Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:5566
• Symbol:PRKACA
• Description:protein kinase cAMP-activated catalytic subunit alpha

DataSource: http://genomecrispr.dkfz.de/#!/results/PRKACA

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
14106759	14106782	19	-	26472758	Jiyoye	viability	GAAGATCCTCGACAAACAGAAGG	PRKACA	ENSG00000072062	0.10761509964696536	[15]	[12]	0	hSpCas9	negative selection	127293
14097395	14097418	19	+	26472758	Jiyoye	viability	GGCTGGTCTGCGAAGAAGGGCGG	PRKACA	ENSG00000072062	-2.4643098779714463	[160]	[21]	-9	hSpCas9	negative selection	127294
14100865	14100888	19	-	26472758	Jiyoye	viability	GTCATGGAGTACGTGCCCGGCGG	PRKACA	ENSG00000072062	0.8112417629637142	[98]	[130]	5	hSpCas9	negative selection	127295
14100840	14100863	19	-	26472758	Jiyoye	viability	AGATGTTCTCACACCTACGGCGG	PRKACA	ENSG00000072062	0.14203331271008826	[136]	[113]	1	hSpCas9	negative selection	127296
14097406	14097429	19	+	26472758	Jiyoye	viability	GAAGAAGGGCGGGTAGCCAGCGG	PRKACA	ENSG00000072062	-0.22085584110716883	[33]	[21]	-1	hSpCas9	negative selection	127297
14106840	14106863	19	-	26472758	Jiyoye	viability	ACGAATCAAGACCCTCGGCACGG	PRKACA	ENSG00000072062	1.4802388436955969	[76]	[161]	8	hSpCas9	negative selection	127298
14106826	14106849	19	-	26472758	Jiyoye	viability	TCGGCACGGGCTCCTTCGGGCGG	PRKACA	ENSG00000072062	0.4303827726671987	[184]	[187]	3	hSpCas9	negative selection	127299
14102821	14102844	19	+	26472758	Jiyoye	viability	AGGAGAACTCGAGTTTGACGAGG	PRKACA	ENSG00000072062	-0.20580149538487924	[51]	[33]	-1	hSpCas9	negative selection	127300
14097862	14097885	19	+	26472758	Jiyoye	viability	GGGCCGCGTAGAAACGGGCATGG	PRKACA	ENSG00000072062	0.4946382227562127	[31]	[33]	4	hSpCas9	negative selection	127301
14097465	14097488	19	-	26472758	Jiyoye	viability	CCAGGGCTACAACAAGGCCGTGG	PRKACA	ENSG00000072062	-0.21900978194179577	[70]	[45]	-1	hSpCas9	negative selection	127302
14106759	14106782	19	-	26472758	KBM7	viability	GAAGATCCTCGACAAACAGAAGG	PRKACA	ENSG00000072062	-2.1642764142392754	[112,70]	[9,8]	-8	hSpCas9	negative selection	318411
14097395	14097418	19	+	26472758	KBM7	viability	GGCTGGTCTGCGAAGAAGGGCGG	PRKACA	ENSG00000072062	0.18338768087957735	[148,178]	[82,93]	1	hSpCas9	negative selection	318412
14100865	14100888	19	-	26472758	KBM7	viability	GTCATGGAGTACGTGCCCGGCGG	PRKACA	ENSG00000072062	0.986021382851346	[497,329]	[408,352]	9	hSpCas9	negative selection	318413
14100840	14100863	19	-	26472758	KBM7	viability	AGATGTTCTCACACCTACGGCGG	PRKACA	ENSG00000072062	0.2361070283480071	[562,378]	[324,195]	2	hSpCas9	negative selection	318414
14097406	14097429	19	+	26472758	KBM7	viability	GAAGAAGGGCGGGTAGCCAGCGG	PRKACA	ENSG00000072062	0.5892047167996384	[108,43]	[60,43]	6	hSpCas9	negative selection	318415
14106840	14106863	19	-	26472758	KBM7	viability	ACGAATCAAGACCCTCGGCACGG	PRKACA	ENSG00000072062	1.0431735151996935	[799,451]	[794,410]	9	hSpCas9	negative selection	318416
14106826	14106849	19	-	26472758	KBM7	viability	TCGGCACGGGCTCCTTCGGGCGG	PRKACA	ENSG00000072062	0.5531956238414466	[660,574]	[445,406]	6	hSpCas9	negative selection	318417
14102821	14102844	19	+	26472758	KBM7	viability	AGGAGAACTCGAGTTTGACGAGG	PRKACA	ENSG00000072062	0.7195894676378208	[174,189]	[140,143]	7	hSpCas9	negative selection	318418
14097862	14097885	19	+	26472758	KBM7	viability	GGGCCGCGTAGAAACGGGCATGG	PRKACA	ENSG00000072062	0.0813090222323245	[218,291]	[80,172]	0	hSpCas9	negative selection	318419
14097465	14097488	19	-	26472758	KBM7	viability	CCAGGGCTACAACAAGGCCGTGG	PRKACA	ENSG00000072062	-0.6192233850034838	[210,85]	[48,38]	-5	hSpCas9	negative selection	318420
14106759	14106782	19	-	26472758	Raji	viability	GAAGATCCTCGACAAACAGAAGG	PRKACA	ENSG00000072062	1.153187224986724	[30]	[15]	8	hSpCas9	negative selection	509529
14097395	14097418	19	+	26472758	Raji	viability	GGCTGGTCTGCGAAGAAGGGCGG	PRKACA	ENSG00000072062	-0.6340834510275475	[106]	[15]	-5	hSpCas9	negative selection	509530
14100865	14100888	19	-	26472758	Raji	viability	GTCATGGAGTACGTGCCCGGCGG	PRKACA	ENSG00000072062	-0.5334322000810741	[236]	[37]	-4	hSpCas9	negative selection	509531
14100840	14100863	19	-	26472758	Raji	viability	AGATGTTCTCACACCTACGGCGG	PRKACA	ENSG00000072062	0.18830353075716685	[207]	[54]	1	hSpCas9	negative selection	509532
14097406	14097429	19	+	26472758	Raji	viability	GAAGAAGGGCGGGTAGCCAGCGG	PRKACA	ENSG00000072062	-1.8622428155828823	[46]	[2]	-8	hSpCas9	negative selection	509533
14106840	14106863	19	-	26472758	Raji	viability	ACGAATCAAGACCCTCGGCACGG	PRKACA	ENSG00000072062	0.7474875902872167	[307]	[119]	7	hSpCas9	negative selection	509534
14106826	14106849	19	-	26472758	Raji	viability	TCGGCACGGGCTCCTTCGGGCGG	PRKACA	ENSG00000072062	-0.7216664577833237	[468]	[65]	-5	hSpCas9	negative selection	509535
14102821	14102844	19	+	26472758	Raji	viability	AGGAGAACTCGAGTTTGACGAGG	PRKACA	ENSG00000072062	-0.14415523162236488	[99]	[20]	-1	hSpCas9	negative selection	509536
14097862	14097885	19	+	26472758	Raji	viability	GGGCCGCGTAGAAACGGGCATGG	PRKACA	ENSG00000072062	-1.0218994815713671	[139]	[15]	-6	hSpCas9	negative selection	509537
14097465	14097488	19	-	26472758	Raji	viability	CCAGGGCTACAACAAGGCCGTGG	PRKACA	ENSG00000072062	0.14055039930879876	[128]	[32]	1	hSpCas9	negative selection	509538
14106759	14106782	19	-	26472758	K562	viability	GAAGATCCTCGACAAACAGAAGG	PRKACA	ENSG00000072062	-1.3405437730547094	[77]	[25]	-6	hSpCas9	negative selection	700647
14097395	14097418	19	+	26472758	K562	viability	GGCTGGTCTGCGAAGAAGGGCGG	PRKACA	ENSG00000072062	-2.374491104978047	[128]	[20]	-8	hSpCas9	negative selection	700648
14100865	14100888	19	-	26472758	K562	viability	GTCATGGAGTACGTGCCCGGCGG	PRKACA	ENSG00000072062	0.9041300956577448	[256]	[405]	7	hSpCas9	negative selection	700649
14100840	14100863	19	-	26472758	K562	viability	AGATGTTCTCACACCTACGGCGG	PRKACA	ENSG00000072062	-1.1051657101237808	[394]	[154]	-6	hSpCas9	negative selection	700650
14097406	14097429	19	+	26472758	K562	viability	GAAGAAGGGCGGGTAGCCAGCGG	PRKACA	ENSG00000072062	-2.646352202578795	[88]	[11]	-8	hSpCas9	negative selection	700651
14106840	14106863	19	-	26472758	K562	viability	ACGAATCAAGACCCTCGGCACGG	PRKACA	ENSG00000072062	-0.2599945789430898	[565]	[398]	-2	hSpCas9	negative selection	700652
14106826	14106849	19	-	26472758	K562	viability	TCGGCACGGGCTCCTTCGGGCGG	PRKACA	ENSG00000072062	0.8879222808546872	[490]	[766]	7	hSpCas9	negative selection	700653
14102821	14102844	19	+	26472758	K562	viability	AGGAGAACTCGAGTTTGACGAGG	PRKACA	ENSG00000072062	0.10294630171356633	[181]	[164]	0	hSpCas9	negative selection	700654
14097862	14097885	19	+	26472758	K562	viability	GGGCCGCGTAGAAACGGGCATGG	PRKACA	ENSG00000072062	-0.9542250908973919	[240]	[104]	-5	hSpCas9	negative selection	700655
14097465	14097488	19	-	26472758	K562	viability	CCAGGGCTACAACAAGGCCGTGG	PRKACA	ENSG00000072062	0.40839446277757285	[107]	[120]	3	hSpCas9	negative selection	700656
14097396	14097419	19	+	26627737	DLD1	viability	GCTGGTCTGCGAAGAAGGGCGGG	PRKACA	ENSG00000072062	-0.48777791440216367	[192]	[110,18,3]	-5	hSpCas9	negative selection	802880
14097862	14097885	19	+	26627737	DLD1	viability	GGGCCGCGTAGAAACGGGCATGG	PRKACA	ENSG00000072062	-1.254892607737268	[276]	[26,55,27]	-8	hSpCas9	negative selection	802881
14100840	14100863	19	-	26627737	DLD1	viability	AGATGTTCTCACACCTACGGCGG	PRKACA	ENSG00000072062	0.29635612492404345	[496]	[202,155,208]	3	hSpCas9	negative selection	802882
14106840	14106863	19	-	26627737	DLD1	viability	ACGAATCAAGACCCTCGGCACGG	PRKACA	ENSG00000072062	0.8437443306950978	[606]	[133,566,331]	7	hSpCas9	negative selection	802883
14107334	14107357	19	+	26627737	DLD1	viability	CCCGGCAGCCTTACCTGAGCGGG	PRKACA	ENSG00000072062	-0.028979653432225083	[1179]	[242,391,438]	0	hSpCas9	negative selection	802884
14117519	14117542	19	-	26627737	DLD1	viability	AACGCCGCCGCCGCCAAGAAGGG	PRKACA	ENSG00000072062	0.1896626285778622	[317]	[86,138,114]	2	hSpCas9	negative selection	802886
14097396	14097419	19	+	26627737	GBM cells	viability after 5 days	GCTGGTCTGCGAAGAAGGGCGGG	PRKACA	ENSG00000072062	0.9630442123054008	[10]	[16,5]	9	hSpCas9	negative selection	885195
14097862	14097885	19	+	26627737	GBM cells	viability after 5 days	GGGCCGCGTAGAAACGGGCATGG	PRKACA	ENSG00000072062	0.2208419697730477	[71]	[44,44]	3	hSpCas9	negative selection	885196
14100840	14100863	19	-	26627737	GBM cells	viability after 5 days	AGATGTTCTCACACCTACGGCGG	PRKACA	ENSG00000072062	-0.41059496074760893	[346]	[117,161]	-6	hSpCas9	negative selection	885197
14106840	14106863	19	-	26627737	GBM cells	viability after 5 days	ACGAATCAAGACCCTCGGCACGG	PRKACA	ENSG00000072062	0.04085251349115748	[560]	[316,301]	0	hSpCas9	negative selection	885198
14107334	14107357	19	+	26627737	GBM cells	viability after 5 days	CCCGGCAGCCTTACCTGAGCGGG	PRKACA	ENSG00000072062	-0.2687301853053883	[473]	[198,222]	-4	hSpCas9	negative selection	885199
14117519	14117542	19	-	26627737	GBM cells	viability after 5 days	AACGCCGCCGCCGCCAAGAAGGG	PRKACA	ENSG00000072062	0.04169843830135689	[470]	[282,236]	0	hSpCas9	negative selection	885201
14097396	14097419	19	+	26627737	GBM cells	viability after 13 days	GCTGGTCTGCGAAGAAGGGCGGG	PRKACA	ENSG00000072062	0.8129669301346989	[10]	[15,5]	8	hSpCas9	negative selection	967510
14097862	14097885	19	+	26627737	GBM cells	viability after 13 days	GGGCCGCGTAGAAACGGGCATGG	PRKACA	ENSG00000072062	0.24882531664878393	[71]	[57,36]	3	hSpCas9	negative selection	967511
14100840	14100863	19	-	26627737	GBM cells	viability after 13 days	AGATGTTCTCACACCTACGGCGG	PRKACA	ENSG00000072062	-0.40313669729170165	[346]	[132,149]	-5	hSpCas9	negative selection	967512
14106840	14106863	19	-	26627737	GBM cells	viability after 13 days	ACGAATCAAGACCCTCGGCACGG	PRKACA	ENSG00000072062	-0.47666312507665143	[560]	[258,185]	-5	hSpCas9	negative selection	967513
14107334	14107357	19	+	26627737	GBM cells	viability after 13 days	CCCGGCAGCCTTACCTGAGCGGG	PRKACA	ENSG00000072062	-0.2932030666498463	[473]	[178,234]	-4	hSpCas9	negative selection	967514
14117519	14117542	19	-	26627737	GBM cells	viability after 13 days	AACGCCGCCGCCGCCAAGAAGGG	PRKACA	ENSG00000072062	0.24779293396327184	[470]	[362,254]	3	hSpCas9	negative selection	967516
14097396	14097419	19	+	26627737	GBM cells	viability after 21 days	GCTGGTCTGCGAAGAAGGGCGGG	PRKACA	ENSG00000072062	0.79158594220748	[10]	[13,6]	7	hSpCas9	negative selection	1049825
14097862	14097885	19	+	26627737	GBM cells	viability after 21 days	GGGCCGCGTAGAAACGGGCATGG	PRKACA	ENSG00000072062	-0.9709731634151817	[71]	[20,18]	-7	hSpCas9	negative selection	1049826
14100840	14100863	19	-	26627737	GBM cells	viability after 21 days	AGATGTTCTCACACCTACGGCGG	PRKACA	ENSG00000072062	-0.44458492613305417	[346]	[137,138]	-4	hSpCas9	negative selection	1049827
14106840	14106863	19	-	26627737	GBM cells	viability after 21 days	ACGAATCAAGACCCTCGGCACGG	PRKACA	ENSG00000072062	-0.5033562554469181	[560]	[202,225]	-4	hSpCas9	negative selection	1049828
14107334	14107357	19	+	26627737	GBM cells	viability after 21 days	CCCGGCAGCCTTACCTGAGCGGG	PRKACA	ENSG00000072062	-0.1984382212507212	[473]	[237,211]	-2	hSpCas9	negative selection	1049829
14117519	14117542	19	-	26627737	GBM cells	viability after 21 days	AACGCCGCCGCCGCCAAGAAGGG	PRKACA	ENSG00000072062	0.4322637245004104	[470]	[373,318]	4	hSpCas9	negative selection	1049831
14097396	14097419	19	+	26627737	RPE1	viability after 9 days	GCTGGTCTGCGAAGAAGGGCGGG	PRKACA	ENSG00000072062	-0.8237778698255822	[284]	[35,68]	-5	hSpCas9	negative selection	1132140
14097862	14097885	19	+	26627737	RPE1	viability after 9 days	GGGCCGCGTAGAAACGGGCATGG	PRKACA	ENSG00000072062	1.149677135025739	[208]	[135,156]	7	hSpCas9	negative selection	1132141
14100840	14100863	19	-	26627737	RPE1	viability after 9 days	AGATGTTCTCACACCTACGGCGG	PRKACA	ENSG00000072062	-1.0629299499390978	[1267]	[134,260]	-6	hSpCas9	negative selection	1132142
14106840	14106863	19	-	26627737	RPE1	viability after 9 days	ACGAATCAAGACCCTCGGCACGG	PRKACA	ENSG00000072062	-0.1310115023384666	[1675]	[524,419]	-1	hSpCas9	negative selection	1132143
14107334	14107357	19	+	26627737	RPE1	viability after 9 days	CCCGGCAGCCTTACCTGAGCGGG	PRKACA	ENSG00000072062	-0.2914032393295356	[1998]	[475,556]	-2	hSpCas9	negative selection	1132144
14117519	14117542	19	-	26627737	RPE1	viability after 9 days	AACGCCGCCGCCGCCAAGAAGGG	PRKACA	ENSG00000072062	0.19002369129381813	[1018]	[328,408]	1	hSpCas9	negative selection	1132146
14097396	14097419	19	+	26627737	RPE1	viability after 12 days	GCTGGTCTGCGAAGAAGGGCGGG	PRKACA	ENSG00000072062	-0.6132026547227591	[284]	[68,29]	-4	hSpCas9	negative selection	1214455
14097862	14097885	19	+	26627737	RPE1	viability after 12 days	GGGCCGCGTAGAAACGGGCATGG	PRKACA	ENSG00000072062	1.8416484564784972	[208]	[192,209]	8	hSpCas9	negative selection	1214456
14100840	14100863	19	-	26627737	RPE1	viability after 12 days	AGATGTTCTCACACCTACGGCGG	PRKACA	ENSG00000072062	-0.6342443868801707	[1267]	[218,219]	-4	hSpCas9	negative selection	1214457
14106840	14106863	19	-	26627737	RPE1	viability after 12 days	ACGAATCAAGACCCTCGGCACGG	PRKACA	ENSG00000072062	-0.47166797526597015	[1675]	[348,298]	-3	hSpCas9	negative selection	1214458
14107334	14107357	19	+	26627737	RPE1	viability after 12 days	CCCGGCAGCCTTACCTGAGCGGG	PRKACA	ENSG00000072062	-0.17820936164635937	[1998]	[360,594]	-1	hSpCas9	negative selection	1214459
14117519	14117542	19	-	26627737	RPE1	viability after 12 days	AACGCCGCCGCCGCCAAGAAGGG	PRKACA	ENSG00000072062	0.34730056406993204	[1018]	[391,301]	2	hSpCas9	negative selection	1214461
14097396	14097419	19	+	26627737	RPE1	viability after 15 days	GCTGGTCTGCGAAGAAGGGCGGG	PRKACA	ENSG00000072062	-0.5928840205240993	[284]	[27,77]	-4	hSpCas9	negative selection	1296770
14097862	14097885	19	+	26627737	RPE1	viability after 15 days	GGGCCGCGTAGAAACGGGCATGG	PRKACA	ENSG00000072062	2.1660108558055087	[208]	[246,282]	9	hSpCas9	negative selection	1296771
14100840	14100863	19	-	26627737	RPE1	viability after 15 days	AGATGTTCTCACACCTACGGCGG	PRKACA	ENSG00000072062	-0.8506217685541598	[1267]	[203,193]	-5	hSpCas9	negative selection	1296772
14106840	14106863	19	-	26627737	RPE1	viability after 15 days	ACGAATCAAGACCCTCGGCACGG	PRKACA	ENSG00000072062	0.4178289215114035	[1675]	[837,435]	2	hSpCas9	negative selection	1296773
14107334	14107357	19	+	26627737	RPE1	viability after 15 days	CCCGGCAGCCTTACCTGAGCGGG	PRKACA	ENSG00000072062	-0.8532428960527633	[1998]	[452,177]	-5	hSpCas9	negative selection	1296774
14117519	14117542	19	-	26627737	RPE1	viability after 15 days	AACGCCGCCGCCGCCAAGAAGGG	PRKACA	ENSG00000072062	0.22581237004132326	[1018]	[359,314]	1	hSpCas9	negative selection	1296776
14097396	14097419	19	+	26627737	RPE1	viability after 18 days	GCTGGTCTGCGAAGAAGGGCGGG	PRKACA	ENSG00000072062	-0.3096307740700277	[284]	[19,106]	-2	hSpCas9	negative selection	1379085
14097862	14097885	19	+	26627737	RPE1	viability after 18 days	GGGCCGCGTAGAAACGGGCATGG	PRKACA	ENSG00000072062	3.131063853478643	[208]	[293,707]	9	hSpCas9	negative selection	1379086
14100840	14100863	19	-	26627737	RPE1	viability after 18 days	AGATGTTCTCACACCTACGGCGG	PRKACA	ENSG00000072062	-1.455404851676382	[1267]	[132,115]	-7	hSpCas9	negative selection	1379087
14106840	14106863	19	-	26627737	RPE1	viability after 18 days	ACGAATCAAGACCCTCGGCACGG	PRKACA	ENSG00000072062	0.4969494503908365	[1675]	[646,628]	3	hSpCas9	negative selection	1379088
14107334	14107357	19	+	26627737	RPE1	viability after 18 days	CCCGGCAGCCTTACCTGAGCGGG	PRKACA	ENSG00000072062	-0.15753461774983113	[1998]	[502,462]	-1	hSpCas9	negative selection	1379089
14117519	14117542	19	-	26627737	RPE1	viability after 18 days	AACGCCGCCGCCGCCAAGAAGGG	PRKACA	ENSG00000072062	0.6301388857390642	[1018]	[428,421]	4	hSpCas9	negative selection	1379091
14097396	14097419	19	+	26627737	HeLa	viability after 8 days	GCTGGTCTGCGAAGAAGGGCGGG	PRKACA	ENSG00000072062	-0.12339433658891052	[186]	[13,199,1]	-1	hSpCas9	negative selection	1461400
14097862	14097885	19	+	26627737	HeLa	viability after 8 days	GGGCCGCGTAGAAACGGGCATGG	PRKACA	ENSG00000072062	-0.14156674891962484	[218]	[127,63,76]	-1	hSpCas9	negative selection	1461401
14100840	14100863	19	-	26627737	HeLa	viability after 8 days	AGATGTTCTCACACCTACGGCGG	PRKACA	ENSG00000072062	-0.4705931800445296	[350]	[32,204,77]	-4	hSpCas9	negative selection	1461402
14106840	14106863	19	-	26627737	HeLa	viability after 8 days	ACGAATCAAGACCCTCGGCACGG	PRKACA	ENSG00000072062	-0.5326722920174941	[840]	[319,101,344]	-5	hSpCas9	negative selection	1461403
14107334	14107357	19	+	26627737	HeLa	viability after 8 days	CCCGGCAGCCTTACCTGAGCGGG	PRKACA	ENSG00000072062	-0.5973440374101746	[1325]	[709,162,345]	-5	hSpCas9	negative selection	1461404
14117519	14117542	19	-	26627737	HeLa	viability after 8 days	AACGCCGCCGCCGCCAAGAAGGG	PRKACA	ENSG00000072062	0.4122591926495123	[490]	[210,358,267]	4	hSpCas9	negative selection	1461406
14097396	14097419	19	+	26627737	HeLa	viability after 12 days	GCTGGTCTGCGAAGAAGGGCGGG	PRKACA	ENSG00000072062	-0.9934935293154652	[186]	[43,34,37]	-7	hSpCas9	negative selection	1543715
14097862	14097885	19	+	26627737	HeLa	viability after 12 days	GGGCCGCGTAGAAACGGGCATGG	PRKACA	ENSG00000072062	0.5839261712066923	[218]	[191,65,157]	5	hSpCas9	negative selection	1543716
14100840	14100863	19	-	26627737	HeLa	viability after 12 days	AGATGTTCTCACACCTACGGCGG	PRKACA	ENSG00000072062	-0.45613241241137553	[350]	[49,82,184]	-4	hSpCas9	negative selection	1543717
14106840	14106863	19	-	26627737	HeLa	viability after 12 days	ACGAATCAAGACCCTCGGCACGG	PRKACA	ENSG00000072062	-0.3062100953780664	[840]	[405,232,212]	-3	hSpCas9	negative selection	1543718
14107334	14107357	19	+	26627737	HeLa	viability after 12 days	CCCGGCAGCCTTACCTGAGCGGG	PRKACA	ENSG00000072062	-0.8435205077824798	[1325]	[340,259,320]	-6	hSpCas9	negative selection	1543719
14117519	14117542	19	-	26627737	HeLa	viability after 12 days	AACGCCGCCGCCGCCAAGAAGGG	PRKACA	ENSG00000072062	0.21132286173478187	[490]	[254,275,169]	2	hSpCas9	negative selection	1543721
14097396	14097419	19	+	26627737	HeLa	viability after 15 days	GCTGGTCTGCGAAGAAGGGCGGG	PRKACA	ENSG00000072062	0.3362123114313723	[186]	[72,126,87]	3	hSpCas9	negative selection	1626030
14097862	14097885	19	+	26627737	HeLa	viability after 15 days	GGGCCGCGTAGAAACGGGCATGG	PRKACA	ENSG00000072062	0.4015713567287026	[218]	[45,144,166]	3	hSpCas9	negative selection	1626031
14100840	14100863	19	-	26627737	HeLa	viability after 15 days	AGATGTTCTCACACCTACGGCGG	PRKACA	ENSG00000072062	-0.8524218410583433	[350]	[31,78,130]	-6	hSpCas9	negative selection	1626032
14106840	14106863	19	-	26627737	HeLa	viability after 15 days	ACGAATCAAGACCCTCGGCACGG	PRKACA	ENSG00000072062	-0.22663399743495694	[840]	[40,221,644]	-2	hSpCas9	negative selection	1626033
14107334	14107357	19	+	26627737	HeLa	viability after 15 days	CCCGGCAGCCTTACCTGAGCGGG	PRKACA	ENSG00000072062	-1.0715713716448851	[1325]	[350,104,317]	-7	hSpCas9	negative selection	1626034
14117519	14117542	19	-	26627737	HeLa	viability after 15 days	AACGCCGCCGCCGCCAAGAAGGG	PRKACA	ENSG00000072062	0.49514851666354653	[490]	[455,152,229]	4	hSpCas9	negative selection	1626036
14097396	14097419	19	+	26627737	HeLa	viability after 18 days	GCTGGTCTGCGAAGAAGGGCGGG	PRKACA	ENSG00000072062	0.2946558949002489	[186]	[42,105,87]	2	hSpCas9	negative selection	1708345
14097862	14097885	19	+	26627737	HeLa	viability after 18 days	GGGCCGCGTAGAAACGGGCATGG	PRKACA	ENSG00000072062	0.4096384295404424	[218]	[28,123,166]	3	hSpCas9	negative selection	1708346
14100840	14100863	19	-	26627737	HeLa	viability after 18 days	AGATGTTCTCACACCTACGGCGG	PRKACA	ENSG00000072062	-0.8027022979524929	[350]	[23,68,130]	-6	hSpCas9	negative selection	1708347
14106840	14106863	19	-	26627737	HeLa	viability after 18 days	ACGAATCAAGACCCTCGGCACGG	PRKACA	ENSG00000072062	-0.2209848679479638	[840]	[27,185,644]	-2	hSpCas9	negative selection	1708348
14107334	14107357	19	+	26627737	HeLa	viability after 18 days	CCCGGCAGCCTTACCTGAGCGGG	PRKACA	ENSG00000072062	-1.0522494584677764	[1325]	[242,85,317]	-7	hSpCas9	negative selection	1708349
14117519	14117542	19	-	26627737	HeLa	viability after 18 days	AACGCCGCCGCCGCCAAGAAGGG	PRKACA	ENSG00000072062	0.4932739385301499	[490]	[308,121,229]	4	hSpCas9	negative selection	1708351
14097396	14097419	19	+	26627737	HCT116	viability after 6 days	GCTGGTCTGCGAAGAAGGGCGGG	PRKACA	ENSG00000072062	-0.07470425796101643	[472]	[29,92]	0	hSpCas9	negative selection	1790660
14097862	14097885	19	+	26627737	HCT116	viability after 6 days	GGGCCGCGTAGAAACGGGCATGG	PRKACA	ENSG00000072062	1.5908999004807391	[154]	[55,82]	7	hSpCas9	negative selection	1790661
14100840	14100863	19	-	26627737	HCT116	viability after 6 days	AGATGTTCTCACACCTACGGCGG	PRKACA	ENSG00000072062	-1.2828108953229107	[642]	[105,5]	-6	hSpCas9	negative selection	1790662
14106840	14106863	19	-	26627737	HCT116	viability after 6 days	ACGAATCAAGACCCTCGGCACGG	PRKACA	ENSG00000072062	1.0197350734573207	[1296]	[881,154]	5	hSpCas9	negative selection	1790663
14107334	14107357	19	+	26627737	HCT116	viability after 6 days	CCCGGCAGCCTTACCTGAGCGGG	PRKACA	ENSG00000072062	0.9641963394919337	[1109]	[333,343]	5	hSpCas9	negative selection	1790664
14117519	14117542	19	-	26627737	HCT116	viability after 6 days	AACGCCGCCGCCGCCAAGAAGGG	PRKACA	ENSG00000072062	-0.1685133607829938	[787]	[242,36]	-1	hSpCas9	negative selection	1790666
14097396	14097419	19	+	26627737	HCT116	viability after 8 days	GCTGGTCTGCGAAGAAGGGCGGG	PRKACA	ENSG00000072062	-1.0683442807708792	[166]	[58,35,36]	-8	hSpCas9	negative selection	1872975
14097862	14097885	19	+	26627737	HCT116	viability after 8 days	GGGCCGCGTAGAAACGGGCATGG	PRKACA	ENSG00000072062	-0.1661639185626056	[168]	[52,75,118]	-2	hSpCas9	negative selection	1872976
14100840	14100863	19	-	26627737	HCT116	viability after 8 days	AGATGTTCTCACACCTACGGCGG	PRKACA	ENSG00000072062	-0.5861576104198086	[456]	[181,196,124]	-6	hSpCas9	negative selection	1872977
14106840	14106863	19	-	26627737	HCT116	viability after 8 days	ACGAATCAAGACCCTCGGCACGG	PRKACA	ENSG00000072062	-0.18808061223809913	[639]	[282,402,242]	-2	hSpCas9	negative selection	1872978
14107334	14107357	19	+	26627737	HCT116	viability after 8 days	CCCGGCAGCCTTACCTGAGCGGG	PRKACA	ENSG00000072062	-0.1331959305221746	[818]	[439,384,409]	-1	hSpCas9	negative selection	1872979
14117519	14117542	19	-	26627737	HCT116	viability after 8 days	AACGCCGCCGCCGCCAAGAAGGG	PRKACA	ENSG00000072062	0.7844199604681137	[260]	[206,253,280]	7	hSpCas9	negative selection	1872981
14097396	14097419	19	+	26627737	HCT116	viability after 9 days	GCTGGTCTGCGAAGAAGGGCGGG	PRKACA	ENSG00000072062	-1.2176587267382089	[472]	[79,33]	-7	hSpCas9	negative selection	1955290
14097862	14097885	19	+	26627737	HCT116	viability after 9 days	GGGCCGCGTAGAAACGGGCATGG	PRKACA	ENSG00000072062	1.0480094672055835	[154]	[184,6]	7	hSpCas9	negative selection	1955291
14100840	14100863	19	-	26627737	HCT116	viability after 9 days	AGATGTTCTCACACCTACGGCGG	PRKACA	ENSG00000072062	-4.335457932962743	[642]	[17,0]	-9	hSpCas9	negative selection	1955292
14106840	14106863	19	-	26627737	HCT116	viability after 9 days	ACGAATCAAGACCCTCGGCACGG	PRKACA	ENSG00000072062	-0.4131553051082806	[1296]	[368,173]	-3	hSpCas9	negative selection	1955293
14107334	14107357	19	+	26627737	HCT116	viability after 9 days	CCCGGCAGCCTTACCTGAGCGGG	PRKACA	ENSG00000072062	0.646150574192357	[1109]	[450,473]	5	hSpCas9	negative selection	1955294
14117519	14117542	19	-	26627737	HCT116	viability after 9 days	AACGCCGCCGCCGCCAAGAAGGG	PRKACA	ENSG00000072062	-0.0005901087590018395	[787]	[211,208]	0	hSpCas9	negative selection	1955296
14097396	14097419	19	+	26627737	HCT116	viability after 12 days	GCTGGTCTGCGAAGAAGGGCGGG	PRKACA	ENSG00000072062	-0.5320553626782978	[166]	[81,51,45]	-5	hSpCas9	negative selection	2037605
14097862	14097885	19	+	26627737	HCT116	viability after 12 days	GGGCCGCGTAGAAACGGGCATGG	PRKACA	ENSG00000072062	0.275727026897416	[168]	[90,65,165]	3	hSpCas9	negative selection	2037606
14100840	14100863	19	-	26627737	HCT116	viability after 12 days	AGATGTTCTCACACCTACGGCGG	PRKACA	ENSG00000072062	-0.7834603429020857	[456]	[125,189,104]	-7	hSpCas9	negative selection	2037607
14106840	14106863	19	-	26627737	HCT116	viability after 12 days	ACGAATCAAGACCCTCGGCACGG	PRKACA	ENSG00000072062	0.12072312149636244	[639]	[303,468,331]	1	hSpCas9	negative selection	2037608
14107334	14107357	19	+	26627737	HCT116	viability after 12 days	CCCGGCAGCCTTACCTGAGCGGG	PRKACA	ENSG00000072062	0.0265238762401947	[818]	[397,490,430]	0	hSpCas9	negative selection	2037609
14117519	14117542	19	-	26627737	HCT116	viability after 12 days	AACGCCGCCGCCGCCAAGAAGGG	PRKACA	ENSG00000072062	0.58129753962732	[260]	[131,324,167]	5	hSpCas9	negative selection	2037611
14097396	14097419	19	+	26627737	HCT116	viability after 15 days	GCTGGTCTGCGAAGAAGGGCGGG	PRKACA	ENSG00000072062	-1.0088698906454137	[166]	[63,35,44]	-7	hSpCas9	negative selection	2119920
14097862	14097885	19	+	26627737	HCT116	viability after 15 days	GGGCCGCGTAGAAACGGGCATGG	PRKACA	ENSG00000072062	0.10360937485609167	[168]	[100,69,140]	1	hSpCas9	negative selection	2119921
14100840	14100863	19	-	26627737	HCT116	viability after 15 days	AGATGTTCTCACACCTACGGCGG	PRKACA	ENSG00000072062	-0.8228387985885043	[456]	[202,119,128]	-7	hSpCas9	negative selection	2119922
14106840	14106863	19	-	26627737	HCT116	viability after 15 days	ACGAATCAAGACCCTCGGCACGG	PRKACA	ENSG00000072062	0.13164596078806645	[639]	[575,325,327]	1	hSpCas9	negative selection	2119923
14107334	14107357	19	+	26627737	HCT116	viability after 15 days	CCCGGCAGCCTTACCTGAGCGGG	PRKACA	ENSG00000072062	-0.16141600270497047	[818]	[403,379,474]	-2	hSpCas9	negative selection	2119924
14117519	14117542	19	-	26627737	HCT116	viability after 15 days	AACGCCGCCGCCGCCAAGAAGGG	PRKACA	ENSG00000072062	1.2554137023930696	[260]	[394,320,361]	8	hSpCas9	negative selection	2119926
14097396	14097419	19	+	26627737	HCT116	viability after 18 days	GCTGGTCTGCGAAGAAGGGCGGG	PRKACA	ENSG00000072062	-0.6541700588078387	[166]	[14,73,63]	-5	hSpCas9	negative selection	2202235
14097862	14097885	19	+	26627737	HCT116	viability after 18 days	GGGCCGCGTAGAAACGGGCATGG	PRKACA	ENSG00000072062	-1.1202135135690114	[168]	[50,29,31]	-7	hSpCas9	negative selection	2202236
14100840	14100863	19	-	26627737	HCT116	viability after 18 days	AGATGTTCTCACACCTACGGCGG	PRKACA	ENSG00000072062	-1.395099704994484	[456]	[69,106,72]	-8	hSpCas9	negative selection	2202237
14106840	14106863	19	-	26627737	HCT116	viability after 18 days	ACGAATCAAGACCCTCGGCACGG	PRKACA	ENSG00000072062	0.38279853390825	[639]	[510,395,298]	3	hSpCas9	negative selection	2202238
14107334	14107357	19	+	26627737	HCT116	viability after 18 days	CCCGGCAGCCTTACCTGAGCGGG	PRKACA	ENSG00000072062	-0.090949627022614	[818]	[288,330,503]	-1	hSpCas9	negative selection	2202239
14117519	14117542	19	-	26627737	HCT116	viability after 18 days	AACGCCGCCGCCGCCAAGAAGGG	PRKACA	ENSG00000072062	0.596594223482586	[260]	[227,238,97]	5	hSpCas9	negative selection	2202241
14106778	14106801	19	+	24336569	HL60	viability	CTTCATGGCATAGTGGTTCCCGG	PRKACA	ENSG00000072062	-0.16694490346639723	[590]	[1113]	-1	hSpCas9	negative selection	2286322
14106796	14106819	19	-	24336569	HL60	viability	TGGTGAAACACAAGGAGACCGGG	PRKACA	ENSG00000072062	1.240463994258466	[243]	[1219]	8	hSpCas9	negative selection	2286323
14106804	14106827	19	-	24336569	HL60	viability	GGTGATGCTGGTGAAACACAAGG	PRKACA	ENSG00000072062	0.7605718958960139	[1279]	[4588]	6	hSpCas9	negative selection	2286324
14106825	14106848	19	-	24336569	HL60	viability	CGGCACGGGCTCCTTCGGGCGGG	PRKACA	ENSG00000072062	0.10296047050853119	[659]	[1499]	1	hSpCas9	negative selection	2286325
14106830	14106853	19	-	24336569	HL60	viability	ACCCTCGGCACGGGCTCCTTCGG	PRKACA	ENSG00000072062	1.4155507008165569	[92]	[524]	8	hSpCas9	negative selection	2286326
14106839	14106862	19	-	24336569	HL60	viability	CGAATCAAGACCCTCGGCACGGG	PRKACA	ENSG00000072062	0.5153529864380386	[605]	[1832]	4	hSpCas9	negative selection	2286327
14106845	14106868	19	-	24336569	HL60	viability	TTTGAACGAATCAAGACCCTCGG	PRKACA	ENSG00000072062	0.5390203129307978	[574]	[1767]	5	hSpCas9	negative selection	2286328
14106858	14106881	19	+	24336569	HL60	viability	TTCGTTCAAACTGATCCAAGTGG	PRKACA	ENSG00000072062	-0.1107317397740667	[970]	[1902]	-1	hSpCas9	negative selection	2286329
14106873	14106896	19	-	24336569	HL60	viability	CCCACAGAACACAGCCCACTTGG	PRKACA	ENSG00000072062	1.8254264949796224	[397]	[2984]	9	hSpCas9	negative selection	2286330
14107333	14107356	19	+	24336569	HL60	viability	ACCCGGCAGCCTTACCTGAGCGG	PRKACA	ENSG00000072062	0.5670364326975939	[458]	[1438]	5	hSpCas9	negative selection	2286331
14106778	14106801	19	+	24336569	KBM7	viability	CTTCATGGCATAGTGGTTCCCGG	PRKACA	ENSG00000072062	0.11209238487453488	[632]	[1865]	1	hSpCas9	negative selection	2353499
14106796	14106819	19	-	24336569	KBM7	viability	TGGTGAAACACAAGGAGACCGGG	PRKACA	ENSG00000072062	0.5052139000176774	[364]	[1412]	4	hSpCas9	negative selection	2353500
14106804	14106827	19	-	24336569	KBM7	viability	GGTGATGCTGGTGAAACACAAGG	PRKACA	ENSG00000072062	0.4774023579270985	[1193]	[4533]	4	hSpCas9	negative selection	2353501
14106825	14106848	19	-	24336569	KBM7	viability	CGGCACGGGCTCCTTCGGGCGGG	PRKACA	ENSG00000072062	0.020505733847842322	[543]	[1504]	0	hSpCas9	negative selection	2353502
14106830	14106853	19	-	24336569	KBM7	viability	ACCCTCGGCACGGGCTCCTTCGG	PRKACA	ENSG00000072062	0.3556752157632531	[301]	[1053]	3	hSpCas9	negative selection	2353503
14106839	14106862	19	-	24336569	KBM7	viability	CGAATCAAGACCCTCGGCACGGG	PRKACA	ENSG00000072062	0.8044569657427826	[405]	[1933]	7	hSpCas9	negative selection	2353504
14106845	14106868	19	-	24336569	KBM7	viability	TTTGAACGAATCAAGACCCTCGG	PRKACA	ENSG00000072062	0.4241188376036284	[378]	[1386]	4	hSpCas9	negative selection	2353505
14106858	14106881	19	+	24336569	KBM7	viability	TTCGTTCAAACTGATCCAAGTGG	PRKACA	ENSG00000072062	-0.11669332512996716	[577]	[1453]	-1	hSpCas9	negative selection	2353506
14106873	14106896	19	-	24336569	KBM7	viability	CCCACAGAACACAGCCCACTTGG	PRKACA	ENSG00000072062	0.714755261033064	[486]	[2179]	6	hSpCas9	negative selection	2353507
14107333	14107356	19	+	24336569	KBM7	viability	ACCCGGCAGCCTTACCTGAGCGG	PRKACA	ENSG00000072062	0.7632049809667809	[204]	[948]	6	hSpCas9	negative selection	2353508
14117869	14117892	19	+	25494202	A375	resistance to PLX-4720 (puromycin)	CAGCCTCGGGACACGCACCGCGG	PRKACA	ENSG00000072062	-0.2385224005244435	[24,13]	[3,1]	-1	dCas9-VP64	positive selection	2430993
14117897	14117920	19	+	25494202	A375	resistance to PLX-4720 (puromycin)	CGGCCATTCACTCGCTCGCGAGG	PRKACA	ENSG00000072062	0.16882058402478295	[14,18]	[4,1]	0	dCas9-VP64	positive selection	2430994
14117845	14117868	19	-	25494202	A375	resistance to PLX-4720 (puromycin)	GAGCCTATAGTGGCGCGGGAAGG	PRKACA	ENSG00000072062	-1.4723335219633777	[119,28]	[7,1]	-8	dCas9-VP64	positive selection	2430995
14104796	14104819	19	-	25494202	A375	resistance to PLX-4720 (puromycin)	TCACTACAACCTCTGCCTCCGGG	PRKACA	ENSG00000072062	0.3736894149735144	[619,564]	[67,277]	1	dCas9-VP64	positive selection	2444008
14103872	14103895	19	-	25494202	A375	resistance to PLX-4720 (puromycin)	GGGGTCTCGCTACATTGCCCAGG	PRKACA	ENSG00000072062	0.300287162092	[67,8]	[8,10]	1	dCas9-VP64	positive selection	2467349
14105282	14105305	19	+	25494202	A375	resistance to PLX-4720 (puromycin)	CGGGCGGATTACCTGAGGTCAGG	PRKACA	ENSG00000072062	0.5226490937601747	[40,1]	[8,2]	2	dCas9-VP64	positive selection	2470441
14114342	14114365	19	+	25494202	A375	resistance to PLX-4720 (puromycin)	CCTCCGAGTTTCTGTAGACGCGG	PRKACA	ENSG00000072062	0.3858799280734475	[307,66]	[91,10]	1	dCas9-VP64	positive selection	2478118
14114288	14114311	19	+	25494202	A375	resistance to PLX-4720 (puromycin)	GGAAGAGAAACCCAACCCAGAGG	PRKACA	ENSG00000072062	-0.31259242056169323	[17,26]	[3,2]	-1	dCas9-VP64	positive selection	2478119
14114311	14114334	19	-	25494202	A375	resistance to PLX-4720 (puromycin)	TGTCCCTCCTCCACACCCAGTGG	PRKACA	ENSG00000072062	-0.4124010504527924	[63,112]	[8,19]	-2	dCas9-VP64	positive selection	2478120
14117869	14117892	19	+	25494202	A375	resistance to PLX-4720 (zeocin)	CAGCCTCGGGACACGCACCGCGG	PRKACA	ENSG00000072062	-0.38519243256821656	[14,48]	[5,8]	-4	dCas9-VP64	positive selection	2526248
14117897	14117920	19	+	25494202	A375	resistance to PLX-4720 (zeocin)	CGGCCATTCACTCGCTCGCGAGG	PRKACA	ENSG00000072062	-0.7162784603372107	[77,45]	[12,10]	-7	dCas9-VP64	positive selection	2526249
14117845	14117868	19	-	25494202	A375	resistance to PLX-4720 (zeocin)	GAGCCTATAGTGGCGCGGGAAGG	PRKACA	ENSG00000072062	-2.170434918379383	[495,164]	[13,32]	-9	dCas9-VP64	positive selection	2526250
14104796	14104819	19	-	25494202	A375	resistance to PLX-4720 (zeocin)	TCACTACAACCTCTGCCTCCGGG	PRKACA	ENSG00000072062	2.2699980135687987	[309,268]	[879,61]	8	dCas9-VP64	positive selection	2539263
14103872	14103895	19	-	25494202	A375	resistance to PLX-4720 (zeocin)	GGGGTCTCGCTACATTGCCCAGG	PRKACA	ENSG00000072062	5.267466340144677	[90,283]	[372,4192]	9	dCas9-VP64	positive selection	2562604
14105282	14105305	19	+	25494202	A375	resistance to PLX-4720 (zeocin)	CGGGCGGATTACCTGAGGTCAGG	PRKACA	ENSG00000072062	0.40867490627340075	[18,31]	[6,13]	3	dCas9-VP64	positive selection	2565696
14114342	14114365	19	+	25494202	A375	resistance to PLX-4720 (zeocin)	CCTCCGAGTTTCTGTAGACGCGG	PRKACA	ENSG00000072062	4.013520332948347	[90,60]	[806,28]	9	dCas9-VP64	positive selection	2573373
14114288	14114311	19	+	25494202	A375	resistance to PLX-4720 (zeocin)	GGAAGAGAAACCCAACCCAGAGG	PRKACA	ENSG00000072062	2.2675341328986445	[10,8]	[24,7]	8	dCas9-VP64	positive selection	2573374
14114311	14114334	19	-	25494202	A375	resistance to PLX-4720 (zeocin)	TGTCCCTCCTCCACACCCAGTGG	PRKACA	ENSG00000072062	-0.2805013251591879	[69,123]	[28,21]	-3	dCas9-VP64	positive selection	2573375
14100840	14100863	19	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	AGATGTTCTCACACCTACGGCGG	PRKACA	ENSG00000072062	-0.43067962761798034	[3,2]	[3,0]	-6	hSpCas9	positive selection	3013619
14102822	14102845	19	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	AGGAGAACTCGAGTTTGACGAGG	PRKACA	ENSG00000072062	0.22747321687330987	[2,2]	[3,2]	5	hSpCas9	positive selection	3013620
14097865	14097888	19	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCCCCATGCCCGTTTCTACGCGG	PRKACA	ENSG00000072062	-0.17237212401433716	[2,2]	[2,0]	-2	hSpCas9	positive selection	3013621
14100887	14100910	19	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GGACAACTCAAACTTATACATGG	PRKACA	ENSG00000072062	0.34645471679021256	[5,5]	[6,5]	7	hSpCas9	positive selection	3013622
14100840	14100863	19	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	AGATGTTCTCACACCTACGGCGG	PRKACA	ENSG00000072062	0.41408982513751336	[3,3]	[3,2]	7	hSpCas9	positive selection	3081477
14102822	14102845	19	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	AGGAGAACTCGAGTTTGACGAGG	PRKACA	ENSG00000072062	-0.1861363250321397	[2,2]	[3,0]	-3	hSpCas9	positive selection	3081478
14097865	14097888	19	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCCCCATGCCCGTTTCTACGCGG	PRKACA	ENSG00000072062	0.21948997576945448	[2,2]	[3,1]	4	hSpCas9	positive selection	3081479
14100887	14100910	19	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GGACAACTCAAACTTATACATGG	PRKACA	ENSG00000072062	0.23141998177816997	[5,5]	[4,4]	4	hSpCas9	positive selection	3081480
14117520	14117543		-	24336571	A375	resistance to PLX after 7 days	CAACGCCGCCGCCGCCAAGAAGG	PRKACA	ENSG00000072062	0.09166438131218912	[5,5]	[6,6]	3	hSpCas9	positive selection	3137740
14106858	14106881		+	24336571	A375	resistance to PLX after 7 days	TTCGTTCAAACTGATCCAAGTGG	PRKACA	ENSG00000072062	0.14284336609963852	[11,12]	[12,14]	4	hSpCas9	positive selection	3137741
14107366	14107389		+	24336571	A375	resistance to PLX after 7 days	TTTTTTAAGAAAATCTTCTTTGG	PRKACA	ENSG00000072062	-0.2158763035271826	[12,11]	[9,11]	-6	hSpCas9	positive selection	3137742
14117520	14117543		-	24336571	A375	resistance to PLX after 14 days	CAACGCCGCCGCCGCCAAGAAGG	PRKACA	ENSG00000072062	0.9526169827061981	[5,5]	[3,5]	7	hSpCas9	positive selection	3195533
14106858	14106881		+	24336571	A375	resistance to PLX after 14 days	TTCGTTCAAACTGATCCAAGTGG	PRKACA	ENSG00000072062	0.30205731198513097	[10,10]	[6,4]	3	hSpCas9	positive selection	3195534
14107366	14107389		+	24336571	A375	resistance to PLX after 14 days	TTTTTTAAGAAAATCTTCTTTGG	PRKACA	ENSG00000072062	-0.23530969033717328	[15,12]	[3,6]	-3	hSpCas9	positive selection	3195535
14117520	14117543		-	24336571	A375	viability after 7 days	CAACGCCGCCGCCGCCAAGAAGG	PRKACA	ENSG00000072062	-0.2961824313036403	[7]	[5,5]	-4	hSpCas9	negative selection	3253326
14106858	14106881		+	24336571	A375	viability after 7 days	TTCGTTCAAACTGATCCAAGTGG	PRKACA	ENSG00000072062	-0.2150865485407511	[15]	[11,12]	-3	hSpCas9	negative selection	3253327
14107366	14107389		+	24336571	A375	viability after 7 days	TTTTTTAAGAAAATCTTCTTTGG	PRKACA	ENSG00000072062	-0.7736562763098084	[23]	[12,11]	-8	hSpCas9	negative selection	3253328
14117520	14117543		-	24336571	A375	viability after 14 days	CAACGCCGCCGCCGCCAAGAAGG	PRKACA	ENSG00000072062	-0.40891796338257436	[7]	[5,5]	-5	hSpCas9	negative selection	3311119
14106858	14106881		+	24336571	A375	viability after 14 days	TTCGTTCAAACTGATCCAAGTGG	PRKACA	ENSG00000072062	-0.42016758947391564	[15]	[10,10]	-5	hSpCas9	negative selection	3311120
14107366	14107389		+	24336571	A375	viability after 14 days	TTTTTTAAGAAAATCTTCTTTGG	PRKACA	ENSG00000072062	-0.6305806275269357	[23]	[15,12]	-6	hSpCas9	negative selection	3311121
14117506	14117529	19	+	27383988	293T	resistance to West Nile virus (flavivirus)	CTCCTGCTCGCTGCCCTTCTTGG	PRKACA	ENSG00000072062	-2.208240193363564	[706,706]	[0,0]	-9	hSpCas9	positive selection	3387449
14106759	14106782	19	-	27383988	293T	resistance to West Nile virus (flavivirus)	GAAGATCCTCGACAAACAGAAGG	PRKACA	ENSG00000072062	0.36250844813789157	[118,118]	[0,0]	2	hSpCas9	positive selection	3387450
14106858	14106881	19	+	27383988	293T	resistance to West Nile virus (flavivirus)	TTCGTTCAAACTGATCCAAGTGG	PRKACA	ENSG00000072062	-0.7426737885541649	[255,255]	[0,0]	-5	hSpCas9	positive selection	3387451
14100840	14100863	19	-	26780180	HT29	viability (Avana library 4 designs)	AGATGTTCTCACACCTACGGCGG	PRKACA	ENSG00000072062	2.12109491886767	[]	[]	7	hSpCas9	negative selection	3451804
14102821	14102844	19	+	26780180	HT29	viability (Avana library 4 designs)	AGGAGAACTCGAGTTTGACGAGG	PRKACA	ENSG00000072062	1.67144681847273	[]	[]	6	hSpCas9	negative selection	3451805
14097865	14097888	19	-	26780180	HT29	viability (Avana library 4 designs)	GCCCCATGCCCGTTTCTACGCGG	PRKACA	ENSG00000072062	1.62000791473441	[]	[]	6	hSpCas9	negative selection	3451806
14100887	14100910	19	-	26780180	HT29	viability (Avana library 4 designs)	GGACAACTCAAACTTATACATGG	PRKACA	ENSG00000072062	0.0600985622289605	[]	[]	0	hSpCas9	negative selection	3451807
14097865	14097888	19	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCCCCATGCCCGTTTCTACGCGG	PRKACA	ENSG00000072062	-2.95727447337248	[]	[]	-4	hSpCas9	negative selection	3547876
14100840	14100863	19	-	26780180	A375	viability (Avana lentiCRISPRv2)	AGATGTTCTCACACCTACGGCGG	PRKACA	ENSG00000072062	-3.51465700571361	[]	[]	-4	hSpCas9	negative selection	3547877
14100887	14100910	19	-	26780180	A375	viability (Avana lentiCRISPRv2)	GGACAACTCAAACTTATACATGG	PRKACA	ENSG00000072062	-7.20421361014461	[]	[]	-6	hSpCas9	negative selection	3547878
14102821	14102844	19	+	26780180	A375	viability (Avana lentiCRISPRv2)	AGGAGAACTCGAGTTTGACGAGG	PRKACA	ENSG00000072062	1.86971563822756	[]	[]	2	hSpCas9	negative selection	3547879
14097811	14097834	19	-	26780180	A375	viability (Avana lentiCRISPRv2)	CTCGCTGGATCTCATCTACAGGG	PRKACA	ENSG00000072062	1.91955672253722	[]	[]	2	hSpCas9	negative selection	3547880
14097774	14097797	19	-	26780180	A375	viability (Avana lentiCRISPRv2)	AATCTGCTCATTGACCAGCAGGG	PRKACA	ENSG00000072062	0.0187504332904891	[]	[]	0	hSpCas9	negative selection	3547881
14097865	14097888	19	-	26780180	A375	viability (Avana lentiGuide)	GCCCCATGCCCGTTTCTACGCGG	PRKACA	ENSG00000072062	-3.63489795748771	[]	[]	-6	hSpCas9	negative selection	3656535
14100840	14100863	19	-	26780180	A375	viability (Avana lentiGuide)	AGATGTTCTCACACCTACGGCGG	PRKACA	ENSG00000072062	1.41259575260959	[]	[]	1	hSpCas9	negative selection	3656536
14100887	14100910	19	-	26780180	A375	viability (Avana lentiGuide)	GGACAACTCAAACTTATACATGG	PRKACA	ENSG00000072062	-1.10067491111525	[]	[]	-2	hSpCas9	negative selection	3656537
14102821	14102844	19	+	26780180	A375	viability (Avana lentiGuide)	AGGAGAACTCGAGTTTGACGAGG	PRKACA	ENSG00000072062	2.3330665865811	[]	[]	2	hSpCas9	negative selection	3656538
14097811	14097834	19	-	26780180	A375	viability (Avana lentiGuide)	CTCGCTGGATCTCATCTACAGGG	PRKACA	ENSG00000072062	-0.403722005098819	[]	[]	0	hSpCas9	negative selection	3656539
14097774	14097797	19	-	26780180	A375	viability (Avana lentiGuide)	AATCTGCTCATTGACCAGCAGGG	PRKACA	ENSG00000072062	1.62939705097324	[]	[]	1	hSpCas9	negative selection	3656540
14097865	14097888	19	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCCCCATGCCCGTTTCTACGCGG	PRKACA	ENSG00000072062	0.18591888986015034	[4]	[5,3]	5	hSpCas9	positive selection	3765142
14100840	14100863	19	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AGATGTTCTCACACCTACGGCGG	PRKACA	ENSG00000072062	-0.30964207595897886	[4]	[5,2]	-5	hSpCas9	positive selection	3765143
14100887	14100910	19	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGACAACTCAAACTTATACATGG	PRKACA	ENSG00000072062	-0.8091011363190967	[7]	[4,2]	-8	hSpCas9	positive selection	3765144
14102821	14102844	19	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AGGAGAACTCGAGTTTGACGAGG	PRKACA	ENSG00000072062	0.19347465039624331	[4]	[4,5]	5	hSpCas9	positive selection	3765145
14097811	14097834	19	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CTCGCTGGATCTCATCTACAGGG	PRKACA	ENSG00000072062	0.1777808239616982	[4]	[5,5]	5	hSpCas9	positive selection	3765146
14097774	14097797	19	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AATCTGCTCATTGACCAGCAGGG	PRKACA	ENSG00000072062	0.1460212133930045	[6]	[6,7]	4	hSpCas9	positive selection	3765147
14097865	14097888	19	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCCCCATGCCCGTTTCTACGCGG	PRKACA	ENSG00000072062	-0.13105994572861432	[4]	[1,4]	-2	hSpCas9	positive selection	3873749
14100840	14100863	19	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AGATGTTCTCACACCTACGGCGG	PRKACA	ENSG00000072062	-2.3096430393102403	[4]	[0,0]	-9	hSpCas9	positive selection	3873750
14100887	14100910	19	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGACAACTCAAACTTATACATGG	PRKACA	ENSG00000072062	0.24011542036379438	[6]	[6,6]	6	hSpCas9	positive selection	3873751
14102821	14102844	19	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AGGAGAACTCGAGTTTGACGAGG	PRKACA	ENSG00000072062	0.025905454948950496	[4]	[4,3]	0	hSpCas9	positive selection	3873752
14097811	14097834	19	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CTCGCTGGATCTCATCTACAGGG	PRKACA	ENSG00000072062	0.4184033665872308	[5]	[6,6]	9	hSpCas9	positive selection	3873753
14097774	14097797	19	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AATCTGCTCATTGACCAGCAGGG	PRKACA	ENSG00000072062	0.15599204894691626	[6]	[5,6]	3	hSpCas9	positive selection	3873754
14117520	14117543	19	-	26780180	A375	viability	CAACGCCGCCGCCGCCAAGAAGG	PRKACA	ENSG00000072062	1.08413284490143	[]	[]	5	hSpCas9	negative selection	3984201
14117506	14117529	19	+	26780180	A375	viability	CTCCTGCTCGCTGCCCTTCTTGG	PRKACA	ENSG00000072062	-0.343778758001626	[]	[]	-8	hSpCas9	negative selection	3984202
14106778	14106801	19	+	26780180	A375	viability	CTTCATGGCATAGTGGTTCCCGG	PRKACA	ENSG00000072062	0.775284873108066	[]	[]	3	hSpCas9	negative selection	3984203
14106759	14106782	19	-	26780180	A375	viability	GAAGATCCTCGACAAACAGAAGG	PRKACA	ENSG00000072062	1.17412129465112	[]	[]	6	hSpCas9	negative selection	3984204
14106858	14106881	19	+	26780180	A375	viability	TTCGTTCAAACTGATCCAAGTGG	PRKACA	ENSG00000072062	1.64774936843953	[]	[]	8	hSpCas9	negative selection	3984205
14106845	14106868	19	-	26780180	A375	viability	TTTGAACGAATCAAGACCCTCGG	PRKACA	ENSG00000072062	1.99020411179595	[]	[]	9	hSpCas9	negative selection	3984206
14117520	14117543	19	-	26780180	HT29	viability (GeCKOv2 library)	CAACGCCGCCGCCGCCAAGAAGG	PRKACA	ENSG00000072062	1.34125313887292	[]	[]	6	hSpCas9	negative selection	4092167
14117506	14117529	19	+	26780180	HT29	viability (GeCKOv2 library)	CTCCTGCTCGCTGCCCTTCTTGG	PRKACA	ENSG00000072062	-0.24793155733598	[]	[]	-6	hSpCas9	negative selection	4092168
14106778	14106801	19	+	26780180	HT29	viability (GeCKOv2 library)	CTTCATGGCATAGTGGTTCCCGG	PRKACA	ENSG00000072062	1.11867133012536	[]	[]	5	hSpCas9	negative selection	4092169
14106759	14106782	19	-	26780180	HT29	viability (GeCKOv2 library)	GAAGATCCTCGACAAACAGAAGG	PRKACA	ENSG00000072062	0.24271973256271	[]	[]	0	hSpCas9	negative selection	4092170
14106858	14106881	19	+	26780180	HT29	viability (GeCKOv2 library)	TTCGTTCAAACTGATCCAAGTGG	PRKACA	ENSG00000072062	0.294011172518685	[]	[]	0	hSpCas9	negative selection	4092171
14106845	14106868	19	-	26780180	HT29	viability (GeCKOv2 library)	TTTGAACGAATCAAGACCCTCGG	PRKACA	ENSG00000072062	1.63290033382384	[]	[]	8	hSpCas9	negative selection	4092172
14117520	14117543	19	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CAACGCCGCCGCCGCCAAGAAGG	PRKACA	ENSG00000072062	0.20956932235436973	[2]	[1,2]	5	hSpCas9	positive selection	4162895
14106858	14106881	19	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TTCGTTCAAACTGATCCAAGTGG	PRKACA	ENSG00000072062	0.12317840403706212	[3]	[2,2]	3	hSpCas9	positive selection	4162896
14107366	14107389	19	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TTTTTTAAGAAAATCTTCTTTGG	PRKACA	ENSG00000072062	0.06872040646991572	[3]	[2,2]	1	hSpCas9	positive selection	4162897
14117520	14117543	19	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CAACGCCGCCGCCGCCAAGAAGG	PRKACA	ENSG00000072062	0.405182749210091	[2]	[1,1,4,0]	3	hSpCas9	positive selection	4226917
14106858	14106881	19	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TTCGTTCAAACTGATCCAAGTGG	PRKACA	ENSG00000072062	-0.25514563372681354	[4]	[0,2,2,0]	-4	hSpCas9	positive selection	4226918
14107366	14107389	19	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TTTTTTAAGAAAATCTTCTTTGG	PRKACA	ENSG00000072062	1.1040175760678657	[3]	[3,5,1,3]	8	hSpCas9	positive selection	4226919
14117520	14117543	19	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CAACGCCGCCGCCGCCAAGAAGG	PRKACA	ENSG00000072062	-0.05232018141914874	[1]	[1,0]	-1	hSpCas9	positive selection	4292138
14106845	14106868	19	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TTTGAACGAATCAAGACCCTCGG	PRKACA	ENSG00000072062	-0.1947313220679596	[2]	[2,1]	-4	hSpCas9	positive selection	4292139
14106778	14106801	19	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CTTCATGGCATAGTGGTTCCCGG	PRKACA	ENSG00000072062	0.08190303740854445	[3]	[3,1]	1	hSpCas9	positive selection	4292140
14117506	14117529	19	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CTCCTGCTCGCTGCCCTTCTTGG	PRKACA	ENSG00000072062	0.4054605448370323	[4]	[5,4]	8	hSpCas9	positive selection	4356396
14106759	14106782	19	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GAAGATCCTCGACAAACAGAAGG	PRKACA	ENSG00000072062	0.4460968144656714	[2]	[2,2]	8	hSpCas9	positive selection	4356397
14106858	14106881	19	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TTCGTTCAAACTGATCCAAGTGG	PRKACA	ENSG00000072062	-0.08268010634344533	[3]	[2,2]	-2	hSpCas9	positive selection	4356398
14097828	14097850	19	+	27760321	OCIAML3	viability	AGCGAGTGCAGATACTCAAAGG	PRKACA	ENSG00000072062	0.10993604527359446	[174,149]	[134,138]	1	hSpCas9	negative selection	4430546
14100831	14100853	19	-	27760321	OCIAML3	viability	ACACCTACGGCGGATCGGAAGG	PRKACA	ENSG00000072062	-0.3419263686168182	[771,719]	[430,498]	-4	hSpCas9	negative selection	4430547
14100887	14100909	19	-	27760321	OCIAML3	viability	GACAACTCAAACTTATACATGG	PRKACA	ENSG00000072062	-0.18241462519118556	[13,14]	[16,0]	-2	hSpCas9	negative selection	4430548
14102811	14102833	19	-	27760321	OCIAML3	viability	TCGAGTTCTCCTTCAAGGTGGG	PRKACA	ENSG00000072062	-0.5520812297366525	[479,369]	[109,374]	-5	hSpCas9	negative selection	4430549
14106859	14106881	19	+	27760321	OCIAML3	viability	TCGTTCAAACTGATCCAAGTGG	PRKACA	ENSG00000072062	-0.2674003583697494	[287,239]	[195,137]	-3	hSpCas9	negative selection	4430550
14097828	14097850	19	+	27760321	OCIAML2	viability	AGCGAGTGCAGATACTCAAAGG	PRKACA	ENSG00000072062	-0.348201675208788	[174,149]	[67,148]	-4	hSpCas9	negative selection	4514009
14100831	14100853	19	-	27760321	OCIAML2	viability	ACACCTACGGCGGATCGGAAGG	PRKACA	ENSG00000072062	0.20743353094088446	[771,719]	[640,770]	2	hSpCas9	negative selection	4514010
14100887	14100909	19	-	27760321	OCIAML2	viability	GACAACTCAAACTTATACATGG	PRKACA	ENSG00000072062	-3.5609209966487487	[13,14]	[0,0]	-9	hSpCas9	negative selection	4514011
14102811	14102833	19	-	27760321	OCIAML2	viability	TCGAGTTCTCCTTCAAGGTGGG	PRKACA	ENSG00000072062	-1.2638261494139469	[479,369]	[123,165]	-8	hSpCas9	negative selection	4514012
14106859	14106881	19	+	27760321	OCIAML2	viability	TCGTTCAAACTGATCCAAGTGG	PRKACA	ENSG00000072062	-0.09617488519853223	[287,239]	[204,190]	-1	hSpCas9	negative selection	4514013
14097828	14097850	19	+	27760321	MV411	viability	AGCGAGTGCAGATACTCAAAGG	PRKACA	ENSG00000072062	-5.8927736789390925	[174,149]	[0,2]	-9	hSpCas9	negative selection	4597472
14100831	14100853	19	-	27760321	MV411	viability	ACACCTACGGCGGATCGGAAGG	PRKACA	ENSG00000072062	-0.5538408911022709	[771,719]	[201,535]	-4	hSpCas9	negative selection	4597473
14100887	14100909	19	-	27760321	MV411	viability	GACAACTCAAACTTATACATGG	PRKACA	ENSG00000072062	1.9096570419709193	[13,14]	[0,88]	9	hSpCas9	negative selection	4597474
14102811	14102833	19	-	27760321	MV411	viability	TCGAGTTCTCCTTCAAGGTGGG	PRKACA	ENSG00000072062	-3.8584277522629726	[479,369]	[11,29]	-9	hSpCas9	negative selection	4597475
14106859	14106881	19	+	27760321	MV411	viability	TCGTTCAAACTGATCCAAGTGG	PRKACA	ENSG00000072062	-0.31355044001662036	[287,239]	[135,144]	-2	hSpCas9	negative selection	4597476
14097828	14097850	19	+	27760321	HL60	viability	AGCGAGTGCAGATACTCAAAGG	PRKACA	ENSG00000072062	-0.5247438720457256	[174,149]	[74,109]	-5	hSpCas9	negative selection	4680935
14100831	14100853	19	-	27760321	HL60	viability	ACACCTACGGCGGATCGGAAGG	PRKACA	ENSG00000072062	0.16704221024669919	[771,719]	[683,684]	2	hSpCas9	negative selection	4680936
14100887	14100909	19	-	27760321	HL60	viability	GACAACTCAAACTTATACATGG	PRKACA	ENSG00000072062	-1.737741772623413	[13,14]	[5,0]	-9	hSpCas9	negative selection	4680937
14102811	14102833	19	-	27760321	HL60	viability	TCGAGTTCTCCTTCAAGGTGGG	PRKACA	ENSG00000072062	-1.385267153797748	[479,369]	[112,151]	-8	hSpCas9	negative selection	4680938
14106859	14106881	19	+	27760321	HL60	viability	TCGTTCAAACTGATCCAAGTGG	PRKACA	ENSG00000072062	-0.4897094952256914	[287,239]	[150,154]	-5	hSpCas9	negative selection	4680939
14097828	14097850	19	+	27760321	HT1080	viability	AGCGAGTGCAGATACTCAAAGG	PRKACA	ENSG00000072062	2.816794512439769	[149,116]	[631,92]	9	hSpCas9	negative selection	4764398
14100831	14100853	19	-	27760321	HT1080	viability	ACACCTACGGCGGATCGGAAGG	PRKACA	ENSG00000072062	1.5726281008521177	[719,561]	[1002,492]	8	hSpCas9	negative selection	4764399
14100887	14100909	19	-	27760321	HT1080	viability	GACAACTCAAACTTATACATGG	PRKACA	ENSG00000072062	-2.429279739642115	[14,11]	[0,0]	-7	hSpCas9	negative selection	4764400
14102811	14102833	19	-	27760321	HT1080	viability	TCGAGTTCTCCTTCAAGGTGGG	PRKACA	ENSG00000072062	-0.46949884237528905	[369,288]	[174,6]	-2	hSpCas9	negative selection	4764401
14106859	14106881	19	+	27760321	HT1080	viability	TCGTTCAAACTGATCCAAGTGG	PRKACA	ENSG00000072062	2.4339638980067795	[239,186]	[681,215]	9	hSpCas9	negative selection	4764402
14097828	14097850	19	+	27760321	HT29	viability after 7 days	AGCGAGTGCAGATACTCAAAGG	PRKACA	ENSG00000072062	-0.21003661798437245	[149,116]	[120,138,179]	-3	hSpCas9	negative selection	4847861
14100831	14100853	19	-	27760321	HT29	viability after 7 days	ACACCTACGGCGGATCGGAAGG	PRKACA	ENSG00000072062	-0.5041287192823348	[719,561]	[810,534,433]	-6	hSpCas9	negative selection	4847862
14100887	14100909	19	-	27760321	HT29	viability after 7 days	GACAACTCAAACTTATACATGG	PRKACA	ENSG00000072062	-2.047103830657269	[14,11]	[0,1,8]	-9	hSpCas9	negative selection	4847863
14102811	14102833	19	-	27760321	HT29	viability after 7 days	TCGAGTTCTCCTTCAAGGTGGG	PRKACA	ENSG00000072062	-0.33752341962389265	[369,288]	[321,330,349]	-5	hSpCas9	negative selection	4847864
14106859	14106881	19	+	27760321	HT29	viability after 7 days	TCGTTCAAACTGATCCAAGTGG	PRKACA	ENSG00000072062	-0.47741190334995254	[239,186]	[238,220,138]	-6	hSpCas9	negative selection	4847865
14097828	14097850	19	+	27760321	HT29	viability after 25 days	AGCGAGTGCAGATACTCAAAGG	PRKACA	ENSG00000072062	0.1354194128780648	[149,116]	[119,152,239]	1	hSpCas9	negative selection	4931324
14100831	14100853	19	-	27760321	HT29	viability after 25 days	ACACCTACGGCGGATCGGAAGG	PRKACA	ENSG00000072062	-0.04481311850241054	[719,561]	[558,730,864]	0	hSpCas9	negative selection	4931325
14100887	14100909	19	-	27760321	HT29	viability after 25 days	GACAACTCAAACTTATACATGG	PRKACA	ENSG00000072062	-1.1389643901022586	[14,11]	[0,16,2]	-7	hSpCas9	negative selection	4931326
14102811	14102833	19	-	27760321	HT29	viability after 25 days	TCGAGTTCTCCTTCAAGGTGGG	PRKACA	ENSG00000072062	-0.57992273887301	[369,288]	[229,229,301]	-5	hSpCas9	negative selection	4931327
14106859	14106881	19	+	27760321	HT29	viability after 25 days	TCGTTCAAACTGATCCAAGTGG	PRKACA	ENSG00000072062	0.17567293184425736	[239,186]	[354,235,224]	1	hSpCas9	negative selection	4931328
14097828	14097850	19	+	27760321	HT29	viability after 22 days	AGCGAGTGCAGATACTCAAAGG	PRKACA	ENSG00000072062	0.2905747298560095	[149,116]	[92,63,413]	3	hSpCas9	negative selection	5014787
14100831	14100853	19	-	27760321	HT29	viability after 22 days	ACACCTACGGCGGATCGGAAGG	PRKACA	ENSG00000072062	-0.2547850369379012	[719,561]	[504,668,692]	-3	hSpCas9	negative selection	5014788
14100887	14100909	19	-	27760321	HT29	viability after 22 days	GACAACTCAAACTTATACATGG	PRKACA	ENSG00000072062	-0.9736405385994304	[14,11]	[0,21,0]	-6	hSpCas9	negative selection	5014789
14102811	14102833	19	-	27760321	HT29	viability after 22 days	TCGAGTTCTCCTTCAAGGTGGG	PRKACA	ENSG00000072062	-0.43672132923107276	[369,288]	[350,254,235]	-4	hSpCas9	negative selection	5014790
14106859	14106881	19	+	27760321	HT29	viability after 22 days	TCGTTCAAACTGATCCAAGTGG	PRKACA	ENSG00000072062	-0.21990667179907175	[239,186]	[162,158,315]	-2	hSpCas9	negative selection	5014791
14097828	14097850	19	+	27760321	HT29	viability after 19 days	AGCGAGTGCAGATACTCAAAGG	PRKACA	ENSG00000072062	0.16793283047727825	[149,116]	[256,244,26]	1	hSpCas9	negative selection	5098250
14100831	14100853	19	-	27760321	HT29	viability after 19 days	ACACCTACGGCGGATCGGAAGG	PRKACA	ENSG00000072062	0.1651104225481097	[719,561]	[1066,787,642]	1	hSpCas9	negative selection	5098251
14100887	14100909	19	-	27760321	HT29	viability after 19 days	GACAACTCAAACTTATACATGG	PRKACA	ENSG00000072062	-3.5131785501033583	[14,11]	[0,0,1]	-9	hSpCas9	negative selection	5098252
14102811	14102833	19	-	27760321	HT29	viability after 19 days	TCGAGTTCTCCTTCAAGGTGGG	PRKACA	ENSG00000072062	-1.5017383634472348	[369,288]	[151,58,187]	-7	hSpCas9	negative selection	5098253
14106859	14106881	19	+	27760321	HT29	viability after 19 days	TCGTTCAAACTGATCCAAGTGG	PRKACA	ENSG00000072062	-0.14460103537195323	[239,186]	[213,260,187]	-1	hSpCas9	negative selection	5098254
14097828	14097850	19	+	27760321	HT29	viability after 16 days	AGCGAGTGCAGATACTCAAAGG	PRKACA	ENSG00000072062	0.3485286683262596	[149,116]	[168,169,229]	4	hSpCas9	negative selection	5181713
14100831	14100853	19	-	27760321	HT29	viability after 16 days	ACACCTACGGCGGATCGGAAGG	PRKACA	ENSG00000072062	-0.5027873620483647	[719,561]	[461,587,461]	-5	hSpCas9	negative selection	5181714
14100887	14100909	19	-	27760321	HT29	viability after 16 days	GACAACTCAAACTTATACATGG	PRKACA	ENSG00000072062	-2.655912366974758	[14,11]	[0,4,0]	-8	hSpCas9	negative selection	5181715
14102811	14102833	19	-	27760321	HT29	viability after 16 days	TCGAGTTCTCCTTCAAGGTGGG	PRKACA	ENSG00000072062	-0.9995026357348343	[369,288]	[79,233,227]	-7	hSpCas9	negative selection	5181716
14106859	14106881	19	+	27760321	HT29	viability after 16 days	TCGTTCAAACTGATCCAAGTGG	PRKACA	ENSG00000072062	-0.22142313333255503	[239,186]	[178,131,302]	-2	hSpCas9	negative selection	5181717
14097828	14097850	19	+	27760321	HT29	viability after 13 days	AGCGAGTGCAGATACTCAAAGG	PRKACA	ENSG00000072062	-0.795475931562581	[149,116]	[136,82,49]	-7	hSpCas9	negative selection	5265176
14100831	14100853	19	-	27760321	HT29	viability after 13 days	ACACCTACGGCGGATCGGAAGG	PRKACA	ENSG00000072062	-0.32778641554885535	[719,561]	[803,603,381]	-4	hSpCas9	negative selection	5265177
14100887	14100909	19	-	27760321	HT29	viability after 13 days	GACAACTCAAACTTATACATGG	PRKACA	ENSG00000072062	-1.2650900772906564	[14,11]	[0,1,15]	-8	hSpCas9	negative selection	5265178
14102811	14102833	19	-	27760321	HT29	viability after 13 days	TCGAGTTCTCCTTCAAGGTGGG	PRKACA	ENSG00000072062	-0.31511105818034146	[369,288]	[340,227,349]	-4	hSpCas9	negative selection	5265179
14106859	14106881	19	+	27760321	HT29	viability after 13 days	TCGTTCAAACTGATCCAAGTGG	PRKACA	ENSG00000072062	-0.17427253122021824	[239,186]	[240,157,256]	-2	hSpCas9	negative selection	5265180
14097828	14097850	19	+	27760321	HT29	viability after 10 days	AGCGAGTGCAGATACTCAAAGG	PRKACA	ENSG00000072062	-0.013883361944861283	[149,116]	[226,72,191]	0	hSpCas9	negative selection	5348639
14100831	14100853	19	-	27760321	HT29	viability after 10 days	ACACCTACGGCGGATCGGAAGG	PRKACA	ENSG00000072062	-0.0031154814702056832	[719,561]	[820,774,798]	0	hSpCas9	negative selection	5348640
14100887	14100909	19	-	27760321	HT29	viability after 10 days	GACAACTCAAACTTATACATGG	PRKACA	ENSG00000072062	0.7017387794702739	[14,11]	[0,51,29]	8	hSpCas9	negative selection	5348641
14102811	14102833	19	-	27760321	HT29	viability after 10 days	TCGAGTTCTCCTTCAAGGTGGG	PRKACA	ENSG00000072062	-0.7011041128649235	[369,288]	[274,139,338]	-7	hSpCas9	negative selection	5348642
14106859	14106881	19	+	27760321	HT29	viability after 10 days	TCGTTCAAACTGATCCAAGTGG	PRKACA	ENSG00000072062	0.3304939845968546	[239,186]	[356,316,330]	4	hSpCas9	negative selection	5348643
14097828	14097850	19	+	27760321	MOLM13	viability	AGCGAGTGCAGATACTCAAAGG	PRKACA	ENSG00000072062	0.699005195705431	[174,149]	[1,272]	5	hSpCas9	negative selection	5432102
14100831	14100853	19	-	27760321	MOLM13	viability	ACACCTACGGCGGATCGGAAGG	PRKACA	ENSG00000072062	-0.753838427190335	[771,719]	[172,314]	-5	hSpCas9	negative selection	5432103
14100887	14100909	19	-	27760321	MOLM13	viability	GACAACTCAAACTTATACATGG	PRKACA	ENSG00000072062	-3.041040249641423	[13,14]	[0,0]	-9	hSpCas9	negative selection	5432104
14102811	14102833	19	-	27760321	MOLM13	viability	TCGAGTTCTCCTTCAAGGTGGG	PRKACA	ENSG00000072062	-0.4393818722896382	[479,369]	[6,318]	-3	hSpCas9	negative selection	5432105
14106859	14106881	19	+	27760321	MOLM13	viability	TCGTTCAAACTGATCCAAGTGG	PRKACA	ENSG00000072062	0.4077859567848287	[287,239]	[145,239]	3	hSpCas9	negative selection	5432106
14117239	14117262	19	+	27661255	K562	viability	GCGGTCATACGTGCCATGGTTGG	PRKACA	ENSG00000072062	0.05668983449367182	[420,409]	[380,314]	2	dCas9-KRAB	negative selection	5504112
14117312	14117335	19	+	27661255	K562	viability	GGGAAGGGGACCCCTACAGGGGG	PRKACA	ENSG00000072062	0.005523357226757786	[1125,1273]	[1039,891]	0	dCas9-KRAB	negative selection	5504113
14117460	14117483	19	+	27661255	K562	viability	GCAGCGCAGGGCCAAGATCGGGG	PRKACA	ENSG00000072062	0.8526832382278613	[7,7]	[10,11]	9	dCas9-KRAB	negative selection	5504114
14117520	14117543	19	-	27260156	BXPC3	viability	CAACGCCGCCGCCGCCAAGAAGG	PRKACA	ENSG00000072062	0.24771743950198122	[123]	[179,210,116,91]	5	hSpCas9	negative selection	5564598
14106845	14106868	19	-	27260156	BXPC3	viability	TTTGAACGAATCAAGACCCTCGG	PRKACA	ENSG00000072062	-0.17866130804807878	[451]	[346,475,403,447]	-4	hSpCas9	negative selection	5564599
14106778	14106801	19	+	27260156	BXPC3	viability	CTTCATGGCATAGTGGTTCCCGG	PRKACA	ENSG00000072062	0.0899542322831623	[536]	[524,578,562,745]	2	hSpCas9	negative selection	5564600
14117506	14117529	19	+	27260156	BXPC3	viability	CTCCTGCTCGCTGCCCTTCTTGG	PRKACA	ENSG00000072062	0.4342727718475692	[1263]	[1799,1743,1624,1983]	8	hSpCas9	negative selection	5628856
14106759	14106782	19	-	27260156	BXPC3	viability	GAAGATCCTCGACAAACAGAAGG	PRKACA	ENSG00000072062	0.10799806296905101	[279]	[292,261,329,389]	2	hSpCas9	negative selection	5628857
14106858	14106881	19	+	27260156	BXPC3	viability	TTCGTTCAAACTGATCCAAGTGG	PRKACA	ENSG00000072062	-0.024048432509278794	[578]	[589,454,624,733]	0	hSpCas9	negative selection	5628858
14117520	14117543	19	-	27260156	A673	viability	CAACGCCGCCGCCGCCAAGAAGG	PRKACA	ENSG00000072062	0.2742271998721677	[123]	[171,139,191,217]	6	hSpCas9	negative selection	5685849
14106845	14106868	19	-	27260156	A673	viability	TTTGAACGAATCAAGACCCTCGG	PRKACA	ENSG00000072062	0.07287202484273213	[451]	[562,468,621,632]	1	hSpCas9	negative selection	5685850
14106778	14106801	19	+	27260156	A673	viability	CTTCATGGCATAGTGGTTCCCGG	PRKACA	ENSG00000072062	0.05890160446365017	[536]	[766,547,714,668]	1	hSpCas9	negative selection	5685851
14117506	14117529	19	+	27260156	A673	viability	CTCCTGCTCGCTGCCCTTCTTGG	PRKACA	ENSG00000072062	0.49175982823503817	[1263]	[2108,1916,2313,2196]	9	hSpCas9	negative selection	5750107
14106759	14106782	19	-	27260156	A673	viability	GAAGATCCTCGACAAACAGAAGG	PRKACA	ENSG00000072062	0.16099094478843468	[279]	[450,304,341,417]	4	hSpCas9	negative selection	5750108
14106858	14106881	19	+	27260156	A673	viability	TTCGTTCAAACTGATCCAAGTGG	PRKACA	ENSG00000072062	-0.1134125980097275	[578]	[758,543,557,729]	-3	hSpCas9	negative selection	5750109
14117520	14117543	19	-	27260156	A375	viability	CAACGCCGCCGCCGCCAAGAAGG	PRKACA	ENSG00000072062	-0.5964324369556471	[123]	[57,187,68,81]	-7	hSpCas9	negative selection	5807100
14106845	14106868	19	-	27260156	A375	viability	TTTGAACGAATCAAGACCCTCGG	PRKACA	ENSG00000072062	-0.4768758220409893	[451]	[240,381,399,479]	-6	hSpCas9	negative selection	5807101
14106778	14106801	19	+	27260156	A375	viability	CTTCATGGCATAGTGGTTCCCGG	PRKACA	ENSG00000072062	-0.08733897333151289	[536]	[688,699,523,475]	-1	hSpCas9	negative selection	5807102
14117506	14117529	19	+	27260156	A375	viability	CTCCTGCTCGCTGCCCTTCTTGG	PRKACA	ENSG00000072062	0.729625345620746	[1263]	[2260,2996,2366,2255]	9	hSpCas9	negative selection	5871358
14106759	14106782	19	-	27260156	A375	viability	GAAGATCCTCGACAAACAGAAGG	PRKACA	ENSG00000072062	0.31199854036467567	[279]	[539,327,342,401]	4	hSpCas9	negative selection	5871359
14106858	14106881	19	+	27260156	A375	viability	TTCGTTCAAACTGATCCAAGTGG	PRKACA	ENSG00000072062	-0.432289363657317	[578]	[437,540,704,342]	-5	hSpCas9	negative selection	5871360
14117520	14117543	19	-	27260156	COLO741	viability	CAACGCCGCCGCCGCCAAGAAGG	PRKACA	ENSG00000072062	-0.4646772917911275	[123]	[86,127,125]	-7	hSpCas9	negative selection	5928351
14106845	14106868	19	-	27260156	COLO741	viability	TTTGAACGAATCAAGACCCTCGG	PRKACA	ENSG00000072062	-0.5469943706979216	[451]	[347,450,382]	-8	hSpCas9	negative selection	5928352
14106778	14106801	19	+	27260156	COLO741	viability	CTTCATGGCATAGTGGTTCCCGG	PRKACA	ENSG00000072062	-0.2678066137539228	[536]	[636,521,555]	-5	hSpCas9	negative selection	5928353
14117506	14117529	19	+	27260156	COLO741	viability	CTCCTGCTCGCTGCCCTTCTTGG	PRKACA	ENSG00000072062	0.2533873482263884	[1263]	[2121,1777,1889]	5	hSpCas9	negative selection	5992609
14106759	14106782	19	-	27260156	COLO741	viability	GAAGATCCTCGACAAACAGAAGG	PRKACA	ENSG00000072062	-0.17265789941398835	[279]	[366,220,363]	-4	hSpCas9	negative selection	5992610
14106858	14106881	19	+	27260156	COLO741	viability	TTCGTTCAAACTGATCCAAGTGG	PRKACA	ENSG00000072062	-0.28503771048695054	[578]	[642,515,659]	-6	hSpCas9	negative selection	5992611
14117520	14117543	19	-	27260156	CAL120	viability	CAACGCCGCCGCCGCCAAGAAGG	PRKACA	ENSG00000072062	0.5727633963219365	[123]	[138,316,218]	8	hSpCas9	negative selection	6049602
14106845	14106868	19	-	27260156	CAL120	viability	TTTGAACGAATCAAGACCCTCGG	PRKACA	ENSG00000072062	-0.25613910364146064	[451]	[470,654,289]	-4	hSpCas9	negative selection	6049603
14106778	14106801	19	+	27260156	CAL120	viability	CTTCATGGCATAGTGGTTCCCGG	PRKACA	ENSG00000072062	0.12285529859584304	[536]	[871,474,854]	1	hSpCas9	negative selection	6049604
14117506	14117529	19	+	27260156	CAL120	viability	CTCCTGCTCGCTGCCCTTCTTGG	PRKACA	ENSG00000072062	0.5713922632314752	[1263]	[2616,2046,2387]	8	hSpCas9	negative selection	6113860
14106759	14106782	19	-	27260156	CAL120	viability	GAAGATCCTCGACAAACAGAAGG	PRKACA	ENSG00000072062	0.4310373271669404	[279]	[933,191,354]	6	hSpCas9	negative selection	6113861
14106858	14106881	19	+	27260156	CAL120	viability	TTCGTTCAAACTGATCCAAGTGG	PRKACA	ENSG00000072062	0.3797791192106299	[578]	[732,1039,1006]	6	hSpCas9	negative selection	6113862
14117520	14117543	19	-	27260156	CADOES1	viability	CAACGCCGCCGCCGCCAAGAAGG	PRKACA	ENSG00000072062	0.40615064190592265	[123]	[187,178,174,65]	6	hSpCas9	negative selection	6170853
14106845	14106868	19	-	27260156	CADOES1	viability	TTTGAACGAATCAAGACCCTCGG	PRKACA	ENSG00000072062	-0.21782449708768312	[451]	[255,304,319,572]	-4	hSpCas9	negative selection	6170854
14106778	14106801	19	+	27260156	CADOES1	viability	CTTCATGGCATAGTGGTTCCCGG	PRKACA	ENSG00000072062	0.33831553100787126	[536]	[759,519,439,811]	5	hSpCas9	negative selection	6170855
14117506	14117529	19	+	27260156	CADOES1	viability	CTCCTGCTCGCTGCCCTTCTTGG	PRKACA	ENSG00000072062	0.6156738486979167	[1263]	[1874,1822,1710,1795]	8	hSpCas9	negative selection	6235111
14106759	14106782	19	-	27260156	CADOES1	viability	GAAGATCCTCGACAAACAGAAGG	PRKACA	ENSG00000072062	0.25139966365522354	[279]	[259,302,393,281]	4	hSpCas9	negative selection	6235112
14106858	14106881	19	+	27260156	CADOES1	viability	TTCGTTCAAACTGATCCAAGTGG	PRKACA	ENSG00000072062	0.11084227574490924	[578]	[705,364,627,627]	2	hSpCas9	negative selection	6235113
14117520	14117543	19	-	27260156	EWS502	viability	CAACGCCGCCGCCGCCAAGAAGG	PRKACA	ENSG00000072062	0.5316380611324039	[123]	[176,245,181,149]	8	hSpCas9	negative selection	6292104
14106845	14106868	19	-	27260156	EWS502	viability	TTTGAACGAATCAAGACCCTCGG	PRKACA	ENSG00000072062	-0.0534517227815895	[451]	[610,357,409,448]	-1	hSpCas9	negative selection	6292105
14106778	14106801	19	+	27260156	EWS502	viability	CTTCATGGCATAGTGGTTCCCGG	PRKACA	ENSG00000072062	0.3603963388533171	[536]	[699,546,812,880]	6	hSpCas9	negative selection	6292106
14117506	14117529	19	+	27260156	EWS502	viability	CTCCTGCTCGCTGCCCTTCTTGG	PRKACA	ENSG00000072062	0.6919574806283018	[1263]	[2173,2056,1963,2469]	9	hSpCas9	negative selection	6356362
14106759	14106782	19	-	27260156	EWS502	viability	GAAGATCCTCGACAAACAGAAGG	PRKACA	ENSG00000072062	-0.0007169720532717028	[279]	[244,233,371,346]	0	hSpCas9	negative selection	6356363
14106858	14106881	19	+	27260156	EWS502	viability	TTCGTTCAAACTGATCCAAGTGG	PRKACA	ENSG00000072062	0.47931489483200584	[578]	[879,722,805,1020]	8	hSpCas9	negative selection	6356364
14117520	14117543	19	-	27260156	EW8	viability	CAACGCCGCCGCCGCCAAGAAGG	PRKACA	ENSG00000072062	0.118213103571438	[123]	[106,119,125,79]	2	hSpCas9	negative selection	6413355
14106845	14106868	19	-	27260156	EW8	viability	TTTGAACGAATCAAGACCCTCGG	PRKACA	ENSG00000072062	-0.21837709605269998	[451]	[475,293,185,341]	-4	hSpCas9	negative selection	6413356
14106778	14106801	19	+	27260156	EW8	viability	CTTCATGGCATAGTGGTTCCCGG	PRKACA	ENSG00000072062	0.24514307980342503	[536]	[656,569,443,418]	4	hSpCas9	negative selection	6413357
14117506	14117529	19	+	27260156	EW8	viability	CTCCTGCTCGCTGCCCTTCTTGG	PRKACA	ENSG00000072062	0.45228564908202595	[1263]	[1575,1462,1354,1235]	7	hSpCas9	negative selection	6477613
14106759	14106782	19	-	27260156	EW8	viability	GAAGATCCTCGACAAACAGAAGG	PRKACA	ENSG00000072062	0.15157199886170192	[279]	[359,250,225,186]	3	hSpCas9	negative selection	6477614
14106858	14106881	19	+	27260156	EW8	viability	TTCGTTCAAACTGATCCAAGTGG	PRKACA	ENSG00000072062	-0.10834731579589782	[578]	[501,486,349,422]	-2	hSpCas9	negative selection	6477615
14117520	14117543	19	-	27260156	CORL105	viability	CAACGCCGCCGCCGCCAAGAAGG	PRKACA	ENSG00000072062	0.24215358265831144	[123]	[110,214,285,89]	4	hSpCas9	negative selection	6534606
14106845	14106868	19	-	27260156	CORL105	viability	TTTGAACGAATCAAGACCCTCGG	PRKACA	ENSG00000072062	-0.20017491258077977	[451]	[385,336,633,511]	-4	hSpCas9	negative selection	6534607
14106778	14106801	19	+	27260156	CORL105	viability	CTTCATGGCATAGTGGTTCCCGG	PRKACA	ENSG00000072062	0.245429730520196	[536]	[740,734,840,678]	4	hSpCas9	negative selection	6534608
14117506	14117529	19	+	27260156	CORL105	viability	CTCCTGCTCGCTGCCCTTCTTGG	PRKACA	ENSG00000072062	0.3894793593779444	[1263]	[2134,1647,1964,2020]	7	hSpCas9	negative selection	6598864
14106759	14106782	19	-	27260156	CORL105	viability	GAAGATCCTCGACAAACAGAAGG	PRKACA	ENSG00000072062	-0.22522912966505493	[279]	[255,242,297,326]	-4	hSpCas9	negative selection	6598865
14106858	14106881	19	+	27260156	CORL105	viability	TTCGTTCAAACTGATCCAAGTGG	PRKACA	ENSG00000072062	-0.318666357624583	[578]	[579,377,638,595]	-5	hSpCas9	negative selection	6598866
14117520	14117543	19	-	27260156	HS294T	viability	CAACGCCGCCGCCGCCAAGAAGG	PRKACA	ENSG00000072062	-0.07145967169190914	[123]	[27,39,56,61]	-1	hSpCas9	negative selection	6655857
14106845	14106868	19	-	27260156	HS294T	viability	TTTGAACGAATCAAGACCCTCGG	PRKACA	ENSG00000072062	0.07952567676439579	[451]	[170,129,136,326]	1	hSpCas9	negative selection	6655858
14106778	14106801	19	+	27260156	HS294T	viability	CTTCATGGCATAGTGGTTCCCGG	PRKACA	ENSG00000072062	0.3024891535561934	[536]	[238,218,213,373]	4	hSpCas9	negative selection	6655859
14117506	14117529	19	+	27260156	HS294T	viability	CTCCTGCTCGCTGCCCTTCTTGG	PRKACA	ENSG00000072062	0.299437682216235	[1263]	[593,493,639,695]	4	hSpCas9	negative selection	6720115
14106759	14106782	19	-	27260156	HS294T	viability	GAAGATCCTCGACAAACAGAAGG	PRKACA	ENSG00000072062	0.20536048497714643	[279]	[76,121,182,120]	2	hSpCas9	negative selection	6720116
14106858	14106881	19	+	27260156	HS294T	viability	TTCGTTCAAACTGATCCAAGTGG	PRKACA	ENSG00000072062	-0.0680647166665228	[578]	[160,228,254,212]	-1	hSpCas9	negative selection	6720117
14117520	14117543	19	-	27260156	HCC44	viability	CAACGCCGCCGCCGCCAAGAAGG	PRKACA	ENSG00000072062	0.7345478847714026	[123]	[261,143,481,105]	9	hSpCas9	negative selection	6777108
14106845	14106868	19	-	27260156	HCC44	viability	TTTGAACGAATCAAGACCCTCGG	PRKACA	ENSG00000072062	-0.08063184948825111	[451]	[712,420,592,258]	-1	hSpCas9	negative selection	6777109
14106778	14106801	19	+	27260156	HCC44	viability	CTTCATGGCATAGTGGTTCCCGG	PRKACA	ENSG00000072062	0.45688475917056104	[536]	[598,609,1434,798]	7	hSpCas9	negative selection	6777110
14117506	14117529	19	+	27260156	HCC44	viability	CTCCTGCTCGCTGCCCTTCTTGG	PRKACA	ENSG00000072062	0.5570736715277731	[1263]	[1963,2319,2064,1999]	8	hSpCas9	negative selection	6841366
14106759	14106782	19	-	27260156	HCC44	viability	GAAGATCCTCGACAAACAGAAGG	PRKACA	ENSG00000072062	0.1930374248369654	[279]	[512,405,292,232]	3	hSpCas9	negative selection	6841367
14106858	14106881	19	+	27260156	HCC44	viability	TTCGTTCAAACTGATCCAAGTGG	PRKACA	ENSG00000072062	0.2037858139667328	[578]	[694,650,846,839]	3	hSpCas9	negative selection	6841368
14117520	14117543	19	-	27260156	G402	viability	CAACGCCGCCGCCGCCAAGAAGG	PRKACA	ENSG00000072062	-0.5753174011565927	[123]	[64,119,144,72]	-6	hSpCas9	negative selection	6898359
14106845	14106868	19	-	27260156	G402	viability	TTTGAACGAATCAAGACCCTCGG	PRKACA	ENSG00000072062	-0.30499890896711024	[451]	[655,190,581,373]	-4	hSpCas9	negative selection	6898360
14106778	14106801	19	+	27260156	G402	viability	CTTCATGGCATAGTGGTTCCCGG	PRKACA	ENSG00000072062	0.632924792390913	[536]	[1446,1069,1253,385]	7	hSpCas9	negative selection	6898361
14117506	14117529	19	+	27260156	G402	viability	CTCCTGCTCGCTGCCCTTCTTGG	PRKACA	ENSG00000072062	0.7171463593242857	[1263]	[2665,2559,1789,3107]	8	hSpCas9	negative selection	6962617
14106759	14106782	19	-	27260156	G402	viability	GAAGATCCTCGACAAACAGAAGG	PRKACA	ENSG00000072062	-0.22569520137709143	[279]	[415,187,422,158]	-3	hSpCas9	negative selection	6962618
14106858	14106881	19	+	27260156	G402	viability	TTCGTTCAAACTGATCCAAGTGG	PRKACA	ENSG00000072062	-0.15393489481074277	[578]	[577,634,865,458]	-2	hSpCas9	negative selection	6962619
14117520	14117543	19	-	27260156	L33	viability	CAACGCCGCCGCCGCCAAGAAGG	PRKACA	ENSG00000072062	0.4650522223638107	[123]	[172,51,143,155]	8	hSpCas9	negative selection	7019610
14106845	14106868	19	-	27260156	L33	viability	TTTGAACGAATCAAGACCCTCGG	PRKACA	ENSG00000072062	0.42986069662955784	[451]	[481,266,438,606]	8	hSpCas9	negative selection	7019611
14106778	14106801	19	+	27260156	L33	viability	CTTCATGGCATAGTGGTTCCCGG	PRKACA	ENSG00000072062	0.19297543440010234	[536]	[491,228,453,684]	4	hSpCas9	negative selection	7019612
14117506	14117529	19	+	27260156	L33	viability	CTCCTGCTCGCTGCCCTTCTTGG	PRKACA	ENSG00000072062	0.3343541481117893	[1263]	[1657,627,973,1631]	7	hSpCas9	negative selection	7083868
14106759	14106782	19	-	27260156	L33	viability	GAAGATCCTCGACAAACAGAAGG	PRKACA	ENSG00000072062	0.025984430751227583	[279]	[315,117,143,305]	0	hSpCas9	negative selection	7083869
14106858	14106881	19	+	27260156	L33	viability	TTCGTTCAAACTGATCCAAGTGG	PRKACA	ENSG00000072062	0.04308705904233329	[578]	[596,213,389,645]	1	hSpCas9	negative selection	7083870
14117520	14117543	19	-	27260156	K562	viability	CAACGCCGCCGCCGCCAAGAAGG	PRKACA	ENSG00000072062	0.1822161578482362	[123]	[169,260,12,71]	2	hSpCas9	negative selection	7140861
14106845	14106868	19	-	27260156	K562	viability	TTTGAACGAATCAAGACCCTCGG	PRKACA	ENSG00000072062	-0.3783855057630176	[451]	[344,332,351,217]	-4	hSpCas9	negative selection	7140862
14106778	14106801	19	+	27260156	K562	viability	CTTCATGGCATAGTGGTTCCCGG	PRKACA	ENSG00000072062	0.6395390715151036	[536]	[406,535,496,1408]	7	hSpCas9	negative selection	7140863
14117506	14117529	19	+	27260156	K562	viability	CTCCTGCTCGCTGCCCTTCTTGG	PRKACA	ENSG00000072062	0.6384032338466354	[1263]	[1632,2412,1695,1311]	7	hSpCas9	negative selection	7205119
14106759	14106782	19	-	27260156	K562	viability	GAAGATCCTCGACAAACAGAAGG	PRKACA	ENSG00000072062	0.6533407137372522	[279]	[427,480,369,300]	8	hSpCas9	negative selection	7205120
14106858	14106881	19	+	27260156	K562	viability	TTCGTTCAAACTGATCCAAGTGG	PRKACA	ENSG00000072062	-0.028123404013157716	[578]	[657,593,323,459]	0	hSpCas9	negative selection	7205121
14117520	14117543	19	-	27260156	HT29	viability	CAACGCCGCCGCCGCCAAGAAGG	PRKACA	ENSG00000072062	-0.40412616372490695	[123]	[132,98,144,81]	-6	hSpCas9	negative selection	7262112
14106845	14106868	19	-	27260156	HT29	viability	TTTGAACGAATCAAGACCCTCGG	PRKACA	ENSG00000072062	0.015732403034084956	[451]	[666,525,565,474]	0	hSpCas9	negative selection	7262113
14106778	14106801	19	+	27260156	HT29	viability	CTTCATGGCATAGTGGTTCCCGG	PRKACA	ENSG00000072062	0.04993317351802101	[536]	[636,767,782,532]	0	hSpCas9	negative selection	7262114
14117506	14117529	19	+	27260156	HT29	viability	CTCCTGCTCGCTGCCCTTCTTGG	PRKACA	ENSG00000072062	0.30607778605577485	[1263]	[2130,1977,1821,1702]	6	hSpCas9	negative selection	7326370
14106759	14106782	19	-	27260156	HT29	viability	GAAGATCCTCGACAAACAGAAGG	PRKACA	ENSG00000072062	0.2879167480931852	[279]	[299,509,518,338]	5	hSpCas9	negative selection	7326371
14106858	14106881	19	+	27260156	HT29	viability	TTCGTTCAAACTGATCCAAGTGG	PRKACA	ENSG00000072062	0.18754947026227214	[578]	[1032,547,935,692]	3	hSpCas9	negative selection	7326372
14117520	14117543	19	-	27260156	MHHES1	viability	CAACGCCGCCGCCGCCAAGAAGG	PRKACA	ENSG00000072062	0.1617152727922868	[123]	[180,104,256,91]	3	hSpCas9	negative selection	7383363
14106845	14106868	19	-	27260156	MHHES1	viability	TTTGAACGAATCAAGACCCTCGG	PRKACA	ENSG00000072062	-0.13942254387722386	[451]	[550,585,397,351]	-3	hSpCas9	negative selection	7383364
14106778	14106801	19	+	27260156	MHHES1	viability	CTTCATGGCATAGTGGTTCCCGG	PRKACA	ENSG00000072062	0.1605472575659148	[536]	[833,650,750,508]	3	hSpCas9	negative selection	7383365
14117506	14117529	19	+	27260156	MHHES1	viability	CTCCTGCTCGCTGCCCTTCTTGG	PRKACA	ENSG00000072062	0.6490869936311825	[1263]	[2335,2587,2256,1838]	9	hSpCas9	negative selection	7447621
14106759	14106782	19	-	27260156	MHHES1	viability	GAAGATCCTCGACAAACAGAAGG	PRKACA	ENSG00000072062	0.10600325310146452	[279]	[333,363,195,433]	2	hSpCas9	negative selection	7447622
14106858	14106881	19	+	27260156	MHHES1	viability	TTCGTTCAAACTGATCCAAGTGG	PRKACA	ENSG00000072062	-0.20828825081768587	[578]	[645,650,561,434]	-4	hSpCas9	negative selection	7447623
14117520	14117543	19	-	27260156	MEWO	viability	CAACGCCGCCGCCGCCAAGAAGG	PRKACA	ENSG00000072062	0.18603189942697806	[123]	[167,106,127]	4	hSpCas9	negative selection	7504614
14106845	14106868	19	-	27260156	MEWO	viability	TTTGAACGAATCAAGACCCTCGG	PRKACA	ENSG00000072062	-0.2316170399479804	[451]	[443,282,369]	-5	hSpCas9	negative selection	7504615
14106778	14106801	19	+	27260156	MEWO	viability	CTTCATGGCATAGTGGTTCCCGG	PRKACA	ENSG00000072062	0.08100847362694669	[536]	[520,552,517]	1	hSpCas9	negative selection	7504616
14117506	14117529	19	+	27260156	MEWO	viability	CTCCTGCTCGCTGCCCTTCTTGG	PRKACA	ENSG00000072062	0.36071726253262026	[1263]	[1826,1486,1300]	7	hSpCas9	negative selection	7568872
14106759	14106782	19	-	27260156	MEWO	viability	GAAGATCCTCGACAAACAGAAGG	PRKACA	ENSG00000072062	0.1110703365785185	[279]	[345,266,247]	2	hSpCas9	negative selection	7568873
14106858	14106881	19	+	27260156	MEWO	viability	TTCGTTCAAACTGATCCAAGTGG	PRKACA	ENSG00000072062	0.11326289963929487	[578]	[654,594,520]	2	hSpCas9	negative selection	7568874
14117520	14117543	19	-	27260156	LNCAPCLONEFGC	viability	CAACGCCGCCGCCGCCAAGAAGG	PRKACA	ENSG00000072062	-0.24729988131428482	[123]	[77,87,173,50]	-4	hSpCas9	negative selection	7625865
14106845	14106868	19	-	27260156	LNCAPCLONEFGC	viability	TTTGAACGAATCAAGACCCTCGG	PRKACA	ENSG00000072062	-0.6469312916814577	[451]	[260,240,300,249]	-7	hSpCas9	negative selection	7625866
14106778	14106801	19	+	27260156	LNCAPCLONEFGC	viability	CTTCATGGCATAGTGGTTCCCGG	PRKACA	ENSG00000072062	0.12933788085003817	[536]	[403,545,575,609]	2	hSpCas9	negative selection	7625867
14117506	14117529	19	+	27260156	LNCAPCLONEFGC	viability	CTCCTGCTCGCTGCCCTTCTTGG	PRKACA	ENSG00000072062	0.5469980732361914	[1263]	[1804,1582,1781,1539]	8	hSpCas9	negative selection	7690123
14106759	14106782	19	-	27260156	LNCAPCLONEFGC	viability	GAAGATCCTCGACAAACAGAAGG	PRKACA	ENSG00000072062	0.05856734906880079	[279]	[209,232,327,297]	0	hSpCas9	negative selection	7690124
14106858	14106881	19	+	27260156	LNCAPCLONEFGC	viability	TTCGTTCAAACTGATCCAAGTGG	PRKACA	ENSG00000072062	0.14565500218092198	[578]	[560,610,574,570]	2	hSpCas9	negative selection	7690125
14117520	14117543	19	-	27260156	PANC0327	viability	CAACGCCGCCGCCGCCAAGAAGG	PRKACA	ENSG00000072062	0.2893017913760718	[123]	[122,136,79,196]	4	hSpCas9	negative selection	7747116
14106845	14106868	19	-	27260156	PANC0327	viability	TTTGAACGAATCAAGACCCTCGG	PRKACA	ENSG00000072062	-0.6944304953581969	[451]	[300,221,198,277]	-7	hSpCas9	negative selection	7747117
14106778	14106801	19	+	27260156	PANC0327	viability	CTTCATGGCATAGTGGTTCCCGG	PRKACA	ENSG00000072062	0.2858776999493866	[536]	[833,219,865,473]	4	hSpCas9	negative selection	7747118
14117506	14117529	19	+	27260156	PANC0327	viability	CTCCTGCTCGCTGCCCTTCTTGG	PRKACA	ENSG00000072062	0.24189339788884867	[1263]	[1498,1131,1322,1395]	3	hSpCas9	negative selection	7811374
14106759	14106782	19	-	27260156	PANC0327	viability	GAAGATCCTCGACAAACAGAAGG	PRKACA	ENSG00000072062	-0.1953426170739918	[279]	[187,259,239,172]	-3	hSpCas9	negative selection	7811375
14106858	14106881	19	+	27260156	PANC0327	viability	TTCGTTCAAACTGATCCAAGTGG	PRKACA	ENSG00000072062	0.1729794017541843	[578]	[458,405,771,694]	2	hSpCas9	negative selection	7811376
14117520	14117543	19	-	27260156	NCIH2009	viability	CAACGCCGCCGCCGCCAAGAAGG	PRKACA	ENSG00000072062	0.06312260956607485	[123]	[238,188,125]	0	hSpCas9	negative selection	7868367
14106845	14106868	19	-	27260156	NCIH2009	viability	TTTGAACGAATCAAGACCCTCGG	PRKACA	ENSG00000072062	-0.2788911984479005	[451]	[555,611,397]	-4	hSpCas9	negative selection	7868368
14106778	14106801	19	+	27260156	NCIH2009	viability	CTTCATGGCATAGTGGTTCCCGG	PRKACA	ENSG00000072062	0.3350913151550601	[536]	[1032,770,1053]	4	hSpCas9	negative selection	7868369
14117506	14117529	19	+	27260156	NCIH2009	viability	CTCCTGCTCGCTGCCCTTCTTGG	PRKACA	ENSG00000072062	0.6372442398826752	[1263]	[3550,2228,2623]	8	hSpCas9	negative selection	7932625
14106759	14106782	19	-	27260156	NCIH2009	viability	GAAGATCCTCGACAAACAGAAGG	PRKACA	ENSG00000072062	0.0358365791586277	[279]	[455,307,450]	0	hSpCas9	negative selection	7932626
14106858	14106881	19	+	27260156	NCIH2009	viability	TTCGTTCAAACTGATCCAAGTGG	PRKACA	ENSG00000072062	0.4461143556235687	[578]	[1498,1038,845]	6	hSpCas9	negative selection	7932627
14117520	14117543	19	-	27260156	NCIH1373	viability	CAACGCCGCCGCCGCCAAGAAGG	PRKACA	ENSG00000072062	0.2138146958942737	[123]	[161,144,55,76]	2	hSpCas9	negative selection	7989618
14106845	14106868	19	-	27260156	NCIH1373	viability	TTTGAACGAATCAAGACCCTCGG	PRKACA	ENSG00000072062	-0.0188841714942466	[451]	[932,303,213,170]	0	hSpCas9	negative selection	7989619
14106778	14106801	19	+	27260156	NCIH1373	viability	CTTCATGGCATAGTGGTTCCCGG	PRKACA	ENSG00000072062	0.11324513243618312	[536]	[968,589,580,133]	1	hSpCas9	negative selection	7989620
14117506	14117529	19	+	27260156	NCIH1373	viability	CTCCTGCTCGCTGCCCTTCTTGG	PRKACA	ENSG00000072062	0.7267895704129705	[1263]	[2489,2527,1939,636]	7	hSpCas9	negative selection	8053876
14106759	14106782	19	-	27260156	NCIH1373	viability	GAAGATCCTCGACAAACAGAAGG	PRKACA	ENSG00000072062	-0.16424615229615702	[279]	[221,212,404,71]	-2	hSpCas9	negative selection	8053877
14106858	14106881	19	+	27260156	NCIH1373	viability	TTCGTTCAAACTGATCCAAGTGG	PRKACA	ENSG00000072062	0.36998869973007253	[578]	[1029,1096,578,167]	3	hSpCas9	negative selection	8053878
14117520	14117543	19	-	27260156	PATU8902	viability	CAACGCCGCCGCCGCCAAGAAGG	PRKACA	ENSG00000072062	-0.34694150268040747	[123]	[175,215,10,175]	-3	hSpCas9	negative selection	8110869
14106845	14106868	19	-	27260156	PATU8902	viability	TTTGAACGAATCAAGACCCTCGG	PRKACA	ENSG00000072062	-1.816280470803682	[451]	[219,184,88,250]	-8	hSpCas9	negative selection	8110870
14106778	14106801	19	+	27260156	PATU8902	viability	CTTCATGGCATAGTGGTTCCCGG	PRKACA	ENSG00000072062	-0.5381005427842845	[536]	[558,585,420,513]	-5	hSpCas9	negative selection	8110871
14117506	14117529	19	+	27260156	PATU8902	viability	CTCCTGCTCGCTGCCCTTCTTGG	PRKACA	ENSG00000072062	0.6408493644735438	[1263]	[2551,2525,3336,2341]	6	hSpCas9	negative selection	8175127
14106759	14106782	19	-	27260156	PATU8902	viability	GAAGATCCTCGACAAACAGAAGG	PRKACA	ENSG00000072062	-0.7474914939342557	[279]	[88,53,561,124]	-6	hSpCas9	negative selection	8175128
14106858	14106881	19	+	27260156	PATU8902	viability	TTCGTTCAAACTGATCCAAGTGG	PRKACA	ENSG00000072062	-0.45330894590498205	[578]	[383,420,522,1103]	-4	hSpCas9	negative selection	8175129
14117520	14117543	19	-	27260156	PANC1	viability	CAACGCCGCCGCCGCCAAGAAGG	PRKACA	ENSG00000072062	-0.38614022022144856	[123]	[101,33,86,89]	-6	hSpCas9	negative selection	8232120
14106845	14106868	19	-	27260156	PANC1	viability	TTTGAACGAATCAAGACCCTCGG	PRKACA	ENSG00000072062	-0.5584975146169493	[451]	[227,349,211,275]	-7	hSpCas9	negative selection	8232121
14106778	14106801	19	+	27260156	PANC1	viability	CTTCATGGCATAGTGGTTCCCGG	PRKACA	ENSG00000072062	0.20507706650694207	[536]	[483,505,677,458]	3	hSpCas9	negative selection	8232122
14117506	14117529	19	+	27260156	PANC1	viability	CTCCTGCTCGCTGCCCTTCTTGG	PRKACA	ENSG00000072062	0.614324076133524	[1263]	[1509,2086,1814,1351]	8	hSpCas9	negative selection	8296378
14106759	14106782	19	-	27260156	PANC1	viability	GAAGATCCTCGACAAACAGAAGG	PRKACA	ENSG00000072062	-0.11082064750461995	[279]	[129,214,271,263]	-2	hSpCas9	negative selection	8296379
14106858	14106881	19	+	27260156	PANC1	viability	TTCGTTCAAACTGATCCAAGTGG	PRKACA	ENSG00000072062	-0.036185141955018485	[578]	[646,755,418,207]	0	hSpCas9	negative selection	8296380
14117520	14117543	19	-	27260156	PANC0813	viability	CAACGCCGCCGCCGCCAAGAAGG	PRKACA	ENSG00000072062	0.27801509025499094	[123]	[87,121,197,283]	4	hSpCas9	negative selection	8353371
14106845	14106868	19	-	27260156	PANC0813	viability	TTTGAACGAATCAAGACCCTCGG	PRKACA	ENSG00000072062	-0.11564353027918933	[451]	[514,366,637,444]	-2	hSpCas9	negative selection	8353372
14106778	14106801	19	+	27260156	PANC0813	viability	CTTCATGGCATAGTGGTTCCCGG	PRKACA	ENSG00000072062	0.024855248766132265	[536]	[684,602,692,591]	0	hSpCas9	negative selection	8353373
14117506	14117529	19	+	27260156	PANC0813	viability	CTCCTGCTCGCTGCCCTTCTTGG	PRKACA	ENSG00000072062	0.4010887744347895	[1263]	[2214,2034,1664,1946]	6	hSpCas9	negative selection	8417629
14106759	14106782	19	-	27260156	PANC0813	viability	GAAGATCCTCGACAAACAGAAGG	PRKACA	ENSG00000072062	-0.4660019516731667	[279]	[188,272,323,165]	-6	hSpCas9	negative selection	8417630
14106858	14106881	19	+	27260156	PANC0813	viability	TTCGTTCAAACTGATCCAAGTGG	PRKACA	ENSG00000072062	-0.3937635775256076	[578]	[626,357,623,473]	-6	hSpCas9	negative selection	8417631
14117520	14117543	19	-	27260156	RDES	viability	CAACGCCGCCGCCGCCAAGAAGG	PRKACA	ENSG00000072062	0.3075800296048703	[123]	[88,248,184,192]	5	hSpCas9	negative selection	8474622
14106845	14106868	19	-	27260156	RDES	viability	TTTGAACGAATCAAGACCCTCGG	PRKACA	ENSG00000072062	-0.1898970867839664	[451]	[326,362,628,548]	-3	hSpCas9	negative selection	8474623
14106778	14106801	19	+	27260156	RDES	viability	CTTCATGGCATAGTGGTTCCCGG	PRKACA	ENSG00000072062	0.10388362901834658	[536]	[588,561,682,855]	1	hSpCas9	negative selection	8474624
14117506	14117529	19	+	27260156	RDES	viability	CTCCTGCTCGCTGCCCTTCTTGG	PRKACA	ENSG00000072062	0.7957311282518502	[1263]	[1973,2538,2559,3160]	9	hSpCas9	negative selection	8538880
14106759	14106782	19	-	27260156	RDES	viability	GAAGATCCTCGACAAACAGAAGG	PRKACA	ENSG00000072062	0.07201208415018545	[279]	[223,385,378,383]	1	hSpCas9	negative selection	8538881
14106858	14106881	19	+	27260156	RDES	viability	TTCGTTCAAACTGATCCAAGTGG	PRKACA	ENSG00000072062	-0.1432838667052029	[578]	[514,581,717,602]	-2	hSpCas9	negative selection	8538882
14117520	14117543	19	-	27260156	PC3	viability	CAACGCCGCCGCCGCCAAGAAGG	PRKACA	ENSG00000072062	0.5245497390585285	[123]	[67,275,264,165]	9	hSpCas9	negative selection	8595873
14106845	14106868	19	-	27260156	PC3	viability	TTTGAACGAATCAAGACCCTCGG	PRKACA	ENSG00000072062	-0.02119215861953467	[451]	[274,422,762,472]	0	hSpCas9	negative selection	8595874
14106778	14106801	19	+	27260156	PC3	viability	CTTCATGGCATAGTGGTTCCCGG	PRKACA	ENSG00000072062	0.03613802882008052	[536]	[365,513,882,589]	0	hSpCas9	negative selection	8595875
14117506	14117529	19	+	27260156	PC3	viability	CTCCTGCTCGCTGCCCTTCTTGG	PRKACA	ENSG00000072062	0.4745526985835762	[1263]	[1011,1986,2970,1652]	8	hSpCas9	negative selection	8660131
14106759	14106782	19	-	27260156	PC3	viability	GAAGATCCTCGACAAACAGAAGG	PRKACA	ENSG00000072062	9.997632291858238e-05	[279]	[255,123,619,228]	0	hSpCas9	negative selection	8660132
14106858	14106881	19	+	27260156	PC3	viability	TTCGTTCAAACTGATCCAAGTGG	PRKACA	ENSG00000072062	-0.2489088730351974	[578]	[367,327,731,621]	-5	hSpCas9	negative selection	8660133
14117520	14117543	19	-	27260156	PATU8988T	viability	CAACGCCGCCGCCGCCAAGAAGG	PRKACA	ENSG00000072062	0.6732679687103202	[123]	[118,300,172,180]	9	hSpCas9	negative selection	8717124
14106845	14106868	19	-	27260156	PATU8988T	viability	TTTGAACGAATCAAGACCCTCGG	PRKACA	ENSG00000072062	0.1991627549240703	[451]	[470,518,476,543]	3	hSpCas9	negative selection	8717125
14106778	14106801	19	+	27260156	PATU8988T	viability	CTTCATGGCATAGTGGTTCCCGG	PRKACA	ENSG00000072062	0.3830741233778383	[536]	[646,639,820,585]	6	hSpCas9	negative selection	8717126
14117506	14117529	19	+	27260156	PATU8988T	viability	CTCCTGCTCGCTGCCCTTCTTGG	PRKACA	ENSG00000072062	0.4908146202900783	[1263]	[1307,2090,1668,1842]	7	hSpCas9	negative selection	8781382
14106759	14106782	19	-	27260156	PATU8988T	viability	GAAGATCCTCGACAAACAGAAGG	PRKACA	ENSG00000072062	-0.00884995546424494	[279]	[212,442,131,308]	0	hSpCas9	negative selection	8781383
14106858	14106881	19	+	27260156	PATU8988T	viability	TTCGTTCAAACTGATCCAAGTGG	PRKACA	ENSG00000072062	0.16787099384160825	[578]	[917,602,387,603]	3	hSpCas9	negative selection	8781384
14117520	14117543	19	-	27260156	T47D	viability	CAACGCCGCCGCCGCCAAGAAGG	PRKACA	ENSG00000072062	0.3225520729707363	[123]	[186,212,167,150]	6	hSpCas9	negative selection	8838375
14106845	14106868	19	-	27260156	T47D	viability	TTTGAACGAATCAAGACCCTCGG	PRKACA	ENSG00000072062	-0.1297382605797163	[451]	[423,491,466,542]	-3	hSpCas9	negative selection	8838376
14106778	14106801	19	+	27260156	T47D	viability	CTTCATGGCATAGTGGTTCCCGG	PRKACA	ENSG00000072062	0.09924123444845051	[536]	[658,595,746,683]	2	hSpCas9	negative selection	8838377
14117506	14117529	19	+	27260156	T47D	viability	CTCCTGCTCGCTGCCCTTCTTGG	PRKACA	ENSG00000072062	0.48341287361690877	[1263]	[2009,1863,2227,2148]	8	hSpCas9	negative selection	8902633
14106759	14106782	19	-	27260156	T47D	viability	GAAGATCCTCGACAAACAGAAGG	PRKACA	ENSG00000072062	0.24721436485859682	[279]	[370,353,347,481]	5	hSpCas9	negative selection	8902634
14106858	14106881	19	+	27260156	T47D	viability	TTCGTTCAAACTGATCCAAGTGG	PRKACA	ENSG00000072062	0.09604797662800973	[578]	[801,601,779,708]	2	hSpCas9	negative selection	8902635
14117520	14117543	19	-	27260156	SU8686	viability	CAACGCCGCCGCCGCCAAGAAGG	PRKACA	ENSG00000072062	0.10089857732919394	[123]	[80,136,157,160]	1	hSpCas9	negative selection	8959626
14106845	14106868	19	-	27260156	SU8686	viability	TTTGAACGAATCAAGACCCTCGG	PRKACA	ENSG00000072062	-0.19748519251323307	[451]	[430,348,396,382]	-3	hSpCas9	negative selection	8959627
14106778	14106801	19	+	27260156	SU8686	viability	CTTCATGGCATAGTGGTTCCCGG	PRKACA	ENSG00000072062	0.18778580277898788	[536]	[594,512,653,686]	3	hSpCas9	negative selection	8959628
14117506	14117529	19	+	27260156	SU8686	viability	CTCCTGCTCGCTGCCCTTCTTGG	PRKACA	ENSG00000072062	0.5022636056843695	[1263]	[1430,1778,1784,2199]	8	hSpCas9	negative selection	9023884
14106759	14106782	19	-	27260156	SU8686	viability	GAAGATCCTCGACAAACAGAAGG	PRKACA	ENSG00000072062	-0.3776443794959915	[279]	[266,153,225,206]	-6	hSpCas9	negative selection	9023885
14106858	14106881	19	+	27260156	SU8686	viability	TTCGTTCAAACTGATCCAAGTGG	PRKACA	ENSG00000072062	-0.028873409754667068	[578]	[584,474,505,711]	0	hSpCas9	negative selection	9023886
14117520	14117543	19	-	27260156	SKES1	viability	CAACGCCGCCGCCGCCAAGAAGG	PRKACA	ENSG00000072062	-0.1888416241636881	[123]	[65,166,89,110]	-4	hSpCas9	negative selection	9080877
14106845	14106868	19	-	27260156	SKES1	viability	TTTGAACGAATCAAGACCCTCGG	PRKACA	ENSG00000072062	-0.1707856606740856	[451]	[344,560,378,332]	-4	hSpCas9	negative selection	9080878
14106778	14106801	19	+	27260156	SKES1	viability	CTTCATGGCATAGTGGTTCCCGG	PRKACA	ENSG00000072062	0.050436025847137356	[536]	[711,599,503,438]	1	hSpCas9	negative selection	9080879
14117506	14117529	19	+	27260156	SKES1	viability	CTCCTGCTCGCTGCCCTTCTTGG	PRKACA	ENSG00000072062	0.48031608064494913	[1263]	[1731,2051,1653,1627]	8	hSpCas9	negative selection	9145135
14106759	14106782	19	-	27260156	SKES1	viability	GAAGATCCTCGACAAACAGAAGG	PRKACA	ENSG00000072062	0.14557129137769353	[279]	[253,361,333,283]	3	hSpCas9	negative selection	9145136
14106858	14106881	19	+	27260156	SKES1	viability	TTCGTTCAAACTGATCCAAGTGG	PRKACA	ENSG00000072062	0.10075536164455212	[578]	[920,690,453,474]	2	hSpCas9	negative selection	9145137
14117520	14117543	19	-	27260156	TOV112D	viability	CAACGCCGCCGCCGCCAAGAAGG	PRKACA	ENSG00000072062	0.5644992143412022	[123]	[182,314,134,134]	8	hSpCas9	negative selection	9202128
14106845	14106868	19	-	27260156	TOV112D	viability	TTTGAACGAATCAAGACCCTCGG	PRKACA	ENSG00000072062	-0.14871208085073448	[451]	[409,772,252,289]	-3	hSpCas9	negative selection	9202129
14106778	14106801	19	+	27260156	TOV112D	viability	CTTCATGGCATAGTGGTTCCCGG	PRKACA	ENSG00000072062	-0.1549750573850749	[536]	[513,551,474,411]	-3	hSpCas9	negative selection	9202130
14117506	14117529	19	+	27260156	TOV112D	viability	CTCCTGCTCGCTGCCCTTCTTGG	PRKACA	ENSG00000072062	0.5812259280867773	[1263]	[1792,1825,2044,1883]	9	hSpCas9	negative selection	9266386
14106759	14106782	19	-	27260156	TOV112D	viability	GAAGATCCTCGACAAACAGAAGG	PRKACA	ENSG00000072062	-0.16615457822754143	[279]	[240,331,168,275]	-3	hSpCas9	negative selection	9266387
14106858	14106881	19	+	27260156	TOV112D	viability	TTCGTTCAAACTGATCCAAGTGG	PRKACA	ENSG00000072062	0.03178380232306832	[578]	[523,807,512,572]	0	hSpCas9	negative selection	9266388
14117520	14117543	19	-	27260156	TC71	viability	CAACGCCGCCGCCGCCAAGAAGG	PRKACA	ENSG00000072062	0.3063023907224187	[123]	[209,148,147,148]	7	hSpCas9	negative selection	9323379
14106845	14106868	19	-	27260156	TC71	viability	TTTGAACGAATCAAGACCCTCGG	PRKACA	ENSG00000072062	0.06603937552622212	[451]	[429,559,439,608]	1	hSpCas9	negative selection	9323380
14106778	14106801	19	+	27260156	TC71	viability	CTTCATGGCATAGTGGTTCCCGG	PRKACA	ENSG00000072062	0.10751191388458342	[536]	[605,677,620,572]	2	hSpCas9	negative selection	9323381
14117506	14117529	19	+	27260156	TC71	viability	CTCCTGCTCGCTGCCCTTCTTGG	PRKACA	ENSG00000072062	0.40929044499315936	[1263]	[1715,1773,1744,1976]	8	hSpCas9	negative selection	9387637
14106759	14106782	19	-	27260156	TC71	viability	GAAGATCCTCGACAAACAGAAGG	PRKACA	ENSG00000072062	0.09863927696469743	[279]	[270,303,292,425]	2	hSpCas9	negative selection	9387638
14106858	14106881	19	+	27260156	TC71	viability	TTCGTTCAAACTGATCCAAGTGG	PRKACA	ENSG00000072062	0.028901412560149276	[578]	[639,487,679,728]	0	hSpCas9	negative selection	9387639
14117520	14117543	19	-	27260156	TC32	viability	CAACGCCGCCGCCGCCAAGAAGG	PRKACA	ENSG00000072062	-0.23567140371348905	[123]	[108,50,145,109]	-4	hSpCas9	negative selection	9444630
14106845	14106868	19	-	27260156	TC32	viability	TTTGAACGAATCAAGACCCTCGG	PRKACA	ENSG00000072062	-0.18777064354344097	[451]	[379,341,390,367]	-3	hSpCas9	negative selection	9444631
14106778	14106801	19	+	27260156	TC32	viability	CTTCATGGCATAGTGGTTCCCGG	PRKACA	ENSG00000072062	0.3550411274585683	[536]	[730,274,943,785]	6	hSpCas9	negative selection	9444632
14117506	14117529	19	+	27260156	TC32	viability	CTCCTGCTCGCTGCCCTTCTTGG	PRKACA	ENSG00000072062	0.5374309058339823	[1263]	[1671,1270,2218,1904]	8	hSpCas9	negative selection	9508888
14106759	14106782	19	-	27260156	TC32	viability	GAAGATCCTCGACAAACAGAAGG	PRKACA	ENSG00000072062	0.2674837548731804	[279]	[284,263,414,324]	5	hSpCas9	negative selection	9508889
14106858	14106881	19	+	27260156	TC32	viability	TTCGTTCAAACTGATCCAAGTGG	PRKACA	ENSG00000072062	-0.011302815660519439	[578]	[424,510,762,487]	0	hSpCas9	negative selection	9508890
14097396	14097419	19	+	27869803	HPAFII	viability after 27 days	GCTGGTCTGCGAAGAAGGGCGGG	PRKACA	ENSG00000072062	-2.0733120263461635	[146]	[19,16,NaN]	-8	hSpCas9	negative selection	9565916
14097862	14097885	19	+	27869803	HPAFII	viability after 27 days	GGGCCGCGTAGAAACGGGCATGG	PRKACA	ENSG00000072062	0.4031447690272787	[121]	[164,17,NaN]	3	hSpCas9	negative selection	9565917
14100840	14100863	19	-	27869803	HPAFII	viability after 27 days	AGATGTTCTCACACCTACGGCGG	PRKACA	ENSG00000072062	-0.26881675842779984	[314]	[125,146,NaN]	-2	hSpCas9	negative selection	9565918
14106840	14106863	19	-	27869803	HPAFII	viability after 27 days	ACGAATCAAGACCCTCGGCACGG	PRKACA	ENSG00000072062	-0.45617648861533244	[505]	[254,142,NaN]	-3	hSpCas9	negative selection	9565919
14107334	14107357	19	+	27869803	HPAFII	viability after 27 days	CCCGGCAGCCTTACCTGAGCGGG	PRKACA	ENSG00000072062	-0.5903235669810578	[534]	[182,189,NaN]	-4	hSpCas9	negative selection	9565920
14117519	14117542	19	-	27869803	HPAFII	viability after 27 days	AACGCCGCCGCCGCCAAGAAGGG	PRKACA	ENSG00000072062	0.49544605041316836	[444]	[403,267,NaN]	4	hSpCas9	negative selection	9565922
14097396	14097419	19	+	27869803	HPAFII	viability after 15 days	GCTGGTCTGCGAAGAAGGGCGGG	PRKACA	ENSG00000072062	-1.1760031415105092	[146]	[109,44,NaN]	-8	hSpCas9	negative selection	9648365
14097862	14097885	19	+	27869803	HPAFII	viability after 15 days	GGGCCGCGTAGAAACGGGCATGG	PRKACA	ENSG00000072062	-0.3712100912805618	[121]	[146,72,NaN]	-4	hSpCas9	negative selection	9648366
14100840	14100863	19	-	27869803	HPAFII	viability after 15 days	AGATGTTCTCACACCTACGGCGG	PRKACA	ENSG00000072062	-0.24692498866996448	[314]	[296,277,NaN]	-3	hSpCas9	negative selection	9648367
14106840	14106863	19	-	27869803	HPAFII	viability after 15 days	ACGAATCAAGACCCTCGGCACGG	PRKACA	ENSG00000072062	-0.517608706333633	[505]	[406,362,NaN]	-5	hSpCas9	negative selection	9648368
14107334	14107357	19	+	27869803	HPAFII	viability after 15 days	CCCGGCAGCCTTACCTGAGCGGG	PRKACA	ENSG00000072062	-0.12823232777551263	[534]	[485,550,NaN]	-1	hSpCas9	negative selection	9648369
14117519	14117542	19	-	27869803	HPAFII	viability after 15 days	AACGCCGCCGCCGCCAAGAAGGG	PRKACA	ENSG00000072062	0.5797571617944506	[444]	[1048,506,NaN]	6	hSpCas9	negative selection	9648371
14097396	14097419	19	+	27869803	ASPC1	viability after 36 days	GCTGGTCTGCGAAGAAGGGCGGG	PRKACA	ENSG00000072062	0.6015353723987834	[275]	[327,105,48]	6	hSpCas9	negative selection	9730814
14097862	14097885	19	+	27869803	ASPC1	viability after 36 days	GGGCCGCGTAGAAACGGGCATGG	PRKACA	ENSG00000072062	0.12195196390489074	[562]	[219,115,284]	1	hSpCas9	negative selection	9730815
14100840	14100863	19	-	27869803	ASPC1	viability after 36 days	AGATGTTCTCACACCTACGGCGG	PRKACA	ENSG00000072062	-0.7895713575523581	[900]	[81,161,265]	-6	hSpCas9	negative selection	9730816
14106840	14106863	19	-	27869803	ASPC1	viability after 36 days	ACGAATCAAGACCCTCGGCACGG	PRKACA	ENSG00000072062	0.12953438489809266	[1246]	[715,363,391]	1	hSpCas9	negative selection	9730817
14107334	14107357	19	+	27869803	ASPC1	viability after 36 days	CCCGGCAGCCTTACCTGAGCGGG	PRKACA	ENSG00000072062	0.3853632842075614	[1275]	[804,135,772]	4	hSpCas9	negative selection	9730818
14117519	14117542	19	-	27869803	ASPC1	viability after 36 days	AACGCCGCCGCCGCCAAGAAGGG	PRKACA	ENSG00000072062	0.16125054421815455	[1033]	[648,282,322]	1	hSpCas9	negative selection	9730820
14097396	14097419	19	+	27869803	PATU8988S	viability after 35 days	GCTGGTCTGCGAAGAAGGGCGGG	PRKACA	ENSG00000072062	0.8867622778359963	[314]	[268,199,NaN]	8	hSpCas9	negative selection	9813263
14097862	14097885	19	+	27869803	PATU8988S	viability after 35 days	GGGCCGCGTAGAAACGGGCATGG	PRKACA	ENSG00000072062	-0.24019307560037773	[345]	[108,126,NaN]	-3	hSpCas9	negative selection	9813264
14100840	14100863	19	-	27869803	PATU8988S	viability after 35 days	AGATGTTCTCACACCTACGGCGG	PRKACA	ENSG00000072062	0.6000721184030009	[622]	[306,453,NaN]	6	hSpCas9	negative selection	9813265
14106840	14106863	19	-	27869803	PATU8988S	viability after 35 days	ACGAATCAAGACCCTCGGCACGG	PRKACA	ENSG00000072062	-0.12720320602253843	[1057]	[454,324,NaN]	-1	hSpCas9	negative selection	9813266
14107334	14107357	19	+	27869803	PATU8988S	viability after 35 days	CCCGGCAGCCTTACCTGAGCGGG	PRKACA	ENSG00000072062	-0.3685522336734075	[1263]	[529,257,NaN]	-4	hSpCas9	negative selection	9813267
14117519	14117542	19	-	27869803	PATU8988S	viability after 35 days	AACGCCGCCGCCGCCAAGAAGGG	PRKACA	ENSG00000072062	-0.1625666397829762	[845]	[267,340,NaN]	-2	hSpCas9	negative selection	9813269
14097396	14097419	19	+	27869803	PATU8988S	viability after 31 days	GCTGGTCTGCGAAGAAGGGCGGG	PRKACA	ENSG00000072062	0.3788344624397997	[314]	[172,150,NaN]	4	hSpCas9	negative selection	9895712
14097862	14097885	19	+	27869803	PATU8988S	viability after 31 days	GGGCCGCGTAGAAACGGGCATGG	PRKACA	ENSG00000072062	-0.3753417822106824	[345]	[108,102,NaN]	-4	hSpCas9	negative selection	9895713
14100840	14100863	19	-	27869803	PATU8988S	viability after 31 days	AGATGTTCTCACACCTACGGCGG	PRKACA	ENSG00000072062	0.32444411124522926	[622]	[230,412,NaN]	4	hSpCas9	negative selection	9895714
14106840	14106863	19	-	27869803	PATU8988S	viability after 31 days	ACGAATCAAGACCCTCGGCACGG	PRKACA	ENSG00000072062	-0.1204740960884334	[1057]	[351,433,NaN]	-1	hSpCas9	negative selection	9895715
14107334	14107357	19	+	27869803	PATU8988S	viability after 31 days	CCCGGCAGCCTTACCTGAGCGGG	PRKACA	ENSG00000072062	-0.7567295804042447	[1263]	[358,220,NaN]	-7	hSpCas9	negative selection	9895716
14117519	14117542	19	-	27869803	PATU8988S	viability after 31 days	AACGCCGCCGCCGCCAAGAAGGG	PRKACA	ENSG00000072062	-0.15170191858905124	[845]	[238,385,NaN]	-2	hSpCas9	negative selection	9895718
14097396	14097419	19	+	27869803	HPAFII	viability after 35 days	GCTGGTCTGCGAAGAAGGGCGGG	PRKACA	ENSG00000072062	-2.93848252116382	[146]	[12,5,NaN]	-8	hSpCas9	negative selection	9978161
14097862	14097885	19	+	27869803	HPAFII	viability after 35 days	GGGCCGCGTAGAAACGGGCATGG	PRKACA	ENSG00000072062	0.18673099468869148	[121]	[74,64,NaN]	1	hSpCas9	negative selection	9978162
14100840	14100863	19	-	27869803	HPAFII	viability after 35 days	AGATGTTCTCACACCTACGGCGG	PRKACA	ENSG00000072062	-0.07550835854641491	[314]	[116,189,NaN]	0	hSpCas9	negative selection	9978163
14106840	14106863	19	-	27869803	HPAFII	viability after 35 days	ACGAATCAAGACCCTCGGCACGG	PRKACA	ENSG00000072062	-0.2599177521231053	[505]	[188,241,NaN]	-2	hSpCas9	negative selection	9978164
14107334	14107357	19	+	27869803	HPAFII	viability after 35 days	CCCGGCAGCCTTACCTGAGCGGG	PRKACA	ENSG00000072062	-0.23819855494008224	[534]	[175,289,NaN]	-1	hSpCas9	negative selection	9978165
14117519	14117542	19	-	27869803	HPAFII	viability after 35 days	AACGCCGCCGCCGCCAAGAAGGG	PRKACA	ENSG00000072062	0.4089816662795682	[444]	[411,171,NaN]	2	hSpCas9	negative selection	9978167
14097396	14097419	19	+	27869803	HPAFII	viability after 31 days	GCTGGTCTGCGAAGAAGGGCGGG	PRKACA	ENSG00000072062	-2.1518432436338726	[146]	[19,16,NaN]	-8	hSpCas9	negative selection	10060610
14097862	14097885	19	+	27869803	HPAFII	viability after 31 days	GGGCCGCGTAGAAACGGGCATGG	PRKACA	ENSG00000072062	-0.27427190286461123	[121]	[47,65,NaN]	-2	hSpCas9	negative selection	10060611
14100840	14100863	19	-	27869803	HPAFII	viability after 31 days	AGATGTTCTCACACCTACGGCGG	PRKACA	ENSG00000072062	-0.21967307428781271	[314]	[102,204,NaN]	-1	hSpCas9	negative selection	10060612
14106840	14106863	19	-	27869803	HPAFII	viability after 31 days	ACGAATCAAGACCCTCGGCACGG	PRKACA	ENSG00000072062	-0.4461636887776539	[505]	[139,282,NaN]	-3	hSpCas9	negative selection	10060613
14107334	14107357	19	+	27869803	HPAFII	viability after 31 days	CCCGGCAGCCTTACCTGAGCGGG	PRKACA	ENSG00000072062	-0.46202865114695535	[534]	[127,315,NaN]	-3	hSpCas9	negative selection	10060614
14117519	14117542	19	-	27869803	HPAFII	viability after 31 days	AACGCCGCCGCCGCCAAGAAGGG	PRKACA	ENSG00000072062	0.9069328849749467	[444]	[507,424,NaN]	6	hSpCas9	negative selection	10060616
14106759	14106782	19	-	28162770	P31FUJ	viability	GAAGATCCTCGACAAACAGAAGG	PRKACA	ENSG00000072062	-2.817764705135535	[35]	[5]	-9	hSpCas9	negative selection	10216950
14097395	14097418	19	+	28162770	P31FUJ	viability	GGCTGGTCTGCGAAGAAGGGCGG	PRKACA	ENSG00000072062	-0.03226921704166996	[113]	[130]	0	hSpCas9	negative selection	10216951
14100865	14100888	19	-	28162770	P31FUJ	viability	GTCATGGAGTACGTGCCCGGCGG	PRKACA	ENSG00000072062	-0.814397854037136	[213]	[142]	-6	hSpCas9	negative selection	10216952
14100840	14100863	19	-	28162770	P31FUJ	viability	AGATGTTCTCACACCTACGGCGG	PRKACA	ENSG00000072062	-0.06966636863470543	[141]	[158]	0	hSpCas9	negative selection	10216953
14097406	14097429	19	+	28162770	P31FUJ	viability	GAAGAAGGGCGGGTAGCCAGCGG	PRKACA	ENSG00000072062	-1.2551700174428329	[64]	[31]	-7	hSpCas9	negative selection	10216954
14106840	14106863	19	-	28162770	P31FUJ	viability	ACGAATCAAGACCCTCGGCACGG	PRKACA	ENSG00000072062	-0.5381474151061366	[345]	[279]	-4	hSpCas9	negative selection	10216955
14106826	14106849	19	-	28162770	P31FUJ	viability	TCGGCACGGGCTCCTTCGGGCGG	PRKACA	ENSG00000072062	0.24127288647073253	[400]	[556]	2	hSpCas9	negative selection	10216956
14102821	14102844	19	+	28162770	P31FUJ	viability	AGGAGAACTCGAGTTTGACGAGG	PRKACA	ENSG00000072062	0.7313970741577747	[101]	[198]	8	hSpCas9	negative selection	10216957
14097862	14097885	19	+	28162770	P31FUJ	viability	GGGCCGCGTAGAAACGGGCATGG	PRKACA	ENSG00000072062	0.22176365905110262	[107]	[147]	2	hSpCas9	negative selection	10216958
14097465	14097488	19	-	28162770	P31FUJ	viability	CCAGGGCTACAACAAGGCCGTGG	PRKACA	ENSG00000072062	0.3350867829478359	[84]	[125]	3	hSpCas9	negative selection	10216959
14106759	14106782	19	-	28162770	TF1	viability	GAAGATCCTCGACAAACAGAAGG	PRKACA	ENSG00000072062	NaN	[NaN]	[164]	1	hSpCas9	negative selection	10386316
14097395	14097418	19	+	28162770	TF1	viability	GGCTGGTCTGCGAAGAAGGGCGG	PRKACA	ENSG00000072062	NaN	[NaN]	[76]	1	hSpCas9	negative selection	10386317
14100865	14100888	19	-	28162770	TF1	viability	GTCATGGAGTACGTGCCCGGCGG	PRKACA	ENSG00000072062	NaN	[NaN]	[190]	1	hSpCas9	negative selection	10386318
14100840	14100863	19	-	28162770	TF1	viability	AGATGTTCTCACACCTACGGCGG	PRKACA	ENSG00000072062	NaN	[NaN]	[83]	1	hSpCas9	negative selection	10386319
14097406	14097429	19	+	28162770	TF1	viability	GAAGAAGGGCGGGTAGCCAGCGG	PRKACA	ENSG00000072062	NaN	[NaN]	[17]	1	hSpCas9	negative selection	10386320
14106840	14106863	19	-	28162770	TF1	viability	ACGAATCAAGACCCTCGGCACGG	PRKACA	ENSG00000072062	NaN	[NaN]	[367]	1	hSpCas9	negative selection	10386321
14106826	14106849	19	-	28162770	TF1	viability	TCGGCACGGGCTCCTTCGGGCGG	PRKACA	ENSG00000072062	NaN	[NaN]	[141]	1	hSpCas9	negative selection	10386322
14102821	14102844	19	+	28162770	TF1	viability	AGGAGAACTCGAGTTTGACGAGG	PRKACA	ENSG00000072062	NaN	[NaN]	[100]	1	hSpCas9	negative selection	10386323
14097862	14097885	19	+	28162770	TF1	viability	GGGCCGCGTAGAAACGGGCATGG	PRKACA	ENSG00000072062	NaN	[NaN]	[56]	1	hSpCas9	negative selection	10386324
14097465	14097488	19	-	28162770	TF1	viability	CCAGGGCTACAACAAGGCCGTGG	PRKACA	ENSG00000072062	NaN	[NaN]	[114]	1	hSpCas9	negative selection	10386325
14106759	14106782	19	-	28162770	SKM1	viability	GAAGATCCTCGACAAACAGAAGG	PRKACA	ENSG00000072062	-2.484966710744435	[18]	[5]	-9	hSpCas9	negative selection	10555682
14097395	14097418	19	+	28162770	SKM1	viability	GGCTGGTCTGCGAAGAAGGGCGG	PRKACA	ENSG00000072062	0.9715474245105684	[14]	[51]	8	hSpCas9	negative selection	10555683
14100865	14100888	19	-	28162770	SKM1	viability	GTCATGGAGTACGTGCCCGGCGG	PRKACA	ENSG00000072062	0.6171099362356959	[51]	[140]	6	hSpCas9	negative selection	10555684
14100840	14100863	19	-	28162770	SKM1	viability	AGATGTTCTCACACCTACGGCGG	PRKACA	ENSG00000072062	-0.0025739436638264335	[50]	[89]	0	hSpCas9	negative selection	10555685
14097406	14097429	19	+	28162770	SKM1	viability	GAAGAAGGGCGGGTAGCCAGCGG	PRKACA	ENSG00000072062	-0.4069641987431616	[14]	[19]	-3	hSpCas9	negative selection	10555686
14106840	14106863	19	-	28162770	SKM1	viability	ACGAATCAAGACCCTCGGCACGG	PRKACA	ENSG00000072062	0.4285417636285913	[86]	[206]	4	hSpCas9	negative selection	10555687
14106826	14106849	19	-	28162770	SKM1	viability	TCGGCACGGGCTCCTTCGGGCGG	PRKACA	ENSG00000072062	0.12285674778553357	[79]	[153]	1	hSpCas9	negative selection	10555688
14102821	14102844	19	+	28162770	SKM1	viability	AGGAGAACTCGAGTTTGACGAGG	PRKACA	ENSG00000072062	0.7820696256468551	[24]	[75]	7	hSpCas9	negative selection	10555689
14097862	14097885	19	+	28162770	SKM1	viability	GGGCCGCGTAGAAACGGGCATGG	PRKACA	ENSG00000072062	2.5839906616538313	[9]	[105]	9	hSpCas9	negative selection	10555690
14097465	14097488	19	-	28162770	SKM1	viability	CCAGGGCTACAACAAGGCCGTGG	PRKACA	ENSG00000072062	0.6068416007818689	[12]	[34]	6	hSpCas9	negative selection	10555691
14106759	14106782	19	-	28162770	SKM1	viability	GAAGATCCTCGACAAACAGAAGG	PRKACA	ENSG00000072062	-2.484966710744435	[18]	[5]	-9	hSpCas9	negative selection	10725048
14097395	14097418	19	+	28162770	SKM1	viability	GGCTGGTCTGCGAAGAAGGGCGG	PRKACA	ENSG00000072062	0.9715474245105684	[14]	[51]	8	hSpCas9	negative selection	10725049
14100865	14100888	19	-	28162770	SKM1	viability	GTCATGGAGTACGTGCCCGGCGG	PRKACA	ENSG00000072062	0.6171099362356959	[51]	[140]	6	hSpCas9	negative selection	10725050
14100840	14100863	19	-	28162770	SKM1	viability	AGATGTTCTCACACCTACGGCGG	PRKACA	ENSG00000072062	-0.0025739436638264335	[50]	[89]	0	hSpCas9	negative selection	10725051
14097406	14097429	19	+	28162770	SKM1	viability	GAAGAAGGGCGGGTAGCCAGCGG	PRKACA	ENSG00000072062	-0.4069641987431616	[14]	[19]	-3	hSpCas9	negative selection	10725052
14106840	14106863	19	-	28162770	SKM1	viability	ACGAATCAAGACCCTCGGCACGG	PRKACA	ENSG00000072062	0.4285417636285913	[86]	[206]	4	hSpCas9	negative selection	10725053
14106826	14106849	19	-	28162770	SKM1	viability	TCGGCACGGGCTCCTTCGGGCGG	PRKACA	ENSG00000072062	0.12285674778553357	[79]	[153]	1	hSpCas9	negative selection	10725054
14102821	14102844	19	+	28162770	SKM1	viability	AGGAGAACTCGAGTTTGACGAGG	PRKACA	ENSG00000072062	0.7820696256468551	[24]	[75]	7	hSpCas9	negative selection	10725055
14097862	14097885	19	+	28162770	SKM1	viability	GGGCCGCGTAGAAACGGGCATGG	PRKACA	ENSG00000072062	2.5839906616538313	[9]	[105]	9	hSpCas9	negative selection	10725056
14097465	14097488	19	-	28162770	SKM1	viability	CCAGGGCTACAACAAGGCCGTGG	PRKACA	ENSG00000072062	0.6068416007818689	[12]	[34]	6	hSpCas9	negative selection	10725057
14106759	14106782	19	-	28162770	PL21	viability	GAAGATCCTCGACAAACAGAAGG	PRKACA	ENSG00000072062	0.344529523824495	[37]	[20]	3	hSpCas9	negative selection	10894414
14097395	14097418	19	+	28162770	PL21	viability	GGCTGGTCTGCGAAGAAGGGCGG	PRKACA	ENSG00000072062	-0.22307181623522365	[58]	[21]	-2	hSpCas9	negative selection	10894415
14100865	14100888	19	-	28162770	PL21	viability	GTCATGGAGTACGTGCCCGGCGG	PRKACA	ENSG00000072062	1.471649802390459	[197]	[238]	9	hSpCas9	negative selection	10894416
14100840	14100863	19	-	28162770	PL21	viability	AGATGTTCTCACACCTACGGCGG	PRKACA	ENSG00000072062	0.20709237513108708	[206]	[103]	1	hSpCas9	negative selection	10894417
14097406	14097429	19	+	28162770	PL21	viability	GAAGAAGGGCGGGTAGCCAGCGG	PRKACA	ENSG00000072062	0.8216279912355902	[51]	[39]	7	hSpCas9	negative selection	10894418
14106840	14106863	19	-	28162770	PL21	viability	ACGAATCAAGACCCTCGGCACGG	PRKACA	ENSG00000072062	0.8247511918634763	[322]	[248]	7	hSpCas9	negative selection	10894419
14106826	14106849	19	-	28162770	PL21	viability	TCGGCACGGGCTCCTTCGGGCGG	PRKACA	ENSG00000072062	-0.08143074278190149	[281]	[115]	0	hSpCas9	negative selection	10894420
14102821	14102844	19	+	28162770	PL21	viability	AGGAGAACTCGAGTTTGACGAGG	PRKACA	ENSG00000072062	-0.8557136202441971	[78]	[18]	-5	hSpCas9	negative selection	10894421
14097862	14097885	19	+	28162770	PL21	viability	GGGCCGCGTAGAAACGGGCATGG	PRKACA	ENSG00000072062	0.055749705154145346	[83]	[37]	0	hSpCas9	negative selection	10894422
14097465	14097488	19	-	28162770	PL21	viability	CCAGGGCTACAACAAGGCCGTGG	PRKACA	ENSG00000072062	0.997322731489633	[60]	[52]	8	hSpCas9	negative selection	10894423
14106759	14106782	19	-	28162770	P31FUJ	viability	GAAGATCCTCGACAAACAGAAGG	PRKACA	ENSG00000072062	-2.817764705135535	[35]	[5]	-9	hSpCas9	negative selection	11063780
14097395	14097418	19	+	28162770	P31FUJ	viability	GGCTGGTCTGCGAAGAAGGGCGG	PRKACA	ENSG00000072062	-0.03226921704166996	[113]	[130]	0	hSpCas9	negative selection	11063781
14100865	14100888	19	-	28162770	P31FUJ	viability	GTCATGGAGTACGTGCCCGGCGG	PRKACA	ENSG00000072062	-0.814397854037136	[213]	[142]	-6	hSpCas9	negative selection	11063782
14100840	14100863	19	-	28162770	P31FUJ	viability	AGATGTTCTCACACCTACGGCGG	PRKACA	ENSG00000072062	-0.06966636863470543	[141]	[158]	0	hSpCas9	negative selection	11063783
14097406	14097429	19	+	28162770	P31FUJ	viability	GAAGAAGGGCGGGTAGCCAGCGG	PRKACA	ENSG00000072062	-1.2551700174428329	[64]	[31]	-7	hSpCas9	negative selection	11063784
14106840	14106863	19	-	28162770	P31FUJ	viability	ACGAATCAAGACCCTCGGCACGG	PRKACA	ENSG00000072062	-0.5381474151061366	[345]	[279]	-4	hSpCas9	negative selection	11063785
14106826	14106849	19	-	28162770	P31FUJ	viability	TCGGCACGGGCTCCTTCGGGCGG	PRKACA	ENSG00000072062	0.24127288647073253	[400]	[556]	2	hSpCas9	negative selection	11063786
14102821	14102844	19	+	28162770	P31FUJ	viability	AGGAGAACTCGAGTTTGACGAGG	PRKACA	ENSG00000072062	0.7313970741577747	[101]	[198]	8	hSpCas9	negative selection	11063787
14097862	14097885	19	+	28162770	P31FUJ	viability	GGGCCGCGTAGAAACGGGCATGG	PRKACA	ENSG00000072062	0.22176365905110262	[107]	[147]	2	hSpCas9	negative selection	11063788
14097465	14097488	19	-	28162770	P31FUJ	viability	CCAGGGCTACAACAAGGCCGTGG	PRKACA	ENSG00000072062	0.3350867829478359	[84]	[125]	3	hSpCas9	negative selection	11063789
14106759	14106782	19	-	28162770	OCIAML5	viability	GAAGATCCTCGACAAACAGAAGG	PRKACA	ENSG00000072062	0.782648965054259	[37]	[117]	7	hSpCas9	negative selection	11233146
14097395	14097418	19	+	28162770	OCIAML5	viability	GGCTGGTCTGCGAAGAAGGGCGG	PRKACA	ENSG00000072062	-0.5745325953350882	[32]	[39]	-4	hSpCas9	negative selection	11233147
14100865	14100888	19	-	28162770	OCIAML5	viability	GTCATGGAGTACGTGCCCGGCGG	PRKACA	ENSG00000072062	-1.0908534304511135	[117]	[99]	-6	hSpCas9	negative selection	11233148
14100840	14100863	19	-	28162770	OCIAML5	viability	AGATGTTCTCACACCTACGGCGG	PRKACA	ENSG00000072062	-0.9319198785532115	[129]	[122]	-5	hSpCas9	negative selection	11233149
14097406	14097429	19	+	28162770	OCIAML5	viability	GAAGAAGGGCGGGTAGCCAGCGG	PRKACA	ENSG00000072062	0.0003762407221450381	[35]	[64]	0	hSpCas9	negative selection	11233150
14106840	14106863	19	-	28162770	OCIAML5	viability	ACGAATCAAGACCCTCGGCACGG	PRKACA	ENSG00000072062	-0.2815745529511741	[166]	[247]	-2	hSpCas9	negative selection	11233151
14106826	14106849	19	-	28162770	OCIAML5	viability	TCGGCACGGGCTCCTTCGGGCGG	PRKACA	ENSG00000072062	0.2976805486406852	[159]	[354]	2	hSpCas9	negative selection	11233152
14102821	14102844	19	+	28162770	OCIAML5	viability	AGGAGAACTCGAGTTTGACGAGG	PRKACA	ENSG00000072062	-0.3630284901413763	[56]	[79]	-3	hSpCas9	negative selection	11233153
14097862	14097885	19	+	28162770	OCIAML5	viability	GGGCCGCGTAGAAACGGGCATGG	PRKACA	ENSG00000072062	0.5414147850483992	[58]	[154]	5	hSpCas9	negative selection	11233154
14097465	14097488	19	-	28162770	OCIAML5	viability	CCAGGGCTACAACAAGGCCGTGG	PRKACA	ENSG00000072062	1.3242562017764663	[24]	[112]	9	hSpCas9	negative selection	11233155
14106759	14106782	19	-	28162770	EOL1	viability	GAAGATCCTCGACAAACAGAAGG	PRKACA	ENSG00000072062	0.402126736918091	[78]	[54]	3	hSpCas9	negative selection	11402512
14097395	14097418	19	+	28162770	EOL1	viability	GGCTGGTCTGCGAAGAAGGGCGG	PRKACA	ENSG00000072062	-0.17733184244867894	[87]	[40]	-1	hSpCas9	negative selection	11402513
14100865	14100888	19	-	28162770	EOL1	viability	GTCATGGAGTACGTGCCCGGCGG	PRKACA	ENSG00000072062	0.009159999285475916	[297]	[157]	0	hSpCas9	negative selection	11402514
14100840	14100863	19	-	28162770	EOL1	viability	AGATGTTCTCACACCTACGGCGG	PRKACA	ENSG00000072062	0.3067206369437516	[332]	[216]	3	hSpCas9	negative selection	11402515
14097406	14097429	19	+	28162770	EOL1	viability	GAAGAAGGGCGGGTAGCCAGCGG	PRKACA	ENSG00000072062	-1.224315614343948	[101]	[22]	-7	hSpCas9	negative selection	11402516
14106840	14106863	19	-	28162770	EOL1	viability	ACGAATCAAGACCCTCGGCACGG	PRKACA	ENSG00000072062	0.131673436253672	[569]	[328]	1	hSpCas9	negative selection	11402517
14106826	14106849	19	-	28162770	EOL1	viability	TCGGCACGGGCTCCTTCGGGCGG	PRKACA	ENSG00000072062	0.4415101721738832	[361]	[258]	4	hSpCas9	negative selection	11402518
14102821	14102844	19	+	28162770	EOL1	viability	AGGAGAACTCGAGTTTGACGAGG	PRKACA	ENSG00000072062	-1.0323835065375795	[131]	[33]	-6	hSpCas9	negative selection	11402519
14097862	14097885	19	+	28162770	EOL1	viability	GGGCCGCGTAGAAACGGGCATGG	PRKACA	ENSG00000072062	0.9104725863588116	[102]	[101]	7	hSpCas9	negative selection	11402520
14097465	14097488	19	-	28162770	EOL1	viability	CCAGGGCTACAACAAGGCCGTGG	PRKACA	ENSG00000072062	2.2542532170496163	[73]	[185]	9	hSpCas9	negative selection	11402521
14106759	14106782	19	-	28162770	MOLM13	viability	GAAGATCCTCGACAAACAGAAGG	PRKACA	ENSG00000072062	-0.930659994945696	[86]	[32]	-5	hSpCas9	negative selection	11571878
14097395	14097418	19	+	28162770	MOLM13	viability	GGCTGGTCTGCGAAGAAGGGCGG	PRKACA	ENSG00000072062	-1.4065797363715624	[120]	[32]	-6	hSpCas9	negative selection	11571879
14100865	14100888	19	-	28162770	MOLM13	viability	GTCATGGAGTACGTGCCCGGCGG	PRKACA	ENSG00000072062	0.5881836152622906	[275]	[299]	4	hSpCas9	negative selection	11571880
14100840	14100863	19	-	28162770	MOLM13	viability	AGATGTTCTCACACCTACGGCGG	PRKACA	ENSG00000072062	-0.20290928865588131	[276]	[173]	-1	hSpCas9	negative selection	11571881
14097406	14097429	19	+	28162770	MOLM13	viability	GAAGAAGGGCGGGTAGCCAGCGG	PRKACA	ENSG00000072062	-2.0002594541938272	[82]	[14]	-7	hSpCas9	negative selection	11571882
14106840	14106863	19	-	28162770	MOLM13	viability	ACGAATCAAGACCCTCGGCACGG	PRKACA	ENSG00000072062	0.30123951213512756	[439]	[391]	2	hSpCas9	negative selection	11571883
14106826	14106849	19	-	28162770	MOLM13	viability	TCGGCACGGGCTCCTTCGGGCGG	PRKACA	ENSG00000072062	0.8309866654083454	[303]	[390]	6	hSpCas9	negative selection	11571884
14102821	14102844	19	+	28162770	MOLM13	viability	AGGAGAACTCGAGTTTGACGAGG	PRKACA	ENSG00000072062	1.0410747144893813	[122]	[182]	7	hSpCas9	negative selection	11571885
14097862	14097885	19	+	28162770	MOLM13	viability	GGGCCGCGTAGAAACGGGCATGG	PRKACA	ENSG00000072062	-0.9947375762525252	[112]	[40]	-5	hSpCas9	negative selection	11571886
14097465	14097488	19	-	28162770	MOLM13	viability	CCAGGGCTACAACAAGGCCGTGG	PRKACA	ENSG00000072062	-1.470710073791278	[68]	[17]	-6	hSpCas9	negative selection	11571887
14106759	14106782	19	-	28162770	HEL	viability	GAAGATCCTCGACAAACAGAAGG	PRKACA	ENSG00000072062	-3.357261167999643	[63]	[3]	-9	hSpCas9	negative selection	11741244
14097395	14097418	19	+	28162770	HEL	viability	GGCTGGTCTGCGAAGAAGGGCGG	PRKACA	ENSG00000072062	0.6427388320003569	[74]	[74]	5	hSpCas9	negative selection	11741245
14100865	14100888	19	-	28162770	HEL	viability	GTCATGGAGTACGTGCCCGGCGG	PRKACA	ENSG00000072062	-0.44951967585163166	[225]	[105]	-3	hSpCas9	negative selection	11741246
14100840	14100863	19	-	28162770	HEL	viability	AGATGTTCTCACACCTACGGCGG	PRKACA	ENSG00000072062	-0.12045830373902883	[184]	[108]	-1	hSpCas9	negative selection	11741247
14097406	14097429	19	+	28162770	HEL	viability	GAAGAAGGGCGGGTAGCCAGCGG	PRKACA	ENSG00000072062	-0.5416857391370704	[24]	[10]	-4	hSpCas9	negative selection	11741248
14106840	14106863	19	-	28162770	HEL	viability	ACGAATCAAGACCCTCGGCACGG	PRKACA	ENSG00000072062	-0.13428501408760485	[352]	[205]	-1	hSpCas9	negative selection	11741249
14106826	14106849	19	-	28162770	HEL	viability	TCGGCACGGGCTCCTTCGGGCGG	PRKACA	ENSG00000072062	0.3127434558448798	[268]	[213]	2	hSpCas9	negative selection	11741250
14102821	14102844	19	+	28162770	HEL	viability	AGGAGAACTCGAGTTTGACGAGG	PRKACA	ENSG00000072062	-2.195980260966582	[92]	[12]	-8	hSpCas9	negative selection	11741251
14097862	14097885	19	+	28162770	HEL	viability	GGGCCGCGTAGAAACGGGCATGG	PRKACA	ENSG00000072062	0.7373757061384323	[58]	[62]	6	hSpCas9	negative selection	11741252
14097465	14097488	19	-	28162770	HEL	viability	CCAGGGCTACAACAAGGCCGTGG	PRKACA	ENSG00000072062	-1.4865441849446095	[69]	[15]	-7	hSpCas9	negative selection	11741253
14106759	14106782	19	-	28162770	MV411	viability	GAAGATCCTCGACAAACAGAAGG	PRKACA	ENSG00000072062	0.12879305428415622	[37]	[34]	1	hSpCas9	negative selection	11910610
14097395	14097418	19	+	28162770	MV411	viability	GGCTGGTCTGCGAAGAAGGGCGG	PRKACA	ENSG00000072062	-0.9415962736072414	[56]	[24]	-6	hSpCas9	negative selection	11910611
14100865	14100888	19	-	28162770	MV411	viability	GTCATGGAGTACGTGCCCGGCGG	PRKACA	ENSG00000072062	-1.4067876123754945	[191]	[60]	-7	hSpCas9	negative selection	11910612
14100840	14100863	19	-	28162770	MV411	viability	AGATGTTCTCACACCTACGGCGG	PRKACA	ENSG00000072062	-0.04655366760146391	[178]	[145]	0	hSpCas9	negative selection	11910613
14097406	14097429	19	+	28162770	MV411	viability	GAAGAAGGGCGGGTAGCCAGCGG	PRKACA	ENSG00000072062	-0.8939182984627658	[74]	[33]	-6	hSpCas9	negative selection	11910614
14106840	14106863	19	-	28162770	MV411	viability	ACGAATCAAGACCCTCGGCACGG	PRKACA	ENSG00000072062	-0.19426789895814844	[272]	[200]	-1	hSpCas9	negative selection	11910615
14106826	14106849	19	-	28162770	MV411	viability	TCGGCACGGGCTCCTTCGGGCGG	PRKACA	ENSG00000072062	0.41851532499188626	[277]	[312]	4	hSpCas9	negative selection	11910616
14102821	14102844	19	+	28162770	MV411	viability	AGGAGAACTCGAGTTTGACGAGG	PRKACA	ENSG00000072062	0.2254112444527765	[65]	[64]	2	hSpCas9	negative selection	11910617
14097862	14097885	19	+	28162770	MV411	viability	GGGCCGCGTAGAAACGGGCATGG	PRKACA	ENSG00000072062	0.5386688484472212	[75]	[92]	5	hSpCas9	negative selection	11910618
14097465	14097488	19	-	28162770	MV411	viability	CCAGGGCTACAACAAGGCCGTGG	PRKACA	ENSG00000072062	0.9954583334579774	[77]	[130]	8	hSpCas9	negative selection	11910619
14106759	14106782	19	-	28162770	MONOMAC1	viability	GAAGATCCTCGACAAACAGAAGG	PRKACA	ENSG00000072062	0.6561217646111754	[30]	[55]	6	hSpCas9	negative selection	12079976
14097395	14097418	19	+	28162770	MONOMAC1	viability	GGCTGGTCTGCGAAGAAGGGCGG	PRKACA	ENSG00000072062	0.3203623698489678	[50]	[72]	3	hSpCas9	negative selection	12079977
14100865	14100888	19	-	28162770	MONOMAC1	viability	GTCATGGAGTACGTGCCCGGCGG	PRKACA	ENSG00000072062	0.23685967947060596	[113]	[153]	2	hSpCas9	negative selection	12079978
14100840	14100863	19	-	28162770	MONOMAC1	viability	AGATGTTCTCACACCTACGGCGG	PRKACA	ENSG00000072062	0.1092943927767901	[92]	[114]	1	hSpCas9	negative selection	12079979
14097406	14097429	19	+	28162770	MONOMAC1	viability	GAAGAAGGGCGGGTAGCCAGCGG	PRKACA	ENSG00000072062	-0.14973113228119717	[29]	[30]	-1	hSpCas9	negative selection	12079980
14106840	14106863	19	-	28162770	MONOMAC1	viability	ACGAATCAAGACCCTCGGCACGG	PRKACA	ENSG00000072062	-0.1504942611225234	[182]	[188]	-1	hSpCas9	negative selection	12079981
14106826	14106849	19	-	28162770	MONOMAC1	viability	TCGGCACGGGCTCCTTCGGGCGG	PRKACA	ENSG00000072062	-0.016010852383991248	[186]	[211]	0	hSpCas9	negative selection	12079982
14102821	14102844	19	+	28162770	MONOMAC1	viability	AGGAGAACTCGAGTTTGACGAGG	PRKACA	ENSG00000072062	-1.1774080403106213	[72]	[36]	-7	hSpCas9	negative selection	12079983
14097862	14097885	19	+	28162770	MONOMAC1	viability	GGGCCGCGTAGAAACGGGCATGG	PRKACA	ENSG00000072062	1.672902612376073	[28]	[105]	9	hSpCas9	negative selection	12079984
14097465	14097488	19	-	28162770	MONOMAC1	viability	CCAGGGCTACAACAAGGCCGTGG	PRKACA	ENSG00000072062	-0.5282427555349267	[38]	[30]	-4	hSpCas9	negative selection	12079985
14106759	14106782	19	-	28162770	OCIAML2	viability	GAAGATCCTCGACAAACAGAAGG	PRKACA	ENSG00000072062	-0.16806705522172982	[14]	[73]	-1	hSpCas9	negative selection	12249342
14097395	14097418	19	+	28162770	OCIAML2	viability	GGCTGGTCTGCGAAGAAGGGCGG	PRKACA	ENSG00000072062	-0.5688102191810648	[18]	[70]	-4	hSpCas9	negative selection	12249343
14100865	14100888	19	-	28162770	OCIAML2	viability	GTCATGGAGTACGTGCCCGGCGG	PRKACA	ENSG00000072062	0.9888017933951361	[31]	[351]	8	hSpCas9	negative selection	12249344
14100840	14100863	19	-	28162770	OCIAML2	viability	AGATGTTCTCACACCTACGGCGG	PRKACA	ENSG00000072062	0.05483166373033316	[32]	[189]	0	hSpCas9	negative selection	12249345
14097406	14097429	19	+	28162770	OCIAML2	viability	GAAGAAGGGCGGGTAGCCAGCGG	PRKACA	ENSG00000072062	0.9078817980115687	[9]	[103]	8	hSpCas9	negative selection	12249346
14106840	14106863	19	-	28162770	OCIAML2	viability	ACGAATCAAGACCCTCGGCACGG	PRKACA	ENSG00000072062	0.5325868874413816	[55]	[448]	5	hSpCas9	negative selection	12249347
14106826	14106849	19	-	28162770	OCIAML2	viability	TCGGCACGGGCTCCTTCGGGCGG	PRKACA	ENSG00000072062	1.536864711304763	[35]	[578]	9	hSpCas9	negative selection	12249348
14102821	14102844	19	+	28162770	OCIAML2	viability	AGGAGAACTCGAGTTTGACGAGG	PRKACA	ENSG00000072062	0.7867580174504907	[15]	[152]	7	hSpCas9	negative selection	12249349
14097862	14097885	19	+	28162770	OCIAML2	viability	GGGCCGCGTAGAAACGGGCATGG	PRKACA	ENSG00000072062	0.46796963009369563	[14]	[114]	4	hSpCas9	negative selection	12249350
14097465	14097488	19	-	28162770	OCIAML2	viability	CCAGGGCTACAACAAGGCCGTGG	PRKACA	ENSG00000072062	0.4522023142353788	[11]	[90]	4	hSpCas9	negative selection	12249351
14106759	14106782	19	-	28162770	OCIAML3	viability	GAAGATCCTCGACAAACAGAAGG	PRKACA	ENSG00000072062	0.0434222802911286	[8]	[27]	0	hSpCas9	negative selection	12418708
14097395	14097418	19	+	28162770	OCIAML3	viability	GGCTGGTCTGCGAAGAAGGGCGG	PRKACA	ENSG00000072062	1.8871190494124532	[17]	[200]	9	hSpCas9	negative selection	12418709
14100865	14100888	19	-	28162770	OCIAML3	viability	GTCATGGAGTACGTGCCCGGCGG	PRKACA	ENSG00000072062	-0.16719297326896584	[60]	[163]	-1	hSpCas9	negative selection	12418710
14100840	14100863	19	-	28162770	OCIAML3	viability	AGATGTTCTCACACCTACGGCGG	PRKACA	ENSG00000072062	-0.5769341269652217	[41]	[84]	-4	hSpCas9	negative selection	12418711
14097406	14097429	19	+	28162770	OCIAML3	viability	GAAGAAGGGCGGGTAGCCAGCGG	PRKACA	ENSG00000072062	-1.4565041165742283	[9]	[10]	-7	hSpCas9	negative selection	12418712
14106840	14106863	19	-	28162770	OCIAML3	viability	ACGAATCAAGACCCTCGGCACGG	PRKACA	ENSG00000072062	-0.3118058237524118	[80]	[196]	-2	hSpCas9	negative selection	12418713
14106826	14106849	19	-	28162770	OCIAML3	viability	TCGGCACGGGCTCCTTCGGGCGG	PRKACA	ENSG00000072062	0.11415392519466505	[85]	[280]	1	hSpCas9	negative selection	12418714
14102821	14102844	19	+	28162770	OCIAML3	viability	AGGAGAACTCGAGTTTGACGAGG	PRKACA	ENSG00000072062	-0.09520178335272167	[22]	[64]	0	hSpCas9	negative selection	12418715
14097862	14097885	19	+	28162770	OCIAML3	viability	GGGCCGCGTAGAAACGGGCATGG	PRKACA	ENSG00000072062	-0.36371002090236915	[25]	[60]	-3	hSpCas9	negative selection	12418716
14097465	14097488	19	-	28162770	OCIAML3	viability	CCAGGGCTACAACAAGGCCGTGG	PRKACA	ENSG00000072062	0.2905151422559008	[25]	[95]	2	hSpCas9	negative selection	12418717