Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:5567
• Symbol:PRKACB
• Description:protein kinase cAMP-activated catalytic subunit beta

DataSource: http://genomecrispr.dkfz.de/#!/results/PRKACB

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
84202679	84202702	1	+	26472758	Jiyoye	viability	TCAGGGCTACAATAAGGCAGTGG	PRKACB	ENSG00000142875	1.1379887486904845	[46]	[77]	7	hSpCas9	negative selection	127303
84202695	84202718	1	+	26472758	Jiyoye	viability	GCAGTGGATTGGTGGGCATTAGG	PRKACB	ENSG00000142875	-0.24768913244543891	[147]	[93]	-2	hSpCas9	negative selection	127304
84196667	84196690	1	-	26472758	Jiyoye	viability	AGATGAGGTCTAGTGAATGGAGG	PRKACB	ENSG00000142875	0.44531051039264447	[111]	[114]	3	hSpCas9	negative selection	127305
84196622	84196645	1	-	26472758	Jiyoye	viability	GAGCTGCATAGAACCGTGCATGG	PRKACB	ENSG00000142875	0.617854382278531	[158]	[183]	4	hSpCas9	negative selection	127306
84179217	84179240	1	+	26472758	Jiyoye	viability	AAAATGGGAGAATCCAACTCAGG	PRKACB	ENSG00000142875	2.6659096499060415	[13]	[66]	9	hSpCas9	negative selection	127307
84185120	84185143	1	+	26472758	Jiyoye	viability	GGTTATGGAATATGTCCCTGGGG	PRKACB	ENSG00000142875	0.5540167698351445	[139]	[154]	4	hSpCas9	negative selection	127308
84202750	84202773	1	-	26472758	Jiyoye	viability	TGGTTGGTCTGCAAAGAATGGGG	PRKACB	ENSG00000142875	0.9605678032261596	[153]	[225]	6	hSpCas9	negative selection	127309
84182285	84182308	1	-	26472758	Jiyoye	viability	CATGGCATAATACTGTTCAGTGG	PRKACB	ENSG00000142875	5.451569500864326	[0]	[32]	9	hSpCas9	negative selection	127310
84197741	84197764	1	+	26472758	Jiyoye	viability	GGGTTTGCCAAAAGAGTTAAAGG	PRKACB	ENSG00000142875	-0.6587588886789031	[290]	[138]	-5	hSpCas9	negative selection	127311
84196721	84196744	1	+	26472758	Jiyoye	viability	TGACCATCAAGGCTATATCCAGG	PRKACB	ENSG00000142875	0.054294358289599054	[211]	[165]	0	hSpCas9	negative selection	127312
84202679	84202702	1	+	26472758	KBM7	viability	TCAGGGCTACAATAAGGCAGTGG	PRKACB	ENSG00000142875	-0.18226637660097078	[429,284]	[111,175]	-2	hSpCas9	negative selection	318421
84202695	84202718	1	+	26472758	KBM7	viability	GCAGTGGATTGGTGGGCATTAGG	PRKACB	ENSG00000142875	0.21729999513549858	[732,872]	[416,469]	2	hSpCas9	negative selection	318422
84196667	84196690	1	-	26472758	KBM7	viability	AGATGAGGTCTAGTGAATGGAGG	PRKACB	ENSG00000142875	-0.2580009437186951	[428,366]	[221,96]	-2	hSpCas9	negative selection	318423
84196622	84196645	1	-	26472758	KBM7	viability	GAGCTGCATAGAACCGTGCATGG	PRKACB	ENSG00000142875	0.3208185885421715	[761,727]	[539,347]	3	hSpCas9	negative selection	318424
84179217	84179240	1	+	26472758	KBM7	viability	AAAATGGGAGAATCCAACTCAGG	PRKACB	ENSG00000142875	-0.3562854940937794	[359,261]	[113,111]	-3	hSpCas9	negative selection	318425
84185120	84185143	1	+	26472758	KBM7	viability	GGTTATGGAATATGTCCCTGGGG	PRKACB	ENSG00000142875	0.7636929332064614	[571,365]	[427,313]	8	hSpCas9	negative selection	318426
84202750	84202773	1	-	26472758	KBM7	viability	TGGTTGGTCTGCAAAGAATGGGG	PRKACB	ENSG00000142875	0.7492670256333891	[967,979]	[914,647]	7	hSpCas9	negative selection	318427
84182285	84182308	1	-	26472758	KBM7	viability	CATGGCATAATACTGTTCAGTGG	PRKACB	ENSG00000142875	0.5694947229424303	[216,140]	[154,93]	6	hSpCas9	negative selection	318428
84197741	84197764	1	+	26472758	KBM7	viability	GGGTTTGCCAAAAGAGTTAAAGG	PRKACB	ENSG00000142875	0.48235386423753485	[576,534]	[297,425]	5	hSpCas9	negative selection	318429
84196721	84196744	1	+	26472758	KBM7	viability	TGACCATCAAGGCTATATCCAGG	PRKACB	ENSG00000142875	-0.040698845765031244	[999,1221]	[656,388]	0	hSpCas9	negative selection	318430
84202679	84202702	1	+	26472758	Raji	viability	TCAGGGCTACAATAAGGCAGTGG	PRKACB	ENSG00000142875	0.3459944672681757	[138]	[40]	3	hSpCas9	negative selection	509539
84202695	84202718	1	+	26472758	Raji	viability	GCAGTGGATTGGTGGGCATTAGG	PRKACB	ENSG00000142875	-0.5858318559995802	[497]	[76]	-5	hSpCas9	negative selection	509540
84196667	84196690	1	-	26472758	Raji	viability	AGATGAGGTCTAGTGAATGGAGG	PRKACB	ENSG00000142875	0.6532076421877973	[136]	[49]	6	hSpCas9	negative selection	509541
84196622	84196645	1	-	26472758	Raji	viability	GAGCTGCATAGAACCGTGCATGG	PRKACB	ENSG00000142875	0.37620029380139947	[331]	[99]	3	hSpCas9	negative selection	509542
84179217	84179240	1	+	26472758	Raji	viability	AAAATGGGAGAATCCAACTCAGG	PRKACB	ENSG00000142875	0.33479403147667186	[163]	[47]	3	hSpCas9	negative selection	509543
84185120	84185143	1	+	26472758	Raji	viability	GGTTATGGAATATGTCCCTGGGG	PRKACB	ENSG00000142875	0.3601496057535664	[281]	[83]	3	hSpCas9	negative selection	509544
84202750	84202773	1	-	26472758	Raji	viability	TGGTTGGTCTGCAAAGAATGGGG	PRKACB	ENSG00000142875	0.02302126492959733	[580]	[136]	0	hSpCas9	negative selection	509545
84182285	84182308	1	-	26472758	Raji	viability	CATGGCATAATACTGTTCAGTGG	PRKACB	ENSG00000142875	-0.468645840577549	[160]	[26]	-4	hSpCas9	negative selection	509546
84197741	84197764	1	+	26472758	Raji	viability	GGGTTTGCCAAAAGAGTTAAAGG	PRKACB	ENSG00000142875	-0.04656782986097219	[493]	[110]	0	hSpCas9	negative selection	509547
84196721	84196744	1	+	26472758	Raji	viability	TGACCATCAAGGCTATATCCAGG	PRKACB	ENSG00000142875	0.08823848610689611	[530]	[130]	0	hSpCas9	negative selection	509548
84202679	84202702	1	+	26472758	K562	viability	TCAGGGCTACAATAAGGCAGTGG	PRKACB	ENSG00000142875	1.6484179554928424	[245]	[650]	9	hSpCas9	negative selection	700657
84202695	84202718	1	+	26472758	K562	viability	GCAGTGGATTGGTGGGCATTAGG	PRKACB	ENSG00000142875	0.798810546383167	[778]	[1143]	6	hSpCas9	negative selection	700658
84196667	84196690	1	-	26472758	K562	viability	AGATGAGGTCTAGTGAATGGAGG	PRKACB	ENSG00000142875	1.5699046419669984	[242]	[608]	9	hSpCas9	negative selection	700659
84196622	84196645	1	-	26472758	K562	viability	GAGCTGCATAGAACCGTGCATGG	PRKACB	ENSG00000142875	0.4309659500561729	[651]	[741]	3	hSpCas9	negative selection	700660
84179217	84179240	1	+	26472758	K562	viability	AAAATGGGAGAATCCAACTCAGG	PRKACB	ENSG00000142875	-0.5045195081658351	[241]	[143]	-3	hSpCas9	negative selection	700661
84185120	84185143	1	+	26472758	K562	viability	GGTTATGGAATATGTCCCTGGGG	PRKACB	ENSG00000142875	0.2556751830095701	[382]	[385]	2	hSpCas9	negative selection	700662
84202750	84202773	1	-	26472758	K562	viability	TGGTTGGTCTGCAAAGAATGGGG	PRKACB	ENSG00000142875	0.5733835560159999	[858]	[1078]	4	hSpCas9	negative selection	700663
84182285	84182308	1	-	26472758	K562	viability	CATGGCATAATACTGTTCAGTGG	PRKACB	ENSG00000142875	0.9086701381922423	[117]	[186]	7	hSpCas9	negative selection	700664
84197741	84197764	1	+	26472758	K562	viability	GGGTTTGCCAAAAGAGTTAAAGG	PRKACB	ENSG00000142875	1.3272965423142868	[481]	[1020]	9	hSpCas9	negative selection	700665
84196721	84196744	1	+	26472758	K562	viability	TGACCATCAAGGCTATATCCAGG	PRKACB	ENSG00000142875	0.7281341726183437	[722]	[1010]	6	hSpCas9	negative selection	700666
84078332	84078355	1	+	26627737	DLD1	viability	AACGCGGCGACCGCCAAGAAAGG	PRKACB	ENSG00000142875	1.0453444516740265	[488]	[336,400,225]	8	hSpCas9	negative selection	772731
84144380	84144403	1	-	26627737	DLD1	viability	CCTGTATACTGGTTACAAGGTGG	PRKACB	ENSG00000142875	0.8816017873208385	[562]	[159,394,407]	8	hSpCas9	negative selection	772732
84184108	84184131	1	-	26627737	DLD1	viability	AAGCATACTCCAGTCGAACAAGG	PRKACB	ENSG00000142875	0.5233518487746428	[847]	[384,284,456]	5	hSpCas9	negative selection	772733
84214167	84214190	1	-	26627737	DLD1	viability	CCTTGAGATCTGAACTGAAGTGG	PRKACB	ENSG00000142875	0.30873991969306125	[623]	[230,343,165]	3	hSpCas9	negative selection	772734
84078332	84078355	1	+	26627737	GBM cells	viability after 5 days	AACGCGGCGACCGCCAAGAAAGG	PRKACB	ENSG00000142875	-0.05279056807353322	[469]	[250,234]	-1	hSpCas9	negative selection	855046
84144380	84144403	1	-	26627737	GBM cells	viability after 5 days	CCTGTATACTGGTTACAAGGTGG	PRKACB	ENSG00000142875	-0.3423957597933924	[434]	[164,202]	-5	hSpCas9	negative selection	855047
84184108	84184131	1	-	26627737	GBM cells	viability after 5 days	AAGCATACTCCAGTCGAACAAGG	PRKACB	ENSG00000142875	0.23908767870105785	[439]	[253,302]	4	hSpCas9	negative selection	855048
84214167	84214190	1	-	26627737	GBM cells	viability after 5 days	CCTTGAGATCTGAACTGAAGTGG	PRKACB	ENSG00000142875	-0.304431091713919	[463]	[203,198]	-5	hSpCas9	negative selection	855049
84078332	84078355	1	+	26627737	GBM cells	viability after 13 days	AACGCGGCGACCGCCAAGAAAGG	PRKACB	ENSG00000142875	-0.24883835433877288	[469]	[266,171]	-3	hSpCas9	negative selection	937361
84144380	84144403	1	-	26627737	GBM cells	viability after 13 days	CCTGTATACTGGTTACAAGGTGG	PRKACB	ENSG00000142875	-0.07120488358937938	[434]	[222,225]	-1	hSpCas9	negative selection	937362
84184108	84184131	1	-	26627737	GBM cells	viability after 13 days	AAGCATACTCCAGTCGAACAAGG	PRKACB	ENSG00000142875	0.31180858554638236	[439]	[265,320]	4	hSpCas9	negative selection	937363
84214167	84214190	1	-	26627737	GBM cells	viability after 13 days	CCTTGAGATCTGAACTGAAGTGG	PRKACB	ENSG00000142875	-0.4045713648998152	[463]	[230,156]	-5	hSpCas9	negative selection	937364
84078332	84078355	1	+	26627737	GBM cells	viability after 21 days	AACGCGGCGACCGCCAAGAAAGG	PRKACB	ENSG00000142875	0.20426081218946945	[469]	[289,297]	2	hSpCas9	negative selection	1019676
84144380	84144403	1	-	26627737	GBM cells	viability after 21 days	CCTGTATACTGGTTACAAGGTGG	PRKACB	ENSG00000142875	-0.08050726993711455	[434]	[246,201]	0	hSpCas9	negative selection	1019677
84184108	84184131	1	-	26627737	GBM cells	viability after 21 days	AAGCATACTCCAGTCGAACAAGG	PRKACB	ENSG00000142875	0.4544204548187054	[439]	[349,306]	5	hSpCas9	negative selection	1019678
84214167	84214190	1	-	26627737	GBM cells	viability after 21 days	CCTTGAGATCTGAACTGAAGTGG	PRKACB	ENSG00000142875	-0.17404707261367613	[463]	[224,221]	-1	hSpCas9	negative selection	1019679
84078332	84078355	1	+	26627737	RPE1	viability after 9 days	AACGCGGCGACCGCCAAGAAAGG	PRKACB	ENSG00000142875	0.8664894423091173	[1287]	[732,737]	5	hSpCas9	negative selection	1101991
84144380	84144403	1	-	26627737	RPE1	viability after 9 days	CCTGTATACTGGTTACAAGGTGG	PRKACB	ENSG00000142875	0.17992786382309411	[1141]	[287,555]	1	hSpCas9	negative selection	1101992
84184108	84184131	1	-	26627737	RPE1	viability after 9 days	AAGCATACTCCAGTCGAACAAGG	PRKACB	ENSG00000142875	0.7798578013524557	[1063]	[443,736]	5	hSpCas9	negative selection	1101993
84214167	84214190	1	-	26627737	RPE1	viability after 9 days	CCTTGAGATCTGAACTGAAGTGG	PRKACB	ENSG00000142875	1.459327821875206	[710]	[467,797]	7	hSpCas9	negative selection	1101994
84078332	84078355	1	+	26627737	RPE1	viability after 12 days	AACGCGGCGACCGCCAAGAAAGG	PRKACB	ENSG00000142875	0.7911937805260857	[1287]	[728,460]	5	hSpCas9	negative selection	1184306
84144380	84144403	1	-	26627737	RPE1	viability after 12 days	CCTGTATACTGGTTACAAGGTGG	PRKACB	ENSG00000142875	0.5812046205420891	[1141]	[357,565]	4	hSpCas9	negative selection	1184307
84184108	84184131	1	-	26627737	RPE1	viability after 12 days	AAGCATACTCCAGTCGAACAAGG	PRKACB	ENSG00000142875	0.8742519777093982	[1063]	[489,559]	5	hSpCas9	negative selection	1184308
84214167	84214190	1	-	26627737	RPE1	viability after 12 days	CCTTGAGATCTGAACTGAAGTGG	PRKACB	ENSG00000142875	1.3989493288186554	[710]	[426,584]	7	hSpCas9	negative selection	1184309
84078332	84078355	1	+	26627737	RPE1	viability after 15 days	AACGCGGCGACCGCCAAGAAAGG	PRKACB	ENSG00000142875	0.805853451229868	[1287]	[836,443]	5	hSpCas9	negative selection	1266621
84144380	84144403	1	-	26627737	RPE1	viability after 15 days	CCTGTATACTGGTTACAAGGTGG	PRKACB	ENSG00000142875	0.32597853974571933	[1141]	[379,428]	2	hSpCas9	negative selection	1266622
84184108	84184131	1	-	26627737	RPE1	viability after 15 days	AAGCATACTCCAGTCGAACAAGG	PRKACB	ENSG00000142875	0.8025032666296388	[1063]	[358,684]	5	hSpCas9	negative selection	1266623
84214167	84214190	1	-	26627737	RPE1	viability after 15 days	CCTTGAGATCTGAACTGAAGTGG	PRKACB	ENSG00000142875	1.4907104436301275	[710]	[580,549]	7	hSpCas9	negative selection	1266624
84078332	84078355	1	+	26627737	RPE1	viability after 18 days	AACGCGGCGACCGCCAAGAAAGG	PRKACB	ENSG00000142875	0.8771389091738365	[1287]	[752,515]	5	hSpCas9	negative selection	1348936
84144380	84144403	1	-	26627737	RPE1	viability after 18 days	CCTGTATACTGGTTACAAGGTGG	PRKACB	ENSG00000142875	0.7096283805908359	[1141]	[445,565]	4	hSpCas9	negative selection	1348937
84184108	84184131	1	-	26627737	RPE1	viability after 18 days	AAGCATACTCCAGTCGAACAAGG	PRKACB	ENSG00000142875	0.6529452862296319	[1063]	[392,513]	4	hSpCas9	negative selection	1348938
84214167	84214190	1	-	26627737	RPE1	viability after 18 days	CCTTGAGATCTGAACTGAAGTGG	PRKACB	ENSG00000142875	1.410892320312627	[710]	[486,534]	7	hSpCas9	negative selection	1348939
84078332	84078355	1	+	26627737	HeLa	viability after 8 days	AACGCGGCGACCGCCAAGAAAGG	PRKACB	ENSG00000142875	0.19061298959448647	[575]	[508,138,260]	1	hSpCas9	negative selection	1431251
84144380	84144403	1	-	26627737	HeLa	viability after 8 days	CCTGTATACTGGTTACAAGGTGG	PRKACB	ENSG00000142875	0.7214890089422894	[485]	[369,364,317]	6	hSpCas9	negative selection	1431252
84184108	84184131	1	-	26627737	HeLa	viability after 8 days	AAGCATACTCCAGTCGAACAAGG	PRKACB	ENSG00000142875	0.5210072939555779	[437]	[372,234,236]	4	hSpCas9	negative selection	1431253
84214167	84214190	1	-	26627737	HeLa	viability after 8 days	CCTTGAGATCTGAACTGAAGTGG	PRKACB	ENSG00000142875	0.04192540688467239	[581]	[431,247,147]	0	hSpCas9	negative selection	1431254
84078332	84078355	1	+	26627737	HeLa	viability after 12 days	AACGCGGCGACCGCCAAGAAAGG	PRKACB	ENSG00000142875	0.39336812150857436	[575]	[411,282,248]	3	hSpCas9	negative selection	1513566
84144380	84144403	1	-	26627737	HeLa	viability after 12 days	CCTGTATACTGGTTACAAGGTGG	PRKACB	ENSG00000142875	0.4324330023924044	[485]	[232,242,338]	3	hSpCas9	negative selection	1513567
84184108	84184131	1	-	26627737	HeLa	viability after 12 days	AAGCATACTCCAGTCGAACAAGG	PRKACB	ENSG00000142875	0.14262231493926147	[437]	[217,227,150]	1	hSpCas9	negative selection	1513568
84214167	84214190	1	-	26627737	HeLa	viability after 12 days	CCTTGAGATCTGAACTGAAGTGG	PRKACB	ENSG00000142875	-0.3874023886705751	[581]	[173,139,241]	-3	hSpCas9	negative selection	1513569
84078332	84078355	1	+	26627737	HeLa	viability after 15 days	AACGCGGCGACCGCCAAGAAAGG	PRKACB	ENSG00000142875	1.2389533765071223	[575]	[932,331,376]	8	hSpCas9	negative selection	1595881
84144380	84144403	1	-	26627737	HeLa	viability after 15 days	CCTGTATACTGGTTACAAGGTGG	PRKACB	ENSG00000142875	0.33467359563405846	[485]	[168,349,228]	3	hSpCas9	negative selection	1595882
84184108	84184131	1	-	26627737	HeLa	viability after 15 days	AAGCATACTCCAGTCGAACAAGG	PRKACB	ENSG00000142875	0.671474789213718	[437]	[470,173,197]	5	hSpCas9	negative selection	1595883
84214167	84214190	1	-	26627737	HeLa	viability after 15 days	CCTTGAGATCTGAACTGAAGTGG	PRKACB	ENSG00000142875	-0.08972674805459846	[581]	[273,173,218]	0	hSpCas9	negative selection	1595884
84078332	84078355	1	+	26627737	HeLa	viability after 18 days	AACGCGGCGACCGCCAAGAAAGG	PRKACB	ENSG00000142875	1.2957954394597517	[575]	[653,293,376]	8	hSpCas9	negative selection	1678196
84144380	84144403	1	-	26627737	HeLa	viability after 18 days	CCTGTATACTGGTTACAAGGTGG	PRKACB	ENSG00000142875	0.3208124357904885	[485]	[110,286,228]	2	hSpCas9	negative selection	1678197
84184108	84184131	1	-	26627737	HeLa	viability after 18 days	AAGCATACTCCAGTCGAACAAGG	PRKACB	ENSG00000142875	0.6639154295428084	[437]	[317,137,197]	5	hSpCas9	negative selection	1678198
84214167	84214190	1	-	26627737	HeLa	viability after 18 days	CCTTGAGATCTGAACTGAAGTGG	PRKACB	ENSG00000142875	-0.09408492587789852	[581]	[184,140,218]	-1	hSpCas9	negative selection	1678199
84078332	84078355	1	+	26627737	HCT116	viability after 6 days	AACGCGGCGACCGCCAAGAAAGG	PRKACB	ENSG00000142875	-0.24535185398024661	[1068]	[173,123]	-1	hSpCas9	negative selection	1760511
84144380	84144403	1	-	26627737	HCT116	viability after 6 days	CCTGTATACTGGTTACAAGGTGG	PRKACB	ENSG00000142875	-1.4129334562710323	[793]	[120,5]	-7	hSpCas9	negative selection	1760512
84184108	84184131	1	-	26627737	HCT116	viability after 6 days	AAGCATACTCCAGTCGAACAAGG	PRKACB	ENSG00000142875	-0.12421473608203729	[577]	[132,55]	0	hSpCas9	negative selection	1760513
84214167	84214190	1	-	26627737	HCT116	viability after 6 days	CCTTGAGATCTGAACTGAAGTGG	PRKACB	ENSG00000142875	1.2095203613955323	[670]	[426,142]	6	hSpCas9	negative selection	1760514
84078332	84078355	1	+	26627737	HCT116	viability after 8 days	AACGCGGCGACCGCCAAGAAAGG	PRKACB	ENSG00000142875	0.5519038069790079	[366]	[289,278,319]	5	hSpCas9	negative selection	1842826
84144380	84144403	1	-	26627737	HCT116	viability after 8 days	CCTGTATACTGGTTACAAGGTGG	PRKACB	ENSG00000142875	0.18618823231012438	[557]	[339,333,374]	2	hSpCas9	negative selection	1842827
84184108	84184131	1	-	26627737	HCT116	viability after 8 days	AAGCATACTCCAGTCGAACAAGG	PRKACB	ENSG00000142875	-0.4770788113967837	[568]	[260,239,175]	-5	hSpCas9	negative selection	1842828
84214167	84214190	1	-	26627737	HCT116	viability after 8 days	CCTTGAGATCTGAACTGAAGTGG	PRKACB	ENSG00000142875	0.020604946965993576	[450]	[282,236,236]	0	hSpCas9	negative selection	1842829
84078332	84078355	1	+	26627737	HCT116	viability after 9 days	AACGCGGCGACCGCCAAGAAAGG	PRKACB	ENSG00000142875	0.11331266686253894	[1068]	[310,306]	0	hSpCas9	negative selection	1925141
84144380	84144403	1	-	26627737	HCT116	viability after 9 days	CCTGTATACTGGTTACAAGGTGG	PRKACB	ENSG00000142875	0.7754622567316052	[793]	[668,120]	5	hSpCas9	negative selection	1925142
84184108	84184131	1	-	26627737	HCT116	viability after 9 days	AAGCATACTCCAGTCGAACAAGG	PRKACB	ENSG00000142875	1.3502674393323055	[577]	[445,351]	8	hSpCas9	negative selection	1925143
84214167	84214190	1	-	26627737	HCT116	viability after 9 days	CCTTGAGATCTGAACTGAAGTGG	PRKACB	ENSG00000142875	-0.1495071434410838	[670]	[289,59]	-1	hSpCas9	negative selection	1925144
84078332	84078355	1	+	26627737	HCT116	viability after 12 days	AACGCGGCGACCGCCAAGAAAGG	PRKACB	ENSG00000142875	0.2664653674254313	[366]	[248,211,232]	2	hSpCas9	negative selection	2007456
84144380	84144403	1	-	26627737	HCT116	viability after 12 days	CCTGTATACTGGTTACAAGGTGG	PRKACB	ENSG00000142875	-0.07373289784952675	[557]	[192,219,428]	0	hSpCas9	negative selection	2007457
84184108	84184131	1	-	26627737	HCT116	viability after 12 days	AAGCATACTCCAGTCGAACAAGG	PRKACB	ENSG00000142875	-0.28900612879564325	[568]	[212,367,158]	-3	hSpCas9	negative selection	2007458
84214167	84214190	1	-	26627737	HCT116	viability after 12 days	CCTTGAGATCTGAACTGAAGTGG	PRKACB	ENSG00000142875	-0.5653535926180088	[450]	[129,235,118]	-6	hSpCas9	negative selection	2007459
84078332	84078355	1	+	26627737	HCT116	viability after 15 days	AACGCGGCGACCGCCAAGAAAGG	PRKACB	ENSG00000142875	0.48005702168240877	[366]	[312,256,313]	4	hSpCas9	negative selection	2089771
84144380	84144403	1	-	26627737	HCT116	viability after 15 days	CCTGTATACTGGTTACAAGGTGG	PRKACB	ENSG00000142875	-0.017353337115555756	[557]	[321,184,441]	0	hSpCas9	negative selection	2089772
84184108	84184131	1	-	26627737	HCT116	viability after 15 days	AAGCATACTCCAGTCGAACAAGG	PRKACB	ENSG00000142875	-0.47127815623096236	[568]	[296,215,201]	-5	hSpCas9	negative selection	2089773
84214167	84214190	1	-	26627737	HCT116	viability after 15 days	CCTTGAGATCTGAACTGAAGTGG	PRKACB	ENSG00000142875	-0.17979701559348138	[450]	[229,132,321]	-2	hSpCas9	negative selection	2089774
84078332	84078355	1	+	26627737	HCT116	viability after 18 days	AACGCGGCGACCGCCAAGAAAGG	PRKACB	ENSG00000142875	0.7174589756034568	[366]	[241,373,251]	6	hSpCas9	negative selection	2172086
84144380	84144403	1	-	26627737	HCT116	viability after 18 days	CCTGTATACTGGTTACAAGGTGG	PRKACB	ENSG00000142875	-0.22884413989534091	[557]	[147,131,425]	-2	hSpCas9	negative selection	2172087
84184108	84184131	1	-	26627737	HCT116	viability after 18 days	AAGCATACTCCAGTCGAACAAGG	PRKACB	ENSG00000142875	-0.012486168447021662	[568]	[332,291,187]	0	hSpCas9	negative selection	2172088
84214167	84214190	1	-	26627737	HCT116	viability after 18 days	CCTTGAGATCTGAACTGAAGTGG	PRKACB	ENSG00000142875	-0.7207134691836923	[450]	[131,105,161]	-6	hSpCas9	negative selection	2172089
84182188	84182211	1	+	24336569	HL60	viability	ATTTACATATAGAATAATGCCGG	PRKACB	ENSG00000142875	1.0813188315693962	[179]	[805]	8	hSpCas9	negative selection	2286332
84182236	84182259	1	+	24336569	HL60	viability	ACCCTTGGAACAGGTTCATTTGG	PRKACB	ENSG00000142875	1.4639700359056222	[36]	[215]	8	hSpCas9	negative selection	2286333
84182250	84182273	1	+	24336569	HL60	viability	TTCATTTGGAAGAGTCATGTTGG	PRKACB	ENSG00000142875	0.20421268941418713	[942]	[2298]	2	hSpCas9	negative selection	2286334
84182285	84182308	1	-	24336569	HL60	viability	CATGGCATAATACTGTTCAGTGG	PRKACB	ENSG00000142875	0.1082377018127666	[643]	[1468]	1	hSpCas9	negative selection	2286335
84182303	84182326	1	-	24336569	HL60	viability	CTGCTTATCTAAGATCTTCATGG	PRKACB	ENSG00000142875	0.6706083859275181	[284]	[959]	6	hSpCas9	negative selection	2286336
84185099	84185122	1	+	24336569	HL60	viability	GGATAATTCTAATTTATACATGG	PRKACB	ENSG00000142875	-0.9304263434800765	[298]	[331]	-7	hSpCas9	negative selection	2286337
84185105	84185128	1	+	24336569	HL60	viability	TTCTAATTTATACATGGTTATGG	PRKACB	ENSG00000142875	0.6304712563500252	[249]	[818]	5	hSpCas9	negative selection	2286338
84185118	84185141	1	+	24336569	HL60	viability	ATGGTTATGGAATATGTCCCTGG	PRKACB	ENSG00000142875	0.06495414792878629	[659]	[1460]	0	hSpCas9	negative selection	2286339
84185155	84185178	1	+	24336569	HL60	viability	CACATCTAAGAAGAATTGGAAGG	PRKACB	ENSG00000142875	0.6758758422077169	[1131]	[3826]	6	hSpCas9	negative selection	2286340
84185161	84185184	1	+	24336569	HL60	viability	TAAGAAGAATTGGAAGGTTCAGG	PRKACB	ENSG00000142875	0.30107992428484365	[796]	[2077]	3	hSpCas9	negative selection	2286341
84182188	84182211	1	+	24336569	KBM7	viability	ATTTACATATAGAATAATGCCGG	PRKACB	ENSG00000142875	-0.570298354802016	[465]	[855]	-4	hSpCas9	negative selection	2353509
84182236	84182259	1	+	24336569	KBM7	viability	ACCCTTGGAACAGGTTCATTTGG	PRKACB	ENSG00000142875	1.9545192470224633	[13]	[147]	9	hSpCas9	negative selection	2353510
84182250	84182273	1	+	24336569	KBM7	viability	TTCATTTGGAAGAGTCATGTTGG	PRKACB	ENSG00000142875	0.15306492640454317	[914]	[2774]	1	hSpCas9	negative selection	2353511
84182285	84182308	1	-	24336569	KBM7	viability	CATGGCATAATACTGTTCAGTGG	PRKACB	ENSG00000142875	0.05528222395737997	[469]	[1331]	0	hSpCas9	negative selection	2353512
84182303	84182326	1	-	24336569	KBM7	viability	CTGCTTATCTAAGATCTTCATGG	PRKACB	ENSG00000142875	0.27701784018690534	[409]	[1354]	2	hSpCas9	negative selection	2353513
84185099	84185122	1	+	24336569	KBM7	viability	GGATAATTCTAATTTATACATGG	PRKACB	ENSG00000142875	0.7757330176404547	[111]	[522]	7	hSpCas9	negative selection	2353514
84185105	84185128	1	+	24336569	KBM7	viability	TTCTAATTTATACATGGTTATGG	PRKACB	ENSG00000142875	0.5098907595378179	[283]	[1102]	5	hSpCas9	negative selection	2353515
84185118	84185141	1	+	24336569	KBM7	viability	ATGGTTATGGAATATGTCCCTGG	PRKACB	ENSG00000142875	-0.19767222470070123	[689]	[1640]	-2	hSpCas9	negative selection	2353516
84185155	84185178	1	+	24336569	KBM7	viability	CACATCTAAGAAGAATTGGAAGG	PRKACB	ENSG00000142875	0.27574556154437	[966]	[3192]	2	hSpCas9	negative selection	2353517
84185161	84185184	1	+	24336569	KBM7	viability	TAAGAAGAATTGGAAGGTTCAGG	PRKACB	ENSG00000142875	0.1593616732677683	[607]	[1851]	1	hSpCas9	negative selection	2353518
84223396	84223419	1	+	25494202	A375	resistance to PLX-4720 (puromycin)	TCTCGCTCTGTCGCCCAGGCAAG	PRKACB	ENSG00000142875	-0.2966468943215429	[82,22]	[4,12]	-1	dCas9-VP64	positive selection	2413405
84164246	84164269	1	+	25494202	A375	resistance to PLX-4720 (puromycin)	ATGAAAGCTATCAGCGATCTCGG	PRKACB	ENSG00000142875	-2.09504296119977	[378,101]	[14,7]	-9	dCas9-VP64	positive selection	2413876
84164284	84164307	1	-	25494202	A375	resistance to PLX-4720 (puromycin)	GTGCTGTTGCTAGTGACTATTGG	PRKACB	ENSG00000142875	2.2730129773382126	[68,38]	[102,7]	7	dCas9-VP64	positive selection	2413877
84164213	84164236	1	+	25494202	A375	resistance to PLX-4720 (puromycin)	TGTGCTGCAGTATAGCTTTCTGG	PRKACB	ENSG00000142875	-0.8573647503255613	[33,75]	[1,10]	-5	dCas9-VP64	positive selection	2413878
84164818	84164841	1	+	25494202	A375	resistance to PLX-4720 (puromycin)	CAGTTATGCTTTGCTTCTAGGGG	PRKACB	ENSG00000142875	1.2797429241451552	[19,50]	[6,31]	5	dCas9-VP64	positive selection	2413879
84164895	84164918	1	-	25494202	A375	resistance to PLX-4720 (puromycin)	GATGGTGTAAACACACACACTGG	PRKACB	ENSG00000142875	-0.08145006120095533	[46,159]	[14,28]	0	dCas9-VP64	positive selection	2413880
84164795	84164818	1	+	25494202	A375	resistance to PLX-4720 (puromycin)	TACTAGTGATATCTCATGCTAGG	PRKACB	ENSG00000142875	2.9268656448495936	[153,188]	[7,589]	8	dCas9-VP64	positive selection	2413881
84181525	84181548	1	+	25494202	A375	resistance to PLX-4720 (puromycin)	AAGAGTCTGATTATTGTTCTGGG	PRKACB	ENSG00000142875	-1.9786093343604974	[227,127]	[11,6]	-9	dCas9-VP64	positive selection	2413882
84181448	84181471	1	-	25494202	A375	resistance to PLX-4720 (puromycin)	ACAGCACAGAAGCAAATAATTGG	PRKACB	ENSG00000142875	1.1320617331269827	[25,103]	[57,2]	4	dCas9-VP64	positive selection	2413883
84181532	84181555	1	+	25494202	A375	resistance to PLX-4720 (puromycin)	TGATTATTGTTCTGGGATTCTGG	PRKACB	ENSG00000142875	-1.2563330614283688	[41,208]	[5,15]	-7	dCas9-VP64	positive selection	2413884
84112260	84112283	1	+	25494202	A375	resistance to PLX-4720 (puromycin)	TCTCACTCTGTCTCCCAGGCCGG	PRKACB	ENSG00000142875	-0.22926698104333687	[120,197]	[15,43]	-1	dCas9-VP64	positive selection	2418661
84208021	84208044	1	-	25494202	A375	resistance to PLX-4720 (puromycin)	ACACAAAAATTAGCCGGGCGTGG	PRKACB	ENSG00000142875	-0.8999059485131444	[15,116]	[8,5]	-5	dCas9-VP64	positive selection	2433135
84195836	84195859	1	-	25494202	A375	resistance to PLX-4720 (puromycin)	TCACTGCAAACTCCGCCTCCTGG	PRKACB	ENSG00000142875	-1.1801124495404707	[373,350]	[49,18]	-6	dCas9-VP64	positive selection	2448424
84143980	84144003	1	-	25494202	A375	resistance to PLX-4720 (puromycin)	AAGTCTATGCAAACAACTGAAGG	PRKACB	ENSG00000142875	0.5136441225224472	[62,59]	[16,20]	2	dCas9-VP64	positive selection	2473994
84144122	84144145	1	-	25494202	A375	resistance to PLX-4720 (puromycin)	ACTTGCAATATCTGCCTAAAAGG	PRKACB	ENSG00000142875	-0.8619222521556407	[381,242]	[40,32]	-5	dCas9-VP64	positive selection	2473995
84144110	84144133	1	-	25494202	A375	resistance to PLX-4720 (puromycin)	TGCCTAAAAGGCTTTATGTTTGG	PRKACB	ENSG00000142875	-1.2768639875025662	[438,94]	[31,14]	-7	dCas9-VP64	positive selection	2473996
84223396	84223419	1	+	25494202	A375	resistance to PLX-4720 (zeocin)	TCTCGCTCTGTCGCCCAGGCAAG	PRKACB	ENSG00000142875	1.7427299536741634	[67,144]	[186,48]	8	dCas9-VP64	positive selection	2508660
84164246	84164269	1	+	25494202	A375	resistance to PLX-4720 (zeocin)	ATGAAAGCTATCAGCGATCTCGG	PRKACB	ENSG00000142875	0.46191906491492496	[186,85]	[92,31]	3	dCas9-VP64	positive selection	2509131
84164284	84164307	1	-	25494202	A375	resistance to PLX-4720 (zeocin)	GTGCTGTTGCTAGTGACTATTGG	PRKACB	ENSG00000142875	-0.18042443134464725	[208,499]	[39,158]	-2	dCas9-VP64	positive selection	2509132
84164213	84164236	1	+	25494202	A375	resistance to PLX-4720 (zeocin)	TGTGCTGCAGTATAGCTTTCTGG	PRKACB	ENSG00000142875	-0.3168517455473951	[166,33]	[43,9]	-3	dCas9-VP64	positive selection	2509133
84164818	84164841	1	+	25494202	A375	resistance to PLX-4720 (zeocin)	CAGTTATGCTTTGCTTCTAGGGG	PRKACB	ENSG00000142875	-0.10382080733771927	[81,136]	[32,31]	-1	dCas9-VP64	positive selection	2509134
84164895	84164918	1	-	25494202	A375	resistance to PLX-4720 (zeocin)	GATGGTGTAAACACACACACTGG	PRKACB	ENSG00000142875	1.3283571339453633	[98,89]	[46,105]	7	dCas9-VP64	positive selection	2509135
84164795	84164818	1	+	25494202	A375	resistance to PLX-4720 (zeocin)	TACTAGTGATATCTCATGCTAGG	PRKACB	ENSG00000142875	-0.7262455691206843	[471,265]	[91,54]	-7	dCas9-VP64	positive selection	2509136
84181525	84181548	1	+	25494202	A375	resistance to PLX-4720 (zeocin)	AAGAGTCTGATTATTGTTCTGGG	PRKACB	ENSG00000142875	-0.10716048825553304	[287,140]	[80,49]	-1	dCas9-VP64	positive selection	2509137
84181448	84181471	1	-	25494202	A375	resistance to PLX-4720 (zeocin)	ACAGCACAGAAGCAAATAATTGG	PRKACB	ENSG00000142875	-0.20876228471232713	[224,48]	[60,17]	-2	dCas9-VP64	positive selection	2509138
84181532	84181555	1	+	25494202	A375	resistance to PLX-4720 (zeocin)	TGATTATTGTTCTGGGATTCTGG	PRKACB	ENSG00000142875	-0.5608160690785318	[32,80]	[14,9]	-5	dCas9-VP64	positive selection	2509139
84112260	84112283	1	+	25494202	A375	resistance to PLX-4720 (zeocin)	TCTCACTCTGTCTCCCAGGCCGG	PRKACB	ENSG00000142875	-0.22012594312438807	[153,72]	[52,11]	-2	dCas9-VP64	positive selection	2513916
84208021	84208044	1	-	25494202	A375	resistance to PLX-4720 (zeocin)	ACACAAAAATTAGCCGGGCGTGG	PRKACB	ENSG00000142875	-0.9472939245344096	[73,17]	[10,3]	-8	dCas9-VP64	positive selection	2528390
84195836	84195859	1	-	25494202	A375	resistance to PLX-4720 (zeocin)	TCACTGCAAACTCCGCCTCCTGG	PRKACB	ENSG00000142875	1.4145647280039761	[84,145]	[146,55]	7	dCas9-VP64	positive selection	2543679
84143980	84144003	1	-	25494202	A375	resistance to PLX-4720 (zeocin)	AAGTCTATGCAAACAACTGAAGG	PRKACB	ENSG00000142875	-0.2357365311192785	[177,247]	[62,53]	-2	dCas9-VP64	positive selection	2569249
84144122	84144145	1	-	25494202	A375	resistance to PLX-4720 (zeocin)	ACTTGCAATATCTGCCTAAAAGG	PRKACB	ENSG00000142875	-0.08669946528405248	[261,298]	[95,75]	0	dCas9-VP64	positive selection	2569250
84144110	84144133	1	-	25494202	A375	resistance to PLX-4720 (zeocin)	TGCCTAAAAGGCTTTATGTTTGG	PRKACB	ENSG00000142875	-0.26218426235787473	[383,401]	[125,88]	-2	dCas9-VP64	positive selection	2569251
84182236	84182259	1	+	27013184	SW480	treatment with recombinant TRAIL	ACCCTTGGAACAGGTTCATTTGG	PRKACB	ENSG00000142875	-3.4935821560968923	[298,251]	[15,2]	-9	hSpCas9	positive selection	2961198
84184015	84184038	1	+	27013184	SW480	treatment with recombinant TRAIL	GATATTTATCTCTCAATTACAGG	PRKACB	ENSG00000142875	-1.447606897976025	[63,41]	[3,14]	-6	hSpCas9	positive selection	2961199
84184114	84184137	1	+	27013184	SW480	treatment with recombinant TRAIL	TCGACTGGAGTATGCTTTTAAGG	PRKACB	ENSG00000142875	0.14516055533692662	[615,709]	[294,341]	0	hSpCas9	positive selection	2961200
84185118	84185141	1	+	27013184	SW480	treatment with recombinant TRAIL	ATGGTTATGGAATATGTCCCTGG	PRKACB	ENSG00000142875	1.3423011028678649	[1234,1940]	[1987,1297]	6	hSpCas9	positive selection	2961201
84185119	84185142	1	+	27013184	SW480	treatment with recombinant TRAIL	TGGTTATGGAATATGTCCCTGGG	PRKACB	ENSG00000142875	-0.4822383652798793	[188,190]	[49,70]	-2	hSpCas9	positive selection	2961202
84185120	84185143	1	+	27013184	SW480	treatment with recombinant TRAIL	GGTTATGGAATATGTCCCTGGGG	PRKACB	ENSG00000142875	-0.12217120188942654	[168,159]	[52,82]	0	hSpCas9	positive selection	2961203
84185121	84185144	1	+	27013184	SW480	treatment with recombinant TRAIL	GTTATGGAATATGTCCCTGGGGG	PRKACB	ENSG00000142875	0.7937217825643328	[50,34]	[35,27]	4	hSpCas9	positive selection	2961204
84185151	84185174	1	+	27013184	SW480	treatment with recombinant TRAIL	TTTTCACATCTAAGAAGAATTGG	PRKACB	ENSG00000142875	0.28124994160343475	[73,172]	[14,129]	1	hSpCas9	positive selection	2961205
84185155	84185178	1	+	27013184	SW480	treatment with recombinant TRAIL	CACATCTAAGAAGAATTGGAAGG	PRKACB	ENSG00000142875	1.7764336068682007	[44,104]	[160,29]	7	hSpCas9	positive selection	2961206
84175035	84175058	1	+	27013184	SW480	treatment with recombinant TRAIL	TGCTCCTCTTCAGAAATATCTGG	PRKACB	ENSG00000142875	0.6696882173220642	[107,274]	[42,244]	3	hSpCas9	positive selection	2961207
84164394	84164417	1	+	27013184	SW480	treatment with recombinant TRAIL	GCTCCTTGCCAGGTTCAACATGG	PRKACB	ENSG00000142875	0.43773051643247596	[144,271]	[99,144]	2	hSpCas9	positive selection	2961208
84164395	84164418	1	+	27013184	SW480	treatment with recombinant TRAIL	CTCCTTGCCAGGTTCAACATGGG	PRKACB	ENSG00000142875	1.2598658458976386	[90,115]	[85,133]	6	hSpCas9	positive selection	2961209
84175039	84175062	1	-	27013184	SW480	treatment with recombinant TRAIL	CCTACCAGATATTTCTGAAGAGG	PRKACB	ENSG00000142875	-2.98114167508792	[384,223]	[2,36]	-8	hSpCas9	positive selection	2961210
84175039	84175062	1	+	27013184	SW480	treatment with recombinant TRAIL	CCTCTTCAGAAATATCTGGTAGG	PRKACB	ENSG00000142875	1.1564976930581743	[272,376]	[249,390]	5	hSpCas9	positive selection	2961211
84179192	84179215	1	-	27013184	SW480	treatment with recombinant TRAIL	CAAAAAGTCTTCTTTGGCTTTGG	PRKACB	ENSG00000142875	1.2124738110114626	[1,1]	[1,1]	6	hSpCas9	positive selection	2961212
84179230	84179253	1	-	27013184	SW480	treatment with recombinant TRAIL	TAAATATTCCTTACCTGAGTTGG	PRKACB	ENSG00000142875	-0.2278834523001078	[184,209]	[40,116]	-1	hSpCas9	positive selection	2961213
84182207	84182230	1	-	27013184	SW480	treatment with recombinant TRAIL	CCTTTCAAAATCTTCAAGTCCGG	PRKACB	ENSG00000142875	1.6414339135464693	[64,89]	[120,76]	7	hSpCas9	positive selection	2961214
84182237	84182260	1	-	27013184	SW480	treatment with recombinant TRAIL	TCCAAATGAACCTGTTCCAAGGG	PRKACB	ENSG00000142875	1.328539806333301	[76,26]	[59,56]	6	hSpCas9	positive selection	2961215
84182238	84182261	1	-	27013184	SW480	treatment with recombinant TRAIL	TTCCAAATGAACCTGTTCCAAGG	PRKACB	ENSG00000142875	0.10627067199598861	[110,193]	[64,74]	0	hSpCas9	positive selection	2961216
84182285	84182308	1	-	27013184	SW480	treatment with recombinant TRAIL	CATGGCATAATACTGTTCAGTGG	PRKACB	ENSG00000142875	-5.171432310626037	[156,178]	[1,1]	-9	hSpCas9	positive selection	2961217
84182303	84182326	1	-	27013184	SW480	treatment with recombinant TRAIL	CTGCTTATCTAAGATCTTCATGG	PRKACB	ENSG00000142875	3.6922415452311816	[156,360]	[1510,1227]	9	hSpCas9	positive selection	2961218
84184103	84184126	1	-	27013184	SW480	treatment with recombinant TRAIL	TACTCCAGTCGAACAAGGAAAGG	PRKACB	ENSG00000142875	-0.7484347152586768	[636,847]	[125,276]	-3	hSpCas9	positive selection	2961219
84184108	84184131	1	-	27013184	SW480	treatment with recombinant TRAIL	AAGCATACTCCAGTCGAACAAGG	PRKACB	ENSG00000142875	-4.2746667236875355	[165,171]	[4,1]	-9	hSpCas9	positive selection	2961220
84185081	84185104	1	-	27013184	SW480	treatment with recombinant TRAIL	TATCCTATGAACAAATAAAAAGG	PRKACB	ENSG00000142875	-0.8317050861748431	[130,106]	[31,24]	-4	hSpCas9	positive selection	2961221
84185135	84185158	1	-	27013184	SW480	treatment with recombinant TRAIL	GTGAAAACATTTCACCCCCAGGG	PRKACB	ENSG00000142875	3.090442570115409	[32,17]	[96,94]	9	hSpCas9	positive selection	2961222
84185136	84185159	1	-	27013184	SW480	treatment with recombinant TRAIL	TGTGAAAACATTTCACCCCCAGG	PRKACB	ENSG00000142875	0.9473534906424799	[351,562]	[232,571]	4	hSpCas9	positive selection	2961223
84179217	84179240	1	+	27013184	SW480	treatment with recombinant TRAIL	AAAATGGGAGAATCCAACTCAGG	PRKACB	ENSG00000142875	-0.45060877725456916	[239,202]	[48,100]	-2	hSpCas9	positive selection	2961224
84179222	84179245	1	+	27013184	SW480	treatment with recombinant TRAIL	GGGAGAATCCAACTCAGGTAAGG	PRKACB	ENSG00000142875	-3.0977850816708123	[106,102]	[1,9]	-9	hSpCas9	positive selection	2961225
84182188	84182211	1	+	27013184	SW480	treatment with recombinant TRAIL	ATTTACATATAGAATAATGCCGG	PRKACB	ENSG00000142875	-3.7469529626859828	[100,55]	[2,1]	-9	hSpCas9	positive selection	2961226
84182207	84182230	1	+	27013184	SW480	treatment with recombinant TRAIL	CCGGACTTGAAGATTTTGAAAGG	PRKACB	ENSG00000142875	-3.8700732014606563	[49,88]	[1,1]	-9	hSpCas9	positive selection	2961227
84182285	84182308	1	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CATGGCATAATACTGTTCAGTGG	PRKACB	ENSG00000142875	0.3660548052930355	[3,3]	[2,4]	7	hSpCas9	positive selection	3013623
84078341	84078364	1	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GACCGCCAAGAAAGGCAGCGAGG	PRKACB	ENSG00000142875	-0.14528516128313354	[2,3]	[3,0]	-2	hSpCas9	positive selection	3013624
84185100	84185123	1	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GGATAATTCTAATTTATACATGG	PRKACB	ENSG00000142875	0.09288474004914543	[4,3]	[3,3]	2	hSpCas9	positive selection	3013625
84185135	84185158	1	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GTGAAAACATTTCACCCCCAGGG	PRKACB	ENSG00000142875	-0.5683919580799168	[3,2]	[1,0]	-7	hSpCas9	positive selection	3013626
84182285	84182308	1	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CATGGCATAATACTGTTCAGTGG	PRKACB	ENSG00000142875	0.0976039444410169	[3,3]	[2,2]	1	hSpCas9	positive selection	3081481
84078341	84078364	1	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GACCGCCAAGAAAGGCAGCGAGG	PRKACB	ENSG00000142875	-0.11609631999929546	[2,2]	[2,1]	-2	hSpCas9	positive selection	3081482
84185100	84185123	1	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GGATAATTCTAATTTATACATGG	PRKACB	ENSG00000142875	-0.4481729676962657	[4,4]	[4,0]	-6	hSpCas9	positive selection	3081483
84185135	84185158	1	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GTGAAAACATTTCACCCCCAGGG	PRKACB	ENSG00000142875	-0.15403910379300403	[3,3]	[1,1]	-2	hSpCas9	positive selection	3081484
84182207	84182230		-	24336571	A375	resistance to PLX after 7 days	CCTTTCAAAATCTTCAAGTCCGG	PRKACB	ENSG00000142875	0.20062876871010693	[42,39]	[44,49]	6	hSpCas9	positive selection	3137743
84078316	84078339		+	24336571	A375	resistance to PLX after 7 days	CGCCCCAGACATGGGGAACGCGG	PRKACB	ENSG00000142875	0.18355701130313393	[11,10]	[12,11]	5	hSpCas9	positive selection	3137744
84185136	84185159		-	24336571	A375	resistance to PLX after 7 days	TGTGAAAACATTTCACCCCCAGG	PRKACB	ENSG00000142875	-0.30488308006893083	[45,43]	[35,35]	-8	hSpCas9	positive selection	3137745
84182238	84182261		-	24336571	A375	resistance to PLX after 7 days	TTCCAAATGAACCTGTTCCAAGG	PRKACB	ENSG00000142875	-0.13388254494040774	[59,63]	[56,54]	-4	hSpCas9	positive selection	3137746
84182207	84182230		-	24336571	A375	resistance to PLX after 14 days	CCTTTCAAAATCTTCAAGTCCGG	PRKACB	ENSG00000142875	0.9584138990978821	[36,47]	[36,39]	7	hSpCas9	positive selection	3195536
84078316	84078339		+	24336571	A375	resistance to PLX after 14 days	CGCCCCAGACATGGGGAACGCGG	PRKACB	ENSG00000142875	0.8422197812090941	[13,12]	[10,10]	7	hSpCas9	positive selection	3195537
84185136	84185159		-	24336571	A375	resistance to PLX after 14 days	TGTGAAAACATTTCACCCCCAGG	PRKACB	ENSG00000142875	-0.21687196546862442	[42,44]	[17,16]	-2	hSpCas9	positive selection	3195538
84182238	84182261		-	24336571	A375	resistance to PLX after 14 days	TTCCAAATGAACCTGTTCCAAGG	PRKACB	ENSG00000142875	-0.1815861222403119	[59,66]	[25,24]	-2	hSpCas9	positive selection	3195539
84182207	84182230		-	24336571	A375	viability after 7 days	CCTTTCAAAATCTTCAAGTCCGG	PRKACB	ENSG00000142875	-0.1699107476946644	[48]	[42,39]	-2	hSpCas9	negative selection	3253329
84078316	84078339		+	24336571	A375	viability after 7 days	CGCCCCAGACATGGGGAACGCGG	PRKACB	ENSG00000142875	0.7539627163826967	[6]	[11,10]	9	hSpCas9	negative selection	3253330
84185136	84185159		-	24336571	A375	viability after 7 days	TGTGAAAACATTTCACCCCCAGG	PRKACB	ENSG00000142875	0.21990582696103145	[40]	[45,43]	3	hSpCas9	negative selection	3253331
84182238	84182261		-	24336571	A375	viability after 7 days	TTCCAAATGAACCTGTTCCAAGG	PRKACB	ENSG00000142875	-0.14598097465730087	[71]	[59,63]	-2	hSpCas9	negative selection	3253332
84182207	84182230		-	24336571	A375	viability after 14 days	CCTTTCAAAATCTTCAAGTCCGG	PRKACB	ENSG00000142875	-0.1192040282396234	[48]	[36,47]	-1	hSpCas9	negative selection	3311122
84078316	84078339		+	24336571	A375	viability after 14 days	CGCCCCAGACATGGGGAACGCGG	PRKACB	ENSG00000142875	1.0059549923118885	[6]	[13,12]	9	hSpCas9	negative selection	3311123
84185136	84185159		-	24336571	A375	viability after 14 days	TGTGAAAACATTTCACCCCCAGG	PRKACB	ENSG00000142875	0.20107778516609698	[40]	[42,44]	2	hSpCas9	negative selection	3311124
84182238	84182261		-	24336571	A375	viability after 14 days	TTCCAAATGAACCTGTTCCAAGG	PRKACB	ENSG00000142875	-0.09233282138044174	[71]	[59,66]	-1	hSpCas9	negative selection	3311125
84078340	84078363	1	+	27383988	293T	resistance to West Nile virus (flavivirus)	GACCGCCAAGAAAGGCAGCGAGG	PRKACB	ENSG00000142875	-6.163124681677816e-05	[152,152]	[0,0]	0	hSpCas9	positive selection	3387452
84182303	84182326	1	-	27383988	293T	resistance to West Nile virus (flavivirus)	CTGCTTATCTAAGATCTTCATGG	PRKACB	ENSG00000142875	0.04787284581688529	[147,147]	[0,0]	0	hSpCas9	positive selection	3387453
84185099	84185122	1	+	27383988	293T	resistance to West Nile virus (flavivirus)	GGATAATTCTAATTTATACATGG	PRKACB	ENSG00000142875	1.5568864933047428	[51,51]	[0,0]	6	hSpCas9	positive selection	3387454
84182285	84182308	1	-	26780180	HT29	viability (Avana library 4 designs)	CATGGCATAATACTGTTCAGTGG	PRKACB	ENSG00000142875	0.304320211756796	[]	[]	1	hSpCas9	negative selection	3451808
84078340	84078363	1	+	26780180	HT29	viability (Avana library 4 designs)	GACCGCCAAGAAAGGCAGCGAGG	PRKACB	ENSG00000142875	1.11052967348905	[]	[]	4	hSpCas9	negative selection	3451809
84185099	84185122	1	+	26780180	HT29	viability (Avana library 4 designs)	GGATAATTCTAATTTATACATGG	PRKACB	ENSG00000142875	1.17296578352186	[]	[]	4	hSpCas9	negative selection	3451810
84185135	84185158	1	-	26780180	HT29	viability (Avana library 4 designs)	GTGAAAACATTTCACCCCCAGGG	PRKACB	ENSG00000142875	1.74073372761414	[]	[]	6	hSpCas9	negative selection	3451811
84182285	84182308	1	-	26780180	A375	viability (Avana lentiCRISPRv2)	CATGGCATAATACTGTTCAGTGG	PRKACB	ENSG00000142875	2.57261706453649	[]	[]	4	hSpCas9	negative selection	3547882
84078340	84078363	1	+	26780180	A375	viability (Avana lentiCRISPRv2)	GACCGCCAAGAAAGGCAGCGAGG	PRKACB	ENSG00000142875	7.76515436415935	[]	[]	9	hSpCas9	negative selection	3547883
84185099	84185122	1	+	26780180	A375	viability (Avana lentiCRISPRv2)	GGATAATTCTAATTTATACATGG	PRKACB	ENSG00000142875	-18.7572028320497	[]	[]	-9	hSpCas9	negative selection	3547884
84185135	84185158	1	-	26780180	A375	viability (Avana lentiCRISPRv2)	GTGAAAACATTTCACCCCCAGGG	PRKACB	ENSG00000142875	4.78720009752007	[]	[]	7	hSpCas9	negative selection	3547885
84185121	84185144	1	+	26780180	A375	viability (Avana lentiCRISPRv2)	GTTATGGAATATGTCCCTGGGGG	PRKACB	ENSG00000142875	4.97605258881056	[]	[]	8	hSpCas9	negative selection	3547886
84078350	84078373	1	+	26780180	A375	viability (Avana lentiCRISPRv2)	AAAGGCAGCGAGGTGGAGAGCGG	PRKACB	ENSG00000142875	3.63968669485995	[]	[]	6	hSpCas9	negative selection	3547887
84182285	84182308	1	-	26780180	A375	viability (Avana lentiGuide)	CATGGCATAATACTGTTCAGTGG	PRKACB	ENSG00000142875	-3.59642753278675	[]	[]	-6	hSpCas9	negative selection	3656541
84078340	84078363	1	+	26780180	A375	viability (Avana lentiGuide)	GACCGCCAAGAAAGGCAGCGAGG	PRKACB	ENSG00000142875	-1.16719458555015	[]	[]	-2	hSpCas9	negative selection	3656542
84185099	84185122	1	+	26780180	A375	viability (Avana lentiGuide)	GGATAATTCTAATTTATACATGG	PRKACB	ENSG00000142875	-3.6078416109268	[]	[]	-6	hSpCas9	negative selection	3656543
84185135	84185158	1	-	26780180	A375	viability (Avana lentiGuide)	GTGAAAACATTTCACCCCCAGGG	PRKACB	ENSG00000142875	1.08403608771338	[]	[]	1	hSpCas9	negative selection	3656544
84185121	84185144	1	+	26780180	A375	viability (Avana lentiGuide)	GTTATGGAATATGTCCCTGGGGG	PRKACB	ENSG00000142875	-5.81408751848622	[]	[]	-8	hSpCas9	negative selection	3656545
84078350	84078373	1	+	26780180	A375	viability (Avana lentiGuide)	AAAGGCAGCGAGGTGGAGAGCGG	PRKACB	ENSG00000142875	-1.77678338582678	[]	[]	-3	hSpCas9	negative selection	3656546
84182285	84182308	1	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CATGGCATAATACTGTTCAGTGG	PRKACB	ENSG00000142875	-0.08156581229797236	[5]	[6,3]	-1	hSpCas9	positive selection	3765148
84078340	84078363	1	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GACCGCCAAGAAAGGCAGCGAGG	PRKACB	ENSG00000142875	0.18946290125158965	[3]	[5,3]	5	hSpCas9	positive selection	3765149
84185099	84185122	1	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGATAATTCTAATTTATACATGG	PRKACB	ENSG00000142875	-1.2583757896538557	[10]	[4,2]	-9	hSpCas9	positive selection	3765150
84185135	84185158	1	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GTGAAAACATTTCACCCCCAGGG	PRKACB	ENSG00000142875	0.34415140488127977	[4]	[5,5]	8	hSpCas9	positive selection	3765151
84185121	84185144	1	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GTTATGGAATATGTCCCTGGGGG	PRKACB	ENSG00000142875	0.22988557077464947	[5]	[6,6]	6	hSpCas9	positive selection	3765152
84078350	84078373	1	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AAAGGCAGCGAGGTGGAGAGCGG	PRKACB	ENSG00000142875	0.2561683737464709	[4]	[5,4]	7	hSpCas9	positive selection	3765153
84182285	84182308	1	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CATGGCATAATACTGTTCAGTGG	PRKACB	ENSG00000142875	0.3321914095028722	[5]	[5,5]	8	hSpCas9	positive selection	3873755
84078340	84078363	1	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GACCGCCAAGAAAGGCAGCGAGG	PRKACB	ENSG00000142875	-0.6052888196322508	[4]	[2,2]	-6	hSpCas9	positive selection	3873756
84185099	84185122	1	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGATAATTCTAATTTATACATGG	PRKACB	ENSG00000142875	0.139395690183987	[5]	[5,4]	3	hSpCas9	positive selection	3873757
84185135	84185158	1	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GTGAAAACATTTCACCCCCAGGG	PRKACB	ENSG00000142875	0.05342958694783814	[4]	[3,4]	1	hSpCas9	positive selection	3873758
84185121	84185144	1	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GTTATGGAATATGTCCCTGGGGG	PRKACB	ENSG00000142875	0.2929678154608368	[5]	[5,5]	7	hSpCas9	positive selection	3873759
84078350	84078373	1	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AAAGGCAGCGAGGTGGAGAGCGG	PRKACB	ENSG00000142875	-0.11012552586031922	[4]	[3,3]	-1	hSpCas9	positive selection	3873760
84182236	84182259	1	+	26780180	A375	viability	ACCCTTGGAACAGGTTCATTTGG	PRKACB	ENSG00000142875	0.328643693920585	[]	[]	0	hSpCas9	negative selection	3984207
84078316	84078339	1	+	26780180	A375	viability	CGCCCCAGACATGGGGAACGCGG	PRKACB	ENSG00000142875	0.802134908373794	[]	[]	3	hSpCas9	negative selection	3984208
84182303	84182326	1	-	26780180	A375	viability	CTGCTTATCTAAGATCTTCATGG	PRKACB	ENSG00000142875	0.537542404857698	[]	[]	1	hSpCas9	negative selection	3984209
84078340	84078363	1	+	26780180	A375	viability	GACCGCCAAGAAAGGCAGCGAGG	PRKACB	ENSG00000142875	0.928611827335769	[]	[]	4	hSpCas9	negative selection	3984210
84185099	84185122	1	+	26780180	A375	viability	GGATAATTCTAATTTATACATGG	PRKACB	ENSG00000142875	0.68402984489954	[]	[]	2	hSpCas9	negative selection	3984211
84185136	84185159	1	-	26780180	A375	viability	TGTGAAAACATTTCACCCCCAGG	PRKACB	ENSG00000142875	0.981747773730392	[]	[]	4	hSpCas9	negative selection	3984212
84182236	84182259	1	+	26780180	HT29	viability (GeCKOv2 library)	ACCCTTGGAACAGGTTCATTTGG	PRKACB	ENSG00000142875	0.576966750675939	[]	[]	2	hSpCas9	negative selection	4092173
84078316	84078339	1	+	26780180	HT29	viability (GeCKOv2 library)	CGCCCCAGACATGGGGAACGCGG	PRKACB	ENSG00000142875	1.34275398921358	[]	[]	6	hSpCas9	negative selection	4092174
84182303	84182326	1	-	26780180	HT29	viability (GeCKOv2 library)	CTGCTTATCTAAGATCTTCATGG	PRKACB	ENSG00000142875	0.665370048853206	[]	[]	2	hSpCas9	negative selection	4092175
84078340	84078363	1	+	26780180	HT29	viability (GeCKOv2 library)	GACCGCCAAGAAAGGCAGCGAGG	PRKACB	ENSG00000142875	0.592557492967554	[]	[]	2	hSpCas9	negative selection	4092176
84185099	84185122	1	+	26780180	HT29	viability (GeCKOv2 library)	GGATAATTCTAATTTATACATGG	PRKACB	ENSG00000142875	0.962853586084528	[]	[]	4	hSpCas9	negative selection	4092177
84185136	84185159	1	-	26780180	HT29	viability (GeCKOv2 library)	TGTGAAAACATTTCACCCCCAGG	PRKACB	ENSG00000142875	0.588480381109087	[]	[]	2	hSpCas9	negative selection	4092178
84182207	84182230	1	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CCTTTCAAAATCTTCAAGTCCGG	PRKACB	ENSG00000142875	0.22748465910223092	[5]	[3,5]	6	hSpCas9	positive selection	4162898
84078316	84078339	1	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CGCCCCAGACATGGGGAACGCGG	PRKACB	ENSG00000142875	0.20225057539673638	[3]	[2,3]	5	hSpCas9	positive selection	4162899
84185136	84185159	1	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TGTGAAAACATTTCACCCCCAGG	PRKACB	ENSG00000142875	0.1656385707669456	[5]	[3,4]	4	hSpCas9	positive selection	4162900
84182238	84182261	1	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TTCCAAATGAACCTGTTCCAAGG	PRKACB	ENSG00000142875	0.1964938075044137	[5]	[4,4]	5	hSpCas9	positive selection	4162901
84182207	84182230	1	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CCTTTCAAAATCTTCAAGTCCGG	PRKACB	ENSG00000142875	0.20649289068827764	[5]	[3,3,4,0]	1	hSpCas9	positive selection	4226920
84078316	84078339	1	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CGCCCCAGACATGGGGAACGCGG	PRKACB	ENSG00000142875	0.2099509240506192	[2]	[3,0,0,0]	1	hSpCas9	positive selection	4226921
84185136	84185159	1	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TGTGAAAACATTTCACCCCCAGG	PRKACB	ENSG00000142875	1.2235506003405576	[5]	[4,3,5,5]	8	hSpCas9	positive selection	4226922
84182238	84182261	1	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TTCCAAATGAACCTGTTCCAAGG	PRKACB	ENSG00000142875	1.1018804891420624	[6]	[5,5,6,5]	8	hSpCas9	positive selection	4226923
84078316	84078339	1	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CGCCCCAGACATGGGGAACGCGG	PRKACB	ENSG00000142875	-0.17334554343590836	[1]	[2,0]	-3	hSpCas9	positive selection	4292141
84185136	84185159	1	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TGTGAAAACATTTCACCCCCAGG	PRKACB	ENSG00000142875	0.6607251218421342	[3]	[3,5]	9	hSpCas9	positive selection	4292142
84182236	84182259	1	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ACCCTTGGAACAGGTTCATTTGG	PRKACB	ENSG00000142875	0.44261732263459697	[3]	[4,3]	8	hSpCas9	positive selection	4292143
84078340	84078363	1	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GACCGCCAAGAAAGGCAGCGAGG	PRKACB	ENSG00000142875	0.16599844477312192	[2]	[2,2]	3	hSpCas9	positive selection	4356399
84182303	84182326	1	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CTGCTTATCTAAGATCTTCATGG	PRKACB	ENSG00000142875	0.3261682826266096	[2]	[3,1]	6	hSpCas9	positive selection	4356400
84185099	84185122	1	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GGATAATTCTAATTTATACATGG	PRKACB	ENSG00000142875	0.22823909348040966	[1]	[2,0]	4	hSpCas9	positive selection	4356401
84179218	84179240	1	+	27760321	OCIAML3	viability	AAATGGGAGAATCCAACTCAGG	PRKACB	ENSG00000142875	-0.0474294338850223	[257,169]	[167,148]	0	hSpCas9	negative selection	4430551
84185121	84185143	1	+	27760321	OCIAML3	viability	GTTATGGAATATGTCCCTGGGG	PRKACB	ENSG00000142875	-0.29583380137733584	[137,154]	[64,131]	-3	hSpCas9	negative selection	4430552
84185136	84185158	1	-	27760321	OCIAML3	viability	GTGAAAACATTTCACCCCCAGG	PRKACB	ENSG00000142875	0.6444329886221416	[228,210]	[251,290]	7	hSpCas9	negative selection	4430553
84196622	84196644	1	-	27760321	OCIAML3	viability	AGCTGCATAGAACCGTGCATGG	PRKACB	ENSG00000142875	0.3970863984520112	[811,618]	[685,789]	5	hSpCas9	negative selection	4430554
84196711	84196733	1	+	27760321	OCIAML3	viability	ATCTCTTAATTGACCATCAAGG	PRKACB	ENSG00000142875	0.14450665525068862	[123,118]	[122,81]	1	hSpCas9	negative selection	4430555
84179218	84179240	1	+	27760321	OCIAML2	viability	AAATGGGAGAATCCAACTCAGG	PRKACB	ENSG00000142875	0.28425677348028366	[257,169]	[172,253]	4	hSpCas9	negative selection	4514014
84185121	84185143	1	+	27760321	OCIAML2	viability	GTTATGGAATATGTCCCTGGGG	PRKACB	ENSG00000142875	0.2159331468232797	[137,154]	[111,173]	3	hSpCas9	negative selection	4514015
84185136	84185158	1	-	27760321	OCIAML2	viability	GTGAAAACATTTCACCCCCAGG	PRKACB	ENSG00000142875	1.4214554838513533	[228,210]	[357,632]	9	hSpCas9	negative selection	4514016
84196622	84196644	1	-	27760321	OCIAML2	viability	AGCTGCATAGAACCGTGCATGG	PRKACB	ENSG00000142875	0.325945339153376	[811,618]	[611,861]	4	hSpCas9	negative selection	4514017
84196711	84196733	1	+	27760321	OCIAML2	viability	ATCTCTTAATTGACCATCAAGG	PRKACB	ENSG00000142875	0.014013191784419288	[123,118]	[60,149]	0	hSpCas9	negative selection	4514018
84179218	84179240	1	+	27760321	MV411	viability	AAATGGGAGAATCCAACTCAGG	PRKACB	ENSG00000142875	0.7455795592369225	[257,169]	[179,313]	5	hSpCas9	negative selection	4597477
84185121	84185143	1	+	27760321	MV411	viability	GTTATGGAATATGTCCCTGGGG	PRKACB	ENSG00000142875	0.7182599285672139	[137,154]	[75,286]	5	hSpCas9	negative selection	4597478
84185136	84185158	1	-	27760321	MV411	viability	GTGAAAACATTTCACCCCCAGG	PRKACB	ENSG00000142875	0.17027694754769784	[228,210]	[106,247]	1	hSpCas9	negative selection	4597479
84196622	84196644	1	-	27760321	MV411	viability	AGCTGCATAGAACCGTGCATGG	PRKACB	ENSG00000142875	1.0768309995202363	[811,618]	[1247,597]	7	hSpCas9	negative selection	4597480
84196711	84196733	1	+	27760321	MV411	viability	ATCTCTTAATTGACCATCAAGG	PRKACB	ENSG00000142875	0.19243122892200182	[123,118]	[48,155]	1	hSpCas9	negative selection	4597481
84179218	84179240	1	+	27760321	HL60	viability	AAATGGGAGAATCCAACTCAGG	PRKACB	ENSG00000142875	1.5069717457841638	[257,169]	[525,451]	9	hSpCas9	negative selection	4680940
84185121	84185143	1	+	27760321	HL60	viability	GTTATGGAATATGTCCCTGGGG	PRKACB	ENSG00000142875	-0.6234703517228348	[137,154]	[104,49]	-6	hSpCas9	negative selection	4680941
84185136	84185158	1	-	27760321	HL60	viability	GTGAAAACATTTCACCCCCAGG	PRKACB	ENSG00000142875	1.123740124452001	[228,210]	[294,493]	9	hSpCas9	negative selection	4680942
84196622	84196644	1	-	27760321	HL60	viability	AGCTGCATAGAACCGTGCATGG	PRKACB	ENSG00000142875	0.21267709892489972	[811,618]	[606,740]	2	hSpCas9	negative selection	4680943
84196711	84196733	1	+	27760321	HL60	viability	ATCTCTTAATTGACCATCAAGG	PRKACB	ENSG00000142875	0.9903902229833433	[123,118]	[213,179]	9	hSpCas9	negative selection	4680944
84179218	84179240	1	+	27760321	HT1080	viability	AAATGGGAGAATCCAACTCAGG	PRKACB	ENSG00000142875	0.48355058746249757	[169,132]	[18,155]	2	hSpCas9	negative selection	4764403
84185121	84185143	1	+	27760321	HT1080	viability	GTTATGGAATATGTCCCTGGGG	PRKACB	ENSG00000142875	2.430405471067366	[154,120]	[408,172]	9	hSpCas9	negative selection	4764404
84185136	84185158	1	-	27760321	HT1080	viability	GTGAAAACATTTCACCCCCAGG	PRKACB	ENSG00000142875	-0.27396671211076185	[210,164]	[102,16]	-1	hSpCas9	negative selection	4764405
84196622	84196644	1	-	27760321	HT1080	viability	AGCTGCATAGAACCGTGCATGG	PRKACB	ENSG00000142875	1.0346478971999007	[618,482]	[526,364]	5	hSpCas9	negative selection	4764406
84196711	84196733	1	+	27760321	HT1080	viability	ATCTCTTAATTGACCATCAAGG	PRKACB	ENSG00000142875	-1.9375963947942403	[118,92]	[0,21]	-6	hSpCas9	negative selection	4764407
84179218	84179240	1	+	27760321	HT29	viability after 7 days	AAATGGGAGAATCCAACTCAGG	PRKACB	ENSG00000142875	0.6764820859738077	[169,132]	[377,344,222]	8	hSpCas9	negative selection	4847866
84185121	84185143	1	+	27760321	HT29	viability after 7 days	GTTATGGAATATGTCCCTGGGG	PRKACB	ENSG00000142875	-0.34199906632288957	[154,120]	[150,151,118]	-5	hSpCas9	negative selection	4847867
84185136	84185158	1	-	27760321	HT29	viability after 7 days	GTGAAAACATTTCACCCCCAGG	PRKACB	ENSG00000142875	0.5328901936785083	[210,164]	[514,196,359]	7	hSpCas9	negative selection	4847868
84196622	84196644	1	-	27760321	HT29	viability after 7 days	AGCTGCATAGAACCGTGCATGG	PRKACB	ENSG00000142875	0.35992141797149024	[618,482]	[652,948,1081]	5	hSpCas9	negative selection	4847869
84196711	84196733	1	+	27760321	HT29	viability after 7 days	ATCTCTTAATTGACCATCAAGG	PRKACB	ENSG00000142875	0.3075850965055056	[118,92]	[135,286,80]	5	hSpCas9	negative selection	4847870
84179218	84179240	1	+	27760321	HT29	viability after 25 days	AAATGGGAGAATCCAACTCAGG	PRKACB	ENSG00000142875	0.1621606198355945	[169,132]	[92,225,276]	1	hSpCas9	negative selection	4931329
84185121	84185143	1	+	27760321	HT29	viability after 25 days	GTTATGGAATATGTCCCTGGGG	PRKACB	ENSG00000142875	-0.31867630255656865	[154,120]	[85,140,157]	-3	hSpCas9	negative selection	4931330
84185136	84185158	1	-	27760321	HT29	viability after 25 days	GTGAAAACATTTCACCCCCAGG	PRKACB	ENSG00000142875	0.4511079728188943	[210,164]	[284,279,318]	5	hSpCas9	negative selection	4931331
84196622	84196644	1	-	27760321	HT29	viability after 25 days	AGCTGCATAGAACCGTGCATGG	PRKACB	ENSG00000142875	0.8939811459341637	[618,482]	[1108,1211,1193]	9	hSpCas9	negative selection	4931332
84196711	84196733	1	+	27760321	HT29	viability after 25 days	ATCTCTTAATTGACCATCAAGG	PRKACB	ENSG00000142875	0.33240892175246683	[118,92]	[128,46,297]	3	hSpCas9	negative selection	4931333
84179218	84179240	1	+	27760321	HT29	viability after 22 days	AAATGGGAGAATCCAACTCAGG	PRKACB	ENSG00000142875	-0.006418729152838809	[169,132]	[22,251,252]	0	hSpCas9	negative selection	5014792
84185121	84185143	1	+	27760321	HT29	viability after 22 days	GTTATGGAATATGTCCCTGGGG	PRKACB	ENSG00000142875	-0.3548760265087043	[154,120]	[35,177,162]	-4	hSpCas9	negative selection	5014793
84185136	84185158	1	-	27760321	HT29	viability after 22 days	GTGAAAACATTTCACCCCCAGG	PRKACB	ENSG00000142875	0.5234535139796369	[210,164]	[303,166,467]	6	hSpCas9	negative selection	5014794
84196622	84196644	1	-	27760321	HT29	viability after 22 days	AGCTGCATAGAACCGTGCATGG	PRKACB	ENSG00000142875	0.9983488658208565	[618,482]	[1401,1235,1174]	9	hSpCas9	negative selection	5014795
84196711	84196733	1	+	27760321	HT29	viability after 22 days	ATCTCTTAATTGACCATCAAGG	PRKACB	ENSG00000142875	0.13767212151720898	[118,92]	[34,44,328]	1	hSpCas9	negative selection	5014796
84179218	84179240	1	+	27760321	HT29	viability after 19 days	AAATGGGAGAATCCAACTCAGG	PRKACB	ENSG00000142875	0.3888580317298187	[169,132]	[214,389,79]	4	hSpCas9	negative selection	5098255
84185121	84185143	1	+	27760321	HT29	viability after 19 days	GTTATGGAATATGTCCCTGGGG	PRKACB	ENSG00000142875	0.3044629157800478	[154,120]	[55,102,402]	3	hSpCas9	negative selection	5098256
84185136	84185158	1	-	27760321	HT29	viability after 19 days	GTGAAAACATTTCACCCCCAGG	PRKACB	ENSG00000142875	0.3492766570180843	[210,164]	[449,301,94]	3	hSpCas9	negative selection	5098257
84196622	84196644	1	-	27760321	HT29	viability after 19 days	AGCTGCATAGAACCGTGCATGG	PRKACB	ENSG00000142875	0.5424440676333143	[618,482]	[985,671,1094]	5	hSpCas9	negative selection	5098258
84196711	84196733	1	+	27760321	HT29	viability after 19 days	ATCTCTTAATTGACCATCAAGG	PRKACB	ENSG00000142875	-0.21182382100493324	[118,92]	[60,105,140]	-2	hSpCas9	negative selection	5098259
84179218	84179240	1	+	27760321	HT29	viability after 16 days	AAATGGGAGAATCCAACTCAGG	PRKACB	ENSG00000142875	0.7087798529815714	[169,132]	[297,282,251]	8	hSpCas9	negative selection	5181718
84185121	84185143	1	+	27760321	HT29	viability after 16 days	GTTATGGAATATGTCCCTGGGG	PRKACB	ENSG00000142875	-1.2130839610434263	[154,120]	[32,89,72]	-7	hSpCas9	negative selection	5181719
84185136	84185158	1	-	27760321	HT29	viability after 16 days	GTGAAAACATTTCACCCCCAGG	PRKACB	ENSG00000142875	0.30364084354124854	[210,164]	[212,200,361]	3	hSpCas9	negative selection	5181720
84196622	84196644	1	-	27760321	HT29	viability after 16 days	AGCTGCATAGAACCGTGCATGG	PRKACB	ENSG00000142875	0.6488601844972933	[618,482]	[1019,872,1013]	7	hSpCas9	negative selection	5181721
84196711	84196733	1	+	27760321	HT29	viability after 16 days	ATCTCTTAATTGACCATCAAGG	PRKACB	ENSG00000142875	0.20022803322837435	[118,92]	[138,136,132]	2	hSpCas9	negative selection	5181722
84179218	84179240	1	+	27760321	HT29	viability after 13 days	AAATGGGAGAATCCAACTCAGG	PRKACB	ENSG00000142875	0.41324928043495357	[169,132]	[216,314,173]	5	hSpCas9	negative selection	5265181
84185121	84185143	1	+	27760321	HT29	viability after 13 days	GTTATGGAATATGTCCCTGGGG	PRKACB	ENSG00000142875	-0.057184391365814324	[154,120]	[243,73,143]	0	hSpCas9	negative selection	5265182
84185136	84185158	1	-	27760321	HT29	viability after 13 days	GTGAAAACATTTCACCCCCAGG	PRKACB	ENSG00000142875	0.34489452373634566	[210,164]	[374,215,241]	4	hSpCas9	negative selection	5265183
84196622	84196644	1	-	27760321	HT29	viability after 13 days	AGCTGCATAGAACCGTGCATGG	PRKACB	ENSG00000142875	0.6019685028661598	[618,482]	[1053,831,1020]	7	hSpCas9	negative selection	5265184
84196711	84196733	1	+	27760321	HT29	viability after 13 days	ATCTCTTAATTGACCATCAAGG	PRKACB	ENSG00000142875	0.2674337585680058	[118,92]	[171,140,131]	3	hSpCas9	negative selection	5265185
84179218	84179240	1	+	27760321	HT29	viability after 10 days	AAATGGGAGAATCCAACTCAGG	PRKACB	ENSG00000142875	0.1728689324478938	[169,132]	[90,432,123]	2	hSpCas9	negative selection	5348644
84185121	84185143	1	+	27760321	HT29	viability after 10 days	GTTATGGAATATGTCCCTGGGG	PRKACB	ENSG00000142875	-0.11108748289189174	[154,120]	[154,129,191]	-1	hSpCas9	negative selection	5348645
84185136	84185158	1	-	27760321	HT29	viability after 10 days	GTGAAAACATTTCACCCCCAGG	PRKACB	ENSG00000142875	1.050601850198819	[210,164]	[725,283,443]	9	hSpCas9	negative selection	5348646
84196622	84196644	1	-	27760321	HT29	viability after 10 days	AGCTGCATAGAACCGTGCATGG	PRKACB	ENSG00000142875	0.6889188563703249	[618,482]	[1181,1098,1046]	8	hSpCas9	negative selection	5348647
84196711	84196733	1	+	27760321	HT29	viability after 10 days	ATCTCTTAATTGACCATCAAGG	PRKACB	ENSG00000142875	0.3857451513217347	[118,92]	[198,145,172]	5	hSpCas9	negative selection	5348648
84179218	84179240	1	+	27760321	MOLM13	viability	AAATGGGAGAATCCAACTCAGG	PRKACB	ENSG00000142875	0.4167151634490851	[257,169]	[91,215]	3	hSpCas9	negative selection	5432107
84185121	84185143	1	+	27760321	MOLM13	viability	GTTATGGAATATGTCCCTGGGG	PRKACB	ENSG00000142875	1.9008107460670736	[137,154]	[194,409]	9	hSpCas9	negative selection	5432108
84185136	84185158	1	-	27760321	MOLM13	viability	GTGAAAACATTTCACCCCCAGG	PRKACB	ENSG00000142875	1.7440027469175199	[228,210]	[499,343]	9	hSpCas9	negative selection	5432109
84196622	84196644	1	-	27760321	MOLM13	viability	AGCTGCATAGAACCGTGCATGG	PRKACB	ENSG00000142875	0.695802775616259	[811,618]	[765,548]	5	hSpCas9	negative selection	5432110
84196711	84196733	1	+	27760321	MOLM13	viability	ATCTCTTAATTGACCATCAAGG	PRKACB	ENSG00000142875	-0.22898271053640862	[123,118]	[117,7]	-1	hSpCas9	negative selection	5432111
84144239	84144262	1	+	27661255	K562	viability	GGTTTGAATACCCTGCAAACAGG	PRKACB	ENSG00000142875	-0.007629135121558148	[761,687]	[669,497]	0	dCas9-KRAB	negative selection	5504115
84078316	84078339	1	+	27260156	BXPC3	viability	CGCCCCAGACATGGGGAACGCGG	PRKACB	ENSG00000142875	-0.04350256393674368	[156]	[121,195,134,187]	-1	hSpCas9	negative selection	5564601
84185136	84185159	1	-	27260156	BXPC3	viability	TGTGAAAACATTTCACCCCCAGG	PRKACB	ENSG00000142875	0.40253561691076234	[939]	[939,1369,1579,1342]	8	hSpCas9	negative selection	5564602
84182236	84182259	1	+	27260156	BXPC3	viability	ACCCTTGGAACAGGTTCATTTGG	PRKACB	ENSG00000142875	0.14909380127358718	[805]	[766,921,1038,1036]	3	hSpCas9	negative selection	5564603
84078340	84078363	1	+	27260156	BXPC3	viability	GACCGCCAAGAAAGGCAGCGAGG	PRKACB	ENSG00000142875	-0.030237247923547983	[374]	[276,305,471,511]	0	hSpCas9	negative selection	5628859
84182303	84182326	1	-	27260156	BXPC3	viability	CTGCTTATCTAAGATCTTCATGG	PRKACB	ENSG00000142875	0.28451030843227754	[326]	[351,348,504,476]	6	hSpCas9	negative selection	5628860
84185099	84185122	1	+	27260156	BXPC3	viability	GGATAATTCTAATTTATACATGG	PRKACB	ENSG00000142875	-0.2719916549071526	[148]	[85,147,116,172]	-6	hSpCas9	negative selection	5628861
84078316	84078339	1	+	27260156	A673	viability	CGCCCCAGACATGGGGAACGCGG	PRKACB	ENSG00000142875	-0.051348586299902355	[156]	[181,199,148,196]	-1	hSpCas9	negative selection	5685852
84185136	84185159	1	-	27260156	A673	viability	TGTGAAAACATTTCACCCCCAGG	PRKACB	ENSG00000142875	0.3789295496819658	[939]	[1462,1241,1423,1760]	8	hSpCas9	negative selection	5685853
84182236	84182259	1	+	27260156	A673	viability	ACCCTTGGAACAGGTTCATTTGG	PRKACB	ENSG00000142875	0.18578265027033025	[805]	[1175,1007,1007,1227]	4	hSpCas9	negative selection	5685854
84078340	84078363	1	+	27260156	A673	viability	GACCGCCAAGAAAGGCAGCGAGG	PRKACB	ENSG00000142875	0.019551464687393494	[374]	[548,482,430,366]	0	hSpCas9	negative selection	5750110
84182303	84182326	1	-	27260156	A673	viability	CTGCTTATCTAAGATCTTCATGG	PRKACB	ENSG00000142875	0.312327329350335	[326]	[635,438,366,528]	7	hSpCas9	negative selection	5750111
84185099	84185122	1	+	27260156	A673	viability	GGATAATTCTAATTTATACATGG	PRKACB	ENSG00000142875	0.12351371874988981	[148]	[194,219,165,197]	3	hSpCas9	negative selection	5750112
84078316	84078339	1	+	27260156	A375	viability	CGCCCCAGACATGGGGAACGCGG	PRKACB	ENSG00000142875	-0.0766010265251138	[156]	[103,216,238,143]	-1	hSpCas9	negative selection	5807103
84185136	84185159	1	-	27260156	A375	viability	TGTGAAAACATTTCACCCCCAGG	PRKACB	ENSG00000142875	0.69653524419153	[939]	[2250,1922,1645,1363]	8	hSpCas9	negative selection	5807104
84182236	84182259	1	+	27260156	A375	viability	ACCCTTGGAACAGGTTCATTTGG	PRKACB	ENSG00000142875	0.5487911806913095	[805]	[1578,1742,1285,993]	7	hSpCas9	negative selection	5807105
84078340	84078363	1	+	27260156	A375	viability	GACCGCCAAGAAAGGCAGCGAGG	PRKACB	ENSG00000142875	-0.2057770122659962	[374]	[284,560,342,355]	-3	hSpCas9	negative selection	5871361
84182303	84182326	1	-	27260156	A375	viability	CTGCTTATCTAAGATCTTCATGG	PRKACB	ENSG00000142875	0.6873632087291194	[326]	[531,662,442,802]	8	hSpCas9	negative selection	5871362
84185099	84185122	1	+	27260156	A375	viability	GGATAATTCTAATTTATACATGG	PRKACB	ENSG00000142875	0.5822533442254705	[148]	[248,256,295,240]	8	hSpCas9	negative selection	5871363
84078316	84078339	1	+	27260156	COLO741	viability	CGCCCCAGACATGGGGAACGCGG	PRKACB	ENSG00000142875	0.030748703673996625	[156]	[295,164,163]	0	hSpCas9	negative selection	5928354
84185136	84185159	1	-	27260156	COLO741	viability	TGTGAAAACATTTCACCCCCAGG	PRKACB	ENSG00000142875	0.15299173112879805	[939]	[1415,1064,1514]	3	hSpCas9	negative selection	5928355
84182236	84182259	1	+	27260156	COLO741	viability	ACCCTTGGAACAGGTTCATTTGG	PRKACB	ENSG00000142875	0.1935952916736754	[805]	[1277,1196,1071]	4	hSpCas9	negative selection	5928356
84078340	84078363	1	+	27260156	COLO741	viability	GACCGCCAAGAAAGGCAGCGAGG	PRKACB	ENSG00000142875	-0.6038050045328668	[374]	[242,308,381]	-8	hSpCas9	negative selection	5992612
84182303	84182326	1	-	27260156	COLO741	viability	CTGCTTATCTAAGATCTTCATGG	PRKACB	ENSG00000142875	-0.027275322087161435	[326]	[420,343,460]	0	hSpCas9	negative selection	5992613
84185099	84185122	1	+	27260156	COLO741	viability	GGATAATTCTAATTTATACATGG	PRKACB	ENSG00000142875	-0.26738977094130467	[148]	[159,123,187]	-5	hSpCas9	negative selection	5992614
84078316	84078339	1	+	27260156	CAL120	viability	CGCCCCAGACATGGGGAACGCGG	PRKACB	ENSG00000142875	0.44782964069726194	[156]	[364,229,219]	6	hSpCas9	negative selection	6049605
84185136	84185159	1	-	27260156	CAL120	viability	TGTGAAAACATTTCACCCCCAGG	PRKACB	ENSG00000142875	0.06237988284507745	[939]	[1108,1326,1210]	0	hSpCas9	negative selection	6049606
84182236	84182259	1	+	27260156	CAL120	viability	ACCCTTGGAACAGGTTCATTTGG	PRKACB	ENSG00000142875	-0.017023041866545352	[805]	[1125,1015,853]	0	hSpCas9	negative selection	6049607
84078340	84078363	1	+	27260156	CAL120	viability	GACCGCCAAGAAAGGCAGCGAGG	PRKACB	ENSG00000142875	0.20996430001905086	[374]	[568,434,617]	3	hSpCas9	negative selection	6113863
84182303	84182326	1	-	27260156	CAL120	viability	CTGCTTATCTAAGATCTTCATGG	PRKACB	ENSG00000142875	0.48052355883713826	[326]	[667,644,407]	7	hSpCas9	negative selection	6113864
84185099	84185122	1	+	27260156	CAL120	viability	GGATAATTCTAATTTATACATGG	PRKACB	ENSG00000142875	0.9411352412902015	[148]	[450,154,473]	9	hSpCas9	negative selection	6113865
84078316	84078339	1	+	27260156	CADOES1	viability	CGCCCCAGACATGGGGAACGCGG	PRKACB	ENSG00000142875	0.2936379752752847	[156]	[183,194,181,153]	5	hSpCas9	negative selection	6170856
84185136	84185159	1	-	27260156	CADOES1	viability	TGTGAAAACATTTCACCCCCAGG	PRKACB	ENSG00000142875	0.4090367689844805	[939]	[1299,1005,1268,1063]	6	hSpCas9	negative selection	6170857
84182236	84182259	1	+	27260156	CADOES1	viability	ACCCTTGGAACAGGTTCATTTGG	PRKACB	ENSG00000142875	0.3948746387544644	[805]	[878,908,1234,916]	6	hSpCas9	negative selection	6170858
84078340	84078363	1	+	27260156	CADOES1	viability	GACCGCCAAGAAAGGCAGCGAGG	PRKACB	ENSG00000142875	-0.02533305461391705	[374]	[251,354,345,420]	0	hSpCas9	negative selection	6235114
84182303	84182326	1	-	27260156	CADOES1	viability	CTGCTTATCTAAGATCTTCATGG	PRKACB	ENSG00000142875	0.38060773367244305	[326]	[326,358,446,452]	6	hSpCas9	negative selection	6235115
84185099	84185122	1	+	27260156	CADOES1	viability	GGATAATTCTAATTTATACATGG	PRKACB	ENSG00000142875	0.2547028343901754	[148]	[183,145,197,131]	4	hSpCas9	negative selection	6235116
84078316	84078339	1	+	27260156	EWS502	viability	CGCCCCAGACATGGGGAACGCGG	PRKACB	ENSG00000142875	-0.11703560698266857	[156]	[161,185,87,174]	-2	hSpCas9	negative selection	6292107
84185136	84185159	1	-	27260156	EWS502	viability	TGTGAAAACATTTCACCCCCAGG	PRKACB	ENSG00000142875	0.47687266675068685	[939]	[1246,1203,1378,1757]	8	hSpCas9	negative selection	6292108
84182236	84182259	1	+	27260156	EWS502	viability	ACCCTTGGAACAGGTTCATTTGG	PRKACB	ENSG00000142875	0.40007083835462387	[805]	[1047,1204,1080,1176]	7	hSpCas9	negative selection	6292109
84078340	84078363	1	+	27260156	EWS502	viability	GACCGCCAAGAAAGGCAGCGAGG	PRKACB	ENSG00000142875	0.2954237852090832	[374]	[425,475,389,675]	5	hSpCas9	negative selection	6356365
84182303	84182326	1	-	27260156	EWS502	viability	CTGCTTATCTAAGATCTTCATGG	PRKACB	ENSG00000142875	0.49213410751007075	[326]	[456,507,459,526]	8	hSpCas9	negative selection	6356366
84185099	84185122	1	+	27260156	EWS502	viability	GGATAATTCTAATTTATACATGG	PRKACB	ENSG00000142875	0.16114183166567186	[148]	[127,158,261,162]	3	hSpCas9	negative selection	6356367
84078316	84078339	1	+	27260156	EW8	viability	CGCCCCAGACATGGGGAACGCGG	PRKACB	ENSG00000142875	-0.004439856381076801	[156]	[196,74,57,195]	0	hSpCas9	negative selection	6413358
84185136	84185159	1	-	27260156	EW8	viability	TGTGAAAACATTTCACCCCCAGG	PRKACB	ENSG00000142875	0.3239417808952121	[939]	[1176,1021,822,836]	6	hSpCas9	negative selection	6413359
84182236	84182259	1	+	27260156	EW8	viability	ACCCTTGGAACAGGTTCATTTGG	PRKACB	ENSG00000142875	0.23096796028262623	[805]	[851,755,608,882]	4	hSpCas9	negative selection	6413360
84078340	84078363	1	+	27260156	EW8	viability	GACCGCCAAGAAAGGCAGCGAGG	PRKACB	ENSG00000142875	-0.2955843773696857	[374]	[273,254,251,210]	-5	hSpCas9	negative selection	6477616
84182303	84182326	1	-	27260156	EW8	viability	CTGCTTATCTAAGATCTTCATGG	PRKACB	ENSG00000142875	0.036980507232326765	[326]	[226,379,232,248]	0	hSpCas9	negative selection	6477617
84185099	84185122	1	+	27260156	EW8	viability	GGATAATTCTAATTTATACATGG	PRKACB	ENSG00000142875	-0.05743302366737679	[148]	[118,73,90,183]	-1	hSpCas9	negative selection	6477618
84078316	84078339	1	+	27260156	CORL105	viability	CGCCCCAGACATGGGGAACGCGG	PRKACB	ENSG00000142875	-0.18048879976685872	[156]	[144,155,198,153]	-3	hSpCas9	negative selection	6534609
84185136	84185159	1	-	27260156	CORL105	viability	TGTGAAAACATTTCACCCCCAGG	PRKACB	ENSG00000142875	0.3198407425875851	[939]	[1293,1347,1622,1265]	6	hSpCas9	negative selection	6534610
84182236	84182259	1	+	27260156	CORL105	viability	ACCCTTGGAACAGGTTCATTTGG	PRKACB	ENSG00000142875	0.3514937916465102	[805]	[982,1124,1554,1200]	6	hSpCas9	negative selection	6534611
84078340	84078363	1	+	27260156	CORL105	viability	GACCGCCAAGAAAGGCAGCGAGG	PRKACB	ENSG00000142875	0.004949855151193727	[374]	[374,513,338,513]	0	hSpCas9	negative selection	6598867
84182303	84182326	1	-	27260156	CORL105	viability	CTGCTTATCTAAGATCTTCATGG	PRKACB	ENSG00000142875	0.11649740670344494	[326]	[456,296,587,348]	2	hSpCas9	negative selection	6598868
84185099	84185122	1	+	27260156	CORL105	viability	GGATAATTCTAATTTATACATGG	PRKACB	ENSG00000142875	0.06784960884489188	[148]	[161,164,271,145]	1	hSpCas9	negative selection	6598869
84078316	84078339	1	+	27260156	HS294T	viability	CGCCCCAGACATGGGGAACGCGG	PRKACB	ENSG00000142875	0.6419073705872425	[156]	[58,29,41,284]	8	hSpCas9	negative selection	6655860
84185136	84185159	1	-	27260156	HS294T	viability	TGTGAAAACATTTCACCCCCAGG	PRKACB	ENSG00000142875	0.07329062839809697	[939]	[384,419,337,383]	1	hSpCas9	negative selection	6655861
84182236	84182259	1	+	27260156	HS294T	viability	ACCCTTGGAACAGGTTCATTTGG	PRKACB	ENSG00000142875	0.11606070051316741	[805]	[347,324,354,317]	1	hSpCas9	negative selection	6655862
84078340	84078363	1	+	27260156	HS294T	viability	GACCGCCAAGAAAGGCAGCGAGG	PRKACB	ENSG00000142875	0.23137461234824921	[374]	[108,229,160,186]	3	hSpCas9	negative selection	6720118
84182303	84182326	1	-	27260156	HS294T	viability	CTGCTTATCTAAGATCTTCATGG	PRKACB	ENSG00000142875	-0.09173886271068277	[326]	[86,103,166,119]	-1	hSpCas9	negative selection	6720119
84185099	84185122	1	+	27260156	HS294T	viability	GGATAATTCTAATTTATACATGG	PRKACB	ENSG00000142875	-0.1517866390219016	[148]	[34,39,58,79]	-2	hSpCas9	negative selection	6720120
84078316	84078339	1	+	27260156	HCC44	viability	CGCCCCAGACATGGGGAACGCGG	PRKACB	ENSG00000142875	-0.10357901310577233	[156]	[193,42,289,173]	-2	hSpCas9	negative selection	6777111
84185136	84185159	1	-	27260156	HCC44	viability	TGTGAAAACATTTCACCCCCAGG	PRKACB	ENSG00000142875	0.45838660401571674	[939]	[1785,1275,1434,1387]	7	hSpCas9	negative selection	6777112
84182236	84182259	1	+	27260156	HCC44	viability	ACCCTTGGAACAGGTTCATTTGG	PRKACB	ENSG00000142875	0.3367111934522269	[805]	[1092,881,1792,976]	5	hSpCas9	negative selection	6777113
84078340	84078363	1	+	27260156	HCC44	viability	GACCGCCAAGAAAGGCAGCGAGG	PRKACB	ENSG00000142875	0.328598608187139	[374]	[566,562,521,472]	5	hSpCas9	negative selection	6841369
84182303	84182326	1	-	27260156	HCC44	viability	CTGCTTATCTAAGATCTTCATGG	PRKACB	ENSG00000142875	0.4698154214413861	[326]	[364,355,775,598]	7	hSpCas9	negative selection	6841370
84185099	84185122	1	+	27260156	HCC44	viability	GGATAATTCTAATTTATACATGG	PRKACB	ENSG00000142875	-0.15777118486316533	[148]	[208,124,116,154]	-3	hSpCas9	negative selection	6841371
84078316	84078339	1	+	27260156	G402	viability	CGCCCCAGACATGGGGAACGCGG	PRKACB	ENSG00000142875	-0.42208201944302504	[156]	[123,193,182,73]	-5	hSpCas9	negative selection	6898362
84185136	84185159	1	-	27260156	G402	viability	TGTGAAAACATTTCACCCCCAGG	PRKACB	ENSG00000142875	0.6733021464362872	[939]	[2444,1310,1714,1893]	8	hSpCas9	negative selection	6898363
84182236	84182259	1	+	27260156	G402	viability	ACCCTTGGAACAGGTTCATTTGG	PRKACB	ENSG00000142875	0.38141339201240587	[805]	[1523,778,1258,1549]	5	hSpCas9	negative selection	6898364
84078340	84078363	1	+	27260156	G402	viability	GACCGCCAAGAAAGGCAGCGAGG	PRKACB	ENSG00000142875	0.2905882952923526	[374]	[685,722,416,443]	3	hSpCas9	negative selection	6962620
84182303	84182326	1	-	27260156	G402	viability	CTGCTTATCTAAGATCTTCATGG	PRKACB	ENSG00000142875	0.711338668361712	[326]	[612,422,955,601]	8	hSpCas9	negative selection	6962621
84185099	84185122	1	+	27260156	G402	viability	GGATAATTCTAATTTATACATGG	PRKACB	ENSG00000142875	0.22878034081959164	[148]	[148,431,84,189]	3	hSpCas9	negative selection	6962622
84078316	84078339	1	+	27260156	L33	viability	CGCCCCAGACATGGGGAACGCGG	PRKACB	ENSG00000142875	-0.6294196583421714	[156]	[52,41,83,117]	-9	hSpCas9	negative selection	7019613
84185136	84185159	1	-	27260156	L33	viability	TGTGAAAACATTTCACCCCCAGG	PRKACB	ENSG00000142875	0.31461226396185804	[939]	[1129,564,608,1197]	6	hSpCas9	negative selection	7019614
84182236	84182259	1	+	27260156	L33	viability	ACCCTTGGAACAGGTTCATTTGG	PRKACB	ENSG00000142875	0.2551284295091707	[805]	[897,428,586,969]	5	hSpCas9	negative selection	7019615
84078340	84078363	1	+	27260156	L33	viability	GACCGCCAAGAAAGGCAGCGAGG	PRKACB	ENSG00000142875	-0.17106949601563637	[374]	[230,165,227,335]	-4	hSpCas9	negative selection	7083871
84182303	84182326	1	-	27260156	L33	viability	CTGCTTATCTAAGATCTTCATGG	PRKACB	ENSG00000142875	0.5653847649462721	[326]	[419,175,292,619]	9	hSpCas9	negative selection	7083872
84185099	84185122	1	+	27260156	L33	viability	GGATAATTCTAATTTATACATGG	PRKACB	ENSG00000142875	0.16837894461085035	[148]	[153,49,147,158]	4	hSpCas9	negative selection	7083873
84078316	84078339	1	+	27260156	K562	viability	CGCCCCAGACATGGGGAACGCGG	PRKACB	ENSG00000142875	-0.6672678090121531	[156]	[89,49,160,51]	-7	hSpCas9	negative selection	7140864
84185136	84185159	1	-	27260156	K562	viability	TGTGAAAACATTTCACCCCCAGG	PRKACB	ENSG00000142875	0.5299314326143778	[939]	[1024,1239,1237,1286]	6	hSpCas9	negative selection	7140865
84182236	84182259	1	+	27260156	K562	viability	ACCCTTGGAACAGGTTCATTTGG	PRKACB	ENSG00000142875	0.28252736281624524	[805]	[949,1198,866,524]	3	hSpCas9	negative selection	7140866
84078340	84078363	1	+	27260156	K562	viability	GACCGCCAAGAAAGGCAGCGAGG	PRKACB	ENSG00000142875	0.15354937861412585	[374]	[480,239,377,380]	2	hSpCas9	negative selection	7205122
84182303	84182326	1	-	27260156	K562	viability	CTGCTTATCTAAGATCTTCATGG	PRKACB	ENSG00000142875	0.4443025512354677	[326]	[414,414,313,431]	5	hSpCas9	negative selection	7205123
84185099	84185122	1	+	27260156	K562	viability	GGATAATTCTAATTTATACATGG	PRKACB	ENSG00000142875	-0.155625068234426	[148]	[126,80,32,219]	-2	hSpCas9	negative selection	7205124
84078316	84078339	1	+	27260156	HT29	viability	CGCCCCAGACATGGGGAACGCGG	PRKACB	ENSG00000142875	-0.18221601237267104	[156]	[134,171,145,210]	-4	hSpCas9	negative selection	7262115
84185136	84185159	1	-	27260156	HT29	viability	TGTGAAAACATTTCACCCCCAGG	PRKACB	ENSG00000142875	0.47380089110220536	[939]	[1502,2318,1320,1286]	8	hSpCas9	negative selection	7262116
84182236	84182259	1	+	27260156	HT29	viability	ACCCTTGGAACAGGTTCATTTGG	PRKACB	ENSG00000142875	0.31769501494839036	[805]	[1377,1310,1196,1032]	6	hSpCas9	negative selection	7262117
84078340	84078363	1	+	27260156	HT29	viability	GACCGCCAAGAAAGGCAGCGAGG	PRKACB	ENSG00000142875	0.02460745339159176	[374]	[534,681,350,324]	0	hSpCas9	negative selection	7326373
84182303	84182326	1	-	27260156	HT29	viability	CTGCTTATCTAAGATCTTCATGG	PRKACB	ENSG00000142875	0.3875854205964897	[326]	[497,687,418,487]	7	hSpCas9	negative selection	7326374
84185099	84185122	1	+	27260156	HT29	viability	GGATAATTCTAATTTATACATGG	PRKACB	ENSG00000142875	0.17082146009563637	[148]	[238,195,256,132]	3	hSpCas9	negative selection	7326375
84078316	84078339	1	+	27260156	MHHES1	viability	CGCCCCAGACATGGGGAACGCGG	PRKACB	ENSG00000142875	0.09721970811446456	[156]	[223,253,138,153]	1	hSpCas9	negative selection	7383366
84185136	84185159	1	-	27260156	MHHES1	viability	TGTGAAAACATTTCACCCCCAGG	PRKACB	ENSG00000142875	0.3084488746574223	[939]	[1246,1505,1359,1150]	5	hSpCas9	negative selection	7383367
84182236	84182259	1	+	27260156	MHHES1	viability	ACCCTTGGAACAGGTTCATTTGG	PRKACB	ENSG00000142875	0.3482535303400365	[805]	[1423,1391,946,938]	6	hSpCas9	negative selection	7383368
84078340	84078363	1	+	27260156	MHHES1	viability	GACCGCCAAGAAAGGCAGCGAGG	PRKACB	ENSG00000142875	-0.11119668413368272	[374]	[422,443,428,291]	-2	hSpCas9	negative selection	7447624
84182303	84182326	1	-	27260156	MHHES1	viability	CTGCTTATCTAAGATCTTCATGG	PRKACB	ENSG00000142875	0.1337773760062459	[326]	[602,480,325,261]	2	hSpCas9	negative selection	7447625
84185099	84185122	1	+	27260156	MHHES1	viability	GGATAATTCTAATTTATACATGG	PRKACB	ENSG00000142875	0.22371971971866356	[148]	[196,226,180,180]	4	hSpCas9	negative selection	7447626
84078316	84078339	1	+	27260156	MEWO	viability	CGCCCCAGACATGGGGAACGCGG	PRKACB	ENSG00000142875	0.12838005945653586	[156]	[199,214,73]	3	hSpCas9	negative selection	7504617
84185136	84185159	1	-	27260156	MEWO	viability	TGTGAAAACATTTCACCCCCAGG	PRKACB	ENSG00000142875	0.3203505292087263	[939]	[1242,1114,963]	7	hSpCas9	negative selection	7504618
84182236	84182259	1	+	27260156	MEWO	viability	ACCCTTGGAACAGGTTCATTTGG	PRKACB	ENSG00000142875	0.3800567460545454	[805]	[1035,1056,860]	7	hSpCas9	negative selection	7504619
84078340	84078363	1	+	27260156	MEWO	viability	GACCGCCAAGAAAGGCAGCGAGG	PRKACB	ENSG00000142875	-0.1516944728934344	[374]	[268,380,287]	-3	hSpCas9	negative selection	7568875
84182303	84182326	1	-	27260156	MEWO	viability	CTGCTTATCTAAGATCTTCATGG	PRKACB	ENSG00000142875	-0.006540008335497061	[326]	[353,334,233]	0	hSpCas9	negative selection	7568876
84185099	84185122	1	+	27260156	MEWO	viability	GGATAATTCTAATTTATACATGG	PRKACB	ENSG00000142875	-0.03322455453975737	[148]	[239,84,103]	0	hSpCas9	negative selection	7568877
84078316	84078339	1	+	27260156	LNCAPCLONEFGC	viability	CGCCCCAGACATGGGGAACGCGG	PRKACB	ENSG00000142875	0.7325874880348223	[156]	[208,277,371,103]	9	hSpCas9	negative selection	7625868
84185136	84185159	1	-	27260156	LNCAPCLONEFGC	viability	TGTGAAAACATTTCACCCCCAGG	PRKACB	ENSG00000142875	0.42463876270139544	[939]	[1064,1221,1107,1166]	6	hSpCas9	negative selection	7625869
84182236	84182259	1	+	27260156	LNCAPCLONEFGC	viability	ACCCTTGGAACAGGTTCATTTGG	PRKACB	ENSG00000142875	0.1415446691714547	[805]	[712,813,931,781]	2	hSpCas9	negative selection	7625870
84078340	84078363	1	+	27260156	LNCAPCLONEFGC	viability	GACCGCCAAGAAAGGCAGCGAGG	PRKACB	ENSG00000142875	0.03935628364435628	[374]	[362,366,411,261]	0	hSpCas9	negative selection	7690126
84182303	84182326	1	-	27260156	LNCAPCLONEFGC	viability	CTGCTTATCTAAGATCTTCATGG	PRKACB	ENSG00000142875	0.22110281655924452	[326]	[348,388,318,316]	3	hSpCas9	negative selection	7690127
84185099	84185122	1	+	27260156	LNCAPCLONEFGC	viability	GGATAATTCTAATTTATACATGG	PRKACB	ENSG00000142875	0.08261104877060932	[148]	[173,164,145,84]	1	hSpCas9	negative selection	7690128
84078316	84078339	1	+	27260156	PANC0327	viability	CGCCCCAGACATGGGGAACGCGG	PRKACB	ENSG00000142875	-0.5397747415388765	[156]	[60,94,119,104]	-6	hSpCas9	negative selection	7747119
84185136	84185159	1	-	27260156	PANC0327	viability	TGTGAAAACATTTCACCCCCAGG	PRKACB	ENSG00000142875	0.6413208894251212	[939]	[1777,902,1385,1232]	8	hSpCas9	negative selection	7747120
84182236	84182259	1	+	27260156	PANC0327	viability	ACCCTTGGAACAGGTTCATTTGG	PRKACB	ENSG00000142875	0.36308233506150533	[805]	[1385,657,770,939]	5	hSpCas9	negative selection	7747121
84078340	84078363	1	+	27260156	PANC0327	viability	GACCGCCAAGAAAGGCAGCGAGG	PRKACB	ENSG00000142875	0.3198900162571999	[374]	[334,296,553,485]	5	hSpCas9	negative selection	7811377
84182303	84182326	1	-	27260156	PANC0327	viability	CTGCTTATCTAAGATCTTCATGG	PRKACB	ENSG00000142875	0.37783467207596577	[326]	[298,439,314,440]	5	hSpCas9	negative selection	7811378
84185099	84185122	1	+	27260156	PANC0327	viability	GGATAATTCTAATTTATACATGG	PRKACB	ENSG00000142875	-0.4755863185095741	[148]	[117,76,118,70]	-6	hSpCas9	negative selection	7811379
84078316	84078339	1	+	27260156	NCIH2009	viability	CGCCCCAGACATGGGGAACGCGG	PRKACB	ENSG00000142875	0.045085777279965544	[156]	[201,157,314]	0	hSpCas9	negative selection	7868370
84185136	84185159	1	-	27260156	NCIH2009	viability	TGTGAAAACATTTCACCCCCAGG	PRKACB	ENSG00000142875	0.018740938707123345	[939]	[1393,1373,1232]	0	hSpCas9	negative selection	7868371
84182236	84182259	1	+	27260156	NCIH2009	viability	ACCCTTGGAACAGGTTCATTTGG	PRKACB	ENSG00000142875	0.515364996717774	[805]	[2040,1243,1632]	7	hSpCas9	negative selection	7868372
84078340	84078363	1	+	27260156	NCIH2009	viability	GACCGCCAAGAAAGGCAGCGAGG	PRKACB	ENSG00000142875	-0.005206508020530964	[374]	[581,692,298]	0	hSpCas9	negative selection	7932628
84182303	84182326	1	-	27260156	NCIH2009	viability	CTGCTTATCTAAGATCTTCATGG	PRKACB	ENSG00000142875	0.4664350704812292	[326]	[524,613,732]	6	hSpCas9	negative selection	7932629
84185099	84185122	1	+	27260156	NCIH2009	viability	GGATAATTCTAATTTATACATGG	PRKACB	ENSG00000142875	0.05421909259331659	[148]	[261,223,170]	0	hSpCas9	negative selection	7932630
84078316	84078339	1	+	27260156	NCIH1373	viability	CGCCCCAGACATGGGGAACGCGG	PRKACB	ENSG00000142875	0.419060168146246	[156]	[139,170,206,111]	4	hSpCas9	negative selection	7989621
84185136	84185159	1	-	27260156	NCIH1373	viability	TGTGAAAACATTTCACCCCCAGG	PRKACB	ENSG00000142875	0.1786208592585019	[939]	[1428,866,1369,305]	1	hSpCas9	negative selection	7989622
84182236	84182259	1	+	27260156	NCIH1373	viability	ACCCTTGGAACAGGTTCATTTGG	PRKACB	ENSG00000142875	0.6218681059235596	[805]	[1510,1139,1863,276]	6	hSpCas9	negative selection	7989623
84078340	84078363	1	+	27260156	NCIH1373	viability	GACCGCCAAGAAAGGCAGCGAGG	PRKACB	ENSG00000142875	0.050826658673999436	[374]	[584,351,306,140]	0	hSpCas9	negative selection	8053879
84182303	84182326	1	-	27260156	NCIH1373	viability	CTGCTTATCTAAGATCTTCATGG	PRKACB	ENSG00000142875	0.3041677655899772	[326]	[471,409,395,142]	3	hSpCas9	negative selection	8053880
84185099	84185122	1	+	27260156	NCIH1373	viability	GGATAATTCTAATTTATACATGG	PRKACB	ENSG00000142875	0.0737125139416519	[148]	[255,238,99,28]	0	hSpCas9	negative selection	8053881
84078316	84078339	1	+	27260156	PATU8902	viability	CGCCCCAGACATGGGGAACGCGG	PRKACB	ENSG00000142875	-0.47654062991760693	[156]	[81,151,29,429]	-5	hSpCas9	negative selection	8110872
84185136	84185159	1	-	27260156	PATU8902	viability	TGTGAAAACATTTCACCCCCAGG	PRKACB	ENSG00000142875	0.24590276226882346	[939]	[1532,1666,1058,2136]	2	hSpCas9	negative selection	8110873
84182236	84182259	1	+	27260156	PATU8902	viability	ACCCTTGGAACAGGTTCATTTGG	PRKACB	ENSG00000142875	0.13354233953000638	[805]	[1058,1099,1109,1740]	1	hSpCas9	negative selection	8110874
84078340	84078363	1	+	27260156	PATU8902	viability	GACCGCCAAGAAAGGCAGCGAGG	PRKACB	ENSG00000142875	0.2153764697614996	[374]	[575,928,396,569]	2	hSpCas9	negative selection	8175130
84182303	84182326	1	-	27260156	PATU8902	viability	CTGCTTATCTAAGATCTTCATGG	PRKACB	ENSG00000142875	0.781229083234169	[326]	[752,819,638,972]	8	hSpCas9	negative selection	8175131
84185099	84185122	1	+	27260156	PATU8902	viability	GGATAATTCTAATTTATACATGG	PRKACB	ENSG00000142875	-0.1169193157797539	[148]	[167,145,112,379]	-1	hSpCas9	negative selection	8175132
84078316	84078339	1	+	27260156	PANC1	viability	CGCCCCAGACATGGGGAACGCGG	PRKACB	ENSG00000142875	0.0274367412061578	[156]	[104,212,124,122]	0	hSpCas9	negative selection	8232123
84185136	84185159	1	-	27260156	PANC1	viability	TGTGAAAACATTTCACCCCCAGG	PRKACB	ENSG00000142875	0.37656069426321537	[939]	[1056,1372,1116,745]	6	hSpCas9	negative selection	8232124
84182236	84182259	1	+	27260156	PANC1	viability	ACCCTTGGAACAGGTTCATTTGG	PRKACB	ENSG00000142875	0.15916785723809257	[805]	[711,986,833,617]	2	hSpCas9	negative selection	8232125
84078340	84078363	1	+	27260156	PANC1	viability	GACCGCCAAGAAAGGCAGCGAGG	PRKACB	ENSG00000142875	0.06411402791810555	[374]	[556,345,226,225]	1	hSpCas9	negative selection	8296381
84182303	84182326	1	-	27260156	PANC1	viability	CTGCTTATCTAAGATCTTCATGG	PRKACB	ENSG00000142875	0.5126514262147959	[326]	[361,575,398,310]	8	hSpCas9	negative selection	8296382
84185099	84185122	1	+	27260156	PANC1	viability	GGATAATTCTAATTTATACATGG	PRKACB	ENSG00000142875	0.04253087969075198	[148]	[158,163,124,89]	0	hSpCas9	negative selection	8296383
84078316	84078339	1	+	27260156	PANC0813	viability	CGCCCCAGACATGGGGAACGCGG	PRKACB	ENSG00000142875	-0.2291014073484854	[156]	[217,48,192,173]	-4	hSpCas9	negative selection	8353374
84185136	84185159	1	-	27260156	PANC0813	viability	TGTGAAAACATTTCACCCCCAGG	PRKACB	ENSG00000142875	0.26562004507091297	[939]	[1246,1776,1259,1031]	4	hSpCas9	negative selection	8353375
84182236	84182259	1	+	27260156	PANC0813	viability	ACCCTTGGAACAGGTTCATTTGG	PRKACB	ENSG00000142875	0.2859047042122991	[805]	[1110,1269,994,1229]	4	hSpCas9	negative selection	8353376
84078340	84078363	1	+	27260156	PANC0813	viability	GACCGCCAAGAAAGGCAGCGAGG	PRKACB	ENSG00000142875	-0.06728101920785468	[374]	[439,317,568,359]	-1	hSpCas9	negative selection	8417632
84182303	84182326	1	-	27260156	PANC0813	viability	CTGCTTATCTAAGATCTTCATGG	PRKACB	ENSG00000142875	0.33167188588640806	[326]	[674,373,396,502]	5	hSpCas9	negative selection	8417633
84185099	84185122	1	+	27260156	PANC0813	viability	GGATAATTCTAATTTATACATGG	PRKACB	ENSG00000142875	0.032054889224320204	[148]	[139,154,285,133]	0	hSpCas9	negative selection	8417634
84078316	84078339	1	+	27260156	RDES	viability	CGCCCCAGACATGGGGAACGCGG	PRKACB	ENSG00000142875	0.44418797742195637	[156]	[138,300,201,368]	7	hSpCas9	negative selection	8474625
84185136	84185159	1	-	27260156	RDES	viability	TGTGAAAACATTTCACCCCCAGG	PRKACB	ENSG00000142875	0.3404426218638763	[939]	[1229,1306,1501,1443]	5	hSpCas9	negative selection	8474626
84182236	84182259	1	+	27260156	RDES	viability	ACCCTTGGAACAGGTTCATTTGG	PRKACB	ENSG00000142875	0.42713172830004886	[805]	[1037,1140,1377,1486]	6	hSpCas9	negative selection	8474627
84078340	84078363	1	+	27260156	RDES	viability	GACCGCCAAGAAAGGCAGCGAGG	PRKACB	ENSG00000142875	-0.04152775983526341	[374]	[297,353,517,550]	0	hSpCas9	negative selection	8538883
84182303	84182326	1	-	27260156	RDES	viability	CTGCTTATCTAAGATCTTCATGG	PRKACB	ENSG00000142875	0.4242045105099804	[326]	[357,525,569,595]	6	hSpCas9	negative selection	8538884
84185099	84185122	1	+	27260156	RDES	viability	GGATAATTCTAATTTATACATGG	PRKACB	ENSG00000142875	0.4017439297301084	[148]	[159,226,245,290]	6	hSpCas9	negative selection	8538885
84078316	84078339	1	+	27260156	PC3	viability	CGCCCCAGACATGGGGAACGCGG	PRKACB	ENSG00000142875	-0.23956735455690636	[156]	[81,107,327,97]	-5	hSpCas9	negative selection	8595876
84185136	84185159	1	-	27260156	PC3	viability	TGTGAAAACATTTCACCCCCAGG	PRKACB	ENSG00000142875	0.319399682577469	[939]	[778,1013,1998,1272]	6	hSpCas9	negative selection	8595877
84182236	84182259	1	+	27260156	PC3	viability	ACCCTTGGAACAGGTTCATTTGG	PRKACB	ENSG00000142875	0.22014864753207364	[805]	[716,1088,1204,806]	5	hSpCas9	negative selection	8595878
84078340	84078363	1	+	27260156	PC3	viability	GACCGCCAAGAAAGGCAGCGAGG	PRKACB	ENSG00000142875	-0.38680791509898294	[374]	[205,247,517,266]	-7	hSpCas9	negative selection	8660134
84182303	84182326	1	-	27260156	PC3	viability	CTGCTTATCTAAGATCTTCATGG	PRKACB	ENSG00000142875	0.35098529432488446	[326]	[239,418,1025,247]	7	hSpCas9	negative selection	8660135
84185099	84185122	1	+	27260156	PC3	viability	GGATAATTCTAATTTATACATGG	PRKACB	ENSG00000142875	-0.13892914592219463	[148]	[81,134,256,122]	-3	hSpCas9	negative selection	8660136
84078316	84078339	1	+	27260156	PATU8988T	viability	CGCCCCAGACATGGGGAACGCGG	PRKACB	ENSG00000142875	0.454411376924571	[156]	[194,130,143,367]	7	hSpCas9	negative selection	8717127
84185136	84185159	1	-	27260156	PATU8988T	viability	TGTGAAAACATTTCACCCCCAGG	PRKACB	ENSG00000142875	0.4395184502807503	[939]	[1062,1068,1391,1398]	7	hSpCas9	negative selection	8717128
84182236	84182259	1	+	27260156	PATU8988T	viability	ACCCTTGGAACAGGTTCATTTGG	PRKACB	ENSG00000142875	0.41416736727040027	[805]	[1137,856,1171,958]	7	hSpCas9	negative selection	8717129
84078340	84078363	1	+	27260156	PATU8988T	viability	GACCGCCAAGAAAGGCAGCGAGG	PRKACB	ENSG00000142875	0.1649423793979583	[374]	[596,458,318,242]	3	hSpCas9	negative selection	8781385
84182303	84182326	1	-	27260156	PATU8988T	viability	CTGCTTATCTAAGATCTTCATGG	PRKACB	ENSG00000142875	-0.31771604876200754	[326]	[185,265,322,237]	-5	hSpCas9	negative selection	8781386
84185099	84185122	1	+	27260156	PATU8988T	viability	GGATAATTCTAATTTATACATGG	PRKACB	ENSG00000142875	0.5353372682242974	[148]	[151,161,314,198]	8	hSpCas9	negative selection	8781387
84078316	84078339	1	+	27260156	T47D	viability	CGCCCCAGACATGGGGAACGCGG	PRKACB	ENSG00000142875	0.17594249436364096	[156]	[224,202,233,162]	4	hSpCas9	negative selection	8838378
84185136	84185159	1	-	27260156	T47D	viability	TGTGAAAACATTTCACCCCCAGG	PRKACB	ENSG00000142875	0.4006119800493724	[939]	[1417,1375,1489,1504]	8	hSpCas9	negative selection	8838379
84182236	84182259	1	+	27260156	T47D	viability	ACCCTTGGAACAGGTTCATTTGG	PRKACB	ENSG00000142875	0.3595815691185573	[805]	[1223,1147,1164,1289]	7	hSpCas9	negative selection	8838380
84078340	84078363	1	+	27260156	T47D	viability	GACCGCCAAGAAAGGCAGCGAGG	PRKACB	ENSG00000142875	0.15891930592351616	[374]	[563,483,468,432]	3	hSpCas9	negative selection	8902636
84182303	84182326	1	-	27260156	T47D	viability	CTGCTTATCTAAGATCTTCATGG	PRKACB	ENSG00000142875	0.42021004057123973	[326]	[552,471,514,501]	8	hSpCas9	negative selection	8902637
84185099	84185122	1	+	27260156	T47D	viability	GGATAATTCTAATTTATACATGG	PRKACB	ENSG00000142875	0.48464115784761774	[148]	[220,204,338,206]	8	hSpCas9	negative selection	8902638
84078316	84078339	1	+	27260156	SU8686	viability	CGCCCCAGACATGGGGAACGCGG	PRKACB	ENSG00000142875	-0.7126355063254857	[156]	[123,65,104,82]	-8	hSpCas9	negative selection	8959629
84185136	84185159	1	-	27260156	SU8686	viability	TGTGAAAACATTTCACCCCCAGG	PRKACB	ENSG00000142875	0.42502383256680387	[939]	[1165,1041,1201,1692]	7	hSpCas9	negative selection	8959630
84182236	84182259	1	+	27260156	SU8686	viability	ACCCTTGGAACAGGTTCATTTGG	PRKACB	ENSG00000142875	0.43765776471564455	[805]	[1041,1001,1037,1285]	7	hSpCas9	negative selection	8959631
84078340	84078363	1	+	27260156	SU8686	viability	GACCGCCAAGAAAGGCAGCGAGG	PRKACB	ENSG00000142875	-0.29987777287784334	[374]	[280,208,300,453]	-5	hSpCas9	negative selection	9023887
84182303	84182326	1	-	27260156	SU8686	viability	CTGCTTATCTAAGATCTTCATGG	PRKACB	ENSG00000142875	0.12311361027372253	[326]	[394,315,366,327]	2	hSpCas9	negative selection	9023888
84185099	84185122	1	+	27260156	SU8686	viability	GGATAATTCTAATTTATACATGG	PRKACB	ENSG00000142875	0.42856851682180186	[148]	[188,207,170,229]	7	hSpCas9	negative selection	9023889
84078316	84078339	1	+	27260156	SKES1	viability	CGCCCCAGACATGGGGAACGCGG	PRKACB	ENSG00000142875	-0.2344606471162436	[156]	[128,177,164,70]	-5	hSpCas9	negative selection	9080880
84185136	84185159	1	-	27260156	SKES1	viability	TGTGAAAACATTTCACCCCCAGG	PRKACB	ENSG00000142875	0.3738568033673362	[939]	[1349,1419,1088,1052]	7	hSpCas9	negative selection	9080881
84182236	84182259	1	+	27260156	SKES1	viability	ACCCTTGGAACAGGTTCATTTGG	PRKACB	ENSG00000142875	0.20326542138772463	[805]	[994,1117,817,809]	4	hSpCas9	negative selection	9080882
84078340	84078363	1	+	27260156	SKES1	viability	GACCGCCAAGAAAGGCAGCGAGG	PRKACB	ENSG00000142875	-0.22464502083867965	[374]	[338,344,296,303]	-5	hSpCas9	negative selection	9145138
84182303	84182326	1	-	27260156	SKES1	viability	CTGCTTATCTAAGATCTTCATGG	PRKACB	ENSG00000142875	0.191368928296565	[326]	[376,357,369,378]	4	hSpCas9	negative selection	9145139
84185099	84185122	1	+	27260156	SKES1	viability	GGATAATTCTAATTTATACATGG	PRKACB	ENSG00000142875	-0.03292295643011478	[148]	[136,165,131,145]	0	hSpCas9	negative selection	9145140
84078316	84078339	1	+	27260156	TOV112D	viability	CGCCCCAGACATGGGGAACGCGG	PRKACB	ENSG00000142875	-0.1608241325086157	[156]	[152,178,104,135]	-3	hSpCas9	negative selection	9202131
84185136	84185159	1	-	27260156	TOV112D	viability	TGTGAAAACATTTCACCCCCAGG	PRKACB	ENSG00000142875	0.5879093133514641	[939]	[1377,2023,1252,1156]	9	hSpCas9	negative selection	9202132
84182236	84182259	1	+	27260156	TOV112D	viability	ACCCTTGGAACAGGTTCATTTGG	PRKACB	ENSG00000142875	0.3887567715993785	[805]	[882,1690,762,1030]	7	hSpCas9	negative selection	9202133
84078340	84078363	1	+	27260156	TOV112D	viability	GACCGCCAAGAAAGGCAGCGAGG	PRKACB	ENSG00000142875	0.02435115041442526	[374]	[314,557,456,238]	0	hSpCas9	negative selection	9266389
84182303	84182326	1	-	27260156	TOV112D	viability	CTGCTTATCTAAGATCTTCATGG	PRKACB	ENSG00000142875	0.33191313005542045	[326]	[521,444,266,430]	6	hSpCas9	negative selection	9266390
84185099	84185122	1	+	27260156	TOV112D	viability	GGATAATTCTAATTTATACATGG	PRKACB	ENSG00000142875	0.2469473081874305	[148]	[143,264,179,138]	5	hSpCas9	negative selection	9266391
84078316	84078339	1	+	27260156	TC71	viability	CGCCCCAGACATGGGGAACGCGG	PRKACB	ENSG00000142875	0.17242505457514223	[156]	[203,163,169,222]	4	hSpCas9	negative selection	9323382
84185136	84185159	1	-	27260156	TC71	viability	TGTGAAAACATTTCACCCCCAGG	PRKACB	ENSG00000142875	0.5015264283902281	[939]	[1479,1487,1277,1465]	9	hSpCas9	negative selection	9323383
84182236	84182259	1	+	27260156	TC71	viability	ACCCTTGGAACAGGTTCATTTGG	PRKACB	ENSG00000142875	0.16691289252689567	[805]	[957,994,881,1052]	4	hSpCas9	negative selection	9323384
84078340	84078363	1	+	27260156	TC71	viability	GACCGCCAAGAAAGGCAGCGAGG	PRKACB	ENSG00000142875	-0.21908487263502585	[374]	[434,265,280,402]	-5	hSpCas9	negative selection	9387640
84182303	84182326	1	-	27260156	TC71	viability	CTGCTTATCTAAGATCTTCATGG	PRKACB	ENSG00000142875	0.24530439705998258	[326]	[335,353,445,533]	6	hSpCas9	negative selection	9387641
84185099	84185122	1	+	27260156	TC71	viability	GGATAATTCTAATTTATACATGG	PRKACB	ENSG00000142875	0.30599924572308335	[148]	[221,190,167,209]	7	hSpCas9	negative selection	9387642
84078316	84078339	1	+	27260156	TC32	viability	CGCCCCAGACATGGGGAACGCGG	PRKACB	ENSG00000142875	0.25694241334768075	[156]	[170,124,201,223]	4	hSpCas9	negative selection	9444633
84185136	84185159	1	-	27260156	TC32	viability	TGTGAAAACATTTCACCCCCAGG	PRKACB	ENSG00000142875	0.40872591979850625	[939]	[1170,862,1719,1072]	7	hSpCas9	negative selection	9444634
84182236	84182259	1	+	27260156	TC32	viability	ACCCTTGGAACAGGTTCATTTGG	PRKACB	ENSG00000142875	0.24635665169854915	[805]	[798,628,1128,1153]	4	hSpCas9	negative selection	9444635
84078340	84078363	1	+	27260156	TC32	viability	GACCGCCAAGAAAGGCAGCGAGG	PRKACB	ENSG00000142875	-0.022754215465993488	[374]	[319,196,461,476]	0	hSpCas9	negative selection	9508891
84182303	84182326	1	-	27260156	TC32	viability	CTGCTTATCTAAGATCTTCATGG	PRKACB	ENSG00000142875	0.018923887025636632	[326]	[294,214,353,414]	0	hSpCas9	negative selection	9508892
84185099	84185122	1	+	27260156	TC32	viability	GGATAATTCTAATTTATACATGG	PRKACB	ENSG00000142875	0.03231013612557332	[148]	[166,129,126,137]	0	hSpCas9	negative selection	9508893
84078332	84078355	1	+	27869803	HPAFII	viability after 27 days	AACGCGGCGACCGCCAAGAAAGG	PRKACB	ENSG00000142875	-0.3159590069220814	[428]	[190,172,NaN]	-2	hSpCas9	negative selection	9535719
84144380	84144403	1	-	27869803	HPAFII	viability after 27 days	CCTGTATACTGGTTACAAGGTGG	PRKACB	ENSG00000142875	-0.6176983448729707	[501]	[87,241,NaN]	-4	hSpCas9	negative selection	9535720
84184108	84184131	1	-	27869803	HPAFII	viability after 27 days	AAGCATACTCCAGTCGAACAAGG	PRKACB	ENSG00000142875	0.8099217420226401	[360]	[179,459,NaN]	6	hSpCas9	negative selection	9535721
84214167	84214190	1	-	27869803	HPAFII	viability after 27 days	CCTTGAGATCTGAACTGAAGTGG	PRKACB	ENSG00000142875	0.35773085565900903	[340]	[400,86,NaN]	3	hSpCas9	negative selection	9535722
84078332	84078355	1	+	27869803	HPAFII	viability after 15 days	AACGCGGCGACCGCCAAGAAAGG	PRKACB	ENSG00000142875	-0.08369044780722423	[428]	[513,385,NaN]	-1	hSpCas9	negative selection	9618168
84144380	84144403	1	-	27869803	HPAFII	viability after 15 days	CCTGTATACTGGTTACAAGGTGG	PRKACB	ENSG00000142875	-0.9933499851735778	[501]	[307,247,NaN]	-7	hSpCas9	negative selection	9618169
84184108	84184131	1	-	27869803	HPAFII	viability after 15 days	AAGCATACTCCAGTCGAACAAGG	PRKACB	ENSG00000142875	0.008435308604395897	[360]	[417,372,NaN]	0	hSpCas9	negative selection	9618170
84214167	84214190	1	-	27869803	HPAFII	viability after 15 days	CCTTGAGATCTGAACTGAAGTGG	PRKACB	ENSG00000142875	0.1456541368353777	[340]	[738,197,NaN]	1	hSpCas9	negative selection	9618171
84078332	84078355	1	+	27869803	ASPC1	viability after 36 days	AACGCGGCGACCGCCAAGAAAGG	PRKACB	ENSG00000142875	-0.07825056616229559	[892]	[394,326,196]	-1	hSpCas9	negative selection	9700617
84144380	84144403	1	-	27869803	ASPC1	viability after 36 days	CCTGTATACTGGTTACAAGGTGG	PRKACB	ENSG00000142875	0.27198855708411696	[933]	[244,395,491]	2	hSpCas9	negative selection	9700618
84184108	84184131	1	-	27869803	ASPC1	viability after 36 days	AAGCATACTCCAGTCGAACAAGG	PRKACB	ENSG00000142875	0.06345261801637925	[849]	[471,240,247]	0	hSpCas9	negative selection	9700619
84214167	84214190	1	-	27869803	ASPC1	viability after 36 days	CCTTGAGATCTGAACTGAAGTGG	PRKACB	ENSG00000142875	0.48862160745092376	[903]	[589,371,390]	5	hSpCas9	negative selection	9700620
84078332	84078355	1	+	27869803	PATU8988S	viability after 35 days	AACGCGGCGACCGCCAAGAAAGG	PRKACB	ENSG00000142875	0.6332645059502288	[805]	[504,501,NaN]	7	hSpCas9	negative selection	9783066
84144380	84144403	1	-	27869803	PATU8988S	viability after 35 days	CCTGTATACTGGTTACAAGGTGG	PRKACB	ENSG00000142875	0.007691406935750322	[1013]	[441,378,NaN]	0	hSpCas9	negative selection	9783067
84184108	84184131	1	-	27869803	PATU8988S	viability after 35 days	AAGCATACTCCAGTCGAACAAGG	PRKACB	ENSG00000142875	0.7767432951159348	[792]	[626,466,NaN]	8	hSpCas9	negative selection	9783068
84214167	84214190	1	-	27869803	PATU8988S	viability after 35 days	CCTTGAGATCTGAACTGAAGTGG	PRKACB	ENSG00000142875	-0.17384296893665685	[741]	[227,301,NaN]	-2	hSpCas9	negative selection	9783069
84078332	84078355	1	+	27869803	PATU8988S	viability after 31 days	AACGCGGCGACCGCCAAGAAAGG	PRKACB	ENSG00000142875	0.4850524696588764	[805]	[378,539,NaN]	6	hSpCas9	negative selection	9865515
84144380	84144403	1	-	27869803	PATU8988S	viability after 31 days	CCTGTATACTGGTTACAAGGTGG	PRKACB	ENSG00000142875	-0.08788435513144333	[1013]	[335,436,NaN]	-1	hSpCas9	negative selection	9865516
84184108	84184131	1	-	27869803	PATU8988S	viability after 31 days	AAGCATACTCCAGTCGAACAAGG	PRKACB	ENSG00000142875	0.35250527371275386	[792]	[408,396,NaN]	4	hSpCas9	negative selection	9865517
84214167	84214190	1	-	27869803	PATU8988S	viability after 31 days	CCTTGAGATCTGAACTGAAGTGG	PRKACB	ENSG00000142875	-0.2733992200641734	[741]	[202,297,NaN]	-3	hSpCas9	negative selection	9865518
84078332	84078355	1	+	27869803	HPAFII	viability after 35 days	AACGCGGCGACCGCCAAGAAAGG	PRKACB	ENSG00000142875	0.13833624041712989	[428]	[310,157,NaN]	0	hSpCas9	negative selection	9947964
84144380	84144403	1	-	27869803	HPAFII	viability after 35 days	CCTGTATACTGGTTACAAGGTGG	PRKACB	ENSG00000142875	-0.6108474278536671	[501]	[45,301,NaN]	-4	hSpCas9	negative selection	9947965
84184108	84184131	1	-	27869803	HPAFII	viability after 35 days	AAGCATACTCCAGTCGAACAAGG	PRKACB	ENSG00000142875	0.7847715888954181	[360]	[137,513,NaN]	5	hSpCas9	negative selection	9947966
84214167	84214190	1	-	27869803	HPAFII	viability after 35 days	CCTTGAGATCTGAACTGAAGTGG	PRKACB	ENSG00000142875	0.43232857656489915	[340]	[366,81,NaN]	2	hSpCas9	negative selection	9947967
84078332	84078355	1	+	27869803	HPAFII	viability after 31 days	AACGCGGCGACCGCCAAGAAAGG	PRKACB	ENSG00000142875	-0.17617257299561329	[428]	[281,137,NaN]	-1	hSpCas9	negative selection	10030413
84144380	84144403	1	-	27869803	HPAFII	viability after 31 days	CCTGTATACTGGTTACAAGGTGG	PRKACB	ENSG00000142875	-0.34938411961831817	[501]	[145,302,NaN]	-2	hSpCas9	negative selection	10030414
84184108	84184131	1	-	27869803	HPAFII	viability after 31 days	AAGCATACTCCAGTCGAACAAGG	PRKACB	ENSG00000142875	0.7348852147500624	[360]	[128,563,NaN]	5	hSpCas9	negative selection	10030415
84214167	84214190	1	-	27869803	HPAFII	viability after 31 days	CCTTGAGATCTGAACTGAAGTGG	PRKACB	ENSG00000142875	0.7822820412099394	[340]	[454,191,NaN]	6	hSpCas9	negative selection	10030416
84202679	84202702	1	+	28162770	P31FUJ	viability	TCAGGGCTACAATAAGGCAGTGG	PRKACB	ENSG00000142875	0.6925589946928656	[118]	[225]	7	hSpCas9	negative selection	10216960
84202695	84202718	1	+	28162770	P31FUJ	viability	GCAGTGGATTGGTGGGCATTAGG	PRKACB	ENSG00000142875	0.3592596886901138	[472]	[712]	4	hSpCas9	negative selection	10216961
84196667	84196690	1	-	28162770	P31FUJ	viability	AGATGAGGTCTAGTGAATGGAGG	PRKACB	ENSG00000142875	0.7914453418322989	[58]	[119]	8	hSpCas9	negative selection	10216962
84196622	84196645	1	-	28162770	P31FUJ	viability	GAGCTGCATAGAACCGTGCATGG	PRKACB	ENSG00000142875	1.0005115032994156	[187]	[441]	9	hSpCas9	negative selection	10216963
84179217	84179240	1	+	28162770	P31FUJ	viability	AAAATGGGAGAATCCAACTCAGG	PRKACB	ENSG00000142875	0.41276706101092975	[100]	[157]	4	hSpCas9	negative selection	10216964
84185120	84185143	1	+	28162770	P31FUJ	viability	GGTTATGGAATATGTCCCTGGGG	PRKACB	ENSG00000142875	-0.016723557010132832	[228]	[265]	0	hSpCas9	negative selection	10216965
84202750	84202773	1	-	28162770	P31FUJ	viability	TGGTTGGTCTGCAAAGAATGGGG	PRKACB	ENSG00000142875	0.8051456709137041	[468]	[962]	8	hSpCas9	negative selection	10216966
84182285	84182308	1	-	28162770	P31FUJ	viability	CATGGCATAATACTGTTCAGTGG	PRKACB	ENSG00000142875	0.580429283979895	[69]	[122]	6	hSpCas9	negative selection	10216967
84197741	84197764	1	+	28162770	P31FUJ	viability	GGGTTTGCCAAAAGAGTTAAAGG	PRKACB	ENSG00000142875	0.12663668537247774	[409]	[525]	1	hSpCas9	negative selection	10216968
84196721	84196744	1	+	28162770	P31FUJ	viability	TGACCATCAAGGCTATATCCAGG	PRKACB	ENSG00000142875	0.40724082149942475	[590]	[920]	4	hSpCas9	negative selection	10216969
84202679	84202702	1	+	28162770	TF1	viability	TCAGGGCTACAATAAGGCAGTGG	PRKACB	ENSG00000142875	NaN	[NaN]	[50]	1	hSpCas9	negative selection	10386326
84202695	84202718	1	+	28162770	TF1	viability	GCAGTGGATTGGTGGGCATTAGG	PRKACB	ENSG00000142875	NaN	[NaN]	[722]	1	hSpCas9	negative selection	10386327
84196667	84196690	1	-	28162770	TF1	viability	AGATGAGGTCTAGTGAATGGAGG	PRKACB	ENSG00000142875	NaN	[NaN]	[233]	1	hSpCas9	negative selection	10386328
84196622	84196645	1	-	28162770	TF1	viability	GAGCTGCATAGAACCGTGCATGG	PRKACB	ENSG00000142875	NaN	[NaN]	[284]	1	hSpCas9	negative selection	10386329
84179217	84179240	1	+	28162770	TF1	viability	AAAATGGGAGAATCCAACTCAGG	PRKACB	ENSG00000142875	NaN	[NaN]	[97]	1	hSpCas9	negative selection	10386330
84185120	84185143	1	+	28162770	TF1	viability	GGTTATGGAATATGTCCCTGGGG	PRKACB	ENSG00000142875	NaN	[NaN]	[205]	1	hSpCas9	negative selection	10386331
84202750	84202773	1	-	28162770	TF1	viability	TGGTTGGTCTGCAAAGAATGGGG	PRKACB	ENSG00000142875	NaN	[NaN]	[584]	1	hSpCas9	negative selection	10386332
84182285	84182308	1	-	28162770	TF1	viability	CATGGCATAATACTGTTCAGTGG	PRKACB	ENSG00000142875	NaN	[NaN]	[148]	1	hSpCas9	negative selection	10386333
84197741	84197764	1	+	28162770	TF1	viability	GGGTTTGCCAAAAGAGTTAAAGG	PRKACB	ENSG00000142875	NaN	[NaN]	[457]	1	hSpCas9	negative selection	10386334
84196721	84196744	1	+	28162770	TF1	viability	TGACCATCAAGGCTATATCCAGG	PRKACB	ENSG00000142875	NaN	[NaN]	[430]	1	hSpCas9	negative selection	10386335
84202679	84202702	1	+	28162770	SKM1	viability	TCAGGGCTACAATAAGGCAGTGG	PRKACB	ENSG00000142875	0.47755858383690253	[25]	[63]	4	hSpCas9	negative selection	10555692
84202695	84202718	1	+	28162770	SKM1	viability	GCAGTGGATTGGTGGGCATTAGG	PRKACB	ENSG00000142875	0.5873892381156963	[95]	[254]	5	hSpCas9	negative selection	10555693
84196667	84196690	1	-	28162770	SKM1	viability	AGATGAGGTCTAGTGAATGGAGG	PRKACB	ENSG00000142875	0.04049477822805958	[21]	[39]	0	hSpCas9	negative selection	10555694
84196622	84196645	1	-	28162770	SKM1	viability	GAGCTGCATAGAACCGTGCATGG	PRKACB	ENSG00000142875	0.44451327654675005	[68]	[165]	4	hSpCas9	negative selection	10555695
84179217	84179240	1	+	28162770	SKM1	viability	AAAATGGGAGAATCCAACTCAGG	PRKACB	ENSG00000142875	0.6336777857541843	[34]	[95]	6	hSpCas9	negative selection	10555696
84185120	84185143	1	+	28162770	SKM1	viability	GGTTATGGAATATGTCCCTGGGG	PRKACB	ENSG00000142875	0.7154324326165646	[71]	[208]	7	hSpCas9	negative selection	10555697
84202750	84202773	1	-	28162770	SKM1	viability	TGGTTGGTCTGCAAAGAATGGGG	PRKACB	ENSG00000142875	1.0123202716358681	[105]	[377]	8	hSpCas9	negative selection	10555698
84182285	84182308	1	-	28162770	SKM1	viability	CATGGCATAATACTGTTCAGTGG	PRKACB	ENSG00000142875	0.6436618743268064	[20]	[57]	6	hSpCas9	negative selection	10555699
84197741	84197764	1	+	28162770	SKM1	viability	GGGTTTGCCAAAAGAGTTAAAGG	PRKACB	ENSG00000142875	0.7743655659714	[83]	[253]	7	hSpCas9	negative selection	10555700
84196721	84196744	1	+	28162770	SKM1	viability	TGACCATCAAGGCTATATCCAGG	PRKACB	ENSG00000142875	0.06396305873196506	[124]	[230]	0	hSpCas9	negative selection	10555701
84202679	84202702	1	+	28162770	SKM1	viability	TCAGGGCTACAATAAGGCAGTGG	PRKACB	ENSG00000142875	0.47755858383690253	[25]	[63]	4	hSpCas9	negative selection	10725058
84202695	84202718	1	+	28162770	SKM1	viability	GCAGTGGATTGGTGGGCATTAGG	PRKACB	ENSG00000142875	0.5873892381156963	[95]	[254]	5	hSpCas9	negative selection	10725059
84196667	84196690	1	-	28162770	SKM1	viability	AGATGAGGTCTAGTGAATGGAGG	PRKACB	ENSG00000142875	0.04049477822805958	[21]	[39]	0	hSpCas9	negative selection	10725060
84196622	84196645	1	-	28162770	SKM1	viability	GAGCTGCATAGAACCGTGCATGG	PRKACB	ENSG00000142875	0.44451327654675005	[68]	[165]	4	hSpCas9	negative selection	10725061
84179217	84179240	1	+	28162770	SKM1	viability	AAAATGGGAGAATCCAACTCAGG	PRKACB	ENSG00000142875	0.6336777857541843	[34]	[95]	6	hSpCas9	negative selection	10725062
84185120	84185143	1	+	28162770	SKM1	viability	GGTTATGGAATATGTCCCTGGGG	PRKACB	ENSG00000142875	0.7154324326165646	[71]	[208]	7	hSpCas9	negative selection	10725063
84202750	84202773	1	-	28162770	SKM1	viability	TGGTTGGTCTGCAAAGAATGGGG	PRKACB	ENSG00000142875	1.0123202716358681	[105]	[377]	8	hSpCas9	negative selection	10725064
84182285	84182308	1	-	28162770	SKM1	viability	CATGGCATAATACTGTTCAGTGG	PRKACB	ENSG00000142875	0.6436618743268064	[20]	[57]	6	hSpCas9	negative selection	10725065
84197741	84197764	1	+	28162770	SKM1	viability	GGGTTTGCCAAAAGAGTTAAAGG	PRKACB	ENSG00000142875	0.7743655659714	[83]	[253]	7	hSpCas9	negative selection	10725066
84196721	84196744	1	+	28162770	SKM1	viability	TGACCATCAAGGCTATATCCAGG	PRKACB	ENSG00000142875	0.06396305873196506	[124]	[230]	0	hSpCas9	negative selection	10725067
84202679	84202702	1	+	28162770	PL21	viability	TCAGGGCTACAATAAGGCAGTGG	PRKACB	ENSG00000142875	-0.8229439986237209	[125]	[30]	-5	hSpCas9	negative selection	10894424
84202695	84202718	1	+	28162770	PL21	viability	GCAGTGGATTGGTGGGCATTAGG	PRKACB	ENSG00000142875	0.4000090191996287	[248]	[142]	3	hSpCas9	negative selection	10894425
84196667	84196690	1	-	28162770	PL21	viability	AGATGAGGTCTAGTGAATGGAGG	PRKACB	ENSG00000142875	-0.717398225318707	[67]	[17]	-5	hSpCas9	negative selection	10894426
84196622	84196645	1	-	28162770	PL21	viability	GAGCTGCATAGAACCGTGCATGG	PRKACB	ENSG00000142875	0.4932704450692477	[252]	[154]	4	hSpCas9	negative selection	10894427
84179217	84179240	1	+	28162770	PL21	viability	AAAATGGGAGAATCCAACTCAGG	PRKACB	ENSG00000142875	0.6356412163278794	[104]	[70]	5	hSpCas9	negative selection	10894428
84185120	84185143	1	+	28162770	PL21	viability	GGTTATGGAATATGTCCCTGGGG	PRKACB	ENSG00000142875	0.3685371461850385	[209]	[117]	3	hSpCas9	negative selection	10894429
84202750	84202773	1	-	28162770	PL21	viability	TGGTTGGTCTGCAAAGAATGGGG	PRKACB	ENSG00000142875	0.9232330340739687	[417]	[344]	7	hSpCas9	negative selection	10894430
84182285	84182308	1	-	28162770	PL21	viability	CATGGCATAATACTGTTCAGTGG	PRKACB	ENSG00000142875	-0.3234223415676927	[45]	[15]	-2	hSpCas9	negative selection	10894431
84197741	84197764	1	+	28162770	PL21	viability	GGGTTTGCCAAAAGAGTTAAAGG	PRKACB	ENSG00000142875	0.8645365827048813	[264]	[209]	7	hSpCas9	negative selection	10894432
84196721	84196744	1	+	28162770	PL21	viability	TGACCATCAAGGCTATATCCAGG	PRKACB	ENSG00000142875	0.07559451655101679	[398]	[182]	0	hSpCas9	negative selection	10894433
84202679	84202702	1	+	28162770	P31FUJ	viability	TCAGGGCTACAATAAGGCAGTGG	PRKACB	ENSG00000142875	0.6925589946928656	[118]	[225]	7	hSpCas9	negative selection	11063790
84202695	84202718	1	+	28162770	P31FUJ	viability	GCAGTGGATTGGTGGGCATTAGG	PRKACB	ENSG00000142875	0.3592596886901138	[472]	[712]	4	hSpCas9	negative selection	11063791
84196667	84196690	1	-	28162770	P31FUJ	viability	AGATGAGGTCTAGTGAATGGAGG	PRKACB	ENSG00000142875	0.7914453418322989	[58]	[119]	8	hSpCas9	negative selection	11063792
84196622	84196645	1	-	28162770	P31FUJ	viability	GAGCTGCATAGAACCGTGCATGG	PRKACB	ENSG00000142875	1.0005115032994156	[187]	[441]	9	hSpCas9	negative selection	11063793
84179217	84179240	1	+	28162770	P31FUJ	viability	AAAATGGGAGAATCCAACTCAGG	PRKACB	ENSG00000142875	0.41276706101092975	[100]	[157]	4	hSpCas9	negative selection	11063794
84185120	84185143	1	+	28162770	P31FUJ	viability	GGTTATGGAATATGTCCCTGGGG	PRKACB	ENSG00000142875	-0.016723557010132832	[228]	[265]	0	hSpCas9	negative selection	11063795
84202750	84202773	1	-	28162770	P31FUJ	viability	TGGTTGGTCTGCAAAGAATGGGG	PRKACB	ENSG00000142875	0.8051456709137041	[468]	[962]	8	hSpCas9	negative selection	11063796
84182285	84182308	1	-	28162770	P31FUJ	viability	CATGGCATAATACTGTTCAGTGG	PRKACB	ENSG00000142875	0.580429283979895	[69]	[122]	6	hSpCas9	negative selection	11063797
84197741	84197764	1	+	28162770	P31FUJ	viability	GGGTTTGCCAAAAGAGTTAAAGG	PRKACB	ENSG00000142875	0.12663668537247774	[409]	[525]	1	hSpCas9	negative selection	11063798
84196721	84196744	1	+	28162770	P31FUJ	viability	TGACCATCAAGGCTATATCCAGG	PRKACB	ENSG00000142875	0.40724082149942475	[590]	[920]	4	hSpCas9	negative selection	11063799
84202679	84202702	1	+	28162770	OCIAML5	viability	TCAGGGCTACAATAAGGCAGTGG	PRKACB	ENSG00000142875	-0.09573565183085964	[73]	[124]	0	hSpCas9	negative selection	11233156
84202695	84202718	1	+	28162770	OCIAML5	viability	GCAGTGGATTGGTGGGCATTAGG	PRKACB	ENSG00000142875	0.2945259267476916	[186]	[413]	2	hSpCas9	negative selection	11233157
84196667	84196690	1	-	28162770	OCIAML5	viability	AGATGAGGTCTAGTGAATGGAGG	PRKACB	ENSG00000142875	-0.30774605464018645	[23]	[34]	-2	hSpCas9	negative selection	11233158
84196622	84196645	1	-	28162770	OCIAML5	viability	GAGCTGCATAGAACCGTGCATGG	PRKACB	ENSG00000142875	1.3453391670004224	[103]	[476]	9	hSpCas9	negative selection	11233159
84179217	84179240	1	+	28162770	OCIAML5	viability	AAAATGGGAGAATCCAACTCAGG	PRKACB	ENSG00000142875	0.10399008154840605	[49]	[96]	0	hSpCas9	negative selection	11233160
84185120	84185143	1	+	28162770	OCIAML5	viability	GGTTATGGAATATGTCCCTGGGG	PRKACB	ENSG00000142875	0.365634155147729	[131]	[306]	3	hSpCas9	negative selection	11233161
84202750	84202773	1	-	28162770	OCIAML5	viability	TGGTTGGTCTGCAAAGAATGGGG	PRKACB	ENSG00000142875	0.4174300855994939	[296]	[715]	3	hSpCas9	negative selection	11233162
84182285	84182308	1	-	28162770	OCIAML5	viability	CATGGCATAATACTGTTCAGTGG	PRKACB	ENSG00000142875	0.6049784549364223	[54]	[150]	5	hSpCas9	negative selection	11233163
84197741	84197764	1	+	28162770	OCIAML5	viability	GGGTTTGCCAAAAGAGTTAAAGG	PRKACB	ENSG00000142875	0.6205482039916619	[306]	[851]	5	hSpCas9	negative selection	11233164
84196721	84196744	1	+	28162770	OCIAML5	viability	TGACCATCAAGGCTATATCCAGG	PRKACB	ENSG00000142875	0.20144893846300493	[343]	[713]	1	hSpCas9	negative selection	11233165
84202679	84202702	1	+	28162770	EOL1	viability	TCAGGGCTACAATAAGGCAGTGG	PRKACB	ENSG00000142875	0.29067567036843184	[179]	[115]	2	hSpCas9	negative selection	11402522
84202695	84202718	1	+	28162770	EOL1	viability	GCAGTGGATTGGTGGGCATTAGG	PRKACB	ENSG00000142875	0.14919334820001884	[456]	[266]	1	hSpCas9	negative selection	11402523
84196667	84196690	1	-	28162770	EOL1	viability	AGATGAGGTCTAGTGAATGGAGG	PRKACB	ENSG00000142875	0.7298193791276494	[197]	[172]	6	hSpCas9	negative selection	11402524
84196622	84196645	1	-	28162770	EOL1	viability	GAGCTGCATAGAACCGTGCATGG	PRKACB	ENSG00000142875	0.35775339354830304	[433]	[292]	3	hSpCas9	negative selection	11402525
84179217	84179240	1	+	28162770	EOL1	viability	AAAATGGGAGAATCCAACTCAGG	PRKACB	ENSG00000142875	0.2523524327945662	[195]	[122]	2	hSpCas9	negative selection	11402526
84185120	84185143	1	+	28162770	EOL1	viability	GGTTATGGAATATGTCCCTGGGG	PRKACB	ENSG00000142875	0.49436678603114886	[414]	[307]	4	hSpCas9	negative selection	11402527
84202750	84202773	1	-	28162770	EOL1	viability	TGGTTGGTCTGCAAAGAATGGGG	PRKACB	ENSG00000142875	-0.2677351386679663	[568]	[248]	-2	hSpCas9	negative selection	11402528
84182285	84182308	1	-	28162770	EOL1	viability	CATGGCATAATACTGTTCAGTGG	PRKACB	ENSG00000142875	-1.6821098002499406	[66]	[10]	-8	hSpCas9	negative selection	11402529
84197741	84197764	1	+	28162770	EOL1	viability	GGGTTTGCCAAAAGAGTTAAAGG	PRKACB	ENSG00000142875	0.021149781951443847	[360]	[192]	0	hSpCas9	negative selection	11402530
84196721	84196744	1	+	28162770	EOL1	viability	TGACCATCAAGGCTATATCCAGG	PRKACB	ENSG00000142875	-0.8288122608463402	[589]	[174]	-5	hSpCas9	negative selection	11402531
84202679	84202702	1	+	28162770	MOLM13	viability	TCAGGGCTACAATAAGGCAGTGG	PRKACB	ENSG00000142875	1.0598046429075016	[137]	[207]	7	hSpCas9	negative selection	11571888
84202695	84202718	1	+	28162770	MOLM13	viability	GCAGTGGATTGGTGGGCATTAGG	PRKACB	ENSG00000142875	-0.06021078222090098	[397]	[275]	0	hSpCas9	negative selection	11571889
84196667	84196690	1	-	28162770	MOLM13	viability	AGATGAGGTCTAGTGAATGGAGG	PRKACB	ENSG00000142875	1.032093322098938	[139]	[206]	7	hSpCas9	negative selection	11571890
84196622	84196645	1	-	28162770	MOLM13	viability	GAGCTGCATAGAACCGTGCATGG	PRKACB	ENSG00000142875	1.0639191861685717	[302]	[457]	7	hSpCas9	negative selection	11571891
84179217	84179240	1	+	28162770	MOLM13	viability	AAAATGGGAGAATCCAACTCAGG	PRKACB	ENSG00000142875	0.29490458035320827	[176]	[156]	2	hSpCas9	negative selection	11571892
84185120	84185143	1	+	28162770	MOLM13	viability	GGTTATGGAATATGTCCCTGGGG	PRKACB	ENSG00000142875	0.3959964630627932	[287]	[273]	3	hSpCas9	negative selection	11571893
84202750	84202773	1	-	28162770	MOLM13	viability	TGGTTGGTCTGCAAAGAATGGGG	PRKACB	ENSG00000142875	-0.24041245436948377	[597]	[365]	-1	hSpCas9	negative selection	11571894
84182285	84182308	1	-	28162770	MOLM13	viability	CATGGCATAATACTGTTCAGTGG	PRKACB	ENSG00000142875	1.1341519843675831	[91]	[145]	8	hSpCas9	negative selection	11571895
84197741	84197764	1	+	28162770	MOLM13	viability	GGGTTTGCCAAAAGAGTTAAAGG	PRKACB	ENSG00000142875	0.3227962330822018	[323]	[292]	2	hSpCas9	negative selection	11571896
84196721	84196744	1	+	28162770	MOLM13	viability	TGACCATCAAGGCTATATCCAGG	PRKACB	ENSG00000142875	-0.773118717959216	[909]	[384]	-4	hSpCas9	negative selection	11571897
84202679	84202702	1	+	28162770	HEL	viability	TCAGGGCTACAATAAGGCAGTGG	PRKACB	ENSG00000142875	-0.703036004841373	[121]	[47]	-4	hSpCas9	negative selection	11741254
84202695	84202718	1	+	28162770	HEL	viability	GCAGTGGATTGGTGGGCATTAGG	PRKACB	ENSG00000142875	-0.23696693428193127	[413]	[224]	-2	hSpCas9	negative selection	11741255
84196667	84196690	1	-	28162770	HEL	viability	AGATGAGGTCTAGTGAATGGAGG	PRKACB	ENSG00000142875	-1.4819569154489574	[156]	[35]	-7	hSpCas9	negative selection	11741256
84196622	84196645	1	-	28162770	HEL	viability	GAGCTGCATAGAACCGTGCATGG	PRKACB	ENSG00000142875	0.8342938494142117	[330]	[377]	7	hSpCas9	negative selection	11741257
84179217	84179240	1	+	28162770	HEL	viability	AAAATGGGAGAATCCAACTCAGG	PRKACB	ENSG00000142875	0.6035682347196792	[111]	[108]	5	hSpCas9	negative selection	11741258
84185120	84185143	1	+	28162770	HEL	viability	GGTTATGGAATATGTCCCTGGGG	PRKACB	ENSG00000142875	-0.1845845062898433	[290]	[163]	-1	hSpCas9	negative selection	11741259
84202750	84202773	1	-	28162770	HEL	viability	TGGTTGGTCTGCAAAGAATGGGG	PRKACB	ENSG00000142875	0.4803711817361266	[356]	[318]	4	hSpCas9	negative selection	11741260
84182285	84182308	1	-	28162770	HEL	viability	CATGGCATAATACTGTTCAGTGG	PRKACB	ENSG00000142875	-0.7134049782249183	[63]	[24]	-5	hSpCas9	negative selection	11741261
84197741	84197764	1	+	28162770	HEL	viability	GGGTTTGCCAAAAGAGTTAAAGG	PRKACB	ENSG00000142875	-0.17184765928832302	[349]	[198]	-1	hSpCas9	negative selection	11741262
84196721	84196744	1	+	28162770	HEL	viability	TGACCATCAAGGCTATATCCAGG	PRKACB	ENSG00000142875	-0.38310117293490253	[675]	[331]	-3	hSpCas9	negative selection	11741263
84202679	84202702	1	+	28162770	MV411	viability	TCAGGGCTACAATAAGGCAGTGG	PRKACB	ENSG00000142875	-0.26223682263414383	[83]	[58]	-2	hSpCas9	negative selection	11910620
84202695	84202718	1	+	28162770	MV411	viability	GCAGTGGATTGGTGGGCATTAGG	PRKACB	ENSG00000142875	0.35037107312622484	[310]	[333]	3	hSpCas9	negative selection	11910621
84196667	84196690	1	-	28162770	MV411	viability	AGATGAGGTCTAGTGAATGGAGG	PRKACB	ENSG00000142875	-0.40463914579691795	[120]	[76]	-3	hSpCas9	negative selection	11910622
84196622	84196645	1	-	28162770	MV411	viability	GAGCTGCATAGAACCGTGCATGG	PRKACB	ENSG00000142875	0.9889758747388055	[188]	[315]	8	hSpCas9	negative selection	11910623
84179217	84179240	1	+	28162770	MV411	viability	AAAATGGGAGAATCCAACTCAGG	PRKACB	ENSG00000142875	0.7135226556520116	[117]	[162]	6	hSpCas9	negative selection	11910624
84185120	84185143	1	+	28162770	MV411	viability	GGTTATGGAATATGTCCCTGGGG	PRKACB	ENSG00000142875	0.9097057776713804	[217]	[344]	7	hSpCas9	negative selection	11910625
84202750	84202773	1	-	28162770	MV411	viability	TGGTTGGTCTGCAAAGAATGGGG	PRKACB	ENSG00000142875	0.055403913850120445	[336]	[294]	0	hSpCas9	negative selection	11910626
84182285	84182308	1	-	28162770	MV411	viability	CATGGCATAATACTGTTCAGTGG	PRKACB	ENSG00000142875	0.6166713604484946	[47]	[61]	5	hSpCas9	negative selection	11910627
84197741	84197764	1	+	28162770	MV411	viability	GGGTTTGCCAAAAGAGTTAAAGG	PRKACB	ENSG00000142875	0.9844031449489812	[251]	[419]	8	hSpCas9	negative selection	11910628
84196721	84196744	1	+	28162770	MV411	viability	TGACCATCAAGGCTATATCCAGG	PRKACB	ENSG00000142875	0.31586269179365933	[349]	[366]	3	hSpCas9	negative selection	11910629
84202679	84202702	1	+	28162770	MONOMAC1	viability	TCAGGGCTACAATAAGGCAGTGG	PRKACB	ENSG00000142875	-0.04053236137956301	[95]	[106]	0	hSpCas9	negative selection	12079986
84202695	84202718	1	+	28162770	MONOMAC1	viability	GCAGTGGATTGGTGGGCATTAGG	PRKACB	ENSG00000142875	-0.1054063715939853	[182]	[194]	-1	hSpCas9	negative selection	12079987
84196667	84196690	1	-	28162770	MONOMAC1	viability	AGATGAGGTCTAGTGAATGGAGG	PRKACB	ENSG00000142875	0.2927684206212624	[46]	[65]	3	hSpCas9	negative selection	12079988
84196622	84196645	1	-	28162770	MONOMAC1	viability	GAGCTGCATAGAACCGTGCATGG	PRKACB	ENSG00000142875	0.23252106995800204	[172]	[232]	2	hSpCas9	negative selection	12079989
84179217	84179240	1	+	28162770	MONOMAC1	viability	AAAATGGGAGAATCCAACTCAGG	PRKACB	ENSG00000142875	0.1598976976557217	[56]	[72]	1	hSpCas9	negative selection	12079990
84185120	84185143	1	+	28162770	MONOMAC1	viability	GGTTATGGAATATGTCCCTGGGG	PRKACB	ENSG00000142875	0.2451058823818879	[144]	[196]	2	hSpCas9	negative selection	12079991
84202750	84202773	1	-	28162770	MONOMAC1	viability	TGGTTGGTCTGCAAAGAATGGGG	PRKACB	ENSG00000142875	0.29670089361506413	[271]	[382]	3	hSpCas9	negative selection	12079992
84182285	84182308	1	-	28162770	MONOMAC1	viability	CATGGCATAATACTGTTCAGTGG	PRKACB	ENSG00000142875	1.0064965470255782	[32]	[75]	8	hSpCas9	negative selection	12079993
84197741	84197764	1	+	28162770	MONOMAC1	viability	GGGTTTGCCAAAAGAGTTAAAGG	PRKACB	ENSG00000142875	1.0527414620719735	[163]	[389]	8	hSpCas9	negative selection	12079994
84196721	84196744	1	+	28162770	MONOMAC1	viability	TGACCATCAAGGCTATATCCAGG	PRKACB	ENSG00000142875	0.8987687396914463	[283]	[606]	8	hSpCas9	negative selection	12079995
84202679	84202702	1	+	28162770	OCIAML2	viability	TCAGGGCTACAATAAGGCAGTGG	PRKACB	ENSG00000142875	0.7688361094532283	[17]	[169]	7	hSpCas9	negative selection	12249352
84202695	84202718	1	+	28162770	OCIAML2	viability	GCAGTGGATTGGTGGGCATTAGG	PRKACB	ENSG00000142875	0.529370174757839	[56]	[455]	5	hSpCas9	negative selection	12249353
84196667	84196690	1	-	28162770	OCIAML2	viability	AGATGAGGTCTAGTGAATGGAGG	PRKACB	ENSG00000142875	1.0371648149565351	[15]	[181]	8	hSpCas9	negative selection	12249354
84196622	84196645	1	-	28162770	OCIAML2	viability	GAGCTGCATAGAACCGTGCATGG	PRKACB	ENSG00000142875	0.5746941652673292	[46]	[387]	5	hSpCas9	negative selection	12249355
84179217	84179240	1	+	28162770	OCIAML2	viability	AAAATGGGAGAATCCAACTCAGG	PRKACB	ENSG00000142875	0.09230636914899604	[21]	[129]	0	hSpCas9	negative selection	12249356
84185120	84185143	1	+	28162770	OCIAML2	viability	GGTTATGGAATATGTCCCTGGGG	PRKACB	ENSG00000142875	-0.2839291110490219	[37]	[172]	-2	hSpCas9	negative selection	12249357
84202750	84202773	1	-	28162770	OCIAML2	viability	TGGTTGGTCTGCAAAGAATGGGG	PRKACB	ENSG00000142875	0.9532702427464788	[70]	[761]	8	hSpCas9	negative selection	12249358
84182285	84182308	1	-	28162770	OCIAML2	viability	CATGGCATAATACTGTTCAGTGG	PRKACB	ENSG00000142875	-0.9470678691851482	[15]	[45]	-6	hSpCas9	negative selection	12249359
84197741	84197764	1	+	28162770	OCIAML2	viability	GGGTTTGCCAAAAGAGTTAAAGG	PRKACB	ENSG00000142875	-0.19903340590494334	[69]	[337]	-2	hSpCas9	negative selection	12249360
84196721	84196744	1	+	28162770	OCIAML2	viability	TGACCATCAAGGCTATATCCAGG	PRKACB	ENSG00000142875	0.4056348063355939	[72]	[535]	4	hSpCas9	negative selection	12249361
84202679	84202702	1	+	28162770	OCIAML3	viability	TCAGGGCTACAATAAGGCAGTGG	PRKACB	ENSG00000142875	2.472081550133609	[19]	[334]	9	hSpCas9	negative selection	12418718
84202695	84202718	1	+	28162770	OCIAML3	viability	GCAGTGGATTGGTGGGCATTAGG	PRKACB	ENSG00000142875	0.589592298015226	[69]	[317]	5	hSpCas9	negative selection	12418719
84196667	84196690	1	-	28162770	OCIAML3	viability	AGATGAGGTCTAGTGAATGGAGG	PRKACB	ENSG00000142875	0.44781253537046406	[16]	[69]	4	hSpCas9	negative selection	12418720
84196622	84196645	1	-	28162770	OCIAML3	viability	GAGCTGCATAGAACCGTGCATGG	PRKACB	ENSG00000142875	0.1221993936752458	[76]	[252]	1	hSpCas9	negative selection	12418721
84179217	84179240	1	+	28162770	OCIAML3	viability	AAAATGGGAGAATCCAACTCAGG	PRKACB	ENSG00000142875	0.36240309112815405	[41]	[162]	3	hSpCas9	negative selection	12418722
84185120	84185143	1	+	28162770	OCIAML3	viability	GGTTATGGAATATGTCCCTGGGG	PRKACB	ENSG00000142875	-1.2272253096525403	[75]	[97]	-7	hSpCas9	negative selection	12418723
84202750	84202773	1	-	28162770	OCIAML3	viability	TGGTTGGTCTGCAAAGAATGGGG	PRKACB	ENSG00000142875	0.1248106071317836	[119]	[394]	1	hSpCas9	negative selection	12418724
84182285	84182308	1	-	28162770	OCIAML3	viability	CATGGCATAATACTGTTCAGTGG	PRKACB	ENSG00000142875	-0.34025104807838025	[12]	[30]	-3	hSpCas9	negative selection	12418725
84197741	84197764	1	+	28162770	OCIAML3	viability	GGGTTTGCCAAAAGAGTTAAAGG	PRKACB	ENSG00000142875	0.7404113987463959	[91]	[463]	6	hSpCas9	negative selection	12418726
84196721	84196744	1	+	28162770	OCIAML3	viability	TGACCATCAAGGCTATATCCAGG	PRKACB	ENSG00000142875	0.2313138282628897	[113]	[403]	2	hSpCas9	negative selection	12418727