Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:130271
• Symbol:PLEKHH2
• Description:pleckstrin homology, MyTH4 and FERM domain containing H2

DataSource: http://genomecrispr.dkfz.de/#!/results/PLEKHH2

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
43700585	43700608	2	-	26472758	Jiyoye	viability	CAAGAAGGAAAACGGTGCAGGGG	PLEKHH2	ENSG00000152527	0.6565348504425907	[158]	[188]	5	hSpCas9	negative selection	122236
43710283	43710306	2	+	26472758	Jiyoye	viability	CGGTGGTTTGTTCTTAAAGGTGG	PLEKHH2	ENSG00000152527	0.1492388433117583	[225]	[188]	1	hSpCas9	negative selection	122237
43710263	43710286	2	+	26472758	Jiyoye	viability	AAGTCAAGTCTTGGAAGCGGCGG	PLEKHH2	ENSG00000152527	0.0002657631104299174	[235]	[177]	0	hSpCas9	negative selection	122238
43729670	43729693	2	+	26472758	Jiyoye	viability	GGAAGCAACAATGTAAACGTTGG	PLEKHH2	ENSG00000152527	0.5615035278971672	[61]	[68]	4	hSpCas9	negative selection	122239
43743909	43743932	2	-	26472758	Jiyoye	viability	AACGCAAATCCAGACTGCGCTGG	PLEKHH2	ENSG00000152527	-2.697161278308862	[42]	[4]	-9	hSpCas9	negative selection	122240
43758936	43758959	2	-	26472758	Jiyoye	viability	CAGCAGCACTGTGTCCCCGGAGG	PLEKHH2	ENSG00000152527	1.1362140599004507	[218]	[362]	7	hSpCas9	negative selection	122241
43692642	43692665	2	+	26472758	Jiyoye	viability	GGAATTGCAACTTGAAGAGCAGG	PLEKHH2	ENSG00000152527	2.3052957674866597	[21]	[81]	9	hSpCas9	negative selection	122242
43699823	43699846	2	+	26472758	Jiyoye	viability	GATGAGGAAGACGGGAGCAAAGG	PLEKHH2	ENSG00000152527	0.30504259646891985	[277]	[258]	2	hSpCas9	negative selection	122243
43700339	43700362	2	-	26472758	Jiyoye	viability	ATCCTGTCAGAGCTTAACTGTGG	PLEKHH2	ENSG00000152527	-0.21131674278047718	[369]	[240]	-1	hSpCas9	negative selection	122244
43706388	43706411	2	-	26472758	Jiyoye	viability	CAAAGTTGTATACACTGGGGTGG	PLEKHH2	ENSG00000152527	2.0952313751911333	[17]	[57]	9	hSpCas9	negative selection	122245
43700585	43700608	2	-	26472758	KBM7	viability	CAAGAAGGAAAACGGTGCAGGGG	PLEKHH2	ENSG00000152527	-0.07825942942352127	[666,353]	[299,150]	-1	hSpCas9	negative selection	313354
43710283	43710306	2	+	26472758	KBM7	viability	CGGTGGTTTGTTCTTAAAGGTGG	PLEKHH2	ENSG00000152527	-0.23638823128274528	[623,538]	[193,264]	-2	hSpCas9	negative selection	313355
43710263	43710286	2	+	26472758	KBM7	viability	AAGTCAAGTCTTGGAAGCGGCGG	PLEKHH2	ENSG00000152527	0.187696473726249	[612,456]	[252,310]	2	hSpCas9	negative selection	313356
43729670	43729693	2	+	26472758	KBM7	viability	GGAAGCAACAATGTAAACGTTGG	PLEKHH2	ENSG00000152527	0.2537510607799451	[501,494]	[334,231]	2	hSpCas9	negative selection	313357
43743909	43743932	2	-	26472758	KBM7	viability	AACGCAAATCCAGACTGCGCTGG	PLEKHH2	ENSG00000152527	-0.4362867235388044	[71,59]	[25,19]	-4	hSpCas9	negative selection	313358
43758936	43758959	2	-	26472758	KBM7	viability	CAGCAGCACTGTGTCCCCGGAGG	PLEKHH2	ENSG00000152527	0.23853912019245505	[1155,751]	[400,626]	2	hSpCas9	negative selection	313359
43692642	43692665	2	+	26472758	KBM7	viability	GGAATTGCAACTTGAAGAGCAGG	PLEKHH2	ENSG00000152527	-0.05233207397493245	[282,371]	[126,172]	0	hSpCas9	negative selection	313360
43699823	43699846	2	+	26472758	KBM7	viability	GATGAGGAAGACGGGAGCAAAGG	PLEKHH2	ENSG00000152527	-0.2741565778133075	[987,931]	[402,347]	-3	hSpCas9	negative selection	313361
43700339	43700362	2	-	26472758	KBM7	viability	ATCCTGTCAGAGCTTAACTGTGG	PLEKHH2	ENSG00000152527	-0.022392534814270615	[1462,1406]	[642,686]	0	hSpCas9	negative selection	313362
43706388	43706411	2	-	26472758	KBM7	viability	CAAAGTTGTATACACTGGGGTGG	PLEKHH2	ENSG00000152527	0.25511746987640804	[168,148]	[96,81]	2	hSpCas9	negative selection	313363
43700585	43700608	2	-	26472758	Raji	viability	CAAGAAGGAAAACGGTGCAGGGG	PLEKHH2	ENSG00000152527	0.43302194959933665	[232]	[72]	4	hSpCas9	negative selection	504472
43710283	43710306	2	+	26472758	Raji	viability	CGGTGGTTTGTTCTTAAAGGTGG	PLEKHH2	ENSG00000152527	-0.20381815292070438	[401]	[80]	-2	hSpCas9	negative selection	504473
43710263	43710286	2	+	26472758	Raji	viability	AAGTCAAGTCTTGGAAGCGGCGG	PLEKHH2	ENSG00000152527	-0.945357926698374	[389]	[46]	-6	hSpCas9	negative selection	504474
43729670	43729693	2	+	26472758	Raji	viability	GGAAGCAACAATGTAAACGTTGG	PLEKHH2	ENSG00000152527	0.31220332726209765	[176]	[50]	3	hSpCas9	negative selection	504475
43743909	43743932	2	-	26472758	Raji	viability	AACGCAAATCCAGACTGCGCTGG	PLEKHH2	ENSG00000152527	-0.3076539639052447	[15]	[2]	-3	hSpCas9	negative selection	504476
43758936	43758959	2	-	26472758	Raji	viability	CAGCAGCACTGTGTCCCCGGAGG	PLEKHH2	ENSG00000152527	0.6433458169120498	[548]	[198]	6	hSpCas9	negative selection	504477
43692642	43692665	2	+	26472758	Raji	viability	GGAATTGCAACTTGAAGAGCAGG	PLEKHH2	ENSG00000152527	1.1539261213106295	[121]	[62]	8	hSpCas9	negative selection	504478
43699823	43699846	2	+	26472758	Raji	viability	GATGAGGAAGACGGGAGCAAAGG	PLEKHH2	ENSG00000152527	-0.4775789653475567	[467]	[77]	-4	hSpCas9	negative selection	504479
43700339	43700362	2	-	26472758	Raji	viability	ATCCTGTCAGAGCTTAACTGTGG	PLEKHH2	ENSG00000152527	0.054560324942533045	[750]	[180]	0	hSpCas9	negative selection	504480
43706388	43706411	2	-	26472758	Raji	viability	CAAAGTTGTATACACTGGGGTGG	PLEKHH2	ENSG00000152527	0.37041794120739335	[69]	[20]	3	hSpCas9	negative selection	504481
43700585	43700608	2	-	26472758	K562	viability	CAAGAAGGAAAACGGTGCAGGGG	PLEKHH2	ENSG00000152527	0.3286700639075808	[581]	[616]	2	hSpCas9	negative selection	695590
43710283	43710306	2	+	26472758	K562	viability	CGGTGGTTTGTTCTTAAAGGTGG	PLEKHH2	ENSG00000152527	0.9425401858024927	[526]	[854]	7	hSpCas9	negative selection	695591
43710263	43710286	2	+	26472758	K562	viability	AAGTCAAGTCTTGGAAGCGGCGG	PLEKHH2	ENSG00000152527	-1.4044159562210945	[507]	[161]	-6	hSpCas9	negative selection	695592
43729670	43729693	2	+	26472758	K562	viability	GGAAGCAACAATGTAAACGTTGG	PLEKHH2	ENSG00000152527	0.5554585064110729	[398]	[494]	4	hSpCas9	negative selection	695593
43743909	43743932	2	-	26472758	K562	viability	AACGCAAATCCAGACTGCGCTGG	PLEKHH2	ENSG00000152527	0.28289287548108266	[36]	[37]	2	hSpCas9	negative selection	695594
43758936	43758959	2	-	26472758	K562	viability	CAGCAGCACTGTGTCCCCGGAGG	PLEKHH2	ENSG00000152527	-0.0005333191838892137	[665]	[561]	0	hSpCas9	negative selection	695595
43692642	43692665	2	+	26472758	K562	viability	GGAATTGCAACTTGAAGAGCAGG	PLEKHH2	ENSG00000152527	0.17667412103061275	[217]	[207]	1	hSpCas9	negative selection	695596
43699823	43699846	2	+	26472758	K562	viability	GATGAGGAAGACGGGAGCAAAGG	PLEKHH2	ENSG00000152527	-1.296277365380568	[1026]	[352]	-6	hSpCas9	negative selection	695597
43700339	43700362	2	-	26472758	K562	viability	ATCCTGTCAGAGCTTAACTGTGG	PLEKHH2	ENSG00000152527	0.7639534091569526	[1044]	[1497]	6	hSpCas9	negative selection	695598
43706388	43706411	2	-	26472758	K562	viability	CAAAGTTGTATACACTGGGGTGG	PLEKHH2	ENSG00000152527	0.6701826335383491	[133]	[179]	5	hSpCas9	negative selection	695599
43697223	43697246	2	-	26627737	DLD1	viability	AGGTCAAACTGCTCAGGCGCTGG	PLEKHH2	ENSG00000152527	0.3365458313443329	[417]	[154,137,195]	3	hSpCas9	negative selection	811999
43700195	43700218	2	-	26627737	DLD1	viability	GGATGCTTTGGCATTAAAGCTGG	PLEKHH2	ENSG00000152527	-0.07652387513260794	[296]	[75,84,100]	-1	hSpCas9	negative selection	812000
43707474	43707497	2	-	26627737	DLD1	viability	TGACTCTGACGTCCGGGAGCTGG	PLEKHH2	ENSG00000152527	-0.5455045696889811	[274]	[80,60,37]	-5	hSpCas9	negative selection	812001
43710034	43710057	2	-	26627737	DLD1	viability	TCTGTGGAGTAAGCATCAGGAGG	PLEKHH2	ENSG00000152527	-0.13120128913501128	[296]	[71,57,117]	-1	hSpCas9	negative selection	812002
43710266	43710289	2	+	26627737	DLD1	viability	TCAAGTCTTGGAAGCGGCGGTGG	PLEKHH2	ENSG00000152527	0.15096510625591314	[460]	[175,228,88]	1	hSpCas9	negative selection	812003
43726354	43726377	2	-	26627737	DLD1	viability	GGATAACAGACTTCGTCCACTGG	PLEKHH2	ENSG00000152527	0.49412789906723736	[272]	[48,171,138]	5	hSpCas9	negative selection	812004
43697223	43697246	2	-	26627737	GBM cells	viability after 5 days	AGGTCAAACTGCTCAGGCGCTGG	PLEKHH2	ENSG00000152527	-0.16717531557208665	[267]	[120,134]	-3	hSpCas9	negative selection	894314
43700195	43700218	2	-	26627737	GBM cells	viability after 5 days	GGATGCTTTGGCATTAAAGCTGG	PLEKHH2	ENSG00000152527	0.027070226376367745	[182]	[110,88]	0	hSpCas9	negative selection	894315
43707474	43707497	2	-	26627737	GBM cells	viability after 5 days	TGACTCTGACGTCCGGGAGCTGG	PLEKHH2	ENSG00000152527	-0.10108612511431447	[124]	[80,43]	-1	hSpCas9	negative selection	894316
43710034	43710057	2	-	26627737	GBM cells	viability after 5 days	TCTGTGGAGTAAGCATCAGGAGG	PLEKHH2	ENSG00000152527	0.3645774472344972	[146]	[91,110]	5	hSpCas9	negative selection	894317
43710266	43710289	2	+	26627737	GBM cells	viability after 5 days	TCAAGTCTTGGAAGCGGCGGTGG	PLEKHH2	ENSG00000152527	0.16551489573967157	[201]	[122,119]	2	hSpCas9	negative selection	894318
43726354	43726377	2	-	26627737	GBM cells	viability after 5 days	GGATAACAGACTTCGTCCACTGG	PLEKHH2	ENSG00000152527	-0.2026241515763767	[205]	[105,85]	-3	hSpCas9	negative selection	894319
43697223	43697246	2	-	26627737	GBM cells	viability after 13 days	AGGTCAAACTGCTCAGGCGCTGG	PLEKHH2	ENSG00000152527	0.5007625535423008	[267]	[261,159]	6	hSpCas9	negative selection	976629
43700195	43700218	2	-	26627737	GBM cells	viability after 13 days	GGATGCTTTGGCATTAAAGCTGG	PLEKHH2	ENSG00000152527	0.5467512624113063	[182]	[165,127]	6	hSpCas9	negative selection	976630
43707474	43707497	2	-	26627737	GBM cells	viability after 13 days	TGACTCTGACGTCCGGGAGCTGG	PLEKHH2	ENSG00000152527	-0.6725440735637191	[124]	[41,42]	-7	hSpCas9	negative selection	976631
43710034	43710057	2	-	26627737	GBM cells	viability after 13 days	TCTGTGGAGTAAGCATCAGGAGG	PLEKHH2	ENSG00000152527	-0.04089740750020454	[146]	[103,55]	0	hSpCas9	negative selection	976632
43710266	43710289	2	+	26627737	GBM cells	viability after 13 days	TCAAGTCTTGGAAGCGGCGGTGG	PLEKHH2	ENSG00000152527	0.295748300863358	[201]	[176,99]	4	hSpCas9	negative selection	976633
43726354	43726377	2	-	26627737	GBM cells	viability after 13 days	GGATAACAGACTTCGTCCACTGG	PLEKHH2	ENSG00000152527	-0.6476450875356168	[205]	[72,69]	-6	hSpCas9	negative selection	976634
43697223	43697246	2	-	26627737	GBM cells	viability after 21 days	AGGTCAAACTGCTCAGGCGCTGG	PLEKHH2	ENSG00000152527	0.20932118607588698	[267]	[183,153]	2	hSpCas9	negative selection	1058944
43700195	43700218	2	-	26627737	GBM cells	viability after 21 days	GGATGCTTTGGCATTAAAGCTGG	PLEKHH2	ENSG00000152527	0.990079966707051	[182]	[197,196]	8	hSpCas9	negative selection	1058945
43707474	43707497	2	-	26627737	GBM cells	viability after 21 days	TGACTCTGACGTCCGGGAGCTGG	PLEKHH2	ENSG00000152527	0.3414591558984911	[124]	[84,86]	3	hSpCas9	negative selection	1058946
43710034	43710057	2	-	26627737	GBM cells	viability after 21 days	TCTGTGGAGTAAGCATCAGGAGG	PLEKHH2	ENSG00000152527	-0.5075113933732778	[146]	[51,59]	-4	hSpCas9	negative selection	1058947
43710266	43710289	2	+	26627737	GBM cells	viability after 21 days	TCAAGTCTTGGAAGCGGCGGTGG	PLEKHH2	ENSG00000152527	0.6444604108656483	[201]	[193,150]	6	hSpCas9	negative selection	1058948
43726354	43726377	2	-	26627737	GBM cells	viability after 21 days	GGATAACAGACTTCGTCCACTGG	PLEKHH2	ENSG00000152527	-0.6188601641804439	[205]	[63,80]	-5	hSpCas9	negative selection	1058949
43697223	43697246	2	-	26627737	RPE1	viability after 9 days	AGGTCAAACTGCTCAGGCGCTGG	PLEKHH2	ENSG00000152527	-0.7077503279607106	[1085]	[136,299]	-5	hSpCas9	negative selection	1141259
43700195	43700218	2	-	26627737	RPE1	viability after 9 days	GGATGCTTTGGCATTAAAGCTGG	PLEKHH2	ENSG00000152527	0.4403047230203627	[515]	[161,292]	3	hSpCas9	negative selection	1141260
43707474	43707497	2	-	26627737	RPE1	viability after 9 days	TGACTCTGACGTCCGGGAGCTGG	PLEKHH2	ENSG00000152527	-0.8289040640925873	[336]	[37,86]	-5	hSpCas9	negative selection	1141261
43710034	43710057	2	-	26627737	RPE1	viability after 9 days	TCTGTGGAGTAAGCATCAGGAGG	PLEKHH2	ENSG00000152527	-0.0003251470870780926	[488]	[211,76]	0	hSpCas9	negative selection	1141262
43710266	43710289	2	+	26627737	RPE1	viability after 9 days	TCAAGTCTTGGAAGCGGCGGTGG	PLEKHH2	ENSG00000152527	0.2762120288992887	[684]	[267,248]	2	hSpCas9	negative selection	1141263
43726354	43726377	2	-	26627737	RPE1	viability after 9 days	GGATAACAGACTTCGTCCACTGG	PLEKHH2	ENSG00000152527	0.904412064516487	[344]	[130,293]	6	hSpCas9	negative selection	1141264
43697223	43697246	2	-	26627737	RPE1	viability after 12 days	AGGTCAAACTGCTCAGGCGCTGG	PLEKHH2	ENSG00000152527	-1.0465169651718154	[1085]	[132,149]	-6	hSpCas9	negative selection	1223574
43700195	43700218	2	-	26627737	RPE1	viability after 12 days	GGATGCTTTGGCATTAAAGCTGG	PLEKHH2	ENSG00000152527	0.6432025638136258	[515]	[182,251]	4	hSpCas9	negative selection	1223575
43707474	43707497	2	-	26627737	RPE1	viability after 12 days	TGACTCTGACGTCCGGGAGCTGG	PLEKHH2	ENSG00000152527	-0.44800294764487947	[336]	[78,52]	-3	hSpCas9	negative selection	1223576
43710034	43710057	2	-	26627737	RPE1	viability after 12 days	TCTGTGGAGTAAGCATCAGGAGG	PLEKHH2	ENSG00000152527	0.7389007893787309	[488]	[278,155]	5	hSpCas9	negative selection	1223577
43710266	43710289	2	+	26627737	RPE1	viability after 12 days	TCAAGTCTTGGAAGCGGCGGTGG	PLEKHH2	ENSG00000152527	0.7433392107906683	[684]	[259,358]	5	hSpCas9	negative selection	1223578
43726354	43726377	2	-	26627737	RPE1	viability after 12 days	GGATAACAGACTTCGTCCACTGG	PLEKHH2	ENSG00000152527	0.5863781109030881	[344]	[110,168]	4	hSpCas9	negative selection	1223579
43697223	43697246	2	-	26627737	RPE1	viability after 15 days	AGGTCAAACTGCTCAGGCGCTGG	PLEKHH2	ENSG00000152527	-1.4552383792222716	[1085]	[109,113]	-7	hSpCas9	negative selection	1305889
43700195	43700218	2	-	26627737	RPE1	viability after 15 days	GGATGCTTTGGCATTAAAGCTGG	PLEKHH2	ENSG00000152527	0.9218697587033351	[515]	[217,332]	5	hSpCas9	negative selection	1305890
43707474	43707497	2	-	26627737	RPE1	viability after 15 days	TGACTCTGACGTCCGGGAGCTGG	PLEKHH2	ENSG00000152527	-0.13491693181801634	[336]	[96,76]	-1	hSpCas9	negative selection	1305891
43710034	43710057	2	-	26627737	RPE1	viability after 15 days	TCTGTGGAGTAAGCATCAGGAGG	PLEKHH2	ENSG00000152527	1.7792439679519207	[488]	[738,219]	8	hSpCas9	negative selection	1305892
43710266	43710289	2	+	26627737	RPE1	viability after 15 days	TCAAGTCTTGGAAGCGGCGGTGG	PLEKHH2	ENSG00000152527	0.7242063102422722	[684]	[313,325]	4	hSpCas9	negative selection	1305893
43726354	43726377	2	-	26627737	RPE1	viability after 15 days	GGATAACAGACTTCGTCCACTGG	PLEKHH2	ENSG00000152527	0.32548083368256253	[344]	[133,110]	2	hSpCas9	negative selection	1305894
43697223	43697246	2	-	26627737	RPE1	viability after 18 days	AGGTCAAACTGCTCAGGCGCTGG	PLEKHH2	ENSG00000152527	-0.878906860886537	[1085]	[140,178]	-5	hSpCas9	negative selection	1388204
43700195	43700218	2	-	26627737	RPE1	viability after 18 days	GGATGCTTTGGCATTAAAGCTGG	PLEKHH2	ENSG00000152527	0.48380641498622523	[515]	[186,202]	3	hSpCas9	negative selection	1388205
43707474	43707497	2	-	26627737	RPE1	viability after 18 days	TGACTCTGACGTCCGGGAGCTGG	PLEKHH2	ENSG00000152527	0.04174844995927507	[336]	[96,89]	0	hSpCas9	negative selection	1388206
43710034	43710057	2	-	26627737	RPE1	viability after 18 days	TCTGTGGAGTAAGCATCAGGAGG	PLEKHH2	ENSG00000152527	1.2542736797374774	[488]	[308,320]	7	hSpCas9	negative selection	1388207
43710266	43710289	2	+	26627737	RPE1	viability after 18 days	TCAAGTCTTGGAAGCGGCGGTGG	PLEKHH2	ENSG00000152527	0.7144608029528545	[684]	[312,292]	4	hSpCas9	negative selection	1388208
43726354	43726377	2	-	26627737	RPE1	viability after 18 days	GGATAACAGACTTCGTCCACTGG	PLEKHH2	ENSG00000152527	0.41765159894197856	[344]	[134,112]	2	hSpCas9	negative selection	1388209
43697223	43697246	2	-	26627737	HeLa	viability after 8 days	AGGTCAAACTGCTCAGGCGCTGG	PLEKHH2	ENSG00000152527	-0.30179380696801034	[429]	[143,162,146]	-3	hSpCas9	negative selection	1470519
43700195	43700218	2	-	26627737	HeLa	viability after 8 days	GGATGCTTTGGCATTAAAGCTGG	PLEKHH2	ENSG00000152527	0.9454749143617389	[267]	[142,320,193]	7	hSpCas9	negative selection	1470520
43707474	43707497	2	-	26627737	HeLa	viability after 8 days	TGACTCTGACGTCCGGGAGCTGG	PLEKHH2	ENSG00000152527	-0.24380997638570545	[229]	[228,10,47]	-2	hSpCas9	negative selection	1470521
43710034	43710057	2	-	26627737	HeLa	viability after 8 days	TCTGTGGAGTAAGCATCAGGAGG	PLEKHH2	ENSG00000152527	0.2227662467389444	[233]	[81,156,109]	2	hSpCas9	negative selection	1470522
43710266	43710289	2	+	26627737	HeLa	viability after 8 days	TCAAGTCTTGGAAGCGGCGGTGG	PLEKHH2	ENSG00000152527	-0.9358324173964357	[622]	[56,170,175]	-7	hSpCas9	negative selection	1470523
43726354	43726377	2	-	26627737	HeLa	viability after 8 days	GGATAACAGACTTCGTCCACTGG	PLEKHH2	ENSG00000152527	-0.6204361193090482	[334]	[53,89,128]	-6	hSpCas9	negative selection	1470524
43697223	43697246	2	-	26627737	HeLa	viability after 12 days	AGGTCAAACTGCTCAGGCGCTGG	PLEKHH2	ENSG00000152527	-0.16827755222692328	[429]	[193,86,201]	-1	hSpCas9	negative selection	1552834
43700195	43700218	2	-	26627737	HeLa	viability after 12 days	GGATGCTTTGGCATTAAAGCTGG	PLEKHH2	ENSG00000152527	0.6247315835908047	[267]	[93,199,212]	5	hSpCas9	negative selection	1552835
43707474	43707497	2	-	26627737	HeLa	viability after 12 days	TGACTCTGACGTCCGGGAGCTGG	PLEKHH2	ENSG00000152527	0.5007408405535658	[229]	[78,85,241]	4	hSpCas9	negative selection	1552836
43710034	43710057	2	-	26627737	HeLa	viability after 12 days	TCTGTGGAGTAAGCATCAGGAGG	PLEKHH2	ENSG00000152527	0.001873398796431669	[233]	[91,118,76]	0	hSpCas9	negative selection	1552837
43710266	43710289	2	+	26627737	HeLa	viability after 12 days	TCAAGTCTTGGAAGCGGCGGTGG	PLEKHH2	ENSG00000152527	-1.1948325381114158	[622]	[74,190,61]	-8	hSpCas9	negative selection	1552838
43726354	43726377	2	-	26627737	HeLa	viability after 12 days	GGATAACAGACTTCGTCCACTGG	PLEKHH2	ENSG00000152527	-0.30579263042654226	[334]	[151,122,60]	-3	hSpCas9	negative selection	1552839
43697223	43697246	2	-	26627737	HeLa	viability after 15 days	AGGTCAAACTGCTCAGGCGCTGG	PLEKHH2	ENSG00000152527	0.7961503170399499	[429]	[420,117,376]	6	hSpCas9	negative selection	1635149
43700195	43700218	2	-	26627737	HeLa	viability after 15 days	GGATGCTTTGGCATTAAAGCTGG	PLEKHH2	ENSG00000152527	-5.092299984943427e-05	[267]	[71,143,111]	0	hSpCas9	negative selection	1635150
43707474	43707497	2	-	26627737	HeLa	viability after 15 days	TGACTCTGACGTCCGGGAGCTGG	PLEKHH2	ENSG00000152527	-0.021810182563065772	[229]	[113,62,99]	0	hSpCas9	negative selection	1635151
43710034	43710057	2	-	26627737	HeLa	viability after 15 days	TCTGTGGAGTAAGCATCAGGAGG	PLEKHH2	ENSG00000152527	0.49622888984765434	[233]	[135,169,93]	4	hSpCas9	negative selection	1635152
43710266	43710289	2	+	26627737	HeLa	viability after 15 days	TCAAGTCTTGGAAGCGGCGGTGG	PLEKHH2	ENSG00000152527	-1.5255607900045933	[622]	[54,93,117]	-8	hSpCas9	negative selection	1635153
43726354	43726377	2	-	26627737	HeLa	viability after 15 days	GGATAACAGACTTCGTCCACTGG	PLEKHH2	ENSG00000152527	-0.5026395091604008	[334]	[106,80,100]	-4	hSpCas9	negative selection	1635154
43697223	43697246	2	-	26627737	HeLa	viability after 18 days	AGGTCAAACTGCTCAGGCGCTGG	PLEKHH2	ENSG00000152527	0.862800642877651	[429]	[310,96,376]	6	hSpCas9	negative selection	1717464
43700195	43700218	2	-	26627737	HeLa	viability after 18 days	GGATGCTTTGGCATTAAAGCTGG	PLEKHH2	ENSG00000152527	0.020883165031282847	[267]	[49,120,111]	0	hSpCas9	negative selection	1717465
43707474	43707497	2	-	26627737	HeLa	viability after 18 days	TGACTCTGACGTCCGGGAGCTGG	PLEKHH2	ENSG00000152527	-0.009182121124936105	[229]	[78,50,99]	0	hSpCas9	negative selection	1717466
43710034	43710057	2	-	26627737	HeLa	viability after 18 days	TCTGTGGAGTAAGCATCAGGAGG	PLEKHH2	ENSG00000152527	0.48924009730762424	[233]	[88,141,93]	4	hSpCas9	negative selection	1717467
43710266	43710289	2	+	26627737	HeLa	viability after 18 days	TCAAGTCTTGGAAGCGGCGGTGG	PLEKHH2	ENSG00000152527	-1.49862621705941	[622]	[35,82,117]	-8	hSpCas9	negative selection	1717468
43726354	43726377	2	-	26627737	HeLa	viability after 18 days	GGATAACAGACTTCGTCCACTGG	PLEKHH2	ENSG00000152527	-0.5580066760385481	[334]	[67,62,100]	-5	hSpCas9	negative selection	1717469
43697223	43697246	2	-	26627737	HCT116	viability after 6 days	AGGTCAAACTGCTCAGGCGCTGG	PLEKHH2	ENSG00000152527	-0.2472587718627514	[854]	[129,103]	-1	hSpCas9	negative selection	1799779
43700195	43700218	2	-	26627737	HCT116	viability after 6 days	GGATGCTTTGGCATTAAAGCTGG	PLEKHH2	ENSG00000152527	-0.5769398162532873	[446]	[59,39]	-3	hSpCas9	negative selection	1799780
43707474	43707497	2	-	26627737	HCT116	viability after 6 days	TGACTCTGACGTCCGGGAGCTGG	PLEKHH2	ENSG00000152527	0.5368887606580806	[286]	[107,41]	3	hSpCas9	negative selection	1799781
43710034	43710057	2	-	26627737	HCT116	viability after 6 days	TCTGTGGAGTAAGCATCAGGAGG	PLEKHH2	ENSG00000152527	-0.6230815099764548	[779]	[116,58]	-4	hSpCas9	negative selection	1799782
43710266	43710289	2	+	26627737	HCT116	viability after 6 days	TCAAGTCTTGGAAGCGGCGGTGG	PLEKHH2	ENSG00000152527	1.7375968443746415	[582]	[197,364]	8	hSpCas9	negative selection	1799783
43726354	43726377	2	-	26627737	HCT116	viability after 6 days	GGATAACAGACTTCGTCCACTGG	PLEKHH2	ENSG00000152527	-0.8535693043833441	[559]	[127,4]	-5	hSpCas9	negative selection	1799784
43697223	43697246	2	-	26627737	HCT116	viability after 8 days	AGGTCAAACTGCTCAGGCGCTGG	PLEKHH2	ENSG00000152527	1.14431421797191	[154]	[211,183,170]	8	hSpCas9	negative selection	1882094
43700195	43700218	2	-	26627737	HCT116	viability after 8 days	GGATGCTTTGGCATTAAAGCTGG	PLEKHH2	ENSG00000152527	0.4410717352877417	[226]	[262,151,96]	4	hSpCas9	negative selection	1882095
43707474	43707497	2	-	26627737	HCT116	viability after 8 days	TGACTCTGACGTCCGGGAGCTGG	PLEKHH2	ENSG00000152527	1.3085376212581616	[86]	[158,83,113]	9	hSpCas9	negative selection	1882096
43710034	43710057	2	-	26627737	HCT116	viability after 8 days	TCTGTGGAGTAAGCATCAGGAGG	PLEKHH2	ENSG00000152527	-0.6497776256730533	[260]	[93,85,94]	-7	hSpCas9	negative selection	1882097
43710266	43710289	2	+	26627737	HCT116	viability after 8 days	TCAAGTCTTGGAAGCGGCGGTGG	PLEKHH2	ENSG00000152527	0.3463842375493643	[364]	[159,233,369]	4	hSpCas9	negative selection	1882098
43726354	43726377	2	-	26627737	HCT116	viability after 8 days	GGATAACAGACTTCGTCCACTGG	PLEKHH2	ENSG00000152527	-0.38355112311775147	[250]	[133,114,69]	-4	hSpCas9	negative selection	1882099
43697223	43697246	2	-	26627737	HCT116	viability after 9 days	AGGTCAAACTGCTCAGGCGCTGG	PLEKHH2	ENSG00000152527	0.42102462445410654	[854]	[594,76]	3	hSpCas9	negative selection	1964409
43700195	43700218	2	-	26627737	HCT116	viability after 9 days	GGATGCTTTGGCATTAAAGCTGG	PLEKHH2	ENSG00000152527	0.5971817862593928	[446]	[179,180]	4	hSpCas9	negative selection	1964410
43707474	43707497	2	-	26627737	HCT116	viability after 9 days	TGACTCTGACGTCCGGGAGCTGG	PLEKHH2	ENSG00000152527	-0.8096718369081273	[286]	[12,67]	-5	hSpCas9	negative selection	1964411
43710034	43710057	2	-	26627737	HCT116	viability after 9 days	TCTGTGGAGTAAGCATCAGGAGG	PLEKHH2	ENSG00000152527	-2.014452586423065	[779]	[31,66]	-8	hSpCas9	negative selection	1964412
43710266	43710289	2	+	26627737	HCT116	viability after 9 days	TCAAGTCTTGGAAGCGGCGGTGG	PLEKHH2	ENSG00000152527	0.0479894076253397	[582]	[275,69]	0	hSpCas9	negative selection	1964413
43726354	43726377	2	-	26627737	HCT116	viability after 9 days	GGATAACAGACTTCGTCCACTGG	PLEKHH2	ENSG00000152527	-0.3030687647769198	[559]	[228,35]	-2	hSpCas9	negative selection	1964414
43697223	43697246	2	-	26627737	HCT116	viability after 12 days	AGGTCAAACTGCTCAGGCGCTGG	PLEKHH2	ENSG00000152527	1.6624572659991554	[154]	[222,231,320]	9	hSpCas9	negative selection	2046724
43700195	43700218	2	-	26627737	HCT116	viability after 12 days	GGATGCTTTGGCATTAAAGCTGG	PLEKHH2	ENSG00000152527	0.4180735910697571	[226]	[179,143,151]	4	hSpCas9	negative selection	2046725
43707474	43707497	2	-	26627737	HCT116	viability after 12 days	TGACTCTGACGTCCGGGAGCTGG	PLEKHH2	ENSG00000152527	1.0695148299311874	[86]	[96,63,125]	8	hSpCas9	negative selection	2046726
43710034	43710057	2	-	26627737	HCT116	viability after 12 days	TCTGTGGAGTAAGCATCAGGAGG	PLEKHH2	ENSG00000152527	-1.4110614287245224	[260]	[36,50,67]	-8	hSpCas9	negative selection	2046727
43710266	43710289	2	+	26627737	HCT116	viability after 12 days	TCAAGTCTTGGAAGCGGCGGTGG	PLEKHH2	ENSG00000152527	-0.3523709018357277	[364]	[129,210,112]	-4	hSpCas9	negative selection	2046728
43726354	43726377	2	-	26627737	HCT116	viability after 12 days	GGATAACAGACTTCGTCCACTGG	PLEKHH2	ENSG00000152527	-0.5791452304266769	[250]	[43,138,86]	-6	hSpCas9	negative selection	2046729
43697223	43697246	2	-	26627737	HCT116	viability after 15 days	AGGTCAAACTGCTCAGGCGCTGG	PLEKHH2	ENSG00000152527	1.2740013533094439	[154]	[284,212,156]	8	hSpCas9	negative selection	2129039
43700195	43700218	2	-	26627737	HCT116	viability after 15 days	GGATGCTTTGGCATTAAAGCTGG	PLEKHH2	ENSG00000152527	0.49569665754012515	[226]	[234,165,156]	5	hSpCas9	negative selection	2129040
43707474	43707497	2	-	26627737	HCT116	viability after 15 days	TGACTCTGACGTCCGGGAGCTGG	PLEKHH2	ENSG00000152527	1.2919967777956802	[86]	[150,136,82]	8	hSpCas9	negative selection	2129041
43710034	43710057	2	-	26627737	HCT116	viability after 15 days	TCTGTGGAGTAAGCATCAGGAGG	PLEKHH2	ENSG00000152527	-0.5368707460079154	[260]	[80,103,121]	-5	hSpCas9	negative selection	2129042
43710266	43710289	2	+	26627737	HCT116	viability after 15 days	TCAAGTCTTGGAAGCGGCGGTGG	PLEKHH2	ENSG00000152527	0.046959521453627195	[364]	[264,210,179]	0	hSpCas9	negative selection	2129043
43726354	43726377	2	-	26627737	HCT116	viability after 15 days	GGATAACAGACTTCGTCCACTGG	PLEKHH2	ENSG00000152527	-0.47295456712340916	[250]	[106,104,99]	-5	hSpCas9	negative selection	2129044
43697223	43697246	2	-	26627737	HCT116	viability after 18 days	AGGTCAAACTGCTCAGGCGCTGG	PLEKHH2	ENSG00000152527	1.6139855739381064	[154]	[332,204,147]	9	hSpCas9	negative selection	2211354
43700195	43700218	2	-	26627737	HCT116	viability after 18 days	GGATGCTTTGGCATTAAAGCTGG	PLEKHH2	ENSG00000152527	0.6226754932369064	[226]	[211,124,172]	5	hSpCas9	negative selection	2211355
43707474	43707497	2	-	26627737	HCT116	viability after 18 days	TGACTCTGACGTCCGGGAGCTGG	PLEKHH2	ENSG00000152527	0.795520229316647	[86]	[56,53,110]	6	hSpCas9	negative selection	2211356
43710034	43710057	2	-	26627737	HCT116	viability after 18 days	TCTGTGGAGTAAGCATCAGGAGG	PLEKHH2	ENSG00000152527	-1.1460146533209645	[260]	[15,99,51]	-7	hSpCas9	negative selection	2211357
43710266	43710289	2	+	26627737	HCT116	viability after 18 days	TCAAGTCTTGGAAGCGGCGGTGG	PLEKHH2	ENSG00000152527	-0.13515580407032754	[364]	[155,102,229]	-1	hSpCas9	negative selection	2211358
43726354	43726377	2	-	26627737	HCT116	viability after 18 days	GGATAACAGACTTCGTCCACTGG	PLEKHH2	ENSG00000152527	-0.5653899792422092	[250]	[106,28,114]	-5	hSpCas9	negative selection	2211359
43705670	43705693	2	+	25494202	A375	resistance to PLX-4720 (puromycin)	GTAGTGCAGTGGCATGATCTCGG	PLEKHH2	ENSG00000152527	4.4920303546425915	[16,7]	[10,119]	9	dCas9-VP64	positive selection	2391312
43676491	43676514	2	+	25494202	A375	resistance to PLX-4720 (puromycin)	CGGCCACTGCGGGTGGGGTCCGG	PLEKHH2	ENSG00000152527	0.6783894692803039	[36,25]	[2,19]	3	dCas9-VP64	positive selection	2396226
43676413	43676436	2	-	25494202	A375	resistance to PLX-4720 (puromycin)	GCAGCTAGAGTGGCCCAACCGGG	PLEKHH2	ENSG00000152527	0.3849484260445416	[47,276]	[39,53]	1	dCas9-VP64	positive selection	2396227
43676444	43676467	2	+	25494202	A375	resistance to PLX-4720 (puromycin)	GCTTCTCGGTGGCGTAGAGAAGG	PLEKHH2	ENSG00000152527	2.609320759337336	[16,25]	[41,14]	8	dCas9-VP64	positive selection	2396228
43758528	43758551	2	+	25494202	A375	resistance to PLX-4720 (puromycin)	CAGGCGTGAGCCACTGCACCGGG	PLEKHH2	ENSG00000152527	0.9550246130222104	[38,14]	[18,2]	4	dCas9-VP64	positive selection	2414101
43698275	43698298	2	+	25494202	A375	resistance to PLX-4720 (puromycin)	TCTCACTCTGTCTCCCAGGCCGG	PLEKHH2	ENSG00000152527	-0.22926698104333687	[120,197]	[15,43]	-1	dCas9-VP64	positive selection	2418663
43742073	43742096	2	+	25494202	A375	resistance to PLX-4720 (puromycin)	TCACTGCAACCTCCACCTCCAAG	PLEKHH2	ENSG00000152527	0.058421953785092295	[801,622]	[115,212]	0	dCas9-VP64	positive selection	2420272
43742074	43742097	2	+	25494202	A375	resistance to PLX-4720 (puromycin)	CACTGCAACCTCCACCTCCAAGG	PLEKHH2	ENSG00000152527	-1.6046460755717478	[271,391]	[12,34]	-8	dCas9-VP64	positive selection	2428027
43654899	43654922	2	+	25494202	A375	resistance to PLX-4720 (puromycin)	CGCCAGTAGTCCCAGCTACTCAG	PLEKHH2	ENSG00000152527	1.7407213706869107	[8,18]	[8,10]	6	dCas9-VP64	positive selection	2429269
43711629	43711652	2	+	25494202	A375	resistance to PLX-4720 (puromycin)	CGCCTGTAATCTCAGCACTTCAG	PLEKHH2	ENSG00000152527	-0.6796005969874881	[92,259]	[10,38]	-3	dCas9-VP64	positive selection	2447614
43711859	43711882	2	+	25494202	A375	resistance to PLX-4720 (puromycin)	ACTCCAGCCTGGGCGACAGAAAG	PLEKHH2	ENSG00000152527	1.2012671036636573	[14,1]	[1,5]	5	dCas9-VP64	positive selection	2454916
43705670	43705693	2	+	25494202	A375	resistance to PLX-4720 (zeocin)	GTAGTGCAGTGGCATGATCTCGG	PLEKHH2	ENSG00000152527	0.570567911377349	[309,79]	[100,89]	4	dCas9-VP64	positive selection	2486567
43676491	43676514	2	+	25494202	A375	resistance to PLX-4720 (zeocin)	CGGCCACTGCGGGTGGGGTCCGG	PLEKHH2	ENSG00000152527	-0.5154338651218313	[47,53]	[7,13]	-5	dCas9-VP64	positive selection	2491481
43676413	43676436	2	-	25494202	A375	resistance to PLX-4720 (zeocin)	GCAGCTAGAGTGGCCCAACCGGG	PLEKHH2	ENSG00000152527	-0.46334102280850464	[552,110]	[127,33]	-5	dCas9-VP64	positive selection	2491482
43676444	43676467	2	+	25494202	A375	resistance to PLX-4720 (zeocin)	GCTTCTCGGTGGCGTAGAGAAGG	PLEKHH2	ENSG00000152527	1.4818200381964977	[55,188]	[23,191]	8	dCas9-VP64	positive selection	2491483
43758528	43758551	2	+	25494202	A375	resistance to PLX-4720 (zeocin)	CAGGCGTGAGCCACTGCACCGGG	PLEKHH2	ENSG00000152527	-0.28279012529460834	[51,110]	[30,11]	-3	dCas9-VP64	positive selection	2509356
43698275	43698298	2	+	25494202	A375	resistance to PLX-4720 (zeocin)	TCTCACTCTGTCTCCCAGGCCGG	PLEKHH2	ENSG00000152527	-0.22012594312438807	[153,72]	[52,11]	-2	dCas9-VP64	positive selection	2513918
43742073	43742096	2	+	25494202	A375	resistance to PLX-4720 (zeocin)	TCACTGCAACCTCCACCTCCAAG	PLEKHH2	ENSG00000152527	0.1281772646791315	[789,694]	[166,357]	1	dCas9-VP64	positive selection	2515527
43742074	43742097	2	+	25494202	A375	resistance to PLX-4720 (zeocin)	CACTGCAACCTCCACCTCCAAGG	PLEKHH2	ENSG00000152527	1.7619180919574486	[222,108]	[343,36]	8	dCas9-VP64	positive selection	2523282
43654899	43654922	2	+	25494202	A375	resistance to PLX-4720 (zeocin)	CGCCAGTAGTCCCAGCTACTCAG	PLEKHH2	ENSG00000152527	0.9029000398623505	[85,44]	[24,53]	6	dCas9-VP64	positive selection	2524524
43711629	43711652	2	+	25494202	A375	resistance to PLX-4720 (zeocin)	CGCCTGTAATCTCAGCACTTCAG	PLEKHH2	ENSG00000152527	0.2134968510682193	[79,136]	[55,26]	1	dCas9-VP64	positive selection	2542869
43711859	43711882	2	+	25494202	A375	resistance to PLX-4720 (zeocin)	ACTCCAGCCTGGGCGACAGAAAG	PLEKHH2	ENSG00000152527	0.32779538109836626	[14,14]	[4,6]	2	dCas9-VP64	positive selection	2550171
43699722	43699745	2	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	ATTCTGTTCTGAGCCACAAGGGG	PLEKHH2	ENSG00000152527	0.192102724277384	[5,4]	[4,5]	4	hSpCas9	positive selection	3011948
43710493	43710516	2	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GATGTAATTAGAAAACCCCAGGG	PLEKHH2	ENSG00000152527	-0.23839218387084202	[2,2]	[2,1]	-3	hSpCas9	positive selection	3011949
43644678	43644701	2	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCAGAGCTTTCTGAGCCAGAGGG	PLEKHH2	ENSG00000152527	0.2488594956949967	[3,3]	[4,2]	5	hSpCas9	positive selection	3011950
43710239	43710262	2	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GGTTATTTATTAAAAATGAGTGG	PLEKHH2	ENSG00000152527	0.18117292896248194	[4,5]	[4,5]	4	hSpCas9	positive selection	3011951
43699722	43699745	2	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	ATTCTGTTCTGAGCCACAAGGGG	PLEKHH2	ENSG00000152527	0.04336684910063032	[5,5]	[3,3]	0	hSpCas9	positive selection	3079806
43710493	43710516	2	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GATGTAATTAGAAAACCCCAGGG	PLEKHH2	ENSG00000152527	0.48232510331322975	[2,2]	[2,3]	7	hSpCas9	positive selection	3079807
43644678	43644701	2	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCAGAGCTTTCTGAGCCAGAGGG	PLEKHH2	ENSG00000152527	0.3950801663694563	[3,3]	[3,3]	7	hSpCas9	positive selection	3079808
43710239	43710262	2	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GGTTATTTATTAAAAATGAGTGG	PLEKHH2	ENSG00000152527	0.3114936044284989	[4,4]	[5,3]	5	hSpCas9	positive selection	3079809
43678904	43678927		+	24336571	A375	resistance to PLX after 7 days	AGCAGAAAAAGCTTTTCAACAGG	PLEKHH2	ENSG00000152527	-0.10660540244211347	[8,8]	[6,8]	-3	hSpCas9	positive selection	3136213
43644739	43644762		-	24336571	A375	resistance to PLX after 7 days	GAACTCTAAATTTCATGAGTTGG	PLEKHH2	ENSG00000152527	0.30697533492517315	[5,4]	[5,7]	8	hSpCas9	positive selection	3136214
43678904	43678927		+	24336571	A375	resistance to PLX after 14 days	AGCAGAAAAAGCTTTTCAACAGG	PLEKHH2	ENSG00000152527	1.3586182520664187	[8,8]	[9,11]	8	hSpCas9	positive selection	3194006
43644739	43644762		-	24336571	A375	resistance to PLX after 14 days	GAACTCTAAATTTCATGAGTTGG	PLEKHH2	ENSG00000152527	-0.0065774384700678645	[6,4]	[2,1]	0	hSpCas9	positive selection	3194007
43678904	43678927		+	24336571	A375	viability after 7 days	AGCAGAAAAAGCTTTTCAACAGG	PLEKHH2	ENSG00000152527	-0.042561320750601095	[9]	[8,8]	0	hSpCas9	negative selection	3251799
43644739	43644762		-	24336571	A375	viability after 7 days	GAACTCTAAATTTCATGAGTTGG	PLEKHH2	ENSG00000152527	-0.4755945061488379	[7]	[5,4]	-6	hSpCas9	negative selection	3251800
43678904	43678927		+	24336571	A375	viability after 14 days	AGCAGAAAAAGCTTTTCAACAGG	PLEKHH2	ENSG00000152527	0.023875467654588367	[9]	[8,8]	0	hSpCas9	negative selection	3309592
43644739	43644762		-	24336571	A375	viability after 14 days	GAACTCTAAATTTCATGAGTTGG	PLEKHH2	ENSG00000152527	-0.3530808282927488	[7]	[6,4]	-4	hSpCas9	negative selection	3309593
43644739	43644762	2	-	27383988	293T	resistance to West Nile virus (flavivirus)	GAACTCTAAATTTCATGAGTTGG	PLEKHH2	ENSG00000152527	0.2915419267837481	[124,124]	[0,0]	1	hSpCas9	positive selection	3386324
43644676	43644699	2	+	27383988	293T	resistance to West Nile virus (flavivirus)	GGCAGAGCTTTCTGAGCCAGAGG	PLEKHH2	ENSG00000152527	1.0093986980022496	[75,75]	[0,0]	4	hSpCas9	positive selection	3386325
43699722	43699745	2	-	26780180	HT29	viability (Avana library 4 designs)	ATTCTGTTCTGAGCCACAAGGGG	PLEKHH2	ENSG00000152527	0.312601834835682	[]	[]	1	hSpCas9	negative selection	3450043
43710492	43710515	2	+	26780180	HT29	viability (Avana library 4 designs)	GATGTAATTAGAAAACCCCAGGG	PLEKHH2	ENSG00000152527	1.5849038643903	[]	[]	6	hSpCas9	negative selection	3450044
43644677	43644700	2	+	26780180	HT29	viability (Avana library 4 designs)	GCAGAGCTTTCTGAGCCAGAGGG	PLEKHH2	ENSG00000152527	1.23343524999141	[]	[]	5	hSpCas9	negative selection	3450045
43710238	43710261	2	+	26780180	HT29	viability (Avana library 4 designs)	GGTTATTTATTAAAAATGAGTGG	PLEKHH2	ENSG00000152527	0.214750315339921	[]	[]	0	hSpCas9	negative selection	3450046
43710492	43710515	2	+	26780180	A375	viability (Avana lentiCRISPRv2)	GATGTAATTAGAAAACCCCAGGG	PLEKHH2	ENSG00000152527	-8.1933899418342	[]	[]	-7	hSpCas9	negative selection	3545095
43644677	43644700	2	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCAGAGCTTTCTGAGCCAGAGGG	PLEKHH2	ENSG00000152527	0.261067010392206	[]	[]	0	hSpCas9	negative selection	3545096
43710238	43710261	2	+	26780180	A375	viability (Avana lentiCRISPRv2)	GGTTATTTATTAAAAATGAGTGG	PLEKHH2	ENSG00000152527	-19.1767049628634	[]	[]	-9	hSpCas9	negative selection	3545097
43699722	43699745	2	-	26780180	A375	viability (Avana lentiCRISPRv2)	ATTCTGTTCTGAGCCACAAGGGG	PLEKHH2	ENSG00000152527	-0.583575308079578	[]	[]	0	hSpCas9	negative selection	3545098
43699679	43699702	2	+	26780180	A375	viability (Avana lentiCRISPRv2)	CAAGTTCTAGAAAACAACAGAGG	PLEKHH2	ENSG00000152527	-2.22287236629716	[]	[]	-3	hSpCas9	negative selection	3545099
43700008	43700031	2	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCTATATTCTTGGCAGCAGGAGG	PLEKHH2	ENSG00000152527	4.83651719600105	[]	[]	8	hSpCas9	negative selection	3545100
43710492	43710515	2	+	26780180	A375	viability (Avana lentiGuide)	GATGTAATTAGAAAACCCCAGGG	PLEKHH2	ENSG00000152527	-1.65583984742364	[]	[]	-3	hSpCas9	negative selection	3653754
43644677	43644700	2	+	26780180	A375	viability (Avana lentiGuide)	GCAGAGCTTTCTGAGCCAGAGGG	PLEKHH2	ENSG00000152527	-3.49750272338386	[]	[]	-6	hSpCas9	negative selection	3653755
43710238	43710261	2	+	26780180	A375	viability (Avana lentiGuide)	GGTTATTTATTAAAAATGAGTGG	PLEKHH2	ENSG00000152527	-8.15918455763124	[]	[]	-9	hSpCas9	negative selection	3653756
43699722	43699745	2	-	26780180	A375	viability (Avana lentiGuide)	ATTCTGTTCTGAGCCACAAGGGG	PLEKHH2	ENSG00000152527	2.69628995358967	[]	[]	3	hSpCas9	negative selection	3653757
43699679	43699702	2	+	26780180	A375	viability (Avana lentiGuide)	CAAGTTCTAGAAAACAACAGAGG	PLEKHH2	ENSG00000152527	2.41636296274011	[]	[]	2	hSpCas9	negative selection	3653758
43700008	43700031	2	+	26780180	A375	viability (Avana lentiGuide)	GCTATATTCTTGGCAGCAGGAGG	PLEKHH2	ENSG00000152527	-0.314285033158118	[]	[]	0	hSpCas9	negative selection	3653759
43710492	43710515	2	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GATGTAATTAGAAAACCCCAGGG	PLEKHH2	ENSG00000152527	-0.883787867376532	[6]	[2,3]	-8	hSpCas9	positive selection	3762413
43644677	43644700	2	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCAGAGCTTTCTGAGCCAGAGGG	PLEKHH2	ENSG00000152527	-0.088838921827181	[4]	[4,3]	-1	hSpCas9	positive selection	3762414
43710238	43710261	2	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGTTATTTATTAAAAATGAGTGG	PLEKHH2	ENSG00000152527	-1.0115743223739875	[10]	[5,3]	-8	hSpCas9	positive selection	3762415
43699722	43699745	2	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ATTCTGTTCTGAGCCACAAGGGG	PLEKHH2	ENSG00000152527	0.009932701188785698	[6]	[6,6]	0	hSpCas9	positive selection	3762416
43699679	43699702	2	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CAAGTTCTAGAAAACAACAGAGG	PLEKHH2	ENSG00000152527	-0.6425735232493173	[5]	[3,3]	-7	hSpCas9	positive selection	3762417
43700008	43700031	2	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCTATATTCTTGGCAGCAGGAGG	PLEKHH2	ENSG00000152527	0.03678397122500728	[5]	[5,4]	0	hSpCas9	positive selection	3762418
43710492	43710515	2	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GATGTAATTAGAAAACCCCAGGG	PLEKHH2	ENSG00000152527	0.12880198553718125	[4]	[3,4]	3	hSpCas9	positive selection	3871020
43644677	43644700	2	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCAGAGCTTTCTGAGCCAGAGGG	PLEKHH2	ENSG00000152527	-0.2147871562115276	[5]	[2,4]	-3	hSpCas9	positive selection	3871021
43710238	43710261	2	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGTTATTTATTAAAAATGAGTGG	PLEKHH2	ENSG00000152527	0.41965555466080573	[6]	[7,7]	9	hSpCas9	positive selection	3871022
43699722	43699745	2	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ATTCTGTTCTGAGCCACAAGGGG	PLEKHH2	ENSG00000152527	0.13490187189204966	[7]	[6,6]	3	hSpCas9	positive selection	3871023
43699679	43699702	2	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CAAGTTCTAGAAAACAACAGAGG	PLEKHH2	ENSG00000152527	0.01629192203176516	[4]	[4,3]	0	hSpCas9	positive selection	3871024
43700008	43700031	2	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCTATATTCTTGGCAGCAGGAGG	PLEKHH2	ENSG00000152527	0.2312507036373513	[5]	[5,5]	6	hSpCas9	positive selection	3871025
43694471	43694494	2	+	26780180	A375	viability	AAGCAGCTAAGATAAAAGAATGG	PLEKHH2	ENSG00000152527	0.716910922285349	[]	[]	2	hSpCas9	negative selection	3981858
43644701	43644724	2	-	26780180	A375	viability	CATCGTTCCTTCCAATCTACTGG	PLEKHH2	ENSG00000152527	1.08476067778076	[]	[]	5	hSpCas9	negative selection	3981859
43644739	43644762	2	-	26780180	A375	viability	GAACTCTAAATTTCATGAGTTGG	PLEKHH2	ENSG00000152527	1.09085655151664	[]	[]	5	hSpCas9	negative selection	3981860
43644712	43644735	2	+	26780180	A375	viability	GAAGGAACGATGTGTAGCTCTGG	PLEKHH2	ENSG00000152527	1.19708353330466	[]	[]	6	hSpCas9	negative selection	3981861
43644676	43644699	2	+	26780180	A375	viability	GGCAGAGCTTTCTGAGCCAGAGG	PLEKHH2	ENSG00000152527	0.833226707585412	[]	[]	3	hSpCas9	negative selection	3981862
43694471	43694494	2	+	26780180	HT29	viability (GeCKOv2 library)	AAGCAGCTAAGATAAAAGAATGG	PLEKHH2	ENSG00000152527	0.943809088295789	[]	[]	4	hSpCas9	negative selection	4089824
43644701	43644724	2	-	26780180	HT29	viability (GeCKOv2 library)	CATCGTTCCTTCCAATCTACTGG	PLEKHH2	ENSG00000152527	1.2506960504176	[]	[]	6	hSpCas9	negative selection	4089825
43644739	43644762	2	-	26780180	HT29	viability (GeCKOv2 library)	GAACTCTAAATTTCATGAGTTGG	PLEKHH2	ENSG00000152527	0.796910243932582	[]	[]	3	hSpCas9	negative selection	4089826
43644712	43644735	2	+	26780180	HT29	viability (GeCKOv2 library)	GAAGGAACGATGTGTAGCTCTGG	PLEKHH2	ENSG00000152527	0.79024132143392	[]	[]	3	hSpCas9	negative selection	4089827
43644676	43644699	2	+	26780180	HT29	viability (GeCKOv2 library)	GGCAGAGCTTTCTGAGCCAGAGG	PLEKHH2	ENSG00000152527	0.714500103070367	[]	[]	2	hSpCas9	negative selection	4089828
43678904	43678927	2	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	AGCAGAAAAAGCTTTTCAACAGG	PLEKHH2	ENSG00000152527	0.37278713127790797	[2]	[0,3]	8	hSpCas9	positive selection	4161222
43644739	43644762	2	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GAACTCTAAATTTCATGAGTTGG	PLEKHH2	ENSG00000152527	-0.15721353893086681	[2]	[1,0]	-4	hSpCas9	positive selection	4161223
43678904	43678927	2	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	AGCAGAAAAAGCTTTTCAACAGG	PLEKHH2	ENSG00000152527	1.0809750806117095	[3]	[1,0,0,4]	7	hSpCas9	positive selection	4225244
43644739	43644762	2	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GAACTCTAAATTTCATGAGTTGG	PLEKHH2	ENSG00000152527	-0.19747401909198262	[3]	[4,0,0,0]	-3	hSpCas9	positive selection	4225245
43644701	43644724	2	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CATCGTTCCTTCCAATCTACTGG	PLEKHH2	ENSG00000152527	0.3310425831215385	[3]	[3,2]	6	hSpCas9	positive selection	4290777
43644712	43644735	2	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GAAGGAACGATGTGTAGCTCTGG	PLEKHH2	ENSG00000152527	-0.17927677639818534	[3]	[3,0]	-4	hSpCas9	positive selection	4290778
43694471	43694494	2	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AAGCAGCTAAGATAAAAGAATGG	PLEKHH2	ENSG00000152527	-0.47185652917399545	[1]	[0,0]	-8	hSpCas9	positive selection	4290779
43644739	43644762	2	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GAACTCTAAATTTCATGAGTTGG	PLEKHH2	ENSG00000152527	0.1758613685277457	[2]	[2,1]	3	hSpCas9	positive selection	4355029
43644676	43644699	2	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GGCAGAGCTTTCTGAGCCAGAGG	PLEKHH2	ENSG00000152527	-0.02891073836627922	[1]	[2,0]	0	hSpCas9	positive selection	4355030
43692595	43692617	2	+	27760321	OCIAML3	viability	GATCTGGAGTCGCTAATACAGG	PLEKHH2	ENSG00000152527	-1.0351450698659632	[249,232]	[53,141]	-7	hSpCas9	negative selection	4428593
43697201	43697223	2	+	27760321	OCIAML3	viability	CTACACTAAAGCTTTCGGAAGG	PLEKHH2	ENSG00000152527	0.4105037081009404	[509,413]	[419,552]	5	hSpCas9	negative selection	4428594
43700305	43700327	2	+	27760321	OCIAML3	viability	AAGTGTAGCACTAGCCAAAAGG	PLEKHH2	ENSG00000152527	1.1784144942386354	[114,92]	[242,104]	9	hSpCas9	negative selection	4428595
43700393	43700415	2	+	27760321	OCIAML3	viability	ATACGACCACTGAGACCTCAGG	PLEKHH2	ENSG00000152527	0.46788133514377106	[437,347]	[382,473]	5	hSpCas9	negative selection	4428596
43707528	43707550	2	-	27760321	OCIAML3	viability	TCACCTCGTTTCATGGCTCTGG	PLEKHH2	ENSG00000152527	0.5651692171055096	[2042,1850]	[1962,2626]	6	hSpCas9	negative selection	4428597
43692595	43692617	2	+	27760321	OCIAML2	viability	GATCTGGAGTCGCTAATACAGG	PLEKHH2	ENSG00000152527	0.14429325449735209	[249,232]	[215,215]	2	hSpCas9	negative selection	4512056
43697201	43697223	2	+	27760321	OCIAML2	viability	CTACACTAAAGCTTTCGGAAGG	PLEKHH2	ENSG00000152527	-0.03756970029503756	[509,413]	[287,459]	0	hSpCas9	negative selection	4512057
43700305	43700327	2	+	27760321	OCIAML2	viability	AAGTGTAGCACTAGCCAAAAGG	PLEKHH2	ENSG00000152527	1.118483799342344	[114,92]	[144,229]	9	hSpCas9	negative selection	4512058
43700393	43700415	2	+	27760321	OCIAML2	viability	ATACGACCACTGAGACCTCAGG	PLEKHH2	ENSG00000152527	0.9714095726147011	[437,347]	[496,780]	9	hSpCas9	negative selection	4512059
43707528	43707550	2	-	27760321	OCIAML2	viability	TCACCTCGTTTCATGGCTCTGG	PLEKHH2	ENSG00000152527	0.6236710106395735	[2042,1850]	[2137,2802]	8	hSpCas9	negative selection	4512060
43692595	43692617	2	+	27760321	MV411	viability	GATCTGGAGTCGCTAATACAGG	PLEKHH2	ENSG00000152527	1.8789171223701135	[249,232]	[800,263]	9	hSpCas9	negative selection	4595519
43697201	43697223	2	+	27760321	MV411	viability	CTACACTAAAGCTTTCGGAAGG	PLEKHH2	ENSG00000152527	-0.8547326402408912	[509,413]	[48,345]	-5	hSpCas9	negative selection	4595520
43700305	43700327	2	+	27760321	MV411	viability	AAGTGTAGCACTAGCCAAAAGG	PLEKHH2	ENSG00000152527	0.4426006298305676	[114,92]	[53,150]	3	hSpCas9	negative selection	4595521
43700393	43700415	2	+	27760321	MV411	viability	ATACGACCACTGAGACCTCAGG	PLEKHH2	ENSG00000152527	-1.0800028339048877	[437,347]	[31,256]	-6	hSpCas9	negative selection	4595522
43707528	43707550	2	-	27760321	MV411	viability	TCACCTCGTTTCATGGCTCTGG	PLEKHH2	ENSG00000152527	0.1512833301676788	[2042,1850]	[1165,1815]	1	hSpCas9	negative selection	4595523
43692595	43692617	2	+	27760321	HL60	viability	GATCTGGAGTCGCTAATACAGG	PLEKHH2	ENSG00000152527	-0.13897113533213024	[249,232]	[103,258]	-1	hSpCas9	negative selection	4678982
43697201	43697223	2	+	27760321	HL60	viability	CTACACTAAAGCTTTCGGAAGG	PLEKHH2	ENSG00000152527	0.22735796709584577	[509,413]	[339,544]	2	hSpCas9	negative selection	4678983
43700305	43700327	2	+	27760321	HL60	viability	AAGTGTAGCACTAGCCAAAAGG	PLEKHH2	ENSG00000152527	0.19728483812877506	[114,92]	[125,65]	2	hSpCas9	negative selection	4678984
43700393	43700415	2	+	27760321	HL60	viability	ATACGACCACTGAGACCTCAGG	PLEKHH2	ENSG00000152527	0.5957878079646192	[437,347]	[455,509]	7	hSpCas9	negative selection	4678985
43707528	43707550	2	-	27760321	HL60	viability	TCACCTCGTTTCATGGCTCTGG	PLEKHH2	ENSG00000152527	0.48179003202450676	[2042,1850]	[2180,2259]	6	hSpCas9	negative selection	4678986
43692595	43692617	2	+	27760321	HT1080	viability	GATCTGGAGTCGCTAATACAGG	PLEKHH2	ENSG00000152527	0.6548817350806747	[232,181]	[143,114]	3	hSpCas9	negative selection	4762445
43697201	43697223	2	+	27760321	HT1080	viability	CTACACTAAAGCTTTCGGAAGG	PLEKHH2	ENSG00000152527	0.9355902421224431	[413,322]	[412,135]	5	hSpCas9	negative selection	4762446
43700305	43700327	2	+	27760321	HT1080	viability	AAGTGTAGCACTAGCCAAAAGG	PLEKHH2	ENSG00000152527	1.460171233554429	[92,72]	[48,136]	7	hSpCas9	negative selection	4762447
43700393	43700415	2	+	27760321	HT1080	viability	ATACGACCACTGAGACCTCAGG	PLEKHH2	ENSG00000152527	0.6892215837894602	[347,271]	[159,241]	3	hSpCas9	negative selection	4762448
43707528	43707550	2	-	27760321	HT1080	viability	TCACCTCGTTTCATGGCTCTGG	PLEKHH2	ENSG00000152527	1.3068436332891897	[1850,1444]	[1407,1860]	7	hSpCas9	negative selection	4762449
43692595	43692617	2	+	27760321	HT29	viability after 7 days	GATCTGGAGTCGCTAATACAGG	PLEKHH2	ENSG00000152527	-0.40303270155851345	[232,181]	[179,190,229]	-5	hSpCas9	negative selection	4845908
43697201	43697223	2	+	27760321	HT29	viability after 7 days	CTACACTAAAGCTTTCGGAAGG	PLEKHH2	ENSG00000152527	0.044868291102199385	[413,322]	[405,567,479]	0	hSpCas9	negative selection	4845909
43700305	43700327	2	+	27760321	HT29	viability after 7 days	AAGTGTAGCACTAGCCAAAAGG	PLEKHH2	ENSG00000152527	1.3941715574833142	[92,72]	[263,294,279]	9	hSpCas9	negative selection	4845910
43700393	43700415	2	+	27760321	HT29	viability after 7 days	ATACGACCACTGAGACCTCAGG	PLEKHH2	ENSG00000152527	0.021481400990669003	[347,271]	[563,333,339]	0	hSpCas9	negative selection	4845911
43707528	43707550	2	-	27760321	HT29	viability after 7 days	TCACCTCGTTTCATGGCTCTGG	PLEKHH2	ENSG00000152527	0.11462728305389591	[1850,1444]	[2367,2432,2094]	1	hSpCas9	negative selection	4845912
43692595	43692617	2	+	27760321	HT29	viability after 25 days	GATCTGGAGTCGCTAATACAGG	PLEKHH2	ENSG00000152527	-0.5787045689898186	[232,181]	[129,110,245]	-5	hSpCas9	negative selection	4929371
43697201	43697223	2	+	27760321	HT29	viability after 25 days	CTACACTAAAGCTTTCGGAAGG	PLEKHH2	ENSG00000152527	-0.03465739397618993	[413,322]	[287,450,511]	0	hSpCas9	negative selection	4929372
43700305	43700327	2	+	27760321	HT29	viability after 25 days	AAGTGTAGCACTAGCCAAAAGG	PLEKHH2	ENSG00000152527	1.0294115333480764	[92,72]	[203,191,182]	9	hSpCas9	negative selection	4929373
43700393	43700415	2	+	27760321	HT29	viability after 25 days	ATACGACCACTGAGACCTCAGG	PLEKHH2	ENSG00000152527	0.8301752079079461	[347,271]	[524,545,846]	8	hSpCas9	negative selection	4929374
43707528	43707550	2	-	27760321	HT29	viability after 25 days	TCACCTCGTTTCATGGCTCTGG	PLEKHH2	ENSG00000152527	0.36868771451086113	[1850,1444]	[2165,2869,2253]	4	hSpCas9	negative selection	4929375
43692595	43692617	2	+	27760321	HT29	viability after 22 days	GATCTGGAGTCGCTAATACAGG	PLEKHH2	ENSG00000152527	-0.33785152781098027	[232,181]	[213,139,214]	-3	hSpCas9	negative selection	5012834
43697201	43697223	2	+	27760321	HT29	viability after 22 days	CTACACTAAAGCTTTCGGAAGG	PLEKHH2	ENSG00000152527	-0.5833416972316758	[413,322]	[156,349,349]	-5	hSpCas9	negative selection	5012835
43700305	43700327	2	+	27760321	HT29	viability after 22 days	AAGTGTAGCACTAGCCAAAAGG	PLEKHH2	ENSG00000152527	1.0161225571104098	[92,72]	[227,207,144]	9	hSpCas9	negative selection	5012836
43700393	43700415	2	+	27760321	HT29	viability after 22 days	ATACGACCACTGAGACCTCAGG	PLEKHH2	ENSG00000152527	0.7503439913109895	[347,271]	[765,466,570]	8	hSpCas9	negative selection	5012837
43707528	43707550	2	-	27760321	HT29	viability after 22 days	TCACCTCGTTTCATGGCTCTGG	PLEKHH2	ENSG00000152527	0.30736388728129294	[1850,1444]	[1757,2538,2795]	3	hSpCas9	negative selection	5012838
43692595	43692617	2	+	27760321	HT29	viability after 19 days	GATCTGGAGTCGCTAATACAGG	PLEKHH2	ENSG00000152527	-0.6617188583982404	[232,181]	[139,214,95]	-5	hSpCas9	negative selection	5096297
43697201	43697223	2	+	27760321	HT29	viability after 19 days	CTACACTAAAGCTTTCGGAAGG	PLEKHH2	ENSG00000152527	-0.03331185146923294	[413,322]	[337,438,448]	0	hSpCas9	negative selection	5096298
43700305	43700327	2	+	27760321	HT29	viability after 19 days	AAGTGTAGCACTAGCCAAAAGG	PLEKHH2	ENSG00000152527	1.2808779949838185	[92,72]	[287,177,231]	9	hSpCas9	negative selection	5096299
43700393	43700415	2	+	27760321	HT29	viability after 19 days	ATACGACCACTGAGACCTCAGG	PLEKHH2	ENSG00000152527	0.51732076135802	[347,271]	[523,602,400]	5	hSpCas9	negative selection	5096300
43707528	43707550	2	-	27760321	HT29	viability after 19 days	TCACCTCGTTTCATGGCTCTGG	PLEKHH2	ENSG00000152527	0.6801881668302956	[1850,1444]	[2487,2727,3757]	7	hSpCas9	negative selection	5096301
43692595	43692617	2	+	27760321	HT29	viability after 16 days	GATCTGGAGTCGCTAATACAGG	PLEKHH2	ENSG00000152527	-0.7942494554556664	[232,181]	[115,168,113]	-6	hSpCas9	negative selection	5179760
43697201	43697223	2	+	27760321	HT29	viability after 16 days	CTACACTAAAGCTTTCGGAAGG	PLEKHH2	ENSG00000152527	-0.08668001986003644	[413,322]	[170,353,619]	-1	hSpCas9	negative selection	5179761
43700305	43700327	2	+	27760321	HT29	viability after 16 days	AAGTGTAGCACTAGCCAAAAGG	PLEKHH2	ENSG00000152527	1.1844812437322625	[92,72]	[301,93,248]	9	hSpCas9	negative selection	5179762
43700393	43700415	2	+	27760321	HT29	viability after 16 days	ATACGACCACTGAGACCTCAGG	PLEKHH2	ENSG00000152527	0.5722586466723368	[347,271]	[772,339,462]	6	hSpCas9	negative selection	5179763
43707528	43707550	2	-	27760321	HT29	viability after 16 days	TCACCTCGTTTCATGGCTCTGG	PLEKHH2	ENSG00000152527	0.10792021570057342	[1850,1444]	[2217,1856,1910]	1	hSpCas9	negative selection	5179764
43692595	43692617	2	+	27760321	HT29	viability after 13 days	GATCTGGAGTCGCTAATACAGG	PLEKHH2	ENSG00000152527	-0.19744234417331563	[232,181]	[274,201,155]	-2	hSpCas9	negative selection	5263223
43697201	43697223	2	+	27760321	HT29	viability after 13 days	CTACACTAAAGCTTTCGGAAGG	PLEKHH2	ENSG00000152527	-0.005978996558416987	[413,322]	[396,519,363]	0	hSpCas9	negative selection	5263224
43700305	43700327	2	+	27760321	HT29	viability after 13 days	AAGTGTAGCACTAGCCAAAAGG	PLEKHH2	ENSG00000152527	0.5757021310720896	[92,72]	[192,152,87]	7	hSpCas9	negative selection	5263225
43700393	43700415	2	+	27760321	HT29	viability after 13 days	ATACGACCACTGAGACCTCAGG	PLEKHH2	ENSG00000152527	0.5510102984341949	[347,271]	[398,551,623]	7	hSpCas9	negative selection	5263226
43707528	43707550	2	-	27760321	HT29	viability after 13 days	TCACCTCGTTTCATGGCTCTGG	PLEKHH2	ENSG00000152527	0.19637867648900542	[1850,1444]	[1925,2553,2097]	2	hSpCas9	negative selection	5263227
43692595	43692617	2	+	27760321	HT29	viability after 10 days	GATCTGGAGTCGCTAATACAGG	PLEKHH2	ENSG00000152527	-0.87849049354481	[232,181]	[124,212,87]	-7	hSpCas9	negative selection	5346686
43697201	43697223	2	+	27760321	HT29	viability after 10 days	CTACACTAAAGCTTTCGGAAGG	PLEKHH2	ENSG00000152527	0.032605759218997436	[413,322]	[359,665,392]	0	hSpCas9	negative selection	5346687
43700305	43700327	2	+	27760321	HT29	viability after 10 days	AAGTGTAGCACTAGCCAAAAGG	PLEKHH2	ENSG00000152527	0.9855597006333983	[92,72]	[90,280,244]	9	hSpCas9	negative selection	5346688
43700393	43700415	2	+	27760321	HT29	viability after 10 days	ATACGACCACTGAGACCTCAGG	PLEKHH2	ENSG00000152527	0.5780546459172086	[347,271]	[486,628,617]	7	hSpCas9	negative selection	5346689
43707528	43707550	2	-	27760321	HT29	viability after 10 days	TCACCTCGTTTCATGGCTCTGG	PLEKHH2	ENSG00000152527	0.3093950258297409	[1850,1444]	[2696,2743,2220]	4	hSpCas9	negative selection	5346690
43692595	43692617	2	+	27760321	MOLM13	viability	GATCTGGAGTCGCTAATACAGG	PLEKHH2	ENSG00000152527	0.7348392056835387	[249,232]	[80,350]	5	hSpCas9	negative selection	5430149
43697201	43697223	2	+	27760321	MOLM13	viability	CTACACTAAAGCTTTCGGAAGG	PLEKHH2	ENSG00000152527	0.679293695579504	[509,413]	[223,577]	5	hSpCas9	negative selection	5430150
43700305	43700327	2	+	27760321	MOLM13	viability	AAGTGTAGCACTAGCCAAAAGG	PLEKHH2	ENSG00000152527	-2.5834256022029054	[114,92]	[19,0]	-8	hSpCas9	negative selection	5430151
43700393	43700415	2	+	27760321	MOLM13	viability	ATACGACCACTGAGACCTCAGG	PLEKHH2	ENSG00000152527	-0.13208606950867435	[437,347]	[293,121]	-1	hSpCas9	negative selection	5430152
43707528	43707550	2	-	27760321	MOLM13	viability	TCACCTCGTTTCATGGCTCTGG	PLEKHH2	ENSG00000152527	0.5480474803853035	[2042,1850]	[1814,1425]	4	hSpCas9	negative selection	5430153
43676329	43676352	2	+	27661255	K562	viability	GGCGTTAGGACAGTGTGCCAGGG	PLEKHH2	ENSG00000152527	-0.023403280150503913	[824,868]	[724,613]	-1	dCas9-KRAB	negative selection	5490660
43676336	43676359	2	+	27661255	K562	viability	GGACAGTGTGCCAGGGTCAAAGG	PLEKHH2	ENSG00000152527	-0.02935268979491734	[877,1157]	[821,767]	-1	dCas9-KRAB	negative selection	5490661
43676358	43676381	2	+	27661255	K562	viability	GCAGCCTGGGACCGGGTCCTGGG	PLEKHH2	ENSG00000152527	0.2804739279112809	[846,962]	[983,783]	8	dCas9-KRAB	negative selection	5490662
43676389	43676412	2	-	27661255	K562	viability	GCGCAGCCGCCAGCTCCGGAAGG	PLEKHH2	ENSG00000152527	0.32735189884664173	[235,212]	[212,235]	9	dCas9-KRAB	negative selection	5490663
43676413	43676436	2	-	27661255	K562	viability	GCAGCTAGAGTGGCCCAACCGGG	PLEKHH2	ENSG00000152527	-0.0309021531529714	[772,948]	[721,626]	-1	dCas9-KRAB	negative selection	5490664
43676423	43676446	2	-	27661255	K562	viability	GCGACCTCCCGCAGCTAGAGTGG	PLEKHH2	ENSG00000152527	-0.15112600211397542	[919,777]	[685,549]	-5	dCas9-KRAB	negative selection	5490665
43637296	43637319	2	+	27661255	K562	viability	GGCTGAGAGTCCGGGGATCCCGG	PLEKHH2	ENSG00000152527	-0.16741046663836284	[746,698]	[590,449]	-5	dCas9-KRAB	negative selection	5502558
43637332	43637355	2	-	27661255	K562	viability	GGCCGCAGCGCCCGATGTCCCGG	PLEKHH2	ENSG00000152527	0.1086692595710132	[997,1049]	[939,830]	4	dCas9-KRAB	negative selection	5502559
43644701	43644724	2	-	27260156	BXPC3	viability	CATCGTTCCTTCCAATCTACTGG	PLEKHH2	ENSG00000152527	0.17436704039402767	[486]	[507,582,547,673]	4	hSpCas9	negative selection	5563237
43644712	43644735	2	+	27260156	BXPC3	viability	GAAGGAACGATGTGTAGCTCTGG	PLEKHH2	ENSG00000152527	-0.2873627843998433	[478]	[424,357,362,504]	-6	hSpCas9	negative selection	5563238
43694471	43694494	2	+	27260156	BXPC3	viability	AAGCAGCTAAGATAAAAGAATGG	PLEKHH2	ENSG00000152527	-0.3306177905312455	[92]	[101,51,96,53]	-6	hSpCas9	negative selection	5563239
43644739	43644762	2	-	27260156	BXPC3	viability	GAACTCTAAATTTCATGAGTTGG	PLEKHH2	ENSG00000152527	0.24378630364051324	[251]	[280,333,328,302]	5	hSpCas9	negative selection	5627489
43644676	43644699	2	+	27260156	BXPC3	viability	GGCAGAGCTTTCTGAGCCAGAGG	PLEKHH2	ENSG00000152527	0.22284508079570453	[137]	[129,186,213,141]	5	hSpCas9	negative selection	5627490
43644701	43644724	2	-	27260156	A673	viability	CATCGTTCCTTCCAATCTACTGG	PLEKHH2	ENSG00000152527	0.19672280573929746	[486]	[659,557,631,840]	5	hSpCas9	negative selection	5684488
43644712	43644735	2	+	27260156	A673	viability	GAAGGAACGATGTGTAGCTCTGG	PLEKHH2	ENSG00000152527	-0.1632618353001438	[478]	[594,586,398,478]	-4	hSpCas9	negative selection	5684489
43694471	43694494	2	+	27260156	A673	viability	AAGCAGCTAAGATAAAAGAATGG	PLEKHH2	ENSG00000152527	-0.1288279577120921	[92]	[68,98,108,128]	-3	hSpCas9	negative selection	5684490
43644739	43644762	2	-	27260156	A673	viability	GAACTCTAAATTTCATGAGTTGG	PLEKHH2	ENSG00000152527	-0.04992037072915001	[251]	[326,384,185,271]	-1	hSpCas9	negative selection	5748740
43644676	43644699	2	+	27260156	A673	viability	GGCAGAGCTTTCTGAGCCAGAGG	PLEKHH2	ENSG00000152527	0.009781895240110972	[137]	[148,174,153,187]	0	hSpCas9	negative selection	5748741
43644701	43644724	2	-	27260156	A375	viability	CATCGTTCCTTCCAATCTACTGG	PLEKHH2	ENSG00000152527	0.46152450866625333	[486]	[949,874,905,452]	6	hSpCas9	negative selection	5805739
43644712	43644735	2	+	27260156	A375	viability	GAAGGAACGATGTGTAGCTCTGG	PLEKHH2	ENSG00000152527	-0.021539562949913865	[478]	[361,695,479,668]	0	hSpCas9	negative selection	5805740
43694471	43694494	2	+	27260156	A375	viability	AAGCAGCTAAGATAAAAGAATGG	PLEKHH2	ENSG00000152527	-0.3810762190727668	[92]	[70,102,152,16]	-5	hSpCas9	negative selection	5805741
43644739	43644762	2	-	27260156	A375	viability	GAACTCTAAATTTCATGAGTTGG	PLEKHH2	ENSG00000152527	0.44092565466904776	[251]	[592,456,460,127]	6	hSpCas9	negative selection	5869991
43644676	43644699	2	+	27260156	A375	viability	GGCAGAGCTTTCTGAGCCAGAGG	PLEKHH2	ENSG00000152527	0.14478243142363523	[137]	[147,282,223,82]	2	hSpCas9	negative selection	5869992
43644701	43644724	2	-	27260156	COLO741	viability	CATCGTTCCTTCCAATCTACTGG	PLEKHH2	ENSG00000152527	0.1069166782171493	[486]	[800,650,574]	2	hSpCas9	negative selection	5926990
43644712	43644735	2	+	27260156	COLO741	viability	GAAGGAACGATGTGTAGCTCTGG	PLEKHH2	ENSG00000152527	0.028610325863542906	[478]	[710,506,657]	0	hSpCas9	negative selection	5926991
43694471	43694494	2	+	27260156	COLO741	viability	AAGCAGCTAAGATAAAAGAATGG	PLEKHH2	ENSG00000152527	-1.0882296166279324	[92]	[52,95,20]	-9	hSpCas9	negative selection	5926992
43644739	43644762	2	-	27260156	COLO741	viability	GAACTCTAAATTTCATGAGTTGG	PLEKHH2	ENSG00000152527	-0.02849941212295548	[251]	[381,367,209]	0	hSpCas9	negative selection	5991242
43644676	43644699	2	+	27260156	COLO741	viability	GGCAGAGCTTTCTGAGCCAGAGG	PLEKHH2	ENSG00000152527	0.25927742176360913	[137]	[234,165,231]	5	hSpCas9	negative selection	5991243
43644701	43644724	2	-	27260156	CAL120	viability	CATCGTTCCTTCCAATCTACTGG	PLEKHH2	ENSG00000152527	-0.1783394347245824	[486]	[478,643,475]	-3	hSpCas9	negative selection	6048241
43644712	43644735	2	+	27260156	CAL120	viability	GAAGGAACGATGTGTAGCTCTGG	PLEKHH2	ENSG00000152527	0.06945623331960274	[478]	[497,568,786]	1	hSpCas9	negative selection	6048242
43694471	43694494	2	+	27260156	CAL120	viability	AAGCAGCTAAGATAAAAGAATGG	PLEKHH2	ENSG00000152527	0.6331406598851677	[92]	[67,183,267]	8	hSpCas9	negative selection	6048243
43644739	43644762	2	-	27260156	CAL120	viability	GAACTCTAAATTTCATGAGTTGG	PLEKHH2	ENSG00000152527	0.038646941138295365	[251]	[276,394,287]	0	hSpCas9	negative selection	6112493
43644676	43644699	2	+	27260156	CAL120	viability	GGCAGAGCTTTCTGAGCCAGAGG	PLEKHH2	ENSG00000152527	0.2302941948650883	[137]	[78,146,356]	3	hSpCas9	negative selection	6112494
43644701	43644724	2	-	27260156	CADOES1	viability	CATCGTTCCTTCCAATCTACTGG	PLEKHH2	ENSG00000152527	0.19869962471887465	[486]	[583,422,396,680]	3	hSpCas9	negative selection	6169492
43644712	43644735	2	+	27260156	CADOES1	viability	GAAGGAACGATGTGTAGCTCTGG	PLEKHH2	ENSG00000152527	-0.3611663149835559	[478]	[374,436,240,333]	-6	hSpCas9	negative selection	6169493
43694471	43694494	2	+	27260156	CADOES1	viability	AAGCAGCTAAGATAAAAGAATGG	PLEKHH2	ENSG00000152527	-0.38835949166250483	[92]	[96,53,52,59]	-6	hSpCas9	negative selection	6169494
43644739	43644762	2	-	27260156	CADOES1	viability	GAACTCTAAATTTCATGAGTTGG	PLEKHH2	ENSG00000152527	0.04049268304577658	[251]	[150,215,211,390]	0	hSpCas9	negative selection	6233744
43644676	43644699	2	+	27260156	CADOES1	viability	GGCAGAGCTTTCTGAGCCAGAGG	PLEKHH2	ENSG00000152527	0.18210974614424646	[137]	[140,95,157,188]	3	hSpCas9	negative selection	6233745
43644701	43644724	2	-	27260156	EWS502	viability	CATCGTTCCTTCCAATCTACTGG	PLEKHH2	ENSG00000152527	0.33667188151211547	[486]	[495,673,786,666]	6	hSpCas9	negative selection	6290743
43644712	43644735	2	+	27260156	EWS502	viability	GAAGGAACGATGTGTAGCTCTGG	PLEKHH2	ENSG00000152527	-0.1772349264841446	[478]	[423,406,417,555]	-3	hSpCas9	negative selection	6290744
43694471	43694494	2	+	27260156	EWS502	viability	AAGCAGCTAAGATAAAAGAATGG	PLEKHH2	ENSG00000152527	-0.3995685077367992	[92]	[62,53,143,37]	-6	hSpCas9	negative selection	6290745
43644739	43644762	2	-	27260156	EWS502	viability	GAACTCTAAATTTCATGAGTTGG	PLEKHH2	ENSG00000152527	0.284606816039531	[251]	[348,255,429,260]	5	hSpCas9	negative selection	6354995
43644676	43644699	2	+	27260156	EWS502	viability	GGCAGAGCTTTCTGAGCCAGAGG	PLEKHH2	ENSG00000152527	0.32345553011487604	[137]	[166,163,205,197]	5	hSpCas9	negative selection	6354996
43644701	43644724	2	-	27260156	EW8	viability	CATCGTTCCTTCCAATCTACTGG	PLEKHH2	ENSG00000152527	0.3755525427675141	[486]	[507,471,588,463]	6	hSpCas9	negative selection	6411994
43644712	43644735	2	+	27260156	EW8	viability	GAAGGAACGATGTGTAGCTCTGG	PLEKHH2	ENSG00000152527	0.04756570299570151	[478]	[328,334,406,522]	0	hSpCas9	negative selection	6411995
43694471	43694494	2	+	27260156	EW8	viability	AAGCAGCTAAGATAAAAGAATGG	PLEKHH2	ENSG00000152527	-1.0601529624162556	[92]	[24,47,43,24]	-9	hSpCas9	negative selection	6411996
43644739	43644762	2	-	27260156	EW8	viability	GAACTCTAAATTTCATGAGTTGG	PLEKHH2	ENSG00000152527	0.3851482951009694	[251]	[246,247,156,429]	7	hSpCas9	negative selection	6476246
43644676	43644699	2	+	27260156	EW8	viability	GGCAGAGCTTTCTGAGCCAGAGG	PLEKHH2	ENSG00000152527	-1.0711529132532496	[137]	[109,26,28,56]	-9	hSpCas9	negative selection	6476247
43644701	43644724	2	-	27260156	CORL105	viability	CATCGTTCCTTCCAATCTACTGG	PLEKHH2	ENSG00000152527	0.2215183314855238	[486]	[594,630,829,626]	4	hSpCas9	negative selection	6533245
43644712	43644735	2	+	27260156	CORL105	viability	GAAGGAACGATGTGTAGCTCTGG	PLEKHH2	ENSG00000152527	-0.15460325583679616	[478]	[472,464,532,547]	-3	hSpCas9	negative selection	6533246
43694471	43694494	2	+	27260156	CORL105	viability	AAGCAGCTAAGATAAAAGAATGG	PLEKHH2	ENSG00000152527	-0.5578388359068116	[92]	[80,71,41,95]	-7	hSpCas9	negative selection	6533247
43644739	43644762	2	-	27260156	CORL105	viability	GAACTCTAAATTTCATGAGTTGG	PLEKHH2	ENSG00000152527	0.2716683380984757	[251]	[417,318,284,393]	5	hSpCas9	negative selection	6597497
43644676	43644699	2	+	27260156	CORL105	viability	GGCAGAGCTTTCTGAGCCAGAGG	PLEKHH2	ENSG00000152527	0.36897308560071695	[137]	[204,119,247,268]	7	hSpCas9	negative selection	6597498
43644701	43644724	2	-	27260156	HS294T	viability	CATCGTTCCTTCCAATCTACTGG	PLEKHH2	ENSG00000152527	0.6769109091413428	[486]	[484,223,261,199]	8	hSpCas9	negative selection	6654496
43644712	43644735	2	+	27260156	HS294T	viability	GAAGGAACGATGTGTAGCTCTGG	PLEKHH2	ENSG00000152527	-0.7914473119509327	[478]	[108,76,142,97]	-8	hSpCas9	negative selection	6654497
43694471	43694494	2	+	27260156	HS294T	viability	AAGCAGCTAAGATAAAAGAATGG	PLEKHH2	ENSG00000152527	0.4707325503002626	[92]	[59,40,24,76]	6	hSpCas9	negative selection	6654498
43644739	43644762	2	-	27260156	HS294T	viability	GAACTCTAAATTTCATGAGTTGG	PLEKHH2	ENSG00000152527	0.10836362886704465	[251]	[77,155,109,70]	1	hSpCas9	negative selection	6718748
43644676	43644699	2	+	27260156	HS294T	viability	GGCAGAGCTTTCTGAGCCAGAGG	PLEKHH2	ENSG00000152527	-0.756574145202308	[137]	[13,26,40,48]	-8	hSpCas9	negative selection	6718749
43644701	43644724	2	-	27260156	HCC44	viability	CATCGTTCCTTCCAATCTACTGG	PLEKHH2	ENSG00000152527	0.303314531328125	[486]	[702,628,777,630]	5	hSpCas9	negative selection	6775747
43644712	43644735	2	+	27260156	HCC44	viability	GAAGGAACGATGTGTAGCTCTGG	PLEKHH2	ENSG00000152527	-0.24952494687352714	[478]	[445,386,624,400]	-4	hSpCas9	negative selection	6775748
43694471	43694494	2	+	27260156	HCC44	viability	AAGCAGCTAAGATAAAAGAATGG	PLEKHH2	ENSG00000152527	-0.9446129819202169	[92]	[65,16,26,107]	-8	hSpCas9	negative selection	6775749
43644739	43644762	2	-	27260156	HCC44	viability	GAACTCTAAATTTCATGAGTTGG	PLEKHH2	ENSG00000152527	0.27911073330511593	[251]	[245,161,676,368]	4	hSpCas9	negative selection	6839999
43644676	43644699	2	+	27260156	HCC44	viability	GGCAGAGCTTTCTGAGCCAGAGG	PLEKHH2	ENSG00000152527	0.06328368806252271	[137]	[174,113,179,191]	1	hSpCas9	negative selection	6840000
43644701	43644724	2	-	27260156	G402	viability	CATCGTTCCTTCCAATCTACTGG	PLEKHH2	ENSG00000152527	0.5352675341900927	[486]	[725,785,546,1334]	6	hSpCas9	negative selection	6896998
43644712	43644735	2	+	27260156	G402	viability	GAAGGAACGATGTGTAGCTCTGG	PLEKHH2	ENSG00000152527	-0.5562466018320703	[478]	[566,567,433,69]	-6	hSpCas9	negative selection	6896999
43694471	43694494	2	+	27260156	G402	viability	AAGCAGCTAAGATAAAAGAATGG	PLEKHH2	ENSG00000152527	0.28794851692982126	[92]	[30,48,400,55]	3	hSpCas9	negative selection	6897000
43644739	43644762	2	-	27260156	G402	viability	GAACTCTAAATTTCATGAGTTGG	PLEKHH2	ENSG00000152527	0.2148878088367634	[251]	[480,288,416,257]	2	hSpCas9	negative selection	6961250
43644676	43644699	2	+	27260156	G402	viability	GGCAGAGCTTTCTGAGCCAGAGG	PLEKHH2	ENSG00000152527	0.39567462958953303	[137]	[294,257,102,240]	5	hSpCas9	negative selection	6961251
43644701	43644724	2	-	27260156	L33	viability	CATCGTTCCTTCCAATCTACTGG	PLEKHH2	ENSG00000152527	-0.002969823245094698	[486]	[462,193,303,523]	0	hSpCas9	negative selection	7018249
43644712	43644735	2	+	27260156	L33	viability	GAAGGAACGATGTGTAGCTCTGG	PLEKHH2	ENSG00000152527	-0.15446731229446933	[478]	[487,157,297,372]	-4	hSpCas9	negative selection	7018250
43694471	43694494	2	+	27260156	L33	viability	AAGCAGCTAAGATAAAAGAATGG	PLEKHH2	ENSG00000152527	0.24137689688128328	[92]	[96,26,124,78]	5	hSpCas9	negative selection	7018251
43644739	43644762	2	-	27260156	L33	viability	GAACTCTAAATTTCATGAGTTGG	PLEKHH2	ENSG00000152527	-0.49008293374795664	[251]	[110,106,120,154]	-8	hSpCas9	negative selection	7082501
43644676	43644699	2	+	27260156	L33	viability	GGCAGAGCTTTCTGAGCCAGAGG	PLEKHH2	ENSG00000152527	0.26171589990344546	[137]	[139,84,127,111]	5	hSpCas9	negative selection	7082502
43644701	43644724	2	-	27260156	K562	viability	CATCGTTCCTTCCAATCTACTGG	PLEKHH2	ENSG00000152527	0.1559041605614822	[486]	[351,446,578,527]	2	hSpCas9	negative selection	7139500
43644712	43644735	2	+	27260156	K562	viability	GAAGGAACGATGTGTAGCTCTGG	PLEKHH2	ENSG00000152527	-0.5231500641779049	[478]	[281,250,373,273]	-6	hSpCas9	negative selection	7139501
43694471	43694494	2	+	27260156	K562	viability	AAGCAGCTAAGATAAAAGAATGG	PLEKHH2	ENSG00000152527	-0.9338505412394742	[92]	[90,40,34,12]	-8	hSpCas9	negative selection	7139502
43644739	43644762	2	-	27260156	K562	viability	GAACTCTAAATTTCATGAGTTGG	PLEKHH2	ENSG00000152527	0.49541871376054747	[251]	[411,337,327,203]	6	hSpCas9	negative selection	7203752
43644676	43644699	2	+	27260156	K562	viability	GGCAGAGCTTTCTGAGCCAGAGG	PLEKHH2	ENSG00000152527	0.27435342985009115	[137]	[79,59,164,262]	3	hSpCas9	negative selection	7203753
43644701	43644724	2	-	27260156	HT29	viability	CATCGTTCCTTCCAATCTACTGG	PLEKHH2	ENSG00000152527	0.3824437697490718	[486]	[1056,766,742,561]	7	hSpCas9	negative selection	7260751
43644712	43644735	2	+	27260156	HT29	viability	GAAGGAACGATGTGTAGCTCTGG	PLEKHH2	ENSG00000152527	-0.03558486756568956	[478]	[538,579,552,591]	0	hSpCas9	negative selection	7260752
43694471	43694494	2	+	27260156	HT29	viability	AAGCAGCTAAGATAAAAGAATGG	PLEKHH2	ENSG00000152527	0.02716921118787452	[92]	[109,142,156,58]	0	hSpCas9	negative selection	7260753
43644739	43644762	2	-	27260156	HT29	viability	GAACTCTAAATTTCATGAGTTGG	PLEKHH2	ENSG00000152527	0.46271097018968316	[251]	[369,511,543,280]	8	hSpCas9	negative selection	7325003
43644676	43644699	2	+	27260156	HT29	viability	GGCAGAGCTTTCTGAGCCAGAGG	PLEKHH2	ENSG00000152527	0.16604369880587866	[137]	[173,348,131,117]	3	hSpCas9	negative selection	7325004
43644701	43644724	2	-	27260156	MHHES1	viability	CATCGTTCCTTCCAATCTACTGG	PLEKHH2	ENSG00000152527	0.4311512434537632	[486]	[895,821,758,538]	7	hSpCas9	negative selection	7382002
43644712	43644735	2	+	27260156	MHHES1	viability	GAAGGAACGATGTGTAGCTCTGG	PLEKHH2	ENSG00000152527	-0.1304202517049978	[478]	[609,593,417,386]	-2	hSpCas9	negative selection	7382003
43694471	43694494	2	+	27260156	MHHES1	viability	AAGCAGCTAAGATAAAAGAATGG	PLEKHH2	ENSG00000152527	-0.0011296512013085902	[92]	[103,170,75,77]	0	hSpCas9	negative selection	7382004
43644739	43644762	2	-	27260156	MHHES1	viability	GAACTCTAAATTTCATGAGTTGG	PLEKHH2	ENSG00000152527	0.05017946972331211	[251]	[187,268,473,236]	0	hSpCas9	negative selection	7446254
43644676	43644699	2	+	27260156	MHHES1	viability	GGCAGAGCTTTCTGAGCCAGAGG	PLEKHH2	ENSG00000152527	0.20315513531383034	[137]	[173,219,167,157]	4	hSpCas9	negative selection	7446255
43644701	43644724	2	-	27260156	MEWO	viability	CATCGTTCCTTCCAATCTACTGG	PLEKHH2	ENSG00000152527	0.051534243118364215	[486]	[477,386,552]	1	hSpCas9	negative selection	7503253
43644712	43644735	2	+	27260156	MEWO	viability	GAAGGAACGATGTGTAGCTCTGG	PLEKHH2	ENSG00000152527	-0.07200038975063802	[478]	[583,304,420]	-1	hSpCas9	negative selection	7503254
43694471	43694494	2	+	27260156	MEWO	viability	AAGCAGCTAAGATAAAAGAATGG	PLEKHH2	ENSG00000152527	-0.11724284123411444	[92]	[128,96,23]	-3	hSpCas9	negative selection	7503255
43644739	43644762	2	-	27260156	MEWO	viability	GAACTCTAAATTTCATGAGTTGG	PLEKHH2	ENSG00000152527	-0.08333537010912939	[251]	[234,212,221]	-2	hSpCas9	negative selection	7567505
43644676	43644699	2	+	27260156	MEWO	viability	GGCAGAGCTTTCTGAGCCAGAGG	PLEKHH2	ENSG00000152527	0.30142566311131036	[137]	[269,111,116]	6	hSpCas9	negative selection	7567506
43644701	43644724	2	-	27260156	LNCAPCLONEFGC	viability	CATCGTTCCTTCCAATCTACTGG	PLEKHH2	ENSG00000152527	0.017803653081501752	[486]	[337,454,555,454]	0	hSpCas9	negative selection	7624504
43644712	43644735	2	+	27260156	LNCAPCLONEFGC	viability	GAAGGAACGATGTGTAGCTCTGG	PLEKHH2	ENSG00000152527	-0.2461879526151359	[478]	[354,327,319,455]	-4	hSpCas9	negative selection	7624505
43694471	43694494	2	+	27260156	LNCAPCLONEFGC	viability	AAGCAGCTAAGATAAAAGAATGG	PLEKHH2	ENSG00000152527	0.12895204325690734	[92]	[58,102,109,98]	2	hSpCas9	negative selection	7624506
43644739	43644762	2	-	27260156	LNCAPCLONEFGC	viability	GAACTCTAAATTTCATGAGTTGG	PLEKHH2	ENSG00000152527	0.3764670973005808	[251]	[277,350,350,209]	6	hSpCas9	negative selection	7688756
43644676	43644699	2	+	27260156	LNCAPCLONEFGC	viability	GGCAGAGCTTTCTGAGCCAGAGG	PLEKHH2	ENSG00000152527	0.5459558558842139	[137]	[166,169,316,96]	8	hSpCas9	negative selection	7688757
43644701	43644724	2	-	27260156	PANC0327	viability	CATCGTTCCTTCCAATCTACTGG	PLEKHH2	ENSG00000152527	0.24680367983955787	[486]	[559,420,585,501]	3	hSpCas9	negative selection	7745755
43644712	43644735	2	+	27260156	PANC0327	viability	GAAGGAACGATGTGTAGCTCTGG	PLEKHH2	ENSG00000152527	-0.780029951764241	[478]	[326,242,141,285]	-8	hSpCas9	negative selection	7745756
43694471	43694494	2	+	27260156	PANC0327	viability	AAGCAGCTAAGATAAAAGAATGG	PLEKHH2	ENSG00000152527	-0.3555782403493333	[92]	[70,22,16,152]	-5	hSpCas9	negative selection	7745757
43644739	43644762	2	-	27260156	PANC0327	viability	GAACTCTAAATTTCATGAGTTGG	PLEKHH2	ENSG00000152527	0.23342527735409258	[251]	[238,110,210,508]	3	hSpCas9	negative selection	7810007
43644676	43644699	2	+	27260156	PANC0327	viability	GGCAGAGCTTTCTGAGCCAGAGG	PLEKHH2	ENSG00000152527	-0.1451428636830263	[137]	[136,83,115,111]	-2	hSpCas9	negative selection	7810008
43644701	43644724	2	-	27260156	NCIH2009	viability	CATCGTTCCTTCCAATCTACTGG	PLEKHH2	ENSG00000152527	0.21706276669543334	[486]	[838,781,759]	3	hSpCas9	negative selection	7867006
43644712	43644735	2	+	27260156	NCIH2009	viability	GAAGGAACGATGTGTAGCTCTGG	PLEKHH2	ENSG00000152527	-0.7250063445309572	[478]	[616,343,295]	-7	hSpCas9	negative selection	7867007
43694471	43694494	2	+	27260156	NCIH2009	viability	AAGCAGCTAAGATAAAAGAATGG	PLEKHH2	ENSG00000152527	0.751019320878977	[92]	[317,179,177]	9	hSpCas9	negative selection	7867008
43644739	43644762	2	-	27260156	NCIH2009	viability	GAACTCTAAATTTCATGAGTTGG	PLEKHH2	ENSG00000152527	0.12705073736520933	[251]	[461,392,312]	1	hSpCas9	negative selection	7931258
43644676	43644699	2	+	27260156	NCIH2009	viability	GGCAGAGCTTTCTGAGCCAGAGG	PLEKHH2	ENSG00000152527	0.21828915401744897	[137]	[176,123,363]	3	hSpCas9	negative selection	7931259
43644701	43644724	2	-	27260156	NCIH1373	viability	CATCGTTCCTTCCAATCTACTGG	PLEKHH2	ENSG00000152527	0.5369513089582038	[486]	[1047,555,692,247]	5	hSpCas9	negative selection	7988257
43644712	43644735	2	+	27260156	NCIH1373	viability	GAAGGAACGATGTGTAGCTCTGG	PLEKHH2	ENSG00000152527	-1.5292807240419681	[478]	[235,113,196,55]	-9	hSpCas9	negative selection	7988258
43694471	43694494	2	+	27260156	NCIH1373	viability	AAGCAGCTAAGATAAAAGAATGG	PLEKHH2	ENSG00000152527	0.5519923418644033	[92]	[163,3,101,97]	5	hSpCas9	negative selection	7988259
43644739	43644762	2	-	27260156	NCIH1373	viability	GAACTCTAAATTTCATGAGTTGG	PLEKHH2	ENSG00000152527	0.5224695983231384	[251]	[718,319,232,107]	5	hSpCas9	negative selection	8052509
43644676	43644699	2	+	27260156	NCIH1373	viability	GGCAGAGCTTTCTGAGCCAGAGG	PLEKHH2	ENSG00000152527	0.06068943276199956	[137]	[163,241,71,41]	0	hSpCas9	negative selection	8052510
43644701	43644724	2	-	27260156	PATU8902	viability	CATCGTTCCTTCCAATCTACTGG	PLEKHH2	ENSG00000152527	0.29020462556904847	[486]	[1142,745,665,788]	3	hSpCas9	negative selection	8109508
43644712	43644735	2	+	27260156	PATU8902	viability	GAAGGAACGATGTGTAGCTCTGG	PLEKHH2	ENSG00000152527	-0.27331857756370564	[478]	[957,675,157,502]	-3	hSpCas9	negative selection	8109509
43694471	43694494	2	+	27260156	PATU8902	viability	AAGCAGCTAAGATAAAAGAATGG	PLEKHH2	ENSG00000152527	-0.28191016810308156	[92]	[118,29,125,149]	-3	hSpCas9	negative selection	8109510
43644739	43644762	2	-	27260156	PATU8902	viability	GAACTCTAAATTTCATGAGTTGG	PLEKHH2	ENSG00000152527	-0.36850209443728965	[251]	[524,191,181,196]	-4	hSpCas9	negative selection	8173760
43644676	43644699	2	+	27260156	PATU8902	viability	GGCAGAGCTTTCTGAGCCAGAGG	PLEKHH2	ENSG00000152527	0.2674601384769886	[137]	[448,96,22,428]	2	hSpCas9	negative selection	8173761
43644701	43644724	2	-	27260156	PANC1	viability	CATCGTTCCTTCCAATCTACTGG	PLEKHH2	ENSG00000152527	0.6638438490095238	[486]	[501,624,642,835]	9	hSpCas9	negative selection	8230759
43644712	43644735	2	+	27260156	PANC1	viability	GAAGGAACGATGTGTAGCTCTGG	PLEKHH2	ENSG00000152527	-0.04932577159474345	[478]	[387,505,462,270]	-1	hSpCas9	negative selection	8230760
43694471	43694494	2	+	27260156	PANC1	viability	AAGCAGCTAAGATAAAAGAATGG	PLEKHH2	ENSG00000152527	-0.09121903069423087	[92]	[75,151,50,40]	-1	hSpCas9	negative selection	8230761
43644739	43644762	2	-	27260156	PANC1	viability	GAACTCTAAATTTCATGAGTTGG	PLEKHH2	ENSG00000152527	0.1611698051732673	[251]	[231,226,178,310]	2	hSpCas9	negative selection	8295011
43644676	43644699	2	+	27260156	PANC1	viability	GGCAGAGCTTTCTGAGCCAGAGG	PLEKHH2	ENSG00000152527	-0.0715341199705728	[137]	[105,145,70,129]	-1	hSpCas9	negative selection	8295012
43644701	43644724	2	-	27260156	PANC0813	viability	CATCGTTCCTTCCAATCTACTGG	PLEKHH2	ENSG00000152527	0.04006077491017486	[486]	[626,626,377,714]	0	hSpCas9	negative selection	8352010
43644712	43644735	2	+	27260156	PANC0813	viability	GAAGGAACGATGTGTAGCTCTGG	PLEKHH2	ENSG00000152527	-0.39712544599608135	[478]	[556,309,384,465]	-6	hSpCas9	negative selection	8352011
43694471	43694494	2	+	27260156	PANC0813	viability	AAGCAGCTAAGATAAAAGAATGG	PLEKHH2	ENSG00000152527	0.41078147572901536	[92]	[171,56,131,217]	6	hSpCas9	negative selection	8352012
43644739	43644762	2	-	27260156	PANC0813	viability	GAACTCTAAATTTCATGAGTTGG	PLEKHH2	ENSG00000152527	0.23487166749848298	[251]	[394,343,327,330]	4	hSpCas9	negative selection	8416262
43644676	43644699	2	+	27260156	PANC0813	viability	GGCAGAGCTTTCTGAGCCAGAGG	PLEKHH2	ENSG00000152527	0.2922647591255938	[137]	[232,123,290,151]	5	hSpCas9	negative selection	8416263
43644701	43644724	2	-	27260156	RDES	viability	CATCGTTCCTTCCAATCTACTGG	PLEKHH2	ENSG00000152527	0.2550887199279876	[486]	[688,549,669,762]	4	hSpCas9	negative selection	8473261
43644712	43644735	2	+	27260156	RDES	viability	GAAGGAACGATGTGTAGCTCTGG	PLEKHH2	ENSG00000152527	-0.358404555708955	[478]	[324,423,525,462]	-6	hSpCas9	negative selection	8473262
43694471	43694494	2	+	27260156	RDES	viability	AAGCAGCTAAGATAAAAGAATGG	PLEKHH2	ENSG00000152527	-0.18750903533190755	[92]	[66,73,117,127]	-3	hSpCas9	negative selection	8473263
43644739	43644762	2	-	27260156	RDES	viability	GAACTCTAAATTTCATGAGTTGG	PLEKHH2	ENSG00000152527	0.22146137350554462	[251]	[294,281,369,422]	3	hSpCas9	negative selection	8537513
43644676	43644699	2	+	27260156	RDES	viability	GGCAGAGCTTTCTGAGCCAGAGG	PLEKHH2	ENSG00000152527	0.13342229374866466	[137]	[91,160,247,219]	2	hSpCas9	negative selection	8537514
43644701	43644724	2	-	27260156	PC3	viability	CATCGTTCCTTCCAATCTACTGG	PLEKHH2	ENSG00000152527	0.2877643871759114	[486]	[408,737,717,559]	6	hSpCas9	negative selection	8594512
43644712	43644735	2	+	27260156	PC3	viability	GAAGGAACGATGTGTAGCTCTGG	PLEKHH2	ENSG00000152527	-0.07093687380260626	[478]	[250,389,841,543]	-1	hSpCas9	negative selection	8594513
43694471	43694494	2	+	27260156	PC3	viability	AAGCAGCTAAGATAAAAGAATGG	PLEKHH2	ENSG00000152527	-0.4627397168974845	[92]	[59,61,45,87]	-8	hSpCas9	negative selection	8594514
43644739	43644762	2	-	27260156	PC3	viability	GAACTCTAAATTTCATGAGTTGG	PLEKHH2	ENSG00000152527	0.15886219097561916	[251]	[200,236,417,327]	3	hSpCas9	negative selection	8658764
43644676	43644699	2	+	27260156	PC3	viability	GGCAGAGCTTTCTGAGCCAGAGG	PLEKHH2	ENSG00000152527	0.44201700991969006	[137]	[93,272,278,155]	8	hSpCas9	negative selection	8658765
43644701	43644724	2	-	27260156	PATU8988T	viability	CATCGTTCCTTCCAATCTACTGG	PLEKHH2	ENSG00000152527	0.33586723112860944	[486]	[734,521,430,690]	6	hSpCas9	negative selection	8715763
43644712	43644735	2	+	27260156	PATU8988T	viability	GAAGGAACGATGTGTAGCTCTGG	PLEKHH2	ENSG00000152527	-0.141942291853318	[478]	[341,765,337,251]	-2	hSpCas9	negative selection	8715764
43694471	43694494	2	+	27260156	PATU8988T	viability	AAGCAGCTAAGATAAAAGAATGG	PLEKHH2	ENSG00000152527	-0.1351696676816072	[92]	[79,88,57,102]	-2	hSpCas9	negative selection	8715765
43644739	43644762	2	-	27260156	PATU8988T	viability	GAACTCTAAATTTCATGAGTTGG	PLEKHH2	ENSG00000152527	-0.10243899099736797	[251]	[160,236,178,340]	-2	hSpCas9	negative selection	8780015
43644676	43644699	2	+	27260156	PATU8988T	viability	GGCAGAGCTTTCTGAGCCAGAGG	PLEKHH2	ENSG00000152527	0.8324515460489521	[137]	[154,126,367,291]	9	hSpCas9	negative selection	8780016
43644701	43644724	2	-	27260156	T47D	viability	CATCGTTCCTTCCAATCTACTGG	PLEKHH2	ENSG00000152527	0.3116002765043444	[486]	[803,631,668,718]	6	hSpCas9	negative selection	8837014
43644712	43644735	2	+	27260156	T47D	viability	GAAGGAACGATGTGTAGCTCTGG	PLEKHH2	ENSG00000152527	-0.22855655470484104	[478]	[429,463,531,478]	-5	hSpCas9	negative selection	8837015
43694471	43694494	2	+	27260156	T47D	viability	AAGCAGCTAAGATAAAAGAATGG	PLEKHH2	ENSG00000152527	-0.14668265222399368	[92]	[99,95,89,105]	-3	hSpCas9	negative selection	8837016
43644739	43644762	2	-	27260156	T47D	viability	GAACTCTAAATTTCATGAGTTGG	PLEKHH2	ENSG00000152527	0.5174483239148432	[251]	[454,306,454,474]	9	hSpCas9	negative selection	8901266
43644676	43644699	2	+	27260156	T47D	viability	GGCAGAGCTTTCTGAGCCAGAGG	PLEKHH2	ENSG00000152527	0.9079391341572035	[137]	[215,192,186,631]	9	hSpCas9	negative selection	8901267
43644701	43644724	2	-	27260156	SU8686	viability	CATCGTTCCTTCCAATCTACTGG	PLEKHH2	ENSG00000152527	0.18239371012039396	[486]	[378,573,481,808]	3	hSpCas9	negative selection	8958265
43644712	43644735	2	+	27260156	SU8686	viability	GAAGGAACGATGTGTAGCTCTGG	PLEKHH2	ENSG00000152527	-0.17594563513543973	[478]	[446,410,352,471]	-3	hSpCas9	negative selection	8958266
43694471	43694494	2	+	27260156	SU8686	viability	AAGCAGCTAAGATAAAAGAATGG	PLEKHH2	ENSG00000152527	-0.32095605763216817	[92]	[75,61,79,78]	-5	hSpCas9	negative selection	8958267
43644739	43644762	2	-	27260156	SU8686	viability	GAACTCTAAATTTCATGAGTTGG	PLEKHH2	ENSG00000152527	0.28407357737845507	[251]	[290,312,256,361]	5	hSpCas9	negative selection	9022517
43644676	43644699	2	+	27260156	SU8686	viability	GGCAGAGCTTTCTGAGCCAGAGG	PLEKHH2	ENSG00000152527	0.2546841341764765	[137]	[154,131,163,213]	4	hSpCas9	negative selection	9022518
43644701	43644724	2	-	27260156	SKES1	viability	CATCGTTCCTTCCAATCTACTGG	PLEKHH2	ENSG00000152527	0.4387779249871383	[486]	[791,677,649,541]	8	hSpCas9	negative selection	9079516
43644712	43644735	2	+	27260156	SKES1	viability	GAAGGAACGATGTGTAGCTCTGG	PLEKHH2	ENSG00000152527	-0.2099194899487517	[478]	[559,394,353,363]	-4	hSpCas9	negative selection	9079517
43694471	43694494	2	+	27260156	SKES1	viability	AAGCAGCTAAGATAAAAGAATGG	PLEKHH2	ENSG00000152527	0.07539904892597482	[92]	[94,111,102,82]	1	hSpCas9	negative selection	9079518
43644739	43644762	2	-	27260156	SKES1	viability	GAACTCTAAATTTCATGAGTTGG	PLEKHH2	ENSG00000152527	0.21979243691753425	[251]	[412,144,310,296]	5	hSpCas9	negative selection	9143768
43644676	43644699	2	+	27260156	SKES1	viability	GGCAGAGCTTTCTGAGCCAGAGG	PLEKHH2	ENSG00000152527	-0.22506381424144517	[137]	[84,212,97,84]	-5	hSpCas9	negative selection	9143769
43644701	43644724	2	-	27260156	TOV112D	viability	CATCGTTCCTTCCAATCTACTGG	PLEKHH2	ENSG00000152527	0.4286388668660481	[486]	[621,593,493,889]	7	hSpCas9	negative selection	9200767
43644712	43644735	2	+	27260156	TOV112D	viability	GAAGGAACGATGTGTAGCTCTGG	PLEKHH2	ENSG00000152527	0.028142537319197556	[478]	[461,596,460,460]	0	hSpCas9	negative selection	9200768
43694471	43694494	2	+	27260156	TOV112D	viability	AAGCAGCTAAGATAAAAGAATGG	PLEKHH2	ENSG00000152527	-0.09388489823164292	[92]	[43,232,82,22]	-2	hSpCas9	negative selection	9200769
43644739	43644762	2	-	27260156	TOV112D	viability	GAACTCTAAATTTCATGAGTTGG	PLEKHH2	ENSG00000152527	0.18983005286308863	[251]	[413,278,341,128]	3	hSpCas9	negative selection	9265019
43644676	43644699	2	+	27260156	TOV112D	viability	GGCAGAGCTTTCTGAGCCAGAGG	PLEKHH2	ENSG00000152527	0.6240729602288055	[137]	[116,251,262,220]	9	hSpCas9	negative selection	9265020
43644701	43644724	2	-	27260156	TC71	viability	CATCGTTCCTTCCAATCTACTGG	PLEKHH2	ENSG00000152527	0.10249094032191873	[486]	[454,424,710,653]	2	hSpCas9	negative selection	9322018
43644712	43644735	2	+	27260156	TC71	viability	GAAGGAACGATGTGTAGCTCTGG	PLEKHH2	ENSG00000152527	0.08336534488018796	[478]	[646,497,491,537]	2	hSpCas9	negative selection	9322019
43694471	43694494	2	+	27260156	TC71	viability	AAGCAGCTAAGATAAAAGAATGG	PLEKHH2	ENSG00000152527	-0.5923768144322965	[92]	[44,57,74,87]	-9	hSpCas9	negative selection	9322020
43644739	43644762	2	-	27260156	TC71	viability	GAACTCTAAATTTCATGAGTTGG	PLEKHH2	ENSG00000152527	0.3150827563646781	[251]	[279,369,355,338]	7	hSpCas9	negative selection	9386270
43644676	43644699	2	+	27260156	TC71	viability	GGCAGAGCTTTCTGAGCCAGAGG	PLEKHH2	ENSG00000152527	-0.028620947785386264	[137]	[127,161,119,172]	0	hSpCas9	negative selection	9386271
43644701	43644724	2	-	27260156	TC32	viability	CATCGTTCCTTCCAATCTACTGG	PLEKHH2	ENSG00000152527	-0.04211560193106923	[486]	[419,207,653,610]	0	hSpCas9	negative selection	9443269
43644712	43644735	2	+	27260156	TC32	viability	GAAGGAACGATGTGTAGCTCTGG	PLEKHH2	ENSG00000152527	-0.23367555536160484	[478]	[375,308,346,504]	-4	hSpCas9	negative selection	9443270
43694471	43694494	2	+	27260156	TC32	viability	AAGCAGCTAAGATAAAAGAATGG	PLEKHH2	ENSG00000152527	-0.712161222211313	[92]	[44,45,53,69]	-8	hSpCas9	negative selection	9443271
43644739	43644762	2	-	27260156	TC32	viability	GAACTCTAAATTTCATGAGTTGG	PLEKHH2	ENSG00000152527	-0.03080862703561782	[251]	[216,126,399,241]	0	hSpCas9	negative selection	9507521
43644676	43644699	2	+	27260156	TC32	viability	GGCAGAGCTTTCTGAGCCAGAGG	PLEKHH2	ENSG00000152527	0.12481730585721484	[137]	[191,90,136,148]	2	hSpCas9	negative selection	9507522
43697223	43697246	2	-	27869803	HPAFII	viability after 27 days	AGGTCAAACTGCTCAGGCGCTGG	PLEKHH2	ENSG00000152527	0.05311133645956227	[268]	[149,143,NaN]	0	hSpCas9	negative selection	9575059
43700195	43700218	2	-	27869803	HPAFII	viability after 27 days	GGATGCTTTGGCATTAAAGCTGG	PLEKHH2	ENSG00000152527	0.7277926523714258	[212]	[179,189,NaN]	6	hSpCas9	negative selection	9575060
43707474	43707497	2	-	27869803	HPAFII	viability after 27 days	TGACTCTGACGTCCGGGAGCTGG	PLEKHH2	ENSG00000152527	-0.7818294172699413	[175]	[91,21,NaN]	-5	hSpCas9	negative selection	9575061
43710034	43710057	2	-	27869803	HPAFII	viability after 27 days	TCTGTGGAGTAAGCATCAGGAGG	PLEKHH2	ENSG00000152527	-0.9285101342255829	[233]	[44,80,NaN]	-6	hSpCas9	negative selection	9575062
43710266	43710289	2	+	27869803	HPAFII	viability after 27 days	TCAAGTCTTGGAAGCGGCGGTGG	PLEKHH2	ENSG00000152527	0.7781241278640029	[302]	[276,269,NaN]	6	hSpCas9	negative selection	9575063
43726354	43726377	2	-	27869803	HPAFII	viability after 27 days	GGATAACAGACTTCGTCCACTGG	PLEKHH2	ENSG00000152527	-0.5241975917181584	[187]	[107,35,NaN]	-4	hSpCas9	negative selection	9575064
43697223	43697246	2	-	27869803	HPAFII	viability after 15 days	AGGTCAAACTGCTCAGGCGCTGG	PLEKHH2	ENSG00000152527	0.23215392140580032	[268]	[436,278,NaN]	2	hSpCas9	negative selection	9657508
43700195	43700218	2	-	27869803	HPAFII	viability after 15 days	GGATGCTTTGGCATTAAAGCTGG	PLEKHH2	ENSG00000152527	0.8386061834853257	[212]	[528,334,NaN]	8	hSpCas9	negative selection	9657509
43707474	43707497	2	-	27869803	HPAFII	viability after 15 days	TGACTCTGACGTCCGGGAGCTGG	PLEKHH2	ENSG00000152527	-0.8531957619631115	[175]	[174,60,NaN]	-7	hSpCas9	negative selection	9657510
43710034	43710057	2	-	27869803	HPAFII	viability after 15 days	TCTGTGGAGTAAGCATCAGGAGG	PLEKHH2	ENSG00000152527	-0.3329318650054938	[233]	[137,237,NaN]	-4	hSpCas9	negative selection	9657511
43710266	43710289	2	+	27869803	HPAFII	viability after 15 days	TCAAGTCTTGGAAGCGGCGGTGG	PLEKHH2	ENSG00000152527	0.09559745316501883	[302]	[371,332,NaN]	1	hSpCas9	negative selection	9657512
43726354	43726377	2	-	27869803	HPAFII	viability after 15 days	GGATAACAGACTTCGTCCACTGG	PLEKHH2	ENSG00000152527	0.3308739922434065	[187]	[419,150,NaN]	4	hSpCas9	negative selection	9657513
43697223	43697246	2	-	27869803	ASPC1	viability after 36 days	AGGTCAAACTGCTCAGGCGCTGG	PLEKHH2	ENSG00000152527	0.1667435923385343	[767]	[389,66,420]	1	hSpCas9	negative selection	9739957
43700195	43700218	2	-	27869803	ASPC1	viability after 36 days	GGATGCTTTGGCATTAAAGCTGG	PLEKHH2	ENSG00000152527	0.6301947506417918	[431]	[438,96,194]	6	hSpCas9	negative selection	9739958
43707474	43707497	2	-	27869803	ASPC1	viability after 36 days	TGACTCTGACGTCCGGGAGCTGG	PLEKHH2	ENSG00000152527	0.27443204835206747	[255]	[261,68,29]	2	hSpCas9	negative selection	9739959
43710034	43710057	2	-	27869803	ASPC1	viability after 36 days	TCTGTGGAGTAAGCATCAGGAGG	PLEKHH2	ENSG00000152527	0.40086591247298375	[410]	[159,89,286]	4	hSpCas9	negative selection	9739960
43710266	43710289	2	+	27869803	ASPC1	viability after 36 days	TCAAGTCTTGGAAGCGGCGGTGG	PLEKHH2	ENSG00000152527	-0.020501195424692798	[615]	[99,287,227]	0	hSpCas9	negative selection	9739961
43726354	43726377	2	-	27869803	ASPC1	viability after 36 days	GGATAACAGACTTCGTCCACTGG	PLEKHH2	ENSG00000152527	1.440723027467625	[483]	[1153,217,156]	9	hSpCas9	negative selection	9739962
43697223	43697246	2	-	27869803	PATU8988S	viability after 35 days	AGGTCAAACTGCTCAGGCGCTGG	PLEKHH2	ENSG00000152527	0.9815875969733577	[490]	[383,396,NaN]	8	hSpCas9	negative selection	9822406
43700195	43700218	2	-	27869803	PATU8988S	viability after 35 days	GGATGCTTTGGCATTAAAGCTGG	PLEKHH2	ENSG00000152527	-0.26319629889502616	[383]	[69,187,NaN]	-3	hSpCas9	negative selection	9822407
43707474	43707497	2	-	27869803	PATU8988S	viability after 35 days	TGACTCTGACGTCCGGGAGCTGG	PLEKHH2	ENSG00000152527	-0.020431136909367986	[407]	[166,156,NaN]	0	hSpCas9	negative selection	9822408
43710034	43710057	2	-	27869803	PATU8988S	viability after 35 days	TCTGTGGAGTAAGCATCAGGAGG	PLEKHH2	ENSG00000152527	0.4579708183477439	[433]	[282,196,NaN]	5	hSpCas9	negative selection	9822409
43710266	43710289	2	+	27869803	PATU8988S	viability after 35 days	TCAAGTCTTGGAAGCGGCGGTGG	PLEKHH2	ENSG00000152527	0.2663187949610452	[652]	[234,397,NaN]	3	hSpCas9	negative selection	9822410
43726354	43726377	2	-	27869803	PATU8988S	viability after 35 days	GGATAACAGACTTCGTCCACTGG	PLEKHH2	ENSG00000152527	0.17895250019613762	[337]	[200,106,NaN]	2	hSpCas9	negative selection	9822411
43697223	43697246	2	-	27869803	PATU8988S	viability after 31 days	AGGTCAAACTGCTCAGGCGCTGG	PLEKHH2	ENSG00000152527	1.0732614533912646	[490]	[235,635,NaN]	9	hSpCas9	negative selection	9904855
43700195	43700218	2	-	27869803	PATU8988S	viability after 31 days	GGATGCTTTGGCATTAAAGCTGG	PLEKHH2	ENSG00000152527	-0.40359159796262256	[383]	[80,159,NaN]	-4	hSpCas9	negative selection	9904856
43707474	43707497	2	-	27869803	PATU8988S	viability after 31 days	TGACTCTGACGTCCGGGAGCTGG	PLEKHH2	ENSG00000152527	-0.21340741974261418	[407]	[127,155,NaN]	-2	hSpCas9	negative selection	9904857
43710034	43710057	2	-	27869803	PATU8988S	viability after 31 days	TCTGTGGAGTAAGCATCAGGAGG	PLEKHH2	ENSG00000152527	-0.40558708289772294	[433]	[149,105,NaN]	-4	hSpCas9	negative selection	9904858
43710266	43710289	2	+	27869803	PATU8988S	viability after 31 days	TCAAGTCTTGGAAGCGGCGGTGG	PLEKHH2	ENSG00000152527	0.17316262594977888	[652]	[220,385,NaN]	2	hSpCas9	negative selection	9904859
43726354	43726377	2	-	27869803	PATU8988S	viability after 31 days	GGATAACAGACTTCGTCCACTGG	PLEKHH2	ENSG00000152527	0.22893362917708132	[337]	[120,204,NaN]	3	hSpCas9	negative selection	9904860
43697223	43697246	2	-	27869803	HPAFII	viability after 35 days	AGGTCAAACTGCTCAGGCGCTGG	PLEKHH2	ENSG00000152527	0.533806460462773	[268]	[151,247,NaN]	3	hSpCas9	negative selection	9987304
43700195	43700218	2	-	27869803	HPAFII	viability after 35 days	GGATGCTTTGGCATTAAAGCTGG	PLEKHH2	ENSG00000152527	0.43763305694832266	[212]	[114,180,NaN]	3	hSpCas9	negative selection	9987305
43707474	43707497	2	-	27869803	HPAFII	viability after 35 days	TGACTCTGACGTCCGGGAGCTGG	PLEKHH2	ENSG00000152527	-1.7249921707959284	[175]	[49,0,NaN]	-7	hSpCas9	negative selection	9987306
43710034	43710057	2	-	27869803	HPAFII	viability after 35 days	TCTGTGGAGTAAGCATCAGGAGG	PLEKHH2	ENSG00000152527	-0.7113984045026502	[233]	[61,83,NaN]	-4	hSpCas9	negative selection	9987307
43710266	43710289	2	+	27869803	HPAFII	viability after 35 days	TCAAGTCTTGGAAGCGGCGGTGG	PLEKHH2	ENSG00000152527	0.790139633869429	[302]	[181,358,NaN]	5	hSpCas9	negative selection	9987308
43726354	43726377	2	-	27869803	HPAFII	viability after 35 days	GGATAACAGACTTCGTCCACTGG	PLEKHH2	ENSG00000152527	-1.2192662838918835	[187]	[30,51,NaN]	-6	hSpCas9	negative selection	9987309
43697223	43697246	2	-	27869803	HPAFII	viability after 31 days	AGGTCAAACTGCTCAGGCGCTGG	PLEKHH2	ENSG00000152527	0.30659734085646245	[268]	[157,217,NaN]	2	hSpCas9	negative selection	10069753
43700195	43700218	2	-	27869803	HPAFII	viability after 31 days	GGATGCTTTGGCATTAAAGCTGG	PLEKHH2	ENSG00000152527	0.32967698912249876	[212]	[132,168,NaN]	2	hSpCas9	negative selection	10069754
43707474	43707497	2	-	27869803	HPAFII	viability after 31 days	TGACTCTGACGTCCGGGAGCTGG	PLEKHH2	ENSG00000152527	-0.9852990356101806	[175]	[80,15,NaN]	-6	hSpCas9	negative selection	10069755
43710034	43710057	2	-	27869803	HPAFII	viability after 31 days	TCTGTGGAGTAAGCATCAGGAGG	PLEKHH2	ENSG00000152527	-0.4955096558538715	[233]	[62,125,NaN]	-3	hSpCas9	negative selection	10069756
43710266	43710289	2	+	27869803	HPAFII	viability after 31 days	TCAAGTCTTGGAAGCGGCGGTGG	PLEKHH2	ENSG00000152527	0.7195538381594516	[302]	[123,449,NaN]	5	hSpCas9	negative selection	10069757
43726354	43726377	2	-	27869803	HPAFII	viability after 31 days	GGATAACAGACTTCGTCCACTGG	PLEKHH2	ENSG00000152527	-0.8219038918802377	[187]	[74,42,NaN]	-5	hSpCas9	negative selection	10069758
43700585	43700608	2	-	28162770	P31FUJ	viability	CAAGAAGGAAAACGGTGCAGGGG	PLEKHH2	ENSG00000152527	0.3426059895935288	[201]	[300]	4	hSpCas9	negative selection	10212860
43710283	43710306	2	+	28162770	P31FUJ	viability	CGGTGGTTTGTTCTTAAAGGTGG	PLEKHH2	ENSG00000152527	0.4611841900616327	[292]	[473]	5	hSpCas9	negative selection	10212861
43710263	43710286	2	+	28162770	P31FUJ	viability	AAGTCAAGTCTTGGAAGCGGCGG	PLEKHH2	ENSG00000152527	-0.14944645791889882	[268]	[284]	-1	hSpCas9	negative selection	10212862
43729670	43729693	2	+	28162770	P31FUJ	viability	GGAAGCAACAATGTAAACGTTGG	PLEKHH2	ENSG00000152527	0.36810184017579917	[179]	[272]	4	hSpCas9	negative selection	10212863
43743909	43743932	2	-	28162770	P31FUJ	viability	AACGCAAATCCAGACTGCGCTGG	PLEKHH2	ENSG00000152527	1.8067261597722588	[17]	[73]	9	hSpCas9	negative selection	10212864
43758936	43758959	2	-	28162770	P31FUJ	viability	CAGCAGCACTGTGTCCCCGGAGG	PLEKHH2	ENSG00000152527	0.4097391300185127	[482]	[753]	4	hSpCas9	negative selection	10212865
43692642	43692665	2	+	28162770	P31FUJ	viability	GGAATTGCAACTTGAAGAGCAGG	PLEKHH2	ENSG00000152527	-0.5953722837990868	[170]	[132]	-5	hSpCas9	negative selection	10212866
43699823	43699846	2	+	28162770	P31FUJ	viability	GATGAGGAAGACGGGAGCAAAGG	PLEKHH2	ENSG00000152527	-0.12396571237147236	[535]	[577]	-1	hSpCas9	negative selection	10212867
43700339	43700362	2	-	28162770	P31FUJ	viability	ATCCTGTCAGAGCTTAACTGTGG	PLEKHH2	ENSG00000152527	0.635094259578276	[599]	[1094]	7	hSpCas9	negative selection	10212868
43706388	43706411	2	-	28162770	P31FUJ	viability	CAAAGTTGTATACACTGGGGTGG	PLEKHH2	ENSG00000152527	-0.6478397036932226	[107]	[80]	-5	hSpCas9	negative selection	10212869
43700585	43700608	2	-	28162770	TF1	viability	CAAGAAGGAAAACGGTGCAGGGG	PLEKHH2	ENSG00000152527	NaN	[NaN]	[222]	1	hSpCas9	negative selection	10382226
43710283	43710306	2	+	28162770	TF1	viability	CGGTGGTTTGTTCTTAAAGGTGG	PLEKHH2	ENSG00000152527	NaN	[NaN]	[326]	1	hSpCas9	negative selection	10382227
43710263	43710286	2	+	28162770	TF1	viability	AAGTCAAGTCTTGGAAGCGGCGG	PLEKHH2	ENSG00000152527	NaN	[NaN]	[177]	1	hSpCas9	negative selection	10382228
43729670	43729693	2	+	28162770	TF1	viability	GGAAGCAACAATGTAAACGTTGG	PLEKHH2	ENSG00000152527	NaN	[NaN]	[185]	1	hSpCas9	negative selection	10382229
43743909	43743932	2	-	28162770	TF1	viability	AACGCAAATCCAGACTGCGCTGG	PLEKHH2	ENSG00000152527	NaN	[NaN]	[2]	1	hSpCas9	negative selection	10382230
43758936	43758959	2	-	28162770	TF1	viability	CAGCAGCACTGTGTCCCCGGAGG	PLEKHH2	ENSG00000152527	NaN	[NaN]	[419]	1	hSpCas9	negative selection	10382231
43692642	43692665	2	+	28162770	TF1	viability	GGAATTGCAACTTGAAGAGCAGG	PLEKHH2	ENSG00000152527	NaN	[NaN]	[276]	1	hSpCas9	negative selection	10382232
43699823	43699846	2	+	28162770	TF1	viability	GATGAGGAAGACGGGAGCAAAGG	PLEKHH2	ENSG00000152527	NaN	[NaN]	[419]	1	hSpCas9	negative selection	10382233
43700339	43700362	2	-	28162770	TF1	viability	ATCCTGTCAGAGCTTAACTGTGG	PLEKHH2	ENSG00000152527	NaN	[NaN]	[682]	1	hSpCas9	negative selection	10382234
43706388	43706411	2	-	28162770	TF1	viability	CAAAGTTGTATACACTGGGGTGG	PLEKHH2	ENSG00000152527	NaN	[NaN]	[57]	1	hSpCas9	negative selection	10382235
43700585	43700608	2	-	28162770	SKM1	viability	CAAGAAGGAAAACGGTGCAGGGG	PLEKHH2	ENSG00000152527	0.4999263968653569	[61]	[154]	5	hSpCas9	negative selection	10551592
43710283	43710306	2	+	28162770	SKM1	viability	CGGTGGTTTGTTCTTAAAGGTGG	PLEKHH2	ENSG00000152527	0.7370821708735451	[74]	[220]	7	hSpCas9	negative selection	10551593
43710263	43710286	2	+	28162770	SKM1	viability	AAGTCAAGTCTTGGAAGCGGCGG	PLEKHH2	ENSG00000152527	-0.8408607252733216	[76]	[75]	-6	hSpCas9	negative selection	10551594
43729670	43729693	2	+	28162770	SKM1	viability	GGAAGCAACAATGTAAACGTTGG	PLEKHH2	ENSG00000152527	0.9252322315980278	[41]	[140]	8	hSpCas9	negative selection	10551595
43743909	43743932	2	-	28162770	SKM1	viability	AACGCAAATCCAGACTGCGCTGG	PLEKHH2	ENSG00000152527	-1.1845717774067142	[8]	[6]	-7	hSpCas9	negative selection	10551596
43758936	43758959	2	-	28162770	SKM1	viability	CAGCAGCACTGTGTCCCCGGAGG	PLEKHH2	ENSG00000152527	-0.13320338631630957	[133]	[215]	-1	hSpCas9	negative selection	10551597
43692642	43692665	2	+	28162770	SKM1	viability	GGAATTGCAACTTGAAGAGCAGG	PLEKHH2	ENSG00000152527	0.8135868757691187	[27]	[86]	7	hSpCas9	negative selection	10551598
43699823	43699846	2	+	28162770	SKM1	viability	GATGAGGAAGACGGGAGCAAAGG	PLEKHH2	ENSG00000152527	0.5913954428755829	[109]	[292]	6	hSpCas9	negative selection	10551599
43700339	43700362	2	-	28162770	SKM1	viability	ATCCTGTCAGAGCTTAACTGTGG	PLEKHH2	ENSG00000152527	0.5978050454047104	[150]	[403]	6	hSpCas9	negative selection	10551600
43706388	43706411	2	-	28162770	SKM1	viability	CAAAGTTGTATACACTGGGGTGG	PLEKHH2	ENSG00000152527	0.20774564537204676	[23]	[48]	2	hSpCas9	negative selection	10551601
43700585	43700608	2	-	28162770	SKM1	viability	CAAGAAGGAAAACGGTGCAGGGG	PLEKHH2	ENSG00000152527	0.4999263968653569	[61]	[154]	5	hSpCas9	negative selection	10720958
43710283	43710306	2	+	28162770	SKM1	viability	CGGTGGTTTGTTCTTAAAGGTGG	PLEKHH2	ENSG00000152527	0.7370821708735451	[74]	[220]	7	hSpCas9	negative selection	10720959
43710263	43710286	2	+	28162770	SKM1	viability	AAGTCAAGTCTTGGAAGCGGCGG	PLEKHH2	ENSG00000152527	-0.8408607252733216	[76]	[75]	-6	hSpCas9	negative selection	10720960
43729670	43729693	2	+	28162770	SKM1	viability	GGAAGCAACAATGTAAACGTTGG	PLEKHH2	ENSG00000152527	0.9252322315980278	[41]	[140]	8	hSpCas9	negative selection	10720961
43743909	43743932	2	-	28162770	SKM1	viability	AACGCAAATCCAGACTGCGCTGG	PLEKHH2	ENSG00000152527	-1.1845717774067142	[8]	[6]	-7	hSpCas9	negative selection	10720962
43758936	43758959	2	-	28162770	SKM1	viability	CAGCAGCACTGTGTCCCCGGAGG	PLEKHH2	ENSG00000152527	-0.13320338631630957	[133]	[215]	-1	hSpCas9	negative selection	10720963
43692642	43692665	2	+	28162770	SKM1	viability	GGAATTGCAACTTGAAGAGCAGG	PLEKHH2	ENSG00000152527	0.8135868757691187	[27]	[86]	7	hSpCas9	negative selection	10720964
43699823	43699846	2	+	28162770	SKM1	viability	GATGAGGAAGACGGGAGCAAAGG	PLEKHH2	ENSG00000152527	0.5913954428755829	[109]	[292]	6	hSpCas9	negative selection	10720965
43700339	43700362	2	-	28162770	SKM1	viability	ATCCTGTCAGAGCTTAACTGTGG	PLEKHH2	ENSG00000152527	0.5978050454047104	[150]	[403]	6	hSpCas9	negative selection	10720966
43706388	43706411	2	-	28162770	SKM1	viability	CAAAGTTGTATACACTGGGGTGG	PLEKHH2	ENSG00000152527	0.20774564537204676	[23]	[48]	2	hSpCas9	negative selection	10720967
43700585	43700608	2	-	28162770	PL21	viability	CAAGAAGGAAAACGGTGCAGGGG	PLEKHH2	ENSG00000152527	0.7680286018515348	[169]	[125]	6	hSpCas9	negative selection	10890324
43710283	43710306	2	+	28162770	PL21	viability	CGGTGGTTTGTTCTTAAAGGTGG	PLEKHH2	ENSG00000152527	0.5056421614635713	[211]	[130]	4	hSpCas9	negative selection	10890325
43710263	43710286	2	+	28162770	PL21	viability	AAGTCAAGTCTTGGAAGCGGCGG	PLEKHH2	ENSG00000152527	-1.5461037932648967	[207]	[30]	-7	hSpCas9	negative selection	10890326
43729670	43729693	2	+	28162770	PL21	viability	GGAAGCAACAATGTAAACGTTGG	PLEKHH2	ENSG00000152527	0.7988890669405523	[242]	[183]	6	hSpCas9	negative selection	10890327
43743909	43743932	2	-	28162770	PL21	viability	AACGCAAATCCAGACTGCGCTGG	PLEKHH2	ENSG00000152527	1.149513541419352	[28]	[27]	8	hSpCas9	negative selection	10890328
43758936	43758959	2	-	28162770	PL21	viability	CAGCAGCACTGTGTCCCCGGAGG	PLEKHH2	ENSG00000152527	-0.1544770991042168	[490]	[191]	-1	hSpCas9	negative selection	10890329
43692642	43692665	2	+	28162770	PL21	viability	GGAATTGCAACTTGAAGAGCAGG	PLEKHH2	ENSG00000152527	0.1186097289927216	[90]	[42]	1	hSpCas9	negative selection	10890330
43699823	43699846	2	+	28162770	PL21	viability	GATGAGGAAGACGGGAGCAAAGG	PLEKHH2	ENSG00000152527	-0.13958754833895815	[366]	[144]	-1	hSpCas9	negative selection	10890331
43700339	43700362	2	-	28162770	PL21	viability	ATCCTGTCAGAGCTTAACTGTGG	PLEKHH2	ENSG00000152527	0.17405038562065922	[557]	[273]	1	hSpCas9	negative selection	10890332
43706388	43706411	2	-	28162770	PL21	viability	CAAAGTTGTATACACTGGGGTGG	PLEKHH2	ENSG00000152527	0.5871627375985673	[51]	[33]	5	hSpCas9	negative selection	10890333
43700585	43700608	2	-	28162770	P31FUJ	viability	CAAGAAGGAAAACGGTGCAGGGG	PLEKHH2	ENSG00000152527	0.3426059895935288	[201]	[300]	4	hSpCas9	negative selection	11059690
43710283	43710306	2	+	28162770	P31FUJ	viability	CGGTGGTTTGTTCTTAAAGGTGG	PLEKHH2	ENSG00000152527	0.4611841900616327	[292]	[473]	5	hSpCas9	negative selection	11059691
43710263	43710286	2	+	28162770	P31FUJ	viability	AAGTCAAGTCTTGGAAGCGGCGG	PLEKHH2	ENSG00000152527	-0.14944645791889882	[268]	[284]	-1	hSpCas9	negative selection	11059692
43729670	43729693	2	+	28162770	P31FUJ	viability	GGAAGCAACAATGTAAACGTTGG	PLEKHH2	ENSG00000152527	0.36810184017579917	[179]	[272]	4	hSpCas9	negative selection	11059693
43743909	43743932	2	-	28162770	P31FUJ	viability	AACGCAAATCCAGACTGCGCTGG	PLEKHH2	ENSG00000152527	1.8067261597722588	[17]	[73]	9	hSpCas9	negative selection	11059694
43758936	43758959	2	-	28162770	P31FUJ	viability	CAGCAGCACTGTGTCCCCGGAGG	PLEKHH2	ENSG00000152527	0.4097391300185127	[482]	[753]	4	hSpCas9	negative selection	11059695
43692642	43692665	2	+	28162770	P31FUJ	viability	GGAATTGCAACTTGAAGAGCAGG	PLEKHH2	ENSG00000152527	-0.5953722837990868	[170]	[132]	-5	hSpCas9	negative selection	11059696
43699823	43699846	2	+	28162770	P31FUJ	viability	GATGAGGAAGACGGGAGCAAAGG	PLEKHH2	ENSG00000152527	-0.12396571237147236	[535]	[577]	-1	hSpCas9	negative selection	11059697
43700339	43700362	2	-	28162770	P31FUJ	viability	ATCCTGTCAGAGCTTAACTGTGG	PLEKHH2	ENSG00000152527	0.635094259578276	[599]	[1094]	7	hSpCas9	negative selection	11059698
43706388	43706411	2	-	28162770	P31FUJ	viability	CAAAGTTGTATACACTGGGGTGG	PLEKHH2	ENSG00000152527	-0.6478397036932226	[107]	[80]	-5	hSpCas9	negative selection	11059699
43700585	43700608	2	-	28162770	OCIAML5	viability	CAAGAAGGAAAACGGTGCAGGGG	PLEKHH2	ENSG00000152527	-0.47132224913903076	[148]	[193]	-3	hSpCas9	negative selection	11229056
43710283	43710306	2	+	28162770	OCIAML5	viability	CGGTGGTTTGTTCTTAAAGGTGG	PLEKHH2	ENSG00000152527	0.5101124812677715	[204]	[526]	4	hSpCas9	negative selection	11229057
43710263	43710286	2	+	28162770	OCIAML5	viability	AAGTCAAGTCTTGGAAGCGGCGG	PLEKHH2	ENSG00000152527	-0.8210396752433725	[137]	[140]	-5	hSpCas9	negative selection	11229058
43729670	43729693	2	+	28162770	OCIAML5	viability	GGAAGCAACAATGTAAACGTTGG	PLEKHH2	ENSG00000152527	0.4493141466192798	[98]	[243]	4	hSpCas9	negative selection	11229059
43743909	43743932	2	-	28162770	OCIAML5	viability	AACGCAAATCCAGACTGCGCTGG	PLEKHH2	ENSG00000152527	0.1209663815357338	[26]	[52]	1	hSpCas9	negative selection	11229060
43758936	43758959	2	-	28162770	OCIAML5	viability	CAGCAGCACTGTGTCCCCGGAGG	PLEKHH2	ENSG00000152527	0.15830014469426246	[207]	[418]	1	hSpCas9	negative selection	11229061
43692642	43692665	2	+	28162770	OCIAML5	viability	GGAATTGCAACTTGAAGAGCAGG	PLEKHH2	ENSG00000152527	-0.9556892019381544	[100]	[93]	-5	hSpCas9	negative selection	11229062
43699823	43699846	2	+	28162770	OCIAML5	viability	GATGAGGAAGACGGGAGCAAAGG	PLEKHH2	ENSG00000152527	-0.521287558394369	[259]	[326]	-4	hSpCas9	negative selection	11229063
43700339	43700362	2	-	28162770	OCIAML5	viability	ATCCTGTCAGAGCTTAACTGTGG	PLEKHH2	ENSG00000152527	0.3412301799228252	[414]	[948]	3	hSpCas9	negative selection	11229064
43706388	43706411	2	-	28162770	OCIAML5	viability	CAAAGTTGTATACACTGGGGTGG	PLEKHH2	ENSG00000152527	1.4209519235424188	[53]	[260]	9	hSpCas9	negative selection	11229065
43700585	43700608	2	-	28162770	EOL1	viability	CAAGAAGGAAAACGGTGCAGGGG	PLEKHH2	ENSG00000152527	-0.7292238870692731	[364]	[115]	-5	hSpCas9	negative selection	11398422
43710283	43710306	2	+	28162770	EOL1	viability	CGGTGGTTTGTTCTTAAAGGTGG	PLEKHH2	ENSG00000152527	0.0007194520559386519	[331]	[174]	0	hSpCas9	negative selection	11398423
43710263	43710286	2	+	28162770	EOL1	viability	AAGTCAAGTCTTGGAAGCGGCGG	PLEKHH2	ENSG00000152527	0.5252151729975656	[334]	[253]	5	hSpCas9	negative selection	11398424
43729670	43729693	2	+	28162770	EOL1	viability	GGAAGCAACAATGTAAACGTTGG	PLEKHH2	ENSG00000152527	0.6782839466152444	[324]	[273]	6	hSpCas9	negative selection	11398425
43743909	43743932	2	-	28162770	EOL1	viability	AACGCAAATCCAGACTGCGCTGG	PLEKHH2	ENSG00000152527	-1.611505128669675	[28]	[4]	-7	hSpCas9	negative selection	11398426
43758936	43758959	2	-	28162770	EOL1	viability	CAGCAGCACTGTGTCCCCGGAGG	PLEKHH2	ENSG00000152527	-0.12559287247705808	[848]	[409]	-1	hSpCas9	negative selection	11398427
43692642	43692665	2	+	28162770	EOL1	viability	GGAATTGCAACTTGAAGAGCAGG	PLEKHH2	ENSG00000152527	0.0025502835718076433	[179]	[94]	0	hSpCas9	negative selection	11398428
43699823	43699846	2	+	28162770	EOL1	viability	GATGAGGAAGACGGGAGCAAAGG	PLEKHH2	ENSG00000152527	0.4853564105829139	[521]	[384]	4	hSpCas9	negative selection	11398429
43700339	43700362	2	-	28162770	EOL1	viability	ATCCTGTCAGAGCTTAACTGTGG	PLEKHH2	ENSG00000152527	0.4214540956264945	[607]	[428]	4	hSpCas9	negative selection	11398430
43706388	43706411	2	-	28162770	EOL1	viability	CAAAGTTGTATACACTGGGGTGG	PLEKHH2	ENSG00000152527	-0.714862513172998	[80]	[25]	-5	hSpCas9	negative selection	11398431
43700585	43700608	2	-	28162770	MOLM13	viability	CAAGAAGGAAAACGGTGCAGGGG	PLEKHH2	ENSG00000152527	-0.39359075437399327	[257]	[141]	-2	hSpCas9	negative selection	11567788
43710283	43710306	2	+	28162770	MOLM13	viability	CGGTGGTTTGTTCTTAAAGGTGG	PLEKHH2	ENSG00000152527	0.6770168739558144	[358]	[414]	5	hSpCas9	negative selection	11567789
43710263	43710286	2	+	28162770	MOLM13	viability	AAGTCAAGTCTTGGAAGCGGCGG	PLEKHH2	ENSG00000152527	0.5864177704385407	[326]	[354]	4	hSpCas9	negative selection	11567790
43729670	43729693	2	+	28162770	MOLM13	viability	GGAAGCAACAATGTAAACGTTGG	PLEKHH2	ENSG00000152527	0.7098939321349917	[333]	[394]	5	hSpCas9	negative selection	11567791
43743909	43743932	2	-	28162770	MOLM13	viability	AACGCAAATCCAGACTGCGCTGG	PLEKHH2	ENSG00000152527	2.3137184514168183	[36]	[132]	9	hSpCas9	negative selection	11567792
43758936	43758959	2	-	28162770	MOLM13	viability	CAGCAGCACTGTGTCCCCGGAGG	PLEKHH2	ENSG00000152527	0.7953556599733711	[623]	[782]	6	hSpCas9	negative selection	11567793
43692642	43692665	2	+	28162770	MOLM13	viability	GGAATTGCAACTTGAAGAGCAGG	PLEKHH2	ENSG00000152527	-1.1450874953461738	[207]	[67]	-6	hSpCas9	negative selection	11567794
43699823	43699846	2	+	28162770	MOLM13	viability	GATGAGGAAGACGGGAGCAAAGG	PLEKHH2	ENSG00000152527	-0.36080200221358016	[578]	[325]	-2	hSpCas9	negative selection	11567795
43700339	43700362	2	-	28162770	MOLM13	viability	ATCCTGTCAGAGCTTAACTGTGG	PLEKHH2	ENSG00000152527	0.5827533385765817	[723]	[783]	4	hSpCas9	negative selection	11567796
43706388	43706411	2	-	28162770	MOLM13	viability	CAAAGTTGTATACACTGGGGTGG	PLEKHH2	ENSG00000152527	1.579999747866116	[98]	[213]	9	hSpCas9	negative selection	11567797
43700585	43700608	2	-	28162770	HEL	viability	CAAGAAGGAAAACGGTGCAGGGG	PLEKHH2	ENSG00000152527	0.4309001888246501	[226]	[195]	3	hSpCas9	negative selection	11737154
43710283	43710306	2	+	28162770	HEL	viability	CGGTGGTTTGTTCTTAAAGGTGG	PLEKHH2	ENSG00000152527	-0.073117735571751	[293]	[178]	0	hSpCas9	negative selection	11737155
43710263	43710286	2	+	28162770	HEL	viability	AAGTCAAGTCTTGGAAGCGGCGG	PLEKHH2	ENSG00000152527	0.13684790227039945	[283]	[199]	1	hSpCas9	negative selection	11737156
43729670	43729693	2	+	28162770	HEL	viability	GGAAGCAACAATGTAAACGTTGG	PLEKHH2	ENSG00000152527	-0.20186748535381882	[254]	[141]	-1	hSpCas9	negative selection	11737157
43743909	43743932	2	-	28162770	HEL	viability	AACGCAAATCCAGACTGCGCTGG	PLEKHH2	ENSG00000152527	-0.3870085113936952	[48]	[23]	-3	hSpCas9	negative selection	11737158
43758936	43758959	2	-	28162770	HEL	viability	CAGCAGCACTGTGTCCCCGGAGG	PLEKHH2	ENSG00000152527	0.14969882072023988	[569]	[404]	1	hSpCas9	negative selection	11737159
43692642	43692665	2	+	28162770	HEL	viability	GGAATTGCAACTTGAAGAGCAGG	PLEKHH2	ENSG00000152527	-1.509264261444693	[199]	[44]	-7	hSpCas9	negative selection	11737160
43699823	43699846	2	+	28162770	HEL	viability	GATGAGGAAGACGGGAGCAAAGG	PLEKHH2	ENSG00000152527	0.06315952797610414	[534]	[357]	0	hSpCas9	negative selection	11737161
43700339	43700362	2	-	28162770	HEL	viability	ATCCTGTCAGAGCTTAACTGTGG	PLEKHH2	ENSG00000152527	0.008256195435401903	[651]	[419]	0	hSpCas9	negative selection	11737162
43706388	43706411	2	-	28162770	HEL	viability	CAAAGTTGTATACACTGGGGTGG	PLEKHH2	ENSG00000152527	0.14678133733794585	[54]	[38]	1	hSpCas9	negative selection	11737163
43700585	43700608	2	-	28162770	MV411	viability	CAAGAAGGAAAACGGTGCAGGGG	PLEKHH2	ENSG00000152527	-0.6701002890252516	[186]	[98]	-5	hSpCas9	negative selection	11906520
43710283	43710306	2	+	28162770	MV411	viability	CGGTGGTTTGTTCTTAAAGGTGG	PLEKHH2	ENSG00000152527	1.4844767480836247	[181]	[428]	9	hSpCas9	negative selection	11906521
43710263	43710286	2	+	28162770	MV411	viability	AAGTCAAGTCTTGGAAGCGGCGG	PLEKHH2	ENSG00000152527	-0.26223682263414394	[251]	[176]	-2	hSpCas9	negative selection	11906522
43729670	43729693	2	+	28162770	MV411	viability	GGAAGCAACAATGTAAACGTTGG	PLEKHH2	ENSG00000152527	-0.45465758353637853	[217]	[133]	-3	hSpCas9	negative selection	11906523
43743909	43743932	2	-	28162770	MV411	viability	AACGCAAATCCAGACTGCGCTGG	PLEKHH2	ENSG00000152527	0.24743755078277552	[26]	[26]	2	hSpCas9	negative selection	11906524
43758936	43758959	2	-	28162770	MV411	viability	CAGCAGCACTGTGTCCCCGGAGG	PLEKHH2	ENSG00000152527	0.24040000004284123	[410]	[408]	2	hSpCas9	negative selection	11906525
43692642	43692665	2	+	28162770	MV411	viability	GGAATTGCAACTTGAAGAGCAGG	PLEKHH2	ENSG00000152527	-0.14250896753323805	[113]	[86]	-1	hSpCas9	negative selection	11906526
43699823	43699846	2	+	28162770	MV411	viability	GATGAGGAAGACGGGAGCAAAGG	PLEKHH2	ENSG00000152527	0.07751254934046292	[368]	[327]	0	hSpCas9	negative selection	11906527
43700339	43700362	2	-	28162770	MV411	viability	ATCCTGTCAGAGCTTAACTGTGG	PLEKHH2	ENSG00000152527	0.2971334529366465	[427]	[442]	2	hSpCas9	negative selection	11906528
43706388	43706411	2	-	28162770	MV411	viability	CAAAGTTGTATACACTGGGGTGG	PLEKHH2	ENSG00000152527	-0.7329336424682922	[72]	[36]	-5	hSpCas9	negative selection	11906529
43700585	43700608	2	-	28162770	MONOMAC1	viability	CAAGAAGGAAAACGGTGCAGGGG	PLEKHH2	ENSG00000152527	0.9677079152770786	[123]	[277]	8	hSpCas9	negative selection	12075886
43710283	43710306	2	+	28162770	MONOMAC1	viability	CGGTGGTTTGTTCTTAAAGGTGG	PLEKHH2	ENSG00000152527	-0.025924930666799184	[134]	[151]	0	hSpCas9	negative selection	12075887
43710263	43710286	2	+	28162770	MONOMAC1	viability	AAGTCAAGTCTTGGAAGCGGCGG	PLEKHH2	ENSG00000152527	-1.4164819843456649	[162]	[69]	-8	hSpCas9	negative selection	12075888
43729670	43729693	2	+	28162770	MONOMAC1	viability	GGAAGCAACAATGTAAACGTTGG	PLEKHH2	ENSG00000152527	0.06382972209152996	[110]	[132]	0	hSpCas9	negative selection	12075889
43743909	43743932	2	-	28162770	MONOMAC1	viability	AACGCAAATCCAGACTGCGCTGG	PLEKHH2	ENSG00000152527	-0.5840599701688012	[16]	[12]	-5	hSpCas9	negative selection	12075890
43758936	43758959	2	-	28162770	MONOMAC1	viability	CAGCAGCACTGTGTCCCCGGAGG	PLEKHH2	ENSG00000152527	-0.08026978150641373	[343]	[372]	0	hSpCas9	negative selection	12075891
43692642	43692665	2	+	28162770	MONOMAC1	viability	GGAATTGCAACTTGAAGAGCAGG	PLEKHH2	ENSG00000152527	1.2180006522192899	[47]	[127]	9	hSpCas9	negative selection	12075892
43699823	43699846	2	+	28162770	MONOMAC1	viability	GATGAGGAAGACGGGAGCAAAGG	PLEKHH2	ENSG00000152527	-0.488202688176229	[289]	[236]	-4	hSpCas9	negative selection	12075893
43700339	43700362	2	-	28162770	MONOMAC1	viability	ATCCTGTCAGAGCTTAACTGTGG	PLEKHH2	ENSG00000152527	0.8450544864294791	[303]	[625]	7	hSpCas9	negative selection	12075894
43706388	43706411	2	-	28162770	MONOMAC1	viability	CAAAGTTGTATACACTGGGGTGG	PLEKHH2	ENSG00000152527	-0.7413573632833641	[34]	[23]	-6	hSpCas9	negative selection	12075895
43700585	43700608	2	-	28162770	OCIAML2	viability	CAAGAAGGAAAACGGTGCAGGGG	PLEKHH2	ENSG00000152527	0.7692826951373047	[37]	[358]	7	hSpCas9	negative selection	12245252
43710283	43710306	2	+	28162770	OCIAML2	viability	CGGTGGTTTGTTCTTAAAGGTGG	PLEKHH2	ENSG00000152527	0.9387611108955407	[39]	[424]	8	hSpCas9	negative selection	12245253
43710263	43710286	2	+	28162770	OCIAML2	viability	AAGTCAAGTCTTGGAAGCGGCGG	PLEKHH2	ENSG00000152527	0.04087051353797394	[46]	[267]	0	hSpCas9	negative selection	12245254
43729670	43729693	2	+	28162770	OCIAML2	viability	GGAAGCAACAATGTAAACGTTGG	PLEKHH2	ENSG00000152527	0.3650697225094046	[35]	[256]	3	hSpCas9	negative selection	12245255
43743909	43743932	2	-	28162770	OCIAML2	viability	AACGCAAATCCAGACTGCGCTGG	PLEKHH2	ENSG00000152527	0.11433267547899506	[2]	[17]	1	hSpCas9	negative selection	12245256
43758936	43758959	2	-	28162770	OCIAML2	viability	CAGCAGCACTGTGTCCCCGGAGG	PLEKHH2	ENSG00000152527	0.368089267724778	[77]	[557]	3	hSpCas9	negative selection	12245257
43692642	43692665	2	+	28162770	OCIAML2	viability	GGAATTGCAACTTGAAGAGCAGG	PLEKHH2	ENSG00000152527	1.1072432506926757	[16]	[202]	9	hSpCas9	negative selection	12245258
43699823	43699846	2	+	28162770	OCIAML2	viability	GATGAGGAAGACGGGAGCAAAGG	PLEKHH2	ENSG00000152527	-0.8001979823316553	[70]	[225]	-5	hSpCas9	negative selection	12245259
43700339	43700362	2	-	28162770	OCIAML2	viability	ATCCTGTCAGAGCTTAACTGTGG	PLEKHH2	ENSG00000152527	0.4296881164428712	[87]	[656]	4	hSpCas9	negative selection	12245260
43706388	43706411	2	-	28162770	OCIAML2	viability	CAAAGTTGTATACACTGGGGTGG	PLEKHH2	ENSG00000152527	1.1587267948374482	[7]	[98]	9	hSpCas9	negative selection	12245261
43700585	43700608	2	-	28162770	OCIAML3	viability	CAAGAAGGAAAACGGTGCAGGGG	PLEKHH2	ENSG00000152527	-1.50911874273765	[65]	[69]	-8	hSpCas9	negative selection	12414618
43710283	43710306	2	+	28162770	OCIAML3	viability	CGGTGGTTTGTTCTTAAAGGTGG	PLEKHH2	ENSG00000152527	0.5837794788911197	[60]	[275]	5	hSpCas9	negative selection	12414619
43710263	43710286	2	+	28162770	OCIAML3	viability	AAGTCAAGTCTTGGAAGCGGCGG	PLEKHH2	ENSG00000152527	-0.21926284699335258	[58]	[152]	-2	hSpCas9	negative selection	12414620
43729670	43729693	2	+	28162770	OCIAML3	viability	GGAAGCAACAATGTAAACGTTGG	PLEKHH2	ENSG00000152527	0.2591509713465657	[61]	[223]	2	hSpCas9	negative selection	12414621
43743909	43743932	2	-	28162770	OCIAML3	viability	AACGCAAATCCAGACTGCGCTGG	PLEKHH2	ENSG00000152527	0.034023582288878806	[10]	[33]	0	hSpCas9	negative selection	12414622
43758936	43758959	2	-	28162770	OCIAML3	viability	CAGCAGCACTGTGTCCCCGGAGG	PLEKHH2	ENSG00000152527	-0.3946988321007565	[107]	[247]	-3	hSpCas9	negative selection	12414623
43692642	43692665	2	+	28162770	OCIAML3	viability	GGAATTGCAACTTGAAGAGCAGG	PLEKHH2	ENSG00000152527	0.647750105879216	[36]	[174]	6	hSpCas9	negative selection	12414624
43699823	43699846	2	+	28162770	OCIAML3	viability	GATGAGGAAGACGGGAGCAAAGG	PLEKHH2	ENSG00000152527	-0.03888036914377002	[113]	[334]	0	hSpCas9	negative selection	12414625
43700339	43700362	2	-	28162770	OCIAML3	viability	ATCCTGTCAGAGCTTAACTGTGG	PLEKHH2	ENSG00000152527	0.13810855418064727	[148]	[494]	1	hSpCas9	negative selection	12414626
43706388	43706411	2	-	28162770	OCIAML3	viability	CAAAGTTGTATACACTGGGGTGG	PLEKHH2	ENSG00000152527	0.5592386199715189	[28]	[128]	5	hSpCas9	negative selection	12414627