Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:8502
• Symbol:PKP4
• Description:plakophilin 4

DataSource: http://genomecrispr.dkfz.de/#!/results/PKP4

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
158533235	158533258	2	-	26472758	Jiyoye	viability	CAGTGGAGGCAGCTTCCTGGCGG	PKP4	ENSG00000144283	0.7831038437456006	[214]	[278]	5	hSpCas9	negative selection	121435
158533188	158533211	2	-	26472758	Jiyoye	viability	AATGAGGCCTGCTCAGGAGCTGG	PKP4	ENSG00000144283	-1.3400585481141598	[187]	[55]	-7	hSpCas9	negative selection	121436
158625197	158625220	2	-	26472758	Jiyoye	viability	TGGGGACCCCACTCTGGCGGTGG	PKP4	ENSG00000144283	0.9033286152691735	[133]	[188]	6	hSpCas9	negative selection	121437
158625210	158625233	2	+	26472758	Jiyoye	viability	GGGGTCCCCACTGACCCTGACGG	PKP4	ENSG00000144283	-0.24590214413989464	[205]	[130]	-2	hSpCas9	negative selection	121438
158631799	158631822	2	-	26472758	Jiyoye	viability	CGGGAGACACGGCAGAACGAAGG	PKP4	ENSG00000144283	1.272245801419765	[83]	[152]	7	hSpCas9	negative selection	121439
158631869	158631892	2	+	26472758	Jiyoye	viability	GTGTACCGCAGCCCAAACCATGG	PKP4	ENSG00000144283	1.2844323167936336	[140]	[258]	7	hSpCas9	negative selection	121440
158533235	158533258	2	-	26472758	KBM7	viability	CAGTGGAGGCAGCTTCCTGGCGG	PKP4	ENSG00000144283	0.6661844244659041	[1293,870]	[965,642]	7	hSpCas9	negative selection	312553
158533188	158533211	2	-	26472758	KBM7	viability	AATGAGGCCTGCTCAGGAGCTGG	PKP4	ENSG00000144283	0.9283746583911743	[642,413]	[582,358]	8	hSpCas9	negative selection	312554
158625197	158625220	2	-	26472758	KBM7	viability	TGGGGACCCCACTCTGGCGGTGG	PKP4	ENSG00000144283	0.0169740912797696	[545,366]	[234,194]	0	hSpCas9	negative selection	312555
158625210	158625233	2	+	26472758	KBM7	viability	GGGGTCCCCACTGACCCTGACGG	PKP4	ENSG00000144283	0.6527029684437952	[602,444]	[321,437]	7	hSpCas9	negative selection	312556
158631799	158631822	2	-	26472758	KBM7	viability	CGGGAGACACGGCAGAACGAAGG	PKP4	ENSG00000144283	0.42717212650784936	[542,428]	[284,322]	4	hSpCas9	negative selection	312557
158631869	158631892	2	+	26472758	KBM7	viability	GTGTACCGCAGCCCAAACCATGG	PKP4	ENSG00000144283	0.426496474115993	[861,846]	[539,543]	4	hSpCas9	negative selection	312558
158533235	158533258	2	-	26472758	Raji	viability	CAGTGGAGGCAGCTTCCTGGCGG	PKP4	ENSG00000144283	0.7309574853647305	[552]	[212]	6	hSpCas9	negative selection	503671
158533188	158533211	2	-	26472758	Raji	viability	AATGAGGCCTGCTCAGGAGCTGG	PKP4	ENSG00000144283	-0.5428704255992759	[338]	[53]	-4	hSpCas9	negative selection	503672
158625197	158625220	2	-	26472758	Raji	viability	TGGGGACCCCACTCTGGCGGTGG	PKP4	ENSG00000144283	0.3531399497755578	[279]	[82]	3	hSpCas9	negative selection	503673
158625210	158625233	2	+	26472758	Raji	viability	GGGGTCCCCACTGACCCTGACGG	PKP4	ENSG00000144283	-0.16984475204294852	[285]	[58]	-1	hSpCas9	negative selection	503674
158631799	158631822	2	-	26472758	Raji	viability	CGGGAGACACGGCAGAACGAAGG	PKP4	ENSG00000144283	1.255229003344993	[138]	[76]	9	hSpCas9	negative selection	503675
158631869	158631892	2	+	26472758	Raji	viability	GTGTACCGCAGCCCAAACCATGG	PKP4	ENSG00000144283	-0.2782701571241498	[485]	[92]	-2	hSpCas9	negative selection	503676
158533235	158533258	2	-	26472758	K562	viability	CAGTGGAGGCAGCTTCCTGGCGG	PKP4	ENSG00000144283	-0.06160130587698087	[946]	[765]	0	hSpCas9	negative selection	694789
158533188	158533211	2	-	26472758	K562	viability	AATGAGGCCTGCTCAGGAGCTGG	PKP4	ENSG00000144283	0.19426205269428767	[438]	[423]	1	hSpCas9	negative selection	694790
158625197	158625220	2	-	26472758	K562	viability	TGGGGACCCCACTCTGGCGGTGG	PKP4	ENSG00000144283	0.09146680482784797	[506]	[455]	0	hSpCas9	negative selection	694791
158625210	158625233	2	+	26472758	K562	viability	GGGGTCCCCACTGACCCTGACGG	PKP4	ENSG00000144283	0.11666318046807417	[353]	[323]	0	hSpCas9	negative selection	694792
158631799	158631822	2	-	26472758	K562	viability	CGGGAGACACGGCAGAACGAAGG	PKP4	ENSG00000144283	0.7510528677026435	[327]	[465]	6	hSpCas9	negative selection	694793
158631869	158631892	2	+	26472758	K562	viability	GTGTACCGCAGCCCAAACCATGG	PKP4	ENSG00000144283	-0.45091237779179566	[739]	[456]	-3	hSpCas9	negative selection	694794
158533199	158533222	2	+	26627737	DLD1	viability	GCAGGCCTCATTGGTGGAGGAGG	PKP4	ENSG00000144283	0.7390987035450933	[315]	[190,140,161]	7	hSpCas9	negative selection	808952
158577362	158577385	2	+	26627737	DLD1	viability	CACCAAGCATCGCCAGCACCAGG	PKP4	ENSG00000144283	0.7718285735229824	[933]	[443,595,464]	7	hSpCas9	negative selection	808953
158624956	158624979	2	+	26627737	DLD1	viability	ACAGGCGTGTCTCCTTCAAGGGG	PKP4	ENSG00000144283	0.7767722701552326	[315]	[227,136,144]	7	hSpCas9	negative selection	808954
158631923	158631946	2	+	26627737	DLD1	viability	TTGTATCGCACAGGTTCAGGTGG	PKP4	ENSG00000144283	0.8658024411480992	[283]	[86,147,237]	8	hSpCas9	negative selection	808955
158533199	158533222	2	+	26627737	GBM cells	viability after 5 days	GCAGGCCTCATTGGTGGAGGAGG	PKP4	ENSG00000144283	0.25736784579816185	[77]	[44,54]	4	hSpCas9	negative selection	891267
158577362	158577385	2	+	26627737	GBM cells	viability after 5 days	CACCAAGCATCGCCAGCACCAGG	PKP4	ENSG00000144283	0.36596217274107257	[394]	[271,273]	5	hSpCas9	negative selection	891268
158624956	158624979	2	+	26627737	GBM cells	viability after 5 days	ACAGGCGTGTCTCCTTCAAGGGG	PKP4	ENSG00000144283	0.47628322628461134	[253]	[188,189]	7	hSpCas9	negative selection	891269
158631923	158631946	2	+	26627737	GBM cells	viability after 5 days	TTGTATCGCACAGGTTCAGGTGG	PKP4	ENSG00000144283	0.11999296427810113	[156]	[111,70]	2	hSpCas9	negative selection	891270
158533199	158533222	2	+	26627737	GBM cells	viability after 13 days	GCAGGCCTCATTGGTGGAGGAGG	PKP4	ENSG00000144283	0.8571362080618723	[77]	[90,64]	8	hSpCas9	negative selection	973582
158577362	158577385	2	+	26627737	GBM cells	viability after 13 days	CACCAAGCATCGCCAGCACCAGG	PKP4	ENSG00000144283	-0.11253568466713637	[394]	[259,147]	-1	hSpCas9	negative selection	973583
158624956	158624979	2	+	26627737	GBM cells	viability after 13 days	ACAGGCGTGTCTCCTTCAAGGGG	PKP4	ENSG00000144283	0.7996016555725387	[253]	[283,203]	8	hSpCas9	negative selection	973584
158631923	158631946	2	+	26627737	GBM cells	viability after 13 days	TTGTATCGCACAGGTTCAGGTGG	PKP4	ENSG00000144283	-0.1842648085413171	[156]	[85,65]	-2	hSpCas9	negative selection	973585
158533199	158533222	2	+	26627737	GBM cells	viability after 21 days	GCAGGCCTCATTGGTGGAGGAGG	PKP4	ENSG00000144283	1.0714647894656457	[77]	[75,100]	9	hSpCas9	negative selection	1055897
158577362	158577385	2	+	26627737	GBM cells	viability after 21 days	CACCAAGCATCGCCAGCACCAGG	PKP4	ENSG00000144283	-0.47142100228986616	[394]	[159,149]	-4	hSpCas9	negative selection	1055898
158624956	158624979	2	+	26627737	GBM cells	viability after 21 days	ACAGGCGTGTCTCCTTCAAGGGG	PKP4	ENSG00000144283	0.4725817704859259	[253]	[191,190]	5	hSpCas9	negative selection	1055899
158631923	158631946	2	+	26627737	GBM cells	viability after 21 days	TTGTATCGCACAGGTTCAGGTGG	PKP4	ENSG00000144283	-0.7372551046269454	[156]	[58,43]	-6	hSpCas9	negative selection	1055900
158533199	158533222	2	+	26627737	RPE1	viability after 9 days	GCAGGCCTCATTGGTGGAGGAGG	PKP4	ENSG00000144283	-0.6210937702193121	[667]	[90,193]	-4	hSpCas9	negative selection	1138212
158577362	158577385	2	+	26627737	RPE1	viability after 9 days	CACCAAGCATCGCCAGCACCAGG	PKP4	ENSG00000144283	0.6471485963022253	[859]	[215,686]	4	hSpCas9	negative selection	1138213
158624956	158624979	2	+	26627737	RPE1	viability after 9 days	ACAGGCGTGTCTCCTTCAAGGGG	PKP4	ENSG00000144283	-0.40060178408569436	[1015]	[219,267]	-3	hSpCas9	negative selection	1138214
158631923	158631946	2	+	26627737	RPE1	viability after 9 days	TTGTATCGCACAGGTTCAGGTGG	PKP4	ENSG00000144283	-0.7464198733654138	[684]	[43,235]	-5	hSpCas9	negative selection	1138215
158533199	158533222	2	+	26627737	RPE1	viability after 12 days	GCAGGCCTCATTGGTGGAGGAGG	PKP4	ENSG00000144283	-0.4113880775953157	[667]	[183,82]	-3	hSpCas9	negative selection	1220527
158577362	158577385	2	+	26627737	RPE1	viability after 12 days	CACCAAGCATCGCCAGCACCAGG	PKP4	ENSG00000144283	1.0355308653738322	[859]	[426,522]	6	hSpCas9	negative selection	1220528
158624956	158624979	2	+	26627737	RPE1	viability after 12 days	ACAGGCGTGTCTCCTTCAAGGGG	PKP4	ENSG00000144283	-0.3563163212582968	[1015]	[237,186]	-2	hSpCas9	negative selection	1220529
158631923	158631946	2	+	26627737	RPE1	viability after 12 days	TTGTATCGCACAGGTTCAGGTGG	PKP4	ENSG00000144283	-0.22896549430161764	[684]	[123,191]	-1	hSpCas9	negative selection	1220530
158533199	158533222	2	+	26627737	RPE1	viability after 15 days	GCAGGCCTCATTGGTGGAGGAGG	PKP4	ENSG00000144283	-0.5738876856361464	[667]	[129,123]	-4	hSpCas9	negative selection	1302842
158577362	158577385	2	+	26627737	RPE1	viability after 15 days	CACCAAGCATCGCCAGCACCAGG	PKP4	ENSG00000144283	0.9574432888069176	[859]	[336,602]	6	hSpCas9	negative selection	1302843
158624956	158624979	2	+	26627737	RPE1	viability after 15 days	ACAGGCGTGTCTCCTTCAAGGGG	PKP4	ENSG00000144283	-1.2865350584763315	[1015]	[99,134]	-7	hSpCas9	negative selection	1302844
158631923	158631946	2	+	26627737	RPE1	viability after 15 days	TTGTATCGCACAGGTTCAGGTGG	PKP4	ENSG00000144283	0.2004180996174024	[684]	[157,284]	1	hSpCas9	negative selection	1302845
158533199	158533222	2	+	26627737	RPE1	viability after 18 days	GCAGGCCTCATTGGTGGAGGAGG	PKP4	ENSG00000144283	-0.3167227793962809	[667]	[107,183]	-2	hSpCas9	negative selection	1385157
158577362	158577385	2	+	26627737	RPE1	viability after 18 days	CACCAAGCATCGCCAGCACCAGG	PKP4	ENSG00000144283	0.9140909714032904	[859]	[388,488]	5	hSpCas9	negative selection	1385158
158624956	158624979	2	+	26627737	RPE1	viability after 18 days	ACAGGCGTGTCTCCTTCAAGGGG	PKP4	ENSG00000144283	-0.3008786649689172	[1015]	[282,157]	-2	hSpCas9	negative selection	1385159
158631923	158631946	2	+	26627737	RPE1	viability after 18 days	TTGTATCGCACAGGTTCAGGTGG	PKP4	ENSG00000144283	-0.805923548925297	[684]	[68,144]	-5	hSpCas9	negative selection	1385160
158533199	158533222	2	+	26627737	HeLa	viability after 8 days	GCAGGCCTCATTGGTGGAGGAGG	PKP4	ENSG00000144283	-0.16109110512992683	[366]	[224,114,108]	-1	hSpCas9	negative selection	1467472
158577362	158577385	2	+	26627737	HeLa	viability after 8 days	CACCAAGCATCGCCAGCACCAGG	PKP4	ENSG00000144283	-0.4172471137432881	[651]	[264,216,169]	-4	hSpCas9	negative selection	1467473
158624956	158624979	2	+	26627737	HeLa	viability after 8 days	ACAGGCGTGTCTCCTTCAAGGGG	PKP4	ENSG00000144283	1.1075293169985871	[314]	[353,279,266]	8	hSpCas9	negative selection	1467474
158631923	158631946	2	+	26627737	HeLa	viability after 8 days	TTGTATCGCACAGGTTCAGGTGG	PKP4	ENSG00000144283	-0.3962988042674193	[327]	[154,33,143]	-4	hSpCas9	negative selection	1467475
158533199	158533222	2	+	26627737	HeLa	viability after 12 days	GCAGGCCTCATTGGTGGAGGAGG	PKP4	ENSG00000144283	0.07795683985191523	[366]	[196,134,151]	0	hSpCas9	negative selection	1549787
158577362	158577385	2	+	26627737	HeLa	viability after 12 days	CACCAAGCATCGCCAGCACCAGG	PKP4	ENSG00000144283	0.2986876582082314	[651]	[339,260,400]	2	hSpCas9	negative selection	1549788
158624956	158624979	2	+	26627737	HeLa	viability after 12 days	ACAGGCGTGTCTCCTTCAAGGGG	PKP4	ENSG00000144283	1.0166568982199942	[314]	[411,229,155]	7	hSpCas9	negative selection	1549789
158631923	158631946	2	+	26627737	HeLa	viability after 12 days	TTGTATCGCACAGGTTCAGGTGG	PKP4	ENSG00000144283	-0.0635339537861872	[327]	[191,81,121]	0	hSpCas9	negative selection	1549790
158533199	158533222	2	+	26627737	HeLa	viability after 15 days	GCAGGCCTCATTGGTGGAGGAGG	PKP4	ENSG00000144283	-0.25870824101887835	[366]	[103,156,112]	-2	hSpCas9	negative selection	1632102
158577362	158577385	2	+	26627737	HeLa	viability after 15 days	CACCAAGCATCGCCAGCACCAGG	PKP4	ENSG00000144283	0.23012289392410046	[651]	[499,271,146]	2	hSpCas9	negative selection	1632103
158624956	158624979	2	+	26627737	HeLa	viability after 15 days	ACAGGCGTGTCTCCTTCAAGGGG	PKP4	ENSG00000144283	0.4002221277812427	[314]	[189,225,84]	3	hSpCas9	negative selection	1632104
158631923	158631946	2	+	26627737	HeLa	viability after 15 days	TTGTATCGCACAGGTTCAGGTGG	PKP4	ENSG00000144283	-0.16898732345939282	[327]	[89,131,135]	-1	hSpCas9	negative selection	1632105
158533199	158533222	2	+	26627737	HeLa	viability after 18 days	GCAGGCCTCATTGGTGGAGGAGG	PKP4	ENSG00000144283	-0.25740603335932444	[366]	[69,129,112]	-2	hSpCas9	negative selection	1714417
158577362	158577385	2	+	26627737	HeLa	viability after 18 days	CACCAAGCATCGCCAGCACCAGG	PKP4	ENSG00000144283	0.22949808660141457	[651]	[336,222,146]	2	hSpCas9	negative selection	1714418
158624956	158624979	2	+	26627737	HeLa	viability after 18 days	ACAGGCGTGTCTCCTTCAAGGGG	PKP4	ENSG00000144283	0.3256155503191511	[314]	[114,181,84]	2	hSpCas9	negative selection	1714419
158631923	158631946	2	+	26627737	HeLa	viability after 18 days	TTGTATCGCACAGGTTCAGGTGG	PKP4	ENSG00000144283	-0.1679048164106393	[327]	[59,109,135]	-1	hSpCas9	negative selection	1714420
158533199	158533222	2	+	26627737	HCT116	viability after 6 days	GCAGGCCTCATTGGTGGAGGAGG	PKP4	ENSG00000144283	-0.49422849349881265	[547]	[162,4]	-3	hSpCas9	negative selection	1796732
158577362	158577385	2	+	26627737	HCT116	viability after 6 days	CACCAAGCATCGCCAGCACCAGG	PKP4	ENSG00000144283	1.45594361572858	[1310]	[547,574]	7	hSpCas9	negative selection	1796733
158624956	158624979	2	+	26627737	HCT116	viability after 6 days	ACAGGCGTGTCTCCTTCAAGGGG	PKP4	ENSG00000144283	1.8734812539085919	[303]	[158,183]	8	hSpCas9	negative selection	1796734
158631923	158631946	2	+	26627737	HCT116	viability after 6 days	TTGTATCGCACAGGTTCAGGTGG	PKP4	ENSG00000144283	0.8569149058445036	[373]	[246,28]	5	hSpCas9	negative selection	1796735
158533199	158533222	2	+	26627737	HCT116	viability after 8 days	GCAGGCCTCATTGGTGGAGGAGG	PKP4	ENSG00000144283	-0.4463151075584967	[319]	[208,79,100]	-5	hSpCas9	negative selection	1879047
158577362	158577385	2	+	26627737	HCT116	viability after 8 days	CACCAAGCATCGCCAGCACCAGG	PKP4	ENSG00000144283	0.9124605302929301	[256]	[129,299,365]	8	hSpCas9	negative selection	1879048
158624956	158624979	2	+	26627737	HCT116	viability after 8 days	ACAGGCGTGTCTCCTTCAAGGGG	PKP4	ENSG00000144283	-0.20148021947289058	[419]	[197,225,179]	-2	hSpCas9	negative selection	1879049
158631923	158631946	2	+	26627737	HCT116	viability after 8 days	TTGTATCGCACAGGTTCAGGTGG	PKP4	ENSG00000144283	-0.7792129532756895	[295]	[78,124,80]	-7	hSpCas9	negative selection	1879050
158533199	158533222	2	+	26627737	HCT116	viability after 9 days	GCAGGCCTCATTGGTGGAGGAGG	PKP4	ENSG00000144283	0.2540037127103946	[547]	[164,181]	2	hSpCas9	negative selection	1961362
158577362	158577385	2	+	26627737	HCT116	viability after 9 days	CACCAAGCATCGCCAGCACCAGG	PKP4	ENSG00000144283	1.3360874907755713	[1310]	[613,1096]	8	hSpCas9	negative selection	1961363
158624956	158624979	2	+	26627737	HCT116	viability after 9 days	ACAGGCGTGTCTCCTTCAAGGGG	PKP4	ENSG00000144283	1.5610255437668785	[303]	[143,314]	8	hSpCas9	negative selection	1961364
158631923	158631946	2	+	26627737	HCT116	viability after 9 days	TTGTATCGCACAGGTTCAGGTGG	PKP4	ENSG00000144283	-0.7749877620890874	[373]	[73,45]	-5	hSpCas9	negative selection	1961365
158533199	158533222	2	+	26627737	HCT116	viability after 12 days	GCAGGCCTCATTGGTGGAGGAGG	PKP4	ENSG00000144283	0.12295210631549656	[319]	[164,183,201]	1	hSpCas9	negative selection	2043677
158577362	158577385	2	+	26627737	HCT116	viability after 12 days	CACCAAGCATCGCCAGCACCAGG	PKP4	ENSG00000144283	1.4649093196606378	[256]	[170,363,600]	9	hSpCas9	negative selection	2043678
158624956	158624979	2	+	26627737	HCT116	viability after 12 days	ACAGGCGTGTCTCCTTCAAGGGG	PKP4	ENSG00000144283	-0.11522285257924686	[419]	[55,231,336]	-1	hSpCas9	negative selection	2043679
158631923	158631946	2	+	26627737	HCT116	viability after 12 days	TTGTATCGCACAGGTTCAGGTGG	PKP4	ENSG00000144283	-0.09433155694162255	[295]	[154,173,107]	-1	hSpCas9	negative selection	2043680
158533199	158533222	2	+	26627737	HCT116	viability after 15 days	GCAGGCCTCATTGGTGGAGGAGG	PKP4	ENSG00000144283	-0.32116381705998087	[319]	[244,126,81]	-3	hSpCas9	negative selection	2125992
158577362	158577385	2	+	26627737	HCT116	viability after 15 days	CACCAAGCATCGCCAGCACCAGG	PKP4	ENSG00000144283	1.058799396753244	[256]	[337,270,316]	8	hSpCas9	negative selection	2125993
158624956	158624979	2	+	26627737	HCT116	viability after 15 days	ACAGGCGTGTCTCCTTCAAGGGG	PKP4	ENSG00000144283	0.024919521947380008	[419]	[116,225,375]	0	hSpCas9	negative selection	2125994
158631923	158631946	2	+	26627737	HCT116	viability after 15 days	TTGTATCGCACAGGTTCAGGTGG	PKP4	ENSG00000144283	-0.8557335904759444	[295]	[68,134,74]	-7	hSpCas9	negative selection	2125995
158533199	158533222	2	+	26627737	HCT116	viability after 18 days	GCAGGCCTCATTGGTGGAGGAGG	PKP4	ENSG00000144283	-0.21163817820790254	[319]	[272,65,62]	-2	hSpCas9	negative selection	2208307
158577362	158577385	2	+	26627737	HCT116	viability after 18 days	CACCAAGCATCGCCAGCACCAGG	PKP4	ENSG00000144283	1.9774547956364519	[256]	[509,410,554]	9	hSpCas9	negative selection	2208308
158624956	158624979	2	+	26627737	HCT116	viability after 18 days	ACAGGCGTGTCTCCTTCAAGGGG	PKP4	ENSG00000144283	-1.0562875327649541	[419]	[25,74,197]	-7	hSpCas9	negative selection	2208309
158631923	158631946	2	+	26627737	HCT116	viability after 18 days	TTGTATCGCACAGGTTCAGGTGG	PKP4	ENSG00000144283	-0.4899244994975969	[295]	[88,95,121]	-4	hSpCas9	negative selection	2208310
158484062	158484085	2	+	25494202	A375	resistance to PLX-4720 (puromycin)	TCTCGCTCTGTCGCCCAGGCCGG	PKP4	ENSG00000144283	-0.2966468943215429	[82,22]	[4,12]	-1	dCas9-VP64	positive selection	2413470
158495679	158495702	2	+	25494202	A375	resistance to PLX-4720 (puromycin)	CAAAAATTAGCTGGGCGTGGTAG	PKP4	ENSG00000144283	-0.7800023955638035	[210,54]	[8,23]	-4	dCas9-VP64	positive selection	2414199
158484062	158484085	2	+	25494202	A375	resistance to PLX-4720 (zeocin)	TCTCGCTCTGTCGCCCAGGCCGG	PKP4	ENSG00000144283	1.7427299536741634	[67,144]	[186,48]	8	dCas9-VP64	positive selection	2508725
158495679	158495702	2	+	25494202	A375	resistance to PLX-4720 (zeocin)	CAAAAATTAGCTGGGCGTGGTAG	PKP4	ENSG00000144283	7.182660032259671	[52,50]	[5183,10]	9	dCas9-VP64	positive selection	2509454
158621101	158621124	2	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	ACATCTCTCCATGAAAGTGAGGG	PKP4	ENSG00000144283	0.08385864385454031	[2,3]	[1,3]	1	hSpCas9	positive selection	3011633
158625114	158625137	2	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CCTCCCCAACAGCTATACGGCGG	PKP4	ENSG00000144283	0.09610648441296715	[4,4]	[2,5]	2	hSpCas9	positive selection	3011634
158625155	158625178	2	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CGGCAGACCTCCAATCCCAACGG	PKP4	ENSG00000144283	0.0059904340935214365	[3,3]	[2,3]	0	hSpCas9	positive selection	3011635
158631832	158631855	2	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TTACTCCTATATATGAGGGGAGG	PKP4	ENSG00000144283	0.06068712543477241	[3,3]	[3,2]	1	hSpCas9	positive selection	3011636
158621101	158621124	2	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	ACATCTCTCCATGAAAGTGAGGG	PKP4	ENSG00000144283	0.24855363700862815	[2,2]	[1,2]	4	hSpCas9	positive selection	3079491
158625114	158625137	2	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CCTCCCCAACAGCTATACGGCGG	PKP4	ENSG00000144283	-0.5124490482645184	[4,4]	[3,0]	-7	hSpCas9	positive selection	3079492
158625155	158625178	2	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CGGCAGACCTCCAATCCCAACGG	PKP4	ENSG00000144283	-0.3541153820812954	[3,3]	[4,0]	-5	hSpCas9	positive selection	3079493
158631832	158631855	2	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TTACTCCTATATATGAGGGGAGG	PKP4	ENSG00000144283	-0.159999472233053	[3,3]	[2,1]	-2	hSpCas9	positive selection	3079494
158533303	158533326		-	24336571	A375	resistance to PLX after 7 days	AGGATGTACCTGCTCCTTCACGG	PKP4	ENSG00000144283	-0.04901140190984887	[40,37]	[39,35]	-1	hSpCas9	positive selection	3135904
158533289	158533312		+	24336571	A375	resistance to PLX after 7 days	CACTATTCTAGCATCCGTGAAGG	PKP4	ENSG00000144283	-0.2125694259683315	[19,19]	[17,16]	-6	hSpCas9	positive selection	3135905
158642578	158642601		-	24336571	A375	resistance to PLX after 7 days	CTGTAGACTTGCCAAAAACGAGG	PKP4	ENSG00000144283	0.0789225261592838	[10,11]	[12,11]	2	hSpCas9	positive selection	3135907
158642567	158642590		+	24336571	A375	resistance to PLX after 7 days	GCCCTTCGAAACCTCGTTTTTGG	PKP4	ENSG00000144283	-0.3272338473454175	[51,51]	[39,40]	-8	hSpCas9	positive selection	3135908
158533220	158533243		+	24336571	A375	resistance to PLX after 7 days	GGGGCAACCACAGACCCGCCAGG	PKP4	ENSG00000144283	-0.013479414031552395	[12,9]	[11,10]	0	hSpCas9	positive selection	3135909
158642477	158642500		+	24336571	A375	resistance to PLX after 7 days	TCATTCTAGGTGTGTAGGTTAGG	PKP4	ENSG00000144283	-0.1527699616366931	[33,28]	[27,27]	-5	hSpCas9	positive selection	3135910
158533303	158533326		-	24336571	A375	resistance to PLX after 14 days	AGGATGTACCTGCTCCTTCACGG	PKP4	ENSG00000144283	-0.07306019624661708	[42,27]	[16,13]	0	hSpCas9	positive selection	3193697
158533289	158533312		+	24336571	A375	resistance to PLX after 14 days	CACTATTCTAGCATCCGTGAAGG	PKP4	ENSG00000144283	0.16861023389116186	[13,19]	[6,10]	1	hSpCas9	positive selection	3193698
158642578	158642601		-	24336571	A375	resistance to PLX after 14 days	CTGTAGACTTGCCAAAAACGAGG	PKP4	ENSG00000144283	-0.0066846877443922925	[7,10]	[3,4]	0	hSpCas9	positive selection	3193700
158642567	158642590		+	24336571	A375	resistance to PLX after 14 days	GCCCTTCGAAACCTCGTTTTTGG	PKP4	ENSG00000144283	-1.4012828115625309	[68,50]	[11,8]	-9	hSpCas9	positive selection	3193701
158533220	158533243		+	24336571	A375	resistance to PLX after 14 days	GGGGCAACCACAGACCCGCCAGG	PKP4	ENSG00000144283	0.8972178185335904	[8,11]	[7,9]	7	hSpCas9	positive selection	3193702
158642477	158642500		+	24336571	A375	resistance to PLX after 14 days	TCATTCTAGGTGTGTAGGTTAGG	PKP4	ENSG00000144283	-0.3977816668393618	[21,30]	[8,8]	-5	hSpCas9	positive selection	3193703
158533303	158533326		-	24336571	A375	viability after 7 days	AGGATGTACCTGCTCCTTCACGG	PKP4	ENSG00000144283	0.4192481509563797	[30]	[40,37]	6	hSpCas9	negative selection	3251490
158533289	158533312		+	24336571	A375	viability after 7 days	CACTATTCTAGCATCCGTGAAGG	PKP4	ENSG00000144283	-0.20476868126085068	[23]	[19,19]	-3	hSpCas9	negative selection	3251491
158642578	158642601		-	24336571	A375	viability after 7 days	CTGTAGACTTGCCAAAAACGAGG	PKP4	ENSG00000144283	0.33333174855425796	[9]	[10,11]	5	hSpCas9	negative selection	3251493
158642567	158642590		+	24336571	A375	viability after 7 days	GCCCTTCGAAACCTCGTTTTTGG	PKP4	ENSG00000144283	0.4298453168439311	[39]	[51,51]	6	hSpCas9	negative selection	3251494
158533220	158533243		+	24336571	A375	viability after 7 days	GGGGCAACCACAGACCCGCCAGG	PKP4	ENSG00000144283	-0.0788782531850985	[12]	[12,9]	-1	hSpCas9	negative selection	3251495
158642477	158642500		+	24336571	A375	viability after 7 days	TCATTCTAGGTGTGTAGGTTAGG	PKP4	ENSG00000144283	0.6116243250683422	[20]	[33,28]	8	hSpCas9	negative selection	3251496
158533303	158533326		-	24336571	A375	viability after 14 days	AGGATGTACCTGCTCCTTCACGG	PKP4	ENSG00000144283	0.2864163403963398	[30]	[42,27]	4	hSpCas9	negative selection	3309283
158533289	158533312		+	24336571	A375	viability after 14 days	CACTATTCTAGCATCCGTGAAGG	PKP4	ENSG00000144283	-0.4325576240247528	[23]	[13,19]	-5	hSpCas9	negative selection	3309284
158642578	158642601		-	24336571	A375	viability after 14 days	CTGTAGACTTGCCAAAAACGAGG	PKP4	ENSG00000144283	0.10346608329898438	[9]	[7,10]	1	hSpCas9	negative selection	3309286
158642567	158642590		+	24336571	A375	viability after 14 days	GCCCTTCGAAACCTCGTTTTTGG	PKP4	ENSG00000144283	0.6613844812722098	[39]	[68,50]	8	hSpCas9	negative selection	3309287
158533220	158533243		+	24336571	A375	viability after 14 days	GGGGCAACCACAGACCCGCCAGG	PKP4	ENSG00000144283	-0.22485785957396504	[12]	[8,11]	-3	hSpCas9	negative selection	3309288
158642477	158642500		+	24336571	A375	viability after 14 days	TCATTCTAGGTGTGTAGGTTAGG	PKP4	ENSG00000144283	0.3982825594746431	[20]	[21,30]	5	hSpCas9	negative selection	3309289
158642477	158642500	2	+	27383988	293T	resistance to West Nile virus (flavivirus)	TCATTCTAGGTGTGTAGGTTAGG	PKP4	ENSG00000144283	1.399345216318263	[57,57]	[0,0]	6	hSpCas9	positive selection	3386085
158621100	158621123	2	+	26780180	HT29	viability (Avana library 4 designs)	ACATCTCTCCATGAAAGTGAGGG	PKP4	ENSG00000144283	0.747258070391294	[]	[]	3	hSpCas9	negative selection	3449724
158625113	158625136	2	+	26780180	HT29	viability (Avana library 4 designs)	CCTCCCCAACAGCTATACGGCGG	PKP4	ENSG00000144283	1.20365746369716	[]	[]	5	hSpCas9	negative selection	3449725
158625154	158625177	2	+	26780180	HT29	viability (Avana library 4 designs)	CGGCAGACCTCCAATCCCAACGG	PKP4	ENSG00000144283	0.29133765892433	[]	[]	1	hSpCas9	negative selection	3449726
158631831	158631854	2	+	26780180	HT29	viability (Avana library 4 designs)	TTACTCCTATATATGAGGGGAGG	PKP4	ENSG00000144283	0.471988877248178	[]	[]	1	hSpCas9	negative selection	3449727
158625113	158625136	2	+	26780180	A375	viability (Avana lentiCRISPRv2)	CCTCCCCAACAGCTATACGGCGG	PKP4	ENSG00000144283	-2.11286467169176	[]	[]	-3	hSpCas9	negative selection	3544622
158621100	158621123	2	+	26780180	A375	viability (Avana lentiCRISPRv2)	ACATCTCTCCATGAAAGTGAGGG	PKP4	ENSG00000144283	-6.78193062028361	[]	[]	-6	hSpCas9	negative selection	3544623
158631831	158631854	2	+	26780180	A375	viability (Avana lentiCRISPRv2)	TTACTCCTATATATGAGGGGAGG	PKP4	ENSG00000144283	-7.01860169287074	[]	[]	-6	hSpCas9	negative selection	3544624
158625154	158625177	2	+	26780180	A375	viability (Avana lentiCRISPRv2)	CGGCAGACCTCCAATCCCAACGG	PKP4	ENSG00000144283	-0.0173635828650371	[]	[]	0	hSpCas9	negative selection	3544625
158625182	158625205	2	-	26780180	A375	viability (Avana lentiCRISPRv2)	GGCGGTGGTTTGGTATTGAGGGG	PKP4	ENSG00000144283	2.4492250542478	[]	[]	3	hSpCas9	negative selection	3544626
158634143	158634166	2	+	26780180	A375	viability (Avana lentiCRISPRv2)	GAACACAACAGCTACCTACGCGG	PKP4	ENSG00000144283	0.732575532346261	[]	[]	1	hSpCas9	negative selection	3544627
158625113	158625136	2	+	26780180	A375	viability (Avana lentiGuide)	CCTCCCCAACAGCTATACGGCGG	PKP4	ENSG00000144283	-3.00511492694041	[]	[]	-5	hSpCas9	negative selection	3653281
158621100	158621123	2	+	26780180	A375	viability (Avana lentiGuide)	ACATCTCTCCATGAAAGTGAGGG	PKP4	ENSG00000144283	2.63656015072585	[]	[]	3	hSpCas9	negative selection	3653282
158631831	158631854	2	+	26780180	A375	viability (Avana lentiGuide)	TTACTCCTATATATGAGGGGAGG	PKP4	ENSG00000144283	3.63310476101481	[]	[]	3	hSpCas9	negative selection	3653283
158625154	158625177	2	+	26780180	A375	viability (Avana lentiGuide)	CGGCAGACCTCCAATCCCAACGG	PKP4	ENSG00000144283	-1.5652793318091	[]	[]	-3	hSpCas9	negative selection	3653284
158625182	158625205	2	-	26780180	A375	viability (Avana lentiGuide)	GGCGGTGGTTTGGTATTGAGGGG	PKP4	ENSG00000144283	-4.31867633351071	[]	[]	-7	hSpCas9	negative selection	3653285
158634143	158634166	2	+	26780180	A375	viability (Avana lentiGuide)	GAACACAACAGCTACCTACGCGG	PKP4	ENSG00000144283	-3.06559918210557	[]	[]	-5	hSpCas9	negative selection	3653286
158625113	158625136	2	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CCTCCCCAACAGCTATACGGCGG	PKP4	ENSG00000144283	-0.06496928483169623	[5]	[5,4]	-1	hSpCas9	positive selection	3761940
158621100	158621123	2	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ACATCTCTCCATGAAAGTGAGGG	PKP4	ENSG00000144283	-0.3324318477041915	[5]	[4,3]	-5	hSpCas9	positive selection	3761941
158631831	158631854	2	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TTACTCCTATATATGAGGGGAGG	PKP4	ENSG00000144283	-0.42426141601859085	[7]	[5,5]	-6	hSpCas9	positive selection	3761942
158625154	158625177	2	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CGGCAGACCTCCAATCCCAACGG	PKP4	ENSG00000144283	0.19824396344188844	[4]	[5,5]	5	hSpCas9	positive selection	3761943
158625182	158625205	2	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGCGGTGGTTTGGTATTGAGGGG	PKP4	ENSG00000144283	0.43479788764557503	[4]	[6,5]	9	hSpCas9	positive selection	3761944
158634143	158634166	2	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GAACACAACAGCTACCTACGCGG	PKP4	ENSG00000144283	0.21773594117439543	[4]	[4,5]	6	hSpCas9	positive selection	3761945
158625113	158625136	2	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CCTCCCCAACAGCTATACGGCGG	PKP4	ENSG00000144283	0.2042084531848686	[6]	[6,5]	5	hSpCas9	positive selection	3870547
158621100	158621123	2	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ACATCTCTCCATGAAAGTGAGGG	PKP4	ENSG00000144283	-1.0274436029714973	[4]	[1,1]	-8	hSpCas9	positive selection	3870548
158631831	158631854	2	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TTACTCCTATATATGAGGGGAGG	PKP4	ENSG00000144283	-0.24814144516842773	[5]	[1,5]	-3	hSpCas9	positive selection	3870549
158625154	158625177	2	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CGGCAGACCTCCAATCCCAACGG	PKP4	ENSG00000144283	0.3186223160032839	[5]	[5,5]	8	hSpCas9	positive selection	3870550
158625182	158625205	2	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGCGGTGGTTTGGTATTGAGGGG	PKP4	ENSG00000144283	0.33414940839988827	[5]	[4,6]	8	hSpCas9	positive selection	3870551
158634143	158634166	2	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GAACACAACAGCTACCTACGCGG	PKP4	ENSG00000144283	0.21458347008801104	[5]	[5,5]	5	hSpCas9	positive selection	3870552
158533289	158533312	2	+	26780180	A375	viability	CACTATTCTAGCATCCGTGAAGG	PKP4	ENSG00000144283	1.38992495657761	[]	[]	7	hSpCas9	negative selection	3981364
158642578	158642601	2	-	26780180	A375	viability	CTGTAGACTTGCCAAAAACGAGG	PKP4	ENSG00000144283	1.01263671129296	[]	[]	5	hSpCas9	negative selection	3981365
158533220	158533243	2	+	26780180	A375	viability	GGGGCAACCACAGACCCGCCAGG	PKP4	ENSG00000144283	0.413312220316541	[]	[]	1	hSpCas9	negative selection	3981366
158642477	158642500	2	+	26780180	A375	viability	TCATTCTAGGTGTGTAGGTTAGG	PKP4	ENSG00000144283	0.957459773861432	[]	[]	4	hSpCas9	negative selection	3981367
158533289	158533312	2	+	26780180	HT29	viability (GeCKOv2 library)	CACTATTCTAGCATCCGTGAAGG	PKP4	ENSG00000144283	1.90021527807843	[]	[]	9	hSpCas9	negative selection	4089330
158642578	158642601	2	-	26780180	HT29	viability (GeCKOv2 library)	CTGTAGACTTGCCAAAAACGAGG	PKP4	ENSG00000144283	1.60080082202244	[]	[]	8	hSpCas9	negative selection	4089331
158533220	158533243	2	+	26780180	HT29	viability (GeCKOv2 library)	GGGGCAACCACAGACCCGCCAGG	PKP4	ENSG00000144283	0.479518387640217	[]	[]	1	hSpCas9	negative selection	4089332
158642477	158642500	2	+	26780180	HT29	viability (GeCKOv2 library)	TCATTCTAGGTGTGTAGGTTAGG	PKP4	ENSG00000144283	0.935732349714065	[]	[]	4	hSpCas9	negative selection	4089333
158533303	158533326	2	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	AGGATGTACCTGCTCCTTCACGG	PKP4	ENSG00000144283	0.1643302096704638	[5]	[3,3]	4	hSpCas9	positive selection	4160883
158533289	158533312	2	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CACTATTCTAGCATCCGTGAAGG	PKP4	ENSG00000144283	0.08828913562051577	[4]	[2,2]	2	hSpCas9	positive selection	4160884
158642578	158642601	2	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CTGTAGACTTGCCAAAAACGAGG	PKP4	ENSG00000144283	-0.20807948544745392	[3]	[1,1]	-5	hSpCas9	positive selection	4160886
158642567	158642590	2	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GCCCTTCGAAACCTCGTTTTTGG	PKP4	ENSG00000144283	0.18773884593999474	[5]	[4,3]	5	hSpCas9	positive selection	4160887
158533220	158533243	2	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GGGGCAACCACAGACCCGCCAGG	PKP4	ENSG00000144283	0.10579876870330127	[4]	[2,3]	2	hSpCas9	positive selection	4160888
158642477	158642500	2	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TCATTCTAGGTGTGTAGGTTAGG	PKP4	ENSG00000144283	0.21781179621248492	[4]	[4,3]	5	hSpCas9	positive selection	4160889
158533303	158533326	2	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	AGGATGTACCTGCTCCTTCACGG	PKP4	ENSG00000144283	0.8619518226456818	[5]	[4,4,5,3]	5	hSpCas9	positive selection	4224905
158533289	158533312	2	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CACTATTCTAGCATCCGTGAAGG	PKP4	ENSG00000144283	-0.2359983037416439	[3]	[0,2,1,0]	-3	hSpCas9	positive selection	4224906
158642578	158642601	2	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CTGTAGACTTGCCAAAAACGAGG	PKP4	ENSG00000144283	-0.06163535314583577	[3]	[3,0,1,0]	-1	hSpCas9	positive selection	4224908
158642567	158642590	2	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GCCCTTCGAAACCTCGTTTTTGG	PKP4	ENSG00000144283	0.32751308661250667	[5]	[4,4,4,0]	2	hSpCas9	positive selection	4224909
158533220	158533243	2	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GGGGCAACCACAGACCCGCCAGG	PKP4	ENSG00000144283	0.5169637891825182	[4]	[0,0,2,3]	3	hSpCas9	positive selection	4224910
158642477	158642500	2	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TCATTCTAGGTGTGTAGGTTAGG	PKP4	ENSG00000144283	0.9988151567932478	[4]	[0,3,4,4]	7	hSpCas9	positive selection	4224911
158533220	158533243	2	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GGGGCAACCACAGACCCGCCAGG	PKP4	ENSG00000144283	0.3059706018600046	[1]	[1,0]	6	hSpCas9	positive selection	4290510
158642578	158642601	2	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CTGTAGACTTGCCAAAAACGAGG	PKP4	ENSG00000144283	0.09866395576308815	[2]	[2,1]	2	hSpCas9	positive selection	4290511
158533289	158533312	2	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CACTATTCTAGCATCCGTGAAGG	PKP4	ENSG00000144283	0.06837803669367751	[2]	[2,1]	1	hSpCas9	positive selection	4290512
158642477	158642500	2	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TCATTCTAGGTGTGTAGGTTAGG	PKP4	ENSG00000144283	-0.3471860776801047	[1]	[1,0]	-6	hSpCas9	positive selection	4354762
158625119	158625141	2	+	27760321	OCIAML3	viability	CAACAGCTATACGGCGGATTGG	PKP4	ENSG00000144283	0.49460678041718775	[751,568]	[536,962]	6	hSpCas9	negative selection	4428191
158625225	158625247	2	-	27760321	OCIAML3	viability	TCGAGTCTGTGCATCCGTCAGG	PKP4	ENSG00000144283	-0.26159409225684427	[1974,1733]	[1087,1362]	-3	hSpCas9	negative selection	4428192
158625278	158625300	2	+	27760321	OCIAML3	viability	CGTCGTCCCCCAAACGCTCAGG	PKP4	ENSG00000144283	-0.06524381512751154	[831,692]	[521,626]	0	hSpCas9	negative selection	4428193
158631915	158631937	2	+	27760321	OCIAML3	viability	AGACGGCGTTGTATCGCACAGG	PKP4	ENSG00000144283	-0.04763772264635907	[646,453]	[338,506]	0	hSpCas9	negative selection	4428194
158634155	158634177	2	+	27760321	OCIAML3	viability	TACCTACGCGGAGCCCTACAGG	PKP4	ENSG00000144283	-0.1713464575396785	[437,334]	[225,318]	-2	hSpCas9	negative selection	4428195
158625119	158625141	2	+	27760321	OCIAML2	viability	CAACAGCTATACGGCGGATTGG	PKP4	ENSG00000144283	0.690180900056239	[751,568]	[729,1019]	8	hSpCas9	negative selection	4511654
158625225	158625247	2	-	27760321	OCIAML2	viability	TCGAGTCTGTGCATCCGTCAGG	PKP4	ENSG00000144283	-0.057756331927109716	[1974,1733]	[1276,1650]	0	hSpCas9	negative selection	4511655
158625278	158625300	2	+	27760321	OCIAML2	viability	CGTCGTCCCCCAAACGCTCAGG	PKP4	ENSG00000144283	0.020870189855521026	[831,692]	[573,687]	0	hSpCas9	negative selection	4511656
158631915	158631937	2	+	27760321	OCIAML2	viability	AGACGGCGTTGTATCGCACAGG	PKP4	ENSG00000144283	-0.4251720087439293	[646,453]	[226,460]	-5	hSpCas9	negative selection	4511657
158634155	158634177	2	+	27760321	OCIAML2	viability	TACCTACGCGGAGCCCTACAGG	PKP4	ENSG00000144283	-0.012018347281183867	[437,334]	[226,413]	0	hSpCas9	negative selection	4511658
158625119	158625141	2	+	27760321	MV411	viability	CAACAGCTATACGGCGGATTGG	PKP4	ENSG00000144283	-0.06039141177465268	[751,568]	[191,748]	0	hSpCas9	negative selection	4595117
158625225	158625247	2	-	27760321	MV411	viability	TCGAGTCTGTGCATCCGTCAGG	PKP4	ENSG00000144283	-0.0930041980939802	[1974,1733]	[459,2173]	0	hSpCas9	negative selection	4595118
158625278	158625300	2	+	27760321	MV411	viability	CGTCGTCCCCCAAACGCTCAGG	PKP4	ENSG00000144283	-0.1841566753278192	[831,692]	[460,410]	-1	hSpCas9	negative selection	4595119
158631915	158631937	2	+	27760321	MV411	viability	AGACGGCGTTGTATCGCACAGG	PKP4	ENSG00000144283	-1.2655835282409156	[646,453]	[172,113]	-7	hSpCas9	negative selection	4595120
158634155	158634177	2	+	27760321	MV411	viability	TACCTACGCGGAGCCCTACAGG	PKP4	ENSG00000144283	0.42816385284710007	[437,334]	[39,791]	3	hSpCas9	negative selection	4595121
158625119	158625141	2	+	27760321	HL60	viability	CAACAGCTATACGGCGGATTGG	PKP4	ENSG00000144283	0.2768530353032075	[751,568]	[727,563]	3	hSpCas9	negative selection	4678580
158625225	158625247	2	-	27760321	HL60	viability	TCGAGTCTGTGCATCCGTCAGG	PKP4	ENSG00000144283	-0.4009667811452524	[1974,1733]	[1126,1163]	-4	hSpCas9	negative selection	4678581
158625278	158625300	2	+	27760321	HL60	viability	CGTCGTCCCCCAAACGCTCAGG	PKP4	ENSG00000144283	-0.6201639159048549	[831,692]	[354,454]	-6	hSpCas9	negative selection	4678582
158631915	158631937	2	+	27760321	HL60	viability	AGACGGCGTTGTATCGCACAGG	PKP4	ENSG00000144283	-0.5075861408870005	[646,453]	[272,354]	-5	hSpCas9	negative selection	4678583
158634155	158634177	2	+	27760321	HL60	viability	TACCTACGCGGAGCCCTACAGG	PKP4	ENSG00000144283	0.13144249310806844	[437,334]	[332,353]	1	hSpCas9	negative selection	4678584
158625119	158625141	2	+	27760321	HT1080	viability	CAACAGCTATACGGCGGATTGG	PKP4	ENSG00000144283	-0.0556097433453302	[568,443]	[154,236]	0	hSpCas9	negative selection	4762043
158625225	158625247	2	-	27760321	HT1080	viability	TCGAGTCTGTGCATCCGTCAGG	PKP4	ENSG00000144283	1.2375298245358208	[1733,1352]	[1435,1464]	6	hSpCas9	negative selection	4762044
158625278	158625300	2	+	27760321	HT1080	viability	CGTCGTCCCCCAAACGCTCAGG	PKP4	ENSG00000144283	0.6801450442154223	[692,540]	[242,558]	3	hSpCas9	negative selection	4762045
158631915	158631937	2	+	27760321	HT1080	viability	AGACGGCGTTGTATCGCACAGG	PKP4	ENSG00000144283	-0.6336949029516785	[453,353]	[118,86]	-3	hSpCas9	negative selection	4762046
158634155	158634177	2	+	27760321	HT1080	viability	TACCTACGCGGAGCCCTACAGG	PKP4	ENSG00000144283	0.46699436852204146	[334,261]	[161,166]	2	hSpCas9	negative selection	4762047
158625119	158625141	2	+	27760321	HT29	viability after 7 days	CAACAGCTATACGGCGGATTGG	PKP4	ENSG00000144283	0.5372221954218419	[568,443]	[1043,960,845]	7	hSpCas9	negative selection	4845506
158625225	158625247	2	-	27760321	HT29	viability after 7 days	TCGAGTCTGTGCATCCGTCAGG	PKP4	ENSG00000144283	-0.4674673275660375	[1733,1352]	[1966,1312,1109]	-6	hSpCas9	negative selection	4845507
158625278	158625300	2	+	27760321	HT29	viability after 7 days	CGTCGTCCCCCAAACGCTCAGG	PKP4	ENSG00000144283	0.15462359486540755	[692,540]	[1054,817,801]	2	hSpCas9	negative selection	4845508
158631915	158631937	2	+	27760321	HT29	viability after 7 days	AGACGGCGTTGTATCGCACAGG	PKP4	ENSG00000144283	-0.4516492815768044	[453,353]	[679,292,213]	-6	hSpCas9	negative selection	4845509
158634155	158634177	2	+	27760321	HT29	viability after 7 days	TACCTACGCGGAGCCCTACAGG	PKP4	ENSG00000144283	0.012620969427831641	[334,261]	[499,348,329]	0	hSpCas9	negative selection	4845510
158625119	158625141	2	+	27760321	HT29	viability after 25 days	CAACAGCTATACGGCGGATTGG	PKP4	ENSG00000144283	0.4900198381737985	[568,443]	[777,967,679]	5	hSpCas9	negative selection	4928969
158625225	158625247	2	-	27760321	HT29	viability after 25 days	TCGAGTCTGTGCATCCGTCAGG	PKP4	ENSG00000144283	-0.29712425833905676	[1733,1352]	[1404,1470,1429]	-3	hSpCas9	negative selection	4928970
158625278	158625300	2	+	27760321	HT29	viability after 25 days	CGTCGTCCCCCAAACGCTCAGG	PKP4	ENSG00000144283	0.08395742376069282	[692,540]	[641,751,865]	0	hSpCas9	negative selection	4928971
158631915	158631937	2	+	27760321	HT29	viability after 25 days	AGACGGCGTTGTATCGCACAGG	PKP4	ENSG00000144283	-0.017055441825976708	[453,353]	[373,432,578]	0	hSpCas9	negative selection	4928972
158634155	158634177	2	+	27760321	HT29	viability after 25 days	TACCTACGCGGAGCCCTACAGG	PKP4	ENSG00000144283	-0.03213706908047981	[334,261]	[321,355,321]	0	hSpCas9	negative selection	4928973
158625119	158625141	2	+	27760321	HT29	viability after 22 days	CAACAGCTATACGGCGGATTGG	PKP4	ENSG00000144283	0.8647268486200037	[568,443]	[1486,773,924]	8	hSpCas9	negative selection	5012432
158625225	158625247	2	-	27760321	HT29	viability after 22 days	TCGAGTCTGTGCATCCGTCAGG	PKP4	ENSG00000144283	-0.38040483134140923	[1733,1352]	[1150,1301,1667]	-4	hSpCas9	negative selection	5012433
158625278	158625300	2	+	27760321	HT29	viability after 22 days	CGTCGTCCCCCAAACGCTCAGG	PKP4	ENSG00000144283	-0.15957464091514395	[692,540]	[569,566,781]	-2	hSpCas9	negative selection	5012434
158631915	158631937	2	+	27760321	HT29	viability after 22 days	AGACGGCGTTGTATCGCACAGG	PKP4	ENSG00000144283	0.08498423328733443	[453,353]	[477,461,546]	0	hSpCas9	negative selection	5012435
158634155	158634177	2	+	27760321	HT29	viability after 22 days	TACCTACGCGGAGCCCTACAGG	PKP4	ENSG00000144283	-0.0594955167026332	[334,261]	[397,233,359]	0	hSpCas9	negative selection	5012436
158625119	158625141	2	+	27760321	HT29	viability after 19 days	CAACAGCTATACGGCGGATTGG	PKP4	ENSG00000144283	0.8947293389539557	[568,443]	[1258,1493,517]	8	hSpCas9	negative selection	5095895
158625225	158625247	2	-	27760321	HT29	viability after 19 days	TCGAGTCTGTGCATCCGTCAGG	PKP4	ENSG00000144283	-0.31757064116881883	[1733,1352]	[1557,1737,983]	-3	hSpCas9	negative selection	5095896
158625278	158625300	2	+	27760321	HT29	viability after 19 days	CGTCGTCCCCCAAACGCTCAGG	PKP4	ENSG00000144283	-0.0519704149356508	[692,540]	[1118,488,486]	0	hSpCas9	negative selection	5095897
158631915	158631937	2	+	27760321	HT29	viability after 19 days	AGACGGCGTTGTATCGCACAGG	PKP4	ENSG00000144283	-0.4963092575817897	[453,353]	[457,289,250]	-4	hSpCas9	negative selection	5095898
158634155	158634177	2	+	27760321	HT29	viability after 19 days	TACCTACGCGGAGCCCTACAGG	PKP4	ENSG00000144283	0.9344228515832687	[334,261]	[548,656,736]	8	hSpCas9	negative selection	5095899
158625119	158625141	2	+	27760321	HT29	viability after 16 days	CAACAGCTATACGGCGGATTGG	PKP4	ENSG00000144283	0.7374366740235594	[568,443]	[1120,973,754]	8	hSpCas9	negative selection	5179358
158625225	158625247	2	-	27760321	HT29	viability after 16 days	TCGAGTCTGTGCATCCGTCAGG	PKP4	ENSG00000144283	-0.6216172436332208	[1733,1352]	[1356,1123,907]	-5	hSpCas9	negative selection	5179359
158625278	158625300	2	+	27760321	HT29	viability after 16 days	CGTCGTCCCCCAAACGCTCAGG	PKP4	ENSG00000144283	-0.2584803711029682	[692,540]	[596,424,714]	-3	hSpCas9	negative selection	5179360
158631915	158631937	2	+	27760321	HT29	viability after 16 days	AGACGGCGTTGTATCGCACAGG	PKP4	ENSG00000144283	0.0177604850332293	[453,353]	[416,449,501]	0	hSpCas9	negative selection	5179361
158634155	158634177	2	+	27760321	HT29	viability after 16 days	TACCTACGCGGAGCCCTACAGG	PKP4	ENSG00000144283	0.04275196613043017	[334,261]	[374,344,314]	0	hSpCas9	negative selection	5179362
158625119	158625141	2	+	27760321	HT29	viability after 13 days	CAACAGCTATACGGCGGATTGG	PKP4	ENSG00000144283	0.5794758025376705	[568,443]	[871,986,780]	7	hSpCas9	negative selection	5262821
158625225	158625247	2	-	27760321	HT29	viability after 13 days	TCGAGTCTGTGCATCCGTCAGG	PKP4	ENSG00000144283	-0.6764314669211307	[1733,1352]	[1059,1297,1009]	-6	hSpCas9	negative selection	5262822
158625278	158625300	2	+	27760321	HT29	viability after 13 days	CGTCGTCCCCCAAACGCTCAGG	PKP4	ENSG00000144283	-0.07809748900735047	[692,540]	[594,721,714]	-1	hSpCas9	negative selection	5262823
158631915	158631937	2	+	27760321	HT29	viability after 13 days	AGACGGCGTTGTATCGCACAGG	PKP4	ENSG00000144283	-0.4114997084016715	[453,353]	[226,489,340]	-5	hSpCas9	negative selection	5262824
158634155	158634177	2	+	27760321	HT29	viability after 13 days	TACCTACGCGGAGCCCTACAGG	PKP4	ENSG00000144283	0.029808455139559348	[334,261]	[366,414,282]	0	hSpCas9	negative selection	5262825
158625119	158625141	2	+	27760321	HT29	viability after 10 days	CAACAGCTATACGGCGGATTGG	PKP4	ENSG00000144283	0.8148329193576287	[568,443]	[1264,921,1143]	9	hSpCas9	negative selection	5346284
158625225	158625247	2	-	27760321	HT29	viability after 10 days	TCGAGTCTGTGCATCCGTCAGG	PKP4	ENSG00000144283	-0.29442806910025854	[1733,1352]	[1805,1529,1380]	-4	hSpCas9	negative selection	5346285
158625278	158625300	2	+	27760321	HT29	viability after 10 days	CGTCGTCCCCCAAACGCTCAGG	PKP4	ENSG00000144283	0.0691026724025583	[692,540]	[616,765,1034]	0	hSpCas9	negative selection	5346286
158631915	158631937	2	+	27760321	HT29	viability after 10 days	AGACGGCGTTGTATCGCACAGG	PKP4	ENSG00000144283	0.07370666886470184	[453,353]	[536,399,648]	0	hSpCas9	negative selection	5346287
158634155	158634177	2	+	27760321	HT29	viability after 10 days	TACCTACGCGGAGCCCTACAGG	PKP4	ENSG00000144283	-0.08744101116925979	[334,261]	[220,500,334]	-1	hSpCas9	negative selection	5346288
158625119	158625141	2	+	27760321	MOLM13	viability	CAACAGCTATACGGCGGATTGG	PKP4	ENSG00000144283	1.0583103836884402	[751,568]	[550,955]	7	hSpCas9	negative selection	5429747
158625225	158625247	2	-	27760321	MOLM13	viability	TCGAGTCTGTGCATCCGTCAGG	PKP4	ENSG00000144283	0.31832801191585913	[1974,1733]	[1100,1472]	2	hSpCas9	negative selection	5429748
158625278	158625300	2	+	27760321	MOLM13	viability	CGTCGTCCCCCAAACGCTCAGG	PKP4	ENSG00000144283	0.38090656882601936	[831,692]	[976,200]	2	hSpCas9	negative selection	5429749
158631915	158631937	2	+	27760321	MOLM13	viability	AGACGGCGTTGTATCGCACAGG	PKP4	ENSG00000144283	-1.0444781350218393	[646,453]	[55,227]	-6	hSpCas9	negative selection	5429750
158634155	158634177	2	+	27760321	MOLM13	viability	TACCTACGCGGAGCCCTACAGG	PKP4	ENSG00000144283	-0.901347871160644	[437,334]	[137,96]	-5	hSpCas9	negative selection	5429751
158456981	158457004	2	+	27661255	K562	viability	GTCGACGCCGGCCGCGGAGGCGG	PKP4	ENSG00000144283	0.15650372397022513	[661,658]	[606,571]	5	dCas9-KRAB	negative selection	5502227
158456996	158457019	2	+	27661255	K562	viability	GGAGGCGGCACCATGGGCAAGGG	PKP4	ENSG00000144283	0.21295323840955627	[1908,2089]	[1885,1815]	7	dCas9-KRAB	negative selection	5502228
158456943	158456966	2	-	27661255	K562	viability	GAGCCCCCTCTACTGCCCAGAGG	PKP4	ENSG00000144283	0.04864410673077513	[1226,1012]	[1022,847]	1	dCas9-KRAB	negative selection	5502229
158457045	158457068	2	-	27661255	K562	viability	GGCTCTCCCACCACCCCCGGCGG	PKP4	ENSG00000144283	0.10830442243046323	[186,378]	[291,196]	4	dCas9-KRAB	negative selection	5502230
158457258	158457281	2	-	27661255	K562	viability	GCGAGGGCCGAGGGTCTCGTGGG	PKP4	ENSG00000144283	0.2621538384649382	[747,879]	[817,742]	8	dCas9-KRAB	negative selection	5502231
158457366	158457389	2	-	27661255	K562	viability	GAGGCGGGGCAGGAAAGCCGCGG	PKP4	ENSG00000144283	0.6022015507819617	[690,737]	[954,788]	9	dCas9-KRAB	negative selection	5502232
158457382	158457405	2	-	27661255	K562	viability	GTGCGGGCAGGAACACGAGGCGG	PKP4	ENSG00000144283	-0.01684522747163375	[1799,1666]	[1626,1151]	0	dCas9-KRAB	negative selection	5502233
158457398	158457421	2	-	27661255	K562	viability	GGGGAGCAGCAGGCGAGTGCGGG	PKP4	ENSG00000144283	0.08047704215173013	[1228,1098]	[1084,899]	3	dCas9-KRAB	negative selection	5502234
158533220	158533243	2	+	27260156	BXPC3	viability	GGGGCAACCACAGACCCGCCAGG	PKP4	ENSG00000144283	0.500351107463485	[80]	[85,163,135,89]	9	hSpCas9	negative selection	5562970
158642578	158642601	2	-	27260156	BXPC3	viability	CTGTAGACTTGCCAAAAACGAGG	PKP4	ENSG00000144283	-0.09569141277188443	[442]	[326,375,390,681]	-2	hSpCas9	negative selection	5562971
158533289	158533312	2	+	27260156	BXPC3	viability	CACTATTCTAGCATCCGTGAAGG	PKP4	ENSG00000144283	-0.24935479953982964	[270]	[178,203,218,374]	-5	hSpCas9	negative selection	5562972
158642477	158642500	2	+	27260156	BXPC3	viability	TCATTCTAGGTGTGTAGGTTAGG	PKP4	ENSG00000144283	-0.3001150922793703	[155]	[125,144,139,115]	-6	hSpCas9	negative selection	5627222
158533220	158533243	2	+	27260156	A673	viability	GGGGCAACCACAGACCCGCCAGG	PKP4	ENSG00000144283	0.2723208208829635	[80]	[155,97,98,121]	6	hSpCas9	negative selection	5684221
158642578	158642601	2	-	27260156	A673	viability	CTGTAGACTTGCCAAAAACGAGG	PKP4	ENSG00000144283	0.0873508463816026	[442]	[597,540,498,629]	2	hSpCas9	negative selection	5684222
158533289	158533312	2	+	27260156	A673	viability	CACTATTCTAGCATCCGTGAAGG	PKP4	ENSG00000144283	-0.09302303567834636	[270]	[309,314,335,255]	-2	hSpCas9	negative selection	5684223
158642477	158642500	2	+	27260156	A673	viability	TCATTCTAGGTGTGTAGGTTAGG	PKP4	ENSG00000144283	-0.13465997041667666	[155]	[231,193,111,149]	-3	hSpCas9	negative selection	5748473
158533220	158533243	2	+	27260156	A375	viability	GGGGCAACCACAGACCCGCCAGG	PKP4	ENSG00000144283	0.7140943344287958	[80]	[138,303,90,111]	9	hSpCas9	negative selection	5805472
158642578	158642601	2	-	27260156	A375	viability	CTGTAGACTTGCCAAAAACGAGG	PKP4	ENSG00000144283	0.2672873095802238	[442]	[785,757,604,387]	4	hSpCas9	negative selection	5805473
158533289	158533312	2	+	27260156	A375	viability	CACTATTCTAGCATCCGTGAAGG	PKP4	ENSG00000144283	0.16226385958098577	[270]	[229,457,303,427]	2	hSpCas9	negative selection	5805474
158642477	158642500	2	+	27260156	A375	viability	TCATTCTAGGTGTGTAGGTTAGG	PKP4	ENSG00000144283	-0.565933659017035	[155]	[96,151,144,103]	-6	hSpCas9	negative selection	5869724
158533220	158533243	2	+	27260156	COLO741	viability	GGGGCAACCACAGACCCGCCAGG	PKP4	ENSG00000144283	0.2567077867789851	[80]	[179,80,114]	5	hSpCas9	negative selection	5926723
158642578	158642601	2	-	27260156	COLO741	viability	CTGTAGACTTGCCAAAAACGAGG	PKP4	ENSG00000144283	-0.012192294936552717	[442]	[649,591,455]	0	hSpCas9	negative selection	5926724
158533289	158533312	2	+	27260156	COLO741	viability	CACTATTCTAGCATCCGTGAAGG	PKP4	ENSG00000144283	-0.07649287788276149	[270]	[272,380,325]	-2	hSpCas9	negative selection	5926725
158642477	158642500	2	+	27260156	COLO741	viability	TCATTCTAGGTGTGTAGGTTAGG	PKP4	ENSG00000144283	-0.6673782343314869	[155]	[175,128,78]	-8	hSpCas9	negative selection	5990975
158533220	158533243	2	+	27260156	CAL120	viability	GGGGCAACCACAGACCCGCCAGG	PKP4	ENSG00000144283	0.7468038763965692	[80]	[112,165,218]	9	hSpCas9	negative selection	6047974
158642578	158642601	2	-	27260156	CAL120	viability	CTGTAGACTTGCCAAAAACGAGG	PKP4	ENSG00000144283	0.6974645825366341	[442]	[1970,450,429]	8	hSpCas9	negative selection	6047975
158533289	158533312	2	+	27260156	CAL120	viability	CACTATTCTAGCATCCGTGAAGG	PKP4	ENSG00000144283	-0.43390509611172423	[270]	[362,216,186]	-6	hSpCas9	negative selection	6047976
158642477	158642500	2	+	27260156	CAL120	viability	TCATTCTAGGTGTGTAGGTTAGG	PKP4	ENSG00000144283	-0.8358093570522382	[155]	[206,79,54]	-8	hSpCas9	negative selection	6112226
158533220	158533243	2	+	27260156	CADOES1	viability	GGGGCAACCACAGACCCGCCAGG	PKP4	ENSG00000144283	0.4399034802671	[80]	[76,146,80,103]	7	hSpCas9	negative selection	6169225
158642578	158642601	2	-	27260156	CADOES1	viability	CTGTAGACTTGCCAAAAACGAGG	PKP4	ENSG00000144283	0.06631034134856102	[442]	[555,344,445,375]	1	hSpCas9	negative selection	6169226
158533289	158533312	2	+	27260156	CADOES1	viability	CACTATTCTAGCATCCGTGAAGG	PKP4	ENSG00000144283	-0.4144710946425584	[270]	[206,168,250,126]	-6	hSpCas9	negative selection	6169227
158642477	158642500	2	+	27260156	CADOES1	viability	TCATTCTAGGTGTGTAGGTTAGG	PKP4	ENSG00000144283	0.017049884329270126	[155]	[125,199,99,161]	0	hSpCas9	negative selection	6233477
158533220	158533243	2	+	27260156	EWS502	viability	GGGGCAACCACAGACCCGCCAGG	PKP4	ENSG00000144283	0.3321317035277196	[80]	[129,131,44,120]	6	hSpCas9	negative selection	6290476
158642578	158642601	2	-	27260156	EWS502	viability	CTGTAGACTTGCCAAAAACGAGG	PKP4	ENSG00000144283	0.1283135314042251	[442]	[500,656,356,528]	2	hSpCas9	negative selection	6290477
158533289	158533312	2	+	27260156	EWS502	viability	CACTATTCTAGCATCCGTGAAGG	PKP4	ENSG00000144283	-0.14003843275601846	[270]	[302,249,280,197]	-3	hSpCas9	negative selection	6290478
158642477	158642500	2	+	27260156	EWS502	viability	TCATTCTAGGTGTGTAGGTTAGG	PKP4	ENSG00000144283	0.09846187999212552	[155]	[232,245,125,84]	1	hSpCas9	negative selection	6354728
158533220	158533243	2	+	27260156	EW8	viability	GGGGCAACCACAGACCCGCCAGG	PKP4	ENSG00000144283	0.4934863256923836	[80]	[57,103,71,134]	8	hSpCas9	negative selection	6411727
158642578	158642601	2	-	27260156	EW8	viability	CTGTAGACTTGCCAAAAACGAGG	PKP4	ENSG00000144283	-0.13205712106453393	[442]	[380,398,267,277]	-3	hSpCas9	negative selection	6411728
158533289	158533312	2	+	27260156	EW8	viability	CACTATTCTAGCATCCGTGAAGG	PKP4	ENSG00000144283	-0.3237216677612601	[270]	[193,143,194,166]	-6	hSpCas9	negative selection	6411729
158642477	158642500	2	+	27260156	EW8	viability	TCATTCTAGGTGTGTAGGTTAGG	PKP4	ENSG00000144283	-0.27229826429597837	[155]	[54,136,116,101]	-5	hSpCas9	negative selection	6475979
158533220	158533243	2	+	27260156	CORL105	viability	GGGGCAACCACAGACCCGCCAGG	PKP4	ENSG00000144283	0.15000091355848477	[80]	[208,59,76,74]	3	hSpCas9	negative selection	6532978
158642578	158642601	2	-	27260156	CORL105	viability	CTGTAGACTTGCCAAAAACGAGG	PKP4	ENSG00000144283	0.041780722819652685	[442]	[464,320,865,536]	0	hSpCas9	negative selection	6532979
158533289	158533312	2	+	27260156	CORL105	viability	CACTATTCTAGCATCCGTGAAGG	PKP4	ENSG00000144283	-0.0026967487084268438	[270]	[266,419,253,311]	0	hSpCas9	negative selection	6532980
158642477	158642500	2	+	27260156	CORL105	viability	TCATTCTAGGTGTGTAGGTTAGG	PKP4	ENSG00000144283	-0.4762032506194438	[155]	[158,96,151,121]	-7	hSpCas9	negative selection	6597230
158533220	158533243	2	+	27260156	HS294T	viability	GGGGCAACCACAGACCCGCCAGG	PKP4	ENSG00000144283	0.5565964194810091	[80]	[54,32,37,59]	7	hSpCas9	negative selection	6654229
158642578	158642601	2	-	27260156	HS294T	viability	CTGTAGACTTGCCAAAAACGAGG	PKP4	ENSG00000144283	0.15129232410466759	[442]	[254,138,104,269]	2	hSpCas9	negative selection	6654230
158533289	158533312	2	+	27260156	HS294T	viability	CACTATTCTAGCATCCGTGAAGG	PKP4	ENSG00000144283	0.10834273315606624	[270]	[59,62,243,86]	1	hSpCas9	negative selection	6654231
158642477	158642500	2	+	27260156	HS294T	viability	TCATTCTAGGTGTGTAGGTTAGG	PKP4	ENSG00000144283	-0.463628261720173	[155]	[47,41,37,46]	-6	hSpCas9	negative selection	6718481
158533220	158533243	2	+	27260156	HCC44	viability	GGGGCAACCACAGACCCGCCAGG	PKP4	ENSG00000144283	1.0518816554819048	[80]	[122,181,129,303]	9	hSpCas9	negative selection	6775480
158642578	158642601	2	-	27260156	HCC44	viability	CTGTAGACTTGCCAAAAACGAGG	PKP4	ENSG00000144283	0.23508022456194771	[442]	[769,557,382,626]	4	hSpCas9	negative selection	6775481
158533289	158533312	2	+	27260156	HCC44	viability	CACTATTCTAGCATCCGTGAAGG	PKP4	ENSG00000144283	-0.11381300737005473	[270]	[200,302,359,269]	-2	hSpCas9	negative selection	6775482
158642477	158642500	2	+	27260156	HCC44	viability	TCATTCTAGGTGTGTAGGTTAGG	PKP4	ENSG00000144283	-0.41642849628011147	[155]	[83,116,254,91]	-6	hSpCas9	negative selection	6839732
158533220	158533243	2	+	27260156	G402	viability	GGGGCAACCACAGACCCGCCAGG	PKP4	ENSG00000144283	0.6678326154987702	[80]	[60,162,233,155]	8	hSpCas9	negative selection	6896731
158642578	158642601	2	-	27260156	G402	viability	CTGTAGACTTGCCAAAAACGAGG	PKP4	ENSG00000144283	0.41052089258067864	[442]	[717,430,809,886]	5	hSpCas9	negative selection	6896732
158533289	158533312	2	+	27260156	G402	viability	CACTATTCTAGCATCCGTGAAGG	PKP4	ENSG00000144283	-0.526561245945334	[270]	[236,171,147,351]	-6	hSpCas9	negative selection	6896733
158642477	158642500	2	+	27260156	G402	viability	TCATTCTAGGTGTGTAGGTTAGG	PKP4	ENSG00000144283	-0.4486099025778345	[155]	[170,87,182,117]	-5	hSpCas9	negative selection	6960983
158533220	158533243	2	+	27260156	L33	viability	GGGGCAACCACAGACCCGCCAGG	PKP4	ENSG00000144283	0.2613396388355671	[80]	[82,45,80,64]	5	hSpCas9	negative selection	7017982
158642578	158642601	2	-	27260156	L33	viability	CTGTAGACTTGCCAAAAACGAGG	PKP4	ENSG00000144283	0.07269170840780995	[442]	[581,132,258,540]	1	hSpCas9	negative selection	7017983
158533289	158533312	2	+	27260156	L33	viability	CACTATTCTAGCATCCGTGAAGG	PKP4	ENSG00000144283	-0.06952697831664345	[270]	[291,90,165,253]	-1	hSpCas9	negative selection	7017984
158642477	158642500	2	+	27260156	L33	viability	TCATTCTAGGTGTGTAGGTTAGG	PKP4	ENSG00000144283	-0.341821811222089	[155]	[89,63,68,136]	-7	hSpCas9	negative selection	7082234
158533220	158533243	2	+	27260156	K562	viability	GGGGCAACCACAGACCCGCCAGG	PKP4	ENSG00000144283	0.0003871609725001335	[80]	[201,37,10,47]	0	hSpCas9	negative selection	7139233
158642578	158642601	2	-	27260156	K562	viability	CTGTAGACTTGCCAAAAACGAGG	PKP4	ENSG00000144283	-0.5433991326652644	[442]	[203,363,216,289]	-6	hSpCas9	negative selection	7139234
158533289	158533312	2	+	27260156	K562	viability	CACTATTCTAGCATCCGTGAAGG	PKP4	ENSG00000144283	0.13299639635332017	[270]	[256,192,368,233]	1	hSpCas9	negative selection	7139235
158642477	158642500	2	+	27260156	K562	viability	TCATTCTAGGTGTGTAGGTTAGG	PKP4	ENSG00000144283	-0.34339541199562706	[155]	[167,94,104,75]	-4	hSpCas9	negative selection	7203485
158533220	158533243	2	+	27260156	HT29	viability	GGGGCAACCACAGACCCGCCAGG	PKP4	ENSG00000144283	0.7215078135801194	[80]	[247,138,122,144]	9	hSpCas9	negative selection	7260484
158642578	158642601	2	-	27260156	HT29	viability	CTGTAGACTTGCCAAAAACGAGG	PKP4	ENSG00000144283	-0.11627732549742816	[442]	[628,497,397,471]	-2	hSpCas9	negative selection	7260485
158533289	158533312	2	+	27260156	HT29	viability	CACTATTCTAGCATCCGTGAAGG	PKP4	ENSG00000144283	0.24508711634318558	[270]	[544,397,377,265]	5	hSpCas9	negative selection	7260486
158642477	158642500	2	+	27260156	HT29	viability	TCATTCTAGGTGTGTAGGTTAGG	PKP4	ENSG00000144283	-0.3706376771302011	[155]	[221,143,67,155]	-6	hSpCas9	negative selection	7324736
158533220	158533243	2	+	27260156	MHHES1	viability	GGGGCAACCACAGACCCGCCAGG	PKP4	ENSG00000144283	0.6208413237473305	[80]	[125,142,245,60]	9	hSpCas9	negative selection	7381735
158642578	158642601	2	-	27260156	MHHES1	viability	CTGTAGACTTGCCAAAAACGAGG	PKP4	ENSG00000144283	0.24610811777054686	[442]	[656,912,440,421]	4	hSpCas9	negative selection	7381736
158533289	158533312	2	+	27260156	MHHES1	viability	CACTATTCTAGCATCCGTGAAGG	PKP4	ENSG00000144283	0.17417913927426287	[270]	[376,377,355,280]	3	hSpCas9	negative selection	7381737
158642477	158642500	2	+	27260156	MHHES1	viability	TCATTCTAGGTGTGTAGGTTAGG	PKP4	ENSG00000144283	-0.18862499419554735	[155]	[197,214,112,108]	-4	hSpCas9	negative selection	7445987
158533220	158533243	2	+	27260156	MEWO	viability	GGGGCAACCACAGACCCGCCAGG	PKP4	ENSG00000144283	0.9212065268378489	[80]	[141,182,104]	9	hSpCas9	negative selection	7502986
158642578	158642601	2	-	27260156	MEWO	viability	CTGTAGACTTGCCAAAAACGAGG	PKP4	ENSG00000144283	-0.0728107858172621	[442]	[454,370,367]	-1	hSpCas9	negative selection	7502987
158533289	158533312	2	+	27260156	MEWO	viability	CACTATTCTAGCATCCGTGAAGG	PKP4	ENSG00000144283	-0.001083704162912369	[270]	[299,257,210]	0	hSpCas9	negative selection	7502988
158642477	158642500	2	+	27260156	MEWO	viability	TCATTCTAGGTGTGTAGGTTAGG	PKP4	ENSG00000144283	-0.2829189415202493	[155]	[110,142,103]	-6	hSpCas9	negative selection	7567238
158533220	158533243	2	+	27260156	LNCAPCLONEFGC	viability	GGGGCAACCACAGACCCGCCAGG	PKP4	ENSG00000144283	0.5797285284568918	[80]	[35,132,119,150]	8	hSpCas9	negative selection	7624237
158642578	158642601	2	-	27260156	LNCAPCLONEFGC	viability	CTGTAGACTTGCCAAAAACGAGG	PKP4	ENSG00000144283	0.34032297829181163	[442]	[486,434,540,578]	5	hSpCas9	negative selection	7624238
158533289	158533312	2	+	27260156	LNCAPCLONEFGC	viability	CACTATTCTAGCATCCGTGAAGG	PKP4	ENSG00000144283	0.007594531353047218	[270]	[191,301,250,239]	0	hSpCas9	negative selection	7624239
158642477	158642500	2	+	27260156	LNCAPCLONEFGC	viability	TCATTCTAGGTGTGTAGGTTAGG	PKP4	ENSG00000144283	-0.12395460840330164	[155]	[126,40,125,229]	-2	hSpCas9	negative selection	7688489
158533220	158533243	2	+	27260156	PANC0327	viability	GGGGCAACCACAGACCCGCCAGG	PKP4	ENSG00000144283	-0.03360879705550612	[80]	[87,36,112,48]	0	hSpCas9	negative selection	7745488
158642578	158642601	2	-	27260156	PANC0327	viability	CTGTAGACTTGCCAAAAACGAGG	PKP4	ENSG00000144283	-0.002375500085502233	[442]	[421,399,449,300]	0	hSpCas9	negative selection	7745489
158533289	158533312	2	+	27260156	PANC0327	viability	CACTATTCTAGCATCCGTGAAGG	PKP4	ENSG00000144283	-0.2682106385949815	[270]	[169,209,310,104]	-4	hSpCas9	negative selection	7745490
158642477	158642500	2	+	27260156	PANC0327	viability	TCATTCTAGGTGTGTAGGTTAGG	PKP4	ENSG00000144283	0.12893596457985534	[155]	[126,37,310,142]	1	hSpCas9	negative selection	7809740
158533220	158533243	2	+	27260156	NCIH2009	viability	GGGGCAACCACAGACCCGCCAGG	PKP4	ENSG00000144283	0.20855928491386067	[80]	[179,120,100]	3	hSpCas9	negative selection	7866739
158642578	158642601	2	-	27260156	NCIH2009	viability	CTGTAGACTTGCCAAAAACGAGG	PKP4	ENSG00000144283	0.28059684734957674	[442]	[750,863,636]	4	hSpCas9	negative selection	7866740
158533289	158533312	2	+	27260156	NCIH2009	viability	CACTATTCTAGCATCCGTGAAGG	PKP4	ENSG00000144283	-0.11985724473057469	[270]	[459,336,269]	-2	hSpCas9	negative selection	7866741
158642477	158642500	2	+	27260156	NCIH2009	viability	TCATTCTAGGTGTGTAGGTTAGG	PKP4	ENSG00000144283	-0.9220557938681	[155]	[134,105,107]	-8	hSpCas9	negative selection	7930991
158533220	158533243	2	+	27260156	NCIH1373	viability	GGGGCAACCACAGACCCGCCAGG	PKP4	ENSG00000144283	0.06965171449819607	[80]	[73,109,50,37]	0	hSpCas9	negative selection	7987990
158642578	158642601	2	-	27260156	NCIH1373	viability	CTGTAGACTTGCCAAAAACGAGG	PKP4	ENSG00000144283	-0.6192828288296228	[442]	[410,149,289,126]	-6	hSpCas9	negative selection	7987991
158533289	158533312	2	+	27260156	NCIH1373	viability	CACTATTCTAGCATCCGTGAAGG	PKP4	ENSG00000144283	-0.24526332692161812	[270]	[484,132,137,84]	-2	hSpCas9	negative selection	7987992
158642477	158642500	2	+	27260156	NCIH1373	viability	TCATTCTAGGTGTGTAGGTTAGG	PKP4	ENSG00000144283	-1.324719281974048	[155]	[100,36,48,26]	-8	hSpCas9	negative selection	8052242
158533220	158533243	2	+	27260156	PATU8902	viability	GGGGCAACCACAGACCCGCCAGG	PKP4	ENSG00000144283	0.6942488097846551	[80]	[252,217,147,108]	7	hSpCas9	negative selection	8109241
158642578	158642601	2	-	27260156	PATU8902	viability	CTGTAGACTTGCCAAAAACGAGG	PKP4	ENSG00000144283	-0.02882373799005429	[442]	[345,308,566,1285]	0	hSpCas9	negative selection	8109242
158533289	158533312	2	+	27260156	PATU8902	viability	CACTATTCTAGCATCCGTGAAGG	PKP4	ENSG00000144283	0.10714870786773534	[270]	[203,353,498,562]	1	hSpCas9	negative selection	8109243
158642477	158642500	2	+	27260156	PATU8902	viability	TCATTCTAGGTGTGTAGGTTAGG	PKP4	ENSG00000144283	-0.2025320090611309	[155]	[163,312,134,151]	-2	hSpCas9	negative selection	8173493
158533220	158533243	2	+	27260156	PANC1	viability	GGGGCAACCACAGACCCGCCAGG	PKP4	ENSG00000144283	0.018115644460630964	[80]	[106,55,91,28]	0	hSpCas9	negative selection	8230492
158642578	158642601	2	-	27260156	PANC1	viability	CTGTAGACTTGCCAAAAACGAGG	PKP4	ENSG00000144283	0.313456057778054	[442]	[507,434,493,442]	5	hSpCas9	negative selection	8230493
158533289	158533312	2	+	27260156	PANC1	viability	CACTATTCTAGCATCCGTGAAGG	PKP4	ENSG00000144283	-0.5728543594967165	[270]	[178,244,117,106]	-7	hSpCas9	negative selection	8230494
158642477	158642500	2	+	27260156	PANC1	viability	TCATTCTAGGTGTGTAGGTTAGG	PKP4	ENSG00000144283	-0.05643787580661708	[155]	[124,229,92,91]	-1	hSpCas9	negative selection	8294744
158533220	158533243	2	+	27260156	PANC0813	viability	GGGGCAACCACAGACCCGCCAGG	PKP4	ENSG00000144283	0.5225222449714564	[80]	[169,152,49,173]	8	hSpCas9	negative selection	8351743
158642578	158642601	2	-	27260156	PANC0813	viability	CTGTAGACTTGCCAAAAACGAGG	PKP4	ENSG00000144283	0.10639887554569186	[442]	[582,590,615,457]	1	hSpCas9	negative selection	8351744
158533289	158533312	2	+	27260156	PANC0813	viability	CACTATTCTAGCATCCGTGAAGG	PKP4	ENSG00000144283	0.11836150088209063	[270]	[326,281,385,382]	2	hSpCas9	negative selection	8351745
158642477	158642500	2	+	27260156	PANC0813	viability	TCATTCTAGGTGTGTAGGTTAGG	PKP4	ENSG00000144283	-0.002509607607186215	[155]	[143,256,133,191]	0	hSpCas9	negative selection	8415995
158533220	158533243	2	+	27260156	RDES	viability	GGGGCAACCACAGACCCGCCAGG	PKP4	ENSG00000144283	0.16401005237078703	[80]	[88,123,69,135]	2	hSpCas9	negative selection	8472994
158642578	158642601	2	-	27260156	RDES	viability	CTGTAGACTTGCCAAAAACGAGG	PKP4	ENSG00000144283	0.03947635785447256	[442]	[472,376,571,711]	0	hSpCas9	negative selection	8472995
158533289	158533312	2	+	27260156	RDES	viability	CACTATTCTAGCATCCGTGAAGG	PKP4	ENSG00000144283	-0.13930589788352865	[270]	[289,207,338,294]	-2	hSpCas9	negative selection	8472996
158642477	158642500	2	+	27260156	RDES	viability	TCATTCTAGGTGTGTAGGTTAGG	PKP4	ENSG00000144283	-0.18677551120650526	[155]	[134,162,177,153]	-3	hSpCas9	negative selection	8537246
158533220	158533243	2	+	27260156	PC3	viability	GGGGCAACCACAGACCCGCCAGG	PKP4	ENSG00000144283	0.45652616990408035	[80]	[54,176,194,57]	8	hSpCas9	negative selection	8594245
158642578	158642601	2	-	27260156	PC3	viability	CTGTAGACTTGCCAAAAACGAGG	PKP4	ENSG00000144283	0.164617837978336	[442]	[235,529,692,678]	3	hSpCas9	negative selection	8594246
158533289	158533312	2	+	27260156	PC3	viability	CACTATTCTAGCATCCGTGAAGG	PKP4	ENSG00000144283	0.05950352451481855	[270]	[166,316,487,254]	1	hSpCas9	negative selection	8594247
158642477	158642500	2	+	27260156	PC3	viability	TCATTCTAGGTGTGTAGGTTAGG	PKP4	ENSG00000144283	-0.5982788018328393	[155]	[96,79,36,162]	-8	hSpCas9	negative selection	8658497
158533220	158533243	2	+	27260156	PATU8988T	viability	GGGGCAACCACAGACCCGCCAGG	PKP4	ENSG00000144283	0.3339847386675707	[80]	[92,105,90,105]	6	hSpCas9	negative selection	8715496
158642578	158642601	2	-	27260156	PATU8988T	viability	CTGTAGACTTGCCAAAAACGAGG	PKP4	ENSG00000144283	0.15299295737146212	[442]	[291,673,501,451]	2	hSpCas9	negative selection	8715497
158533289	158533312	2	+	27260156	PATU8988T	viability	CACTATTCTAGCATCCGTGAAGG	PKP4	ENSG00000144283	0.24614750401166152	[270]	[241,478,121,426]	4	hSpCas9	negative selection	8715498
158642477	158642500	2	+	27260156	PATU8988T	viability	TCATTCTAGGTGTGTAGGTTAGG	PKP4	ENSG00000144283	-0.8815691905140688	[155]	[119,53,86,61]	-8	hSpCas9	negative selection	8779748
158533220	158533243	2	+	27260156	T47D	viability	GGGGCAACCACAGACCCGCCAGG	PKP4	ENSG00000144283	0.35152766374035593	[80]	[98,108,131,142]	7	hSpCas9	negative selection	8836747
158642578	158642601	2	-	27260156	T47D	viability	CTGTAGACTTGCCAAAAACGAGG	PKP4	ENSG00000144283	0.2468988914361444	[442]	[632,536,452,842]	5	hSpCas9	negative selection	8836748
158533289	158533312	2	+	27260156	T47D	viability	CACTATTCTAGCATCCGTGAAGG	PKP4	ENSG00000144283	-0.24399793236648415	[270]	[239,249,287,289]	-5	hSpCas9	negative selection	8836749
158642477	158642500	2	+	27260156	T47D	viability	TCATTCTAGGTGTGTAGGTTAGG	PKP4	ENSG00000144283	-0.15898186750826193	[155]	[154,143,214,136]	-4	hSpCas9	negative selection	8900999
158533220	158533243	2	+	27260156	SU8686	viability	GGGGCAACCACAGACCCGCCAGG	PKP4	ENSG00000144283	0.7541164453159337	[80]	[186,112,62,179]	9	hSpCas9	negative selection	8957998
158642578	158642601	2	-	27260156	SU8686	viability	CTGTAGACTTGCCAAAAACGAGG	PKP4	ENSG00000144283	-0.38661931751421835	[442]	[210,314,338,523]	-6	hSpCas9	negative selection	8957999
158533289	158533312	2	+	27260156	SU8686	viability	CACTATTCTAGCATCCGTGAAGG	PKP4	ENSG00000144283	0.5381681405629619	[270]	[357,279,360,611]	8	hSpCas9	negative selection	8958000
158642477	158642500	2	+	27260156	SU8686	viability	TCATTCTAGGTGTGTAGGTTAGG	PKP4	ENSG00000144283	-0.5938716672221038	[155]	[84,126,59,140]	-7	hSpCas9	negative selection	9022250
158533220	158533243	2	+	27260156	SKES1	viability	GGGGCAACCACAGACCCGCCAGG	PKP4	ENSG00000144283	0.24080799344049586	[80]	[149,109,76,57]	5	hSpCas9	negative selection	9079249
158642578	158642601	2	-	27260156	SKES1	viability	CTGTAGACTTGCCAAAAACGAGG	PKP4	ENSG00000144283	-0.476610026561979	[442]	[250,333,354,318]	-8	hSpCas9	negative selection	9079250
158533289	158533312	2	+	27260156	SKES1	viability	CACTATTCTAGCATCCGTGAAGG	PKP4	ENSG00000144283	-0.28884461861961974	[270]	[291,296,171,149]	-6	hSpCas9	negative selection	9079251
158642477	158642500	2	+	27260156	SKES1	viability	TCATTCTAGGTGTGTAGGTTAGG	PKP4	ENSG00000144283	-0.3519417073189042	[155]	[120,132,103,128]	-7	hSpCas9	negative selection	9143501
158533220	158533243	2	+	27260156	TOV112D	viability	GGGGCAACCACAGACCCGCCAGG	PKP4	ENSG00000144283	0.374357184351358	[80]	[96,50,136,120]	7	hSpCas9	negative selection	9200500
158642578	158642601	2	-	27260156	TOV112D	viability	CTGTAGACTTGCCAAAAACGAGG	PKP4	ENSG00000144283	-0.3330648207004989	[442]	[338,494,316,292]	-6	hSpCas9	negative selection	9200501
158533289	158533312	2	+	27260156	TOV112D	viability	CACTATTCTAGCATCCGTGAAGG	PKP4	ENSG00000144283	-0.03320876708836151	[270]	[371,289,270,145]	0	hSpCas9	negative selection	9200502
158642477	158642500	2	+	27260156	TOV112D	viability	TCATTCTAGGTGTGTAGGTTAGG	PKP4	ENSG00000144283	-0.34934545994222677	[155]	[184,132,87,92]	-6	hSpCas9	negative selection	9264752
158533220	158533243	2	+	27260156	TC71	viability	GGGGCAACCACAGACCCGCCAGG	PKP4	ENSG00000144283	0.45042767168364595	[80]	[139,95,129,106]	9	hSpCas9	negative selection	9321751
158642578	158642601	2	-	27260156	TC71	viability	CTGTAGACTTGCCAAAAACGAGG	PKP4	ENSG00000144283	-0.016481579781127617	[442]	[471,398,471,538]	0	hSpCas9	negative selection	9321752
158533289	158533312	2	+	27260156	TC71	viability	CACTATTCTAGCATCCGTGAAGG	PKP4	ENSG00000144283	-0.17087645070452173	[270]	[165,243,300,325]	-4	hSpCas9	negative selection	9321753
158642477	158642500	2	+	27260156	TC71	viability	TCATTCTAGGTGTGTAGGTTAGG	PKP4	ENSG00000144283	-0.1390932375659224	[155]	[125,172,164,142]	-4	hSpCas9	negative selection	9386003
158533220	158533243	2	+	27260156	TC32	viability	GGGGCAACCACAGACCCGCCAGG	PKP4	ENSG00000144283	0.4750103119761211	[80]	[118,36,213,89]	7	hSpCas9	negative selection	9443002
158642578	158642601	2	-	27260156	TC32	viability	CTGTAGACTTGCCAAAAACGAGG	PKP4	ENSG00000144283	-0.15717551670280955	[442]	[328,288,531,386]	-3	hSpCas9	negative selection	9443003
158533289	158533312	2	+	27260156	TC32	viability	CACTATTCTAGCATCCGTGAAGG	PKP4	ENSG00000144283	-0.09271000077292646	[270]	[250,132,371,247]	-2	hSpCas9	negative selection	9443004
158642477	158642500	2	+	27260156	TC32	viability	TCATTCTAGGTGTGTAGGTTAGG	PKP4	ENSG00000144283	-0.7382364177871801	[155]	[123,0,190,76]	-9	hSpCas9	negative selection	9507254
158533199	158533222	2	+	27869803	HPAFII	viability after 27 days	GCAGGCCTCATTGGTGGAGGAGG	PKP4	ENSG00000144283	1.5466282244309248	[198]	[255,346,NaN]	9	hSpCas9	negative selection	9571994
158577362	158577385	2	+	27869803	HPAFII	viability after 27 days	CACCAAGCATCGCCAGCACCAGG	PKP4	ENSG00000144283	0.00796561768797066	[329]	[198,153,NaN]	0	hSpCas9	negative selection	9571995
158624956	158624979	2	+	27869803	HPAFII	viability after 27 days	ACAGGCGTGTCTCCTTCAAGGGG	PKP4	ENSG00000144283	0.817785350428665	[262]	[204,275,NaN]	6	hSpCas9	negative selection	9571996
158631923	158631946	2	+	27869803	HPAFII	viability after 27 days	TTGTATCGCACAGGTTCAGGTGG	PKP4	ENSG00000144283	0.6346224119917896	[185]	[75,214,NaN]	5	hSpCas9	negative selection	9571997
158533199	158533222	2	+	27869803	HPAFII	viability after 15 days	GCAGGCCTCATTGGTGGAGGAGG	PKP4	ENSG00000144283	1.1921218926312376	[198]	[537,457,NaN]	9	hSpCas9	negative selection	9654443
158577362	158577385	2	+	27869803	HPAFII	viability after 15 days	CACCAAGCATCGCCAGCACCAGG	PKP4	ENSG00000144283	0.10560349608219827	[329]	[507,302,NaN]	1	hSpCas9	negative selection	9654444
158624956	158624979	2	+	27869803	HPAFII	viability after 15 days	ACAGGCGTGTCTCCTTCAAGGGG	PKP4	ENSG00000144283	0.3843833966012592	[262]	[355,376,NaN]	4	hSpCas9	negative selection	9654445
158631923	158631946	2	+	27869803	HPAFII	viability after 15 days	TTGTATCGCACAGGTTCAGGTGG	PKP4	ENSG00000144283	0.5235401274918108	[185]	[303,276,NaN]	6	hSpCas9	negative selection	9654446
158533199	158533222	2	+	27869803	ASPC1	viability after 36 days	GCAGGCCTCATTGGTGGAGGAGG	PKP4	ENSG00000144283	0.4522789427470625	[618]	[354,166,352]	4	hSpCas9	negative selection	9736892
158577362	158577385	2	+	27869803	ASPC1	viability after 36 days	CACCAAGCATCGCCAGCACCAGG	PKP4	ENSG00000144283	0.6803372264214739	[1036]	[567,945,291]	6	hSpCas9	negative selection	9736893
158624956	158624979	2	+	27869803	ASPC1	viability after 36 days	ACAGGCGTGTCTCCTTCAAGGGG	PKP4	ENSG00000144283	0.09556987897698485	[639]	[205,122,350]	0	hSpCas9	negative selection	9736894
158631923	158631946	2	+	27869803	ASPC1	viability after 36 days	TTGTATCGCACAGGTTCAGGTGG	PKP4	ENSG00000144283	0.7605667643311385	[431]	[193,335,231]	7	hSpCas9	negative selection	9736895
158533199	158533222	2	+	27869803	PATU8988S	viability after 35 days	GCAGGCCTCATTGGTGGAGGAGG	PKP4	ENSG00000144283	0.4439347991795654	[551]	[267,336,NaN]	5	hSpCas9	negative selection	9819341
158577362	158577385	2	+	27869803	PATU8988S	viability after 35 days	CACCAAGCATCGCCAGCACCAGG	PKP4	ENSG00000144283	0.814476073830847	[890]	[672,588,NaN]	8	hSpCas9	negative selection	9819342
158624956	158624979	2	+	27869803	PATU8988S	viability after 35 days	ACAGGCGTGTCTCCTTCAAGGGG	PKP4	ENSG00000144283	0.1314133911278658	[624]	[154,396,NaN]	1	hSpCas9	negative selection	9819343
158631923	158631946	2	+	27869803	PATU8988S	viability after 35 days	TTGTATCGCACAGGTTCAGGTGG	PKP4	ENSG00000144283	0.0742411191917991	[367]	[172,138,NaN]	0	hSpCas9	negative selection	9819344
158533199	158533222	2	+	27869803	PATU8988S	viability after 31 days	GCAGGCCTCATTGGTGGAGGAGG	PKP4	ENSG00000144283	0.4292516568792666	[551]	[203,413,NaN]	5	hSpCas9	negative selection	9901790
158577362	158577385	2	+	27869803	PATU8988S	viability after 31 days	CACCAAGCATCGCCAGCACCAGG	PKP4	ENSG00000144283	0.3125620428214302	[890]	[376,522,NaN]	4	hSpCas9	negative selection	9901791
158624956	158624979	2	+	27869803	PATU8988S	viability after 31 days	ACAGGCGTGTCTCCTTCAAGGGG	PKP4	ENSG00000144283	0.09849473195502376	[624]	[184,370,NaN]	1	hSpCas9	negative selection	9901792
158631923	158631946	2	+	27869803	PATU8988S	viability after 31 days	TTGTATCGCACAGGTTCAGGTGG	PKP4	ENSG00000144283	-0.10339126026933276	[367]	[85,200,NaN]	-1	hSpCas9	negative selection	9901793
158533199	158533222	2	+	27869803	HPAFII	viability after 35 days	GCAGGCCTCATTGGTGGAGGAGG	PKP4	ENSG00000144283	1.0121194948802512	[198]	[102,315,NaN]	6	hSpCas9	negative selection	9984239
158577362	158577385	2	+	27869803	HPAFII	viability after 35 days	CACCAAGCATCGCCAGCACCAGG	PKP4	ENSG00000144283	-0.2661954014717968	[329]	[81,202,NaN]	-2	hSpCas9	negative selection	9984240
158624956	158624979	2	+	27869803	HPAFII	viability after 35 days	ACAGGCGTGTCTCCTTCAAGGGG	PKP4	ENSG00000144283	1.0583109063986436	[262]	[225,334,NaN]	7	hSpCas9	negative selection	9984241
158631923	158631946	2	+	27869803	HPAFII	viability after 35 days	TTGTATCGCACAGGTTCAGGTGG	PKP4	ENSG00000144283	0.927732739461111	[185]	[69,301,NaN]	6	hSpCas9	negative selection	9984242
158533199	158533222	2	+	27869803	HPAFII	viability after 31 days	GCAGGCCTCATTGGTGGAGGAGG	PKP4	ENSG00000144283	1.4008984774706925	[198]	[158,442,NaN]	8	hSpCas9	negative selection	10066688
158577362	158577385	2	+	27869803	HPAFII	viability after 31 days	CACCAAGCATCGCCAGCACCAGG	PKP4	ENSG00000144283	-0.18043459984977292	[329]	[105,225,NaN]	-1	hSpCas9	negative selection	10066689
158624956	158624979	2	+	27869803	HPAFII	viability after 31 days	ACAGGCGTGTCTCCTTCAAGGGG	PKP4	ENSG00000144283	0.9164666692358214	[262]	[235,324,NaN]	7	hSpCas9	negative selection	10066690
158631923	158631946	2	+	27869803	HPAFII	viability after 31 days	TTGTATCGCACAGGTTCAGGTGG	PKP4	ENSG00000144283	0.8841042539503388	[185]	[50,346,NaN]	6	hSpCas9	negative selection	10066691
158533235	158533258	2	-	28162770	P31FUJ	viability	CAGTGGAGGCAGCTTCCTGGCGG	PKP4	ENSG00000144283	0.18479553518302927	[562]	[751]	2	hSpCas9	negative selection	10212031
158533188	158533211	2	-	28162770	P31FUJ	viability	AATGAGGCCTGCTCAGGAGCTGG	PKP4	ENSG00000144283	0.5690706526268101	[338]	[590]	6	hSpCas9	negative selection	10212032
158625197	158625220	2	-	28162770	P31FUJ	viability	TGGGGACCCCACTCTGGCGGTGG	PKP4	ENSG00000144283	0.08453862097733186	[251]	[313]	0	hSpCas9	negative selection	10212033
158625210	158625233	2	+	28162770	P31FUJ	viability	GGGGTCCCCACTGACCCTGACGG	PKP4	ENSG00000144283	-0.23280220441437854	[228]	[228]	-2	hSpCas9	negative selection	10212034
158631799	158631822	2	-	28162770	P31FUJ	viability	CGGGAGACACGGCAGAACGAAGG	PKP4	ENSG00000144283	1.2492603887224867	[91]	[256]	9	hSpCas9	negative selection	10212035
158631869	158631892	2	+	28162770	P31FUJ	viability	GTGTACCGCAGCCCAAACCATGG	PKP4	ENSG00000144283	-0.16303192611020445	[443]	[465]	-1	hSpCas9	negative selection	10212036
158533235	158533258	2	-	28162770	TF1	viability	CAGTGGAGGCAGCTTCCTGGCGG	PKP4	ENSG00000144283	NaN	[NaN]	[242]	1	hSpCas9	negative selection	10381397
158533188	158533211	2	-	28162770	TF1	viability	AATGAGGCCTGCTCAGGAGCTGG	PKP4	ENSG00000144283	NaN	[NaN]	[173]	1	hSpCas9	negative selection	10381398
158625197	158625220	2	-	28162770	TF1	viability	TGGGGACCCCACTCTGGCGGTGG	PKP4	ENSG00000144283	NaN	[NaN]	[97]	1	hSpCas9	negative selection	10381399
158625210	158625233	2	+	28162770	TF1	viability	GGGGTCCCCACTGACCCTGACGG	PKP4	ENSG00000144283	NaN	[NaN]	[71]	1	hSpCas9	negative selection	10381400
158631799	158631822	2	-	28162770	TF1	viability	CGGGAGACACGGCAGAACGAAGG	PKP4	ENSG00000144283	NaN	[NaN]	[170]	1	hSpCas9	negative selection	10381401
158631869	158631892	2	+	28162770	TF1	viability	GTGTACCGCAGCCCAAACCATGG	PKP4	ENSG00000144283	NaN	[NaN]	[332]	1	hSpCas9	negative selection	10381402
158533235	158533258	2	-	28162770	SKM1	viability	CAGTGGAGGCAGCTTCCTGGCGG	PKP4	ENSG00000144283	0.37690237039207264	[114]	[263]	3	hSpCas9	negative selection	10550763
158533188	158533211	2	-	28162770	SKM1	viability	AATGAGGCCTGCTCAGGAGCTGG	PKP4	ENSG00000144283	0.6429610265885208	[70]	[195]	6	hSpCas9	negative selection	10550764
158625197	158625220	2	-	28162770	SKM1	viability	TGGGGACCCCACTCTGGCGGTGG	PKP4	ENSG00000144283	0.19875686214479182	[68]	[139]	2	hSpCas9	negative selection	10550765
158625210	158625233	2	+	28162770	SKM1	viability	GGGGTCCCCACTGACCCTGACGG	PKP4	ENSG00000144283	0.8560702070906321	[54]	[175]	7	hSpCas9	negative selection	10550766
158631799	158631822	2	-	28162770	SKM1	viability	CGGGAGACACGGCAGAACGAAGG	PKP4	ENSG00000144283	1.0308940079457838	[48]	[176]	8	hSpCas9	negative selection	10550767
158631869	158631892	2	+	28162770	SKM1	viability	GTGTACCGCAGCCCAAACCATGG	PKP4	ENSG00000144283	-0.5306619229680659	[142]	[174]	-4	hSpCas9	negative selection	10550768
158533235	158533258	2	-	28162770	SKM1	viability	CAGTGGAGGCAGCTTCCTGGCGG	PKP4	ENSG00000144283	0.37690237039207264	[114]	[263]	3	hSpCas9	negative selection	10720129
158533188	158533211	2	-	28162770	SKM1	viability	AATGAGGCCTGCTCAGGAGCTGG	PKP4	ENSG00000144283	0.6429610265885208	[70]	[195]	6	hSpCas9	negative selection	10720130
158625197	158625220	2	-	28162770	SKM1	viability	TGGGGACCCCACTCTGGCGGTGG	PKP4	ENSG00000144283	0.19875686214479182	[68]	[139]	2	hSpCas9	negative selection	10720131
158625210	158625233	2	+	28162770	SKM1	viability	GGGGTCCCCACTGACCCTGACGG	PKP4	ENSG00000144283	0.8560702070906321	[54]	[175]	7	hSpCas9	negative selection	10720132
158631799	158631822	2	-	28162770	SKM1	viability	CGGGAGACACGGCAGAACGAAGG	PKP4	ENSG00000144283	1.0308940079457838	[48]	[176]	8	hSpCas9	negative selection	10720133
158631869	158631892	2	+	28162770	SKM1	viability	GTGTACCGCAGCCCAAACCATGG	PKP4	ENSG00000144283	-0.5306619229680659	[142]	[174]	-4	hSpCas9	negative selection	10720134
158533235	158533258	2	-	28162770	PL21	viability	CAGTGGAGGCAGCTTCCTGGCGG	PKP4	ENSG00000144283	0.21924843743702493	[449]	[227]	2	hSpCas9	negative selection	10889495
158533188	158533211	2	-	28162770	PL21	viability	AATGAGGCCTGCTCAGGAGCTGG	PKP4	ENSG00000144283	0.7306543311880997	[197]	[142]	6	hSpCas9	negative selection	10889496
158625197	158625220	2	-	28162770	PL21	viability	TGGGGACCCCACTCTGGCGGTGG	PKP4	ENSG00000144283	-2.0771983293739718	[222]	[22]	-8	hSpCas9	negative selection	10889497
158625210	158625233	2	+	28162770	PL21	viability	GGGGTCCCCACTGACCCTGACGG	PKP4	ENSG00000144283	1.1593333981014344	[250]	[243]	8	hSpCas9	negative selection	10889498
158631799	158631822	2	-	28162770	PL21	viability	CGGGAGACACGGCAGAACGAAGG	PKP4	ENSG00000144283	-0.3568085100622395	[152]	[51]	-3	hSpCas9	negative selection	10889499
158631869	158631892	2	+	28162770	PL21	viability	GTGTACCGCAGCCCAAACCATGG	PKP4	ENSG00000144283	0.47714696287571834	[410]	[248]	4	hSpCas9	negative selection	10889500
158533235	158533258	2	-	28162770	P31FUJ	viability	CAGTGGAGGCAGCTTCCTGGCGG	PKP4	ENSG00000144283	0.18479553518302927	[562]	[751]	2	hSpCas9	negative selection	11058861
158533188	158533211	2	-	28162770	P31FUJ	viability	AATGAGGCCTGCTCAGGAGCTGG	PKP4	ENSG00000144283	0.5690706526268101	[338]	[590]	6	hSpCas9	negative selection	11058862
158625197	158625220	2	-	28162770	P31FUJ	viability	TGGGGACCCCACTCTGGCGGTGG	PKP4	ENSG00000144283	0.08453862097733186	[251]	[313]	0	hSpCas9	negative selection	11058863
158625210	158625233	2	+	28162770	P31FUJ	viability	GGGGTCCCCACTGACCCTGACGG	PKP4	ENSG00000144283	-0.23280220441437854	[228]	[228]	-2	hSpCas9	negative selection	11058864
158631799	158631822	2	-	28162770	P31FUJ	viability	CGGGAGACACGGCAGAACGAAGG	PKP4	ENSG00000144283	1.2492603887224867	[91]	[256]	9	hSpCas9	negative selection	11058865
158631869	158631892	2	+	28162770	P31FUJ	viability	GTGTACCGCAGCCCAAACCATGG	PKP4	ENSG00000144283	-0.16303192611020445	[443]	[465]	-1	hSpCas9	negative selection	11058866
158533235	158533258	2	-	28162770	OCIAML5	viability	CAGTGGAGGCAGCTTCCTGGCGG	PKP4	ENSG00000144283	-0.052577663559148835	[288]	[502]	0	hSpCas9	negative selection	11228227
158533188	158533211	2	-	28162770	OCIAML5	viability	AATGAGGCCTGCTCAGGAGCTGG	PKP4	ENSG00000144283	0.48353646092044195	[104]	[264]	4	hSpCas9	negative selection	11228228
158625197	158625220	2	-	28162770	OCIAML5	viability	TGGGGACCCCACTCTGGCGGTGG	PKP4	ENSG00000144283	0.5294962238637587	[108]	[283]	4	hSpCas9	negative selection	11228229
158625210	158625233	2	+	28162770	OCIAML5	viability	GGGGTCCCCACTGACCCTGACGG	PKP4	ENSG00000144283	-0.20596377532893695	[153]	[240]	-1	hSpCas9	negative selection	11228230
158631799	158631822	2	-	28162770	OCIAML5	viability	CGGGAGACACGGCAGAACGAAGG	PKP4	ENSG00000144283	-0.018424957286117122	[100]	[179]	0	hSpCas9	negative selection	11228231
158631869	158631892	2	+	28162770	OCIAML5	viability	GTGTACCGCAGCCCAAACCATGG	PKP4	ENSG00000144283	-0.42302221359127395	[204]	[275]	-3	hSpCas9	negative selection	11228232
158533235	158533258	2	-	28162770	EOL1	viability	CAGTGGAGGCAGCTTCCTGGCGG	PKP4	ENSG00000144283	0.510605297043228	[877]	[658]	4	hSpCas9	negative selection	11397593
158533188	158533211	2	-	28162770	EOL1	viability	AATGAGGCCTGCTCAGGAGCTGG	PKP4	ENSG00000144283	1.0149117992231989	[262]	[279]	8	hSpCas9	negative selection	11397594
158625197	158625220	2	-	28162770	EOL1	viability	TGGGGACCCCACTCTGGCGGTGG	PKP4	ENSG00000144283	-0.3117502517911317	[416]	[176]	-2	hSpCas9	negative selection	11397595
158625210	158625233	2	+	28162770	EOL1	viability	GGGGTCCCCACTGACCCTGACGG	PKP4	ENSG00000144283	0.5398839213352097	[422]	[323]	5	hSpCas9	negative selection	11397596
158631799	158631822	2	-	28162770	EOL1	viability	CGGGAGACACGGCAGAACGAAGG	PKP4	ENSG00000144283	0.0076035112980930575	[269]	[142]	0	hSpCas9	negative selection	11397597
158631869	158631892	2	+	28162770	EOL1	viability	GTGTACCGCAGCCCAAACCATGG	PKP4	ENSG00000144283	0.13949917838271508	[721]	[418]	1	hSpCas9	negative selection	11397598
158533235	158533258	2	-	28162770	MOLM13	viability	CAGTGGAGGCAGCTTCCTGGCGG	PKP4	ENSG00000144283	0.38733681136123743	[754]	[713]	3	hSpCas9	negative selection	11566959
158533188	158533211	2	-	28162770	MOLM13	viability	AATGAGGCCTGCTCAGGAGCTGG	PKP4	ENSG00000144283	0.8031996883526885	[278]	[351]	6	hSpCas9	negative selection	11566960
158625197	158625220	2	-	28162770	MOLM13	viability	TGGGGACCCCACTCTGGCGGTGG	PKP4	ENSG00000144283	0.8139972889270676	[283]	[360]	6	hSpCas9	negative selection	11566961
158625210	158625233	2	+	28162770	MOLM13	viability	GGGGTCCCCACTGACCCTGACGG	PKP4	ENSG00000144283	1.548290888138778	[252]	[534]	9	hSpCas9	negative selection	11566962
158631799	158631822	2	-	28162770	MOLM13	viability	CGGGAGACACGGCAGAACGAAGG	PKP4	ENSG00000144283	0.7989278948766545	[220]	[277]	6	hSpCas9	negative selection	11566963
158631869	158631892	2	+	28162770	MOLM13	viability	GTGTACCGCAGCCCAAACCATGG	PKP4	ENSG00000144283	0.7207028957327247	[542]	[646]	5	hSpCas9	negative selection	11566964
158533235	158533258	2	-	28162770	HEL	viability	CAGTGGAGGCAGCTTCCTGGCGG	PKP4	ENSG00000144283	0.6059468006307211	[555]	[541]	5	hSpCas9	negative selection	11736325
158533188	158533211	2	-	28162770	HEL	viability	AATGAGGCCTGCTCAGGAGCTGG	PKP4	ENSG00000144283	0.12234833257528432	[283]	[197]	1	hSpCas9	negative selection	11736326
158625197	158625220	2	-	28162770	HEL	viability	TGGGGACCCCACTCTGGCGGTGG	PKP4	ENSG00000144283	0.028987907854575834	[328]	[214]	0	hSpCas9	negative selection	11736327
158625210	158625233	2	+	28162770	HEL	viability	GGGGTCCCCACTGACCCTGACGG	PKP4	ENSG00000144283	0.5956048564092621	[279]	[270]	5	hSpCas9	negative selection	11736328
158631799	158631822	2	-	28162770	HEL	viability	CGGGAGACACGGCAGAACGAAGG	PKP4	ENSG00000144283	0.39439186949410193	[214]	[180]	3	hSpCas9	negative selection	11736329
158631869	158631892	2	+	28162770	HEL	viability	GTGTACCGCAGCCCAAACCATGG	PKP4	ENSG00000144283	1.1644364392634965	[504]	[724]	8	hSpCas9	negative selection	11736330
158533235	158533258	2	-	28162770	MV411	viability	CAGTGGAGGCAGCTTCCTGGCGG	PKP4	ENSG00000144283	0.2893590002158799	[406]	[418]	2	hSpCas9	negative selection	11905691
158533188	158533211	2	-	28162770	MV411	viability	AATGAGGCCTGCTCAGGAGCTGG	PKP4	ENSG00000144283	0.040437179863309525	[201]	[174]	0	hSpCas9	negative selection	11905692
158625197	158625220	2	-	28162770	MV411	viability	TGGGGACCCCACTCTGGCGGTGG	PKP4	ENSG00000144283	-0.37800401929345107	[252]	[163]	-3	hSpCas9	negative selection	11905693
158625210	158625233	2	+	28162770	MV411	viability	GGGGTCCCCACTGACCCTGACGG	PKP4	ENSG00000144283	0.712872902765551	[217]	[300]	6	hSpCas9	negative selection	11905694
158631799	158631822	2	-	28162770	MV411	viability	CGGGAGACACGGCAGAACGAAGG	PKP4	ENSG00000144283	0.14123814695085024	[154]	[143]	1	hSpCas9	negative selection	11905695
158631869	158631892	2	+	28162770	MV411	viability	GTGTACCGCAGCCCAAACCATGG	PKP4	ENSG00000144283	-0.2506816899906237	[410]	[290]	-2	hSpCas9	negative selection	11905696
158533235	158533258	2	-	28162770	MONOMAC1	viability	CAGTGGAGGCAGCTTCCTGGCGG	PKP4	ENSG00000144283	0.06452617155757201	[326]	[391]	0	hSpCas9	negative selection	12075057
158533188	158533211	2	-	28162770	MONOMAC1	viability	AATGAGGCCTGCTCAGGAGCTGG	PKP4	ENSG00000144283	0.1721969626061653	[119]	[154]	1	hSpCas9	negative selection	12075058
158625197	158625220	2	-	28162770	MONOMAC1	viability	TGGGGACCCCACTCTGGCGGTGG	PKP4	ENSG00000144283	-0.0030949644987058322	[138]	[158]	0	hSpCas9	negative selection	12075059
158625210	158625233	2	+	28162770	MONOMAC1	viability	GGGGTCCCCACTGACCCTGACGG	PKP4	ENSG00000144283	0.6988547495997077	[157]	[293]	6	hSpCas9	negative selection	12075060
158631799	158631822	2	-	28162770	MONOMAC1	viability	CGGGAGACACGGCAGAACGAAGG	PKP4	ENSG00000144283	0.419048171157383	[106]	[163]	4	hSpCas9	negative selection	12075061
158631869	158631892	2	+	28162770	MONOMAC1	viability	GTGTACCGCAGCCCAAACCATGG	PKP4	ENSG00000144283	0.08549373440003738	[244]	[297]	0	hSpCas9	negative selection	12075062
158533235	158533258	2	-	28162770	OCIAML2	viability	CAGTGGAGGCAGCTTCCTGGCGG	PKP4	ENSG00000144283	0.47422862056537785	[79]	[615]	4	hSpCas9	negative selection	12244423
158533188	158533211	2	-	28162770	OCIAML2	viability	AATGAGGCCTGCTCAGGAGCTGG	PKP4	ENSG00000144283	0.24818842221378576	[35]	[236]	2	hSpCas9	negative selection	12244424
158625197	158625220	2	-	28162770	OCIAML2	viability	TGGGGACCCCACTCTGGCGGTGG	PKP4	ENSG00000144283	-0.48790781667399674	[41]	[165]	-4	hSpCas9	negative selection	12244425
158625210	158625233	2	+	28162770	OCIAML2	viability	GGGGTCCCCACTGACCCTGACGG	PKP4	ENSG00000144283	0.46225597889930187	[43]	[335]	4	hSpCas9	negative selection	12244426
158631799	158631822	2	-	28162770	OCIAML2	viability	CGGGAGACACGGCAGAACGAAGG	PKP4	ENSG00000144283	0.1668000953731305	[26]	[167]	1	hSpCas9	negative selection	12244427
158631869	158631892	2	+	28162770	OCIAML2	viability	GTGTACCGCAGCCCAAACCATGG	PKP4	ENSG00000144283	-0.021550752602778056	[88]	[485]	0	hSpCas9	negative selection	12244428
158533235	158533258	2	-	28162770	OCIAML3	viability	CAGTGGAGGCAGCTTCCTGGCGG	PKP4	ENSG00000144283	0.0038074624690562775	[148]	[450]	0	hSpCas9	negative selection	12413789
158533188	158533211	2	-	28162770	OCIAML3	viability	AATGAGGCCTGCTCAGGAGCTGG	PKP4	ENSG00000144283	0.9407691032287764	[38]	[225]	7	hSpCas9	negative selection	12413790
158625197	158625220	2	-	28162770	OCIAML3	viability	TGGGGACCCCACTCTGGCGGTGG	PKP4	ENSG00000144283	-0.07223896609020086	[69]	[200]	0	hSpCas9	negative selection	12413791
158625210	158625233	2	+	28162770	OCIAML3	viability	GGGGTCCCCACTGACCCTGACGG	PKP4	ENSG00000144283	0.1454011297703718	[58]	[196]	1	hSpCas9	negative selection	12413792
158631799	158631822	2	-	28162770	OCIAML3	viability	CGGGAGACACGGCAGAACGAAGG	PKP4	ENSG00000144283	1.0784177016473324	[39]	[254]	8	hSpCas9	negative selection	12413793
158631869	158631892	2	+	28162770	OCIAML3	viability	GTGTACCGCAGCCCAAACCATGG	PKP4	ENSG00000144283	0.9994413262848214	[112]	[681]	8	hSpCas9	negative selection	12413794