative selection	4845474
88804470	88804492	1	+	27760321	HT29	viability after 7 days	TTTTAGACAACCAACGGCATGG	PKN2	ENSG00000065243	-0.48892615270263295	[181,141]	[175,125,146]	-6	hSpCas9	negative selection	4845475
88760256	88760278	1	-	27760321	HT29	viability after 25 days	GTTGCTAGTAGAACAACGAGGG	PKN2	ENSG00000065243	-1.6524474228121873	[186,145]	[48,65,67]	-7	hSpCas9	negative selection	4928934
88771813	88771835	1	-	27760321	HT29	viability after 25 days	TAGATATCATACTTTGACGTGG	PKN2	ENSG00000065243	-1.1114413316968608	[51,40]	[28,32,9]	-7	hSpCas9	negative selection	4928935
88786138	88786160	1	+	27760321	HT29	viability after 25 days	TGTGGTTGGCCAAACTAGCTGG	PKN2	ENSG00000065243	-1.7391636318858634	[505,394]	[73,251,139]	-7	hSpCas9	negative selection	4928936
88804382	88804404	1	+	27760321	HT29	viability after 25 days	TTATCCTAGTCACGTGAACTGG	PKN2	ENSG00000065243	-0.9042820281369452	[238,186]	[129,138,119]	-6	hSpCas9	negative selection	4928937
88804470	88804492	1	+	27760321	HT29	viability after 25 days	TTTTAGACAACCAACGGCATGG	PKN2	ENSG00000065243	-1.5707371240142374	[181,141]	[57,24,108]	-7	hSpCas9	negative selection	4928938
88760256	88760278	1	-	27760321	HT29	viability after 22 days	GTTGCTAGTAGAACAACGAGGG	PKN2	ENSG00000065243	-1.7472858073681679	[186,145]	[21,88,61]	-8	hSpCas9	negative selection	5012397
88771813	88771835	1	-	27760321	HT29	viability after 22 days	TAGATATCATACTTTGACGTGG	PKN2	ENSG00000065243	-1.5943798105570042	[51,40]	[0,23,28]	-7	hSpCas9	negative selection	5012398
88786138	88786160	1	+	27760321	HT29	viability after 22 days	TGTGGTTGGCCAAACTAGCTGG	PKN2	ENSG00000065243	-1.1836414524275212	[505,394]	[73,495,120]	-7	hSpCas9	negative selection	5012399
88804382	88804404	1	+	27760321	HT29	viability after 22 days	TTATCCTAGTCACGTGAACTGG	PKN2	ENSG00000065243	-1.7585915003527637	[238,186]	[46,103,67]	-8	hSpCas9	negative selection	5012400
88804470	88804492	1	+	27760321	HT29	viability after 22 days	TTTTAGACAACCAACGGCATGG	PKN2	ENSG00000065243	-2.9695989175416386	[181,141]	[12,36,21]	-8	hSpCas9	negative selection	5012401
88760256	88760278	1	-	27760321	HT29	viability after 19 days	GTTGCTAGTAGAACAACGAGGG	PKN2	ENSG00000065243	-1.3137292257972988	[186,145]	[184,56,1]	-7	hSpCas9	negative selection	5095860
88771813	88771835	1	-	27760321	HT29	viability after 19 days	TAGATATCATACTTTGACGTGG	PKN2	ENSG00000065243	0.6333661729222593	[51,40]	[37,70,131]	6	hSpCas9	negative selection	5095861
88786138	88786160	1	+	27760321	HT29	viability after 19 days	TGTGGTTGGCCAAACTAGCTGG	PKN2	ENSG00000065243	-1.015021904676313	[505,394]	[274,376,119]	-6	hSpCas9	negative selection	5095862
88804382	88804404	1	+	27760321	HT29	viability after 19 days	TTATCCTAGTCACGTGAACTGG	PKN2	ENSG00000065243	0.10151406759239268	[238,186]	[345,402,51]	0	hSpCas9	negative selection	5095863
88804470	88804492	1	+	27760321	HT29	viability after 19 days	TTTTAGACAACCAACGGCATGG	PKN2	ENSG00000065243	-1.32288656590105	[181,141]	[61,7,147]	-7	hSpCas9	negative selection	5095864
88760256	88760278	1	-	27760321	HT29	viability after 16 days	GTTGCTAGTAGAACAACGAGGG	PKN2	ENSG00000065243	-0.85885310258075	[186,145]	[76,52,176]	-6	hSpCas9	negative selection	5179323
88771813	88771835	1	-	27760321	HT29	viability after 16 days	TAGATATCATACTTTGACGTGG	PKN2	ENSG00000065243	-0.5064788381109775	[51,40]	[18,84,2]	-5	hSpCas9	negative selection	5179324
88786138	88786160	1	+	27760321	HT29	viability after 16 days	TGTGGTTGGCCAAACTAGCTGG	PKN2	ENSG00000065243	-0.5000972750743894	[505,394]	[249,433,372]	-5	hSpCas9	negative selection	5179325
88804382	88804404	1	+	27760321	HT29	viability after 16 days	TTATCCTAGTCACGTGAACTGG	PKN2	ENSG00000065243	-0.9135273756675166	[238,186]	[58,248,61]	-7	hSpCas9	negative selection	5179326
88804470	88804492	1	+	27760321	HT29	viability after 16 days	TTTTAGACAACCAACGGCATGG	PKN2	ENSG00000065243	-1.3968892981459482	[181,141]	[107,36,65]	-7	hSpCas9	negative selection	5179327
88760256	88760278	1	-	27760321	HT29	viability after 13 days	GTTGCTAGTAGAACAACGAGGG	PKN2	ENSG00000065243	-1.1429723504360976	[186,145]	[27,120,111]	-7	hSpCas9	negative selection	5262786
88771813	88771835	1	-	27760321	HT29	viability after 13 days	TAGATATCATACTTTGACGTGG	PKN2	ENSG00000065243	-0.661928223751219	[51,40]	[23,37,39]	-6	hSpCas9	negative selection	5262787
88786138	88786160	1	+	27760321	HT29	viability after 13 days	TGTGGTTGGCCAAACTAGCTGG	PKN2	ENSG00000065243	-0.7108771303466184	[505,394]	[338,353,267]	-6	hSpCas9	negative selection	5262788
88804382	88804404	1	+	27760321	HT29	viability after 13 days	TTATCCTAGTCACGTGAACTGG	PKN2	ENSG00000065243	-1.2581161357550577	[238,186]	[119,121,69]	-8	hSpCas9	negative selection	5262789
88804470	88804492	1	+	27760321	HT29	viability after 13 days	TTTTAGACAACCAACGGCATGG	PKN2	ENSG00000065243	-0.9046727585938381	[181,141]	[64,97,135]	-7	hSpCas9	negative selection	5262790
88760256	88760278	1	-	27760321	HT29	viability after 10 days	GTTGCTAGTAGAACAACGAGGG	PKN2	ENSG00000065243	-0.6515158496041842	[186,145]	[214,34,143]	-6	hSpCas9	negative selection	5346249
88771813	88771835	1	-	27760321	HT29	viability after 10 days	TAGATATCATACTTTGACGTGG	PKN2	ENSG00000065243	-1.4441082592091132	[51,40]	[10,24,27]	-8	hSpCas9	negative selection	5346250
88786138	88786160	1	+	27760321	HT29	viability after 10 days	TGTGGTTGGCCAAACTAGCTGG	PKN2	ENSG00000065243	0.1622656809207862	[505,394]	[671,605,609]	2	hSpCas9	negative selection	5346251
88804382	88804404	1	+	27760321	HT29	viability after 10 days	TTATCCTAGTCACGTGAACTGG	PKN2	ENSG00000065243	-0.9585449065557989	[238,186]	[190,120,98]	-7	hSpCas9	negative selection	5346252
88804470	88804492	1	+	27760321	HT29	viability after 10 days	TTTTAGACAACCAACGGCATGG	PKN2	ENSG00000065243	-0.5275805061091725	[181,141]	[238,157,26]	-6	hSpCas9	negative selection	5346253
88760256	88760278	1	-	27760321	MOLM13	viability	GTTGCTAGTAGAACAACGAGGG	PKN2	ENSG00000065243	-1.4428332644754698	[225,186]	[26,55]	-7	hSpCas9	negative selection	5429712
88771813	88771835	1	-	27760321	MOLM13	viability	TAGATATCATACTTTGACGTGG	PKN2	ENSG00000065243	1.0724028639343837	[54,51]	[136,0]	7	hSpCas9	negative selection	5429713
88786138	88786160	1	+	27760321	MOLM13	viability	TGTGGTTGGCCAAACTAGCTGG	PKN2	ENSG00000065243	0.5972160578228737	[526,505]	[339,527]	4	hSpCas9	negative selection	5429714
88804382	88804404	1	+	27760321	MOLM13	viability	TTATCCTAGTCACGTGAACTGG	PKN2	ENSG00000065243	0.31440698948425116	[241,238]	[179,159]	2	hSpCas9	negative selection	5429715
88804470	88804492	1	+	27760321	MOLM13	viability	TTTTAGACAACCAACGGCATGG	PKN2	ENSG00000065243	-0.24087466433941374	[229,181]	[181,25]	-2	hSpCas9	negative selection	5429716
88684307	88684330	1	+	27661255	K562	viability	GGCTCCTGGCGTCGCCCAGAGGG	PKN2	ENSG00000065243	1.1164351307701086	[0,25]	[27,17]	9	dCas9-KRAB	negative selection	5502188
88684329	88684352	1	+	27661255	K562	viability	GAGCGACTAGACGAACAGTCCGG	PKN2	ENSG00000065243	0.2523307633544201	[567,625]	[694,457]	8	dCas9-KRAB	negative selection	5502189
88684338	88684361	1	+	27661255	K562	viability	GACGAACAGTCCGGTGAGGGCGG	PKN2	ENSG00000065243	0.2784271399319059	[428,539]	[467,466]	8	dCas9-KRAB	negative selection	5502190
88684613	88684636	1	+	27661255	K562	viability	GCTCACGGAACTGCAGGTAAGGG	PKN2	ENSG00000065243	0.08000351593647737	[289,241]	[274,182]	2	dCas9-KRAB	negative selection	5502191
88684372	88684395	1	-	27661255	K562	viability	GGGAGCTAGGGCACTCGTAGCGG	PKN2	ENSG00000065243	0.13834207944320054	[915,1176]	[1024,822]	5	dCas9-KRAB	negative selection	5502192
88684794	88684817	1	-	27661255	K562	viability	GGAGAGGGTCCGGCTCCCCAGGG	PKN2	ENSG00000065243	-0.11251039913826208	[654,626]	[507,444]	-4	dCas9-KRAB	negative selection	5502193
88760257	88760280	1	-	27260156	BXPC3	viability	TTGTTGCTAGTAGAACAACGAGG	PKN2	ENSG00000065243	-0.057979955393422156	[315]	[239,296,291,465]	-1	hSpCas9	negative selection	5562949
88770414	88770437	1	+	27260156	BXPC3	viability	CATACGAATGCAGATTCTTCAGG	PKN2	ENSG00000065243	0.12523325786820377	[397]	[358,496,503,461]	2	hSpCas9	negative selection	5562950
88771438	88771461	1	-	27260156	BXPC3	viability	TCTTCCATCCGAAGTTCAAGAGG	PKN2	ENSG00000065243	-0.37247785222393787	[354]	[252,227,359,315]	-7	hSpCas9	negative selection	5562951
88770363	88770386	1	-	27260156	BXPC3	viability	GCAGTTGCTGAGCTGTACCATGG	PKN2	ENSG00000065243	-0.5874500587331204	[504]	[356,330,297,425]	-8	hSpCas9	negative selection	5627201
88771430	88771453	1	+	27260156	BXPC3	viability	TGATAAGTCCTCTTGAACTTCGG	PKN2	ENSG00000065243	-0.9649107558988519	[766]	[417,403,266,567]	-9	hSpCas9	negative selection	5627202
88760268	88760291	1	+	27260156	BXPC3	viability	TACTAGCAACAATAGATTGAAGG	PKN2	ENSG00000065243	-0.6572266663610729	[119]	[84,40,130,60]	-8	hSpCas9	negative selection	5627203
88760257	88760280	1	-	27260156	A673	viability	TTGTTGCTAGTAGAACAACGAGG	PKN2	ENSG00000065243	0.22198873324351648	[315]	[522,449,437,362]	5	hSpCas9	negative selection	5684200
88770414	88770437	1	+	27260156	A673	viability	CATACGAATGCAGATTCTTCAGG	PKN2	ENSG00000065243	-0.019005746089146097	[397]	[490,437,466,493]	0	hSpCas9	negative selection	5684201
88771438	88771461	1	-	27260156	A673	viability	TCTTCCATCCGAAGTTCAAGAGG	PKN2	ENSG00000065243	0.13410999076136665	[354]	[479,431,394,571]	3	hSpCas9	negative selection	5684202
88770363	88770386	1	-	27260156	A673	viability	GCAGTTGCTGAGCTGTACCATGG	PKN2	ENSG00000065243	-0.1626846628283808	[504]	[604,573,539,447]	-4	hSpCas9	negative selection	5748452
88771430	88771453	1	+	27260156	A673	viability	TGATAAGTCCTCTTGAACTTCGG	PKN2	ENSG00000065243	-0.17037183399397637	[766]	[918,835,695,833]	-4	hSpCas9	negative selection	5748453
88760268	88760291	1	+	27260156	A673	viability	TACTAGCAACAATAGATTGAAGG	PKN2	ENSG00000065243	-0.5899976971470162	[119]	[74,137,76,88]	-8	hSpCas9	negative selection	5748454
88760257	88760280	1	-	27260156	A375	viability	TTGTTGCTAGTAGAACAACGAGG	PKN2	ENSG00000065243	0.14672711845364278	[315]	[395,410,333,482]	2	hSpCas9	negative selection	5805451
88770414	88770437	1	+	27260156	A375	viability	CATACGAATGCAGATTCTTCAGG	PKN2	ENSG00000065243	0.34238943077440215	[397]	[576,705,689,418]	5	hSpCas9	negative selection	5805452
88771438	88771461	1	-	27260156	A375	viability	TCTTCCATCCGAAGTTCAAGAGG	PKN2	ENSG00000065243	-0.29297829333295794	[354]	[331,573,268,223]	-4	hSpCas9	negative selection	5805453
88770363	88770386	1	-	27260156	A375	viability	GCAGTTGCTGAGCTGTACCATGG	PKN2	ENSG00000065243	-0.5166568039717137	[504]	[269,605,297,489]	-6	hSpCas9	negative selection	5869703
88771430	88771453	1	+	27260156	A375	viability	TGATAAGTCCTCTTGAACTTCGG	PKN2	ENSG00000065243	-0.3198512404638102	[766]	[637,863,669,715]	-4	hSpCas9	negative selection	5869704
88760268	88760291	1	+	27260156	A375	viability	TACTAGCAACAATAGATTGAAGG	PKN2	ENSG00000065243	-0.3233483212678381	[119]	[62,115,102,159]	-4	hSpCas9	negative selection	5869705
88760257	88760280	1	-	27260156	COLO741	viability	TTGTTGCTAGTAGAACAACGAGG	PKN2	ENSG00000065243	0.03258870989902063	[315]	[497,430,322]	0	hSpCas9	negative selection	5926702
88770414	88770437	1	+	27260156	COLO741	viability	CATACGAATGCAGATTCTTCAGG	PKN2	ENSG00000065243	0.12437121695178614	[397]	[495,691,474]	2	hSpCas9	negative selection	5926703
88771438	88771461	1	-	27260156	COLO741	viability	TCTTCCATCCGAAGTTCAAGAGG	PKN2	ENSG00000065243	0.4663584597901216	[354]	[628,527,714]	8	hSpCas9	negative selection	5926704
88770363	88770386	1	-	27260156	COLO741	viability	GCAGTTGCTGAGCTGTACCATGG	PKN2	ENSG00000065243	0.03835789899850307	[504]	[889,616,509]	0	hSpCas9	negative selection	5990954
88771430	88771453	1	+	27260156	COLO741	viability	TGATAAGTCCTCTTGAACTTCGG	PKN2	ENSG00000065243	-0.31097172019248537	[766]	[863,799,715]	-6	hSpCas9	negative selection	5990955
88760268	88760291	1	+	27260156	COLO741	viability	TACTAGCAACAATAGATTGAAGG	PKN2	ENSG00000065243	-0.38732068654041707	[119]	[202,86,71]	-7	hSpCas9	negative selection	5990956
88760257	88760280	1	-	27260156	CAL120	viability	TTGTTGCTAGTAGAACAACGAGG	PKN2	ENSG00000065243	-0.8540409875550217	[315]	[190,264,192]	-8	hSpCas9	negative selection	6047953
88770414	88770437	1	+	27260156	CAL120	viability	CATACGAATGCAGATTCTTCAGG	PKN2	ENSG00000065243	-0.37178282166322707	[397]	[314,500,322]	-5	hSpCas9	negative selection	6047954
88771438	88771461	1	-	27260156	CAL120	viability	TCTTCCATCCGAAGTTCAAGAGG	PKN2	ENSG00000065243	-0.7586373947331939	[354]	[270,269,243]	-8	hSpCas9	negative selection	6047955
88770363	88770386	1	-	27260156	CAL120	viability	GCAGTTGCTGAGCTGTACCATGG	PKN2	ENSG00000065243	-0.8827120145465444	[504]	[279,438,294]	-8	hSpCas9	negative selection	6112205
88771430	88771453	1	+	27260156	CAL120	viability	TGATAAGTCCTCTTGAACTTCGG	PKN2	ENSG00000065243	-1.70140152532364	[766]	[390,266,237]	-9	hSpCas9	negative selection	6112206
88760268	88760291	1	+	27260156	CAL120	viability	TACTAGCAACAATAGATTGAAGG	PKN2	ENSG00000065243	-1.868185633942361	[119]	[48,38,35]	-9	hSpCas9	negative selection	6112207
88760257	88760280	1	-	27260156	CADOES1	viability	TTGTTGCTAGTAGAACAACGAGG	PKN2	ENSG00000065243	0.31397132437436437	[315]	[408,326,339,385]	5	hSpCas9	negative selection	6169204
88770414	88770437	1	+	27260156	CADOES1	viability	CATACGAATGCAGATTCTTCAGG	PKN2	ENSG00000065243	0.46364968910411697	[397]	[361,579,700,394]	7	hSpCas9	negative selection	6169205
88771438	88771461	1	-	27260156	CADOES1	viability	TCTTCCATCCGAAGTTCAAGAGG	PKN2	ENSG00000065243	0.017208988932398916	[354]	[367,253,335,379]	0	hSpCas9	negative selection	6169206
88770363	88770386	1	-	27260156	CADOES1	viability	GCAGTTGCTGAGCTGTACCATGG	PKN2	ENSG00000065243	-0.037836305919018556	[504]	[419,498,536,370]	0	hSpCas9	negative selection	6233456
88771430	88771453	1	+	27260156	CADOES1	viability	TGATAAGTCCTCTTGAACTTCGG	PKN2	ENSG00000065243	0.13313049585045733	[766]	[983,801,479,865]	2	hSpCas9	negative selection	6233457
88760268	88760291	1	+	27260156	CADOES1	viability	TACTAGCAACAATAGATTGAAGG	PKN2	ENSG00000065243	-0.10722371996139635	[119]	[136,147,37,90]	-2	hSpCas9	negative selection	6233458
88760257	88760280	1	-	27260156	EWS502	viability	TTGTTGCTAGTAGAACAACGAGG	PKN2	ENSG00000065243	0.13623835452687844	[315]	[410,329,310,416]	2	hSpCas9	negative selection	6290455
88770414	88770437	1	+	27260156	EWS502	viability	CATACGAATGCAGATTCTTCAGG	PKN2	ENSG00000065243	0.13465988802020404	[397]	[330,496,486,555]	2	hSpCas9	negative selection	6290456
88771438	88771461	1	-	27260156	EWS502	viability	TCTTCCATCCGAAGTTCAAGAGG	PKN2	ENSG00000065243	-0.3384862814208784	[354]	[303,309,334,233]	-5	hSpCas9	negative selection	6290457
88770363	88770386	1	-	27260156	EWS502	viability	GCAGTTGCTGAGCTGTACCATGG	PKN2	ENSG00000065243	-0.29965949160398997	[504]	[401,361,546,433]	-5	hSpCas9	negative selection	6354707
88771430	88771453	1	+	27260156	EWS502	viability	TGATAAGTCCTCTTGAACTTCGG	PKN2	ENSG00000065243	-0.5268203774318788	[766]	[570,499,681,498]	-7	hSpCas9	negative selection	6354708
88760268	88760291	1	+	27260156	EWS502	viability	TACTAGCAACAATAGATTGAAGG	PKN2	ENSG00000065243	-0.5040053353401073	[119]	[31,143,97,88]	-7	hSpCas9	negative selection	6354709
88760257	88760280	1	-	27260156	EW8	viability	TTGTTGCTAGTAGAACAACGAGG	PKN2	ENSG00000065243	0.27271747354822584	[315]	[275,299,229,439]	5	hSpCas9	negative selection	6411706
88770414	88770437	1	+	27260156	EW8	viability	CATACGAATGCAGATTCTTCAGG	PKN2	ENSG00000065243	0.23025416295466536	[397]	[339,456,393,314]	4	hSpCas9	negative selection	6411707
88771438	88771461	1	-	27260156	EW8	viability	TCTTCCATCCGAAGTTCAAGAGG	PKN2	ENSG00000065243	0.4501781961937751	[354]	[363,375,504,303]	7	hSpCas9	negative selection	6411708
88770363	88770386	1	-	27260156	EW8	viability	GCAGTTGCTGAGCTGTACCATGG	PKN2	ENSG00000065243	-0.1917790109714703	[504]	[358,355,377,335]	-4	hSpCas9	negative selection	6475958
88771430	88771453	1	+	27260156	EW8	viability	TGATAAGTCCTCTTGAACTTCGG	PKN2	ENSG00000065243	-0.08694148409021452	[766]	[634,620,447,663]	-2	hSpCas9	negative selection	6475959
88760268	88760291	1	+	27260156	EW8	viability	TACTAGCAACAATAGATTGAAGG	PKN2	ENSG00000065243	-0.10579196340652453	[119]	[90,107,56,110]	-2	hSpCas9	negative selection	6475960
88760257	88760280	1	-	27260156	CORL105	viability	TTGTTGCTAGTAGAACAACGAGG	PKN2	ENSG00000065243	-0.13272756614591286	[315]	[283,238,455,388]	-2	hSpCas9	negative selection	6532957
88770414	88770437	1	+	27260156	CORL105	viability	CATACGAATGCAGATTCTTCAGG	PKN2	ENSG00000065243	0.20477831867857843	[397]	[574,569,594,417]	4	hSpCas9	negative selection	6532958
88771438	88771461	1	-	27260156	CORL105	viability	TCTTCCATCCGAAGTTCAAGAGG	PKN2	ENSG00000065243	-0.2726976329039083	[354]	[436,257,419,277]	-5	hSpCas9	negative selection	6532959
88770363	88770386	1	-	27260156	CORL105	viability	GCAGTTGCTGAGCTGTACCATGG	PKN2	ENSG00000065243	0.010042222215634139	[504]	[559,542,791,516]	0	hSpCas9	negative selection	6597209
88771430	88771453	1	+	27260156	CORL105	viability	TGATAAGTCCTCTTGAACTTCGG	PKN2	ENSG00000065243	-0.4922244331462148	[766]	[510,494,953,640]	-7	hSpCas9	negative selection	6597210
88760268	88760291	1	+	27260156	CORL105	viability	TACTAGCAACAATAGATTGAAGG	PKN2	ENSG00000065243	-0.22332416844173175	[119]	[164,60,101,152]	-4	hSpCas9	negative selection	6597211
88760257	88760280	1	-	27260156	HS294T	viability	TTGTTGCTAGTAGAACAACGAGG	PKN2	ENSG00000065243	0.04782326365231526	[315]	[51,197,90,176]	0	hSpCas9	negative selection	6654208
88770414	88770437	1	+	27260156	HS294T	viability	CATACGAATGCAGATTCTTCAGG	PKN2	ENSG00000065243	-0.14756444268983068	[397]	[140,115,128,175]	-2	hSpCas9	negative selection	6654209
88771438	88771461	1	-	27260156	HS294T	viability	TCTTCCATCCGAAGTTCAAGAGG	PKN2	ENSG00000065243	-0.5969131013971885	[354]	[87,66,101,109]	-7	hSpCas9	negative selection	6654210
88770363	88770386	1	-	27260156	HS294T	viability	GCAGTTGCTGAGCTGTACCATGG	PKN2	ENSG00000065243	0.015004089053804112	[504]	[97,269,238,186]	0	hSpCas9	negative selection	6718460
88771430	88771453	1	+	27260156	HS294T	viability	TGATAAGTCCTCTTGAACTTCGG	PKN2	ENSG00000065243	-0.5021632632470387	[766]	[255,128,165,298]	-6	hSpCas9	negative selection	6718461
88760268	88760291	1	+	27260156	HS294T	viability	TACTAGCAACAATAGATTGAAGG	PKN2	ENSG00000065243	-0.12254202619447363	[119]	[54,23,41,49]	-2	hSpCas9	negative selection	6718462
88760257	88760280	1	-	27260156	HCC44	viability	TTGTTGCTAGTAGAACAACGAGG	PKN2	ENSG00000065243	-0.09996624361213191	[315]	[424,419,362,130]	-2	hSpCas9	negative selection	6775459
88770414	88770437	1	+	27260156	HCC44	viability	CATACGAATGCAGATTCTTCAGG	PKN2	ENSG00000065243	0.0793058934136397	[397]	[417,424,716,384]	1	hSpCas9	negative selection	6775460
88771438	88771461	1	-	27260156	HCC44	viability	TCTTCCATCCGAAGTTCAAGAGG	PKN2	ENSG00000065243	-0.2521194287660478	[354]	[296,253,523,311]	-4	hSpCas9	negative selection	6775461
88770363	88770386	1	-	27260156	HCC44	viability	GCAGTTGCTGAGCTGTACCATGG	PKN2	ENSG00000065243	-0.633917301043325	[504]	[455,323,334,362]	-7	hSpCas9	negative selection	6839711
88771430	88771453	1	+	27260156	HCC44	viability	TGATAAGTCCTCTTGAACTTCGG	PKN2	ENSG00000065243	-0.6723103181248901	[766]	[631,428,725,444]	-7	hSpCas9	negative selection	6839712
88760268	88760291	1	+	27260156	HCC44	viability	TACTAGCAACAATAGATTGAAGG	PKN2	ENSG00000065243	-0.683485399935517	[119]	[77,120,90,43]	-7	hSpCas9	negative selection	6839713
88760257	88760280	1	-	27260156	G402	viability	TTGTTGCTAGTAGAACAACGAGG	PKN2	ENSG00000065243	-0.14716390619108954	[315]	[462,230,333,371]	-2	hSpCas9	negative selection	6896710
88770414	88770437	1	+	27260156	G402	viability	CATACGAATGCAGATTCTTCAGG	PKN2	ENSG00000065243	0.8173748223627104	[397]	[721,1015,649,1013]	8	hSpCas9	negative selection	6896711
88771438	88771461	1	-	27260156	G402	viability	TCTTCCATCCGAAGTTCAAGAGG	PKN2	ENSG00000065243	-0.32660062942650187	[354]	[233,329,361,432]	-4	hSpCas9	negative selection	6896712
88770363	88770386	1	-	27260156	G402	viability	GCAGTTGCTGAGCTGTACCATGG	PKN2	ENSG00000065243	-1.3673285334085907	[504]	[354,346,152,127]	-9	hSpCas9	negative selection	6960962
88771430	88771453	1	+	27260156	G402	viability	TGATAAGTCCTCTTGAACTTCGG	PKN2	ENSG00000065243	-0.7442906370222441	[766]	[720,693,588,273]	-7	hSpCas9	negative selection	6960963
88760268	88760291	1	+	27260156	G402	viability	TACTAGCAACAATAGATTGAAGG	PKN2	ENSG00000065243	-0.6377824078399714	[119]	[83,59,78,146]	-7	hSpCas9	negative selection	6960964
88760257	88760280	1	-	27260156	L33	viability	TTGTTGCTAGTAGAACAACGAGG	PKN2	ENSG00000065243	-0.3449232777655662	[315]	[351,105,123,184]	-7	hSpCas9	negative selection	7017961
88770414	88770437	1	+	27260156	L33	viability	CATACGAATGCAGATTCTTCAGG	PKN2	ENSG00000065243	0.037795752312706044	[397]	[421,188,232,379]	0	hSpCas9	negative selection	7017962
88771438	88771461	1	-	27260156	L33	viability	TCTTCCATCCGAAGTTCAAGAGG	PKN2	ENSG00000065243	0.27021915683146647	[354]	[359,141,256,596]	6	hSpCas9	negative selection	7017963
88770363	88770386	1	-	27260156	L33	viability	GCAGTTGCTGAGCTGTACCATGG	PKN2	ENSG00000065243	-0.19503547102121513	[504]	[526,127,311,426]	-4	hSpCas9	negative selection	7082213
88771430	88771453	1	+	27260156	L33	viability	TGATAAGTCCTCTTGAACTTCGG	PKN2	ENSG00000065243	-0.5100621034576496	[766]	[493,275,291,522]	-8	hSpCas9	negative selection	7082214
88760268	88760291	1	+	27260156	L33	viability	TACTAGCAACAATAGATTGAAGG	PKN2	ENSG00000065243	-0.696610420088718	[119]	[53,26,42,107]	-9	hSpCas9	negative selection	7082215
88760257	88760280	1	-	27260156	K562	viability	TTGTTGCTAGTAGAACAACGAGG	PKN2	ENSG00000065243	0.9175576973369579	[315]	[485,709,203,701]	9	hSpCas9	negative selection	7139212
88770414	88770437	1	+	27260156	K562	viability	CATACGAATGCAGATTCTTCAGG	PKN2	ENSG00000065243	0.3318016323137689	[397]	[741,314,369,374]	4	hSpCas9	negative selection	7139213
88771438	88771461	1	-	27260156	K562	viability	TCTTCCATCCGAAGTTCAAGAGG	PKN2	ENSG00000065243	0.03191558031801772	[354]	[241,384,393,268]	0	hSpCas9	negative selection	7139214
88770363	88770386	1	-	27260156	K562	viability	GCAGTTGCTGAGCTGTACCATGG	PKN2	ENSG00000065243	-0.13091588521458947	[504]	[678,185,477,313]	-2	hSpCas9	negative selection	7203464
88771430	88771453	1	+	27260156	K562	viability	TGATAAGTCCTCTTGAACTTCGG	PKN2	ENSG00000065243	0.17118249415046682	[766]	[927,618,755,764]	2	hSpCas9	negative selection	7203465
88760268	88760291	1	+	27260156	K562	viability	TACTAGCAACAATAGATTGAAGG	PKN2	ENSG00000065243	0.33627822111786543	[119]	[93,141,245,60]	4	hSpCas9	negative selection	7203466
88760257	88760280	1	-	27260156	HT29	viability	TTGTTGCTAGTAGAACAACGAGG	PKN2	ENSG00000065243	0.1256712715375528	[315]	[374,468,471,364]	2	hSpCas9	negative selection	7260463
88770414	88770437	1	+	27260156	HT29	viability	CATACGAATGCAGATTCTTCAGG	PKN2	ENSG00000065243	0.3029926951746713	[397]	[561,810,528,507]	6	hSpCas9	negative selection	7260464
88771438	88771461	1	-	27260156	HT29	viability	TCTTCCATCCGAAGTTCAAGAGG	PKN2	ENSG00000065243	-0.031900126174636445	[354]	[546,446,396,318]	0	hSpCas9	negative selection	7260465
88770363	88770386	1	-	27260156	HT29	viability	GCAGTTGCTGAGCTGTACCATGG	PKN2	ENSG00000065243	-0.6263927374236179	[504]	[374,468,384,366]	-8	hSpCas9	negative selection	7324715
88771430	88771453	1	+	27260156	HT29	viability	TGATAAGTCCTCTTGAACTTCGG	PKN2	ENSG00000065243	-0.4492327209139214	[766]	[654,825,619,640]	-7	hSpCas9	negative selection	7324716
88760268	88760291	1	+	27260156	HT29	viability	TACTAGCAACAATAGATTGAAGG	PKN2	ENSG00000065243	-0.640466722867264	[119]	[71,130,67,102]	-8	hSpCas9	negative selection	7324717
88760257	88760280	1	-	27260156	MHHES1	viability	TTGTTGCTAGTAGAACAACGAGG	PKN2	ENSG00000065243	-0.25498243139093046	[315]	[279,229,331,327]	-5	hSpCas9	negative selection	7381714
88770414	88770437	1	+	27260156	MHHES1	viability	CATACGAATGCAGATTCTTCAGG	PKN2	ENSG00000065243	0.18422646448502114	[397]	[500,649,474,430]	3	hSpCas9	negative selection	7381715
88771438	88771461	1	-	27260156	MHHES1	viability	TCTTCCATCCGAAGTTCAAGAGG	PKN2	ENSG00000065243	-0.2581787620456429	[354]	[297,452,369,238]	-5	hSpCas9	negative selection	7381716
88770363	88770386	1	-	27260156	MHHES1	viability	GCAGTTGCTGAGCTGTACCATGG	PKN2	ENSG00000065243	-0.1406263010399833	[504]	[755,588,370,398]	-3	hSpCas9	negative selection	7445966
88771430	88771453	1	+	27260156	MHHES1	viability	TGATAAGTCCTCTTGAACTTCGG	PKN2	ENSG00000065243	-0.17072414784784484	[766]	[927,654,888,622]	-3	hSpCas9	negative selection	7445967
88760268	88760291	1	+	27260156	MHHES1	viability	TACTAGCAACAATAGATTGAAGG	PKN2	ENSG00000065243	-0.5070828276014347	[119]	[40,73,139,110]	-7	hSpCas9	negative selection	7445968
88760257	88760280	1	-	27260156	MEWO	viability	TTGTTGCTAGTAGAACAACGAGG	PKN2	ENSG00000065243	-0.07318648645246295	[315]	[320,224,304]	-1	hSpCas9	negative selection	7502965
88770414	88770437	1	+	27260156	MEWO	viability	CATACGAATGCAGATTCTTCAGG	PKN2	ENSG00000065243	0.05923448959006547	[397]	[490,337,354]	1	hSpCas9	negative selection	7502966
88771438	88771461	1	-	27260156	MEWO	viability	TCTTCCATCCGAAGTTCAAGAGG	PKN2	ENSG00000065243	0.20815876691255197	[354]	[372,356,418]	4	hSpCas9	negative selection	7502967
88770363	88770386	1	-	27260156	MEWO	viability	GCAGTTGCTGAGCTGTACCATGG	PKN2	ENSG00000065243	-0.47990021910656944	[504]	[495,273,276]	-8	hSpCas9	negative selection	7567217
88771430	88771453	1	+	27260156	MEWO	viability	TGATAAGTCCTCTTGAACTTCGG	PKN2	ENSG00000065243	-0.6635557476233334	[766]	[438,502,413]	-8	hSpCas9	negative selection	7567218
88760268	88760291	1	+	27260156	MEWO	viability	TACTAGCAACAATAGATTGAAGG	PKN2	ENSG00000065243	-0.53015620722351	[119]	[71,97,61]	-8	hSpCas9	negative selection	7567219
88760257	88760280	1	-	27260156	LNCAPCLONEFGC	viability	TTGTTGCTAGTAGAACAACGAGG	PKN2	ENSG00000065243	0.26732090124015523	[315]	[379,409,284,288]	4	hSpCas9	negative selection	7624216
88770414	88770437	1	+	27260156	LNCAPCLONEFGC	viability	CATACGAATGCAGATTCTTCAGG	PKN2	ENSG00000065243	0.31863552707064086	[397]	[457,393,484,469]	5	hSpCas9	negative selection	7624217
88771438	88771461	1	-	27260156	LNCAPCLONEFGC	viability	TCTTCCATCCGAAGTTCAAGAGG	PKN2	ENSG00000065243	0.5700057342096068	[354]	[412,453,530,521]	8	hSpCas9	negative selection	7624218
88770363	88770386	1	-	27260156	LNCAPCLONEFGC	viability	GCAGTTGCTGAGCTGTACCATGG	PKN2	ENSG00000065243	0.12820353366948783	[504]	[501,428,619,470]	2	hSpCas9	negative selection	7688468
88771430	88771453	1	+	27260156	LNCAPCLONEFGC	viability	TGATAAGTCCTCTTGAACTTCGG	PKN2	ENSG00000065243	0.11154929694203286	[766]	[765,740,875,637]	1	hSpCas9	negative selection	7688469
88760268	88760291	1	+	27260156	LNCAPCLONEFGC	viability	TACTAGCAACAATAGATTGAAGG	PKN2	ENSG00000065243	0.003331674215133029	[119]	[58,97,105,173]	0	hSpCas9	negative selection	7688470
88760257	88760280	1	-	27260156	PANC0327	viability	TTGTTGCTAGTAGAACAACGAGG	PKN2	ENSG00000065243	-0.3293764091117012	[315]	[185,233,174,293]	-5	hSpCas9	negative selection	7745467
88770414	88770437	1	+	27260156	PANC0327	viability	CATACGAATGCAGATTCTTCAGG	PKN2	ENSG00000065243	0.28192383960158435	[397]	[412,387,328,592]	4	hSpCas9	negative selection	7745468
88771438	88771461	1	-	27260156	PANC0327	viability	TCTTCCATCCGAAGTTCAAGAGG	PKN2	ENSG00000065243	-1.2437191469915672	[354]	[199,63,122,159]	-9	hSpCas9	negative selection	7745469
88770363	88770386	1	-	27260156	PANC0327	viability	GCAGTTGCTGAGCTGTACCATGG	PKN2	ENSG00000065243	-0.6891061090301478	[504]	[247,318,222,314]	-7	hSpCas9	negative selection	7809719
88771430	88771453	1	+	27260156	PANC0327	viability	TGATAAGTCCTCTTGAACTTCGG	PKN2	ENSG00000065243	-1.3945769504683145	[766]	[140,273,321,287]	-9	hSpCas9	negative selection	7809720
88760268	88760291	1	+	27260156	PANC0327	viability	TACTAGCAACAATAGATTGAAGG	PKN2	ENSG00000065243	-0.7177763575247418	[119]	[41,67,87,58]	-7	hSpCas9	negative selection	7809721
88760257	88760280	1	-	27260156	NCIH2009	viability	TTGTTGCTAGTAGAACAACGAGG	PKN2	ENSG00000065243	-0.7933028353173117	[315]	[225,207,324]	-7	hSpCas9	negative selection	7866718
88770414	88770437	1	+	27260156	NCIH2009	viability	CATACGAATGCAGATTCTTCAGG	PKN2	ENSG00000065243	0.07690276347633793	[397]	[570,667,514]	1	hSpCas9	negative selection	7866719
88771438	88771461	1	-	27260156	NCIH2009	viability	TCTTCCATCCGAAGTTCAAGAGG	PKN2	ENSG00000065243	-0.5472281601356375	[354]	[507,229,314]	-6	hSpCas9	negative selection	7866720
88770363	88770386	1	-	27260156	NCIH2009	viability	GCAGTTGCTGAGCTGTACCATGG	PKN2	ENSG00000065243	-0.8877587992289045	[504]	[485,271,407]	-8	hSpCas9	negative selection	7930970
88771430	88771453	1	+	27260156	NCIH2009	viability	TGATAAGTCCTCTTGAACTTCGG	PKN2	ENSG00000065243	-1.23455077048428	[766]	[432,401,526]	-8	hSpCas9	negative selection	7930971
88760268	88760291	1	+	27260156	NCIH2009	viability	TACTAGCAACAATAGATTGAAGG	PKN2	ENSG00000065243	-0.8410959841987211	[119]	[114,84,84]	-7	hSpCas9	negative selection	7930972
88760257	88760280	1	-	27260156	NCIH1373	viability	TTGTTGCTAGTAGAACAACGAGG	PKN2	ENSG00000065243	-0.7129650003409906	[315]	[183,189,149,90]	-6	hSpCas9	negative selection	7987969
88770414	88770437	1	+	27260156	NCIH1373	viability	CATACGAATGCAGATTCTTCAGG	PKN2	ENSG00000065243	1.064369807388025	[397]	[1676,1200,326,157]	9	hSpCas9	negative selection	7987970
88771438	88771461	1	-	27260156	NCIH1373	viability	TCTTCCATCCGAAGTTCAAGAGG	PKN2	ENSG00000065243	-1.7970740365750426	[354]	[124,108,93,34]	-9	hSpCas9	negative selection	7987971
88770363	88770386	1	-	27260156	NCIH1373	viability	GCAGTTGCTGAGCTGTACCATGG	PKN2	ENSG00000065243	-0.7922689711847906	[504]	[478,330,232,74]	-7	hSpCas9	negative selection	8052221
88771430	88771453	1	+	27260156	NCIH1373	viability	TGATAAGTCCTCTTGAACTTCGG	PKN2	ENSG00000065243	-0.8526573903542745	[766]	[313,433,516,163]	-7	hSpCas9	negative selection	8052222
88760268	88760291	1	+	27260156	NCIH1373	viability	TACTAGCAACAATAGATTGAAGG	PKN2	ENSG00000065243	-1.0328152221910745	[119]	[186,23,35,9]	-8	hSpCas9	negative selection	8052223
88760257	88760280	1	-	27260156	PATU8902	viability	TTGTTGCTAGTAGAACAACGAGG	PKN2	ENSG00000065243	0.4705410841425902	[315]	[255,1045,482,698]	5	hSpCas9	negative selection	8109220
88770414	88770437	1	+	27260156	PATU8902	viability	CATACGAATGCAGATTCTTCAGG	PKN2	ENSG00000065243	1.0333836732558952	[397]	[1185,934,782,1793]	9	hSpCas9	negative selection	8109221
88771438	88771461	1	-	27260156	PATU8902	viability	TCTTCCATCCGAAGTTCAAGAGG	PKN2	ENSG00000065243	0.34955576312634845	[354]	[1339,426,306,498]	3	hSpCas9	negative selection	8109222
88770363	88770386	1	-	27260156	PATU8902	viability	GCAGTTGCTGAGCTGTACCATGG	PKN2	ENSG00000065243	-0.2920811427367829	[504]	[425,668,312,1006]	-3	hSpCas9	negative selection	8173472
88771430	88771453	1	+	27260156	PATU8902	viability	TGATAAGTCCTCTTGAACTTCGG	PKN2	ENSG00000065243	0.06151946790434659	[766]	[1370,1049,816,1308]	0	hSpCas9	negative selection	8173473
88760268	88760291	1	+	27260156	PATU8902	viability	TACTAGCAACAATAGATTGAAGG	PKN2	ENSG00000065243	0.06326891751252184	[119]	[393,18,186,78]	0	hSpCas9	negative selection	8173474
88760257	88760280	1	-	27260156	PANC1	viability	TTGTTGCTAGTAGAACAACGAGG	PKN2	ENSG00000065243	-0.4096405957673447	[315]	[202,395,147,119]	-6	hSpCas9	negative selection	8230471
88770414	88770437	1	+	27260156	PANC1	viability	CATACGAATGCAGATTCTTCAGG	PKN2	ENSG00000065243	0.29509201984508826	[397]	[494,610,323,297]	5	hSpCas9	negative selection	8230472
88771438	88771461	1	-	27260156	PANC1	viability	TCTTCCATCCGAAGTTCAAGAGG	PKN2	ENSG00000065243	-0.8957462394138014	[354]	[152,232,104,173]	-8	hSpCas9	negative selection	8230473
88770363	88770386	1	-	27260156	PANC1	viability	GCAGTTGCTGAGCTGTACCATGG	PKN2	ENSG00000065243	-0.67078063924156	[504]	[308,326,318,159]	-7	hSpCas9	negative selection	8294723
88771430	88771453	1	+	27260156	PANC1	viability	TGATAAGTCCTCTTGAACTTCGG	PKN2	ENSG00000065243	-0.994088262627892	[766]	[269,343,397,312]	-8	hSpCas9	negative selection	8294724
88760268	88760291	1	+	27260156	PANC1	viability	TACTAGCAACAATAGATTGAAGG	PKN2	ENSG00000065243	-1.084941787440943	[119]	[25,28,77,55]	-8	hSpCas9	negative selection	8294725
88760257	88760280	1	-	27260156	PANC0813	viability	TTGTTGCTAGTAGAACAACGAGG	PKN2	ENSG00000065243	-0.3267484395736201	[315]	[347,228,378,235]	-5	hSpCas9	negative selection	8351722
88770414	88770437	1	+	27260156	PANC0813	viability	CATACGAATGCAGATTCTTCAGG	PKN2	ENSG00000065243	0.2480397359155869	[397]	[541,672,411,588]	4	hSpCas9	negative selection	8351723
88771438	88771461	1	-	27260156	PANC0813	viability	TCTTCCATCCGAAGTTCAAGAGG	PKN2	ENSG00000065243	-0.2935802447517661	[354]	[369,339,313,338]	-5	hSpCas9	negative selection	8351724
88770363	88770386	1	-	27260156	PANC0813	viability	GCAGTTGCTGAGCTGTACCATGG	PKN2	ENSG00000065243	-0.5612427147586415	[504]	[387,439,410,368]	-7	hSpCas9	negative selection	8415974
88771430	88771453	1	+	27260156	PANC0813	viability	TGATAAGTCCTCTTGAACTTCGG	PKN2	ENSG00000065243	-0.41420186287964345	[766]	[767,603,598,736]	-6	hSpCas9	negative selection	8415975
88760268	88760291	1	+	27260156	PANC0813	viability	TACTAGCAACAATAGATTGAAGG	PKN2	ENSG00000065243	0.14269601712595814	[119]	[100,168,134,208]	2	hSpCas9	negative selection	8415976
88760257	88760280	1	-	27260156	RDES	viability	TTGTTGCTAGTAGAACAACGAGG	PKN2	ENSG00000065243	0.39060893826965615	[315]	[532,381,412,568]	6	hSpCas9	negative selection	8472973
88770414	88770437	1	+	27260156	RDES	viability	CATACGAATGCAGATTCTTCAGG	PKN2	ENSG00000065243	0.6526771233039816	[397]	[482,889,618,927]	9	hSpCas9	negative selection	8472974
88771438	88771461	1	-	27260156	RDES	viability	TCTTCCATCCGAAGTTCAAGAGG	PKN2	ENSG00000065243	0.10250007682449797	[354]	[376,346,483,576]	1	hSpCas9	negative selection	8472975
88770363	88770386	1	-	27260156	RDES	viability	GCAGTTGCTGAGCTGTACCATGG	PKN2	ENSG00000065243	-0.07850661844654594	[504]	[480,521,576,633]	-1	hSpCas9	negative selection	8537225
88771430	88771453	1	+	27260156	RDES	viability	TGATAAGTCCTCTTGAACTTCGG	PKN2	ENSG00000065243	-0.4356685232078828	[766]	[555,585,609,899]	-6	hSpCas9	negative selection	8537226
88760268	88760291	1	+	27260156	RDES	viability	TACTAGCAACAATAGATTGAAGG	PKN2	ENSG00000065243	-0.16987061307904727	[119]	[96,103,101,202]	-3	hSpCas9	negative selection	8537227
88760257	88760280	1	-	27260156	PC3	viability	TTGTTGCTAGTAGAACAACGAGG	PKN2	ENSG00000065243	-0.2228843468583901	[315]	[137,265,516,291]	-5	hSpCas9	negative selection	8594224
88770414	88770437	1	+	27260156	PC3	viability	CATACGAATGCAGATTCTTCAGG	PKN2	ENSG00000065243	0.1121142147926755	[397]	[239,400,570,612]	2	hSpCas9	negative selection	8594225
88771438	88771461	1	-	27260156	PC3	viability	TCTTCCATCCGAAGTTCAAGAGG	PKN2	ENSG00000065243	0.12496289264407878	[354]	[178,370,644,517]	3	hSpCas9	negative selection	8594226
88770363	88770386	1	-	27260156	PC3	viability	GCAGTTGCTGAGCTGTACCATGG	PKN2	ENSG00000065243	-0.5485109387313853	[504]	[162,362,544,439]	-8	hSpCas9	negative selection	8658476
88771430	88771453	1	+	27260156	PC3	viability	TGATAAGTCCTCTTGAACTTCGG	PKN2	ENSG00000065243	-0.7233826613558489	[766]	[269,556,765,410]	-9	hSpCas9	negative selection	8658477
88760268	88760291	1	+	27260156	PC3	viability	TACTAGCAACAATAGATTGAAGG	PKN2	ENSG00000065243	-0.025667625620567458	[119]	[38,160,203,124]	0	hSpCas9	negative selection	8658478
88760257	88760280	1	-	27260156	PATU8988T	viability	TTGTTGCTAGTAGAACAACGAGG	PKN2	ENSG00000065243	0.05476742921769806	[315]	[307,265,303,391]	0	hSpCas9	negative selection	8715475
88770414	88770437	1	+	27260156	PATU8988T	viability	CATACGAATGCAGATTCTTCAGG	PKN2	ENSG00000065243	0.29239624321687907	[397]	[423,330,616,498]	5	hSpCas9	negative selection	8715476
88771438	88771461	1	-	27260156	PATU8988T	viability	TCTTCCATCCGAAGTTCAAGAGG	PKN2	ENSG00000065243	-0.34099030942591885	[354]	[331,284,232,231]	-5	hSpCas9	negative selection	8715477
88770363	88770386	1	-	27260156	PATU8988T	viability	GCAGTTGCTGAGCTGTACCATGG	PKN2	ENSG00000065243	-0.2636130017232923	[504]	[238,558,422,419]	-4	hSpCas9	negative selection	8779727
88771430	88771453	1	+	27260156	PATU8988T	viability	TGATAAGTCCTCTTGAACTTCGG	PKN2	ENSG00000065243	-0.6195215135323882	[766]	[297,567,519,556]	-7	hSpCas9	negative selection	8779728
88760268	88760291	1	+	27260156	PATU8988T	viability	TACTAGCAACAATAGATTGAAGG	PKN2	ENSG00000065243	0.263571774685039	[119]	[58,310,43,161]	4	hSpCas9	negative selection	8779729
88760257	88760280	1	-	27260156	T47D	viability	TTGTTGCTAGTAGAACAACGAGG	PKN2	ENSG00000065243	0.2575873115714199	[315]	[435,326,546,458]	5	hSpCas9	negative selection	8836726
88770414	88770437	1	+	27260156	T47D	viability	CATACGAATGCAGATTCTTCAGG	PKN2	ENSG00000065243	0.1941381305361774	[397]	[605,423,500,602]	4	hSpCas9	negative selection	8836727
88771438	88771461	1	-	27260156	T47D	viability	TCTTCCATCCGAAGTTCAAGAGG	PKN2	ENSG00000065243	0.11256923438397837	[354]	[392,462,486,442]	2	hSpCas9	negative selection	8836728
88770363	88770386	1	-	27260156	T47D	viability	GCAGTTGCTGAGCTGTACCATGG	PKN2	ENSG00000065243	-0.35331531209112543	[504]	[457,364,475,553]	-6	hSpCas9	negative selection	8900978
88771430	88771453	1	+	27260156	T47D	viability	TGATAAGTCCTCTTGAACTTCGG	PKN2	ENSG00000065243	-0.37623759188486017	[766]	[769,652,616,718]	-7	hSpCas9	negative selection	8900979
88760268	88760291	1	+	27260156	T47D	viability	TACTAGCAACAATAGATTGAAGG	PKN2	ENSG00000065243	-0.06307018712272394	[119]	[164,120,131,117]	-1	hSpCas9	negative selection	8900980
88760257	88760280	1	-	27260156	SU8686	viability	TTGTTGCTAGTAGAACAACGAGG	PKN2	ENSG00000065243	-0.45617528840900534	[315]	[187,165,287,294]	-6	hSpCas9	negative selection	8957977
88770414	88770437	1	+	27260156	SU8686	viability	CATACGAATGCAGATTCTTCAGG	PKN2	ENSG00000065243	0.36423191614978684	[397]	[410,403,560,710]	6	hSpCas9	negative selection	8957978
88771438	88771461	1	-	27260156	SU8686	viability	TCTTCCATCCGAAGTTCAAGAGG	PKN2	ENSG00000065243	-0.9514181393293775	[354]	[145,144,251,196]	-8	hSpCas9	negative selection	8957979
88770363	88770386	1	-	27260156	SU8686	viability	GCAGTTGCTGAGCTGTACCATGG	PKN2	ENSG00000065243	-0.3537498892377616	[504]	[352,352,323,570]	-5	hSpCas9	negative selection	9022229
88771430	88771453	1	+	27260156	SU8686	viability	TGATAAGTCCTCTTGAACTTCGG	PKN2	ENSG00000065243	-0.9387635061393513	[766]	[389,356,460,380]	-8	hSpCas9	negative selection	9022230
88760268	88760291	1	+	27260156	SU8686	viability	TACTAGCAACAATAGATTGAAGG	PKN2	ENSG00000065243	-0.38861228655379176	[119]	[128,48,138,39]	-6	hSpCas9	negative selection	9022231
88760257	88760280	1	-	27260156	SKES1	viability	TTGTTGCTAGTAGAACAACGAGG	PKN2	ENSG00000065243	0.28297212348094525	[315]	[523,341,392,295]	6	hSpCas9	negative selection	9079228
88770414	88770437	1	+	27260156	SKES1	viability	CATACGAATGCAGATTCTTCAGG	PKN2	ENSG00000065243	0.11414815626772648	[397]	[419,478,438,385]	2	hSpCas9	negative selection	9079229
88771438	88771461	1	-	27260156	SKES1	viability	TCTTCCATCCGAAGTTCAAGAGG	PKN2	ENSG00000065243	0.6497535967247425	[354]	[589,467,553,593]	9	hSpCas9	negative selection	9079230
88770363	88770386	1	-	27260156	SKES1	viability	GCAGTTGCTGAGCTGTACCATGG	PKN2	ENSG00000065243	-0.06754786354268714	[504]	[650,692,308,333]	-1	hSpCas9	negative selection	9143480
88771430	88771453	1	+	27260156	SKES1	viability	TGATAAGTCCTCTTGAACTTCGG	PKN2	ENSG00000065243	-0.07501563166650571	[766]	[804,676,704,716]	-2	hSpCas9	negative selection	9143481
88760268	88760291	1	+	27260156	SKES1	viability	TACTAGCAACAATAGATTGAAGG	PKN2	ENSG00000065243	-0.0952303142660933	[119]	[77,141,114,110]	-2	hSpCas9	negative selection	9143482
88760257	88760280	1	-	27260156	TOV112D	viability	TTGTTGCTAGTAGAACAACGAGG	PKN2	ENSG00000065243	-0.05901287217922968	[315]	[181,292,393,331]	-1	hSpCas9	negative selection	9200479
88770414	88770437	1	+	27260156	TOV112D	viability	CATACGAATGCAGATTCTTCAGG	PKN2	ENSG00000065243	0.4737378655866354	[397]	[550,942,371,445]	8	hSpCas9	negative selection	9200480
88771438	88771461	1	-	27260156	TOV112D	viability	TCTTCCATCCGAAGTTCAAGAGG	PKN2	ENSG00000065243	0.17363334749036266	[354]	[329,448,419,409]	3	hSpCas9	negative selection	9200481
88770363	88770386	1	-	27260156	TOV112D	viability	GCAGTTGCTGAGCTGTACCATGG	PKN2	ENSG00000065243	-0.36474669244397306	[504]	[454,414,273,435]	-6	hSpCas9	negative selection	9264731
88771430	88771453	1	+	27260156	TOV112D	viability	TGATAAGTCCTCTTGAACTTCGG	PKN2	ENSG00000065243	-0.772055970746793	[766]	[509,371,433,467]	-9	hSpCas9	negative selection	9264732
88760268	88760291	1	+	27260156	TOV112D	viability	TACTAGCAACAATAGATTGAAGG	PKN2	ENSG00000065243	-0.48771665648012674	[119]	[49,101,152,39]	-7	hSpCas9	negative selection	9264733
88760257	88760280	1	-	27260156	TC71	viability	TTGTTGCTAGTAGAACAACGAGG	PKN2	ENSG00000065243	0.2663124969931249	[315]	[501,439,277,411]	6	hSpCas9	negative selection	9321730
88770414	88770437	1	+	27260156	TC71	viability	CATACGAATGCAGATTCTTCAGG	PKN2	ENSG00000065243	0.19247910002990137	[397]	[588,431,433,494]	5	hSpCas9	negative selection	9321731
88771438	88771461	1	-	27260156	TC71	viability	TCTTCCATCCGAAGTTCAAGAGG	PKN2	ENSG00000065243	0.19531713048884794	[354]	[294,483,556,403]	5	hSpCas9	negative selection	9321732
88770363	88770386	1	-	27260156	TC71	viability	GCAGTTGCTGAGCTGTACCATGG	PKN2	ENSG00000065243	-0.07238632511471801	[504]	[368,496,519,686]	-2	hSpCas9	negative selection	9385982
88771430	88771453	1	+	27260156	TC71	viability	TGATAAGTCCTCTTGAACTTCGG	PKN2	ENSG00000065243	-0.22308081812652925	[766]	[568,815,716,718]	-5	hSpCas9	negative selection	9385983
88760268	88760291	1	+	27260156	TC71	viability	TACTAGCAACAATAGATTGAAGG	PKN2	ENSG00000065243	-0.0017442029613308208	[119]	[111,163,108,129]	0	hSpCas9	negative selection	9385984
88760257	88760280	1	-	27260156	TC32	viability	TTGTTGCTAGTAGAACAACGAGG	PKN2	ENSG00000065243	0.15790773763077764	[315]	[279,218,561,334]	3	hSpCas9	negative selection	9442981
88770414	88770437	1	+	27260156	TC32	viability	CATACGAATGCAGATTCTTCAGG	PKN2	ENSG00000065243	0.44791602632360966	[397]	[358,627,513,477]	7	hSpCas9	negative selection	9442982
88771438	88771461	1	-	27260156	TC32	viability	TCTTCCATCCGAAGTTCAAGAGG	PKN2	ENSG00000065243	0.5739011823204859	[354]	[408,504,478,569]	8	hSpCas9	negative selection	9442983
88770363	88770386	1	-	27260156	TC32	viability	GCAGTTGCTGAGCTGTACCATGG	PKN2	ENSG00000065243	0.06925089451325074	[504]	[466,324,609,658]	1	hSpCas9	negative selection	9507233
88771430	88771453	1	+	27260156	TC32	viability	TGATAAGTCCTCTTGAACTTCGG	PKN2	ENSG00000065243	-0.18080786178477504	[766]	[772,345,835,680]	-3	hSpCas9	negative selection	9507234
88760268	88760291	1	+	27260156	TC32	viability	TACTAGCAACAATAGATTGAAGG	PKN2	ENSG00000065243	-0.0290290890842122	[119]	[135,82,91,128]	0	hSpCas9	negative selection	9507235
88684562	88684585	1	+	27869803	HPAFII	viability after 27 days	GAGTCCATACCGGAGCGCAATGG	PKN2	ENSG00000065243	-1.2834400928979828	[156]	[52,17,NaN]	-7	hSpCas9	negative selection	9535841
88770363	88770386	1	-	27869803	HPAFII	viability after 27 days	GCAGTTGCTGAGCTGTACCATGG	PKN2	ENSG00000065243	-3.669354688011529	[428]	[20,14,NaN]	-9	hSpCas9	negative selection	9535843
88786186	88786209	1	+	27869803	HPAFII	viability after 27 days	CCAGAAGTTTACACTGGAACTGG	PKN2	ENSG00000065243	0.39644948185794515	[543]	[556,225,NaN]	3	hSpCas9	negative selection	9535845
88805628	88805651	1	-	27869803	HPAFII	viability after 27 days	GGGATGCGTACATCAACCACTGG	PKN2	ENSG00000065243	-4.352030126676782	[112]	[3,1,NaN]	-9	hSpCas9	negative selection	9535847
88807754	88807777	1	+	27869803	HPAFII	viability after 27 days	TGGCTCGAGATGAAGTAGACAGG	PKN2	ENSG00000065243	-1.2142545610629718	[466]	[83,123,NaN]	-7	hSpCas9	negative selection	9535850
88832753	88832776	1	-	27869803	HPAFII	viability after 27 days	ACTTCCTCTTCATCATCACCAGG	PKN2	ENSG00000065243	-2.8119590834543287	[67]	[3,5,NaN]	-9	hSpCas9	negative selection	9535851
88684562	88684585	1	+	27869803	HPAFII	viability after 15 days	GAGTCCATACCGGAGCGCAATGG	PKN2	ENSG00000065243	-0.4032823171639608	[156]	[142,117,NaN]	-4	hSpCas9	negative selection	9618290
88770363	88770386	1	-	27869803	HPAFII	viability after 15 days	GCAGTTGCTGAGCTGTACCATGG	PKN2	ENSG00000065243	-1.5422552522532675	[428]	[198,132,NaN]	-8	hSpCas9	negative selection	9618292
88786186	88786209	1	+	27869803	HPAFII	viability after 15 days	CCAGAAGTTTACACTGGAACTGG	PKN2	ENSG00000065243	0.33756911975034454	[543]	[1080,525,NaN]	4	hSpCas9	negative selection	9618294
88805628	88805651	1	-	27869803	HPAFII	viability after 15 days	GGGATGCGTACATCAACCACTGG	PKN2	ENSG00000065243	-2.8682193513119842	[112]	[7,21,NaN]	-9	hSpCas9	negative selection	9618296
88807754	88807777	1	+	27869803	HPAFII	viability after 15 days	TGGCTCGAGATGAAGTAGACAGG	PKN2	ENSG00000065243	-0.3654594222737457	[466]	[404,379,NaN]	-4	hSpCas9	negative selection	9618299
88832753	88832776	1	-	27869803	HPAFII	viability after 15 days	ACTTCCTCTTCATCATCACCAGG	PKN2	ENSG00000065243	-1.0048284994139292	[67]	[57,22,NaN]	-7	hSpCas9	negative selection	9618300
88684562	88684585	1	+	27869803	ASPC1	viability after 36 days	GAGTCCATACCGGAGCGCAATGG	PKN2	ENSG00000065243	0.3516720037356404	[449]	[473,40,132]	3	hSpCas9	negative selection	9700739
88770363	88770386	1	-	27869803	ASPC1	viability after 36 days	GCAGTTGCTGAGCTGTACCATGG	PKN2	ENSG00000065243	-0.5756591143962798	[895]	[217,268,154]	-5	hSpCas9	negative selection	9700741
88786186	88786209	1	+	27869803	ASPC1	viability after 36 days	CCAGAAGTTTACACTGGAACTGG	PKN2	ENSG00000065243	0.34156374922118893	[1606]	[872,514,744]	3	hSpCas9	negative selection	9700743
88805628	88805651	1	-	27869803	ASPC1	viability after 36 days	GGGATGCGTACATCAACCACTGG	PKN2	ENSG00000065243	-0.2981767186387623	[201]	[168,9,15]	-3	hSpCas9	negative selection	9700745
88807754	88807777	1	+	27869803	ASPC1	viability after 36 days	TGGCTCGAGATGAAGTAGACAGG	PKN2	ENSG00000065243	0.7340157396970409	[659]	[416,413,330]	7	hSpCas9	negative selection	9700748
88832753	88832776	1	-	27869803	ASPC1	viability after 36 days	ACTTCCTCTTCATCATCACCAGG	PKN2	ENSG00000065243	0.6219346412470559	[191]	[165,155,15]	6	hSpCas9	negative selection	9700749
88684562	88684585	1	+	27869803	PATU8988S	viability after 35 days	GAGTCCATACCGGAGCGCAATGG	PKN2	ENSG00000065243	0.5697557675849274	[343]	[266,143,NaN]	6	hSpCas9	negative selection	9783188
88770363	88770386	1	-	27869803	PATU8988S	viability after 35 days	GCAGTTGCTGAGCTGTACCATGG	PKN2	ENSG00000065243	0.8483875041287684	[880]	[574,702,NaN]	8	hSpCas9	negative selection	9783190
88786186	88786209	1	+	27869803	PATU8988S	viability after 35 days	CCAGAAGTTTACACTGGAACTGG	PKN2	ENSG00000065243	0.18583819061324647	[1555]	[639,785,NaN]	2	hSpCas9	negative selection	9783192
88805628	88805651	1	-	27869803	PATU8988S	viability after 35 days	GGGATGCGTACATCAACCACTGG	PKN2	ENSG00000065243	0.3370583738560926	[226]	[108,121,NaN]	4	hSpCas9	negative selection	9783194
88807754	88807777	1	+	27869803	PATU8988S	viability after 35 days	TGGCTCGAGATGAAGTAGACAGG	PKN2	ENSG00000065243	0.7603739357467394	[616]	[392,448,NaN]	7	hSpCas9	negative selection	9783197
88832753	88832776	1	-	27869803	PATU8988S	viability after 35 days	ACTTCCTCTTCATCATCACCAGG	PKN2	ENSG00000065243	0.9308745100129004	[182]	[144,135,NaN]	8	hSpCas9	negative selection	9783198
88684562	88684585	1	+	27869803	PATU8988S	viability after 31 days	GAGTCCATACCGGAGCGCAATGG	PKN2	ENSG00000065243	0.7356871624076446	[343]	[278,163,NaN]	8	hSpCas9	negative selection	9865637
88770363	88770386	1	-	27869803	PATU8988S	viability after 31 days	GCAGTTGCTGAGCTGTACCATGG	PKN2	ENSG00000065243	0.8998735401269625	[880]	[453,911,NaN]	8	hSpCas9	negative selection	9865639
88786186	88786209	1	+	27869803	PATU8988S	viability after 31 days	CCAGAAGTTTACACTGGAACTGG	PKN2	ENSG00000065243	0.143502894936534	[1555]	[555,849,NaN]	1	hSpCas9	negative selection	9865641
88805628	88805651	1	-	27869803	PATU8988S	viability after 31 days	GGGATGCGTACATCAACCACTGG	PKN2	ENSG00000065243	0.3412494876602049	[226]	[60,182,NaN]	4	hSpCas9	negative selection	9865643
88807754	88807777	1	+	27869803	PATU8988S	viability after 31 days	TGGCTCGAGATGAAGTAGACAGG	PKN2	ENSG00000065243	0.673918527658893	[616]	[333,466,NaN]	7	hSpCas9	negative selection	9865646
88832753	88832776	1	-	27869803	PATU8988S	viability after 31 days	ACTTCCTCTTCATCATCACCAGG	PKN2	ENSG00000065243	0.8268302219715665	[182]	[95,171,NaN]	8	hSpCas9	negative selection	9865647
88684562	88684585	1	+	27869803	HPAFII	viability after 35 days	GAGTCCATACCGGAGCGCAATGG	PKN2	ENSG00000065243	-0.9544239714951777	[156]	[72,4,NaN]	-5	hSpCas9	negative selection	9948086
88770363	88770386	1	-	27869803	HPAFII	viability after 35 days	GCAGTTGCTGAGCTGTACCATGG	PKN2	ENSG00000065243	-4.334227871185109	[428]	[14,5,NaN]	-9	hSpCas9	negative selection	9948088
88786186	88786209	1	+	27869803	HPAFII	viability after 35 days	CCAGAAGTTTACACTGGAACTGG	PKN2	ENSG00000065243	0.09782377232024397	[543]	[440,129,NaN]	0	hSpCas9	negative selection	9948090
88805628	88805651	1	-	27869803	HPAFII	viability after 35 days	GGGATGCGTACATCAACCACTGG	PKN2	ENSG00000065243	-5.838090409418513	[112]	[0,0,NaN]	-9	hSpCas9	negative selection	9948092
88807754	88807777	1	+	27869803	HPAFII	viability after 35 days	TGGCTCGAGATGAAGTAGACAGG	PKN2	ENSG00000065243	-1.0667785215256487	[466]	[70,159,NaN]	-6	hSpCas9	negative selection	9948095
88832753	88832776	1	-	27869803	HPAFII	viability after 35 days	ACTTCCTCTTCATCATCACCAGG	PKN2	ENSG00000065243	-1.366841398940498	[67]	[2,24,NaN]	-6	hSpCas9	negative selection	9948096
88684562	88684585	1	+	27869803	HPAFII	viability after 31 days	GAGTCCATACCGGAGCGCAATGG	PKN2	ENSG00000065243	-1.4895417820685743	[156]	[50,9,NaN]	-7	hSpCas9	negative selection	10030535
88770363	88770386	1	-	27869803	HPAFII	viability after 31 days	GCAGTTGCTGAGCTGTACCATGG	PKN2	ENSG00000065243	-4.504498439081126	[428]	[12,7,NaN]	-9	hSpCas9	negative selection	10030537
88786186	88786209	1	+	27869803	HPAFII	viability after 31 days	CCAGAAGTTTACACTGGAACTGG	PKN2	ENSG00000065243	0.31220708476605075	[543]	[614,121,NaN]	2	hSpCas9	negative selection	10030539
88805628	88805651	1	-	27869803	HPAFII	viability after 31 days	GGGATGCGTACATCAACCACTGG	PKN2	ENSG00000065243	-5.9868077627399305	[112]	[0,0,NaN]	-9	hSpCas9	negative selection	10030541
88807754	88807777	1	+	27869803	HPAFII	viability after 31 days	TGGCTCGAGATGAAGTAGACAGG	PKN2	ENSG00000065243	-1.2474978743639666	[466]	[118,100,NaN]	-6	hSpCas9	negative selection	10030544
88832753	88832776	1	-	27869803	HPAFII	viability after 31 days	ACTTCCTCTTCATCATCACCAGG	PKN2	ENSG00000065243	-2.5679913627065094	[67]	[4,7,NaN]	-8	hSpCas9	negative selection	10030545
88770363	88770386	1	-	28162770	P31FUJ	viability	GCAGTTGCTGAGCTGTACCATGG	PKN2	ENSG00000065243	0.7491551982037397	[522]	[1032]	8	hSpCas9	negative selection	10211961
88684607	88684630	1	+	28162770	P31FUJ	viability	GATTCTGCTCACGGAACTGCAGG	PKN2	ENSG00000065243	0.06560653152130032	[234]	[288]	0	hSpCas9	negative selection	10211962
88805937	88805960	1	-	28162770	P31FUJ	viability	GAAGCTCGTGGTGGGGCTGGAGG	PKN2	ENSG00000065243	-0.12115684858546927	[86]	[93]	-1	hSpCas9	negative selection	10211963
88771434	88771457	1	+	28162770	P31FUJ	viability	AAGTCCTCTTGAACTTCGGATGG	PKN2	ENSG00000065243	0.9934736514092977	[52]	[123]	9	hSpCas9	negative selection	10211964
88804511	88804534	1	-	28162770	P31FUJ	viability	TCTGCAAATAAAGTACCCTGTGG	PKN2	ENSG00000065243	0.8388992609398103	[156]	[329]	8	hSpCas9	negative selection	10211965
88805628	88805651	1	-	28162770	P31FUJ	viability	GGGATGCGTACATCAACCACTGG	PKN2	ENSG00000065243	0.25443667454219754	[340]	[477]	2	hSpCas9	negative selection	10211966
88805661	88805684	1	-	28162770	P31FUJ	viability	TCAGACACATACCTAGCTGGAGG	PKN2	ENSG00000065243	0.2453535697797592	[340]	[474]	2	hSpCas9	negative selection	10211967
88813660	88813683	1	+	28162770	P31FUJ	viability	GTAATGGAATATGCTGCCGGTGG	PKN2	ENSG00000065243	-0.5409244997767102	[25]	[20]	-4	hSpCas9	negative selection	10211968
88833109	88833132	1	+	28162770	P31FUJ	viability	GGCTAGCGAGAAAGATGCAGAGG	PKN2	ENSG00000065243	0.5498409641464718	[285]	[491]	6	hSpCas9	negative selection	10211969
88684581	88684604	1	+	28162770	P31FUJ	viability	ATGGCGTCCAACCCCGAACGGGG	PKN2	ENSG00000065243	0.11600159646437846	[116]	[148]	1	hSpCas9	negative selection	10211970
88770363	88770386	1	-	28162770	TF1	viability	GCAGTTGCTGAGCTGTACCATGG	PKN2	ENSG00000065243	NaN	[NaN]	[355]	1	hSpCas9	negative selection	10381327
88684607	88684630	1	+	28162770	TF1	viability	GATTCTGCTCACGGAACTGCAGG	PKN2	ENSG00000065243	NaN	[NaN]	[269]	1	hSpCas9	negative selection	10381328
88805937	88805960	1	-	28162770	TF1	viability	GAAGCTCGTGGTGGGGCTGGAGG	PKN2	ENSG00000065243	NaN	[NaN]	[134]	1	hSpCas9	negative selection	10381329
88771434	88771457	1	+	28162770	TF1	viability	AAGTCCTCTTGAACTTCGGATGG	PKN2	ENSG00000065243	NaN	[NaN]	[3]	1	hSpCas9	negative selection	10381330
88804511	88804534	1	-	28162770	TF1	viability	TCTGCAAATAAAGTACCCTGTGG	PKN2	ENSG00000065243	NaN	[NaN]	[121]	1	hSpCas9	negative selection	10381331
88805628	88805651	1	-	28162770	TF1	viability	GGGATGCGTACATCAACCACTGG	PKN2	ENSG00000065243	NaN	[NaN]	[251]	1	hSpCas9	negative selection	10381332
88805661	88805684	1	-	28162770	TF1	viability	TCAGACACATACCTAGCTGGAGG	PKN2	ENSG00000065243	NaN	[NaN]	[730]	1	hSpCas9	negative selection	10381333
88813660	88813683	1	+	28162770	TF1	viability	GTAATGGAATATGCTGCCGGTGG	PKN2	ENSG00000065243	NaN	[NaN]	[5]	1	hSpCas9	negative selection	10381334
88833109	88833132	1	+	28162770	TF1	viability	GGCTAGCGAGAAAGATGCAGAGG	PKN2	ENSG00000065243	NaN	[NaN]	[192]	1	hSpCas9	negative selection	10381335
88684581	88684604	1	+	28162770	TF1	viability	ATGGCGTCCAACCCCGAACGGGG	PKN2	ENSG00000065243	NaN	[NaN]	[119]	1	hSpCas9	negative selection	10381336
88770363	88770386	1	-	28162770	SKM1	viability	GCAGTTGCTGAGCTGTACCATGG	PKN2	ENSG00000065243	0.5052271806886659	[162]	[408]	5	hSpCas9	negative selection	10550693
88684607	88684630	1	+	28162770	SKM1	viability	GATTCTGCTCACGGAACTGCAGG	PKN2	ENSG00000065243	0.26992079141903375	[75]	[161]	2	hSpCas9	negative selection	10550694
88805937	88805960	1	-	28162770	SKM1	viability	GAAGCTCGTGGTGGGGCTGGAGG	PKN2	ENSG00000065243	-0.5171471164935844	[16]	[20]	-4	hSpCas9	negative selection	10550695
88771434	88771457	1	+	28162770	SKM1	viability	AAGTCCTCTTGAACTTCGGATGG	PKN2	ENSG00000065243	0.43175489422377766	[12]	[30]	4	hSpCas9	negative selection	10550696
88804511	88804534	1	-	28162770	SKM1	viability	TCTGCAAATAAAGTACCCTGTGG	PKN2	ENSG00000065243	-0.6699986045769556	[35]	[39]	-5	hSpCas9	negative selection	10550697
88805628	88805651	1	-	28162770	SKM1	viability	GGGATGCGTACATCAACCACTGG	PKN2	ENSG00000065243	0.10946692030717886	[96]	[184]	1	hSpCas9	negative selection	10550698
88805661	88805684	1	-	28162770	SKM1	viability	TCAGACACATACCTAGCTGGAGG	PKN2	ENSG00000065243	0.36020163319874365	[77]	[176]	3	hSpCas9	negative selection	10550699
88813660	88813683	1	+	28162770	SKM1	viability	GTAATGGAATATGCTGCCGGTGG	PKN2	ENSG00000065243	-0.3365748708517642	[9]	[13]	-3	hSpCas9	negative selection	10550700
88833109	88833132	1	+	28162770	SKM1	viability	GGCTAGCGAGAAAGATGCAGAGG	PKN2	ENSG00000065243	0.6754979614488115	[67]	[191]	6	hSpCas9	negative selection	10550701
88684581	88684604	1	+	28162770	SKM1	viability	ATGGCGTCCAACCCCGAACGGGG	PKN2	ENSG00000065243	0.2654611432283339	[31]	[67]	2	hSpCas9	negative selection	10550702
88770363	88770386	1	-	28162770	SKM1	viability	GCAGTTGCTGAGCTGTACCATGG	PKN2	ENSG00000065243	0.5052271806886659	[162]	[408]	5	hSpCas9	negative selection	10720059
88684607	88684630	1	+	28162770	SKM1	viability	GATTCTGCTCACGGAACTGCAGG	PKN2	ENSG00000065243	0.26992079141903375	[75]	[161]	2	hSpCas9	negative selection	10720060
88805937	88805960	1	-	28162770	SKM1	viability	GAAGCTCGTGGTGGGGCTGGAGG	PKN2	ENSG00000065243	-0.5171471164935844	[16]	[20]	-4	hSpCas9	negative selection	10720061
88771434	88771457	1	+	28162770	SKM1	viability	AAGTCCTCTTGAACTTCGGATGG	PKN2	ENSG00000065243	0.43175489422377766	[12]	[30]	4	hSpCas9	negative selection	10720062
88804511	88804534	1	-	28162770	SKM1	viability	TCTGCAAATAAAGTACCCTGTGG	PKN2	ENSG00000065243	-0.6699986045769556	[35]	[39]	-5	hSpCas9	negative selection	10720063
88805628	88805651	1	-	28162770	SKM1	viability	GGGATGCGTACATCAACCACTGG	PKN2	ENSG00000065243	0.10946692030717886	[96]	[184]	1	hSpCas9	negative selection	10720064
88805661	88805684	1	-	28162770	SKM1	viability	TCAGACACATACCTAGCTGGAGG	PKN2	ENSG00000065243	0.36020163319874365	[77]	[176]	3	hSpCas9	negative selection	10720065
88813660	88813683	1	+	28162770	SKM1	viability	GTAATGGAATATGCTGCCGGTGG	PKN2	ENSG00000065243	-0.3365748708517642	[9]	[13]	-3	hSpCas9	negative selection	10720066
88833109	88833132	1	+	28162770	SKM1	viability	GGCTAGCGAGAAAGATGCAGAGG	PKN2	ENSG00000065243	0.6754979614488115	[67]	[191]	6	hSpCas9	negative selection	10720067
88684581	88684604	1	+	28162770	SKM1	viability	ATGGCGTCCAACCCCGAACGGGG	PKN2	ENSG00000065243	0.2654611432283339	[31]	[67]	2	hSpCas9	negative selection	10720068
88770363	88770386	1	-	28162770	PL21	viability	GCAGTTGCTGAGCTGTACCATGG	PKN2	ENSG00000065243	0.42008055683167145	[588]	[342]	3	hSpCas9	negative selection	10889425
88684607	88684630	1	+	28162770	PL21	viability	GATTCTGCTCACGGAACTGCAGG	PKN2	ENSG00000065243	-1.1560041957359553	[255]	[49]	-6	hSpCas9	negative selection	10889426
88805937	88805960	1	-	28162770	PL21	viability	GAAGCTCGTGGTGGGGCTGGAGG	PKN2	ENSG00000065243	1.911794120126339	[68]	[112]	9	hSpCas9	negative selection	10889427
88771434	88771457	1	+	28162770	PL21	viability	AAGTCCTCTTGAACTTCGGATGG	PKN2	ENSG00000065243	1.299675288040235	[13]	[14]	9	hSpCas9	negative selection	10889428
88804511	88804534	1	-	28162770	PL21	viability	TCTGCAAATAAAGTACCCTGTGG	PKN2	ENSG00000065243	0.8713031502597803	[156]	[124]	7	hSpCas9	negative selection	10889429
88805628	88805651	1	-	28162770	PL21	viability	GGGATGCGTACATCAACCACTGG	PKN2	ENSG00000065243	0.338714844397902	[366]	[201]	3	hSpCas9	negative selection	10889430
88805661	88805684	1	-	28162770	PL21	viability	TCAGACACATACCTAGCTGGAGG	PKN2	ENSG00000065243	-0.35360415562111575	[319]	[108]	-3	hSpCas9	negative selection	10889431
88813660	88813683	1	+	28162770	PL21	viability	GTAATGGAATATGCTGCCGGTGG	PKN2	ENSG00000065243	-1.8873232267610196	[33]	[3]	-8	hSpCas9	negative selection	10889432
88833109	88833132	1	+	28162770	PL21	viability	GGCTAGCGAGAAAGATGCAGAGG	PKN2	ENSG00000065243	0.7680286018515348	[169]	[125]	6	hSpCas9	negative selection	10889433
88684581	88684604	1	+	28162770	PL21	viability	ATGGCGTCCAACCCCGAACGGGG	PKN2	ENSG00000065243	0.6512463684756858	[78]	[53]	5	hSpCas9	negative selection	10889434
88770363	88770386	1	-	28162770	P31FUJ	viability	GCAGTTGCTGAGCTGTACCATGG	PKN2	ENSG00000065243	0.7491551982037397	[522]	[1032]	8	hSpCas9	negative selection	11058791
88684607	88684630	1	+	28162770	P31FUJ	viability	GATTCTGCTCACGGAACTGCAGG	PKN2	ENSG00000065243	0.06560653152130032	[234]	[288]	0	hSpCas9	negative selection	11058792
88805937	88805960	1	-	28162770	P31FUJ	viability	GAAGCTCGTGGTGGGGCTGGAGG	PKN2	ENSG00000065243	-0.12115684858546927	[86]	[93]	-1	hSpCas9	negative selection	11058793
88771434	88771457	1	+	28162770	P31FUJ	viability	AAGTCCTCTTGAACTTCGGATGG	PKN2	ENSG00000065243	0.9934736514092977	[52]	[123]	9	hSpCas9	negative selection	11058794
88804511	88804534	1	-	28162770	P31FUJ	viability	TCTGCAAATAAAGTACCCTGTGG	PKN2	ENSG00000065243	0.8388992609398103	[156]	[329]	8	hSpCas9	negative selection	11058795
88805628	88805651	1	-	28162770	P31FUJ	viability	GGGATGCGTACATCAACCACTGG	PKN2	ENSG00000065243	0.25443667454219754	[340]	[477]	2	hSpCas9	negative selection	11058796
88805661	88805684	1	-	28162770	P31FUJ	viability	TCAGACACATACCTAGCTGGAGG	PKN2	ENSG00000065243	0.2453535697797592	[340]	[474]	2	hSpCas9	negative selection	11058797
88813660	88813683	1	+	28162770	P31FUJ	viability	GTAATGGAATATGCTGCCGGTGG	PKN2	ENSG00000065243	-0.5409244997767102	[25]	[20]	-4	hSpCas9	negative selection	11058798
88833109	88833132	1	+	28162770	P31FUJ	viability	GGCTAGCGAGAAAGATGCAGAGG	PKN2	ENSG00000065243	0.5498409641464718	[285]	[491]	6	hSpCas9	negative selection	11058799
88684581	88684604	1	+	28162770	P31FUJ	viability	ATGGCGTCCAACCCCGAACGGGG	PKN2	ENSG00000065243	0.11600159646437846	[116]	[148]	1	hSpCas9	negative selection	11058800
88770363	88770386	1	-	28162770	OCIAML5	viability	GCAGTTGCTGAGCTGTACCATGG	PKN2	ENSG00000065243	0.3215247477760852	[261]	[590]	2	hSpCas9	negative selection	11228157
88684607	88684630	1	+	28162770	OCIAML5	viability	GATTCTGCTCACGGAACTGCAGG	PKN2	ENSG00000065243	0.5890087893163702	[150]	[409]	5	hSpCas9	negative selection	11228158
88805937	88805960	1	-	28162770	OCIAML5	viability	GAAGCTCGTGGTGGGGCTGGAGG	PKN2	ENSG00000065243	-0.6041390574204117	[47]	[56]	-4	hSpCas9	negative selection	11228159
88771434	88771457	1	+	28162770	OCIAML5	viability	AAGTCCTCTTGAACTTCGGATGG	PKN2	ENSG00000065243	-0.6176013172269743	[33]	[39]	-4	hSpCas9	negative selection	11228160
88804511	88804534	1	-	28162770	OCIAML5	viability	TCTGCAAATAAAGTACCCTGTGG	PKN2	ENSG00000065243	0.7080212612181299	[77]	[229]	6	hSpCas9	negative selection	11228161
88805628	88805651	1	-	28162770	OCIAML5	viability	GGGATGCGTACATCAACCACTGG	PKN2	ENSG00000065243	0.3296218798941535	[189]	[430]	3	hSpCas9	negative selection	11228162
88805661	88805684	1	-	28162770	OCIAML5	viability	TCAGACACATACCTAGCTGGAGG	PKN2	ENSG00000065243	0.2572584195743437	[234]	[506]	2	hSpCas9	negative selection	11228163
88813660	88813683	1	+	28162770	OCIAML5	viability	GTAATGGAATATGCTGCCGGTGG	PKN2	ENSG00000065243	-3.6594214929216013	[13]	[1]	-9	hSpCas9	negative selection	11228164
88833109	88833132	1	+	28162770	OCIAML5	viability	GGCTAGCGAGAAAGATGCAGAGG	PKN2	ENSG00000065243	1.1139860972126654	[128]	[503]	8	hSpCas9	negative selection	11228165
88684581	88684604	1	+	28162770	OCIAML5	viability	ATGGCGTCCAACCCCGAACGGGG	PKN2	ENSG00000065243	0.7870516999040646	[60]	[189]	7	hSpCas9	negative selection	11228166
88770363	88770386	1	-	28162770	EOL1	viability	GCAGTTGCTGAGCTGTACCATGG	PKN2	ENSG00000065243	0.2981364930306316	[970]	[628]	2	hSpCas9	negative selection	11397523
88684607	88684630	1	+	28162770	EOL1	viability	GATTCTGCTCACGGAACTGCAGG	PKN2	ENSG00000065243	0.005467766954101935	[311]	[164]	0	hSpCas9	negative selection	11397524
88805937	88805960	1	-	28162770	EOL1	viability	GAAGCTCGTGGTGGGGCTGGAGG	PKN2	ENSG00000065243	1.5253468203423997	[150]	[228]	9	hSpCas9	negative selection	11397525
88771434	88771457	1	+	28162770	EOL1	viability	AAGTCCTCTTGAACTTCGGATGG	PKN2	ENSG00000065243	-2.2718494412329693	[54]	[5]	-8	hSpCas9	negative selection	11397526
88804511	88804534	1	-	28162770	EOL1	viability	TCTGCAAATAAAGTACCCTGTGG	PKN2	ENSG00000065243	-0.6083262180021676	[271]	[93]	-4	hSpCas9	negative selection	11397527
88805628	88805651	1	-	28162770	EOL1	viability	GGGATGCGTACATCAACCACTGG	PKN2	ENSG00000065243	-0.22984983701489825	[669]	[300]	-2	hSpCas9	negative selection	11397528
88805661	88805684	1	-	28162770	EOL1	viability	TCAGACACATACCTAGCTGGAGG	PKN2	ENSG00000065243	-0.3096862624104298	[366]	[155]	-2	hSpCas9	negative selection	11397529
88813660	88813683	1	+	28162770	EOL1	viability	GTAATGGAATATGCTGCCGGTGG	PKN2	ENSG00000065243	0.6350411543755499	[21]	[17]	5	hSpCas9	negative selection	11397530
88833109	88833132	1	+	28162770	EOL1	viability	GGCTAGCGAGAAAGATGCAGAGG	PKN2	ENSG00000065243	-1.3649588456244504	[219]	[44]	-7	hSpCas9	negative selection	11397531
88684581	88684604	1	+	28162770	EOL1	viability	ATGGCGTCCAACCCCGAACGGGG	PKN2	ENSG00000065243	0.8129024157416255	[93]	[86]	7	hSpCas9	negative selection	11397532
88770363	88770386	1	-	28162770	MOLM13	viability	GCAGTTGCTGAGCTGTACCATGG	PKN2	ENSG00000065243	0.923605834277218	[812]	[1114]	7	hSpCas9	negative selection	11566889
88684607	88684630	1	+	28162770	MOLM13	viability	GATTCTGCTCACGGAACTGCAGG	PKN2	ENSG00000065243	1.305373969786571	[351]	[628]	8	hSpCas9	negative selection	11566890
88805937	88805960	1	-	28162770	MOLM13	viability	GAAGCTCGTGGTGGGGCTGGAGG	PKN2	ENSG00000065243	-1.37713595847908	[96]	[26]	-6	hSpCas9	negative selection	11566891
88771434	88771457	1	+	28162770	MOLM13	viability	AAGTCCTCTTGAACTTCGGATGG	PKN2	ENSG00000065243	-0.4311817096046404	[68]	[36]	-3	hSpCas9	negative selection	11566892
88804511	88804534	1	-	28162770	MOLM13	viability	TCTGCAAATAAAGTACCCTGTGG	PKN2	ENSG00000065243	0.26198508299669987	[202]	[175]	2	hSpCas9	negative selection	11566893
88805628	88805651	1	-	28162770	MOLM13	viability	GGGATGCGTACATCAACCACTGG	PKN2	ENSG00000065243	0.9736088272566368	[473]	[672]	7	hSpCas9	negative selection	11566894
88805661	88805684	1	-	28162770	MOLM13	viability	TCAGACACATACCTAGCTGGAGG	PKN2	ENSG00000065243	-0.37580738757674553	[401]	[223]	-2	hSpCas9	negative selection	11566895
88813660	88813683	1	+	28162770	MOLM13	viability	GTAATGGAATATGCTGCCGGTGG	PKN2	ENSG00000065243	1.574804585461091	[25]	[55]	9	hSpCas9	negative selection	11566896
88833109	88833132	1	+	28162770	MOLM13	viability	GGCTAGCGAGAAAGATGCAGAGG	PKN2	ENSG00000065243	1.5872781107349094	[254]	[553]	9	hSpCas9	negative selection	11566897
88684581	88684604	1	+	28162770	MOLM13	viability	ATGGCGTCCAACCCCGAACGGGG	PKN2	ENSG00000065243	0.2173459198939819	[137]	[115]	1	hSpCas9	negative selection	11566898
88770363	88770386	1	-	28162770	HEL	viability	GCAGTTGCTGAGCTGTACCATGG	PKN2	ENSG00000065243	0.6097740686525706	[663]	[648]	5	hSpCas9	negative selection	11736255
88684607	88684630	1	+	28162770	HEL	viability	GATTCTGCTCACGGAACTGCAGG	PKN2	ENSG00000065243	0.7013930497211673	[240]	[250]	6	hSpCas9	negative selection	11736256
88805937	88805960	1	-	28162770	HEL	viability	GAAGCTCGTGGTGGGGCTGGAGG	PKN2	ENSG00000065243	0.057776331279200566	[83]	[55]	0	hSpCas9	negative selection	11736257
88771434	88771457	1	+	28162770	HEL	viability	AAGTCCTCTTGAACTTCGGATGG	PKN2	ENSG00000065243	-0.2359548717775093	[56]	[30]	-2	hSpCas9	negative selection	11736258
88804511	88804534	1	-	28162770	HEL	viability	TCTGCAAATAAAGTACCCTGTGG	PKN2	ENSG00000065243	0.8566364591713493	[218]	[253]	7	hSpCas9	negative selection	11736259
88805628	88805651	1	-	28162770	HEL	viability	GGGATGCGTACATCAACCACTGG	PKN2	ENSG00000065243	0.6239208037981901	[462]	[456]	5	hSpCas9	negative selection	11736260
88805661	88805684	1	-	28162770	HEL	viability	TCAGACACATACCTAGCTGGAGG	PKN2	ENSG00000065243	-0.6660138741392723	[326]	[131]	-4	hSpCas9	negative selection	11736261
88813660	88813683	1	+	28162770	HEL	viability	GTAATGGAATATGCTGCCGGTGG	PKN2	ENSG00000065243	-0.9422236687207994	[26]	[8]	-5	hSpCas9	negative selection	11736262
88833109	88833132	1	+	28162770	HEL	viability	GGCTAGCGAGAAAGATGCAGAGG	PKN2	ENSG00000065243	-1.6617722098095962	[246]	[49]	-7	hSpCas9	negative selection	11736263
88684581	88684604	1	+	28162770	HEL	viability	ATGGCGTCCAACCCCGAACGGGG	PKN2	ENSG00000065243	1.2393831377691487	[81]	[123]	9	hSpCas9	negative selection	11736264
88770363	88770386	1	-	28162770	MV411	viability	GCAGTTGCTGAGCTGTACCATGG	PKN2	ENSG00000065243	0.5433612494305555	[570]	[700]	5	hSpCas9	negative selection	11905621
88684607	88684630	1	+	28162770	MV411	viability	GATTCTGCTCACGGAACTGCAGG	PKN2	ENSG00000065243	0.42386411816704295	[245]	[277]	4	hSpCas9	negative selection	11905622
88805937	88805960	1	-	28162770	MV411	viability	GAAGCTCGTGGTGGGGCTGGAGG	PKN2	ENSG00000065243	1.5522921323111964	[67]	[167]	9	hSpCas9	negative selection	11905623
88771434	88771457	1	+	28162770	MV411	viability	AAGTCCTCTTGAACTTCGGATGG	PKN2	ENSG00000065243	2.0820139415754038	[29]	[106]	9	hSpCas9	negative selection	11905624
88804511	88804534	1	-	28162770	MV411	viability	TCTGCAAATAAAGTACCCTGTGG	PKN2	ENSG00000065243	1.1819844892941593	[123]	[236]	9	hSpCas9	negative selection	11905625
88805628	88805651	1	-	28162770	MV411	viability	GGGATGCGTACATCAACCACTGG	PKN2	ENSG00000065243	0.2390740778481487	[345]	[343]	2	hSpCas9	negative selection	11905626
88805661	88805684	1	-	28162770	MV411	viability	TCAGACACATACCTAGCTGGAGG	PKN2	ENSG00000065243	0.9804986904930655	[221]	[368]	8	hSpCas9	negative selection	11905627
88813660	88813683	1	+	28162770	MV411	viability	GTAATGGAATATGCTGCCGGTGG	PKN2	ENSG00000065243	-0.8900659729671596	[32]	[14]	-6	hSpCas9	negative selection	11905628
88833109	88833132	1	+	28162770	MV411	viability	GGCTAGCGAGAAAGATGCAGAGG	PKN2	ENSG00000065243	-0.4363031044165545	[203]	[126]	-3	hSpCas9	negative selection	11905629
88684581	88684604	1	+	28162770	MV411	viability	ATGGCGTCCAACCCCGAACGGGG	PKN2	ENSG00000065243	1.1012168099317314	[82]	[149]	8	hSpCas9	negative selection	11905630
88770363	88770386	1	-	28162770	MONOMAC1	viability	GCAGTTGCTGAGCTGTACCATGG	PKN2	ENSG00000065243	-0.06935429412064598	[334]	[365]	0	hSpCas9	negative selection	12074987
88684607	88684630	1	+	28162770	MONOMAC1	viability	GATTCTGCTCACGGAACTGCAGG	PKN2	ENSG00000065243	-0.07602144609818767	[159]	[173]	0	hSpCas9	negative selection	12074988
88805937	88805960	1	-	28162770	MONOMAC1	viability	GAAGCTCGTGGTGGGGCTGGAGG	PKN2	ENSG00000065243	0.015507788320547	[62]	[72]	0	hSpCas9	negative selection	12074989
88771434	88771457	1	+	28162770	MONOMAC1	viability	AAGTCCTCTTGAACTTCGGATGG	PKN2	ENSG00000065243	0.10781773446886689	[16]	[20]	1	hSpCas9	negative selection	12074990
88804511	88804534	1	-	28162770	MONOMAC1	viability	TCTGCAAATAAAGTACCCTGTGG	PKN2	ENSG00000065243	-0.07839235056093469	[104]	[113]	0	hSpCas9	negative selection	12074991
88805628	88805651	1	-	28162770	MONOMAC1	viability	GGGATGCGTACATCAACCACTGG	PKN2	ENSG00000065243	0.6176976053636479	[194]	[342]	6	hSpCas9	negative selection	12074992
88805661	88805684	1	-	28162770	MONOMAC1	viability	TCAGACACATACCTAGCTGGAGG	PKN2	ENSG00000065243	0.39400016807128674	[157]	[237]	4	hSpCas9	negative selection	12074993
88813660	88813683	1	+	28162770	MONOMAC1	viability	GTAATGGAATATGCTGCCGGTGG	PKN2	ENSG00000065243	-0.8137082075080477	[22]	[14]	-6	hSpCas9	negative selection	12074994
88833109	88833132	1	+	28162770	MONOMAC1	viability	GGCTAGCGAGAAAGATGCAGAGG	PKN2	ENSG00000065243	0.16406184510848634	[108]	[139]	1	hSpCas9	negative selection	12074995
88684581	88684604	1	+	28162770	MONOMAC1	viability	ATGGCGTCCAACCCCGAACGGGG	PKN2	ENSG00000065243	-0.7819993477807101	[47]	[31]	-6	hSpCas9	negative selection	12074996
88770363	88770386	1	-	28162770	OCIAML2	viability	GCAGTTGCTGAGCTGTACCATGG	PKN2	ENSG00000065243	0.7152367200691729	[99]	[909]	7	hSpCas9	negative selection	12244353
88684607	88684630	1	+	28162770	OCIAML2	viability	GATTCTGCTCACGGAACTGCAGG	PKN2	ENSG00000065243	0.20360001357608248	[46]	[299]	2	hSpCas9	negative selection	12244354
88805937	88805960	1	-	28162770	OCIAML2	viability	GAAGCTCGTGGTGGGGCTGGAGG	PKN2	ENSG00000065243	0.3495491371730267	[15]	[112]	3	hSpCas9	negative selection	12244355
88771434	88771457	1	+	28162770	OCIAML2	viability	AAGTCCTCTTGAACTTCGGATGG	PKN2	ENSG00000065243	-0.37109415169124693	[6]	[29]	-3	hSpCas9	negative selection	12244356
88804511	88804534	1	-	28162770	OCIAML2	viability	TCTGCAAATAAAGTACCCTGTGG	PKN2	ENSG00000065243	0.4455385839543681	[30]	[233]	4	hSpCas9	negative selection	12244357
88805628	88805651	1	-	28162770	OCIAML2	viability	GGGATGCGTACATCAACCACTGG	PKN2	ENSG00000065243	1.009727632249684	[55]	[624]	8	hSpCas9	negative selection	12244358
88805661	88805684	1	-	28162770	OCIAML2	viability	TCAGACACATACCTAGCTGGAGG	PKN2	ENSG00000065243	0.8679770107918314	[42]	[434]	8	hSpCas9	negative selection	12244359
88813660	88813683	1	+	28162770	OCIAML2	viability	GTAATGGAATATGCTGCCGGTGG	PKN2	ENSG00000065243	-1.2779847472997656	[6]	[15]	-7	hSpCas9	negative selection	12244360
88833109	88833132	1	+	28162770	OCIAML2	viability	GGCTAGCGAGAAAGATGCAGAGG	PKN2	ENSG00000065243	0.5859537031242061	[24]	[207]	6	hSpCas9	negative selection	12244361
88684581	88684604	1	+	28162770	OCIAML2	viability	ATGGCGTCCAACCCCGAACGGGG	PKN2	ENSG00000065243	1.0389252728209726	[17]	[204]	8	hSpCas9	negative selection	12244362
88770363	88770386	1	-	28162770	OCIAML3	viability	GCAGTTGCTGAGCTGTACCATGG	PKN2	ENSG00000065243	0.06250812142202689	[176]	[557]	0	hSpCas9	negative selection	12413719
88684607	88684630	1	+	28162770	OCIAML3	viability	GATTCTGCTCACGGAACTGCAGG	PKN2	ENSG00000065243	-0.161048233048057	[49]	[134]	-1	hSpCas9	negative selection	12413720
88805937	88805960	1	-	28162770	OCIAML3	viability	GAAGCTCGTGGTGGGGCTGGAGG	PKN2	ENSG00000065243	0.91295234839572	[18]	[107]	7	hSpCas9	negative selection	12413721
88771434	88771457	1	+	28162770	OCIAML3	viability	AAGTCCTCTTGAACTTCGGATGG	PKN2	ENSG00000065243	0.3653503751784912	[8]	[34]	3	hSpCas9	negative selection	12413722
88804511	88804534	1	-	28162770	OCIAML3	viability	TCTGCAAATAAAGTACCCTGTGG	PKN2	ENSG00000065243	0.4154526889249033	[37]	[152]	4	hSpCas9	negative selection	12413723
88805628	88805651	1	-	28162770	OCIAML3	viability	GGGATGCGTACATCAACCACTGG	PKN2	ENSG00000065243	0.31492788126937965	[93]	[352]	3	hSpCas9	negative selection	12413724
88805661	88805684	1	-	28162770	OCIAML3	viability	TCAGACACATACCTAGCTGGAGG	PKN2	ENSG00000065243	-0.26538489286279254	[85]	[215]	-2	hSpCas9	negative selection	12413725
88813660	88813683	1	+	28162770	OCIAML3	viability	GTAATGGAATATGCTGCCGGTGG	PKN2	ENSG00000065243	-3.1789701410453195	[5]	[1]	-9	hSpCas9	negative selection	12413726
88833109	88833132	1	+	28162770	OCIAML3	viability	GGCTAGCGAGAAAGATGCAGAGG	PKN2	ENSG00000065243	-0.6720101523254363	[56]	[107]	-5	hSpCas9	negative selection	12413727
88684581	88684604	1	+	28162770	OCIAML3	viability	ATGGCGTCCAACCCCGAACGGGG	PKN2	ENSG00000065243	0.16680469579641066	[17]	[60]	1	hSpCas9	negative selection	12413728