Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:5335
• Symbol:PLCG1
• Description:phospholipase C gamma 1

DataSource: http://genomecrispr.dkfz.de/#!/results/PLCG1

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
41172200	41172223	20	+	26472758	Jiyoye	viability	AAGGGAAGATAATGGAACGGAGG	PLCG1	ENSG00000124181	0.30826035543318614	[165]	[154]	2	hSpCas9	negative selection	121862
41166811	41166834	20	+	26472758	Jiyoye	viability	GCTGCGCTATCCCATCAACGAGG	PLCG1	ENSG00000124181	0.5033906967651764	[57]	[61]	4	hSpCas9	negative selection	121863
41137739	41137762	20	-	26472758	Jiyoye	viability	GGAGTAGAACAAAGTCATGACGG	PLCG1	ENSG00000124181	0.3309397956787883	[135]	[128]	2	hSpCas9	negative selection	121864
41159617	41159640	20	+	26472758	Jiyoye	viability	GAAATTAAGGAGATCCGCCCAGG	PLCG1	ENSG00000124181	1.0286637582521434	[129]	[199]	6	hSpCas9	negative selection	121865
41162670	41162693	20	-	26472758	Jiyoye	viability	CAGCTGAGCAAACTGCCCGTAGG	PLCG1	ENSG00000124181	0.0898836967392298	[232]	[186]	0	hSpCas9	negative selection	121866
41162963	41162986	20	-	26472758	Jiyoye	viability	TACTGGCTTCCAAGAAGGGGAGG	PLCG1	ENSG00000124181	-0.048019244244953185	[84]	[61]	0	hSpCas9	negative selection	121867
41163235	41163258	20	-	26472758	Jiyoye	viability	GAACTGCTGGAACTCAGGAAGGG	PLCG1	ENSG00000124181	0.2759308482276208	[45]	[41]	2	hSpCas9	negative selection	121868
41165020	41165043	20	+	26472758	Jiyoye	viability	CACACTCCTCACCAAGCCCGTGG	PLCG1	ENSG00000124181	-0.29736873496795524	[43]	[26]	-2	hSpCas9	negative selection	121869
41165259	41165282	20	+	26472758	Jiyoye	viability	TGAGGGCAGTGCCTACGAGGAGG	PLCG1	ENSG00000124181	0.48809537688944066	[155]	[164]	3	hSpCas9	negative selection	121870
41165530	41165553	20	+	26472758	Jiyoye	viability	GGATGAGGAGGAGCCCAAGGAGG	PLCG1	ENSG00000124181	-0.39119075732447595	[39]	[22]	-3	hSpCas9	negative selection	121871
41172200	41172223	20	+	26472758	KBM7	viability	AAGGGAAGATAATGGAACGGAGG	PLCG1	ENSG00000124181	0.5054224310765487	[745,632]	[607,324]	5	hSpCas9	negative selection	312980
41166811	41166834	20	+	26472758	KBM7	viability	GCTGCGCTATCCCATCAACGAGG	PLCG1	ENSG00000124181	0.029254272350580646	[252,178]	[114,90]	0	hSpCas9	negative selection	312981
41137739	41137762	20	-	26472758	KBM7	viability	GGAGTAGAACAAAGTCATGACGG	PLCG1	ENSG00000124181	0.22190763392595733	[610,495]	[239,356]	2	hSpCas9	negative selection	312982
41159617	41159640	20	+	26472758	KBM7	viability	GAAATTAAGGAGATCCGCCCAGG	PLCG1	ENSG00000124181	0.5129699348484567	[632,514]	[449,322]	5	hSpCas9	negative selection	312983
41162670	41162693	20	-	26472758	KBM7	viability	CAGCTGAGCAAACTGCCCGTAGG	PLCG1	ENSG00000124181	0.22449672583900349	[1091,593]	[519,389]	2	hSpCas9	negative selection	312984
41162963	41162986	20	-	26472758	KBM7	viability	TACTGGCTTCCAAGAAGGGGAGG	PLCG1	ENSG00000124181	0.047148190119411404	[283,226]	[107,136]	0	hSpCas9	negative selection	312985
41163235	41163258	20	-	26472758	KBM7	viability	GAACTGCTGGAACTCAGGAAGGG	PLCG1	ENSG00000124181	0.3216348157986316	[233,280]	[191,118]	3	hSpCas9	negative selection	312986
41165020	41165043	20	+	26472758	KBM7	viability	CACACTCCTCACCAAGCCCGTGG	PLCG1	ENSG00000124181	0.7201684136133161	[271,246]	[153,242]	7	hSpCas9	negative selection	312987
41165259	41165282	20	+	26472758	KBM7	viability	TGAGGGCAGTGCCTACGAGGAGG	PLCG1	ENSG00000124181	-0.4077099315718806	[785,787]	[358,209]	-4	hSpCas9	negative selection	312988
41165530	41165553	20	+	26472758	KBM7	viability	GGATGAGGAGGAGCCCAAGGAGG	PLCG1	ENSG00000124181	-0.4271981902687889	[141,85]	[37,39]	-4	hSpCas9	negative selection	312989
41172200	41172223	20	+	26472758	Raji	viability	AAGGGAAGATAATGGAACGGAGG	PLCG1	ENSG00000124181	0.7022888393423341	[240]	[90]	6	hSpCas9	negative selection	504098
41166811	41166834	20	+	26472758	Raji	viability	GCTGCGCTATCCCATCAACGAGG	PLCG1	ENSG00000124181	-0.11968537317232153	[102]	[21]	-1	hSpCas9	negative selection	504099
41137739	41137762	20	-	26472758	Raji	viability	GGAGTAGAACAAAGTCATGACGG	PLCG1	ENSG00000124181	0.23579980850103366	[332]	[90]	2	hSpCas9	negative selection	504100
41159617	41159640	20	+	26472758	Raji	viability	GAAATTAAGGAGATCCGCCCAGG	PLCG1	ENSG00000124181	0.6187649037136482	[361]	[128]	6	hSpCas9	negative selection	504101
41162670	41162693	20	-	26472758	Raji	viability	CAGCTGAGCAAACTGCCCGTAGG	PLCG1	ENSG00000124181	0.17883405863530777	[452]	[118]	1	hSpCas9	negative selection	504102
41162963	41162986	20	-	26472758	Raji	viability	TACTGGCTTCCAAGAAGGGGAGG	PLCG1	ENSG00000124181	-1.9735364600099679	[219]	[12]	-8	hSpCas9	negative selection	504103
41163235	41163258	20	-	26472758	Raji	viability	GAACTGCTGGAACTCAGGAAGGG	PLCG1	ENSG00000124181	0.2814129351486484	[116]	[32]	2	hSpCas9	negative selection	504104
41165020	41165043	20	+	26472758	Raji	viability	CACACTCCTCACCAAGCCCGTGG	PLCG1	ENSG00000124181	0.744813455988891	[143]	[55]	7	hSpCas9	negative selection	504105
41165259	41165282	20	+	26472758	Raji	viability	TGAGGGCAGTGCCTACGAGGAGG	PLCG1	ENSG00000124181	0.022991348083226892	[351]	[82]	0	hSpCas9	negative selection	504106
41165530	41165553	20	+	26472758	Raji	viability	GGATGAGGAGGAGCCCAAGGAGG	PLCG1	ENSG00000124181	-0.02189948157136712	[69]	[15]	0	hSpCas9	negative selection	504107
41172200	41172223	20	+	26472758	K562	viability	AAGGGAAGATAATGGAACGGAGG	PLCG1	ENSG00000124181	-0.4168389534473849	[562]	[355]	-3	hSpCas9	negative selection	695216
41166811	41166834	20	+	26472758	K562	viability	GCTGCGCTATCCCATCAACGAGG	PLCG1	ENSG00000124181	0.2030779322855475	[176]	[171]	1	hSpCas9	negative selection	695217
41137739	41137762	20	-	26472758	K562	viability	GGAGTAGAACAAAGTCATGACGG	PLCG1	ENSG00000124181	0.30213422552273417	[587]	[611]	2	hSpCas9	negative selection	695218
41159617	41159640	20	+	26472758	K562	viability	GAAATTAAGGAGATCCGCCCAGG	PLCG1	ENSG00000124181	0.004467934945694418	[495]	[419]	0	hSpCas9	negative selection	695219
41162670	41162693	20	-	26472758	K562	viability	CAGCTGAGCAAACTGCCCGTAGG	PLCG1	ENSG00000124181	0.003410628162651891	[454]	[384]	0	hSpCas9	negative selection	695220
41162963	41162986	20	-	26472758	K562	viability	TACTGGCTTCCAAGAAGGGGAGG	PLCG1	ENSG00000124181	0.9570087465633165	[190]	[312]	7	hSpCas9	negative selection	695221
41163235	41163258	20	-	26472758	K562	viability	GAACTGCTGGAACTCAGGAAGGG	PLCG1	ENSG00000124181	-2.0344406453290294	[164]	[33]	-7	hSpCas9	negative selection	695222
41165020	41165043	20	+	26472758	K562	viability	CACACTCCTCACCAAGCCCGTGG	PLCG1	ENSG00000124181	0.820993442894884	[229]	[342]	6	hSpCas9	negative selection	695223
41165259	41165282	20	+	26472758	K562	viability	TGAGGGCAGTGCCTACGAGGAGG	PLCG1	ENSG00000124181	1.0408853335813149	[531]	[923]	8	hSpCas9	negative selection	695224
41165530	41165553	20	+	26472758	K562	viability	GGATGAGGAGGAGCCCAAGGAGG	PLCG1	ENSG00000124181	-2.2003661150064495	[97]	[17]	-7	hSpCas9	negative selection	695225
41137833	41137856	20	+	26627737	DLD1	viability	GGGCGCCGACAAGATCGAGGGGG	PLCG1	ENSG00000124181	-0.1530156129711997	[209]	[59,45,68]	-2	hSpCas9	negative selection	814547
41159618	41159641	20	+	26627737	DLD1	viability	AAATTAAGGAGATCCGCCCAGGG	PLCG1	ENSG00000124181	-0.290238509139203	[145]	[35,55,22]	-3	hSpCas9	negative selection	814548
41160102	41160125	20	-	26627737	DLD1	viability	AAACTGCTTCCGGAGCCACCTGG	PLCG1	ENSG00000124181	1.6019420490821163	[117]	[155,153,38]	9	hSpCas9	negative selection	814549
41162626	41162649	20	+	26627737	DLD1	viability	GCTCTATACCATGCAGGACCTGG	PLCG1	ENSG00000124181	0.8756417423193155	[378]	[176,183,279]	8	hSpCas9	negative selection	814550
41162966	41162989	20	-	26627737	DLD1	viability	GAGTACTGGCTTCCAAGAAGGGG	PLCG1	ENSG00000124181	0.652418867059832	[353]	[91,290,147]	6	hSpCas9	negative selection	814551
41163252	41163275	20	+	26627737	DLD1	viability	CAGTTCCTTCTTGACTACCAGGG	PLCG1	ENSG00000124181	0.8016934183060425	[330]	[143,242,159]	7	hSpCas9	negative selection	814552
41137833	41137856	20	+	26627737	GBM cells	viability after 5 days	GGGCGCCGACAAGATCGAGGGGG	PLCG1	ENSG00000124181	-0.1823862272161626	[145]	[76,60]	-3	hSpCas9	negative selection	896862
41159618	41159641	20	+	26627737	GBM cells	viability after 5 days	AAATTAAGGAGATCCGCCCAGGG	PLCG1	ENSG00000124181	-0.21741024308154644	[141]	[50,79]	-3	hSpCas9	negative selection	896863
41160102	41160125	20	-	26627737	GBM cells	viability after 5 days	AAACTGCTTCCGGAGCCACCTGG	PLCG1	ENSG00000124181	0.22275155978167926	[150]	[104,83]	3	hSpCas9	negative selection	896864
41162626	41162649	20	+	26627737	GBM cells	viability after 5 days	GCTCTATACCATGCAGGACCTGG	PLCG1	ENSG00000124181	0.13682368656386318	[250]	[165,129]	2	hSpCas9	negative selection	896865
41162966	41162989	20	-	26627737	GBM cells	viability after 5 days	GAGTACTGGCTTCCAAGAAGGGG	PLCG1	ENSG00000124181	-0.26335755401319166	[281]	[119,131]	-4	hSpCas9	negative selection	896866
41163252	41163275	20	+	26627737	GBM cells	viability after 5 days	CAGTTCCTTCTTGACTACCAGGG	PLCG1	ENSG00000124181	-0.08508564642059926	[268]	[148,122]	-1	hSpCas9	negative selection	896867
41137833	41137856	20	+	26627737	GBM cells	viability after 13 days	GGGCGCCGACAAGATCGAGGGGG	PLCG1	ENSG00000124181	-1.0701599663604937	[145]	[45,30]	-8	hSpCas9	negative selection	979177
41159618	41159641	20	+	26627737	GBM cells	viability after 13 days	AAATTAAGGAGATCCGCCCAGGG	PLCG1	ENSG00000124181	-1.5257805013349075	[141]	[23,28]	-9	hSpCas9	negative selection	979178
41160102	41160125	20	-	26627737	GBM cells	viability after 13 days	AAACTGCTTCCGGAGCCACCTGG	PLCG1	ENSG00000124181	0.4617165683568763	[150]	[119,106]	6	hSpCas9	negative selection	979179
41162626	41162649	20	+	26627737	GBM cells	viability after 13 days	GCTCTATACCATGCAGGACCTGG	PLCG1	ENSG00000124181	-0.44696394685139634	[250]	[116,85]	-5	hSpCas9	negative selection	979180
41162966	41162989	20	-	26627737	GBM cells	viability after 13 days	GAGTACTGGCTTCCAAGAAGGGG	PLCG1	ENSG00000124181	-0.8668998988946416	[281]	[84,82]	-7	hSpCas9	negative selection	979181
41163252	41163275	20	+	26627737	GBM cells	viability after 13 days	CAGTTCCTTCTTGACTACCAGGG	PLCG1	ENSG00000124181	-0.7157728535288448	[268]	[100,78]	-7	hSpCas9	negative selection	979182
41137833	41137856	20	+	26627737	GBM cells	viability after 21 days	GGGCGCCGACAAGATCGAGGGGG	PLCG1	ENSG00000124181	-1.63590921421611	[145]	[24,25]	-8	hSpCas9	negative selection	1061492
41159618	41159641	20	+	26627737	GBM cells	viability after 21 days	AAATTAAGGAGATCCGCCCAGGG	PLCG1	ENSG00000124181	-1.5241569554636767	[141]	[30,22]	-8	hSpCas9	negative selection	1061493
41160102	41160125	20	-	26627737	GBM cells	viability after 21 days	AAACTGCTTCCGGAGCCACCTGG	PLCG1	ENSG00000124181	-0.15305700980480796	[150]	[78,68]	-1	hSpCas9	negative selection	1061494
41162626	41162649	20	+	26627737	GBM cells	viability after 21 days	GCTCTATACCATGCAGGACCTGG	PLCG1	ENSG00000124181	0.34942051862450235	[250]	[179,167]	3	hSpCas9	negative selection	1061495
41162966	41162989	20	-	26627737	GBM cells	viability after 21 days	GAGTACTGGCTTCCAAGAAGGGG	PLCG1	ENSG00000124181	-0.8337990696359688	[281]	[86,84]	-6	hSpCas9	negative selection	1061496
41163252	41163275	20	+	26627737	GBM cells	viability after 21 days	CAGTTCCTTCTTGACTACCAGGG	PLCG1	ENSG00000124181	-1.1357055957725397	[268]	[77,55]	-7	hSpCas9	negative selection	1061497
41137833	41137856	20	+	26627737	RPE1	viability after 9 days	GGGCGCCGACAAGATCGAGGGGG	PLCG1	ENSG00000124181	1.9770604052503504	[109]	[111,165]	8	hSpCas9	negative selection	1143807
41159618	41159641	20	+	26627737	RPE1	viability after 9 days	AAATTAAGGAGATCCGCCCAGGG	PLCG1	ENSG00000124181	0.12187330348791803	[234]	[76,83]	0	hSpCas9	negative selection	1143808
41160102	41160125	20	-	26627737	RPE1	viability after 9 days	AAACTGCTTCCGGAGCCACCTGG	PLCG1	ENSG00000124181	0.3970073340834708	[378]	[181,122]	2	hSpCas9	negative selection	1143809
41162626	41162649	20	+	26627737	RPE1	viability after 9 days	GCTCTATACCATGCAGGACCTGG	PLCG1	ENSG00000124181	1.2329360019398385	[337]	[201,308]	7	hSpCas9	negative selection	1143810
41162966	41162989	20	-	26627737	RPE1	viability after 9 days	GAGTACTGGCTTCCAAGAAGGGG	PLCG1	ENSG00000124181	-0.980632211034167	[1411]	[168,294]	-6	hSpCas9	negative selection	1143811
41163252	41163275	20	+	26627737	RPE1	viability after 9 days	CAGTTCCTTCTTGACTACCAGGG	PLCG1	ENSG00000124181	-0.7998705958799393	[972]	[129,232]	-5	hSpCas9	negative selection	1143812
41137833	41137856	20	+	26627737	RPE1	viability after 12 days	GGGCGCCGACAAGATCGAGGGGG	PLCG1	ENSG00000124181	2.755926106135534	[109]	[152,248]	9	hSpCas9	negative selection	1226122
41159618	41159641	20	+	26627737	RPE1	viability after 12 days	AAATTAAGGAGATCCGCCCAGGG	PLCG1	ENSG00000124181	0.5605250849017358	[234]	[79,106]	3	hSpCas9	negative selection	1226123
41160102	41160125	20	-	26627737	RPE1	viability after 12 days	AAACTGCTTCCGGAGCCACCTGG	PLCG1	ENSG00000124181	0.8502550955256826	[378]	[236,126]	5	hSpCas9	negative selection	1226124
41162626	41162649	20	+	26627737	RPE1	viability after 12 days	GCTCTATACCATGCAGGACCTGG	PLCG1	ENSG00000124181	0.823842795760687	[337]	[236,79]	5	hSpCas9	negative selection	1226125
41162966	41162989	20	-	26627737	RPE1	viability after 12 days	GAGTACTGGCTTCCAAGAAGGGG	PLCG1	ENSG00000124181	-0.6643058096764856	[1411]	[200,279]	-4	hSpCas9	negative selection	1226126
41163252	41163275	20	+	26627737	RPE1	viability after 12 days	CAGTTCCTTCTTGACTACCAGGG	PLCG1	ENSG00000124181	-0.46990634576741497	[972]	[111,269]	-3	hSpCas9	negative selection	1226127
41137833	41137856	20	+	26627737	RPE1	viability after 15 days	GGGCGCCGACAAGATCGAGGGGG	PLCG1	ENSG00000124181	2.0397515163434274	[109]	[102,151]	8	hSpCas9	negative selection	1308437
41159618	41159641	20	+	26627737	RPE1	viability after 15 days	AAATTAAGGAGATCCGCCCAGGG	PLCG1	ENSG00000124181	0.2966808650711801	[234]	[72,89]	2	hSpCas9	negative selection	1308438
41160102	41160125	20	-	26627737	RPE1	viability after 15 days	AAACTGCTTCCGGAGCCACCTGG	PLCG1	ENSG00000124181	1.6708725788473733	[378]	[601,89]	8	hSpCas9	negative selection	1308439
41162626	41162649	20	+	26627737	RPE1	viability after 15 days	GCTCTATACCATGCAGGACCTGG	PLCG1	ENSG00000124181	0.7875476823660761	[337]	[218,112]	5	hSpCas9	negative selection	1308440
41162966	41162989	20	-	26627737	RPE1	viability after 15 days	GAGTACTGGCTTCCAAGAAGGGG	PLCG1	ENSG00000124181	-0.512224391770794	[1411]	[248,309]	-3	hSpCas9	negative selection	1308441
41163252	41163275	20	+	26627737	RPE1	viability after 15 days	CAGTTCCTTCTTGACTACCAGGG	PLCG1	ENSG00000124181	-0.6609097196112357	[972]	[84,259]	-4	hSpCas9	negative selection	1308442
41137833	41137856	20	+	26627737	RPE1	viability after 18 days	GGGCGCCGACAAGATCGAGGGGG	PLCG1	ENSG00000124181	2.222470276496386	[109]	[197,74]	9	hSpCas9	negative selection	1390752
41159618	41159641	20	+	26627737	RPE1	viability after 18 days	AAATTAAGGAGATCCGCCCAGGG	PLCG1	ENSG00000124181	-0.043500590623471114	[234]	[47,75]	0	hSpCas9	negative selection	1390753
41160102	41160125	20	-	26627737	RPE1	viability after 18 days	AAACTGCTTCCGGAGCCACCTGG	PLCG1	ENSG00000124181	0.7867705286278144	[378]	[247,99]	5	hSpCas9	negative selection	1390754
41162626	41162649	20	+	26627737	RPE1	viability after 18 days	GCTCTATACCATGCAGGACCTGG	PLCG1	ENSG00000124181	0.1366734602067068	[337]	[122,75]	0	hSpCas9	negative selection	1390755
41162966	41162989	20	-	26627737	RPE1	viability after 18 days	GAGTACTGGCTTCCAAGAAGGGG	PLCG1	ENSG00000124181	-0.7579796362669802	[1411]	[263,183]	-5	hSpCas9	negative selection	1390756
41163252	41163275	20	+	26627737	RPE1	viability after 18 days	CAGTTCCTTCTTGACTACCAGGG	PLCG1	ENSG00000124181	-0.7645231500910251	[972]	[39,276]	-5	hSpCas9	negative selection	1390757
41137833	41137856	20	+	26627737	HeLa	viability after 8 days	GGGCGCCGACAAGATCGAGGGGG	PLCG1	ENSG00000124181	-0.5110811714839238	[145]	[48,0,81]	-5	hSpCas9	negative selection	1473067
41159618	41159641	20	+	26627737	HeLa	viability after 8 days	AAATTAAGGAGATCCGCCCAGGG	PLCG1	ENSG00000124181	0.05816728048786901	[190]	[143,52,75]	0	hSpCas9	negative selection	1473068
41160102	41160125	20	-	26627737	HeLa	viability after 8 days	AAACTGCTTCCGGAGCCACCTGG	PLCG1	ENSG00000124181	-0.2830853123569649	[222]	[176,23,60]	-3	hSpCas9	negative selection	1473069
41162626	41162649	20	+	26627737	HeLa	viability after 8 days	GCTCTATACCATGCAGGACCTGG	PLCG1	ENSG00000124181	-1.2317152312939619	[344]	[33,128,24]	-8	hSpCas9	negative selection	1473070
41162966	41162989	20	-	26627737	HeLa	viability after 8 days	GAGTACTGGCTTCCAAGAAGGGG	PLCG1	ENSG00000124181	-0.6624206022458592	[429]	[134,99,122]	-6	hSpCas9	negative selection	1473071
41163252	41163275	20	+	26627737	HeLa	viability after 8 days	CAGTTCCTTCTTGACTACCAGGG	PLCG1	ENSG00000124181	-0.30721464891752037	[487]	[193,112,209]	-3	hSpCas9	negative selection	1473072
41137833	41137856	20	+	26627737	HeLa	viability after 12 days	GGGCGCCGACAAGATCGAGGGGG	PLCG1	ENSG00000124181	0.1168621735044093	[145]	[111,61,23]	1	hSpCas9	negative selection	1555382
41159618	41159641	20	+	26627737	HeLa	viability after 12 days	AAATTAAGGAGATCCGCCCAGGG	PLCG1	ENSG00000124181	-1.5829640358010366	[190]	[21,34,20]	-8	hSpCas9	negative selection	1555383
41160102	41160125	20	-	26627737	HeLa	viability after 12 days	AAACTGCTTCCGGAGCCACCTGG	PLCG1	ENSG00000124181	0.28673907825941536	[222]	[80,77,180]	2	hSpCas9	negative selection	1555384
41162626	41162649	20	+	26627737	HeLa	viability after 12 days	GCTCTATACCATGCAGGACCTGG	PLCG1	ENSG00000124181	-0.8025425062431277	[344]	[57,67,119]	-6	hSpCas9	negative selection	1555385
41162966	41162989	20	-	26627737	HeLa	viability after 12 days	GAGTACTGGCTTCCAAGAAGGGG	PLCG1	ENSG00000124181	-0.44508533856983173	[429]	[104,147,135]	-4	hSpCas9	negative selection	1555386
41163252	41163275	20	+	26627737	HeLa	viability after 12 days	CAGTTCCTTCTTGACTACCAGGG	PLCG1	ENSG00000124181	-0.6422882076155927	[487]	[40,110,234]	-5	hSpCas9	negative selection	1555387
41137833	41137856	20	+	26627737	HeLa	viability after 15 days	GGGCGCCGACAAGATCGAGGGGG	PLCG1	ENSG00000124181	-0.9561448416510123	[145]	[0,39,52]	-7	hSpCas9	negative selection	1637697
41159618	41159641	20	+	26627737	HeLa	viability after 15 days	AAATTAAGGAGATCCGCCCAGGG	PLCG1	ENSG00000124181	-1.0076666712019369	[190]	[66,41,3]	-7	hSpCas9	negative selection	1637698
41160102	41160125	20	-	26627737	HeLa	viability after 15 days	AAACTGCTTCCGGAGCCACCTGG	PLCG1	ENSG00000124181	-0.12463878992096933	[222]	[71,69,109]	-1	hSpCas9	negative selection	1637699
41162626	41162649	20	+	26627737	HeLa	viability after 15 days	GCTCTATACCATGCAGGACCTGG	PLCG1	ENSG00000124181	-1.4092991389443297	[344]	[60,38,58]	-8	hSpCas9	negative selection	1637700
41162966	41162989	20	-	26627737	HeLa	viability after 15 days	GAGTACTGGCTTCCAAGAAGGGG	PLCG1	ENSG00000124181	-0.2533039589305681	[429]	[136,68,241]	-2	hSpCas9	negative selection	1637701
41163252	41163275	20	+	26627737	HeLa	viability after 15 days	CAGTTCCTTCTTGACTACCAGGG	PLCG1	ENSG00000124181	-0.39461641450530466	[487]	[51,198,207]	-3	hSpCas9	negative selection	1637702
41137833	41137856	20	+	26627737	HeLa	viability after 18 days	GGGCGCCGACAAGATCGAGGGGG	PLCG1	ENSG00000124181	-0.9124554510756633	[145]	[0,34,52]	-7	hSpCas9	negative selection	1720012
41159618	41159641	20	+	26627737	HeLa	viability after 18 days	AAATTAAGGAGATCCGCCCAGGG	PLCG1	ENSG00000124181	-0.9180027379159377	[190]	[47,36,3]	-7	hSpCas9	negative selection	1720013
41160102	41160125	20	-	26627737	HeLa	viability after 18 days	AAACTGCTTCCGGAGCCACCTGG	PLCG1	ENSG00000124181	-0.09535872546822766	[222]	[49,59,109]	-1	hSpCas9	negative selection	1720014
41162626	41162649	20	+	26627737	HeLa	viability after 18 days	GCTCTATACCATGCAGGACCTGG	PLCG1	ENSG00000124181	-1.4031886627863848	[344]	[39,33,58]	-8	hSpCas9	negative selection	1720015
41162966	41162989	20	-	26627737	HeLa	viability after 18 days	GAGTACTGGCTTCCAAGAAGGGG	PLCG1	ENSG00000124181	-0.24338734040607568	[429]	[93,56,241]	-2	hSpCas9	negative selection	1720016
41163252	41163275	20	+	26627737	HeLa	viability after 18 days	CAGTTCCTTCTTGACTACCAGGG	PLCG1	ENSG00000124181	-0.4020560674060968	[487]	[33,163,207]	-3	hSpCas9	negative selection	1720017
41137833	41137856	20	+	26627737	HCT116	viability after 6 days	GGGCGCCGACAAGATCGAGGGGG	PLCG1	ENSG00000124181	-1.5984116014879777	[590]	[69,8]	-7	hSpCas9	negative selection	1802327
41159618	41159641	20	+	26627737	HCT116	viability after 6 days	AAATTAAGGAGATCCGCCCAGGG	PLCG1	ENSG00000124181	-2.8439691259408715	[270]	[3,6]	-9	hSpCas9	negative selection	1802328
41160102	41160125	20	-	26627737	HCT116	viability after 6 days	AAACTGCTTCCGGAGCCACCTGG	PLCG1	ENSG00000124181	2.207744376753109	[102]	[204,2]	9	hSpCas9	negative selection	1802329
41162626	41162649	20	+	26627737	HCT116	viability after 6 days	GCTCTATACCATGCAGGACCTGG	PLCG1	ENSG00000124181	2.2138704083181833	[260]	[83,248]	9	hSpCas9	negative selection	1802330
41162966	41162989	20	-	26627737	HCT116	viability after 6 days	GAGTACTGGCTTCCAAGAAGGGG	PLCG1	ENSG00000124181	-3.1734009114005315	[791]	[7,16]	-9	hSpCas9	negative selection	1802331
41163252	41163275	20	+	26627737	HCT116	viability after 6 days	CAGTTCCTTCTTGACTACCAGGG	PLCG1	ENSG00000124181	-1.0171786951456472	[693]	[89,33]	-5	hSpCas9	negative selection	1802332
41137833	41137856	20	+	26627737	HCT116	viability after 8 days	GGGCGCCGACAAGATCGAGGGGG	PLCG1	ENSG00000124181	-1.7130257927829762	[344]	[56,63,52]	-9	hSpCas9	negative selection	1884642
41159618	41159641	20	+	26627737	HCT116	viability after 8 days	AAATTAAGGAGATCCGCCCAGGG	PLCG1	ENSG00000124181	-0.3043028681250153	[125]	[37,44,84]	-4	hSpCas9	negative selection	1884643
41160102	41160125	20	-	26627737	HCT116	viability after 8 days	AAACTGCTTCCGGAGCCACCTGG	PLCG1	ENSG00000124181	3.9806051961828777	[6]	[68,67,45]	9	hSpCas9	negative selection	1884644
41162626	41162649	20	+	26627737	HCT116	viability after 8 days	GCTCTATACCATGCAGGACCTGG	PLCG1	ENSG00000124181	0.07192071346118653	[288]	[218,109,173]	0	hSpCas9	negative selection	1884645
41162966	41162989	20	-	26627737	HCT116	viability after 8 days	GAGTACTGGCTTCCAAGAAGGGG	PLCG1	ENSG00000124181	-0.3898153646518462	[412]	[139,167,211]	-4	hSpCas9	negative selection	1884646
41163252	41163275	20	+	26627737	HCT116	viability after 8 days	CAGTTCCTTCTTGACTACCAGGG	PLCG1	ENSG00000124181	0.30817732167237344	[168]	[108,138,97]	3	hSpCas9	negative selection	1884647
41137833	41137856	20	+	26627737	HCT116	viability after 9 days	GGGCGCCGACAAGATCGAGGGGG	PLCG1	ENSG00000124181	-2.2380707753194296	[590]	[52,17]	-9	hSpCas9	negative selection	1966957
41159618	41159641	20	+	26627737	HCT116	viability after 9 days	AAATTAAGGAGATCCGCCCAGGG	PLCG1	ENSG00000124181	-1.475720069463338	[270]	[1,44]	-8	hSpCas9	negative selection	1966958
41160102	41160125	20	-	26627737	HCT116	viability after 9 days	AAACTGCTTCCGGAGCCACCTGG	PLCG1	ENSG00000124181	3.2453491455841057	[102]	[47,428]	9	hSpCas9	negative selection	1966959
41162626	41162649	20	+	26627737	HCT116	viability after 9 days	GCTCTATACCATGCAGGACCTGG	PLCG1	ENSG00000124181	1.0292087523265816	[260]	[77,192]	7	hSpCas9	negative selection	1966960
41162966	41162989	20	-	26627737	HCT116	viability after 9 days	GAGTACTGGCTTCCAAGAAGGGG	PLCG1	ENSG00000124181	-0.9375820931512899	[791]	[115,105]	-6	hSpCas9	negative selection	1966961
41163252	41163275	20	+	26627737	HCT116	viability after 9 days	CAGTTCCTTCTTGACTACCAGGG	PLCG1	ENSG00000124181	-0.2944507927285085	[693]	[49,230]	-2	hSpCas9	negative selection	1966962
41137833	41137856	20	+	26627737	HCT116	viability after 12 days	GGGCGCCGACAAGATCGAGGGGG	PLCG1	ENSG00000124181	-1.9821718099153256	[344]	[42,48,45]	-9	hSpCas9	negative selection	2049272
41159618	41159641	20	+	26627737	HCT116	viability after 12 days	AAATTAAGGAGATCCGCCCAGGG	PLCG1	ENSG00000124181	-0.043263465660905664	[125]	[66,41,82]	0	hSpCas9	negative selection	2049273
41160102	41160125	20	-	26627737	HCT116	viability after 12 days	AAACTGCTTCCGGAGCCACCTGG	PLCG1	ENSG00000124181	4.694392927533886	[6]	[135,129,16]	9	hSpCas9	negative selection	2049274
41162626	41162649	20	+	26627737	HCT116	viability after 12 days	GCTCTATACCATGCAGGACCTGG	PLCG1	ENSG00000124181	0.22660644557571819	[288]	[172,237,123]	2	hSpCas9	negative selection	2049275
41162966	41162989	20	-	26627737	HCT116	viability after 12 days	GAGTACTGGCTTCCAAGAAGGGG	PLCG1	ENSG00000124181	-0.5239303747257225	[412]	[86,131,238]	-5	hSpCas9	negative selection	2049276
41163252	41163275	20	+	26627737	HCT116	viability after 12 days	CAGTTCCTTCTTGACTACCAGGG	PLCG1	ENSG00000124181	0.16539574052945627	[168]	[89,113,95]	1	hSpCas9	negative selection	2049277
41137833	41137856	20	+	26627737	HCT116	viability after 15 days	GGGCGCCGACAAGATCGAGGGGG	PLCG1	ENSG00000124181	-1.4153033270157003	[344]	[154,29,47]	-8	hSpCas9	negative selection	2131587
41159618	41159641	20	+	26627737	HCT116	viability after 15 days	AAATTAAGGAGATCCGCCCAGGG	PLCG1	ENSG00000124181	-1.1012712981814796	[125]	[10,18,67]	-8	hSpCas9	negative selection	2131588
41160102	41160125	20	-	26627737	HCT116	viability after 15 days	AAACTGCTTCCGGAGCCACCTGG	PLCG1	ENSG00000124181	4.917441858792016	[6]	[142,95,127]	9	hSpCas9	negative selection	2131589
41162626	41162649	20	+	26627737	HCT116	viability after 15 days	GCTCTATACCATGCAGGACCTGG	PLCG1	ENSG00000124181	0.49341926126242797	[288]	[382,257,79]	4	hSpCas9	negative selection	2131590
41162966	41162989	20	-	26627737	HCT116	viability after 15 days	GAGTACTGGCTTCCAAGAAGGGG	PLCG1	ENSG00000124181	-0.8643876368103919	[412]	[148,103,139]	-7	hSpCas9	negative selection	2131591
41163252	41163275	20	+	26627737	HCT116	viability after 15 days	CAGTTCCTTCTTGACTACCAGGG	PLCG1	ENSG00000124181	0.5837055943491003	[168]	[111,149,169]	5	hSpCas9	negative selection	2131592
41137833	41137856	20	+	26627737	HCT116	viability after 18 days	GGGCGCCGACAAGATCGAGGGGG	PLCG1	ENSG00000124181	-1.5142517028675235	[344]	[80,41,52]	-8	hSpCas9	negative selection	2213902
41159618	41159641	20	+	26627737	HCT116	viability after 18 days	AAATTAAGGAGATCCGCCCAGGG	PLCG1	ENSG00000124181	-0.2360435645147434	[125]	[9,35,112]	-2	hSpCas9	negative selection	2213903
41160102	41160125	20	-	26627737	HCT116	viability after 18 days	AAACTGCTTCCGGAGCCACCTGG	PLCG1	ENSG00000124181	5.283911310272974	[6]	[195,92,107]	9	hSpCas9	negative selection	2213904
41162626	41162649	20	+	26627737	HCT116	viability after 18 days	GCTCTATACCATGCAGGACCTGG	PLCG1	ENSG00000124181	0.24107710562673362	[288]	[273,157,58]	2	hSpCas9	negative selection	2213905
41162966	41162989	20	-	26627737	HCT116	viability after 18 days	GAGTACTGGCTTCCAAGAAGGGG	PLCG1	ENSG00000124181	-1.3219031291514036	[412]	[38,58,145]	-8	hSpCas9	negative selection	2213906
41163252	41163275	20	+	26627737	HCT116	viability after 18 days	CAGTTCCTTCTTGACTACCAGGG	PLCG1	ENSG00000124181	-0.05354678114435851	[168]	[107,33,97]	0	hSpCas9	negative selection	2213907
41137627	41137650	20	+	24336569	HL60	viability	CCCAGCGTCGGAGCCATGGCGGG	PLCG1	ENSG00000124181	-0.358444789462284	[1184]	[1955]	-3	hSpCas9	negative selection	2284533
41137659	41137682	20	-	24336569	HL60	viability	GCCCGCAGCCGTTGGCGCAAGGG	PLCG1	ENSG00000124181	-0.26222203325738047	[258]	[456]	-2	hSpCas9	negative selection	2284534
41137690	41137713	20	-	24336569	HL60	viability	TGCAGCACCTCGGCGTCCGAGGG	PLCG1	ENSG00000124181	1.5863914084406048	[30]	[196]	9	hSpCas9	negative selection	2284535
41137700	41137723	20	-	24336569	HL60	viability	GCGGCAGAGGTGCAGCACCTCGG	PLCG1	ENSG00000124181	0.7505636905089165	[322]	[1149]	6	hSpCas9	negative selection	2284536
41137710	41137733	20	+	24336569	HL60	viability	GCACCTCTGCCGCAGCCTCGAGG	PLCG1	ENSG00000124181	-0.3093846533188226	[413]	[706]	-3	hSpCas9	negative selection	2284537
41137719	41137742	20	-	24336569	HL60	viability	CGGTGCCCACCTCGAGGCTGCGG	PLCG1	ENSG00000124181	-0.7526276363993565	[1124]	[1412]	-6	hSpCas9	negative selection	2284538
41137725	41137748	20	-	24336569	HL60	viability	TCATGACGGTGCCCACCTCGAGG	PLCG1	ENSG00000124181	0.4283179968904351	[557]	[1588]	4	hSpCas9	negative selection	2284539
41137739	41137762	20	-	24336569	HL60	viability	GGAGTAGAACAAAGTCATGACGG	PLCG1	ENSG00000124181	-0.9536141454835677	[258]	[282]	-7	hSpCas9	negative selection	2284540
41137760	41137783	20	-	24336569	HL60	viability	CTCGGGTCGCTGCGACTTCTTGG	PLCG1	ENSG00000124181	0.5870461913392163	[245]	[781]	5	hSpCas9	negative selection	2284541
41137776	41137799	20	+	24336569	HL60	viability	ACCCGAGCGGAAGACCTTCCAGG	PLCG1	ENSG00000124181	0.3931046020934255	[361]	[1005]	3	hSpCas9	negative selection	2284542
41137627	41137650	20	+	24336569	KBM7	viability	CCCAGCGTCGGAGCCATGGCGGG	PLCG1	ENSG00000124181	0.16229500154584775	[554]	[1693]	1	hSpCas9	negative selection	2351710
41137659	41137682	20	-	24336569	KBM7	viability	GCCCGCAGCCGTTGGCGCAAGGG	PLCG1	ENSG00000124181	0.05226669053432287	[319]	[904]	0	hSpCas9	negative selection	2351711
41137690	41137713	20	-	24336569	KBM7	viability	TGCAGCACCTCGGCGTCCGAGGG	PLCG1	ENSG00000124181	-0.05944957073355561	[114]	[300]	0	hSpCas9	negative selection	2351712
41137700	41137723	20	-	24336569	KBM7	viability	GCGGCAGAGGTGCAGCACCTCGG	PLCG1	ENSG00000124181	-0.013223520070259676	[305]	[826]	0	hSpCas9	negative selection	2351713
41137710	41137733	20	+	24336569	KBM7	viability	GCACCTCTGCCGCAGCCTCGAGG	PLCG1	ENSG00000124181	0.23504656339041763	[256]	[824]	2	hSpCas9	negative selection	2351714
41137719	41137742	20	-	24336569	KBM7	viability	CGGTGCCCACCTCGAGGCTGCGG	PLCG1	ENSG00000124181	-0.4817949118867954	[767]	[1499]	-4	hSpCas9	negative selection	2351715
41137725	41137748	20	-	24336569	KBM7	viability	TCATGACGGTGCCCACCTCGAGG	PLCG1	ENSG00000124181	-0.25451085469237855	[638]	[1460]	-2	hSpCas9	negative selection	2351716
41137739	41137762	20	-	24336569	KBM7	viability	GGAGTAGAACAAAGTCATGACGG	PLCG1	ENSG00000124181	-0.7775609258749538	[246]	[392]	-5	hSpCas9	negative selection	2351717
41137760	41137783	20	-	24336569	KBM7	viability	CTCGGGTCGCTGCGACTTCTTGG	PLCG1	ENSG00000124181	0.4983394048783575	[264]	[1020]	4	hSpCas9	negative selection	2351718
41137776	41137799	20	+	24336569	KBM7	viability	ACCCGAGCGGAAGACCTTCCAGG	PLCG1	ENSG00000124181	0.761551887152917	[241]	[1118]	6	hSpCas9	negative selection	2351719
41137351	41137374	20	-	25494202	A375	resistance to PLX-4720 (puromycin)	CCCCAGACAGGCCGCAGGCGGGG	PLCG1	ENSG00000124181	0.4114967241637273	[11,4]	[1,1]	1	dCas9-VP64	positive selection	2430856
41137402	41137425	20	+	25494202	A375	resistance to PLX-4720 (puromycin)	CGGGCGGGGGTCCTCCCCACGGG	PLCG1	ENSG00000124181	-1.5389966101903636	[91,302]	[8,20]	-8	dCas9-VP64	positive selection	2430857
41137425	41137448	20	+	25494202	A375	resistance to PLX-4720 (puromycin)	TGCGCGGGCGCCTTTGTTCCCGG	PLCG1	ENSG00000124181	-0.22209845046354593	[209,69]	[44,5]	-1	dCas9-VP64	positive selection	2430858
41137351	41137374	20	-	25494202	A375	resistance to PLX-4720 (zeocin)	CCCCAGACAGGCCGCAGGCGGGG	PLCG1	ENSG00000124181	-0.03884703719814531	[85,21]	[28,4]	0	dCas9-VP64	positive selection	2526111
41137402	41137425	20	+	25494202	A375	resistance to PLX-4720 (zeocin)	CGGGCGGGGGTCCTCCCCACGGG	PLCG1	ENSG00000124181	-0.9987015157734509	[157,49]	[24,8]	-8	dCas9-VP64	positive selection	2526112
41137425	41137448	20	+	25494202	A375	resistance to PLX-4720 (zeocin)	TGCGCGGGCGCCTTTGTTCCCGG	PLCG1	ENSG00000124181	2.3935445542251967	[144,64]	[363,10]	9	dCas9-VP64	positive selection	2526113
41159617	41159640	20	+	27260157	DLD1	viability	GAAATTAAGGAGATCCGCCCAGG	PLCG1	ENSG00000124181	-0.288202057604385	[]	[]	-2	hSpCas9	negative selection	2577015
41159689	41159712	20	-	27260157	DLD1	viability	ACAAAGCAATGTGACTGGTCCGG	PLCG1	ENSG00000124181	0.485167709064192	[]	[]	8	hSpCas9	negative selection	2578088
41137739	41137762	20	-	27260157	DLD1	viability	GGAGTAGAACAAAGTCATGACGG	PLCG1	ENSG00000124181	-0.0507291700062954	[]	[]	0	hSpCas9	negative selection	2578678
41160127	41160150	20	+	27260157	DLD1	viability	CTCAGTGGATCGGAATCGTGAGG	PLCG1	ENSG00000124181	0.0813270965360032	[]	[]	3	hSpCas9	negative selection	2579051
41137700	41137723	20	-	27260157	DLD1	viability	GCGGCAGAGGTGCAGCACCTCGG	PLCG1	ENSG00000124181	-0.0631528378109416	[]	[]	0	hSpCas9	negative selection	2581100
41137790	41137813	20	-	27260157	DLD1	viability	CGTCTCCAGCTTGACCTGGAAGG	PLCG1	ENSG00000124181	1.38575161638418	[]	[]	9	hSpCas9	negative selection	2583514
41137627	41137650	20	+	27260157	DLD1	viability	CCCAGCGTCGGAGCCATGGCGGG	PLCG1	ENSG00000124181	0.813492888068748	[]	[]	9	hSpCas9	negative selection	2583822
41137659	41137682	20	-	27260157	DLD1	viability	GCCCGCAGCCGTTGGCGCAAGGG	PLCG1	ENSG00000124181	0.512633463476785	[]	[]	8	hSpCas9	negative selection	2587443
41137725	41137748	20	-	27260157	DLD1	viability	TCATGACGGTGCCCACCTCGAGG	PLCG1	ENSG00000124181	-1.75281258867435	[]	[]	-8	hSpCas9	negative selection	2612781
41159676	41159699	20	-	27260157	DLD1	viability	ACTGGTCCGGCCGGAAAGCTGGG	PLCG1	ENSG00000124181	0.879597993587599	[]	[]	9	hSpCas9	negative selection	2616080
41162467	41162490	20	+	27260157	DLD1	viability	CCTGAAGAACATGCTGTCCCAGG	PLCG1	ENSG00000124181	0.752691116449962	[]	[]	8	hSpCas9	negative selection	2618530
41137719	41137742	20	-	27260157	DLD1	viability	CGGTGCCCACCTCGAGGCTGCGG	PLCG1	ENSG00000124181	-1.25978922543523	[]	[]	-7	hSpCas9	negative selection	2644912
41137710	41137733	20	+	27260157	DLD1	viability	GCACCTCTGCCGCAGCCTCGAGG	PLCG1	ENSG00000124181	-0.797736731374234	[]	[]	-6	hSpCas9	negative selection	2647192
41137690	41137713	20	-	27260157	DLD1	viability	TGCAGCACCTCGGCGTCCGAGGG	PLCG1	ENSG00000124181	0.0402515284357317	[]	[]	0	hSpCas9	negative selection	2647897
41137805	41137828	20	+	27260157	DLD1	viability	TGGAGACGCGCCAGATCACGTGG	PLCG1	ENSG00000124181	-0.423900179297779	[]	[]	-3	hSpCas9	negative selection	2649556
41159617	41159640	20	+	27260157	HT1080	viability	GAAATTAAGGAGATCCGCCCAGG	PLCG1	ENSG00000124181	0.622170680215921	[]	[]	5	hSpCas9	negative selection	2653145
41159689	41159712	20	-	27260157	HT1080	viability	ACAAAGCAATGTGACTGGTCCGG	PLCG1	ENSG00000124181	0.956368043228469	[]	[]	7	hSpCas9	negative selection	2654218
41137739	41137762	20	-	27260157	HT1080	viability	GGAGTAGAACAAAGTCATGACGG	PLCG1	ENSG00000124181	0.596433321493873	[]	[]	5	hSpCas9	negative selection	2654808
41160127	41160150	20	+	27260157	HT1080	viability	CTCAGTGGATCGGAATCGTGAGG	PLCG1	ENSG00000124181	0.151015562215173	[]	[]	1	hSpCas9	negative selection	2655181
41137700	41137723	20	-	27260157	HT1080	viability	GCGGCAGAGGTGCAGCACCTCGG	PLCG1	ENSG00000124181	0.60328653384689	[]	[]	5	hSpCas9	negative selection	2657230
41137790	41137813	20	-	27260157	HT1080	viability	CGTCTCCAGCTTGACCTGGAAGG	PLCG1	ENSG00000124181	0.868761332903974	[]	[]	7	hSpCas9	negative selection	2659644
41137627	41137650	20	+	27260157	HT1080	viability	CCCAGCGTCGGAGCCATGGCGGG	PLCG1	ENSG00000124181	0.779643941648966	[]	[]	6	hSpCas9	negative selection	2659952
41137659	41137682	20	-	27260157	HT1080	viability	GCCCGCAGCCGTTGGCGCAAGGG	PLCG1	ENSG00000124181	-0.237690477538896	[]	[]	0	hSpCas9	negative selection	2663573
41137725	41137748	20	-	27260157	HT1080	viability	TCATGACGGTGCCCACCTCGAGG	PLCG1	ENSG00000124181	-0.0174239157719094	[]	[]	0	hSpCas9	negative selection	2688911
41159676	41159699	20	-	27260157	HT1080	viability	ACTGGTCCGGCCGGAAAGCTGGG	PLCG1	ENSG00000124181	0.620693040187773	[]	[]	5	hSpCas9	negative selection	2692210
41162467	41162490	20	+	27260157	HT1080	viability	CCTGAAGAACATGCTGTCCCAGG	PLCG1	ENSG00000124181	0.822226591562303	[]	[]	7	hSpCas9	negative selection	2694660
41137719	41137742	20	-	27260157	HT1080	viability	CGGTGCCCACCTCGAGGCTGCGG	PLCG1	ENSG00000124181	-1.01996761012872	[]	[]	-8	hSpCas9	negative selection	2721042
41137710	41137733	20	+	27260157	HT1080	viability	GCACCTCTGCCGCAGCCTCGAGG	PLCG1	ENSG00000124181	0.963163104543408	[]	[]	7	hSpCas9	negative selection	2723322
41137690	41137713	20	-	27260157	HT1080	viability	TGCAGCACCTCGGCGTCCGAGGG	PLCG1	ENSG00000124181	0.1273005012396	[]	[]	1	hSpCas9	negative selection	2724027
41137805	41137828	20	+	27260157	HT1080	viability	TGGAGACGCGCCAGATCACGTGG	PLCG1	ENSG00000124181	0.321301955240946	[]	[]	3	hSpCas9	negative selection	2725686
41159617	41159640	20	+	27260157	MKN45	viability	GAAATTAAGGAGATCCGCCCAGG	PLCG1	ENSG00000124181	0.0737872197074637	[]	[]	0	hSpCas9	negative selection	2729275
41159689	41159712	20	-	27260157	MKN45	viability	ACAAAGCAATGTGACTGGTCCGG	PLCG1	ENSG00000124181	0.212344240372544	[]	[]	5	hSpCas9	negative selection	2730348
41137739	41137762	20	-	27260157	MKN45	viability	GGAGTAGAACAAAGTCATGACGG	PLCG1	ENSG00000124181	0.145767688114868	[]	[]	5	hSpCas9	negative selection	2730938
41160127	41160150	20	+	27260157	MKN45	viability	CTCAGTGGATCGGAATCGTGAGG	PLCG1	ENSG00000124181	-0.858095229216406	[]	[]	-7	hSpCas9	negative selection	2731311
41137700	41137723	20	-	27260157	MKN45	viability	GCGGCAGAGGTGCAGCACCTCGG	PLCG1	ENSG00000124181	-0.341453774457701	[]	[]	-1	hSpCas9	negative selection	2733360
41137790	41137813	20	-	27260157	MKN45	viability	CGTCTCCAGCTTGACCTGGAAGG	PLCG1	ENSG00000124181	0.201851720163353	[]	[]	5	hSpCas9	negative selection	2735774
41137627	41137650	20	+	27260157	MKN45	viability	CCCAGCGTCGGAGCCATGGCGGG	PLCG1	ENSG00000124181	1.10551984900955	[]	[]	8	hSpCas9	negative selection	2736082
41137659	41137682	20	-	27260157	MKN45	viability	GCCCGCAGCCGTTGGCGCAAGGG	PLCG1	ENSG00000124181	-0.330973755568498	[]	[]	-1	hSpCas9	negative selection	2739703
41137725	41137748	20	-	27260157	MKN45	viability	TCATGACGGTGCCCACCTCGAGG	PLCG1	ENSG00000124181	0.334413645872826	[]	[]	6	hSpCas9	negative selection	2765041
41159676	41159699	20	-	27260157	MKN45	viability	ACTGGTCCGGCCGGAAAGCTGGG	PLCG1	ENSG00000124181	0.942487482135772	[]	[]	8	hSpCas9	negative selection	2768340
41162467	41162490	20	+	27260157	MKN45	viability	CCTGAAGAACATGCTGTCCCAGG	PLCG1	ENSG00000124181	0.482170256068132	[]	[]	6	hSpCas9	negative selection	2770790
41137719	41137742	20	-	27260157	MKN45	viability	CGGTGCCCACCTCGAGGCTGCGG	PLCG1	ENSG00000124181	-0.139502261555107	[]	[]	0	hSpCas9	negative selection	2797172
41137710	41137733	20	+	27260157	MKN45	viability	GCACCTCTGCCGCAGCCTCGAGG	PLCG1	ENSG00000124181	-0.0707948949913905	[]	[]	0	hSpCas9	negative selection	2799452
41137690	41137713	20	-	27260157	MKN45	viability	TGCAGCACCTCGGCGTCCGAGGG	PLCG1	ENSG00000124181	0.127990804684136	[]	[]	4	hSpCas9	negative selection	2800157
41137805	41137828	20	+	27260157	MKN45	viability	TGGAGACGCGCCAGATCACGTGG	PLCG1	ENSG00000124181	0.2582680275316	[]	[]	5	hSpCas9	negative selection	2801816
41159617	41159640	20	+	27260157	RKO	viability	GAAATTAAGGAGATCCGCCCAGG	PLCG1	ENSG00000124181	-0.0369770325707689	[]	[]	0	hSpCas9	negative selection	2805405
41159689	41159712	20	-	27260157	RKO	viability	ACAAAGCAATGTGACTGGTCCGG	PLCG1	ENSG00000124181	-8.26829728514666e-05	[]	[]	0	hSpCas9	negative selection	2806478
41137739	41137762	20	-	27260157	RKO	viability	GGAGTAGAACAAAGTCATGACGG	PLCG1	ENSG00000124181	-0.232445711936081	[]	[]	-1	hSpCas9	negative selection	2807068
41160127	41160150	20	+	27260157	RKO	viability	CTCAGTGGATCGGAATCGTGAGG	PLCG1	ENSG00000124181	-0.320240592461214	[]	[]	-6	hSpCas9	negative selection	2807441
41137700	41137723	20	-	27260157	RKO	viability	GCGGCAGAGGTGCAGCACCTCGG	PLCG1	ENSG00000124181	-0.714084128041981	[]	[]	-7	hSpCas9	negative selection	2809490
41137790	41137813	20	-	27260157	RKO	viability	CGTCTCCAGCTTGACCTGGAAGG	PLCG1	ENSG00000124181	-0.52145479385792	[]	[]	-6	hSpCas9	negative selection	2811904
41137627	41137650	20	+	27260157	RKO	viability	CCCAGCGTCGGAGCCATGGCGGG	PLCG1	ENSG00000124181	0.220943893401538	[]	[]	1	hSpCas9	negative selection	2812212
41137659	41137682	20	-	27260157	RKO	viability	GCCCGCAGCCGTTGGCGCAAGGG	PLCG1	ENSG00000124181	0.458852657151337	[]	[]	2	hSpCas9	negative selection	2815833
41137725	41137748	20	-	27260157	RKO	viability	TCATGACGGTGCCCACCTCGAGG	PLCG1	ENSG00000124181	1.34862846621693	[]	[]	9	hSpCas9	negative selection	2841171
41159676	41159699	20	-	27260157	RKO	viability	ACTGGTCCGGCCGGAAAGCTGGG	PLCG1	ENSG00000124181	0.760203320169734	[]	[]	8	hSpCas9	negative selection	2844470
41162467	41162490	20	+	27260157	RKO	viability	CCTGAAGAACATGCTGTCCCAGG	PLCG1	ENSG00000124181	0.847514086057474	[]	[]	8	hSpCas9	negative selection	2846920
41137719	41137742	20	-	27260157	RKO	viability	CGGTGCCCACCTCGAGGCTGCGG	PLCG1	ENSG00000124181	-0.16590476088387	[]	[]	-1	hSpCas9	negative selection	2873302
41137710	41137733	20	+	27260157	RKO	viability	GCACCTCTGCCGCAGCCTCGAGG	PLCG1	ENSG00000124181	-0.890395010777114	[]	[]	-8	hSpCas9	negative selection	2875582
41137690	41137713	20	-	27260157	RKO	viability	TGCAGCACCTCGGCGTCCGAGGG	PLCG1	ENSG00000124181	0.440975403423291	[]	[]	2	hSpCas9	negative selection	2876287
41137805	41137828	20	+	27260157	RKO	viability	TGGAGACGCGCCAGATCACGTGG	PLCG1	ENSG00000124181	-0.670329542393763	[]	[]	-7	hSpCas9	negative selection	2877946
41159617	41159640	20	+	27260157	SF268	viability	GAAATTAAGGAGATCCGCCCAGG	PLCG1	ENSG00000124181	0.662286679090205	[]	[]	8	hSpCas9	negative selection	2881535
41159689	41159712	20	-	27260157	SF268	viability	ACAAAGCAATGTGACTGGTCCGG	PLCG1	ENSG00000124181	1.29027195140453	[]	[]	9	hSpCas9	negative selection	2882608
41137739	41137762	20	-	27260157	SF268	viability	GGAGTAGAACAAAGTCATGACGG	PLCG1	ENSG00000124181	0.233345301064832	[]	[]	3	hSpCas9	negative selection	2883198
41160127	41160150	20	+	27260157	SF268	viability	CTCAGTGGATCGGAATCGTGAGG	PLCG1	ENSG00000124181	0.514510224816799	[]	[]	7	hSpCas9	negative selection	2883571
41137700	41137723	20	-	27260157	SF268	viability	GCGGCAGAGGTGCAGCACCTCGG	PLCG1	ENSG00000124181	0.573665605125682	[]	[]	8	hSpCas9	negative selection	2885620
41137790	41137813	20	-	27260157	SF268	viability	CGTCTCCAGCTTGACCTGGAAGG	PLCG1	ENSG00000124181	2.22793726074382	[]	[]	9	hSpCas9	negative selection	2888034
41137627	41137650	20	+	27260157	SF268	viability	CCCAGCGTCGGAGCCATGGCGGG	PLCG1	ENSG00000124181	0.525933365094196	[]	[]	8	hSpCas9	negative selection	2888342
41137659	41137682	20	-	27260157	SF268	viability	GCCCGCAGCCGTTGGCGCAAGGG	PLCG1	ENSG00000124181	1.0189826859714	[]	[]	9	hSpCas9	negative selection	2891963
41137725	41137748	20	-	27260157	SF268	viability	TCATGACGGTGCCCACCTCGAGG	PLCG1	ENSG00000124181	-1.08513745008347	[]	[]	-7	hSpCas9	negative selection	2917301
41159676	41159699	20	-	27260157	SF268	viability	ACTGGTCCGGCCGGAAAGCTGGG	PLCG1	ENSG00000124181	0.982638441014318	[]	[]	9	hSpCas9	negative selection	2920600
41162467	41162490	20	+	27260157	SF268	viability	CCTGAAGAACATGCTGTCCCAGG	PLCG1	ENSG00000124181	0.787718040049163	[]	[]	8	hSpCas9	negative selection	2923050
41137719	41137742	20	-	27260157	SF268	viability	CGGTGCCCACCTCGAGGCTGCGG	PLCG1	ENSG00000124181	0.540615126949291	[]	[]	8	hSpCas9	negative selection	2949432
41137710	41137733	20	+	27260157	SF268	viability	GCACCTCTGCCGCAGCCTCGAGG	PLCG1	ENSG00000124181	0.697441829882333	[]	[]	8	hSpCas9	negative selection	2951712
41137690	41137713	20	-	27260157	SF268	viability	TGCAGCACCTCGGCGTCCGAGGG	PLCG1	ENSG00000124181	-0.0941897982977903	[]	[]	0	hSpCas9	negative selection	2952417
41137805	41137828	20	+	27260157	SF268	viability	TGGAGACGCGCCAGATCACGTGG	PLCG1	ENSG00000124181	0.421087739082966	[]	[]	4	hSpCas9	negative selection	2954076
41137764	41137787	20	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	AGAAGTCGCAGCGACCCGAGCGG	PLCG1	ENSG00000124181	-0.9157496294079421	[4,4]	[2,0]	-9	hSpCas9	positive selection	3011800
41159671	41159694	20	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	AGAGGACCCAGCTTTCCGGCCGG	PLCG1	ENSG00000124181	0.25708376585811715	[3,3]	[3,3]	5	hSpCas9	positive selection	3011801
41159645	41159668	20	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	ATAGCGATCAAAGTCCCGTGAGG	PLCG1	ENSG00000124181	-0.19046428662892878	[4,4]	[4,2]	-3	hSpCas9	positive selection	3011802
41163255	41163278	20	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GTTCCTTCTTGACTACCAGGGGG	PLCG1	ENSG00000124181	-0.06824083134878264	[3,3]	[3,2]	-1	hSpCas9	positive selection	3011803
41137764	41137787	20	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	AGAAGTCGCAGCGACCCGAGCGG	PLCG1	ENSG00000124181	0.24194354099930634	[4,4]	[3,3]	4	hSpCas9	positive selection	3079658
41159671	41159694	20	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	AGAGGACCCAGCTTTCCGGCCGG	PLCG1	ENSG00000124181	0.12033197795335354	[3,3]	[4,1]	2	hSpCas9	positive selection	3079659
41159645	41159668	20	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	ATAGCGATCAAAGTCCCGTGAGG	PLCG1	ENSG00000124181	0.8703806129381395	[4,4]	[4,7]	9	hSpCas9	positive selection	3079660
41163255	41163278	20	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GTTCCTTCTTGACTACCAGGGGG	PLCG1	ENSG00000124181	-0.014847235171499579	[3,3]	[4,1]	0	hSpCas9	positive selection	3079661
41159737	41159760		+	24336571	A375	resistance to PLX after 7 days	CTGAAAACGCTGAGCCTGCAAGG	PLCG1	ENSG00000124181	-0.15496499735911173	[15,10]	[11,11]	-5	hSpCas9	positive selection	3136071
41159870	41159893		-	24336571	A375	resistance to PLX after 7 days	GTTCACTTCATCCTCAGATGTGG	PLCG1	ENSG00000124181	0.6812450239844381	[39,37]	[61,62]	9	hSpCas9	positive selection	3136072
41159949	41159972		-	24336571	A375	resistance to PLX after 7 days	GTTCTTACCTCTCAATCTGCAGG	PLCG1	ENSG00000124181	-0.1404941783032503	[12,11]	[12,8]	-4	hSpCas9	positive selection	3136073
41159737	41159760		+	24336571	A375	resistance to PLX after 14 days	CTGAAAACGCTGAGCCTGCAAGG	PLCG1	ENSG00000124181	1.081424984379232	[10,8]	[8,10]	8	hSpCas9	positive selection	3193864
41159870	41159893		-	24336571	A375	resistance to PLX after 14 days	GTTCACTTCATCCTCAGATGTGG	PLCG1	ENSG00000124181	1.9550867132006202	[35,32]	[58,66]	9	hSpCas9	positive selection	3193865
41159949	41159972		-	24336571	A375	resistance to PLX after 14 days	GTTCTTACCTCTCAATCTGCAGG	PLCG1	ENSG00000124181	-0.5647984963933499	[10,11]	[2,3]	-6	hSpCas9	positive selection	3193866
41159737	41159760		+	24336571	A375	viability after 7 days	CTGAAAACGCTGAGCCTGCAAGG	PLCG1	ENSG00000124181	0.4340518532303113	[9]	[15,10]	6	hSpCas9	negative selection	3251657
41159870	41159893		-	24336571	A375	viability after 7 days	GTTCACTTCATCCTCAGATGTGG	PLCG1	ENSG00000124181	-0.22337314727961988	[47]	[39,37]	-3	hSpCas9	negative selection	3251658
41159949	41159972		-	24336571	A375	viability after 7 days	GTTCTTACCTCTCAATCTGCAGG	PLCG1	ENSG00000124181	-1.1539375851896458	[29]	[12,11]	-9	hSpCas9	negative selection	3251659
41159737	41159760		+	24336571	A375	viability after 14 days	CTGAAAACGCTGAGCCTGCAAGG	PLCG1	ENSG00000124181	0.0619295351656598	[9]	[10,8]	0	hSpCas9	negative selection	3309450
41159870	41159893		-	24336571	A375	viability after 14 days	GTTCACTTCATCCTCAGATGTGG	PLCG1	ENSG00000124181	-0.3812866884368922	[47]	[35,32]	-4	hSpCas9	negative selection	3309451
41159949	41159972		-	24336571	A375	viability after 14 days	GTTCTTACCTCTCAATCTGCAGG	PLCG1	ENSG00000124181	-1.2477816944704687	[29]	[10,11]	-9	hSpCas9	negative selection	3309452
41160112	41160135	20	-	27383988	293T	resistance to West Nile virus (flavivirus)	CCACTGAGTAAAACTGCTTCCGG	PLCG1	ENSG00000124181	5.823095146933681	[226,226]	[83,83]	9	hSpCas9	positive selection	3386213
41159604	41159627	20	+	27383988	293T	resistance to West Nile virus (flavivirus)	AGTTGACATTCGTGAAATTAAGG	PLCG1	ENSG00000124181	-0.819489385604996	[269,269]	[0,0]	-5	hSpCas9	positive selection	3386214
41159870	41159893	20	-	27383988	293T	resistance to West Nile virus (flavivirus)	GTTCACTTCATCCTCAGATGTGG	PLCG1	ENSG00000124181	3.0924192847701475	[286,286]	[15,15]	8	hSpCas9	positive selection	3386215
41137763	41137786	20	+	26780180	HT29	viability (Avana library 4 designs)	AGAAGTCGCAGCGACCCGAGCGG	PLCG1	ENSG00000124181	0.0623928972314548	[]	[]	0	hSpCas9	negative selection	3449891
41159670	41159693	20	+	26780180	HT29	viability (Avana library 4 designs)	AGAGGACCCAGCTTTCCGGCCGG	PLCG1	ENSG00000124181	1.03449807844457	[]	[]	4	hSpCas9	negative selection	3449892
41159645	41159668	20	-	26780180	HT29	viability (Avana library 4 designs)	ATAGCGATCAAAGTCCCGTGAGG	PLCG1	ENSG00000124181	-0.389746848973068	[]	[]	-6	hSpCas9	negative selection	3449893
41163254	41163277	20	+	26780180	HT29	viability (Avana library 4 designs)	GTTCCTTCTTGACTACCAGGGGG	PLCG1	ENSG00000124181	0.896506340263494	[]	[]	3	hSpCas9	negative selection	3449894
41163254	41163277	20	+	26780180	A375	viability (Avana lentiCRISPRv2)	GTTCCTTCTTGACTACCAGGGGG	PLCG1	ENSG00000124181	-3.9680418084526	[]	[]	-4	hSpCas9	negative selection	3544872
41137763	41137786	20	+	26780180	A375	viability (Avana lentiCRISPRv2)	AGAAGTCGCAGCGACCCGAGCGG	PLCG1	ENSG00000124181	2.63515911124901	[]	[]	4	hSpCas9	negative selection	3544873
41159645	41159668	20	-	26780180	A375	viability (Avana lentiCRISPRv2)	ATAGCGATCAAAGTCCCGTGAGG	PLCG1	ENSG00000124181	2.4554663910463	[]	[]	3	hSpCas9	negative selection	3544874
41159670	41159693	20	+	26780180	A375	viability (Avana lentiCRISPRv2)	AGAGGACCCAGCTTTCCGGCCGG	PLCG1	ENSG00000124181	-0.0561802843363771	[]	[]	0	hSpCas9	negative selection	3544875
41163428	41163451	20	-	26780180	A375	viability (Avana lentiCRISPRv2)	TCTCTCGTAAGGGGTCTCGGAGG	PLCG1	ENSG00000124181	-2.51164796088348	[]	[]	-3	hSpCas9	negative selection	3544876
41159652	41159675	20	+	26780180	A375	viability (Avana lentiCRISPRv2)	GGACTTTGATCGCTATCAAGAGG	PLCG1	ENSG00000124181	-8.09729980655858	[]	[]	-7	hSpCas9	negative selection	3544877
41163254	41163277	20	+	26780180	A375	viability (Avana lentiGuide)	GTTCCTTCTTGACTACCAGGGGG	PLCG1	ENSG00000124181	-0.338903019624347	[]	[]	0	hSpCas9	negative selection	3653531
41137763	41137786	20	+	26780180	A375	viability (Avana lentiGuide)	AGAAGTCGCAGCGACCCGAGCGG	PLCG1	ENSG00000124181	4.56841132482326	[]	[]	4	hSpCas9	negative selection	3653532
41159645	41159668	20	-	26780180	A375	viability (Avana lentiGuide)	ATAGCGATCAAAGTCCCGTGAGG	PLCG1	ENSG00000124181	-0.0927878054321978	[]	[]	0	hSpCas9	negative selection	3653533
41159670	41159693	20	+	26780180	A375	viability (Avana lentiGuide)	AGAGGACCCAGCTTTCCGGCCGG	PLCG1	ENSG00000124181	5.62181993563454	[]	[]	5	hSpCas9	negative selection	3653534
41163428	41163451	20	-	26780180	A375	viability (Avana lentiGuide)	TCTCTCGTAAGGGGTCTCGGAGG	PLCG1	ENSG00000124181	5.43826444041282	[]	[]	5	hSpCas9	negative selection	3653535
41159652	41159675	20	+	26780180	A375	viability (Avana lentiGuide)	GGACTTTGATCGCTATCAAGAGG	PLCG1	ENSG00000124181	2.15810408723426	[]	[]	2	hSpCas9	negative selection	3653536
41163254	41163277	20	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GTTCCTTCTTGACTACCAGGGGG	PLCG1	ENSG00000124181	-0.009305539787732707	[4]	[5,4]	0	hSpCas9	positive selection	3762190
41137763	41137786	20	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AGAAGTCGCAGCGACCCGAGCGG	PLCG1	ENSG00000124181	0.2939631328765595	[5]	[7,6]	8	hSpCas9	positive selection	3762191
41159645	41159668	20	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ATAGCGATCAAAGTCCCGTGAGG	PLCG1	ENSG00000124181	0.392690751082032	[5]	[7,7]	9	hSpCas9	positive selection	3762192
41159670	41159693	20	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AGAGGACCCAGCTTTCCGGCCGG	PLCG1	ENSG00000124181	0.22175931272489846	[5]	[5,6]	6	hSpCas9	positive selection	3762193
41163428	41163451	20	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TCTCTCGTAAGGGGTCTCGGAGG	PLCG1	ENSG00000124181	-0.3870396672644949	[0]	[0,0]	-5	hSpCas9	positive selection	3762194
41159652	41159675	20	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGACTTTGATCGCTATCAAGAGG	PLCG1	ENSG00000124181	-0.5061924518435905	[5]	[3,2]	-6	hSpCas9	positive selection	3762195
41163254	41163277	20	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GTTCCTTCTTGACTACCAGGGGG	PLCG1	ENSG00000124181	0.297065962864001	[5]	[4,6]	8	hSpCas9	positive selection	3870797
41137763	41137786	20	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AGAAGTCGCAGCGACCCGAGCGG	PLCG1	ENSG00000124181	-0.36494634561613293	[6]	[4,3]	-5	hSpCas9	positive selection	3870798
41159645	41159668	20	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ATAGCGATCAAAGTCCCGTGAGG	PLCG1	ENSG00000124181	0.3307397828074894	[6]	[6,6]	8	hSpCas9	positive selection	3870799
41159670	41159693	20	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AGAGGACCCAGCTTTCCGGCCGG	PLCG1	ENSG00000124181	0.30429876723055355	[5]	[6,5]	8	hSpCas9	positive selection	3870800
41163428	41163451	20	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TCTCTCGTAAGGGGTCTCGGAGG	PLCG1	ENSG00000124181	-0.09883997356766816	[0]	[0,0]	-1	hSpCas9	positive selection	3870801
41159652	41159675	20	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGACTTTGATCGCTATCAAGAGG	PLCG1	ENSG00000124181	0.050547605379381924	[5]	[4,4]	1	hSpCas9	positive selection	3870802
41159604	41159627	20	+	26780180	A375	viability	AGTTGACATTCGTGAAATTAAGG	PLCG1	ENSG00000124181	0.696701588953678	[]	[]	2	hSpCas9	negative selection	3981622
41159645	41159668	20	-	26780180	A375	viability	ATAGCGATCAAAGTCCCGTGAGG	PLCG1	ENSG00000124181	1.62027126011793	[]	[]	8	hSpCas9	negative selection	3981623
41160112	41160135	20	-	26780180	A375	viability	CCACTGAGTAAAACTGCTTCCGG	PLCG1	ENSG00000124181	1.29017198984178	[]	[]	7	hSpCas9	negative selection	3981624
41159916	41159939	20	+	26780180	A375	viability	GCTGATGGAGGATACATTGCAGG	PLCG1	ENSG00000124181	1.31956460750002	[]	[]	7	hSpCas9	negative selection	3981625
41159870	41159893	20	-	26780180	A375	viability	GTTCACTTCATCCTCAGATGTGG	PLCG1	ENSG00000124181	1.15815721951329	[]	[]	6	hSpCas9	negative selection	3981626
41159949	41159972	20	-	26780180	A375	viability	GTTCTTACCTCTCAATCTGCAGG	PLCG1	ENSG00000124181	0.574105221874707	[]	[]	1	hSpCas9	negative selection	3981627
41159604	41159627	20	+	26780180	HT29	viability (GeCKOv2 library)	AGTTGACATTCGTGAAATTAAGG	PLCG1	ENSG00000124181	0.818495331075171	[]	[]	3	hSpCas9	negative selection	4089588
41159645	41159668	20	-	26780180	HT29	viability (GeCKOv2 library)	ATAGCGATCAAAGTCCCGTGAGG	PLCG1	ENSG00000124181	0.82936216653703	[]	[]	3	hSpCas9	negative selection	4089589
41160112	41160135	20	-	26780180	HT29	viability (GeCKOv2 library)	CCACTGAGTAAAACTGCTTCCGG	PLCG1	ENSG00000124181	0.629882865029592	[]	[]	2	hSpCas9	negative selection	4089590
41159916	41159939	20	+	26780180	HT29	viability (GeCKOv2 library)	GCTGATGGAGGATACATTGCAGG	PLCG1	ENSG00000124181	1.25447725065131	[]	[]	6	hSpCas9	negative selection	4089591
41159870	41159893	20	-	26780180	HT29	viability (GeCKOv2 library)	GTTCACTTCATCCTCAGATGTGG	PLCG1	ENSG00000124181	0.698255420838987	[]	[]	2	hSpCas9	negative selection	4089592
41159949	41159972	20	-	26780180	HT29	viability (GeCKOv2 library)	GTTCTTACCTCTCAATCTGCAGG	PLCG1	ENSG00000124181	0.472811307903024	[]	[]	1	hSpCas9	negative selection	4089593
41159737	41159760	20	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CTGAAAACGCTGAGCCTGCAAGG	PLCG1	ENSG00000124181	0.052389580154029086	[3]	[2,3]	1	hSpCas9	positive selection	4161065
41159870	41159893	20	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GTTCACTTCATCCTCAGATGTGG	PLCG1	ENSG00000124181	0.5234113590111829	[5]	[5,5]	9	hSpCas9	positive selection	4161066
41159949	41159972	20	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GTTCTTACCTCTCAATCTGCAGG	PLCG1	ENSG00000124181	-0.16734327890921155	[3]	[2,1]	-4	hSpCas9	positive selection	4161067
41159737	41159760	20	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CTGAAAACGCTGAGCCTGCAAGG	PLCG1	ENSG00000124181	-0.5779257581090629	[4]	[0,3,0,0]	-7	hSpCas9	positive selection	4225087
41159870	41159893	20	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GTTCACTTCATCCTCAGATGTGG	PLCG1	ENSG00000124181	1.0574433556133869	[5]	[6,6,2,4]	7	hSpCas9	positive selection	4225088
41159949	41159972	20	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GTTCTTACCTCTCAATCTGCAGG	PLCG1	ENSG00000124181	1.4490051508110706	[3]	[4,4,3,3]	9	hSpCas9	positive selection	4225089
41159645	41159668	20	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ATAGCGATCAAAGTCCCGTGAGG	PLCG1	ENSG00000124181	0.48896690712253726	[2]	[4,2]	8	hSpCas9	positive selection	4290651
41159949	41159972	20	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GTTCTTACCTCTCAATCTGCAGG	PLCG1	ENSG00000124181	0.45610867908187147	[3]	[3,3]	8	hSpCas9	positive selection	4290652
41159916	41159939	20	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GCTGATGGAGGATACATTGCAGG	PLCG1	ENSG00000124181	0.010036669851506301	[3]	[3,1]	0	hSpCas9	positive selection	4290653
41160112	41160135	20	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCACTGAGTAAAACTGCTTCCGG	PLCG1	ENSG00000124181	0.3937864501329366	[3]	[4,2]	7	hSpCas9	positive selection	4354903
41159604	41159627	20	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AGTTGACATTCGTGAAATTAAGG	PLCG1	ENSG00000124181	0.2583325173256619	[3]	[3,2]	5	hSpCas9	positive selection	4354904
41159870	41159893	20	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GTTCACTTCATCCTCAGATGTGG	PLCG1	ENSG00000124181	0.22365940733774117	[2]	[3,1]	4	hSpCas9	positive selection	4354905
41137832	41137854	20	+	27760321	OCIAML3	viability	GGGGCGCCGACAAGATCGAGGG	PLCG1	ENSG00000124181	0.32139164792423863	[492,441]	[408,517]	4	hSpCas9	negative selection	4428393
41159645	41159667	20	-	27760321	OCIAML3	viability	TAGCGATCAAAGTCCCGTGAGG	PLCG1	ENSG00000124181	0.31599983400802956	[582,532]	[549,533]	3	hSpCas9	negative selection	4428394
41163913	41163935	20	+	27760321	OCIAML3	viability	CTATCCAGGTACCTGACCGGGG	PLCG1	ENSG00000124181	0.1898826922145867	[630,519]	[362,703]	2	hSpCas9	negative selection	4428395
41165038	41165060	20	+	27760321	OCIAML3	viability	CGTGGAGATCTCTGCCGACGGG	PLCG1	ENSG00000124181	0.2381193815815334	[661,533]	[558,534]	2	hSpCas9	negative selection	4428396
41163438	41163460	20	-	27760321	OCIAML3	viability	GCTCCTCGATCTCTCGTAAGGG	PLCG1	ENSG00000124181	0.979994897307016	[346,302]	[471,536]	9	hSpCas9	negative selection	4428397
41137832	41137854	20	+	27760321	OCIAML2	viability	GGGGCGCCGACAAGATCGAGGG	PLCG1	ENSG00000124181	0.18849221542219186	[492,441]	[404,463]	2	hSpCas9	negative selection	4511856
41159645	41159667	20	-	27760321	OCIAML2	viability	TAGCGATCAAAGTCCCGTGAGG	PLCG1	ENSG00000124181	0.4425914746329821	[582,532]	[516,739]	6	hSpCas9	negative selection	4511857
41163913	41163935	20	+	27760321	OCIAML2	viability	CTATCCAGGTACCTGACCGGGG	PLCG1	ENSG00000124181	0.49154371273147296	[630,519]	[575,750]	6	hSpCas9	negative selection	4511858
41165038	41165060	20	+	27760321	OCIAML2	viability	CGTGGAGATCTCTGCCGACGGG	PLCG1	ENSG00000124181	0.0033216169743112145	[661,533]	[451,521]	0	hSpCas9	negative selection	4511859
41163438	41163460	20	-	27760321	OCIAML2	viability	GCTCCTCGATCTCTCGTAAGGG	PLCG1	ENSG00000124181	0.5902468871848578	[346,302]	[302,515]	7	hSpCas9	negative selection	4511860
41137832	41137854	20	+	27760321	MV411	viability	GGGGCGCCGACAAGATCGAGGG	PLCG1	ENSG00000124181	0.23960423776724904	[492,441]	[370,352]	1	hSpCas9	negative selection	4595319
41159645	41159667	20	-	27760321	MV411	viability	TAGCGATCAAAGTCCCGTGAGG	PLCG1	ENSG00000124181	0.7772044310909492	[582,532]	[892,236]	6	hSpCas9	negative selection	4595320
41163913	41163935	20	+	27760321	MV411	viability	CTATCCAGGTACCTGACCGGGG	PLCG1	ENSG00000124181	0.41966263201009796	[630,519]	[308,800]	3	hSpCas9	negative selection	4595321
41165038	41165060	20	+	27760321	MV411	viability	CGTGGAGATCTCTGCCGACGGG	PLCG1	ENSG00000124181	0.8546634399482322	[661,533]	[566,923]	6	hSpCas9	negative selection	4595322
41163438	41163460	20	-	27760321	MV411	viability	GCTCCTCGATCTCTCGTAAGGG	PLCG1	ENSG00000124181	0.10175022944397238	[346,302]	[249,198]	0	hSpCas9	negative selection	4595323
41137832	41137854	20	+	27760321	HL60	viability	GGGGCGCCGACAAGATCGAGGG	PLCG1	ENSG00000124181	-0.3413708702532298	[492,441]	[269,333]	-4	hSpCas9	negative selection	4678782
41159645	41159667	20	-	27760321	HL60	viability	TAGCGATCAAAGTCCCGTGAGG	PLCG1	ENSG00000124181	0.12203768261531228	[582,532]	[457,535]	1	hSpCas9	negative selection	4678783
41163913	41163935	20	+	27760321	HL60	viability	CTATCCAGGTACCTGACCGGGG	PLCG1	ENSG00000124181	0.4010535861078081	[630,519]	[630,603]	5	hSpCas9	negative selection	4678784
41165038	41165060	20	+	27760321	HL60	viability	CGTGGAGATCTCTGCCGACGGG	PLCG1	ENSG00000124181	0.3744269688988476	[661,533]	[654,602]	4	hSpCas9	negative selection	4678785
41163438	41163460	20	-	27760321	HL60	viability	GCTCCTCGATCTCTCGTAAGGG	PLCG1	ENSG00000124181	0.5503187991430262	[346,302]	[400,373]	6	hSpCas9	negative selection	4678786
41137832	41137854	20	+	27760321	HT1080	viability	GGGGCGCCGACAAGATCGAGGG	PLCG1	ENSG00000124181	2.537123047076475	[441,344]	[1623,127]	9	hSpCas9	negative selection	4762245
41159645	41159667	20	-	27760321	HT1080	viability	TAGCGATCAAAGTCCCGTGAGG	PLCG1	ENSG00000124181	0.8854683866542038	[532,415]	[226,482]	5	hSpCas9	negative selection	4762246
41163913	41163935	20	+	27760321	HT1080	viability	CTATCCAGGTACCTGACCGGGG	PLCG1	ENSG00000124181	0.05630446801942829	[519,405]	[218,161]	0	hSpCas9	negative selection	4762247
41165038	41165060	20	+	27760321	HT1080	viability	CGTGGAGATCTCTGCCGACGGG	PLCG1	ENSG00000124181	0.6136639553230758	[533,416]	[191,396]	3	hSpCas9	negative selection	4762248
41163438	41163460	20	-	27760321	HT1080	viability	GCTCCTCGATCTCTCGTAAGGG	PLCG1	ENSG00000124181	2.297891377595634	[302,236]	[612,436]	9	hSpCas9	negative selection	4762249
41137832	41137854	20	+	27760321	HT29	viability after 7 days	GGGGCGCCGACAAGATCGAGGG	PLCG1	ENSG00000124181	0.39192865499528395	[441,344]	[1061,563,428]	6	hSpCas9	negative selection	4845708
41159645	41159667	20	-	27760321	HT29	viability after 7 days	TAGCGATCAAAGTCCCGTGAGG	PLCG1	ENSG00000124181	-0.04013380459236915	[532,415]	[616,523,639]	0	hSpCas9	negative selection	4845709
41163913	41163935	20	+	27760321	HT29	viability after 7 days	CTATCCAGGTACCTGACCGGGG	PLCG1	ENSG00000124181	0.562187450392662	[519,405]	[924,768,945]	8	hSpCas9	negative selection	4845710
41165038	41165060	20	+	27760321	HT29	viability after 7 days	CGTGGAGATCTCTGCCGACGGG	PLCG1	ENSG00000124181	0.13629024430622744	[533,416]	[757,687,583]	2	hSpCas9	negative selection	4845711
41163438	41163460	20	-	27760321	HT29	viability after 7 days	GCTCCTCGATCTCTCGTAAGGG	PLCG1	ENSG00000124181	0.45007352574894444	[302,236]	[425,472,514]	7	hSpCas9	negative selection	4845712
41137832	41137854	20	+	27760321	HT29	viability after 25 days	GGGGCGCCGACAAGATCGAGGG	PLCG1	ENSG00000124181	0.9123067476083485	[441,344]	[613,983,966]	9	hSpCas9	negative selection	4929171
41159645	41159667	20	-	27760321	HT29	viability after 25 days	TAGCGATCAAAGTCCCGTGAGG	PLCG1	ENSG00000124181	0.558820586986568	[532,415]	[585,959,869]	6	hSpCas9	negative selection	4929172
41163913	41163935	20	+	27760321	HT29	viability after 25 days	CTATCCAGGTACCTGACCGGGG	PLCG1	ENSG00000124181	1.0856292904276605	[519,405]	[1131,1160,1067]	9	hSpCas9	negative selection	4929173
41165038	41165060	20	+	27760321	HT29	viability after 25 days	CGTGGAGATCTCTGCCGACGGG	PLCG1	ENSG00000124181	0.6320761047530656	[533,416]	[933,842,730]	7	hSpCas9	negative selection	4929174
41163438	41163460	20	-	27760321	HT29	viability after 25 days	GCTCCTCGATCTCTCGTAAGGG	PLCG1	ENSG00000124181	1.177552740995606	[302,236]	[748,451,910]	9	hSpCas9	negative selection	4929175
41137832	41137854	20	+	27760321	HT29	viability after 22 days	GGGGCGCCGACAAGATCGAGGG	PLCG1	ENSG00000124181	1.0041357063683263	[441,344]	[1089,776,864]	9	hSpCas9	negative selection	5012634
41159645	41159667	20	-	27760321	HT29	viability after 22 days	TAGCGATCAAAGTCCCGTGAGG	PLCG1	ENSG00000124181	0.5496341346557596	[532,415]	[525,898,992]	6	hSpCas9	negative selection	5012635
41163913	41163935	20	+	27760321	HT29	viability after 22 days	CTATCCAGGTACCTGACCGGGG	PLCG1	ENSG00000124181	0.8057000770324207	[519,405]	[977,1072,752]	8	hSpCas9	negative selection	5012636
41165038	41165060	20	+	27760321	HT29	viability after 22 days	CGTGGAGATCTCTGCCGACGGG	PLCG1	ENSG00000124181	0.5415341206147524	[533,416]	[815,984,596]	6	hSpCas9	negative selection	5012637
41163438	41163460	20	-	27760321	HT29	viability after 22 days	GCTCCTCGATCTCTCGTAAGGG	PLCG1	ENSG00000124181	1.3832989771817354	[302,236]	[803,543,1097]	9	hSpCas9	negative selection	5012638
41137832	41137854	20	+	27760321	HT29	viability after 19 days	GGGGCGCCGACAAGATCGAGGG	PLCG1	ENSG00000124181	1.4968405668365534	[441,344]	[811,1396,1541]	9	hSpCas9	negative selection	5096097
41159645	41159667	20	-	27760321	HT29	viability after 19 days	TAGCGATCAAAGTCCCGTGAGG	PLCG1	ENSG00000124181	0.6922353961002986	[532,415]	[1021,688,931]	7	hSpCas9	negative selection	5096098
41163913	41163935	20	+	27760321	HT29	viability after 19 days	CTATCCAGGTACCTGACCGGGG	PLCG1	ENSG00000124181	1.1634924405459641	[519,405]	[1116,994,1428]	9	hSpCas9	negative selection	5096099
41165038	41165060	20	+	27760321	HT29	viability after 19 days	CGTGGAGATCTCTGCCGACGGG	PLCG1	ENSG00000124181	0.5882836676099243	[533,416]	[777,1007,667]	6	hSpCas9	negative selection	5096100
41163438	41163460	20	-	27760321	HT29	viability after 19 days	GCTCCTCGATCTCTCGTAAGGG	PLCG1	ENSG00000124181	0.7256056405745097	[302,236]	[445,408,663]	7	hSpCas9	negative selection	5096101
41137832	41137854	20	+	27760321	HT29	viability after 16 days	GGGGCGCCGACAAGATCGAGGG	PLCG1	ENSG00000124181	0.6707757110549232	[441,344]	[793,709,606]	7	hSpCas9	negative selection	5179560
41159645	41159667	20	-	27760321	HT29	viability after 16 days	TAGCGATCAAAGTCCCGTGAGG	PLCG1	ENSG00000124181	0.28993138348469805	[532,415]	[535,967,423]	3	hSpCas9	negative selection	5179561
41163913	41163935	20	+	27760321	HT29	viability after 16 days	CTATCCAGGTACCTGACCGGGG	PLCG1	ENSG00000124181	0.8431488794338435	[519,405]	[868,1046,862]	8	hSpCas9	negative selection	5179562
41165038	41165060	20	+	27760321	HT29	viability after 16 days	CGTGGAGATCTCTGCCGACGGG	PLCG1	ENSG00000124181	0.8039288393120418	[533,416]	[1067,791,942]	8	hSpCas9	negative selection	5179563
41163438	41163460	20	-	27760321	HT29	viability after 16 days	GCTCCTCGATCTCTCGTAAGGG	PLCG1	ENSG00000124181	0.7294896603346228	[302,236]	[278,375,829]	8	hSpCas9	negative selection	5179564
41137832	41137854	20	+	27760321	HT29	viability after 13 days	GGGGCGCCGACAAGATCGAGGG	PLCG1	ENSG00000124181	0.4350069824337167	[441,344]	[438,577,821]	5	hSpCas9	negative selection	5263023
41159645	41159667	20	-	27760321	HT29	viability after 13 days	TAGCGATCAAAGTCCCGTGAGG	PLCG1	ENSG00000124181	0.3873289333202248	[532,415]	[638,731,784]	5	hSpCas9	negative selection	5263024
41163913	41163935	20	+	27760321	HT29	viability after 13 days	CTATCCAGGTACCTGACCGGGG	PLCG1	ENSG00000124181	0.718134916922722	[519,405]	[1045,697,904]	8	hSpCas9	negative selection	5263025
41165038	41165060	20	+	27760321	HT29	viability after 13 days	CGTGGAGATCTCTGCCGACGGG	PLCG1	ENSG00000124181	0.44999520436851587	[533,416]	[924,714,627]	6	hSpCas9	negative selection	5263026
41163438	41163460	20	-	27760321	HT29	viability after 13 days	GCTCCTCGATCTCTCGTAAGGG	PLCG1	ENSG00000124181	0.4236152089068616	[302,236]	[311,481,463]	5	hSpCas9	negative selection	5263027
41137832	41137854	20	+	27760321	HT29	viability after 10 days	GGGGCGCCGACAAGATCGAGGG	PLCG1	ENSG00000124181	-0.048826359995854426	[441,344]	[530,513,382]	0	hSpCas9	negative selection	5346486
41159645	41159667	20	-	27760321	HT29	viability after 10 days	TAGCGATCAAAGTCCCGTGAGG	PLCG1	ENSG00000124181	0.5568236950736665	[532,415]	[825,904,883]	7	hSpCas9	negative selection	5346487
41163913	41163935	20	+	27760321	HT29	viability after 10 days	CTATCCAGGTACCTGACCGGGG	PLCG1	ENSG00000124181	0.42877796479738306	[519,405]	[799,860,677]	6	hSpCas9	negative selection	5346488
41165038	41165060	20	+	27760321	HT29	viability after 10 days	CGTGGAGATCTCTGCCGACGGG	PLCG1	ENSG00000124181	0.44706871567951373	[533,416]	[805,1010,620]	6	hSpCas9	negative selection	5346489
41163438	41163460	20	-	27760321	HT29	viability after 10 days	GCTCCTCGATCTCTCGTAAGGG	PLCG1	ENSG00000124181	0.7968816418341711	[302,236]	[598,355,790]	9	hSpCas9	negative selection	5346490
41137832	41137854	20	+	27760321	MOLM13	viability	GGGGCGCCGACAAGATCGAGGG	PLCG1	ENSG00000124181	-1.3695355753562848	[492,441]	[41,152]	-7	hSpCas9	negative selection	5429949
41159645	41159667	20	-	27760321	MOLM13	viability	TAGCGATCAAAGTCCCGTGAGG	PLCG1	ENSG00000124181	-0.16123840502028824	[582,532]	[416,165]	-1	hSpCas9	negative selection	5429950
41163913	41163935	20	+	27760321	MOLM13	viability	CTATCCAGGTACCTGACCGGGG	PLCG1	ENSG00000124181	-0.3016215746269584	[630,519]	[339,195]	-2	hSpCas9	negative selection	5429951
41165038	41165060	20	+	27760321	MOLM13	viability	CGTGGAGATCTCTGCCGACGGG	PLCG1	ENSG00000124181	0.05877450976617127	[661,533]	[268,417]	0	hSpCas9	negative selection	5429952
41163438	41163460	20	-	27760321	MOLM13	viability	GCTCCTCGATCTCTCGTAAGGG	PLCG1	ENSG00000124181	0.7485520269791814	[346,302]	[140,448]	5	hSpCas9	negative selection	5429953
41137833	41137856	20	+	27661255	K562	viability	GGGCGCCGACAAGATCGAGGGGG	PLCG1	ENSG00000124181	0.2101341914822984	[1139,1423]	[1275,1097]	7	dCas9-KRAB	negative selection	5502386
41137527	41137550	20	-	27661255	K562	viability	GGCAGACGAGCGGGACCCGGCGG	PLCG1	ENSG00000124181	-0.3263965748552295	[721,756]	[467,472]	-7	dCas9-KRAB	negative selection	5502387
41137595	41137618	20	-	27661255	K562	viability	GGCACAGGCCAGGACCGCCCGGG	PLCG1	ENSG00000124181	-0.07633878467202301	[792,783]	[691,516]	-3	dCas9-KRAB	negative selection	5502388
41159645	41159668	20	-	27260156	BXPC3	viability	ATAGCGATCAAAGTCCCGTGAGG	PLCG1	ENSG00000124181	-0.1913630025082056	[382]	[326,372,363,335]	-4	hSpCas9	negative selection	5563111
41159949	41159972	20	-	27260156	BXPC3	viability	GTTCTTACCTCTCAATCTGCAGG	PLCG1	ENSG00000124181	0.505064972401241	[609]	[949,873,795,1000]	9	hSpCas9	negative selection	5563112
41159916	41159939	20	+	27260156	BXPC3	viability	GCTGATGGAGGATACATTGCAGG	PLCG1	ENSG00000124181	0.2226195518246125	[505]	[591,665,656,540]	5	hSpCas9	negative selection	5563113
41160112	41160135	20	-	27260156	BXPC3	viability	CCACTGAGTAAAACTGCTTCCGG	PLCG1	ENSG00000124181	-0.24122732185877854	[574]	[532,524,478,486]	-5	hSpCas9	negative selection	5627363
41159604	41159627	20	+	27260156	BXPC3	viability	AGTTGACATTCGTGAAATTAAGG	PLCG1	ENSG00000124181	0.01935880793652122	[489]	[481,351,575,700]	0	hSpCas9	negative selection	5627364
41159870	41159893	20	-	27260156	BXPC3	viability	GTTCACTTCATCCTCAGATGTGG	PLCG1	ENSG00000124181	0.22047484036050974	[436]	[515,468,480,682]	5	hSpCas9	negative selection	5627365
41159645	41159668	20	-	27260156	A673	viability	ATAGCGATCAAAGTCCCGTGAGG	PLCG1	ENSG00000124181	-0.26261505247868666	[382]	[471,292,324,459]	-6	hSpCas9	negative selection	5684362
41159949	41159972	20	-	27260156	A673	viability	GTTCTTACCTCTCAATCTGCAGG	PLCG1	ENSG00000124181	0.5575578185847907	[609]	[1150,1036,1075,1053]	9	hSpCas9	negative selection	5684363
41159916	41159939	20	+	27260156	A673	viability	GCTGATGGAGGATACATTGCAGG	PLCG1	ENSG00000124181	0.11994727397206284	[505]	[714,505,738,690]	3	hSpCas9	negative selection	5684364
41160112	41160135	20	-	27260156	A673	viability	CCACTGAGTAAAACTGCTTCCGG	PLCG1	ENSG00000124181	-0.079326589034521	[574]	[834,602,600,592]	-2	hSpCas9	negative selection	5748614
41159604	41159627	20	+	27260156	A673	viability	AGTTGACATTCGTGAAATTAAGG	PLCG1	ENSG00000124181	0.07749768548090144	[489]	[683,538,475,803]	1	hSpCas9	negative selection	5748615
41159870	41159893	20	-	27260156	A673	viability	GTTCACTTCATCCTCAGATGTGG	PLCG1	ENSG00000124181	0.27830382456006125	[436]	[684,626,606,630]	6	hSpCas9	negative selection	5748616
41159645	41159668	20	-	27260156	A375	viability	ATAGCGATCAAAGTCCCGTGAGG	PLCG1	ENSG00000124181	-0.07629248240490505	[382]	[403,641,313,371]	-1	hSpCas9	negative selection	5805613
41159949	41159972	20	-	27260156	A375	viability	GTTCTTACCTCTCAATCTGCAGG	PLCG1	ENSG00000124181	0.7446819800319515	[609]	[822,1572,1344,1091]	9	hSpCas9	negative selection	5805614
41159916	41159939	20	+	27260156	A375	viability	GCTGATGGAGGATACATTGCAGG	PLCG1	ENSG00000124181	-0.06344832579549867	[505]	[412,557,601,671]	-1	hSpCas9	negative selection	5805615
41160112	41160135	20	-	27260156	A375	viability	CCACTGAGTAAAACTGCTTCCGG	PLCG1	ENSG00000124181	-0.1612424571715135	[574]	[887,734,448,375]	-2	hSpCas9	negative selection	5869865
41159604	41159627	20	+	27260156	A375	viability	AGTTGACATTCGTGAAATTAAGG	PLCG1	ENSG00000124181	0.6797639281124752	[489]	[791,1332,858,755]	8	hSpCas9	negative selection	5869866
41159870	41159893	20	-	27260156	A375	viability	GTTCACTTCATCCTCAGATGTGG	PLCG1	ENSG00000124181	-0.1631658057522729	[436]	[496,587,435,333]	-2	hSpCas9	negative selection	5869867
41159645	41159668	20	-	27260156	COLO741	viability	ATAGCGATCAAAGTCCCGTGAGG	PLCG1	ENSG00000124181	0.1802029525685607	[382]	[619,498,548]	4	hSpCas9	negative selection	5926864
41159949	41159972	20	-	27260156	COLO741	viability	GTTCTTACCTCTCAATCTGCAGG	PLCG1	ENSG00000124181	0.4003547467925986	[609]	[1217,1125,774]	7	hSpCas9	negative selection	5926865
41159916	41159939	20	+	27260156	COLO741	viability	GCTGATGGAGGATACATTGCAGG	PLCG1	ENSG00000124181	0.013158279024010067	[505]	[831,545,596]	0	hSpCas9	negative selection	5926866
41160112	41160135	20	-	27260156	COLO741	viability	CCACTGAGTAAAACTGCTTCCGG	PLCG1	ENSG00000124181	-0.17819902792224213	[574]	[792,691,485]	-4	hSpCas9	negative selection	5991116
41159604	41159627	20	+	27260156	COLO741	viability	AGTTGACATTCGTGAAATTAAGG	PLCG1	ENSG00000124181	0.24755638128093407	[489]	[845,707,686]	5	hSpCas9	negative selection	5991117
41159870	41159893	20	-	27260156	COLO741	viability	GTTCACTTCATCCTCAGATGTGG	PLCG1	ENSG00000124181	0.2211745548138093	[436]	[544,768,629]	5	hSpCas9	negative selection	5991118
41159645	41159668	20	-	27260156	CAL120	viability	ATAGCGATCAAAGTCCCGTGAGG	PLCG1	ENSG00000124181	-0.0208453221380957	[382]	[615,283,529]	0	hSpCas9	negative selection	6048115
41159949	41159972	20	-	27260156	CAL120	viability	GTTCTTACCTCTCAATCTGCAGG	PLCG1	ENSG00000124181	0.5732191943348639	[609]	[1274,1083,1051]	8	hSpCas9	negative selection	6048116
41159916	41159939	20	+	27260156	CAL120	viability	GCTGATGGAGGATACATTGCAGG	PLCG1	ENSG00000124181	0.3398436920593021	[505]	[1019,664,739]	5	hSpCas9	negative selection	6048117
41160112	41160135	20	-	27260156	CAL120	viability	CCACTGAGTAAAACTGCTTCCGG	PLCG1	ENSG00000124181	0.011384574735722797	[574]	[964,627,608]	0	hSpCas9	negative selection	6112367
41159604	41159627	20	+	27260156	CAL120	viability	AGTTGACATTCGTGAAATTAAGG	PLCG1	ENSG00000124181	0.1596556777966959	[489]	[724,775,550]	2	hSpCas9	negative selection	6112368
41159870	41159893	20	-	27260156	CAL120	viability	GTTCACTTCATCCTCAGATGTGG	PLCG1	ENSG00000124181	0.2580108934197769	[436]	[813,665,497]	4	hSpCas9	negative selection	6112369
41159645	41159668	20	-	27260156	CADOES1	viability	ATAGCGATCAAAGTCCCGTGAGG	PLCG1	ENSG00000124181	-0.0007899271967531374	[382]	[340,400,305,376]	0	hSpCas9	negative selection	6169366
41159949	41159972	20	-	27260156	CADOES1	viability	GTTCTTACCTCTCAATCTGCAGG	PLCG1	ENSG00000124181	0.5997986095767436	[609]	[835,976,830,792]	8	hSpCas9	negative selection	6169367
41159916	41159939	20	+	27260156	CADOES1	viability	GCTGATGGAGGATACATTGCAGG	PLCG1	ENSG00000124181	0.08911288580308424	[505]	[507,474,449,571]	1	hSpCas9	negative selection	6169368
41160112	41160135	20	-	27260156	CADOES1	viability	CCACTGAGTAAAACTGCTTCCGG	PLCG1	ENSG00000124181	-0.1360565130051395	[574]	[619,445,449,427]	-2	hSpCas9	negative selection	6233618
41159604	41159627	20	+	27260156	CADOES1	viability	AGTTGACATTCGTGAAATTAAGG	PLCG1	ENSG00000124181	0.1521919787822888	[489]	[485,378,436,731]	2	hSpCas9	negative selection	6233619
41159870	41159893	20	-	27260156	CADOES1	viability	GTTCACTTCATCCTCAGATGTGG	PLCG1	ENSG00000124181	0.09894215215714282	[436]	[445,411,525,353]	1	hSpCas9	negative selection	6233620
41159645	41159668	20	-	27260156	EWS502	viability	ATAGCGATCAAAGTCCCGTGAGG	PLCG1	ENSG00000124181	-0.13484206210474808	[382]	[507,330,307,308]	-2	hSpCas9	negative selection	6290617
41159949	41159972	20	-	27260156	EWS502	viability	GTTCTTACCTCTCAATCTGCAGG	PLCG1	ENSG00000124181	0.7398384202386326	[609]	[1047,1079,993,1200]	9	hSpCas9	negative selection	6290618
41159916	41159939	20	+	27260156	EWS502	viability	GCTGATGGAGGATACATTGCAGG	PLCG1	ENSG00000124181	0.24274272495162466	[505]	[571,589,717,666]	4	hSpCas9	negative selection	6290619
41160112	41160135	20	-	27260156	EWS502	viability	CCACTGAGTAAAACTGCTTCCGG	PLCG1	ENSG00000124181	-0.07251860549147318	[574]	[391,466,703,795]	-1	hSpCas9	negative selection	6354869
41159604	41159627	20	+	27260156	EWS502	viability	AGTTGACATTCGTGAAATTAAGG	PLCG1	ENSG00000124181	0.2786067864778586	[489]	[611,724,543,631]	5	hSpCas9	negative selection	6354870
41159870	41159893	20	-	27260156	EWS502	viability	GTTCACTTCATCCTCAGATGTGG	PLCG1	ENSG00000124181	0.3647595690522928	[436]	[409,666,573,761]	6	hSpCas9	negative selection	6354871
41159645	41159668	20	-	27260156	EW8	viability	ATAGCGATCAAAGTCCCGTGAGG	PLCG1	ENSG00000124181	-0.29547349445116733	[382]	[324,229,233,232]	-5	hSpCas9	negative selection	6411868
41159949	41159972	20	-	27260156	EW8	viability	GTTCTTACCTCTCAATCTGCAGG	PLCG1	ENSG00000124181	0.6675929790635364	[609]	[989,893,602,705]	9	hSpCas9	negative selection	6411869
41159916	41159939	20	+	27260156	EW8	viability	GCTGATGGAGGATACATTGCAGG	PLCG1	ENSG00000124181	-0.14324973740096808	[505]	[334,357,286,513]	-3	hSpCas9	negative selection	6411870
41160112	41160135	20	-	27260156	EW8	viability	CCACTGAGTAAAACTGCTTCCGG	PLCG1	ENSG00000124181	0.03265058343102367	[574]	[597,471,355,512]	0	hSpCas9	negative selection	6476120
41159604	41159627	20	+	27260156	EW8	viability	AGTTGACATTCGTGAAATTAAGG	PLCG1	ENSG00000124181	0.37908712318236903	[489]	[783,468,468,379]	7	hSpCas9	negative selection	6476121
41159870	41159893	20	-	27260156	EW8	viability	GTTCACTTCATCCTCAGATGTGG	PLCG1	ENSG00000124181	0.17433645304431528	[436]	[440,506,332,332]	3	hSpCas9	negative selection	6476122
41159645	41159668	20	-	27260156	CORL105	viability	ATAGCGATCAAAGTCCCGTGAGG	PLCG1	ENSG00000124181	-0.0358515522130875	[382]	[451,388,520,401]	0	hSpCas9	negative selection	6533119
41159949	41159972	20	-	27260156	CORL105	viability	GTTCTTACCTCTCAATCTGCAGG	PLCG1	ENSG00000124181	0.5475687885902183	[609]	[981,838,1446,971]	8	hSpCas9	negative selection	6533120
41159916	41159939	20	+	27260156	CORL105	viability	GCTGATGGAGGATACATTGCAGG	PLCG1	ENSG00000124181	-0.12476107578441142	[505]	[530,592,519,523]	-2	hSpCas9	negative selection	6533121
41160112	41160135	20	-	27260156	CORL105	viability	CCACTGAGTAAAACTGCTTCCGG	PLCG1	ENSG00000124181	-0.051821350877819305	[574]	[553,708,700,636]	-1	hSpCas9	negative selection	6597371
41159604	41159627	20	+	27260156	CORL105	viability	AGTTGACATTCGTGAAATTAAGG	PLCG1	ENSG00000124181	-0.12690227673906243	[489]	[551,503,690,381]	-2	hSpCas9	negative selection	6597372
41159870	41159893	20	-	27260156	CORL105	viability	GTTCACTTCATCCTCAGATGTGG	PLCG1	ENSG00000124181	0.18735326367084743	[436]	[691,473,739,454]	3	hSpCas9	negative selection	6597373
41159645	41159668	20	-	27260156	HS294T	viability	ATAGCGATCAAAGTCCCGTGAGG	PLCG1	ENSG00000124181	0.027349958757056037	[382]	[93,99,247,171]	0	hSpCas9	negative selection	6654370
41159949	41159972	20	-	27260156	HS294T	viability	GTTCTTACCTCTCAATCTGCAGG	PLCG1	ENSG00000124181	0.8259502051378143	[609]	[374,534,348,410]	9	hSpCas9	negative selection	6654371
41159916	41159939	20	+	27260156	HS294T	viability	GCTGATGGAGGATACATTGCAGG	PLCG1	ENSG00000124181	-0.5936973781683952	[505]	[101,140,134,144]	-7	hSpCas9	negative selection	6654372
41160112	41160135	20	-	27260156	HS294T	viability	CCACTGAGTAAAACTGCTTCCGG	PLCG1	ENSG00000124181	-0.26001137584849726	[574]	[150,217,210,159]	-4	hSpCas9	negative selection	6718622
41159604	41159627	20	+	27260156	HS294T	viability	AGTTGACATTCGTGAAATTAAGG	PLCG1	ENSG00000124181	-0.19239013719005596	[489]	[127,147,124,285]	-3	hSpCas9	negative selection	6718623
41159870	41159893	20	-	27260156	HS294T	viability	GTTCACTTCATCCTCAGATGTGG	PLCG1	ENSG00000124181	-0.9336259543394906	[436]	[81,71,90,113]	-8	hSpCas9	negative selection	6718624
41159645	41159668	20	-	27260156	HCC44	viability	ATAGCGATCAAAGTCCCGTGAGG	PLCG1	ENSG00000124181	-0.28118778171024905	[382]	[437,279,411,321]	-4	hSpCas9	negative selection	6775621
41159949	41159972	20	-	27260156	HCC44	viability	GTTCTTACCTCTCAATCTGCAGG	PLCG1	ENSG00000124181	0.43038026132904	[609]	[1061,619,1520,674]	7	hSpCas9	negative selection	6775622
41159916	41159939	20	+	27260156	HCC44	viability	GCTGATGGAGGATACATTGCAGG	PLCG1	ENSG00000124181	0.10510875204907164	[505]	[489,367,764,874]	1	hSpCas9	negative selection	6775623
41160112	41160135	20	-	27260156	HCC44	viability	CCACTGAGTAAAACTGCTTCCGG	PLCG1	ENSG00000124181	0.012058817725269788	[574]	[852,406,1036,446]	0	hSpCas9	negative selection	6839873
41159604	41159627	20	+	27260156	HCC44	viability	AGTTGACATTCGTGAAATTAAGG	PLCG1	ENSG00000124181	0.3026376977649798	[489]	[866,534,715,654]	5	hSpCas9	negative selection	6839874
41159870	41159893	20	-	27260156	HCC44	viability	GTTCACTTCATCCTCAGATGTGG	PLCG1	ENSG00000124181	-0.1495406687922729	[436]	[370,328,359,704]	-2	hSpCas9	negative selection	6839875
41159645	41159668	20	-	27260156	G402	viability	ATAGCGATCAAAGTCCCGTGAGG	PLCG1	ENSG00000124181	-1.1072865584257192	[382]	[108,357,186,205]	-8	hSpCas9	negative selection	6896872
41159949	41159972	20	-	27260156	G402	viability	GTTCTTACCTCTCAATCTGCAGG	PLCG1	ENSG00000124181	0.5520119567504578	[609]	[1304,1055,774,1245]	7	hSpCas9	negative selection	6896873
41159916	41159939	20	+	27260156	G402	viability	GCTGATGGAGGATACATTGCAGG	PLCG1	ENSG00000124181	-0.5845762584283345	[505]	[269,238,316,770]	-6	hSpCas9	negative selection	6896874
41160112	41160135	20	-	27260156	G402	viability	CCACTGAGTAAAACTGCTTCCGG	PLCG1	ENSG00000124181	-1.0400826719844725	[574]	[543,177,356,305]	-8	hSpCas9	negative selection	6961124
41159604	41159627	20	+	27260156	G402	viability	AGTTGACATTCGTGAAATTAAGG	PLCG1	ENSG00000124181	0.38457247786719884	[489]	[696,769,806,829]	5	hSpCas9	negative selection	6961125
41159870	41159893	20	-	27260156	G402	viability	GTTCACTTCATCCTCAGATGTGG	PLCG1	ENSG00000124181	-1.0448138363582145	[436]	[278,369,255,142]	-8	hSpCas9	negative selection	6961126
41159645	41159668	20	-	27260156	L33	viability	ATAGCGATCAAAGTCCCGTGAGG	PLCG1	ENSG00000124181	0.20215313965778395	[382]	[422,166,306,443]	4	hSpCas9	negative selection	7018123
41159949	41159972	20	-	27260156	L33	viability	GTTCTTACCTCTCAATCTGCAGG	PLCG1	ENSG00000124181	0.5092077608325509	[609]	[779,332,561,986]	8	hSpCas9	negative selection	7018124
41159916	41159939	20	+	27260156	L33	viability	GCTGATGGAGGATACATTGCAGG	PLCG1	ENSG00000124181	-0.16536528364446898	[505]	[492,190,236,466]	-4	hSpCas9	negative selection	7018125
41160112	41160135	20	-	27260156	L33	viability	CCACTGAGTAAAACTGCTTCCGG	PLCG1	ENSG00000124181	-0.010122107100600186	[574]	[786,183,339,501]	0	hSpCas9	negative selection	7082375
41159604	41159627	20	+	27260156	L33	viability	AGTTGACATTCGTGAAATTAAGG	PLCG1	ENSG00000124181	-0.10036540692170713	[489]	[356,207,300,486]	-2	hSpCas9	negative selection	7082376
41159870	41159893	20	-	27260156	L33	viability	GTTCACTTCATCCTCAGATGTGG	PLCG1	ENSG00000124181	-0.3299519447549923	[436]	[344,112,251,368]	-7	hSpCas9	negative selection	7082377
41159645	41159668	20	-	27260156	K562	viability	ATAGCGATCAAAGTCCCGTGAGG	PLCG1	ENSG00000124181	-0.5442328416740497	[382]	[310,199,163,257]	-6	hSpCas9	negative selection	7139374
41159949	41159972	20	-	27260156	K562	viability	GTTCTTACCTCTCAATCTGCAGG	PLCG1	ENSG00000124181	0.9083860181009622	[609]	[1093,1277,1125,627]	9	hSpCas9	negative selection	7139375
41159916	41159939	20	+	27260156	K562	viability	GCTGATGGAGGATACATTGCAGG	PLCG1	ENSG00000124181	0.24210803136245077	[505]	[326,740,739,331]	3	hSpCas9	negative selection	7139376
41160112	41160135	20	-	27260156	K562	viability	CCACTGAGTAAAACTGCTTCCGG	PLCG1	ENSG00000124181	-0.2018100346496227	[574]	[462,808,289,253]	-3	hSpCas9	negative selection	7203626
41159604	41159627	20	+	27260156	K562	viability	AGTTGACATTCGTGAAATTAAGG	PLCG1	ENSG00000124181	0.24463753470282348	[489]	[389,830,404,446]	3	hSpCas9	negative selection	7203627
41159870	41159893	20	-	27260156	K562	viability	GTTCACTTCATCCTCAGATGTGG	PLCG1	ENSG00000124181	-0.49089149109180064	[436]	[372,184,150,383]	-5	hSpCas9	negative selection	7203628
41159645	41159668	20	-	27260156	HT29	viability	ATAGCGATCAAAGTCCCGTGAGG	PLCG1	ENSG00000124181	-0.13280905216675154	[382]	[487,322,378,492]	-3	hSpCas9	negative selection	7260625
41159949	41159972	20	-	27260156	HT29	viability	GTTCTTACCTCTCAATCTGCAGG	PLCG1	ENSG00000124181	0.5461244136818644	[609]	[1015,1112,1139,1054]	9	hSpCas9	negative selection	7260626
41159916	41159939	20	+	27260156	HT29	viability	GCTGATGGAGGATACATTGCAGG	PLCG1	ENSG00000124181	0.12430531009755388	[505]	[786,680,711,524]	2	hSpCas9	negative selection	7260627
41160112	41160135	20	-	27260156	HT29	viability	CCACTGAGTAAAACTGCTTCCGG	PLCG1	ENSG00000124181	0.10622530674230002	[574]	[887,678,785,665]	2	hSpCas9	negative selection	7324877
41159604	41159627	20	+	27260156	HT29	viability	AGTTGACATTCGTGAAATTAAGG	PLCG1	ENSG00000124181	-0.017740021132447548	[489]	[719,676,525,459]	0	hSpCas9	negative selection	7324878
41159870	41159893	20	-	27260156	HT29	viability	GTTCACTTCATCCTCAGATGTGG	PLCG1	ENSG00000124181	0.2856624106327282	[436]	[702,666,713,522]	5	hSpCas9	negative selection	7324879
41159645	41159668	20	-	27260156	MHHES1	viability	ATAGCGATCAAAGTCCCGTGAGG	PLCG1	ENSG00000124181	0.07284135824493096	[382]	[631,524,425,288]	1	hSpCas9	negative selection	7381876
41159949	41159972	20	-	27260156	MHHES1	viability	GTTCTTACCTCTCAATCTGCAGG	PLCG1	ENSG00000124181	0.5898554710944506	[609]	[1268,1331,1051,616]	8	hSpCas9	negative selection	7381877
41159916	41159939	20	+	27260156	MHHES1	viability	GCTGATGGAGGATACATTGCAGG	PLCG1	ENSG00000124181	-0.04344038427545696	[505]	[629,814,503,336]	-1	hSpCas9	negative selection	7381878
41160112	41160135	20	-	27260156	MHHES1	viability	CCACTGAGTAAAACTGCTTCCGG	PLCG1	ENSG00000124181	-0.3379703235459885	[574]	[389,516,620,498]	-6	hSpCas9	negative selection	7446128
41159604	41159627	20	+	27260156	MHHES1	viability	AGTTGACATTCGTGAAATTAAGG	PLCG1	ENSG00000124181	0.2967561799037168	[489]	[1180,527,502,556]	5	hSpCas9	negative selection	7446129
41159870	41159893	20	-	27260156	MHHES1	viability	GTTCACTTCATCCTCAGATGTGG	PLCG1	ENSG00000124181	0.2035545928481993	[436]	[829,554,513,419]	4	hSpCas9	negative selection	7446130
41159645	41159668	20	-	27260156	MEWO	viability	ATAGCGATCAAAGTCCCGTGAGG	PLCG1	ENSG00000124181	0.08101182725104666	[382]	[527,343,293]	1	hSpCas9	negative selection	7503127
41159949	41159972	20	-	27260156	MEWO	viability	GTTCTTACCTCTCAATCTGCAGG	PLCG1	ENSG00000124181	0.4453382973731756	[609]	[1052,675,655]	8	hSpCas9	negative selection	7503128
41159916	41159939	20	+	27260156	MEWO	viability	GCTGATGGAGGATACATTGCAGG	PLCG1	ENSG00000124181	0.13756534673470064	[505]	[561,549,457]	3	hSpCas9	negative selection	7503129
41160112	41160135	20	-	27260156	MEWO	viability	CCACTGAGTAAAACTGCTTCCGG	PLCG1	ENSG00000124181	-0.24687645603467465	[574]	[391,459,495]	-5	hSpCas9	negative selection	7567379
41159604	41159627	20	+	27260156	MEWO	viability	AGTTGACATTCGTGAAATTAAGG	PLCG1	ENSG00000124181	0.135060304973865	[489]	[611,537,380]	3	hSpCas9	negative selection	7567380
41159870	41159893	20	-	27260156	MEWO	viability	GTTCACTTCATCCTCAGATGTGG	PLCG1	ENSG00000124181	0.22735559310827747	[436]	[720,421,339]	5	hSpCas9	negative selection	7567381
41159645	41159668	20	-	27260156	LNCAPCLONEFGC	viability	ATAGCGATCAAAGTCCCGTGAGG	PLCG1	ENSG00000124181	-0.17707543051604985	[382]	[229,260,469,294]	-3	hSpCas9	negative selection	7624378
41159949	41159972	20	-	27260156	LNCAPCLONEFGC	viability	GTTCTTACCTCTCAATCTGCAGG	PLCG1	ENSG00000124181	0.5743443788368723	[609]	[962,810,784,723]	8	hSpCas9	negative selection	7624379
41159916	41159939	20	+	27260156	LNCAPCLONEFGC	viability	GCTGATGGAGGATACATTGCAGG	PLCG1	ENSG00000124181	0.019429193739579492	[505]	[454,389,510,513]	0	hSpCas9	negative selection	7624380
41160112	41160135	20	-	27260156	LNCAPCLONEFGC	viability	CCACTGAGTAAAACTGCTTCCGG	PLCG1	ENSG00000124181	-0.21564684108108742	[574]	[397,437,565,410]	-3	hSpCas9	negative selection	7688630
41159604	41159627	20	+	27260156	LNCAPCLONEFGC	viability	AGTTGACATTCGTGAAATTAAGG	PLCG1	ENSG00000124181	0.4219206767662112	[489]	[731,505,692,464]	6	hSpCas9	negative selection	7688631
41159870	41159893	20	-	27260156	LNCAPCLONEFGC	viability	GTTCACTTCATCCTCAGATGTGG	PLCG1	ENSG00000124181	-0.024980572316324348	[436]	[404,238,539,403]	0	hSpCas9	negative selection	7688632
41159645	41159668	20	-	27260156	PANC0327	viability	ATAGCGATCAAAGTCCCGTGAGG	PLCG1	ENSG00000124181	-0.3246236542871681	[382]	[233,244,310,296]	-5	hSpCas9	negative selection	7745629
41159949	41159972	20	-	27260156	PANC0327	viability	GTTCTTACCTCTCAATCTGCAGG	PLCG1	ENSG00000124181	0.3577039745890553	[609]	[819,811,509,629]	5	hSpCas9	negative selection	7745630
41159916	41159939	20	+	27260156	PANC0327	viability	GCTGATGGAGGATACATTGCAGG	PLCG1	ENSG00000124181	0.3834111542437171	[505]	[672,755,385,514]	5	hSpCas9	negative selection	7745631
41160112	41160135	20	-	27260156	PANC0327	viability	CCACTGAGTAAAACTGCTTCCGG	PLCG1	ENSG00000124181	-0.38876418071352964	[574]	[673,416,230,257]	-5	hSpCas9	negative selection	7809881
41159604	41159627	20	+	27260156	PANC0327	viability	AGTTGACATTCGTGAAATTAAGG	PLCG1	ENSG00000124181	0.5091920896509783	[489]	[982,665,248,602]	7	hSpCas9	negative selection	7809882
41159870	41159893	20	-	27260156	PANC0327	viability	GTTCACTTCATCCTCAGATGTGG	PLCG1	ENSG00000124181	-0.14047039533508526	[436]	[272,274,368,494]	-2	hSpCas9	negative selection	7809883
41159645	41159668	20	-	27260156	NCIH2009	viability	ATAGCGATCAAAGTCCCGTGAGG	PLCG1	ENSG00000124181	0.04934052226544838	[382]	[824,380,510]	0	hSpCas9	negative selection	7866880
41159949	41159972	20	-	27260156	NCIH2009	viability	GTTCTTACCTCTCAATCTGCAGG	PLCG1	ENSG00000124181	0.7115819031039328	[609]	[2010,1299,996]	8	hSpCas9	negative selection	7866881
41159916	41159939	20	+	27260156	NCIH2009	viability	GCTGATGGAGGATACATTGCAGG	PLCG1	ENSG00000124181	-0.024099291209702903	[505]	[978,510,653]	0	hSpCas9	negative selection	7866882
41160112	41160135	20	-	27260156	NCIH2009	viability	CCACTGAGTAAAACTGCTTCCGG	PLCG1	ENSG00000124181	-0.29514283016341697	[574]	[635,455,870]	-4	hSpCas9	negative selection	7931132
41159604	41159627	20	+	27260156	NCIH2009	viability	AGTTGACATTCGTGAAATTAAGG	PLCG1	ENSG00000124181	0.4753053500536259	[489]	[1054,1008,808]	6	hSpCas9	negative selection	7931133
41159870	41159893	20	-	27260156	NCIH2009	viability	GTTCACTTCATCCTCAGATGTGG	PLCG1	ENSG00000124181	0.2018377485792635	[436]	[780,376,968]	2	hSpCas9	negative selection	7931134
41159645	41159668	20	-	27260156	NCIH1373	viability	ATAGCGATCAAAGTCCCGTGAGG	PLCG1	ENSG00000124181	-0.028996614192439873	[382]	[407,649,398,47]	0	hSpCas9	negative selection	7988131
41159949	41159972	20	-	27260156	NCIH1373	viability	GTTCTTACCTCTCAATCTGCAGG	PLCG1	ENSG00000124181	1.0092715726879289	[609]	[1612,1583,1194,290]	8	hSpCas9	negative selection	7988132
41159916	41159939	20	+	27260156	NCIH1373	viability	GCTGATGGAGGATACATTGCAGG	PLCG1	ENSG00000124181	-0.29296360421999035	[505]	[372,444,692,81]	-3	hSpCas9	negative selection	7988133
41160112	41160135	20	-	27260156	NCIH1373	viability	CCACTGAGTAAAACTGCTTCCGG	PLCG1	ENSG00000124181	-0.3044606579662933	[574]	[378,463,675,143]	-3	hSpCas9	negative selection	8052383
41159604	41159627	20	+	27260156	NCIH1373	viability	AGTTGACATTCGTGAAATTAAGG	PLCG1	ENSG00000124181	0.30028385206132546	[489]	[564,884,697,131]	3	hSpCas9	negative selection	8052384
41159870	41159893	20	-	27260156	NCIH1373	viability	GTTCACTTCATCCTCAGATGTGG	PLCG1	ENSG00000124181	-0.287079597756222	[436]	[266,215,723,101]	-3	hSpCas9	negative selection	8052385
41159645	41159668	20	-	27260156	PATU8902	viability	ATAGCGATCAAAGTCCCGTGAGG	PLCG1	ENSG00000124181	-0.12402706671441727	[382]	[403,593,566,353]	-1	hSpCas9	negative selection	8109382
41159949	41159972	20	-	27260156	PATU8902	viability	GTTCTTACCTCTCAATCTGCAGG	PLCG1	ENSG00000124181	1.149978475093902	[609]	[1494,2377,1303,2590]	9	hSpCas9	negative selection	8109383
41159916	41159939	20	+	27260156	PATU8902	viability	GCTGATGGAGGATACATTGCAGG	PLCG1	ENSG00000124181	0.5354129740008804	[505]	[753,908,1216,1166]	5	hSpCas9	negative selection	8109384
41160112	41160135	20	-	27260156	PATU8902	viability	CCACTGAGTAAAACTGCTTCCGG	PLCG1	ENSG00000124181	0.1490906416860348	[574]	[583,824,683,1592]	1	hSpCas9	negative selection	8173634
41159604	41159627	20	+	27260156	PATU8902	viability	AGTTGACATTCGTGAAATTAAGG	PLCG1	ENSG00000124181	0.5772655600961227	[489]	[682,1287,735,1492]	6	hSpCas9	negative selection	8173635
41159870	41159893	20	-	27260156	PATU8902	viability	GTTCACTTCATCCTCAGATGTGG	PLCG1	ENSG00000124181	0.5862251848460682	[436]	[315,1622,808,939]	6	hSpCas9	negative selection	8173636
41159645	41159668	20	-	27260156	PANC1	viability	ATAGCGATCAAAGTCCCGTGAGG	PLCG1	ENSG00000124181	0.8314552439587142	[382]	[466,720,534,630]	9	hSpCas9	negative selection	8230633
41159949	41159972	20	-	27260156	PANC1	viability	GTTCTTACCTCTCAATCTGCAGG	PLCG1	ENSG00000124181	0.7345216432734938	[609]	[1065,960,968,545]	9	hSpCas9	negative selection	8230634
41159916	41159939	20	+	27260156	PANC1	viability	GCTGATGGAGGATACATTGCAGG	PLCG1	ENSG00000124181	0.313506681966498	[505]	[549,551,568,490]	5	hSpCas9	negative selection	8230635
41160112	41160135	20	-	27260156	PANC1	viability	CCACTGAGTAAAACTGCTTCCGG	PLCG1	ENSG00000124181	0.16552624195720766	[574]	[462,806,538,465]	2	hSpCas9	negative selection	8294885
41159604	41159627	20	+	27260156	PANC1	viability	AGTTGACATTCGTGAAATTAAGG	PLCG1	ENSG00000124181	-0.035381735387713414	[489]	[413,482,335,415]	0	hSpCas9	negative selection	8294886
41159870	41159893	20	-	27260156	PANC1	viability	GTTCACTTCATCCTCAGATGTGG	PLCG1	ENSG00000124181	0.7873367046476513	[436]	[651,939,423,625]	9	hSpCas9	negative selection	8294887
41159645	41159668	20	-	27260156	PANC0813	viability	ATAGCGATCAAAGTCCCGTGAGG	PLCG1	ENSG00000124181	0.3231411918269236	[382]	[677,535,660,395]	5	hSpCas9	negative selection	8351884
41159949	41159972	20	-	27260156	PANC0813	viability	GTTCTTACCTCTCAATCTGCAGG	PLCG1	ENSG00000124181	0.8085998584718417	[609]	[906,1438,1465,1178]	9	hSpCas9	negative selection	8351885
41159916	41159939	20	+	27260156	PANC0813	viability	GCTGATGGAGGATACATTGCAGG	PLCG1	ENSG00000124181	-0.15247528082469214	[505]	[513,471,518,625]	-2	hSpCas9	negative selection	8351886
41160112	41160135	20	-	27260156	PANC0813	viability	CCACTGAGTAAAACTGCTTCCGG	PLCG1	ENSG00000124181	-0.3446495283934007	[574]	[558,472,352,731]	-5	hSpCas9	negative selection	8416136
41159604	41159627	20	+	27260156	PANC0813	viability	AGTTGACATTCGTGAAATTAAGG	PLCG1	ENSG00000124181	0.001684861344857791	[489]	[496,621,484,685]	0	hSpCas9	negative selection	8416137
41159870	41159893	20	-	27260156	PANC0813	viability	GTTCACTTCATCCTCAGATGTGG	PLCG1	ENSG00000124181	-0.0076600911535121	[436]	[616,558,575,310]	0	hSpCas9	negative selection	8416138
41159645	41159668	20	-	27260156	RDES	viability	ATAGCGATCAAAGTCCCGTGAGG	PLCG1	ENSG00000124181	-0.07609440281411645	[382]	[340,308,619,424]	-1	hSpCas9	negative selection	8473135
41159949	41159972	20	-	27260156	RDES	viability	GTTCTTACCTCTCAATCTGCAGG	PLCG1	ENSG00000124181	0.6983080301295108	[609]	[1049,1094,1042,1384]	9	hSpCas9	negative selection	8473136
41159916	41159939	20	+	27260156	RDES	viability	GCTGATGGAGGATACATTGCAGG	PLCG1	ENSG00000124181	0.059365958593234014	[505]	[430,505,620,951]	1	hSpCas9	negative selection	8473137
41160112	41160135	20	-	27260156	RDES	viability	CCACTGAGTAAAACTGCTTCCGG	PLCG1	ENSG00000124181	-0.23666454714675828	[574]	[428,550,699,586]	-4	hSpCas9	negative selection	8537387
41159604	41159627	20	+	27260156	RDES	viability	AGTTGACATTCGTGAAATTAAGG	PLCG1	ENSG00000124181	0.4146707796543736	[489]	[540,742,738,1051]	6	hSpCas9	negative selection	8537388
41159870	41159893	20	-	27260156	RDES	viability	GTTCACTTCATCCTCAGATGTGG	PLCG1	ENSG00000124181	-0.11883374985486266	[436]	[480,402,512,437]	-2	hSpCas9	negative selection	8537389
41159645	41159668	20	-	27260156	PC3	viability	ATAGCGATCAAAGTCCCGTGAGG	PLCG1	ENSG00000124181	-0.2007017252965586	[382]	[242,310,566,300]	-4	hSpCas9	negative selection	8594386
41159949	41159972	20	-	27260156	PC3	viability	GTTCTTACCTCTCAATCTGCAGG	PLCG1	ENSG00000124181	0.20751610893739386	[609]	[529,601,977,810]	4	hSpCas9	negative selection	8594387
41159916	41159939	20	+	27260156	PC3	viability	GCTGATGGAGGATACATTGCAGG	PLCG1	ENSG00000124181	-0.001922228643012197	[505]	[282,455,758,678]	0	hSpCas9	negative selection	8594388
41160112	41160135	20	-	27260156	PC3	viability	CCACTGAGTAAAACTGCTTCCGG	PLCG1	ENSG00000124181	-0.04370190292683379	[574]	[366,528,931,570]	-1	hSpCas9	negative selection	8658638
41159604	41159627	20	+	27260156	PC3	viability	AGTTGACATTCGTGAAATTAAGG	PLCG1	ENSG00000124181	0.16701071057548153	[489]	[318,564,748,693]	4	hSpCas9	negative selection	8658639
41159870	41159893	20	-	27260156	PC3	viability	GTTCACTTCATCCTCAGATGTGG	PLCG1	ENSG00000124181	0.026616881829854916	[436]	[269,380,644,601]	0	hSpCas9	negative selection	8658640
41159645	41159668	20	-	27260156	PATU8988T	viability	ATAGCGATCAAAGTCCCGTGAGG	PLCG1	ENSG00000124181	0.11996348227758602	[382]	[198,449,519,445]	2	hSpCas9	negative selection	8715637
41159949	41159972	20	-	27260156	PATU8988T	viability	GTTCTTACCTCTCAATCTGCAGG	PLCG1	ENSG00000124181	0.30907524998370145	[609]	[589,693,882,749]	5	hSpCas9	negative selection	8715638
41159916	41159939	20	+	27260156	PATU8988T	viability	GCTGATGGAGGATACATTGCAGG	PLCG1	ENSG00000124181	0.03309954289728878	[505]	[459,496,446,605]	0	hSpCas9	negative selection	8715639
41160112	41160135	20	-	27260156	PATU8988T	viability	CCACTGAGTAAAACTGCTTCCGG	PLCG1	ENSG00000124181	-0.037941419213048055	[574]	[500,496,487,686]	0	hSpCas9	negative selection	8779889
41159604	41159627	20	+	27260156	PATU8988T	viability	AGTTGACATTCGTGAAATTAAGG	PLCG1	ENSG00000124181	-0.3442805121885389	[489]	[226,562,404,308]	-5	hSpCas9	negative selection	8779890
41159870	41159893	20	-	27260156	PATU8988T	viability	GTTCACTTCATCCTCAGATGTGG	PLCG1	ENSG00000124181	-0.028387746763572433	[436]	[359,297,639,337]	0	hSpCas9	negative selection	8779891
41159645	41159668	20	-	27260156	T47D	viability	ATAGCGATCAAAGTCCCGTGAGG	PLCG1	ENSG00000124181	-0.09971958751063059	[382]	[394,386,469,414]	-2	hSpCas9	negative selection	8836888
41159949	41159972	20	-	27260156	T47D	viability	GTTCTTACCTCTCAATCTGCAGG	PLCG1	ENSG00000124181	0.47856273906205254	[609]	[1058,864,1005,1042]	8	hSpCas9	negative selection	8836889
41159916	41159939	20	+	27260156	T47D	viability	GCTGATGGAGGATACATTGCAGG	PLCG1	ENSG00000124181	-0.021260832525871756	[505]	[624,531,620,547]	0	hSpCas9	negative selection	8836890
41160112	41160135	20	-	27260156	T47D	viability	CCACTGAGTAAAACTGCTTCCGG	PLCG1	ENSG00000124181	-0.33001689459084393	[574]	[529,492,621,486]	-6	hSpCas9	negative selection	8901140
41159604	41159627	20	+	27260156	T47D	viability	AGTTGACATTCGTGAAATTAAGG	PLCG1	ENSG00000124181	0.16153639358230246	[489]	[694,568,670,623]	3	hSpCas9	negative selection	8901141
41159870	41159893	20	-	27260156	T47D	viability	GTTCACTTCATCCTCAGATGTGG	PLCG1	ENSG00000124181	-0.1074177525976711	[436]	[457,424,459,553]	-2	hSpCas9	negative selection	8901142
41159645	41159668	20	-	27260156	SU8686	viability	ATAGCGATCAAAGTCCCGTGAGG	PLCG1	ENSG00000124181	0.26083540579228426	[382]	[452,466,362,543]	4	hSpCas9	negative selection	8958139
41159949	41159972	20	-	27260156	SU8686	viability	GTTCTTACCTCTCAATCTGCAGG	PLCG1	ENSG00000124181	0.6721330994717922	[609]	[948,768,1006,1186]	9	hSpCas9	negative selection	8958140
41159916	41159939	20	+	27260156	SU8686	viability	GCTGATGGAGGATACATTGCAGG	PLCG1	ENSG00000124181	0.2264518977392009	[505]	[482,501,639,772]	4	hSpCas9	negative selection	8958141
41160112	41160135	20	-	27260156	SU8686	viability	CCACTGAGTAAAACTGCTTCCGG	PLCG1	ENSG00000124181	-0.1711917862929648	[574]	[501,393,557,598]	-3	hSpCas9	negative selection	9022391
41159604	41159627	20	+	27260156	SU8686	viability	AGTTGACATTCGTGAAATTAAGG	PLCG1	ENSG00000124181	0.11807014299741142	[489]	[438,548,419,734]	2	hSpCas9	negative selection	9022392
41159870	41159893	20	-	27260156	SU8686	viability	GTTCACTTCATCCTCAGATGTGG	PLCG1	ENSG00000124181	-0.025123587043393222	[436]	[393,387,344,608]	0	hSpCas9	negative selection	9022393
41159645	41159668	20	-	27260156	SKES1	viability	ATAGCGATCAAAGTCCCGTGAGG	PLCG1	ENSG00000124181	-0.010036640179178102	[382]	[546,382,330,287]	0	hSpCas9	negative selection	9079390
41159949	41159972	20	-	27260156	SKES1	viability	GTTCTTACCTCTCAATCTGCAGG	PLCG1	ENSG00000124181	0.502088133850344	[609]	[941,795,805,893]	8	hSpCas9	negative selection	9079391
41159916	41159939	20	+	27260156	SKES1	viability	GCTGATGGAGGATACATTGCAGG	PLCG1	ENSG00000124181	0.021002318425218935	[505]	[544,546,471,490]	0	hSpCas9	negative selection	9079392
41160112	41160135	20	-	27260156	SKES1	viability	CCACTGAGTAAAACTGCTTCCGG	PLCG1	ENSG00000124181	-0.11398000394395741	[574]	[714,740,442,295]	-2	hSpCas9	negative selection	9143642
41159604	41159627	20	+	27260156	SKES1	viability	AGTTGACATTCGTGAAATTAAGG	PLCG1	ENSG00000124181	0.05635652133749464	[489]	[571,459,366,619]	1	hSpCas9	negative selection	9143643
41159870	41159893	20	-	27260156	SKES1	viability	GTTCACTTCATCCTCAGATGTGG	PLCG1	ENSG00000124181	0.2082125571401582	[436]	[601,490,464,467]	4	hSpCas9	negative selection	9143644
41159645	41159668	20	-	27260156	TOV112D	viability	ATAGCGATCAAAGTCCCGTGAGG	PLCG1	ENSG00000124181	-0.2845218726421206	[382]	[297,377,270,325]	-5	hSpCas9	negative selection	9200641
41159949	41159972	20	-	27260156	TOV112D	viability	GTTCTTACCTCTCAATCTGCAGG	PLCG1	ENSG00000124181	0.6634983744827787	[609]	[1318,1079,799,733]	9	hSpCas9	negative selection	9200642
41159916	41159939	20	+	27260156	TOV112D	viability	GCTGATGGAGGATACATTGCAGG	PLCG1	ENSG00000124181	0.04306843184671921	[505]	[358,588,713,430]	0	hSpCas9	negative selection	9200643
41160112	41160135	20	-	27260156	TOV112D	viability	CCACTGAGTAAAACTGCTTCCGG	PLCG1	ENSG00000124181	-0.17310797292667268	[574]	[512,480,489,549]	-3	hSpCas9	negative selection	9264893
41159604	41159627	20	+	27260156	TOV112D	viability	AGTTGACATTCGTGAAATTAAGG	PLCG1	ENSG00000124181	-0.02571234517216968	[489]	[457,539,394,544]	0	hSpCas9	negative selection	9264894
41159870	41159893	20	-	27260156	TOV112D	viability	GTTCACTTCATCCTCAGATGTGG	PLCG1	ENSG00000124181	0.07166823840040931	[436]	[350,662,481,385]	1	hSpCas9	negative selection	9264895
41159645	41159668	20	-	27260156	TC71	viability	ATAGCGATCAAAGTCCCGTGAGG	PLCG1	ENSG00000124181	-0.08781317039683456	[382]	[395,468,285,397]	-2	hSpCas9	negative selection	9321892
41159949	41159972	20	-	27260156	TC71	viability	GTTCTTACCTCTCAATCTGCAGG	PLCG1	ENSG00000124181	0.4022224595572336	[609]	[964,732,784,980]	8	hSpCas9	negative selection	9321893
41159916	41159939	20	+	27260156	TC71	viability	GCTGATGGAGGATACATTGCAGG	PLCG1	ENSG00000124181	0.07554113889923836	[505]	[541,609,504,635]	2	hSpCas9	negative selection	9321894
41160112	41160135	20	-	27260156	TC71	viability	CCACTGAGTAAAACTGCTTCCGG	PLCG1	ENSG00000124181	-0.061317568846484455	[574]	[468,680,667,541]	-1	hSpCas9	negative selection	9386144
41159604	41159627	20	+	27260156	TC71	viability	AGTTGACATTCGTGAAATTAAGG	PLCG1	ENSG00000124181	0.04541455945055924	[489]	[574,525,623,432]	1	hSpCas9	negative selection	9386145
41159870	41159893	20	-	27260156	TC71	viability	GTTCACTTCATCCTCAGATGTGG	PLCG1	ENSG00000124181	0.25952362150559666	[436]	[633,457,641,500]	6	hSpCas9	negative selection	9386146
41159645	41159668	20	-	27260156	TC32	viability	ATAGCGATCAAAGTCCCGTGAGG	PLCG1	ENSG00000124181	0.12972916621329794	[382]	[393,313,505,385]	2	hSpCas9	negative selection	9443143
41159949	41159972	20	-	27260156	TC32	viability	GTTCTTACCTCTCAATCTGCAGG	PLCG1	ENSG00000124181	0.8494013792130417	[609]	[853,875,1138,1315]	9	hSpCas9	negative selection	9443144
41159916	41159939	20	+	27260156	TC32	viability	GCTGATGGAGGATACATTGCAGG	PLCG1	ENSG00000124181	0.26898470771603966	[505]	[562,426,777,581]	5	hSpCas9	negative selection	9443145
41160112	41160135	20	-	27260156	TC32	viability	CCACTGAGTAAAACTGCTTCCGG	PLCG1	ENSG00000124181	-0.06860851308569635	[574]	[336,466,577,710]	-1	hSpCas9	negative selection	9507395
41159604	41159627	20	+	27260156	TC32	viability	AGTTGACATTCGTGAAATTAAGG	PLCG1	ENSG00000124181	0.5317339223056167	[489]	[777,428,686,815]	8	hSpCas9	negative selection	9507396
41159870	41159893	20	-	27260156	TC32	viability	GTTCACTTCATCCTCAGATGTGG	PLCG1	ENSG00000124181	0.07013623469502611	[436]	[411,382,500,433]	1	hSpCas9	negative selection	9507397
41137833	41137856	20	+	27869803	HPAFII	viability after 27 days	GGGCGCCGACAAGATCGAGGGGG	PLCG1	ENSG00000124181	-0.7909613923170082	[256]	[34,113,NaN]	-5	hSpCas9	negative selection	9577607
41159618	41159641	20	+	27869803	HPAFII	viability after 27 days	AAATTAAGGAGATCCGCCCAGGG	PLCG1	ENSG00000124181	-1.180776723714715	[97]	[13,29,NaN]	-7	hSpCas9	negative selection	9577608
41160102	41160125	20	-	27869803	HPAFII	viability after 27 days	AAACTGCTTCCGGAGCCACCTGG	PLCG1	ENSG00000124181	1.3532624889516731	[88]	[142,99,NaN]	9	hSpCas9	negative selection	9577609
41162626	41162649	20	+	27869803	HPAFII	viability after 27 days	GCTCTATACCATGCAGGACCTGG	PLCG1	ENSG00000124181	0.6624791498489964	[253]	[272,159,NaN]	5	hSpCas9	negative selection	9577610
41162966	41162989	20	-	27869803	HPAFII	viability after 27 days	GAGTACTGGCTTCCAAGAAGGGG	PLCG1	ENSG00000124181	0.16770046826149534	[249]	[175,123,NaN]	1	hSpCas9	negative selection	9577611
41163252	41163275	20	+	27869803	HPAFII	viability after 27 days	CAGTTCCTTCTTGACTACCAGGG	PLCG1	ENSG00000124181	0.055325757525004376	[216]	[147,93,NaN]	0	hSpCas9	negative selection	9577612
41137833	41137856	20	+	27869803	HPAFII	viability after 15 days	GGGCGCCGACAAGATCGAGGGGG	PLCG1	ENSG00000124181	-0.5755606648651612	[256]	[90,243,NaN]	-6	hSpCas9	negative selection	9660056
41159618	41159641	20	+	27869803	HPAFII	viability after 15 days	AAATTAAGGAGATCCGCCCAGGG	PLCG1	ENSG00000124181	0.2017792033043937	[97]	[130,114,NaN]	2	hSpCas9	negative selection	9660057
41160102	41160125	20	-	27869803	HPAFII	viability after 15 days	AAACTGCTTCCGGAGCCACCTGG	PLCG1	ENSG00000124181	1.4087662182549094	[88]	[388,169,NaN]	9	hSpCas9	negative selection	9660058
41162626	41162649	20	+	27869803	HPAFII	viability after 15 days	GCTCTATACCATGCAGGACCTGG	PLCG1	ENSG00000124181	0.15531884989212882	[253]	[414,234,NaN]	1	hSpCas9	negative selection	9660059
41162966	41162989	20	-	27869803	HPAFII	viability after 15 days	GAGTACTGGCTTCCAAGAAGGGG	PLCG1	ENSG00000124181	0.07660096062708602	[249]	[463,170,NaN]	0	hSpCas9	negative selection	9660060
41163252	41163275	20	+	27869803	HPAFII	viability after 15 days	CAGTTCCTTCTTGACTACCAGGG	PLCG1	ENSG00000124181	0.28385357686934537	[216]	[397,212,NaN]	3	hSpCas9	negative selection	9660061
41137833	41137856	20	+	27869803	ASPC1	viability after 36 days	GGGCGCCGACAAGATCGAGGGGG	PLCG1	ENSG00000124181	0.704439336447514	[439]	[40,299,354]	7	hSpCas9	negative selection	9742505
41159618	41159641	20	+	27869803	ASPC1	viability after 36 days	AAATTAAGGAGATCCGCCCAGGG	PLCG1	ENSG00000124181	1.1220764419542826	[268]	[356,191,104]	9	hSpCas9	negative selection	9742506
41160102	41160125	20	-	27869803	ASPC1	viability after 36 days	AAACTGCTTCCGGAGCCACCTGG	PLCG1	ENSG00000124181	-0.44556495947500063	[294]	[97,8,111]	-4	hSpCas9	negative selection	9742507
41162626	41162649	20	+	27869803	ASPC1	viability after 36 days	GCTCTATACCATGCAGGACCTGG	PLCG1	ENSG00000124181	-0.5034704194504079	[444]	[122,130,81]	-5	hSpCas9	negative selection	9742508
41162966	41162989	20	-	27869803	ASPC1	viability after 36 days	GAGTACTGGCTTCCAAGAAGGGG	PLCG1	ENSG00000124181	-0.10712340159140465	[868]	[403,225,236]	-1	hSpCas9	negative selection	9742509
41163252	41163275	20	+	27869803	ASPC1	viability after 36 days	CAGTTCCTTCTTGACTACCAGGG	PLCG1	ENSG00000124181	0.5839425732823044	[634]	[391,452,190]	6	hSpCas9	negative selection	9742510
41137833	41137856	20	+	27869803	PATU8988S	viability after 35 days	GGGCGCCGACAAGATCGAGGGGG	PLCG1	ENSG00000124181	-1.0615324952458358	[385]	[67,80,NaN]	-7	hSpCas9	negative selection	9824954
41159618	41159641	20	+	27869803	PATU8988S	viability after 35 days	AAATTAAGGAGATCCGCCCAGGG	PLCG1	ENSG00000124181	-0.39980534665042433	[230]	[77,62,NaN]	-4	hSpCas9	negative selection	9824955
41160102	41160125	20	-	27869803	PATU8988S	viability after 35 days	AAACTGCTTCCGGAGCCACCTGG	PLCG1	ENSG00000124181	-1.0781467026068197	[298]	[72,40,NaN]	-7	hSpCas9	negative selection	9824956
41162626	41162649	20	+	27869803	PATU8988S	viability after 35 days	GCTCTATACCATGCAGGACCTGG	PLCG1	ENSG00000124181	0.06684317107668536	[421]	[186,168,NaN]	0	hSpCas9	negative selection	9824957
41162966	41162989	20	-	27869803	PATU8988S	viability after 35 days	GAGTACTGGCTTCCAAGAAGGGG	PLCG1	ENSG00000124181	0.5084733011621463	[677]	[364,411,NaN]	5	hSpCas9	negative selection	9824958
41163252	41163275	20	+	27869803	PATU8988S	viability after 35 days	CAGTTCCTTCTTGACTACCAGGG	PLCG1	ENSG00000124181	0.2775676509231407	[507]	[248,246,NaN]	3	hSpCas9	negative selection	9824959
41137833	41137856	20	+	27869803	PATU8988S	viability after 31 days	GGGCGCCGACAAGATCGAGGGGG	PLCG1	ENSG00000124181	-1.9413653529918162	[385]	[14,71,NaN]	-9	hSpCas9	negative selection	9907403
41159618	41159641	20	+	27869803	PATU8988S	viability after 31 days	AAATTAAGGAGATCCGCCCAGGG	PLCG1	ENSG00000124181	-0.28963119467892673	[230]	[55,99,NaN]	-3	hSpCas9	negative selection	9907404
41160102	41160125	20	-	27869803	PATU8988S	viability after 31 days	AAACTGCTTCCGGAGCCACCTGG	PLCG1	ENSG00000124181	-0.5071266499779722	[298]	[126,28,NaN]	-5	hSpCas9	negative selection	9907405
41162626	41162649	20	+	27869803	PATU8988S	viability after 31 days	GCTCTATACCATGCAGGACCTGG	PLCG1	ENSG00000124181	0.42047169417809094	[421]	[255,185,NaN]	5	hSpCas9	negative selection	9907406
41162966	41162989	20	-	27869803	PATU8988S	viability after 31 days	GAGTACTGGCTTCCAAGAAGGGG	PLCG1	ENSG00000124181	0.4328005089195462	[677]	[411,304,NaN]	5	hSpCas9	negative selection	9907407
41163252	41163275	20	+	27869803	PATU8988S	viability after 31 days	CAGTTCCTTCTTGACTACCAGGG	PLCG1	ENSG00000124181	0.4353488727855675	[507]	[232,325,NaN]	5	hSpCas9	negative selection	9907408
41137833	41137856	20	+	27869803	HPAFII	viability after 35 days	GGGCGCCGACAAGATCGAGGGGG	PLCG1	ENSG00000124181	-0.841936854179147	[256]	[65,79,NaN]	-5	hSpCas9	negative selection	9989852
41159618	41159641	20	+	27869803	HPAFII	viability after 35 days	AAATTAAGGAGATCCGCCCAGGG	PLCG1	ENSG00000124181	-1.5015472186475787	[97]	[1,34,NaN]	-7	hSpCas9	negative selection	9989853
41160102	41160125	20	-	27869803	HPAFII	viability after 35 days	AAACTGCTTCCGGAGCCACCTGG	PLCG1	ENSG00000124181	1.4511395094183093	[88]	[157,83,NaN]	8	hSpCas9	negative selection	9989854
41162626	41162649	20	+	27869803	HPAFII	viability after 35 days	GCTCTATACCATGCAGGACCTGG	PLCG1	ENSG00000124181	0.829591470489826	[253]	[212,245,NaN]	5	hSpCas9	negative selection	9989855
41162966	41162989	20	-	27869803	HPAFII	viability after 35 days	GAGTACTGGCTTCCAAGAAGGGG	PLCG1	ENSG00000124181	0.4792631417868872	[249]	[214,132,NaN]	3	hSpCas9	negative selection	9989856
41163252	41163275	20	+	27869803	HPAFII	viability after 35 days	CAGTTCCTTCTTGACTACCAGGG	PLCG1	ENSG00000124181	-0.15252726954717902	[216]	[119,74,NaN]	-1	hSpCas9	negative selection	9989857
41137833	41137856	20	+	27869803	HPAFII	viability after 31 days	GGGCGCCGACAAGATCGAGGGGG	PLCG1	ENSG00000124181	-0.6277856270255235	[256]	[33,157,NaN]	-4	hSpCas9	negative selection	10072301
41159618	41159641	20	+	27869803	HPAFII	viability after 31 days	AAATTAAGGAGATCCGCCCAGGG	PLCG1	ENSG00000124181	-0.276264360246941	[97]	[9,83,NaN]	-2	hSpCas9	negative selection	10072302
41160102	41160125	20	-	27869803	HPAFII	viability after 31 days	AAACTGCTTCCGGAGCCACCTGG	PLCG1	ENSG00000124181	1.5630470394577525	[88]	[182,108,NaN]	9	hSpCas9	negative selection	10072303
41162626	41162649	20	+	27869803	HPAFII	viability after 31 days	GCTCTATACCATGCAGGACCTGG	PLCG1	ENSG00000124181	0.9159190066368238	[253]	[267,269,NaN]	6	hSpCas9	negative selection	10072304
41162966	41162989	20	-	27869803	HPAFII	viability after 31 days	GAGTACTGGCTTCCAAGAAGGGG	PLCG1	ENSG00000124181	0.22934274402214752	[249]	[163,164,NaN]	1	hSpCas9	negative selection	10072305
41163252	41163275	20	+	27869803	HPAFII	viability after 31 days	CAGTTCCTTCTTGACTACCAGGG	PLCG1	ENSG00000124181	0.027760418520257096	[216]	[160,83,NaN]	0	hSpCas9	negative selection	10072306
41172200	41172223	20	+	28162770	P31FUJ	viability	AAGGGAAGATAATGGAACGGAGG	PLCG1	ENSG00000124181	-0.23280220441437863	[291]	[291]	-2	hSpCas9	negative selection	10212466
41166811	41166834	20	+	28162770	P31FUJ	viability	GCTGCGCTATCCCATCAACGAGG	PLCG1	ENSG00000124181	0.18223529486446538	[146]	[195]	2	hSpCas9	negative selection	10212467
41137739	41137762	20	-	28162770	P31FUJ	viability	GGAGTAGAACAAAGTCATGACGG	PLCG1	ENSG00000124181	-0.5923445911015188	[203]	[158]	-5	hSpCas9	negative selection	10212468
41159617	41159640	20	+	28162770	P31FUJ	viability	GAAATTAAGGAGATCCGCCCAGG	PLCG1	ENSG00000124181	0.5501495950260078	[246]	[424]	6	hSpCas9	negative selection	10212469
41162670	41162693	20	-	28162770	P31FUJ	viability	CAGCTGAGCAAACTGCCCGTAGG	PLCG1	ENSG00000124181	0.24374968407716913	[395]	[550]	2	hSpCas9	negative selection	10212470
41162963	41162986	20	-	28162770	P31FUJ	viability	TACTGGCTTCCAAGAAGGGGAGG	PLCG1	ENSG00000124181	0.138291947276868	[74]	[96]	1	hSpCas9	negative selection	10212471
41163235	41163258	20	-	28162770	P31FUJ	viability	GAACTGCTGGAACTCAGGAAGGG	PLCG1	ENSG00000124181	0.07498170815271393	[163]	[202]	0	hSpCas9	negative selection	10212472
41165020	41165043	20	+	28162770	P31FUJ	viability	CACACTCCTCACCAAGCCCGTGG	PLCG1	ENSG00000124181	0.535024353456588	[147]	[251]	6	hSpCas9	negative selection	10212473
41165259	41165282	20	+	28162770	P31FUJ	viability	TGAGGGCAGTGCCTACGAGGAGG	PLCG1	ENSG00000124181	-0.26278136190724843	[388]	[380]	-3	hSpCas9	negative selection	10212474
41165530	41165553	20	+	28162770	P31FUJ	viability	GGATGAGGAGGAGCCCAAGGAGG	PLCG1	ENSG00000124181	-1.9208581980996384	[86]	[26]	-8	hSpCas9	negative selection	10212475
41172200	41172223	20	+	28162770	TF1	viability	AAGGGAAGATAATGGAACGGAGG	PLCG1	ENSG00000124181	NaN	[NaN]	[174]	1	hSpCas9	negative selection	10381832
41166811	41166834	20	+	28162770	TF1	viability	GCTGCGCTATCCCATCAACGAGG	PLCG1	ENSG00000124181	NaN	[NaN]	[97]	1	hSpCas9	negative selection	10381833
41137739	41137762	20	-	28162770	TF1	viability	GGAGTAGAACAAAGTCATGACGG	PLCG1	ENSG00000124181	NaN	[NaN]	[285]	1	hSpCas9	negative selection	10381834
41159617	41159640	20	+	28162770	TF1	viability	GAAATTAAGGAGATCCGCCCAGG	PLCG1	ENSG00000124181	NaN	[NaN]	[263]	1	hSpCas9	negative selection	10381835
41162670	41162693	20	-	28162770	TF1	viability	CAGCTGAGCAAACTGCCCGTAGG	PLCG1	ENSG00000124181	NaN	[NaN]	[367]	1	hSpCas9	negative selection	10381836
41162963	41162986	20	-	28162770	TF1	viability	TACTGGCTTCCAAGAAGGGGAGG	PLCG1	ENSG00000124181	NaN	[NaN]	[10]	1	hSpCas9	negative selection	10381837
41163235	41163258	20	-	28162770	TF1	viability	GAACTGCTGGAACTCAGGAAGGG	PLCG1	ENSG00000124181	NaN	[NaN]	[79]	1	hSpCas9	negative selection	10381838
41165020	41165043	20	+	28162770	TF1	viability	CACACTCCTCACCAAGCCCGTGG	PLCG1	ENSG00000124181	NaN	[NaN]	[147]	1	hSpCas9	negative selection	10381839
41165259	41165282	20	+	28162770	TF1	viability	TGAGGGCAGTGCCTACGAGGAGG	PLCG1	ENSG00000124181	NaN	[NaN]	[218]	1	hSpCas9	negative selection	10381840
41165530	41165553	20	+	28162770	TF1	viability	GGATGAGGAGGAGCCCAAGGAGG	PLCG1	ENSG00000124181	NaN	[NaN]	[122]	1	hSpCas9	negative selection	10381841
41172200	41172223	20	+	28162770	SKM1	viability	AAGGGAAGATAATGGAACGGAGG	PLCG1	ENSG00000124181	0.12141477361162678	[64]	[124]	1	hSpCas9	negative selection	10551198
41166811	41166834	20	+	28162770	SKM1	viability	GCTGCGCTATCCCATCAACGAGG	PLCG1	ENSG00000124181	0.1779983019779945	[42]	[85]	1	hSpCas9	negative selection	10551199
41137739	41137762	20	-	28162770	SKM1	viability	GGAGTAGAACAAAGTCATGACGG	PLCG1	ENSG00000124181	-0.3708949440356401	[78]	[107]	-3	hSpCas9	negative selection	10551200
41159617	41159640	20	+	28162770	SKM1	viability	GAAATTAAGGAGATCCGCCCAGG	PLCG1	ENSG00000124181	0.48056107199842557	[89]	[221]	4	hSpCas9	negative selection	10551201
41162670	41162693	20	-	28162770	SKM1	viability	CAGCTGAGCAAACTGCCCGTAGG	PLCG1	ENSG00000124181	0.04167683076521422	[121]	[221]	0	hSpCas9	negative selection	10551202
41162963	41162986	20	-	28162770	SKM1	viability	TACTGGCTTCCAAGAAGGGGAGG	PLCG1	ENSG00000124181	-0.7548875021634687	[20]	[21]	-5	hSpCas9	negative selection	10551203
41163235	41163258	20	-	28162770	SKM1	viability	GAACTGCTGGAACTCAGGAAGGG	PLCG1	ENSG00000124181	-0.5996092766855575	[41]	[48]	-5	hSpCas9	negative selection	10551204
41165020	41165043	20	+	28162770	SKM1	viability	CACACTCCTCACCAAGCCCGTGG	PLCG1	ENSG00000124181	0.14483143804279525	[43]	[85]	1	hSpCas9	negative selection	10551205
41165259	41165282	20	+	28162770	SKM1	viability	TGAGGGCAGTGCCTACGAGGAGG	PLCG1	ENSG00000124181	0.7066925830524055	[60]	[175]	6	hSpCas9	negative selection	10551206
41165530	41165553	20	+	28162770	SKM1	viability	GGATGAGGAGGAGCCCAAGGAGG	PLCG1	ENSG00000124181	-1.1699250014423126	[13]	[10]	-7	hSpCas9	negative selection	10551207
41172200	41172223	20	+	28162770	SKM1	viability	AAGGGAAGATAATGGAACGGAGG	PLCG1	ENSG00000124181	0.12141477361162678	[64]	[124]	1	hSpCas9	negative selection	10720564
41166811	41166834	20	+	28162770	SKM1	viability	GCTGCGCTATCCCATCAACGAGG	PLCG1	ENSG00000124181	0.1779983019779945	[42]	[85]	1	hSpCas9	negative selection	10720565
41137739	41137762	20	-	28162770	SKM1	viability	GGAGTAGAACAAAGTCATGACGG	PLCG1	ENSG00000124181	-0.3708949440356401	[78]	[107]	-3	hSpCas9	negative selection	10720566
41159617	41159640	20	+	28162770	SKM1	viability	GAAATTAAGGAGATCCGCCCAGG	PLCG1	ENSG00000124181	0.48056107199842557	[89]	[221]	4	hSpCas9	negative selection	10720567
41162670	41162693	20	-	28162770	SKM1	viability	CAGCTGAGCAAACTGCCCGTAGG	PLCG1	ENSG00000124181	0.04167683076521422	[121]	[221]	0	hSpCas9	negative selection	10720568
41162963	41162986	20	-	28162770	SKM1	viability	TACTGGCTTCCAAGAAGGGGAGG	PLCG1	ENSG00000124181	-0.7548875021634687	[20]	[21]	-5	hSpCas9	negative selection	10720569
41163235	41163258	20	-	28162770	SKM1	viability	GAACTGCTGGAACTCAGGAAGGG	PLCG1	ENSG00000124181	-0.5996092766855575	[41]	[48]	-5	hSpCas9	negative selection	10720570
41165020	41165043	20	+	28162770	SKM1	viability	CACACTCCTCACCAAGCCCGTGG	PLCG1	ENSG00000124181	0.14483143804279525	[43]	[85]	1	hSpCas9	negative selection	10720571
41165259	41165282	20	+	28162770	SKM1	viability	TGAGGGCAGTGCCTACGAGGAGG	PLCG1	ENSG00000124181	0.7066925830524055	[60]	[175]	6	hSpCas9	negative selection	10720572
41165530	41165553	20	+	28162770	SKM1	viability	GGATGAGGAGGAGCCCAAGGAGG	PLCG1	ENSG00000124181	-1.1699250014423126	[13]	[10]	-7	hSpCas9	negative selection	10720573
41172200	41172223	20	+	28162770	PL21	viability	AAGGGAAGATAATGGAACGGAGG	PLCG1	ENSG00000124181	-0.3062130515354695	[249]	[87]	-2	hSpCas9	negative selection	10889930
41166811	41166834	20	+	28162770	PL21	viability	GCTGCGCTATCCCATCAACGAGG	PLCG1	ENSG00000124181	-0.038265124835758835	[150]	[63]	0	hSpCas9	negative selection	10889931
41137739	41137762	20	-	28162770	PL21	viability	GGAGTAGAACAAAGTCATGACGG	PLCG1	ENSG00000124181	0.7051584806058293	[302]	[214]	6	hSpCas9	negative selection	10889932
41159617	41159640	20	+	28162770	PL21	viability	GAAATTAAGGAGATCCGCCCAGG	PLCG1	ENSG00000124181	-0.14821660567568717	[302]	[118]	-1	hSpCas9	negative selection	10889933
41162670	41162693	20	-	28162770	PL21	viability	CAGCTGAGCAAACTGCCCGTAGG	PLCG1	ENSG00000124181	-0.3954701304313446	[543]	[179]	-3	hSpCas9	negative selection	10889934
41162963	41162986	20	-	28162770	PL21	viability	TACTGGCTTCCAAGAAGGGGAGG	PLCG1	ENSG00000124181	0.285869488515204	[48]	[25]	2	hSpCas9	negative selection	10889935
41163235	41163258	20	-	28162770	PL21	viability	GAACTGCTGGAACTCAGGAAGGG	PLCG1	ENSG00000124181	0.5516119849906976	[115]	[73]	5	hSpCas9	negative selection	10889936
41165020	41165043	20	+	28162770	PL21	viability	CACACTCCTCACCAAGCCCGTGG	PLCG1	ENSG00000124181	0.07814909011070947	[110]	[50]	0	hSpCas9	negative selection	10889937
41165259	41165282	20	+	28162770	PL21	viability	TGAGGGCAGTGCCTACGAGGAGG	PLCG1	ENSG00000124181	0.5383083503838937	[211]	[133]	5	hSpCas9	negative selection	10889938
41165530	41165553	20	+	28162770	PL21	viability	GGATGAGGAGGAGCCCAAGGAGG	PLCG1	ENSG00000124181	0.11267677323898062	[67]	[31]	1	hSpCas9	negative selection	10889939
41172200	41172223	20	+	28162770	P31FUJ	viability	AAGGGAAGATAATGGAACGGAGG	PLCG1	ENSG00000124181	-0.23280220441437863	[291]	[291]	-2	hSpCas9	negative selection	11059296
41166811	41166834	20	+	28162770	P31FUJ	viability	GCTGCGCTATCCCATCAACGAGG	PLCG1	ENSG00000124181	0.18223529486446538	[146]	[195]	2	hSpCas9	negative selection	11059297
41137739	41137762	20	-	28162770	P31FUJ	viability	GGAGTAGAACAAAGTCATGACGG	PLCG1	ENSG00000124181	-0.5923445911015188	[203]	[158]	-5	hSpCas9	negative selection	11059298
41159617	41159640	20	+	28162770	P31FUJ	viability	GAAATTAAGGAGATCCGCCCAGG	PLCG1	ENSG00000124181	0.5501495950260078	[246]	[424]	6	hSpCas9	negative selection	11059299
41162670	41162693	20	-	28162770	P31FUJ	viability	CAGCTGAGCAAACTGCCCGTAGG	PLCG1	ENSG00000124181	0.24374968407716913	[395]	[550]	2	hSpCas9	negative selection	11059300
41162963	41162986	20	-	28162770	P31FUJ	viability	TACTGGCTTCCAAGAAGGGGAGG	PLCG1	ENSG00000124181	0.138291947276868	[74]	[96]	1	hSpCas9	negative selection	11059301
41163235	41163258	20	-	28162770	P31FUJ	viability	GAACTGCTGGAACTCAGGAAGGG	PLCG1	ENSG00000124181	0.07498170815271393	[163]	[202]	0	hSpCas9	negative selection	11059302
41165020	41165043	20	+	28162770	P31FUJ	viability	CACACTCCTCACCAAGCCCGTGG	PLCG1	ENSG00000124181	0.535024353456588	[147]	[251]	6	hSpCas9	negative selection	11059303
41165259	41165282	20	+	28162770	P31FUJ	viability	TGAGGGCAGTGCCTACGAGGAGG	PLCG1	ENSG00000124181	-0.26278136190724843	[388]	[380]	-3	hSpCas9	negative selection	11059304
41165530	41165553	20	+	28162770	P31FUJ	viability	GGATGAGGAGGAGCCCAAGGAGG	PLCG1	ENSG00000124181	-1.9208581980996384	[86]	[26]	-8	hSpCas9	negative selection	11059305
41172200	41172223	20	+	28162770	OCIAML5	viability	AAGGGAAGATAATGGAACGGAGG	PLCG1	ENSG00000124181	0.16979286309974248	[130]	[265]	1	hSpCas9	negative selection	11228662
41166811	41166834	20	+	28162770	OCIAML5	viability	GCTGCGCTATCCCATCAACGAGG	PLCG1	ENSG00000124181	-0.20275365873278323	[94]	[148]	-1	hSpCas9	negative selection	11228663
41137739	41137762	20	-	28162770	OCIAML5	viability	GGAGTAGAACAAAGTCATGACGG	PLCG1	ENSG00000124181	0.5541161305287051	[142]	[378]	5	hSpCas9	negative selection	11228664
41159617	41159640	20	+	28162770	OCIAML5	viability	GAAATTAAGGAGATCCGCCCAGG	PLCG1	ENSG00000124181	0.027181269675392722	[136]	[251]	0	hSpCas9	negative selection	11228665
41162670	41162693	20	-	28162770	OCIAML5	viability	CAGCTGAGCAAACTGCCCGTAGG	PLCG1	ENSG00000124181	0.8053317659838908	[122]	[387]	7	hSpCas9	negative selection	11228666
41162963	41162986	20	-	28162770	OCIAML5	viability	TACTGGCTTCCAAGAAGGGGAGG	PLCG1	ENSG00000124181	0.5234425642282095	[36]	[95]	4	hSpCas9	negative selection	11228667
41163235	41163258	20	-	28162770	OCIAML5	viability	GAACTGCTGGAACTCAGGAAGGG	PLCG1	ENSG00000124181	-1.254825740364404	[77]	[58]	-6	hSpCas9	negative selection	11228668
41165020	41165043	20	+	28162770	OCIAML5	viability	CACACTCCTCACCAAGCCCGTGG	PLCG1	ENSG00000124181	0.4484425403884599	[94]	[233]	4	hSpCas9	negative selection	11228669
41165259	41165282	20	+	28162770	OCIAML5	viability	TGAGGGCAGTGCCTACGAGGAGG	PLCG1	ENSG00000124181	0.6044475643910061	[179]	[493]	5	hSpCas9	negative selection	11228670
41165530	41165553	20	+	28162770	OCIAML5	viability	GGATGAGGAGGAGCCCAAGGAGG	PLCG1	ENSG00000124181	-5.333193260600614	[66]	[2]	-9	hSpCas9	negative selection	11228671
41172200	41172223	20	+	28162770	EOL1	viability	AAGGGAAGATAATGGAACGGAGG	PLCG1	ENSG00000124181	-0.4298401955759037	[426]	[166]	-3	hSpCas9	negative selection	11398028
41166811	41166834	20	+	28162770	EOL1	viability	GCTGCGCTATCCCATCAACGAGG	PLCG1	ENSG00000124181	-0.21122900745993234	[166]	[75]	-2	hSpCas9	negative selection	11398029
41137739	41137762	20	-	28162770	EOL1	viability	GGAGTAGAACAAAGTCATGACGG	PLCG1	ENSG00000124181	0.0587130098952473	[471]	[258]	0	hSpCas9	negative selection	11398030
41159617	41159640	20	+	28162770	EOL1	viability	GAAATTAAGGAGATCCGCCCAGG	PLCG1	ENSG00000124181	-0.31853704491901447	[631]	[266]	-2	hSpCas9	negative selection	11398031
41162670	41162693	20	-	28162770	EOL1	viability	CAGCTGAGCAAACTGCCCGTAGG	PLCG1	ENSG00000124181	0.964504552995922	[818]	[841]	8	hSpCas9	negative selection	11398032
41162963	41162986	20	-	28162770	EOL1	viability	TACTGGCTTCCAAGAAGGGGAGG	PLCG1	ENSG00000124181	0.9443110263919645	[144]	[146]	7	hSpCas9	negative selection	11398033
41163235	41163258	20	-	28162770	EOL1	viability	GAACTGCTGGAACTCAGGAAGGG	PLCG1	ENSG00000124181	-0.6604147291506217	[98]	[32]	-5	hSpCas9	negative selection	11398034
41165020	41165043	20	+	28162770	EOL1	viability	CACACTCCTCACCAAGCCCGTGG	PLCG1	ENSG00000124181	0.43912094440029276	[195]	[139]	4	hSpCas9	negative selection	11398035
41165259	41165282	20	+	28162770	EOL1	viability	TGAGGGCAGTGCCTACGAGGAGG	PLCG1	ENSG00000124181	1.4694945934438117	[328]	[479]	9	hSpCas9	negative selection	11398036
41165530	41165553	20	+	28162770	EOL1	viability	GGATGAGGAGGAGCCCAAGGAGG	PLCG1	ENSG00000124181	-0.41530223131409016	[80]	[31]	-3	hSpCas9	negative selection	11398037
41172200	41172223	20	+	28162770	MOLM13	viability	AAGGGAAGATAATGGAACGGAGG	PLCG1	ENSG00000124181	0.3022517385053647	[377]	[336]	2	hSpCas9	negative selection	11567394
41166811	41166834	20	+	28162770	MOLM13	viability	GCTGCGCTATCCCATCAACGAGG	PLCG1	ENSG00000124181	-0.3086723869674225	[196]	[114]	-2	hSpCas9	negative selection	11567395
41137739	41137762	20	-	28162770	MOLM13	viability	GGAGTAGAACAAAGTCATGACGG	PLCG1	ENSG00000124181	-0.2464156152104553	[378]	[230]	-1	hSpCas9	negative selection	11567396
41159617	41159640	20	+	28162770	MOLM13	viability	GAAATTAAGGAGATCCGCCCAGG	PLCG1	ENSG00000124181	0.3429026047060486	[481]	[441]	2	hSpCas9	negative selection	11567397
41162670	41162693	20	-	28162770	MOLM13	viability	CAGCTGAGCAAACTGCCCGTAGG	PLCG1	ENSG00000124181	0.6928695973701824	[556]	[650]	5	hSpCas9	negative selection	11567398
41162963	41162986	20	-	28162770	MOLM13	viability	TACTGGCTTCCAAGAAGGGGAGG	PLCG1	ENSG00000124181	1.0161934116868871	[92]	[135]	7	hSpCas9	negative selection	11567399
41163235	41163258	20	-	28162770	MOLM13	viability	GAACTGCTGGAACTCAGGAAGGG	PLCG1	ENSG00000124181	0.2013744069758232	[165]	[137]	1	hSpCas9	negative selection	11567400
41165020	41165043	20	+	28162770	MOLM13	viability	CACACTCCTCACCAAGCCCGTGG	PLCG1	ENSG00000124181	0.6405914676574649	[172]	[194]	5	hSpCas9	negative selection	11567401
41165259	41165282	20	+	28162770	MOLM13	viability	TGAGGGCAGTGCCTACGAGGAGG	PLCG1	ENSG00000124181	0.9539276497245615	[336]	[471]	7	hSpCas9	negative selection	11567402
41165530	41165553	20	+	28162770	MOLM13	viability	GGATGAGGAGGAGCCCAAGGAGG	PLCG1	ENSG00000124181	-3.2509288659113675	[78]	[5]	-8	hSpCas9	negative selection	11567403
41172200	41172223	20	+	28162770	HEL	viability	AAGGGAAGATAATGGAACGGAGG	PLCG1	ENSG00000124181	-0.29510469193707367	[317]	[165]	-2	hSpCas9	negative selection	11736760
41166811	41166834	20	+	28162770	HEL	viability	GCTGCGCTATCCCATCAACGAGG	PLCG1	ENSG00000124181	-0.13486874666319504	[131]	[76]	-1	hSpCas9	negative selection	11736761
41137739	41137762	20	-	28162770	HEL	viability	GGAGTAGAACAAAGTCATGACGG	PLCG1	ENSG00000124181	0.390511181123146	[398]	[334]	3	hSpCas9	negative selection	11736762
41159617	41159640	20	+	28162770	HEL	viability	GAAATTAAGGAGATCCGCCCAGG	PLCG1	ENSG00000124181	0.3779756122498121	[333]	[277]	3	hSpCas9	negative selection	11736763
41162670	41162693	20	-	28162770	HEL	viability	CAGCTGAGCAAACTGCCCGTAGG	PLCG1	ENSG00000124181	-0.0749788775725706	[545]	[331]	0	hSpCas9	negative selection	11736764
41162963	41162986	20	-	28162770	HEL	viability	TACTGGCTTCCAAGAAGGGGAGG	PLCG1	ENSG00000124181	-1.1445318440139147	[106]	[30]	-6	hSpCas9	negative selection	11736765
41163235	41163258	20	-	28162770	HEL	viability	GAACTGCTGGAACTCAGGAAGGG	PLCG1	ENSG00000124181	0.5033357753349406	[151]	[137]	4	hSpCas9	negative selection	11736766
41165020	41165043	20	+	28162770	HEL	viability	CACACTCCTCACCAAGCCCGTGG	PLCG1	ENSG00000124181	-0.41837268230303004	[216]	[103]	-3	hSpCas9	negative selection	11736767
41165259	41165282	20	+	28162770	HEL	viability	TGAGGGCAGTGCCTACGAGGAGG	PLCG1	ENSG00000124181	0.3497323464155043	[320]	[261]	3	hSpCas9	negative selection	11736768
41165530	41165553	20	+	28162770	HEL	viability	GGATGAGGAGGAGCCCAAGGAGG	PLCG1	ENSG00000124181	-1.299158213436075	[72]	[18]	-6	hSpCas9	negative selection	11736769
41172200	41172223	20	+	28162770	MV411	viability	AAGGGAAGATAATGGAACGGAGG	PLCG1	ENSG00000124181	0.26499592216708	[244]	[247]	2	hSpCas9	negative selection	11906126
41166811	41166834	20	+	28162770	MV411	viability	GCTGCGCTATCCCATCAACGAGG	PLCG1	ENSG00000124181	1.7187432697083644	[109]	[304]	9	hSpCas9	negative selection	11906127
41137739	41137762	20	-	28162770	MV411	viability	GGAGTAGAACAAAGTCATGACGG	PLCG1	ENSG00000124181	-0.0844060129696699	[218]	[173]	0	hSpCas9	negative selection	11906128
41159617	41159640	20	+	28162770	MV411	viability	GAAATTAAGGAGATCCGCCCAGG	PLCG1	ENSG00000124181	-0.5894266134375513	[283]	[158]	-4	hSpCas9	negative selection	11906129
41162670	41162693	20	-	28162770	MV411	viability	CAGCTGAGCAAACTGCCCGTAGG	PLCG1	ENSG00000124181	0.3793492262883562	[469]	[514]	3	hSpCas9	negative selection	11906130
41162963	41162986	20	-	28162770	MV411	viability	TACTGGCTTCCAAGAAGGGGAGG	PLCG1	ENSG00000124181	2.119789727686815	[61]	[226]	9	hSpCas9	negative selection	11906131
41163235	41163258	20	-	28162770	MV411	viability	GAACTGCTGGAACTCAGGAAGGG	PLCG1	ENSG00000124181	1.2590255250579871	[61]	[124]	9	hSpCas9	negative selection	11906132
41165020	41165043	20	+	28162770	MV411	viability	CACACTCCTCACCAAGCCCGTGG	PLCG1	ENSG00000124181	-0.15628463526823422	[126]	[95]	-1	hSpCas9	negative selection	11906133
41165259	41165282	20	+	28162770	MV411	viability	TGAGGGCAGTGCCTACGAGGAGG	PLCG1	ENSG00000124181	0.4056192191569497	[232]	[259]	3	hSpCas9	negative selection	11906134
41165530	41165553	20	+	28162770	MV411	viability	GGATGAGGAGGAGCCCAAGGAGG	PLCG1	ENSG00000124181	-2.3132774036917034	[58]	[9]	-8	hSpCas9	negative selection	11906135
41172200	41172223	20	+	28162770	MONOMAC1	viability	AAGGGAAGATAATGGAACGGAGG	PLCG1	ENSG00000124181	0.284496064006197	[158]	[221]	3	hSpCas9	negative selection	12075492
41166811	41166834	20	+	28162770	MONOMAC1	viability	GCTGCGCTATCCCATCAACGAGG	PLCG1	ENSG00000124181	-0.1220747893783316	[74]	[78]	-1	hSpCas9	negative selection	12075493
41137739	41137762	20	-	28162770	MONOMAC1	viability	GGAGTAGAACAAAGTCATGACGG	PLCG1	ENSG00000124181	0.5675332085012542	[175]	[298]	5	hSpCas9	negative selection	12075494
41159617	41159640	20	+	28162770	MONOMAC1	viability	GAAATTAAGGAGATCCGCCCAGG	PLCG1	ENSG00000124181	0.40562765539506146	[161]	[245]	4	hSpCas9	negative selection	12075495
41162670	41162693	20	-	28162770	MONOMAC1	viability	CAGCTGAGCAAACTGCCCGTAGG	PLCG1	ENSG00000124181	0.01708795829329368	[274]	[318]	0	hSpCas9	negative selection	12075496
41162963	41162986	20	-	28162770	MONOMAC1	viability	TACTGGCTTCCAAGAAGGGGAGG	PLCG1	ENSG00000124181	-0.4409624299456427	[44]	[37]	-4	hSpCas9	negative selection	12075497
41163235	41163258	20	-	28162770	MONOMAC1	viability	GAACTGCTGGAACTCAGGAAGGG	PLCG1	ENSG00000124181	1.0484391873899357	[61]	[146]	8	hSpCas9	negative selection	12075498
41165020	41165043	20	+	28162770	MONOMAC1	viability	CACACTCCTCACCAAGCCCGTGG	PLCG1	ENSG00000124181	-0.7668924553905017	[94]	[63]	-6	hSpCas9	negative selection	12075499
41165259	41165282	20	+	28162770	MONOMAC1	viability	TGAGGGCAGTGCCTACGAGGAGG	PLCG1	ENSG00000124181	-0.39112389917585616	[142]	[124]	-3	hSpCas9	negative selection	12075500
41165530	41165553	20	+	28162770	MONOMAC1	viability	GGATGAGGAGGAGCCCAAGGAGG	PLCG1	ENSG00000124181	-0.44701510006790124	[43]	[36]	-4	hSpCas9	negative selection	12075501
41172200	41172223	20	+	28162770	OCIAML2	viability	AAGGGAAGATAATGGAACGGAGG	PLCG1	ENSG00000124181	0.45729876013714454	[58]	[448]	4	hSpCas9	negative selection	12244858
41166811	41166834	20	+	28162770	OCIAML2	viability	GCTGCGCTATCCCATCAACGAGG	PLCG1	ENSG00000124181	-0.158685818927421	[28]	[143]	-1	hSpCas9	negative selection	12244859
41137739	41137762	20	-	28162770	OCIAML2	viability	GGAGTAGAACAAAGTCATGACGG	PLCG1	ENSG00000124181	0.4025776441100686	[51]	[380]	4	hSpCas9	negative selection	12244860
41159617	41159640	20	+	28162770	OCIAML2	viability	GAAATTAAGGAGATCCGCCCAGG	PLCG1	ENSG00000124181	0.41334637841835553	[54]	[405]	4	hSpCas9	negative selection	12244861
41162670	41162693	20	-	28162770	OCIAML2	viability	CAGCTGAGCAAACTGCCCGTAGG	PLCG1	ENSG00000124181	0.517297342457264	[74]	[594]	5	hSpCas9	negative selection	12244862
41162963	41162986	20	-	28162770	OCIAML2	viability	TACTGGCTTCCAAGAAGGGGAGG	PLCG1	ENSG00000124181	0.5051226285111615	[14]	[117]	5	hSpCas9	negative selection	12244863
41163235	41163258	20	-	28162770	OCIAML2	viability	GAACTGCTGGAACTCAGGAAGGG	PLCG1	ENSG00000124181	0.17091620384536244	[24]	[155]	1	hSpCas9	negative selection	12244864
41165020	41165043	20	+	28162770	OCIAML2	viability	CACACTCCTCACCAAGCCCGTGG	PLCG1	ENSG00000124181	0.1060174072669913	[28]	[172]	1	hSpCas9	negative selection	12244865
41165259	41165282	20	+	28162770	OCIAML2	viability	TGAGGGCAGTGCCTACGAGGAGG	PLCG1	ENSG00000124181	0.6992951762001511	[43]	[395]	6	hSpCas9	negative selection	12244866
41165530	41165553	20	+	28162770	OCIAML2	viability	GGATGAGGAGGAGCCCAAGGAGG	PLCG1	ENSG00000124181	-1.5775450291586735	[6]	[12]	-7	hSpCas9	negative selection	12244867
41172200	41172223	20	+	28162770	OCIAML3	viability	AAGGGAAGATAATGGAACGGAGG	PLCG1	ENSG00000124181	-0.49212802630494956	[81]	[175]	-4	hSpCas9	negative selection	12414224
41166811	41166834	20	+	28162770	OCIAML3	viability	GCTGCGCTATCCCATCAACGAGG	PLCG1	ENSG00000124181	-0.26216407657171814	[28]	[72]	-2	hSpCas9	negative selection	12414225
41137739	41137762	20	-	28162770	OCIAML3	viability	GGAGTAGAACAAAGTCATGACGG	PLCG1	ENSG00000124181	0.070682052867727	[87]	[278]	0	hSpCas9	negative selection	12414226
41159617	41159640	20	+	28162770	OCIAML3	viability	GAAATTAAGGAGATCCGCCCAGG	PLCG1	ENSG00000124181	0.5098281706603769	[66]	[287]	5	hSpCas9	negative selection	12414227
41162670	41162693	20	-	28162770	OCIAML3	viability	CAGCTGAGCAAACTGCCCGTAGG	PLCG1	ENSG00000124181	0.7019771873109174	[100]	[495]	6	hSpCas9	negative selection	12414228
41162963	41162986	20	-	28162770	OCIAML3	viability	TACTGGCTTCCAAGAAGGGGAGG	PLCG1	ENSG00000124181	-0.5615861626317857	[21]	[44]	-4	hSpCas9	negative selection	12414229
41163235	41163258	20	-	28162770	OCIAML3	viability	GAACTGCTGGAACTCAGGAAGGG	PLCG1	ENSG00000124181	-0.8965704103445944	[36]	[59]	-6	hSpCas9	negative selection	12414230
41165020	41165043	20	+	28162770	OCIAML3	viability	CACACTCCTCACCAAGCCCGTGG	PLCG1	ENSG00000124181	-0.8715416158530722	[39]	[65]	-6	hSpCas9	negative selection	12414231
41165259	41165282	20	+	28162770	OCIAML3	viability	TGAGGGCAGTGCCTACGAGGAGG	PLCG1	ENSG00000124181	-0.20555492663628072	[88]	[232]	-2	hSpCas9	negative selection	12414232
41165530	41165553	20	+	28162770	OCIAML3	viability	GGATGAGGAGGAGCCCAAGGAGG	PLCG1	ENSG00000124181	-2.246084336903856	[10]	[6]	-8	hSpCas9	negative selection	12414233