Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:282809
• Symbol:POC1B
• Description:POC1 centriolar protein B

DataSource: http://genomecrispr.dkfz.de/#!/results/POC1B

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
89497230	89497253	12	+	26472758	Jiyoye	viability	ATGTGGAGAAAACTGCACGCTGG	POC1B	ENSG00000139323	0.5121449411074159	[105]	[113]	4	hSpCas9	negative selection	123231
89466790	89466813	12	-	26472758	Jiyoye	viability	AAGAACACCACATCCCCATGAGG	POC1B	ENSG00000139323	0.17347908677888535	[661]	[562]	1	hSpCas9	negative selection	123232
89491967	89491990	12	+	26472758	Jiyoye	viability	ACAAGGAATACAGGAAGCGCTGG	POC1B	ENSG00000139323	-0.12333933519290638	[155]	[107]	-1	hSpCas9	negative selection	123233
89425327	89425350	12	-	26472758	Jiyoye	viability	GACAAGGGTGAAGAGGCCTGTGG	POC1B	ENSG00000139323	0.901284451775916	[70]	[99]	6	hSpCas9	negative selection	123234
89470482	89470505	12	-	26472758	Jiyoye	viability	TACAAATCAGTTCACAGCGGTGG	POC1B	ENSG00000139323	1.1721165483332647	[142]	[242]	7	hSpCas9	negative selection	123235
89470441	89470464	12	+	26472758	Jiyoye	viability	TGAGATAGTTACCCGAAGGATGG	POC1B	ENSG00000139323	-0.7992754959615531	[59]	[25]	-5	hSpCas9	negative selection	123236
89467630	89467653	12	-	26472758	Jiyoye	viability	GGAGAGCTATTTGCATCAGGAGG	POC1B	ENSG00000139323	0.13537076604434742	[98]	[81]	1	hSpCas9	negative selection	123237
89466813	89466836	12	+	26472758	Jiyoye	viability	GGGTAGATATCAAGAAGATGTGG	POC1B	ENSG00000139323	-0.15672550368745308	[237]	[160]	-1	hSpCas9	negative selection	123238
89492056	89492079	12	+	26472758	Jiyoye	viability	GAAAAGTCTACACTTCGAACTGG	POC1B	ENSG00000139323	-0.10061925869282301	[90]	[63]	0	hSpCas9	negative selection	123239
89471682	89471705	12	+	26472758	Jiyoye	viability	GAAGCTATGCATGTACCACTAGG	POC1B	ENSG00000139323	1.2648548414581626	[164]	[298]	7	hSpCas9	negative selection	123240
89497230	89497253	12	+	26472758	KBM7	viability	ATGTGGAGAAAACTGCACGCTGG	POC1B	ENSG00000139323	1.3185515878564102	[385,298]	[626,193]	9	hSpCas9	negative selection	314349
89466790	89466813	12	-	26472758	KBM7	viability	AAGAACACCACATCCCCATGAGG	POC1B	ENSG00000139323	0.22730236510371515	[2167,2265]	[1455,1025]	2	hSpCas9	negative selection	314350
89491967	89491990	12	+	26472758	KBM7	viability	ACAAGGAATACAGGAAGCGCTGG	POC1B	ENSG00000139323	0.4167861368635081	[477,366]	[254,269]	4	hSpCas9	negative selection	314351
89425327	89425350	12	-	26472758	KBM7	viability	GACAAGGGTGAAGAGGCCTGTGG	POC1B	ENSG00000139323	0.27940836611017583	[512,182]	[162,213]	3	hSpCas9	negative selection	314352
89470482	89470505	12	-	26472758	KBM7	viability	TACAAATCAGTTCACAGCGGTGG	POC1B	ENSG00000139323	1.037084859085449	[991,630]	[910,641]	9	hSpCas9	negative selection	314353
89470441	89470464	12	+	26472758	KBM7	viability	TGAGATAGTTACCCGAAGGATGG	POC1B	ENSG00000139323	-0.6648332673255088	[140,137]	[40,41]	-5	hSpCas9	negative selection	314354
89467630	89467653	12	-	26472758	KBM7	viability	GGAGAGCTATTTGCATCAGGAGG	POC1B	ENSG00000139323	-0.025433368198946038	[275,258]	[127,119]	0	hSpCas9	negative selection	314355
89466813	89466836	12	+	26472758	KBM7	viability	GGGTAGATATCAAGAAGATGTGG	POC1B	ENSG00000139323	0.028215661124075142	[886,743]	[343,429]	0	hSpCas9	negative selection	314356
89492056	89492079	12	+	26472758	KBM7	viability	GAAAAGTCTACACTTCGAACTGG	POC1B	ENSG00000139323	0.2515305129598101	[279,273]	[256,64]	2	hSpCas9	negative selection	314357
89471682	89471705	12	+	26472758	KBM7	viability	GAAGCTATGCATGTACCACTAGG	POC1B	ENSG00000139323	0.3397924939520962	[1272,1498]	[766,896]	3	hSpCas9	negative selection	314358
89497230	89497253	12	+	26472758	Raji	viability	ATGTGGAGAAAACTGCACGCTGG	POC1B	ENSG00000139323	0.36829788933302393	[226]	[67]	3	hSpCas9	negative selection	505467
89466790	89466813	12	-	26472758	Raji	viability	AAGAACACCACATCCCCATGAGG	POC1B	ENSG00000139323	0.4758967541243382	[1291]	[416]	4	hSpCas9	negative selection	505468
89491967	89491990	12	+	26472758	Raji	viability	ACAAGGAATACAGGAAGCGCTGG	POC1B	ENSG00000139323	0.3324500910083731	[153]	[44]	3	hSpCas9	negative selection	505469
89425327	89425350	12	-	26472758	Raji	viability	GACAAGGGTGAAGAGGCCTGTGG	POC1B	ENSG00000139323	0.5758602936139037	[158]	[54]	5	hSpCas9	negative selection	505470
89470482	89470505	12	-	26472758	Raji	viability	TACAAATCAGTTCACAGCGGTGG	POC1B	ENSG00000139323	0.5333921524734464	[392]	[131]	5	hSpCas9	negative selection	505471
89470441	89470464	12	+	26472758	Raji	viability	TGAGATAGTTACCCGAAGGATGG	POC1B	ENSG00000139323	0.4069438172325073	[64]	[19]	4	hSpCas9	negative selection	505472
89467630	89467653	12	-	26472758	Raji	viability	GGAGAGCTATTTGCATCAGGAGG	POC1B	ENSG00000139323	-0.06254146606871303	[143]	[31]	0	hSpCas9	negative selection	505473
89466813	89466836	12	+	26472758	Raji	viability	GGGTAGATATCAAGAAGATGTGG	POC1B	ENSG00000139323	-0.3651042360891441	[554]	[99]	-3	hSpCas9	negative selection	505474
89492056	89492079	12	+	26472758	Raji	viability	GAAAAGTCTACACTTCGAACTGG	POC1B	ENSG00000139323	-0.9575719064671704	[158]	[18]	-6	hSpCas9	negative selection	505475
89471682	89471705	12	+	26472758	Raji	viability	GAAGCTATGCATGTACCACTAGG	POC1B	ENSG00000139323	0.7028245538990203	[502]	[189]	6	hSpCas9	negative selection	505476
89497230	89497253	12	+	26472758	K562	viability	ATGTGGAGAAAACTGCACGCTGG	POC1B	ENSG00000139323	-0.23991140994821814	[262]	[187]	-2	hSpCas9	negative selection	696585
89466790	89466813	12	-	26472758	K562	viability	AAGAACACCACATCCCCATGAGG	POC1B	ENSG00000139323	0.12764452154921235	[1761]	[1624]	0	hSpCas9	negative selection	696586
89491967	89491990	12	+	26472758	K562	viability	ACAAGGAATACAGGAAGCGCTGG	POC1B	ENSG00000139323	0.06502974642631792	[324]	[286]	0	hSpCas9	negative selection	696587
89425327	89425350	12	-	26472758	K562	viability	GACAAGGGTGAAGAGGCCTGTGG	POC1B	ENSG00000139323	0.3468659966372646	[230]	[247]	2	hSpCas9	negative selection	696588
89470482	89470505	12	-	26472758	K562	viability	TACAAATCAGTTCACAGCGGTGG	POC1B	ENSG00000139323	0.04683738332126919	[710]	[619]	0	hSpCas9	negative selection	696589
89470441	89470464	12	+	26472758	K562	viability	TGAGATAGTTACCCGAAGGATGG	POC1B	ENSG00000139323	-0.06276278185172912	[145]	[117]	0	hSpCas9	negative selection	696590
89467630	89467653	12	-	26472758	K562	viability	GGAGAGCTATTTGCATCAGGAGG	POC1B	ENSG00000139323	-0.09227271989265595	[220]	[174]	0	hSpCas9	negative selection	696591
89466813	89466836	12	+	26472758	K562	viability	GGGTAGATATCAAGAAGATGTGG	POC1B	ENSG00000139323	-0.2542439266604888	[875]	[619]	-2	hSpCas9	negative selection	696592
89492056	89492079	12	+	26472758	K562	viability	GAAAAGTCTACACTTCGAACTGG	POC1B	ENSG00000139323	-0.13819729392001934	[175]	[134]	-1	hSpCas9	negative selection	696593
89471682	89471705	12	+	26472758	K562	viability	GAAGCTATGCATGTACCACTAGG	POC1B	ENSG00000139323	-0.006408300271723011	[964]	[810]	0	hSpCas9	negative selection	696594
89425342	89425365	12	-	26627737	DLD1	viability	GGTAGGACTCTGCCAGACAAGGG	POC1B	ENSG00000139323	-0.04001535487181185	[111]	[50,19,30]	0	hSpCas9	negative selection	785790
89467630	89467653	12	-	26627737	DLD1	viability	GGAGAGCTATTTGCATCAGGAGG	POC1B	ENSG00000139323	0.9780164072412505	[186]	[61,118,157]	8	hSpCas9	negative selection	785791
89470441	89470464	12	+	26627737	DLD1	viability	TGAGATAGTTACCCGAAGGATGG	POC1B	ENSG00000139323	0.1461845962812488	[464]	[107,215,160]	1	hSpCas9	negative selection	785792
89471676	89471699	12	-	26627737	DLD1	viability	GGTACATGCATAGCTTCAGCAGG	POC1B	ENSG00000139323	-0.6694526366557643	[100]	[0,7,45]	-6	hSpCas9	negative selection	785793
89491950	89491973	12	-	26627737	DLD1	viability	CCTTGTATCGACATACACACTGG	POC1B	ENSG00000139323	0.16314407922532514	[1354]	[577,487,372]	1	hSpCas9	negative selection	785796
89425342	89425365	12	-	26627737	GBM cells	viability after 5 days	GGTAGGACTCTGCCAGACAAGGG	POC1B	ENSG00000139323	0.3495752838952506	[59]	[34,46]	5	hSpCas9	negative selection	868105
89467630	89467653	12	-	26627737	GBM cells	viability after 5 days	GGAGAGCTATTTGCATCAGGAGG	POC1B	ENSG00000139323	-0.3567410005825109	[116]	[51,45]	-5	hSpCas9	negative selection	868106
89470441	89470464	12	+	26627737	GBM cells	viability after 5 days	TGAGATAGTTACCCGAAGGATGG	POC1B	ENSG00000139323	-0.18081331758504862	[278]	[122,140]	-3	hSpCas9	negative selection	868107
89471676	89471699	12	-	26627737	GBM cells	viability after 5 days	GGTACATGCATAGCTTCAGCAGG	POC1B	ENSG00000139323	-0.05528243550118983	[30]	[7,23]	-1	hSpCas9	negative selection	868108
89491950	89491973	12	-	26627737	GBM cells	viability after 5 days	CCTTGTATCGACATACACACTGG	POC1B	ENSG00000139323	-0.29287627263709104	[481]	[248,172]	-4	hSpCas9	negative selection	868111
89425342	89425365	12	-	26627737	GBM cells	viability after 13 days	GGTAGGACTCTGCCAGACAAGGG	POC1B	ENSG00000139323	0.19694179367949038	[59]	[49,26]	2	hSpCas9	negative selection	950420
89467630	89467653	12	-	26627737	GBM cells	viability after 13 days	GGAGAGCTATTTGCATCAGGAGG	POC1B	ENSG00000139323	-1.7696627478269553	[116]	[11,23]	-9	hSpCas9	negative selection	950421
89470441	89470464	12	+	26627737	GBM cells	viability after 13 days	TGAGATAGTTACCCGAAGGATGG	POC1B	ENSG00000139323	-0.8362510170589235	[278]	[70,95]	-7	hSpCas9	negative selection	950422
89471676	89471699	12	-	26627737	GBM cells	viability after 13 days	GGTACATGCATAGCTTCAGCAGG	POC1B	ENSG00000139323	0.25776908962115197	[30]	[34,7]	3	hSpCas9	negative selection	950423
89491950	89491973	12	-	26627737	GBM cells	viability after 13 days	CCTTGTATCGACATACACACTGG	POC1B	ENSG00000139323	-1.3705805346982807	[481]	[104,97]	-8	hSpCas9	negative selection	950426
89425342	89425365	12	-	26627737	GBM cells	viability after 21 days	GGTAGGACTCTGCCAGACAAGGG	POC1B	ENSG00000139323	-0.11549836874753794	[59]	[27,31]	-1	hSpCas9	negative selection	1032735
89467630	89467653	12	-	26627737	GBM cells	viability after 21 days	GGAGAGCTATTTGCATCAGGAGG	POC1B	ENSG00000139323	-3.0875218216871034	[116]	[7,6]	-9	hSpCas9	negative selection	1032736
89470441	89470464	12	+	26627737	GBM cells	viability after 21 days	TGAGATAGTTACCCGAAGGATGG	POC1B	ENSG00000139323	-1.0672992804902062	[278]	[87,57]	-7	hSpCas9	negative selection	1032737
89471676	89471699	12	-	26627737	GBM cells	viability after 21 days	GGTACATGCATAGCTTCAGCAGG	POC1B	ENSG00000139323	-0.8226647129883915	[30]	[8,9]	-6	hSpCas9	negative selection	1032738
89491950	89491973	12	-	26627737	GBM cells	viability after 21 days	CCTTGTATCGACATACACACTGG	POC1B	ENSG00000139323	-1.759430273327294	[481]	[80,73]	-8	hSpCas9	negative selection	1032741
89425342	89425365	12	-	26627737	RPE1	viability after 9 days	GGTAGGACTCTGCCAGACAAGGG	POC1B	ENSG00000139323	-0.6678913866291778	[326]	[63,64]	-5	hSpCas9	negative selection	1115050
89467630	89467653	12	-	26627737	RPE1	viability after 9 days	GGAGAGCTATTTGCATCAGGAGG	POC1B	ENSG00000139323	-0.29808125832398924	[431]	[109,109]	-2	hSpCas9	negative selection	1115051
89470441	89470464	12	+	26627737	RPE1	viability after 9 days	TGAGATAGTTACCCGAAGGATGG	POC1B	ENSG00000139323	-0.7791272550626503	[1139]	[131,305]	-5	hSpCas9	negative selection	1115052
89471676	89471699	12	-	26627737	RPE1	viability after 9 days	GGTACATGCATAGCTTCAGCAGG	POC1B	ENSG00000139323	-1.7267938352420702	[224]	[36,0]	-8	hSpCas9	negative selection	1115053
89491950	89491973	12	-	26627737	RPE1	viability after 9 days	CCTTGTATCGACATACACACTGG	POC1B	ENSG00000139323	0.7451396454532315	[676]	[232,512]	5	hSpCas9	negative selection	1115056
89425342	89425365	12	-	26627737	RPE1	viability after 12 days	GGTAGGACTCTGCCAGACAAGGG	POC1B	ENSG00000139323	-1.3312898609511816	[326]	[48,19]	-7	hSpCas9	negative selection	1197365
89467630	89467653	12	-	26627737	RPE1	viability after 12 days	GGAGAGCTATTTGCATCAGGAGG	POC1B	ENSG00000139323	-0.7994702617279491	[431]	[72,59]	-5	hSpCas9	negative selection	1197366
89470441	89470464	12	+	26627737	RPE1	viability after 12 days	TGAGATAGTTACCCGAAGGATGG	POC1B	ENSG00000139323	-1.15526900635906	[1139]	[171,100]	-7	hSpCas9	negative selection	1197367
89471676	89471699	12	-	26627737	RPE1	viability after 12 days	GGTACATGCATAGCTTCAGCAGG	POC1B	ENSG00000139323	-2.0725382066833387	[224]	[26,0]	-8	hSpCas9	negative selection	1197368
89491950	89491973	12	-	26627737	RPE1	viability after 12 days	CCTTGTATCGACATACACACTGG	POC1B	ENSG00000139323	0.21556541256923206	[676]	[217,203]	1	hSpCas9	negative selection	1197371
89425342	89425365	12	-	26627737	RPE1	viability after 15 days	GGTAGGACTCTGCCAGACAAGGG	POC1B	ENSG00000139323	-0.5370701151194035	[326]	[105,22]	-3	hSpCas9	negative selection	1279680
89467630	89467653	12	-	26627737	RPE1	viability after 15 days	GGAGAGCTATTTGCATCAGGAGG	POC1B	ENSG00000139323	0.6796214812573407	[431]	[294,99]	4	hSpCas9	negative selection	1279681
89470441	89470464	12	+	26627737	RPE1	viability after 15 days	TGAGATAGTTACCCGAAGGATGG	POC1B	ENSG00000139323	-1.1609245979325031	[1139]	[187,101]	-6	hSpCas9	negative selection	1279682
89471676	89471699	12	-	26627737	RPE1	viability after 15 days	GGTACATGCATAGCTTCAGCAGG	POC1B	ENSG00000139323	-3.691146638019667	[224]	[8,0]	-9	hSpCas9	negative selection	1279683
89491950	89491973	12	-	26627737	RPE1	viability after 15 days	CCTTGTATCGACATACACACTGG	POC1B	ENSG00000139323	-0.4145149922530249	[676]	[48,234]	-3	hSpCas9	negative selection	1279686
89425342	89425365	12	-	26627737	RPE1	viability after 18 days	GGTAGGACTCTGCCAGACAAGGG	POC1B	ENSG00000139323	-1.395451707679295	[326]	[63,0]	-7	hSpCas9	negative selection	1361995
89467630	89467653	12	-	26627737	RPE1	viability after 18 days	GGAGAGCTATTTGCATCAGGAGG	POC1B	ENSG00000139323	-0.5029222103847725	[431]	[60,104]	-3	hSpCas9	negative selection	1361996
89470441	89470464	12	+	26627737	RPE1	viability after 18 days	TGAGATAGTTACCCGAAGGATGG	POC1B	ENSG00000139323	-0.7641333875229227	[1139]	[199,160]	-5	hSpCas9	negative selection	1361997
89471676	89471699	12	-	26627737	RPE1	viability after 18 days	GGTACATGCATAGCTTCAGCAGG	POC1B	ENSG00000139323	-1.7096787068727333	[224]	[34,0]	-8	hSpCas9	negative selection	1361998
89491950	89491973	12	-	26627737	RPE1	viability after 18 days	CCTTGTATCGACATACACACTGG	POC1B	ENSG00000139323	0.1537425480581772	[676]	[122,288]	1	hSpCas9	negative selection	1362001
89425342	89425365	12	-	26627737	HeLa	viability after 8 days	GGTAGGACTCTGCCAGACAAGGG	POC1B	ENSG00000139323	0.21849707610514635	[108]	[5,141,9]	2	hSpCas9	negative selection	1444310
89467630	89467653	12	-	26627737	HeLa	viability after 8 days	GGAGAGCTATTTGCATCAGGAGG	POC1B	ENSG00000139323	-0.6905303039507553	[248]	[58,93,47]	-6	hSpCas9	negative selection	1444311
89470441	89470464	12	+	26627737	HeLa	viability after 8 days	TGAGATAGTTACCCGAAGGATGG	POC1B	ENSG00000139323	0.6915482662062449	[310]	[243,179,235]	6	hSpCas9	negative selection	1444312
89471676	89471699	12	-	26627737	HeLa	viability after 8 days	GGTACATGCATAGCTTCAGCAGG	POC1B	ENSG00000139323	-0.09118977710889009	[97]	[71,27,27]	-1	hSpCas9	negative selection	1444313
89491950	89491973	12	-	26627737	HeLa	viability after 8 days	CCTTGTATCGACATACACACTGG	POC1B	ENSG00000139323	1.7254243895107866	[281]	[501,293,439]	9	hSpCas9	negative selection	1444316
89425342	89425365	12	-	26627737	HeLa	viability after 12 days	GGTAGGACTCTGCCAGACAAGGG	POC1B	ENSG00000139323	0.24790438905914747	[108]	[36,43,79]	2	hSpCas9	negative selection	1526625
89467630	89467653	12	-	26627737	HeLa	viability after 12 days	GGAGAGCTATTTGCATCAGGAGG	POC1B	ENSG00000139323	-0.1964955204954444	[248]	[186,6,86]	-2	hSpCas9	negative selection	1526626
89470441	89470464	12	+	26627737	HeLa	viability after 12 days	TGAGATAGTTACCCGAAGGATGG	POC1B	ENSG00000139323	0.11509878940864027	[310]	[190,92,139]	1	hSpCas9	negative selection	1526627
89471676	89471699	12	-	26627737	HeLa	viability after 12 days	GGTACATGCATAGCTTCAGCAGG	POC1B	ENSG00000139323	-0.6970213203680884	[97]	[76,0,0]	-6	hSpCas9	negative selection	1526628
89491950	89491973	12	-	26627737	HeLa	viability after 12 days	CCTTGTATCGACATACACACTGG	POC1B	ENSG00000139323	2.0990216764255223	[281]	[807,289,430]	9	hSpCas9	negative selection	1526631
89425342	89425365	12	-	26627737	HeLa	viability after 15 days	GGTAGGACTCTGCCAGACAAGGG	POC1B	ENSG00000139323	0.004255045582697292	[108]	[3,85,43]	0	hSpCas9	negative selection	1608940
89467630	89467653	12	-	26627737	HeLa	viability after 15 days	GGAGAGCTATTTGCATCAGGAGG	POC1B	ENSG00000139323	0.04619506955178565	[248]	[72,32,216]	0	hSpCas9	negative selection	1608941
89470441	89470464	12	+	26627737	HeLa	viability after 15 days	TGAGATAGTTACCCGAAGGATGG	POC1B	ENSG00000139323	0.6390918058123395	[310]	[176,214,199]	5	hSpCas9	negative selection	1608942
89471676	89471699	12	-	26627737	HeLa	viability after 15 days	GGTACATGCATAGCTTCAGCAGG	POC1B	ENSG00000139323	-3.1788733461062044	[97]	[0,10,0]	-9	hSpCas9	negative selection	1608943
89491950	89491973	12	-	26627737	HeLa	viability after 15 days	CCTTGTATCGACATACACACTGG	POC1B	ENSG00000139323	1.196180758902442	[281]	[156,412,216]	8	hSpCas9	negative selection	1608946
89425342	89425365	12	-	26627737	HeLa	viability after 18 days	GGTAGGACTCTGCCAGACAAGGG	POC1B	ENSG00000139323	-0.03377202114301148	[108]	[2,67,43]	0	hSpCas9	negative selection	1691255
89467630	89467653	12	-	26627737	HeLa	viability after 18 days	GGAGAGCTATTTGCATCAGGAGG	POC1B	ENSG00000139323	-0.006046933361693596	[248]	[41,26,216]	0	hSpCas9	negative selection	1691256
89470441	89470464	12	+	26627737	HeLa	viability after 18 days	TGAGATAGTTACCCGAAGGATGG	POC1B	ENSG00000139323	0.671151441018935	[310]	[124,180,199]	5	hSpCas9	negative selection	1691257
89471676	89471699	12	-	26627737	HeLa	viability after 18 days	GGTACATGCATAGCTTCAGCAGG	POC1B	ENSG00000139323	-3.427707915968001	[97]	[0,6,0]	-9	hSpCas9	negative selection	1691258
89491950	89491973	12	-	26627737	HeLa	viability after 18 days	CCTTGTATCGACATACACACTGG	POC1B	ENSG00000139323	1.2070750208516334	[281]	[105,345,216]	8	hSpCas9	negative selection	1691261
89425342	89425365	12	-	26627737	HCT116	viability after 6 days	GGTAGGACTCTGCCAGACAAGGG	POC1B	ENSG00000139323	-1.8391642826179684	[132]	[10,2]	-8	hSpCas9	negative selection	1773570
89467630	89467653	12	-	26627737	HCT116	viability after 6 days	GGAGAGCTATTTGCATCAGGAGG	POC1B	ENSG00000139323	-0.9395958178731161	[291]	[21,24]	-5	hSpCas9	negative selection	1773571
89470441	89470464	12	+	26627737	HCT116	viability after 6 days	TGAGATAGTTACCCGAAGGATGG	POC1B	ENSG00000139323	1.0085725851762037	[702]	[115,280]	5	hSpCas9	negative selection	1773572
89471676	89471699	12	-	26627737	HCT116	viability after 6 days	GGTACATGCATAGCTTCAGCAGG	POC1B	ENSG00000139323	0.3232004998273066	[33]	[16,0]	1	hSpCas9	negative selection	1773573
89491950	89491973	12	-	26627737	HCT116	viability after 6 days	CCTTGTATCGACATACACACTGG	POC1B	ENSG00000139323	0.16084715655846082	[1252]	[138,264]	0	hSpCas9	negative selection	1773576
89425342	89425365	12	-	26627737	HCT116	viability after 8 days	GGTAGGACTCTGCCAGACAAGGG	POC1B	ENSG00000139323	0.6507027787790975	[27]	[5,13,51]	6	hSpCas9	negative selection	1855885
89467630	89467653	12	-	26627737	HCT116	viability after 8 days	GGAGAGCTATTTGCATCAGGAGG	POC1B	ENSG00000139323	-0.32634239466747306	[173]	[49,107,70]	-4	hSpCas9	negative selection	1855886
89470441	89470464	12	+	26627737	HCT116	viability after 8 days	TGAGATAGTTACCCGAAGGATGG	POC1B	ENSG00000139323	-0.22600033683068566	[370]	[150,202,169]	-3	hSpCas9	negative selection	1855887
89471676	89471699	12	-	26627737	HCT116	viability after 8 days	GGTACATGCATAGCTTCAGCAGG	POC1B	ENSG00000139323	1.1844092448398782	[32]	[33,60,28]	8	hSpCas9	negative selection	1855888
89491950	89491973	12	-	26627737	HCT116	viability after 8 days	CCTTGTATCGACATACACACTGG	POC1B	ENSG00000139323	-0.3539038093302852	[720]	[345,257,328]	-4	hSpCas9	negative selection	1855891
89425342	89425365	12	-	26627737	HCT116	viability after 9 days	GGTAGGACTCTGCCAGACAAGGG	POC1B	ENSG00000139323	-1.4182092513612612	[132]	[0,22]	-7	hSpCas9	negative selection	1938200
89467630	89467653	12	-	26627737	HCT116	viability after 9 days	GGAGAGCTATTTGCATCAGGAGG	POC1B	ENSG00000139323	-0.12997103480005956	[291]	[44,91]	-1	hSpCas9	negative selection	1938201
89470441	89470464	12	+	26627737	HCT116	viability after 9 days	TGAGATAGTTACCCGAAGGATGG	POC1B	ENSG00000139323	-1.4743244259624484	[702]	[66,67]	-8	hSpCas9	negative selection	1938202
89471676	89471699	12	-	26627737	HCT116	viability after 9 days	GGTACATGCATAGCTTCAGCAGG	POC1B	ENSG00000139323	-1.9656616408237229	[33]	[3,0]	-8	hSpCas9	negative selection	1938203
89491950	89491973	12	-	26627737	HCT116	viability after 9 days	CCTTGTATCGACATACACACTGG	POC1B	ENSG00000139323	-0.7534148797302527	[1252]	[69,299]	-5	hSpCas9	negative selection	1938206
89425342	89425365	12	-	26627737	HCT116	viability after 12 days	GGTAGGACTCTGCCAGACAAGGG	POC1B	ENSG00000139323	1.7830814291067156	[27]	[22,35,94]	9	hSpCas9	negative selection	2020515
89467630	89467653	12	-	26627737	HCT116	viability after 12 days	GGAGAGCTATTTGCATCAGGAGG	POC1B	ENSG00000139323	-0.310369316369133	[173]	[82,97,39]	-3	hSpCas9	negative selection	2020516
89470441	89470464	12	+	26627737	HCT116	viability after 12 days	TGAGATAGTTACCCGAAGGATGG	POC1B	ENSG00000139323	0.0038246034435253096	[370]	[181,209,195]	0	hSpCas9	negative selection	2020517
89471676	89471699	12	-	26627737	HCT116	viability after 12 days	GGTACATGCATAGCTTCAGCAGG	POC1B	ENSG00000139323	1.3625465550668558	[32]	[9,51,74]	9	hSpCas9	negative selection	2020518
89491950	89491973	12	-	26627737	HCT116	viability after 12 days	CCTTGTATCGACATACACACTGG	POC1B	ENSG00000139323	-0.6169814374466592	[720]	[235,240,264]	-6	hSpCas9	negative selection	2020521
89425342	89425365	12	-	26627737	HCT116	viability after 15 days	GGTAGGACTCTGCCAGACAAGGG	POC1B	ENSG00000139323	1.6024299561587525	[27]	[16,25,98]	9	hSpCas9	negative selection	2102830
89467630	89467653	12	-	26627737	HCT116	viability after 15 days	GGAGAGCTATTTGCATCAGGAGG	POC1B	ENSG00000139323	-0.062317548798594524	[173]	[74,64,143]	0	hSpCas9	negative selection	2102831
89470441	89470464	12	+	26627737	HCT116	viability after 15 days	TGAGATAGTTACCCGAAGGATGG	POC1B	ENSG00000139323	-0.3291728104822795	[370]	[143,135,224]	-3	hSpCas9	negative selection	2102832
89471676	89471699	12	-	26627737	HCT116	viability after 15 days	GGTACATGCATAGCTTCAGCAGG	POC1B	ENSG00000139323	0.6247875147851132	[32]	[24,19,41]	6	hSpCas9	negative selection	2102833
89491950	89491973	12	-	26627737	HCT116	viability after 15 days	CCTTGTATCGACATACACACTGG	POC1B	ENSG00000139323	-0.5386138570041841	[720]	[304,383,169]	-5	hSpCas9	negative selection	2102836
89425342	89425365	12	-	26627737	HCT116	viability after 18 days	GGTAGGACTCTGCCAGACAAGGG	POC1B	ENSG00000139323	1.3279421986926345	[27]	[50,17,33]	8	hSpCas9	negative selection	2185145
89467630	89467653	12	-	26627737	HCT116	viability after 18 days	GGAGAGCTATTTGCATCAGGAGG	POC1B	ENSG00000139323	-0.5746626030624538	[173]	[57,33,79]	-5	hSpCas9	negative selection	2185146
89470441	89470464	12	+	26627737	HCT116	viability after 18 days	TGAGATAGTTACCCGAAGGATGG	POC1B	ENSG00000139323	-0.02952689344652204	[370]	[129,118,286]	0	hSpCas9	negative selection	2185147
89471676	89471699	12	-	26627737	HCT116	viability after 18 days	GGTACATGCATAGCTTCAGCAGG	POC1B	ENSG00000139323	2.171059964039113	[32]	[44,78,91]	9	hSpCas9	negative selection	2185148
89491950	89491973	12	-	26627737	HCT116	viability after 18 days	CCTTGTATCGACATACACACTGG	POC1B	ENSG00000139323	-0.28102291726855255	[720]	[205,333,318]	-3	hSpCas9	negative selection	2185151
89482962	89482985	12	+	25494202	A375	resistance to PLX-4720 (puromycin)	TTGCCCAGGCTGGAGTGCAACGG	POC1B	ENSG00000139323	-0.29783996533031276	[705,290]	[109,64]	-1	dCas9-VP64	positive selection	2393677
89504156	89504179	12	+	25494202	A375	resistance to PLX-4720 (puromycin)	GAATAGAAAAGGGGGAAATGTGG	POC1B	ENSG00000139323	-0.5261836086397467	[77,118]	[9,19]	-3	dCas9-VP64	positive selection	2419298
89482962	89482985	12	+	25494202	A375	resistance to PLX-4720 (zeocin)	TTGCCCAGGCTGGAGTGCAACGG	POC1B	ENSG00000139323	-0.2409913144319511	[429,255]	[120,70]	-2	dCas9-VP64	positive selection	2488932
89504156	89504179	12	+	25494202	A375	resistance to PLX-4720 (zeocin)	GAATAGAAAAGGGGGAAATGTGG	POC1B	ENSG00000139323	0.026051413979125304	[91,92]	[41,19]	0	dCas9-VP64	positive selection	2514553
89472153	89472176	12	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	AAGAAAGTGTACTTACCCAACGG	POC1B	ENSG00000139323	0.8580202448260935	[3,3]	[2,7]	9	hSpCas9	positive selection	3012316
89472167	89472190	12	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	ATAACTTCTCAGATTCCGTTGGG	POC1B	ENSG00000139323	-0.28115837717405984	[3,4]	[4,1]	-4	hSpCas9	positive selection	3012317
89491950	89491973	12	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CCTTGTATCGACATACACACTGG	POC1B	ENSG00000139323	-0.4455509717512436	[1,2]	[0,1]	-6	hSpCas9	positive selection	3012318
89470438	89470461	12	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GTGATGAGATAGTTACCCGAAGG	POC1B	ENSG00000139323	0.29437542050583	[3,3]	[4,3]	6	hSpCas9	positive selection	3012319
89472153	89472176	12	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	AAGAAAGTGTACTTACCCAACGG	POC1B	ENSG00000139323	0.023138722152801924	[3,3]	[3,0]	0	hSpCas9	positive selection	3080174
89472167	89472190	12	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	ATAACTTCTCAGATTCCGTTGGG	POC1B	ENSG00000139323	-0.03531238527066628	[3,3]	[2,2]	0	hSpCas9	positive selection	3080175
89491950	89491973	12	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CCTTGTATCGACATACACACTGG	POC1B	ENSG00000139323	0.4072233202801037	[1,1]	[2,0]	7	hSpCas9	positive selection	3080176
89470438	89470461	12	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GTGATGAGATAGTTACCCGAAGG	POC1B	ENSG00000139323	0.19032555662547654	[3,3]	[2,2]	3	hSpCas9	positive selection	3080177
89491950	89491973		+	24336571	A375	resistance to PLX after 7 days	CCAGTGTGTATGTCGATACAAGG	POC1B	ENSG00000139323	0.025449415854776225	[50,45]	[47,49]	1	hSpCas9	positive selection	3136607
89491950	89491973		-	24336571	A375	resistance to PLX after 7 days	CCTTGTATCGACATACACACTGG	POC1B	ENSG00000139323	0.10255736488897993	[27,30]	[31,29]	3	hSpCas9	positive selection	3136608
89472261	89472284		-	24336571	A375	resistance to PLX after 7 days	CTTTCTAGATTTTCACCCGATGG	POC1B	ENSG00000139323	0.10836105263949414	[5,5]	[7,5]	3	hSpCas9	positive selection	3136609
89472245	89472268		+	24336571	A375	resistance to PLX after 7 days	TGACACAATTAGTCTTCCATCGG	POC1B	ENSG00000139323	-0.19808871564552588	[24,29]	[23,22]	-6	hSpCas9	positive selection	3136611
89491950	89491973		+	24336571	A375	resistance to PLX after 14 days	CCAGTGTGTATGTCGATACAAGG	POC1B	ENSG00000139323	0.2809487860221891	[52,45]	[24,30]	3	hSpCas9	positive selection	3194400
89491950	89491973		-	24336571	A375	resistance to PLX after 14 days	CCTTGTATCGACATACACACTGG	POC1B	ENSG00000139323	0.2475152346945948	[26,34]	[18,14]	2	hSpCas9	positive selection	3194401
89472261	89472284		-	24336571	A375	resistance to PLX after 14 days	CTTTCTAGATTTTCACCCGATGG	POC1B	ENSG00000139323	2.4903100193179504	[5,3]	[9,15]	9	hSpCas9	positive selection	3194402
89472245	89472268		+	24336571	A375	resistance to PLX after 14 days	TGACACAATTAGTCTTCCATCGG	POC1B	ENSG00000139323	-0.848010760375213	[20,17]	[5,3]	-8	hSpCas9	positive selection	3194404
89491950	89491973		+	24336571	A375	viability after 7 days	CCAGTGTGTATGTCGATACAAGG	POC1B	ENSG00000139323	0.31174127792178297	[40]	[50,45]	5	hSpCas9	negative selection	3252193
89491950	89491973		-	24336571	A375	viability after 7 days	CCTTGTATCGACATACACACTGG	POC1B	ENSG00000139323	-0.19159137690060968	[34]	[27,30]	-3	hSpCas9	negative selection	3252194
89472261	89472284		-	24336571	A375	viability after 7 days	CTTTCTAGATTTTCACCCGATGG	POC1B	ENSG00000139323	-0.8845403960832571	[12]	[5,5]	-8	hSpCas9	negative selection	3252195
89472245	89472268		+	24336571	A375	viability after 7 days	TGACACAATTAGTCTTCCATCGG	POC1B	ENSG00000139323	-0.5549958189549642	[41]	[24,29]	-7	hSpCas9	negative selection	3252197
89491950	89491973		+	24336571	A375	viability after 14 days	CCAGTGTGTATGTCGATACAAGG	POC1B	ENSG00000139323	0.34705751931346374	[40]	[52,45]	4	hSpCas9	negative selection	3309986
89491950	89491973		-	24336571	A375	viability after 14 days	CCTTGTATCGACATACACACTGG	POC1B	ENSG00000139323	-0.06998681368935333	[34]	[26,34]	-1	hSpCas9	negative selection	3309987
89472261	89472284		-	24336571	A375	viability after 14 days	CTTTCTAGATTTTCACCCGATGG	POC1B	ENSG00000139323	-1.2293127980501768	[12]	[5,3]	-9	hSpCas9	negative selection	3309988
89472245	89472268		+	24336571	A375	viability after 14 days	TGACACAATTAGTCTTCCATCGG	POC1B	ENSG00000139323	-0.9829503849044829	[41]	[20,17]	-8	hSpCas9	negative selection	3309990
89472235	89472258	12	-	27383988	293T	resistance to West Nile virus (flavivirus)	ACTAATTGTGTCATGTAGTGAGG	POC1B	ENSG00000139323	0.8650087886670746	[83,83]	[0,0]	4	hSpCas9	positive selection	3386599
89472168	89472191	12	-	27383988	293T	resistance to West Nile virus (flavivirus)	AATAACTTCTCAGATTCCGTTGG	POC1B	ENSG00000139323	-0.3049162127752376	[188,188]	[0,0]	-2	hSpCas9	positive selection	3386600
89472152	89472175	12	+	26780180	HT29	viability (Avana library 4 designs)	AAGAAAGTGTACTTACCCAACGG	POC1B	ENSG00000139323	2.36103549833952	[]	[]	8	hSpCas9	negative selection	3450425
89472167	89472190	12	-	26780180	HT29	viability (Avana library 4 designs)	ATAACTTCTCAGATTCCGTTGGG	POC1B	ENSG00000139323	0.204833621166027	[]	[]	0	hSpCas9	negative selection	3450426
89491950	89491973	12	-	26780180	HT29	viability (Avana library 4 designs)	CCTTGTATCGACATACACACTGG	POC1B	ENSG00000139323	0.26964812803758	[]	[]	0	hSpCas9	negative selection	3450427
89470437	89470460	12	+	26780180	HT29	viability (Avana library 4 designs)	GTGATGAGATAGTTACCCGAAGG	POC1B	ENSG00000139323	1.25815855265022	[]	[]	5	hSpCas9	negative selection	3450428
89472152	89472175	12	+	26780180	A375	viability (Avana lentiCRISPRv2)	AAGAAAGTGTACTTACCCAACGG	POC1B	ENSG00000139323	-5.37725324289334	[]	[]	-5	hSpCas9	negative selection	3545662
89472167	89472190	12	-	26780180	A375	viability (Avana lentiCRISPRv2)	ATAACTTCTCAGATTCCGTTGGG	POC1B	ENSG00000139323	-10.468638308647	[]	[]	-8	hSpCas9	negative selection	3545663
89470437	89470460	12	+	26780180	A375	viability (Avana lentiCRISPRv2)	GTGATGAGATAGTTACCCGAAGG	POC1B	ENSG00000139323	1.99733613788122	[]	[]	3	hSpCas9	negative selection	3545664
89491950	89491973	12	-	26780180	A375	viability (Avana lentiCRISPRv2)	CCTTGTATCGACATACACACTGG	POC1B	ENSG00000139323	0.177230064515261	[]	[]	0	hSpCas9	negative selection	3545665
89470485	89470508	12	-	26780180	A375	viability (Avana lentiCRISPRv2)	TTCTACAAATCAGTTCACAGCGG	POC1B	ENSG00000139323	-4.92847051329503	[]	[]	-5	hSpCas9	negative selection	3545666
89470381	89470404	12	+	26780180	A375	viability (Avana lentiCRISPRv2)	AGATGAGCCTTCCTTCTAAGAGG	POC1B	ENSG00000139323	0.783091803807088	[]	[]	1	hSpCas9	negative selection	3545667
89472152	89472175	12	+	26780180	A375	viability (Avana lentiGuide)	AAGAAAGTGTACTTACCCAACGG	POC1B	ENSG00000139323	1.48013483822799	[]	[]	1	hSpCas9	negative selection	3654321
89472167	89472190	12	-	26780180	A375	viability (Avana lentiGuide)	ATAACTTCTCAGATTCCGTTGGG	POC1B	ENSG00000139323	-0.239211497248291	[]	[]	0	hSpCas9	negative selection	3654322
89470437	89470460	12	+	26780180	A375	viability (Avana lentiGuide)	GTGATGAGATAGTTACCCGAAGG	POC1B	ENSG00000139323	-4.59660145712765	[]	[]	-7	hSpCas9	negative selection	3654323
89491950	89491973	12	-	26780180	A375	viability (Avana lentiGuide)	CCTTGTATCGACATACACACTGG	POC1B	ENSG00000139323	1.38789541189288	[]	[]	1	hSpCas9	negative selection	3654324
89470485	89470508	12	-	26780180	A375	viability (Avana lentiGuide)	TTCTACAAATCAGTTCACAGCGG	POC1B	ENSG00000139323	-2.82845643146516	[]	[]	-5	hSpCas9	negative selection	3654325
89470381	89470404	12	+	26780180	A375	viability (Avana lentiGuide)	AGATGAGCCTTCCTTCTAAGAGG	POC1B	ENSG00000139323	1.1165723974441	[]	[]	1	hSpCas9	negative selection	3654326
89472152	89472175	12	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AAGAAAGTGTACTTACCCAACGG	POC1B	ENSG00000139323	-0.380788559320906	[6]	[5,3]	-5	hSpCas9	positive selection	3762980
89472167	89472190	12	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ATAACTTCTCAGATTCCGTTGGG	POC1B	ENSG00000139323	-0.2561562333185257	[6]	[5,4]	-4	hSpCas9	positive selection	3762981
89470437	89470460	12	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GTGATGAGATAGTTACCCGAAGG	POC1B	ENSG00000139323	0.07631134191052209	[5]	[6,4]	2	hSpCas9	positive selection	3762982
89491950	89491973	12	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CCTTGTATCGACATACACACTGG	POC1B	ENSG00000139323	-0.27479608860187604	[4]	[3,2]	-4	hSpCas9	positive selection	3762983
89470485	89470508	12	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TTCTACAAATCAGTTCACAGCGG	POC1B	ENSG00000139323	-0.4948934564988727	[6]	[4,3]	-6	hSpCas9	positive selection	3762984
89470381	89470404	12	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AGATGAGCCTTCCTTCTAAGAGG	POC1B	ENSG00000139323	0.15825496563003857	[5]	[5,6]	4	hSpCas9	positive selection	3762985
89472152	89472175	12	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AAGAAAGTGTACTTACCCAACGG	POC1B	ENSG00000139323	0.004730468735236457	[5]	[4,4]	0	hSpCas9	positive selection	3871587
89472167	89472190	12	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ATAACTTCTCAGATTCCGTTGGG	POC1B	ENSG00000139323	-0.27442168583595594	[5]	[4,2]	-4	hSpCas9	positive selection	3871588
89470437	89470460	12	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GTGATGAGATAGTTACCCGAAGG	POC1B	ENSG00000139323	0.36563616873525895	[5]	[6,5]	9	hSpCas9	positive selection	3871589
89491950	89491973	12	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CCTTGTATCGACATACACACTGG	POC1B	ENSG00000139323	-1.3335270378952135	[3]	[1,0]	-9	hSpCas9	positive selection	3871590
89470485	89470508	12	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TTCTACAAATCAGTTCACAGCGG	POC1B	ENSG00000139323	0.2743547929413566	[5]	[6,5]	7	hSpCas9	positive selection	3871591
89470381	89470404	12	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AGATGAGCCTTCCTTCTAAGAGG	POC1B	ENSG00000139323	0.11579769179465746	[6]	[5,5]	2	hSpCas9	positive selection	3871592
89472168	89472191	12	-	26780180	A375	viability	AATAACTTCTCAGATTCCGTTGG	POC1B	ENSG00000139323	0.882601638294875	[]	[]	3	hSpCas9	negative selection	3982418
89472235	89472258	12	-	26780180	A375	viability	ACTAATTGTGTCATGTAGTGAGG	POC1B	ENSG00000139323	0.787118100859751	[]	[]	3	hSpCas9	negative selection	3982419
89491950	89491973	12	+	26780180	A375	viability	CCAGTGTGTATGTCGATACAAGG	POC1B	ENSG00000139323	0.999204323466001	[]	[]	4	hSpCas9	negative selection	3982420
89491950	89491973	12	-	26780180	A375	viability	CCTTGTATCGACATACACACTGG	POC1B	ENSG00000139323	0.735716631035339	[]	[]	2	hSpCas9	negative selection	3982421
89472168	89472191	12	-	26780180	HT29	viability (GeCKOv2 library)	AATAACTTCTCAGATTCCGTTGG	POC1B	ENSG00000139323	0.823431525386223	[]	[]	3	hSpCas9	negative selection	4090384
89472235	89472258	12	-	26780180	HT29	viability (GeCKOv2 library)	ACTAATTGTGTCATGTAGTGAGG	POC1B	ENSG00000139323	1.62919708773552	[]	[]	8	hSpCas9	negative selection	4090385
89491950	89491973	12	+	26780180	HT29	viability (GeCKOv2 library)	CCAGTGTGTATGTCGATACAAGG	POC1B	ENSG00000139323	0.687038347868692	[]	[]	2	hSpCas9	negative selection	4090386
89491950	89491973	12	-	26780180	HT29	viability (GeCKOv2 library)	CCTTGTATCGACATACACACTGG	POC1B	ENSG00000139323	0.576582330441427	[]	[]	2	hSpCas9	negative selection	4090387
89491950	89491973	12	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CCAGTGTGTATGTCGATACAAGG	POC1B	ENSG00000139323	0.2793486825333394	[5]	[4,4]	7	hSpCas9	positive selection	4161643
89491950	89491973	12	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CCTTGTATCGACATACACACTGG	POC1B	ENSG00000139323	0.1502089588383163	[4]	[3,4]	4	hSpCas9	positive selection	4161644
89472261	89472284	12	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CTTTCTAGATTTTCACCCGATGG	POC1B	ENSG00000139323	0.29789654623676076	[3]	[1,3]	7	hSpCas9	positive selection	4161645
89472245	89472268	12	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TGACACAATTAGTCTTCCATCGG	POC1B	ENSG00000139323	-0.13861772701802522	[4]	[3,2]	-3	hSpCas9	positive selection	4161647
89491950	89491973	12	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CCAGTGTGTATGTCGATACAAGG	POC1B	ENSG00000139323	1.005992022155779	[4]	[1,6,3,4]	7	hSpCas9	positive selection	4225665
89491950	89491973	12	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CCTTGTATCGACATACACACTGG	POC1B	ENSG00000139323	0.1817730864877689	[5]	[4,4,2,0]	1	hSpCas9	positive selection	4225666
89472261	89472284	12	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CTTTCTAGATTTTCACCCGATGG	POC1B	ENSG00000139323	-0.6889386898759056	[3]	[0,0,0,0]	-8	hSpCas9	positive selection	4225667
89472245	89472268	12	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TGACACAATTAGTCTTCCATCGG	POC1B	ENSG00000139323	0.1583794886922662	[4]	[2,2,5,0]	1	hSpCas9	positive selection	4225669
89491950	89491973	12	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCTTGTATCGACATACACACTGG	POC1B	ENSG00000139323	0.0784332765975414	[4]	[3,3]	1	hSpCas9	positive selection	4291094
89491950	89491973	12	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCAGTGTGTATGTCGATACAAGG	POC1B	ENSG00000139323	-0.0844917950762854	[3]	[3,1]	-2	hSpCas9	positive selection	4291095
89472235	89472258	12	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ACTAATTGTGTCATGTAGTGAGG	POC1B	ENSG00000139323	0.06052996397347299	[2]	[1,1]	1	hSpCas9	positive selection	4355343
89472168	89472191	12	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AATAACTTCTCAGATTCCGTTGG	POC1B	ENSG00000139323	0.11279510142810151	[3]	[2,2]	2	hSpCas9	positive selection	4355344
89470442	89470464	12	+	27760321	OCIAML3	viability	GAGATAGTTACCCGAAGGATGG	POC1B	ENSG00000139323	-0.029385953985813007	[118,122]	[80,108]	0	hSpCas9	negative selection	4429067
89471613	89471635	12	-	27760321	OCIAML3	viability	AATTACTACAGCATTACCAAGG	POC1B	ENSG00000139323	0.1148512263741499	[65,54]	[37,67]	1	hSpCas9	negative selection	4429068
89471676	89471698	12	-	27760321	OCIAML3	viability	GTACATGCATAGCTTCAGCAGG	POC1B	ENSG00000139323	0.2928154898865003	[409,377]	[340,424]	3	hSpCas9	negative selection	4429069
89472261	89472283	12	-	27760321	OCIAML3	viability	TTTCTAGATTTTCACCCGATGG	POC1B	ENSG00000139323	0.3555302554588896	[688,699]	[688,708]	4	hSpCas9	negative selection	4429070
89491950	89491972	12	-	27760321	OCIAML3	viability	CTTGTATCGACATACACACTGG	POC1B	ENSG00000139323	-0.6428160623121413	[268,242]	[118,139]	-6	hSpCas9	negative selection	4429071
89470442	89470464	12	+	27760321	OCIAML2	viability	GAGATAGTTACCCGAAGGATGG	POC1B	ENSG00000139323	0.7487365466237805	[118,122]	[150,183]	8	hSpCas9	negative selection	4512530
89471613	89471635	12	-	27760321	OCIAML2	viability	AATTACTACAGCATTACCAAGG	POC1B	ENSG00000139323	-0.5622108948875582	[65,54]	[10,61]	-6	hSpCas9	negative selection	4512531
89471676	89471698	12	-	27760321	OCIAML2	viability	GTACATGCATAGCTTCAGCAGG	POC1B	ENSG00000139323	0.30882506379908903	[409,377]	[320,491]	4	hSpCas9	negative selection	4512532
89472261	89472283	12	-	27760321	OCIAML2	viability	TTTCTAGATTTTCACCCGATGG	POC1B	ENSG00000139323	0.4197005806622117	[688,699]	[621,928]	6	hSpCas9	negative selection	4512533
89491950	89491972	12	-	27760321	OCIAML2	viability	CTTGTATCGACATACACACTGG	POC1B	ENSG00000139323	0.15996825264000603	[268,242]	[184,291]	2	hSpCas9	negative selection	4512534
89470442	89470464	12	+	27760321	MV411	viability	GAGATAGTTACCCGAAGGATGG	POC1B	ENSG00000139323	-2.418814381987566	[118,122]	[16,11]	-9	hSpCas9	negative selection	4595993
89471613	89471635	12	-	27760321	MV411	viability	AATTACTACAGCATTACCAAGG	POC1B	ENSG00000139323	1.9030671187304478	[65,54]	[21,338]	9	hSpCas9	negative selection	4595994
89471676	89471698	12	-	27760321	MV411	viability	GTACATGCATAGCTTCAGCAGG	POC1B	ENSG00000139323	-1.0658113468595087	[409,377]	[120,128]	-6	hSpCas9	negative selection	4595995
89472261	89472283	12	-	27760321	MV411	viability	TTTCTAGATTTTCACCCGATGG	POC1B	ENSG00000139323	0.44908958083230177	[688,699]	[536,764]	3	hSpCas9	negative selection	4595996
89491950	89491972	12	-	27760321	MV411	viability	CTTGTATCGACATACACACTGG	POC1B	ENSG00000139323	-0.4860463252880034	[268,242]	[10,284]	-3	hSpCas9	negative selection	4595997
89470442	89470464	12	+	27760321	HL60	viability	GAGATAGTTACCCGAAGGATGG	POC1B	ENSG00000139323	2.29884460408968	[118,122]	[442,536]	9	hSpCas9	negative selection	4679456
89471613	89471635	12	-	27760321	HL60	viability	AATTACTACAGCATTACCAAGG	POC1B	ENSG00000139323	-0.2980299264977444	[65,54]	[40,38]	-3	hSpCas9	negative selection	4679457
89471676	89471698	12	-	27760321	HL60	viability	GTACATGCATAGCTTCAGCAGG	POC1B	ENSG00000139323	0.33264899577023893	[409,377]	[414,394]	4	hSpCas9	negative selection	4679458
89472261	89472283	12	-	27760321	HL60	viability	TTTCTAGATTTTCACCCGATGG	POC1B	ENSG00000139323	0.6910942246893389	[688,699]	[771,1075]	7	hSpCas9	negative selection	4679459
89491950	89491972	12	-	27760321	HL60	viability	CTTGTATCGACATACACACTGG	POC1B	ENSG00000139323	-0.6625666332767446	[268,242]	[164,96]	-6	hSpCas9	negative selection	4679460
89470442	89470464	12	+	27760321	HT1080	viability	GAGATAGTTACCCGAAGGATGG	POC1B	ENSG00000139323	0.6530026707878025	[122,95]	[59,77]	3	hSpCas9	negative selection	4762919
89471613	89471635	12	-	27760321	HT1080	viability	AATTACTACAGCATTACCAAGG	POC1B	ENSG00000139323	-4.287047653924705	[54,42]	[0,0]	-8	hSpCas9	negative selection	4762920
89471676	89471698	12	-	27760321	HT1080	viability	GTACATGCATAGCTTCAGCAGG	POC1B	ENSG00000139323	1.2525668776178365	[377,294]	[527,90]	6	hSpCas9	negative selection	4762921
89472261	89472283	12	-	27760321	HT1080	viability	TTTCTAGATTTTCACCCGATGG	POC1B	ENSG00000139323	0.6722711499764398	[699,545]	[605,164]	3	hSpCas9	negative selection	4762922
89491950	89491972	12	-	27760321	HT1080	viability	CTTGTATCGACATACACACTGG	POC1B	ENSG00000139323	0.3680518131054529	[242,189]	[75,149]	2	hSpCas9	negative selection	4762923
89470442	89470464	12	+	27760321	HT29	viability after 7 days	GAGATAGTTACCCGAAGGATGG	POC1B	ENSG00000139323	-0.5797424671955902	[122,95]	[113,99,71]	-7	hSpCas9	negative selection	4846382
89471613	89471635	12	-	27760321	HT29	viability after 7 days	AATTACTACAGCATTACCAAGG	POC1B	ENSG00000139323	-0.09604090000942112	[54,42]	[35,62,73]	-1	hSpCas9	negative selection	4846383
89471676	89471698	12	-	27760321	HT29	viability after 7 days	GTACATGCATAGCTTCAGCAGG	POC1B	ENSG00000139323	0.12636937460453368	[377,294]	[667,431,347]	2	hSpCas9	negative selection	4846384
89472261	89472283	12	-	27760321	HT29	viability after 7 days	TTTCTAGATTTTCACCCGATGG	POC1B	ENSG00000139323	-0.33304709140097566	[699,545]	[843,477,614]	-5	hSpCas9	negative selection	4846385
89491950	89491972	12	-	27760321	HT29	viability after 7 days	CTTGTATCGACATACACACTGG	POC1B	ENSG00000139323	-1.0170061866176465	[242,189]	[277,95,60]	-8	hSpCas9	negative selection	4846386
89470442	89470464	12	+	27760321	HT29	viability after 25 days	GAGATAGTTACCCGAAGGATGG	POC1B	ENSG00000139323	-0.30218685558617775	[122,95]	[96,162,37]	-3	hSpCas9	negative selection	4929845
89471613	89471635	12	-	27760321	HT29	viability after 25 days	AATTACTACAGCATTACCAAGG	POC1B	ENSG00000139323	-0.18520604234439864	[54,42]	[2,94,52]	-2	hSpCas9	negative selection	4929846
89471676	89471698	12	-	27760321	HT29	viability after 25 days	GTACATGCATAGCTTCAGCAGG	POC1B	ENSG00000139323	0.4214810239303277	[377,294]	[514,680,328]	4	hSpCas9	negative selection	4929847
89472261	89472283	12	-	27760321	HT29	viability after 25 days	TTTCTAGATTTTCACCCGATGG	POC1B	ENSG00000139323	-0.18184947882604363	[699,545]	[641,542,703]	-2	hSpCas9	negative selection	4929848
89491950	89491972	12	-	27760321	HT29	viability after 25 days	CTTGTATCGACATACACACTGG	POC1B	ENSG00000139323	-0.27287418304605926	[242,189]	[341,122,132]	-3	hSpCas9	negative selection	4929849
89470442	89470464	12	+	27760321	HT29	viability after 22 days	GAGATAGTTACCCGAAGGATGG	POC1B	ENSG00000139323	0.3432416050237821	[122,95]	[206,165,106]	3	hSpCas9	negative selection	5013308
89471613	89471635	12	-	27760321	HT29	viability after 22 days	AATTACTACAGCATTACCAAGG	POC1B	ENSG00000139323	0.7313186225319175	[54,42]	[129,75,74]	8	hSpCas9	negative selection	5013309
89471676	89471698	12	-	27760321	HT29	viability after 22 days	GTACATGCATAGCTTCAGCAGG	POC1B	ENSG00000139323	0.33810026907882257	[377,294]	[325,524,629]	3	hSpCas9	negative selection	5013310
89472261	89472283	12	-	27760321	HT29	viability after 22 days	TTTCTAGATTTTCACCCGATGG	POC1B	ENSG00000139323	-0.3903781087762695	[699,545]	[512,516,619]	-4	hSpCas9	negative selection	5013311
89491950	89491972	12	-	27760321	HT29	viability after 22 days	CTTGTATCGACATACACACTGG	POC1B	ENSG00000139323	-0.5633115658723216	[242,189]	[76,126,307]	-5	hSpCas9	negative selection	5013312
89470442	89470464	12	+	27760321	HT29	viability after 19 days	GAGATAGTTACCCGAAGGATGG	POC1B	ENSG00000139323	-0.3353974686265193	[122,95]	[134,108,58]	-3	hSpCas9	negative selection	5096771
89471613	89471635	12	-	27760321	HT29	viability after 19 days	AATTACTACAGCATTACCAAGG	POC1B	ENSG00000139323	-0.20177783995124265	[54,42]	[86,9,52]	-2	hSpCas9	negative selection	5096772
89471676	89471698	12	-	27760321	HT29	viability after 19 days	GTACATGCATAGCTTCAGCAGG	POC1B	ENSG00000139323	-0.2572362371472511	[377,294]	[521,230,236]	-2	hSpCas9	negative selection	5096773
89472261	89472283	12	-	27760321	HT29	viability after 19 days	TTTCTAGATTTTCACCCGATGG	POC1B	ENSG00000139323	-0.26385638193591343	[699,545]	[825,246,725]	-3	hSpCas9	negative selection	5096774
89491950	89491972	12	-	27760321	HT29	viability after 19 days	CTTGTATCGACATACACACTGG	POC1B	ENSG00000139323	-0.8751197680139078	[242,189]	[361,19,49]	-6	hSpCas9	negative selection	5096775
89470442	89470464	12	+	27760321	HT29	viability after 16 days	GAGATAGTTACCCGAAGGATGG	POC1B	ENSG00000139323	-1.168487972402207	[122,95]	[35,44,80]	-7	hSpCas9	negative selection	5180234
89471613	89471635	12	-	27760321	HT29	viability after 16 days	AATTACTACAGCATTACCAAGG	POC1B	ENSG00000139323	0.26473217367219215	[54,42]	[80,66,50]	3	hSpCas9	negative selection	5180235
89471676	89471698	12	-	27760321	HT29	viability after 16 days	GTACATGCATAGCTTCAGCAGG	POC1B	ENSG00000139323	-0.051604855875040406	[377,294]	[355,324,408]	0	hSpCas9	negative selection	5180236
89472261	89472283	12	-	27760321	HT29	viability after 16 days	TTTCTAGATTTTCACCCGATGG	POC1B	ENSG00000139323	-0.09953354971288197	[699,545]	[659,472,823]	-1	hSpCas9	negative selection	5180237
89491950	89491972	12	-	27760321	HT29	viability after 16 days	CTTGTATCGACATACACACTGG	POC1B	ENSG00000139323	-0.1637555829080095	[242,189]	[347,222,89]	-2	hSpCas9	negative selection	5180238
89470442	89470464	12	+	27760321	HT29	viability after 13 days	GAGATAGTTACCCGAAGGATGG	POC1B	ENSG00000139323	-0.8445001014153339	[122,95]	[77,59,73]	-7	hSpCas9	negative selection	5263697
89471613	89471635	12	-	27760321	HT29	viability after 13 days	AATTACTACAGCATTACCAAGG	POC1B	ENSG00000139323	0.02923597970188574	[54,42]	[72,42,57]	0	hSpCas9	negative selection	5263698
89471676	89471698	12	-	27760321	HT29	viability after 13 days	GTACATGCATAGCTTCAGCAGG	POC1B	ENSG00000139323	-0.012566561361386272	[377,294]	[339,450,370]	0	hSpCas9	negative selection	5263699
89472261	89472283	12	-	27760321	HT29	viability after 13 days	TTTCTAGATTTTCACCCGATGG	POC1B	ENSG00000139323	-0.1767955361947685	[699,545]	[747,466,698]	-2	hSpCas9	negative selection	5263700
89491950	89491972	12	-	27760321	HT29	viability after 13 days	CTTGTATCGACATACACACTGG	POC1B	ENSG00000139323	0.15898441430722432	[242,189]	[470,210,165]	2	hSpCas9	negative selection	5263701
89470442	89470464	12	+	27760321	HT29	viability after 10 days	GAGATAGTTACCCGAAGGATGG	POC1B	ENSG00000139323	-0.08936214002924392	[122,95]	[218,37,125]	-1	hSpCas9	negative selection	5347160
89471613	89471635	12	-	27760321	HT29	viability after 10 days	AATTACTACAGCATTACCAAGG	POC1B	ENSG00000139323	-0.19176747943523642	[54,42]	[54,98,8]	-2	hSpCas9	negative selection	5347161
89471676	89471698	12	-	27760321	HT29	viability after 10 days	GTACATGCATAGCTTCAGCAGG	POC1B	ENSG00000139323	0.2065012337447043	[377,294]	[488,456,506]	2	hSpCas9	negative selection	5347162
89472261	89472283	12	-	27760321	HT29	viability after 10 days	TTTCTAGATTTTCACCCGATGG	POC1B	ENSG00000139323	-0.25344954067810876	[699,545]	[534,736,686]	-3	hSpCas9	negative selection	5347163
89491950	89491972	12	-	27760321	HT29	viability after 10 days	CTTGTATCGACATACACACTGG	POC1B	ENSG00000139323	-0.5365913967011691	[242,189]	[198,218,142]	-6	hSpCas9	negative selection	5347164
89470442	89470464	12	+	27760321	MOLM13	viability	GAGATAGTTACCCGAAGGATGG	POC1B	ENSG00000139323	1.7040770667352279	[118,122]	[418,56]	9	hSpCas9	negative selection	5430623
89471613	89471635	12	-	27760321	MOLM13	viability	AATTACTACAGCATTACCAAGG	POC1B	ENSG00000139323	1.152046569134009	[65,54]	[148,12]	7	hSpCas9	negative selection	5430624
89471676	89471698	12	-	27760321	MOLM13	viability	GTACATGCATAGCTTCAGCAGG	POC1B	ENSG00000139323	-0.08175126670637028	[409,377]	[222,198]	0	hSpCas9	negative selection	5430625
89472261	89472283	12	-	27760321	MOLM13	viability	TTTCTAGATTTTCACCCGATGG	POC1B	ENSG00000139323	0.3095042922262221	[688,699]	[547,435]	2	hSpCas9	negative selection	5430626
89491950	89491972	12	-	27760321	MOLM13	viability	CTTGTATCGACATACACACTGG	POC1B	ENSG00000139323	-1.2882351843850743	[268,242]	[104,19]	-6	hSpCas9	negative selection	5430627
89491950	89491973	12	-	27260156	BXPC3	viability	CCTTGTATCGACATACACACTGG	POC1B	ENSG00000139323	0.11040905494665831	[1533]	[1698,1524,1869,1852]	2	hSpCas9	negative selection	5563554
89491950	89491973	12	+	27260156	BXPC3	viability	CCAGTGTGTATGTCGATACAAGG	POC1B	ENSG00000139323	-0.26217487873368406	[931]	[785,805,762,902]	-5	hSpCas9	negative selection	5563555
89472235	89472258	12	-	27260156	BXPC3	viability	ACTAATTGTGTCATGTAGTGAGG	POC1B	ENSG00000139323	-0.3438249635230828	[201]	[65,167,263,180]	-6	hSpCas9	negative selection	5627803
89472168	89472191	12	-	27260156	BXPC3	viability	AATAACTTCTCAGATTCCGTTGG	POC1B	ENSG00000139323	-0.15000514863003098	[487]	[329,503,410,621]	-3	hSpCas9	negative selection	5627804
89491950	89491973	12	-	27260156	A673	viability	CCTTGTATCGACATACACACTGG	POC1B	ENSG00000139323	0.09488946469392467	[1533]	[2094,1806,2015,1964]	2	hSpCas9	negative selection	5684805
89491950	89491973	12	+	27260156	A673	viability	CCAGTGTGTATGTCGATACAAGG	POC1B	ENSG00000139323	-0.30974607925303943	[931]	[1104,941,813,763]	-6	hSpCas9	negative selection	5684806
89472235	89472258	12	-	27260156	A673	viability	ACTAATTGTGTCATGTAGTGAGG	POC1B	ENSG00000139323	-0.39278594973180736	[201]	[186,204,110,238]	-7	hSpCas9	negative selection	5749054
89472168	89472191	12	-	27260156	A673	viability	AATAACTTCTCAGATTCCGTTGG	POC1B	ENSG00000139323	0.046065760675410274	[487]	[609,464,619,734]	1	hSpCas9	negative selection	5749055
89491950	89491973	12	-	27260156	A375	viability	CCTTGTATCGACATACACACTGG	POC1B	ENSG00000139323	0.26449954917499063	[1533]	[1946,2798,1800,2142]	4	hSpCas9	negative selection	5806056
89491950	89491973	12	+	27260156	A375	viability	CCAGTGTGTATGTCGATACAAGG	POC1B	ENSG00000139323	0.0007589636986700121	[931]	[1082,1246,943,1098]	0	hSpCas9	negative selection	5806057
89472235	89472258	12	-	27260156	A375	viability	ACTAATTGTGTCATGTAGTGAGG	POC1B	ENSG00000139323	0.24835110513428293	[201]	[380,293,235,218]	3	hSpCas9	negative selection	5870305
89472168	89472191	12	-	27260156	A375	viability	AATAACTTCTCAGATTCCGTTGG	POC1B	ENSG00000139323	-0.27990184638711957	[487]	[457,413,533,462]	-4	hSpCas9	negative selection	5870306
89491950	89491973	12	-	27260156	COLO741	viability	CCTTGTATCGACATACACACTGG	POC1B	ENSG00000139323	-0.06337135839007679	[1533]	[2038,2214,1417]	-1	hSpCas9	negative selection	5927307
89491950	89491973	12	+	27260156	COLO741	viability	CCAGTGTGTATGTCGATACAAGG	POC1B	ENSG00000139323	-0.21702978173884846	[931]	[1161,1068,863]	-5	hSpCas9	negative selection	5927308
89472235	89472258	12	-	27260156	COLO741	viability	ACTAATTGTGTCATGTAGTGAGG	POC1B	ENSG00000139323	-0.4524007639154486	[201]	[228,181,159]	-7	hSpCas9	negative selection	5991556
89472168	89472191	12	-	27260156	COLO741	viability	AATAACTTCTCAGATTCCGTTGG	POC1B	ENSG00000139323	-0.199991271214186	[487]	[544,561,521]	-4	hSpCas9	negative selection	5991557
89491950	89491973	12	-	27260156	CAL120	viability	CCTTGTATCGACATACACACTGG	POC1B	ENSG00000139323	-0.09599779708560363	[1533]	[1913,1590,1869]	-1	hSpCas9	negative selection	6048558
89491950	89491973	12	+	27260156	CAL120	viability	CCAGTGTGTATGTCGATACAAGG	POC1B	ENSG00000139323	-0.5584082859939978	[931]	[958,747,682]	-7	hSpCas9	negative selection	6048559
89472235	89472258	12	-	27260156	CAL120	viability	ACTAATTGTGTCATGTAGTGAGG	POC1B	ENSG00000139323	-0.39723360454073275	[201]	[82,433,41]	-5	hSpCas9	negative selection	6112807
89472168	89472191	12	-	27260156	CAL120	viability	AATAACTTCTCAGATTCCGTTGG	POC1B	ENSG00000139323	-0.46270257287790145	[487]	[643,471,239]	-6	hSpCas9	negative selection	6112808
89491950	89491973	12	-	27260156	CADOES1	viability	CCTTGTATCGACATACACACTGG	POC1B	ENSG00000139323	0.08144387445343226	[1533]	[1574,1847,1281,1326]	1	hSpCas9	negative selection	6169809
89491950	89491973	12	+	27260156	CADOES1	viability	CCAGTGTGTATGTCGATACAAGG	POC1B	ENSG00000139323	-0.3089432432511313	[931]	[684,706,730,674]	-5	hSpCas9	negative selection	6169810
89472235	89472258	12	-	27260156	CADOES1	viability	ACTAATTGTGTCATGTAGTGAGG	POC1B	ENSG00000139323	-0.36711219622722346	[201]	[105,226,127,120]	-6	hSpCas9	negative selection	6234058
89472168	89472191	12	-	27260156	CADOES1	viability	AATAACTTCTCAGATTCCGTTGG	POC1B	ENSG00000139323	-0.2778093596883846	[487]	[418,356,380,338]	-5	hSpCas9	negative selection	6234059
89491950	89491973	12	-	27260156	EWS502	viability	CCTTGTATCGACATACACACTGG	POC1B	ENSG00000139323	-0.10240242021239432	[1533]	[1212,1551,1549,1787]	-2	hSpCas9	negative selection	6291060
89491950	89491973	12	+	27260156	EWS502	viability	CCAGTGTGTATGTCGATACAAGG	POC1B	ENSG00000139323	-0.4838524542180921	[931]	[709,660,659,796]	-7	hSpCas9	negative selection	6291061
89472235	89472258	12	-	27260156	EWS502	viability	ACTAATTGTGTCATGTAGTGAGG	POC1B	ENSG00000139323	-0.19002108496631243	[201]	[231,196,187,121]	-3	hSpCas9	negative selection	6355309
89472168	89472191	12	-	27260156	EWS502	viability	AATAACTTCTCAGATTCCGTTGG	POC1B	ENSG00000139323	-0.324461857989736	[487]	[302,514,409,431]	-5	hSpCas9	negative selection	6355310
89491950	89491973	12	-	27260156	EW8	viability	CCTTGTATCGACATACACACTGG	POC1B	ENSG00000139323	0.16083549362382477	[1533]	[1745,1482,1053,1368]	3	hSpCas9	negative selection	6412311
89491950	89491973	12	+	27260156	EW8	viability	CCAGTGTGTATGTCGATACAAGG	POC1B	ENSG00000139323	-0.41990164512985095	[931]	[519,580,622,517]	-6	hSpCas9	negative selection	6412312
89472235	89472258	12	-	27260156	EW8	viability	ACTAATTGTGTCATGTAGTGAGG	POC1B	ENSG00000139323	-0.09844872430553364	[201]	[161,171,142,136]	-2	hSpCas9	negative selection	6476560
89472168	89472191	12	-	27260156	EW8	viability	AATAACTTCTCAGATTCCGTTGG	POC1B	ENSG00000139323	-0.11133554789817524	[487]	[487,324,268,410]	-2	hSpCas9	negative selection	6476561
89491950	89491973	12	-	27260156	CORL105	viability	CCTTGTATCGACATACACACTGG	POC1B	ENSG00000139323	0.04814710655013532	[1533]	[1721,1715,2472,1610]	0	hSpCas9	negative selection	6533562
89491950	89491973	12	+	27260156	CORL105	viability	CCAGTGTGTATGTCGATACAAGG	POC1B	ENSG00000139323	-0.5180772059872047	[931]	[823,547,942,766]	-7	hSpCas9	negative selection	6533563
89472235	89472258	12	-	27260156	CORL105	viability	ACTAATTGTGTCATGTAGTGAGG	POC1B	ENSG00000139323	-0.7012683571130585	[201]	[223,102,167,93]	-8	hSpCas9	negative selection	6597811
89472168	89472191	12	-	27260156	CORL105	viability	AATAACTTCTCAGATTCCGTTGG	POC1B	ENSG00000139323	-0.47269922974315937	[487]	[298,342,640,396]	-7	hSpCas9	negative selection	6597812
89491950	89491973	12	-	27260156	HS294T	viability	CCTTGTATCGACATACACACTGG	POC1B	ENSG00000139323	0.20730465435998835	[1533]	[637,652,743,711]	3	hSpCas9	negative selection	6654813
89491950	89491973	12	+	27260156	HS294T	viability	CCAGTGTGTATGTCGATACAAGG	POC1B	ENSG00000139323	-0.18744919454905873	[931]	[392,297,274,286]	-3	hSpCas9	negative selection	6654814
89472235	89472258	12	-	27260156	HS294T	viability	ACTAATTGTGTCATGTAGTGAGG	POC1B	ENSG00000139323	1.0339647050941143	[201]	[89,367,49,124]	9	hSpCas9	negative selection	6719062
89472168	89472191	12	-	27260156	HS294T	viability	AATAACTTCTCAGATTCCGTTGG	POC1B	ENSG00000139323	-0.27224358489075234	[487]	[99,195,188,140]	-4	hSpCas9	negative selection	6719063
89491950	89491973	12	-	27260156	HCC44	viability	CCTTGTATCGACATACACACTGG	POC1B	ENSG00000139323	-0.4566467512364756	[1533]	[1377,1088,1519,1142]	-6	hSpCas9	negative selection	6776064
89491950	89491973	12	+	27260156	HCC44	viability	CCAGTGTGTATGTCGATACAAGG	POC1B	ENSG00000139323	-0.23814200479332626	[931]	[884,763,1413,620]	-4	hSpCas9	negative selection	6776065
89472235	89472258	12	-	27260156	HCC44	viability	ACTAATTGTGTCATGTAGTGAGG	POC1B	ENSG00000139323	-0.27222205667395594	[201]	[59,101,435,199]	-4	hSpCas9	negative selection	6840313
89472168	89472191	12	-	27260156	HCC44	viability	AATAACTTCTCAGATTCCGTTGG	POC1B	ENSG00000139323	-1.1754156901967474	[487]	[251,209,238,277]	-9	hSpCas9	negative selection	6840314
89491950	89491973	12	-	27260156	G402	viability	CCTTGTATCGACATACACACTGG	POC1B	ENSG00000139323	0.2430423792556229	[1533]	[2364,2712,1929,1909]	3	hSpCas9	negative selection	6897315
89491950	89491973	12	+	27260156	G402	viability	CCAGTGTGTATGTCGATACAAGG	POC1B	ENSG00000139323	-0.24636496108311512	[931]	[819,832,1154,993]	-3	hSpCas9	negative selection	6897316
89472235	89472258	12	-	27260156	G402	viability	ACTAATTGTGTCATGTAGTGAGG	POC1B	ENSG00000139323	0.5224114624000536	[201]	[272,527,296,316]	6	hSpCas9	negative selection	6961564
89472168	89472191	12	-	27260156	G402	viability	AATAACTTCTCAGATTCCGTTGG	POC1B	ENSG00000139323	-0.35644342331931844	[487]	[545,486,530,314]	-4	hSpCas9	negative selection	6961565
89491950	89491973	12	-	27260156	L33	viability	CCTTGTATCGACATACACACTGG	POC1B	ENSG00000139323	0.1545426896215849	[1533]	[1505,765,1080,1738]	3	hSpCas9	negative selection	7018566
89491950	89491973	12	+	27260156	L33	viability	CCAGTGTGTATGTCGATACAAGG	POC1B	ENSG00000139323	-0.13041863138286514	[931]	[751,366,581,834]	-3	hSpCas9	negative selection	7018567
89472235	89472258	12	-	27260156	L33	viability	ACTAATTGTGTCATGTAGTGAGG	POC1B	ENSG00000139323	0.08704018563415583	[201]	[175,118,124,193]	2	hSpCas9	negative selection	7082815
89472168	89472191	12	-	27260156	L33	viability	AATAACTTCTCAGATTCCGTTGG	POC1B	ENSG00000139323	0.12825860573276296	[487]	[559,239,309,493]	3	hSpCas9	negative selection	7082816
89491950	89491973	12	-	27260156	K562	viability	CCTTGTATCGACATACACACTGG	POC1B	ENSG00000139323	0.46263388856473964	[1533]	[2158,1629,2575,1218]	6	hSpCas9	negative selection	7139817
89491950	89491973	12	+	27260156	K562	viability	CCAGTGTGTATGTCGATACAAGG	POC1B	ENSG00000139323	-0.17838132756813418	[931]	[931,974,606,466]	-2	hSpCas9	negative selection	7139818
89472235	89472258	12	-	27260156	K562	viability	ACTAATTGTGTCATGTAGTGAGG	POC1B	ENSG00000139323	-0.3144489248299036	[201]	[182,121,90,177]	-4	hSpCas9	negative selection	7204066
89472168	89472191	12	-	27260156	K562	viability	AATAACTTCTCAGATTCCGTTGG	POC1B	ENSG00000139323	0.03157813727748549	[487]	[507,191,524,525]	0	hSpCas9	negative selection	7204067
89491950	89491973	12	-	27260156	HT29	viability	CCTTGTATCGACATACACACTGG	POC1B	ENSG00000139323	0.13755477594318277	[1533]	[2086,2210,2048,1880]	2	hSpCas9	negative selection	7261068
89491950	89491973	12	+	27260156	HT29	viability	CCAGTGTGTATGTCGATACAAGG	POC1B	ENSG00000139323	-0.19364419413857703	[931]	[1082,1134,1009,773]	-4	hSpCas9	negative selection	7261069
89472235	89472258	12	-	27260156	HT29	viability	ACTAATTGTGTCATGTAGTGAGG	POC1B	ENSG00000139323	-0.22478474125757053	[201]	[245,228,199,172]	-4	hSpCas9	negative selection	7325317
89472168	89472191	12	-	27260156	HT29	viability	AATAACTTCTCAGATTCCGTTGG	POC1B	ENSG00000139323	0.08319722895703427	[487]	[693,656,692,489]	1	hSpCas9	negative selection	7325318
89491950	89491973	12	-	27260156	MHHES1	viability	CCTTGTATCGACATACACACTGG	POC1B	ENSG00000139323	0.026788800803288826	[1533]	[1578,1987,2199,1336]	0	hSpCas9	negative selection	7382319
89491950	89491973	12	+	27260156	MHHES1	viability	CCAGTGTGTATGTCGATACAAGG	POC1B	ENSG00000139323	-0.22993000218748538	[931]	[984,819,1037,753]	-4	hSpCas9	negative selection	7382320
89472235	89472258	12	-	27260156	MHHES1	viability	ACTAATTGTGTCATGTAGTGAGG	POC1B	ENSG00000139323	-0.2972883335173526	[201]	[165,182,225,163]	-5	hSpCas9	negative selection	7446568
89472168	89472191	12	-	27260156	MHHES1	viability	AATAACTTCTCAGATTCCGTTGG	POC1B	ENSG00000139323	-0.11415673364539997	[487]	[550,611,488,406]	-2	hSpCas9	negative selection	7446569
89491950	89491973	12	-	27260156	MEWO	viability	CCTTGTATCGACATACACACTGG	POC1B	ENSG00000139323	0.08819032910708358	[1533]	[1938,1238,1479]	2	hSpCas9	negative selection	7503570
89491950	89491973	12	+	27260156	MEWO	viability	CCAGTGTGTATGTCGATACAAGG	POC1B	ENSG00000139323	-0.2579277653931885	[931]	[685,740,751]	-5	hSpCas9	negative selection	7503571
89472235	89472258	12	-	27260156	MEWO	viability	ACTAATTGTGTCATGTAGTGAGG	POC1B	ENSG00000139323	-0.2078176965974492	[201]	[197,63,235]	-4	hSpCas9	negative selection	7567819
89472168	89472191	12	-	27260156	MEWO	viability	AATAACTTCTCAGATTCCGTTGG	POC1B	ENSG00000139323	-0.22215648426702472	[487]	[462,385,338]	-5	hSpCas9	negative selection	7567820
89491950	89491973	12	-	27260156	LNCAPCLONEFGC	viability	CCTTGTATCGACATACACACTGG	POC1B	ENSG00000139323	0.15929600458290216	[1533]	[1443,1590,1607,1570]	2	hSpCas9	negative selection	7624821
89491950	89491973	12	+	27260156	LNCAPCLONEFGC	viability	CCAGTGTGTATGTCGATACAAGG	POC1B	ENSG00000139323	-0.3803737632574421	[931]	[513,626,850,635]	-5	hSpCas9	negative selection	7624822
89472235	89472258	12	-	27260156	LNCAPCLONEFGC	viability	ACTAATTGTGTCATGTAGTGAGG	POC1B	ENSG00000139323	-0.18543436589645146	[201]	[123,120,228,182]	-3	hSpCas9	negative selection	7689070
89472168	89472191	12	-	27260156	LNCAPCLONEFGC	viability	AATAACTTCTCAGATTCCGTTGG	POC1B	ENSG00000139323	-0.22133016894449367	[487]	[363,371,363,414]	-4	hSpCas9	negative selection	7689071
89491950	89491973	12	-	27260156	PANC0327	viability	CCTTGTATCGACATACACACTGG	POC1B	ENSG00000139323	0.3633403775499311	[1533]	[1822,2131,1185,1825]	5	hSpCas9	negative selection	7746072
89491950	89491973	12	+	27260156	PANC0327	viability	CCAGTGTGTATGTCGATACAAGG	POC1B	ENSG00000139323	-0.04076632129909308	[931]	[1045,360,809,1078]	0	hSpCas9	negative selection	7746073
89472235	89472258	12	-	27260156	PANC0327	viability	ACTAATTGTGTCATGTAGTGAGG	POC1B	ENSG00000139323	-0.43039540064175674	[201]	[197,115,76,148]	-6	hSpCas9	negative selection	7810321
89472168	89472191	12	-	27260156	PANC0327	viability	AATAACTTCTCAGATTCCGTTGG	POC1B	ENSG00000139323	-0.8814574038941356	[487]	[234,304,152,238]	-8	hSpCas9	negative selection	7810322
89491950	89491973	12	-	27260156	NCIH2009	viability	CCTTGTATCGACATACACACTGG	POC1B	ENSG00000139323	0.2687704812092737	[1533]	[3016,2359,2454]	3	hSpCas9	negative selection	7867323
89491950	89491973	12	+	27260156	NCIH2009	viability	CCAGTGTGTATGTCGATACAAGG	POC1B	ENSG00000139323	-0.17606316365498975	[931]	[1410,1305,786]	-2	hSpCas9	negative selection	7867324
89472235	89472258	12	-	27260156	NCIH2009	viability	ACTAATTGTGTCATGTAGTGAGG	POC1B	ENSG00000139323	-0.037500501948506626	[201]	[265,258,297]	0	hSpCas9	negative selection	7931572
89472168	89472191	12	-	27260156	NCIH2009	viability	AATAACTTCTCAGATTCCGTTGG	POC1B	ENSG00000139323	-0.3679640284076505	[487]	[489,444,642]	-5	hSpCas9	negative selection	7931573
89491950	89491973	12	-	27260156	NCIH1373	viability	CCTTGTATCGACATACACACTGG	POC1B	ENSG00000139323	0.5385244677522694	[1533]	[3598,2117,2322,559]	5	hSpCas9	negative selection	7988574
89491950	89491973	12	+	27260156	NCIH1373	viability	CCAGTGTGTATGTCGATACAAGG	POC1B	ENSG00000139323	-0.04941630559948362	[931]	[1166,850,1025,270]	0	hSpCas9	negative selection	7988575
89472235	89472258	12	-	27260156	NCIH1373	viability	ACTAATTGTGTCATGTAGTGAGG	POC1B	ENSG00000139323	-0.5305635981803702	[201]	[124,104,252,36]	-5	hSpCas9	negative selection	8052823
89472168	89472191	12	-	27260156	NCIH1373	viability	AATAACTTCTCAGATTCCGTTGG	POC1B	ENSG00000139323	-0.46690896930732606	[487]	[623,224,498,72]	-5	hSpCas9	negative selection	8052824
89491950	89491973	12	-	27260156	PATU8902	viability	CCTTGTATCGACATACACACTGG	POC1B	ENSG00000139323	0.21134255080423814	[1533]	[2668,2347,2197,2761]	2	hSpCas9	negative selection	8109825
89491950	89491973	12	+	27260156	PATU8902	viability	CCAGTGTGTATGTCGATACAAGG	POC1B	ENSG00000139323	-0.2888446828350383	[931]	[1134,957,1224,854]	-3	hSpCas9	negative selection	8109826
89472235	89472258	12	-	27260156	PATU8902	viability	ACTAATTGTGTCATGTAGTGAGG	POC1B	ENSG00000139323	0.10829942702724349	[201]	[378,155,27,773]	1	hSpCas9	negative selection	8174074
89472168	89472191	12	-	27260156	PATU8902	viability	AATAACTTCTCAGATTCCGTTGG	POC1B	ENSG00000139323	-0.2445329840652929	[487]	[517,454,567,774]	-2	hSpCas9	negative selection	8174075
89491950	89491973	12	-	27260156	PANC1	viability	CCTTGTATCGACATACACACTGG	POC1B	ENSG00000139323	-0.3128064521522125	[1533]	[970,1303,1164,869]	-5	hSpCas9	negative selection	8231076
89491950	89491973	12	+	27260156	PANC1	viability	CCAGTGTGTATGTCGATACAAGG	POC1B	ENSG00000139323	-0.2891283283223707	[931]	[656,712,748,524]	-4	hSpCas9	negative selection	8231077
89472235	89472258	12	-	27260156	PANC1	viability	ACTAATTGTGTCATGTAGTGAGG	POC1B	ENSG00000139323	0.3262388241261309	[201]	[150,207,193,298]	5	hSpCas9	negative selection	8295325
89472168	89472191	12	-	27260156	PANC1	viability	AATAACTTCTCAGATTCCGTTGG	POC1B	ENSG00000139323	-0.049915649935204	[487]	[317,586,456,306]	-1	hSpCas9	negative selection	8295326
89491950	89491973	12	-	27260156	PANC0813	viability	CCTTGTATCGACATACACACTGG	POC1B	ENSG00000139323	-0.010369772612435657	[1533]	[2210,1740,1596,1649]	0	hSpCas9	negative selection	8352327
89491950	89491973	12	+	27260156	PANC0813	viability	CCAGTGTGTATGTCGATACAAGG	POC1B	ENSG00000139323	-0.4338705063093268	[931]	[901,747,723,870]	-6	hSpCas9	negative selection	8352328
89472235	89472258	12	-	27260156	PANC0813	viability	ACTAATTGTGTCATGTAGTGAGG	POC1B	ENSG00000139323	-0.48296775308368933	[201]	[348,84,158,105]	-6	hSpCas9	negative selection	8416576
89472168	89472191	12	-	27260156	PANC0813	viability	AATAACTTCTCAGATTCCGTTGG	POC1B	ENSG00000139323	-0.35076541786414944	[487]	[329,390,786,288]	-5	hSpCas9	negative selection	8416577
89491950	89491973	12	-	27260156	RDES	viability	CCTTGTATCGACATACACACTGG	POC1B	ENSG00000139323	-0.009873447186478312	[1533]	[1543,1507,1812,2232]	0	hSpCas9	negative selection	8473578
89491950	89491973	12	+	27260156	RDES	viability	CCAGTGTGTATGTCGATACAAGG	POC1B	ENSG00000139323	-0.7408192450629062	[931]	[537,583,708,763]	-8	hSpCas9	negative selection	8473579
89472235	89472258	12	-	27260156	RDES	viability	ACTAATTGTGTCATGTAGTGAGG	POC1B	ENSG00000139323	-0.1893803993747436	[201]	[148,128,243,326]	-3	hSpCas9	negative selection	8537827
89472168	89472191	12	-	27260156	RDES	viability	AATAACTTCTCAGATTCCGTTGG	POC1B	ENSG00000139323	-0.37218889985618325	[487]	[330,431,487,505]	-6	hSpCas9	negative selection	8537828
89491950	89491973	12	-	27260156	PC3	viability	CCTTGTATCGACATACACACTGG	POC1B	ENSG00000139323	0.07496898121156526	[1533]	[941,1818,2457,1687]	1	hSpCas9	negative selection	8594829
89491950	89491973	12	+	27260156	PC3	viability	CCAGTGTGTATGTCGATACAAGG	POC1B	ENSG00000139323	-0.3185580252940293	[931]	[437,681,1322,835]	-6	hSpCas9	negative selection	8594830
89472235	89472258	12	-	27260156	PC3	viability	ACTAATTGTGTCATGTAGTGAGG	POC1B	ENSG00000139323	-0.36617505234342884	[201]	[80,137,196,249]	-7	hSpCas9	negative selection	8659078
89472168	89472191	12	-	27260156	PC3	viability	AATAACTTCTCAGATTCCGTTGG	POC1B	ENSG00000139323	0.18654281716521998	[487]	[387,598,662,618]	4	hSpCas9	negative selection	8659079
89491950	89491973	12	-	27260156	PATU8988T	viability	CCTTGTATCGACATACACACTGG	POC1B	ENSG00000139323	-0.13989190211742764	[1533]	[1661,1226,1312,1152]	-2	hSpCas9	negative selection	8716080
89491950	89491973	12	+	27260156	PATU8988T	viability	CCAGTGTGTATGTCGATACAAGG	POC1B	ENSG00000139323	-0.40786331710478574	[931]	[803,491,790,602]	-6	hSpCas9	negative selection	8716081
89472235	89472258	12	-	27260156	PATU8988T	viability	ACTAATTGTGTCATGTAGTGAGG	POC1B	ENSG00000139323	-0.4956511537733319	[201]	[102,139,87,230]	-7	hSpCas9	negative selection	8780329
89472168	89472191	12	-	27260156	PATU8988T	viability	AATAACTTCTCAGATTCCGTTGG	POC1B	ENSG00000139323	-0.5427411117509325	[487]	[247,251,316,483]	-7	hSpCas9	negative selection	8780330
89491950	89491973	12	-	27260156	T47D	viability	CCTTGTATCGACATACACACTGG	POC1B	ENSG00000139323	0.13033632873864942	[1533]	[1984,1755,1941,2164]	2	hSpCas9	negative selection	8837331
89491950	89491973	12	+	27260156	T47D	viability	CCAGTGTGTATGTCGATACAAGG	POC1B	ENSG00000139323	-0.19323781279749797	[931]	[941,954,844,1060]	-4	hSpCas9	negative selection	8837332
89472235	89472258	12	-	27260156	T47D	viability	ACTAATTGTGTCATGTAGTGAGG	POC1B	ENSG00000139323	-0.3289758402318146	[201]	[186,190,204,164]	-6	hSpCas9	negative selection	8901580
89472168	89472191	12	-	27260156	T47D	viability	AATAACTTCTCAGATTCCGTTGG	POC1B	ENSG00000139323	-0.09786666052976836	[487]	[532,403,557,643]	-2	hSpCas9	negative selection	8901581
89491950	89491973	12	-	27260156	SU8686	viability	CCTTGTATCGACATACACACTGG	POC1B	ENSG00000139323	0.023371629686855355	[1533]	[1460,1377,1424,2010]	0	hSpCas9	negative selection	8958582
89491950	89491973	12	+	27260156	SU8686	viability	CCAGTGTGTATGTCGATACAAGG	POC1B	ENSG00000139323	-0.6055987951480125	[931]	[540,596,526,796]	-7	hSpCas9	negative selection	8958583
89472235	89472258	12	-	27260156	SU8686	viability	ACTAATTGTGTCATGTAGTGAGG	POC1B	ENSG00000139323	-0.5122234939905856	[201]	[168,154,70,161]	-7	hSpCas9	negative selection	9022831
89472168	89472191	12	-	27260156	SU8686	viability	AATAACTTCTCAGATTCCGTTGG	POC1B	ENSG00000139323	-0.35542543525691866	[487]	[404,338,353,419]	-5	hSpCas9	negative selection	9022832
89491950	89491973	12	-	27260156	SKES1	viability	CCTTGTATCGACATACACACTGG	POC1B	ENSG00000139323	-0.09554643669230756	[1533]	[1638,1644,1329,1184]	-2	hSpCas9	negative selection	9079833
89491950	89491973	12	+	27260156	SKES1	viability	CCAGTGTGTATGTCGATACAAGG	POC1B	ENSG00000139323	-0.4132317037599357	[931]	[700,856,678,581]	-7	hSpCas9	negative selection	9079834
89472235	89472258	12	-	27260156	SKES1	viability	ACTAATTGTGTCATGTAGTGAGG	POC1B	ENSG00000139323	-0.44709453988657466	[201]	[142,135,166,141]	-7	hSpCas9	negative selection	9144082
89472168	89472191	12	-	27260156	SKES1	viability	AATAACTTCTCAGATTCCGTTGG	POC1B	ENSG00000139323	-0.15283194377456666	[487]	[497,426,386,441]	-3	hSpCas9	negative selection	9144083
89491950	89491973	12	-	27260156	TOV112D	viability	CCTTGTATCGACATACACACTGG	POC1B	ENSG00000139323	0.1032314190098742	[1533]	[1808,1788,1429,1618]	2	hSpCas9	negative selection	9201084
89491950	89491973	12	+	27260156	TOV112D	viability	CCAGTGTGTATGTCGATACAAGG	POC1B	ENSG00000139323	-0.034110938925691836	[931]	[1179,1063,798,668]	0	hSpCas9	negative selection	9201085
89472235	89472258	12	-	27260156	TOV112D	viability	ACTAATTGTGTCATGTAGTGAGG	POC1B	ENSG00000139323	-0.3253724490823089	[201]	[180,93,134,218]	-6	hSpCas9	negative selection	9265333
89472168	89472191	12	-	27260156	TOV112D	viability	AATAACTTCTCAGATTCCGTTGG	POC1B	ENSG00000139323	0.38954189701883085	[487]	[801,623,807,343]	7	hSpCas9	negative selection	9265334
89491950	89491973	12	-	27260156	TC71	viability	CCTTGTATCGACATACACACTGG	POC1B	ENSG00000139323	-0.0009673791438506996	[1533]	[1585,1610,1673,1705]	0	hSpCas9	negative selection	9322335
89491950	89491973	12	+	27260156	TC71	viability	CCAGTGTGTATGTCGATACAAGG	POC1B	ENSG00000139323	-0.2920653233278009	[931]	[750,843,822,848]	-7	hSpCas9	negative selection	9322336
89472235	89472258	12	-	27260156	TC71	viability	ACTAATTGTGTCATGTAGTGAGG	POC1B	ENSG00000139323	0.008113161893613219	[201]	[267,151,195,256]	0	hSpCas9	negative selection	9386584
89472168	89472191	12	-	27260156	TC71	viability	AATAACTTCTCAGATTCCGTTGG	POC1B	ENSG00000139323	0.05624637236200813	[487]	[506,547,519,605]	1	hSpCas9	negative selection	9386585
89491950	89491973	12	-	27260156	TC32	viability	CCTTGTATCGACATACACACTGG	POC1B	ENSG00000139323	0.18924784828621544	[1533]	[1365,1312,1964,2072]	3	hSpCas9	negative selection	9443586
89491950	89491973	12	+	27260156	TC32	viability	CCAGTGTGTATGTCGATACAAGG	POC1B	ENSG00000139323	-0.2531222726623784	[931]	[675,587,924,805]	-4	hSpCas9	negative selection	9443587
89472235	89472258	12	-	27260156	TC32	viability	ACTAATTGTGTCATGTAGTGAGG	POC1B	ENSG00000139323	-0.20229618426780438	[201]	[106,125,185,262]	-4	hSpCas9	negative selection	9507835
89472168	89472191	12	-	27260156	TC32	viability	AATAACTTCTCAGATTCCGTTGG	POC1B	ENSG00000139323	-0.34070332536746234	[487]	[361,211,633,321]	-6	hSpCas9	negative selection	9507836
89425342	89425365	12	-	27869803	HPAFII	viability after 27 days	GGTAGGACTCTGCCAGACAAGGG	POC1B	ENSG00000139323	-1.3061383846335346	[61]	[22,4,NaN]	-7	hSpCas9	negative selection	9548796
89467630	89467653	12	-	27869803	HPAFII	viability after 27 days	GGAGAGCTATTTGCATCAGGAGG	POC1B	ENSG00000139323	-2.105586409559496	[63]	[15,0,NaN]	-8	hSpCas9	negative selection	9548797
89470441	89470464	12	+	27869803	HPAFII	viability after 27 days	TGAGATAGTTACCCGAAGGATGG	POC1B	ENSG00000139323	1.0227376874160437	[311]	[401,275,NaN]	8	hSpCas9	negative selection	9548798
89471676	89471699	12	-	27869803	HPAFII	viability after 27 days	GGTACATGCATAGCTTCAGCAGG	POC1B	ENSG00000139323	0.8571911264843057	[41]	[45,34,NaN]	7	hSpCas9	negative selection	9548799
89491950	89491973	12	-	27869803	HPAFII	viability after 27 days	CCTTGTATCGACATACACACTGG	POC1B	ENSG00000139323	-0.358519561376032	[563]	[299,173,NaN]	-3	hSpCas9	negative selection	9548802
89425342	89425365	12	-	27869803	HPAFII	viability after 15 days	GGTAGGACTCTGCCAGACAAGGG	POC1B	ENSG00000139323	0.06318901795249521	[61]	[68,69,NaN]	0	hSpCas9	negative selection	9631245
89467630	89467653	12	-	27869803	HPAFII	viability after 15 days	GGAGAGCTATTTGCATCAGGAGG	POC1B	ENSG00000139323	-0.36866644692169404	[63]	[109,17,NaN]	-4	hSpCas9	negative selection	9631246
89470441	89470464	12	+	27869803	HPAFII	viability after 15 days	TGAGATAGTTACCCGAAGGATGG	POC1B	ENSG00000139323	0.36881139161557897	[311]	[670,284,NaN]	4	hSpCas9	negative selection	9631247
89471676	89471699	12	-	27869803	HPAFII	viability after 15 days	GGTACATGCATAGCTTCAGCAGG	POC1B	ENSG00000139323	0.43105700821640136	[41]	[132,15,NaN]	5	hSpCas9	negative selection	9631248
89491950	89491973	12	-	27869803	HPAFII	viability after 15 days	CCTTGTATCGACATACACACTGG	POC1B	ENSG00000139323	-0.38075139297408944	[563]	[578,394,NaN]	-4	hSpCas9	negative selection	9631251
89425342	89425365	12	-	27869803	ASPC1	viability after 36 days	GGTAGGACTCTGCCAGACAAGGG	POC1B	ENSG00000139323	0.0237519744751733	[144]	[6,72,64]	0	hSpCas9	negative selection	9713694
89467630	89467653	12	-	27869803	ASPC1	viability after 36 days	GGAGAGCTATTTGCATCAGGAGG	POC1B	ENSG00000139323	-0.5690195897294366	[261]	[49,13,106]	-5	hSpCas9	negative selection	9713695
89470441	89470464	12	+	27869803	ASPC1	viability after 36 days	TGAGATAGTTACCCGAAGGATGG	POC1B	ENSG00000139323	0.4370628052064327	[696]	[672,264,135]	4	hSpCas9	negative selection	9713696
89471676	89471699	12	-	27869803	ASPC1	viability after 36 days	GGTACATGCATAGCTTCAGCAGG	POC1B	ENSG00000139323	0.8358987372478133	[103]	[120,42,41]	7	hSpCas9	negative selection	9713697
89491950	89491973	12	-	27869803	ASPC1	viability after 36 days	CCTTGTATCGACATACACACTGG	POC1B	ENSG00000139323	0.07278621433447774	[1194]	[440,388,471]	0	hSpCas9	negative selection	9713700
89425342	89425365	12	-	27869803	PATU8988S	viability after 35 days	GGTAGGACTCTGCCAGACAAGGG	POC1B	ENSG00000139323	-0.7000050704070009	[251]	[51,72,NaN]	-6	hSpCas9	negative selection	9796143
89467630	89467653	12	-	27869803	PATU8988S	viability after 35 days	GGAGAGCTATTTGCATCAGGAGG	POC1B	ENSG00000139323	0.2339022821535155	[261]	[164,82,NaN]	2	hSpCas9	negative selection	9796144
89470441	89470464	12	+	27869803	PATU8988S	viability after 35 days	TGAGATAGTTACCCGAAGGATGG	POC1B	ENSG00000139323	-0.29057998967725207	[556]	[142,223,NaN]	-3	hSpCas9	negative selection	9796145
89471676	89471699	12	-	27869803	PATU8988S	viability after 35 days	GGTACATGCATAGCTTCAGCAGG	POC1B	ENSG00000139323	1.2864567495167654	[52]	[81,21,NaN]	9	hSpCas9	negative selection	9796146
89491950	89491973	12	-	27869803	PATU8988S	viability after 35 days	CCTTGTATCGACATACACACTGG	POC1B	ENSG00000139323	0.17325548093922127	[1048]	[429,522,NaN]	2	hSpCas9	negative selection	9796149
89425342	89425365	12	-	27869803	PATU8988S	viability after 31 days	GGTAGGACTCTGCCAGACAAGGG	POC1B	ENSG00000139323	-0.7497132478767843	[251]	[57,61,NaN]	-7	hSpCas9	negative selection	9878592
89467630	89467653	12	-	27869803	PATU8988S	viability after 31 days	GGAGAGCTATTTGCATCAGGAGG	POC1B	ENSG00000139323	0.44394275730577926	[261]	[109,182,NaN]	5	hSpCas9	negative selection	9878593
89470441	89470464	12	+	27869803	PATU8988S	viability after 31 days	TGAGATAGTTACCCGAAGGATGG	POC1B	ENSG00000139323	-0.4466593281215526	[556]	[180,139,NaN]	-5	hSpCas9	negative selection	9878594
89471676	89471699	12	-	27869803	PATU8988S	viability after 31 days	GGTACATGCATAGCTTCAGCAGG	POC1B	ENSG00000139323	0.75560144951507	[52]	[36,33,NaN]	8	hSpCas9	negative selection	9878595
89491950	89491973	12	-	27869803	PATU8988S	viability after 31 days	CCTTGTATCGACATACACACTGG	POC1B	ENSG00000139323	0.08863854820839889	[1048]	[380,525,NaN]	1	hSpCas9	negative selection	9878598
89425342	89425365	12	-	27869803	HPAFII	viability after 35 days	GGTAGGACTCTGCCAGACAAGGG	POC1B	ENSG00000139323	-4.972107757390201	[61]	[0,0,NaN]	-9	hSpCas9	negative selection	9961041
89467630	89467653	12	-	27869803	HPAFII	viability after 35 days	GGAGAGCTATTTGCATCAGGAGG	POC1B	ENSG00000139323	-1.944944787245341	[63]	[14,0,NaN]	-7	hSpCas9	negative selection	9961042
89470441	89470464	12	+	27869803	HPAFII	viability after 35 days	TGAGATAGTTACCCGAAGGATGG	POC1B	ENSG00000139323	1.2588382419931463	[311]	[448,297,NaN]	8	hSpCas9	negative selection	9961043
89471676	89471699	12	-	27869803	HPAFII	viability after 35 days	GGTACATGCATAGCTTCAGCAGG	POC1B	ENSG00000139323	0.6674734872111587	[41]	[45,19,NaN]	4	hSpCas9	negative selection	9961044
89491950	89491973	12	-	27869803	HPAFII	viability after 35 days	CCTTGTATCGACATACACACTGG	POC1B	ENSG00000139323	-0.41671544807143646	[563]	[235,188,NaN]	-3	hSpCas9	negative selection	9961047
89425342	89425365	12	-	27869803	HPAFII	viability after 31 days	GGTAGGACTCTGCCAGACAAGGG	POC1B	ENSG00000139323	-2.161319888939677	[61]	[13,0,NaN]	-8	hSpCas9	negative selection	10043490
89467630	89467653	12	-	27869803	HPAFII	viability after 31 days	GGAGAGCTATTTGCATCAGGAGG	POC1B	ENSG00000139323	-2.531040226533618	[63]	[10,0,NaN]	-8	hSpCas9	negative selection	10043491
89470441	89470464	12	+	27869803	HPAFII	viability after 31 days	TGAGATAGTTACCCGAAGGATGG	POC1B	ENSG00000139323	1.1155720102954112	[311]	[488,259,NaN]	8	hSpCas9	negative selection	10043492
89471676	89471699	12	-	27869803	HPAFII	viability after 31 days	GGTACATGCATAGCTTCAGCAGG	POC1B	ENSG00000139323	-0.548038536856633	[41]	[29,0,NaN]	-4	hSpCas9	negative selection	10043493
89491950	89491973	12	-	27869803	HPAFII	viability after 31 days	CCTTGTATCGACATACACACTGG	POC1B	ENSG00000139323	-0.25027800284817425	[563]	[290,238,NaN]	-2	hSpCas9	negative selection	10043496
89497230	89497253	12	+	28162770	P31FUJ	viability	ATGTGGAGAAAACTGCACGCTGG	POC1B	ENSG00000139323	0.9631180055608782	[109]	[251]	9	hSpCas9	negative selection	10213808
89466790	89466813	12	-	28162770	P31FUJ	viability	AAGAACACCACATCCCCATGAGG	POC1B	ENSG00000139323	0.1554503137764125	[896]	[1173]	1	hSpCas9	negative selection	10213809
89491967	89491990	12	+	28162770	P31FUJ	viability	ACAAGGAATACAGGAAGCGCTGG	POC1B	ENSG00000139323	0.44915662278241875	[138]	[222]	5	hSpCas9	negative selection	10213810
89425327	89425350	12	-	28162770	P31FUJ	viability	GACAAGGGTGAAGAGGCCTGTGG	POC1B	ENSG00000139323	-0.05736019800450065	[115]	[130]	0	hSpCas9	negative selection	10213811
89470482	89470505	12	-	28162770	P31FUJ	viability	TACAAATCAGTTCACAGCGGTGG	POC1B	ENSG00000139323	0.18111475497054996	[321]	[428]	2	hSpCas9	negative selection	10213812
89470441	89470464	12	+	28162770	P31FUJ	viability	TGAGATAGTTACCCGAAGGATGG	POC1B	ENSG00000139323	-1.005391708311306	[40]	[23]	-6	hSpCas9	negative selection	10213813
89467630	89467653	12	-	28162770	P31FUJ	viability	GGAGAGCTATTTGCATCAGGAGG	POC1B	ENSG00000139323	-0.4449554412459886	[116]	[100]	-4	hSpCas9	negative selection	10213814
89466813	89466836	12	+	28162770	P31FUJ	viability	GGGTAGATATCAAGAAGATGTGG	POC1B	ENSG00000139323	0.16299349850398492	[433]	[570]	1	hSpCas9	negative selection	10213815
89492056	89492079	12	+	28162770	P31FUJ	viability	GAAAAGTCTACACTTCGAACTGG	POC1B	ENSG00000139323	-0.5421302625221074	[113]	[91]	-4	hSpCas9	negative selection	10213816
89471682	89471705	12	+	28162770	P31FUJ	viability	GAAGCTATGCATGTACCACTAGG	POC1B	ENSG00000139323	0.2772318088002119	[763]	[1087]	3	hSpCas9	negative selection	10213817
89497230	89497253	12	+	28162770	TF1	viability	ATGTGGAGAAAACTGCACGCTGG	POC1B	ENSG00000139323	NaN	[NaN]	[162]	1	hSpCas9	negative selection	10383174
89466790	89466813	12	-	28162770	TF1	viability	AAGAACACCACATCCCCATGAGG	POC1B	ENSG00000139323	NaN	[NaN]	[1189]	1	hSpCas9	negative selection	10383175
89491967	89491990	12	+	28162770	TF1	viability	ACAAGGAATACAGGAAGCGCTGG	POC1B	ENSG00000139323	NaN	[NaN]	[172]	1	hSpCas9	negative selection	10383176
89425327	89425350	12	-	28162770	TF1	viability	GACAAGGGTGAAGAGGCCTGTGG	POC1B	ENSG00000139323	NaN	[NaN]	[208]	1	hSpCas9	negative selection	10383177
89470482	89470505	12	-	28162770	TF1	viability	TACAAATCAGTTCACAGCGGTGG	POC1B	ENSG00000139323	NaN	[NaN]	[350]	1	hSpCas9	negative selection	10383178
89470441	89470464	12	+	28162770	TF1	viability	TGAGATAGTTACCCGAAGGATGG	POC1B	ENSG00000139323	NaN	[NaN]	[11]	1	hSpCas9	negative selection	10383179
89467630	89467653	12	-	28162770	TF1	viability	GGAGAGCTATTTGCATCAGGAGG	POC1B	ENSG00000139323	NaN	[NaN]	[173]	1	hSpCas9	negative selection	10383180
89466813	89466836	12	+	28162770	TF1	viability	GGGTAGATATCAAGAAGATGTGG	POC1B	ENSG00000139323	NaN	[NaN]	[232]	1	hSpCas9	negative selection	10383181
89492056	89492079	12	+	28162770	TF1	viability	GAAAAGTCTACACTTCGAACTGG	POC1B	ENSG00000139323	NaN	[NaN]	[108]	1	hSpCas9	negative selection	10383182
89471682	89471705	12	+	28162770	TF1	viability	GAAGCTATGCATGTACCACTAGG	POC1B	ENSG00000139323	NaN	[NaN]	[885]	1	hSpCas9	negative selection	10383183
89497230	89497253	12	+	28162770	SKM1	viability	ATGTGGAGAAAACTGCACGCTGG	POC1B	ENSG00000139323	-0.9970884045800966	[34]	[30]	-6	hSpCas9	negative selection	10552540
89466790	89466813	12	-	28162770	SKM1	viability	AAGAACACCACATCCCCATGAGG	POC1B	ENSG00000139323	-0.27451390271951226	[220]	[322]	-2	hSpCas9	negative selection	10552541
89491967	89491990	12	+	28162770	SKM1	viability	ACAAGGAATACAGGAAGCGCTGG	POC1B	ENSG00000139323	-0.22535739225321383	[40]	[61]	-2	hSpCas9	negative selection	10552542
89425327	89425350	12	-	28162770	SKM1	viability	GACAAGGGTGAAGAGGCCTGTGG	POC1B	ENSG00000139323	-0.6155508205545791	[38]	[44]	-5	hSpCas9	negative selection	10552543
89470482	89470505	12	-	28162770	SKM1	viability	TACAAATCAGTTCACAGCGGTGG	POC1B	ENSG00000139323	-0.777147462237745	[94]	[97]	-5	hSpCas9	negative selection	10552544
89470441	89470464	12	+	28162770	SKM1	viability	TGAGATAGTTACCCGAAGGATGG	POC1B	ENSG00000139323	-2.2005133212757357	[12]	[4]	-8	hSpCas9	negative selection	10552545
89467630	89467653	12	-	28162770	SKM1	viability	GGAGAGCTATTTGCATCAGGAGG	POC1B	ENSG00000139323	1.379632163147645	[24]	[114]	9	hSpCas9	negative selection	10552546
89466813	89466836	12	+	28162770	SKM1	viability	GGGTAGATATCAAGAAGATGTGG	POC1B	ENSG00000139323	-0.9842731269208826	[93]	[83]	-6	hSpCas9	negative selection	10552547
89492056	89492079	12	+	28162770	SKM1	viability	GAAAAGTCTACACTTCGAACTGG	POC1B	ENSG00000139323	-0.6887351671585413	[30]	[33]	-5	hSpCas9	negative selection	10552548
89471682	89471705	12	+	28162770	SKM1	viability	GAAGCTATGCATGTACCACTAGG	POC1B	ENSG00000139323	-1.4949606797409907	[168]	[105]	-7	hSpCas9	negative selection	10552549
89497230	89497253	12	+	28162770	SKM1	viability	ATGTGGAGAAAACTGCACGCTGG	POC1B	ENSG00000139323	-0.9970884045800966	[34]	[30]	-6	hSpCas9	negative selection	10721906
89466790	89466813	12	-	28162770	SKM1	viability	AAGAACACCACATCCCCATGAGG	POC1B	ENSG00000139323	-0.27451390271951226	[220]	[322]	-2	hSpCas9	negative selection	10721907
89491967	89491990	12	+	28162770	SKM1	viability	ACAAGGAATACAGGAAGCGCTGG	POC1B	ENSG00000139323	-0.22535739225321383	[40]	[61]	-2	hSpCas9	negative selection	10721908
89425327	89425350	12	-	28162770	SKM1	viability	GACAAGGGTGAAGAGGCCTGTGG	POC1B	ENSG00000139323	-0.6155508205545791	[38]	[44]	-5	hSpCas9	negative selection	10721909
89470482	89470505	12	-	28162770	SKM1	viability	TACAAATCAGTTCACAGCGGTGG	POC1B	ENSG00000139323	-0.777147462237745	[94]	[97]	-5	hSpCas9	negative selection	10721910
89470441	89470464	12	+	28162770	SKM1	viability	TGAGATAGTTACCCGAAGGATGG	POC1B	ENSG00000139323	-2.2005133212757357	[12]	[4]	-8	hSpCas9	negative selection	10721911
89467630	89467653	12	-	28162770	SKM1	viability	GGAGAGCTATTTGCATCAGGAGG	POC1B	ENSG00000139323	1.379632163147645	[24]	[114]	9	hSpCas9	negative selection	10721912
89466813	89466836	12	+	28162770	SKM1	viability	GGGTAGATATCAAGAAGATGTGG	POC1B	ENSG00000139323	-0.9842731269208826	[93]	[83]	-6	hSpCas9	negative selection	10721913
89492056	89492079	12	+	28162770	SKM1	viability	GAAAAGTCTACACTTCGAACTGG	POC1B	ENSG00000139323	-0.6887351671585413	[30]	[33]	-5	hSpCas9	negative selection	10721914
89471682	89471705	12	+	28162770	SKM1	viability	GAAGCTATGCATGTACCACTAGG	POC1B	ENSG00000139323	-1.4949606797409907	[168]	[105]	-7	hSpCas9	negative selection	10721915
89497230	89497253	12	+	28162770	PL21	viability	ATGTGGAGAAAACTGCACGCTGG	POC1B	ENSG00000139323	0.35912913825047693	[205]	[114]	3	hSpCas9	negative selection	10891272
89466790	89466813	12	-	28162770	PL21	viability	AAGAACACCACATCCCCATGAGG	POC1B	ENSG00000139323	0.24370862942671945	[847]	[436]	2	hSpCas9	negative selection	10891273
89491967	89491990	12	+	28162770	PL21	viability	ACAAGGAATACAGGAAGCGCTGG	POC1B	ENSG00000139323	0.67441631714284	[166]	[115]	6	hSpCas9	negative selection	10891274
89425327	89425350	12	-	28162770	PL21	viability	GACAAGGGTGAAGAGGCCTGTGG	POC1B	ENSG00000139323	0.8216279912355902	[116]	[89]	7	hSpCas9	negative selection	10891275
89470482	89470505	12	-	28162770	PL21	viability	TACAAATCAGTTCACAGCGGTGG	POC1B	ENSG00000139323	-0.1362465330917333	[350]	[138]	-1	hSpCas9	negative selection	10891276
89470441	89470464	12	+	28162770	PL21	viability	TGAGATAGTTACCCGAAGGATGG	POC1B	ENSG00000139323	0.22438716073599752	[58]	[29]	2	hSpCas9	negative selection	10891277
89467630	89467653	12	-	28162770	PL21	viability	GGAGAGCTATTTGCATCAGGAGG	POC1B	ENSG00000139323	-0.3458287546159726	[72]	[24]	-2	hSpCas9	negative selection	10891278
89466813	89466836	12	+	28162770	PL21	viability	GGGTAGATATCAAGAAGATGTGG	POC1B	ENSG00000139323	-0.7107529116766947	[360]	[95]	-5	hSpCas9	negative selection	10891279
89492056	89492079	12	+	28162770	PL21	viability	GAAAAGTCTACACTTCGAACTGG	POC1B	ENSG00000139323	0.4103573218796658	[101]	[58]	3	hSpCas9	negative selection	10891280
89471682	89471705	12	+	28162770	PL21	viability	GAAGCTATGCATGTACCACTAGG	POC1B	ENSG00000139323	0.23941960215113145	[470]	[241]	2	hSpCas9	negative selection	10891281
89497230	89497253	12	+	28162770	P31FUJ	viability	ATGTGGAGAAAACTGCACGCTGG	POC1B	ENSG00000139323	0.9631180055608782	[109]	[251]	9	hSpCas9	negative selection	11060638
89466790	89466813	12	-	28162770	P31FUJ	viability	AAGAACACCACATCCCCATGAGG	POC1B	ENSG00000139323	0.1554503137764125	[896]	[1173]	1	hSpCas9	negative selection	11060639
89491967	89491990	12	+	28162770	P31FUJ	viability	ACAAGGAATACAGGAAGCGCTGG	POC1B	ENSG00000139323	0.44915662278241875	[138]	[222]	5	hSpCas9	negative selection	11060640
89425327	89425350	12	-	28162770	P31FUJ	viability	GACAAGGGTGAAGAGGCCTGTGG	POC1B	ENSG00000139323	-0.05736019800450065	[115]	[130]	0	hSpCas9	negative selection	11060641
89470482	89470505	12	-	28162770	P31FUJ	viability	TACAAATCAGTTCACAGCGGTGG	POC1B	ENSG00000139323	0.18111475497054996	[321]	[428]	2	hSpCas9	negative selection	11060642
89470441	89470464	12	+	28162770	P31FUJ	viability	TGAGATAGTTACCCGAAGGATGG	POC1B	ENSG00000139323	-1.005391708311306	[40]	[23]	-6	hSpCas9	negative selection	11060643
89467630	89467653	12	-	28162770	P31FUJ	viability	GGAGAGCTATTTGCATCAGGAGG	POC1B	ENSG00000139323	-0.4449554412459886	[116]	[100]	-4	hSpCas9	negative selection	11060644
89466813	89466836	12	+	28162770	P31FUJ	viability	GGGTAGATATCAAGAAGATGTGG	POC1B	ENSG00000139323	0.16299349850398492	[433]	[570]	1	hSpCas9	negative selection	11060645
89492056	89492079	12	+	28162770	P31FUJ	viability	GAAAAGTCTACACTTCGAACTGG	POC1B	ENSG00000139323	-0.5421302625221074	[113]	[91]	-4	hSpCas9	negative selection	11060646
89471682	89471705	12	+	28162770	P31FUJ	viability	GAAGCTATGCATGTACCACTAGG	POC1B	ENSG00000139323	0.2772318088002119	[763]	[1087]	3	hSpCas9	negative selection	11060647
89497230	89497253	12	+	28162770	OCIAML5	viability	ATGTGGAGAAAACTGCACGCTGG	POC1B	ENSG00000139323	1.1118641744284814	[80]	[315]	8	hSpCas9	negative selection	11230004
89466790	89466813	12	-	28162770	OCIAML5	viability	AAGAACACCACATCCCCATGAGG	POC1B	ENSG00000139323	0.6963171312869321	[465]	[1362]	6	hSpCas9	negative selection	11230005
89491967	89491990	12	+	28162770	OCIAML5	viability	ACAAGGAATACAGGAAGCGCTGG	POC1B	ENSG00000139323	0.827674154609259	[53]	[172]	7	hSpCas9	negative selection	11230006
89425327	89425350	12	-	28162770	OCIAML5	viability	GACAAGGGTGAAGAGGCCTGTGG	POC1B	ENSG00000139323	-0.036029405706591744	[70]	[124]	0	hSpCas9	negative selection	11230007
89470482	89470505	12	-	28162770	OCIAML5	viability	TACAAATCAGTTCACAGCGGTGG	POC1B	ENSG00000139323	-0.01614249660962186	[199]	[356]	0	hSpCas9	negative selection	11230008
89470441	89470464	12	+	28162770	OCIAML5	viability	TGAGATAGTTACCCGAAGGATGG	POC1B	ENSG00000139323	0.3178584305783154	[15]	[35]	2	hSpCas9	negative selection	11230009
89467630	89467653	12	-	28162770	OCIAML5	viability	GGAGAGCTATTTGCATCAGGAGG	POC1B	ENSG00000139323	0.27666674325820595	[74]	[163]	2	hSpCas9	negative selection	11230010
89466813	89466836	12	+	28162770	OCIAML5	viability	GGGTAGATATCAAGAAGATGTGG	POC1B	ENSG00000139323	0.6517909617134319	[249]	[708]	6	hSpCas9	negative selection	11230011
89492056	89492079	12	+	28162770	OCIAML5	viability	GAAAAGTCTACACTTCGAACTGG	POC1B	ENSG00000139323	0.030576478497844284	[63]	[117]	0	hSpCas9	negative selection	11230012
89471682	89471705	12	+	28162770	OCIAML5	viability	GAAGCTATGCATGTACCACTAGG	POC1B	ENSG00000139323	0.56914340303745	[378]	[1014]	5	hSpCas9	negative selection	11230013
89497230	89497253	12	+	28162770	EOL1	viability	ATGTGGAGAAAACTGCACGCTGG	POC1B	ENSG00000139323	-0.10168377000264522	[443]	[217]	-1	hSpCas9	negative selection	11399370
89466790	89466813	12	-	28162770	EOL1	viability	AAGAACACCACATCCCCATGAGG	POC1B	ENSG00000139323	0.8096184199684797	[1096]	[1012]	7	hSpCas9	negative selection	11399371
89491967	89491990	12	+	28162770	EOL1	viability	ACAAGGAATACAGGAAGCGCTGG	POC1B	ENSG00000139323	-0.1646227381067112	[316]	[148]	-1	hSpCas9	negative selection	11399372
89425327	89425350	12	-	28162770	EOL1	viability	GACAAGGGTGAAGAGGCCTGTGG	POC1B	ENSG00000139323	0.3995925802136553	[258]	[179]	3	hSpCas9	negative selection	11399373
89470482	89470505	12	-	28162770	EOL1	viability	TACAAATCAGTTCACAGCGGTGG	POC1B	ENSG00000139323	0.645187750290292	[550]	[453]	6	hSpCas9	negative selection	11399374
89470441	89470464	12	+	28162770	EOL1	viability	TGAGATAGTTACCCGAAGGATGG	POC1B	ENSG00000139323	-2.534883847066763	[76]	[6]	-8	hSpCas9	negative selection	11399375
89467630	89467653	12	-	28162770	EOL1	viability	GGAGAGCTATTTGCATCAGGAGG	POC1B	ENSG00000139323	-0.16737471787050473	[161]	[75]	-1	hSpCas9	negative selection	11399376
89466813	89466836	12	+	28162770	EOL1	viability	GGGTAGATATCAAGAAGATGTGG	POC1B	ENSG00000139323	-0.3188578275143268	[437]	[184]	-2	hSpCas9	negative selection	11399377
89492056	89492079	12	+	28162770	EOL1	viability	GAAAAGTCTACACTTCGAACTGG	POC1B	ENSG00000139323	0.17185782511131187	[122]	[72]	1	hSpCas9	negative selection	11399378
89471682	89471705	12	+	28162770	EOL1	viability	GAAGCTATGCATGTACCACTAGG	POC1B	ENSG00000139323	0.49738939366503243	[756]	[562]	4	hSpCas9	negative selection	11399379
89497230	89497253	12	+	28162770	MOLM13	viability	ATGTGGAGAAAACTGCACGCTGG	POC1B	ENSG00000139323	0.8481614626627458	[251]	[327]	6	hSpCas9	negative selection	11568736
89466790	89466813	12	-	28162770	MOLM13	viability	AAGAACACCACATCCCCATGAGG	POC1B	ENSG00000139323	0.6046320761597506	[1206]	[1326]	4	hSpCas9	negative selection	11568737
89491967	89491990	12	+	28162770	MOLM13	viability	ACAAGGAATACAGGAAGCGCTGG	POC1B	ENSG00000139323	0.7527043034148417	[251]	[306]	6	hSpCas9	negative selection	11568738
89425327	89425350	12	-	28162770	MOLM13	viability	GACAAGGGTGAAGAGGCCTGTGG	POC1B	ENSG00000139323	-0.43614155992469894	[188]	[100]	-3	hSpCas9	negative selection	11568739
89470482	89470505	12	-	28162770	MOLM13	viability	TACAAATCAGTTCACAGCGGTGG	POC1B	ENSG00000139323	0.2466957097917566	[400]	[343]	1	hSpCas9	negative selection	11568740
89470441	89470464	12	+	28162770	MOLM13	viability	TGAGATAGTTACCCGAAGGATGG	POC1B	ENSG00000139323	0.8829268808234225	[47]	[63]	6	hSpCas9	negative selection	11568741
89467630	89467653	12	-	28162770	MOLM13	viability	GGAGAGCTATTTGCATCAGGAGG	POC1B	ENSG00000139323	-0.5502579651656806	[159]	[78]	-3	hSpCas9	negative selection	11568742
89466813	89466836	12	+	28162770	MOLM13	viability	GGGTAGATATCAAGAAGATGTGG	POC1B	ENSG00000139323	-0.266402078323302	[538]	[323]	-2	hSpCas9	negative selection	11568743
89492056	89492079	12	+	28162770	MOLM13	viability	GAAAAGTCTACACTTCGAACTGG	POC1B	ENSG00000139323	-3.555957360409789	[243]	[14]	-8	hSpCas9	negative selection	11568744
89471682	89471705	12	+	28162770	MOLM13	viability	GAAGCTATGCATGTACCACTAGG	POC1B	ENSG00000139323	0.13842761397180903	[959]	[763]	1	hSpCas9	negative selection	11568745
89497230	89497253	12	+	28162770	HEL	viability	ATGTGGAGAAAACTGCACGCTGG	POC1B	ENSG00000139323	1.2153176082656807	[194]	[289]	9	hSpCas9	negative selection	11738102
89466790	89466813	12	-	28162770	HEL	viability	AAGAACACCACATCCCCATGAGG	POC1B	ENSG00000139323	0.09370224960237672	[931]	[636]	0	hSpCas9	negative selection	11738103
89491967	89491990	12	+	28162770	HEL	viability	ACAAGGAATACAGGAAGCGCTGG	POC1B	ENSG00000139323	0.14483306554842396	[208]	[147]	1	hSpCas9	negative selection	11738104
89425327	89425350	12	-	28162770	HEL	viability	GACAAGGGTGAAGAGGCCTGTGG	POC1B	ENSG00000139323	-0.12102682150956434	[162]	[95]	-1	hSpCas9	negative selection	11738105
89470482	89470505	12	-	28162770	HEL	viability	TACAAATCAGTTCACAGCGGTGG	POC1B	ENSG00000139323	-0.11052857449494968	[444]	[263]	-1	hSpCas9	negative selection	11738106
89470441	89470464	12	+	28162770	HEL	viability	TGAGATAGTTACCCGAAGGATGG	POC1B	ENSG00000139323	-0.8906933680807172	[54]	[18]	-5	hSpCas9	negative selection	11738107
89467630	89467653	12	-	28162770	HEL	viability	GGAGAGCTATTTGCATCAGGAGG	POC1B	ENSG00000139323	-1.021840836784167	[148]	[46]	-6	hSpCas9	negative selection	11738108
89466813	89466836	12	+	28162770	HEL	viability	GGGTAGATATCAAGAAGATGTGG	POC1B	ENSG00000139323	-0.44569913266722694	[369]	[173]	-3	hSpCas9	negative selection	11738109
89492056	89492079	12	+	28162770	HEL	viability	GAAAAGTCTACACTTCGAACTGG	POC1B	ENSG00000139323	-0.7764864642419205	[229]	[85]	-5	hSpCas9	negative selection	11738110
89471682	89471705	12	+	28162770	HEL	viability	GAAGCTATGCATGTACCACTAGG	POC1B	ENSG00000139323	0.0494730275479911	[696]	[461]	0	hSpCas9	negative selection	11738111
89497230	89497253	12	+	28162770	MV411	viability	ATGTGGAGAAAACTGCACGCTGG	POC1B	ENSG00000139323	1.083137098534341	[143]	[256]	8	hSpCas9	negative selection	11907468
89466790	89466813	12	-	28162770	MV411	viability	AAGAACACCACATCCCCATGAGG	POC1B	ENSG00000139323	0.45683399301449557	[684]	[791]	4	hSpCas9	negative selection	11907469
89491967	89491990	12	+	28162770	MV411	viability	ACAAGGAATACAGGAAGCGCTGG	POC1B	ENSG00000139323	0.5795136010462205	[169]	[213]	5	hSpCas9	negative selection	11907470
89425327	89425350	12	-	28162770	MV411	viability	GACAAGGGTGAAGAGGCCTGTGG	POC1B	ENSG00000139323	-1.4872720694430628	[212]	[63]	-7	hSpCas9	negative selection	11907471
89470482	89470505	12	-	28162770	MV411	viability	TACAAATCAGTTCACAGCGGTGG	POC1B	ENSG00000139323	0.6474580144208958	[337]	[445]	6	hSpCas9	negative selection	11907472
89470441	89470464	12	+	28162770	MV411	viability	TGAGATAGTTACCCGAAGGATGG	POC1B	ENSG00000139323	0.16726720209879176	[36]	[34]	1	hSpCas9	negative selection	11907473
89467630	89467653	12	-	28162770	MV411	viability	GGAGAGCTATTTGCATCAGGAGG	POC1B	ENSG00000139323	0.5469978326416833	[103]	[127]	5	hSpCas9	negative selection	11907474
89466813	89466836	12	+	28162770	MV411	viability	GGGTAGATATCAAGAAGATGTGG	POC1B	ENSG00000139323	0.4017656971740692	[309]	[344]	3	hSpCas9	negative selection	11907475
89492056	89492079	12	+	28162770	MV411	viability	GAAAAGTCTACACTTCGAACTGG	POC1B	ENSG00000139323	-0.14302192577540274	[96]	[73]	-1	hSpCas9	negative selection	11907476
89471682	89471705	12	+	28162770	MV411	viability	GAAGCTATGCATGTACCACTAGG	POC1B	ENSG00000139323	0.32183297646773124	[547]	[576]	3	hSpCas9	negative selection	11907477
89497230	89497253	12	+	28162770	MONOMAC1	viability	ATGTGGAGAAAACTGCACGCTGG	POC1B	ENSG00000139323	0.28161675151526183	[121]	[169]	3	hSpCas9	negative selection	12076834
89466790	89466813	12	-	28162770	MONOMAC1	viability	AAGAACACCACATCCCCATGAGG	POC1B	ENSG00000139323	0.32387228255420375	[567]	[814]	3	hSpCas9	negative selection	12076835
89491967	89491990	12	+	28162770	MONOMAC1	viability	ACAAGGAATACAGGAAGCGCTGG	POC1B	ENSG00000139323	0.5034028710815385	[87]	[142]	5	hSpCas9	negative selection	12076836
89425327	89425350	12	-	28162770	MONOMAC1	viability	GACAAGGGTGAAGAGGCCTGTGG	POC1B	ENSG00000139323	0.03244499906321374	[86]	[101]	0	hSpCas9	negative selection	12076837
89470482	89470505	12	-	28162770	MONOMAC1	viability	TACAAATCAGTTCACAGCGGTGG	POC1B	ENSG00000139323	1.618604686183011	[247]	[872]	9	hSpCas9	negative selection	12076838
89470441	89470464	12	+	28162770	MONOMAC1	viability	TGAGATAGTTACCCGAAGGATGG	POC1B	ENSG00000139323	-0.027111845617241226	[23]	[26]	0	hSpCas9	negative selection	12076839
89467630	89467653	12	-	28162770	MONOMAC1	viability	GGAGAGCTATTTGCATCAGGAGG	POC1B	ENSG00000139323	0.4659281656628756	[83]	[132]	4	hSpCas9	negative selection	12076840
89466813	89466836	12	+	28162770	MONOMAC1	viability	GGGTAGATATCAAGAAGATGTGG	POC1B	ENSG00000139323	-0.6208445559661298	[219]	[163]	-5	hSpCas9	negative selection	12076841
89492056	89492079	12	+	28162770	MONOMAC1	viability	GAAAAGTCTACACTTCGAACTGG	POC1B	ENSG00000139323	0.8029631529404462	[47]	[95]	7	hSpCas9	negative selection	12076842
89471682	89471705	12	+	28162770	MONOMAC1	viability	GAAGCTATGCATGTACCACTAGG	POC1B	ENSG00000139323	0.08215332716528101	[369]	[448]	0	hSpCas9	negative selection	12076843
89497230	89497253	12	+	28162770	OCIAML2	viability	ATGTGGAGAAAACTGCACGCTGG	POC1B	ENSG00000139323	-0.20913758421677292	[38]	[186]	-2	hSpCas9	negative selection	12246200
89466790	89466813	12	-	28162770	OCIAML2	viability	AAGAACACCACATCCCCATGAGG	POC1B	ENSG00000139323	0.4153949825031349	[129]	[960]	4	hSpCas9	negative selection	12246201
89491967	89491990	12	+	28162770	OCIAML2	viability	ACAAGGAATACAGGAAGCGCTGG	POC1B	ENSG00000139323	0.9063396332031632	[35]	[373]	8	hSpCas9	negative selection	12246202
89425327	89425350	12	-	28162770	OCIAML2	viability	GACAAGGGTGAAGAGGCCTGTGG	POC1B	ENSG00000139323	-0.15673904942021694	[35]	[178]	-1	hSpCas9	negative selection	12246203
89470482	89470505	12	-	28162770	OCIAML2	viability	TACAAATCAGTTCACAGCGGTGG	POC1B	ENSG00000139323	0.5266352070366002	[65]	[526]	5	hSpCas9	negative selection	12246204
89470441	89470464	12	+	28162770	OCIAML2	viability	TGAGATAGTTACCCGAAGGATGG	POC1B	ENSG00000139323	0.47690275486370304	[6]	[53]	4	hSpCas9	negative selection	12246205
89467630	89467653	12	-	28162770	OCIAML2	viability	GGAGAGCTATTTGCATCAGGAGG	POC1B	ENSG00000139323	-0.06123888910445929	[15]	[84]	0	hSpCas9	negative selection	12246206
89466813	89466836	12	+	28162770	OCIAML2	viability	GGGTAGATATCAAGAAGATGTGG	POC1B	ENSG00000139323	0.10039348452112107	[51]	[308]	1	hSpCas9	negative selection	12246207
89492056	89492079	12	+	28162770	OCIAML2	viability	GAAAAGTCTACACTTCGAACTGG	POC1B	ENSG00000139323	0.4531345889307534	[16]	[128]	4	hSpCas9	negative selection	12246208
89471682	89471705	12	+	28162770	OCIAML2	viability	GAAGCTATGCATGTACCACTAGG	POC1B	ENSG00000139323	0.7577414485837082	[85]	[805]	7	hSpCas9	negative selection	12246209
89497230	89497253	12	+	28162770	OCIAML3	viability	ATGTGGAGAAAACTGCACGCTGG	POC1B	ENSG00000139323	-0.6060804726247381	[59]	[118]	-4	hSpCas9	negative selection	12415566
89466790	89466813	12	-	28162770	OCIAML3	viability	AAGAACACCACATCCCCATGAGG	POC1B	ENSG00000139323	0.1934477242957362	[218]	[755]	1	hSpCas9	negative selection	12415567
89491967	89491990	12	+	28162770	OCIAML3	viability	ACAAGGAATACAGGAAGCGCTGG	POC1B	ENSG00000139323	0.7945576475934897	[54]	[287]	7	hSpCas9	negative selection	12415568
89425327	89425350	12	-	28162770	OCIAML3	viability	GACAAGGGTGAAGAGGCCTGTGG	POC1B	ENSG00000139323	-0.521251297888849	[57]	[121]	-4	hSpCas9	negative selection	12415569
89470482	89470505	12	-	28162770	OCIAML3	viability	TACAAATCAGTTCACAGCGGTGG	POC1B	ENSG00000139323	0.19186755432298952	[115]	[399]	1	hSpCas9	negative selection	12415570
89470441	89470464	12	+	28162770	OCIAML3	viability	TGAGATAGTTACCCGAAGGATGG	POC1B	ENSG00000139323	-2.371615218987715	[11]	[6]	-9	hSpCas9	negative selection	12415571
89467630	89467653	12	-	28162770	OCIAML3	viability	GGAGAGCTATTTGCATCAGGAGG	POC1B	ENSG00000139323	-0.3309732344903693	[29]	[71]	-3	hSpCas9	negative selection	12415572
89466813	89466836	12	+	28162770	OCIAML3	viability	GGGTAGATATCAAGAAGATGTGG	POC1B	ENSG00000139323	-0.4323692500668116	[96]	[216]	-3	hSpCas9	negative selection	12415573
89492056	89492079	12	+	28162770	OCIAML3	viability	GAAAAGTCTACACTTCGAACTGG	POC1B	ENSG00000139323	0.32882449915337675	[23]	[90]	3	hSpCas9	negative selection	12415574
89471682	89471705	12	+	28162770	OCIAML3	viability	GAAGCTATGCATGTACCACTAGG	POC1B	ENSG00000139323	0.12261750555786732	[149]	[492]	1	hSpCas9	negative selection	12415575