Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:5575
• Symbol:PRKAR1B
• Description:protein kinase cAMP-dependent type I regulatory subunit beta

DataSource: http://genomecrispr.dkfz.de/#!/results/PRKAR1B

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
711337	711360	7	+	26472758	Jiyoye	viability	GCTTCTCGAAGTGCTCCCGGAGG	PRKAR1B	ENSG00000188191	0.20750303666950914	[146]	[127]	1	hSpCas9	negative selection	127363
680700	680723	7	-	26472758	Jiyoye	viability	AAAACAGGCAGATTTTGGCGCGG	PRKAR1B	ENSG00000188191	-1.14031241379662	[113]	[38]	-7	hSpCas9	negative selection	127364
596264	596287	7	-	26472758	Jiyoye	viability	TGGGTGACCAACATCAGCGAGGG	PRKAR1B	ENSG00000188191	0.4937630665019642	[96]	[102]	4	hSpCas9	negative selection	127365
680582	680605	7	-	26472758	Jiyoye	viability	GAGTGCCGAGGTGTACACCGAGG	PRKAR1B	ENSG00000188191	3.764727386123957	[11]	[122]	9	hSpCas9	negative selection	127366
579345	579368	7	-	26472758	Jiyoye	viability	GAAGTGGGAGCGTCTGACCGTGG	PRKAR1B	ENSG00000188191	1.0446053021211654	[17]	[27]	7	hSpCas9	negative selection	127367
579328	579351	7	+	26472758	Jiyoye	viability	GGGCTCCAGCGCATCCGCCACGG	PRKAR1B	ENSG00000188191	-0.47229095318663783	[240]	[130]	-3	hSpCas9	negative selection	127368
551381	551404	7	+	26472758	Jiyoye	viability	GGACTCACCGAAGTAGTCAGAGG	PRKAR1B	ENSG00000188191	0.03520660411891563	[197]	[152]	0	hSpCas9	negative selection	127369
711457	711480	7	-	26472758	Jiyoye	viability	GGAGGAGGACGAGAGCCTGAAGG	PRKAR1B	ENSG00000188191	0.8388916219313476	[42]	[57]	6	hSpCas9	negative selection	127370
711418	711441	7	-	26472758	Jiyoye	viability	GCAGCTGCACGGGATCCAGCAGG	PRKAR1B	ENSG00000188191	-0.31180446718697036	[185]	[112]	-2	hSpCas9	negative selection	127371
711373	711396	7	+	26472758	Jiyoye	viability	GTTCGGGCTTGGAGATGCAGAGG	PRKAR1B	ENSG00000188191	0.14915905043870414	[286]	[239]	1	hSpCas9	negative selection	127372
711337	711360	7	+	26472758	KBM7	viability	GCTTCTCGAAGTGCTCCCGGAGG	PRKAR1B	ENSG00000188191	0.12228651580104333	[628,371]	[256,244]	1	hSpCas9	negative selection	318481
680700	680723	7	-	26472758	KBM7	viability	AAAACAGGCAGATTTTGGCGCGG	PRKAR1B	ENSG00000188191	0.7828437318110897	[622,418]	[422,407]	8	hSpCas9	negative selection	318482
596264	596287	7	-	26472758	KBM7	viability	TGGGTGACCAACATCAGCGAGGG	PRKAR1B	ENSG00000188191	0.11476241539820439	[503,386]	[283,171]	1	hSpCas9	negative selection	318483
680582	680605	7	-	26472758	KBM7	viability	GAGTGCCGAGGTGTACACCGAGG	PRKAR1B	ENSG00000188191	1.5690583748528855	[409,308]	[519,475]	9	hSpCas9	negative selection	318484
579345	579368	7	-	26472758	KBM7	viability	GAAGTGGGAGCGTCTGACCGTGG	PRKAR1B	ENSG00000188191	0.9774755816997753	[186,66]	[46,170]	9	hSpCas9	negative selection	318485
579328	579351	7	+	26472758	KBM7	viability	GGGCTCCAGCGCATCCGCCACGG	PRKAR1B	ENSG00000188191	0.5141352470546955	[599,367]	[306,328]	5	hSpCas9	negative selection	318486
551381	551404	7	+	26472758	KBM7	viability	GGACTCACCGAAGTAGTCAGAGG	PRKAR1B	ENSG00000188191	0.20905533102886387	[783,640]	[419,353]	2	hSpCas9	negative selection	318487
711457	711480	7	-	26472758	KBM7	viability	GGAGGAGGACGAGAGCCTGAAGG	PRKAR1B	ENSG00000188191	-0.009507837753697013	[413,290]	[199,128]	0	hSpCas9	negative selection	318488
711418	711441	7	-	26472758	KBM7	viability	GCAGCTGCACGGGATCCAGCAGG	PRKAR1B	ENSG00000188191	0.8055093715543847	[610,416]	[372,454]	8	hSpCas9	negative selection	318489
711373	711396	7	+	26472758	KBM7	viability	GTTCGGGCTTGGAGATGCAGAGG	PRKAR1B	ENSG00000188191	0.5222196217019643	[1202,841]	[636,720]	5	hSpCas9	negative selection	318490
711337	711360	7	+	26472758	Raji	viability	GCTTCTCGAAGTGCTCCCGGAGG	PRKAR1B	ENSG00000188191	-0.3315007058596121	[243]	[44]	-3	hSpCas9	negative selection	509599
680700	680723	7	-	26472758	Raji	viability	AAAACAGGCAGATTTTGGCGCGG	PRKAR1B	ENSG00000188191	0.07528269220657535	[408]	[99]	0	hSpCas9	negative selection	509600
596264	596287	7	-	26472758	Raji	viability	TGGGTGACCAACATCAGCGAGGG	PRKAR1B	ENSG00000188191	-0.6249206814227438	[205]	[30]	-5	hSpCas9	negative selection	509601
680582	680605	7	-	26472758	Raji	viability	GAGTGCCGAGGTGTACACCGAGG	PRKAR1B	ENSG00000188191	1.1405503993087986	[85]	[43]	8	hSpCas9	negative selection	509602
579345	579368	7	-	26472758	Raji	viability	GAAGTGGGAGCGTCTGACCGTGG	PRKAR1B	ENSG00000188191	0.7013911756977627	[52]	[19]	6	hSpCas9	negative selection	509603
579328	579351	7	+	26472758	Raji	viability	GGGCTCCAGCGCATCCGCCACGG	PRKAR1B	ENSG00000188191	1.0260834332717512	[145]	[68]	8	hSpCas9	negative selection	509604
551381	551404	7	+	26472758	Raji	viability	GGACTCACCGAAGTAGTCAGAGG	PRKAR1B	ENSG00000188191	0.3845306775335494	[372]	[112]	3	hSpCas9	negative selection	509605
711457	711480	7	-	26472758	Raji	viability	GGAGGAGGACGAGAGCCTGAAGG	PRKAR1B	ENSG00000188191	-0.21454455951376283	[129]	[25]	-2	hSpCas9	negative selection	509606
711418	711441	7	-	26472758	Raji	viability	GCAGCTGCACGGGATCCAGCAGG	PRKAR1B	ENSG00000188191	-0.2747620823478696	[317]	[60]	-2	hSpCas9	negative selection	509607
711373	711396	7	+	26472758	Raji	viability	GTTCGGGCTTGGAGATGCAGAGG	PRKAR1B	ENSG00000188191	0.7270131679835756	[465]	[178]	6	hSpCas9	negative selection	509608
711337	711360	7	+	26472758	K562	viability	GCTTCTCGAAGTGCTCCCGGAGG	PRKAR1B	ENSG00000188191	0.9510334946451808	[268]	[438]	7	hSpCas9	negative selection	700717
680700	680723	7	-	26472758	K562	viability	AAAACAGGCAGATTTTGGCGCGG	PRKAR1B	ENSG00000188191	0.6663756408850814	[467]	[626]	5	hSpCas9	negative selection	700718
596264	596287	7	-	26472758	K562	viability	TGGGTGACCAACATCAGCGAGGG	PRKAR1B	ENSG00000188191	-0.30337398046416836	[363]	[248]	-2	hSpCas9	negative selection	700719
680582	680605	7	-	26472758	K562	viability	GAGTGCCGAGGTGTACACCGAGG	PRKAR1B	ENSG00000188191	0.4221043451375088	[205]	[232]	3	hSpCas9	negative selection	700720
579345	579368	7	-	26472758	K562	viability	GAAGTGGGAGCGTCTGACCGTGG	PRKAR1B	ENSG00000188191	-0.2953145190617117	[156]	[107]	-2	hSpCas9	negative selection	700721
579328	579351	7	+	26472758	K562	viability	GGGCTCCAGCGCATCCGCCACGG	PRKAR1B	ENSG00000188191	0.12524702668876936	[390]	[359]	0	hSpCas9	negative selection	700722
551381	551404	7	+	26472758	K562	viability	GGACTCACCGAAGTAGTCAGAGG	PRKAR1B	ENSG00000188191	0.6655222276446449	[533]	[714]	5	hSpCas9	negative selection	700723
711457	711480	7	-	26472758	K562	viability	GGAGGAGGACGAGAGCCTGAAGG	PRKAR1B	ENSG00000188191	0.5423235933472931	[217]	[267]	4	hSpCas9	negative selection	700724
711418	711441	7	-	26472758	K562	viability	GCAGCTGCACGGGATCCAGCAGG	PRKAR1B	ENSG00000188191	0.0308232545671579	[326]	[281]	0	hSpCas9	negative selection	700725
711373	711396	7	+	26472758	K562	viability	GTTCGGGCTTGGAGATGCAGAGG	PRKAR1B	ENSG00000188191	1.0028883045754617	[878]	[1486]	8	hSpCas9	negative selection	700726
579361	579384	7	-	26627737	DLD1	viability	CGACAGAGTCCCTGGAGAAGTGG	PRKAR1B	ENSG00000188191	0.08343699793997006	[1385]	[350,605,430]	0	hSpCas9	negative selection	836832
596264	596287	7	-	26627737	DLD1	viability	TGGGTGACCAACATCAGCGAGGG	PRKAR1B	ENSG00000188191	0.10341258340432147	[886]	[319,375,213]	1	hSpCas9	negative selection	836840
677278	677301	7	-	26627737	DLD1	viability	AACCATGACTGCGCTGGCCAAGG	PRKAR1B	ENSG00000188191	-0.28382125806774794	[1637]	[311,482,462]	-3	hSpCas9	negative selection	836917
680579	680602	7	-	26627737	DLD1	viability	TGCCGAGGTGTACACCGAGGAGG	PRKAR1B	ENSG00000188191	-0.7618683236664746	[255]	[80,5,51]	-6	hSpCas9	negative selection	836921
711337	711360	7	+	26627737	DLD1	viability	GCTTCTCGAAGTGCTCCCGGAGG	PRKAR1B	ENSG00000188191	0.9359040146309094	[220]	[190,106,101]	8	hSpCas9	negative selection	837054
711463	711486	7	+	26627737	DLD1	viability	GGCTCTCGTCCTCCTCCGAGGGG	PRKAR1B	ENSG00000188191	-0.3500679818868444	[225]	[33,52,75]	-4	hSpCas9	negative selection	837055
579361	579384	7	-	26627737	GBM cells	viability after 5 days	CGACAGAGTCCCTGGAGAAGTGG	PRKAR1B	ENSG00000188191	0.1003669585297704	[693]	[396,400]	1	hSpCas9	negative selection	919147
596264	596287	7	-	26627737	GBM cells	viability after 5 days	TGGGTGACCAACATCAGCGAGGG	PRKAR1B	ENSG00000188191	-0.467658135056519	[360]	[126,152]	-6	hSpCas9	negative selection	919155
677278	677301	7	-	26627737	GBM cells	viability after 5 days	AACCATGACTGCGCTGGCCAAGG	PRKAR1B	ENSG00000188191	0.7316952564656924	[465]	[432,396]	8	hSpCas9	negative selection	919232
680579	680602	7	-	26627737	GBM cells	viability after 5 days	TGCCGAGGTGTACACCGAGGAGG	PRKAR1B	ENSG00000188191	-0.2977780361194122	[101]	[39,48]	-5	hSpCas9	negative selection	919236
711337	711360	7	+	26627737	GBM cells	viability after 5 days	GCTTCTCGAAGTGCTCCCGGAGG	PRKAR1B	ENSG00000188191	-0.7988165559974203	[132]	[58,22]	-8	hSpCas9	negative selection	919369
711463	711486	7	+	26627737	GBM cells	viability after 5 days	GGCTCTCGTCCTCCTCCGAGGGG	PRKAR1B	ENSG00000188191	-0.4359532757091752	[139]	[59,50]	-6	hSpCas9	negative selection	919370
579361	579384	7	-	26627737	GBM cells	viability after 13 days	CGACAGAGTCCCTGGAGAAGTGG	PRKAR1B	ENSG00000188191	0.02506569186660279	[693]	[402,366]	0	hSpCas9	negative selection	1001462
596264	596287	7	-	26627737	GBM cells	viability after 13 days	TGGGTGACCAACATCAGCGAGGG	PRKAR1B	ENSG00000188191	-0.34345657683668346	[360]	[219,100]	-4	hSpCas9	negative selection	1001470
677278	677301	7	-	26627737	GBM cells	viability after 13 days	AACCATGACTGCGCTGGCCAAGG	PRKAR1B	ENSG00000188191	0.7813978790182423	[465]	[572,321]	8	hSpCas9	negative selection	1001547
680579	680602	7	-	26627737	GBM cells	viability after 13 days	TGCCGAGGTGTACACCGAGGAGG	PRKAR1B	ENSG00000188191	0.2809823949926913	[101]	[69,64]	3	hSpCas9	negative selection	1001551
711337	711360	7	+	26627737	GBM cells	viability after 13 days	GCTTCTCGAAGTGCTCCCGGAGG	PRKAR1B	ENSG00000188191	-0.7137476932854445	[132]	[43,43]	-7	hSpCas9	negative selection	1001684
711463	711486	7	+	26627737	GBM cells	viability after 13 days	GGCTCTCGTCCTCCTCCGAGGGG	PRKAR1B	ENSG00000188191	-0.5136660419956175	[139]	[50,54]	-6	hSpCas9	negative selection	1001685
579361	579384	7	-	26627737	GBM cells	viability after 21 days	CGACAGAGTCCCTGGAGAAGTGG	PRKAR1B	ENSG00000188191	0.008510217123639974	[693]	[372,384]	0	hSpCas9	negative selection	1083777
596264	596287	7	-	26627737	GBM cells	viability after 21 days	TGGGTGACCAACATCAGCGAGGG	PRKAR1B	ENSG00000188191	-0.19683209313156114	[360]	[191,151]	-2	hSpCas9	negative selection	1083785
677278	677301	7	-	26627737	GBM cells	viability after 21 days	AACCATGACTGCGCTGGCCAAGG	PRKAR1B	ENSG00000188191	1.0629892414981401	[465]	[553,505]	9	hSpCas9	negative selection	1083862
680579	680602	7	-	26627737	GBM cells	viability after 21 days	TGCCGAGGTGTACACCGAGGAGG	PRKAR1B	ENSG00000188191	-0.03611762524192663	[101]	[52,54]	0	hSpCas9	negative selection	1083866
711337	711360	7	+	26627737	GBM cells	viability after 21 days	GCTTCTCGAAGTGCTCCCGGAGG	PRKAR1B	ENSG00000188191	-1.482026889306922	[132]	[28,22]	-8	hSpCas9	negative selection	1083999
711463	711486	7	+	26627737	GBM cells	viability after 21 days	GGCTCTCGTCCTCCTCCGAGGGG	PRKAR1B	ENSG00000188191	0.02500482382963254	[139]	[79,74]	0	hSpCas9	negative selection	1084000
579361	579384	7	-	26627737	RPE1	viability after 9 days	CGACAGAGTCCCTGGAGAAGTGG	PRKAR1B	ENSG00000188191	-0.3835632153968589	[3209]	[720,833]	-3	hSpCas9	negative selection	1166092
596264	596287	7	-	26627737	RPE1	viability after 9 days	TGGGTGACCAACATCAGCGAGGG	PRKAR1B	ENSG00000188191	0.23061533597000017	[1509]	[548,561]	1	hSpCas9	negative selection	1166100
677278	677301	7	-	26627737	RPE1	viability after 9 days	AACCATGACTGCGCTGGCCAAGG	PRKAR1B	ENSG00000188191	1.8199676800177682	[1068]	[1185,1175]	8	hSpCas9	negative selection	1166177
680579	680602	7	-	26627737	RPE1	viability after 9 days	TGCCGAGGTGTACACCGAGGAGG	PRKAR1B	ENSG00000188191	0.7511478794208764	[639]	[362,303]	5	hSpCas9	negative selection	1166181
711337	711360	7	+	26627737	RPE1	viability after 9 days	GCTTCTCGAAGTGCTCCCGGAGG	PRKAR1B	ENSG00000188191	-1.1275854045066351	[703]	[99,101]	-7	hSpCas9	negative selection	1166314
711463	711486	7	+	26627737	RPE1	viability after 9 days	GGCTCTCGTCCTCCTCCGAGGGG	PRKAR1B	ENSG00000188191	-1.1739657864352395	[450]	[38,92]	-7	hSpCas9	negative selection	1166315
579361	579384	7	-	26627737	RPE1	viability after 12 days	CGACAGAGTCCCTGGAGAAGTGG	PRKAR1B	ENSG00000188191	-0.5352232304596884	[3209]	[513,680]	-4	hSpCas9	negative selection	1248407
596264	596287	7	-	26627737	RPE1	viability after 12 days	TGGGTGACCAACATCAGCGAGGG	PRKAR1B	ENSG00000188191	-0.218201564410879	[1509]	[339,357]	-1	hSpCas9	negative selection	1248415
677278	677301	7	-	26627737	RPE1	viability after 12 days	AACCATGACTGCGCTGGCCAAGG	PRKAR1B	ENSG00000188191	1.7428009953055323	[1068]	[849,1078]	8	hSpCas9	negative selection	1248492
680579	680602	7	-	26627737	RPE1	viability after 12 days	TGCCGAGGTGTACACCGAGGAGG	PRKAR1B	ENSG00000188191	0.6190457676013168	[639]	[300,224]	4	hSpCas9	negative selection	1248496
711337	711360	7	+	26627737	RPE1	viability after 12 days	GCTTCTCGAAGTGCTCCCGGAGG	PRKAR1B	ENSG00000188191	-1.609788886236852	[703]	[111,8]	-8	hSpCas9	negative selection	1248629
711463	711486	7	+	26627737	RPE1	viability after 12 days	GGCTCTCGTCCTCCTCCGAGGGG	PRKAR1B	ENSG00000188191	-0.46660229806072484	[450]	[93,80]	-3	hSpCas9	negative selection	1248630
579361	579384	7	-	26627737	RPE1	viability after 15 days	CGACAGAGTCCCTGGAGAAGTGG	PRKAR1B	ENSG00000188191	-0.4434615558867727	[3209]	[625,707]	-3	hSpCas9	negative selection	1330722
596264	596287	7	-	26627737	RPE1	viability after 15 days	TGGGTGACCAACATCAGCGAGGG	PRKAR1B	ENSG00000188191	-0.10291097481384959	[1509]	[524,274]	0	hSpCas9	negative selection	1330730
677278	677301	7	-	26627737	RPE1	viability after 15 days	AACCATGACTGCGCTGGCCAAGG	PRKAR1B	ENSG00000188191	2.1410181180532337	[1068]	[1654,1023]	9	hSpCas9	negative selection	1330807
680579	680602	7	-	26627737	RPE1	viability after 15 days	TGCCGAGGTGTACACCGAGGAGG	PRKAR1B	ENSG00000188191	0.7250772980394202	[639]	[368,231]	4	hSpCas9	negative selection	1330811
711337	711360	7	+	26627737	RPE1	viability after 15 days	GCTTCTCGAAGTGCTCCCGGAGG	PRKAR1B	ENSG00000188191	-1.079140826447655	[703]	[135,53]	-6	hSpCas9	negative selection	1330944
711463	711486	7	+	26627737	RPE1	viability after 15 days	GGCTCTCGTCCTCCTCCGAGGGG	PRKAR1B	ENSG00000188191	0.053356914515624965	[450]	[166,98]	0	hSpCas9	negative selection	1330945
579361	579384	7	-	26627737	RPE1	viability after 18 days	CGACAGAGTCCCTGGAGAAGTGG	PRKAR1B	ENSG00000188191	-0.3010847608932963	[3209]	[749,652]	-2	hSpCas9	negative selection	1413037
596264	596287	7	-	26627737	RPE1	viability after 18 days	TGGGTGACCAACATCAGCGAGGG	PRKAR1B	ENSG00000188191	0.12951461081557392	[1509]	[482,405]	0	hSpCas9	negative selection	1413045
677278	677301	7	-	26627737	RPE1	viability after 18 days	AACCATGACTGCGCTGGCCAAGG	PRKAR1B	ENSG00000188191	1.6929742649758264	[1068]	[910,955]	8	hSpCas9	negative selection	1413122
680579	680602	7	-	26627737	RPE1	viability after 18 days	TGCCGAGGTGTACACCGAGGAGG	PRKAR1B	ENSG00000188191	0.6689379402599416	[639]	[262,286]	4	hSpCas9	negative selection	1413126
711337	711360	7	+	26627737	RPE1	viability after 18 days	GCTTCTCGAAGTGCTCCCGGAGG	PRKAR1B	ENSG00000188191	-1.3404889122191965	[703]	[133,11]	-7	hSpCas9	negative selection	1413259
711463	711486	7	+	26627737	RPE1	viability after 18 days	GGCTCTCGTCCTCCTCCGAGGGG	PRKAR1B	ENSG00000188191	-0.8024345382566381	[450]	[48,91]	-5	hSpCas9	negative selection	1413260
579361	579384	7	-	26627737	HeLa	viability after 8 days	CGACAGAGTCCCTGGAGAAGTGG	PRKAR1B	ENSG00000188191	0.49781556824370665	[895]	[947,579,233]	4	hSpCas9	negative selection	1495352
596264	596287	7	-	26627737	HeLa	viability after 8 days	TGGGTGACCAACATCAGCGAGGG	PRKAR1B	ENSG00000188191	-0.1927961545848662	[957]	[320,568,205]	-2	hSpCas9	negative selection	1495360
677278	677301	7	-	26627737	HeLa	viability after 8 days	AACCATGACTGCGCTGGCCAAGG	PRKAR1B	ENSG00000188191	0.5497459621752402	[766]	[464,588,411]	5	hSpCas9	negative selection	1495437
680579	680602	7	-	26627737	HeLa	viability after 8 days	TGCCGAGGTGTACACCGAGGAGG	PRKAR1B	ENSG00000188191	1.417173846282192	[189]	[630,53,77]	8	hSpCas9	negative selection	1495441
711337	711360	7	+	26627737	HeLa	viability after 8 days	GCTTCTCGAAGTGCTCCCGGAGG	PRKAR1B	ENSG00000188191	-1.0277796193103097	[466]	[167,30,113]	-8	hSpCas9	negative selection	1495574
711463	711486	7	+	26627737	HeLa	viability after 8 days	GGCTCTCGTCCTCCTCCGAGGGG	PRKAR1B	ENSG00000188191	0.11011643734637888	[190]	[131,94,53]	1	hSpCas9	negative selection	1495575
579361	579384	7	-	26627737	HeLa	viability after 12 days	CGACAGAGTCCCTGGAGAAGTGG	PRKAR1B	ENSG00000188191	0.025171899796340824	[895]	[464,385,280]	0	hSpCas9	negative selection	1577667
596264	596287	7	-	26627737	HeLa	viability after 12 days	TGGGTGACCAACATCAGCGAGGG	PRKAR1B	ENSG00000188191	-0.6353447131330742	[957]	[314,267,181]	-5	hSpCas9	negative selection	1577675
677278	677301	7	-	26627737	HeLa	viability after 12 days	AACCATGACTGCGCTGGCCAAGG	PRKAR1B	ENSG00000188191	0.673729602189954	[766]	[457,519,535]	5	hSpCas9	negative selection	1577752
680579	680602	7	-	26627737	HeLa	viability after 12 days	TGCCGAGGTGTACACCGAGGAGG	PRKAR1B	ENSG00000188191	0.04528217138741408	[189]	[100,39,106]	0	hSpCas9	negative selection	1577756
711337	711360	7	+	26627737	HeLa	viability after 12 days	GCTTCTCGAAGTGCTCCCGGAGG	PRKAR1B	ENSG00000188191	-1.3802963654353708	[466]	[7,40,174]	-8	hSpCas9	negative selection	1577889
711463	711486	7	+	26627737	HeLa	viability after 12 days	GGCTCTCGTCCTCCTCCGAGGGG	PRKAR1B	ENSG00000188191	-0.6496503095323256	[190]	[12,48,87]	-5	hSpCas9	negative selection	1577890
579361	579384	7	-	26627737	HeLa	viability after 15 days	CGACAGAGTCCCTGGAGAAGTGG	PRKAR1B	ENSG00000188191	0.011335984495641327	[895]	[229,430,449]	0	hSpCas9	negative selection	1659982
596264	596287	7	-	26627737	HeLa	viability after 15 days	TGGGTGACCAACATCAGCGAGGG	PRKAR1B	ENSG00000188191	-0.15538320912989345	[957]	[506,245,290]	-1	hSpCas9	negative selection	1659990
677278	677301	7	-	26627737	HeLa	viability after 15 days	AACCATGACTGCGCTGGCCAAGG	PRKAR1B	ENSG00000188191	0.9111492942965124	[766]	[529,479,765]	7	hSpCas9	negative selection	1660067
680579	680602	7	-	26627737	HeLa	viability after 15 days	TGCCGAGGTGTACACCGAGGAGG	PRKAR1B	ENSG00000188191	0.19564184951117003	[189]	[114,102,43]	1	hSpCas9	negative selection	1660071
711337	711360	7	+	26627737	HeLa	viability after 15 days	GCTTCTCGAAGTGCTCCCGGAGG	PRKAR1B	ENSG00000188191	-0.9362949845128965	[466]	[190,16,87]	-7	hSpCas9	negative selection	1660204
711463	711486	7	+	26627737	HeLa	viability after 15 days	GGCTCTCGTCCTCCTCCGAGGGG	PRKAR1B	ENSG00000188191	0.4115509526946107	[190]	[109,86,113]	3	hSpCas9	negative selection	1660205
579361	579384	7	-	26627737	HeLa	viability after 18 days	CGACAGAGTCCCTGGAGAAGTGG	PRKAR1B	ENSG00000188191	-0.020124768772812773	[895]	[149,342,449]	0	hSpCas9	negative selection	1742297
596264	596287	7	-	26627737	HeLa	viability after 18 days	TGGGTGACCAACATCAGCGAGGG	PRKAR1B	ENSG00000188191	-0.11968708032470898	[957]	[352,208,290]	-1	hSpCas9	negative selection	1742305
677278	677301	7	-	26627737	HeLa	viability after 18 days	AACCATGACTGCGCTGGCCAAGG	PRKAR1B	ENSG00000188191	0.9015498461510042	[766]	[345,399,765]	6	hSpCas9	negative selection	1742382
680579	680602	7	-	26627737	HeLa	viability after 18 days	TGCCGAGGTGTACACCGAGGAGG	PRKAR1B	ENSG00000188191	0.12889252562607667	[189]	[67,86,43]	1	hSpCas9	negative selection	1742386
711337	711360	7	+	26627737	HeLa	viability after 18 days	GCTTCTCGAAGTGCTCCCGGAGG	PRKAR1B	ENSG00000188191	-0.9053930360558875	[466]	[133,11,87]	-7	hSpCas9	negative selection	1742519
711463	711486	7	+	26627737	HeLa	viability after 18 days	GGCTCTCGTCCTCCTCCGAGGGG	PRKAR1B	ENSG00000188191	0.4564745599806237	[190]	[80,70,113]	4	hSpCas9	negative selection	1742520
579361	579384	7	-	26627737	HCT116	viability after 6 days	CGACAGAGTCCCTGGAGAAGTGG	PRKAR1B	ENSG00000188191	-0.2342358952560708	[2023]	[459,165]	-1	hSpCas9	negative selection	1824612
596264	596287	7	-	26627737	HCT116	viability after 6 days	TGGGTGACCAACATCAGCGAGGG	PRKAR1B	ENSG00000188191	0.02395604794881878	[1434]	[142,276]	0	hSpCas9	negative selection	1824620
677278	677301	7	-	26627737	HCT116	viability after 6 days	AACCATGACTGCGCTGGCCAAGG	PRKAR1B	ENSG00000188191	0.45177240563057885	[963]	[428,84]	2	hSpCas9	negative selection	1824697
680579	680602	7	-	26627737	HCT116	viability after 6 days	TGCCGAGGTGTACACCGAGGAGG	PRKAR1B	ENSG00000188191	0.5010160603414229	[247]	[69,46]	3	hSpCas9	negative selection	1824701
711337	711360	7	+	26627737	HCT116	viability after 6 days	GCTTCTCGAAGTGCTCCCGGAGG	PRKAR1B	ENSG00000188191	0.8321088190804721	[561]	[19,232]	4	hSpCas9	negative selection	1824834
711463	711486	7	+	26627737	HCT116	viability after 6 days	GGCTCTCGTCCTCCTCCGAGGGG	PRKAR1B	ENSG00000188191	1.5638574832113483	[178]	[117,63]	7	hSpCas9	negative selection	1824835
579361	579384	7	-	26627737	HCT116	viability after 8 days	CGACAGAGTCCCTGGAGAAGTGG	PRKAR1B	ENSG00000188191	-0.07567145055415736	[827]	[494,378,425]	-1	hSpCas9	negative selection	1906927
596264	596287	7	-	26627737	HCT116	viability after 8 days	TGGGTGACCAACATCAGCGAGGG	PRKAR1B	ENSG00000188191	-0.48995046833856615	[810]	[359,247,346]	-5	hSpCas9	negative selection	1906935
677278	677301	7	-	26627737	HCT116	viability after 8 days	AACCATGACTGCGCTGGCCAAGG	PRKAR1B	ENSG00000188191	0.16597173445304003	[596]	[461,370,276]	2	hSpCas9	negative selection	1907012
680579	680602	7	-	26627737	HCT116	viability after 8 days	TGCCGAGGTGTACACCGAGGAGG	PRKAR1B	ENSG00000188191	0.07437764576242879	[282]	[164,114,211]	0	hSpCas9	negative selection	1907016
711337	711360	7	+	26627737	HCT116	viability after 8 days	GCTTCTCGAAGTGCTCCCGGAGG	PRKAR1B	ENSG00000188191	1.7746076010768448	[89]	[177,228,102]	9	hSpCas9	negative selection	1907149
711463	711486	7	+	26627737	HCT116	viability after 8 days	GGCTCTCGTCCTCCTCCGAGGGG	PRKAR1B	ENSG00000188191	0.14189547048246676	[142]	[53,99,105]	1	hSpCas9	negative selection	1907150
579361	579384	7	-	26627737	HCT116	viability after 9 days	CGACAGAGTCCCTGGAGAAGTGG	PRKAR1B	ENSG00000188191	0.15930310822181304	[2023]	[936,339]	1	hSpCas9	negative selection	1989242
596264	596287	7	-	26627737	HCT116	viability after 9 days	TGGGTGACCAACATCAGCGAGGG	PRKAR1B	ENSG00000188191	-0.05732996639951815	[1434]	[570,207]	0	hSpCas9	negative selection	1989250
677278	677301	7	-	26627737	HCT116	viability after 9 days	AACCATGACTGCGCTGGCCAAGG	PRKAR1B	ENSG00000188191	1.5683720155806187	[963]	[401,1048]	8	hSpCas9	negative selection	1989327
680579	680602	7	-	26627737	HCT116	viability after 9 days	TGCCGAGGTGTACACCGAGGAGG	PRKAR1B	ENSG00000188191	1.2817103790812103	[247]	[160,160]	8	hSpCas9	negative selection	1989331
711337	711360	7	+	26627737	HCT116	viability after 9 days	GCTTCTCGAAGTGCTCCCGGAGG	PRKAR1B	ENSG00000188191	0.5232228924038939	[561]	[194,231]	4	hSpCas9	negative selection	1989464
711463	711486	7	+	26627737	HCT116	viability after 9 days	GGCTCTCGTCCTCCTCCGAGGGG	PRKAR1B	ENSG00000188191	1.2816179219464998	[178]	[37,177]	8	hSpCas9	negative selection	1989465
579361	579384	7	-	26627737	HCT116	viability after 12 days	CGACAGAGTCCCTGGAGAAGTGG	PRKAR1B	ENSG00000188191	-0.04265069473000871	[827]	[412,454,400]	0	hSpCas9	negative selection	2071557
596264	596287	7	-	26627737	HCT116	viability after 12 days	TGGGTGACCAACATCAGCGAGGG	PRKAR1B	ENSG00000188191	-0.2653860926054388	[810]	[412,286,356]	-3	hSpCas9	negative selection	2071565
677278	677301	7	-	26627737	HCT116	viability after 12 days	AACCATGACTGCGCTGGCCAAGG	PRKAR1B	ENSG00000188191	0.4273836686933028	[596]	[331,477,464]	4	hSpCas9	negative selection	2071642
680579	680602	7	-	26627737	HCT116	viability after 12 days	TGCCGAGGTGTACACCGAGGAGG	PRKAR1B	ENSG00000188191	-0.004576268569084746	[282]	[242,88,102]	0	hSpCas9	negative selection	2071646
711337	711360	7	+	26627737	HCT116	viability after 12 days	GCTTCTCGAAGTGCTCCCGGAGG	PRKAR1B	ENSG00000188191	1.98303969933623	[89]	[101,252,214]	9	hSpCas9	negative selection	2071779
711463	711486	7	+	26627737	HCT116	viability after 12 days	GGCTCTCGTCCTCCTCCGAGGGG	PRKAR1B	ENSG00000188191	-0.48907097259657406	[142]	[29,65,66]	-5	hSpCas9	negative selection	2071780
579361	579384	7	-	26627737	HCT116	viability after 15 days	CGACAGAGTCCCTGGAGAAGTGG	PRKAR1B	ENSG00000188191	0.22113622697312696	[827]	[683,303,688]	2	hSpCas9	negative selection	2153872
596264	596287	7	-	26627737	HCT116	viability after 15 days	TGGGTGACCAACATCAGCGAGGG	PRKAR1B	ENSG00000188191	-0.9666179009565173	[810]	[317,194,211]	-7	hSpCas9	negative selection	2153880
677278	677301	7	-	26627737	HCT116	viability after 15 days	AACCATGACTGCGCTGGCCAAGG	PRKAR1B	ENSG00000188191	0.6932389414709736	[596]	[611,660,398]	6	hSpCas9	negative selection	2153957
680579	680602	7	-	26627737	HCT116	viability after 15 days	TGCCGAGGTGTACACCGAGGAGG	PRKAR1B	ENSG00000188191	-0.8007211047518586	[282]	[188,46,55]	-7	hSpCas9	negative selection	2153961
711337	711360	7	+	26627737	HCT116	viability after 15 days	GCTTCTCGAAGTGCTCCCGGAGG	PRKAR1B	ENSG00000188191	1.456090888016815	[89]	[83,242,91]	9	hSpCas9	negative selection	2154094
711463	711486	7	+	26627737	HCT116	viability after 15 days	GGCTCTCGTCCTCCTCCGAGGGG	PRKAR1B	ENSG00000188191	-0.08863724759746905	[142]	[105,118,10]	-1	hSpCas9	negative selection	2154095
579361	579384	7	-	26627737	HCT116	viability after 18 days	CGACAGAGTCCCTGGAGAAGTGG	PRKAR1B	ENSG00000188191	0.29911226947703273	[827]	[450,522,501]	2	hSpCas9	negative selection	2236187
596264	596287	7	-	26627737	HCT116	viability after 18 days	TGGGTGACCAACATCAGCGAGGG	PRKAR1B	ENSG00000188191	-0.7590103925304225	[810]	[350,105,246]	-6	hSpCas9	negative selection	2236195
677278	677301	7	-	26627737	HCT116	viability after 18 days	AACCATGACTGCGCTGGCCAAGG	PRKAR1B	ENSG00000188191	0.8049033448535978	[596]	[601,606,286]	6	hSpCas9	negative selection	2236272
680579	680602	7	-	26627737	HCT116	viability after 18 days	TGCCGAGGTGTACACCGAGGAGG	PRKAR1B	ENSG00000188191	-0.336755489529445	[282]	[276,21,27]	-3	hSpCas9	negative selection	2236276
711337	711360	7	+	26627737	HCT116	viability after 18 days	GCTTCTCGAAGTGCTCCCGGAGG	PRKAR1B	ENSG00000188191	1.480582678973649	[89]	[67,196,92]	9	hSpCas9	negative selection	2236409
711463	711486	7	+	26627737	HCT116	viability after 18 days	GGCTCTCGTCCTCCTCCGAGGGG	PRKAR1B	ENSG00000188191	-0.5298876905240892	[142]	[5,121,8]	-5	hSpCas9	negative selection	2236410
643504	643527	7	-	25494202	A375	resistance to PLX-4720 (puromycin)	GGTCTCGAACTCCCAACCTCTGG	PRKAR1B	ENSG00000188191	-0.16266902606406886	[97,288]	[29,46]	0	dCas9-VP64	positive selection	2385199
713301	713324	7	-	25494202	A375	resistance to PLX-4720 (puromycin)	GGAGGACCCCGGGGGTAGACAGG	PRKAR1B	ENSG00000188191	-0.2689422674099415	[44,124]	[5,25]	-1	dCas9-VP64	positive selection	2404728
713368	713391	7	-	25494202	A375	resistance to PLX-4720 (puromycin)	GGCAGGTGAGTGCAGGACCCGGG	PRKAR1B	ENSG00000188191	-0.2368075730102942	[100,70]	[11,19]	-1	dCas9-VP64	positive selection	2404729
713279	713302	7	-	25494202	A375	resistance to PLX-4720 (puromycin)	GTGAGTGTGCACAGGGAGGCAGG	PRKAR1B	ENSG00000188191	0.9613536213660702	[9,33]	[16,0]	4	dCas9-VP64	positive selection	2404730
713034	713057	7	-	25494202	A375	resistance to PLX-4720 (puromycin)	AGGTGGGAAAGAATTTAGGAGGG	PRKAR1B	ENSG00000188191	1.6028676393591381	[208,49]	[117,50]	6	dCas9-VP64	positive selection	2404731
713110	713133	7	-	25494202	A375	resistance to PLX-4720 (puromycin)	CAGGGCTGGGCTTGTGGGTTAGG	PRKAR1B	ENSG00000188191	0.8935592750031903	[149,22]	[63,2]	3	dCas9-VP64	positive selection	2404732
713058	713081	7	+	25494202	A375	resistance to PLX-4720 (puromycin)	TCTTGGGGATCCAGAGGTCACGG	PRKAR1B	ENSG00000188191	-0.37999831291447206	[38,157]	[6,25]	-2	dCas9-VP64	positive selection	2404733
688155	688178	7	+	25494202	A375	resistance to PLX-4720 (puromycin)	CTTTGGGAGGCCAAGGCGGGCGG	PRKAR1B	ENSG00000188191	0.09588317305989913	[114,12]	[10,18]	0	dCas9-VP64	positive selection	2411158
709398	709421	7	+	25494202	A375	resistance to PLX-4720 (puromycin)	AGTCTCGCTGTCGCCCAGGCTAG	PRKAR1B	ENSG00000188191	0.8346262078071658	[10,1]	[2,1]	3	dCas9-VP64	positive selection	2416319
684884	684907	7	+	25494202	A375	resistance to PLX-4720 (puromycin)	ACACACACACACACACACAGAGG	PRKAR1B	ENSG00000188191	0.19128589643959537	[429,108]	[111,17]	0	dCas9-VP64	positive selection	2424250
712669	712692	7	-	25494202	A375	resistance to PLX-4720 (puromycin)	GCGATGGCCTGAACCTGCGCCGG	PRKAR1B	ENSG00000188191	4.950524162702313	[0,5]	[7,44]	9	dCas9-VP64	positive selection	2431015
712694	712717	7	-	25494202	A375	resistance to PLX-4720 (puromycin)	GCGGCGACAGCGGGGGGTCCTGG	PRKAR1B	ENSG00000188191	2.6354690308790287	[42,6]	[56,7]	8	dCas9-VP64	positive selection	2431016
712600	712623	7	-	25494202	A375	resistance to PLX-4720 (puromycin)	TTGGGGGCCCCGCGGGGAGGCGG	PRKAR1B	ENSG00000188191	2.031310703030214	[4,4]	[0,8]	7	dCas9-VP64	positive selection	2431017
726527	726550	7	+	25494202	A375	resistance to PLX-4720 (puromycin)	AGGCAGGCTGGCGGGGGTTCCGG	PRKAR1B	ENSG00000188191	-0.5696338173797031	[38,16]	[2,3]	-3	dCas9-VP64	positive selection	2448992
726546	726569	7	-	25494202	A375	resistance to PLX-4720 (puromycin)	CCGCTGTCCCCCTCTGTCGCCGG	PRKAR1B	ENSG00000188191	0.5809874246933808	[61,139]	[11,55]	2	dCas9-VP64	positive selection	2448993
726584	726607	7	+	25494202	A375	resistance to PLX-4720 (puromycin)	GCACAGGCCCACGTGCGCACCGG	PRKAR1B	ENSG00000188191	0.6545537104672453	[148,11]	[35,16]	3	dCas9-VP64	positive selection	2448994
637321	637344	7	+	25494202	A375	resistance to PLX-4720 (puromycin)	GCGGGAGAATCGCTTGAACCAGG	PRKAR1B	ENSG00000188191	-0.7872021050505377	[82,16]	[7,2]	-4	dCas9-VP64	positive selection	2464281
721419	721442	7	+	25494202	A375	resistance to PLX-4720 (puromycin)	CAGGTGGATCACCTGAAGTCAGG	PRKAR1B	ENSG00000188191	-1.080501538256204	[504,81]	[37,20]	-6	dCas9-VP64	positive selection	2472807
643504	643527	7	-	25494202	A375	resistance to PLX-4720 (zeocin)	GGTCTCGAACTCCCAACCTCTGG	PRKAR1B	ENSG00000188191	0.7537551994741627	[30,51]	[21,22]	5	dCas9-VP64	positive selection	2480454
713301	713324	7	-	25494202	A375	resistance to PLX-4720 (zeocin)	GGAGGACCCCGGGGGTAGACAGG	PRKAR1B	ENSG00000188191	1.0148560857255278	[61,40]	[17,48]	6	dCas9-VP64	positive selection	2499983
713368	713391	7	-	25494202	A375	resistance to PLX-4720 (zeocin)	GGCAGGTGAGTGCAGGACCCGGG	PRKAR1B	ENSG00000188191	0.570650595167117	[80,47]	[48,13]	4	dCas9-VP64	positive selection	2499984
713279	713302	7	-	25494202	A375	resistance to PLX-4720 (zeocin)	GTGAGTGTGCACAGGGAGGCAGG	PRKAR1B	ENSG00000188191	-0.23185834829912877	[25,61]	[8,13]	-2	dCas9-VP64	positive selection	2499985
713034	713057	7	-	25494202	A375	resistance to PLX-4720 (zeocin)	AGGTGGGAAAGAATTTAGGAGGG	PRKAR1B	ENSG00000188191	-0.13465025507763825	[77,150]	[30,35]	-1	dCas9-VP64	positive selection	2499986
713110	713133	7	-	25494202	A375	resistance to PLX-4720 (zeocin)	CAGGGCTGGGCTTGTGGGTTAGG	PRKAR1B	ENSG00000188191	-1.0413811159213089	[299,58]	[44,12]	-8	dCas9-VP64	positive selection	2499987
713058	713081	7	+	25494202	A375	resistance to PLX-4720 (zeocin)	TCTTGGGGATCCAGAGGTCACGG	PRKAR1B	ENSG00000188191	-0.8214129774345503	[211,173]	[33,36]	-7	dCas9-VP64	positive selection	2499988
688155	688178	7	+	25494202	A375	resistance to PLX-4720 (zeocin)	CTTTGGGAGGCCAAGGCGGGCGG	PRKAR1B	ENSG00000188191	3.077269363618506	[19,18]	[13,93]	9	dCas9-VP64	positive selection	2506413
709398	709421	7	+	25494202	A375	resistance to PLX-4720 (zeocin)	AGTCTCGCTGTCGCCCAGGCTAG	PRKAR1B	ENSG00000188191	-1.711674582430177	[43,184]	[8,12]	-9	dCas9-VP64	positive selection	2511574
684884	684907	7	+	25494202	A375	resistance to PLX-4720 (zeocin)	ACACACACACACACACACAGAGG	PRKAR1B	ENSG00000188191	-0.29192793722986554	[278,490]	[95,106]	-3	dCas9-VP64	positive selection	2519505
712669	712692	7	-	25494202	A375	resistance to PLX-4720 (zeocin)	GCGATGGCCTGAACCTGCGCCGG	PRKAR1B	ENSG00000188191	-0.7897395605636304	[25,83]	[8,9]	-7	dCas9-VP64	positive selection	2526270
712694	712717	7	-	25494202	A375	resistance to PLX-4720 (zeocin)	GCGGCGACAGCGGGGGGTCCTGG	PRKAR1B	ENSG00000188191	5.446680886808908	[95,114]	[80,2849]	9	dCas9-VP64	positive selection	2526271
712600	712623	7	-	25494202	A375	resistance to PLX-4720 (zeocin)	TTGGGGGCCCCGCGGGGAGGCGG	PRKAR1B	ENSG00000188191	-0.001324444003050651	[8,35]	[3,9]	0	dCas9-VP64	positive selection	2526272
726527	726550	7	+	25494202	A375	resistance to PLX-4720 (zeocin)	AGGCAGGCTGGCGGGGGTTCCGG	PRKAR1B	ENSG00000188191	0.5161644455232026	[9,11]	[2,5]	4	dCas9-VP64	positive selection	2544247
726546	726569	7	-	25494202	A375	resistance to PLX-4720 (zeocin)	CCGCTGTCCCCCTCTGTCGCCGG	PRKAR1B	ENSG00000188191	0.3325503910102581	[213,174]	[124,37]	2	dCas9-VP64	positive selection	2544248
726584	726607	7	+	25494202	A375	resistance to PLX-4720 (zeocin)	GCACAGGCCCACGTGCGCACCGG	PRKAR1B	ENSG00000188191	0.01607726296271575	[125,68]	[40,23]	0	dCas9-VP64	positive selection	2544249
637321	637344	7	+	25494202	A375	resistance to PLX-4720 (zeocin)	GCGGGAGAATCGCTTGAACCAGG	PRKAR1B	ENSG00000188191	-0.42856361530074616	[34,35]	[8,6]	-4	dCas9-VP64	positive selection	2559536
721419	721442	7	+	25494202	A375	resistance to PLX-4720 (zeocin)	CAGGTGGATCACCTGAAGTCAGG	PRKAR1B	ENSG00000188191	0.09148827261213754	[58,380]	[33,114]	0	dCas9-VP64	positive selection	2568062
680582	680605	7	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GAGTGCCGAGGTGTACACCGAGG	PRKAR1B	ENSG00000188191	0.20817312378963623	[2,3]	[3,2]	4	hSpCas9	positive selection	3013645
680678	680701	7	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCAAAAGTCAAACTCACAGTCGG	PRKAR1B	ENSG00000188191	-0.18481635168778968	[4,4]	[5,1]	-3	hSpCas9	positive selection	3013646
711338	711361	7	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCTTCTCGAAGTGCTCCCGGAGG	PRKAR1B	ENSG00000188191	-0.36616262353478035	[3,2]	[0,2]	-5	hSpCas9	positive selection	3013647
711464	711487	7	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GGCTCTCGTCCTCCTCCGAGGGG	PRKAR1B	ENSG00000188191	0.3648029658569431	[3,3]	[4,3]	7	hSpCas9	positive selection	3013648
680582	680605	7	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GAGTGCCGAGGTGTACACCGAGG	PRKAR1B	ENSG00000188191	0.49259988571293734	[2,2]	[2,2]	8	hSpCas9	positive selection	3081503
680678	680701	7	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCAAAAGTCAAACTCACAGTCGG	PRKAR1B	ENSG00000188191	0.22682039838318635	[4,4]	[4,3]	4	hSpCas9	positive selection	3081504
711338	711361	7	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCTTCTCGAAGTGCTCCCGGAGG	PRKAR1B	ENSG00000188191	0.030290112476205673	[3,3]	[2,2]	0	hSpCas9	positive selection	3081505
711464	711487	7	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GGCTCTCGTCCTCCTCCGAGGGG	PRKAR1B	ENSG00000188191	0.07142073036096026	[3,3]	[3,1]	1	hSpCas9	positive selection	3081506
680559	680582		-	24336571	A375	resistance to PLX after 7 days	AGGACGCCGTGTCCTACGTCAGG	PRKAR1B	ENSG00000188191	0.24775388732412262	[12,17]	[17,18]	7	hSpCas9	positive selection	3137769
680600	680623		+	24336571	A375	resistance to PLX after 7 days	CACTCACGCCTCCTCGCCGGCGG	PRKAR1B	ENSG00000188191	0.16630678102982677	[18,16]	[19,20]	5	hSpCas9	positive selection	3137770
677284	677307		-	24336571	A375	resistance to PLX after 7 days	CTACAAAACCATGACTGCGCTGG	PRKAR1B	ENSG00000188191	0.19573213524845245	[6,5]	[7,6]	6	hSpCas9	positive selection	3137772
677245	677268		-	24336571	A375	resistance to PLX after 7 days	GAACGTGCTCTTCGCTCACCTGG	PRKAR1B	ENSG00000188191	-0.027482246857803316	[35,36]	[36,34]	0	hSpCas9	positive selection	3137773
680559	680582		-	24336571	A375	resistance to PLX after 14 days	AGGACGCCGTGTCCTACGTCAGG	PRKAR1B	ENSG00000188191	-0.778918467963367	[17,18]	[3,5]	-8	hSpCas9	positive selection	3195562
680600	680623		+	24336571	A375	resistance to PLX after 14 days	CACTCACGCCTCCTCGCCGGCGG	PRKAR1B	ENSG00000188191	0.13048041376996855	[23,12]	[11,6]	1	hSpCas9	positive selection	3195563
677284	677307		-	24336571	A375	resistance to PLX after 14 days	CTACAAAACCATGACTGCGCTGG	PRKAR1B	ENSG00000188191	0.9241674175896196	[5,7]	[5,5]	7	hSpCas9	positive selection	3195565
677245	677268		-	24336571	A375	resistance to PLX after 14 days	GAACGTGCTCTTCGCTCACCTGG	PRKAR1B	ENSG00000188191	0.5122725511420991	[32,37]	[23,22]	5	hSpCas9	positive selection	3195566
680559	680582		-	24336571	A375	viability after 7 days	AGGACGCCGTGTCCTACGTCAGG	PRKAR1B	ENSG00000188191	0.53522617839879	[10]	[12,17]	7	hSpCas9	negative selection	3253355
680600	680623		+	24336571	A375	viability after 7 days	CACTCACGCCTCCTCGCCGGCGG	PRKAR1B	ENSG00000188191	-0.01541924948702933	[19]	[18,16]	0	hSpCas9	negative selection	3253356
677284	677307		-	24336571	A375	viability after 7 days	CTACAAAACCATGACTGCGCTGG	PRKAR1B	ENSG00000188191	-0.9486990012551785	[13]	[6,5]	-8	hSpCas9	negative selection	3253358
677245	677268		-	24336571	A375	viability after 7 days	GAACGTGCTCTTCGCTCACCTGG	PRKAR1B	ENSG00000188191	0.4104841889938591	[28]	[35,36]	6	hSpCas9	negative selection	3253359
680559	680582		-	24336571	A375	viability after 14 days	AGGACGCCGTGTCCTACGTCAGG	PRKAR1B	ENSG00000188191	0.8200267348548532	[10]	[17,18]	9	hSpCas9	negative selection	3311148
680600	680623		+	24336571	A375	viability after 14 days	CACTCACGCCTCCTCGCCGGCGG	PRKAR1B	ENSG00000188191	0.030605610204974654	[19]	[23,12]	0	hSpCas9	negative selection	3311149
677284	677307		-	24336571	A375	viability after 14 days	CTACAAAACCATGACTGCGCTGG	PRKAR1B	ENSG00000188191	-0.8776921955775681	[13]	[5,7]	-8	hSpCas9	negative selection	3311151
677245	677268		-	24336571	A375	viability after 14 days	GAACGTGCTCTTCGCTCACCTGG	PRKAR1B	ENSG00000188191	0.3831416884180443	[28]	[32,37]	5	hSpCas9	negative selection	3311152
677245	677268	7	-	27383988	293T	resistance to West Nile virus (flavivirus)	GAACGTGCTCTTCGCTCACCTGG	PRKAR1B	ENSG00000188191	-1.0047686339243442	[306,306]	[0,0]	-6	hSpCas9	positive selection	3387470
680582	680605	7	-	26780180	HT29	viability (Avana library 4 designs)	GAGTGCCGAGGTGTACACCGAGG	PRKAR1B	ENSG00000188191	1.04872796814793	[]	[]	4	hSpCas9	negative selection	3451832
680678	680701	7	-	26780180	HT29	viability (Avana library 4 designs)	GCAAAAGTCAAACTCACAGTCGG	PRKAR1B	ENSG00000188191	-0.0276044648789464	[]	[]	0	hSpCas9	negative selection	3451833
711337	711360	7	+	26780180	HT29	viability (Avana library 4 designs)	GCTTCTCGAAGTGCTCCCGGAGG	PRKAR1B	ENSG00000188191	2.27959518819014	[]	[]	7	hSpCas9	negative selection	3451834
711463	711486	7	+	26780180	HT29	viability (Avana library 4 designs)	GGCTCTCGTCCTCCTCCGAGGGG	PRKAR1B	ENSG00000188191	1.57890109418219	[]	[]	6	hSpCas9	negative selection	3451835
711337	711360	7	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCTTCTCGAAGTGCTCCCGGAGG	PRKAR1B	ENSG00000188191	0.763451107194366	[]	[]	1	hSpCas9	negative selection	3547916
680678	680701	7	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCAAAAGTCAAACTCACAGTCGG	PRKAR1B	ENSG00000188191	-1.56744957354039	[]	[]	-2	hSpCas9	negative selection	3547917
680582	680605	7	-	26780180	A375	viability (Avana lentiCRISPRv2)	GAGTGCCGAGGTGTACACCGAGG	PRKAR1B	ENSG00000188191	1.06355894378057	[]	[]	1	hSpCas9	negative selection	3547918
711463	711486	7	+	26780180	A375	viability (Avana lentiCRISPRv2)	GGCTCTCGTCCTCCTCCGAGGGG	PRKAR1B	ENSG00000188191	3.84156875507642	[]	[]	6	hSpCas9	negative selection	3547919
711418	711441	7	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCAGCTGCACGGGATCCAGCAGG	PRKAR1B	ENSG00000188191	-0.366211594693465	[]	[]	0	hSpCas9	negative selection	3547920
711349	711372	7	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCTCCCGGAGGAACTTCATGGGG	PRKAR1B	ENSG00000188191	2.67248971274039	[]	[]	4	hSpCas9	negative selection	3547921
711337	711360	7	+	26780180	A375	viability (Avana lentiGuide)	GCTTCTCGAAGTGCTCCCGGAGG	PRKAR1B	ENSG00000188191	19.4044139259954	[]	[]	8	hSpCas9	negative selection	3656575
680678	680701	7	-	26780180	A375	viability (Avana lentiGuide)	GCAAAAGTCAAACTCACAGTCGG	PRKAR1B	ENSG00000188191	-2.8634173613604	[]	[]	-5	hSpCas9	negative selection	3656576
680582	680605	7	-	26780180	A375	viability (Avana lentiGuide)	GAGTGCCGAGGTGTACACCGAGG	PRKAR1B	ENSG00000188191	2.84927020873343	[]	[]	3	hSpCas9	negative selection	3656577
711463	711486	7	+	26780180	A375	viability (Avana lentiGuide)	GGCTCTCGTCCTCCTCCGAGGGG	PRKAR1B	ENSG00000188191	10.093551449159	[]	[]	7	hSpCas9	negative selection	3656578
711418	711441	7	-	26780180	A375	viability (Avana lentiGuide)	GCAGCTGCACGGGATCCAGCAGG	PRKAR1B	ENSG00000188191	3.6223016544277	[]	[]	3	hSpCas9	negative selection	3656579
711349	711372	7	+	26780180	A375	viability (Avana lentiGuide)	GCTCCCGGAGGAACTTCATGGGG	PRKAR1B	ENSG00000188191	1.2836198314035	[]	[]	1	hSpCas9	negative selection	3656580
711337	711360	7	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCTTCTCGAAGTGCTCCCGGAGG	PRKAR1B	ENSG00000188191	-0.19368252734893557	[4]	[3,2]	-3	hSpCas9	positive selection	3765182
680678	680701	7	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCAAAAGTCAAACTCACAGTCGG	PRKAR1B	ENSG00000188191	-0.17776796316541363	[5]	[4,4]	-3	hSpCas9	positive selection	3765183
680582	680605	7	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GAGTGCCGAGGTGTACACCGAGG	PRKAR1B	ENSG00000188191	0.19776394348166423	[3]	[4,4]	5	hSpCas9	positive selection	3765184
711463	711486	7	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGCTCTCGTCCTCCTCCGAGGGG	PRKAR1B	ENSG00000188191	0.1561651240686418	[5]	[5,5]	4	hSpCas9	positive selection	3765185
711418	711441	7	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCAGCTGCACGGGATCCAGCAGG	PRKAR1B	ENSG00000188191	-0.10217432231051055	[4]	[4,3]	-2	hSpCas9	positive selection	3765186
711349	711372	7	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCTCCCGGAGGAACTTCATGGGG	PRKAR1B	ENSG00000188191	0.13072580532627417	[5]	[6,5]	3	hSpCas9	positive selection	3765187
711337	711360	7	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCTTCTCGAAGTGCTCCCGGAGG	PRKAR1B	ENSG00000188191	-0.30672491309747163	[4]	[2,3]	-4	hSpCas9	positive selection	3873789
680678	680701	7	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCAAAAGTCAAACTCACAGTCGG	PRKAR1B	ENSG00000188191	0.04210456215144276	[6]	[5,6]	0	hSpCas9	positive selection	3873790
680582	680605	7	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GAGTGCCGAGGTGTACACCGAGG	PRKAR1B	ENSG00000188191	-0.22456672550165346	[5]	[2,4]	-3	hSpCas9	positive selection	3873791
711463	711486	7	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGCTCTCGTCCTCCTCCGAGGGG	PRKAR1B	ENSG00000188191	-0.47838022332322905	[5]	[3,2]	-6	hSpCas9	positive selection	3873792
711418	711441	7	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCAGCTGCACGGGATCCAGCAGG	PRKAR1B	ENSG00000188191	-0.13347621288453804	[5]	[3,4]	-2	hSpCas9	positive selection	3873793
711349	711372	7	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCTCCCGGAGGAACTTCATGGGG	PRKAR1B	ENSG00000188191	0.032259805546505455	[6]	[5,5]	0	hSpCas9	positive selection	3873794
680559	680582	7	-	26780180	A375	viability	AGGACGCCGTGTCCTACGTCAGG	PRKAR1B	ENSG00000188191	1.40735916400071	[]	[]	7	hSpCas9	negative selection	3984243
680600	680623	7	+	26780180	A375	viability	CACTCACGCCTCCTCGCCGGCGG	PRKAR1B	ENSG00000188191	1.07713778053519	[]	[]	5	hSpCas9	negative selection	3984244
677284	677307	7	-	26780180	A375	viability	CTACAAAACCATGACTGCGCTGG	PRKAR1B	ENSG00000188191	1.70692442442867	[]	[]	9	hSpCas9	negative selection	3984245
677245	677268	7	-	26780180	A375	viability	GAACGTGCTCTTCGCTCACCTGG	PRKAR1B	ENSG00000188191	0.76862619587466	[]	[]	3	hSpCas9	negative selection	3984246
680559	680582	7	-	26780180	HT29	viability (GeCKOv2 library)	AGGACGCCGTGTCCTACGTCAGG	PRKAR1B	ENSG00000188191	1.96025167255768	[]	[]	9	hSpCas9	negative selection	4092209
680600	680623	7	+	26780180	HT29	viability (GeCKOv2 library)	CACTCACGCCTCCTCGCCGGCGG	PRKAR1B	ENSG00000188191	1.12021670627455	[]	[]	5	hSpCas9	negative selection	4092210
677284	677307	7	-	26780180	HT29	viability (GeCKOv2 library)	CTACAAAACCATGACTGCGCTGG	PRKAR1B	ENSG00000188191	1.42458019113699	[]	[]	7	hSpCas9	negative selection	4092211
677245	677268	7	-	26780180	HT29	viability (GeCKOv2 library)	GAACGTGCTCTTCGCTCACCTGG	PRKAR1B	ENSG00000188191	1.47324838379565	[]	[]	7	hSpCas9	negative selection	4092212
680559	680582	7	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	AGGACGCCGTGTCCTACGTCAGG	PRKAR1B	ENSG00000188191	-0.057109343994956374	[3]	[2,2]	-1	hSpCas9	positive selection	4162924
680600	680623	7	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CACTCACGCCTCCTCGCCGGCGG	PRKAR1B	ENSG00000188191	0.07891376245882942	[4]	[2,3]	2	hSpCas9	positive selection	4162925
677284	677307	7	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CTACAAAACCATGACTGCGCTGG	PRKAR1B	ENSG00000188191	0.0821533151281249	[2]	[0,2]	2	hSpCas9	positive selection	4162927
677245	677268	7	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GAACGTGCTCTTCGCTCACCTGG	PRKAR1B	ENSG00000188191	0.1811272525277337	[4]	[2,4]	4	hSpCas9	positive selection	4162928
680559	680582	7	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	AGGACGCCGTGTCCTACGTCAGG	PRKAR1B	ENSG00000188191	0.3847478613366388	[3]	[1,3,4,0]	3	hSpCas9	positive selection	4226946
680600	680623	7	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CACTCACGCCTCCTCGCCGGCGG	PRKAR1B	ENSG00000188191	0.38235997935144345	[4]	[2,4,5,0]	3	hSpCas9	positive selection	4226947
677284	677307	7	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CTACAAAACCATGACTGCGCTGG	PRKAR1B	ENSG00000188191	0.3888580933782331	[1]	[0,3,0,0]	3	hSpCas9	positive selection	4226949
677245	677268	7	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GAACGTGCTCTTCGCTCACCTGG	PRKAR1B	ENSG00000188191	0.18390479991998193	[4]	[4,4,2,0]	1	hSpCas9	positive selection	4226950
680600	680623	7	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CACTCACGCCTCCTCGCCGGCGG	PRKAR1B	ENSG00000188191	0.1901378344632811	[3]	[3,2]	4	hSpCas9	positive selection	4292159
677284	677307	7	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CTACAAAACCATGACTGCGCTGG	PRKAR1B	ENSG00000188191	0.12362279617489424	[2]	[2,0]	2	hSpCas9	positive selection	4292160
680559	680582	7	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AGGACGCCGTGTCCTACGTCAGG	PRKAR1B	ENSG00000188191	-0.23144722838106244	[3]	[3,1]	-5	hSpCas9	positive selection	4292161
677245	677268	7	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GAACGTGCTCTTCGCTCACCTGG	PRKAR1B	ENSG00000188191	0.4867903844195409	[3]	[3,3]	8	hSpCas9	positive selection	4356417
596283	596305	7	-	27760321	OCIAML3	viability	GTGTACGTGAACGGAGAGTGGG	PRKAR1B	ENSG00000188191	0.09685965115242735	[373,385]	[307,333]	1	hSpCas9	negative selection	4430581
680555	680577	7	-	27760321	OCIAML3	viability	GCCGTGTCCTACGTCAGGAAGG	PRKAR1B	ENSG00000188191	0.43848193122113877	[614,468]	[503,655]	5	hSpCas9	negative selection	4430582
680582	680604	7	-	27760321	OCIAML3	viability	AGTGCCGAGGTGTACACCGAGG	PRKAR1B	ENSG00000188191	0.26717921133626676	[514,463]	[405,530]	3	hSpCas9	negative selection	4430583
680619	680641	7	+	27760321	OCIAML3	viability	GCGGCGGGCCTTCACCACAGGG	PRKAR1B	ENSG00000188191	0.5155628546796082	[767,659]	[620,1023]	6	hSpCas9	negative selection	4430584
596283	596305	7	-	27760321	OCIAML2	viability	GTGTACGTGAACGGAGAGTGGG	PRKAR1B	ENSG00000188191	-0.21025644896462875	[373,385]	[234,308]	-3	hSpCas9	negative selection	4514044
680555	680577	7	-	27760321	OCIAML2	viability	GCCGTGTCCTACGTCAGGAAGG	PRKAR1B	ENSG00000188191	0.43527556135198786	[614,468]	[466,747]	6	hSpCas9	negative selection	4514045
680582	680604	7	-	27760321	OCIAML2	viability	AGTGCCGAGGTGTACACCGAGG	PRKAR1B	ENSG00000188191	0.20121283977954532	[514,463]	[358,580]	2	hSpCas9	negative selection	4514046
680619	680641	7	+	27760321	OCIAML2	viability	GCGGCGGGCCTTCACCACAGGG	PRKAR1B	ENSG00000188191	0.0528687938841248	[767,659]	[558,647]	0	hSpCas9	negative selection	4514047
596283	596305	7	-	27760321	MV411	viability	GTGTACGTGAACGGAGAGTGGG	PRKAR1B	ENSG00000188191	0.5964630010041378	[373,385]	[489,216]	4	hSpCas9	negative selection	4597507
680555	680577	7	-	27760321	MV411	viability	GCCGTGTCCTACGTCAGGAAGG	PRKAR1B	ENSG00000188191	0.6248388656320764	[614,468]	[364,820]	4	hSpCas9	negative selection	4597508
680582	680604	7	-	27760321	MV411	viability	AGTGCCGAGGTGTACACCGAGG	PRKAR1B	ENSG00000188191	0.2803320256112637	[514,463]	[285,550]	2	hSpCas9	negative selection	4597509
680619	680641	7	+	27760321	MV411	viability	GCGGCGGGCCTTCACCACAGGG	PRKAR1B	ENSG00000188191	0.12376808306745635	[767,659]	[359,739]	0	hSpCas9	negative selection	4597510
596283	596305	7	-	27760321	HL60	viability	GTGTACGTGAACGGAGAGTGGG	PRKAR1B	ENSG00000188191	-0.49008802041238847	[373,385]	[172,273]	-5	hSpCas9	negative selection	4680970
680555	680577	7	-	27760321	HL60	viability	GCCGTGTCCTACGTCAGGAAGG	PRKAR1B	ENSG00000188191	0.21639316639603356	[614,468]	[506,513]	2	hSpCas9	negative selection	4680971
680582	680604	7	-	27760321	HL60	viability	AGTGCCGAGGTGTACACCGAGG	PRKAR1B	ENSG00000188191	0.36310101998428423	[514,463]	[688,327]	4	hSpCas9	negative selection	4680972
680619	680641	7	+	27760321	HL60	viability	GCGGCGGGCCTTCACCACAGGG	PRKAR1B	ENSG00000188191	0.2189976137723173	[767,659]	[622,733]	2	hSpCas9	negative selection	4680973
596283	596305	7	-	27760321	HT1080	viability	GTGTACGTGAACGGAGAGTGGG	PRKAR1B	ENSG00000188191	-0.29242260343936793	[385,300]	[105,117]	-1	hSpCas9	negative selection	4764433
680555	680577	7	-	27760321	HT1080	viability	GCCGTGTCCTACGTCAGGAAGG	PRKAR1B	ENSG00000188191	0.6906818514059914	[468,365]	[319,211]	3	hSpCas9	negative selection	4764434
680582	680604	7	-	27760321	HT1080	viability	AGTGCCGAGGTGTACACCGAGG	PRKAR1B	ENSG00000188191	-0.28678492709344505	[463,361]	[131,137]	-1	hSpCas9	negative selection	4764435
680619	680641	7	+	27760321	HT1080	viability	GCGGCGGGCCTTCACCACAGGG	PRKAR1B	ENSG00000188191	1.0536545869001852	[659,514]	[365,616]	6	hSpCas9	negative selection	4764436
596283	596305	7	-	27760321	HT29	viability after 7 days	GTGTACGTGAACGGAGAGTGGG	PRKAR1B	ENSG00000188191	-0.022345520002058583	[385,300]	[452,435,417]	0	hSpCas9	negative selection	4847896
680555	680577	7	-	27760321	HT29	viability after 7 days	GCCGTGTCCTACGTCAGGAAGG	PRKAR1B	ENSG00000188191	0.740953929419486	[468,365]	[874,1140,677]	9	hSpCas9	negative selection	4847897
680582	680604	7	-	27760321	HT29	viability after 7 days	AGTGCCGAGGTGTACACCGAGG	PRKAR1B	ENSG00000188191	0.1612962938770946	[463,361]	[650,521,614]	2	hSpCas9	negative selection	4847898
680619	680641	7	+	27760321	HT29	viability after 7 days	GCGGCGGGCCTTCACCACAGGG	PRKAR1B	ENSG00000188191	0.49401772248585396	[659,514]	[1115,848,1226]	7	hSpCas9	negative selection	4847899
596283	596305	7	-	27760321	HT29	viability after 25 days	GTGTACGTGAACGGAGAGTGGG	PRKAR1B	ENSG00000188191	-0.16233475689431232	[385,300]	[267,437,350]	-2	hSpCas9	negative selection	4931359
680555	680577	7	-	27760321	HT29	viability after 25 days	GCCGTGTCCTACGTCAGGAAGG	PRKAR1B	ENSG00000188191	0.730032278423853	[468,365]	[831,543,1017]	8	hSpCas9	negative selection	4931360
680582	680604	7	-	27760321	HT29	viability after 25 days	AGTGCCGAGGTGTACACCGAGG	PRKAR1B	ENSG00000188191	0.4561017968754631	[463,361]	[453,417,1131]	5	hSpCas9	negative selection	4931361
680619	680641	7	+	27760321	HT29	viability after 25 days	GCGGCGGGCCTTCACCACAGGG	PRKAR1B	ENSG00000188191	0.45515958374683585	[659,514]	[716,1003,1066]	5	hSpCas9	negative selection	4931362
596283	596305	7	-	27760321	HT29	viability after 22 days	GTGTACGTGAACGGAGAGTGGG	PRKAR1B	ENSG00000188191	-0.02918140558097919	[385,300]	[294,581,291]	0	hSpCas9	negative selection	5014822
680555	680577	7	-	27760321	HT29	viability after 22 days	GCCGTGTCCTACGTCAGGAAGG	PRKAR1B	ENSG00000188191	0.8965232161518462	[468,365]	[881,691,1123]	9	hSpCas9	negative selection	5014823
680582	680604	7	-	27760321	HT29	viability after 22 days	AGTGCCGAGGTGTACACCGAGG	PRKAR1B	ENSG00000188191	0.8955856012759669	[463,361]	[1120,679,856]	9	hSpCas9	negative selection	5014824
680619	680641	7	+	27760321	HT29	viability after 22 days	GCGGCGGGCCTTCACCACAGGG	PRKAR1B	ENSG00000188191	0.7480134259658071	[659,514]	[1302,923,1190]	8	hSpCas9	negative selection	5014825
596283	596305	7	-	27760321	HT29	viability after 19 days	GTGTACGTGAACGGAGAGTGGG	PRKAR1B	ENSG00000188191	0.08058378313926459	[385,300]	[320,605,312]	0	hSpCas9	negative selection	5098285
680555	680577	7	-	27760321	HT29	viability after 19 days	GCCGTGTCCTACGTCAGGAAGG	PRKAR1B	ENSG00000188191	0.7542800508222468	[468,365]	[822,640,947]	7	hSpCas9	negative selection	5098286
680582	680604	7	-	27760321	HT29	viability after 19 days	AGTGCCGAGGTGTACACCGAGG	PRKAR1B	ENSG00000188191	0.4865782919533745	[463,361]	[667,479,830]	5	hSpCas9	negative selection	5098287
680619	680641	7	+	27760321	HT29	viability after 19 days	GCGGCGGGCCTTCACCACAGGG	PRKAR1B	ENSG00000188191	0.6163436350842733	[659,514]	[1323,762,1032]	6	hSpCas9	negative selection	5098288
596283	596305	7	-	27760321	HT29	viability after 16 days	GTGTACGTGAACGGAGAGTGGG	PRKAR1B	ENSG00000188191	0.02809459398053498	[385,300]	[304,631,223]	0	hSpCas9	negative selection	5181748
680555	680577	7	-	27760321	HT29	viability after 16 days	GCCGTGTCCTACGTCAGGAAGG	PRKAR1B	ENSG00000188191	0.7593860867591417	[468,365]	[862,781,733]	8	hSpCas9	negative selection	5181749
680582	680604	7	-	27760321	HT29	viability after 16 days	AGTGCCGAGGTGTACACCGAGG	PRKAR1B	ENSG00000188191	0.2762215979999812	[463,361]	[605,749,321]	3	hSpCas9	negative selection	5181750
680619	680641	7	+	27760321	HT29	viability after 16 days	GCGGCGGGCCTTCACCACAGGG	PRKAR1B	ENSG00000188191	0.9305067696799838	[659,514]	[1208,943,1608]	9	hSpCas9	negative selection	5181751
596283	596305	7	-	27760321	HT29	viability after 13 days	GTGTACGTGAACGGAGAGTGGG	PRKAR1B	ENSG00000188191	-0.6001054246726418	[385,300]	[316,251,221]	-6	hSpCas9	negative selection	5265211
680555	680577	7	-	27760321	HT29	viability after 13 days	GCCGTGTCCTACGTCAGGAAGG	PRKAR1B	ENSG00000188191	0.7969370124854755	[468,365]	[677,1009,836]	9	hSpCas9	negative selection	5265212
680582	680604	7	-	27760321	HT29	viability after 13 days	AGTGCCGAGGTGTACACCGAGG	PRKAR1B	ENSG00000188191	0.5251980862709564	[463,361]	[828,735,513]	6	hSpCas9	negative selection	5265213
680619	680641	7	+	27760321	HT29	viability after 13 days	GCGGCGGGCCTTCACCACAGGG	PRKAR1B	ENSG00000188191	0.7821637955410106	[659,514]	[1271,1177,1071]	8	hSpCas9	negative selection	5265214
596283	596305	7	-	27760321	HT29	viability after 10 days	GTGTACGTGAACGGAGAGTGGG	PRKAR1B	ENSG00000188191	-0.15698809758548232	[385,300]	[407,316,425]	-2	hSpCas9	negative selection	5348674
680555	680577	7	-	27760321	HT29	viability after 10 days	GCCGTGTCCTACGTCAGGAAGG	PRKAR1B	ENSG00000188191	0.45271731534216486	[468,365]	[735,840,569]	6	hSpCas9	negative selection	5348675
680582	680604	7	-	27760321	HT29	viability after 10 days	AGTGCCGAGGTGTACACCGAGG	PRKAR1B	ENSG00000188191	0.0014826985342240584	[463,361]	[528,581,440]	0	hSpCas9	negative selection	5348676
680619	680641	7	+	27760321	HT29	viability after 10 days	GCGGCGGGCCTTCACCACAGGG	PRKAR1B	ENSG00000188191	0.7851148352287178	[659,514]	[1216,1207,1362]	9	hSpCas9	negative selection	5348677
596283	596305	7	-	27760321	MOLM13	viability	GTGTACGTGAACGGAGAGTGGG	PRKAR1B	ENSG00000188191	-2.147220571898094	[373,385]	[46,49]	-8	hSpCas9	negative selection	5432137
680555	680577	7	-	27760321	MOLM13	viability	GCCGTGTCCTACGTCAGGAAGG	PRKAR1B	ENSG00000188191	0.09175699302799895	[614,468]	[385,269]	0	hSpCas9	negative selection	5432138
680582	680604	7	-	27760321	MOLM13	viability	AGTGCCGAGGTGTACACCGAGG	PRKAR1B	ENSG00000188191	0.8617386494555731	[514,463]	[529,476]	6	hSpCas9	negative selection	5432139
680619	680641	7	+	27760321	MOLM13	viability	GCGGCGGGCCTTCACCACAGGG	PRKAR1B	ENSG00000188191	1.33729566848187	[767,659]	[827,1173]	8	hSpCas9	negative selection	5432140
711997	712020	7	+	27661255	K562	viability	GGCTGGGGCGGCCTCTGCACAGG	PRKAR1B	ENSG00000188191	0.2342663982734614	[225,207]	[241,171]	7	dCas9-KRAB	negative selection	5504133
712073	712096	7	+	27661255	K562	viability	GTGCGGGAGAACAAATGCGGCGG	PRKAR1B	ENSG00000188191	0.21137203292138113	[772,1010]	[854,791]	7	dCas9-KRAB	negative selection	5504134
712095	712118	7	+	27661255	K562	viability	GCCGCGCAGCGAAGTCACCATGG	PRKAR1B	ENSG00000188191	0.3624888349186277	[439,542]	[558,454]	9	dCas9-KRAB	negative selection	5504135
712249	712272	7	+	27661255	K562	viability	GCGCCGGCGAGGACCCTCCCGGG	PRKAR1B	ENSG00000188191	0.09328894138368216	[214,239]	[186,198]	3	dCas9-KRAB	negative selection	5504136
712403	712426	7	+	27661255	K562	viability	GCCCCGCGTACCTGGATGCGCGG	PRKAR1B	ENSG00000188191	0.17766610464527988	[314,326]	[271,304]	6	dCas9-KRAB	negative selection	5504137
712134	712157	7	-	27661255	K562	viability	GGGTCCTGCGCCCCGCGGTGCGG	PRKAR1B	ENSG00000188191	0.07204345424663054	[650,693]	[576,552]	2	dCas9-KRAB	negative selection	5504138
680600	680623	7	+	27260156	BXPC3	viability	CACTCACGCCTCCTCGCCGGCGG	PRKAR1B	ENSG00000188191	0.2557214239425789	[650]	[738,859,818,834]	5	hSpCas9	negative selection	5564619
677284	677307	7	-	27260156	BXPC3	viability	CTACAAAACCATGACTGCGCTGG	PRKAR1B	ENSG00000188191	-0.3975182879967052	[236]	[145,203,219,184]	-7	hSpCas9	negative selection	5564620
680559	680582	7	-	27260156	BXPC3	viability	AGGACGCCGTGTCCTACGTCAGG	PRKAR1B	ENSG00000188191	0.2262869570013707	[804]	[821,1063,1076,982]	5	hSpCas9	negative selection	5564621
677245	677268	7	-	27260156	BXPC3	viability	GAACGTGCTCTTCGCTCACCTGG	PRKAR1B	ENSG00000188191	0.2852416019464582	[562]	[667,705,783,712]	6	hSpCas9	negative selection	5628877
680600	680623	7	+	27260156	A673	viability	CACTCACGCCTCCTCGCCGGCGG	PRKAR1B	ENSG00000188191	0.2745109509807937	[650]	[1018,759,1028,986]	6	hSpCas9	negative selection	5685870
677284	677307	7	-	27260156	A673	viability	CTACAAAACCATGACTGCGCTGG	PRKAR1B	ENSG00000188191	-0.2902681029115175	[236]	[280,226,201,225]	-6	hSpCas9	negative selection	5685871
680559	680582	7	-	27260156	A673	viability	AGGACGCCGTGTCCTACGTCAGG	PRKAR1B	ENSG00000188191	0.08788434073890217	[804]	[1244,1063,831,989]	2	hSpCas9	negative selection	5685872
677245	677268	7	-	27260156	A673	viability	GAACGTGCTCTTCGCTCACCTGG	PRKAR1B	ENSG00000188191	0.21887140774204178	[562]	[1052,703,587,837]	5	hSpCas9	negative selection	5750128
680600	680623	7	+	27260156	A375	viability	CACTCACGCCTCCTCGCCGGCGG	PRKAR1B	ENSG00000188191	-0.10363565983789147	[650]	[660,892,588,709]	-1	hSpCas9	negative selection	5807121
677284	677307	7	-	27260156	A375	viability	CTACAAAACCATGACTGCGCTGG	PRKAR1B	ENSG00000188191	-0.3630883827370863	[236]	[190,294,243,148]	-5	hSpCas9	negative selection	5807122
680559	680582	7	-	27260156	A375	viability	AGGACGCCGTGTCCTACGTCAGG	PRKAR1B	ENSG00000188191	0.38182359755219586	[804]	[1054,1160,1291,1360]	5	hSpCas9	negative selection	5807123
677245	677268	7	-	27260156	A375	viability	GAACGTGCTCTTCGCTCACCTGG	PRKAR1B	ENSG00000188191	0.520649040303359	[562]	[929,1017,952,885]	7	hSpCas9	negative selection	5871379
680600	680623	7	+	27260156	COLO741	viability	CACTCACGCCTCCTCGCCGGCGG	PRKAR1B	ENSG00000188191	0.1294515703094783	[650]	[884,1006,838]	2	hSpCas9	negative selection	5928372
677284	677307	7	-	27260156	COLO741	viability	CTACAAAACCATGACTGCGCTGG	PRKAR1B	ENSG00000188191	-0.179040926468373	[236]	[282,278,242]	-4	hSpCas9	negative selection	5928373
680559	680582	7	-	27260156	COLO741	viability	AGGACGCCGTGTCCTACGTCAGG	PRKAR1B	ENSG00000188191	0.16232020870600228	[804]	[1340,1137,998]	3	hSpCas9	negative selection	5928374
677245	677268	7	-	27260156	COLO741	viability	GAACGTGCTCTTCGCTCACCTGG	PRKAR1B	ENSG00000188191	0.38246291335695426	[562]	[815,949,1027]	7	hSpCas9	negative selection	5992630
680600	680623	7	+	27260156	CAL120	viability	CACTCACGCCTCCTCGCCGGCGG	PRKAR1B	ENSG00000188191	0.17807968344939318	[650]	[1042,1019,708]	2	hSpCas9	negative selection	6049623
677284	677307	7	-	27260156	CAL120	viability	CTACAAAACCATGACTGCGCTGG	PRKAR1B	ENSG00000188191	-0.2976158261361772	[236]	[250,263,206]	-4	hSpCas9	negative selection	6049624
680559	680582	7	-	27260156	CAL120	viability	AGGACGCCGTGTCCTACGTCAGG	PRKAR1B	ENSG00000188191	0.2629676014480392	[804]	[1228,1478,906]	4	hSpCas9	negative selection	6049625
677245	677268	7	-	27260156	CAL120	viability	GAACGTGCTCTTCGCTCACCTGG	PRKAR1B	ENSG00000188191	0.2558213659254831	[562]	[1033,896,611]	4	hSpCas9	negative selection	6113881
680600	680623	7	+	27260156	CADOES1	viability	CACTCACGCCTCCTCGCCGGCGG	PRKAR1B	ENSG00000188191	0.06582245169650902	[650]	[525,567,756,685]	1	hSpCas9	negative selection	6170874
677284	677307	7	-	27260156	CADOES1	viability	CTACAAAACCATGACTGCGCTGG	PRKAR1B	ENSG00000188191	-0.19380292182376424	[236]	[171,176,225,195]	-3	hSpCas9	negative selection	6170875
680559	680582	7	-	27260156	CADOES1	viability	AGGACGCCGTGTCCTACGTCAGG	PRKAR1B	ENSG00000188191	0.16452788937505647	[804]	[951,877,696,828]	3	hSpCas9	negative selection	6170876
677245	677268	7	-	27260156	CADOES1	viability	GAACGTGCTCTTCGCTCACCTGG	PRKAR1B	ENSG00000188191	0.46287104898070874	[562]	[954,673,742,505]	7	hSpCas9	negative selection	6235132
680600	680623	7	+	27260156	EWS502	viability	CACTCACGCCTCCTCGCCGGCGG	PRKAR1B	ENSG00000188191	0.33193793932053817	[650]	[892,844,683,1054]	6	hSpCas9	negative selection	6292125
677284	677307	7	-	27260156	EWS502	viability	CTACAAAACCATGACTGCGCTGG	PRKAR1B	ENSG00000188191	-0.02914172527534431	[236]	[241,158,283,306]	0	hSpCas9	negative selection	6292126
680559	680582	7	-	27260156	EWS502	viability	AGGACGCCGTGTCCTACGTCAGG	PRKAR1B	ENSG00000188191	0.20514274199841553	[804]	[1034,1031,818,1034]	3	hSpCas9	negative selection	6292127
677245	677268	7	-	27260156	EWS502	viability	GAACGTGCTCTTCGCTCACCTGG	PRKAR1B	ENSG00000188191	0.34263755301370014	[562]	[852,820,555,775]	6	hSpCas9	negative selection	6356383
680600	680623	7	+	27260156	EW8	viability	CACTCACGCCTCCTCGCCGGCGG	PRKAR1B	ENSG00000188191	0.26114837782419964	[650]	[719,716,564,546]	5	hSpCas9	negative selection	6413376
677284	677307	7	-	27260156	EW8	viability	CTACAAAACCATGACTGCGCTGG	PRKAR1B	ENSG00000188191	0.08033667572356451	[236]	[197,252,133,237]	1	hSpCas9	negative selection	6413377
680559	680582	7	-	27260156	EW8	viability	AGGACGCCGTGTCCTACGTCAGG	PRKAR1B	ENSG00000188191	0.02575757887211283	[804]	[735,783,547,614]	0	hSpCas9	negative selection	6413378
677245	677268	7	-	27260156	EW8	viability	GAACGTGCTCTTCGCTCACCTGG	PRKAR1B	ENSG00000188191	0.03348021064046741	[562]	[477,473,447,470]	0	hSpCas9	negative selection	6477634
680600	680623	7	+	27260156	CORL105	viability	CACTCACGCCTCCTCGCCGGCGG	PRKAR1B	ENSG00000188191	0.43388300961269044	[650]	[1178,901,1001,1037]	7	hSpCas9	negative selection	6534627
677284	677307	7	-	27260156	CORL105	viability	CTACAAAACCATGACTGCGCTGG	PRKAR1B	ENSG00000188191	-0.12037491375240994	[236]	[217,213,235,348]	-2	hSpCas9	negative selection	6534628
680559	680582	7	-	27260156	CORL105	viability	AGGACGCCGTGTCCTACGTCAGG	PRKAR1B	ENSG00000188191	0.12399338210669453	[804]	[1038,871,1211,1016]	2	hSpCas9	negative selection	6534629
677245	677268	7	-	27260156	CORL105	viability	GAACGTGCTCTTCGCTCACCTGG	PRKAR1B	ENSG00000188191	0.22357619633456632	[562]	[673,578,898,945]	4	hSpCas9	negative selection	6598885
680600	680623	7	+	27260156	HS294T	viability	CACTCACGCCTCCTCGCCGGCGG	PRKAR1B	ENSG00000188191	0.5477571430369076	[650]	[390,333,358,388]	7	hSpCas9	negative selection	6655878
677284	677307	7	-	27260156	HS294T	viability	CTACAAAACCATGACTGCGCTGG	PRKAR1B	ENSG00000188191	0.11801245523630244	[236]	[85,104,80,131]	1	hSpCas9	negative selection	6655879
680559	680582	7	-	27260156	HS294T	viability	AGGACGCCGTGTCCTACGTCAGG	PRKAR1B	ENSG00000188191	0.7719249873034352	[804]	[476,778,357,501]	8	hSpCas9	negative selection	6655880
677245	677268	7	-	27260156	HS294T	viability	GAACGTGCTCTTCGCTCACCTGG	PRKAR1B	ENSG00000188191	0.18985879101342562	[562]	[162,266,266,313]	2	hSpCas9	negative selection	6720136
680600	680623	7	+	27260156	HCC44	viability	CACTCACGCCTCCTCGCCGGCGG	PRKAR1B	ENSG00000188191	0.3324799214827643	[650]	[994,590,1394,856]	5	hSpCas9	negative selection	6777129
677284	677307	7	-	27260156	HCC44	viability	CTACAAAACCATGACTGCGCTGG	PRKAR1B	ENSG00000188191	-0.12296793270615902	[236]	[271,121,291,321]	-2	hSpCas9	negative selection	6777130
680559	680582	7	-	27260156	HCC44	viability	AGGACGCCGTGTCCTACGTCAGG	PRKAR1B	ENSG00000188191	0.22678430492667656	[804]	[1313,814,1081,1101]	3	hSpCas9	negative selection	6777131
677245	677268	7	-	27260156	HCC44	viability	GAACGTGCTCTTCGCTCACCTGG	PRKAR1B	ENSG00000188191	0.37309055254029555	[562]	[1027,597,936,799]	6	hSpCas9	negative selection	6841387
680600	680623	7	+	27260156	G402	viability	CACTCACGCCTCCTCGCCGGCGG	PRKAR1B	ENSG00000188191	0.0033889719929415807	[650]	[536,963,875,777]	0	hSpCas9	negative selection	6898380
677284	677307	7	-	27260156	G402	viability	CTACAAAACCATGACTGCGCTGG	PRKAR1B	ENSG00000188191	-0.1494170063263791	[236]	[524,187,104,257]	-2	hSpCas9	negative selection	6898381
680559	680582	7	-	27260156	G402	viability	AGGACGCCGTGTCCTACGTCAGG	PRKAR1B	ENSG00000188191	0.21879281263311412	[804]	[1153,864,1466,1070]	2	hSpCas9	negative selection	6898382
677245	677268	7	-	27260156	G402	viability	GAACGTGCTCTTCGCTCACCTGG	PRKAR1B	ENSG00000188191	0.392949461667203	[562]	[926,771,623,1259]	5	hSpCas9	negative selection	6962638
680600	680623	7	+	27260156	L33	viability	CACTCACGCCTCCTCGCCGGCGG	PRKAR1B	ENSG00000188191	0.4770786705242076	[650]	[916,387,611,787]	8	hSpCas9	negative selection	7019631
677284	677307	7	-	27260156	L33	viability	CTACAAAACCATGACTGCGCTGG	PRKAR1B	ENSG00000188191	0.2127975043830984	[236]	[348,87,193,224]	4	hSpCas9	negative selection	7019632
680559	680582	7	-	27260156	L33	viability	AGGACGCCGTGTCCTACGTCAGG	PRKAR1B	ENSG00000188191	-0.04452858763232137	[804]	[869,304,560,614]	-1	hSpCas9	negative selection	7019633
677245	677268	7	-	27260156	L33	viability	GAACGTGCTCTTCGCTCACCTGG	PRKAR1B	ENSG00000188191	0.2006235429462067	[562]	[599,246,506,580]	4	hSpCas9	negative selection	7083889
680600	680623	7	+	27260156	K562	viability	CACTCACGCCTCCTCGCCGGCGG	PRKAR1B	ENSG00000188191	0.785207463526555	[650]	[2148,552,1008,407]	8	hSpCas9	negative selection	7140882
677284	677307	7	-	27260156	K562	viability	CTACAAAACCATGACTGCGCTGG	PRKAR1B	ENSG00000188191	0.5521183913776884	[236]	[346,663,188,80]	7	hSpCas9	negative selection	7140883
680559	680582	7	-	27260156	K562	viability	AGGACGCCGTGTCCTACGTCAGG	PRKAR1B	ENSG00000188191	0.1293430480916382	[804]	[707,951,804,672]	1	hSpCas9	negative selection	7140884
677245	677268	7	-	27260156	K562	viability	GAACGTGCTCTTCGCTCACCTGG	PRKAR1B	ENSG00000188191	0.6855830510204657	[562]	[759,672,544,1177]	8	hSpCas9	negative selection	7205140
680600	680623	7	+	27260156	HT29	viability	CACTCACGCCTCCTCGCCGGCGG	PRKAR1B	ENSG00000188191	0.1509656437590553	[650]	[1011,808,942,762]	3	hSpCas9	negative selection	7262133
677284	677307	7	-	27260156	HT29	viability	CTACAAAACCATGACTGCGCTGG	PRKAR1B	ENSG00000188191	0.06342141386979383	[236]	[221,298,375,298]	1	hSpCas9	negative selection	7262134
680559	680582	7	-	27260156	HT29	viability	AGGACGCCGTGTCCTACGTCAGG	PRKAR1B	ENSG00000188191	0.15320866750443252	[804]	[1070,1000,959,1279]	3	hSpCas9	negative selection	7262135
677245	677268	7	-	27260156	HT29	viability	GAACGTGCTCTTCGCTCACCTGG	PRKAR1B	ENSG00000188191	0.4818269339735416	[562]	[1050,1099,847,849]	8	hSpCas9	negative selection	7326391
680600	680623	7	+	27260156	MHHES1	viability	CACTCACGCCTCCTCGCCGGCGG	PRKAR1B	ENSG00000188191	0.3560615642679966	[650]	[1172,995,822,804]	6	hSpCas9	negative selection	7383384
677284	677307	7	-	27260156	MHHES1	viability	CTACAAAACCATGACTGCGCTGG	PRKAR1B	ENSG00000188191	-0.0670292191669295	[236]	[342,178,268,230]	-1	hSpCas9	negative selection	7383385
680559	680582	7	-	27260156	MHHES1	viability	AGGACGCCGTGTCCTACGTCAGG	PRKAR1B	ENSG00000188191	0.2574555753017863	[804]	[1034,1221,1177,921]	5	hSpCas9	negative selection	7383386
677245	677268	7	-	27260156	MHHES1	viability	GAACGTGCTCTTCGCTCACCTGG	PRKAR1B	ENSG00000188191	0.3056145720123834	[562]	[1015,741,677,718]	5	hSpCas9	negative selection	7447642
680600	680623	7	+	27260156	MEWO	viability	CACTCACGCCTCCTCGCCGGCGG	PRKAR1B	ENSG00000188191	0.24024871633166434	[650]	[868,728,588]	5	hSpCas9	negative selection	7504635
677284	677307	7	-	27260156	MEWO	viability	CTACAAAACCATGACTGCGCTGG	PRKAR1B	ENSG00000188191	-0.16191110093577743	[236]	[321,97,198]	-4	hSpCas9	negative selection	7504636
680559	680582	7	-	27260156	MEWO	viability	AGGACGCCGTGTCCTACGTCAGG	PRKAR1B	ENSG00000188191	0.20786511904160243	[804]	[947,968,706]	4	hSpCas9	negative selection	7504637
677245	677268	7	-	27260156	MEWO	viability	GAACGTGCTCTTCGCTCACCTGG	PRKAR1B	ENSG00000188191	0.5065184190110115	[562]	[991,719,579]	8	hSpCas9	negative selection	7568893
680600	680623	7	+	27260156	LNCAPCLONEFGC	viability	CACTCACGCCTCCTCGCCGGCGG	PRKAR1B	ENSG00000188191	0.3247238640983532	[650]	[847,592,884,656]	5	hSpCas9	negative selection	7625886
677284	677307	7	-	27260156	LNCAPCLONEFGC	viability	CTACAAAACCATGACTGCGCTGG	PRKAR1B	ENSG00000188191	-0.132309532235521	[236]	[97,156,324,226]	-2	hSpCas9	negative selection	7625887
680559	680582	7	-	27260156	LNCAPCLONEFGC	viability	AGGACGCCGTGTCCTACGTCAGG	PRKAR1B	ENSG00000188191	0.3954939818493154	[804]	[1154,738,1161,820]	6	hSpCas9	negative selection	7625888
677245	677268	7	-	27260156	LNCAPCLONEFGC	viability	GAACGTGCTCTTCGCTCACCTGG	PRKAR1B	ENSG00000188191	0.5981010266513651	[562]	[870,693,881,659]	8	hSpCas9	negative selection	7690144
680600	680623	7	+	27260156	PANC0327	viability	CACTCACGCCTCCTCGCCGGCGG	PRKAR1B	ENSG00000188191	-0.13330554377529363	[650]	[887,276,630,374]	-2	hSpCas9	negative selection	7747137
677284	677307	7	-	27260156	PANC0327	viability	CTACAAAACCATGACTGCGCTGG	PRKAR1B	ENSG00000188191	-0.5393961515192125	[236]	[120,193,100,154]	-6	hSpCas9	negative selection	7747138
680559	680582	7	-	27260156	PANC0327	viability	AGGACGCCGTGTCCTACGTCAGG	PRKAR1B	ENSG00000188191	0.2983415307406857	[804]	[806,1076,941,659]	4	hSpCas9	negative selection	7747139
677245	677268	7	-	27260156	PANC0327	viability	GAACGTGCTCTTCGCTCACCTGG	PRKAR1B	ENSG00000188191	0.5306923117220415	[562]	[950,1064,458,388]	7	hSpCas9	negative selection	7811395
680600	680623	7	+	27260156	NCIH2009	viability	CACTCACGCCTCCTCGCCGGCGG	PRKAR1B	ENSG00000188191	0.7685943857437415	[650]	[1684,1642,1342]	9	hSpCas9	negative selection	7868388
677284	677307	7	-	27260156	NCIH2009	viability	CTACAAAACCATGACTGCGCTGG	PRKAR1B	ENSG00000188191	0.4305139997596379	[236]	[485,439,419]	6	hSpCas9	negative selection	7868389
680559	680582	7	-	27260156	NCIH2009	viability	AGGACGCCGTGTCCTACGTCAGG	PRKAR1B	ENSG00000188191	0.40589835215063197	[804]	[2102,1216,1273]	5	hSpCas9	negative selection	7868390
677245	677268	7	-	27260156	NCIH2009	viability	GAACGTGCTCTTCGCTCACCTGG	PRKAR1B	ENSG00000188191	0.35325448443623686	[562]	[1393,933,762]	5	hSpCas9	negative selection	7932646
680600	680623	7	+	27260156	NCIH1373	viability	CACTCACGCCTCCTCGCCGGCGG	PRKAR1B	ENSG00000188191	0.11820211055947827	[650]	[928,628,1082,141]	1	hSpCas9	negative selection	7989639
677284	677307	7	-	27260156	NCIH1373	viability	CTACAAAACCATGACTGCGCTGG	PRKAR1B	ENSG00000188191	0.34798275044078897	[236]	[430,240,409,75]	3	hSpCas9	negative selection	7989640
680559	680582	7	-	27260156	NCIH1373	viability	AGGACGCCGTGTCCTACGTCAGG	PRKAR1B	ENSG00000188191	0.6474213616762138	[804]	[1758,1150,1248,415]	6	hSpCas9	negative selection	7989641
677245	677268	7	-	27260156	NCIH1373	viability	GAACGTGCTCTTCGCTCACCTGG	PRKAR1B	ENSG00000188191	0.6226818802298806	[562]	[969,711,1026,318]	6	hSpCas9	negative selection	8053897
680600	680623	7	+	27260156	PATU8902	viability	CACTCACGCCTCCTCGCCGGCGG	PRKAR1B	ENSG00000188191	0.21519634796529596	[650]	[1173,624,1127,1278]	2	hSpCas9	negative selection	8110890
677284	677307	7	-	27260156	PATU8902	viability	CTACAAAACCATGACTGCGCTGG	PRKAR1B	ENSG00000188191	0.11476458434990466	[236]	[275,352,278,564]	1	hSpCas9	negative selection	8110891
680559	680582	7	-	27260156	PATU8902	viability	AGGACGCCGTGTCCTACGTCAGG	PRKAR1B	ENSG00000188191	0.9053121724846162	[804]	[1291,2566,2055,2543]	8	hSpCas9	negative selection	8110892
677245	677268	7	-	27260156	PATU8902	viability	GAACGTGCTCTTCGCTCACCTGG	PRKAR1B	ENSG00000188191	0.808544374814231	[562]	[1216,947,891,2710]	8	hSpCas9	negative selection	8175148
680600	680623	7	+	27260156	PANC1	viability	CACTCACGCCTCCTCGCCGGCGG	PRKAR1B	ENSG00000188191	0.10487356905167267	[650]	[557,689,564,600]	1	hSpCas9	negative selection	8232141
677284	677307	7	-	27260156	PANC1	viability	CTACAAAACCATGACTGCGCTGG	PRKAR1B	ENSG00000188191	0.39343521253824254	[236]	[201,367,295,227]	6	hSpCas9	negative selection	8232142
680559	680582	7	-	27260156	PANC1	viability	AGGACGCCGTGTCCTACGTCAGG	PRKAR1B	ENSG00000188191	0.2626969956616706	[804]	[797,1100,855,637]	4	hSpCas9	negative selection	8232143
677245	677268	7	-	27260156	PANC1	viability	GAACGTGCTCTTCGCTCACCTGG	PRKAR1B	ENSG00000188191	0.37756653939258134	[562]	[649,834,530,541]	6	hSpCas9	negative selection	8296399
680600	680623	7	+	27260156	PANC0813	viability	CACTCACGCCTCCTCGCCGGCGG	PRKAR1B	ENSG00000188191	0.45005538503108855	[650]	[857,1361,865,1070]	7	hSpCas9	negative selection	8353392
677284	677307	7	-	27260156	PANC0813	viability	CTACAAAACCATGACTGCGCTGG	PRKAR1B	ENSG00000188191	0.334630125429231	[236]	[330,238,523,310]	5	hSpCas9	negative selection	8353393
680559	680582	7	-	27260156	PANC0813	viability	AGGACGCCGTGTCCTACGTCAGG	PRKAR1B	ENSG00000188191	0.266623363877467	[804]	[1279,978,1445,872]	4	hSpCas9	negative selection	8353394
677245	677268	7	-	27260156	PANC0813	viability	GAACGTGCTCTTCGCTCACCTGG	PRKAR1B	ENSG00000188191	0.30011926706724523	[562]	[898,852,749,763]	5	hSpCas9	negative selection	8417650
680600	680623	7	+	27260156	RDES	viability	CACTCACGCCTCCTCGCCGGCGG	PRKAR1B	ENSG00000188191	0.05262214352101413	[650]	[573,664,866,1082]	0	hSpCas9	negative selection	8474643
677284	677307	7	-	27260156	RDES	viability	CTACAAAACCATGACTGCGCTGG	PRKAR1B	ENSG00000188191	-0.35992889435015196	[236]	[242,140,242,216]	-6	hSpCas9	negative selection	8474644
680559	680582	7	-	27260156	RDES	viability	AGGACGCCGTGTCCTACGTCAGG	PRKAR1B	ENSG00000188191	0.3935055801715269	[804]	[870,1063,1434,1619]	6	hSpCas9	negative selection	8474645
677245	677268	7	-	27260156	RDES	viability	GAACGTGCTCTTCGCTCACCTGG	PRKAR1B	ENSG00000188191	0.5592542175592986	[562]	[696,915,1072,1204]	8	hSpCas9	negative selection	8538901
680600	680623	7	+	27260156	PC3	viability	CACTCACGCCTCCTCGCCGGCGG	PRKAR1B	ENSG00000188191	0.23530394752890682	[650]	[540,842,1383,527]	5	hSpCas9	negative selection	8595894
677284	677307	7	-	27260156	PC3	viability	CTACAAAACCATGACTGCGCTGG	PRKAR1B	ENSG00000188191	-0.32385192326973966	[236]	[97,150,456,179]	-6	hSpCas9	negative selection	8595895
680559	680582	7	-	27260156	PC3	viability	AGGACGCCGTGTCCTACGTCAGG	PRKAR1B	ENSG00000188191	0.08346196048157983	[804]	[479,807,1281,1098]	2	hSpCas9	negative selection	8595896
677245	677268	7	-	27260156	PC3	viability	GAACGTGCTCTTCGCTCACCTGG	PRKAR1B	ENSG00000188191	0.3125314539486489	[562]	[419,495,1379,832]	6	hSpCas9	negative selection	8660152
680600	680623	7	+	27260156	PATU8988T	viability	CACTCACGCCTCCTCGCCGGCGG	PRKAR1B	ENSG00000188191	0.2704943748046502	[650]	[712,645,898,764]	4	hSpCas9	negative selection	8717145
677284	677307	7	-	27260156	PATU8988T	viability	CTACAAAACCATGACTGCGCTGG	PRKAR1B	ENSG00000188191	-0.05600884375262405	[236]	[130,335,186,239]	-1	hSpCas9	negative selection	8717146
680559	680582	7	-	27260156	PATU8988T	viability	AGGACGCCGTGTCCTACGTCAGG	PRKAR1B	ENSG00000188191	0.22533730903729576	[804]	[865,1007,933,831]	4	hSpCas9	negative selection	8717147
677245	677268	7	-	27260156	PATU8988T	viability	GAACGTGCTCTTCGCTCACCTGG	PRKAR1B	ENSG00000188191	0.21965878173114367	[562]	[664,716,538,620]	4	hSpCas9	negative selection	8781403
680600	680623	7	+	27260156	T47D	viability	CACTCACGCCTCCTCGCCGGCGG	PRKAR1B	ENSG00000188191	-0.16446139343982452	[650]	[692,592,663,766]	-4	hSpCas9	negative selection	8838396
677284	677307	7	-	27260156	T47D	viability	CTACAAAACCATGACTGCGCTGG	PRKAR1B	ENSG00000188191	-0.10314534384325835	[236]	[229,275,247,272]	-2	hSpCas9	negative selection	8838397
680559	680582	7	-	27260156	T47D	viability	AGGACGCCGTGTCCTACGTCAGG	PRKAR1B	ENSG00000188191	0.11526247770445552	[804]	[968,920,1033,1150]	2	hSpCas9	negative selection	8838398
677245	677268	7	-	27260156	T47D	viability	GAACGTGCTCTTCGCTCACCTGG	PRKAR1B	ENSG00000188191	0.22150745317032133	[562]	[775,717,806,760]	5	hSpCas9	negative selection	8902654
680600	680623	7	+	27260156	SU8686	viability	CACTCACGCCTCCTCGCCGGCGG	PRKAR1B	ENSG00000188191	0.26227328492584845	[650]	[684,748,852,827]	4	hSpCas9	negative selection	8959647
677284	677307	7	-	27260156	SU8686	viability	CTACAAAACCATGACTGCGCTGG	PRKAR1B	ENSG00000188191	0.24746936407904097	[236]	[277,241,312,287]	4	hSpCas9	negative selection	8959648
680559	680582	7	-	27260156	SU8686	viability	AGGACGCCGTGTCCTACGTCAGG	PRKAR1B	ENSG00000188191	0.18640652981016348	[804]	[822,763,1151,924]	3	hSpCas9	negative selection	8959649
677245	677268	7	-	27260156	SU8686	viability	GAACGTGCTCTTCGCTCACCTGG	PRKAR1B	ENSG00000188191	0.2541154315409919	[562]	[667,689,568,735]	4	hSpCas9	negative selection	9023905
680600	680623	7	+	27260156	SKES1	viability	CACTCACGCCTCCTCGCCGGCGG	PRKAR1B	ENSG00000188191	0.31657008761966954	[650]	[936,910,662,753]	6	hSpCas9	negative selection	9080898
677284	677307	7	-	27260156	SKES1	viability	CTACAAAACCATGACTGCGCTGG	PRKAR1B	ENSG00000188191	-0.1937954609905037	[236]	[194,236,251,148]	-4	hSpCas9	negative selection	9080899
680559	680582	7	-	27260156	SKES1	viability	AGGACGCCGTGTCCTACGTCAGG	PRKAR1B	ENSG00000188191	0.10757499103382573	[804]	[821,917,845,865]	2	hSpCas9	negative selection	9080900
677245	677268	7	-	27260156	SKES1	viability	GAACGTGCTCTTCGCTCACCTGG	PRKAR1B	ENSG00000188191	0.4381544393103257	[562]	[822,737,855,637]	8	hSpCas9	negative selection	9145156
680600	680623	7	+	27260156	TOV112D	viability	CACTCACGCCTCCTCGCCGGCGG	PRKAR1B	ENSG00000188191	0.2478555134105589	[650]	[780,959,702,699]	5	hSpCas9	negative selection	9202149
677284	677307	7	-	27260156	TOV112D	viability	CTACAAAACCATGACTGCGCTGG	PRKAR1B	ENSG00000188191	0.20684331136928658	[236]	[352,183,199,340]	4	hSpCas9	negative selection	9202150
680559	680582	7	-	27260156	TOV112D	viability	AGGACGCCGTGTCCTACGTCAGG	PRKAR1B	ENSG00000188191	0.11507731336424032	[804]	[1126,726,650,968]	2	hSpCas9	negative selection	9202151
677245	677268	7	-	27260156	TOV112D	viability	GAACGTGCTCTTCGCTCACCTGG	PRKAR1B	ENSG00000188191	0.3689829445018271	[562]	[685,1180,550,604]	7	hSpCas9	negative selection	9266407
680600	680623	7	+	27260156	TC71	viability	CACTCACGCCTCCTCGCCGGCGG	PRKAR1B	ENSG00000188191	0.2670570309952347	[650]	[862,831,792,873]	6	hSpCas9	negative selection	9323400
677284	677307	7	-	27260156	TC71	viability	CTACAAAACCATGACTGCGCTGG	PRKAR1B	ENSG00000188191	-0.17327004554968206	[236]	[219,224,221,234]	-4	hSpCas9	negative selection	9323401
680559	680582	7	-	27260156	TC71	viability	AGGACGCCGTGTCCTACGTCAGG	PRKAR1B	ENSG00000188191	-0.016951943798292124	[804]	[839,863,759,956]	0	hSpCas9	negative selection	9323402
677245	677268	7	-	27260156	TC71	viability	GAACGTGCTCTTCGCTCACCTGG	PRKAR1B	ENSG00000188191	0.22016237209362038	[562]	[617,785,673,738]	5	hSpCas9	negative selection	9387658
680600	680623	7	+	27260156	TC32	viability	CACTCACGCCTCCTCGCCGGCGG	PRKAR1B	ENSG00000188191	-0.01688110254926789	[650]	[604,315,913,719]	0	hSpCas9	negative selection	9444651
677284	677307	7	-	27260156	TC32	viability	CTACAAAACCATGACTGCGCTGG	PRKAR1B	ENSG00000188191	-0.1351898926447117	[236]	[292,105,273,160]	-2	hSpCas9	negative selection	9444652
680559	680582	7	-	27260156	TC32	viability	AGGACGCCGTGTCCTACGTCAGG	PRKAR1B	ENSG00000188191	0.19542731666063307	[804]	[723,590,1071,1205]	3	hSpCas9	negative selection	9444653
677245	677268	7	-	27260156	TC32	viability	GAACGTGCTCTTCGCTCACCTGG	PRKAR1B	ENSG00000188191	0.46760267537999867	[562]	[828,509,714,905]	7	hSpCas9	negative selection	9508909
579361	579384	7	-	27869803	HPAFII	viability after 27 days	CGACAGAGTCCCTGGAGAAGTGG	PRKAR1B	ENSG00000188191	0.947107356347788	[486]	[527,464,NaN]	7	hSpCas9	negative selection	9599938
596264	596287	7	-	27869803	HPAFII	viability after 27 days	TGGGTGACCAACATCAGCGAGGG	PRKAR1B	ENSG00000188191	-0.8474602176859486	[597]	[243,116,NaN]	-5	hSpCas9	negative selection	9599946
677278	677301	7	-	27869803	HPAFII	viability after 27 days	AACCATGACTGCGCTGGCCAAGG	PRKAR1B	ENSG00000188191	0.8530585111093922	[436]	[426,404,NaN]	7	hSpCas9	negative selection	9600023
680579	680602	7	-	27869803	HPAFII	viability after 27 days	TGCCGAGGTGTACACCGAGGAGG	PRKAR1B	ENSG00000188191	-1.590527071589201	[137]	[22,24,NaN]	-7	hSpCas9	negative selection	9600027
711337	711360	7	+	27869803	HPAFII	viability after 27 days	GCTTCTCGAAGTGCTCCCGGAGG	PRKAR1B	ENSG00000188191	0.1698491000854151	[175]	[162,54,NaN]	1	hSpCas9	negative selection	9600160
711463	711486	7	+	27869803	HPAFII	viability after 27 days	GGCTCTCGTCCTCCTCCGAGGGG	PRKAR1B	ENSG00000188191	-0.7715215770298771	[97]	[51,11,NaN]	-5	hSpCas9	negative selection	9600161
579361	579384	7	-	27869803	HPAFII	viability after 15 days	CGACAGAGTCCCTGGAGAAGTGG	PRKAR1B	ENSG00000188191	0.34213894191124317	[486]	[890,521,NaN]	4	hSpCas9	negative selection	9682387
596264	596287	7	-	27869803	HPAFII	viability after 15 days	TGGGTGACCAACATCAGCGAGGG	PRKAR1B	ENSG00000188191	-0.5584417990224615	[597]	[695,274,NaN]	-6	hSpCas9	negative selection	9682395
677278	677301	7	-	27869803	HPAFII	viability after 15 days	AACCATGACTGCGCTGGCCAAGG	PRKAR1B	ENSG00000188191	0.4980201453333426	[436]	[1023,438,NaN]	6	hSpCas9	negative selection	9682472
680579	680602	7	-	27869803	HPAFII	viability after 15 days	TGCCGAGGTGTACACCGAGGAGG	PRKAR1B	ENSG00000188191	-0.6642418593587613	[137]	[145,60,NaN]	-6	hSpCas9	negative selection	9682476
711337	711360	7	+	27869803	HPAFII	viability after 15 days	GCTTCTCGAAGTGCTCCCGGAGG	PRKAR1B	ENSG00000188191	0.5206887959534534	[175]	[435,168,NaN]	6	hSpCas9	negative selection	9682609
711463	711486	7	+	27869803	HPAFII	viability after 15 days	GGCTCTCGTCCTCCTCCGAGGGG	PRKAR1B	ENSG00000188191	-0.891215175001359	[97]	[86,37,NaN]	-7	hSpCas9	negative selection	9682610
579361	579384	7	-	27869803	ASPC1	viability after 36 days	CGACAGAGTCCCTGGAGAAGTGG	PRKAR1B	ENSG00000188191	0.32256120185561143	[1532]	[987,524,552]	3	hSpCas9	negative selection	9764836
596264	596287	7	-	27869803	ASPC1	viability after 36 days	TGGGTGACCAACATCAGCGAGGG	PRKAR1B	ENSG00000188191	-0.8042670430807771	[1100]	[361,140,180]	-7	hSpCas9	negative selection	9764844
677278	677301	7	-	27869803	ASPC1	viability after 36 days	AACCATGACTGCGCTGGCCAAGG	PRKAR1B	ENSG00000188191	0.09201703606512379	[1220]	[716,577,166]	0	hSpCas9	negative selection	9764921
680579	680602	7	-	27869803	ASPC1	viability after 36 days	TGCCGAGGTGTACACCGAGGAGG	PRKAR1B	ENSG00000188191	-0.3023729905335336	[329]	[68,78,120]	-3	hSpCas9	negative selection	9764925
711337	711360	7	+	27869803	ASPC1	viability after 36 days	GCTTCTCGAAGTGCTCCCGGAGG	PRKAR1B	ENSG00000188191	0.11448747506417101	[428]	[288,47,161]	1	hSpCas9	negative selection	9765058
711463	711486	7	+	27869803	ASPC1	viability after 36 days	GGCTCTCGTCCTCCTCCGAGGGG	PRKAR1B	ENSG00000188191	0.08298581596964016	[280]	[26,124,139]	0	hSpCas9	negative selection	9765059
579361	579384	7	-	27869803	PATU8988S	viability after 35 days	CGACAGAGTCCCTGGAGAAGTGG	PRKAR1B	ENSG00000188191	-0.16858031569579346	[1389]	[534,460,NaN]	-2	hSpCas9	negative selection	9847285
596264	596287	7	-	27869803	PATU8988S	viability after 35 days	TGGGTGACCAACATCAGCGAGGG	PRKAR1B	ENSG00000188191	-0.02884466883403547	[874]	[314,375,NaN]	0	hSpCas9	negative selection	9847293
677278	677301	7	-	27869803	PATU8988S	viability after 35 days	AACCATGACTGCGCTGGCCAAGG	PRKAR1B	ENSG00000188191	-0.18535796134821814	[1277]	[520,383,NaN]	-2	hSpCas9	negative selection	9847370
680579	680602	7	-	27869803	PATU8988S	viability after 35 days	TGCCGAGGTGTACACCGAGGAGG	PRKAR1B	ENSG00000188191	-0.08532647099369584	[227]	[109,62,NaN]	-1	hSpCas9	negative selection	9847374
711337	711360	7	+	27869803	PATU8988S	viability after 35 days	GCTTCTCGAAGTGCTCCCGGAGG	PRKAR1B	ENSG00000188191	1.376484965349321	[371]	[385,391,NaN]	9	hSpCas9	negative selection	9847507
711463	711486	7	+	27869803	PATU8988S	viability after 35 days	GGCTCTCGTCCTCCTCCGAGGGG	PRKAR1B	ENSG00000188191	-0.3469278862188234	[250]	[71,86,NaN]	-4	hSpCas9	negative selection	9847508
579361	579384	7	-	27869803	PATU8988S	viability after 31 days	CGACAGAGTCCCTGGAGAAGTGG	PRKAR1B	ENSG00000188191	-0.4986326487213696	[1389]	[430,342,NaN]	-5	hSpCas9	negative selection	9929734
596264	596287	7	-	27869803	PATU8988S	viability after 31 days	TGGGTGACCAACATCAGCGAGGG	PRKAR1B	ENSG00000188191	-0.0016524758402817197	[874]	[256,464,NaN]	0	hSpCas9	negative selection	9929742
677278	677301	7	-	27869803	PATU8988S	viability after 31 days	AACCATGACTGCGCTGGCCAAGG	PRKAR1B	ENSG00000188191	-0.2777448253827044	[1277]	[389,458,NaN]	-3	hSpCas9	negative selection	9929819
680579	680602	7	-	27869803	PATU8988S	viability after 31 days	TGCCGAGGTGTACACCGAGGAGG	PRKAR1B	ENSG00000188191	0.4988834601186577	[227]	[87,179,NaN]	6	hSpCas9	negative selection	9929823
711337	711360	7	+	27869803	PATU8988S	viability after 31 days	GCTTCTCGAAGTGCTCCCGGAGG	PRKAR1B	ENSG00000188191	0.5615127411164166	[371]	[177,270,NaN]	6	hSpCas9	negative selection	9929956
711463	711486	7	+	27869803	PATU8988S	viability after 31 days	GGCTCTCGTCCTCCTCCGAGGGG	PRKAR1B	ENSG00000188191	0.1816882815471984	[250]	[98,131,NaN]	2	hSpCas9	negative selection	9929957
579361	579384	7	-	27869803	HPAFII	viability after 35 days	CGACAGAGTCCCTGGAGAAGTGG	PRKAR1B	ENSG00000188191	0.6558391741605761	[486]	[315,469,NaN]	4	hSpCas9	negative selection	10012183
596264	596287	7	-	27869803	HPAFII	viability after 35 days	TGGGTGACCAACATCAGCGAGGG	PRKAR1B	ENSG00000188191	-1.4402207353480145	[597]	[175,38,NaN]	-6	hSpCas9	negative selection	10012191
677278	677301	7	-	27869803	HPAFII	viability after 35 days	AACCATGACTGCGCTGGCCAAGG	PRKAR1B	ENSG00000188191	0.8016372217262582	[436]	[331,445,NaN]	5	hSpCas9	negative selection	10012268
680579	680602	7	-	27869803	HPAFII	viability after 35 days	TGCCGAGGTGTACACCGAGGAGG	PRKAR1B	ENSG00000188191	-1.3812963781695875	[137]	[15,38,NaN]	-6	hSpCas9	negative selection	10012272
711337	711360	7	+	27869803	HPAFII	viability after 35 days	GCTTCTCGAAGTGCTCCCGGAGG	PRKAR1B	ENSG00000188191	0.2902656776242255	[175]	[139,73,NaN]	1	hSpCas9	negative selection	10012405
711463	711486	7	+	27869803	HPAFII	viability after 35 days	GGCTCTCGTCCTCCTCCGAGGGG	PRKAR1B	ENSG00000188191	-1.3889016411938804	[97]	[25,10,NaN]	-6	hSpCas9	negative selection	10012406
579361	579384	7	-	27869803	HPAFII	viability after 31 days	CGACAGAGTCCCTGGAGAAGTGG	PRKAR1B	ENSG00000188191	0.6974770608901096	[486]	[369,522,NaN]	5	hSpCas9	negative selection	10094632
596264	596287	7	-	27869803	HPAFII	viability after 31 days	TGGGTGACCAACATCAGCGAGGG	PRKAR1B	ENSG00000188191	-1.267100249474801	[597]	[193,79,NaN]	-6	hSpCas9	negative selection	10094640
677278	677301	7	-	27869803	HPAFII	viability after 31 days	AACCATGACTGCGCTGGCCAAGG	PRKAR1B	ENSG00000188191	0.5291670339527816	[436]	[273,440,NaN]	4	hSpCas9	negative selection	10094717
680579	680602	7	-	27869803	HPAFII	viability after 31 days	TGCCGAGGTGTACACCGAGGAGG	PRKAR1B	ENSG00000188191	-2.3309641200714175	[137]	[12,17,NaN]	-8	hSpCas9	negative selection	10094721
711337	711360	7	+	27869803	HPAFII	viability after 31 days	GCTTCTCGAAGTGCTCCCGGAGG	PRKAR1B	ENSG00000188191	0.008076438285082255	[175]	[128,66,NaN]	0	hSpCas9	negative selection	10094854
711463	711486	7	+	27869803	HPAFII	viability after 31 days	GGCTCTCGTCCTCCTCCGAGGGG	PRKAR1B	ENSG00000188191	-0.752643211439485	[97]	[46,16,NaN]	-5	hSpCas9	negative selection	10094855
711337	711360	7	+	28162770	P31FUJ	viability	GCTTCTCGAAGTGCTCCCGGAGG	PRKAR1B	ENSG00000188191	0.227927385557334	[201]	[277]	2	hSpCas9	negative selection	10217020
680700	680723	7	-	28162770	P31FUJ	viability	AAAACAGGCAGATTTTGGCGCGG	PRKAR1B	ENSG00000188191	1.0302322014194154	[249]	[599]	9	hSpCas9	negative selection	10217021
596264	596287	7	-	28162770	P31FUJ	viability	TGGGTGACCAACATCAGCGAGGG	PRKAR1B	ENSG00000188191	1.162921819807631	[140]	[370]	9	hSpCas9	negative selection	10217022
680582	680605	7	-	28162770	P31FUJ	viability	GAGTGCCGAGGTGTACACCGAGG	PRKAR1B	ENSG00000188191	0.2220997557424046	[115]	[158]	2	hSpCas9	negative selection	10217023
579345	579368	7	-	28162770	P31FUJ	viability	GAAGTGGGAGCGTCTGACCGTGG	PRKAR1B	ENSG00000188191	0.6416669135017625	[71]	[131]	7	hSpCas9	negative selection	10217024
579328	579351	7	+	28162770	P31FUJ	viability	GGGCTCCAGCGCATCCGCCACGG	PRKAR1B	ENSG00000188191	-0.22514863187094333	[187]	[188]	-2	hSpCas9	negative selection	10217025
551381	551404	7	+	28162770	P31FUJ	viability	GGACTCACCGAAGTAGTCAGAGG	PRKAR1B	ENSG00000188191	0.301887089825554	[291]	[422]	3	hSpCas9	negative selection	10217026
711457	711480	7	-	28162770	P31FUJ	viability	GGAGGAGGACGAGAGCCTGAAGG	PRKAR1B	ENSG00000188191	0.9027853893847967	[136]	[300]	9	hSpCas9	negative selection	10217027
711418	711441	7	-	28162770	P31FUJ	viability	GCAGCTGCACGGGATCCAGCAGG	PRKAR1B	ENSG00000188191	0.8983153478277589	[246]	[540]	8	hSpCas9	negative selection	10217028
711373	711396	7	+	28162770	P31FUJ	viability	GTTCGGGCTTGGAGATGCAGAGG	PRKAR1B	ENSG00000188191	0.3762959363293148	[572]	[873]	4	hSpCas9	negative selection	10217029
711337	711360	7	+	28162770	TF1	viability	GCTTCTCGAAGTGCTCCCGGAGG	PRKAR1B	ENSG00000188191	NaN	[NaN]	[205]	1	hSpCas9	negative selection	10386386
680700	680723	7	-	28162770	TF1	viability	AAAACAGGCAGATTTTGGCGCGG	PRKAR1B	ENSG00000188191	NaN	[NaN]	[283]	1	hSpCas9	negative selection	10386387
596264	596287	7	-	28162770	TF1	viability	TGGGTGACCAACATCAGCGAGGG	PRKAR1B	ENSG00000188191	NaN	[NaN]	[74]	1	hSpCas9	negative selection	10386388
680582	680605	7	-	28162770	TF1	viability	GAGTGCCGAGGTGTACACCGAGG	PRKAR1B	ENSG00000188191	NaN	[NaN]	[135]	1	hSpCas9	negative selection	10386389
579345	579368	7	-	28162770	TF1	viability	GAAGTGGGAGCGTCTGACCGTGG	PRKAR1B	ENSG00000188191	NaN	[NaN]	[44]	1	hSpCas9	negative selection	10386390
579328	579351	7	+	28162770	TF1	viability	GGGCTCCAGCGCATCCGCCACGG	PRKAR1B	ENSG00000188191	NaN	[NaN]	[140]	1	hSpCas9	negative selection	10386391
551381	551404	7	+	28162770	TF1	viability	GGACTCACCGAAGTAGTCAGAGG	PRKAR1B	ENSG00000188191	NaN	[NaN]	[461]	1	hSpCas9	negative selection	10386392
711457	711480	7	-	28162770	TF1	viability	GGAGGAGGACGAGAGCCTGAAGG	PRKAR1B	ENSG00000188191	NaN	[NaN]	[142]	1	hSpCas9	negative selection	10386393
711418	711441	7	-	28162770	TF1	viability	GCAGCTGCACGGGATCCAGCAGG	PRKAR1B	ENSG00000188191	NaN	[NaN]	[273]	1	hSpCas9	negative selection	10386394
711373	711396	7	+	28162770	TF1	viability	GTTCGGGCTTGGAGATGCAGAGG	PRKAR1B	ENSG00000188191	NaN	[NaN]	[455]	1	hSpCas9	negative selection	10386395
711337	711360	7	+	28162770	SKM1	viability	GCTTCTCGAAGTGCTCCCGGAGG	PRKAR1B	ENSG00000188191	-0.2370391973008492	[63]	[95]	-2	hSpCas9	negative selection	10555752
680700	680723	7	-	28162770	SKM1	viability	AAAACAGGCAGATTTTGGCGCGG	PRKAR1B	ENSG00000188191	0.6325641654434757	[80]	[221]	6	hSpCas9	negative selection	10555753
596264	596287	7	-	28162770	SKM1	viability	TGGGTGACCAACATCAGCGAGGG	PRKAR1B	ENSG00000188191	0.27110770636947595	[44]	[95]	2	hSpCas9	negative selection	10555754
680582	680605	7	-	28162770	SKM1	viability	GAGTGCCGAGGTGTACACCGAGG	PRKAR1B	ENSG00000188191	0.47345418550416585	[32]	[80]	4	hSpCas9	negative selection	10555755
579345	579368	7	-	28162770	SKM1	viability	GAAGTGGGAGCGTCTGACCGTGG	PRKAR1B	ENSG00000188191	0.5447806326496172	[18]	[48]	5	hSpCas9	negative selection	10555756
579328	579351	7	+	28162770	SKM1	viability	GGGCTCCAGCGCATCCGCCACGG	PRKAR1B	ENSG00000188191	-0.2521460896910577	[63]	[94]	-2	hSpCas9	negative selection	10555757
551381	551404	7	+	28162770	SKM1	viability	GGACTCACCGAAGTAGTCAGAGG	PRKAR1B	ENSG00000188191	-0.5171471164935845	[67]	[83]	-4	hSpCas9	negative selection	10555758
711457	711480	7	-	28162770	SKM1	viability	GGAGGAGGACGAGAGCCTGAAGG	PRKAR1B	ENSG00000188191	-0.5078931075939425	[36]	[45]	-4	hSpCas9	negative selection	10555759
711418	711441	7	-	28162770	SKM1	viability	GCAGCTGCACGGGATCCAGCAGG	PRKAR1B	ENSG00000188191	-0.5040316167033264	[72]	[90]	-4	hSpCas9	negative selection	10555760
711373	711396	7	+	28162770	SKM1	viability	GTTCGGGCTTGGAGATGCAGAGG	PRKAR1B	ENSG00000188191	-0.21431912080076576	[125]	[191]	-2	hSpCas9	negative selection	10555761
711337	711360	7	+	28162770	SKM1	viability	GCTTCTCGAAGTGCTCCCGGAGG	PRKAR1B	ENSG00000188191	-0.2370391973008492	[63]	[95]	-2	hSpCas9	negative selection	10725118
680700	680723	7	-	28162770	SKM1	viability	AAAACAGGCAGATTTTGGCGCGG	PRKAR1B	ENSG00000188191	0.6325641654434757	[80]	[221]	6	hSpCas9	negative selection	10725119
596264	596287	7	-	28162770	SKM1	viability	TGGGTGACCAACATCAGCGAGGG	PRKAR1B	ENSG00000188191	0.27110770636947595	[44]	[95]	2	hSpCas9	negative selection	10725120
680582	680605	7	-	28162770	SKM1	viability	GAGTGCCGAGGTGTACACCGAGG	PRKAR1B	ENSG00000188191	0.47345418550416585	[32]	[80]	4	hSpCas9	negative selection	10725121
579345	579368	7	-	28162770	SKM1	viability	GAAGTGGGAGCGTCTGACCGTGG	PRKAR1B	ENSG00000188191	0.5447806326496172	[18]	[48]	5	hSpCas9	negative selection	10725122
579328	579351	7	+	28162770	SKM1	viability	GGGCTCCAGCGCATCCGCCACGG	PRKAR1B	ENSG00000188191	-0.2521460896910577	[63]	[94]	-2	hSpCas9	negative selection	10725123
551381	551404	7	+	28162770	SKM1	viability	GGACTCACCGAAGTAGTCAGAGG	PRKAR1B	ENSG00000188191	-0.5171471164935845	[67]	[83]	-4	hSpCas9	negative selection	10725124
711457	711480	7	-	28162770	SKM1	viability	GGAGGAGGACGAGAGCCTGAAGG	PRKAR1B	ENSG00000188191	-0.5078931075939425	[36]	[45]	-4	hSpCas9	negative selection	10725125
711418	711441	7	-	28162770	SKM1	viability	GCAGCTGCACGGGATCCAGCAGG	PRKAR1B	ENSG00000188191	-0.5040316167033264	[72]	[90]	-4	hSpCas9	negative selection	10725126
711373	711396	7	+	28162770	SKM1	viability	GTTCGGGCTTGGAGATGCAGAGG	PRKAR1B	ENSG00000188191	-0.21431912080076576	[125]	[191]	-2	hSpCas9	negative selection	10725127
711337	711360	7	+	28162770	PL21	viability	GCTTCTCGAAGTGCTCCCGGAGG	PRKAR1B	ENSG00000188191	-0.08576925759706026	[177]	[72]	0	hSpCas9	negative selection	10894484
680700	680723	7	-	28162770	PL21	viability	AAAACAGGCAGATTTTGGCGCGG	PRKAR1B	ENSG00000188191	0.8615541756483496	[195]	[154]	7	hSpCas9	negative selection	10894485
596264	596287	7	-	28162770	PL21	viability	TGGGTGACCAACATCAGCGAGGG	PRKAR1B	ENSG00000188191	0.11025411097212512	[148]	[69]	1	hSpCas9	negative selection	10894486
680582	680605	7	-	28162770	PL21	viability	GAGTGCCGAGGTGTACACCGAGG	PRKAR1B	ENSG00000188191	-0.9638361206218057	[120]	[26]	-6	hSpCas9	negative selection	10894487
579345	579368	7	-	28162770	PL21	viability	GAAGTGGGAGCGTCTGACCGTGG	PRKAR1B	ENSG00000188191	0.9777471931528723	[55]	[47]	7	hSpCas9	negative selection	10894488
579328	579351	7	+	28162770	PL21	viability	GGGCTCCAGCGCATCCGCCACGG	PRKAR1B	ENSG00000188191	-0.47558835015501855	[245]	[76]	-3	hSpCas9	negative selection	10894489
551381	551404	7	+	28162770	PL21	viability	GGACTCACCGAAGTAGTCAGAGG	PRKAR1B	ENSG00000188191	-0.1721355651587213	[276]	[106]	-1	hSpCas9	negative selection	10894490
711457	711480	7	-	28162770	PL21	viability	GGAGGAGGACGAGAGCCTGAAGG	PRKAR1B	ENSG00000188191	0.4280915611676686	[110]	[64]	4	hSpCas9	negative selection	10894491
711418	711441	7	-	28162770	PL21	viability	GCAGCTGCACGGGATCCAGCAGG	PRKAR1B	ENSG00000188191	1.4996998963482278	[246]	[303]	9	hSpCas9	negative selection	10894492
711373	711396	7	+	28162770	PL21	viability	GTTCGGGCTTGGAGATGCAGAGG	PRKAR1B	ENSG00000188191	-1.6033935966158754	[376]	[53]	-7	hSpCas9	negative selection	10894493
711337	711360	7	+	28162770	P31FUJ	viability	GCTTCTCGAAGTGCTCCCGGAGG	PRKAR1B	ENSG00000188191	0.227927385557334	[201]	[277]	2	hSpCas9	negative selection	11063850
680700	680723	7	-	28162770	P31FUJ	viability	AAAACAGGCAGATTTTGGCGCGG	PRKAR1B	ENSG00000188191	1.0302322014194154	[249]	[599]	9	hSpCas9	negative selection	11063851
596264	596287	7	-	28162770	P31FUJ	viability	TGGGTGACCAACATCAGCGAGGG	PRKAR1B	ENSG00000188191	1.162921819807631	[140]	[370]	9	hSpCas9	negative selection	11063852
680582	680605	7	-	28162770	P31FUJ	viability	GAGTGCCGAGGTGTACACCGAGG	PRKAR1B	ENSG00000188191	0.2220997557424046	[115]	[158]	2	hSpCas9	negative selection	11063853
579345	579368	7	-	28162770	P31FUJ	viability	GAAGTGGGAGCGTCTGACCGTGG	PRKAR1B	ENSG00000188191	0.6416669135017625	[71]	[131]	7	hSpCas9	negative selection	11063854
579328	579351	7	+	28162770	P31FUJ	viability	GGGCTCCAGCGCATCCGCCACGG	PRKAR1B	ENSG00000188191	-0.22514863187094333	[187]	[188]	-2	hSpCas9	negative selection	11063855
551381	551404	7	+	28162770	P31FUJ	viability	GGACTCACCGAAGTAGTCAGAGG	PRKAR1B	ENSG00000188191	0.301887089825554	[291]	[422]	3	hSpCas9	negative selection	11063856
711457	711480	7	-	28162770	P31FUJ	viability	GGAGGAGGACGAGAGCCTGAAGG	PRKAR1B	ENSG00000188191	0.9027853893847967	[136]	[300]	9	hSpCas9	negative selection	11063857
711418	711441	7	-	28162770	P31FUJ	viability	GCAGCTGCACGGGATCCAGCAGG	PRKAR1B	ENSG00000188191	0.8983153478277589	[246]	[540]	8	hSpCas9	negative selection	11063858
711373	711396	7	+	28162770	P31FUJ	viability	GTTCGGGCTTGGAGATGCAGAGG	PRKAR1B	ENSG00000188191	0.3762959363293148	[572]	[873]	4	hSpCas9	negative selection	11063859
711337	711360	7	+	28162770	OCIAML5	viability	GCTTCTCGAAGTGCTCCCGGAGG	PRKAR1B	ENSG00000188191	-0.15654569499514231	[112]	[182]	-1	hSpCas9	negative selection	11233216
680700	680723	7	-	28162770	OCIAML5	viability	AAAACAGGCAGATTTTGGCGCGG	PRKAR1B	ENSG00000188191	0.3351779067783416	[183]	[418]	3	hSpCas9	negative selection	11233217
596264	596287	7	-	28162770	OCIAML5	viability	TGGGTGACCAACATCAGCGAGGG	PRKAR1B	ENSG00000188191	-0.4009598168776314	[78]	[107]	-3	hSpCas9	negative selection	11233218
680582	680605	7	-	28162770	OCIAML5	viability	GAGTGCCGAGGTGTACACCGAGG	PRKAR1B	ENSG00000188191	0.118186085741951	[48]	[95]	1	hSpCas9	negative selection	11233219
579345	579368	7	-	28162770	OCIAML5	viability	GAAGTGGGAGCGTCTGACCGTGG	PRKAR1B	ENSG00000188191	-1.2264620856454949	[34]	[26]	-6	hSpCas9	negative selection	11233220
579328	579351	7	+	28162770	OCIAML5	viability	GGGCTCCAGCGCATCCGCCACGG	PRKAR1B	ENSG00000188191	0.4295976538096382	[108]	[264]	3	hSpCas9	negative selection	11233221
551381	551404	7	+	28162770	OCIAML5	viability	GGACTCACCGAAGTAGTCAGAGG	PRKAR1B	ENSG00000188191	0.1260186527075624	[198]	[391]	1	hSpCas9	negative selection	11233222
711457	711480	7	-	28162770	OCIAML5	viability	GGAGGAGGACGAGAGCCTGAAGG	PRKAR1B	ENSG00000188191	1.4272696472988975	[54]	[266]	9	hSpCas9	negative selection	11233223
711418	711441	7	-	28162770	OCIAML5	viability	GCAGCTGCACGGGATCCAGCAGG	PRKAR1B	ENSG00000188191	0.7147485831468999	[79]	[236]	6	hSpCas9	negative selection	11233224
711373	711396	7	+	28162770	OCIAML5	viability	GTTCGGGCTTGGAGATGCAGAGG	PRKAR1B	ENSG00000188191	0.010720742004508788	[247]	[450]	0	hSpCas9	negative selection	11233225
711337	711360	7	+	28162770	EOL1	viability	GCTTCTCGAAGTGCTCCCGGAGG	PRKAR1B	ENSG00000188191	0.4517141070954573	[364]	[262]	4	hSpCas9	negative selection	11402582
680700	680723	7	-	28162770	EOL1	viability	AAAACAGGCAGATTTTGGCGCGG	PRKAR1B	ENSG00000188191	0.3615000472778189	[293]	[198]	3	hSpCas9	negative selection	11402583
596264	596287	7	-	28162770	EOL1	viability	TGGGTGACCAACATCAGCGAGGG	PRKAR1B	ENSG00000188191	-0.590809261664755	[262]	[91]	-4	hSpCas9	negative selection	11402584
680582	680605	7	-	28162770	EOL1	viability	GAGTGCCGAGGTGTACACCGAGG	PRKAR1B	ENSG00000188191	-0.42385253467801887	[274]	[107]	-3	hSpCas9	negative selection	11402585
579345	579368	7	-	28162770	EOL1	viability	GAAGTGGGAGCGTCTGACCGTGG	PRKAR1B	ENSG00000188191	0.8814790496786485	[101]	[98]	7	hSpCas9	negative selection	11402586
579328	579351	7	+	28162770	EOL1	viability	GGGCTCCAGCGCATCCGCCACGG	PRKAR1B	ENSG00000188191	0.42148552449446663	[427]	[301]	4	hSpCas9	negative selection	11402587
551381	551404	7	+	28162770	EOL1	viability	GGACTCACCGAAGTAGTCAGAGG	PRKAR1B	ENSG00000188191	0.641769430438326	[308]	[253]	6	hSpCas9	negative selection	11402588
711457	711480	7	-	28162770	EOL1	viability	GGAGGAGGACGAGAGCCTGAAGG	PRKAR1B	ENSG00000188191	0.0020843720415547606	[162]	[85]	0	hSpCas9	negative selection	11402589
711418	711441	7	-	28162770	EOL1	viability	GCAGCTGCACGGGATCCAGCAGG	PRKAR1B	ENSG00000188191	-0.26233036315297503	[320]	[140]	-2	hSpCas9	negative selection	11402590
711373	711396	7	+	28162770	EOL1	viability	GTTCGGGCTTGGAGATGCAGAGG	PRKAR1B	ENSG00000188191	1.1246873860598545	[503]	[578]	8	hSpCas9	negative selection	11402591
711337	711360	7	+	28162770	MOLM13	viability	GCTTCTCGAAGTGCTCCCGGAGG	PRKAR1B	ENSG00000188191	1.1555655687143136	[261]	[421]	8	hSpCas9	negative selection	11571948
680700	680723	7	-	28162770	MOLM13	viability	AAAACAGGCAGATTTTGGCGCGG	PRKAR1B	ENSG00000188191	0.6897011246518598	[354]	[413]	5	hSpCas9	negative selection	11571949
596264	596287	7	-	28162770	MOLM13	viability	TGGGTGACCAACATCAGCGAGGG	PRKAR1B	ENSG00000188191	-0.799806401659078	[247]	[102]	-4	hSpCas9	negative selection	11571950
680582	680605	7	-	28162770	MOLM13	viability	GAGTGCCGAGGTGTACACCGAGG	PRKAR1B	ENSG00000188191	0.8750647630504522	[183]	[243]	6	hSpCas9	negative selection	11571951
579345	579368	7	-	28162770	MOLM13	viability	GAAGTGGGAGCGTCTGACCGTGG	PRKAR1B	ENSG00000188191	0.7461905440316831	[93]	[113]	5	hSpCas9	negative selection	11571952
579328	579351	7	+	28162770	MOLM13	viability	GGGCTCCAGCGCATCCGCCACGG	PRKAR1B	ENSG00000188191	1.0777430578074458	[248]	[379]	7	hSpCas9	negative selection	11571953
551381	551404	7	+	28162770	MOLM13	viability	GGACTCACCGAAGTAGTCAGAGG	PRKAR1B	ENSG00000188191	0.2923583244660305	[418]	[370]	2	hSpCas9	negative selection	11571954
711457	711480	7	-	28162770	MOLM13	viability	GGAGGAGGACGAGAGCCTGAAGG	PRKAR1B	ENSG00000188191	-0.3713144065523652	[228]	[127]	-2	hSpCas9	negative selection	11571955
711418	711441	7	-	28162770	MOLM13	viability	GCAGCTGCACGGGATCCAGCAGG	PRKAR1B	ENSG00000188191	-0.9562013659871518	[372]	[138]	-5	hSpCas9	negative selection	11571956
711373	711396	7	+	28162770	MOLM13	viability	GTTCGGGCTTGGAGATGCAGAGG	PRKAR1B	ENSG00000188191	0.4837143487062615	[543]	[549]	3	hSpCas9	negative selection	11571957
711337	711360	7	+	28162770	HEL	viability	GCTTCTCGAAGTGCTCCCGGAGG	PRKAR1B	ENSG00000188191	0.18474918753696618	[249]	[181]	1	hSpCas9	negative selection	11741314
680700	680723	7	-	28162770	HEL	viability	AAAACAGGCAGATTTTGGCGCGG	PRKAR1B	ENSG00000188191	1.0285225263040867	[273]	[357]	8	hSpCas9	negative selection	11741315
596264	596287	7	-	28162770	HEL	viability	TGGGTGACCAACATCAGCGAGGG	PRKAR1B	ENSG00000188191	0.7829164900486173	[195]	[215]	6	hSpCas9	negative selection	11741316
680582	680605	7	-	28162770	HEL	viability	GAGTGCCGAGGTGTACACCGAGG	PRKAR1B	ENSG00000188191	0.7150896762250408	[174]	[183]	6	hSpCas9	negative selection	11741317
579345	579368	7	-	28162770	HEL	viability	GAAGTGGGAGCGTCTGACCGTGG	PRKAR1B	ENSG00000188191	0.18115874678448285	[83]	[60]	1	hSpCas9	negative selection	11741318
579328	579351	7	+	28162770	HEL	viability	GGGCTCCAGCGCATCCGCCACGG	PRKAR1B	ENSG00000188191	0.817681908209294	[286]	[323]	7	hSpCas9	negative selection	11741319
551381	551404	7	+	28162770	HEL	viability	GGACTCACCGAAGTAGTCAGAGG	PRKAR1B	ENSG00000188191	0.5663879458702421	[290]	[275]	5	hSpCas9	negative selection	11741320
711457	711480	7	-	28162770	HEL	viability	GGAGGAGGACGAGAGCCTGAAGG	PRKAR1B	ENSG00000188191	-0.18276343676750662	[139]	[78]	-1	hSpCas9	negative selection	11741321
711418	711441	7	-	28162770	HEL	viability	GCAGCTGCACGGGATCCAGCAGG	PRKAR1B	ENSG00000188191	0.6879051480484918	[282]	[291]	6	hSpCas9	negative selection	11741322
711373	711396	7	+	28162770	HEL	viability	GTTCGGGCTTGGAGATGCAGAGG	PRKAR1B	ENSG00000188191	0.44877481899042637	[468]	[409]	4	hSpCas9	negative selection	11741323
711337	711360	7	+	28162770	MV411	viability	GCTTCTCGAAGTGCTCCCGGAGG	PRKAR1B	ENSG00000188191	-0.05974395873540084	[218]	[176]	0	hSpCas9	negative selection	11910680
680700	680723	7	-	28162770	MV411	viability	AAAACAGGCAGATTTTGGCGCGG	PRKAR1B	ENSG00000188191	1.2474375507827755	[172]	[345]	9	hSpCas9	negative selection	11910681
596264	596287	7	-	28162770	MV411	viability	TGGGTGACCAACATCAGCGAGGG	PRKAR1B	ENSG00000188191	-0.5301700278807767	[143]	[83]	-4	hSpCas9	negative selection	11910682
680582	680605	7	-	28162770	MV411	viability	GAGTGCCGAGGTGTACACCGAGG	PRKAR1B	ENSG00000188191	-1.2458944744728124	[182]	[64]	-7	hSpCas9	negative selection	11910683
579345	579368	7	-	28162770	MV411	viability	GAAGTGGGAGCGTCTGACCGTGG	PRKAR1B	ENSG00000188191	-0.8803179964155972	[58]	[26]	-6	hSpCas9	negative selection	11910684
579328	579351	7	+	28162770	MV411	viability	GGGCTCCAGCGCATCCGCCACGG	PRKAR1B	ENSG00000188191	0.19945752188095353	[213]	[206]	1	hSpCas9	negative selection	11910685
551381	551404	7	+	28162770	MV411	viability	GGACTCACCGAAGTAGTCAGAGG	PRKAR1B	ENSG00000188191	0.022224610383948684	[255]	[218]	0	hSpCas9	negative selection	11910686
711457	711480	7	-	28162770	MV411	viability	GGAGGAGGACGAGAGCCTGAAGG	PRKAR1B	ENSG00000188191	0.5647783761744858	[125]	[156]	5	hSpCas9	negative selection	11910687
711418	711441	7	-	28162770	MV411	viability	GCAGCTGCACGGGATCCAGCAGG	PRKAR1B	ENSG00000188191	0.343464438556551	[246]	[263]	3	hSpCas9	negative selection	11910688
711373	711396	7	+	28162770	MV411	viability	GTTCGGGCTTGGAGATGCAGAGG	PRKAR1B	ENSG00000188191	0.40078832768957173	[320]	[356]	3	hSpCas9	negative selection	11910689
711337	711360	7	+	28162770	MONOMAC1	viability	GCTTCTCGAAGTGCTCCCGGAGG	PRKAR1B	ENSG00000188191	-0.07065956128999834	[141]	[154]	0	hSpCas9	negative selection	12080046
680700	680723	7	-	28162770	MONOMAC1	viability	AAAACAGGCAGATTTTGGCGCGG	PRKAR1B	ENSG00000188191	0.484330137614665	[163]	[262]	5	hSpCas9	negative selection	12080047
596264	596287	7	-	28162770	MONOMAC1	viability	TGGGTGACCAACATCAGCGAGGG	PRKAR1B	ENSG00000188191	0.30450964547396486	[88]	[125]	3	hSpCas9	negative selection	12080048
680582	680605	7	-	28162770	MONOMAC1	viability	GAGTGCCGAGGTGTACACCGAGG	PRKAR1B	ENSG00000188191	0.8574109369628228	[64]	[134]	7	hSpCas9	negative selection	12080049
579345	579368	7	-	28162770	MONOMAC1	viability	GAAGTGGGAGCGTCTGACCGTGG	PRKAR1B	ENSG00000188191	0.3144634917205815	[46]	[66]	3	hSpCas9	negative selection	12080050
579328	579351	7	+	28162770	MONOMAC1	viability	GGGCTCCAGCGCATCCGCCACGG	PRKAR1B	ENSG00000188191	-0.06445120744174426	[186]	[204]	0	hSpCas9	negative selection	12080051
551381	551404	7	+	28162770	MONOMAC1	viability	GGACTCACCGAAGTAGTCAGAGG	PRKAR1B	ENSG00000188191	0.4257785526601408	[162]	[250]	4	hSpCas9	negative selection	12080052
711457	711480	7	-	28162770	MONOMAC1	viability	GGAGGAGGACGAGAGCCTGAAGG	PRKAR1B	ENSG00000188191	0.8527161881375458	[56]	[117]	7	hSpCas9	negative selection	12080053
711418	711441	7	-	28162770	MONOMAC1	viability	GCAGCTGCACGGGATCCAGCAGG	PRKAR1B	ENSG00000188191	1.7675410987296154	[133]	[522]	9	hSpCas9	negative selection	12080054
711373	711396	7	+	28162770	MONOMAC1	viability	GTTCGGGCTTGGAGATGCAGAGG	PRKAR1B	ENSG00000188191	0.02859758696904624	[253]	[296]	0	hSpCas9	negative selection	12080055
711337	711360	7	+	28162770	OCIAML2	viability	GCTTCTCGAAGTGCTCCCGGAGG	PRKAR1B	ENSG00000188191	0.13602774657831396	[43]	[267]	1	hSpCas9	negative selection	12249412
680700	680723	7	-	28162770	OCIAML2	viability	AAAACAGGCAGATTTTGGCGCGG	PRKAR1B	ENSG00000188191	0.8919402541425471	[41]	[431]	8	hSpCas9	negative selection	12249413
596264	596287	7	-	28162770	OCIAML2	viability	TGGGTGACCAACATCAGCGAGGG	PRKAR1B	ENSG00000188191	-0.4706298252421611	[32]	[131]	-4	hSpCas9	negative selection	12249414
680582	680605	7	-	28162770	OCIAML2	viability	GAGTGCCGAGGTGTACACCGAGG	PRKAR1B	ENSG00000188191	0.07051644318650546	[38]	[226]	0	hSpCas9	negative selection	12249415
579345	579368	7	-	28162770	OCIAML2	viability	GAAGTGGGAGCGTCTGACCGTGG	PRKAR1B	ENSG00000188191	0.6992951762001509	[12]	[116]	6	hSpCas9	negative selection	12249416
579328	579351	7	+	28162770	OCIAML2	viability	GGGCTCCAGCGCATCCGCCACGG	PRKAR1B	ENSG00000188191	0.114332675478995	[43]	[263]	1	hSpCas9	negative selection	12249417
551381	551404	7	+	28162770	OCIAML2	viability	GGACTCACCGAAGTAGTCAGAGG	PRKAR1B	ENSG00000188191	0.6675863164728131	[45]	[404]	6	hSpCas9	negative selection	12249418
711457	711480	7	-	28162770	OCIAML2	viability	GGAGGAGGACGAGAGCCTGAAGG	PRKAR1B	ENSG00000188191	-0.622632918687211	[24]	[89]	-5	hSpCas9	negative selection	12249419
711418	711441	7	-	28162770	OCIAML2	viability	GCAGCTGCACGGGATCCAGCAGG	PRKAR1B	ENSG00000188191	-0.3710941516912468	[48]	[209]	-3	hSpCas9	negative selection	12249420
711373	711396	7	+	28162770	OCIAML2	viability	GTTCGGGCTTGGAGATGCAGAGG	PRKAR1B	ENSG00000188191	0.12693271225862846	[56]	[344]	1	hSpCas9	negative selection	12249421
711337	711360	7	+	28162770	OCIAML3	viability	GCTTCTCGAAGTGCTCCCGGAGG	PRKAR1B	ENSG00000188191	-0.4292628779875309	[61]	[138]	-3	hSpCas9	negative selection	12418778
680700	680723	7	-	28162770	OCIAML3	viability	AAAACAGGCAGATTTTGGCGCGG	PRKAR1B	ENSG00000188191	1.531523241759696	[76]	[671]	9	hSpCas9	negative selection	12418779
596264	596287	7	-	28162770	OCIAML3	viability	TGGGTGACCAACATCAGCGAGGG	PRKAR1B	ENSG00000188191	0.14295795384204307	[62]	[209]	1	hSpCas9	negative selection	12418780
680582	680605	7	-	28162770	OCIAML3	viability	GAGTGCCGAGGTGTACACCGAGG	PRKAR1B	ENSG00000188191	0.7937225129589454	[29]	[156]	7	hSpCas9	negative selection	12418781
579345	579368	7	-	28162770	OCIAML3	viability	GAAGTGGGAGCGTCTGACCGTGG	PRKAR1B	ENSG00000188191	1.0327750360916201	[16]	[104]	8	hSpCas9	negative selection	12418782
579328	579351	7	+	28162770	OCIAML3	viability	GGGCTCCAGCGCATCCGCCACGG	PRKAR1B	ENSG00000188191	-1.594007640324163	[61]	[61]	-8	hSpCas9	negative selection	12418783
551381	551404	7	+	28162770	OCIAML3	viability	GGACTCACCGAAGTAGTCAGAGG	PRKAR1B	ENSG00000188191	0.8799235480082491	[53]	[299]	7	hSpCas9	negative selection	12418784
711457	711480	7	-	28162770	OCIAML3	viability	GGAGGAGGACGAGAGCCTGAAGG	PRKAR1B	ENSG00000188191	1.8597103271187403	[22]	[251]	9	hSpCas9	negative selection	12418785
711418	711441	7	-	28162770	OCIAML3	viability	GCAGCTGCACGGGATCCAGCAGG	PRKAR1B	ENSG00000188191	-0.8835142575191479	[76]	[125]	-6	hSpCas9	negative selection	12418786
711373	711396	7	+	28162770	OCIAML3	viability	GTTCGGGCTTGGAGATGCAGAGG	PRKAR1B	ENSG00000188191	0.8707672993874439	[97]	[540]	7	hSpCas9	negative selection	12418787