| 16817168 | 16817191 | 11 | - | 26472758 | Jiyoye | viability | AAGTGACTACAAGTATGCGCAGG | PLEKHA7 | ENSG00000166689 | -1.3681183313194323 | [88] | [25] | -7 | hSpCas9 | negative selection | 122079 | 16826231 | 16826254 | 11 | - | 26472758 | Jiyoye | viability | GGAGAACAGAATGGGACTGGTGG | PLEKHA7 | ENSG00000166689 | 0.08524728661851122 | [54] | [43] | 0 | hSpCas9 | negative selection | 122080 | 16816836 | 16816859 | 11 | - | 26472758 | Jiyoye | viability | GGAGTGTGGACATCTCGCTGGGG | PLEKHA7 | ENSG00000166689 | 0.7084798042673845 | [154] | [190] | 5 | hSpCas9 | negative selection | 122081 | 16854948 | 16854971 | 11 | + | 26472758 | Jiyoye | viability | GGTCTCTCTTCCCAAAGCTGTGG | PLEKHA7 | ENSG00000166689 | -0.2596983170019003 | [153] | [96] | -2 | hSpCas9 | negative selection | 122082 | 16854934 | 16854957 | 11 | - | 26472758 | Jiyoye | viability | AGAGAGACCAGGCCATTCGGAGG | PLEKHA7 | ENSG00000166689 | 1.1441409756720793 | [56] | [94] | 7 | hSpCas9 | negative selection | 122083 | 16826416 | 16826439 | 11 | - | 26472758 | Jiyoye | viability | GAGAGCAGTACCGTTCCCAGAGG | PLEKHA7 | ENSG00000166689 | 0.4612152212187625 | [130] | [135] | 3 | hSpCas9 | negative selection | 122084 | 16826157 | 16826180 | 11 | - | 26472758 | Jiyoye | viability | GAAGAGCAATCTGGCCCAGGTGG | PLEKHA7 | ENSG00000166689 | 0.2524527867072315 | [58] | [52] | 2 | hSpCas9 | negative selection | 122085 | 16975016 | 16975039 | 11 | + | 26472758 | Jiyoye | viability | TTGCGTGAGCGCTATCGGCGCGG | PLEKHA7 | ENSG00000166689 | 0.08524728661851122 | [69] | [55] | 0 | hSpCas9 | negative selection | 139495 | 16817168 | 16817191 | 11 | - | 26472758 | KBM7 | viability | AAGTGACTACAAGTATGCGCAGG | PLEKHA7 | ENSG00000166689 | -0.22283426796933314 | [204,468] | [181,105] | -2 | hSpCas9 | negative selection | 313197 | 16826231 | 16826254 | 11 | - | 26472758 | KBM7 | viability | GGAGAACAGAATGGGACTGGTGG | PLEKHA7 | ENSG00000166689 | -0.0679588929269852 | [243,180] | [87,99] | 0 | hSpCas9 | negative selection | 313198 | 16816836 | 16816859 | 11 | - | 26472758 | KBM7 | viability | GGAGTGTGGACATCTCGCTGGGG | PLEKHA7 | ENSG00000166689 | 0.009619008866469603 | [902,514] | [330,324] | 0 | hSpCas9 | negative selection | 313199 | 16854948 | 16854971 | 11 | + | 26472758 | KBM7 | viability | GGTCTCTCTTCCCAAAGCTGTGG | PLEKHA7 | ENSG00000166689 | -0.237969475877313 | [705,482] | [268,201] | -2 | hSpCas9 | negative selection | 313200 | 16854934 | 16854957 | 11 | - | 26472758 | KBM7 | viability | AGAGAGACCAGGCCATTCGGAGG | PLEKHA7 | ENSG00000166689 | -0.12081896951600718 | [444,344] | [151,184] | -1 | hSpCas9 | negative selection | 313201 | 16826416 | 16826439 | 11 | - | 26472758 | KBM7 | viability | GAGAGCAGTACCGTTCCCAGAGG | PLEKHA7 | ENSG00000166689 | 0.3882153421051076 | [517,407] | [266,296] | 4 | hSpCas9 | negative selection | 313202 | 16826157 | 16826180 | 11 | - | 26472758 | KBM7 | viability | GAAGAGCAATCTGGCCCAGGTGG | PLEKHA7 | ENSG00000166689 | 0.9128269578818604 | [245,130] | [162,161] | 8 | hSpCas9 | negative selection | 313203 | 16975016 | 16975039 | 11 | + | 26472758 | KBM7 | viability | TTGCGTGAGCGCTATCGGCGCGG | PLEKHA7 | ENSG00000166689 | 0.9256929541125198 | [170,92] | [59,163] | 8 | hSpCas9 | negative selection | 330613 | 16817168 | 16817191 | 11 | - | 26472758 | Raji | viability | AAGTGACTACAAGTATGCGCAGG | PLEKHA7 | ENSG00000166689 | 0.09408671276014169 | [108] | [26] | 0 | hSpCas9 | negative selection | 504315 | 16826231 | 16826254 | 11 | - | 26472758 | Raji | viability | GGAGAACAGAATGGGACTGGTGG | PLEKHA7 | ENSG00000166689 | -0.2645852420133583 | [87] | [16] | -2 | hSpCas9 | negative selection | 504316 | 16816836 | 16816859 | 11 | - | 26472758 | Raji | viability | GGAGTGTGGACATCTCGCTGGGG | PLEKHA7 | ENSG00000166689 | 0.23969082747772985 | [353] | [96] | 2 | hSpCas9 | negative selection | 504317 | 16854948 | 16854971 | 11 | + | 26472758 | Raji | viability | GGTCTCTCTTCCCAAAGCTGTGG | PLEKHA7 | ENSG00000166689 | 0.10359195621122541 | [380] | [94] | 1 | hSpCas9 | negative selection | 504318 | 16854934 | 16854957 | 11 | - | 26472758 | Raji | viability | AGAGAGACCAGGCCATTCGGAGG | PLEKHA7 | ENSG00000166689 | 0.5593206174639724 | [192] | [65] | 5 | hSpCas9 | negative selection | 504319 | 16826416 | 16826439 | 11 | - | 26472758 | Raji | viability | GAGAGCAGTACCGTTCCCAGAGG | PLEKHA7 | ENSG00000166689 | 0.26810384591975844 | [296] | [82] | 2 | hSpCas9 | negative selection | 504320 | 16826157 | 16826180 | 11 | - | 26472758 | Raji | viability | GAAGAGCAATCTGGCCCAGGTGG | PLEKHA7 | ENSG00000166689 | -0.6053345125459295 | [117] | [17] | -5 | hSpCas9 | negative selection | 504321 | 16975016 | 16975039 | 11 | + | 26472758 | Raji | viability | TTGCGTGAGCGCTATCGGCGCGG | PLEKHA7 | ENSG00000166689 | -0.6581512109893776 | [135] | [19] | -5 | hSpCas9 | negative selection | 521731 | 16817168 | 16817191 | 11 | - | 26472758 | K562 | viability | AAGTGACTACAAGTATGCGCAGG | PLEKHA7 | ENSG00000166689 | -0.6124563302349557 | [162] | [89] | -4 | hSpCas9 | negative selection | 695433 | 16826231 | 16826254 | 11 | - | 26472758 | K562 | viability | GGAGAACAGAATGGGACTGGTGG | PLEKHA7 | ENSG00000166689 | -0.9656164871500184 | [154] | [66] | -5 | hSpCas9 | negative selection | 695434 | 16816836 | 16816859 | 11 | - | 26472758 | K562 | viability | GGAGTGTGGACATCTCGCTGGGG | PLEKHA7 | ENSG00000166689 | 0.22500998148031814 | [448] | [442] | 1 | hSpCas9 | negative selection | 695435 | 16854948 | 16854971 | 11 | + | 26472758 | K562 | viability | GGTCTCTCTTCCCAAAGCTGTGG | PLEKHA7 | ENSG00000166689 | -0.07880268424243614 | [557] | [445] | 0 | hSpCas9 | negative selection | 695436 | 16854934 | 16854957 | 11 | - | 26472758 | K562 | viability | AGAGAGACCAGGCCATTCGGAGG | PLEKHA7 | ENSG00000166689 | -0.009497782003530214 | [346] | [290] | 0 | hSpCas9 | negative selection | 695437 | 16826416 | 16826439 | 11 | - | 26472758 | K562 | viability | GAGAGCAGTACCGTTCCCAGAGG | PLEKHA7 | ENSG00000166689 | 0.791137393247464 | [394] | [576] | 6 | hSpCas9 | negative selection | 695438 | 16826157 | 16826180 | 11 | - | 26472758 | K562 | viability | GAAGAGCAATCTGGCCCAGGTGG | PLEKHA7 | ENSG00000166689 | 1.4011442313539 | [121] | [271] | 9 | hSpCas9 | negative selection | 695439 | 16975016 | 16975039 | 11 | + | 26472758 | K562 | viability | TTGCGTGAGCGCTATCGGCGCGG | PLEKHA7 | ENSG00000166689 | 0.7903870967717395 | [99] | [145] | 6 | hSpCas9 | negative selection | 712849 | 16841617 | 16841640 | 11 | - | 26627737 | DLD1 | viability | CTACTTCAGTGCCGACACCCAGG | PLEKHA7 | ENSG00000166689 | 0.0259192162290649 | [1031] | [332,386,275] | 0 | hSpCas9 | negative selection | 777765 | 16851236 | 16851259 | 11 | + | 26627737 | DLD1 | viability | AGAGATCACGTAGCTGGGCAAGG | PLEKHA7 | ENSG00000166689 | -0.22183144014201978 | [695] | [179,274,118] | -2 | hSpCas9 | negative selection | 777766 | 16855862 | 16855885 | 11 | - | 26627737 | DLD1 | viability | AAACCAAAGACCGTCCAGCATGG | PLEKHA7 | ENSG00000166689 | -0.19867825082349921 | [1099] | [431,226,244] | -2 | hSpCas9 | negative selection | 777767 | 16841617 | 16841640 | 11 | - | 26627737 | GBM cells | viability after 5 days | CTACTTCAGTGCCGACACCCAGG | PLEKHA7 | ENSG00000166689 | 0.09616486167413685 | [429] | [266,225] | 1 | hSpCas9 | negative selection | 860080 | 16851236 | 16851259 | 11 | + | 26627737 | GBM cells | viability after 5 days | AGAGATCACGTAGCTGGGCAAGG | PLEKHA7 | ENSG00000166689 | 0.38971888178249414 | [305] | [198,230] | 6 | hSpCas9 | negative selection | 860081 | 16855862 | 16855885 | 11 | - | 26627737 | GBM cells | viability after 5 days | AAACCAAAGACCGTCCAGCATGG | PLEKHA7 | ENSG00000166689 | 0.36709414223099257 | [552] | [384,379] | 5 | hSpCas9 | negative selection | 860082 | 16841617 | 16841640 | 11 | - | 26627737 | GBM cells | viability after 13 days | CTACTTCAGTGCCGACACCCAGG | PLEKHA7 | ENSG00000166689 | 0.3287033329118053 | [429] | [233,340] | 4 | hSpCas9 | negative selection | 942395 | 16851236 | 16851259 | 11 | + | 26627737 | GBM cells | viability after 13 days | AGAGATCACGTAGCTGGGCAAGG | PLEKHA7 | ENSG00000166689 | 0.6401713299915123 | [305] | [255,260] | 7 | hSpCas9 | negative selection | 942396 | 16855862 | 16855885 | 11 | - | 26627737 | GBM cells | viability after 13 days | AAACCAAAGACCGTCCAGCATGG | PLEKHA7 | ENSG00000166689 | 0.4642494097711911 | [552] | [585,273] | 6 | hSpCas9 | negative selection | 942397 | 16841617 | 16841640 | 11 | - | 26627737 | GBM cells | viability after 21 days | CTACTTCAGTGCCGACACCCAGG | PLEKHA7 | ENSG00000166689 | -0.09434410350443467 | [429] | [222,214] | -1 | hSpCas9 | negative selection | 1024710 | 16851236 | 16851259 | 11 | + | 26627737 | GBM cells | viability after 21 days | AGAGATCACGTAGCTGGGCAAGG | PLEKHA7 | ENSG00000166689 | 1.020829010514039 | [305] | [364,311] | 8 | hSpCas9 | negative selection | 1024711 | 16855862 | 16855885 | 11 | - | 26627737 | GBM cells | viability after 21 days | AAACCAAAGACCGTCCAGCATGG | PLEKHA7 | ENSG00000166689 | -0.1453266389129746 | [552] | [279,263] | -1 | hSpCas9 | negative selection | 1024712 | 16841617 | 16841640 | 11 | - | 26627737 | RPE1 | viability after 9 days | CTACTTCAGTGCCGACACCCAGG | PLEKHA7 | ENSG00000166689 | 0.4165432753496398 | [888] | [453,264] | 3 | hSpCas9 | negative selection | 1107025 | 16851236 | 16851259 | 11 | + | 26627737 | RPE1 | viability after 9 days | AGAGATCACGTAGCTGGGCAAGG | PLEKHA7 | ENSG00000166689 | -0.2724287489804772 | [1778] | [392,548] | -2 | hSpCas9 | negative selection | 1107026 | 16855862 | 16855885 | 11 | - | 26627737 | RPE1 | viability after 9 days | AAACCAAAGACCGTCCAGCATGG | PLEKHA7 | ENSG00000166689 | 0.2933202928769578 | [2560] | [937,1039] | 2 | hSpCas9 | negative selection | 1107027 | 16841617 | 16841640 | 11 | - | 26627737 | RPE1 | viability after 12 days | CTACTTCAGTGCCGACACCCAGG | PLEKHA7 | ENSG00000166689 | -0.26351072645049745 | [888] | [282,109] | -2 | hSpCas9 | negative selection | 1189340 | 16851236 | 16851259 | 11 | + | 26627737 | RPE1 | viability after 12 days | AGAGATCACGTAGCTGGGCAAGG | PLEKHA7 | ENSG00000166689 | 0.07162504949177806 | [1778] | [511,491] | 0 | hSpCas9 | negative selection | 1189341 | 16855862 | 16855885 | 11 | - | 26627737 | RPE1 | viability after 12 days | AAACCAAAGACCGTCCAGCATGG | PLEKHA7 | ENSG00000166689 | 0.5573464220770048 | [2560] | [944,1083] | 3 | hSpCas9 | negative selection | 1189342 | 16841617 | 16841640 | 11 | - | 26627737 | RPE1 | viability after 15 days | CTACTTCAGTGCCGACACCCAGG | PLEKHA7 | ENSG00000166689 | 0.16278154042188342 | [888] | [364,200] | 1 | hSpCas9 | negative selection | 1271655 | 16851236 | 16851259 | 11 | + | 26627737 | RPE1 | viability after 15 days | AGAGATCACGTAGCTGGGCAAGG | PLEKHA7 | ENSG00000166689 | -0.09610783952901647 | [1778] | [565,378] | 0 | hSpCas9 | negative selection | 1271656 | 16855862 | 16855885 | 11 | - | 26627737 | RPE1 | viability after 15 days | AAACCAAAGACCGTCCAGCATGG | PLEKHA7 | ENSG00000166689 | 0.40348325956637376 | [2560] | [860,1051] | 2 | hSpCas9 | negative selection | 1271657 | 16841617 | 16841640 | 11 | - | 26627737 | RPE1 | viability after 18 days | CTACTTCAGTGCCGACACCCAGG | PLEKHA7 | ENSG00000166689 | -0.19659334185126337 | [888] | [204,213] | -1 | hSpCas9 | negative selection | 1353970 | 16851236 | 16851259 | 11 | + | 26627737 | RPE1 | viability after 18 days | AGAGATCACGTAGCTGGGCAAGG | PLEKHA7 | ENSG00000166689 | -0.407317760313881 | [1778] | [332,392] | -3 | hSpCas9 | negative selection | 1353971 | 16855862 | 16855885 | 11 | - | 26627737 | RPE1 | viability after 18 days | AAACCAAAGACCGTCCAGCATGG | PLEKHA7 | ENSG00000166689 | 0.6903174262701781 | [2560] | [961,1278] | 4 | hSpCas9 | negative selection | 1353972 | 16841617 | 16841640 | 11 | - | 26627737 | HeLa | viability after 8 days | CTACTTCAGTGCCGACACCCAGG | PLEKHA7 | ENSG00000166689 | -0.3377022316282806 | [796] | [287,259,277] | -3 | hSpCas9 | negative selection | 1436285 | 16851236 | 16851259 | 11 | + | 26627737 | HeLa | viability after 8 days | AGAGATCACGTAGCTGGGCAAGG | PLEKHA7 | ENSG00000166689 | 1.316227779108259 | [423] | [432,665,285] | 8 | hSpCas9 | negative selection | 1436286 | 16855862 | 16855885 | 11 | - | 26627737 | HeLa | viability after 8 days | AAACCAAAGACCGTCCAGCATGG | PLEKHA7 | ENSG00000166689 | 0.2032239998085421 | [998] | [709,403,437] | 2 | hSpCas9 | negative selection | 1436287 | 16841617 | 16841640 | 11 | - | 26627737 | HeLa | viability after 12 days | CTACTTCAGTGCCGACACCCAGG | PLEKHA7 | ENSG00000166689 | -0.29049951705179944 | [796] | [83,226,495] | -3 | hSpCas9 | negative selection | 1518600 | 16851236 | 16851259 | 11 | + | 26627737 | HeLa | viability after 12 days | AGAGATCACGTAGCTGGGCAAGG | PLEKHA7 | ENSG00000166689 | 0.6684837980772148 | [423] | [204,281,345] | 5 | hSpCas9 | negative selection | 1518601 | 16855862 | 16855885 | 11 | - | 26627737 | HeLa | viability after 12 days | AAACCAAAGACCGTCCAGCATGG | PLEKHA7 | ENSG00000166689 | 0.19562584498427804 | [998] | [499,521,391] | 1 | hSpCas9 | negative selection | 1518602 | 16841617 | 16841640 | 11 | - | 26627737 | HeLa | viability after 15 days | CTACTTCAGTGCCGACACCCAGG | PLEKHA7 | ENSG00000166689 | -0.18156442526700178 | [796] | [188,414,252] | -1 | hSpCas9 | negative selection | 1600915 | 16851236 | 16851259 | 11 | + | 26627737 | HeLa | viability after 15 days | AGAGATCACGTAGCTGGGCAAGG | PLEKHA7 | ENSG00000166689 | 0.40350199640504203 | [423] | [345,222,104] | 3 | hSpCas9 | negative selection | 1600916 | 16855862 | 16855885 | 11 | - | 26627737 | HeLa | viability after 15 days | AAACCAAAGACCGTCCAGCATGG | PLEKHA7 | ENSG00000166689 | 0.3758684397242549 | [998] | [423,566,598] | 3 | hSpCas9 | negative selection | 1600917 | 16841617 | 16841640 | 11 | - | 26627737 | HeLa | viability after 18 days | CTACTTCAGTGCCGACACCCAGG | PLEKHA7 | ENSG00000166689 | -0.19698716732238053 | [796] | [122,340,252] | -2 | hSpCas9 | negative selection | 1683230 | 16851236 | 16851259 | 11 | + | 26627737 | HeLa | viability after 18 days | AGAGATCACGTAGCTGGGCAAGG | PLEKHA7 | ENSG00000166689 | 0.4360251437224474 | [423] | [237,189,104] | 3 | hSpCas9 | negative selection | 1683231 | 16855862 | 16855885 | 11 | - | 26627737 | HeLa | viability after 18 days | AAACCAAAGACCGTCCAGCATGG | PLEKHA7 | ENSG00000166689 | 0.3565093592879156 | [998] | [275,462,598] | 3 | hSpCas9 | negative selection | 1683232 | 16841617 | 16841640 | 11 | - | 26627737 | HCT116 | viability after 6 days | CTACTTCAGTGCCGACACCCAGG | PLEKHA7 | ENSG00000166689 | -0.5590701290082081 | [769] | [47,100] | -3 | hSpCas9 | negative selection | 1765545 | 16851236 | 16851259 | 11 | + | 26627737 | HCT116 | viability after 6 days | AGAGATCACGTAGCTGGGCAAGG | PLEKHA7 | ENSG00000166689 | -0.4562073513282868 | [667] | [140,40] | -3 | hSpCas9 | negative selection | 1765546 | 16855862 | 16855885 | 11 | - | 26627737 | HCT116 | viability after 6 days | AAACCAAAGACCGTCCAGCATGG | PLEKHA7 | ENSG00000166689 | 1.1155950850605862 | [1738] | [583,596] | 6 | hSpCas9 | negative selection | 1765547 | 16841617 | 16841640 | 11 | - | 26627737 | HCT116 | viability after 8 days | CTACTTCAGTGCCGACACCCAGG | PLEKHA7 | ENSG00000166689 | -0.7919381880257121 | [657] | [174,191,259] | -7 | hSpCas9 | negative selection | 1847860 | 16851236 | 16851259 | 11 | + | 26627737 | HCT116 | viability after 8 days | AGAGATCACGTAGCTGGGCAAGG | PLEKHA7 | ENSG00000166689 | 0.43371616663681467 | [346] | [332,256,186] | 4 | hSpCas9 | negative selection | 1847861 | 16855862 | 16855885 | 11 | - | 26627737 | HCT116 | viability after 8 days | AAACCAAAGACCGTCCAGCATGG | PLEKHA7 | ENSG00000166689 | 0.33101813000789837 | [522] | [373,372,340] | 3 | hSpCas9 | negative selection | 1847862 | 16841617 | 16841640 | 11 | - | 26627737 | HCT116 | viability after 9 days | CTACTTCAGTGCCGACACCCAGG | PLEKHA7 | ENSG00000166689 | 0.5120962589486835 | [769] | [190,373] | 4 | hSpCas9 | negative selection | 1930175 | 16851236 | 16851259 | 11 | + | 26627737 | HCT116 | viability after 9 days | AGAGATCACGTAGCTGGGCAAGG | PLEKHA7 | ENSG00000166689 | 0.38653113621738777 | [667] | [221,241] | 3 | hSpCas9 | negative selection | 1930176 | 16855862 | 16855885 | 11 | - | 26627737 | HCT116 | viability after 9 days | AAACCAAAGACCGTCCAGCATGG | PLEKHA7 | ENSG00000166689 | 0.8679941479002455 | [1738] | [942,771] | 6 | hSpCas9 | negative selection | 1930177 | 16841617 | 16841640 | 11 | - | 26627737 | HCT116 | viability after 12 days | CTACTTCAGTGCCGACACCCAGG | PLEKHA7 | ENSG00000166689 | -0.3615134208994951 | [657] | [239,144,421] | -4 | hSpCas9 | negative selection | 2012490 | 16851236 | 16851259 | 11 | + | 26627737 | HCT116 | viability after 12 days | AGAGATCACGTAGCTGGGCAAGG | PLEKHA7 | ENSG00000166689 | 0.44986416255240824 | [346] | [371,188,173] | 4 | hSpCas9 | negative selection | 2012491 | 16855862 | 16855885 | 11 | - | 26627737 | HCT116 | viability after 12 days | AAACCAAAGACCGTCCAGCATGG | PLEKHA7 | ENSG00000166689 | 0.3343332977184993 | [522] | [304,377,360] | 3 | hSpCas9 | negative selection | 2012492 | 16841617 | 16841640 | 11 | - | 26627737 | HCT116 | viability after 15 days | CTACTTCAGTGCCGACACCCAGG | PLEKHA7 | ENSG00000166689 | -0.22846251987752075 | [657] | [346,167,453] | -2 | hSpCas9 | negative selection | 2094805 | 16851236 | 16851259 | 11 | + | 26627737 | HCT116 | viability after 15 days | AGAGATCACGTAGCTGGGCAAGG | PLEKHA7 | ENSG00000166689 | 0.7417527680508215 | [346] | [537,349,138] | 6 | hSpCas9 | negative selection | 2094806 | 16855862 | 16855885 | 11 | - | 26627737 | HCT116 | viability after 15 days | AAACCAAAGACCGTCCAGCATGG | PLEKHA7 | ENSG00000166689 | 0.7915511611539833 | [522] | [450,554,544] | 7 | hSpCas9 | negative selection | 2094807 | 16841617 | 16841640 | 11 | - | 26627737 | HCT116 | viability after 18 days | CTACTTCAGTGCCGACACCCAGG | PLEKHA7 | ENSG00000166689 | -0.12400344716090972 | [657] | [250,177,461] | -1 | hSpCas9 | negative selection | 2177120 | 16851236 | 16851259 | 11 | + | 26627737 | HCT116 | viability after 18 days | AGAGATCACGTAGCTGGGCAAGG | PLEKHA7 | ENSG00000166689 | 0.648606544562496 | [346] | [426,220,137] | 5 | hSpCas9 | negative selection | 2177121 | 16855862 | 16855885 | 11 | - | 26627737 | HCT116 | viability after 18 days | AAACCAAAGACCGTCCAGCATGG | PLEKHA7 | ENSG00000166689 | 0.5559271641216422 | [522] | [308,312,502] | 5 | hSpCas9 | negative selection | 2177122 | 16975016 | 16975039 | 11 | + | 24336569 | HL60 | viability | TTGCGTGAGCGCTATCGGCGCGG | PLEKHA7 | ENSG00000166689 | -0.05571868779234057 | [360] | [734] | 0 | hSpCas9 | negative selection | 2291415 | 16975016 | 16975039 | 11 | + | 24336569 | KBM7 | viability | TTGCGTGAGCGCTATCGGCGCGG | PLEKHA7 | ENSG00000166689 | -0.9998884799512874 | [414] | [565] | -6 | hSpCas9 | negative selection | 2358592 | 16872109 | 16872132 | 11 | + | 25494202 | A375 | resistance to PLX-4720 (puromycin) | CAGTTGTGCACTACCACGCCCGG | PLEKHA7 | ENSG00000166689 | 2.2991033152929052 | [264,100] | [164,231] | 7 | dCas9-VP64 | positive selection | 2392968 | 16857767 | 16857790 | 11 | + | 25494202 | A375 | resistance to PLX-4720 (puromycin) | GGAGCGCAGTGGCGCGATCTCAG | PLEKHA7 | ENSG00000166689 | -0.814608194487327 | [84,35] | [10,2] | -4 | dCas9-VP64 | positive selection | 2398648 | 16872109 | 16872132 | 11 | + | 25494202 | A375 | resistance to PLX-4720 (zeocin) | CAGTTGTGCACTACCACGCCCGG | PLEKHA7 | ENSG00000166689 | 0.6551513805362896 | [149,181] | [37,129] | 5 | dCas9-VP64 | positive selection | 2488223 | 16857767 | 16857790 | 11 | + | 25494202 | A375 | resistance to PLX-4720 (zeocin) | GGAGCGCAGTGGCGCGATCTCAG | PLEKHA7 | ENSG00000166689 | -1.763356426520778 | [237,164] | [17,19] | -9 | dCas9-VP64 | positive selection | 2493903 | 16826415 | 16826438 | 11 | - | 27453484 | HT29 | resistance to T3SS1-dependent cytotoxicity | AGAGCAGTACCGTTCCCAGAGGG | PLEKHA7 | ENSG00000166689 | 0.2924560339597151 | [5,5] | [6,5] | 6 | hSpCas9 | positive selection | 3011890 | 16817089 | 16817112 | 11 | + | 27453484 | HT29 | resistance to T3SS1-dependent cytotoxicity | CCACTCGTAGAGCTGCCACACGG | PLEKHA7 | ENSG00000166689 | -1.0212009076807338 | [2,2] | [0,0] | -9 | hSpCas9 | positive selection | 3011891 | 16826415 | 16826438 | 11 | - | 27453484 | HT29 | resistance to T3SS2-dependent cytotoxicity | AGAGCAGTACCGTTCCCAGAGGG | PLEKHA7 | ENSG00000166689 | 0.38965236841169715 | [5,5] | [6,4] | 6 | hSpCas9 | positive selection | 3079748 | 16817089 | 16817112 | 11 | + | 27453484 | HT29 | resistance to T3SS2-dependent cytotoxicity | CCACTCGTAGAGCTGCCACACGG | PLEKHA7 | ENSG00000166689 | -0.26681430208224755 | [2,2] | [2,0] | -4 | hSpCas9 | positive selection | 3079749 | 16826415 | 16826438 | 11 | - | 26780180 | HT29 | viability (Avana library 4 designs) | AGAGCAGTACCGTTCCCAGAGGG | PLEKHA7 | ENSG00000166689 | -0.367032232708242 | [] | [] | -6 | hSpCas9 | negative selection | 3449981 | 16817088 | 16817111 | 11 | + | 26780180 | HT29 | viability (Avana library 4 designs) | CCACTCGTAGAGCTGCCACACGG | PLEKHA7 | ENSG00000166689 | 1.37579388700047 | [] | [] | 5 | hSpCas9 | negative selection | 3449982 | 16817088 | 16817111 | 11 | + | 26780180 | A375 | viability (Avana lentiCRISPRv2) | CCACTCGTAGAGCTGCCACACGG | PLEKHA7 | ENSG00000166689 | 0.832257386015799 | [] | [] | 1 | hSpCas9 | negative selection | 3545007 | 16826415 | 16826438 | 11 | - | 26780180 | A375 | viability (Avana lentiCRISPRv2) | AGAGCAGTACCGTTCCCAGAGGG | PLEKHA7 | ENSG00000166689 | 3.28921456102128 | [] | [] | 5 | hSpCas9 | negative selection | 3545008 | 16817088 | 16817111 | 11 | + | 26780180 | A375 | viability (Avana lentiGuide) | CCACTCGTAGAGCTGCCACACGG | PLEKHA7 | ENSG00000166689 | -6.34221030338847 | [] | [] | -9 | hSpCas9 | negative selection | 3653666 | 16826415 | 16826438 | 11 | - | 26780180 | A375 | viability (Avana lentiGuide) | AGAGCAGTACCGTTCCCAGAGGG | PLEKHA7 | ENSG00000166689 | 0.85275577775518 | [] | [] | 1 | hSpCas9 | negative selection | 3653667 | 16817088 | 16817111 | 11 | + | 26780180 | A375 | resistance to vemurafenib (Avana lentiCRISPRv2) | CCACTCGTAGAGCTGCCACACGG | PLEKHA7 | ENSG00000166689 | -0.024333902332590363 | [4] | [5,2] | 0 | hSpCas9 | positive selection | 3762325 | 16826415 | 16826438 | 11 | - | 26780180 | A375 | resistance to vemurafenib (Avana lentiCRISPRv2) | AGAGCAGTACCGTTCCCAGAGGG | PLEKHA7 | ENSG00000166689 | 0.11313438112672702 | [6] | [7,6] | 3 | hSpCas9 | positive selection | 3762326 | 16817088 | 16817111 | 11 | + | 26780180 | A375 | resistance to vemurafenib (Avana lentiGuide) | CCACTCGTAGAGCTGCCACACGG | PLEKHA7 | ENSG00000166689 | -0.5655968711838351 | [4] | [2,1] | -6 | hSpCas9 | positive selection | 3870932 | 16826415 | 16826438 | 11 | - | 26780180 | A375 | resistance to vemurafenib (Avana lentiGuide) | AGAGCAGTACCGTTCCCAGAGGG | PLEKHA7 | ENSG00000166689 | 0.09339692908815056 | [7] | [6,7] | 2 | hSpCas9 | positive selection | 3870933 | 16826355 | 16826377 | 11 | - | 27760321 | OCIAML3 | viability | TCTCCGTACTCGCCAGCCGAGG | PLEKHA7 | ENSG00000166689 | 0.5237051445009215 | [1361,1129] | [1215,1627] | 6 | hSpCas9 | negative selection | 4428512 | 16826500 | 16826522 | 11 | + | 27760321 | OCIAML3 | viability | CGTATGTCCGGGTCCCACCCGG | PLEKHA7 | ENSG00000166689 | 0.1542880168491222 | [794,755] | [624,741] | 1 | hSpCas9 | negative selection | 4428513 | 16841546 | 16841568 | 11 | - | 27760321 | OCIAML3 | viability | GTCTCGATCGTCACTGAAGAGG | PLEKHA7 | ENSG00000166689 | 0.6817166906017701 | [274,250] | [301,365] | 7 | hSpCas9 | negative selection | 4428514 | 16851206 | 16851228 | 11 | + | 27760321 | OCIAML3 | viability | GCGGCTTATGCGATCCTCAGGG | PLEKHA7 | ENSG00000166689 | 0.49239628214224496 | [670,569] | [583,805] | 6 | hSpCas9 | negative selection | 4428515 | 16826355 | 16826377 | 11 | - | 27760321 | OCIAML2 | viability | TCTCCGTACTCGCCAGCCGAGG | PLEKHA7 | ENSG00000166689 | 0.5802810758928092 | [1361,1129] | [1408,1620] | 7 | hSpCas9 | negative selection | 4511975 | 16826500 | 16826522 | 11 | + | 27760321 | OCIAML2 | viability | CGTATGTCCGGGTCCCACCCGG | PLEKHA7 | ENSG00000166689 | 0.2061570441555074 | [794,755] | [636,839] | 2 | hSpCas9 | negative selection | 4511976 | 16841546 | 16841568 | 11 | - | 27760321 | OCIAML2 | viability | GTCTCGATCGTCACTGAAGAGG | PLEKHA7 | ENSG00000166689 | 0.040145327240952766 | [274,250] | [184,262] | 0 | hSpCas9 | negative selection | 4511977 | 16851206 | 16851228 | 11 | + | 27760321 | OCIAML2 | viability | GCGGCTTATGCGATCCTCAGGG | PLEKHA7 | ENSG00000166689 | 0.34824959656720633 | [670,569] | [452,878] | 5 | hSpCas9 | negative selection | 4511978 | 16826355 | 16826377 | 11 | - | 27760321 | MV411 | viability | TCTCCGTACTCGCCAGCCGAGG | PLEKHA7 | ENSG00000166689 | 1.4846865309346233 | [1361,1129] | [1872,2918] | 9 | hSpCas9 | negative selection | 4595438 | 16826500 | 16826522 | 11 | + | 27760321 | MV411 | viability | CGTATGTCCGGGTCCCACCCGG | PLEKHA7 | ENSG00000166689 | 0.2806533795331143 | [794,755] | [390,969] | 2 | hSpCas9 | negative selection | 4595439 | 16841546 | 16841568 | 11 | - | 27760321 | MV411 | viability | GTCTCGATCGTCACTGAAGAGG | PLEKHA7 | ENSG00000166689 | -0.18146827335084048 | [274,250] | [116,206] | -1 | hSpCas9 | negative selection | 4595440 | 16851206 | 16851228 | 11 | + | 27760321 | MV411 | viability | GCGGCTTATGCGATCCTCAGGG | PLEKHA7 | ENSG00000166689 | 0.4237463020415799 | [670,569] | [303,912] | 3 | hSpCas9 | negative selection | 4595441 | 16826355 | 16826377 | 11 | - | 27760321 | HL60 | viability | TCTCCGTACTCGCCAGCCGAGG | PLEKHA7 | ENSG00000166689 | 0.6364447394482844 | [1361,1129] | [1535,1616] | 7 | hSpCas9 | negative selection | 4678901 | 16826500 | 16826522 | 11 | + | 27760321 | HL60 | viability | CGTATGTCCGGGTCCCACCCGG | PLEKHA7 | ENSG00000166689 | -0.648825672525772 | [794,755] | [388,420] | -6 | hSpCas9 | negative selection | 4678902 | 16841546 | 16841568 | 11 | - | 27760321 | HL60 | viability | GTCTCGATCGTCACTGAAGAGG | PLEKHA7 | ENSG00000166689 | 0.7213994808976207 | [274,250] | [355,351] | 8 | hSpCas9 | negative selection | 4678903 | 16851206 | 16851228 | 11 | + | 27760321 | HL60 | viability | GCGGCTTATGCGATCCTCAGGG | PLEKHA7 | ENSG00000166689 | 0.261587361659681 | [670,569] | [607,602] | 3 | hSpCas9 | negative selection | 4678904 | 16826355 | 16826377 | 11 | - | 27760321 | HT1080 | viability | TCTCCGTACTCGCCAGCCGAGG | PLEKHA7 | ENSG00000166689 | 1.1536633417985644 | [1129,881] | [777,1015] | 6 | hSpCas9 | negative selection | 4762364 | 16826500 | 16826522 | 11 | + | 27760321 | HT1080 | viability | CGTATGTCCGGGTCCCACCCGG | PLEKHA7 | ENSG00000166689 | 0.242522347820324 | [755,589] | [183,462] | 1 | hSpCas9 | negative selection | 4762365 | 16841546 | 16841568 | 11 | - | 27760321 | HT1080 | viability | GTCTCGATCGTCACTGAAGAGG | PLEKHA7 | ENSG00000166689 | 0.05161975836213084 | [250,195] | [34,154] | 0 | hSpCas9 | negative selection | 4762366 | 16851206 | 16851228 | 11 | + | 27760321 | HT1080 | viability | GCGGCTTATGCGATCCTCAGGG | PLEKHA7 | ENSG00000166689 | 1.3416347975539584 | [569,444] | [467,560] | 7 | hSpCas9 | negative selection | 4762367 | 16826355 | 16826377 | 11 | - | 27760321 | HT29 | viability after 7 days | TCTCCGTACTCGCCAGCCGAGG | PLEKHA7 | ENSG00000166689 | 0.3593987969677601 | [1129,881] | [1778,1596,1617] | 5 | hSpCas9 | negative selection | 4845827 | 16826500 | 16826522 | 11 | + | 27760321 | HT29 | viability after 7 days | CGTATGTCCGGGTCCCACCCGG | PLEKHA7 | ENSG00000166689 | 0.0659949344852524 | [755,589] | [970,837,915] | 1 | hSpCas9 | negative selection | 4845828 | 16841546 | 16841568 | 11 | - | 27760321 | HT29 | viability after 7 days | GTCTCGATCGTCACTGAAGAGG | PLEKHA7 | ENSG00000166689 | -0.2220865837722411 | [250,195] | [241,245,249] | -3 | hSpCas9 | negative selection | 4845829 | 16851206 | 16851228 | 11 | + | 27760321 | HT29 | viability after 7 days | GCGGCTTATGCGATCCTCAGGG | PLEKHA7 | ENSG00000166689 | 0.14780485250581432 | [569,444] | [692,829,642] | 2 | hSpCas9 | negative selection | 4845830 | 16826355 | 16826377 | 11 | - | 27760321 | HT29 | viability after 25 days | TCTCCGTACTCGCCAGCCGAGG | PLEKHA7 | ENSG00000166689 | 0.8428726718412984 | [1129,881] | [1643,2076,2537] | 8 | hSpCas9 | negative selection | 4929290 | 16826500 | 16826522 | 11 | + | 27760321 | HT29 | viability after 25 days | CGTATGTCCGGGTCCCACCCGG | PLEKHA7 | ENSG00000166689 | 0.3909692635004456 | [755,589] | [1032,812,1195] | 4 | hSpCas9 | negative selection | 4929291 | 16841546 | 16841568 | 11 | - | 27760321 | HT29 | viability after 25 days | GTCTCGATCGTCACTGAAGAGG | PLEKHA7 | ENSG00000166689 | 0.13949292567499572 | [250,195] | [215,425,196] | 1 | hSpCas9 | negative selection | 4929292 | 16851206 | 16851228 | 11 | + | 27760321 | HT29 | viability after 25 days | GCGGCTTATGCGATCCTCAGGG | PLEKHA7 | ENSG00000166689 | 0.687408399814128 | [569,444] | [823,950,1043] | 7 | hSpCas9 | negative selection | 4929293 | 16826355 | 16826377 | 11 | - | 27760321 | HT29 | viability after 22 days | TCTCCGTACTCGCCAGCCGAGG | PLEKHA7 | ENSG00000166689 | 0.7312120428667064 | [1129,881] | [1529,1982,2292] | 8 | hSpCas9 | negative selection | 5012753 | 16826500 | 16826522 | 11 | + | 27760321 | HT29 | viability after 22 days | CGTATGTCCGGGTCCCACCCGG | PLEKHA7 | ENSG00000166689 | 0.2722369347968918 | [755,589] | [588,1218,1020] | 3 | hSpCas9 | negative selection | 5012754 | 16841546 | 16841568 | 11 | - | 27760321 | HT29 | viability after 22 days | GTCTCGATCGTCACTGAAGAGG | PLEKHA7 | ENSG00000166689 | 0.35906931865174974 | [250,195] | [522,345,117] | 4 | hSpCas9 | negative selection | 5012755 | 16851206 | 16851228 | 11 | + | 27760321 | HT29 | viability after 22 days | GCGGCTTATGCGATCCTCAGGG | PLEKHA7 | ENSG00000166689 | 0.6839432251795763 | [569,444] | [745,1138,947] | 7 | hSpCas9 | negative selection | 5012756 | 16826355 | 16826377 | 11 | - | 27760321 | HT29 | viability after 19 days | TCTCCGTACTCGCCAGCCGAGG | PLEKHA7 | ENSG00000166689 | 1.130879115133752 | [1129,881] | [2225,2261,3018] | 9 | hSpCas9 | negative selection | 5096216 | 16826500 | 16826522 | 11 | + | 27760321 | HT29 | viability after 19 days | CGTATGTCCGGGTCCCACCCGG | PLEKHA7 | ENSG00000166689 | 0.2160733048782575 | [755,589] | [893,637,1139] | 2 | hSpCas9 | negative selection | 5096217 | 16841546 | 16841568 | 11 | - | 27760321 | HT29 | viability after 19 days | GTCTCGATCGTCACTGAAGAGG | PLEKHA7 | ENSG00000166689 | -0.04916856358306709 | [250,195] | [363,376,20] | 0 | hSpCas9 | negative selection | 5096218 | 16851206 | 16851228 | 11 | + | 27760321 | HT29 | viability after 19 days | GCGGCTTATGCGATCCTCAGGG | PLEKHA7 | ENSG00000166689 | 0.8635164926619243 | [569,444] | [815,1367,961] | 8 | hSpCas9 | negative selection | 5096219 | 16826355 | 16826377 | 11 | - | 27760321 | HT29 | viability after 16 days | TCTCCGTACTCGCCAGCCGAGG | PLEKHA7 | ENSG00000166689 | 0.8479400726826745 | [1129,881] | [1754,1706,2597] | 8 | hSpCas9 | negative selection | 5179679 | 16826500 | 16826522 | 11 | + | 27760321 | HT29 | viability after 16 days | CGTATGTCCGGGTCCCACCCGG | PLEKHA7 | ENSG00000166689 | -0.008597563293850419 | [755,589] | [630,641,963] | 0 | hSpCas9 | negative selection | 5179680 | 16841546 | 16841568 | 11 | - | 27760321 | HT29 | viability after 16 days | GTCTCGATCGTCACTGAAGAGG | PLEKHA7 | ENSG00000166689 | 0.21995277685434816 | [250,195] | [388,249,244] | 2 | hSpCas9 | negative selection | 5179681 | 16851206 | 16851228 | 11 | + | 27760321 | HT29 | viability after 16 days | GCGGCTTATGCGATCCTCAGGG | PLEKHA7 | ENSG00000166689 | 0.5004186704220336 | [569,444] | [746,850,804] | 6 | hSpCas9 | negative selection | 5179682 | 16826355 | 16826377 | 11 | - | 27760321 | HT29 | viability after 13 days | TCTCCGTACTCGCCAGCCGAGG | PLEKHA7 | ENSG00000166689 | 0.6507084282638012 | [1129,881] | [1792,1999,1710] | 8 | hSpCas9 | negative selection | 5263142 | 16826500 | 16826522 | 11 | + | 27760321 | HT29 | viability after 13 days | CGTATGTCCGGGTCCCACCCGG | PLEKHA7 | ENSG00000166689 | 0.0517463585161112 | [755,589] | [814,843,770] | 0 | hSpCas9 | negative selection | 5263143 | 16841546 | 16841568 | 11 | - | 27760321 | HT29 | viability after 13 days | GTCTCGATCGTCACTGAAGAGG | PLEKHA7 | ENSG00000166689 | 0.4737905696187204 | [250,195] | [277,673,141] | 6 | hSpCas9 | negative selection | 5263144 | 16851206 | 16851228 | 11 | + | 27760321 | HT29 | viability after 13 days | GCGGCTTATGCGATCCTCAGGG | PLEKHA7 | ENSG00000166689 | 0.46778497220920134 | [569,444] | [773,1029,648] | 6 | hSpCas9 | negative selection | 5263145 | 16826355 | 16826377 | 11 | - | 27760321 | HT29 | viability after 10 days | TCTCCGTACTCGCCAGCCGAGG | PLEKHA7 | ENSG00000166689 | 0.44114012186244933 | [1129,881] | [1972,1892,1264] | 6 | hSpCas9 | negative selection | 5346605 | 16826500 | 16826522 | 11 | + | 27760321 | HT29 | viability after 10 days | CGTATGTCCGGGTCCCACCCGG | PLEKHA7 | ENSG00000166689 | -0.3609381989654761 | [755,589] | [435,796,731] | -5 | hSpCas9 | negative selection | 5346606 | 16841546 | 16841568 | 11 | - | 27760321 | HT29 | viability after 10 days | GTCTCGATCGTCACTGAAGAGG | PLEKHA7 | ENSG00000166689 | 0.529570359637924 | [250,195] | [424,504,283] | 7 | hSpCas9 | negative selection | 5346607 | 16851206 | 16851228 | 11 | + | 27760321 | HT29 | viability after 10 days | GCGGCTTATGCGATCCTCAGGG | PLEKHA7 | ENSG00000166689 | 0.5004790009196987 | [569,444] | [1293,1016,392] | 6 | hSpCas9 | negative selection | 5346608 | 16826355 | 16826377 | 11 | - | 27760321 | MOLM13 | viability | TCTCCGTACTCGCCAGCCGAGG | PLEKHA7 | ENSG00000166689 | 1.1950152445323488 | [1361,1129] | [1555,1641] | 8 | hSpCas9 | negative selection | 5430068 | 16826500 | 16826522 | 11 | + | 27760321 | MOLM13 | viability | CGTATGTCCGGGTCCCACCCGG | PLEKHA7 | ENSG00000166689 | 0.6046371724978192 | [794,755] | [993,386] | 4 | hSpCas9 | negative selection | 5430069 | 16841546 | 16841568 | 11 | - | 27760321 | MOLM13 | viability | GTCTCGATCGTCACTGAAGAGG | PLEKHA7 | ENSG00000166689 | 0.27943185728754144 | [274,250] | [273,99] | 2 | hSpCas9 | negative selection | 5430070 | 16851206 | 16851228 | 11 | + | 27760321 | MOLM13 | viability | GCGGCTTATGCGATCCTCAGGG | PLEKHA7 | ENSG00000166689 | 0.5941250797984958 | [670,569] | [678,396] | 4 | hSpCas9 | negative selection | 5430071 | 16841617 | 16841640 | 11 | - | 27869803 | HPAFII | viability after 27 days | CTACTTCAGTGCCGACACCCAGG | PLEKHA7 | ENSG00000166689 | -0.1993316581065162 | [379] | [137,203,NaN] | -1 | hSpCas9 | negative selection | 9540765 | 16851236 | 16851259 | 11 | + | 27869803 | HPAFII | viability after 27 days | AGAGATCACGTAGCTGGGCAAGG | PLEKHA7 | ENSG00000166689 | 1.0118465610866312 | [330] | [543,189,NaN] | 8 | hSpCas9 | negative selection | 9540766 | 16855862 | 16855885 | 11 | - | 27869803 | HPAFII | viability after 27 days | AAACCAAAGACCGTCCAGCATGG | PLEKHA7 | ENSG00000166689 | 0.37378436816130023 | [459] | [302,321,NaN] | 3 | hSpCas9 | negative selection | 9540767 | 16841617 | 16841640 | 11 | - | 27869803 | HPAFII | viability after 15 days | CTACTTCAGTGCCGACACCCAGG | PLEKHA7 | ENSG00000166689 | -0.0024169808847183116 | [379] | [551,317,NaN] | 0 | hSpCas9 | negative selection | 9623214 | 16851236 | 16851259 | 11 | + | 27869803 | HPAFII | viability after 15 days | AGAGATCACGTAGCTGGGCAAGG | PLEKHA7 | ENSG00000166689 | 0.9404753729055213 | [330] | [1175,375,NaN] | 9 | hSpCas9 | negative selection | 9623215 | 16855862 | 16855885 | 11 | - | 27869803 | HPAFII | viability after 15 days | AAACCAAAGACCGTCCAGCATGG | PLEKHA7 | ENSG00000166689 | 0.32154492860310246 | [459] | [676,580,NaN] | 3 | hSpCas9 | negative selection | 9623216 | 16841617 | 16841640 | 11 | - | 27869803 | ASPC1 | viability after 36 days | CTACTTCAGTGCCGACACCCAGG | PLEKHA7 | ENSG00000166689 | 0.9379422307751052 | [881] | [1120,153,556] | 8 | hSpCas9 | negative selection | 9705663 | 16851236 | 16851259 | 11 | + | 27869803 | ASPC1 | viability after 36 days | AGAGATCACGTAGCTGGGCAAGG | PLEKHA7 | ENSG00000166689 | -0.21354833851561877 | [843] | [231,258,262] | -2 | hSpCas9 | negative selection | 9705664 | 16855862 | 16855885 | 11 | - | 27869803 | ASPC1 | viability after 36 days | AAACCAAAGACCGTCCAGCATGG | PLEKHA7 | ENSG00000166689 | 0.09052398830110953 | [1518] | [1002,672,164] | 0 | hSpCas9 | negative selection | 9705665 | 16841617 | 16841640 | 11 | - | 27869803 | PATU8988S | viability after 35 days | CTACTTCAGTGCCGACACCCAGG | PLEKHA7 | ENSG00000166689 | 0.3440065368293377 | [768] | [442,342,NaN] | 4 | hSpCas9 | negative selection | 9788112 | 16851236 | 16851259 | 11 | + | 27869803 | PATU8988S | viability after 35 days | AGAGATCACGTAGCTGGGCAAGG | PLEKHA7 | ENSG00000166689 | 0.5291344441810046 | [658] | [385,379,NaN] | 6 | hSpCas9 | negative selection | 9788113 | 16855862 | 16855885 | 11 | - | 27869803 | PATU8988S | viability after 35 days | AAACCAAAGACCGTCCAGCATGG | PLEKHA7 | ENSG00000166689 | 0.4797412484849215 | [1172] | [568,748,NaN] | 5 | hSpCas9 | negative selection | 9788114 | 16841617 | 16841640 | 11 | - | 27869803 | PATU8988S | viability after 31 days | CTACTTCAGTGCCGACACCCAGG | PLEKHA7 | ENSG00000166689 | -0.07807396761606716 | [768] | [293,285,NaN] | -1 | hSpCas9 | negative selection | 9870561 | 16851236 | 16851259 | 11 | + | 27869803 | PATU8988S | viability after 31 days | AGAGATCACGTAGCTGGGCAAGG | PLEKHA7 | ENSG00000166689 | 0.6169198581825793 | [658] | [336,486,NaN] | 7 | hSpCas9 | negative selection | 9870562 | 16855862 | 16855885 | 11 | - | 27869803 | PATU8988S | viability after 31 days | AAACCAAAGACCGTCCAGCATGG | PLEKHA7 | ENSG00000166689 | 0.45811145669599407 | [1172] | [521,795,NaN] | 5 | hSpCas9 | negative selection | 9870563 | 16841617 | 16841640 | 11 | - | 27869803 | HPAFII | viability after 35 days | CTACTTCAGTGCCGACACCCAGG | PLEKHA7 | ENSG00000166689 | 0.6111874680222777 | [379] | [116,492,NaN] | 4 | hSpCas9 | negative selection | 9953010 | 16851236 | 16851259 | 11 | + | 27869803 | HPAFII | viability after 35 days | AGAGATCACGTAGCTGGGCAAGG | PLEKHA7 | ENSG00000166689 | 1.208150714569563 | [330] | [571,178,NaN] | 7 | hSpCas9 | negative selection | 9953011 | 16855862 | 16855885 | 11 | - | 27869803 | HPAFII | viability after 35 days | AAACCAAAGACCGTCCAGCATGG | PLEKHA7 | ENSG00000166689 | 0.5076993132081324 | [459] | [284,382,NaN] | 3 | hSpCas9 | negative selection | 9953012 | 16841617 | 16841640 | 11 | - | 27869803 | HPAFII | viability after 31 days | CTACTTCAGTGCCGACACCCAGG | PLEKHA7 | ENSG00000166689 | -0.2960897922734367 | [379] | [110,241,NaN] | -2 | hSpCas9 | negative selection | 10035459 | 16851236 | 16851259 | 11 | + | 27869803 | HPAFII | viability after 31 days | AGAGATCACGTAGCTGGGCAAGG | PLEKHA7 | ENSG00000166689 | 0.8019930018212116 | [330] | [443,192,NaN] | 6 | hSpCas9 | negative selection | 10035460 | 16855862 | 16855885 | 11 | - | 27869803 | HPAFII | viability after 31 days | AAACCAAAGACCGTCCAGCATGG | PLEKHA7 | ENSG00000166689 | 0.4650322628725263 | [459] | [352,359,NaN] | 3 | hSpCas9 | negative selection | 10035461 | 16817168 | 16817191 | 11 | - | 28162770 | P31FUJ | viability | AAGTGACTACAAGTATGCGCAGG | PLEKHA7 | ENSG00000166689 | 0.2977125122844011 | [80] | [116] | 3 | hSpCas9 | negative selection | 10212703 | 16826231 | 16826254 | 11 | - | 28162770 | P31FUJ | viability | GGAGAACAGAATGGGACTGGTGG | PLEKHA7 | ENSG00000166689 | -0.7380375126648009 | [87] | [61] | -5 | hSpCas9 | negative selection | 10212704 | 16816836 | 16816859 | 11 | - | 28162770 | P31FUJ | viability | GGAGTGTGGACATCTCGCTGGGG | PLEKHA7 | ENSG00000166689 | 0.7083041065320527 | [224] | [431] | 7 | hSpCas9 | negative selection | 10212705 | 16854948 | 16854971 | 11 | + | 28162770 | P31FUJ | viability | GGTCTCTCTTCCCAAAGCTGTGG | PLEKHA7 | ENSG00000166689 | -0.33704217209135545 | [372] | [346] | -3 | hSpCas9 | negative selection | 10212706 | 16854934 | 16854957 | 11 | - | 28162770 | P31FUJ | viability | AGAGAGACCAGGCCATTCGGAGG | PLEKHA7 | ENSG00000166689 | -0.2232161555851806 | [149] | [150] | -2 | hSpCas9 | negative selection | 10212707 | 16826416 | 16826439 | 11 | - | 28162770 | P31FUJ | viability | GAGAGCAGTACCGTTCCCAGAGG | PLEKHA7 | ENSG00000166689 | -0.41306915007815015 | [314] | [277] | -4 | hSpCas9 | negative selection | 10212708 | 16826157 | 16826180 | 11 | - | 28162770 | P31FUJ | viability | GAAGAGCAATCTGGCCCAGGTGG | PLEKHA7 | ENSG00000166689 | -0.060849521625083725 | [78] | [88] | 0 | hSpCas9 | negative selection | 10212709 | 16817168 | 16817191 | 11 | - | 28162770 | TF1 | viability | AAGTGACTACAAGTATGCGCAGG | PLEKHA7 | ENSG00000166689 | NaN | [NaN] | [105] | 1 | hSpCas9 | negative selection | 10382069 | 16826231 | 16826254 | 11 | - | 28162770 | TF1 | viability | GGAGAACAGAATGGGACTGGTGG | PLEKHA7 | ENSG00000166689 | NaN | [NaN] | [38] | 1 | hSpCas9 | negative selection | 10382070 | 16816836 | 16816859 | 11 | - | 28162770 | TF1 | viability | GGAGTGTGGACATCTCGCTGGGG | PLEKHA7 | ENSG00000166689 | NaN | [NaN] | [112] | 1 | hSpCas9 | negative selection | 10382071 | 16854948 | 16854971 | 11 | + | 28162770 | TF1 | viability | GGTCTCTCTTCCCAAAGCTGTGG | PLEKHA7 | ENSG00000166689 | NaN | [NaN] | [265] | 1 | hSpCas9 | negative selection | 10382072 | 16854934 | 16854957 | 11 | - | 28162770 | TF1 | viability | AGAGAGACCAGGCCATTCGGAGG | PLEKHA7 | ENSG00000166689 | NaN | [NaN] | [117] | 1 | hSpCas9 | negative selection | 10382073 | 16826416 | 16826439 | 11 | - | 28162770 | TF1 | viability | GAGAGCAGTACCGTTCCCAGAGG | PLEKHA7 | ENSG00000166689 | NaN | [NaN] | [211] | 1 | hSpCas9 | negative selection | 10382074 | 16826157 | 16826180 | 11 | - | 28162770 | TF1 | viability | GAAGAGCAATCTGGCCCAGGTGG | PLEKHA7 | ENSG00000166689 | NaN | [NaN] | [125] | 1 | hSpCas9 | negative selection | 10382075 | 16817168 | 16817191 | 11 | - | 28162770 | SKM1 | viability | AAGTGACTACAAGTATGCGCAGG | PLEKHA7 | ENSG00000166689 | -0.38142910663602425 | [27] | [37] | -3 | hSpCas9 | negative selection | 10551435 | 16826231 | 16826254 | 11 | - | 28162770 | SKM1 | viability | GGAGAACAGAATGGGACTGGTGG | PLEKHA7 | ENSG00000166689 | -0.2984397419649927 | [31] | [45] | -3 | hSpCas9 | negative selection | 10551436 | 16816836 | 16816859 | 11 | - | 28162770 | SKM1 | viability | GGAGTGTGGACATCTCGCTGGGG | PLEKHA7 | ENSG00000166689 | 1.2298372334976126 | [81] | [339] | 9 | hSpCas9 | negative selection | 10551437 | 16854948 | 16854971 | 11 | + | 28162770 | SKM1 | viability | GGTCTCTCTTCCCAAAGCTGTGG | PLEKHA7 | ENSG00000166689 | -0.5676845092893207 | [82] | [98] | -4 | hSpCas9 | negative selection | 10551438 | 16854934 | 16854957 | 11 | - | 28162770 | SKM1 | viability | AGAGAGACCAGGCCATTCGGAGG | PLEKHA7 | ENSG00000166689 | -0.42968427524324515 | [47] | [62] | -4 | hSpCas9 | negative selection | 10551439 | 16826416 | 16826439 | 11 | - | 28162770 | SKM1 | viability | GAGAGCAGTACCGTTCCCAGAGG | PLEKHA7 | ENSG00000166689 | 0.2300868131264488 | [67] | [140] | 2 | hSpCas9 | negative selection | 10551440 | 16826157 | 16826180 | 11 | - | 28162770 | SKM1 | viability | GAAGAGCAATCTGGCCCAGGTGG | PLEKHA7 | ENSG00000166689 | 0.05246741989413528 | [17] | [32] | 0 | hSpCas9 | negative selection | 10551441 | 16817168 | 16817191 | 11 | - | 28162770 | SKM1 | viability | AAGTGACTACAAGTATGCGCAGG | PLEKHA7 | ENSG00000166689 | -0.38142910663602425 | [27] | [37] | -3 | hSpCas9 | negative selection | 10720801 | 16826231 | 16826254 | 11 | - | 28162770 | SKM1 | viability | GGAGAACAGAATGGGACTGGTGG | PLEKHA7 | ENSG00000166689 | -0.2984397419649927 | [31] | [45] | -3 | hSpCas9 | negative selection | 10720802 | 16816836 | 16816859 | 11 | - | 28162770 | SKM1 | viability | GGAGTGTGGACATCTCGCTGGGG | PLEKHA7 | ENSG00000166689 | 1.2298372334976126 | [81] | [339] | 9 | hSpCas9 | negative selection | 10720803 | 16854948 | 16854971 | 11 | + | 28162770 | SKM1 | viability | GGTCTCTCTTCCCAAAGCTGTGG | PLEKHA7 | ENSG00000166689 | -0.5676845092893207 | [82] | [98] | -4 | hSpCas9 | negative selection | 10720804 | 16854934 | 16854957 | 11 | - | 28162770 | SKM1 | viability | AGAGAGACCAGGCCATTCGGAGG | PLEKHA7 | ENSG00000166689 | -0.42968427524324515 | [47] | [62] | -4 | hSpCas9 | negative selection | 10720805 | 16826416 | 16826439 | 11 | - | 28162770 | SKM1 | viability | GAGAGCAGTACCGTTCCCAGAGG | PLEKHA7 | ENSG00000166689 | 0.2300868131264488 | [67] | [140] | 2 | hSpCas9 | negative selection | 10720806 | 16826157 | 16826180 | 11 | - | 28162770 | SKM1 | viability | GAAGAGCAATCTGGCCCAGGTGG | PLEKHA7 | ENSG00000166689 | 0.05246741989413528 | [17] | [32] | 0 | hSpCas9 | negative selection | 10720807 | 16817168 | 16817191 | 11 | - | 28162770 | PL21 | viability | AAGTGACTACAAGTATGCGCAGG | PLEKHA7 | ENSG00000166689 | 0.30705481840583193 | [103] | [55] | 2 | hSpCas9 | negative selection | 10890167 | 16826231 | 16826254 | 11 | - | 28162770 | PL21 | viability | GGAGAACAGAATGGGACTGGTGG | PLEKHA7 | ENSG00000166689 | 1.3143106344086315 | [84] | [91] | 9 | hSpCas9 | negative selection | 10890168 | 16816836 | 16816859 | 11 | - | 28162770 | PL21 | viability | GGAGTGTGGACATCTCGCTGGGG | PLEKHA7 | ENSG00000166689 | 0.5748844078201307 | [235] | [152] | 5 | hSpCas9 | negative selection | 10890169 | 16854948 | 16854971 | 11 | + | 28162770 | PL21 | viability | GGTCTCTCTTCCCAAAGCTGTGG | PLEKHA7 | ENSG00000166689 | -1.0491194126998098 | [270] | [56] | -6 | hSpCas9 | negative selection | 10890170 | 16854934 | 16854957 | 11 | - | 28162770 | PL21 | viability | AGAGAGACCAGGCCATTCGGAGG | PLEKHA7 | ENSG00000166689 | 0.960951950609894 | [143] | [121] | 7 | hSpCas9 | negative selection | 10890171 | 16826416 | 16826439 | 11 | - | 28162770 | PL21 | viability | GAGAGCAGTACCGTTCCCAGAGG | PLEKHA7 | ENSG00000166689 | 0.2712227125508026 | [197] | [103] | 2 | hSpCas9 | negative selection | 10890172 | 16826157 | 16826180 | 11 | - | 28162770 | PL21 | viability | GAAGAGCAATCTGGCCCAGGTGG | PLEKHA7 | ENSG00000166689 | 1.129750286597922 | [83] | [79] | 8 | hSpCas9 | negative selection | 10890173 | 16817168 | 16817191 | 11 | - | 28162770 | P31FUJ | viability | AAGTGACTACAAGTATGCGCAGG | PLEKHA7 | ENSG00000166689 | 0.2977125122844011 | [80] | [116] | 3 | hSpCas9 | negative selection | 11059533 | 16826231 | 16826254 | 11 | - | 28162770 | P31FUJ | viability | GGAGAACAGAATGGGACTGGTGG | PLEKHA7 | ENSG00000166689 | -0.7380375126648009 | [87] | [61] | -5 | hSpCas9 | negative selection | 11059534 | 16816836 | 16816859 | 11 | - | 28162770 | P31FUJ | viability | GGAGTGTGGACATCTCGCTGGGG | PLEKHA7 | ENSG00000166689 | 0.7083041065320527 | [224] | [431] | 7 | hSpCas9 | negative selection | 11059535 | 16854948 | 16854971 | 11 | + | 28162770 | P31FUJ | viability | GGTCTCTCTTCCCAAAGCTGTGG | PLEKHA7 | ENSG00000166689 | -0.33704217209135545 | [372] | [346] | -3 | hSpCas9 | negative selection | 11059536 | 16854934 | 16854957 | 11 | - | 28162770 | P31FUJ | viability | AGAGAGACCAGGCCATTCGGAGG | PLEKHA7 | ENSG00000166689 | -0.2232161555851806 | [149] | [150] | -2 | hSpCas9 | negative selection | 11059537 | 16826416 | 16826439 | 11 | - | 28162770 | P31FUJ | viability | GAGAGCAGTACCGTTCCCAGAGG | PLEKHA7 | ENSG00000166689 | -0.41306915007815015 | [314] | [277] | -4 | hSpCas9 | negative selection | 11059538 | 16826157 | 16826180 | 11 | - | 28162770 | P31FUJ | viability | GAAGAGCAATCTGGCCCAGGTGG | PLEKHA7 | ENSG00000166689 | -0.060849521625083725 | [78] | [88] | 0 | hSpCas9 | negative selection | 11059539 | 16817168 | 16817191 | 11 | - | 28162770 | OCIAML5 | viability | AAGTGACTACAAGTATGCGCAGG | PLEKHA7 | ENSG00000166689 | -0.4468100923777387 | [73] | [97] | -3 | hSpCas9 | negative selection | 11228899 | 16826231 | 16826254 | 11 | - | 28162770 | OCIAML5 | viability | GGAGAACAGAATGGGACTGGTGG | PLEKHA7 | ENSG00000166689 | -1.0180765223029262 | [45] | [40] | -6 | hSpCas9 | negative selection | 11228900 | 16816836 | 16816859 | 11 | - | 28162770 | OCIAML5 | viability | GGAGTGTGGACATCTCGCTGGGG | PLEKHA7 | ENSG00000166689 | 0.6177367318457386 | [125] | [348] | 5 | hSpCas9 | negative selection | 11228901 | 16854948 | 16854971 | 11 | + | 28162770 | OCIAML5 | viability | GGTCTCTCTTCCCAAAGCTGTGG | PLEKHA7 | ENSG00000166689 | 0.021587695270589735 | [160] | [294] | 0 | hSpCas9 | negative selection | 11228902 | 16854934 | 16854957 | 11 | - | 28162770 | OCIAML5 | viability | AGAGAGACCAGGCCATTCGGAGG | PLEKHA7 | ENSG00000166689 | 0.16273043106408344 | [96] | [195] | 1 | hSpCas9 | negative selection | 11228903 | 16826416 | 16826439 | 11 | - | 28162770 | OCIAML5 | viability | GAGAGCAGTACCGTTCCCAGAGG | PLEKHA7 | ENSG00000166689 | 0.3271022748219352 | [120] | [273] | 2 | hSpCas9 | negative selection | 11228904 | 16826157 | 16826180 | 11 | - | 28162770 | OCIAML5 | viability | GAAGAGCAATCTGGCCCAGGTGG | PLEKHA7 | ENSG00000166689 | 0.5660768392826683 | [57] | [154] | 5 | hSpCas9 | negative selection | 11228905 | 16817168 | 16817191 | 11 | - | 28162770 | EOL1 | viability | AAGTGACTACAAGTATGCGCAGG | PLEKHA7 | ENSG00000166689 | 0.42204743104135134 | [101] | [71] | 4 | hSpCas9 | negative selection | 11398265 | 16826231 | 16826254 | 11 | - | 28162770 | EOL1 | viability | GGAGAACAGAATGGGACTGGTGG | PLEKHA7 | ENSG00000166689 | 0.6749338814990623 | [106] | [89] | 6 | hSpCas9 | negative selection | 11398266 | 16816836 | 16816859 | 11 | - | 28162770 | EOL1 | viability | GGAGTGTGGACATCTCGCTGGGG | PLEKHA7 | ENSG00000166689 | 0.03364920872991717 | [470] | [253] | 0 | hSpCas9 | negative selection | 11398267 | 16854948 | 16854971 | 11 | + | 28162770 | EOL1 | viability | GGTCTCTCTTCCCAAAGCTGTGG | PLEKHA7 | ENSG00000166689 | 0.05255538394660614 | [387] | [211] | 0 | hSpCas9 | negative selection | 11398268 | 16854934 | 16854957 | 11 | - | 28162770 | EOL1 | viability | AGAGAGACCAGGCCATTCGGAGG | PLEKHA7 | ENSG00000166689 | -0.21941800280909707 | [178] | [80] | -2 | hSpCas9 | negative selection | 11398269 | 16826416 | 16826439 | 11 | - | 28162770 | EOL1 | viability | GAGAGCAGTACCGTTCCCAGAGG | PLEKHA7 | ENSG00000166689 | 0.7277470641368275 | [297] | [259] | 6 | hSpCas9 | negative selection | 11398270 | 16826157 | 16826180 | 11 | - | 28162770 | EOL1 | viability | GAAGAGCAATCTGGCCCAGGTGG | PLEKHA7 | ENSG00000166689 | -1.3200745971493788 | [108] | [22] | -7 | hSpCas9 | negative selection | 11398271 | 16817168 | 16817191 | 11 | - | 28162770 | MOLM13 | viability | AAGTGACTACAAGTATGCGCAGG | PLEKHA7 | ENSG00000166689 | -0.48678662794593075 | [187] | [96] | -3 | hSpCas9 | negative selection | 11567631 | 16826231 | 16826254 | 11 | - | 28162770 | MOLM13 | viability | GGAGAACAGAATGGGACTGGTGG | PLEKHA7 | ENSG00000166689 | 0.9060104939364642 | [92] | [125] | 7 | hSpCas9 | negative selection | 11567632 | 16816836 | 16816859 | 11 | - | 28162770 | MOLM13 | viability | GGAGTGTGGACATCTCGCTGGGG | PLEKHA7 | ENSG00000166689 | 1.11669259748929 | [360] | [565] | 8 | hSpCas9 | negative selection | 11567633 | 16854948 | 16854971 | 11 | + | 28162770 | MOLM13 | viability | GGTCTCTCTTCCCAAAGCTGTGG | PLEKHA7 | ENSG00000166689 | -0.7870088092105356 | [388] | [162] | -4 | hSpCas9 | negative selection | 11567634 | 16854934 | 16854957 | 11 | - | 28162770 | MOLM13 | viability | AGAGAGACCAGGCCATTCGGAGG | PLEKHA7 | ENSG00000166689 | -0.26664947522708743 | [197] | [118] | -2 | hSpCas9 | negative selection | 11567635 | 16826416 | 16826439 | 11 | - | 28162770 | MOLM13 | viability | GAGAGCAGTACCGTTCCCAGAGG | PLEKHA7 | ENSG00000166689 | -0.26469777211105305 | [328] | [197] | -2 | hSpCas9 | negative selection | 11567636 | 16826157 | 16826180 | 11 | - | 28162770 | MOLM13 | viability | GAAGAGCAATCTGGCCCAGGTGG | PLEKHA7 | ENSG00000166689 | -0.5865584024777979 | [107] | [51] | -3 | hSpCas9 | negative selection | 11567637 | 16817168 | 16817191 | 11 | - | 28162770 | HEL | viability | AAGTGACTACAAGTATGCGCAGG | PLEKHA7 | ENSG00000166689 | -0.2901469721411061 | [146] | [76] | -2 | hSpCas9 | negative selection | 11736997 | 16826231 | 16826254 | 11 | - | 28162770 | HEL | viability | GGAGAACAGAATGGGACTGGTGG | PLEKHA7 | ENSG00000166689 | -0.34384065223732163 | [106] | [53] | -2 | hSpCas9 | negative selection | 11736998 | 16816836 | 16816859 | 11 | - | 28162770 | HEL | viability | GGAGTGTGGACATCTCGCTGGGG | PLEKHA7 | ENSG00000166689 | 0.6985266101861037 | [278] | [289] | 6 | hSpCas9 | negative selection | 11736999 | 16854948 | 16854971 | 11 | + | 28162770 | HEL | viability | GGTCTCTCTTCCCAAAGCTGTGG | PLEKHA7 | ENSG00000166689 | 0.39630093669725797 | [362] | [305] | 3 | hSpCas9 | negative selection | 11737000 | 16854934 | 16854957 | 11 | - | 28162770 | HEL | viability | AGAGAGACCAGGCCATTCGGAGG | PLEKHA7 | ENSG00000166689 | -0.36411483904070563 | [210] | [104] | -3 | hSpCas9 | negative selection | 11737001 | 16826416 | 16826439 | 11 | - | 28162770 | HEL | viability | GAGAGCAGTACCGTTCCCAGAGG | PLEKHA7 | ENSG00000166689 | 0.2108930450349592 | [258] | [191] | 1 | hSpCas9 | negative selection | 11737002 | 16826157 | 16826180 | 11 | - | 28162770 | HEL | viability | GAAGAGCAATCTGGCCCAGGTGG | PLEKHA7 | ENSG00000166689 | 0.6792647080254709 | [77] | [79] | 6 | hSpCas9 | negative selection | 11737003 | 16817168 | 16817191 | 11 | - | 28162770 | MV411 | viability | AAGTGACTACAAGTATGCGCAGG | PLEKHA7 | ENSG00000166689 | 1.3088380954469188 | [68] | [143] | 9 | hSpCas9 | negative selection | 11906363 | 16826231 | 16826254 | 11 | - | 28162770 | MV411 | viability | GGAGAACAGAATGGGACTGGTGG | PLEKHA7 | ENSG00000166689 | 1.159974709532436 | [67] | [127] | 8 | hSpCas9 | negative selection | 11906364 | 16816836 | 16816859 | 11 | - | 28162770 | MV411 | viability | GGAGTGTGGACATCTCGCTGGGG | PLEKHA7 | ENSG00000166689 | -1.0028858033014645 | [225] | [94] | -6 | hSpCas9 | negative selection | 11906365 | 16854948 | 16854971 | 11 | + | 28162770 | MV411 | viability | GGTCTCTCTTCCCAAAGCTGTGG | PLEKHA7 | ENSG00000166689 | 0.0749703547780097 | [212] | [188] | 0 | hSpCas9 | negative selection | 11906366 | 16854934 | 16854957 | 11 | - | 28162770 | MV411 | viability | AGAGAGACCAGGCCATTCGGAGG | PLEKHA7 | ENSG00000166689 | 0.3073090067601741 | [117] | [122] | 2 | hSpCas9 | negative selection | 11906367 | 16826416 | 16826439 | 11 | - | 28162770 | MV411 | viability | GAGAGCAGTACCGTTCCCAGAGG | PLEKHA7 | ENSG00000166689 | 0.20544346211814823 | [243] | [236] | 1 | hSpCas9 | negative selection | 11906368 | 16826157 | 16826180 | 11 | - | 28162770 | MV411 | viability | GAAGAGCAATCTGGCCCAGGTGG | PLEKHA7 | ENSG00000166689 | 0.7958741754788177 | [79] | [116] | 7 | hSpCas9 | negative selection | 11906369 | 16817168 | 16817191 | 11 | - | 28162770 | MONOMAC1 | viability | AAGTGACTACAAGTATGCGCAGG | PLEKHA7 | ENSG00000166689 | -1.1481272465786072 | [57] | [29] | -7 | hSpCas9 | negative selection | 12075729 | 16826231 | 16826254 | 11 | - | 28162770 | MONOMAC1 | viability | GGAGAACAGAATGGGACTGGTGG | PLEKHA7 | ENSG00000166689 | 0.7551346278498313 | [45] | [88] | 7 | hSpCas9 | negative selection | 12075730 | 16816836 | 16816859 | 11 | - | 28162770 | MONOMAC1 | viability | GGAGTGTGGACATCTCGCTGGGG | PLEKHA7 | ENSG00000166689 | -0.24115940029186148 | [165] | [160] | -2 | hSpCas9 | negative selection | 12075731 | 16854948 | 16854971 | 11 | + | 28162770 | MONOMAC1 | viability | GGTCTCTCTTCCCAAAGCTGTGG | PLEKHA7 | ENSG00000166689 | -0.028060675010790292 | [168] | [189] | 0 | hSpCas9 | negative selection | 12075732 | 16854934 | 16854957 | 11 | - | 28162770 | MONOMAC1 | viability | AGAGAGACCAGGCCATTCGGAGG | PLEKHA7 | ENSG00000166689 | -0.7395640814603129 | [133] | [91] | -6 | hSpCas9 | negative selection | 12075733 | 16826416 | 16826439 | 11 | - | 28162770 | MONOMAC1 | viability | GAGAGCAGTACCGTTCCCAGAGG | PLEKHA7 | ENSG00000166689 | 0.21534619877331218 | [135] | [180] | 2 | hSpCas9 | negative selection | 12075734 | 16826157 | 16826180 | 11 | - | 28162770 | MONOMAC1 | viability | GAAGAGCAATCTGGCCCAGGTGG | PLEKHA7 | ENSG00000166689 | 1.7402273975924838 | [46] | [179] | 9 | hSpCas9 | negative selection | 12075735 | 16817168 | 16817191 | 11 | - | 28162770 | OCIAML2 | viability | AAGTGACTACAAGTATGCGCAGG | PLEKHA7 | ENSG00000166689 | 1.428223451300939 | [11] | [178] | 9 | hSpCas9 | negative selection | 12245095 | 16826231 | 16826254 | 11 | - | 28162770 | OCIAML2 | viability | GGAGAACAGAATGGGACTGGTGG | PLEKHA7 | ENSG00000166689 | 0.8289304566167465 | [12] | [127] | 7 | hSpCas9 | negative selection | 12245096 | 16816836 | 16816859 | 11 | - | 28162770 | OCIAML2 | viability | GGAGTGTGGACATCTCGCTGGGG | PLEKHA7 | ENSG00000166689 | -0.24584288876533048 | [42] | [200] | -2 | hSpCas9 | negative selection | 12245097 | 16854948 | 16854971 | 11 | + | 28162770 | OCIAML2 | viability | GGTCTCTCTTCCCAAAGCTGTGG | PLEKHA7 | ENSG00000166689 | -0.25339910902149204 | [39] | [185] | -2 | hSpCas9 | negative selection | 12245098 | 16854934 | 16854957 | 11 | - | 28162770 | OCIAML2 | viability | AGAGAGACCAGGCCATTCGGAGG | PLEKHA7 | ENSG00000166689 | 1.8212857005787613 | [16] | [332] | 9 | hSpCas9 | negative selection | 12245099 | 16826416 | 16826439 | 11 | - | 28162770 | OCIAML2 | viability | GAGAGCAGTACCGTTCCCAGAGG | PLEKHA7 | ENSG00000166689 | 0.5591175181518908 | [41] | [342] | 5 | hSpCas9 | negative selection | 12245100 | 16826157 | 16826180 | 11 | - | 28162770 | OCIAML2 | viability | GAAGAGCAATCTGGCCCAGGTGG | PLEKHA7 | ENSG00000166689 | 0.07685797006033201 | [12] | [75] | 0 | hSpCas9 | negative selection | 12245101 | 16817168 | 16817191 | 11 | - | 28162770 | OCIAML3 | viability | AAGTGACTACAAGTATGCGCAGG | PLEKHA7 | ENSG00000166689 | -0.8025942621355806 | [25] | [44] | -5 | hSpCas9 | negative selection | 12414461 | 16826231 | 16826254 | 11 | - | 28162770 | OCIAML3 | viability | GGAGAACAGAATGGGACTGGTGG | PLEKHA7 | ENSG00000166689 | 0.36751821186120126 | [18] | [73] | 3 | hSpCas9 | negative selection | 12414462 | 16816836 | 16816859 | 11 | - | 28162770 | OCIAML3 | viability | GGAGTGTGGACATCTCGCTGGGG | PLEKHA7 | ENSG00000166689 | -0.0941617532409576 | [63] | [180] | 0 | hSpCas9 | negative selection | 12414463 | 16854948 | 16854971 | 11 | + | 28162770 | OCIAML3 | viability | GGTCTCTCTTCCCAAAGCTGTGG | PLEKHA7 | ENSG00000166689 | 0.019809723069178165 | [65] | [201] | 0 | hSpCas9 | negative selection | 12414464 | 16854934 | 16854957 | 11 | - | 28162770 | OCIAML3 | viability | AGAGAGACCAGGCCATTCGGAGG | PLEKHA7 | ENSG00000166689 | 0.433473096097944 | [38] | [158] | 4 | hSpCas9 | negative selection | 12414465 | 16826416 | 16826439 | 11 | - | 28162770 | OCIAML3 | viability | GAGAGCAGTACCGTTCCCAGAGG | PLEKHA7 | ENSG00000166689 | -0.43225657032755105 | [58] | [131] | -3 | hSpCas9 | negative selection | 12414466 | 16826157 | 16826180 | 11 | - | 28162770 | OCIAML3 | viability | GAAGAGCAATCTGGCCCAGGTGG | PLEKHA7 | ENSG00000166689 | -0.20169021754540273 | [15] | [41] | -1 | hSpCas9 | negative selection | 12414467 |