Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:5593
• Symbol:PRKG2
• Description:protein kinase cGMP-dependent 2

DataSource: http://genomecrispr.dkfz.de/#!/results/PRKG2

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
81204927	81204950	4	-	26472758	Jiyoye	viability	GGAGAGAGAGTTGAGGAGGAAGG	PRKG2	ENSG00000138669	-5.139719078381764	[186]	[3]	-9	hSpCas9	negative selection	127528
81204907	81204930	4	-	26472758	Jiyoye	viability	AGGATGCTGAGATCCAGGAGCGG	PRKG2	ENSG00000138669	1.4071753815058732	[88]	[177]	8	hSpCas9	negative selection	127529
81204776	81204799	4	-	26472758	Jiyoye	viability	GATGTGGTGCATATGCAGGGAGG	PRKG2	ENSG00000138669	-0.13246312870579252	[140]	[96]	-1	hSpCas9	negative selection	127530
81204711	81204734	4	+	26472758	Jiyoye	viability	CCAATCCAGAGGTCTTCCGGTGG	PRKG2	ENSG00000138669	0.6803859407519379	[258]	[312]	5	hSpCas9	negative selection	127531
81204700	81204723	4	+	26472758	Jiyoye	viability	ATGGAGAGAGACCAATCCAGAGG	PRKG2	ENSG00000138669	0.2734239926170461	[191]	[174]	2	hSpCas9	negative selection	127532
81142877	81142900	4	-	26472758	Jiyoye	viability	GATTCAGCTGAAGGAGAAGGTGG	PRKG2	ENSG00000138669	-0.23815973719476458	[60]	[38]	-2	hSpCas9	negative selection	127533
81105913	81105936	4	+	26472758	Jiyoye	viability	GGTCAACCCCAGAAAAGGGTGGG	PRKG2	ENSG00000138669	2.4071753815058727	[0]	[3]	9	hSpCas9	negative selection	127534
81105835	81105858	4	-	26472758	Jiyoye	viability	GAAGATAACACGACGACCTGAGG	PRKG2	ENSG00000138669	-0.29116891863302535	[171]	[105]	-2	hSpCas9	negative selection	127535
81204927	81204950	4	-	26472758	KBM7	viability	GGAGAGAGAGTTGAGGAGGAAGG	PRKG2	ENSG00000138669	-1.6155538907404545	[267,202]	[48,23]	-8	hSpCas9	negative selection	318646
81204907	81204930	4	-	26472758	KBM7	viability	AGGATGCTGAGATCCAGGAGCGG	PRKG2	ENSG00000138669	0.6648888300480083	[447,404]	[367,272]	7	hSpCas9	negative selection	318647
81204776	81204799	4	-	26472758	KBM7	viability	GATGTGGTGCATATGCAGGGAGG	PRKG2	ENSG00000138669	0.15170737679979945	[715,471]	[460,165]	1	hSpCas9	negative selection	318648
81204711	81204734	4	+	26472758	KBM7	viability	CCAATCCAGAGGTCTTCCGGTGG	PRKG2	ENSG00000138669	1.4731744097944492	[809,563]	[832,930]	9	hSpCas9	negative selection	318649
81204700	81204723	4	+	26472758	KBM7	viability	ATGGAGAGAGACCAATCCAGAGG	PRKG2	ENSG00000138669	-0.4040139126428944	[932,490]	[298,198]	-4	hSpCas9	negative selection	318650
81142877	81142900	4	-	26472758	KBM7	viability	GATTCAGCTGAAGGAGAAGGTGG	PRKG2	ENSG00000138669	0.17861125676792022	[299,283]	[113,192]	1	hSpCas9	negative selection	318651
81105913	81105936	4	+	26472758	KBM7	viability	GGTCAACCCCAGAAAAGGGTGGG	PRKG2	ENSG00000138669	-0.1996158756776545	[89,33]	[17,29]	-2	hSpCas9	negative selection	318652
81105835	81105858	4	-	26472758	KBM7	viability	GAAGATAACACGACGACCTGAGG	PRKG2	ENSG00000138669	0.3987732860004749	[993,835]	[480,639]	4	hSpCas9	negative selection	318653
81204927	81204950	4	-	26472758	Raji	viability	GGAGAGAGAGTTGAGGAGGAAGG	PRKG2	ENSG00000138669	-5.416178420683414	[183]	[0]	-9	hSpCas9	negative selection	509764
81204907	81204930	4	-	26472758	Raji	viability	AGGATGCTGAGATCCAGGAGCGG	PRKG2	ENSG00000138669	-0.006572653923485994	[315]	[72]	0	hSpCas9	negative selection	509765
81204776	81204799	4	-	26472758	Raji	viability	GATGTGGTGCATATGCAGGGAGG	PRKG2	ENSG00000138669	-1.366547652958813	[299]	[26]	-7	hSpCas9	negative selection	509766
81204711	81204734	4	+	26472758	Raji	viability	CCAATCCAGAGGTCTTCCGGTGG	PRKG2	ENSG00000138669	0.039338147950500724	[368]	[87]	0	hSpCas9	negative selection	509767
81204700	81204723	4	+	26472758	Raji	viability	ATGGAGAGAGACCAATCCAGAGG	PRKG2	ENSG00000138669	-0.44343074293571116	[333]	[56]	-4	hSpCas9	negative selection	509768
81142877	81142900	4	-	26472758	Raji	viability	GATTCAGCTGAAGGAGAAGGTGG	PRKG2	ENSG00000138669	-0.5521259187126106	[138]	[21]	-4	hSpCas9	negative selection	509769
81105913	81105936	4	+	26472758	Raji	viability	GGTCAACCCCAGAAAAGGGTGGG	PRKG2	ENSG00000138669	-3.477578965347557	[47]	[0]	-9	hSpCas9	negative selection	509770
81105835	81105858	4	-	26472758	Raji	viability	GAAGATAACACGACGACCTGAGG	PRKG2	ENSG00000138669	-0.3416564774171021	[414]	[75]	-3	hSpCas9	negative selection	509771
81204927	81204950	4	-	26472758	K562	viability	GGAGAGAGAGTTGAGGAGGAAGG	PRKG2	ENSG00000138669	-7.92048819900924	[286]	[0]	-9	hSpCas9	negative selection	700882
81204907	81204930	4	-	26472758	K562	viability	AGGATGCTGAGATCCAGGAGCGG	PRKG2	ENSG00000138669	1.3133138088775143	[367]	[771]	9	hSpCas9	negative selection	700883
81204776	81204799	4	-	26472758	K562	viability	GATGTGGTGCATATGCAGGGAGG	PRKG2	ENSG00000138669	0.6730391992182158	[369]	[497]	5	hSpCas9	negative selection	700884
81204711	81204734	4	+	26472758	K562	viability	CCAATCCAGAGGTCTTCCGGTGG	PRKG2	ENSG00000138669	1.0527852391362265	[610]	[1069]	8	hSpCas9	negative selection	700885
81204700	81204723	4	+	26472758	K562	viability	ATGGAGAGAGACCAATCCAGAGG	PRKG2	ENSG00000138669	-1.4466561863206648	[690]	[213]	-6	hSpCas9	negative selection	700886
81142877	81142900	4	-	26472758	K562	viability	GATTCAGCTGAAGGAGAAGGTGG	PRKG2	ENSG00000138669	-0.2613170819041344	[185]	[130]	-2	hSpCas9	negative selection	700887
81105913	81105936	4	+	26472758	K562	viability	GGTCAACCCCAGAAAAGGGTGGG	PRKG2	ENSG00000138669	0.7969597506952253	[44]	[65]	6	hSpCas9	negative selection	700888
81105835	81105858	4	-	26472758	K562	viability	GAAGATAACACGACGACCTGAGG	PRKG2	ENSG00000138669	0.37357088198345945	[629]	[688]	3	hSpCas9	negative selection	700889
81148879	81148902	4	+	26627737	DLD1	viability	CTCACTCTCGATCTATAACCAGG	PRKG2	ENSG00000138669	0.39058868171874594	[902]	[327,308,456]	4	hSpCas9	negative selection	825952
81153679	81153702	4	-	26627737	DLD1	viability	TTACATCATTAGAGAGGGCGAGG	PRKG2	ENSG00000138669	-0.025408780642474038	[641]	[132,237,218]	0	hSpCas9	negative selection	825955
81204691	81204714	4	-	26627737	DLD1	viability	TGGTCTCTCTCCATAGCAGGAGG	PRKG2	ENSG00000138669	0.06664593150751003	[332]	[150,145,41]	0	hSpCas9	negative selection	825957
81148879	81148902	4	+	26627737	GBM cells	viability after 5 days	CTCACTCTCGATCTATAACCAGG	PRKG2	ENSG00000138669	-0.39644250213695353	[658]	[217,318]	-6	hSpCas9	negative selection	908267
81153679	81153702	4	-	26627737	GBM cells	viability after 5 days	TTACATCATTAGAGAGGGCGAGG	PRKG2	ENSG00000138669	0.3164980562748759	[282]	[191,185]	5	hSpCas9	negative selection	908270
81204691	81204714	4	-	26627737	GBM cells	viability after 5 days	TGGTCTCTCTCCATAGCAGGAGG	PRKG2	ENSG00000138669	0.25799496819051404	[183]	[102,132]	4	hSpCas9	negative selection	908272
81148879	81148902	4	+	26627737	GBM cells	viability after 13 days	CTCACTCTCGATCTATAACCAGG	PRKG2	ENSG00000138669	-0.4885935894498784	[658]	[277,235]	-5	hSpCas9	negative selection	990582
81153679	81153702	4	-	26627737	GBM cells	viability after 13 days	TTACATCATTAGAGAGGGCGAGG	PRKG2	ENSG00000138669	0.9469699206205499	[282]	[402,208]	9	hSpCas9	negative selection	990585
81204691	81204714	4	-	26627737	GBM cells	viability after 13 days	TGGTCTCTCTCCATAGCAGGAGG	PRKG2	ENSG00000138669	-0.2529349828582512	[183]	[128,46]	-3	hSpCas9	negative selection	990587
81148879	81148902	4	+	26627737	GBM cells	viability after 21 days	CTCACTCTCGATCTATAACCAGG	PRKG2	ENSG00000138669	-0.752431462185775	[658]	[211,212]	-6	hSpCas9	negative selection	1072897
81153679	81153702	4	-	26627737	GBM cells	viability after 21 days	TTACATCATTAGAGAGGGCGAGG	PRKG2	ENSG00000138669	0.8214458121183886	[282]	[313,232]	7	hSpCas9	negative selection	1072900
81204691	81204714	4	-	26627737	GBM cells	viability after 21 days	TGGTCTCTCTCCATAGCAGGAGG	PRKG2	ENSG00000138669	-0.6543915516752126	[183]	[74,52]	-5	hSpCas9	negative selection	1072902
81148879	81148902	4	+	26627737	RPE1	viability after 9 days	CTCACTCTCGATCTATAACCAGG	PRKG2	ENSG00000138669	0.6156488004886544	[1022]	[636,301]	4	hSpCas9	negative selection	1155212
81153679	81153702	4	-	26627737	RPE1	viability after 9 days	TTACATCATTAGAGAGGGCGAGG	PRKG2	ENSG00000138669	-0.10233181180290457	[985]	[156,455]	0	hSpCas9	negative selection	1155215
81204691	81204714	4	-	26627737	RPE1	viability after 9 days	TGGTCTCTCTCCATAGCAGGAGG	PRKG2	ENSG00000138669	-0.10086962575773634	[691]	[208,192]	0	hSpCas9	negative selection	1155217
81148879	81148902	4	+	26627737	RPE1	viability after 12 days	CTCACTCTCGATCTATAACCAGG	PRKG2	ENSG00000138669	0.6884977643111441	[1022]	[627,246]	4	hSpCas9	negative selection	1237527
81153679	81153702	4	-	26627737	RPE1	viability after 12 days	TTACATCATTAGAGAGGGCGAGG	PRKG2	ENSG00000138669	0.0734586011464437	[985]	[99,467]	0	hSpCas9	negative selection	1237530
81204691	81204714	4	-	26627737	RPE1	viability after 12 days	TGGTCTCTCTCCATAGCAGGAGG	PRKG2	ENSG00000138669	0.05692716862589198	[691]	[240,142]	0	hSpCas9	negative selection	1237532
81148879	81148902	4	+	26627737	RPE1	viability after 15 days	CTCACTCTCGATCTATAACCAGG	PRKG2	ENSG00000138669	0.40843541210757245	[1022]	[519,252]	2	hSpCas9	negative selection	1319842
81153679	81153702	4	-	26627737	RPE1	viability after 15 days	TTACATCATTAGAGAGGGCGAGG	PRKG2	ENSG00000138669	-0.0032752736308894193	[985]	[205,347]	0	hSpCas9	negative selection	1319845
81204691	81204714	4	-	26627737	RPE1	viability after 15 days	TGGTCTCTCTCCATAGCAGGAGG	PRKG2	ENSG00000138669	-0.005281248178744202	[691]	[192,196]	0	hSpCas9	negative selection	1319847
81148879	81148902	4	+	26627737	RPE1	viability after 18 days	CTCACTCTCGATCTATAACCAGG	PRKG2	ENSG00000138669	-0.020755648257227366	[1022]	[377,158]	0	hSpCas9	negative selection	1402157
81153679	81153702	4	-	26627737	RPE1	viability after 18 days	TTACATCATTAGAGAGGGCGAGG	PRKG2	ENSG00000138669	0.0017670904785314079	[985]	[161,377]	0	hSpCas9	negative selection	1402160
81204691	81204714	4	-	26627737	RPE1	viability after 18 days	TGGTCTCTCTCCATAGCAGGAGG	PRKG2	ENSG00000138669	-0.15247975829263294	[691]	[153,182]	-1	hSpCas9	negative selection	1402162
81148879	81148902	4	+	26627737	HeLa	viability after 8 days	CTCACTCTCGATCTATAACCAGG	PRKG2	ENSG00000138669	-0.7115828740753888	[1067]	[361,332,180]	-6	hSpCas9	negative selection	1484472
81153679	81153702	4	-	26627737	HeLa	viability after 8 days	TTACATCATTAGAGAGGGCGAGG	PRKG2	ENSG00000138669	-0.1687574383768838	[392]	[175,123,160]	-2	hSpCas9	negative selection	1484475
81204691	81204714	4	-	26627737	HeLa	viability after 8 days	TGGTCTCTCTCCATAGCAGGAGG	PRKG2	ENSG00000138669	0.4094729358161101	[311]	[245,122,185]	4	hSpCas9	negative selection	1484477
81148879	81148902	4	+	26627737	HeLa	viability after 12 days	CTCACTCTCGATCTATAACCAGG	PRKG2	ENSG00000138669	-1.2020786079551704	[1067]	[79,250,234]	-8	hSpCas9	negative selection	1566787
81153679	81153702	4	-	26627737	HeLa	viability after 12 days	TTACATCATTAGAGAGGGCGAGG	PRKG2	ENSG00000138669	0.4477617182147815	[392]	[345,175,150]	4	hSpCas9	negative selection	1566790
81204691	81204714	4	-	26627737	HeLa	viability after 12 days	TGGTCTCTCTCCATAGCAGGAGG	PRKG2	ENSG00000138669	0.5022526553814877	[311]	[228,99,228]	4	hSpCas9	negative selection	1566792
81148879	81148902	4	+	26627737	HeLa	viability after 15 days	CTCACTCTCGATCTATAACCAGG	PRKG2	ENSG00000138669	-1.0820320391693863	[1067]	[81,326,208]	-7	hSpCas9	negative selection	1649102
81153679	81153702	4	-	26627737	HeLa	viability after 15 days	TTACATCATTAGAGAGGGCGAGG	PRKG2	ENSG00000138669	-0.30732764177590477	[392]	[166,107,110]	-3	hSpCas9	negative selection	1649105
81204691	81204714	4	-	26627737	HeLa	viability after 15 days	TGGTCTCTCTCCATAGCAGGAGG	PRKG2	ENSG00000138669	0.4759279335843013	[311]	[120,35,389]	4	hSpCas9	negative selection	1649107
81148879	81148902	4	+	26627737	HeLa	viability after 18 days	CTCACTCTCGATCTATAACCAGG	PRKG2	ENSG00000138669	-1.026874326786245	[1067]	[59,283,208]	-7	hSpCas9	negative selection	1731417
81153679	81153702	4	-	26627737	HeLa	viability after 18 days	TTACATCATTAGAGAGGGCGAGG	PRKG2	ENSG00000138669	-0.3038499310895339	[392]	[112,88,110]	-3	hSpCas9	negative selection	1731420
81204691	81204714	4	-	26627737	HeLa	viability after 18 days	TGGTCTCTCTCCATAGCAGGAGG	PRKG2	ENSG00000138669	0.4841576768212646	[311]	[82,29,389]	4	hSpCas9	negative selection	1731422
81148879	81148902	4	+	26627737	HCT116	viability after 6 days	CTCACTCTCGATCTATAACCAGG	PRKG2	ENSG00000138669	-0.48990588588197737	[912]	[214,39]	-3	hSpCas9	negative selection	1813732
81153679	81153702	4	-	26627737	HCT116	viability after 6 days	TTACATCATTAGAGAGGGCGAGG	PRKG2	ENSG00000138669	-0.8611259484701042	[466]	[71,22]	-5	hSpCas9	negative selection	1813735
81204691	81204714	4	-	26627737	HCT116	viability after 6 days	TGGTCTCTCTCCATAGCAGGAGG	PRKG2	ENSG00000138669	0.02288996107645913	[491]	[46,95]	0	hSpCas9	negative selection	1813737
81148879	81148902	4	+	26627737	HCT116	viability after 8 days	CTCACTCTCGATCTATAACCAGG	PRKG2	ENSG00000138669	-0.32322235691130874	[629]	[237,340,252]	-4	hSpCas9	negative selection	1896047
81153679	81153702	4	-	26627737	HCT116	viability after 8 days	TTACATCATTAGAGAGGGCGAGG	PRKG2	ENSG00000138669	0.5570402183366463	[295]	[255,208,254]	5	hSpCas9	negative selection	1896050
81204691	81204714	4	-	26627737	HCT116	viability after 8 days	TGGTCTCTCTCCATAGCAGGAGG	PRKG2	ENSG00000138669	0.4621822768687065	[188]	[198,137,94]	5	hSpCas9	negative selection	1896052
81148879	81148902	4	+	26627737	HCT116	viability after 9 days	CTCACTCTCGATCTATAACCAGG	PRKG2	ENSG00000138669	-0.24930389408417603	[912]	[227,186]	-2	hSpCas9	negative selection	1978362
81153679	81153702	4	-	26627737	HCT116	viability after 9 days	TTACATCATTAGAGAGGGCGAGG	PRKG2	ENSG00000138669	0.853685686166997	[466]	[326,144]	6	hSpCas9	negative selection	1978365
81204691	81204714	4	-	26627737	HCT116	viability after 9 days	TGGTCTCTCTCCATAGCAGGAGG	PRKG2	ENSG00000138669	-0.3377099791213125	[491]	[132,80]	-2	hSpCas9	negative selection	1978367
81148879	81148902	4	+	26627737	HCT116	viability after 12 days	CTCACTCTCGATCTATAACCAGG	PRKG2	ENSG00000138669	-0.2653126712961478	[629]	[194,214,421]	-3	hSpCas9	negative selection	2060677
81153679	81153702	4	-	26627737	HCT116	viability after 12 days	TTACATCATTAGAGAGGGCGAGG	PRKG2	ENSG00000138669	0.42739642092425856	[295]	[117,349,170]	4	hSpCas9	negative selection	2060680
81204691	81204714	4	-	26627737	HCT116	viability after 12 days	TGGTCTCTCTCCATAGCAGGAGG	PRKG2	ENSG00000138669	0.4313190538081575	[188]	[136,152,111]	4	hSpCas9	negative selection	2060682
81148879	81148902	4	+	26627737	HCT116	viability after 15 days	CTCACTCTCGATCTATAACCAGG	PRKG2	ENSG00000138669	-0.32989269100870955	[629]	[414,256,207]	-3	hSpCas9	negative selection	2142992
81153679	81153702	4	-	26627737	HCT116	viability after 15 days	TTACATCATTAGAGAGGGCGAGG	PRKG2	ENSG00000138669	0.4768580690520302	[295]	[334,173,212]	4	hSpCas9	negative selection	2142995
81204691	81204714	4	-	26627737	HCT116	viability after 15 days	TGGTCTCTCTCCATAGCAGGAGG	PRKG2	ENSG00000138669	0.34849832978686174	[188]	[240,121,64]	3	hSpCas9	negative selection	2142997
81148879	81148902	4	+	26627737	HCT116	viability after 18 days	CTCACTCTCGATCTATAACCAGG	PRKG2	ENSG00000138669	-0.2649039286656498	[629]	[185,207,374]	-2	hSpCas9	negative selection	2225307
81153679	81153702	4	-	26627737	HCT116	viability after 18 days	TTACATCATTAGAGAGGGCGAGG	PRKG2	ENSG00000138669	0.5679568174224517	[295]	[251,224,155]	5	hSpCas9	negative selection	2225310
81204691	81204714	4	-	26627737	HCT116	viability after 18 days	TGGTCTCTCTCCATAGCAGGAGG	PRKG2	ENSG00000138669	-0.0873259177914727	[188]	[86,119,46]	0	hSpCas9	negative selection	2225312
81204891	81204914	4	-	24336569	HL60	viability	GGAGCGGGAGTACCATTTGAAGG	PRKG2	ENSG00000138669	0.7591455640158653	[532]	[1908]	6	hSpCas9	negative selection	2286532
81204907	81204930	4	-	24336569	HL60	viability	AGGATGCTGAGATCCAGGAGCGG	PRKG2	ENSG00000138669	-0.7062652114160022	[871]	[1130]	-6	hSpCas9	negative selection	2286533
81204927	81204950	4	-	24336569	HL60	viability	GGAGAGAGAGTTGAGGAGGAAGG	PRKG2	ENSG00000138669	-1.9320598730807548	[888]	[492]	-9	hSpCas9	negative selection	2286534
81204934	81204957	4	-	24336569	HL60	viability	CAGAGCTGGAGAGAGAGTTGAGG	PRKG2	ENSG00000138669	0.21151262056233688	[603]	[1479]	2	hSpCas9	negative selection	2286535
81204948	81204971	4	-	24336569	HL60	viability	GCGGAACAAGGTGACAGAGCTGG	PRKG2	ENSG00000138669	-0.7089414524064999	[946]	[1225]	-6	hSpCas9	negative selection	2286536
81204960	81204983	4	-	24336569	HL60	viability	CACTGATGCTCTGCGGAACAAGG	PRKG2	ENSG00000138669	0.7905282869950322	[688]	[2521]	6	hSpCas9	negative selection	2286537
81204966	81204989	4	+	24336569	HL60	viability	TCCGCAGAGCATCAGTGGTGAGG	PRKG2	ENSG00000138669	-0.23269134299803418	[1858]	[3347]	-2	hSpCas9	negative selection	2286538
81204986	81205009	4	+	24336569	HL60	viability	AGGTTCCCAGAGTGTCCATCTGG	PRKG2	ENSG00000138669	0.9059980127057088	[1068]	[4238]	7	hSpCas9	negative selection	2286539
81204991	81205014	4	-	24336569	HL60	viability	AGCACCCAGATGGACACTCTGGG	PRKG2	ENSG00000138669	0.5368569970386907	[626]	[1924]	5	hSpCas9	negative selection	2286540
81205001	81205024	4	-	24336569	HL60	viability	AAACATTCTAAGCACCCAGATGG	PRKG2	ENSG00000138669	0.6209587037912978	[726]	[2365]	5	hSpCas9	negative selection	2286541
81204891	81204914	4	-	24336569	KBM7	viability	GGAGCGGGAGTACCATTTGAAGG	PRKG2	ENSG00000138669	0.32566582952860235	[482]	[1650]	3	hSpCas9	negative selection	2353709
81204907	81204930	4	-	24336569	KBM7	viability	AGGATGCTGAGATCCAGGAGCGG	PRKG2	ENSG00000138669	-0.8318933957704294	[572]	[877]	-6	hSpCas9	negative selection	2353710
81204927	81204950	4	-	24336569	KBM7	viability	GGAGAGAGAGTTGAGGAGGAAGG	PRKG2	ENSG00000138669	-2.378562022619361	[550]	[288]	-8	hSpCas9	negative selection	2353711
81204934	81204957	4	-	24336569	KBM7	viability	CAGAGCTGGAGAGAGAGTTGAGG	PRKG2	ENSG00000138669	-0.5340273653572863	[532]	[1003]	-4	hSpCas9	negative selection	2353712
81204948	81204971	4	-	24336569	KBM7	viability	GCGGAACAAGGTGACAGAGCTGG	PRKG2	ENSG00000138669	-0.32570420793079596	[674]	[1468]	-3	hSpCas9	negative selection	2353713
81204960	81204983	4	-	24336569	KBM7	viability	CACTGATGCTCTGCGGAACAAGG	PRKG2	ENSG00000138669	0.7201330820043177	[869]	[3908]	6	hSpCas9	negative selection	2353714
81204966	81204989	4	+	24336569	KBM7	viability	TCCGCAGAGCATCAGTGGTGAGG	PRKG2	ENSG00000138669	-0.4636152457675531	[1356]	[2683]	-4	hSpCas9	negative selection	2353715
81204986	81205009	4	+	24336569	KBM7	viability	AGGTTCCCAGAGTGTCCATCTGG	PRKG2	ENSG00000138669	0.7610941230805888	[799]	[3697]	6	hSpCas9	negative selection	2353716
81204991	81205014	4	-	24336569	KBM7	viability	AGCACCCAGATGGACACTCTGGG	PRKG2	ENSG00000138669	0.6271684437055232	[361]	[1524]	6	hSpCas9	negative selection	2353717
81205001	81205024	4	-	24336569	KBM7	viability	AAACATTCTAAGCACCCAGATGG	PRKG2	ENSG00000138669	0.040739383525569606	[889]	[2496]	0	hSpCas9	negative selection	2353718
81154979	81155002	4	-	25494202	A375	resistance to PLX-4720 (puromycin)	GGGGTTTCACCGTGTTAGCCGGG	PRKG2	ENSG00000138669	0.853016361217498	[78,47]	[31,16]	3	dCas9-VP64	positive selection	2418336
81154259	81154282	4	+	25494202	A375	resistance to PLX-4720 (puromycin)	GAGCCCGCCACAGCTCAAGGAGG	PRKG2	ENSG00000138669	0.383571547531365	[6,30]	[6,2]	1	dCas9-VP64	positive selection	2421793
81159867	81159890	4	-	25494202	A375	resistance to PLX-4720 (puromycin)	GAGTGAGAATATGCGGTGTTTAG	PRKG2	ENSG00000138669	-0.6843799399670565	[176,164]	[29,15]	-3	dCas9-VP64	positive selection	2432563
81154979	81155002	4	-	25494202	A375	resistance to PLX-4720 (zeocin)	GGGGTTTCACCGTGTTAGCCGGG	PRKG2	ENSG00000138669	1.9224239682243596	[76,41]	[141,10]	8	dCas9-VP64	positive selection	2513591
81154259	81154282	4	+	25494202	A375	resistance to PLX-4720 (zeocin)	GAGCCCGCCACAGCTCAAGGAGG	PRKG2	ENSG00000138669	-0.39903518405611826	[112,172]	[23,44]	-4	dCas9-VP64	positive selection	2517048
81159867	81159890	4	-	25494202	A375	resistance to PLX-4720 (zeocin)	GAGTGAGAATATGCGGTGTTTAG	PRKG2	ENSG00000138669	1.7345023813454719	[65,109]	[27,158]	8	dCas9-VP64	positive selection	2527818
81204858	81204881	4	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCAGCTGTCGAAGCAGACTGTGG	PRKG2	ENSG00000138669	-0.3723592219316614	[3,2]	[2,0]	-5	hSpCas9	positive selection	3013709
81204837	81204860	4	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GGCCATTGCTGAACTCACAGAGG	PRKG2	ENSG00000138669	0.14364976017064246	[4,4]	[4,4]	3	hSpCas9	positive selection	3013710
81153679	81153702	4	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TTACATCATTAGAGAGGGCGAGG	PRKG2	ENSG00000138669	0.81308894198249	[2,3]	[2,6]	9	hSpCas9	positive selection	3013711
81204858	81204881	4	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCAGCTGTCGAAGCAGACTGTGG	PRKG2	ENSG00000138669	0.004258651349673195	[3,3]	[2,1]	0	hSpCas9	positive selection	3081567
81204837	81204860	4	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GGCCATTGCTGAACTCACAGAGG	PRKG2	ENSG00000138669	0.2824283236275317	[4,4]	[5,3]	5	hSpCas9	positive selection	3081568
81153679	81153702	4	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TTACATCATTAGAGAGGGCGAGG	PRKG2	ENSG00000138669	-0.08484164489973234	[2,2]	[2,0]	-1	hSpCas9	positive selection	3081569
81204858	81204881	4	-	26780180	HT29	viability (Avana library 4 designs)	GCAGCTGTCGAAGCAGACTGTGG	PRKG2	ENSG00000138669	1.94655198388961	[]	[]	7	hSpCas9	negative selection	3451900
81204837	81204860	4	-	26780180	HT29	viability (Avana library 4 designs)	GGCCATTGCTGAACTCACAGAGG	PRKG2	ENSG00000138669	-0.68096271540558	[]	[]	-8	hSpCas9	negative selection	3451901
81153679	81153702	4	-	26780180	HT29	viability (Avana library 4 designs)	TTACATCATTAGAGAGGGCGAGG	PRKG2	ENSG00000138669	1.25924604917106	[]	[]	5	hSpCas9	negative selection	3451902
81204837	81204860	4	-	26780180	A375	viability (Avana lentiCRISPRv2)	GGCCATTGCTGAACTCACAGAGG	PRKG2	ENSG00000138669	-3.42101663259441	[]	[]	-4	hSpCas9	negative selection	3548014
81204858	81204881	4	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCAGCTGTCGAAGCAGACTGTGG	PRKG2	ENSG00000138669	2.86917551632813	[]	[]	4	hSpCas9	negative selection	3548015
81153679	81153702	4	-	26780180	A375	viability (Avana lentiCRISPRv2)	TTACATCATTAGAGAGGGCGAGG	PRKG2	ENSG00000138669	1.27306988851105	[]	[]	1	hSpCas9	negative selection	3548016
81204690	81204713	4	-	26780180	A375	viability (Avana lentiCRISPRv2)	GGTCTCTCTCCATAGCAGGAGGG	PRKG2	ENSG00000138669	0.726483212322589	[]	[]	1	hSpCas9	negative selection	3548017
81204776	81204799	4	-	26780180	A375	viability (Avana lentiCRISPRv2)	GATGTGGTGCATATGCAGGGAGG	PRKG2	ENSG00000138669	4.43293329256393	[]	[]	7	hSpCas9	negative selection	3548018
81204837	81204860	4	-	26780180	A375	viability (Avana lentiGuide)	GGCCATTGCTGAACTCACAGAGG	PRKG2	ENSG00000138669	-3.90701665094538	[]	[]	-6	hSpCas9	negative selection	3656673
81204858	81204881	4	-	26780180	A375	viability (Avana lentiGuide)	GCAGCTGTCGAAGCAGACTGTGG	PRKG2	ENSG00000138669	6.52441037316491	[]	[]	5	hSpCas9	negative selection	3656674
81153679	81153702	4	-	26780180	A375	viability (Avana lentiGuide)	TTACATCATTAGAGAGGGCGAGG	PRKG2	ENSG00000138669	-2.27792439782419	[]	[]	-4	hSpCas9	negative selection	3656675
81204690	81204713	4	-	26780180	A375	viability (Avana lentiGuide)	GGTCTCTCTCCATAGCAGGAGGG	PRKG2	ENSG00000138669	-5.78304153767336	[]	[]	-8	hSpCas9	negative selection	3656676
81204776	81204799	4	-	26780180	A375	viability (Avana lentiGuide)	GATGTGGTGCATATGCAGGGAGG	PRKG2	ENSG00000138669	4.20841492848335	[]	[]	4	hSpCas9	negative selection	3656677
81204837	81204860	4	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGCCATTGCTGAACTCACAGAGG	PRKG2	ENSG00000138669	-0.4962270505298745	[5]	[4,2]	-6	hSpCas9	positive selection	3765280
81204858	81204881	4	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCAGCTGTCGAAGCAGACTGTGG	PRKG2	ENSG00000138669	0.08918167624077034	[4]	[5,3]	2	hSpCas9	positive selection	3765281
81153679	81153702	4	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TTACATCATTAGAGAGGGCGAGG	PRKG2	ENSG00000138669	0.017729620897918352	[5]	[6,4]	0	hSpCas9	positive selection	3765282
81204690	81204713	4	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGTCTCTCTCCATAGCAGGAGGG	PRKG2	ENSG00000138669	0.08621423799918129	[5]	[5,4]	2	hSpCas9	positive selection	3765283
81204776	81204799	4	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GATGTGGTGCATATGCAGGGAGG	PRKG2	ENSG00000138669	0.22641286468674812	[5]	[6,6]	6	hSpCas9	positive selection	3765284
81204837	81204860	4	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGCCATTGCTGAACTCACAGAGG	PRKG2	ENSG00000138669	0.2732435758581249	[6]	[7,6]	7	hSpCas9	positive selection	3873887
81204858	81204881	4	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCAGCTGTCGAAGCAGACTGTGG	PRKG2	ENSG00000138669	-2.245739930195185	[4]	[0,0]	-9	hSpCas9	positive selection	3873888
81153679	81153702	4	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TTACATCATTAGAGAGGGCGAGG	PRKG2	ENSG00000138669	-0.4048710482869795	[4]	[4,0]	-5	hSpCas9	positive selection	3873889
81204690	81204713	4	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGTCTCTCTCCATAGCAGGAGGG	PRKG2	ENSG00000138669	0.2309066796722069	[5]	[4,5]	6	hSpCas9	positive selection	3873890
81204776	81204799	4	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GATGTGGTGCATATGCAGGGAGG	PRKG2	ENSG00000138669	0.19862233352236452	[6]	[6,6]	5	hSpCas9	positive selection	3873891
81204635	81204657	4	+	27760321	OCIAML3	viability	TTGTTCAGGTCATAGGTCCGGG	PRKG2	ENSG00000138669	0.8299253020751469	[675,686]	[790,1159]	8	hSpCas9	negative selection	4430665
81204635	81204657	4	+	27760321	OCIAML2	viability	TTGTTCAGGTCATAGGTCCGGG	PRKG2	ENSG00000138669	0.07392731156370624	[675,686]	[538,639]	0	hSpCas9	negative selection	4514128
81204635	81204657	4	+	27760321	MV411	viability	TTGTTCAGGTCATAGGTCCGGG	PRKG2	ENSG00000138669	0.7909634588839669	[675,686]	[1014,429]	6	hSpCas9	negative selection	4597591
81204635	81204657	4	+	27760321	HL60	viability	TTGTTCAGGTCATAGGTCCGGG	PRKG2	ENSG00000138669	0.34967955277912366	[675,686]	[701,722]	4	hSpCas9	negative selection	4681054
81204635	81204657	4	+	27760321	HT1080	viability	TTGTTCAGGTCATAGGTCCGGG	PRKG2	ENSG00000138669	0.18294646113767588	[686,535]	[350,194]	0	hSpCas9	negative selection	4764517
81204635	81204657	4	+	27760321	HT29	viability after 7 days	TTGTTCAGGTCATAGGTCCGGG	PRKG2	ENSG00000138669	-0.3225669540795865	[686,535]	[480,783,599]	-4	hSpCas9	negative selection	4847980
81204635	81204657	4	+	27760321	HT29	viability after 25 days	TTGTTCAGGTCATAGGTCCGGG	PRKG2	ENSG00000138669	-0.05729419661374857	[686,535]	[561,689,779]	0	hSpCas9	negative selection	4931443
81204635	81204657	4	+	27760321	HT29	viability after 22 days	TTGTTCAGGTCATAGGTCCGGG	PRKG2	ENSG00000138669	-0.5261468384532416	[686,535]	[378,673,421]	-5	hSpCas9	negative selection	5014906
81204635	81204657	4	+	27760321	HT29	viability after 19 days	TTGTTCAGGTCATAGGTCCGGG	PRKG2	ENSG00000138669	-0.015784325778451458	[686,535]	[539,455,1048]	0	hSpCas9	negative selection	5098369
81204635	81204657	4	+	27760321	HT29	viability after 16 days	TTGTTCAGGTCATAGGTCCGGG	PRKG2	ENSG00000138669	-0.21990795443142352	[686,535]	[824,494,466]	-2	hSpCas9	negative selection	5181832
81204635	81204657	4	+	27760321	HT29	viability after 13 days	TTGTTCAGGTCATAGGTCCGGG	PRKG2	ENSG00000138669	-0.35626637816778534	[686,535]	[533,617,512]	-4	hSpCas9	negative selection	5265295
81204635	81204657	4	+	27760321	HT29	viability after 10 days	TTGTTCAGGTCATAGGTCCGGG	PRKG2	ENSG00000138669	-0.385201156334967	[686,535]	[522,739,496]	-5	hSpCas9	negative selection	5348758
81204635	81204657	4	+	27760321	MOLM13	viability	TTGTTCAGGTCATAGGTCCGGG	PRKG2	ENSG00000138669	-0.6652743548556749	[675,686]	[210,270]	-4	hSpCas9	negative selection	5432221
81214785	81214808	4	+	27661255	K562	viability	GAACAGCACAAGCAAGAGACCGG	PRKG2	ENSG00000138669	0.16307374339123482	[1085,1156]	[1036,971]	5	dCas9-KRAB	negative selection	5504203
81214790	81214813	4	+	27661255	K562	viability	GCACAAGCAAGAGACCGGCTGGG	PRKG2	ENSG00000138669	0.10163157560953978	[952,865]	[856,715]	3	dCas9-KRAB	negative selection	5504204
81215106	81215129	4	+	27661255	K562	viability	GGCTGCCGGCTCAGTCGCTCCGG	PRKG2	ENSG00000138669	0.1854440907329592	[422,465]	[408,397]	6	dCas9-KRAB	negative selection	5504205
81148879	81148902	4	+	27869803	HPAFII	viability after 27 days	CTCACTCTCGATCTATAACCAGG	PRKG2	ENSG00000138669	0.2738573153452606	[500]	[234,387,NaN]	2	hSpCas9	negative selection	9589034
81153679	81153702	4	-	27869803	HPAFII	viability after 27 days	TTACATCATTAGAGAGGGCGAGG	PRKG2	ENSG00000138669	0.38000568424027403	[231]	[149,165,NaN]	3	hSpCas9	negative selection	9589037
81204691	81204714	4	-	27869803	HPAFII	viability after 27 days	TGGTCTCTCTCCATAGCAGGAGG	PRKG2	ENSG00000138669	0.611311441689579	[132]	[114,99,NaN]	5	hSpCas9	negative selection	9589039
81148879	81148902	4	+	27869803	HPAFII	viability after 15 days	CTCACTCTCGATCTATAACCAGG	PRKG2	ENSG00000138669	-0.13659627649831496	[500]	[474,498,NaN]	-2	hSpCas9	negative selection	9671483
81153679	81153702	4	-	27869803	HPAFII	viability after 15 days	TTACATCATTAGAGAGGGCGAGG	PRKG2	ENSG00000138669	0.22451336077423492	[231]	[516,150,NaN]	2	hSpCas9	negative selection	9671486
81204691	81204714	4	-	27869803	HPAFII	viability after 15 days	TGGTCTCTCTCCATAGCAGGAGG	PRKG2	ENSG00000138669	0.6121860871351317	[132]	[318,155,NaN]	7	hSpCas9	negative selection	9671488
81148879	81148902	4	+	27869803	ASPC1	viability after 36 days	CTCACTCTCGATCTATAACCAGG	PRKG2	ENSG00000138669	0.6491805977574321	[928]	[302,750,454]	6	hSpCas9	negative selection	9753932
81153679	81153702	4	-	27869803	ASPC1	viability after 36 days	TTACATCATTAGAGAGGGCGAGG	PRKG2	ENSG00000138669	0.3077480014208966	[647]	[389,304,179]	3	hSpCas9	negative selection	9753935
81204691	81204714	4	-	27869803	ASPC1	viability after 36 days	TGGTCTCTCTCCATAGCAGGAGG	PRKG2	ENSG00000138669	0.9011209621397009	[500]	[522,54,400]	8	hSpCas9	negative selection	9753937
81148879	81148902	4	+	27869803	PATU8988S	viability after 35 days	CTCACTCTCGATCTATAACCAGG	PRKG2	ENSG00000138669	0.8529411443315539	[884]	[548,738,NaN]	8	hSpCas9	negative selection	9836381
81153679	81153702	4	-	27869803	PATU8988S	viability after 35 days	TTACATCATTAGAGAGGGCGAGG	PRKG2	ENSG00000138669	0.3856424249355952	[604]	[244,391,NaN]	4	hSpCas9	negative selection	9836384
81204691	81204714	4	-	27869803	PATU8988S	viability after 35 days	TGGTCTCTCTCCATAGCAGGAGG	PRKG2	ENSG00000138669	-0.22903419064549538	[489]	[114,221,NaN]	-2	hSpCas9	negative selection	9836386
81148879	81148902	4	+	27869803	PATU8988S	viability after 31 days	CTCACTCTCGATCTATAACCAGG	PRKG2	ENSG00000138669	0.8380304799853439	[884]	[559,720,NaN]	8	hSpCas9	negative selection	9918830
81153679	81153702	4	-	27869803	PATU8988S	viability after 31 days	TTACATCATTAGAGAGGGCGAGG	PRKG2	ENSG00000138669	0.4478980246573018	[604]	[248,430,NaN]	5	hSpCas9	negative selection	9918833
81204691	81204714	4	-	27869803	PATU8988S	viability after 31 days	TGGTCTCTCTCCATAGCAGGAGG	PRKG2	ENSG00000138669	-0.35408778536543795	[489]	[63,265,NaN]	-4	hSpCas9	negative selection	9918835
81148879	81148902	4	+	27869803	HPAFII	viability after 35 days	CTCACTCTCGATCTATAACCAGG	PRKG2	ENSG00000138669	0.7551418657882509	[500]	[222,658,NaN]	5	hSpCas9	negative selection	10001279
81153679	81153702	4	-	27869803	HPAFII	viability after 35 days	TTACATCATTAGAGAGGGCGAGG	PRKG2	ENSG00000138669	0.24054398671521848	[231]	[126,151,NaN]	1	hSpCas9	negative selection	10001282
81204691	81204714	4	-	27869803	HPAFII	viability after 35 days	TGGTCTCTCTCCATAGCAGGAGG	PRKG2	ENSG00000138669	0.6396389327640362	[132]	[134,70,NaN]	4	hSpCas9	negative selection	10001284
81148879	81148902	4	+	27869803	HPAFII	viability after 31 days	CTCACTCTCGATCTATAACCAGG	PRKG2	ENSG00000138669	0.17878586911383954	[500]	[178,469,NaN]	1	hSpCas9	negative selection	10083728
81153679	81153702	4	-	27869803	HPAFII	viability after 31 days	TTACATCATTAGAGAGGGCGAGG	PRKG2	ENSG00000138669	0.4763174229021252	[231]	[239,116,NaN]	3	hSpCas9	negative selection	10083731
81204691	81204714	4	-	27869803	HPAFII	viability after 31 days	TGGTCTCTCTCCATAGCAGGAGG	PRKG2	ENSG00000138669	0.7412325630093568	[132]	[141,105,NaN]	5	hSpCas9	negative selection	10083733
81204927	81204950	4	-	28162770	P31FUJ	viability	GGAGAGAGAGTTGAGGAGGAAGG	PRKG2	ENSG00000138669	-3.1869985148012536	[123]	[15]	-9	hSpCas9	negative selection	10217195
81204907	81204930	4	-	28162770	P31FUJ	viability	AGGATGCTGAGATCCAGGAGCGG	PRKG2	ENSG00000138669	-0.2597692520146479	[161]	[158]	-2	hSpCas9	negative selection	10217196
81204776	81204799	4	-	28162770	P31FUJ	viability	GATGTGGTGCATATGCAGGGAGG	PRKG2	ENSG00000138669	0.21880990976361947	[184]	[252]	2	hSpCas9	negative selection	10217197
81204711	81204734	4	+	28162770	P31FUJ	viability	CCAATCCAGAGGTCTTCCGGTGG	PRKG2	ENSG00000138669	0.3034981776071892	[401]	[582]	3	hSpCas9	negative selection	10217198
81204700	81204723	4	+	28162770	P31FUJ	viability	ATGGAGAGAGACCAATCCAGAGG	PRKG2	ENSG00000138669	-0.5217384736909295	[280]	[229]	-4	hSpCas9	negative selection	10217199
81142877	81142900	4	-	28162770	P31FUJ	viability	GATTCAGCTGAAGGAGAAGGTGG	PRKG2	ENSG00000138669	-0.469605068674993	[217]	[184]	-4	hSpCas9	negative selection	10217200
81105913	81105936	4	+	28162770	P31FUJ	viability	GGTCAACCCCAGAAAAGGGTGGG	PRKG2	ENSG00000138669	0.7265558110882755	[17]	[34]	8	hSpCas9	negative selection	10217201
81105835	81105858	4	-	28162770	P31FUJ	viability	GAAGATAACACGACGACCTGAGG	PRKG2	ENSG00000138669	0.30555988344463847	[408]	[593]	3	hSpCas9	negative selection	10217202
81204927	81204950	4	-	28162770	TF1	viability	GGAGAGAGAGTTGAGGAGGAAGG	PRKG2	ENSG00000138669	NaN	[NaN]	[70]	1	hSpCas9	negative selection	10386561
81204907	81204930	4	-	28162770	TF1	viability	AGGATGCTGAGATCCAGGAGCGG	PRKG2	ENSG00000138669	NaN	[NaN]	[165]	1	hSpCas9	negative selection	10386562
81204776	81204799	4	-	28162770	TF1	viability	GATGTGGTGCATATGCAGGGAGG	PRKG2	ENSG00000138669	NaN	[NaN]	[253]	1	hSpCas9	negative selection	10386563
81204711	81204734	4	+	28162770	TF1	viability	CCAATCCAGAGGTCTTCCGGTGG	PRKG2	ENSG00000138669	NaN	[NaN]	[195]	1	hSpCas9	negative selection	10386564
81204700	81204723	4	+	28162770	TF1	viability	ATGGAGAGAGACCAATCCAGAGG	PRKG2	ENSG00000138669	NaN	[NaN]	[78]	1	hSpCas9	negative selection	10386565
81142877	81142900	4	-	28162770	TF1	viability	GATTCAGCTGAAGGAGAAGGTGG	PRKG2	ENSG00000138669	NaN	[NaN]	[95]	1	hSpCas9	negative selection	10386566
81105913	81105936	4	+	28162770	TF1	viability	GGTCAACCCCAGAAAAGGGTGGG	PRKG2	ENSG00000138669	NaN	[NaN]	[85]	1	hSpCas9	negative selection	10386567
81105835	81105858	4	-	28162770	TF1	viability	GAAGATAACACGACGACCTGAGG	PRKG2	ENSG00000138669	NaN	[NaN]	[442]	1	hSpCas9	negative selection	10386568
81204927	81204950	4	-	28162770	SKM1	viability	GGAGAGAGAGTTGAGGAGGAAGG	PRKG2	ENSG00000138669	-2.968843086351277	[30]	[6]	-9	hSpCas9	negative selection	10555927
81204907	81204930	4	-	28162770	SKM1	viability	AGGATGCTGAGATCCAGGAGCGG	PRKG2	ENSG00000138669	-0.7130673264688414	[50]	[54]	-5	hSpCas9	negative selection	10555928
81204776	81204799	4	-	28162770	SKM1	viability	GATGTGGTGCATATGCAGGGAGG	PRKG2	ENSG00000138669	0.4438923619510288	[41]	[100]	4	hSpCas9	negative selection	10555929
81204711	81204734	4	+	28162770	SKM1	viability	CCAATCCAGAGGTCTTCCGGTGG	PRKG2	ENSG00000138669	0.8998964480552589	[76]	[253]	8	hSpCas9	negative selection	10555930
81204700	81204723	4	+	28162770	SKM1	viability	ATGGAGAGAGACCAATCCAGAGG	PRKG2	ENSG00000138669	-0.7017074643042935	[91]	[99]	-5	hSpCas9	negative selection	10555931
81142877	81142900	4	-	28162770	SKM1	viability	GATTCAGCTGAAGGAGAAGGTGG	PRKG2	ENSG00000138669	0.4124635556150176	[33]	[79]	4	hSpCas9	negative selection	10555932
81105913	81105936	4	+	28162770	SKM1	viability	GGTCAACCCCAGAAAAGGGTGGG	PRKG2	ENSG00000138669	-3.991926699464318	[8]	[0]	-9	hSpCas9	negative selection	10555933
81105835	81105858	4	-	28162770	SKM1	viability	GAAGATAACACGACGACCTGAGG	PRKG2	ENSG00000138669	-0.1339457043367458	[107]	[173]	-1	hSpCas9	negative selection	10555934
81204927	81204950	4	-	28162770	SKM1	viability	GGAGAGAGAGTTGAGGAGGAAGG	PRKG2	ENSG00000138669	-2.968843086351277	[30]	[6]	-9	hSpCas9	negative selection	10725293
81204907	81204930	4	-	28162770	SKM1	viability	AGGATGCTGAGATCCAGGAGCGG	PRKG2	ENSG00000138669	-0.7130673264688414	[50]	[54]	-5	hSpCas9	negative selection	10725294
81204776	81204799	4	-	28162770	SKM1	viability	GATGTGGTGCATATGCAGGGAGG	PRKG2	ENSG00000138669	0.4438923619510288	[41]	[100]	4	hSpCas9	negative selection	10725295
81204711	81204734	4	+	28162770	SKM1	viability	CCAATCCAGAGGTCTTCCGGTGG	PRKG2	ENSG00000138669	0.8998964480552589	[76]	[253]	8	hSpCas9	negative selection	10725296
81204700	81204723	4	+	28162770	SKM1	viability	ATGGAGAGAGACCAATCCAGAGG	PRKG2	ENSG00000138669	-0.7017074643042935	[91]	[99]	-5	hSpCas9	negative selection	10725297
81142877	81142900	4	-	28162770	SKM1	viability	GATTCAGCTGAAGGAGAAGGTGG	PRKG2	ENSG00000138669	0.4124635556150176	[33]	[79]	4	hSpCas9	negative selection	10725298
81105913	81105936	4	+	28162770	SKM1	viability	GGTCAACCCCAGAAAAGGGTGGG	PRKG2	ENSG00000138669	-3.991926699464318	[8]	[0]	-9	hSpCas9	negative selection	10725299
81105835	81105858	4	-	28162770	SKM1	viability	GAAGATAACACGACGACCTGAGG	PRKG2	ENSG00000138669	-0.1339457043367458	[107]	[173]	-1	hSpCas9	negative selection	10725300
81204927	81204950	4	-	28162770	PL21	viability	GGAGAGAGAGTTGAGGAGGAAGG	PRKG2	ENSG00000138669	-2.072878879917096	[115]	[11]	-8	hSpCas9	negative selection	10894659
81204907	81204930	4	-	28162770	PL21	viability	AGGATGCTGAGATCCAGGAGCGG	PRKG2	ENSG00000138669	0.2814397165911684	[137]	[72]	2	hSpCas9	negative selection	10894660
81204776	81204799	4	-	28162770	PL21	viability	GATGTGGTGCATATGCAGGGAGG	PRKG2	ENSG00000138669	-0.38482288623183614	[209]	[69]	-3	hSpCas9	negative selection	10894661
81204711	81204734	4	+	28162770	PL21	viability	CCAATCCAGAGGTCTTCCGGTGG	PRKG2	ENSG00000138669	1.2493525889679964	[316]	[327]	8	hSpCas9	negative selection	10894662
81204700	81204723	4	+	28162770	PL21	viability	ATGGAGAGAGACCAATCCAGAGG	PRKG2	ENSG00000138669	-0.12425252034952328	[292]	[116]	-1	hSpCas9	negative selection	10894663
81142877	81142900	4	-	28162770	PL21	viability	GATTCAGCTGAAGGAGAAGGTGG	PRKG2	ENSG00000138669	0.08466239706938405	[103]	[47]	0	hSpCas9	negative selection	10894664
81105913	81105936	4	+	28162770	PL21	viability	GGTCAACCCCAGAAAAGGGTGGG	PRKG2	ENSG00000138669	2.984410923433883	[26]	[92]	9	hSpCas9	negative selection	10894665
81105835	81105858	4	-	28162770	PL21	viability	GAAGATAACACGACGACCTGAGG	PRKG2	ENSG00000138669	0.6055269437344447	[224]	[148]	5	hSpCas9	negative selection	10894666
81204927	81204950	4	-	28162770	P31FUJ	viability	GGAGAGAGAGTTGAGGAGGAAGG	PRKG2	ENSG00000138669	-3.1869985148012536	[123]	[15]	-9	hSpCas9	negative selection	11064025
81204907	81204930	4	-	28162770	P31FUJ	viability	AGGATGCTGAGATCCAGGAGCGG	PRKG2	ENSG00000138669	-0.2597692520146479	[161]	[158]	-2	hSpCas9	negative selection	11064026
81204776	81204799	4	-	28162770	P31FUJ	viability	GATGTGGTGCATATGCAGGGAGG	PRKG2	ENSG00000138669	0.21880990976361947	[184]	[252]	2	hSpCas9	negative selection	11064027
81204711	81204734	4	+	28162770	P31FUJ	viability	CCAATCCAGAGGTCTTCCGGTGG	PRKG2	ENSG00000138669	0.3034981776071892	[401]	[582]	3	hSpCas9	negative selection	11064028
81204700	81204723	4	+	28162770	P31FUJ	viability	ATGGAGAGAGACCAATCCAGAGG	PRKG2	ENSG00000138669	-0.5217384736909295	[280]	[229]	-4	hSpCas9	negative selection	11064029
81142877	81142900	4	-	28162770	P31FUJ	viability	GATTCAGCTGAAGGAGAAGGTGG	PRKG2	ENSG00000138669	-0.469605068674993	[217]	[184]	-4	hSpCas9	negative selection	11064030
81105913	81105936	4	+	28162770	P31FUJ	viability	GGTCAACCCCAGAAAAGGGTGGG	PRKG2	ENSG00000138669	0.7265558110882755	[17]	[34]	8	hSpCas9	negative selection	11064031
81105835	81105858	4	-	28162770	P31FUJ	viability	GAAGATAACACGACGACCTGAGG	PRKG2	ENSG00000138669	0.30555988344463847	[408]	[593]	3	hSpCas9	negative selection	11064032
81204927	81204950	4	-	28162770	OCIAML5	viability	GGAGAGAGAGTTGAGGAGGAAGG	PRKG2	ENSG00000138669	-2.9489281101165856	[76]	[17]	-8	hSpCas9	negative selection	11233391
81204907	81204930	4	-	28162770	OCIAML5	viability	AGGATGCTGAGATCCAGGAGCGG	PRKG2	ENSG00000138669	0.45857571647685025	[76]	[190]	4	hSpCas9	negative selection	11233392
81204776	81204799	4	-	28162770	OCIAML5	viability	GATGTGGTGCATATGCAGGGAGG	PRKG2	ENSG00000138669	-1.0100189306402334	[134]	[120]	-6	hSpCas9	negative selection	11233393
81204711	81204734	4	+	28162770	OCIAML5	viability	CCAATCCAGAGGTCTTCCGGTGG	PRKG2	ENSG00000138669	0.3116318562134278	[128]	[288]	2	hSpCas9	negative selection	11233394
81204700	81204723	4	+	28162770	OCIAML5	viability	ATGGAGAGAGACCAATCCAGAGG	PRKG2	ENSG00000138669	-0.18351743986986585	[94]	[150]	-1	hSpCas9	negative selection	11233395
81142877	81142900	4	-	28162770	OCIAML5	viability	GATTCAGCTGAAGGAGAAGGTGG	PRKG2	ENSG00000138669	0.5650909802892163	[84]	[226]	5	hSpCas9	negative selection	11233396
81105913	81105936	4	+	28162770	OCIAML5	viability	GGTCAACCCCAGAAAAGGGTGGG	PRKG2	ENSG00000138669	-0.2057035254786972	[22]	[35]	-1	hSpCas9	negative selection	11233397
81105835	81105858	4	-	28162770	OCIAML5	viability	GAAGATAACACGACGACCTGAGG	PRKG2	ENSG00000138669	0.09064020408849349	[243]	[468]	0	hSpCas9	negative selection	11233398
81204927	81204950	4	-	28162770	EOL1	viability	GGAGAGAGAGTTGAGGAGGAAGG	PRKG2	ENSG00000138669	-2.430294945789563	[132]	[12]	-8	hSpCas9	negative selection	11402757
81204907	81204930	4	-	28162770	EOL1	viability	AGGATGCTGAGATCCAGGAGCGG	PRKG2	ENSG00000138669	0.8381330197530615	[257]	[242]	7	hSpCas9	negative selection	11402758
81204776	81204799	4	-	28162770	EOL1	viability	GATGTGGTGCATATGCAGGGAGG	PRKG2	ENSG00000138669	0.5333570142460585	[319]	[243]	5	hSpCas9	negative selection	11402759
81204711	81204734	4	+	28162770	EOL1	viability	CCAATCCAGAGGTCTTCCGGTGG	PRKG2	ENSG00000138669	-0.6088844285105397	[604]	[208]	-4	hSpCas9	negative selection	11402760
81204700	81204723	4	+	28162770	EOL1	viability	ATGGAGAGAGACCAATCCAGAGG	PRKG2	ENSG00000138669	-0.3476272881197282	[569]	[235]	-3	hSpCas9	negative selection	11402761
81142877	81142900	4	-	28162770	EOL1	viability	GATTCAGCTGAAGGAGAAGGTGG	PRKG2	ENSG00000138669	-0.06357812814117358	[120]	[60]	0	hSpCas9	negative selection	11402762
81105913	81105936	4	+	28162770	EOL1	viability	GGTCAACCCCAGAAAAGGGTGGG	PRKG2	ENSG00000138669	-1.699943093337259	[36]	[5]	-8	hSpCas9	negative selection	11402763
81105835	81105858	4	-	28162770	EOL1	viability	GAAGATAACACGACGACCTGAGG	PRKG2	ENSG00000138669	1.2364917778852746	[347]	[431]	8	hSpCas9	negative selection	11402764
81204927	81204950	4	-	28162770	MOLM13	viability	GGAGAGAGAGTTGAGGAGGAAGG	PRKG2	ENSG00000138669	-6.671661970854215	[140]	[0]	-9	hSpCas9	negative selection	11572123
81204907	81204930	4	-	28162770	MOLM13	viability	AGGATGCTGAGATCCAGGAGCGG	PRKG2	ENSG00000138669	0.5320197189642943	[219]	[229]	4	hSpCas9	negative selection	11572124
81204776	81204799	4	-	28162770	MOLM13	viability	GATGTGGTGCATATGCAGGGAGG	PRKG2	ENSG00000138669	1.0945856405749166	[317]	[490]	8	hSpCas9	negative selection	11572125
81204711	81204734	4	+	28162770	MOLM13	viability	CCAATCCAGAGGTCTTCCGGTGG	PRKG2	ENSG00000138669	0.37167406628527555	[433]	[405]	2	hSpCas9	negative selection	11572126
81204700	81204723	4	+	28162770	MOLM13	viability	ATGGAGAGAGACCAATCCAGAGG	PRKG2	ENSG00000138669	-1.1813538705088402	[435]	[138]	-6	hSpCas9	negative selection	11572127
81142877	81142900	4	-	28162770	MOLM13	viability	GATTCAGCTGAAGGAGAAGGTGG	PRKG2	ENSG00000138669	0.008457762907281619	[153]	[111]	0	hSpCas9	negative selection	11572128
81105913	81105936	4	+	28162770	MOLM13	viability	GGTCAACCCCAGAAAAGGGTGGG	PRKG2	ENSG00000138669	-4.6195734597057605	[33]	[0]	-9	hSpCas9	negative selection	11572129
81105835	81105858	4	-	28162770	MOLM13	viability	GAAGATAACACGACGACCTGAGG	PRKG2	ENSG00000138669	0.7553079460053318	[439]	[536]	6	hSpCas9	negative selection	11572130
81204927	81204950	4	-	28162770	HEL	viability	GGAGAGAGAGTTGAGGAGGAAGG	PRKG2	ENSG00000138669	-6.412543603500833	[132]	[0]	-9	hSpCas9	negative selection	11741489
81204907	81204930	4	-	28162770	HEL	viability	AGGATGCTGAGATCCAGGAGCGG	PRKG2	ENSG00000138669	0.6490526059325594	[227]	[228]	5	hSpCas9	negative selection	11741490
81204776	81204799	4	-	28162770	HEL	viability	GATGTGGTGCATATGCAGGGAGG	PRKG2	ENSG00000138669	0.18674465849865535	[261]	[190]	1	hSpCas9	negative selection	11741491
81204711	81204734	4	+	28162770	HEL	viability	CCAATCCAGAGGTCTTCCGGTGG	PRKG2	ENSG00000138669	0.5694544059651252	[423]	[402]	5	hSpCas9	negative selection	11741492
81204700	81204723	4	+	28162770	HEL	viability	ATGGAGAGAGACCAATCCAGAGG	PRKG2	ENSG00000138669	-0.966588217119999	[417]	[136]	-5	hSpCas9	negative selection	11741493
81142877	81142900	4	-	28162770	HEL	viability	GATTCAGCTGAAGGAGAAGGTGG	PRKG2	ENSG00000138669	0.1732535486991369	[143]	[103]	1	hSpCas9	negative selection	11741494
81105913	81105936	4	+	28162770	HEL	viability	GGTCAACCCCAGAAAAGGGTGGG	PRKG2	ENSG00000138669	0.5114942987221043	[22]	[20]	4	hSpCas9	negative selection	11741495
81105835	81105858	4	-	28162770	HEL	viability	GAAGATAACACGACGACCTGAGG	PRKG2	ENSG00000138669	0.8177252434462462	[410]	[463]	7	hSpCas9	negative selection	11741496
81204927	81204950	4	-	28162770	MV411	viability	GGAGAGAGAGTTGAGGAGGAAGG	PRKG2	ENSG00000138669	-3.892113801616018	[140]	[7]	-9	hSpCas9	negative selection	11910855
81204907	81204930	4	-	28162770	MV411	viability	AGGATGCTGAGATCCAGGAGCGG	PRKG2	ENSG00000138669	1.10176009558714	[176]	[319]	8	hSpCas9	negative selection	11910856
81204776	81204799	4	-	28162770	MV411	viability	GATGTGGTGCATATGCAGGGAGG	PRKG2	ENSG00000138669	0.17492505099840747	[203]	[193]	1	hSpCas9	negative selection	11910857
81204711	81204734	4	+	28162770	MV411	viability	CCAATCCAGAGGTCTTCCGGTGG	PRKG2	ENSG00000138669	0.6948965277539964	[307]	[419]	6	hSpCas9	negative selection	11910858
81204700	81204723	4	+	28162770	MV411	viability	ATGGAGAGAGACCAATCCAGAGG	PRKG2	ENSG00000138669	-0.24367664922299404	[304]	[216]	-2	hSpCas9	negative selection	11910859
81142877	81142900	4	-	28162770	MV411	viability	GATTCAGCTGAAGGAGAAGGTGG	PRKG2	ENSG00000138669	0.18094213899586842	[110]	[105]	1	hSpCas9	negative selection	11910860
81105913	81105936	4	+	28162770	MV411	viability	GGTCAACCCCAGAAAAGGGTGGG	PRKG2	ENSG00000138669	0.7620107236125335	[20]	[29]	7	hSpCas9	negative selection	11910861
81105835	81105858	4	-	28162770	MV411	viability	GAAGATAACACGACGACCTGAGG	PRKG2	ENSG00000138669	0.5937891196093554	[327]	[416]	5	hSpCas9	negative selection	11910862
81204927	81204950	4	-	28162770	MONOMAC1	viability	GGAGAGAGAGTTGAGGAGGAAGG	PRKG2	ENSG00000138669	-0.8054583206046988	[92]	[60]	-6	hSpCas9	negative selection	12080221
81204907	81204930	4	-	28162770	MONOMAC1	viability	AGGATGCTGAGATCCAGGAGCGG	PRKG2	ENSG00000138669	0.31044690098388533	[101]	[144]	3	hSpCas9	negative selection	12080222
81204776	81204799	4	-	28162770	MONOMAC1	viability	GATGTGGTGCATATGCAGGGAGG	PRKG2	ENSG00000138669	0.6647658590204268	[103]	[188]	6	hSpCas9	negative selection	12080223
81204711	81204734	4	+	28162770	MONOMAC1	viability	CCAATCCAGAGGTCTTCCGGTGG	PRKG2	ENSG00000138669	0.4214003582126905	[212]	[326]	4	hSpCas9	negative selection	12080224
81204700	81204723	4	+	28162770	MONOMAC1	viability	ATGGAGAGAGACCAATCCAGAGG	PRKG2	ENSG00000138669	-0.47655937568191636	[175]	[144]	-4	hSpCas9	negative selection	12080225
81142877	81142900	4	-	28162770	MONOMAC1	viability	GATTCAGCTGAAGGAGAAGGTGG	PRKG2	ENSG00000138669	0.7623211684431004	[53]	[104]	7	hSpCas9	negative selection	12080226
81105913	81105936	4	+	28162770	MONOMAC1	viability	GGTCAACCCCAGAAAAGGGTGGG	PRKG2	ENSG00000138669	-0.46007125289334727	[17]	[14]	-4	hSpCas9	negative selection	12080227
81105835	81105858	4	-	28162770	MONOMAC1	viability	GAAGATAACACGACGACCTGAGG	PRKG2	ENSG00000138669	0.5399287471066527	[173]	[289]	5	hSpCas9	negative selection	12080228
81204927	81204950	4	-	28162770	OCIAML2	viability	GGAGAGAGAGTTGAGGAGGAAGG	PRKG2	ENSG00000138669	-5.640554826684474	[17]	[1]	-9	hSpCas9	negative selection	12249587
81204907	81204930	4	-	28162770	OCIAML2	viability	AGGATGCTGAGATCCAGGAGCGG	PRKG2	ENSG00000138669	0.9444076740366825	[20]	[223]	8	hSpCas9	negative selection	12249588
81204776	81204799	4	-	28162770	OCIAML2	viability	GATGTGGTGCATATGCAGGGAGG	PRKG2	ENSG00000138669	0.144834763876339	[38]	[238]	1	hSpCas9	negative selection	12249589
81204711	81204734	4	+	28162770	OCIAML2	viability	CCAATCCAGAGGTCTTCCGGTGG	PRKG2	ENSG00000138669	0.7332425081234887	[55]	[515]	7	hSpCas9	negative selection	12249590
81204700	81204723	4	+	28162770	OCIAML2	viability	ATGGAGAGAGACCAATCCAGAGG	PRKG2	ENSG00000138669	-0.5546940900306357	[52]	[199]	-4	hSpCas9	negative selection	12249591
81142877	81142900	4	-	28162770	OCIAML2	viability	GATTCAGCTGAAGGAGAAGGTGG	PRKG2	ENSG00000138669	1.4634822391013815	[13]	[213]	9	hSpCas9	negative selection	12249592
81105913	81105936	4	+	28162770	OCIAML2	viability	GGTCAACCCCAGAAAAGGGTGGG	PRKG2	ENSG00000138669	-3.0555923259633175	[5]	[3]	-9	hSpCas9	negative selection	12249593
81105835	81105858	4	-	28162770	OCIAML2	viability	GAAGATAACACGACGACCTGAGG	PRKG2	ENSG00000138669	0.38512192137455636	[66]	[484]	3	hSpCas9	negative selection	12249594
81204927	81204950	4	-	28162770	OCIAML3	viability	GGAGAGAGAGTTGAGGAGGAAGG	PRKG2	ENSG00000138669	-1.3402510480783802	[25]	[30]	-7	hSpCas9	negative selection	12418953
81204907	81204930	4	-	28162770	OCIAML3	viability	AGGATGCTGAGATCCAGGAGCGG	PRKG2	ENSG00000138669	0.020101206056509474	[48]	[149]	0	hSpCas9	negative selection	12418954
81204776	81204799	4	-	28162770	OCIAML3	viability	GATGTGGTGCATATGCAGGGAGG	PRKG2	ENSG00000138669	0.979639547169159	[63]	[380]	8	hSpCas9	negative selection	12418955
81204711	81204734	4	+	28162770	OCIAML3	viability	CCAATCCAGAGGTCTTCCGGTGG	PRKG2	ENSG00000138669	-0.9015166752985618	[111]	[180]	-6	hSpCas9	negative selection	12418956
81204700	81204723	4	+	28162770	OCIAML3	viability	ATGGAGAGAGACCAATCCAGAGG	PRKG2	ENSG00000138669	0.09901460625444602	[89]	[290]	0	hSpCas9	negative selection	12418957
81142877	81142900	4	-	28162770	OCIAML3	viability	GATTCAGCTGAAGGAGAAGGTGG	PRKG2	ENSG00000138669	0.03986446087793949	[28]	[89]	0	hSpCas9	negative selection	12418958
81105913	81105936	4	+	28162770	OCIAML3	viability	GGTCAACCCCAGAAAAGGGTGGG	PRKG2	ENSG00000138669	-2.5940076403241634	[11]	[5]	-9	hSpCas9	negative selection	12418959
81105835	81105858	4	-	28162770	OCIAML3	viability	GAAGATAACACGACGACCTGAGG	PRKG2	ENSG00000138669	-0.7750336349997258	[105]	[186]	-5	hSpCas9	negative selection	12418960