Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:26499
• Symbol:PLEK2
• Description:pleckstrin 2

DataSource: http://genomecrispr.dkfz.de/#!/results/PLEK2

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
67397719	67397742	14	-	26472758	Jiyoye	viability	GAGTGACCCCTCCCAAGGGCCGG	PLEK2	ENSG00000100558	1.072308230911013	[69]	[110]	7	hSpCas9	negative selection	122019
67412017	67412040	14	-	26472758	Jiyoye	viability	GGAGGGCTTCCTGGTCAAGAGGG	PLEK2	ENSG00000100558	-0.6708271304953997	[151]	[71]	-5	hSpCas9	negative selection	122020
67392824	67392847	14	+	26472758	Jiyoye	viability	GATGAGCCAGTCCACCAGGGAGG	PLEK2	ENSG00000100558	0.49753940915853767	[262]	[279]	4	hSpCas9	negative selection	122021
67412049	67412072	14	-	26472758	Jiyoye	viability	GCGGGCGGCGACATGGAGGACGG	PLEK2	ENSG00000100558	0.9526095180403924	[36]	[53]	6	hSpCas9	negative selection	122022
67412035	67412058	14	-	26472758	Jiyoye	viability	GGAGGACGGCGTGCTCAAGGAGG	PLEK2	ENSG00000100558	0.1264389739386208	[163]	[134]	1	hSpCas9	negative selection	122023
67397712	67397735	14	+	26472758	Jiyoye	viability	GGAGGATCCGGCCCTTGGGAGGG	PLEK2	ENSG00000100558	-0.01190895083567245	[356]	[266]	0	hSpCas9	negative selection	122024
67395533	67395556	14	+	26472758	Jiyoye	viability	GGCCTCCAGGAAGTACTCCGTGG	PLEK2	ENSG00000100558	-0.26311917301504495	[147]	[92]	-2	hSpCas9	negative selection	122025
67392352	67392375	14	-	26472758	Jiyoye	viability	TGTGGAGTTAAGTGGCACGGTGG	PLEK2	ENSG00000100558	-0.8461110477763583	[235]	[98]	-5	hSpCas9	negative selection	122026
67390698	67390721	14	-	26472758	Jiyoye	viability	GCGTCGCTTTGTTCTAAGGAAGG	PLEK2	ENSG00000100558	-0.29144390101085005	[98]	[60]	-2	hSpCas9	negative selection	122027
67388284	67388307	14	-	26472758	Jiyoye	viability	ACAGGAAGAGAACAGGCCAGTGG	PLEK2	ENSG00000100558	0.9127034147326246	[223]	[317]	6	hSpCas9	negative selection	122028
67397719	67397742	14	-	26472758	KBM7	viability	GAGTGACCCCTCCCAAGGGCCGG	PLEK2	ENSG00000100558	0.31388829837831544	[329,257]	[122,212]	3	hSpCas9	negative selection	313137
67412017	67412040	14	-	26472758	KBM7	viability	GGAGGGCTTCCTGGTCAAGAGGG	PLEK2	ENSG00000100558	0.8361061440563643	[612,427]	[504,364]	8	hSpCas9	negative selection	313138
67392824	67392847	14	+	26472758	KBM7	viability	GATGAGCCAGTCCACCAGGGAGG	PLEK2	ENSG00000100558	0.3035424135694651	[854,741]	[428,491]	3	hSpCas9	negative selection	313139
67412049	67412072	14	-	26472758	KBM7	viability	GCGGGCGGCGACATGGAGGACGG	PLEK2	ENSG00000100558	-0.09887201166565385	[168,151]	[118,26]	-1	hSpCas9	negative selection	313140
67412035	67412058	14	-	26472758	KBM7	viability	GGAGGACGGCGTGCTCAAGGAGG	PLEK2	ENSG00000100558	0.25328757432578075	[772,605]	[524,256]	2	hSpCas9	negative selection	313141
67397712	67397735	14	+	26472758	KBM7	viability	GGAGGATCCGGCCCTTGGGAGGG	PLEK2	ENSG00000100558	-0.2587561428095476	[1186,639]	[363,336]	-2	hSpCas9	negative selection	313142
67395533	67395556	14	+	26472758	KBM7	viability	GGCCTCCAGGAAGTACTCCGTGG	PLEK2	ENSG00000100558	0.3713529948092465	[615,511]	[275,399]	4	hSpCas9	negative selection	313143
67392352	67392375	14	-	26472758	KBM7	viability	TGTGGAGTTAAGTGGCACGGTGG	PLEK2	ENSG00000100558	1.1983665020383834	[816,552]	[517,915]	9	hSpCas9	negative selection	313144
67390698	67390721	14	-	26472758	KBM7	viability	GCGTCGCTTTGTTCTAAGGAAGG	PLEK2	ENSG00000100558	0.017417860863785606	[550,347]	[322,108]	0	hSpCas9	negative selection	313145
67388284	67388307	14	-	26472758	KBM7	viability	ACAGGAAGAGAACAGGCCAGTGG	PLEK2	ENSG00000100558	-0.23328193572511058	[1445,1251]	[495,575]	-2	hSpCas9	negative selection	313146
67397719	67397742	14	-	26472758	Raji	viability	GAGTGACCCCTCCCAAGGGCCGG	PLEK2	ENSG00000100558	0.857405282365252	[87]	[36]	7	hSpCas9	negative selection	504255
67412017	67412040	14	-	26472758	Raji	viability	GGAGGGCTTCCTGGTCAAGAGGG	PLEK2	ENSG00000100558	0.43336984683531515	[283]	[88]	4	hSpCas9	negative selection	504256
67392824	67392847	14	+	26472758	Raji	viability	GATGAGCCAGTCCACCAGGGAGG	PLEK2	ENSG00000100558	0.37581119997761203	[444]	[133]	3	hSpCas9	negative selection	504257
67412049	67412072	14	-	26472758	Raji	viability	GCGGGCGGCGACATGGAGGACGG	PLEK2	ENSG00000100558	1.4635273455988747	[74]	[47]	9	hSpCas9	negative selection	504258
67412035	67412058	14	-	26472758	Raji	viability	GGAGGACGGCGTGCTCAAGGAGG	PLEK2	ENSG00000100558	-0.48357770596899974	[240]	[39]	-4	hSpCas9	negative selection	504259
67397712	67397735	14	+	26472758	Raji	viability	GGAGGATCCGGCCCTTGGGAGGG	PLEK2	ENSG00000100558	-0.367525419882643	[655]	[117]	-3	hSpCas9	negative selection	504260
67395533	67395556	14	+	26472758	Raji	viability	GGCCTCCAGGAAGTACTCCGTGG	PLEK2	ENSG00000100558	0.33319547725119475	[300]	[87]	3	hSpCas9	negative selection	504261
67392352	67392375	14	-	26472758	Raji	viability	TGTGGAGTTAAGTGGCACGGTGG	PLEK2	ENSG00000100558	0.27836973218622235	[301]	[84]	2	hSpCas9	negative selection	504262
67390698	67390721	14	-	26472758	Raji	viability	GCGTCGCTTTGTTCTAAGGAAGG	PLEK2	ENSG00000100558	0.6792898832693093	[147]	[54]	6	hSpCas9	negative selection	504263
67388284	67388307	14	-	26472758	Raji	viability	ACAGGAAGAGAACAGGCCAGTGG	PLEK2	ENSG00000100558	-0.4517270875028119	[718]	[121]	-4	hSpCas9	negative selection	504264
67397719	67397742	14	-	26472758	K562	viability	GAGTGACCCCTCCCAAGGGCCGG	PLEK2	ENSG00000100558	-0.4048941844647669	[297]	[189]	-3	hSpCas9	negative selection	695373
67412017	67412040	14	-	26472758	K562	viability	GGAGGGCTTCCTGGTCAAGAGGG	PLEK2	ENSG00000100558	-0.6146603880258833	[574]	[316]	-4	hSpCas9	negative selection	695374
67392824	67392847	14	+	26472758	K562	viability	GATGAGCCAGTCCACCAGGGAGG	PLEK2	ENSG00000100558	0.4955701419843188	[893]	[1063]	4	hSpCas9	negative selection	695375
67412049	67412072	14	-	26472758	K562	viability	GCGGGCGGCGACATGGAGGACGG	PLEK2	ENSG00000100558	0.7224660244710912	[223]	[311]	6	hSpCas9	negative selection	695376
67412035	67412058	14	-	26472758	K562	viability	GGAGGACGGCGTGCTCAAGGAGG	PLEK2	ENSG00000100558	0.9218509985230342	[563]	[901]	7	hSpCas9	negative selection	695377
67397712	67397735	14	+	26472758	K562	viability	GGAGGATCCGGCCCTTGGGAGGG	PLEK2	ENSG00000100558	-0.37618815249706183	[880]	[572]	-2	hSpCas9	negative selection	695378
67395533	67395556	14	+	26472758	K562	viability	GGCCTCCAGGAAGTACTCCGTGG	PLEK2	ENSG00000100558	-0.454499962351795	[473]	[291]	-3	hSpCas9	negative selection	695379
67392352	67392375	14	-	26472758	K562	viability	TGTGGAGTTAAGTGGCACGGTGG	PLEK2	ENSG00000100558	0.2833723620110228	[474]	[487]	2	hSpCas9	negative selection	695380
67390698	67390721	14	-	26472758	K562	viability	GCGTCGCTTTGTTCTAAGGAAGG	PLEK2	ENSG00000100558	0.13205636221048905	[346]	[320]	1	hSpCas9	negative selection	695381
67388284	67388307	14	-	26472758	K562	viability	ACAGGAAGAGAACAGGCCAGTGG	PLEK2	ENSG00000100558	0.4603434663707322	[1021]	[1186]	3	hSpCas9	negative selection	695382
67390698	67390721	14	-	26627737	DLD1	viability	GCGTCGCTTTGTTCTAAGGAAGG	PLEK2	ENSG00000100558	0.8783850417431351	[275]	[171,160,144]	8	hSpCas9	negative selection	789082
67392352	67392375	14	-	26627737	DLD1	viability	TGTGGAGTTAAGTGGCACGGTGG	PLEK2	ENSG00000100558	0.5824094041132554	[501]	[169,378,171]	6	hSpCas9	negative selection	789083
67392824	67392847	14	+	26627737	DLD1	viability	GATGAGCCAGTCCACCAGGGAGG	PLEK2	ENSG00000100558	-0.5465782400588635	[408]	[80,30,139]	-5	hSpCas9	negative selection	789084
67393206	67393229	14	-	26627737	DLD1	viability	AAGATGCACGATAGCAACACCGG	PLEK2	ENSG00000100558	-0.13381872988000976	[816]	[330,183,187]	-1	hSpCas9	negative selection	789085
67395466	67395489	14	-	26627737	DLD1	viability	GGCTATTCATGCAGGGCAGCCGG	PLEK2	ENSG00000100558	0.0812736894938497	[375]	[152,130,93]	0	hSpCas9	negative selection	789086
67397712	67397735	14	+	26627737	DLD1	viability	GGAGGATCCGGCCCTTGGGAGGG	PLEK2	ENSG00000100558	0.7030762451007746	[97]	[55,58,36]	7	hSpCas9	negative selection	789087
67390698	67390721	14	-	26627737	GBM cells	viability after 5 days	GCGTCGCTTTGTTCTAAGGAAGG	PLEK2	ENSG00000100558	-0.22863617483482535	[389]	[182,173]	-4	hSpCas9	negative selection	871397
67392352	67392375	14	-	26627737	GBM cells	viability after 5 days	TGTGGAGTTAAGTGGCACGGTGG	PLEK2	ENSG00000100558	-0.8269111616753203	[171]	[50,52]	-8	hSpCas9	negative selection	871398
67392824	67392847	14	+	26627737	GBM cells	viability after 5 days	GATGAGCCAGTCCACCAGGGAGG	PLEK2	ENSG00000100558	-0.051504096263754295	[142]	[79,67]	-1	hSpCas9	negative selection	871399
67393206	67393229	14	-	26627737	GBM cells	viability after 5 days	AAGATGCACGATAGCAACACCGG	PLEK2	ENSG00000100558	-0.3365994681842034	[404]	[158,184]	-5	hSpCas9	negative selection	871400
67395466	67395489	14	-	26627737	GBM cells	viability after 5 days	GGCTATTCATGCAGGGCAGCCGG	PLEK2	ENSG00000100558	-0.13124809562456685	[144]	[72,68]	-2	hSpCas9	negative selection	871401
67397712	67397735	14	+	26627737	GBM cells	viability after 5 days	GGAGGATCCGGCCCTTGGGAGGG	PLEK2	ENSG00000100558	0.24941112196981896	[79]	[47,53]	4	hSpCas9	negative selection	871402
67390698	67390721	14	-	26627737	GBM cells	viability after 13 days	GCGTCGCTTTGTTCTAAGGAAGG	PLEK2	ENSG00000100558	-0.10797581849892324	[389]	[197,194]	-1	hSpCas9	negative selection	953712
67392352	67392375	14	-	26627737	GBM cells	viability after 13 days	TGTGGAGTTAAGTGGCACGGTGG	PLEK2	ENSG00000100558	0.040690364826214076	[171]	[79,108]	0	hSpCas9	negative selection	953713
67392824	67392847	14	+	26627737	GBM cells	viability after 13 days	GATGAGCCAGTCCACCAGGGAGG	PLEK2	ENSG00000100558	0.28705375739502403	[142]	[124,69]	3	hSpCas9	negative selection	953714
67393206	67393229	14	-	26627737	GBM cells	viability after 13 days	AAGATGCACGATAGCAACACCGG	PLEK2	ENSG00000100558	-0.310811390360789	[404]	[212,147]	-4	hSpCas9	negative selection	953715
67395466	67395489	14	-	26627737	GBM cells	viability after 13 days	GGCTATTCATGCAGGGCAGCCGG	PLEK2	ENSG00000100558	-0.22209088328266757	[144]	[67,66]	-3	hSpCas9	negative selection	953716
67397712	67397735	14	+	26627737	GBM cells	viability after 13 days	GGAGGATCCGGCCCTTGGGAGGG	PLEK2	ENSG00000100558	0.4490973053293381	[79]	[93,30]	5	hSpCas9	negative selection	953717
67390698	67390721	14	-	26627737	GBM cells	viability after 21 days	GCGTCGCTTTGTTCTAAGGAAGG	PLEK2	ENSG00000100558	-0.030979518479427703	[389]	[221,193]	0	hSpCas9	negative selection	1036027
67392352	67392375	14	-	26627737	GBM cells	viability after 21 days	TGTGGAGTTAAGTGGCACGGTGG	PLEK2	ENSG00000100558	0.08946498964300448	[171]	[112,86]	0	hSpCas9	negative selection	1036028
67392824	67392847	14	+	26627737	GBM cells	viability after 21 days	GATGAGCCAGTCCACCAGGGAGG	PLEK2	ENSG00000100558	-0.9513121710772181	[142]	[35,43]	-7	hSpCas9	negative selection	1036029
67393206	67393229	14	-	26627737	GBM cells	viability after 21 days	AAGATGCACGATAGCAACACCGG	PLEK2	ENSG00000100558	-0.03813156172914345	[404]	[230,198]	0	hSpCas9	negative selection	1036030
67395466	67395489	14	-	26627737	GBM cells	viability after 21 days	GGCTATTCATGCAGGGCAGCCGG	PLEK2	ENSG00000100558	-0.2124487028941935	[144]	[79,56]	-2	hSpCas9	negative selection	1036031
67397712	67397735	14	+	26627737	GBM cells	viability after 21 days	GGAGGATCCGGCCCTTGGGAGGG	PLEK2	ENSG00000100558	-0.3992450091467481	[79]	[33,31]	-4	hSpCas9	negative selection	1036032
67390698	67390721	14	-	26627737	RPE1	viability after 9 days	GCGTCGCTTTGTTCTAAGGAAGG	PLEK2	ENSG00000100558	-0.059641583738685	[1369]	[366,468]	0	hSpCas9	negative selection	1118342
67392352	67392375	14	-	26627737	RPE1	viability after 9 days	TGTGGAGTTAAGTGGCACGGTGG	PLEK2	ENSG00000100558	0.4835894165133219	[754]	[326,334]	3	hSpCas9	negative selection	1118343
67392824	67392847	14	+	26627737	RPE1	viability after 9 days	GATGAGCCAGTCCACCAGGGAGG	PLEK2	ENSG00000100558	0.549631429348858	[311]	[66,240]	4	hSpCas9	negative selection	1118344
67393206	67393229	14	-	26627737	RPE1	viability after 9 days	AAGATGCACGATAGCAACACCGG	PLEK2	ENSG00000100558	-0.3802356361198166	[1243]	[286,314]	-3	hSpCas9	negative selection	1118345
67395466	67395489	14	-	26627737	RPE1	viability after 9 days	GGCTATTCATGCAGGGCAGCCGG	PLEK2	ENSG00000100558	-0.015399340648933224	[370]	[10,248]	0	hSpCas9	negative selection	1118346
67397712	67397735	14	+	26627737	RPE1	viability after 9 days	GGAGGATCCGGCCCTTGGGAGGG	PLEK2	ENSG00000100558	0.06535854966408494	[216]	[50,96]	0	hSpCas9	negative selection	1118347
67390698	67390721	14	-	26627737	RPE1	viability after 12 days	GCGTCGCTTTGTTCTAAGGAAGG	PLEK2	ENSG00000100558	0.2060147123062409	[1369]	[358,493]	1	hSpCas9	negative selection	1200657
67392352	67392375	14	-	26627737	RPE1	viability after 12 days	TGTGGAGTTAAGTGGCACGGTGG	PLEK2	ENSG00000100558	-0.1083176428889223	[754]	[227,145]	0	hSpCas9	negative selection	1200658
67392824	67392847	14	+	26627737	RPE1	viability after 12 days	GATGAGCCAGTCCACCAGGGAGG	PLEK2	ENSG00000100558	-0.3330788999232106	[311]	[33,100]	-2	hSpCas9	negative selection	1200659
67393206	67393229	14	-	26627737	RPE1	viability after 12 days	AAGATGCACGATAGCAACACCGG	PLEK2	ENSG00000100558	-0.4470123065383341	[1243]	[233,256]	-3	hSpCas9	negative selection	1200660
67395466	67395489	14	-	26627737	RPE1	viability after 12 days	GGCTATTCATGCAGGGCAGCCGG	PLEK2	ENSG00000100558	0.5926743528421573	[370]	[126,174]	4	hSpCas9	negative selection	1200661
67397712	67397735	14	+	26627737	RPE1	viability after 12 days	GGAGGATCCGGCCCTTGGGAGGG	PLEK2	ENSG00000100558	-0.5455741923408715	[216]	[54,23]	-4	hSpCas9	negative selection	1200662
67390698	67390721	14	-	26627737	RPE1	viability after 15 days	GCGTCGCTTTGTTCTAAGGAAGG	PLEK2	ENSG00000100558	0.3532184710726328	[1369]	[435,551]	2	hSpCas9	negative selection	1282972
67392352	67392375	14	-	26627737	RPE1	viability after 15 days	TGTGGAGTTAAGTGGCACGGTGG	PLEK2	ENSG00000100558	0.4019277578811816	[754]	[355,210]	2	hSpCas9	negative selection	1282973
67392824	67392847	14	+	26627737	RPE1	viability after 15 days	GATGAGCCAGTCCACCAGGGAGG	PLEK2	ENSG00000100558	-0.6386298294146495	[311]	[45,66]	-4	hSpCas9	negative selection	1282974
67393206	67393229	14	-	26627737	RPE1	viability after 15 days	AAGATGCACGATAGCAACACCGG	PLEK2	ENSG00000100558	-0.1968313662982587	[1243]	[333,280]	-1	hSpCas9	negative selection	1282975
67395466	67395489	14	-	26627737	RPE1	viability after 15 days	GGCTATTCATGCAGGGCAGCCGG	PLEK2	ENSG00000100558	0.06275020575473711	[370]	[46,169]	0	hSpCas9	negative selection	1282976
67397712	67397735	14	+	26627737	RPE1	viability after 15 days	GGAGGATCCGGCCCTTGGGAGGG	PLEK2	ENSG00000100558	-1.3266921025812066	[216]	[25,22]	-7	hSpCas9	negative selection	1282977
67390698	67390721	14	-	26627737	RPE1	viability after 18 days	GCGTCGCTTTGTTCTAAGGAAGG	PLEK2	ENSG00000100558	0.07117084601202295	[1369]	[385,390]	0	hSpCas9	negative selection	1365287
67392352	67392375	14	-	26627737	RPE1	viability after 18 days	TGTGGAGTTAAGTGGCACGGTGG	PLEK2	ENSG00000100558	-0.02872413256236954	[754]	[191,207]	0	hSpCas9	negative selection	1365288
67392824	67392847	14	+	26627737	RPE1	viability after 18 days	GATGAGCCAGTCCACCAGGGAGG	PLEK2	ENSG00000100558	-0.42596213817637696	[311]	[23,103]	-3	hSpCas9	negative selection	1365289
67393206	67393229	14	-	26627737	RPE1	viability after 18 days	AAGATGCACGATAGCAACACCGG	PLEK2	ENSG00000100558	-0.11915275783165635	[1243]	[384,227]	0	hSpCas9	negative selection	1365290
67395466	67395489	14	-	26627737	RPE1	viability after 18 days	GGCTATTCATGCAGGGCAGCCGG	PLEK2	ENSG00000100558	0.6889574313661858	[370]	[114,210]	4	hSpCas9	negative selection	1365291
67397712	67397735	14	+	26627737	RPE1	viability after 18 days	GGAGGATCCGGCCCTTGGGAGGG	PLEK2	ENSG00000100558	-1.8301848985526896	[216]	[0,32]	-8	hSpCas9	negative selection	1365292
67390698	67390721	14	-	26627737	HeLa	viability after 8 days	GCGTCGCTTTGTTCTAAGGAAGG	PLEK2	ENSG00000100558	1.0013921075870154	[268]	[242,243,218]	7	hSpCas9	negative selection	1447602
67392352	67392375	14	-	26627737	HeLa	viability after 8 days	TGTGGAGTTAAGTGGCACGGTGG	PLEK2	ENSG00000100558	-0.19998732916541168	[493]	[250,100,220]	-2	hSpCas9	negative selection	1447603
67392824	67392847	14	+	26627737	HeLa	viability after 8 days	GATGAGCCAGTCCACCAGGGAGG	PLEK2	ENSG00000100558	4.213865795625857	[10]	[105,56,105]	9	hSpCas9	negative selection	1447604
67393206	67393229	14	-	26627737	HeLa	viability after 8 days	AAGATGCACGATAGCAACACCGG	PLEK2	ENSG00000100558	-1.4410112751062503	[818]	[214,62,133]	-9	hSpCas9	negative selection	1447605
67395466	67395489	14	-	26627737	HeLa	viability after 8 days	GGCTATTCATGCAGGGCAGCCGG	PLEK2	ENSG00000100558	0.9939460211821136	[152]	[89,144,151]	7	hSpCas9	negative selection	1447606
67397712	67397735	14	+	26627737	HeLa	viability after 8 days	GGAGGATCCGGCCCTTGGGAGGG	PLEK2	ENSG00000100558	0.8411869721242606	[79]	[68,48,69]	7	hSpCas9	negative selection	1447607
67390698	67390721	14	-	26627737	HeLa	viability after 12 days	GCGTCGCTTTGTTCTAAGGAAGG	PLEK2	ENSG00000100558	0.9422154277444896	[268]	[301,188,154]	7	hSpCas9	negative selection	1529917
67392352	67392375	14	-	26627737	HeLa	viability after 12 days	TGTGGAGTTAAGTGGCACGGTGG	PLEK2	ENSG00000100558	-0.6542933703193755	[493]	[108,115,164]	-5	hSpCas9	negative selection	1529918
67392824	67392847	14	+	26627737	HeLa	viability after 12 days	GATGAGCCAGTCCACCAGGGAGG	PLEK2	ENSG00000100558	4.728738350488138	[10]	[148,67,150]	9	hSpCas9	negative selection	1529919
67393206	67393229	14	-	26627737	HeLa	viability after 12 days	AAGATGCACGATAGCAACACCGG	PLEK2	ENSG00000100558	-1.023501526091558	[818]	[272,105,129]	-7	hSpCas9	negative selection	1529920
67395466	67395489	14	-	26627737	HeLa	viability after 12 days	GGCTATTCATGCAGGGCAGCCGG	PLEK2	ENSG00000100558	0.6135938436240685	[152]	[171,62,60]	5	hSpCas9	negative selection	1529921
67397712	67397735	14	+	26627737	HeLa	viability after 12 days	GGAGGATCCGGCCCTTGGGAGGG	PLEK2	ENSG00000100558	1.2693136926839457	[79]	[101,95,39]	8	hSpCas9	negative selection	1529922
67390698	67390721	14	-	26627737	HeLa	viability after 15 days	GCGTCGCTTTGTTCTAAGGAAGG	PLEK2	ENSG00000100558	1.0656946415564552	[268]	[293,209,178]	7	hSpCas9	negative selection	1612232
67392352	67392375	14	-	26627737	HeLa	viability after 15 days	TGTGGAGTTAAGTGGCACGGTGG	PLEK2	ENSG00000100558	-1.3114858383396601	[493]	[116,39,85]	-8	hSpCas9	negative selection	1612233
67392824	67392847	14	+	26627737	HeLa	viability after 15 days	GATGAGCCAGTCCACCAGGGAGG	PLEK2	ENSG00000100558	4.689096295655182	[10]	[235,65,36]	9	hSpCas9	negative selection	1612234
67393206	67393229	14	-	26627737	HeLa	viability after 15 days	AAGATGCACGATAGCAACACCGG	PLEK2	ENSG00000100558	-1.841259047050762	[818]	[194,23,55]	-9	hSpCas9	negative selection	1612235
67395466	67395489	14	-	26627737	HeLa	viability after 15 days	GGCTATTCATGCAGGGCAGCCGG	PLEK2	ENSG00000100558	1.3766690416793517	[152]	[237,38,210]	8	hSpCas9	negative selection	1612236
67397712	67397735	14	+	26627737	HeLa	viability after 15 days	GGAGGATCCGGCCCTTGGGAGGG	PLEK2	ENSG00000100558	1.2012853504388148	[79]	[113,0,111]	8	hSpCas9	negative selection	1612237
67390698	67390721	14	-	26627737	HeLa	viability after 18 days	GCGTCGCTTTGTTCTAAGGAAGG	PLEK2	ENSG00000100558	1.0696599546491483	[268]	[195,176,178]	7	hSpCas9	negative selection	1694547
67392352	67392375	14	-	26627737	HeLa	viability after 18 days	TGTGGAGTTAAGTGGCACGGTGG	PLEK2	ENSG00000100558	-1.3466955852911884	[493]	[73,33,85]	-8	hSpCas9	negative selection	1694548
67392824	67392847	14	+	26627737	HeLa	viability after 18 days	GATGAGCCAGTCCACCAGGGAGG	PLEK2	ENSG00000100558	4.700173018063853	[10]	[158,55,36]	9	hSpCas9	negative selection	1694549
67393206	67393229	14	-	26627737	HeLa	viability after 18 days	AAGATGCACGATAGCAACACCGG	PLEK2	ENSG00000100558	-1.7753295202632429	[818]	[135,23,55]	-9	hSpCas9	negative selection	1694550
67395466	67395489	14	-	26627737	HeLa	viability after 18 days	GGCTATTCATGCAGGGCAGCCGG	PLEK2	ENSG00000100558	1.3142341198788958	[152]	[148,28,210]	8	hSpCas9	negative selection	1694551
67397712	67397735	14	+	26627737	HeLa	viability after 18 days	GGAGGATCCGGCCCTTGGGAGGG	PLEK2	ENSG00000100558	1.2561579437078314	[79]	[81,0,111]	8	hSpCas9	negative selection	1694552
67390698	67390721	14	-	26627737	HCT116	viability after 6 days	GCGTCGCTTTGTTCTAAGGAAGG	PLEK2	ENSG00000100558	0.3571258442051122	[477]	[190,43]	2	hSpCas9	negative selection	1776862
67392352	67392375	14	-	26627737	HCT116	viability after 6 days	TGTGGAGTTAAGTGGCACGGTGG	PLEK2	ENSG00000100558	1.0083717195857265	[979]	[394,262]	5	hSpCas9	negative selection	1776863
67392824	67392847	14	+	26627737	HCT116	viability after 6 days	GATGAGCCAGTCCACCAGGGAGG	PLEK2	ENSG00000100558	-2.0707169417253075	[249]	[9,8]	-8	hSpCas9	negative selection	1776864
67393206	67393229	14	-	26627737	HCT116	viability after 6 days	AAGATGCACGATAGCAACACCGG	PLEK2	ENSG00000100558	-0.22210082935062858	[618]	[192,22]	-1	hSpCas9	negative selection	1776865
67395466	67395489	14	-	26627737	HCT116	viability after 6 days	GGCTATTCATGCAGGGCAGCCGG	PLEK2	ENSG00000100558	0.5563549005553953	[393]	[248,3]	3	hSpCas9	negative selection	1776866
67397712	67397735	14	+	26627737	HCT116	viability after 6 days	GGAGGATCCGGCCCTTGGGAGGG	PLEK2	ENSG00000100558	0.1258552167461504	[498]	[238,0]	0	hSpCas9	negative selection	1776867
67390698	67390721	14	-	26627737	HCT116	viability after 8 days	GCGTCGCTTTGTTCTAAGGAAGG	PLEK2	ENSG00000100558	0.6333147152947998	[249]	[209,219,210]	6	hSpCas9	negative selection	1859177
67392352	67392375	14	-	26627737	HCT116	viability after 8 days	TGTGGAGTTAAGTGGCACGGTGG	PLEK2	ENSG00000100558	0.6364130426216775	[194]	[212,129,158]	6	hSpCas9	negative selection	1859178
67392824	67392847	14	+	26627737	HCT116	viability after 8 days	GATGAGCCAGTCCACCAGGGAGG	PLEK2	ENSG00000100558	-0.3972213683715835	[268]	[121,117,97]	-5	hSpCas9	negative selection	1859179
67393206	67393229	14	-	26627737	HCT116	viability after 8 days	AAGATGCACGATAGCAACACCGG	PLEK2	ENSG00000100558	-0.991572938090651	[602]	[105,207,185]	-8	hSpCas9	negative selection	1859180
67395466	67395489	14	-	26627737	HCT116	viability after 8 days	GGCTATTCATGCAGGGCAGCCGG	PLEK2	ENSG00000100558	0.5104396485027279	[128]	[98,125,78]	5	hSpCas9	negative selection	1859181
67397712	67397735	14	+	26627737	HCT116	viability after 8 days	GGAGGATCCGGCCCTTGGGAGGG	PLEK2	ENSG00000100558	-0.5289289624898441	[134]	[34,36,81]	-6	hSpCas9	negative selection	1859182
67390698	67390721	14	-	26627737	HCT116	viability after 9 days	GCGTCGCTTTGTTCTAAGGAAGG	PLEK2	ENSG00000100558	-0.35631628856141084	[477]	[92,104]	-3	hSpCas9	negative selection	1941492
67392352	67392375	14	-	26627737	HCT116	viability after 9 days	TGTGGAGTTAAGTGGCACGGTGG	PLEK2	ENSG00000100558	-0.2745960413723107	[979]	[403,67]	-2	hSpCas9	negative selection	1941493
67392824	67392847	14	+	26627737	HCT116	viability after 9 days	GATGAGCCAGTCCACCAGGGAGG	PLEK2	ENSG00000100558	0.2908809649727959	[249]	[122,48]	2	hSpCas9	negative selection	1941494
67393206	67393229	14	-	26627737	HCT116	viability after 9 days	AAGATGCACGATAGCAACACCGG	PLEK2	ENSG00000100558	-0.06026176830077809	[618]	[267,71]	0	hSpCas9	negative selection	1941495
67395466	67395489	14	-	26627737	HCT116	viability after 9 days	GGCTATTCATGCAGGGCAGCCGG	PLEK2	ENSG00000100558	1.0127577373712973	[393]	[180,236]	7	hSpCas9	negative selection	1941496
67397712	67397735	14	+	26627737	HCT116	viability after 9 days	GGAGGATCCGGCCCTTGGGAGGG	PLEK2	ENSG00000100558	-1.8092947767393504	[498]	[13,56]	-8	hSpCas9	negative selection	1941497
67390698	67390721	14	-	26627737	HCT116	viability after 12 days	GCGTCGCTTTGTTCTAAGGAAGG	PLEK2	ENSG00000100558	0.27950981886654647	[249]	[99,215,168]	3	hSpCas9	negative selection	2023807
67392352	67392375	14	-	26627737	HCT116	viability after 12 days	TGTGGAGTTAAGTGGCACGGTGG	PLEK2	ENSG00000100558	0.7926851712110738	[194]	[155,199,178]	7	hSpCas9	negative selection	2023808
67392824	67392847	14	+	26627737	HCT116	viability after 12 days	GATGAGCCAGTCCACCAGGGAGG	PLEK2	ENSG00000100558	-0.7969510569069584	[268]	[112,26,99]	-7	hSpCas9	negative selection	2023809
67393206	67393229	14	-	26627737	HCT116	viability after 12 days	AAGATGCACGATAGCAACACCGG	PLEK2	ENSG00000100558	-0.37277968220542246	[602]	[255,235,240]	-4	hSpCas9	negative selection	2023810
67395466	67395489	14	-	26627737	HCT116	viability after 12 days	GGCTATTCATGCAGGGCAGCCGG	PLEK2	ENSG00000100558	0.24266253750926003	[128]	[70,61,107]	2	hSpCas9	negative selection	2023811
67397712	67397735	14	+	26627737	HCT116	viability after 12 days	GGAGGATCCGGCCCTTGGGAGGG	PLEK2	ENSG00000100558	0.00782190375253733	[134]	[41,88,85]	0	hSpCas9	negative selection	2023812
67390698	67390721	14	-	26627737	HCT116	viability after 15 days	GCGTCGCTTTGTTCTAAGGAAGG	PLEK2	ENSG00000100558	0.5960208683942985	[249]	[177,225,241]	5	hSpCas9	negative selection	2106122
67392352	67392375	14	-	26627737	HCT116	viability after 15 days	TGTGGAGTTAAGTGGCACGGTGG	PLEK2	ENSG00000100558	0.19637034227826977	[194]	[176,95,117]	2	hSpCas9	negative selection	2106123
67392824	67392847	14	+	26627737	HCT116	viability after 15 days	GATGAGCCAGTCCACCAGGGAGG	PLEK2	ENSG00000100558	0.27615297903654	[268]	[278,154,138]	2	hSpCas9	negative selection	2106124
67393206	67393229	14	-	26627737	HCT116	viability after 15 days	AAGATGCACGATAGCAACACCGG	PLEK2	ENSG00000100558	-0.6663884322223206	[602]	[205,136,308]	-6	hSpCas9	negative selection	2106125
67395466	67395489	14	-	26627737	HCT116	viability after 15 days	GGCTATTCATGCAGGGCAGCCGG	PLEK2	ENSG00000100558	0.48344833887530314	[128]	[121,89,100]	4	hSpCas9	negative selection	2106126
67397712	67397735	14	+	26627737	HCT116	viability after 15 days	GGAGGATCCGGCCCTTGGGAGGG	PLEK2	ENSG00000100558	-0.002795296517033252	[134]	[76,69,84]	0	hSpCas9	negative selection	2106127
67390698	67390721	14	-	26627737	HCT116	viability after 18 days	GCGTCGCTTTGTTCTAAGGAAGG	PLEK2	ENSG00000100558	-0.04504408537821725	[249]	[67,123,160]	0	hSpCas9	negative selection	2188437
67392352	67392375	14	-	26627737	HCT116	viability after 18 days	TGTGGAGTTAAGTGGCACGGTGG	PLEK2	ENSG00000100558	1.1026825696945781	[194]	[288,92,233]	8	hSpCas9	negative selection	2188438
67392824	67392847	14	+	26627737	HCT116	viability after 18 days	GATGAGCCAGTCCACCAGGGAGG	PLEK2	ENSG00000100558	-0.012345943884415705	[268]	[271,42,74]	0	hSpCas9	negative selection	2188439
67393206	67393229	14	-	26627737	HCT116	viability after 18 days	AAGATGCACGATAGCAACACCGG	PLEK2	ENSG00000100558	0.27266074901969106	[602]	[411,134,531]	2	hSpCas9	negative selection	2188440
67395466	67395489	14	-	26627737	HCT116	viability after 18 days	GGCTATTCATGCAGGGCAGCCGG	PLEK2	ENSG00000100558	0.4479108839934687	[128]	[48,75,132]	4	hSpCas9	negative selection	2188441
67397712	67397735	14	+	26627737	HCT116	viability after 18 days	GGAGGATCCGGCCCTTGGGAGGG	PLEK2	ENSG00000100558	-0.4866634250165307	[134]	[22,53,62]	-4	hSpCas9	negative selection	2188442
67397661	67397684	14	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CCTGGAGTATGAAAACCGACCGG	PLEK2	ENSG00000100558	0.06036846991567152	[4,4]	[3,4]	1	hSpCas9	positive selection	3011866
67392808	67392831	14	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCTCATCTCCAACAGCTTCACGG	PLEK2	ENSG00000100558	0.15262588603276395	[5,5]	[5,4]	3	hSpCas9	positive selection	3011867
67395534	67395557	14	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GGCCTCCAGGAAGTACTCCGTGG	PLEK2	ENSG00000100558	0.5176305413992122	[2,2]	[3,4]	9	hSpCas9	positive selection	3011868
67397695	67397718	14	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TGATGGTGCAGCCATCCAGGAGG	PLEK2	ENSG00000100558	0.2774651607392137	[2,3]	[3,3]	6	hSpCas9	positive selection	3011869
67397661	67397684	14	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CCTGGAGTATGAAAACCGACCGG	PLEK2	ENSG00000100558	-0.4777276084598318	[4,4]	[3,1]	-6	hSpCas9	positive selection	3079724
67392808	67392831	14	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCTCATCTCCAACAGCTTCACGG	PLEK2	ENSG00000100558	0.33349863385916023	[5,5]	[5,4]	6	hSpCas9	positive selection	3079725
67395534	67395557	14	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GGCCTCCAGGAAGTACTCCGTGG	PLEK2	ENSG00000100558	-0.3561801396470883	[2,2]	[2,0]	-5	hSpCas9	positive selection	3079726
67397695	67397718	14	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TGATGGTGCAGCCATCCAGGAGG	PLEK2	ENSG00000100558	0.33341907795522396	[2,2]	[3,1]	6	hSpCas9	positive selection	3079727
67397766	67397789		+	24336571	A375	resistance to PLX after 7 days	ACACCAGCGTGTTCTGCCGAAGG	PLEK2	ENSG00000100558	-0.395300553666807	[9,9]	[7,5]	-9	hSpCas9	positive selection	3136135
67397782	67397805		-	24336571	A375	resistance to PLX after 7 days	AGGCGCGATGGTTCATCCTTCGG	PLEK2	ENSG00000100558	0.18733508374447747	[12,12]	[13,14]	6	hSpCas9	positive selection	3136136
67412008	67412031		+	24336571	A375	resistance to PLX after 7 days	GCGCACTCACCCTCTTGACCAGG	PLEK2	ENSG00000100558	0.3253641712893021	[13,13]	[12,21]	8	hSpCas9	positive selection	3136137
67412049	67412072		-	24336571	A375	resistance to PLX after 7 days	GCGGGCGGCGACATGGAGGACGG	PLEK2	ENSG00000100558	0.1294749717253505	[3,4]	[4,3]	4	hSpCas9	positive selection	3136138
67397766	67397789		+	24336571	A375	resistance to PLX after 14 days	ACACCAGCGTGTTCTGCCGAAGG	PLEK2	ENSG00000100558	0.029919914836927575	[7,8]	[3,3]	0	hSpCas9	positive selection	3193928
67397782	67397805		-	24336571	A375	resistance to PLX after 14 days	AGGCGCGATGGTTCATCCTTCGG	PLEK2	ENSG00000100558	-0.5202112704017089	[17,16]	[6,3]	-6	hSpCas9	positive selection	3193929
67412008	67412031		+	24336571	A375	resistance to PLX after 14 days	GCGCACTCACCCTCTTGACCAGG	PLEK2	ENSG00000100558	-0.0984161535089163	[13,19]	[7,6]	-1	hSpCas9	positive selection	3193930
67412049	67412072		-	24336571	A375	resistance to PLX after 14 days	GCGGGCGGCGACATGGAGGACGG	PLEK2	ENSG00000100558	0.3641386608295134	[3,2]	[1,1]	3	hSpCas9	positive selection	3193931
67397766	67397789		+	24336571	A375	viability after 7 days	ACACCAGCGTGTTCTGCCGAAGG	PLEK2	ENSG00000100558	0.05454378095450296	[9]	[9,9]	0	hSpCas9	negative selection	3251721
67397782	67397805		-	24336571	A375	viability after 7 days	AGGCGCGATGGTTCATCCTTCGG	PLEK2	ENSG00000100558	-0.2967454154744588	[16]	[12,12]	-4	hSpCas9	negative selection	3251722
67412008	67412031		+	24336571	A375	viability after 7 days	GCGCACTCACCCTCTTGACCAGG	PLEK2	ENSG00000100558	-0.7791844438303317	[25]	[13,13]	-8	hSpCas9	negative selection	3251723
67412049	67412072		-	24336571	A375	viability after 7 days	GCGGGCGGCGACATGGAGGACGG	PLEK2	ENSG00000100558	-0.11181307104094018	[4]	[3,4]	-2	hSpCas9	negative selection	3251724
67397766	67397789		+	24336571	A375	viability after 14 days	ACACCAGCGTGTTCTGCCGAAGG	PLEK2	ENSG00000100558	-0.1451970186602653	[9]	[7,8]	-2	hSpCas9	negative selection	3309514
67397782	67397805		-	24336571	A375	viability after 14 days	AGGCGCGATGGTTCATCCTTCGG	PLEK2	ENSG00000100558	0.13778072904365257	[16]	[17,16]	1	hSpCas9	negative selection	3309515
67412008	67412031		+	24336571	A375	viability after 14 days	GCGCACTCACCCTCTTGACCAGG	PLEK2	ENSG00000100558	-0.4926002354676596	[25]	[13,19]	-5	hSpCas9	negative selection	3309516
67412049	67412072		-	24336571	A375	viability after 14 days	GCGGGCGGCGACATGGAGGACGG	PLEK2	ENSG00000100558	-0.33534762366223037	[4]	[3,2]	-4	hSpCas9	negative selection	3309517
67395470	67395493	14	+	27383988	293T	resistance to West Nile virus (flavivirus)	CTGCCCTGCATGAATAGCCCCGG	PLEK2	ENSG00000100558	-0.9275491314624489	[290,290]	[0,0]	-6	hSpCas9	positive selection	3386258
67412038	67412061	14	-	27383988	293T	resistance to West Nile virus (flavivirus)	CATGGAGGACGGCGTGCTCAAGG	PLEK2	ENSG00000100558	1.1698633701954957	[67,67]	[0,0]	5	hSpCas9	positive selection	3386259
67412008	67412031	14	+	27383988	293T	resistance to West Nile virus (flavivirus)	GCGCACTCACCCTCTTGACCAGG	PLEK2	ENSG00000100558	-0.7870679079126183	[263,263]	[0,0]	-5	hSpCas9	positive selection	3386260
67397661	67397684	14	-	26780180	HT29	viability (Avana library 4 designs)	CCTGGAGTATGAAAACCGACCGG	PLEK2	ENSG00000100558	1.16446853538011	[]	[]	4	hSpCas9	negative selection	3449957
67392808	67392831	14	-	26780180	HT29	viability (Avana library 4 designs)	GCTCATCTCCAACAGCTTCACGG	PLEK2	ENSG00000100558	-0.353669436056073	[]	[]	-5	hSpCas9	negative selection	3449958
67395533	67395556	14	+	26780180	HT29	viability (Avana library 4 designs)	GGCCTCCAGGAAGTACTCCGTGG	PLEK2	ENSG00000100558	2.09666847964395	[]	[]	7	hSpCas9	negative selection	3449959
67397694	67397717	14	+	26780180	HT29	viability (Avana library 4 designs)	TGATGGTGCAGCCATCCAGGAGG	PLEK2	ENSG00000100558	0.135121465517106	[]	[]	0	hSpCas9	negative selection	3449960
67397661	67397684	14	-	26780180	A375	viability (Avana lentiCRISPRv2)	CCTGGAGTATGAAAACCGACCGG	PLEK2	ENSG00000100558	-2.67935217677999	[]	[]	-3	hSpCas9	negative selection	3544971
67395533	67395556	14	+	26780180	A375	viability (Avana lentiCRISPRv2)	GGCCTCCAGGAAGTACTCCGTGG	PLEK2	ENSG00000100558	5.35879647218714	[]	[]	8	hSpCas9	negative selection	3544972
67392808	67392831	14	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCTCATCTCCAACAGCTTCACGG	PLEK2	ENSG00000100558	0.758753263634436	[]	[]	1	hSpCas9	negative selection	3544973
67397694	67397717	14	+	26780180	A375	viability (Avana lentiCRISPRv2)	TGATGGTGCAGCCATCCAGGAGG	PLEK2	ENSG00000100558	5.23095575651635	[]	[]	8	hSpCas9	negative selection	3544974
67395464	67395487	14	-	26780180	A375	viability (Avana lentiCRISPRv2)	CTATTCATGCAGGGCAGCCGGGG	PLEK2	ENSG00000100558	0.810875302168637	[]	[]	1	hSpCas9	negative selection	3544975
67397723	67397746	14	-	26780180	A375	viability (Avana lentiCRISPRv2)	CGGAGAGTGACCCCTCCCAAGGG	PLEK2	ENSG00000100558	6.58247084735679	[]	[]	9	hSpCas9	negative selection	3544976
67397661	67397684	14	-	26780180	A375	viability (Avana lentiGuide)	CCTGGAGTATGAAAACCGACCGG	PLEK2	ENSG00000100558	-2.52808803418725	[]	[]	-4	hSpCas9	negative selection	3653630
67395533	67395556	14	+	26780180	A375	viability (Avana lentiGuide)	GGCCTCCAGGAAGTACTCCGTGG	PLEK2	ENSG00000100558	-2.27188105068879	[]	[]	-4	hSpCas9	negative selection	3653631
67392808	67392831	14	-	26780180	A375	viability (Avana lentiGuide)	GCTCATCTCCAACAGCTTCACGG	PLEK2	ENSG00000100558	-3.68633215043612	[]	[]	-6	hSpCas9	negative selection	3653632
67397694	67397717	14	+	26780180	A375	viability (Avana lentiGuide)	TGATGGTGCAGCCATCCAGGAGG	PLEK2	ENSG00000100558	9.03254868368734	[]	[]	6	hSpCas9	negative selection	3653633
67395464	67395487	14	-	26780180	A375	viability (Avana lentiGuide)	CTATTCATGCAGGGCAGCCGGGG	PLEK2	ENSG00000100558	0.110730277423054	[]	[]	0	hSpCas9	negative selection	3653634
67397723	67397746	14	-	26780180	A375	viability (Avana lentiGuide)	CGGAGAGTGACCCCTCCCAAGGG	PLEK2	ENSG00000100558	-1.36042233131102	[]	[]	-2	hSpCas9	negative selection	3653635
67397661	67397684	14	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CCTGGAGTATGAAAACCGACCGG	PLEK2	ENSG00000100558	-0.045132692159390225	[5]	[5,4]	-1	hSpCas9	positive selection	3762289
67395533	67395556	14	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGCCTCCAGGAAGTACTCCGTGG	PLEK2	ENSG00000100558	0.08575648084325754	[3]	[5,2]	2	hSpCas9	positive selection	3762290
67392808	67392831	14	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCTCATCTCCAACAGCTTCACGG	PLEK2	ENSG00000100558	-0.15201538260095748	[6]	[5,4]	-2	hSpCas9	positive selection	3762291
67397694	67397717	14	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TGATGGTGCAGCCATCCAGGAGG	PLEK2	ENSG00000100558	0.2526772422496687	[5]	[6,5]	7	hSpCas9	positive selection	3762292
67395464	67395487	14	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CTATTCATGCAGGGCAGCCGGGG	PLEK2	ENSG00000100558	0.23713420656164	[3]	[4,4]	6	hSpCas9	positive selection	3762293
67397723	67397746	14	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CGGAGAGTGACCCCTCCCAAGGG	PLEK2	ENSG00000100558	0.2747594700236349	[4]	[5,5]	7	hSpCas9	positive selection	3762294
67397661	67397684	14	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CCTGGAGTATGAAAACCGACCGG	PLEK2	ENSG00000100558	0.09398344685911642	[6]	[4,6]	2	hSpCas9	positive selection	3870896
67395533	67395556	14	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGCCTCCAGGAAGTACTCCGTGG	PLEK2	ENSG00000100558	-0.20086519421600812	[4]	[5,0]	-3	hSpCas9	positive selection	3870897
67392808	67392831	14	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCTCATCTCCAACAGCTTCACGG	PLEK2	ENSG00000100558	0.25320385561770126	[6]	[6,7]	6	hSpCas9	positive selection	3870898
67397694	67397717	14	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TGATGGTGCAGCCATCCAGGAGG	PLEK2	ENSG00000100558	0.2083295765211878	[5]	[4,5]	5	hSpCas9	positive selection	3870899
67395464	67395487	14	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CTATTCATGCAGGGCAGCCGGGG	PLEK2	ENSG00000100558	0.1684783764770126	[4]	[4,3]	4	hSpCas9	positive selection	3870900
67397723	67397746	14	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CGGAGAGTGACCCCTCCCAAGGG	PLEK2	ENSG00000100558	0.29682555701868907	[4]	[5,4]	8	hSpCas9	positive selection	3870901
67397766	67397789	14	+	26780180	A375	viability	ACACCAGCGTGTTCTGCCGAAGG	PLEK2	ENSG00000100558	0.739728173003746	[]	[]	2	hSpCas9	negative selection	3981728
67397782	67397805	14	-	26780180	A375	viability	AGGCGCGATGGTTCATCCTTCGG	PLEK2	ENSG00000100558	1.13229045393556	[]	[]	6	hSpCas9	negative selection	3981729
67395512	67395535	14	+	26780180	A375	viability	ATCCCGCTCCTCTCGAGAACAGG	PLEK2	ENSG00000100558	0.712968719691978	[]	[]	2	hSpCas9	negative selection	3981730
67412038	67412061	14	-	26780180	A375	viability	CATGGAGGACGGCGTGCTCAAGG	PLEK2	ENSG00000100558	0.882943579679672	[]	[]	3	hSpCas9	negative selection	3981731
67395470	67395493	14	+	26780180	A375	viability	CTGCCCTGCATGAATAGCCCCGG	PLEK2	ENSG00000100558	1.43816453463699	[]	[]	8	hSpCas9	negative selection	3981732
67412008	67412031	14	+	26780180	A375	viability	GCGCACTCACCCTCTTGACCAGG	PLEK2	ENSG00000100558	1.35621483555768	[]	[]	7	hSpCas9	negative selection	3981733
67397766	67397789	14	+	26780180	HT29	viability (GeCKOv2 library)	ACACCAGCGTGTTCTGCCGAAGG	PLEK2	ENSG00000100558	0.434437592235362	[]	[]	1	hSpCas9	negative selection	4089694
67397782	67397805	14	-	26780180	HT29	viability (GeCKOv2 library)	AGGCGCGATGGTTCATCCTTCGG	PLEK2	ENSG00000100558	1.24788002463672	[]	[]	6	hSpCas9	negative selection	4089695
67395512	67395535	14	+	26780180	HT29	viability (GeCKOv2 library)	ATCCCGCTCCTCTCGAGAACAGG	PLEK2	ENSG00000100558	0.987822083879985	[]	[]	4	hSpCas9	negative selection	4089696
67412038	67412061	14	-	26780180	HT29	viability (GeCKOv2 library)	CATGGAGGACGGCGTGCTCAAGG	PLEK2	ENSG00000100558	1.03675766739414	[]	[]	5	hSpCas9	negative selection	4089697
67395470	67395493	14	+	26780180	HT29	viability (GeCKOv2 library)	CTGCCCTGCATGAATAGCCCCGG	PLEK2	ENSG00000100558	2.89829150960884	[]	[]	9	hSpCas9	negative selection	4089698
67412008	67412031	14	+	26780180	HT29	viability (GeCKOv2 library)	GCGCACTCACCCTCTTGACCAGG	PLEK2	ENSG00000100558	1.70517534101593	[]	[]	8	hSpCas9	negative selection	4089699
67397766	67397789	14	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	ACACCAGCGTGTTCTGCCGAAGG	PLEK2	ENSG00000100558	-0.3280667001561925	[3]	[1,1]	-7	hSpCas9	positive selection	4161139
67397782	67397805	14	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	AGGCGCGATGGTTCATCCTTCGG	PLEK2	ENSG00000100558	0.008097002908329695	[3]	[1,2]	0	hSpCas9	positive selection	4161140
67412008	67412031	14	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GCGCACTCACCCTCTTGACCAGG	PLEK2	ENSG00000100558	-0.1043839917292293	[4]	[2,2]	-2	hSpCas9	positive selection	4161141
67412049	67412072	14	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GCGGGCGGCGACATGGAGGACGG	PLEK2	ENSG00000100558	-0.19146394599075067	[1]	[0,0]	-4	hSpCas9	positive selection	4161142
67397766	67397789	14	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	ACACCAGCGTGTTCTGCCGAAGG	PLEK2	ENSG00000100558	0.3094301593339475	[2]	[3,0,1,0]	2	hSpCas9	positive selection	4225161
67397782	67397805	14	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	AGGCGCGATGGTTCATCCTTCGG	PLEK2	ENSG00000100558	0.7091602751517069	[4]	[3,3,0,3]	4	hSpCas9	positive selection	4225162
67412008	67412031	14	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GCGCACTCACCCTCTTGACCAGG	PLEK2	ENSG00000100558	0.25561469488423455	[3]	[3,1,2,0]	2	hSpCas9	positive selection	4225163
67412049	67412072	14	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GCGGGCGGCGACATGGAGGACGG	PLEK2	ENSG00000100558	-0.18812945338846276	[1]	[0,0,0,0]	-3	hSpCas9	positive selection	4225164
67395512	67395535	14	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ATCCCGCTCCTCTCGAGAACAGG	PLEK2	ENSG00000100558	0.01794176041225836	[2]	[3,1]	0	hSpCas9	positive selection	4290708
67397782	67397805	14	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AGGCGCGATGGTTCATCCTTCGG	PLEK2	ENSG00000100558	0.21224338811117002	[3]	[3,2]	4	hSpCas9	positive selection	4290709
67397766	67397789	14	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ACACCAGCGTGTTCTGCCGAAGG	PLEK2	ENSG00000100558	0.2716793824264867	[4]	[4,3]	5	hSpCas9	positive selection	4290710
67395470	67395493	14	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CTGCCCTGCATGAATAGCCCCGG	PLEK2	ENSG00000100558	-0.6132895687170535	[3]	[2,0]	-8	hSpCas9	positive selection	4354960
67412038	67412061	14	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CATGGAGGACGGCGTGCTCAAGG	PLEK2	ENSG00000100558	0.33366906728373324	[1]	[1,1]	6	hSpCas9	positive selection	4354961
67412008	67412031	14	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GCGCACTCACCCTCTTGACCAGG	PLEK2	ENSG00000100558	-0.04683415041605808	[3]	[3,1]	-1	hSpCas9	positive selection	4354962
67392796	67392818	14	-	27760321	OCIAML3	viability	AGCTTCACGGCCAGCCGTCTGG	PLEK2	ENSG00000100558	0.4572396069573679	[1018,959]	[844,1347]	5	hSpCas9	negative selection	4428477
67395473	67395495	14	-	27760321	OCIAML3	viability	CACCGGGGCTATTCATGCAGGG	PLEK2	ENSG00000100558	0.35262976218737974	[605,389]	[470,514]	4	hSpCas9	negative selection	4428478
67395513	67395535	14	+	27760321	OCIAML3	viability	TCCCGCTCCTCTCGAGAACAGG	PLEK2	ENSG00000100558	0.1899712953079684	[624,500]	[445,568]	2	hSpCas9	negative selection	4428479
67397662	67397684	14	+	27760321	OCIAML3	viability	CGGTCGGTTTTCATACTCCAGG	PLEK2	ENSG00000100558	0.44688553389417957	[483,391]	[440,494]	5	hSpCas9	negative selection	4428480
67397748	67397770	14	-	27760321	OCIAML3	viability	GTGTACTACAAGCTTGAGGGGG	PLEK2	ENSG00000100558	-0.17724981028338255	[462,331]	[183,386]	-2	hSpCas9	negative selection	4428481
67392796	67392818	14	-	27760321	OCIAML2	viability	AGCTTCACGGCCAGCCGTCTGG	PLEK2	ENSG00000100558	0.17835762454909587	[1018,959]	[761,1096]	2	hSpCas9	negative selection	4511940
67395473	67395495	14	-	27760321	OCIAML2	viability	CACCGGGGCTATTCATGCAGGG	PLEK2	ENSG00000100558	0.46598794701718804	[605,389]	[471,648]	6	hSpCas9	negative selection	4511941
67395513	67395535	14	+	27760321	OCIAML2	viability	TCCCGCTCCTCTCGAGAACAGG	PLEK2	ENSG00000100558	-0.15360016705165544	[624,500]	[372,451]	-2	hSpCas9	negative selection	4511942
67397662	67397684	14	+	27760321	OCIAML2	viability	CGGTCGGTTTTCATACTCCAGG	PLEK2	ENSG00000100558	0.3832364144235532	[483,391]	[403,532]	5	hSpCas9	negative selection	4511943
67397748	67397770	14	-	27760321	OCIAML2	viability	GTGTACTACAAGCTTGAGGGGG	PLEK2	ENSG00000100558	-0.8178010927597086	[462,331]	[161,204]	-7	hSpCas9	negative selection	4511944
67392796	67392818	14	-	27760321	MV411	viability	AGCTTCACGGCCAGCCGTCTGG	PLEK2	ENSG00000100558	1.1408918135586086	[1018,959]	[1345,1583]	8	hSpCas9	negative selection	4595403
67395473	67395495	14	-	27760321	MV411	viability	CACCGGGGCTATTCATGCAGGG	PLEK2	ENSG00000100558	0.3408911730630477	[605,389]	[386,444]	2	hSpCas9	negative selection	4595404
67395513	67395535	14	+	27760321	MV411	viability	TCCCGCTCCTCTCGAGAACAGG	PLEK2	ENSG00000100558	-0.2997115644873234	[624,500]	[172,490]	-2	hSpCas9	negative selection	4595405
67397662	67397684	14	+	27760321	MV411	viability	CGGTCGGTTTTCATACTCCAGG	PLEK2	ENSG00000100558	1.2834742108182922	[483,391]	[977,281]	8	hSpCas9	negative selection	4595406
67397748	67397770	14	-	27760321	MV411	viability	GTGTACTACAAGCTTGAGGGGG	PLEK2	ENSG00000100558	0.2706101404382988	[462,331]	[299,332]	2	hSpCas9	negative selection	4595407
67392796	67392818	14	-	27760321	HL60	viability	AGCTTCACGGCCAGCCGTCTGG	PLEK2	ENSG00000100558	0.7486464969099844	[1018,959]	[1433,1279]	8	hSpCas9	negative selection	4678866
67395473	67395495	14	-	27760321	HL60	viability	CACCGGGGCTATTCATGCAGGG	PLEK2	ENSG00000100558	0.1675846507625109	[605,389]	[442,457]	2	hSpCas9	negative selection	4678867
67395513	67395535	14	+	27760321	HL60	viability	TCCCGCTCCTCTCGAGAACAGG	PLEK2	ENSG00000100558	-0.06532401711076175	[624,500]	[453,418]	0	hSpCas9	negative selection	4678868
67397662	67397684	14	+	27760321	HL60	viability	CGGTCGGTTTTCATACTCCAGG	PLEK2	ENSG00000100558	-0.6242935122412434	[483,391]	[176,287]	-6	hSpCas9	negative selection	4678869
67397748	67397770	14	-	27760321	HL60	viability	GTGTACTACAAGCTTGAGGGGG	PLEK2	ENSG00000100558	0.7176267882674808	[462,331]	[594,457]	7	hSpCas9	negative selection	4678870
67392796	67392818	14	-	27760321	HT1080	viability	AGCTTCACGGCCAGCCGTCTGG	PLEK2	ENSG00000100558	-0.14824257203297475	[959,748]	[299,314]	0	hSpCas9	negative selection	4762329
67395473	67395495	14	-	27760321	HT1080	viability	CACCGGGGCTATTCATGCAGGG	PLEK2	ENSG00000100558	0.4147473612836356	[389,304]	[206,159]	2	hSpCas9	negative selection	4762330
67395513	67395535	14	+	27760321	HT1080	viability	TCCCGCTCCTCTCGAGAACAGG	PLEK2	ENSG00000100558	-1.4886367819662507	[500,390]	[90,32]	-5	hSpCas9	negative selection	4762331
67397662	67397684	14	+	27760321	HT1080	viability	CGGTCGGTTTTCATACTCCAGG	PLEK2	ENSG00000100558	1.3323156577811917	[391,305]	[193,520]	7	hSpCas9	negative selection	4762332
67397748	67397770	14	-	27760321	HT1080	viability	GTGTACTACAAGCTTGAGGGGG	PLEK2	ENSG00000100558	-0.36711616878621206	[331,258]	[117,61]	-2	hSpCas9	negative selection	4762333
67392796	67392818	14	-	27760321	HT29	viability after 7 days	AGCTTCACGGCCAGCCGTCTGG	PLEK2	ENSG00000100558	-0.1270125863618332	[959,748]	[1388,731,951]	-2	hSpCas9	negative selection	4845792
67395473	67395495	14	-	27760321	HT29	viability after 7 days	CACCGGGGCTATTCATGCAGGG	PLEK2	ENSG00000100558	0.7012896373018171	[389,304]	[720,577,873]	9	hSpCas9	negative selection	4845793
67395513	67395535	14	+	27760321	HT29	viability after 7 days	TCCCGCTCCTCTCGAGAACAGG	PLEK2	ENSG00000100558	-0.2306429415518919	[500,390]	[588,601,294]	-3	hSpCas9	negative selection	4845794
67397662	67397684	14	+	27760321	HT29	viability after 7 days	CGGTCGGTTTTCATACTCCAGG	PLEK2	ENSG00000100558	-0.09379045984500481	[391,305]	[507,398,367]	-1	hSpCas9	negative selection	4845795
67397748	67397770	14	-	27760321	HT29	viability after 7 days	GTGTACTACAAGCTTGAGGGGG	PLEK2	ENSG00000100558	0.7273819240879311	[331,258]	[623,492,763]	9	hSpCas9	negative selection	4845796
67392796	67392818	14	-	27760321	HT29	viability after 25 days	AGCTTCACGGCCAGCCGTCTGG	PLEK2	ENSG00000100558	-0.14505154833645917	[959,748]	[806,848,1009]	-1	hSpCas9	negative selection	4929255
67395473	67395495	14	-	27760321	HT29	viability after 25 days	CACCGGGGCTATTCATGCAGGG	PLEK2	ENSG00000100558	0.15465671732135833	[389,304]	[430,361,543]	1	hSpCas9	negative selection	4929256
67395513	67395535	14	+	27760321	HT29	viability after 25 days	TCCCGCTCCTCTCGAGAACAGG	PLEK2	ENSG00000100558	-0.5168643936760591	[500,390]	[417,360,276]	-5	hSpCas9	negative selection	4929257
67397662	67397684	14	+	27760321	HT29	viability after 25 days	CGGTCGGTTTTCATACTCCAGG	PLEK2	ENSG00000100558	-0.34186619185898515	[391,305]	[436,105,401]	-3	hSpCas9	negative selection	4929258
67397748	67397770	14	-	27760321	HT29	viability after 25 days	GTGTACTACAAGCTTGAGGGGG	PLEK2	ENSG00000100558	-0.6422252231348979	[331,258]	[101,190,379]	-5	hSpCas9	negative selection	4929259
67392796	67392818	14	-	27760321	HT29	viability after 22 days	AGCTTCACGGCCAGCCGTCTGG	PLEK2	ENSG00000100558	-0.38009288609130054	[959,748]	[828,600,845]	-4	hSpCas9	negative selection	5012718
67395473	67395495	14	-	27760321	HT29	viability after 22 days	CACCGGGGCTATTCATGCAGGG	PLEK2	ENSG00000100558	0.5745219334108341	[389,304]	[576,464,754]	6	hSpCas9	negative selection	5012719
67395513	67395535	14	+	27760321	HT29	viability after 22 days	TCCCGCTCCTCTCGAGAACAGG	PLEK2	ENSG00000100558	-0.5030257539232734	[500,390]	[416,413,257]	-5	hSpCas9	negative selection	5012720
67397662	67397684	14	+	27760321	HT29	viability after 22 days	CGGTCGGTTTTCATACTCCAGG	PLEK2	ENSG00000100558	-0.2256330897411411	[391,305]	[461,222,346]	-2	hSpCas9	negative selection	5012721
67397748	67397770	14	-	27760321	HT29	viability after 22 days	GTGTACTACAAGCTTGAGGGGG	PLEK2	ENSG00000100558	-0.34941381643133	[331,258]	[339,133,328]	-3	hSpCas9	negative selection	5012722
67392796	67392818	14	-	27760321	HT29	viability after 19 days	AGCTTCACGGCCAGCCGTCTGG	PLEK2	ENSG00000100558	-0.007970747006226686	[959,748]	[1161,831,941]	0	hSpCas9	negative selection	5096181
67395473	67395495	14	-	27760321	HT29	viability after 19 days	CACCGGGGCTATTCATGCAGGG	PLEK2	ENSG00000100558	0.5511982751864017	[389,304]	[562,415,758]	5	hSpCas9	negative selection	5096182
67395513	67395535	14	+	27760321	HT29	viability after 19 days	TCCCGCTCCTCTCGAGAACAGG	PLEK2	ENSG00000100558	-0.1124477894727576	[500,390]	[686,420,334]	-1	hSpCas9	negative selection	5096183
67397662	67397684	14	+	27760321	HT29	viability after 19 days	CGGTCGGTTTTCATACTCCAGG	PLEK2	ENSG00000100558	-0.17856863035511775	[391,305]	[689,261,148]	-2	hSpCas9	negative selection	5096184
67397748	67397770	14	-	27760321	HT29	viability after 19 days	GTGTACTACAAGCTTGAGGGGG	PLEK2	ENSG00000100558	-0.014866591684264241	[331,258]	[255,457,282]	0	hSpCas9	negative selection	5096185
67392796	67392818	14	-	27760321	HT29	viability after 16 days	AGCTTCACGGCCAGCCGTCTGG	PLEK2	ENSG00000100558	0.06830270386358195	[959,748]	[1107,843,1068]	0	hSpCas9	negative selection	5179644
67395473	67395495	14	-	27760321	HT29	viability after 16 days	CACCGGGGCTATTCATGCAGGG	PLEK2	ENSG00000100558	0.49264274368413147	[389,304]	[1025,295,370]	5	hSpCas9	negative selection	5179645
67395513	67395535	14	+	27760321	HT29	viability after 16 days	TCCCGCTCCTCTCGAGAACAGG	PLEK2	ENSG00000100558	-0.5714718477487235	[500,390]	[504,154,367]	-5	hSpCas9	negative selection	5179646
67397662	67397684	14	+	27760321	HT29	viability after 16 days	CGGTCGGTTTTCATACTCCAGG	PLEK2	ENSG00000100558	-0.5393247561878844	[391,305]	[280,197,329]	-5	hSpCas9	negative selection	5179647
67397748	67397770	14	-	27760321	HT29	viability after 16 days	GTGTACTACAAGCTTGAGGGGG	PLEK2	ENSG00000100558	-0.6301819775046855	[331,258]	[158,159,317]	-5	hSpCas9	negative selection	5179648
67392796	67392818	14	-	27760321	HT29	viability after 13 days	AGCTTCACGGCCAGCCGTCTGG	PLEK2	ENSG00000100558	0.04722831272125583	[959,748]	[1113,994,966]	0	hSpCas9	negative selection	5263107
67395473	67395495	14	-	27760321	HT29	viability after 13 days	CACCGGGGCTATTCATGCAGGG	PLEK2	ENSG00000100558	0.7757271505262896	[389,304]	[685,562,813]	8	hSpCas9	negative selection	5263108
67395513	67395535	14	+	27760321	HT29	viability after 13 days	TCCCGCTCCTCTCGAGAACAGG	PLEK2	ENSG00000100558	0.13478639748257104	[500,390]	[923,461,331]	1	hSpCas9	negative selection	5263109
67397662	67397684	14	+	27760321	HT29	viability after 13 days	CGGTCGGTTTTCATACTCCAGG	PLEK2	ENSG00000100558	-0.24950134122340373	[391,305]	[333,215,463]	-3	hSpCas9	negative selection	5263110
67397748	67397770	14	-	27760321	HT29	viability after 13 days	GTGTACTACAAGCTTGAGGGGG	PLEK2	ENSG00000100558	-0.5078179470530741	[331,258]	[307,189,225]	-5	hSpCas9	negative selection	5263111
67392796	67392818	14	-	27760321	HT29	viability after 10 days	AGCTTCACGGCCAGCCGTCTGG	PLEK2	ENSG00000100558	0.015026578593200002	[959,748]	[1086,954,1185]	0	hSpCas9	negative selection	5346570
67395473	67395495	14	-	27760321	HT29	viability after 10 days	CACCGGGGCTATTCATGCAGGG	PLEK2	ENSG00000100558	0.44786931435455346	[389,304]	[735,475,560]	6	hSpCas9	negative selection	5346571
67395513	67395535	14	+	27760321	HT29	viability after 10 days	TCCCGCTCCTCTCGAGAACAGG	PLEK2	ENSG00000100558	-0.047643290954449635	[500,390]	[351,537,721]	0	hSpCas9	negative selection	5346572
67397662	67397684	14	+	27760321	HT29	viability after 10 days	CGGTCGGTTTTCATACTCCAGG	PLEK2	ENSG00000100558	-0.35739037493505926	[391,305]	[187,340,487]	-4	hSpCas9	negative selection	5346573
67397748	67397770	14	-	27760321	HT29	viability after 10 days	GTGTACTACAAGCTTGAGGGGG	PLEK2	ENSG00000100558	-0.033313428289058755	[331,258]	[271,249,551]	0	hSpCas9	negative selection	5346574
67392796	67392818	14	-	27760321	MOLM13	viability	AGCTTCACGGCCAGCCGTCTGG	PLEK2	ENSG00000100558	0.7281339796636579	[1018,959]	[1240,656]	5	hSpCas9	negative selection	5430033
67395473	67395495	14	-	27760321	MOLM13	viability	CACCGGGGCTATTCATGCAGGG	PLEK2	ENSG00000100558	1.0544667370865044	[605,389]	[620,535]	7	hSpCas9	negative selection	5430034
67395513	67395535	14	+	27760321	MOLM13	viability	TCCCGCTCCTCTCGAGAACAGG	PLEK2	ENSG00000100558	0.8601255365467138	[624,500]	[1100,123]	6	hSpCas9	negative selection	5430035
67397662	67397684	14	+	27760321	MOLM13	viability	CGGTCGGTTTTCATACTCCAGG	PLEK2	ENSG00000100558	0.7841203924997752	[483,391]	[506,351]	5	hSpCas9	negative selection	5430036
67397748	67397770	14	-	27760321	MOLM13	viability	GTGTACTACAAGCTTGAGGGGG	PLEK2	ENSG00000100558	0.843718458267002	[462,331]	[453,350]	6	hSpCas9	negative selection	5430037
67411879	67411902	14	+	27661255	K562	viability	GGCGGCCCGGTCCCACCATGGGG	PLEK2	ENSG00000100558	-0.04678234745563123	[724,636]	[583,479]	-2	dCas9-KRAB	negative selection	5502461
67411939	67411962	14	+	27661255	K562	viability	GCGCGTCTGGCCCCGCTCTAGGG	PLEK2	ENSG00000100558	0.3748592811602487	[70,122]	[139,64]	9	dCas9-KRAB	negative selection	5502462
67411768	67411791	14	-	27661255	K562	viability	GTTAGCGCAGTATGGAGTCGGGG	PLEK2	ENSG00000100558	0.05069325785273776	[848,1046]	[809,756]	1	dCas9-KRAB	negative selection	5502463
67412049	67412072	14	-	27661255	K562	viability	GCGGGCGGCGACATGGAGGACGG	PLEK2	ENSG00000100558	0.2763644831152261	[488,644]	[581,514]	8	dCas9-KRAB	negative selection	5502464
67412132	67412155	14	-	27661255	K562	viability	GCCGTGGGCGCGGACTGCGCGGG	PLEK2	ENSG00000100558	-0.04946298272717442	[360,353]	[261,287]	-2	dCas9-KRAB	negative selection	5502465
67412189	67412212	14	-	27661255	K562	viability	GCTCTGGACACGCGCCAGGGAGG	PLEK2	ENSG00000100558	-0.013626818949594277	[250,257]	[210,192]	0	dCas9-KRAB	negative selection	5502466
67395512	67395535	14	+	27260156	BXPC3	viability	ATCCCGCTCCTCTCGAGAACAGG	PLEK2	ENSG00000100558	-0.3413191930763493	[441]	[338,297,389,446]	-6	hSpCas9	negative selection	5563168
67397782	67397805	14	-	27260156	BXPC3	viability	AGGCGCGATGGTTCATCCTTCGG	PLEK2	ENSG00000100558	0.07422236388021958	[575]	[627,563,578,782]	1	hSpCas9	negative selection	5563169
67397766	67397789	14	+	27260156	BXPC3	viability	ACACCAGCGTGTTCTGCCGAAGG	PLEK2	ENSG00000100558	-0.04024713488594456	[1200]	[1119,1435,1118,1193]	-1	hSpCas9	negative selection	5563170
67395470	67395493	14	+	27260156	BXPC3	viability	CTGCCCTGCATGAATAGCCCCGG	PLEK2	ENSG00000100558	0.14329199661979708	[746]	[730,965,868,889]	3	hSpCas9	negative selection	5627420
67412038	67412061	14	-	27260156	BXPC3	viability	CATGGAGGACGGCGTGCTCAAGG	PLEK2	ENSG00000100558	0.20962385212409673	[161]	[132,269,171,210]	4	hSpCas9	negative selection	5627421
67412008	67412031	14	+	27260156	BXPC3	viability	GCGCACTCACCCTCTTGACCAGG	PLEK2	ENSG00000100558	0.3146694290350516	[638]	[646,920,890,880]	6	hSpCas9	negative selection	5627422
67395512	67395535	14	+	27260156	A673	viability	ATCCCGCTCCTCTCGAGAACAGG	PLEK2	ENSG00000100558	0.02122702762280461	[441]	[637,530,467,527]	0	hSpCas9	negative selection	5684419
67397782	67397805	14	-	27260156	A673	viability	AGGCGCGATGGTTCATCCTTCGG	PLEK2	ENSG00000100558	-0.3199027178949995	[575]	[642,418,618,546]	-7	hSpCas9	negative selection	5684420
67397766	67397789	14	+	27260156	A673	viability	ACACCAGCGTGTTCTGCCGAAGG	PLEK2	ENSG00000100558	-0.0048746070723220125	[1200]	[1589,1432,1390,1344]	0	hSpCas9	negative selection	5684421
67395470	67395493	14	+	27260156	A673	viability	CTGCCCTGCATGAATAGCCCCGG	PLEK2	ENSG00000100558	-0.1485023030809891	[746]	[843,779,777,839]	-4	hSpCas9	negative selection	5748671
67412038	67412061	14	-	27260156	A673	viability	CATGGAGGACGGCGTGCTCAAGG	PLEK2	ENSG00000100558	0.26244598472884073	[161]	[258,209,239,226]	6	hSpCas9	negative selection	5748672
67412008	67412031	14	+	27260156	A673	viability	GCGCACTCACCCTCTTGACCAGG	PLEK2	ENSG00000100558	0.10950750898893125	[638]	[859,820,797,834]	2	hSpCas9	negative selection	5748673
67395512	67395535	14	+	27260156	A375	viability	ATCCCGCTCCTCTCGAGAACAGG	PLEK2	ENSG00000100558	0.10568408217596263	[441]	[608,562,657,408]	1	hSpCas9	negative selection	5805670
67397782	67397805	14	-	27260156	A375	viability	AGGCGCGATGGTTCATCCTTCGG	PLEK2	ENSG00000100558	-0.2783059638012238	[575]	[602,584,410,614]	-4	hSpCas9	negative selection	5805671
67397766	67397789	14	+	27260156	A375	viability	ACACCAGCGTGTTCTGCCGAAGG	PLEK2	ENSG00000100558	0.13436549691951183	[1200]	[1615,1653,1662,1268]	2	hSpCas9	negative selection	5805672
67395470	67395493	14	+	27260156	A375	viability	CTGCCCTGCATGAATAGCCCCGG	PLEK2	ENSG00000100558	-0.0733134684760407	[746]	[954,1104,758,565]	-1	hSpCas9	negative selection	5869922
67412038	67412061	14	-	27260156	A375	viability	CATGGAGGACGGCGTGCTCAAGG	PLEK2	ENSG00000100558	0.3077774940208282	[161]	[258,214,211,245]	4	hSpCas9	negative selection	5869923
67412008	67412031	14	+	27260156	A375	viability	GCGCACTCACCCTCTTGACCAGG	PLEK2	ENSG00000100558	0.14592254082538436	[638]	[953,808,898,656]	2	hSpCas9	negative selection	5869924
67395512	67395535	14	+	27260156	COLO741	viability	ATCCCGCTCCTCTCGAGAACAGG	PLEK2	ENSG00000100558	0.015842538508212628	[441]	[659,626,441]	0	hSpCas9	negative selection	5926921
67397782	67397805	14	-	27260156	COLO741	viability	AGGCGCGATGGTTCATCCTTCGG	PLEK2	ENSG00000100558	0.00031124245168939746	[575]	[808,754,654]	0	hSpCas9	negative selection	5926922
67397766	67397789	14	+	27260156	COLO741	viability	ACACCAGCGTGTTCTGCCGAAGG	PLEK2	ENSG00000100558	0.04780492809341497	[1200]	[1704,1599,1468]	1	hSpCas9	negative selection	5926923
67395470	67395493	14	+	27260156	COLO741	viability	CTGCCCTGCATGAATAGCCCCGG	PLEK2	ENSG00000100558	-0.10288020754122318	[746]	[872,845,939]	-2	hSpCas9	negative selection	5991173
67412038	67412061	14	-	27260156	COLO741	viability	CATGGAGGACGGCGTGCTCAAGG	PLEK2	ENSG00000100558	0.3393719956842627	[161]	[263,269,251]	7	hSpCas9	negative selection	5991174
67412008	67412031	14	+	27260156	COLO741	viability	GCGCACTCACCCTCTTGACCAGG	PLEK2	ENSG00000100558	0.3080141258817105	[638]	[1188,847,1007]	6	hSpCas9	negative selection	5991175
67395512	67395535	14	+	27260156	CAL120	viability	ATCCCGCTCCTCTCGAGAACAGG	PLEK2	ENSG00000100558	-0.31968885232798694	[441]	[508,315,505]	-5	hSpCas9	negative selection	6048172
67397782	67397805	14	-	27260156	CAL120	viability	AGGCGCGATGGTTCATCCTTCGG	PLEK2	ENSG00000100558	-0.127067348991989	[575]	[532,582,830]	-2	hSpCas9	negative selection	6048173
67397766	67397789	14	+	27260156	CAL120	viability	ACACCAGCGTGTTCTGCCGAAGG	PLEK2	ENSG00000100558	-0.00923278378089809	[1200]	[1799,1344,1358]	0	hSpCas9	negative selection	6048174
67395470	67395493	14	+	27260156	CAL120	viability	CTGCCCTGCATGAATAGCCCCGG	PLEK2	ENSG00000100558	0.1192258367865352	[746]	[927,1289,801]	1	hSpCas9	negative selection	6112424
67412038	67412061	14	-	27260156	CAL120	viability	CATGGAGGACGGCGTGCTCAAGG	PLEK2	ENSG00000100558	-0.015404836957886303	[161]	[334,214,70]	0	hSpCas9	negative selection	6112425
67412008	67412031	14	+	27260156	CAL120	viability	GCGCACTCACCCTCTTGACCAGG	PLEK2	ENSG00000100558	-0.14754931414268868	[638]	[883,504,787]	-2	hSpCas9	negative selection	6112426
67395512	67395535	14	+	27260156	CADOES1	viability	ATCCCGCTCCTCTCGAGAACAGG	PLEK2	ENSG00000100558	-0.015924860716806752	[441]	[389,319,410,508]	0	hSpCas9	negative selection	6169423
67397782	67397805	14	-	27260156	CADOES1	viability	AGGCGCGATGGTTCATCCTTCGG	PLEK2	ENSG00000100558	-0.2354064658231929	[575]	[540,390,480,404]	-4	hSpCas9	negative selection	6169424
67397766	67397789	14	+	27260156	CADOES1	viability	ACACCAGCGTGTTCTGCCGAAGG	PLEK2	ENSG00000100558	-0.0680425486231051	[1200]	[1024,918,1122,1199]	-1	hSpCas9	negative selection	6169425
67395470	67395493	14	+	27260156	CADOES1	viability	CTGCCCTGCATGAATAGCCCCGG	PLEK2	ENSG00000100558	0.10825798320592905	[746]	[594,1049,643,705]	1	hSpCas9	negative selection	6233675
67412038	67412061	14	-	27260156	CADOES1	viability	CATGGAGGACGGCGTGCTCAAGG	PLEK2	ENSG00000100558	0.14528858828263114	[161]	[99,231,214,117]	2	hSpCas9	negative selection	6233676
67412008	67412031	14	+	27260156	CADOES1	viability	GCGCACTCACCCTCTTGACCAGG	PLEK2	ENSG00000100558	-0.4373355778063863	[638]	[477,422,426,426]	-6	hSpCas9	negative selection	6233677
67395512	67395535	14	+	27260156	EWS502	viability	ATCCCGCTCCTCTCGAGAACAGG	PLEK2	ENSG00000100558	-0.17279433954724543	[441]	[410,373,437,440]	-3	hSpCas9	negative selection	6290674
67397782	67397805	14	-	27260156	EWS502	viability	AGGCGCGATGGTTCATCCTTCGG	PLEK2	ENSG00000100558	-0.03127800482871629	[575]	[485,695,445,777]	0	hSpCas9	negative selection	6290675
67397766	67397789	14	+	27260156	EWS502	viability	ACACCAGCGTGTTCTGCCGAAGG	PLEK2	ENSG00000100558	-0.10213544961886178	[1200]	[1148,1020,1328,1254]	-2	hSpCas9	negative selection	6290676
67395470	67395493	14	+	27260156	EWS502	viability	CTGCCCTGCATGAATAGCCCCGG	PLEK2	ENSG00000100558	0.19396619715431773	[746]	[849,945,807,1024]	3	hSpCas9	negative selection	6354926
67412038	67412061	14	-	27260156	EWS502	viability	CATGGAGGACGGCGTGCTCAAGG	PLEK2	ENSG00000100558	0.3870637888926618	[161]	[156,161,371,217]	6	hSpCas9	negative selection	6354927
67412008	67412031	14	+	27260156	EWS502	viability	GCGCACTCACCCTCTTGACCAGG	PLEK2	ENSG00000100558	-0.0735392080439155	[638]	[531,540,747,777]	-1	hSpCas9	negative selection	6354928
67395512	67395535	14	+	27260156	EW8	viability	ATCCCGCTCCTCTCGAGAACAGG	PLEK2	ENSG00000100558	0.22531347649079464	[441]	[369,409,473,404]	4	hSpCas9	negative selection	6411925
67397782	67397805	14	-	27260156	EW8	viability	AGGCGCGATGGTTCATCCTTCGG	PLEK2	ENSG00000100558	-0.5393639084000726	[575]	[360,274,278,379]	-7	hSpCas9	negative selection	6411926
67397766	67397789	14	+	27260156	EW8	viability	ACACCAGCGTGTTCTGCCGAAGG	PLEK2	ENSG00000100558	-0.07871811458233813	[1200]	[1316,893,742,803]	-1	hSpCas9	negative selection	6411927
67395470	67395493	14	+	27260156	EW8	viability	CTGCCCTGCATGAATAGCCCCGG	PLEK2	ENSG00000100558	0.026367645589741695	[746]	[875,538,478,621]	0	hSpCas9	negative selection	6476177
67412038	67412061	14	-	27260156	EW8	viability	CATGGAGGACGGCGTGCTCAAGG	PLEK2	ENSG00000100558	0.3047490362478953	[161]	[146,74,178,241]	5	hSpCas9	negative selection	6476178
67412008	67412031	14	+	27260156	EW8	viability	GCGCACTCACCCTCTTGACCAGG	PLEK2	ENSG00000100558	-0.02616549429463494	[638]	[437,551,418,630]	0	hSpCas9	negative selection	6476179
67395512	67395535	14	+	27260156	CORL105	viability	ATCCCGCTCCTCTCGAGAACAGG	PLEK2	ENSG00000100558	-0.3054740047796313	[441]	[467,415,389,397]	-5	hSpCas9	negative selection	6533176
67397782	67397805	14	-	27260156	CORL105	viability	AGGCGCGATGGTTCATCCTTCGG	PLEK2	ENSG00000100558	-0.3614601726681312	[575]	[582,391,514,611]	-6	hSpCas9	negative selection	6533177
67397766	67397789	14	+	27260156	CORL105	viability	ACACCAGCGTGTTCTGCCGAAGG	PLEK2	ENSG00000100558	-0.2098253700675019	[1200]	[1189,1138,1318,1230]	-4	hSpCas9	negative selection	6533178
67395470	67395493	14	+	27260156	CORL105	viability	CTGCCCTGCATGAATAGCCCCGG	PLEK2	ENSG00000100558	0.2706245120293509	[746]	[913,1017,1407,930]	5	hSpCas9	negative selection	6597428
67412038	67412061	14	-	27260156	CORL105	viability	CATGGAGGACGGCGTGCTCAAGG	PLEK2	ENSG00000100558	0.42661456909345197	[161]	[244,316,259,196]	7	hSpCas9	negative selection	6597429
67412008	67412031	14	+	27260156	CORL105	viability	GCGCACTCACCCTCTTGACCAGG	PLEK2	ENSG00000100558	0.006879610147814352	[638]	[678,704,993,664]	0	hSpCas9	negative selection	6597430
67395512	67395535	14	+	27260156	HS294T	viability	ATCCCGCTCCTCTCGAGAACAGG	PLEK2	ENSG00000100558	-0.09224731706509472	[441]	[204,115,150,166]	-1	hSpCas9	negative selection	6654427
67397782	67397805	14	-	27260156	HS294T	viability	AGGCGCGATGGTTCATCCTTCGG	PLEK2	ENSG00000100558	0.07748133505108573	[575]	[335,191,191,205]	1	hSpCas9	negative selection	6654428
67397766	67397789	14	+	27260156	HS294T	viability	ACACCAGCGTGTTCTGCCGAAGG	PLEK2	ENSG00000100558	-0.040015757053925016	[1200]	[286,376,481,722]	0	hSpCas9	negative selection	6654429
67395470	67395493	14	+	27260156	HS294T	viability	CTGCCCTGCATGAATAGCCCCGG	PLEK2	ENSG00000100558	0.17212170075303457	[746]	[287,214,354,474]	2	hSpCas9	negative selection	6718679
67412038	67412061	14	-	27260156	HS294T	viability	CATGGAGGACGGCGTGCTCAAGG	PLEK2	ENSG00000100558	-0.5478975403007169	[161]	[43,51,30,43]	-7	hSpCas9	negative selection	6718680
67412008	67412031	14	+	27260156	HS294T	viability	GCGCACTCACCCTCTTGACCAGG	PLEK2	ENSG00000100558	0.051175060267498906	[638]	[173,258,261,351]	0	hSpCas9	negative selection	6718681
67395512	67395535	14	+	27260156	HCC44	viability	ATCCCGCTCCTCTCGAGAACAGG	PLEK2	ENSG00000100558	-0.20881206059156882	[441]	[530,470,444,289]	-3	hSpCas9	negative selection	6775678
67397782	67397805	14	-	27260156	HCC44	viability	AGGCGCGATGGTTCATCCTTCGG	PLEK2	ENSG00000100558	-0.11426272852880914	[575]	[705,521,638,563]	-2	hSpCas9	negative selection	6775679
67397766	67397789	14	+	27260156	HCC44	viability	ACACCAGCGTGTTCTGCCGAAGG	PLEK2	ENSG00000100558	-0.3408214798556066	[1200]	[973,1084,1321,936]	-5	hSpCas9	negative selection	6775680
67395470	67395493	14	+	27260156	HCC44	viability	CTGCCCTGCATGAATAGCCCCGG	PLEK2	ENSG00000100558	-0.20389727864762802	[746]	[778,771,825,570]	-3	hSpCas9	negative selection	6839930
67412038	67412061	14	-	27260156	HCC44	viability	CATGGAGGACGGCGTGCTCAAGG	PLEK2	ENSG00000100558	-0.03318180674763327	[161]	[167,152,167,224]	0	hSpCas9	negative selection	6839931
67412008	67412031	14	+	27260156	HCC44	viability	GCGCACTCACCCTCTTGACCAGG	PLEK2	ENSG00000100558	-0.5676447624129397	[638]	[572,277,697,471]	-7	hSpCas9	negative selection	6839932
67395512	67395535	14	+	27260156	G402	viability	ATCCCGCTCCTCTCGAGAACAGG	PLEK2	ENSG00000100558	-0.35676750721540995	[441]	[794,261,423,254]	-4	hSpCas9	negative selection	6896929
67397782	67397805	14	-	27260156	G402	viability	AGGCGCGATGGTTCATCCTTCGG	PLEK2	ENSG00000100558	-0.5602549382215154	[575]	[541,383,361,613]	-6	hSpCas9	negative selection	6896930
67397766	67397789	14	+	27260156	G402	viability	ACACCAGCGTGTTCTGCCGAAGG	PLEK2	ENSG00000100558	-0.6727100325941814	[1200]	[1064,664,1454,514]	-7	hSpCas9	negative selection	6896931
67395470	67395493	14	+	27260156	G402	viability	CTGCCCTGCATGAATAGCCCCGG	PLEK2	ENSG00000100558	-0.06676393470730624	[746]	[819,822,960,863]	-1	hSpCas9	negative selection	6961181
67412038	67412061	14	-	27260156	G402	viability	CATGGAGGACGGCGTGCTCAAGG	PLEK2	ENSG00000100558	-0.08921580669588569	[161]	[192,145,252,150]	-1	hSpCas9	negative selection	6961182
67412008	67412031	14	+	27260156	G402	viability	GCGCACTCACCCTCTTGACCAGG	PLEK2	ENSG00000100558	-0.1519951917048175	[638]	[611,785,501,886]	-2	hSpCas9	negative selection	6961183
67395512	67395535	14	+	27260156	L33	viability	ATCCCGCTCCTCTCGAGAACAGG	PLEK2	ENSG00000100558	0.09513950422259151	[441]	[505,178,263,523]	2	hSpCas9	negative selection	7018180
67397782	67397805	14	-	27260156	L33	viability	AGGCGCGATGGTTCATCCTTCGG	PLEK2	ENSG00000100558	-0.02746074792605957	[575]	[726,270,343,322]	0	hSpCas9	negative selection	7018181
67397766	67397789	14	+	27260156	L33	viability	ACACCAGCGTGTTCTGCCGAAGG	PLEK2	ENSG00000100558	0.26106627287816986	[1200]	[1373,604,951,1393]	5	hSpCas9	negative selection	7018182
67395470	67395493	14	+	27260156	L33	viability	CTGCCCTGCATGAATAGCCCCGG	PLEK2	ENSG00000100558	-0.25039064681139966	[746]	[532,250,403,724]	-5	hSpCas9	negative selection	7082432
67412038	67412061	14	-	27260156	L33	viability	CATGGAGGACGGCGTGCTCAAGG	PLEK2	ENSG00000100558	-0.10894225333582397	[161]	[160,47,110,145]	-2	hSpCas9	negative selection	7082433
67412008	67412031	14	+	27260156	L33	viability	GCGCACTCACCCTCTTGACCAGG	PLEK2	ENSG00000100558	0.2649470154273732	[638]	[836,295,385,893]	5	hSpCas9	negative selection	7082434
67395512	67395535	14	+	27260156	K562	viability	ATCCCGCTCCTCTCGAGAACAGG	PLEK2	ENSG00000100558	0.27410443539439466	[441]	[685,569,209,453]	3	hSpCas9	negative selection	7139431
67397782	67397805	14	-	27260156	K562	viability	AGGCGCGATGGTTCATCCTTCGG	PLEK2	ENSG00000100558	0.07610111422101823	[575]	[665,423,778,314]	0	hSpCas9	negative selection	7139432
67397766	67397789	14	+	27260156	K562	viability	ACACCAGCGTGTTCTGCCGAAGG	PLEK2	ENSG00000100558	0.020691743705090193	[1200]	[1291,1137,1164,780]	0	hSpCas9	negative selection	7139433
67395470	67395493	14	+	27260156	K562	viability	CTGCCCTGCATGAATAGCCCCGG	PLEK2	ENSG00000100558	-0.08231697368528634	[746]	[762,580,429,724]	-1	hSpCas9	negative selection	7203683
67412038	67412061	14	-	27260156	K562	viability	CATGGAGGACGGCGTGCTCAAGG	PLEK2	ENSG00000100558	-0.28313098379254975	[161]	[93,143,110,121]	-4	hSpCas9	negative selection	7203684
67412008	67412031	14	+	27260156	K562	viability	GCGCACTCACCCTCTTGACCAGG	PLEK2	ENSG00000100558	-0.4327016975288602	[638]	[336,717,395,255]	-5	hSpCas9	negative selection	7203685
67395512	67395535	14	+	27260156	HT29	viability	ATCCCGCTCCTCTCGAGAACAGG	PLEK2	ENSG00000100558	0.1284016629263963	[441]	[555,563,699,527]	2	hSpCas9	negative selection	7260682
67397782	67397805	14	-	27260156	HT29	viability	AGGCGCGATGGTTCATCCTTCGG	PLEK2	ENSG00000100558	-0.12008418765763013	[575]	[697,714,582,592]	-2	hSpCas9	negative selection	7260683
67397766	67397789	14	+	27260156	HT29	viability	ACACCAGCGTGTTCTGCCGAAGG	PLEK2	ENSG00000100558	-0.12408025572829917	[1200]	[1367,1462,1293,1247]	-3	hSpCas9	negative selection	7260684
67395470	67395493	14	+	27260156	HT29	viability	CTGCCCTGCATGAATAGCCCCGG	PLEK2	ENSG00000100558	0.07110646578729252	[746]	[1081,1086,939,746]	1	hSpCas9	negative selection	7324934
67412038	67412061	14	-	27260156	HT29	viability	CATGGAGGACGGCGTGCTCAAGG	PLEK2	ENSG00000100558	0.24597809285748684	[161]	[299,263,194,186]	5	hSpCas9	negative selection	7324935
67412008	67412031	14	+	27260156	HT29	viability	GCGCACTCACCCTCTTGACCAGG	PLEK2	ENSG00000100558	-0.07572949236569876	[638]	[820,682,661,773]	-1	hSpCas9	negative selection	7324936
67395512	67395535	14	+	27260156	MHHES1	viability	ATCCCGCTCCTCTCGAGAACAGG	PLEK2	ENSG00000100558	-0.01712990603118361	[441]	[465,506,339,611]	0	hSpCas9	negative selection	7381933
67397782	67397805	14	-	27260156	MHHES1	viability	AGGCGCGATGGTTCATCCTTCGG	PLEK2	ENSG00000100558	0.05029724089053922	[575]	[950,599,774,429]	0	hSpCas9	negative selection	7381934
67397766	67397789	14	+	27260156	MHHES1	viability	ACACCAGCGTGTTCTGCCGAAGG	PLEK2	ENSG00000100558	-0.012859333335647927	[1200]	[1231,1895,1385,952]	0	hSpCas9	negative selection	7381935
67395470	67395493	14	+	27260156	MHHES1	viability	CTGCCCTGCATGAATAGCCCCGG	PLEK2	ENSG00000100558	0.06971674981992837	[746]	[744,1020,993,774]	1	hSpCas9	negative selection	7446185
67412038	67412061	14	-	27260156	MHHES1	viability	CATGGAGGACGGCGTGCTCAAGG	PLEK2	ENSG00000100558	0.0033383527314188033	[161]	[58,398,195,99]	0	hSpCas9	negative selection	7446186
67412008	67412031	14	+	27260156	MHHES1	viability	GCGCACTCACCCTCTTGACCAGG	PLEK2	ENSG00000100558	0.08546080424118718	[638]	[1012,633,865,583]	1	hSpCas9	negative selection	7446187
67395512	67395535	14	+	27260156	MEWO	viability	ATCCCGCTCCTCTCGAGAACAGG	PLEK2	ENSG00000100558	0.026461320561326433	[441]	[647,291,367]	0	hSpCas9	negative selection	7503184
67397782	67397805	14	-	27260156	MEWO	viability	AGGCGCGATGGTTCATCCTTCGG	PLEK2	ENSG00000100558	0.0048174568287612796	[575]	[552,606,463]	0	hSpCas9	negative selection	7503185
67397766	67397789	14	+	27260156	MEWO	viability	ACACCAGCGTGTTCTGCCGAAGG	PLEK2	ENSG00000100558	0.2645377258737531	[1200]	[1455,1246,1366]	6	hSpCas9	negative selection	7503186
67395470	67395493	14	+	27260156	MEWO	viability	CTGCCCTGCATGAATAGCCCCGG	PLEK2	ENSG00000100558	-0.030704580638995504	[746]	[708,705,641]	0	hSpCas9	negative selection	7567436
67412038	67412061	14	-	27260156	MEWO	viability	CATGGAGGACGGCGTGCTCAAGG	PLEK2	ENSG00000100558	0.3084716230161346	[161]	[170,146,241]	6	hSpCas9	negative selection	7567437
67412008	67412031	14	+	27260156	MEWO	viability	GCGCACTCACCCTCTTGACCAGG	PLEK2	ENSG00000100558	-0.11150952752269072	[638]	[660,512,506]	-2	hSpCas9	negative selection	7567438
67395512	67395535	14	+	27260156	LNCAPCLONEFGC	viability	ATCCCGCTCCTCTCGAGAACAGG	PLEK2	ENSG00000100558	-0.109707310327652	[441]	[429,415,337,290]	-2	hSpCas9	negative selection	7624435
67397782	67397805	14	-	27260156	LNCAPCLONEFGC	viability	AGGCGCGATGGTTCATCCTTCGG	PLEK2	ENSG00000100558	-0.09436385616648063	[575]	[564,540,463,375]	-1	hSpCas9	negative selection	7624436
67397766	67397789	14	+	27260156	LNCAPCLONEFGC	viability	ACACCAGCGTGTTCTGCCGAAGG	PLEK2	ENSG00000100558	0.1420318532871485	[1200]	[1156,1232,1477,972]	2	hSpCas9	negative selection	7624437
67395470	67395493	14	+	27260156	LNCAPCLONEFGC	viability	CTGCCCTGCATGAATAGCCCCGG	PLEK2	ENSG00000100558	0.1555674871427306	[746]	[748,859,824,583]	2	hSpCas9	negative selection	7688687
67412038	67412061	14	-	27260156	LNCAPCLONEFGC	viability	CATGGAGGACGGCGTGCTCAAGG	PLEK2	ENSG00000100558	0.24875790978558543	[161]	[73,194,248,190]	4	hSpCas9	negative selection	7688688
67412008	67412031	14	+	27260156	LNCAPCLONEFGC	viability	GCGCACTCACCCTCTTGACCAGG	PLEK2	ENSG00000100558	-0.40709209474633956	[638]	[367,330,529,538]	-6	hSpCas9	negative selection	7688689
67395512	67395535	14	+	27260156	PANC0327	viability	ATCCCGCTCCTCTCGAGAACAGG	PLEK2	ENSG00000100558	0.0035367450305874293	[441]	[644,266,274,423]	0	hSpCas9	negative selection	7745686
67397782	67397805	14	-	27260156	PANC0327	viability	AGGCGCGATGGTTCATCCTTCGG	PLEK2	ENSG00000100558	-0.5809550170576017	[575]	[458,285,346,292]	-7	hSpCas9	negative selection	7745687
67397766	67397789	14	+	27260156	PANC0327	viability	ACACCAGCGTGTTCTGCCGAAGG	PLEK2	ENSG00000100558	-0.48124691379817996	[1200]	[992,601,975,525]	-6	hSpCas9	negative selection	7745688
67395470	67395493	14	+	27260156	PANC0327	viability	CTGCCCTGCATGAATAGCCCCGG	PLEK2	ENSG00000100558	-0.21531284764980396	[746]	[629,399,592,689]	-3	hSpCas9	negative selection	7809938
67412038	67412061	14	-	27260156	PANC0327	viability	CATGGAGGACGGCGTGCTCAAGG	PLEK2	ENSG00000100558	-1.2357306859113022	[161]	[38,96,71,29]	-9	hSpCas9	negative selection	7809939
67412008	67412031	14	+	27260156	PANC0327	viability	GCGCACTCACCCTCTTGACCAGG	PLEK2	ENSG00000100558	-0.08645099169015352	[638]	[445,562,394,722]	-1	hSpCas9	negative selection	7809940
67395512	67395535	14	+	27260156	NCIH2009	viability	ATCCCGCTCCTCTCGAGAACAGG	PLEK2	ENSG00000100558	-0.07951139241950093	[441]	[879,623,305]	-1	hSpCas9	negative selection	7866937
67397782	67397805	14	-	27260156	NCIH2009	viability	AGGCGCGATGGTTCATCCTTCGG	PLEK2	ENSG00000100558	-0.329510724277911	[575]	[444,782,650]	-4	hSpCas9	negative selection	7866938
67397766	67397789	14	+	27260156	NCIH2009	viability	ACACCAGCGTGTTCTGCCGAAGG	PLEK2	ENSG00000100558	-0.2524272527791602	[1200]	[1591,1395,1271]	-3	hSpCas9	negative selection	7866939
67395470	67395493	14	+	27260156	NCIH2009	viability	CTGCCCTGCATGAATAGCCCCGG	PLEK2	ENSG00000100558	0.2671644442235611	[746]	[1322,1041,1417]	3	hSpCas9	negative selection	7931189
67412038	67412061	14	-	27260156	NCIH2009	viability	CATGGAGGACGGCGTGCTCAAGG	PLEK2	ENSG00000100558	0.24892049294115526	[161]	[255,371,173]	3	hSpCas9	negative selection	7931190
67412008	67412031	14	+	27260156	NCIH2009	viability	GCGCACTCACCCTCTTGACCAGG	PLEK2	ENSG00000100558	0.2226019793280295	[638]	[1066,1119,939]	3	hSpCas9	negative selection	7931191
67395512	67395535	14	+	27260156	NCIH1373	viability	ATCCCGCTCCTCTCGAGAACAGG	PLEK2	ENSG00000100558	0.035094180763398194	[441]	[358,306,447,246]	0	hSpCas9	negative selection	7988188
67397782	67397805	14	-	27260156	NCIH1373	viability	AGGCGCGATGGTTCATCCTTCGG	PLEK2	ENSG00000100558	-0.5064360519330935	[575]	[321,622,624,48]	-5	hSpCas9	negative selection	7988189
67397766	67397789	14	+	27260156	NCIH1373	viability	ACACCAGCGTGTTCTGCCGAAGG	PLEK2	ENSG00000100558	-0.10247937040213562	[1200]	[1909,848,1114,337]	-1	hSpCas9	negative selection	7988190
67395470	67395493	14	+	27260156	NCIH1373	viability	CTGCCCTGCATGAATAGCCCCGG	PLEK2	ENSG00000100558	-0.17102958560784642	[746]	[692,769,841,169]	-2	hSpCas9	negative selection	8052440
67412038	67412061	14	-	27260156	NCIH1373	viability	CATGGAGGACGGCGTGCTCAAGG	PLEK2	ENSG00000100558	-0.4283653925056803	[161]	[162,36,218,34]	-4	hSpCas9	negative selection	8052441
67412008	67412031	14	+	27260156	NCIH1373	viability	GCGCACTCACCCTCTTGACCAGG	PLEK2	ENSG00000100558	0.10459137667005158	[638]	[718,700,719,248]	1	hSpCas9	negative selection	8052442
67395512	67395535	14	+	27260156	PATU8902	viability	ATCCCGCTCCTCTCGAGAACAGG	PLEK2	ENSG00000100558	-0.5714754605387294	[441]	[1064,194,260,128]	-5	hSpCas9	negative selection	8109439
67397782	67397805	14	-	27260156	PATU8902	viability	AGGCGCGATGGTTCATCCTTCGG	PLEK2	ENSG00000100558	-1.073009775633303	[575]	[281,323,381,555]	-7	hSpCas9	negative selection	8109440
67397766	67397789	14	+	27260156	PATU8902	viability	ACACCAGCGTGTTCTGCCGAAGG	PLEK2	ENSG00000100558	-1.2185536872814977	[1200]	[1134,648,446,700]	-8	hSpCas9	negative selection	8109441
67395470	67395493	14	+	27260156	PATU8902	viability	CTGCCCTGCATGAATAGCCCCGG	PLEK2	ENSG00000100558	-0.41357400775376985	[746]	[981,839,701,588]	-4	hSpCas9	negative selection	8173691
67412038	67412061	14	-	27260156	PATU8902	viability	CATGGAGGACGGCGTGCTCAAGG	PLEK2	ENSG00000100558	-1.1216885343809757	[161]	[73,119,38,210]	-7	hSpCas9	negative selection	8173692
67412008	67412031	14	+	27260156	PATU8902	viability	GCGCACTCACCCTCTTGACCAGG	PLEK2	ENSG00000100558	-0.2757307350048218	[638]	[857,376,1074,505]	-3	hSpCas9	negative selection	8173693
67395512	67395535	14	+	27260156	PANC1	viability	ATCCCGCTCCTCTCGAGAACAGG	PLEK2	ENSG00000100558	0.1199854139505982	[441]	[350,514,548,274]	2	hSpCas9	negative selection	8230690
67397782	67397805	14	-	27260156	PANC1	viability	AGGCGCGATGGTTCATCCTTCGG	PLEK2	ENSG00000100558	-0.38192093269063776	[575]	[405,426,368,327]	-5	hSpCas9	negative selection	8230691
67397766	67397789	14	+	27260156	PANC1	viability	ACACCAGCGTGTTCTGCCGAAGG	PLEK2	ENSG00000100558	-0.17290663108473114	[1200]	[938,1234,859,709]	-3	hSpCas9	negative selection	8230692
67395470	67395493	14	+	27260156	PANC1	viability	CTGCCCTGCATGAATAGCCCCGG	PLEK2	ENSG00000100558	-0.2550509416003281	[746]	[495,790,572,363]	-4	hSpCas9	negative selection	8294942
67412038	67412061	14	-	27260156	PANC1	viability	CATGGAGGACGGCGTGCTCAAGG	PLEK2	ENSG00000100558	0.5469247731162961	[161]	[203,339,202,106]	8	hSpCas9	negative selection	8294943
67412008	67412031	14	+	27260156	PANC1	viability	GCGCACTCACCCTCTTGACCAGG	PLEK2	ENSG00000100558	-0.31375483344160604	[638]	[507,469,313,465]	-5	hSpCas9	negative selection	8294944
67395512	67395535	14	+	27260156	PANC0813	viability	ATCCCGCTCCTCTCGAGAACAGG	PLEK2	ENSG00000100558	-0.9636114886863765	[441]	[333,329,189,218]	-8	hSpCas9	negative selection	8351941
67397782	67397805	14	-	27260156	PANC0813	viability	AGGCGCGATGGTTCATCCTTCGG	PLEK2	ENSG00000100558	-0.6354101720899349	[575]	[429,216,466,616]	-7	hSpCas9	negative selection	8351942
67397766	67397789	14	+	27260156	PANC0813	viability	ACACCAGCGTGTTCTGCCGAAGG	PLEK2	ENSG00000100558	-0.42767698763785333	[1200]	[1167,955,1227,863]	-6	hSpCas9	negative selection	8351943
67395470	67395493	14	+	27260156	PANC0813	viability	CTGCCCTGCATGAATAGCCCCGG	PLEK2	ENSG00000100558	-0.056988308263600684	[746]	[963,649,1129,651]	-1	hSpCas9	negative selection	8416193
67412038	67412061	14	-	27260156	PANC0813	viability	CATGGAGGACGGCGTGCTCAAGG	PLEK2	ENSG00000100558	-0.11528078067763414	[161]	[139,152,240,165]	-2	hSpCas9	negative selection	8416194
67412008	67412031	14	+	27260156	PANC0813	viability	GCGCACTCACCCTCTTGACCAGG	PLEK2	ENSG00000100558	-0.4579066098012894	[638]	[383,502,687,592]	-6	hSpCas9	negative selection	8416195
67395512	67395535	14	+	27260156	RDES	viability	ATCCCGCTCCTCTCGAGAACAGG	PLEK2	ENSG00000100558	-0.1844830894211722	[441]	[372,430,461,541]	-3	hSpCas9	negative selection	8473192
67397782	67397805	14	-	27260156	RDES	viability	AGGCGCGATGGTTCATCCTTCGG	PLEK2	ENSG00000100558	-0.016899794542016566	[575]	[740,534,610,706]	0	hSpCas9	negative selection	8473193
67397766	67397789	14	+	27260156	RDES	viability	ACACCAGCGTGTTCTGCCGAAGG	PLEK2	ENSG00000100558	-0.11017380833747437	[1200]	[1087,1211,1482,1363]	-2	hSpCas9	negative selection	8473194
67395470	67395493	14	+	27260156	RDES	viability	CTGCCCTGCATGAATAGCCCCGG	PLEK2	ENSG00000100558	0.0759957796042493	[746]	[850,767,953,1071]	1	hSpCas9	negative selection	8537444
67412038	67412061	14	-	27260156	RDES	viability	CATGGAGGACGGCGTGCTCAAGG	PLEK2	ENSG00000100558	-0.13879693256980996	[161]	[179,162,159,164]	-2	hSpCas9	negative selection	8537445
67412008	67412031	14	+	27260156	RDES	viability	GCGCACTCACCCTCTTGACCAGG	PLEK2	ENSG00000100558	0.1948997271146472	[638]	[784,793,841,948]	3	hSpCas9	negative selection	8537446
67395512	67395535	14	+	27260156	PC3	viability	ATCCCGCTCCTCTCGAGAACAGG	PLEK2	ENSG00000100558	0.14710781153474312	[441]	[310,473,1004,388]	3	hSpCas9	negative selection	8594443
67397782	67397805	14	-	27260156	PC3	viability	AGGCGCGATGGTTCATCCTTCGG	PLEK2	ENSG00000100558	-0.05730518085396963	[575]	[345,662,834,499]	-1	hSpCas9	negative selection	8594444
67397766	67397789	14	+	27260156	PC3	viability	ACACCAGCGTGTTCTGCCGAAGG	PLEK2	ENSG00000100558	-0.005854940741423453	[1200]	[949,859,2470,959]	0	hSpCas9	negative selection	8594445
67395470	67395493	14	+	27260156	PC3	viability	CTGCCCTGCATGAATAGCCCCGG	PLEK2	ENSG00000100558	-0.5456306827180163	[746]	[316,548,710,576]	-8	hSpCas9	negative selection	8658695
67412038	67412061	14	-	27260156	PC3	viability	CATGGAGGACGGCGTGCTCAAGG	PLEK2	ENSG00000100558	0.18570249591771337	[161]	[58,229,319,221]	4	hSpCas9	negative selection	8658696
67412008	67412031	14	+	27260156	PC3	viability	GCGCACTCACCCTCTTGACCAGG	PLEK2	ENSG00000100558	-0.15894234029917292	[638]	[393,416,770,814]	-4	hSpCas9	negative selection	8658697
67395512	67395535	14	+	27260156	PATU8988T	viability	ATCCCGCTCCTCTCGAGAACAGG	PLEK2	ENSG00000100558	0.25448692122049604	[441]	[448,728,512,354]	4	hSpCas9	negative selection	8715694
67397782	67397805	14	-	27260156	PATU8988T	viability	AGGCGCGATGGTTCATCCTTCGG	PLEK2	ENSG00000100558	-0.003541815020767114	[575]	[714,621,406,478]	0	hSpCas9	negative selection	8715695
67397766	67397789	14	+	27260156	PATU8988T	viability	ACACCAGCGTGTTCTGCCGAAGG	PLEK2	ENSG00000100558	0.13942902486343178	[1200]	[1055,1095,1635,1304]	2	hSpCas9	negative selection	8715696
67395470	67395493	14	+	27260156	PATU8988T	viability	CTGCCCTGCATGAATAGCCCCGG	PLEK2	ENSG00000100558	0.2889810725897598	[746]	[856,883,907,877]	5	hSpCas9	negative selection	8779946
67412038	67412061	14	-	27260156	PATU8988T	viability	CATGGAGGACGGCGTGCTCAAGG	PLEK2	ENSG00000100558	0.14799409540757336	[161]	[100,157,132,311]	2	hSpCas9	negative selection	8779947
67412008	67412031	14	+	27260156	PATU8988T	viability	GCGCACTCACCCTCTTGACCAGG	PLEK2	ENSG00000100558	0.3469434128116464	[638]	[854,894,625,776]	6	hSpCas9	negative selection	8779948
67395512	67395535	14	+	27260156	T47D	viability	ATCCCGCTCCTCTCGAGAACAGG	PLEK2	ENSG00000100558	-0.11140921851665901	[441]	[498,460,511,433]	-2	hSpCas9	negative selection	8836945
67397782	67397805	14	-	27260156	T47D	viability	AGGCGCGATGGTTCATCCTTCGG	PLEK2	ENSG00000100558	-0.35715895707433876	[575]	[477,552,544,515]	-6	hSpCas9	negative selection	8836946
67397766	67397789	14	+	27260156	T47D	viability	ACACCAGCGTGTTCTGCCGAAGG	PLEK2	ENSG00000100558	-0.1473571718614055	[1200]	[1235,1029,1429,1377]	-3	hSpCas9	negative selection	8836947
67395470	67395493	14	+	27260156	T47D	viability	CTGCCCTGCATGAATAGCCCCGG	PLEK2	ENSG00000100558	-0.08066802526671824	[746]	[878,790,816,806]	-2	hSpCas9	negative selection	8901197
67412038	67412061	14	-	27260156	T47D	viability	CATGGAGGACGGCGTGCTCAAGG	PLEK2	ENSG00000100558	-0.2223020652936567	[161]	[193,164,135,151]	-5	hSpCas9	negative selection	8901198
67412008	67412031	14	+	27260156	T47D	viability	GCGCACTCACCCTCTTGACCAGG	PLEK2	ENSG00000100558	-0.18268807798069536	[638]	[564,706,647,699]	-4	hSpCas9	negative selection	8901199
67395512	67395535	14	+	27260156	SU8686	viability	ATCCCGCTCCTCTCGAGAACAGG	PLEK2	ENSG00000100558	-0.05649158724239099	[441]	[464,495,378,307]	-1	hSpCas9	negative selection	8958196
67397782	67397805	14	-	27260156	SU8686	viability	AGGCGCGATGGTTCATCCTTCGG	PLEK2	ENSG00000100558	-0.46527618148153715	[575]	[378,362,475,451]	-6	hSpCas9	negative selection	8958197
67397766	67397789	14	+	27260156	SU8686	viability	ACACCAGCGTGTTCTGCCGAAGG	PLEK2	ENSG00000100558	-0.10997157233345356	[1200]	[994,1002,1241,1211]	-2	hSpCas9	negative selection	8958198
67395470	67395493	14	+	27260156	SU8686	viability	CTGCCCTGCATGAATAGCCCCGG	PLEK2	ENSG00000100558	0.16642204982768616	[746]	[663,834,980,866]	3	hSpCas9	negative selection	9022448
67412038	67412061	14	-	27260156	SU8686	viability	CATGGAGGACGGCGTGCTCAAGG	PLEK2	ENSG00000100558	-0.03957112388552342	[161]	[185,187,141,88]	0	hSpCas9	negative selection	9022449
67412008	67412031	14	+	27260156	SU8686	viability	GCGCACTCACCCTCTTGACCAGG	PLEK2	ENSG00000100558	0.11764756892002282	[638]	[646,739,625,734]	2	hSpCas9	negative selection	9022450
67395512	67395535	14	+	27260156	SKES1	viability	ATCCCGCTCCTCTCGAGAACAGG	PLEK2	ENSG00000100558	0.12180631312918827	[441]	[599,436,436,454]	2	hSpCas9	negative selection	9079447
67397782	67397805	14	-	27260156	SKES1	viability	AGGCGCGATGGTTCATCCTTCGG	PLEK2	ENSG00000100558	0.104453698599901	[575]	[534,678,762,495]	2	hSpCas9	negative selection	9079448
67397766	67397789	14	+	27260156	SKES1	viability	ACACCAGCGTGTTCTGCCGAAGG	PLEK2	ENSG00000100558	0.10207911921793733	[1200]	[1534,1267,1283,1097]	2	hSpCas9	negative selection	9079449
67395470	67395493	14	+	27260156	SKES1	viability	CTGCCCTGCATGAATAGCCCCGG	PLEK2	ENSG00000100558	-0.018651187996710172	[746]	[836,845,707,588]	0	hSpCas9	negative selection	9143699
67412038	67412061	14	-	27260156	SKES1	viability	CATGGAGGACGGCGTGCTCAAGG	PLEK2	ENSG00000100558	0.12429046172999891	[161]	[185,226,153,146]	2	hSpCas9	negative selection	9143700
67412008	67412031	14	+	27260156	SKES1	viability	GCGCACTCACCCTCTTGACCAGG	PLEK2	ENSG00000100558	-0.016727453978887974	[638]	[790,594,670,490]	0	hSpCas9	negative selection	9143701
67395512	67395535	14	+	27260156	TOV112D	viability	ATCCCGCTCCTCTCGAGAACAGG	PLEK2	ENSG00000100558	-0.03602150912901257	[441]	[498,421,571,241]	0	hSpCas9	negative selection	9200698
67397782	67397805	14	-	27260156	TOV112D	viability	AGGCGCGATGGTTCATCCTTCGG	PLEK2	ENSG00000100558	0.09015222447511306	[575]	[470,658,479,837]	1	hSpCas9	negative selection	9200699
67397766	67397789	14	+	27260156	TOV112D	viability	ACACCAGCGTGTTCTGCCGAAGG	PLEK2	ENSG00000100558	0.013759819272254337	[1200]	[1433,1229,1293,927]	0	hSpCas9	negative selection	9200700
67395470	67395493	14	+	27260156	TOV112D	viability	CTGCCCTGCATGAATAGCCCCGG	PLEK2	ENSG00000100558	-0.2810387242272492	[746]	[666,872,462,528]	-5	hSpCas9	negative selection	9264950
67412038	67412061	14	-	27260156	TOV112D	viability	CATGGAGGACGGCGTGCTCAAGG	PLEK2	ENSG00000100558	0.017168364116099566	[161]	[177,252,137,111]	0	hSpCas9	negative selection	9264951
67412008	67412031	14	+	27260156	TOV112D	viability	GCGCACTCACCCTCTTGACCAGG	PLEK2	ENSG00000100558	0.11022165918515436	[638]	[706,1037,453,650]	2	hSpCas9	negative selection	9264952
67395512	67395535	14	+	27260156	TC71	viability	ATCCCGCTCCTCTCGAGAACAGG	PLEK2	ENSG00000100558	0.16621427054627164	[441]	[470,599,476,584]	4	hSpCas9	negative selection	9321949
67397782	67397805	14	-	27260156	TC71	viability	AGGCGCGATGGTTCATCCTTCGG	PLEK2	ENSG00000100558	0.0015172047492180707	[575]	[589,554,696,628]	0	hSpCas9	negative selection	9321950
67397766	67397789	14	+	27260156	TC71	viability	ACACCAGCGTGTTCTGCCGAAGG	PLEK2	ENSG00000100558	0.1440105499738613	[1200]	[1213,1501,1456,1526]	3	hSpCas9	negative selection	9321951
67395470	67395493	14	+	27260156	TC71	viability	CTGCCCTGCATGAATAGCCCCGG	PLEK2	ENSG00000100558	-0.11171310363373421	[746]	[748,778,641,800]	-3	hSpCas9	negative selection	9386201
67412038	67412061	14	-	27260156	TC71	viability	CATGGAGGACGGCGTGCTCAAGG	PLEK2	ENSG00000100558	0.1269303387061118	[161]	[177,182,218,176]	3	hSpCas9	negative selection	9386202
67412008	67412031	14	+	27260156	TC71	viability	GCGCACTCACCCTCTTGACCAGG	PLEK2	ENSG00000100558	-0.02695991423004529	[638]	[652,576,662,804]	0	hSpCas9	negative selection	9386203
67395512	67395535	14	+	27260156	TC32	viability	ATCCCGCTCCTCTCGAGAACAGG	PLEK2	ENSG00000100558	0.21967785980526344	[441]	[597,297,587,495]	4	hSpCas9	negative selection	9443200
67397782	67397805	14	-	27260156	TC32	viability	AGGCGCGATGGTTCATCCTTCGG	PLEK2	ENSG00000100558	-0.1586937428125511	[575]	[408,490,540,483]	-3	hSpCas9	negative selection	9443201
67397766	67397789	14	+	27260156	TC32	viability	ACACCAGCGTGTTCTGCCGAAGG	PLEK2	ENSG00000100558	-0.15535115708182823	[1200]	[1003,684,1183,1291]	-3	hSpCas9	negative selection	9443202
67395470	67395493	14	+	27260156	TC32	viability	CTGCCCTGCATGAATAGCCCCGG	PLEK2	ENSG00000100558	0.055423217672459946	[746]	[604,527,846,1024]	1	hSpCas9	negative selection	9507452
67412038	67412061	14	-	27260156	TC32	viability	CATGGAGGACGGCGTGCTCAAGG	PLEK2	ENSG00000100558	0.15587516238273502	[161]	[160,179,128,187]	3	hSpCas9	negative selection	9507453
67412008	67412031	14	+	27260156	TC32	viability	GCGCACTCACCCTCTTGACCAGG	PLEK2	ENSG00000100558	0.04865210753404231	[638]	[494,566,813,640]	0	hSpCas9	negative selection	9507454
67390698	67390721	14	-	27869803	HPAFII	viability after 27 days	GCGTCGCTTTGTTCTAAGGAAGG	PLEK2	ENSG00000100558	-0.046424337091352075	[359]	[191,175,NaN]	0	hSpCas9	negative selection	9552088
67392352	67392375	14	-	27869803	HPAFII	viability after 27 days	TGTGGAGTTAAGTGGCACGGTGG	PLEK2	ENSG00000100558	0.19948819342606378	[166]	[210,8,NaN]	1	hSpCas9	negative selection	9552089
67392824	67392847	14	+	27869803	HPAFII	viability after 27 days	GATGAGCCAGTCCACCAGGGAGG	PLEK2	ENSG00000100558	0.3988861733012925	[87]	[66,55,NaN]	3	hSpCas9	negative selection	9552090
67393206	67393229	14	-	27869803	HPAFII	viability after 27 days	AAGATGCACGATAGCAACACCGG	PLEK2	ENSG00000100558	-0.6972380351595657	[366]	[58,168,NaN]	-5	hSpCas9	negative selection	9552091
67395466	67395489	14	-	27869803	HPAFII	viability after 27 days	GGCTATTCATGCAGGGCAGCCGG	PLEK2	ENSG00000100558	0.35246573961089456	[145]	[109,87,NaN]	3	hSpCas9	negative selection	9552092
67397712	67397735	14	+	27869803	HPAFII	viability after 27 days	GGAGGATCCGGCCCTTGGGAGGG	PLEK2	ENSG00000100558	-0.3455401885803986	[106]	[16,66,NaN]	-3	hSpCas9	negative selection	9552093
67390698	67390721	14	-	27869803	HPAFII	viability after 15 days	GCGTCGCTTTGTTCTAAGGAAGG	PLEK2	ENSG00000100558	0.14371471349041742	[359]	[559,344,NaN]	1	hSpCas9	negative selection	9634537
67392352	67392375	14	-	27869803	HPAFII	viability after 15 days	TGTGGAGTTAAGTGGCACGGTGG	PLEK2	ENSG00000100558	0.40009639926680085	[166]	[316,186,NaN]	4	hSpCas9	negative selection	9634538
67392824	67392847	14	+	27869803	HPAFII	viability after 15 days	GATGAGCCAGTCCACCAGGGAGG	PLEK2	ENSG00000100558	-0.14805977649266322	[87]	[101,74,NaN]	-2	hSpCas9	negative selection	9634539
67393206	67393229	14	-	27869803	HPAFII	viability after 15 days	AAGATGCACGATAGCAACACCGG	PLEK2	ENSG00000100558	-0.7379464967852281	[366]	[180,270,NaN]	-7	hSpCas9	negative selection	9634540
67395466	67395489	14	-	27869803	HPAFII	viability after 15 days	GGCTATTCATGCAGGGCAGCCGG	PLEK2	ENSG00000100558	0.001325110631112958	[145]	[206,125,NaN]	0	hSpCas9	negative selection	9634541
67397712	67397735	14	+	27869803	HPAFII	viability after 15 days	GGAGGATCCGGCCCTTGGGAGGG	PLEK2	ENSG00000100558	-1.1972583918249582	[106]	[51,48,NaN]	-8	hSpCas9	negative selection	9634542
67390698	67390721	14	-	27869803	ASPC1	viability after 36 days	GCGTCGCTTTGTTCTAAGGAAGG	PLEK2	ENSG00000100558	0.4107070494241417	[915]	[405,293,537]	4	hSpCas9	negative selection	9716986
67392352	67392375	14	-	27869803	ASPC1	viability after 36 days	TGTGGAGTTAAGTGGCACGGTGG	PLEK2	ENSG00000100558	0.1783035219832874	[691]	[479,118,247]	1	hSpCas9	negative selection	9716987
67392824	67392847	14	+	27869803	ASPC1	viability after 36 days	GATGAGCCAGTCCACCAGGGAGG	PLEK2	ENSG00000100558	0.47815341299774616	[290]	[143,132,144]	5	hSpCas9	negative selection	9716988
67393206	67393229	14	-	27869803	ASPC1	viability after 36 days	AAGATGCACGATAGCAACACCGG	PLEK2	ENSG00000100558	-0.4922335023601287	[630]	[124,191,148]	-5	hSpCas9	negative selection	9716989
67395466	67395489	14	-	27869803	ASPC1	viability after 36 days	GGCTATTCATGCAGGGCAGCCGG	PLEK2	ENSG00000100558	0.6322120085615882	[309]	[176,64,240]	6	hSpCas9	negative selection	9716990
67397712	67397735	14	+	27869803	ASPC1	viability after 36 days	GGAGGATCCGGCCCTTGGGAGGG	PLEK2	ENSG00000100558	-0.34021797884679206	[267]	[48,153,26]	-3	hSpCas9	negative selection	9716991
67390698	67390721	14	-	27869803	PATU8988S	viability after 35 days	GCGTCGCTTTGTTCTAAGGAAGG	PLEK2	ENSG00000100558	0.4606449300191703	[819]	[446,461,NaN]	5	hSpCas9	negative selection	9799435
67392352	67392375	14	-	27869803	PATU8988S	viability after 35 days	TGTGGAGTTAAGTGGCACGGTGG	PLEK2	ENSG00000100558	-0.14172736888395795	[533]	[170,218,NaN]	-1	hSpCas9	negative selection	9799436
67392824	67392847	14	+	27869803	PATU8988S	viability after 35 days	GATGAGCCAGTCCACCAGGGAGG	PLEK2	ENSG00000100558	-0.4524269784516137	[276]	[94,67,NaN]	-5	hSpCas9	negative selection	9799437
67393206	67393229	14	-	27869803	PATU8988S	viability after 35 days	AAGATGCACGATAGCAACACCGG	PLEK2	ENSG00000100558	-0.23304615179625868	[743]	[232,276,NaN]	-2	hSpCas9	negative selection	9799438
67395466	67395489	14	-	27869803	PATU8988S	viability after 35 days	GGCTATTCATGCAGGGCAGCCGG	PLEK2	ENSG00000100558	-0.2871403126700254	[352]	[121,110,NaN]	-3	hSpCas9	negative selection	9799439
67397712	67397735	14	+	27869803	PATU8988S	viability after 35 days	GGAGGATCCGGCCCTTGGGAGGG	PLEK2	ENSG00000100558	-0.48897212624561726	[262]	[63,86,NaN]	-5	hSpCas9	negative selection	9799440
67390698	67390721	14	-	27869803	PATU8988S	viability after 31 days	GCGTCGCTTTGTTCTAAGGAAGG	PLEK2	ENSG00000100558	0.2373407533939108	[819]	[373,399,NaN]	3	hSpCas9	negative selection	9881884
67392352	67392375	14	-	27869803	PATU8988S	viability after 31 days	TGTGGAGTTAAGTGGCACGGTGG	PLEK2	ENSG00000100558	0.30004308169176747	[533]	[233,297,NaN]	4	hSpCas9	negative selection	9881885
67392824	67392847	14	+	27869803	PATU8988S	viability after 31 days	GATGAGCCAGTCCACCAGGGAGG	PLEK2	ENSG00000100558	-1.1657048147378506	[276]	[17,88,NaN]	-8	hSpCas9	negative selection	9881886
67393206	67393229	14	-	27869803	PATU8988S	viability after 31 days	AAGATGCACGATAGCAACACCGG	PLEK2	ENSG00000100558	-0.03290662322331234	[743]	[168,443,NaN]	0	hSpCas9	negative selection	9881887
67395466	67395489	14	-	27869803	PATU8988S	viability after 31 days	GGCTATTCATGCAGGGCAGCCGG	PLEK2	ENSG00000100558	0.07780156682986417	[352]	[126,175,NaN]	1	hSpCas9	negative selection	9881888
67397712	67397735	14	+	27869803	PATU8988S	viability after 31 days	GGAGGATCCGGCCCTTGGGAGGG	PLEK2	ENSG00000100558	-0.42261064266531845	[262]	[79,75,NaN]	-5	hSpCas9	negative selection	9881889
67390698	67390721	14	-	27869803	HPAFII	viability after 35 days	GCGTCGCTTTGTTCTAAGGAAGG	PLEK2	ENSG00000100558	-0.12653837155673425	[359]	[173,158,NaN]	-1	hSpCas9	negative selection	9964333
67392352	67392375	14	-	27869803	HPAFII	viability after 35 days	TGTGGAGTTAAGTGGCACGGTGG	PLEK2	ENSG00000100558	0.13441258145026308	[166]	[160,15,NaN]	0	hSpCas9	negative selection	9964334
67392824	67392847	14	+	27869803	HPAFII	viability after 35 days	GATGAGCCAGTCCACCAGGGAGG	PLEK2	ENSG00000100558	-1.1891654491951593	[87]	[35,0,NaN]	-6	hSpCas9	negative selection	9964335
67393206	67393229	14	-	27869803	HPAFII	viability after 35 days	AAGATGCACGATAGCAACACCGG	PLEK2	ENSG00000100558	-0.8661849519097392	[366]	[68,138,NaN]	-5	hSpCas9	negative selection	9964336
67395466	67395489	14	-	27869803	HPAFII	viability after 35 days	GGCTATTCATGCAGGGCAGCCGG	PLEK2	ENSG00000100558	-0.16740837798280972	[145]	[46,86,NaN]	-1	hSpCas9	negative selection	9964337
67397712	67397735	14	+	27869803	HPAFII	viability after 35 days	GGAGGATCCGGCCCTTGGGAGGG	PLEK2	ENSG00000100558	-0.11267388132071687	[106]	[11,92,NaN]	0	hSpCas9	negative selection	9964338
67390698	67390721	14	-	27869803	HPAFII	viability after 31 days	GCGTCGCTTTGTTCTAAGGAAGG	PLEK2	ENSG00000100558	0.311788370867491	[359]	[189,316,NaN]	2	hSpCas9	negative selection	10046782
67392352	67392375	14	-	27869803	HPAFII	viability after 31 days	TGTGGAGTTAAGTGGCACGGTGG	PLEK2	ENSG00000100558	0.6508106392542381	[166]	[250,33,NaN]	5	hSpCas9	negative selection	10046783
67392824	67392847	14	+	27869803	HPAFII	viability after 31 days	GATGAGCCAGTCCACCAGGGAGG	PLEK2	ENSG00000100558	-0.09646254085912886	[87]	[83,4,NaN]	0	hSpCas9	negative selection	10046784
67393206	67393229	14	-	27869803	HPAFII	viability after 31 days	AAGATGCACGATAGCAACACCGG	PLEK2	ENSG00000100558	-0.6365720587383958	[366]	[53,217,NaN]	-4	hSpCas9	negative selection	10046785
67395466	67395489	14	-	27869803	HPAFII	viability after 31 days	GGCTATTCATGCAGGGCAGCCGG	PLEK2	ENSG00000100558	0.5798480519117765	[145]	[132,110,NaN]	4	hSpCas9	negative selection	10046786
67397712	67397735	14	+	27869803	HPAFII	viability after 31 days	GGAGGATCCGGCCCTTGGGAGGG	PLEK2	ENSG00000100558	0.4081534153574562	[106]	[27,135,NaN]	3	hSpCas9	negative selection	10046787
67397719	67397742	14	-	28162770	P31FUJ	viability	GAGTGACCCCTCCCAAGGGCCGG	PLEK2	ENSG00000100558	0.44686472025363916	[112]	[180]	5	hSpCas9	negative selection	10212633
67412017	67412040	14	-	28162770	P31FUJ	viability	GGAGGGCTTCCTGGTCAAGAGGG	PLEK2	ENSG00000100558	0.5896596100334339	[284]	[503]	6	hSpCas9	negative selection	10212634
67392824	67392847	14	+	28162770	P31FUJ	viability	GATGAGCCAGTCCACCAGGGAGG	PLEK2	ENSG00000100558	0.15778225113992606	[356]	[467]	1	hSpCas9	negative selection	10212635
67412049	67412072	14	-	28162770	P31FUJ	viability	GCGGGCGGCGACATGGAGGACGG	PLEK2	ENSG00000100558	0.41927449216531465	[55]	[87]	5	hSpCas9	negative selection	10212636
67412035	67412058	14	-	28162770	P31FUJ	viability	GGAGGACGGCGTGCTCAAGGAGG	PLEK2	ENSG00000100558	1.1949205544955805	[183]	[494]	9	hSpCas9	negative selection	10212637
67397712	67397735	14	+	28162770	P31FUJ	viability	GGAGGATCCGGCCCTTGGGAGGG	PLEK2	ENSG00000100558	-0.12885124037547036	[347]	[373]	-1	hSpCas9	negative selection	10212638
67395533	67395556	14	+	28162770	P31FUJ	viability	GGCCTCCAGGAAGTACTCCGTGG	PLEK2	ENSG00000100558	0.15734411932275438	[379]	[497]	1	hSpCas9	negative selection	10212639
67392352	67392375	14	-	28162770	P31FUJ	viability	TGTGGAGTTAAGTGGCACGGTGG	PLEK2	ENSG00000100558	0.19963834112591028	[411]	[555]	2	hSpCas9	negative selection	10212640
67390698	67390721	14	-	28162770	P31FUJ	viability	GCGTCGCTTTGTTCTAAGGAAGG	PLEK2	ENSG00000100558	0.5868883119955037	[182]	[322]	6	hSpCas9	negative selection	10212641
67388284	67388307	14	-	28162770	P31FUJ	viability	ACAGGAAGAGAACAGGCCAGTGG	PLEK2	ENSG00000100558	0.39953355456888384	[688]	[1067]	4	hSpCas9	negative selection	10212642
67397719	67397742	14	-	28162770	TF1	viability	GAGTGACCCCTCCCAAGGGCCGG	PLEK2	ENSG00000100558	NaN	[NaN]	[63]	1	hSpCas9	negative selection	10381999
67412017	67412040	14	-	28162770	TF1	viability	GGAGGGCTTCCTGGTCAAGAGGG	PLEK2	ENSG00000100558	NaN	[NaN]	[309]	1	hSpCas9	negative selection	10382000
67392824	67392847	14	+	28162770	TF1	viability	GATGAGCCAGTCCACCAGGGAGG	PLEK2	ENSG00000100558	NaN	[NaN]	[256]	1	hSpCas9	negative selection	10382001
67412049	67412072	14	-	28162770	TF1	viability	GCGGGCGGCGACATGGAGGACGG	PLEK2	ENSG00000100558	NaN	[NaN]	[30]	1	hSpCas9	negative selection	10382002
67412035	67412058	14	-	28162770	TF1	viability	GGAGGACGGCGTGCTCAAGGAGG	PLEK2	ENSG00000100558	NaN	[NaN]	[235]	1	hSpCas9	negative selection	10382003
67397712	67397735	14	+	28162770	TF1	viability	GGAGGATCCGGCCCTTGGGAGGG	PLEK2	ENSG00000100558	NaN	[NaN]	[173]	1	hSpCas9	negative selection	10382004
67395533	67395556	14	+	28162770	TF1	viability	GGCCTCCAGGAAGTACTCCGTGG	PLEK2	ENSG00000100558	NaN	[NaN]	[332]	1	hSpCas9	negative selection	10382005
67392352	67392375	14	-	28162770	TF1	viability	TGTGGAGTTAAGTGGCACGGTGG	PLEK2	ENSG00000100558	NaN	[NaN]	[333]	1	hSpCas9	negative selection	10382006
67390698	67390721	14	-	28162770	TF1	viability	GCGTCGCTTTGTTCTAAGGAAGG	PLEK2	ENSG00000100558	NaN	[NaN]	[96]	1	hSpCas9	negative selection	10382007
67388284	67388307	14	-	28162770	TF1	viability	ACAGGAAGAGAACAGGCCAGTGG	PLEK2	ENSG00000100558	NaN	[NaN]	[392]	1	hSpCas9	negative selection	10382008
67397719	67397742	14	-	28162770	SKM1	viability	GAGTGACCCCTCCCAAGGGCCGG	PLEK2	ENSG00000100558	0.1779983019779945	[29]	[59]	1	hSpCas9	negative selection	10551365
67412017	67412040	14	-	28162770	SKM1	viability	GGAGGGCTTCCTGGTCAAGAGGG	PLEK2	ENSG00000100558	-0.5370247393075347	[86]	[105]	-4	hSpCas9	negative selection	10551366
67392824	67392847	14	+	28162770	SKM1	viability	GATGAGCCAGTCCACCAGGGAGG	PLEK2	ENSG00000100558	-0.20472147702812082	[102]	[157]	-2	hSpCas9	negative selection	10551367
67412049	67412072	14	-	28162770	SKM1	viability	GCGGGCGGCGACATGGAGGACGG	PLEK2	ENSG00000100558	-0.8220016980220055	[22]	[22]	-6	hSpCas9	negative selection	10551368
67412035	67412058	14	-	28162770	SKM1	viability	GGAGGACGGCGTGCTCAAGGAGG	PLEK2	ENSG00000100558	0.8820134743429138	[61]	[201]	8	hSpCas9	negative selection	10551369
67397712	67397735	14	+	28162770	SKM1	viability	GGAGGATCCGGCCCTTGGGAGGG	PLEK2	ENSG00000100558	-0.2484439605730987	[126]	[188]	-2	hSpCas9	negative selection	10551370
67395533	67395556	14	+	28162770	SKM1	viability	GGCCTCCAGGAAGTACTCCGTGG	PLEK2	ENSG00000100558	0.7243579634754032	[100]	[294]	7	hSpCas9	negative selection	10551371
67392352	67392375	14	-	28162770	SKM1	viability	TGTGGAGTTAAGTGGCACGGTGG	PLEK2	ENSG00000100558	0.49617426200424936	[76]	[191]	5	hSpCas9	negative selection	10551372
67390698	67390721	14	-	28162770	SKM1	viability	GCGTCGCTTTGTTCTAAGGAAGG	PLEK2	ENSG00000100558	0.7752391324775874	[38]	[117]	7	hSpCas9	negative selection	10551373
67388284	67388307	14	-	28162770	SKM1	viability	ACAGGAAGAGAACAGGCCAGTGG	PLEK2	ENSG00000100558	0.6185708933639757	[139]	[379]	6	hSpCas9	negative selection	10551374
67397719	67397742	14	-	28162770	SKM1	viability	GAGTGACCCCTCCCAAGGGCCGG	PLEK2	ENSG00000100558	0.1779983019779945	[29]	[59]	1	hSpCas9	negative selection	10720731
67412017	67412040	14	-	28162770	SKM1	viability	GGAGGGCTTCCTGGTCAAGAGGG	PLEK2	ENSG00000100558	-0.5370247393075347	[86]	[105]	-4	hSpCas9	negative selection	10720732
67392824	67392847	14	+	28162770	SKM1	viability	GATGAGCCAGTCCACCAGGGAGG	PLEK2	ENSG00000100558	-0.20472147702812082	[102]	[157]	-2	hSpCas9	negative selection	10720733
67412049	67412072	14	-	28162770	SKM1	viability	GCGGGCGGCGACATGGAGGACGG	PLEK2	ENSG00000100558	-0.8220016980220055	[22]	[22]	-6	hSpCas9	negative selection	10720734
67412035	67412058	14	-	28162770	SKM1	viability	GGAGGACGGCGTGCTCAAGGAGG	PLEK2	ENSG00000100558	0.8820134743429138	[61]	[201]	8	hSpCas9	negative selection	10720735
67397712	67397735	14	+	28162770	SKM1	viability	GGAGGATCCGGCCCTTGGGAGGG	PLEK2	ENSG00000100558	-0.2484439605730987	[126]	[188]	-2	hSpCas9	negative selection	10720736
67395533	67395556	14	+	28162770	SKM1	viability	GGCCTCCAGGAAGTACTCCGTGG	PLEK2	ENSG00000100558	0.7243579634754032	[100]	[294]	7	hSpCas9	negative selection	10720737
67392352	67392375	14	-	28162770	SKM1	viability	TGTGGAGTTAAGTGGCACGGTGG	PLEK2	ENSG00000100558	0.49617426200424936	[76]	[191]	5	hSpCas9	negative selection	10720738
67390698	67390721	14	-	28162770	SKM1	viability	GCGTCGCTTTGTTCTAAGGAAGG	PLEK2	ENSG00000100558	0.7752391324775874	[38]	[117]	7	hSpCas9	negative selection	10720739
67388284	67388307	14	-	28162770	SKM1	viability	ACAGGAAGAGAACAGGCCAGTGG	PLEK2	ENSG00000100558	0.6185708933639757	[139]	[379]	6	hSpCas9	negative selection	10720740
67397719	67397742	14	-	28162770	PL21	viability	GAGTGACCCCTCCCAAGGGCCGG	PLEK2	ENSG00000100558	0.9371052086555263	[89]	[74]	7	hSpCas9	negative selection	10890097
67412017	67412040	14	-	28162770	PL21	viability	GGAGGGCTTCCTGGTCAAGAGGG	PLEK2	ENSG00000100558	1.0326828686377574	[218]	[194]	8	hSpCas9	negative selection	10890098
67392824	67392847	14	+	28162770	PL21	viability	GATGAGCCAGTCCACCAGGGAGG	PLEK2	ENSG00000100558	0.31390848944689465	[389]	[210]	2	hSpCas9	negative selection	10890099
67412049	67412072	14	-	28162770	PL21	viability	GCGGGCGGCGACATGGAGGACGG	PLEK2	ENSG00000100558	-1.4628253982331092	[37]	[5]	-7	hSpCas9	negative selection	10890100
67412035	67412058	14	-	28162770	PL21	viability	GGAGGACGGCGTGCTCAAGGAGG	PLEK2	ENSG00000100558	-1.5712360104627174	[197]	[28]	-7	hSpCas9	negative selection	10890101
67397712	67397735	14	+	28162770	PL21	viability	GGAGGATCCGGCCCTTGGGAGGG	PLEK2	ENSG00000100558	-1.1613168445846798	[369]	[71]	-7	hSpCas9	negative selection	10890102
67395533	67395556	14	+	28162770	PL21	viability	GGCCTCCAGGAAGTACTCCGTGG	PLEK2	ENSG00000100558	0.8343150896891525	[316]	[245]	7	hSpCas9	negative selection	10890103
67392352	67392375	14	-	28162770	PL21	viability	TGTGGAGTTAAGTGGCACGGTGG	PLEK2	ENSG00000100558	-0.7473929656165443	[269]	[69]	-5	hSpCas9	negative selection	10890104
67390698	67390721	14	-	28162770	PL21	viability	GCGTCGCTTTGTTCTAAGGAAGG	PLEK2	ENSG00000100558	1.2907421632702267	[107]	[114]	9	hSpCas9	negative selection	10890105
67388284	67388307	14	-	28162770	PL21	viability	ACAGGAAGAGAACAGGCCAGTGG	PLEK2	ENSG00000100558	0.5859794731968755	[573]	[374]	5	hSpCas9	negative selection	10890106
67397719	67397742	14	-	28162770	P31FUJ	viability	GAGTGACCCCTCCCAAGGGCCGG	PLEK2	ENSG00000100558	0.44686472025363916	[112]	[180]	5	hSpCas9	negative selection	11059463
67412017	67412040	14	-	28162770	P31FUJ	viability	GGAGGGCTTCCTGGTCAAGAGGG	PLEK2	ENSG00000100558	0.5896596100334339	[284]	[503]	6	hSpCas9	negative selection	11059464
67392824	67392847	14	+	28162770	P31FUJ	viability	GATGAGCCAGTCCACCAGGGAGG	PLEK2	ENSG00000100558	0.15778225113992606	[356]	[467]	1	hSpCas9	negative selection	11059465
67412049	67412072	14	-	28162770	P31FUJ	viability	GCGGGCGGCGACATGGAGGACGG	PLEK2	ENSG00000100558	0.41927449216531465	[55]	[87]	5	hSpCas9	negative selection	11059466
67412035	67412058	14	-	28162770	P31FUJ	viability	GGAGGACGGCGTGCTCAAGGAGG	PLEK2	ENSG00000100558	1.1949205544955805	[183]	[494]	9	hSpCas9	negative selection	11059467
67397712	67397735	14	+	28162770	P31FUJ	viability	GGAGGATCCGGCCCTTGGGAGGG	PLEK2	ENSG00000100558	-0.12885124037547036	[347]	[373]	-1	hSpCas9	negative selection	11059468
67395533	67395556	14	+	28162770	P31FUJ	viability	GGCCTCCAGGAAGTACTCCGTGG	PLEK2	ENSG00000100558	0.15734411932275438	[379]	[497]	1	hSpCas9	negative selection	11059469
67392352	67392375	14	-	28162770	P31FUJ	viability	TGTGGAGTTAAGTGGCACGGTGG	PLEK2	ENSG00000100558	0.19963834112591028	[411]	[555]	2	hSpCas9	negative selection	11059470
67390698	67390721	14	-	28162770	P31FUJ	viability	GCGTCGCTTTGTTCTAAGGAAGG	PLEK2	ENSG00000100558	0.5868883119955037	[182]	[322]	6	hSpCas9	negative selection	11059471
67388284	67388307	14	-	28162770	P31FUJ	viability	ACAGGAAGAGAACAGGCCAGTGG	PLEK2	ENSG00000100558	0.39953355456888384	[688]	[1067]	4	hSpCas9	negative selection	11059472
67397719	67397742	14	-	28162770	OCIAML5	viability	GAGTGACCCCTCCCAAGGGCCGG	PLEK2	ENSG00000100558	-2.1739946657513594	[54]	[21]	-8	hSpCas9	negative selection	11228829
67412017	67412040	14	-	28162770	OCIAML5	viability	GGAGGGCTTCCTGGTCAAGAGGG	PLEK2	ENSG00000100558	0.5277055985956498	[175]	[457]	4	hSpCas9	negative selection	11228830
67392824	67392847	14	+	28162770	OCIAML5	viability	GATGAGCCAGTCCACCAGGGAGG	PLEK2	ENSG00000100558	0.4651749090490287	[184]	[460]	4	hSpCas9	negative selection	11228831
67412049	67412072	14	-	28162770	OCIAML5	viability	GCGGGCGGCGACATGGAGGACGG	PLEK2	ENSG00000100558	-0.03847969509487825	[32]	[57]	0	hSpCas9	negative selection	11228832
67412035	67412058	14	-	28162770	OCIAML5	viability	GGAGGACGGCGTGCTCAAGGAGG	PLEK2	ENSG00000100558	0.42387531874918516	[101]	[246]	3	hSpCas9	negative selection	11228833
67397712	67397735	14	+	28162770	OCIAML5	viability	GGAGGATCCGGCCCTTGGGAGGG	PLEK2	ENSG00000100558	0.22939752976489935	[240]	[509]	2	hSpCas9	negative selection	11228834
67395533	67395556	14	+	28162770	OCIAML5	viability	GGCCTCCAGGAAGTACTCCGTGG	PLEK2	ENSG00000100558	0.8054645558078043	[167]	[529]	7	hSpCas9	negative selection	11228835
67392352	67392375	14	-	28162770	OCIAML5	viability	TGTGGAGTTAAGTGGCACGGTGG	PLEK2	ENSG00000100558	-0.31601367062378705	[219]	[318]	-2	hSpCas9	negative selection	11228836
67390698	67390721	14	-	28162770	OCIAML5	viability	GCGTCGCTTTGTTCTAAGGAAGG	PLEK2	ENSG00000100558	0.8743039080630101	[122]	[406]	7	hSpCas9	negative selection	11228837
67388284	67388307	14	-	28162770	OCIAML5	viability	ACAGGAAGAGAACAGGCCAGTGG	PLEK2	ENSG00000100558	0.31625454487572546	[399]	[898]	2	hSpCas9	negative selection	11228838
67397719	67397742	14	-	28162770	EOL1	viability	GAGTGACCCCTCCCAAGGGCCGG	PLEK2	ENSG00000100558	1.6521755011574046	[185]	[307]	9	hSpCas9	negative selection	11398195
67412017	67412040	14	-	28162770	EOL1	viability	GGAGGGCTTCCTGGTCAAGAGGG	PLEK2	ENSG00000100558	0.6290918880443634	[296]	[241]	5	hSpCas9	negative selection	11398196
67392824	67392847	14	+	28162770	EOL1	viability	GATGAGCCAGTCCACCAGGGAGG	PLEK2	ENSG00000100558	-0.0217835636358803	[685]	[355]	0	hSpCas9	negative selection	11398197
67412049	67412072	14	-	28162770	EOL1	viability	GCGGGCGGCGACATGGAGGACGG	PLEK2	ENSG00000100558	1.4246213747051777	[69]	[98]	9	hSpCas9	negative selection	11398198
67412035	67412058	14	-	28162770	EOL1	viability	GGAGGACGGCGTGCTCAAGGAGG	PLEK2	ENSG00000100558	0.7578979021610834	[384]	[342]	6	hSpCas9	negative selection	11398199
67397712	67397735	14	+	28162770	EOL1	viability	GGAGGATCCGGCCCTTGGGAGGG	PLEK2	ENSG00000100558	1.097069884498886	[739]	[833]	8	hSpCas9	negative selection	11398200
67395533	67395556	14	+	28162770	EOL1	viability	GGCCTCCAGGAAGTACTCCGTGG	PLEK2	ENSG00000100558	-0.07845471659098868	[480]	[239]	0	hSpCas9	negative selection	11398201
67392352	67392375	14	-	28162770	EOL1	viability	TGTGGAGTTAAGTGGCACGGTGG	PLEK2	ENSG00000100558	-0.6134936817631289	[362]	[124]	-4	hSpCas9	negative selection	11398202
67390698	67390721	14	-	28162770	EOL1	viability	GCGTCGCTTTGTTCTAAGGAAGG	PLEK2	ENSG00000100558	1.971545251107704	[150]	[311]	9	hSpCas9	negative selection	11398203
67388284	67388307	14	-	28162770	EOL1	viability	ACAGGAAGAGAACAGGCCAGTGG	PLEK2	ENSG00000100558	0.709880643343314	[744]	[641]	6	hSpCas9	negative selection	11398204
67397719	67397742	14	-	28162770	MOLM13	viability	GAGTGACCCCTCCCAAGGGCCGG	PLEK2	ENSG00000100558	-1.3621856170131088	[159]	[44]	-6	hSpCas9	negative selection	11567561
67412017	67412040	14	-	28162770	MOLM13	viability	GGAGGGCTTCCTGGTCAAGAGGG	PLEK2	ENSG00000100558	-0.3604251591486716	[363]	[204]	-2	hSpCas9	negative selection	11567562
67392824	67392847	14	+	28162770	MOLM13	viability	GATGAGCCAGTCCACCAGGGAGG	PLEK2	ENSG00000100558	-0.26187044288877537	[465]	[280]	-2	hSpCas9	negative selection	11567563
67412049	67412072	14	-	28162770	MOLM13	viability	GCGGGCGGCGACATGGAGGACGG	PLEK2	ENSG00000100558	-1.4989437545202218	[85]	[21]	-6	hSpCas9	negative selection	11567564
67412035	67412058	14	-	28162770	MOLM13	viability	GGAGGACGGCGTGCTCAAGGAGG	PLEK2	ENSG00000100558	0.32891296839576833	[293]	[266]	2	hSpCas9	negative selection	11567565
67397712	67397735	14	+	28162770	MOLM13	viability	GGAGGATCCGGCCCTTGGGAGGG	PLEK2	ENSG00000100558	0.07361044243253234	[505]	[384]	0	hSpCas9	negative selection	11567566
67395533	67395556	14	+	28162770	MOLM13	viability	GGCCTCCAGGAAGTACTCCGTGG	PLEK2	ENSG00000100558	0.1423590499770211	[400]	[319]	1	hSpCas9	negative selection	11567567
67392352	67392375	14	-	28162770	MOLM13	viability	TGTGGAGTTAAGTGGCACGGTGG	PLEK2	ENSG00000100558	0.4534982892389571	[402]	[398]	3	hSpCas9	negative selection	11567568
67390698	67390721	14	-	28162770	MOLM13	viability	GCGTCGCTTTGTTCTAAGGAAGG	PLEK2	ENSG00000100558	-0.7687168990115698	[237]	[100]	-4	hSpCas9	negative selection	11567569
67388284	67388307	14	-	28162770	MOLM13	viability	ACAGGAAGAGAACAGGCCAGTGG	PLEK2	ENSG00000100558	0.19720617697580733	[642]	[532]	1	hSpCas9	negative selection	11567570
67397719	67397742	14	-	28162770	HEL	viability	GAGTGACCCCTCCCAAGGGCCGG	PLEK2	ENSG00000100558	0.7477083916018995	[158]	[170]	6	hSpCas9	negative selection	11736927
67412017	67412040	14	-	28162770	HEL	viability	GGAGGGCTTCCTGGTCAAGAGGG	PLEK2	ENSG00000100558	-0.04376169518286144	[308]	[191]	0	hSpCas9	negative selection	11736928
67392824	67392847	14	+	28162770	HEL	viability	GATGAGCCAGTCCACCAGGGAGG	PLEK2	ENSG00000100558	0.3716349961906771	[501]	[415]	3	hSpCas9	negative selection	11736929
67412049	67412072	14	-	28162770	HEL	viability	GCGGGCGGCGACATGGAGGACGG	PLEK2	ENSG00000100558	1.196939078950826	[78]	[115]	9	hSpCas9	negative selection	11736930
67412035	67412058	14	-	28162770	HEL	viability	GGAGGACGGCGTGCTCAAGGAGG	PLEK2	ENSG00000100558	-0.0799953763251897	[268]	[162]	0	hSpCas9	negative selection	11736931
67397712	67397735	14	+	28162770	HEL	viability	GGAGGATCCGGCCCTTGGGAGGG	PLEK2	ENSG00000100558	0.6045195097698667	[458]	[446]	5	hSpCas9	negative selection	11736932
67395533	67395556	14	+	28162770	HEL	viability	GGCCTCCAGGAAGTACTCCGTGG	PLEK2	ENSG00000100558	1.1906706017765463	[341]	[499]	9	hSpCas9	negative selection	11736933
67392352	67392375	14	-	28162770	HEL	viability	TGTGGAGTTAAGTGGCACGGTGG	PLEK2	ENSG00000100558	0.5252155285178641	[293]	[270]	4	hSpCas9	negative selection	11736934
67390698	67390721	14	-	28162770	HEL	viability	GCGTCGCTTTGTTCTAAGGAAGG	PLEK2	ENSG00000100558	-0.5510329113963233	[182]	[79]	-4	hSpCas9	negative selection	11736935
67388284	67388307	14	-	28162770	HEL	viability	ACAGGAAGAGAACAGGCCAGTGG	PLEK2	ENSG00000100558	-0.34304730877994216	[605]	[305]	-2	hSpCas9	negative selection	11736936
67397719	67397742	14	-	28162770	MV411	viability	GAGTGACCCCTCCCAAGGGCCGG	PLEK2	ENSG00000100558	0.14274017211608203	[99]	[92]	1	hSpCas9	negative selection	11906293
67412017	67412040	14	-	28162770	MV411	viability	GGAGGGCTTCCTGGTCAAGAGGG	PLEK2	ENSG00000100558	0.44078143960872485	[257]	[294]	4	hSpCas9	negative selection	11906294
67392824	67392847	14	+	28162770	MV411	viability	GATGAGCCAGTCCACCAGGGAGG	PLEK2	ENSG00000100558	0.6023944460576085	[379]	[485]	5	hSpCas9	negative selection	11906295
67412049	67412072	14	-	28162770	MV411	viability	GCGGGCGGCGACATGGAGGACGG	PLEK2	ENSG00000100558	-0.05866557694290431	[67]	[54]	0	hSpCas9	negative selection	11906296
67412035	67412058	14	-	28162770	MV411	viability	GGAGGACGGCGTGCTCAAGGAGG	PLEK2	ENSG00000100558	-0.20786381870979553	[217]	[158]	-1	hSpCas9	negative selection	11906297
67397712	67397735	14	+	28162770	MV411	viability	GGAGGATCCGGCCCTTGGGAGGG	PLEK2	ENSG00000100558	0.06529873936440667	[429]	[378]	0	hSpCas9	negative selection	11906298
67395533	67395556	14	+	28162770	MV411	viability	GGCCTCCAGGAAGTACTCCGTGG	PLEK2	ENSG00000100558	-0.45422117464747835	[295]	[181]	-3	hSpCas9	negative selection	11906299
67392352	67392375	14	-	28162770	MV411	viability	TGTGGAGTTAAGTGGCACGGTGG	PLEK2	ENSG00000100558	1.0082498869033492	[215]	[365]	8	hSpCas9	negative selection	11906300
67390698	67390721	14	-	28162770	MV411	viability	GCGTCGCTTTGTTCTAAGGAAGG	PLEK2	ENSG00000100558	0.4153821880968467	[161]	[181]	3	hSpCas9	negative selection	11906301
67388284	67388307	14	-	28162770	MV411	viability	ACAGGAAGAGAACAGGCCAGTGG	PLEK2	ENSG00000100558	0.568126749036779	[465]	[581]	5	hSpCas9	negative selection	11906302
67397719	67397742	14	-	28162770	MONOMAC1	viability	GAGTGACCCCTCCCAAGGGCCGG	PLEK2	ENSG00000100558	-0.2685901080845876	[61]	[58]	-2	hSpCas9	negative selection	12075659
67412017	67412040	14	-	28162770	MONOMAC1	viability	GGAGGGCTTCCTGGTCAAGAGGG	PLEK2	ENSG00000100558	0.40810353559923274	[141]	[215]	4	hSpCas9	negative selection	12075660
67392824	67392847	14	+	28162770	MONOMAC1	viability	GATGAGCCAGTCCACCAGGGAGG	PLEK2	ENSG00000100558	-0.5734127259692927	[269]	[207]	-5	hSpCas9	negative selection	12075661
67412049	67412072	14	-	28162770	MONOMAC1	viability	GCGGGCGGCGACATGGAGGACGG	PLEK2	ENSG00000100558	0.6330381514981338	[26]	[47]	6	hSpCas9	negative selection	12075662
67412035	67412058	14	-	28162770	MONOMAC1	viability	GGAGGACGGCGTGCTCAAGGAGG	PLEK2	ENSG00000100558	1.023769323384943	[129]	[302]	8	hSpCas9	negative selection	12075663
67397712	67397735	14	+	28162770	MONOMAC1	viability	GGAGGATCCGGCCCTTGGGAGGG	PLEK2	ENSG00000100558	0.9010352757283737	[262]	[562]	8	hSpCas9	negative selection	12075664
67395533	67395556	14	+	28162770	MONOMAC1	viability	GGCCTCCAGGAAGTACTCCGTGG	PLEK2	ENSG00000100558	1.031781843436327	[191]	[449]	8	hSpCas9	negative selection	12075665
67392352	67392375	14	-	28162770	MONOMAC1	viability	TGTGGAGTTAAGTGGCACGGTGG	PLEK2	ENSG00000100558	0.38792565366160237	[181]	[272]	4	hSpCas9	negative selection	12075666
67390698	67390721	14	-	28162770	MONOMAC1	viability	GCGTCGCTTTGTTCTAAGGAAGG	PLEK2	ENSG00000100558	0.8299302005407156	[105]	[215]	7	hSpCas9	negative selection	12075667
67388284	67388307	14	-	28162770	MONOMAC1	viability	ACAGGAAGAGAACAGGCCAGTGG	PLEK2	ENSG00000100558	0.6866390349732145	[354]	[654]	6	hSpCas9	negative selection	12075668
67397719	67397742	14	-	28162770	OCIAML2	viability	GAGTGACCCCTCCCAAGGGCCGG	PLEK2	ENSG00000100558	-0.4556794837761897	[23]	[96]	-4	hSpCas9	negative selection	12245025
67412017	67412040	14	-	28162770	OCIAML2	viability	GGAGGGCTTCCTGGTCAAGAGGG	PLEK2	ENSG00000100558	-0.5463571514054062	[43]	[166]	-4	hSpCas9	negative selection	12245026
67392824	67392847	14	+	28162770	OCIAML2	viability	GATGAGCCAGTCCACCAGGGAGG	PLEK2	ENSG00000100558	0.3089801063325387	[59]	[411]	3	hSpCas9	negative selection	12245027
67412049	67412072	14	-	28162770	OCIAML2	viability	GCGGGCGGCGACATGGAGGACGG	PLEK2	ENSG00000100558	-1.553091985434134	[8]	[16]	-7	hSpCas9	negative selection	12245028
67412035	67412058	14	-	28162770	OCIAML2	viability	GGAGGACGGCGTGCTCAAGGAGG	PLEK2	ENSG00000100558	0.0814680415733683	[36]	[216]	0	hSpCas9	negative selection	12245029
67397712	67397735	14	+	28162770	OCIAML2	viability	GGAGGATCCGGCCCTTGGGAGGG	PLEK2	ENSG00000100558	0.18281241336176168	[71]	[452]	1	hSpCas9	negative selection	12245030
67395533	67395556	14	+	28162770	OCIAML2	viability	GGCCTCCAGGAAGTACTCCGTGG	PLEK2	ENSG00000100558	0.21795530655315243	[46]	[302]	2	hSpCas9	negative selection	12245031
67392352	67392375	14	-	28162770	OCIAML2	viability	TGTGGAGTTAAGTGGCACGGTGG	PLEK2	ENSG00000100558	-0.3783713173901725	[52]	[225]	-3	hSpCas9	negative selection	12245032
67390698	67390721	14	-	28162770	OCIAML2	viability	GCGTCGCTTTGTTCTAAGGAAGG	PLEK2	ENSG00000100558	0.8632709113112771	[23]	[241]	8	hSpCas9	negative selection	12245033
67388284	67388307	14	-	28162770	OCIAML2	viability	ACAGGAAGAGAACAGGCCAGTGG	PLEK2	ENSG00000100558	-0.9537563143631744	[93]	[268]	-6	hSpCas9	negative selection	12245034
67397719	67397742	14	-	28162770	OCIAML3	viability	GAGTGACCCCTCCCAAGGGCCGG	PLEK2	ENSG00000100558	-0.7076644221197304	[32]	[60]	-5	hSpCas9	negative selection	12414391
67412017	67412040	14	-	28162770	OCIAML3	viability	GGAGGGCTTCCTGGTCAAGAGGG	PLEK2	ENSG00000100558	1.0736225180668275	[64]	[412]	8	hSpCas9	negative selection	12414392
67392824	67392847	14	+	28162770	OCIAML3	viability	GATGAGCCAGTCCACCAGGGAGG	PLEK2	ENSG00000100558	0.07316962368518043	[107]	[342]	0	hSpCas9	negative selection	12414393
67412049	67412072	14	-	28162770	OCIAML3	viability	GCGGGCGGCGACATGGAGGACGG	PLEK2	ENSG00000100558	-1.2154960170704332	[19]	[25]	-7	hSpCas9	negative selection	12414394
67412035	67412058	14	-	28162770	OCIAML3	viability	GGAGGACGGCGTGCTCAAGGAGG	PLEK2	ENSG00000100558	0.042301740397213405	[45]	[142]	0	hSpCas9	negative selection	12414395
67397712	67397735	14	+	28162770	OCIAML3	viability	GGAGGATCCGGCCCTTGGGAGGG	PLEK2	ENSG00000100558	-0.23075268314786557	[116]	[300]	-2	hSpCas9	negative selection	12414396
67395533	67395556	14	+	28162770	OCIAML3	viability	GGCCTCCAGGAAGTACTCCGTGG	PLEK2	ENSG00000100558	-0.25902339261135454	[87]	[221]	-2	hSpCas9	negative selection	12414397
67392352	67392375	14	-	28162770	OCIAML3	viability	TGTGGAGTTAAGTGGCACGGTGG	PLEK2	ENSG00000100558	0.15360519804155137	[80]	[271]	1	hSpCas9	negative selection	12414398
67390698	67390721	14	-	28162770	OCIAML3	viability	GCGTCGCTTTGTTCTAAGGAAGG	PLEK2	ENSG00000100558	0.683977106975602	[39]	[193]	6	hSpCas9	negative selection	12414399
67388284	67388307	14	-	28162770	OCIAML3	viability	ACAGGAAGAGAACAGGCCAGTGG	PLEK2	ENSG00000100558	0.9693845499747749	[145]	[862]	8	hSpCas9	negative selection	12414400