Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:5613
• Symbol:PRKX
• Description:protein kinase X-linked

DataSource: http://genomecrispr.dkfz.de/#!/results/PRKX

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
3713196	3713219	X	-	26472758	Jiyoye	viability	GGAGAGCGACTCCCGCAAGGTGG	PRKX	ENSG00000183943	0.16901564431110896	[91]	[77]	1	hSpCas9	negative selection	127566
3713184	3713207	X	+	26472758	Jiyoye	viability	GGGTCTCCTCCGCCACCTTGCGG	PRKX	ENSG00000183943	-0.14651565755900076	[501]	[341]	-1	hSpCas9	negative selection	127567
3615860	3615883	X	-	26472758	Jiyoye	viability	ATGATGTGAAGCATCATCGGTGG	PRKX	ENSG00000183943	0.40717538150587274	[0]	[0]	3	hSpCas9	negative selection	127568
3713074	3713097	X	+	26472758	Jiyoye	viability	CCGCACTCACTCACCCACGGTGG	PRKX	ENSG00000183943	0.49737319047745154	[92]	[98]	4	hSpCas9	negative selection	127569
3621258	3621281	X	-	26472758	Jiyoye	viability	AAGGCGATTAGGAAACATGAAGG	PRKX	ENSG00000183943	-1.268202414437501	[213]	[66]	-7	hSpCas9	negative selection	127570
3713139	3713162	X	+	26472758	Jiyoye	viability	GCGACAGCGCCTCAGGGCTGGGG	PRKX	ENSG00000183943	0.9546631768083664	[129]	[189]	6	hSpCas9	negative selection	127571
3655180	3655203	X	-	26472758	Jiyoye	viability	GGATGGCCACATTAAGCTCACGG	PRKX	ENSG00000183943	-0.3163069832967107	[70]	[42]	-2	hSpCas9	negative selection	127572
3713108	3713131	X	+	26472758	Jiyoye	viability	AAGTCCTGCAGGCTGTACACAGG	PRKX	ENSG00000183943	0.2788512845303341	[93]	[85]	2	hSpCas9	negative selection	127573
3713097	3713120	X	+	26472758	Jiyoye	viability	CCAGCGTGTCAAAGTCCTGCAGG	PRKX	ENSG00000183943	0.2986509247277044	[68]	[63]	2	hSpCas9	negative selection	127574
3655357	3655380	X	-	26472758	Jiyoye	viability	CATGCTCATGGAGTACGTGCCGG	PRKX	ENSG00000183943	-1.1271610461453148	[167]	[57]	-6	hSpCas9	negative selection	127575
3713196	3713219	X	-	26472758	KBM7	viability	GGAGAGCGACTCCCGCAAGGTGG	PRKX	ENSG00000183943	-0.6698608497426203	[351,182]	[78,74]	-5	hSpCas9	negative selection	318684
3713184	3713207	X	+	26472758	KBM7	viability	GGGTCTCCTCCGCCACCTTGCGG	PRKX	ENSG00000183943	0.3796449909976505	[1534,1226]	[805,868]	4	hSpCas9	negative selection	318685
3615860	3615883	X	-	26472758	KBM7	viability	ATGATGTGAAGCATCATCGGTGG	PRKX	ENSG00000183943	1.0816969781589814	[0,0]	[0,0]	9	hSpCas9	negative selection	318686
3713074	3713097	X	+	26472758	KBM7	viability	CCGCACTCACTCACCCACGGTGG	PRKX	ENSG00000183943	-0.46652483904444175	[383,259]	[108,106]	-4	hSpCas9	negative selection	318687
3621258	3621281	X	-	26472758	KBM7	viability	AAGGCGATTAGGAAACATGAAGG	PRKX	ENSG00000183943	0.5110850387436021	[487,522]	[462,232]	5	hSpCas9	negative selection	318688
3713139	3713162	X	+	26472758	KBM7	viability	GCGACAGCGCCTCAGGGCTGGGG	PRKX	ENSG00000183943	0.3597743136414896	[810,548]	[409,398]	4	hSpCas9	negative selection	318689
3655180	3655203	X	-	26472758	KBM7	viability	GGATGGCCACATTAAGCTCACGG	PRKX	ENSG00000183943	1.3470710687465843	[178,198]	[220,234]	9	hSpCas9	negative selection	318690
3713108	3713131	X	+	26472758	KBM7	viability	AAGTCCTGCAGGCTGTACACAGG	PRKX	ENSG00000183943	0.6797877035416775	[546,431]	[298,425]	7	hSpCas9	negative selection	318691
3713097	3713120	X	+	26472758	KBM7	viability	CCAGCGTGTCAAAGTCCTGCAGG	PRKX	ENSG00000183943	-0.10215432846736902	[418,401]	[164,193]	-1	hSpCas9	negative selection	318692
3655357	3655380	X	-	26472758	KBM7	viability	CATGCTCATGGAGTACGTGCCGG	PRKX	ENSG00000183943	0.9353238364105674	[468,669]	[706,359]	8	hSpCas9	negative selection	318693
3713196	3713219	X	-	26472758	Raji	viability	GGAGAGCGACTCCCGCAAGGTGG	PRKX	ENSG00000183943	0.5466685808991205	[176]	[59]	5	hSpCas9	negative selection	509802
3713184	3713207	X	+	26472758	Raji	viability	GGGTCTCCTCCGCCACCTTGCGG	PRKX	ENSG00000183943	0.16657932788149954	[763]	[198]	1	hSpCas9	negative selection	509803
3615860	3615883	X	-	26472758	Raji	viability	ATGATGTGAAGCATCATCGGTGG	PRKX	ENSG00000183943	2.1073835353735992	[0]	[0]	9	hSpCas9	negative selection	509804
3713074	3713097	X	+	26472758	Raji	viability	CCGCACTCACTCACCCACGGTGG	PRKX	ENSG00000183943	1.8551965117767981	[105]	[88]	9	hSpCas9	negative selection	509805
3621258	3621281	X	-	26472758	Raji	viability	AAGGCGATTAGGAAACATGAAGG	PRKX	ENSG00000183943	1.1253054433708618	[159]	[80]	8	hSpCas9	negative selection	509806
3713139	3713162	X	+	26472758	Raji	viability	GCGACAGCGCCTCAGGGCTGGGG	PRKX	ENSG00000183943	-0.34781109037722713	[339]	[61]	-3	hSpCas9	negative selection	509807
3655180	3655203	X	-	26472758	Raji	viability	GGATGGCCACATTAAGCTCACGG	PRKX	ENSG00000183943	0.8791145477004823	[163]	[69]	7	hSpCas9	negative selection	509808
3713108	3713131	X	+	26472758	Raji	viability	AAGTCCTGCAGGCTGTACACAGG	PRKX	ENSG00000183943	1.1164286749766066	[158]	[79]	8	hSpCas9	negative selection	509809
3713097	3713120	X	+	26472758	Raji	viability	CCAGCGTGTCAAAGTCCTGCAGG	PRKX	ENSG00000183943	-0.26899234353613943	[134]	[25]	-2	hSpCas9	negative selection	509810
3655357	3655380	X	-	26472758	Raji	viability	CATGCTCATGGAGTACGTGCCGG	PRKX	ENSG00000183943	1.3354581028535932	[180]	[105]	9	hSpCas9	negative selection	509811
3713196	3713219	X	-	26472758	K562	viability	GGAGAGCGACTCCCGCAAGGTGG	PRKX	ENSG00000183943	0.8544722093504337	[208]	[318]	7	hSpCas9	negative selection	700920
3713184	3713207	X	+	26472758	K562	viability	GGGTCTCCTCCGCCACCTTGCGG	PRKX	ENSG00000183943	0.6487169418486958	[1044]	[1382]	5	hSpCas9	negative selection	700921
3615860	3615883	X	-	26472758	K562	viability	ATGATGTGAAGCATCATCGGTGG	PRKX	ENSG00000183943	0.24441872766644757	[0]	[0]	2	hSpCas9	negative selection	700922
3713074	3713097	X	+	26472758	K562	viability	CCGCACTCACTCACCCACGGTGG	PRKX	ENSG00000183943	0.658257477361665	[300]	[400]	5	hSpCas9	negative selection	700923
3621258	3621281	X	-	26472758	K562	viability	AAGGCGATTAGGAAACATGAAGG	PRKX	ENSG00000183943	1.3284829924549213	[274]	[582]	9	hSpCas9	negative selection	700924
3713139	3713162	X	+	26472758	K562	viability	GCGACAGCGCCTCAGGGCTGGGG	PRKX	ENSG00000183943	-0.4837499182626003	[544]	[328]	-3	hSpCas9	negative selection	700925
3655180	3655203	X	-	26472758	K562	viability	GGATGGCCACATTAAGCTCACGG	PRKX	ENSG00000183943	0.6594562269452907	[236]	[315]	5	hSpCas9	negative selection	700926
3713108	3713131	X	+	26472758	K562	viability	AAGTCCTGCAGGCTGTACACAGG	PRKX	ENSG00000183943	1.0603356632274752	[383]	[675]	8	hSpCas9	negative selection	700927
3713097	3713120	X	+	26472758	K562	viability	CCAGCGTGTCAAAGTCCTGCAGG	PRKX	ENSG00000183943	0.34733704061201337	[283]	[304]	2	hSpCas9	negative selection	700928
3655357	3655380	X	-	26472758	K562	viability	CATGCTCATGGAGTACGTGCCGG	PRKX	ENSG00000183943	1.1251197992941027	[314]	[579]	8	hSpCas9	negative selection	700929
3713196	3713219	X	-	26627737	DLD1	viability	GGAGAGCGACTCCCGCAAGGTGG	PRKX	ENSG00000183943	0.919662584797038	[386]	[411,77,194]	8	hSpCas9	negative selection	845545
3713196	3713219	X	-	26627737	GBM cells	viability after 5 days	GGAGAGCGACTCCCGCAAGGTGG	PRKX	ENSG00000183943	0.15159491829990585	[302]	[181,178]	2	hSpCas9	negative selection	927860
3713196	3713219	X	-	26627737	GBM cells	viability after 13 days	GGAGAGCGACTCCCGCAAGGTGG	PRKX	ENSG00000183943	-0.5723045549014856	[302]	[141,84]	-6	hSpCas9	negative selection	1010175
3713196	3713219	X	-	26627737	GBM cells	viability after 21 days	GGAGAGCGACTCCCGCAAGGTGG	PRKX	ENSG00000183943	0.031950682585294266	[302]	[172,163]	0	hSpCas9	negative selection	1092490
3713196	3713219	X	-	26627737	RPE1	viability after 9 days	GGAGAGCGACTCCCGCAAGGTGG	PRKX	ENSG00000183943	1.3631145810042975	[792]	[580,712]	7	hSpCas9	negative selection	1174805
3713196	3713219	X	-	26627737	RPE1	viability after 12 days	GGAGAGCGACTCCCGCAAGGTGG	PRKX	ENSG00000183943	1.053955572724126	[792]	[419,465]	6	hSpCas9	negative selection	1257120
3713196	3713219	X	-	26627737	RPE1	viability after 15 days	GGAGAGCGACTCCCGCAAGGTGG	PRKX	ENSG00000183943	1.3632368959332133	[792]	[627,527]	7	hSpCas9	negative selection	1339435
3713196	3713219	X	-	26627737	RPE1	viability after 18 days	GGAGAGCGACTCCCGCAAGGTGG	PRKX	ENSG00000183943	1.3096292561148777	[792]	[485,577]	7	hSpCas9	negative selection	1421750
3713196	3713219	X	-	26627737	HeLa	viability after 8 days	GGAGAGCGACTCCCGCAAGGTGG	PRKX	ENSG00000183943	1.0621548135705312	[441]	[463,537,228]	7	hSpCas9	negative selection	1504065
3713196	3713219	X	-	26627737	HeLa	viability after 12 days	GGAGAGCGACTCCCGCAAGGTGG	PRKX	ENSG00000183943	0.17003048872941998	[441]	[187,167,263]	1	hSpCas9	negative selection	1586380
3713196	3713219	X	-	26627737	HeLa	viability after 15 days	GGAGAGCGACTCCCGCAAGGTGG	PRKX	ENSG00000183943	0.4824369045499719	[441]	[269,255,225]	4	hSpCas9	negative selection	1668695
3713196	3713219	X	-	26627737	HeLa	viability after 18 days	GGAGAGCGACTCCCGCAAGGTGG	PRKX	ENSG00000183943	0.45701602485797554	[441]	[182,198,225]	4	hSpCas9	negative selection	1751010
3713196	3713219	X	-	26627737	HCT116	viability after 6 days	GGAGAGCGACTCCCGCAAGGTGG	PRKX	ENSG00000183943	-0.4591848487321225	[568]	[66,63]	-3	hSpCas9	negative selection	1833325
3713196	3713219	X	-	26627737	HCT116	viability after 8 days	GGAGAGCGACTCCCGCAAGGTGG	PRKX	ENSG00000183943	0.5565342686711203	[309]	[229,246,275]	5	hSpCas9	negative selection	1915640
3713196	3713219	X	-	26627737	HCT116	viability after 9 days	GGAGAGCGACTCCCGCAAGGTGG	PRKX	ENSG00000183943	0.24195627018828136	[568]	[239,131]	1	hSpCas9	negative selection	1997955
3713196	3713219	X	-	26627737	HCT116	viability after 12 days	GGAGAGCGACTCCCGCAAGGTGG	PRKX	ENSG00000183943	0.7887519684894289	[309]	[258,309,277]	7	hSpCas9	negative selection	2080270
3713196	3713219	X	-	26627737	HCT116	viability after 15 days	GGAGAGCGACTCCCGCAAGGTGG	PRKX	ENSG00000183943	0.9401019000869066	[309]	[341,357,324]	7	hSpCas9	negative selection	2162585
3713196	3713219	X	-	26627737	HCT116	viability after 18 days	GGAGAGCGACTCCCGCAAGGTGG	PRKX	ENSG00000183943	0.38217047938954485	[309]	[128,307,138]	3	hSpCas9	negative selection	2244900
3713087	3713110	X	-	24336569	HL60	viability	TTTGACACGCTGGCCACCGTGGG	PRKX	ENSG00000183943	0.32630242820788224	[919]	[2440]	3	hSpCas9	negative selection	2286562
3713097	3713120	X	-	24336569	HL60	viability	CCTGCAGGACTTTGACACGCTGG	PRKX	ENSG00000183943	0.38660274283641294	[847]	[2345]	3	hSpCas9	negative selection	2286563
3713108	3713131	X	+	24336569	HL60	viability	AAGTCCTGCAGGCTGTACACAGG	PRKX	ENSG00000183943	0.05016949849160224	[805]	[1765]	0	hSpCas9	negative selection	2286564
3713117	3713140	X	+	24336569	HL60	viability	AGGCTGTACACAGGCGGCTCCGG	PRKX	ENSG00000183943	0.21573690835608947	[458]	[1127]	2	hSpCas9	negative selection	2286565
3713132	3713155	X	+	24336569	HL60	viability	GGCTCCGGCGACAGCGCCTCAGG	PRKX	ENSG00000183943	-0.8742829295286199	[394]	[455]	-7	hSpCas9	negative selection	2286566
3713137	3713160	X	+	24336569	HL60	viability	CGGCGACAGCGCCTCAGGGCTGG	PRKX	ENSG00000183943	-0.19842024697474558	[731]	[1349]	-2	hSpCas9	negative selection	2286567
3713184	3713207	X	+	24336569	HL60	viability	GGGTCTCCTCCGCCACCTTGCGG	PRKX	ENSG00000183943	0.3190206430212625	[410]	[1084]	3	hSpCas9	negative selection	2286568
3713190	3713213	X	-	24336569	HL60	viability	CGACTCCCGCAAGGTGGCGGAGG	PRKX	ENSG00000183943	1.9108179862102668	[163]	[1304]	9	hSpCas9	negative selection	2286569
3713196	3713219	X	-	24336569	HL60	viability	GGAGAGCGACTCCCGCAAGGTGG	PRKX	ENSG00000183943	1.1896596235869747	[288]	[1394]	8	hSpCas9	negative selection	2286570
3713203	3713226	X	+	24336569	HL60	viability	GCGGGAGTCGCTCTCCGCCGCGG	PRKX	ENSG00000183943	0.00044709715772117686	[290]	[615]	0	hSpCas9	negative selection	2286571
3713087	3713110	X	-	24336569	KBM7	viability	TTTGACACGCTGGCCACCGTGGG	PRKX	ENSG00000183943	0.024745874121527622	[718]	[1994]	0	hSpCas9	negative selection	2353739
3713097	3713120	X	-	24336569	KBM7	viability	CCTGCAGGACTTTGACACGCTGG	PRKX	ENSG00000183943	1.0503015593707332	[275]	[1558]	8	hSpCas9	negative selection	2353740
3713108	3713131	X	+	24336569	KBM7	viability	AAGTCCTGCAGGCTGTACACAGG	PRKX	ENSG00000183943	0.08180942373169087	[837]	[2418]	0	hSpCas9	negative selection	2353741
3713117	3713140	X	+	24336569	KBM7	viability	AGGCTGTACACAGGCGGCTCCGG	PRKX	ENSG00000183943	-0.0997531130511764	[529]	[1348]	-1	hSpCas9	negative selection	2353742
3713132	3713155	X	+	24336569	KBM7	viability	GGCTCCGGCGACAGCGCCTCAGG	PRKX	ENSG00000183943	0.9138117286705607	[237]	[1222]	7	hSpCas9	negative selection	2353743
3713137	3713160	X	+	24336569	KBM7	viability	CGGCGACAGCGCCTCAGGGCTGG	PRKX	ENSG00000183943	0.30994611888338974	[424]	[1436]	3	hSpCas9	negative selection	2353744
3713184	3713207	X	+	24336569	KBM7	viability	GGGTCTCCTCCGCCACCTTGCGG	PRKX	ENSG00000183943	-0.024321190465070197	[524]	[1407]	0	hSpCas9	negative selection	2353745
3713190	3713213	X	-	24336569	KBM7	viability	CGACTCCCGCAAGGTGGCGGAGG	PRKX	ENSG00000183943	1.088122084132948	[282]	[1640]	8	hSpCas9	negative selection	2353746
3713196	3713219	X	-	24336569	KBM7	viability	GGAGAGCGACTCCCGCAAGGTGG	PRKX	ENSG00000183943	-0.06277389868945393	[650]	[1699]	0	hSpCas9	negative selection	2353747
3713203	3713226	X	+	24336569	KBM7	viability	GCGGGAGTCGCTCTCCGCCGCGG	PRKX	ENSG00000183943	0.13640154500482665	[489]	[1468]	1	hSpCas9	negative selection	2353748
3648603	3648626	X	-	25494202	A375	resistance to PLX-4720 (puromycin)	ACACACACACACACACACAGGAG	PRKX	ENSG00000183943	0.19128589643959537	[429,108]	[111,17]	0	dCas9-VP64	positive selection	2424228
3701149	3701172	X	-	25494202	A375	resistance to PLX-4720 (puromycin)	GCGCCACTGCACTCCAGCCTTAG	PRKX	ENSG00000183943	0.12883397399525423	[86,65]	[25,8]	0	dCas9-VP64	positive selection	2424595
3627499	3627522	X	+	25494202	A375	resistance to PLX-4720 (puromycin)	TCTCCCAGGCTGGAGTGCAGCGG	PRKX	ENSG00000183943	-0.49998316673352905	[290,357]	[69,28]	-2	dCas9-VP64	positive selection	2425322
3623510	3623533	X	+	25494202	A375	resistance to PLX-4720 (puromycin)	TGTGCCACTGCACTCCAGCCGGG	PRKX	ENSG00000183943	-0.41902599900673143	[34,218]	[4,37]	-2	dCas9-VP64	positive selection	2439553
3634218	3634241	X	+	25494202	A375	resistance to PLX-4720 (puromycin)	CCAGCCTGGGTGACAGAGCAGGG	PRKX	ENSG00000183943	-0.21879118015331467	[3,55]	[3,6]	-1	dCas9-VP64	positive selection	2450599
3639122	3639145	X	+	25494202	A375	resistance to PLX-4720 (puromycin)	TGGATGGATGGATGGATGGAAGG	PRKX	ENSG00000183943	2.7644531499590617	[51,2]	[77,0]	8	dCas9-VP64	positive selection	2471353
3648603	3648626	X	-	25494202	A375	resistance to PLX-4720 (zeocin)	ACACACACACACACACACAGGAG	PRKX	ENSG00000183943	-0.29192793722986554	[278,490]	[95,106]	-3	dCas9-VP64	positive selection	2519483
3701149	3701172	X	-	25494202	A375	resistance to PLX-4720 (zeocin)	GCGCCACTGCACTCCAGCCTTAG	PRKX	ENSG00000183943	-0.30672599620467045	[261,149]	[50,57]	-3	dCas9-VP64	positive selection	2519850
3627499	3627522	X	+	25494202	A375	resistance to PLX-4720 (zeocin)	TCTCCCAGGCTGGAGTGCAGCGG	PRKX	ENSG00000183943	0.5593039216911941	[271,243]	[52,190]	4	dCas9-VP64	positive selection	2520577
3623510	3623533	X	+	25494202	A375	resistance to PLX-4720 (zeocin)	TGTGCCACTGCACTCCAGCCGGG	PRKX	ENSG00000183943	0.0771162345407751	[282,156]	[110,43]	0	dCas9-VP64	positive selection	2534808
3634218	3634241	X	+	25494202	A375	resistance to PLX-4720 (zeocin)	CCAGCCTGGGTGACAGAGCAGGG	PRKX	ENSG00000183943	1.4992476200347653	[28,23]	[15,31]	8	dCas9-VP64	positive selection	2545854
3639122	3639145	X	+	25494202	A375	resistance to PLX-4720 (zeocin)	TGGATGGATGGATGGATGGAAGG	PRKX	ENSG00000183943	-0.745179068402318	[185,151]	[42,22]	-7	dCas9-VP64	positive selection	2566608
3674597	3674620	X	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	ACAGCCTGATGAGGAACGGGTGG	PRKX	ENSG00000183943	-0.252825613026023	[3,3]	[2,2]	-4	hSpCas9	positive selection	3013722
3713204	3713227	X	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCGGGAGTCGCTCTCCGCCGCGG	PRKX	ENSG00000183943	-0.33687673889973313	[1,1]	[0,1]	-5	hSpCas9	positive selection	3013723
3655301	3655324	X	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GGCGCTTCTCCAGCACCACGGGG	PRKX	ENSG00000183943	-0.3121911653964864	[1,0]	[0,0]	-4	hSpCas9	positive selection	3013724
3655287	3655310	X	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TGCAGAGTAGAAGAGCCCCGTGG	PRKX	ENSG00000183943	0.47943545973673535	[3,2]	[5,2]	8	hSpCas9	positive selection	3013725
3674597	3674620	X	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	ACAGCCTGATGAGGAACGGGTGG	PRKX	ENSG00000183943	-0.28363680312593387	[3,3]	[3,0]	-4	hSpCas9	positive selection	3081580
3713204	3713227	X	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCGGGAGTCGCTCTCCGCCGCGG	PRKX	ENSG00000183943	-0.7117605672114179	[1,1]	[0,0]	-8	hSpCas9	positive selection	3081581
3655301	3655324	X	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GGCGCTTCTCCAGCACCACGGGG	PRKX	ENSG00000183943	0.34841334501875143	[1,1]	[2,0]	6	hSpCas9	positive selection	3081582
3655287	3655310	X	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TGCAGAGTAGAAGAGCCCCGTGG	PRKX	ENSG00000183943	-0.31952532015639457	[3,3]	[3,0]	-5	hSpCas9	positive selection	3081583
3655174	3655197		+	24336571	A375	resistance to PLX after 7 days	CAAAGTCCGTGAGCTTAATGTGG	PRKX	ENSG00000183943	0.25179092600155606	[8,8]	[10,9]	7	hSpCas9	positive selection	3137854
3674662	3674685		-	24336571	A375	resistance to PLX after 7 days	CGACGTCATCCGCCTAAAGCAGG	PRKX	ENSG00000183943	-0.4647089616655963	[8,5]	[4,5]	-9	hSpCas9	positive selection	3137855
3674650	3674673		+	24336571	A375	resistance to PLX after 7 days	GTACGTGTTGCTCCTGCTTTAGG	PRKX	ENSG00000183943	-0.015954341783887993	[21,17]	[17,20]	0	hSpCas9	positive selection	3137856
3655232	3655255		+	24336571	A375	resistance to PLX after 7 days	GTCCCTGTAGACGATCTCTTTGG	PRKX	ENSG00000183943	0.201666196585068	[16,20]	[20,21]	6	hSpCas9	positive selection	3137857
3655174	3655197		+	24336571	A375	resistance to PLX after 14 days	CAAAGTCCGTGAGCTTAATGTGG	PRKX	ENSG00000183943	0.5550492480238941	[8,6]	[4,4]	5	hSpCas9	positive selection	3195647
3674662	3674685		-	24336571	A375	resistance to PLX after 14 days	CGACGTCATCCGCCTAAAGCAGG	PRKX	ENSG00000183943	0.15272602291153126	[6,3]	[2,1]	1	hSpCas9	positive selection	3195648
3674650	3674673		+	24336571	A375	resistance to PLX after 14 days	GTACGTGTTGCTCCTGCTTTAGG	PRKX	ENSG00000183943	-0.18484676174384124	[23,13]	[9,4]	-2	hSpCas9	positive selection	3195649
3655232	3655255		+	24336571	A375	resistance to PLX after 14 days	GTCCCTGTAGACGATCTCTTTGG	PRKX	ENSG00000183943	-0.22890582023919426	[13,27]	[9,5]	-2	hSpCas9	positive selection	3195650
3655174	3655197		+	24336571	A375	viability after 7 days	CAAAGTCCGTGAGCTTAATGTGG	PRKX	ENSG00000183943	0.0038729905266015052	[8]	[8,8]	0	hSpCas9	negative selection	3253440
3674662	3674685		-	24336571	A375	viability after 7 days	CGACGTCATCCGCCTAAAGCAGG	PRKX	ENSG00000183943	-0.18531084305586792	[8]	[8,5]	-3	hSpCas9	negative selection	3253441
3674650	3674673		+	24336571	A375	viability after 7 days	GTACGTGTTGCTCCTGCTTTAGG	PRKX	ENSG00000183943	0.597858030044426	[13]	[21,17]	8	hSpCas9	negative selection	3253442
3655232	3655255		+	24336571	A375	viability after 7 days	GTCCCTGTAGACGATCTCTTTGG	PRKX	ENSG00000183943	0.4818806457590565	[13]	[16,20]	7	hSpCas9	negative selection	3253443
3655174	3655197		+	24336571	A375	viability after 14 days	CAAAGTCCGTGAGCTTAATGTGG	PRKX	ENSG00000183943	-0.14859720114653452	[8]	[8,6]	-2	hSpCas9	negative selection	3311233
3674662	3674685		-	24336571	A375	viability after 14 days	CGACGTCATCCGCCTAAAGCAGG	PRKX	ENSG00000183943	-0.6667011075067133	[8]	[6,3]	-7	hSpCas9	negative selection	3311234
3674650	3674673		+	24336571	A375	viability after 14 days	GTACGTGTTGCTCCTGCTTTAGG	PRKX	ENSG00000183943	0.5838068332810987	[13]	[23,13]	7	hSpCas9	negative selection	3311235
3655232	3655255		+	24336571	A375	viability after 14 days	GTCCCTGTAGACGATCTCTTTGG	PRKX	ENSG00000183943	0.6341722708452588	[13]	[13,27]	7	hSpCas9	negative selection	3311236
3655180	3655203	X	-	27383988	293T	resistance to West Nile virus (flavivirus)	GGATGGCCACATTAAGCTCACGG	PRKX	ENSG00000183943	3.556886493304743	[12,12]	[0,0]	9	hSpCas9	positive selection	3387531
3626432	3626455	X	-	27383988	293T	resistance to West Nile virus (flavivirus)	AATAGATTTCCCCAGACATTTGG	PRKX	ENSG00000183943	-0.8407058715146917	[273,273]	[0,0]	-6	hSpCas9	positive selection	3387532
3626421	3626444	X	+	27383988	293T	resistance to West Nile virus (flavivirus)	TACATGGAAATCCAAATGTCTGG	PRKX	ENSG00000183943	-1.5108581133310912	[435,435]	[0,0]	-8	hSpCas9	positive selection	3387533
3674596	3674619	X	+	26780180	HT29	viability (Avana library 4 designs)	ACAGCCTGATGAGGAACGGGTGG	PRKX	ENSG00000183943	0.498651103663056	[]	[]	1	hSpCas9	negative selection	3451915
3713203	3713226	X	+	26780180	HT29	viability (Avana library 4 designs)	GCGGGAGTCGCTCTCCGCCGCGG	PRKX	ENSG00000183943	0.373195967704352	[]	[]	1	hSpCas9	negative selection	3451916
3655301	3655324	X	-	26780180	HT29	viability (Avana library 4 designs)	GGCGCTTCTCCAGCACCACGGGG	PRKX	ENSG00000183943	0.545589297505764	[]	[]	2	hSpCas9	negative selection	3451917
3655286	3655309	X	+	26780180	HT29	viability (Avana library 4 designs)	TGCAGAGTAGAAGAGCCCCGTGG	PRKX	ENSG00000183943	2.21738408305565	[]	[]	7	hSpCas9	negative selection	3451918
3655286	3655309	X	+	26780180	A375	viability (Avana lentiCRISPRv2)	TGCAGAGTAGAAGAGCCCCGTGG	PRKX	ENSG00000183943	-5.08866618597551	[]	[]	-5	hSpCas9	negative selection	3548035
3713203	3713226	X	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCGGGAGTCGCTCTCCGCCGCGG	PRKX	ENSG00000183943	-6.82852586554378	[]	[]	-6	hSpCas9	negative selection	3548036
3655301	3655324	X	-	26780180	A375	viability (Avana lentiCRISPRv2)	GGCGCTTCTCCAGCACCACGGGG	PRKX	ENSG00000183943	2.02197580319165	[]	[]	3	hSpCas9	negative selection	3548037
3674596	3674619	X	+	26780180	A375	viability (Avana lentiCRISPRv2)	ACAGCCTGATGAGGAACGGGTGG	PRKX	ENSG00000183943	2.27851702597753	[]	[]	3	hSpCas9	negative selection	3548038
3713133	3713156	X	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCTCCGGCGACAGCGCCTCAGGG	PRKX	ENSG00000183943	5.77486566147119	[]	[]	9	hSpCas9	negative selection	3548039
3713193	3713216	X	-	26780180	A375	viability (Avana lentiCRISPRv2)	GAGCGACTCCCGCAAGGTGGCGG	PRKX	ENSG00000183943	4.65547298759856	[]	[]	7	hSpCas9	negative selection	3548040
3655286	3655309	X	+	26780180	A375	viability (Avana lentiGuide)	TGCAGAGTAGAAGAGCCCCGTGG	PRKX	ENSG00000183943	5.53933240224247	[]	[]	5	hSpCas9	negative selection	3656694
3713203	3713226	X	+	26780180	A375	viability (Avana lentiGuide)	GCGGGAGTCGCTCTCCGCCGCGG	PRKX	ENSG00000183943	6.13841779998943	[]	[]	5	hSpCas9	negative selection	3656695
3655301	3655324	X	-	26780180	A375	viability (Avana lentiGuide)	GGCGCTTCTCCAGCACCACGGGG	PRKX	ENSG00000183943	4.65779039963229	[]	[]	4	hSpCas9	negative selection	3656696
3674596	3674619	X	+	26780180	A375	viability (Avana lentiGuide)	ACAGCCTGATGAGGAACGGGTGG	PRKX	ENSG00000183943	5.81222928490474	[]	[]	5	hSpCas9	negative selection	3656697
3713133	3713156	X	+	26780180	A375	viability (Avana lentiGuide)	GCTCCGGCGACAGCGCCTCAGGG	PRKX	ENSG00000183943	-1.06417377384987	[]	[]	-2	hSpCas9	negative selection	3656698
3713193	3713216	X	-	26780180	A375	viability (Avana lentiGuide)	GAGCGACTCCCGCAAGGTGGCGG	PRKX	ENSG00000183943	2.35210594343373	[]	[]	2	hSpCas9	negative selection	3656699
3655286	3655309	X	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TGCAGAGTAGAAGAGCCCCGTGG	PRKX	ENSG00000183943	-0.5171972325032181	[4]	[3,1]	-6	hSpCas9	positive selection	3765301
3713203	3713226	X	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCGGGAGTCGCTCTCCGCCGCGG	PRKX	ENSG00000183943	-1.5931008325725378	[2]	[0,0]	-9	hSpCas9	positive selection	3765302
3655301	3655324	X	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGCGCTTCTCCAGCACCACGGGG	PRKX	ENSG00000183943	0.11973898844517183	[3]	[3,2]	3	hSpCas9	positive selection	3765303
3674596	3674619	X	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ACAGCCTGATGAGGAACGGGTGG	PRKX	ENSG00000183943	-0.04555392967032146	[4]	[4,4]	-1	hSpCas9	positive selection	3765304
3713133	3713156	X	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCTCCGGCGACAGCGCCTCAGGG	PRKX	ENSG00000183943	0.4011708079914724	[5]	[7,6]	9	hSpCas9	positive selection	3765305
3713193	3713216	X	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GAGCGACTCCCGCAAGGTGGCGG	PRKX	ENSG00000183943	0.14791844539807142	[4]	[5,3]	4	hSpCas9	positive selection	3765306
3655286	3655309	X	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TGCAGAGTAGAAGAGCCCCGTGG	PRKX	ENSG00000183943	-0.22747469188974492	[5]	[2,4]	-3	hSpCas9	positive selection	3873908
3713203	3713226	X	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCGGGAGTCGCTCTCCGCCGCGG	PRKX	ENSG00000183943	-0.3407838509152002	[3]	[0,3]	-4	hSpCas9	positive selection	3873909
3655301	3655324	X	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGCGCTTCTCCAGCACCACGGGG	PRKX	ENSG00000183943	-0.5138399838325824	[2]	[1,1]	-6	hSpCas9	positive selection	3873910
3674596	3674619	X	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ACAGCCTGATGAGGAACGGGTGG	PRKX	ENSG00000183943	-0.06804065327430867	[5]	[3,4]	-1	hSpCas9	positive selection	3873911
3713133	3713156	X	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCTCCGGCGACAGCGCCTCAGGG	PRKX	ENSG00000183943	0.15643700544958888	[6]	[5,5]	3	hSpCas9	positive selection	3873912
3713193	3713216	X	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GAGCGACTCCCGCAAGGTGGCGG	PRKX	ENSG00000183943	0.21478093028202447	[5]	[4,5]	5	hSpCas9	positive selection	3873913
3626432	3626455	X	-	26780180	A375	viability	AATAGATTTCCCCAGACATTTGG	PRKX	ENSG00000183943	-0.164473205814177	[]	[]	-5	hSpCas9	negative selection	3984366
3674662	3674685	X	-	26780180	A375	viability	CGACGTCATCCGCCTAAAGCAGG	PRKX	ENSG00000183943	0.865934555216758	[]	[]	3	hSpCas9	negative selection	3984367
3655180	3655203	X	-	26780180	A375	viability	GGATGGCCACATTAAGCTCACGG	PRKX	ENSG00000183943	1.00352200814999	[]	[]	4	hSpCas9	negative selection	3984368
3674650	3674673	X	+	26780180	A375	viability	GTACGTGTTGCTCCTGCTTTAGG	PRKX	ENSG00000183943	0.345586441225684	[]	[]	0	hSpCas9	negative selection	3984369
3626421	3626444	X	+	26780180	A375	viability	TACATGGAAATCCAAATGTCTGG	PRKX	ENSG00000183943	1.22559622229111	[]	[]	6	hSpCas9	negative selection	3984370
3655338	3655361	X	+	26780180	A375	viability	TAGCTGAAGAGCTCGCCGCCCGG	PRKX	ENSG00000183943	1.92358158122099	[]	[]	9	hSpCas9	negative selection	3984371
3626432	3626455	X	-	26780180	HT29	viability (GeCKOv2 library)	AATAGATTTCCCCAGACATTTGG	PRKX	ENSG00000183943	0.328910061143679	[]	[]	0	hSpCas9	negative selection	4092332
3674662	3674685	X	-	26780180	HT29	viability (GeCKOv2 library)	CGACGTCATCCGCCTAAAGCAGG	PRKX	ENSG00000183943	0.442784374448377	[]	[]	1	hSpCas9	negative selection	4092333
3655180	3655203	X	-	26780180	HT29	viability (GeCKOv2 library)	GGATGGCCACATTAAGCTCACGG	PRKX	ENSG00000183943	1.50918531130842	[]	[]	7	hSpCas9	negative selection	4092334
3674650	3674673	X	+	26780180	HT29	viability (GeCKOv2 library)	GTACGTGTTGCTCCTGCTTTAGG	PRKX	ENSG00000183943	-0.832465794985329	[]	[]	-9	hSpCas9	negative selection	4092335
3626421	3626444	X	+	26780180	HT29	viability (GeCKOv2 library)	TACATGGAAATCCAAATGTCTGG	PRKX	ENSG00000183943	1.12246772364297	[]	[]	5	hSpCas9	negative selection	4092336
3655338	3655361	X	+	26780180	HT29	viability (GeCKOv2 library)	TAGCTGAAGAGCTCGCCGCCCGG	PRKX	ENSG00000183943	3.00352227720535	[]	[]	9	hSpCas9	negative selection	4092337
3655174	3655197	X	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CAAAGTCCGTGAGCTTAATGTGG	PRKX	ENSG00000183943	0.6970707918042645	[3]	[5,2]	9	hSpCas9	positive selection	4163019
3674662	3674685	X	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CGACGTCATCCGCCTAAAGCAGG	PRKX	ENSG00000183943	-0.6840008446929526	[2]	[0,1]	-9	hSpCas9	positive selection	4163020
3674650	3674673	X	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GTACGTGTTGCTCCTGCTTTAGG	PRKX	ENSG00000183943	0.006643263489874041	[4]	[2,2]	0	hSpCas9	positive selection	4163021
3655232	3655255	X	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GTCCCTGTAGACGATCTCTTTGG	PRKX	ENSG00000183943	-0.16602161233087825	[4]	[1,2]	-4	hSpCas9	positive selection	4163022
3655174	3655197	X	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CAAAGTCCGTGAGCTTAATGTGG	PRKX	ENSG00000183943	-0.029878043299991386	[3]	[1,1,1,0]	0	hSpCas9	positive selection	4227041
3674662	3674685	X	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CGACGTCATCCGCCTAAAGCAGG	PRKX	ENSG00000183943	0.5302312331070955	[2]	[0,2,3,0]	3	hSpCas9	positive selection	4227042
3674650	3674673	X	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GTACGTGTTGCTCCTGCTTTAGG	PRKX	ENSG00000183943	-0.35116895522229	[3]	[0,2,0,0]	-5	hSpCas9	positive selection	4227043
3655232	3655255	X	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GTCCCTGTAGACGATCTCTTTGG	PRKX	ENSG00000183943	1.3916730844079293	[3]	[4,4,1,4]	9	hSpCas9	positive selection	4227044
3674662	3674685	X	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CGACGTCATCCGCCTAAAGCAGG	PRKX	ENSG00000183943	0.23147118825469676	[4]	[4,3]	4	hSpCas9	positive selection	4292228
3655338	3655361	X	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TAGCTGAAGAGCTCGCCGCCCGG	PRKX	ENSG00000183943	-0.47772406031066217	[4]	[3,0]	-8	hSpCas9	positive selection	4292229
3674650	3674673	X	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GTACGTGTTGCTCCTGCTTTAGG	PRKX	ENSG00000183943	0.3924275701513379	[3]	[3,3]	7	hSpCas9	positive selection	4292230
3655180	3655203	X	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GGATGGCCACATTAAGCTCACGG	PRKX	ENSG00000183943	-0.055678037971500616	[1]	[1,0]	-1	hSpCas9	positive selection	4356486
3626432	3626455	X	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AATAGATTTCCCCAGACATTTGG	PRKX	ENSG00000183943	-0.07152311105680392	[3]	[3,1]	-1	hSpCas9	positive selection	4356487
3626421	3626444	X	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TACATGGAAATCCAAATGTCTGG	PRKX	ENSG00000183943	0.017856388560316128	[4]	[3,2]	0	hSpCas9	positive selection	4356488
3655322	3655344	X	-	27760321	OCIAML3	viability	CAGCTACCTGCGCAACCGGGGG	PRKX	ENSG00000183943	-0.041770273268993074	[680,525]	[383,547]	0	hSpCas9	negative selection	4430681
3655397	3655419	X	+	27760321	OCIAML3	viability	ATGCCACGTCCAGAACCTGCGG	PRKX	ENSG00000183943	0.8015741638215776	[1569,1280]	[1787,2122]	8	hSpCas9	negative selection	4430682
3674654	3674676	X	+	27760321	OCIAML3	viability	GTGTTGCTCCTGCTTTAGGCGG	PRKX	ENSG00000183943	0.5676901487929765	[687,669]	[691,914]	6	hSpCas9	negative selection	4430683
3674737	3674759	X	-	27760321	OCIAML3	viability	ACGTTCGGGCGGGTGCACCTGG	PRKX	ENSG00000183943	-0.6461091288524117	[526,423]	[178,310]	-6	hSpCas9	negative selection	4430684
3713112	3713134	X	+	27760321	OCIAML3	viability	CCTGCAGGCTGTACACAGGCGG	PRKX	ENSG00000183943	0.6274224798174781	[473,379]	[462,577]	7	hSpCas9	negative selection	4430685
3655322	3655344	X	-	27760321	OCIAML2	viability	CAGCTACCTGCGCAACCGGGGG	PRKX	ENSG00000183943	-0.40054209257232826	[680,525]	[279,481]	-5	hSpCas9	negative selection	4514144
3655397	3655419	X	+	27760321	OCIAML2	viability	ATGCCACGTCCAGAACCTGCGG	PRKX	ENSG00000183943	0.1525070175266927	[1569,1280]	[1106,1496]	2	hSpCas9	negative selection	4514145
3674654	3674676	X	+	27760321	OCIAML2	viability	GTGTTGCTCCTGCTTTAGGCGG	PRKX	ENSG00000183943	0.49914859869649153	[687,669]	[686,897]	6	hSpCas9	negative selection	4514146
3674737	3674759	X	-	27760321	OCIAML2	viability	ACGTTCGGGCGGGTGCACCTGG	PRKX	ENSG00000183943	-0.6127852354302368	[526,423]	[209,302]	-6	hSpCas9	negative selection	4514147
3713112	3713134	X	+	27760321	OCIAML2	viability	CCTGCAGGCTGTACACAGGCGG	PRKX	ENSG00000183943	0.07452329539025321	[473,379]	[308,430]	0	hSpCas9	negative selection	4514148
3655322	3655344	X	-	27760321	MV411	viability	CAGCTACCTGCGCAACCGGGGG	PRKX	ENSG00000183943	-0.4823563270041041	[680,525]	[284,279]	-3	hSpCas9	negative selection	4597607
3655397	3655419	X	+	27760321	MV411	viability	ATGCCACGTCCAGAACCTGCGG	PRKX	ENSG00000183943	1.6957110001876137	[1569,1280]	[3616,2152]	9	hSpCas9	negative selection	4597608
3674654	3674676	X	+	27760321	MV411	viability	GTGTTGCTCCTGCTTTAGGCGG	PRKX	ENSG00000183943	0.9066298840118655	[687,669]	[1117,426]	6	hSpCas9	negative selection	4597609
3674737	3674759	X	-	27760321	MV411	viability	ACGTTCGGGCGGGTGCACCTGG	PRKX	ENSG00000183943	0.2599235477886571	[526,423]	[399,333]	1	hSpCas9	negative selection	4597610
3713112	3713134	X	+	27760321	MV411	viability	CCTGCAGGCTGTACACAGGCGG	PRKX	ENSG00000183943	1.8913917945335925	[473,379]	[1235,743]	9	hSpCas9	negative selection	4597611
3655322	3655344	X	-	27760321	HL60	viability	CAGCTACCTGCGCAACCGGGGG	PRKX	ENSG00000183943	-0.6375643759282166	[680,525]	[300,328]	-6	hSpCas9	negative selection	4681070
3655397	3655419	X	+	27760321	HL60	viability	ATGCCACGTCCAGAACCTGCGG	PRKX	ENSG00000183943	0.8721481485478493	[1569,1280]	[2142,2096]	8	hSpCas9	negative selection	4681071
3674654	3674676	X	+	27760321	HL60	viability	GTGTTGCTCCTGCTTTAGGCGG	PRKX	ENSG00000183943	0.5259714586378358	[687,669]	[813,785]	6	hSpCas9	negative selection	4681072
3674737	3674759	X	-	27760321	HL60	viability	ACGTTCGGGCGGGTGCACCTGG	PRKX	ENSG00000183943	0.3260799734876862	[526,423]	[407,564]	4	hSpCas9	negative selection	4681073
3713112	3713134	X	+	27760321	HL60	viability	CCTGCAGGCTGTACACAGGCGG	PRKX	ENSG00000183943	0.8165818782053786	[473,379]	[603,617]	8	hSpCas9	negative selection	4681074
3655322	3655344	X	-	27760321	HT1080	viability	CAGCTACCTGCGCAACCGGGGG	PRKX	ENSG00000183943	-0.4615419233989341	[525,410]	[125,145]	-2	hSpCas9	negative selection	4764533
3655397	3655419	X	+	27760321	HT1080	viability	ATGCCACGTCCAGAACCTGCGG	PRKX	ENSG00000183943	1.252072468987222	[1280,999]	[948,1227]	6	hSpCas9	negative selection	4764534
3674654	3674676	X	+	27760321	HT1080	viability	GTGTTGCTCCTGCTTTAGGCGG	PRKX	ENSG00000183943	0.9806853486285392	[669,522]	[414,527]	5	hSpCas9	negative selection	4764535
3674737	3674759	X	-	27760321	HT1080	viability	ACGTTCGGGCGGGTGCACCTGG	PRKX	ENSG00000183943	-2.4824995691046343	[423,330]	[24,28]	-7	hSpCas9	negative selection	4764536
3713112	3713134	X	+	27760321	HT1080	viability	CCTGCAGGCTGTACACAGGCGG	PRKX	ENSG00000183943	-1.3595936409914087	[379,296]	[0,108]	-5	hSpCas9	negative selection	4764537
3655322	3655344	X	-	27760321	HT29	viability after 7 days	CAGCTACCTGCGCAACCGGGGG	PRKX	ENSG00000183943	0.45895309339819795	[525,410]	[629,880,939]	7	hSpCas9	negative selection	4847996
3655397	3655419	X	+	27760321	HT29	viability after 7 days	ATGCCACGTCCAGAACCTGCGG	PRKX	ENSG00000183943	0.4012303928519194	[1280,999]	[2239,2210,1415]	6	hSpCas9	negative selection	4847997
3674654	3674676	X	+	27760321	HT29	viability after 7 days	GTGTTGCTCCTGCTTTAGGCGG	PRKX	ENSG00000183943	0.022486435145196326	[669,522]	[905,702,745]	0	hSpCas9	negative selection	4847998
3674737	3674759	X	-	27760321	HT29	viability after 7 days	ACGTTCGGGCGGGTGCACCTGG	PRKX	ENSG00000183943	0.12178334766100257	[423,330]	[646,503,451]	1	hSpCas9	negative selection	4847999
3713112	3713134	X	+	27760321	HT29	viability after 7 days	CCTGCAGGCTGTACACAGGCGG	PRKX	ENSG00000183943	0.2771539679529256	[379,296]	[607,360,620]	4	hSpCas9	negative selection	4848000
3655322	3655344	X	-	27760321	HT29	viability after 25 days	CAGCTACCTGCGCAACCGGGGG	PRKX	ENSG00000183943	0.0021862229076783923	[525,410]	[568,430,613]	0	hSpCas9	negative selection	4931459
3655397	3655419	X	+	27760321	HT29	viability after 25 days	ATGCCACGTCCAGAACCTGCGG	PRKX	ENSG00000183943	1.0234132051358569	[1280,999]	[2554,2205,3251]	9	hSpCas9	negative selection	4931460
3674654	3674676	X	+	27760321	HT29	viability after 25 days	GTGTTGCTCCTGCTTTAGGCGG	PRKX	ENSG00000183943	0.4306578410071109	[669,522]	[879,747,1153]	5	hSpCas9	negative selection	4931461
3674737	3674759	X	-	27760321	HT29	viability after 25 days	ACGTTCGGGCGGGTGCACCTGG	PRKX	ENSG00000183943	0.028573566224799646	[423,330]	[336,453,545]	0	hSpCas9	negative selection	4931462
3713112	3713134	X	+	27760321	HT29	viability after 25 days	CCTGCAGGCTGTACACAGGCGG	PRKX	ENSG00000183943	0.4581608870234388	[379,296]	[630,436,517]	5	hSpCas9	negative selection	4931463
3655322	3655344	X	-	27760321	HT29	viability after 22 days	CAGCTACCTGCGCAACCGGGGG	PRKX	ENSG00000183943	-0.042996099990865844	[525,410]	[460,587,529]	0	hSpCas9	negative selection	5014922
3655397	3655419	X	+	27760321	HT29	viability after 22 days	ATGCCACGTCCAGAACCTGCGG	PRKX	ENSG00000183943	0.9886714048862082	[1280,999]	[2571,2679,2597]	9	hSpCas9	negative selection	5014923
3674654	3674676	X	+	27760321	HT29	viability after 22 days	GTGTTGCTCCTGCTTTAGGCGG	PRKX	ENSG00000183943	0.4181261400773386	[669,522]	[783,952,1031]	4	hSpCas9	negative selection	5014924
3674737	3674759	X	-	27760321	HT29	viability after 22 days	ACGTTCGGGCGGGTGCACCTGG	PRKX	ENSG00000183943	0.16068127344672808	[423,330]	[488,532,440]	1	hSpCas9	negative selection	5014925
3713112	3713134	X	+	27760321	HT29	viability after 22 days	CCTGCAGGCTGTACACAGGCGG	PRKX	ENSG00000183943	0.7647086491753604	[379,296]	[783,493,713]	8	hSpCas9	negative selection	5014926
3655322	3655344	X	-	27760321	HT29	viability after 19 days	CAGCTACCTGCGCAACCGGGGG	PRKX	ENSG00000183943	0.14193714852777367	[525,410]	[380,635,728]	1	hSpCas9	negative selection	5098385
3655397	3655419	X	+	27760321	HT29	viability after 19 days	ATGCCACGTCCAGAACCTGCGG	PRKX	ENSG00000183943	1.0026217278891263	[1280,999]	[2814,2006,3021]	9	hSpCas9	negative selection	5098386
3674654	3674676	X	+	27760321	HT29	viability after 19 days	GTGTTGCTCCTGCTTTAGGCGG	PRKX	ENSG00000183943	0.7020050537736715	[669,522]	[1149,862,1311]	7	hSpCas9	negative selection	5098387
3674737	3674759	X	-	27760321	HT29	viability after 19 days	ACGTTCGGGCGGGTGCACCTGG	PRKX	ENSG00000183943	-0.1976415514952968	[423,330]	[687,183,292]	-2	hSpCas9	negative selection	5098388
3713112	3713134	X	+	27760321	HT29	viability after 19 days	CCTGCAGGCTGTACACAGGCGG	PRKX	ENSG00000183943	0.7322914672478035	[379,296]	[537,786,594]	7	hSpCas9	negative selection	5098389
3655322	3655344	X	-	27760321	HT29	viability after 16 days	CAGCTACCTGCGCAACCGGGGG	PRKX	ENSG00000183943	-0.178029591363998	[525,410]	[479,406,505]	-2	hSpCas9	negative selection	5181848
3655397	3655419	X	+	27760321	HT29	viability after 16 days	ATGCCACGTCCAGAACCTGCGG	PRKX	ENSG00000183943	0.862820966716991	[1280,999]	[2251,2082,2625]	8	hSpCas9	negative selection	5181849
3674654	3674676	X	+	27760321	HT29	viability after 16 days	GTGTTGCTCCTGCTTTAGGCGG	PRKX	ENSG00000183943	0.4560560552896489	[669,522]	[923,805,1019]	5	hSpCas9	negative selection	5181850
3674737	3674759	X	-	27760321	HT29	viability after 16 days	ACGTTCGGGCGGGTGCACCTGG	PRKX	ENSG00000183943	0.22715812229872823	[423,330]	[540,511,433]	2	hSpCas9	negative selection	5181851
3713112	3713134	X	+	27760321	HT29	viability after 16 days	CCTGCAGGCTGTACACAGGCGG	PRKX	ENSG00000183943	0.7581391867086061	[379,296]	[612,526,781]	8	hSpCas9	negative selection	5181852
3655322	3655344	X	-	27760321	HT29	viability after 13 days	CAGCTACCTGCGCAACCGGGGG	PRKX	ENSG00000183943	0.1580854472534728	[525,410]	[564,622,629]	2	hSpCas9	negative selection	5265311
3655397	3655419	X	+	27760321	HT29	viability after 13 days	ATGCCACGTCCAGAACCTGCGG	PRKX	ENSG00000183943	0.8200341796575858	[1280,999]	[2120,2537,2347]	9	hSpCas9	negative selection	5265312
3674654	3674676	X	+	27760321	HT29	viability after 13 days	GTGTTGCTCCTGCTTTAGGCGG	PRKX	ENSG00000183943	0.833460596342162	[669,522]	[983,1503,1212]	9	hSpCas9	negative selection	5265313
3674737	3674759	X	-	27760321	HT29	viability after 13 days	ACGTTCGGGCGGGTGCACCTGG	PRKX	ENSG00000183943	0.1428074250554864	[423,330]	[607,406,437]	1	hSpCas9	negative selection	5265314
3713112	3713134	X	+	27760321	HT29	viability after 13 days	CCTGCAGGCTGTACACAGGCGG	PRKX	ENSG00000183943	0.4768602672541478	[379,296]	[530,448,652]	6	hSpCas9	negative selection	5265315
3655322	3655344	X	-	27760321	HT29	viability after 10 days	CAGCTACCTGCGCAACCGGGGG	PRKX	ENSG00000183943	0.3767157738052455	[525,410]	[464,1181,645]	5	hSpCas9	negative selection	5348774
3655397	3655419	X	+	27760321	HT29	viability after 10 days	ATGCCACGTCCAGAACCTGCGG	PRKX	ENSG00000183943	0.562884695394009	[1280,999]	[2342,2009,1957]	7	hSpCas9	negative selection	5348775
3674654	3674676	X	+	27760321	HT29	viability after 10 days	GTGTTGCTCCTGCTTTAGGCGG	PRKX	ENSG00000183943	0.19662305294385118	[669,522]	[925,872,763]	2	hSpCas9	negative selection	5348776
3674737	3674759	X	-	27760321	HT29	viability after 10 days	ACGTTCGGGCGGGTGCACCTGG	PRKX	ENSG00000183943	-0.029217067470092735	[423,330]	[461,409,510]	0	hSpCas9	negative selection	5348777
3713112	3713134	X	+	27760321	HT29	viability after 10 days	CCTGCAGGCTGTACACAGGCGG	PRKX	ENSG00000183943	0.6591457148566487	[379,296]	[778,631,591]	8	hSpCas9	negative selection	5348778
3655322	3655344	X	-	27760321	MOLM13	viability	CAGCTACCTGCGCAACCGGGGG	PRKX	ENSG00000183943	-0.030340071039318073	[680,525]	[310,347]	0	hSpCas9	negative selection	5432237
3655397	3655419	X	+	27760321	MOLM13	viability	ATGCCACGTCCAGAACCTGCGG	PRKX	ENSG00000183943	1.5365785912331047	[1569,1280]	[2691,2005]	9	hSpCas9	negative selection	5432238
3674654	3674676	X	+	27760321	MOLM13	viability	GTGTTGCTCCTGCTTTAGGCGG	PRKX	ENSG00000183943	1.0013175110974442	[687,669]	[1103,482]	7	hSpCas9	negative selection	5432239
3674737	3674759	X	-	27760321	MOLM13	viability	ACGTTCGGGCGGGTGCACCTGG	PRKX	ENSG00000183943	-0.7340364650727288	[526,423]	[134,181]	-4	hSpCas9	negative selection	5432240
3713112	3713134	X	+	27760321	MOLM13	viability	CCTGCAGGCTGTACACAGGCGG	PRKX	ENSG00000183943	1.0430937877141238	[473,379]	[774,253]	7	hSpCas9	negative selection	5432241
3713133	3713156	X	+	27661255	K562	viability	GCTCCGGCGACAGCGCCTCAGGG	PRKX	ENSG00000183943	0.07793991269525724	[471,522]	[449,391]	2	dCas9-KRAB	negative selection	5504224
3713184	3713207	X	+	27661255	K562	viability	GGGTCTCCTCCGCCACCTTGCGG	PRKX	ENSG00000183943	0.011713797018251926	[1818,1728]	[1545,1330]	0	dCas9-KRAB	negative selection	5504225
3713411	3713434	X	+	27661255	K562	viability	GAGCGACGGGGACAATGGCTGGG	PRKX	ENSG00000183943	-0.02888009909211675	[368,448]	[337,302]	-1	dCas9-KRAB	negative selection	5504226
3713175	3713198	X	-	27661255	K562	viability	GGCGGAGGAGACCCCCGACGGGG	PRKX	ENSG00000183943	0.21609080059247593	[628,825]	[742,610]	7	dCas9-KRAB	negative selection	5504227
3713196	3713219	X	-	27661255	K562	viability	GGAGAGCGACTCCCGCAAGGTGG	PRKX	ENSG00000183943	0.13322437164863243	[431,379]	[396,321]	4	dCas9-KRAB	negative selection	5504228
3713199	3713222	X	-	27661255	K562	viability	GGCGGAGAGCGACTCCCGCAAGG	PRKX	ENSG00000183943	0.3342831497367046	[311,399]	[384,332]	9	dCas9-KRAB	negative selection	5504229
3713380	3713403	X	-	27661255	K562	viability	GCGCCGGACCGCGCACCAGGAGG	PRKX	ENSG00000183943	-0.2359266714385715	[292,261]	[220,160]	-6	dCas9-KRAB	negative selection	5504230
3674662	3674685	X	-	27260156	BXPC3	viability	CGACGTCATCCGCCTAAAGCAGG	PRKX	ENSG00000183943	0.10358906235668308	[1416]	[1422,1548,1637,1792]	2	hSpCas9	negative selection	5564688
3655338	3655361	X	+	27260156	BXPC3	viability	TAGCTGAAGAGCTCGCCGCCCGG	PRKX	ENSG00000183943	-0.23535546285539444	[1054]	[892,830,1023,1015]	-5	hSpCas9	negative selection	5564689
3674650	3674673	X	+	27260156	BXPC3	viability	GTACGTGTTGCTCCTGCTTTAGG	PRKX	ENSG00000183943	0.4461807115429356	[760]	[950,1097,1050,1263]	8	hSpCas9	negative selection	5564690
3655180	3655203	X	-	27260156	BXPC3	viability	GGATGGCCACATTAAGCTCACGG	PRKX	ENSG00000183943	-0.880443850035139	[134]	[49,43,101,120]	-9	hSpCas9	negative selection	5628946
3626432	3626455	X	-	27260156	BXPC3	viability	AATAGATTTCCCCAGACATTTGG	PRKX	ENSG00000183943	0.3028087163185128	[578]	[741,577,760,934]	6	hSpCas9	negative selection	5628947
3626421	3626444	X	+	27260156	BXPC3	viability	TACATGGAAATCCAAATGTCTGG	PRKX	ENSG00000183943	-0.15780968373713233	[1073]	[798,943,1111,1218]	-4	hSpCas9	negative selection	5628948
3674662	3674685	X	-	27260156	A673	viability	CGACGTCATCCGCCTAAAGCAGG	PRKX	ENSG00000183943	0.18671252137267302	[1416]	[1949,1947,1816,2034]	4	hSpCas9	negative selection	5685939
3655338	3655361	X	+	27260156	A673	viability	TAGCTGAAGAGCTCGCCGCCCGG	PRKX	ENSG00000183943	-0.2768869132908348	[1054]	[1206,807,954,1246]	-6	hSpCas9	negative selection	5685940
3674650	3674673	X	+	27260156	A673	viability	GTACGTGTTGCTCCTGCTTTAGG	PRKX	ENSG00000183943	0.38757845069796903	[760]	[1509,951,1179,1178]	8	hSpCas9	negative selection	5685941
3655180	3655203	X	-	27260156	A673	viability	GGATGGCCACATTAAGCTCACGG	PRKX	ENSG00000183943	-1.7493153756437965	[134]	[63,43,49,35]	-9	hSpCas9	negative selection	5750197
3626432	3626455	X	-	27260156	A673	viability	AATAGATTTCCCCAGACATTTGG	PRKX	ENSG00000183943	0.36785392691308794	[578]	[1021,870,908,793]	8	hSpCas9	negative selection	5750198
3626421	3626444	X	+	27260156	A673	viability	TACATGGAAATCCAAATGTCTGG	PRKX	ENSG00000183943	-0.17778741318399582	[1073]	[1272,1133,990,1178]	-4	hSpCas9	negative selection	5750199
3674662	3674685	X	-	27260156	A375	viability	CGACGTCATCCGCCTAAAGCAGG	PRKX	ENSG00000183943	0.3605238296116702	[1416]	[1881,2962,1478,2264]	5	hSpCas9	negative selection	5807190
3655338	3655361	X	+	27260156	A375	viability	TAGCTGAAGAGCTCGCCGCCCGG	PRKX	ENSG00000183943	-0.13796670987189152	[1054]	[1255,1055,913,1227]	-2	hSpCas9	negative selection	5807191
3674650	3674673	X	+	27260156	A375	viability	GTACGTGTTGCTCCTGCTTTAGG	PRKX	ENSG00000183943	0.5779138245904619	[760]	[1280,1569,1292,1205]	8	hSpCas9	negative selection	5807192
3655180	3655203	X	-	27260156	A375	viability	GGATGGCCACATTAAGCTCACGG	PRKX	ENSG00000183943	-0.40975039661608403	[134]	[135,193,110,51]	-5	hSpCas9	negative selection	5871448
3626432	3626455	X	-	27260156	A375	viability	AATAGATTTCCCCAGACATTTGG	PRKX	ENSG00000183943	0.5892606740108768	[578]	[937,1223,887,1040]	8	hSpCas9	negative selection	5871449
3626421	3626444	X	+	27260156	A375	viability	TACATGGAAATCCAAATGTCTGG	PRKX	ENSG00000183943	-0.01361849778988855	[1073]	[957,1441,1317,1269]	0	hSpCas9	negative selection	5871450
3674662	3674685	X	-	27260156	COLO741	viability	CGACGTCATCCGCCTAAAGCAGG	PRKX	ENSG00000183943	0.1226745603705266	[1416]	[2258,1772,1905]	2	hSpCas9	negative selection	5928441
3655338	3655361	X	+	27260156	COLO741	viability	TAGCTGAAGAGCTCGCCGCCCGG	PRKX	ENSG00000183943	-0.39487086275179917	[1054]	[1160,959,967]	-7	hSpCas9	negative selection	5928442
3674650	3674673	X	+	27260156	COLO741	viability	GTACGTGTTGCTCCTGCTTTAGG	PRKX	ENSG00000183943	0.40990718533492576	[760]	[1332,1194,1343]	8	hSpCas9	negative selection	5928443
3655180	3655203	X	-	27260156	COLO741	viability	GGATGGCCACATTAAGCTCACGG	PRKX	ENSG00000183943	-0.938194780608707	[134]	[100,82,86]	-9	hSpCas9	negative selection	5992699
3626432	3626455	X	-	27260156	COLO741	viability	AATAGATTTCCCCAGACATTTGG	PRKX	ENSG00000183943	0.4110848154010618	[578]	[1084,926,947]	8	hSpCas9	negative selection	5992700
3626421	3626444	X	+	27260156	COLO741	viability	TACATGGAAATCCAAATGTCTGG	PRKX	ENSG00000183943	-0.16928038651884125	[1073]	[1285,1133,1241]	-4	hSpCas9	negative selection	5992701
3674662	3674685	X	-	27260156	CAL120	viability	CGACGTCATCCGCCTAAAGCAGG	PRKX	ENSG00000183943	0.2105827727104772	[1416]	[2560,2116,1529]	3	hSpCas9	negative selection	6049692
3655338	3655361	X	+	27260156	CAL120	viability	TAGCTGAAGAGCTCGCCGCCCGG	PRKX	ENSG00000183943	-0.24987235683472153	[1054]	[1209,1089,1028]	-4	hSpCas9	negative selection	6049693
3674650	3674673	X	+	27260156	CAL120	viability	GTACGTGTTGCTCCTGCTTTAGG	PRKX	ENSG00000183943	0.4836928589739825	[760]	[1459,1128,1401]	7	hSpCas9	negative selection	6049694
3655180	3655203	X	-	27260156	CAL120	viability	GGATGGCCACATTAAGCTCACGG	PRKX	ENSG00000183943	-1.395815178207034	[134]	[50,42,94]	-9	hSpCas9	negative selection	6113950
3626432	3626455	X	-	27260156	CAL120	viability	AATAGATTTCCCCAGACATTTGG	PRKX	ENSG00000183943	0.5849708921847702	[578]	[1095,1060,1086]	8	hSpCas9	negative selection	6113951
3626421	3626444	X	+	27260156	CAL120	viability	TACATGGAAATCCAAATGTCTGG	PRKX	ENSG00000183943	-0.06406764154780675	[1073]	[1040,1031,1717]	-1	hSpCas9	negative selection	6113952
3674662	3674685	X	-	27260156	CADOES1	viability	CGACGTCATCCGCCTAAAGCAGG	PRKX	ENSG00000183943	0.31687521906580285	[1416]	[1333,1651,1586,2007]	5	hSpCas9	negative selection	6170943
3655338	3655361	X	+	27260156	CADOES1	viability	TAGCTGAAGAGCTCGCCGCCCGG	PRKX	ENSG00000183943	-0.35856778277232626	[1054]	[663,894,728,773]	-6	hSpCas9	negative selection	6170944
3674650	3674673	X	+	27260156	CADOES1	viability	GTACGTGTTGCTCCTGCTTTAGG	PRKX	ENSG00000183943	0.5061692176590974	[760]	[870,833,1102,1220]	8	hSpCas9	negative selection	6170945
3655180	3655203	X	-	27260156	CADOES1	viability	GGATGGCCACATTAAGCTCACGG	PRKX	ENSG00000183943	-1.6178993412502487	[134]	[48,26,35,51]	-9	hSpCas9	negative selection	6235201
3626432	3626455	X	-	27260156	CADOES1	viability	AATAGATTTCCCCAGACATTTGG	PRKX	ENSG00000183943	0.16920251570276373	[578]	[578,627,511,706]	3	hSpCas9	negative selection	6235202
3626421	3626444	X	+	27260156	CADOES1	viability	TACATGGAAATCCAAATGTCTGG	PRKX	ENSG00000183943	-0.09694216521484611	[1073]	[958,792,1010,973]	-2	hSpCas9	negative selection	6235203
3674662	3674685	X	-	27260156	EWS502	viability	CGACGTCATCCGCCTAAAGCAGG	PRKX	ENSG00000183943	0.14729877253490753	[1416]	[1513,1554,1735,1875]	2	hSpCas9	negative selection	6292194
3655338	3655361	X	+	27260156	EWS502	viability	TAGCTGAAGAGCTCGCCGCCCGG	PRKX	ENSG00000183943	-0.498997817117087	[1054]	[593,901,836,850]	-7	hSpCas9	negative selection	6292195
3674650	3674673	X	+	27260156	EWS502	viability	GTACGTGTTGCTCCTGCTTTAGG	PRKX	ENSG00000183943	0.5007438785185586	[760]	[1075,1016,1245,1239]	8	hSpCas9	negative selection	6292196
3655180	3655203	X	-	27260156	EWS502	viability	GGATGGCCACATTAAGCTCACGG	PRKX	ENSG00000183943	-0.8899344682701129	[134]	[26,132,60,91]	-8	hSpCas9	negative selection	6356452
3626432	3626455	X	-	27260156	EWS502	viability	AATAGATTTCCCCAGACATTTGG	PRKX	ENSG00000183943	0.836457658891603	[578]	[931,910,1254,1323]	9	hSpCas9	negative selection	6356453
3626421	3626444	X	+	27260156	EWS502	viability	TACATGGAAATCCAAATGTCTGG	PRKX	ENSG00000183943	-0.07664152553358683	[1073]	[1101,934,963,1328]	-1	hSpCas9	negative selection	6356454
3674662	3674685	X	-	27260156	EW8	viability	CGACGTCATCCGCCTAAAGCAGG	PRKX	ENSG00000183943	0.13236477789935286	[1416]	[1329,1327,1148,1250]	2	hSpCas9	negative selection	6413445
3655338	3655361	X	+	27260156	EW8	viability	TAGCTGAAGAGCTCGCCGCCCGG	PRKX	ENSG00000183943	-0.0744818012800903	[1054]	[855,902,746,755]	-1	hSpCas9	negative selection	6413446
3674650	3674673	X	+	27260156	EW8	viability	GTACGTGTTGCTCCTGCTTTAGG	PRKX	ENSG00000183943	0.32809905045656074	[760]	[882,829,631,785]	6	hSpCas9	negative selection	6413447
3655180	3655203	X	-	27260156	EW8	viability	GGATGGCCACATTAAGCTCACGG	PRKX	ENSG00000183943	-1.7349912714296856	[134]	[9,62,32,22]	-9	hSpCas9	negative selection	6477703
3626432	3626455	X	-	27260156	EW8	viability	AATAGATTTCCCCAGACATTTGG	PRKX	ENSG00000183943	0.5968562434059322	[578]	[810,601,764,659]	9	hSpCas9	negative selection	6477704
3626421	3626444	X	+	27260156	EW8	viability	TACATGGAAATCCAAATGTCTGG	PRKX	ENSG00000183943	-0.053922920637079486	[1073]	[927,917,838,676]	-1	hSpCas9	negative selection	6477705
3674662	3674685	X	-	27260156	CORL105	viability	CGACGTCATCCGCCTAAAGCAGG	PRKX	ENSG00000183943	0.23582404829806292	[1416]	[2082,1750,2114,1897]	4	hSpCas9	negative selection	6534696
3655338	3655361	X	+	27260156	CORL105	viability	TAGCTGAAGAGCTCGCCGCCCGG	PRKX	ENSG00000183943	-0.31996307062053453	[1054]	[1126,885,1100,867]	-5	hSpCas9	negative selection	6534697
3674650	3674673	X	+	27260156	CORL105	viability	GTACGTGTTGCTCCTGCTTTAGG	PRKX	ENSG00000183943	0.3602184191245307	[760]	[1243,1071,1300,986]	6	hSpCas9	negative selection	6534698
3655180	3655203	X	-	27260156	CORL105	viability	GGATGGCCACATTAAGCTCACGG	PRKX	ENSG00000183943	-1.18259422427684	[134]	[61,64,92,61]	-9	hSpCas9	negative selection	6598954
3626432	3626455	X	-	27260156	CORL105	viability	AATAGATTTCCCCAGACATTTGG	PRKX	ENSG00000183943	0.3432097136849773	[578]	[850,829,907,857]	6	hSpCas9	negative selection	6598955
3626421	3626444	X	+	27260156	CORL105	viability	TACATGGAAATCCAAATGTCTGG	PRKX	ENSG00000183943	-0.37382052829440227	[1073]	[1038,916,1092,854]	-6	hSpCas9	negative selection	6598956
3674662	3674685	X	-	27260156	HS294T	viability	CGACGTCATCCGCCTAAAGCAGG	PRKX	ENSG00000183943	0.47379662261127775	[1416]	[673,744,784,862]	6	hSpCas9	negative selection	6655947
3655338	3655361	X	+	27260156	HS294T	viability	TAGCTGAAGAGCTCGCCGCCCGG	PRKX	ENSG00000183943	-0.15754220940505403	[1054]	[270,237,401,603]	-2	hSpCas9	negative selection	6655948
3674650	3674673	X	+	27260156	HS294T	viability	GTACGTGTTGCTCCTGCTTTAGG	PRKX	ENSG00000183943	0.6712900655849933	[760]	[529,380,348,637]	8	hSpCas9	negative selection	6655949
3655180	3655203	X	-	27260156	HS294T	viability	GGATGGCCACATTAAGCTCACGG	PRKX	ENSG00000183943	-0.7687730284184184	[134]	[40,10,19,53]	-8	hSpCas9	negative selection	6720205
3626432	3626455	X	-	27260156	HS294T	viability	AATAGATTTCCCCAGACATTTGG	PRKX	ENSG00000183943	0.14404319930472276	[578]	[203,237,264,293]	2	hSpCas9	negative selection	6720206
3626421	3626444	X	+	27260156	HS294T	viability	TACATGGAAATCCAAATGTCTGG	PRKX	ENSG00000183943	-0.06998455822963412	[1073]	[231,320,533,535]	-1	hSpCas9	negative selection	6720207
3674662	3674685	X	-	27260156	HCC44	viability	CGACGTCATCCGCCTAAAGCAGG	PRKX	ENSG00000183943	0.2174549314356533	[1416]	[1996,1407,1904,2200]	3	hSpCas9	negative selection	6777198
3655338	3655361	X	+	27260156	HCC44	viability	TAGCTGAAGAGCTCGCCGCCCGG	PRKX	ENSG00000183943	-0.35787768961711364	[1054]	[1072,564,1002,1145]	-5	hSpCas9	negative selection	6777199
3674650	3674673	X	+	27260156	HCC44	viability	GTACGTGTTGCTCCTGCTTTAGG	PRKX	ENSG00000183943	0.5650289546008015	[760]	[1491,1063,1500,1119]	8	hSpCas9	negative selection	6777200
3655180	3655203	X	-	27260156	HCC44	viability	GGATGGCCACATTAAGCTCACGG	PRKX	ENSG00000183943	-1.4576465508813843	[134]	[39,82,79,18]	-9	hSpCas9	negative selection	6841456
3626432	3626455	X	-	27260156	HCC44	viability	AATAGATTTCCCCAGACATTTGG	PRKX	ENSG00000183943	0.5854432640839159	[578]	[810,750,1512,956]	8	hSpCas9	negative selection	6841457
3626421	3626444	X	+	27260156	HCC44	viability	TACATGGAAATCCAAATGTCTGG	PRKX	ENSG00000183943	0.015335151369637368	[1073]	[1325,992,1214,1400]	0	hSpCas9	negative selection	6841458
3674662	3674685	X	-	27260156	G402	viability	CGACGTCATCCGCCTAAAGCAGG	PRKX	ENSG00000183943	0.09847018392898788	[1416]	[1820,1993,1938,1656]	1	hSpCas9	negative selection	6898449
3655338	3655361	X	+	27260156	G402	viability	TAGCTGAAGAGCTCGCCGCCCGG	PRKX	ENSG00000183943	-0.24054310511308408	[1054]	[1399,837,1174,976]	-3	hSpCas9	negative selection	6898450
3674650	3674673	X	+	27260156	G402	viability	GTACGTGTTGCTCCTGCTTTAGG	PRKX	ENSG00000183943	0.8370994100994812	[760]	[1225,1925,1495,1920]	9	hSpCas9	negative selection	6898451
3655180	3655203	X	-	27260156	G402	viability	GGATGGCCACATTAAGCTCACGG	PRKX	ENSG00000183943	0.8084712820539878	[134]	[99,104,70,812]	8	hSpCas9	negative selection	6962707
3626432	3626455	X	-	27260156	G402	viability	AATAGATTTCCCCAGACATTTGG	PRKX	ENSG00000183943	0.5443808886237678	[578]	[773,1141,1100,1067]	6	hSpCas9	negative selection	6962708
3626421	3626444	X	+	27260156	G402	viability	TACATGGAAATCCAAATGTCTGG	PRKX	ENSG00000183943	0.12260155439116383	[1073]	[2152,1533,878,1254]	1	hSpCas9	negative selection	6962709
3674662	3674685	X	-	27260156	L33	viability	CGACGTCATCCGCCTAAAGCAGG	PRKX	ENSG00000183943	0.20901366891593387	[1416]	[1640,640,979,1784]	4	hSpCas9	negative selection	7019700
3655338	3655361	X	+	27260156	L33	viability	TAGCTGAAGAGCTCGCCGCCCGG	PRKX	ENSG00000183943	-0.323660110051042	[1054]	[839,404,465,801]	-6	hSpCas9	negative selection	7019701
3674650	3674673	X	+	27260156	L33	viability	GTACGTGTTGCTCCTGCTTTAGG	PRKX	ENSG00000183943	0.4207987678811854	[760]	[837,478,656,1026]	8	hSpCas9	negative selection	7019702
3655180	3655203	X	-	27260156	L33	viability	GGATGGCCACATTAAGCTCACGG	PRKX	ENSG00000183943	-1.9780798544108908	[134]	[44,12,16,32]	-9	hSpCas9	negative selection	7083958
3626432	3626455	X	-	27260156	L33	viability	AATAGATTTCCCCAGACATTTGG	PRKX	ENSG00000183943	0.3706181687491579	[578]	[718,312,450,793]	7	hSpCas9	negative selection	7083959
3626421	3626444	X	+	27260156	L33	viability	TACATGGAAATCCAAATGTCTGG	PRKX	ENSG00000183943	-0.07975878360925548	[1073]	[1115,467,553,922]	-2	hSpCas9	negative selection	7083960
3674662	3674685	X	-	27260156	K562	viability	CGACGTCATCCGCCTAAAGCAGG	PRKX	ENSG00000183943	0.21680308632488177	[1416]	[2173,1076,1188,1439]	2	hSpCas9	negative selection	7140951
3655338	3655361	X	+	27260156	K562	viability	TAGCTGAAGAGCTCGCCGCCCGG	PRKX	ENSG00000183943	-0.3039865881827756	[1054]	[1312,751,371,650]	-4	hSpCas9	negative selection	7140952
3674650	3674673	X	+	27260156	K562	viability	GTACGTGTTGCTCCTGCTTTAGG	PRKX	ENSG00000183943	0.6468533520177208	[760]	[697,1301,919,1263]	8	hSpCas9	negative selection	7140953
3655180	3655203	X	-	27260156	K562	viability	GGATGGCCACATTAAGCTCACGG	PRKX	ENSG00000183943	-1.257554187456735	[134]	[60,10,66,58]	-8	hSpCas9	negative selection	7205209
3626432	3626455	X	-	27260156	K562	viability	AATAGATTTCCCCAGACATTTGG	PRKX	ENSG00000183943	0.7583419453068715	[578]	[643,884,563,1309]	8	hSpCas9	negative selection	7205210
3626421	3626444	X	+	27260156	K562	viability	TACATGGAAATCCAAATGTCTGG	PRKX	ENSG00000183943	0.16029541869481045	[1073]	[1097,883,1361,921]	2	hSpCas9	negative selection	7205211
3674662	3674685	X	-	27260156	HT29	viability	CGACGTCATCCGCCTAAAGCAGG	PRKX	ENSG00000183943	0.2332409004602498	[1416]	[2200,2294,2191,1498]	4	hSpCas9	negative selection	7262202
3655338	3655361	X	+	27260156	HT29	viability	TAGCTGAAGAGCTCGCCGCCCGG	PRKX	ENSG00000183943	-0.34272940811887564	[1054]	[1230,922,1212,716]	-6	hSpCas9	negative selection	7262203
3674650	3674673	X	+	27260156	HT29	viability	GTACGTGTTGCTCCTGCTTTAGG	PRKX	ENSG00000183943	0.40819435070415133	[760]	[1396,1328,1030,1172]	7	hSpCas9	negative selection	7262204
3655180	3655203	X	-	27260156	HT29	viability	GGATGGCCACATTAAGCTCACGG	PRKX	ENSG00000183943	-0.8260164443546565	[134]	[121,111,95,48]	-8	hSpCas9	negative selection	7326460
3626432	3626455	X	-	27260156	HT29	viability	AATAGATTTCCCCAGACATTTGG	PRKX	ENSG00000183943	0.42208748776106464	[578]	[847,956,1107,856]	7	hSpCas9	negative selection	7326461
3626421	3626444	X	+	27260156	HT29	viability	TACATGGAAATCCAAATGTCTGG	PRKX	ENSG00000183943	-0.02146764546001445	[1073]	[1340,1426,1294,1110]	0	hSpCas9	negative selection	7326462
3674662	3674685	X	-	27260156	MHHES1	viability	CGACGTCATCCGCCTAAAGCAGG	PRKX	ENSG00000183943	0.3718734543786242	[1416]	[2733,1997,1856,1766]	6	hSpCas9	negative selection	7383453
3655338	3655361	X	+	27260156	MHHES1	viability	TAGCTGAAGAGCTCGCCGCCCGG	PRKX	ENSG00000183943	-0.2763257944970313	[1054]	[1005,816,1344,771]	-5	hSpCas9	negative selection	7383454
3674650	3674673	X	+	27260156	MHHES1	viability	GTACGTGTTGCTCCTGCTTTAGG	PRKX	ENSG00000183943	0.38247263386763486	[760]	[1241,1407,955,925]	7	hSpCas9	negative selection	7383455
3655180	3655203	X	-	27260156	MHHES1	viability	GGATGGCCACATTAAGCTCACGG	PRKX	ENSG00000183943	-0.753046796115916	[134]	[70,159,126,21]	-8	hSpCas9	negative selection	7447711
3626432	3626455	X	-	27260156	MHHES1	viability	AATAGATTTCCCCAGACATTTGG	PRKX	ENSG00000183943	0.27947382885321803	[578]	[768,844,911,656]	5	hSpCas9	negative selection	7447712
3626421	3626444	X	+	27260156	MHHES1	viability	TACATGGAAATCCAAATGTCTGG	PRKX	ENSG00000183943	-0.1884214656771499	[1073]	[1101,1209,1387,642]	-4	hSpCas9	negative selection	7447713
3674662	3674685	X	-	27260156	MEWO	viability	CGACGTCATCCGCCTAAAGCAGG	PRKX	ENSG00000183943	0.10108600579962679	[1416]	[1444,1603,1219]	2	hSpCas9	negative selection	7504704
3655338	3655361	X	+	27260156	MEWO	viability	TAGCTGAAGAGCTCGCCGCCCGG	PRKX	ENSG00000183943	-0.30900453950349993	[1054]	[799,717,872]	-6	hSpCas9	negative selection	7504705
3674650	3674673	X	+	27260156	MEWO	viability	GTACGTGTTGCTCCTGCTTTAGG	PRKX	ENSG00000183943	0.4542316818923461	[760]	[1084,829,1032]	8	hSpCas9	negative selection	7504706
3655180	3655203	X	-	27260156	MEWO	viability	GGATGGCCACATTAAGCTCACGG	PRKX	ENSG00000183943	-1.549241298501937	[134]	[20,76,26]	-9	hSpCas9	negative selection	7568962
3626432	3626455	X	-	27260156	MEWO	viability	AATAGATTTCCCCAGACATTTGG	PRKX	ENSG00000183943	0.08672122475086352	[578]	[549,519,650]	2	hSpCas9	negative selection	7568963
3626421	3626444	X	+	27260156	MEWO	viability	TACATGGAAATCCAAATGTCTGG	PRKX	ENSG00000183943	-0.09049492498952261	[1073]	[927,913,985]	-2	hSpCas9	negative selection	7568964
3674662	3674685	X	-	27260156	LNCAPCLONEFGC	viability	CGACGTCATCCGCCTAAAGCAGG	PRKX	ENSG00000183943	0.29574671089984594	[1416]	[1344,1494,1768,1730]	4	hSpCas9	negative selection	7625955
3655338	3655361	X	+	27260156	LNCAPCLONEFGC	viability	TAGCTGAAGAGCTCGCCGCCCGG	PRKX	ENSG00000183943	0.02858894088755992	[1054]	[893,869,1088,1070]	0	hSpCas9	negative selection	7625956
3674650	3674673	X	+	27260156	LNCAPCLONEFGC	viability	GTACGTGTTGCTCCTGCTTTAGG	PRKX	ENSG00000183943	0.7282091250968915	[760]	[1023,1140,1313,1115]	9	hSpCas9	negative selection	7625957
3655180	3655203	X	-	27260156	LNCAPCLONEFGC	viability	GGATGGCCACATTAAGCTCACGG	PRKX	ENSG00000183943	-1.3636574686772251	[134]	[25,25,27,108]	-9	hSpCas9	negative selection	7690213
3626432	3626455	X	-	27260156	LNCAPCLONEFGC	viability	AATAGATTTCCCCAGACATTTGG	PRKX	ENSG00000183943	0.501452464981852	[578]	[615,662,983,749]	7	hSpCas9	negative selection	7690214
3626421	3626444	X	+	27260156	LNCAPCLONEFGC	viability	TACATGGAAATCCAAATGTCTGG	PRKX	ENSG00000183943	-0.25871448432497457	[1073]	[919,645,926,784]	-4	hSpCas9	negative selection	7690215
3674662	3674685	X	-	27260156	PANC0327	viability	CGACGTCATCCGCCTAAAGCAGG	PRKX	ENSG00000183943	0.0007579934180257375	[1416]	[1131,1366,1317,1195]	0	hSpCas9	negative selection	7747206
3655338	3655361	X	+	27260156	PANC0327	viability	TAGCTGAAGAGCTCGCCGCCCGG	PRKX	ENSG00000183943	-0.4393350310789088	[1054]	[711,769,718,554]	-6	hSpCas9	negative selection	7747207
3674650	3674673	X	+	27260156	PANC0327	viability	GTACGTGTTGCTCCTGCTTTAGG	PRKX	ENSG00000183943	0.7115712459496059	[760]	[1463,870,896,1254]	8	hSpCas9	negative selection	7747208
3655180	3655203	X	-	27260156	PANC0327	viability	GGATGGCCACATTAAGCTCACGG	PRKX	ENSG00000183943	-0.014428359307156358	[134]	[15,17,406,38]	0	hSpCas9	negative selection	7811464
3626432	3626455	X	-	27260156	PANC0327	viability	AATAGATTTCCCCAGACATTTGG	PRKX	ENSG00000183943	0.14439838282783085	[578]	[404,608,560,679]	2	hSpCas9	negative selection	7811465
3626421	3626444	X	+	27260156	PANC0327	viability	TACATGGAAATCCAAATGTCTGG	PRKX	ENSG00000183943	-0.37668437461774573	[1073]	[1045,520,665,758]	-5	hSpCas9	negative selection	7811466
3674662	3674685	X	-	27260156	NCIH2009	viability	CGACGTCATCCGCCTAAAGCAGG	PRKX	ENSG00000183943	0.4457206958513229	[1416]	[3100,2789,2271]	6	hSpCas9	negative selection	7868457
3655338	3655361	X	+	27260156	NCIH2009	viability	TAGCTGAAGAGCTCGCCGCCCGG	PRKX	ENSG00000183943	-0.04960582460304175	[1054]	[1700,1304,1320]	0	hSpCas9	negative selection	7868458
3674650	3674673	X	+	27260156	NCIH2009	viability	GTACGTGTTGCTCCTGCTTTAGG	PRKX	ENSG00000183943	0.35942633844024174	[760]	[1693,1530,926]	5	hSpCas9	negative selection	7868459
3655180	3655203	X	-	27260156	NCIH2009	viability	GGATGGCCACATTAAGCTCACGG	PRKX	ENSG00000183943	-1.1819301228677623	[134]	[122,90,42]	-8	hSpCas9	negative selection	7932715
3626432	3626455	X	-	27260156	NCIH2009	viability	AATAGATTTCCCCAGACATTTGG	PRKX	ENSG00000183943	0.2791866771310155	[578]	[1089,1078,793]	4	hSpCas9	negative selection	7932716
3626421	3626444	X	+	27260156	NCIH2009	viability	TACATGGAAATCCAAATGTCTGG	PRKX	ENSG00000183943	-0.14528282098129264	[1073]	[1412,981,1690]	-2	hSpCas9	negative selection	7932717
3674662	3674685	X	-	27260156	NCIH1373	viability	CGACGTCATCCGCCTAAAGCAGG	PRKX	ENSG00000183943	0.9308550522459904	[1416]	[3271,2467,3514,767]	8	hSpCas9	negative selection	7989708
3655338	3655361	X	+	27260156	NCIH1373	viability	TAGCTGAAGAGCTCGCCGCCCGG	PRKX	ENSG00000183943	0.41726992460408874	[1054]	[1846,1565,1198,461]	4	hSpCas9	negative selection	7989709
3674650	3674673	X	+	27260156	NCIH1373	viability	GTACGTGTTGCTCCTGCTTTAGG	PRKX	ENSG00000183943	0.8875438865619684	[760]	[2558,1432,1233,323]	8	hSpCas9	negative selection	7989710
3655180	3655203	X	-	27260156	NCIH1373	viability	GGATGGCCACATTAAGCTCACGG	PRKX	ENSG00000183943	-1.3025352151524918	[134]	[125,24,85,4]	-8	hSpCas9	negative selection	8053966
3626432	3626455	X	-	27260156	NCIH1373	viability	AATAGATTTCCCCAGACATTTGG	PRKX	ENSG00000183943	0.6059818983886937	[578]	[1091,866,955,279]	6	hSpCas9	negative selection	8053967
3626421	3626444	X	+	27260156	NCIH1373	viability	TACATGGAAATCCAAATGTCTGG	PRKX	ENSG00000183943	-0.01726723400302177	[1073]	[1600,784,1595,222]	0	hSpCas9	negative selection	8053968
3674662	3674685	X	-	27260156	PATU8902	viability	CGACGTCATCCGCCTAAAGCAGG	PRKX	ENSG00000183943	0.5090665517777548	[1416]	[2561,2723,2352,3813]	5	hSpCas9	negative selection	8110959
3655338	3655361	X	+	27260156	PATU8902	viability	TAGCTGAAGAGCTCGCCGCCCGG	PRKX	ENSG00000183943	0.3977209527349628	[1054]	[1921,1635,1846,2399]	4	hSpCas9	negative selection	8110960
3674650	3674673	X	+	27260156	PATU8902	viability	GTACGTGTTGCTCCTGCTTTAGG	PRKX	ENSG00000183943	0.9152640563282631	[760]	[2056,2182,1816,1964]	8	hSpCas9	negative selection	8110961
3655180	3655203	X	-	27260156	PATU8902	viability	GGATGGCCACATTAAGCTCACGG	PRKX	ENSG00000183943	-1.2095798432929852	[134]	[32,35,133,111]	-8	hSpCas9	negative selection	8175217
3626432	3626455	X	-	27260156	PATU8902	viability	AATAGATTTCCCCAGACATTTGG	PRKX	ENSG00000183943	0.49816943730760366	[578]	[831,1727,903,1150]	5	hSpCas9	negative selection	8175218
3626421	3626444	X	+	27260156	PATU8902	viability	TACATGGAAATCCAAATGTCTGG	PRKX	ENSG00000183943	-0.16934817361358823	[1073]	[1478,1809,773,1398]	-2	hSpCas9	negative selection	8175219
3674662	3674685	X	-	27260156	PANC1	viability	CGACGTCATCCGCCTAAAGCAGG	PRKX	ENSG00000183943	0.21962940584801927	[1416]	[1499,1873,1265,1141]	3	hSpCas9	negative selection	8232210
3655338	3655361	X	+	27260156	PANC1	viability	TAGCTGAAGAGCTCGCCGCCCGG	PRKX	ENSG00000183943	-0.24505478000415892	[1054]	[500,1145,715,765]	-4	hSpCas9	negative selection	8232211
3674650	3674673	X	+	27260156	PANC1	viability	GTACGTGTTGCTCCTGCTTTAGG	PRKX	ENSG00000183943	0.4086405684130471	[760]	[812,1008,910,769]	6	hSpCas9	negative selection	8232212
3655180	3655203	X	-	27260156	PANC1	viability	GGATGGCCACATTAAGCTCACGG	PRKX	ENSG00000183943	-1.1965604293925687	[134]	[30,51,19,91]	-9	hSpCas9	negative selection	8296468
3626432	3626455	X	-	27260156	PANC1	viability	AATAGATTTCCCCAGACATTTGG	PRKX	ENSG00000183943	0.4820926105174451	[578]	[551,836,805,617]	7	hSpCas9	negative selection	8296469
3626421	3626444	X	+	27260156	PANC1	viability	TACATGGAAATCCAAATGTCTGG	PRKX	ENSG00000183943	-0.027771991329170742	[1073]	[687,1487,898,689]	0	hSpCas9	negative selection	8296470
3674662	3674685	X	-	27260156	PANC0813	viability	CGACGTCATCCGCCTAAAGCAGG	PRKX	ENSG00000183943	0.35562118633073125	[1416]	[2650,1886,2329,1719]	6	hSpCas9	negative selection	8353461
3655338	3655361	X	+	27260156	PANC0813	viability	TAGCTGAAGAGCTCGCCGCCCGG	PRKX	ENSG00000183943	-0.1937597223257448	[1054]	[1246,1243,1084,787]	-3	hSpCas9	negative selection	8353462
3674650	3674673	X	+	27260156	PANC0813	viability	GTACGTGTTGCTCCTGCTTTAGG	PRKX	ENSG00000183943	0.2493935744455944	[760]	[1167,1026,1256,820]	4	hSpCas9	negative selection	8353463
3655180	3655203	X	-	27260156	PANC0813	viability	GGATGGCCACATTAAGCTCACGG	PRKX	ENSG00000183943	-0.9373915347423571	[134]	[83,136,28,80]	-8	hSpCas9	negative selection	8417719
3626432	3626455	X	-	27260156	PANC0813	viability	AATAGATTTCCCCAGACATTTGG	PRKX	ENSG00000183943	0.6109323806175434	[578]	[1311,806,1064,996]	8	hSpCas9	negative selection	8417720
3626421	3626444	X	+	27260156	PANC0813	viability	TACATGGAAATCCAAATGTCTGG	PRKX	ENSG00000183943	-0.25986154079908985	[1073]	[1003,1200,1179,835]	-4	hSpCas9	negative selection	8417721
3674662	3674685	X	-	27260156	RDES	viability	CGACGTCATCCGCCTAAAGCAGG	PRKX	ENSG00000183943	0.21237571058953253	[1416]	[1590,1854,2176,1958]	3	hSpCas9	negative selection	8474712
3655338	3655361	X	+	27260156	RDES	viability	TAGCTGAAGAGCTCGCCGCCCGG	PRKX	ENSG00000183943	-0.20776727479649137	[1054]	[932,959,1149,1183]	-4	hSpCas9	negative selection	8474713
3674650	3674673	X	+	27260156	RDES	viability	GTACGTGTTGCTCCTGCTTTAGG	PRKX	ENSG00000183943	0.619690442715391	[760]	[1079,1304,1270,1811]	8	hSpCas9	negative selection	8474714
3655180	3655203	X	-	27260156	RDES	viability	GGATGGCCACATTAAGCTCACGG	PRKX	ENSG00000183943	-1.4857325812299942	[134]	[54,68,51,39]	-9	hSpCas9	negative selection	8538970
3626432	3626455	X	-	27260156	RDES	viability	AATAGATTTCCCCAGACATTTGG	PRKX	ENSG00000183943	0.47546667581974955	[578]	[651,859,1105,1168]	7	hSpCas9	negative selection	8538971
3626421	3626444	X	+	27260156	RDES	viability	TACATGGAAATCCAAATGTCTGG	PRKX	ENSG00000183943	-0.26642944741652974	[1073]	[1060,890,984,1158]	-4	hSpCas9	negative selection	8538972
3674662	3674685	X	-	27260156	PC3	viability	CGACGTCATCCGCCTAAAGCAGG	PRKX	ENSG00000183943	0.21836240472726764	[1416]	[1030,1506,2671,1890]	5	hSpCas9	negative selection	8595963
3655338	3655361	X	+	27260156	PC3	viability	TAGCTGAAGAGCTCGCCGCCCGG	PRKX	ENSG00000183943	-0.21007286468233255	[1054]	[572,1030,1680,692]	-5	hSpCas9	negative selection	8595964
3674650	3674673	X	+	27260156	PC3	viability	GTACGTGTTGCTCCTGCTTTAGG	PRKX	ENSG00000183943	0.48173312679712554	[760]	[798,1018,1943,802]	8	hSpCas9	negative selection	8595965
3655180	3655203	X	-	27260156	PC3	viability	GGATGGCCACATTAAGCTCACGG	PRKX	ENSG00000183943	-1.5757081233718264	[134]	[8,95,19,56]	-9	hSpCas9	negative selection	8660221
3626432	3626455	X	-	27260156	PC3	viability	AATAGATTTCCCCAGACATTTGG	PRKX	ENSG00000183943	0.6196769166200677	[578]	[652,1031,973,914]	9	hSpCas9	negative selection	8660222
3626421	3626444	X	+	27260156	PC3	viability	TACATGGAAATCCAAATGTCTGG	PRKX	ENSG00000183943	-0.1483512499374433	[1073]	[554,830,1601,1236]	-3	hSpCas9	negative selection	8660223
3674662	3674685	X	-	27260156	PATU8988T	viability	CGACGTCATCCGCCTAAAGCAGG	PRKX	ENSG00000183943	0.08499694246201073	[1416]	[1232,1554,1546,1484]	1	hSpCas9	negative selection	8717214
3655338	3655361	X	+	27260156	PATU8988T	viability	TAGCTGAAGAGCTCGCCGCCCGG	PRKX	ENSG00000183943	-0.15686369081428175	[1054]	[1118,703,1056,741]	-3	hSpCas9	negative selection	8717215
3674650	3674673	X	+	27260156	PATU8988T	viability	GTACGTGTTGCTCCTGCTTTAGG	PRKX	ENSG00000183943	0.3570745346276031	[760]	[831,837,944,1159]	6	hSpCas9	negative selection	8717216
3655180	3655203	X	-	27260156	PATU8988T	viability	GGATGGCCACATTAAGCTCACGG	PRKX	ENSG00000183943	-1.8173522660126415	[134]	[26,24,14,83]	-9	hSpCas9	negative selection	8781472
3626432	3626455	X	-	27260156	PATU8988T	viability	AATAGATTTCCCCAGACATTTGG	PRKX	ENSG00000183943	0.6901263538990311	[578]	[1028,921,871,779]	9	hSpCas9	negative selection	8781473
3626421	3626444	X	+	27260156	PATU8988T	viability	TACATGGAAATCCAAATGTCTGG	PRKX	ENSG00000183943	-0.3075618136595326	[1073]	[696,1065,688,932]	-5	hSpCas9	negative selection	8781474
3674662	3674685	X	-	27260156	T47D	viability	CGACGTCATCCGCCTAAAGCAGG	PRKX	ENSG00000183943	0.17110146878599086	[1416]	[2059,1727,1761,1898]	3	hSpCas9	negative selection	8838465
3655338	3655361	X	+	27260156	T47D	viability	TAGCTGAAGAGCTCGCCGCCCGG	PRKX	ENSG00000183943	-0.1613697768025435	[1054]	[1240,948,1057,1163]	-4	hSpCas9	negative selection	8838466
3674650	3674673	X	+	27260156	T47D	viability	GTACGTGTTGCTCCTGCTTTAGG	PRKX	ENSG00000183943	0.5278239489812023	[760]	[1345,1150,1237,1392]	9	hSpCas9	negative selection	8838467
3655180	3655203	X	-	27260156	T47D	viability	GGATGGCCACATTAAGCTCACGG	PRKX	ENSG00000183943	-1.1774184035707849	[134]	[75,56,58,87]	-9	hSpCas9	negative selection	8902723
3626432	3626455	X	-	27260156	T47D	viability	AATAGATTTCCCCAGACATTTGG	PRKX	ENSG00000183943	0.4510604116628192	[578]	[854,944,905,981]	8	hSpCas9	negative selection	8902724
3626421	3626444	X	+	27260156	T47D	viability	TACATGGAAATCCAAATGTCTGG	PRKX	ENSG00000183943	-0.07266555601181501	[1073]	[1162,1244,1097,1250]	-2	hSpCas9	negative selection	8902725
3674662	3674685	X	-	27260156	SU8686	viability	CGACGTCATCCGCCTAAAGCAGG	PRKX	ENSG00000183943	0.3666868895107085	[1416]	[1517,1477,2116,2280]	6	hSpCas9	negative selection	8959716
3655338	3655361	X	+	27260156	SU8686	viability	TAGCTGAAGAGCTCGCCGCCCGG	PRKX	ENSG00000183943	-0.13768348725994262	[1054]	[789,901,1147,992]	-2	hSpCas9	negative selection	8959717
3674650	3674673	X	+	27260156	SU8686	viability	GTACGTGTTGCTCCTGCTTTAGG	PRKX	ENSG00000183943	0.39913522192091555	[760]	[991,850,964,1218]	6	hSpCas9	negative selection	8959718
3655180	3655203	X	-	27260156	SU8686	viability	GGATGGCCACATTAAGCTCACGG	PRKX	ENSG00000183943	-0.2057871665791613	[134]	[109,93,77,196]	-4	hSpCas9	negative selection	9023974
3626432	3626455	X	-	27260156	SU8686	viability	AATAGATTTCCCCAGACATTTGG	PRKX	ENSG00000183943	0.46343476907689074	[578]	[605,711,934,971]	7	hSpCas9	negative selection	9023975
3626421	3626444	X	+	27260156	SU8686	viability	TACATGGAAATCCAAATGTCTGG	PRKX	ENSG00000183943	0.09068461404551309	[1073]	[1237,898,1326,1077]	1	hSpCas9	negative selection	9023976
3674662	3674685	X	-	27260156	SKES1	viability	CGACGTCATCCGCCTAAAGCAGG	PRKX	ENSG00000183943	0.17746310093606454	[1416]	[1871,1523,1512,1508]	4	hSpCas9	negative selection	9080967
3655338	3655361	X	+	27260156	SKES1	viability	TAGCTGAAGAGCTCGCCGCCCGG	PRKX	ENSG00000183943	-0.23908494764561927	[1054]	[1013,999,829,759]	-5	hSpCas9	negative selection	9080968
3674650	3674673	X	+	27260156	SKES1	viability	GTACGTGTTGCTCCTGCTTTAGG	PRKX	ENSG00000183943	0.47842199519164186	[760]	[1112,1204,942,992]	8	hSpCas9	negative selection	9080969
3655180	3655203	X	-	27260156	SKES1	viability	GGATGGCCACATTAAGCTCACGG	PRKX	ENSG00000183943	-0.8951500957893475	[134]	[110,47,44,85]	-9	hSpCas9	negative selection	9145225
3626432	3626455	X	-	27260156	SKES1	viability	AATAGATTTCCCCAGACATTTGG	PRKX	ENSG00000183943	0.44718102438580476	[578]	[840,808,866,649]	8	hSpCas9	negative selection	9145226
3626421	3626444	X	+	27260156	SKES1	viability	TACATGGAAATCCAAATGTCTGG	PRKX	ENSG00000183943	-0.08018263112873991	[1073]	[1260,1035,936,864]	-2	hSpCas9	negative selection	9145227
3674662	3674685	X	-	27260156	TOV112D	viability	CGACGTCATCCGCCTAAAGCAGG	PRKX	ENSG00000183943	0.12997094369851236	[1416]	[1583,1654,1586,1414]	2	hSpCas9	negative selection	9202218
3655338	3655361	X	+	27260156	TOV112D	viability	TAGCTGAAGAGCTCGCCGCCCGG	PRKX	ENSG00000183943	-0.5071906282849886	[1054]	[769,841,642,743]	-7	hSpCas9	negative selection	9202219
3674650	3674673	X	+	27260156	TOV112D	viability	GTACGTGTTGCTCCTGCTTTAGG	PRKX	ENSG00000183943	0.5778631596966634	[760]	[1296,1177,919,1175]	9	hSpCas9	negative selection	9202220
3655180	3655203	X	-	27260156	TOV112D	viability	GGATGGCCACATTAAGCTCACGG	PRKX	ENSG00000183943	-1.6025237720957064	[134]	[45,59,32,42]	-9	hSpCas9	negative selection	9266476
3626432	3626455	X	-	27260156	TOV112D	viability	AATAGATTTCCCCAGACATTTGG	PRKX	ENSG00000183943	0.415862298896734	[578]	[876,715,764,730]	7	hSpCas9	negative selection	9266477
3626421	3626444	X	+	27260156	TOV112D	viability	TACATGGAAATCCAAATGTCTGG	PRKX	ENSG00000183943	-0.21446528059657988	[1073]	[785,1322,997,691]	-4	hSpCas9	negative selection	9266478
3674662	3674685	X	-	27260156	TC71	viability	CGACGTCATCCGCCTAAAGCAGG	PRKX	ENSG00000183943	0.17967090314904022	[1416]	[1439,1827,1793,1829]	4	hSpCas9	negative selection	9323469
3655338	3655361	X	+	27260156	TC71	viability	TAGCTGAAGAGCTCGCCGCCCGG	PRKX	ENSG00000183943	-0.45676202591479453	[1054]	[795,907,802,787]	-8	hSpCas9	negative selection	9323470
3674650	3674673	X	+	27260156	TC71	viability	GTACGTGTTGCTCCTGCTTTAGG	PRKX	ENSG00000183943	0.3625962499328964	[760]	[948,1111,1227,892]	8	hSpCas9	negative selection	9323471
3655180	3655203	X	-	27260156	TC71	viability	GGATGGCCACATTAAGCTCACGG	PRKX	ENSG00000183943	-0.98416847187047	[134]	[98,71,56,63]	-9	hSpCas9	negative selection	9387727
3626432	3626455	X	-	27260156	TC71	viability	AATAGATTTCCCCAGACATTTGG	PRKX	ENSG00000183943	0.4491770918594692	[578]	[917,714,903,848]	9	hSpCas9	negative selection	9387728
3626421	3626444	X	+	27260156	TC71	viability	TACATGGAAATCCAAATGTCTGG	PRKX	ENSG00000183943	-0.12184496388450428	[1073]	[920,1091,1097,1126]	-3	hSpCas9	negative selection	9387729
3674662	3674685	X	-	27260156	TC32	viability	CGACGTCATCCGCCTAAAGCAGG	PRKX	ENSG00000183943	0.07694223741609774	[1416]	[1086,1242,1720,1651]	1	hSpCas9	negative selection	9444720
3655338	3655361	X	+	27260156	TC32	viability	TAGCTGAAGAGCTCGCCGCCCGG	PRKX	ENSG00000183943	-0.24203939870261937	[1054]	[833,599,1048,953]	-4	hSpCas9	negative selection	9444721
3674650	3674673	X	+	27260156	TC32	viability	GTACGTGTTGCTCCTGCTTTAGG	PRKX	ENSG00000183943	0.36625446067833056	[760]	[841,724,1198,1002]	6	hSpCas9	negative selection	9444722
3655180	3655203	X	-	27260156	TC32	viability	GGATGGCCACATTAAGCTCACGG	PRKX	ENSG00000183943	-1.2412717915924787	[134]	[24,67,62,54]	-9	hSpCas9	negative selection	9508978
3626432	3626455	X	-	27260156	TC32	viability	AATAGATTTCCCCAGACATTTGG	PRKX	ENSG00000183943	0.2465506538311949	[578]	[485,477,955,769]	4	hSpCas9	negative selection	9508979
3626421	3626444	X	+	27260156	TC32	viability	TACATGGAAATCCAAATGTCTGG	PRKX	ENSG00000183943	-0.2018525284877276	[1073]	[750,593,1266,1048]	-4	hSpCas9	negative selection	9508980
3713196	3713219	X	-	27869803	HPAFII	viability after 27 days	GGAGAGCGACTCCCGCAAGGTGG	PRKX	ENSG00000183943	0.5621687450770477	[296]	[175,275,NaN]	4	hSpCas9	negative selection	9608656
3713196	3713219	X	-	27869803	HPAFII	viability after 15 days	GGAGAGCGACTCCCGCAAGGTGG	PRKX	ENSG00000183943	0.664700170139376	[296]	[505,505,NaN]	7	hSpCas9	negative selection	9691105
3713196	3713219	X	-	27869803	ASPC1	viability after 36 days	GGAGAGCGACTCCCGCAAGGTGG	PRKX	ENSG00000183943	-0.14062284707981262	[766]	[176,269,264]	-1	hSpCas9	negative selection	9773554
3713196	3713219	X	-	27869803	PATU8988S	viability after 35 days	GGAGAGCGACTCCCGCAAGGTGG	PRKX	ENSG00000183943	0.12610403763635175	[609]	[319,215,NaN]	1	hSpCas9	negative selection	9856003
3713196	3713219	X	-	27869803	PATU8988S	viability after 31 days	GGAGAGCGACTCCCGCAAGGTGG	PRKX	ENSG00000183943	-0.10627985747872835	[609]	[221,230,NaN]	-1	hSpCas9	negative selection	9938452
3713196	3713219	X	-	27869803	HPAFII	viability after 35 days	GGAGAGCGACTCCCGCAAGGTGG	PRKX	ENSG00000183943	1.3181816408056473	[296]	[198,572,NaN]	8	hSpCas9	negative selection	10020901
3713196	3713219	X	-	27869803	HPAFII	viability after 31 days	GGAGAGCGACTCCCGCAAGGTGG	PRKX	ENSG00000183943	0.9097292397774145	[296]	[159,479,NaN]	6	hSpCas9	negative selection	10103350
3713196	3713219	X	-	28162770	P31FUJ	viability	GGAGAGCGACTCCCGCAAGGTGG	PRKX	ENSG00000183943	0.8987946783688343	[88]	[194]	8	hSpCas9	negative selection	10217233
3713184	3713207	X	+	28162770	P31FUJ	viability	GGGTCTCCTCCGCCACCTTGCGG	PRKX	ENSG00000183943	0.5143113451279104	[764]	[1283]	6	hSpCas9	negative selection	10217234
3615860	3615883	X	-	28162770	P31FUJ	viability	ATGATGTGAAGCATCATCGGTGG	PRKX	ENSG00000183943	-0.23280220441437827	[0]	[0]	-2	hSpCas9	negative selection	10217235
3713074	3713097	X	+	28162770	P31FUJ	viability	CCGCACTCACTCACCCACGGTGG	PRKX	ENSG00000183943	1.0572166425182399	[127]	[312]	9	hSpCas9	negative selection	10217236
3621258	3621281	X	-	28162770	P31FUJ	viability	AAGGCGATTAGGAAACATGAAGG	PRKX	ENSG00000183943	-0.4469270097672262	[144]	[124]	-4	hSpCas9	negative selection	10217237
3713139	3713162	X	+	28162770	P31FUJ	viability	GCGACAGCGCCTCAGGGCTGGGG	PRKX	ENSG00000183943	0.3061478985499412	[222]	[323]	3	hSpCas9	negative selection	10217238
3655180	3655203	X	-	28162770	P31FUJ	viability	GGATGGCCACATTAAGCTCACGG	PRKX	ENSG00000183943	0.7777670372958088	[135]	[273]	8	hSpCas9	negative selection	10217239
3713108	3713131	X	+	28162770	P31FUJ	viability	AAGTCCTGCAGGCTGTACACAGG	PRKX	ENSG00000183943	0.44374920692580566	[355]	[568]	5	hSpCas9	negative selection	10217240
3713097	3713120	X	+	28162770	P31FUJ	viability	CCAGCGTGTCAAAGTCCTGCAGG	PRKX	ENSG00000183943	0.8607971626379127	[275]	[588]	8	hSpCas9	negative selection	10217241
3655357	3655380	X	-	28162770	P31FUJ	viability	CATGCTCATGGAGTACGTGCCGG	PRKX	ENSG00000183943	0.7023813426629425	[238]	[456]	7	hSpCas9	negative selection	10217242
3713196	3713219	X	-	28162770	TF1	viability	GGAGAGCGACTCCCGCAAGGTGG	PRKX	ENSG00000183943	NaN	[NaN]	[151]	1	hSpCas9	negative selection	10386599
3713184	3713207	X	+	28162770	TF1	viability	GGGTCTCCTCCGCCACCTTGCGG	PRKX	ENSG00000183943	NaN	[NaN]	[1077]	1	hSpCas9	negative selection	10386600
3615860	3615883	X	-	28162770	TF1	viability	ATGATGTGAAGCATCATCGGTGG	PRKX	ENSG00000183943	NaN	[NaN]	[0]	1	hSpCas9	negative selection	10386601
3713074	3713097	X	+	28162770	TF1	viability	CCGCACTCACTCACCCACGGTGG	PRKX	ENSG00000183943	NaN	[NaN]	[291]	1	hSpCas9	negative selection	10386602
3621258	3621281	X	-	28162770	TF1	viability	AAGGCGATTAGGAAACATGAAGG	PRKX	ENSG00000183943	NaN	[NaN]	[134]	1	hSpCas9	negative selection	10386603
3713139	3713162	X	+	28162770	TF1	viability	GCGACAGCGCCTCAGGGCTGGGG	PRKX	ENSG00000183943	NaN	[NaN]	[285]	1	hSpCas9	negative selection	10386604
3655180	3655203	X	-	28162770	TF1	viability	GGATGGCCACATTAAGCTCACGG	PRKX	ENSG00000183943	NaN	[NaN]	[203]	1	hSpCas9	negative selection	10386605
3713108	3713131	X	+	28162770	TF1	viability	AAGTCCTGCAGGCTGTACACAGG	PRKX	ENSG00000183943	NaN	[NaN]	[422]	1	hSpCas9	negative selection	10386606
3713097	3713120	X	+	28162770	TF1	viability	CCAGCGTGTCAAAGTCCTGCAGG	PRKX	ENSG00000183943	NaN	[NaN]	[203]	1	hSpCas9	negative selection	10386607
3655357	3655380	X	-	28162770	TF1	viability	CATGCTCATGGAGTACGTGCCGG	PRKX	ENSG00000183943	NaN	[NaN]	[137]	1	hSpCas9	negative selection	10386608
3713196	3713219	X	-	28162770	SKM1	viability	GGAGAGCGACTCCCGCAAGGTGG	PRKX	ENSG00000183943	0.10873563954088072	[31]	[60]	1	hSpCas9	negative selection	10555965
3713184	3713207	X	+	28162770	SKM1	viability	GGGTCTCCTCCGCCACCTTGCGG	PRKX	ENSG00000183943	-0.3604216128061315	[182]	[251]	-3	hSpCas9	negative selection	10555966
3615860	3615883	X	-	28162770	SKM1	viability	ATGATGTGAAGCATCATCGGTGG	PRKX	ENSG00000183943	-0.8220016980220048	[0]	[0]	-6	hSpCas9	negative selection	10555967
3713074	3713097	X	+	28162770	SKM1	viability	CCGCACTCACTCACCCACGGTGG	PRKX	ENSG00000183943	-0.14881201428911406	[36]	[58]	-1	hSpCas9	negative selection	10555968
3621258	3621281	X	-	28162770	SKM1	viability	AAGGCGATTAGGAAACATGAAGG	PRKX	ENSG00000183943	-0.17666657932136764	[38]	[60]	-1	hSpCas9	negative selection	10555969
3713139	3713162	X	+	28162770	SKM1	viability	GCGACAGCGCCTCAGGGCTGGGG	PRKX	ENSG00000183943	0.16794463731407144	[71]	[142]	1	hSpCas9	negative selection	10555970
3655180	3655203	X	-	28162770	SKM1	viability	GGATGGCCACATTAAGCTCACGG	PRKX	ENSG00000183943	0.26546114322833403	[23]	[50]	2	hSpCas9	negative selection	10555971
3713108	3713131	X	+	28162770	SKM1	viability	AAGTCCTGCAGGCTGTACACAGG	PRKX	ENSG00000183943	1.0571439071036088	[55]	[205]	8	hSpCas9	negative selection	10555972
3713097	3713120	X	+	28162770	SKM1	viability	CCAGCGTGTCAAAGTCCTGCAGG	PRKX	ENSG00000183943	-0.7754591120849752	[60]	[62]	-5	hSpCas9	negative selection	10555973
3655357	3655380	X	-	28162770	SKM1	viability	CATGCTCATGGAGTACGTGCCGG	PRKX	ENSG00000183943	0.36644339139110477	[42]	[97]	3	hSpCas9	negative selection	10555974
3713196	3713219	X	-	28162770	SKM1	viability	GGAGAGCGACTCCCGCAAGGTGG	PRKX	ENSG00000183943	0.10873563954088072	[31]	[60]	1	hSpCas9	negative selection	10725331
3713184	3713207	X	+	28162770	SKM1	viability	GGGTCTCCTCCGCCACCTTGCGG	PRKX	ENSG00000183943	-0.3604216128061315	[182]	[251]	-3	hSpCas9	negative selection	10725332
3615860	3615883	X	-	28162770	SKM1	viability	ATGATGTGAAGCATCATCGGTGG	PRKX	ENSG00000183943	-0.8220016980220048	[0]	[0]	-6	hSpCas9	negative selection	10725333
3713074	3713097	X	+	28162770	SKM1	viability	CCGCACTCACTCACCCACGGTGG	PRKX	ENSG00000183943	-0.14881201428911406	[36]	[58]	-1	hSpCas9	negative selection	10725334
3621258	3621281	X	-	28162770	SKM1	viability	AAGGCGATTAGGAAACATGAAGG	PRKX	ENSG00000183943	-0.17666657932136764	[38]	[60]	-1	hSpCas9	negative selection	10725335
3713139	3713162	X	+	28162770	SKM1	viability	GCGACAGCGCCTCAGGGCTGGGG	PRKX	ENSG00000183943	0.16794463731407144	[71]	[142]	1	hSpCas9	negative selection	10725336
3655180	3655203	X	-	28162770	SKM1	viability	GGATGGCCACATTAAGCTCACGG	PRKX	ENSG00000183943	0.26546114322833403	[23]	[50]	2	hSpCas9	negative selection	10725337
3713108	3713131	X	+	28162770	SKM1	viability	AAGTCCTGCAGGCTGTACACAGG	PRKX	ENSG00000183943	1.0571439071036088	[55]	[205]	8	hSpCas9	negative selection	10725338
3713097	3713120	X	+	28162770	SKM1	viability	CCAGCGTGTCAAAGTCCTGCAGG	PRKX	ENSG00000183943	-0.7754591120849752	[60]	[62]	-5	hSpCas9	negative selection	10725339
3655357	3655380	X	-	28162770	SKM1	viability	CATGCTCATGGAGTACGTGCCGG	PRKX	ENSG00000183943	0.36644339139110477	[42]	[97]	3	hSpCas9	negative selection	10725340
3713196	3713219	X	-	28162770	PL21	viability	GGAGAGCGACTCCCGCAAGGTGG	PRKX	ENSG00000183943	1.038388544492708	[65]	[58]	8	hSpCas9	negative selection	10894697
3713184	3713207	X	+	28162770	PL21	viability	GGGTCTCCTCCGCCACCTTGCGG	PRKX	ENSG00000183943	-0.1773581682160883	[568]	[218]	-1	hSpCas9	negative selection	10894698
3615860	3615883	X	-	28162770	PL21	viability	ATGATGTGAAGCATCATCGGTGG	PRKX	ENSG00000183943	1.20013961448932	[0]	[0]	8	hSpCas9	negative selection	10894699
3713074	3713097	X	+	28162770	PL21	viability	CCGCACTCACTCACCCACGGTGG	PRKX	ENSG00000183943	0.4286167982867455	[168]	[98]	4	hSpCas9	negative selection	10894700
3621258	3621281	X	-	28162770	PL21	viability	AAGGCGATTAGGAAACATGAAGG	PRKX	ENSG00000183943	0.12106804349812134	[149]	[70]	1	hSpCas9	negative selection	10894701
3713139	3713162	X	+	28162770	PL21	viability	GCGACAGCGCCTCAGGGCTGGGG	PRKX	ENSG00000183943	-0.7301514136992754	[201]	[52]	-5	hSpCas9	negative selection	10894702
3655180	3655203	X	-	28162770	PL21	viability	GGATGGCCACATTAAGCTCACGG	PRKX	ENSG00000183943	-0.6929451815941681	[103]	[27]	-5	hSpCas9	negative selection	10894703
3713108	3713131	X	+	28162770	PL21	viability	AAGTCCTGCAGGCTGTACACAGG	PRKX	ENSG00000183943	0.5733569380735368	[209]	[135]	5	hSpCas9	negative selection	10894704
3713097	3713120	X	+	28162770	PL21	viability	CCAGCGTGTCAAAGTCCTGCAGG	PRKX	ENSG00000183943	0.5114984676664952	[136]	[84]	4	hSpCas9	negative selection	10894705
3655357	3655380	X	-	28162770	PL21	viability	CATGCTCATGGAGTACGTGCCGG	PRKX	ENSG00000183943	0.011105790099303237	[113]	[49]	0	hSpCas9	negative selection	10894706
3713196	3713219	X	-	28162770	P31FUJ	viability	GGAGAGCGACTCCCGCAAGGTGG	PRKX	ENSG00000183943	0.8987946783688343	[88]	[194]	8	hSpCas9	negative selection	11064063
3713184	3713207	X	+	28162770	P31FUJ	viability	GGGTCTCCTCCGCCACCTTGCGG	PRKX	ENSG00000183943	0.5143113451279104	[764]	[1283]	6	hSpCas9	negative selection	11064064
3615860	3615883	X	-	28162770	P31FUJ	viability	ATGATGTGAAGCATCATCGGTGG	PRKX	ENSG00000183943	-0.23280220441437827	[0]	[0]	-2	hSpCas9	negative selection	11064065
3713074	3713097	X	+	28162770	P31FUJ	viability	CCGCACTCACTCACCCACGGTGG	PRKX	ENSG00000183943	1.0572166425182399	[127]	[312]	9	hSpCas9	negative selection	11064066
3621258	3621281	X	-	28162770	P31FUJ	viability	AAGGCGATTAGGAAACATGAAGG	PRKX	ENSG00000183943	-0.4469270097672262	[144]	[124]	-4	hSpCas9	negative selection	11064067
3713139	3713162	X	+	28162770	P31FUJ	viability	GCGACAGCGCCTCAGGGCTGGGG	PRKX	ENSG00000183943	0.3061478985499412	[222]	[323]	3	hSpCas9	negative selection	11064068
3655180	3655203	X	-	28162770	P31FUJ	viability	GGATGGCCACATTAAGCTCACGG	PRKX	ENSG00000183943	0.7777670372958088	[135]	[273]	8	hSpCas9	negative selection	11064069
3713108	3713131	X	+	28162770	P31FUJ	viability	AAGTCCTGCAGGCTGTACACAGG	PRKX	ENSG00000183943	0.44374920692580566	[355]	[568]	5	hSpCas9	negative selection	11064070
3713097	3713120	X	+	28162770	P31FUJ	viability	CCAGCGTGTCAAAGTCCTGCAGG	PRKX	ENSG00000183943	0.8607971626379127	[275]	[588]	8	hSpCas9	negative selection	11064071
3655357	3655380	X	-	28162770	P31FUJ	viability	CATGCTCATGGAGTACGTGCCGG	PRKX	ENSG00000183943	0.7023813426629425	[238]	[456]	7	hSpCas9	negative selection	11064072
3713196	3713219	X	-	28162770	OCIAML5	viability	GGAGAGCGACTCCCGCAAGGTGG	PRKX	ENSG00000183943	0.15990607080207897	[59]	[120]	1	hSpCas9	negative selection	11233429
3713184	3713207	X	+	28162770	OCIAML5	viability	GGGTCTCCTCCGCCACCTTGCGG	PRKX	ENSG00000183943	1.0053178008561685	[416]	[1510]	8	hSpCas9	negative selection	11233430
3615860	3615883	X	-	28162770	OCIAML5	viability	ATGATGTGAAGCATCATCGGTGG	PRKX	ENSG00000183943	-0.8520665708639967	[0]	[0]	-5	hSpCas9	negative selection	11233431
3713074	3713097	X	+	28162770	OCIAML5	viability	CCGCACTCACTCACCCACGGTGG	PRKX	ENSG00000183943	0.5745589026900587	[92]	[249]	5	hSpCas9	negative selection	11233432
3621258	3621281	X	-	28162770	OCIAML5	viability	AAGGCGATTAGGAAACATGAAGG	PRKX	ENSG00000183943	0.6727749374195884	[97]	[281]	6	hSpCas9	negative selection	11233433
3713139	3713162	X	+	28162770	OCIAML5	viability	GCGACAGCGCCTCAGGGCTGGGG	PRKX	ENSG00000183943	-0.4301096576453627	[155]	[208]	-3	hSpCas9	negative selection	11233434
3655180	3655203	X	-	28162770	OCIAML5	viability	GGATGGCCACATTAAGCTCACGG	PRKX	ENSG00000183943	0.7807244549477744	[88]	[275]	6	hSpCas9	negative selection	11233435
3713108	3713131	X	+	28162770	OCIAML5	viability	AAGTCCTGCAGGCTGTACACAGG	PRKX	ENSG00000183943	0.3178584305783154	[215]	[485]	2	hSpCas9	negative selection	11233436
3713097	3713120	X	+	28162770	OCIAML5	viability	CCAGCGTGTCAAAGTCCTGCAGG	PRKX	ENSG00000183943	0.3641140215391879	[132]	[308]	3	hSpCas9	negative selection	11233437
3655357	3655380	X	-	28162770	OCIAML5	viability	CATGCTCATGGAGTACGTGCCGG	PRKX	ENSG00000183943	0.6846407612499381	[151]	[440]	6	hSpCas9	negative selection	11233438
3713196	3713219	X	-	28162770	EOL1	viability	GGAGAGCGACTCCCGCAAGGTGG	PRKX	ENSG00000183943	1.3777203997361496	[167]	[229]	9	hSpCas9	negative selection	11402795
3713184	3713207	X	+	28162770	EOL1	viability	GGGTCTCCTCCGCCACCTTGCGG	PRKX	ENSG00000183943	1.068395416272041	[886]	[979]	8	hSpCas9	negative selection	11402796
3615860	3615883	X	-	28162770	EOL1	viability	ATGATGTGAAGCATCATCGGTGG	PRKX	ENSG00000183943	0.924547771570535	[0]	[0]	7	hSpCas9	negative selection	11402797
3713074	3713097	X	+	28162770	EOL1	viability	CCGCACTCACTCACCCACGGTGG	PRKX	ENSG00000183943	0.11124848576367355	[303]	[172]	1	hSpCas9	negative selection	11402798
3621258	3621281	X	-	28162770	EOL1	viability	AAGGCGATTAGGAAACATGAAGG	PRKX	ENSG00000183943	-0.45878086798097134	[299]	[114]	-3	hSpCas9	negative selection	11402799
3713139	3713162	X	+	28162770	EOL1	viability	GCGACAGCGCCTCAGGGCTGGGG	PRKX	ENSG00000183943	-0.9716164174449256	[401]	[107]	-6	hSpCas9	negative selection	11402800
3655180	3655203	X	-	28162770	EOL1	viability	GGATGGCCACATTAAGCTCACGG	PRKX	ENSG00000183943	-0.11292693384812846	[116]	[56]	-1	hSpCas9	negative selection	11402801
3713108	3713131	X	+	28162770	EOL1	viability	AAGTCCTGCAGGCTGTACACAGG	PRKX	ENSG00000183943	0.7340858391255276	[282]	[247]	6	hSpCas9	negative selection	11402802
3713097	3713120	X	+	28162770	EOL1	viability	CCAGCGTGTCAAAGTCCTGCAGG	PRKX	ENSG00000183943	0.8985525630375899	[223]	[219]	7	hSpCas9	negative selection	11402803
3655357	3655380	X	-	28162770	EOL1	viability	CATGCTCATGGAGTACGTGCCGG	PRKX	ENSG00000183943	0.17280682472393016	[228]	[135]	1	hSpCas9	negative selection	11402804
3713196	3713219	X	-	28162770	MOLM13	viability	GGAGAGCGACTCCCGCAAGGTGG	PRKX	ENSG00000183943	0.9890552316847657	[130]	[187]	7	hSpCas9	negative selection	11572161
3713184	3713207	X	+	28162770	MOLM13	viability	GGGTCTCCTCCGCCACCTTGCGG	PRKX	ENSG00000183943	0.629935089557305	[815]	[912]	5	hSpCas9	negative selection	11572162
3615860	3615883	X	-	28162770	MOLM13	viability	ATGATGTGAAGCATCATCGGTGG	PRKX	ENSG00000183943	0.4678893815445777	[0]	[0]	3	hSpCas9	negative selection	11572163
3713074	3713097	X	+	28162770	MOLM13	viability	CCGCACTCACTCACCCACGGTGG	PRKX	ENSG00000183943	0.18855316338168432	[266]	[219]	1	hSpCas9	negative selection	11572164
3621258	3621281	X	-	28162770	MOLM13	viability	AAGGCGATTAGGAAACATGAAGG	PRKX	ENSG00000183943	0.6066739724565837	[306]	[337]	4	hSpCas9	negative selection	11572165
3713139	3713162	X	+	28162770	MOLM13	viability	GCGACAGCGCCTCAGGGCTGGGG	PRKX	ENSG00000183943	0.22546525538607098	[277]	[234]	1	hSpCas9	negative selection	11572166
3655180	3655203	X	-	28162770	MOLM13	viability	GGATGGCCACATTAAGCTCACGG	PRKX	ENSG00000183943	-0.5711047500712848	[149]	[72]	-3	hSpCas9	negative selection	11572167
3713108	3713131	X	+	28162770	MOLM13	viability	AAGTCCTGCAGGCTGTACACAGG	PRKX	ENSG00000183943	-0.03593635645117199	[362]	[255]	0	hSpCas9	negative selection	11572168
3713097	3713120	X	+	28162770	MOLM13	viability	CCAGCGTGTCAAAGTCCTGCAGG	PRKX	ENSG00000183943	-0.47682818295423174	[255]	[132]	-3	hSpCas9	negative selection	11572169
3655357	3655380	X	-	28162770	MOLM13	viability	CATGCTCATGGAGTACGTGCCGG	PRKX	ENSG00000183943	0.0888028648618871	[250]	[192]	0	hSpCas9	negative selection	11572170
3713196	3713219	X	-	28162770	HEL	viability	GGAGAGCGACTCCCGCAAGGTGG	PRKX	ENSG00000183943	0.32081073711299457	[99]	[79]	2	hSpCas9	negative selection	11741527
3713184	3713207	X	+	28162770	HEL	viability	GGGTCTCCTCCGCCACCTTGCGG	PRKX	ENSG00000183943	0.7094766398993135	[696]	[729]	6	hSpCas9	negative selection	11741528
3615860	3615883	X	-	28162770	HEL	viability	ATGATGTGAAGCATCATCGGTGG	PRKX	ENSG00000183943	0.6427388320003571	[0]	[0]	5	hSpCas9	negative selection	11741529
3713074	3713097	X	+	28162770	HEL	viability	CCGCACTCACTCACCCACGGTGG	PRKX	ENSG00000183943	0.8201350828738044	[213]	[241]	7	hSpCas9	negative selection	11741530
3621258	3621281	X	-	28162770	HEL	viability	AAGGCGATTAGGAAACATGAAGG	PRKX	ENSG00000183943	-0.5370822055844554	[255]	[112]	-4	hSpCas9	negative selection	11741531
3713139	3713162	X	+	28162770	HEL	viability	GCGACAGCGCCTCAGGGCTGGGG	PRKX	ENSG00000183943	0.93985060671651	[257]	[316]	7	hSpCas9	negative selection	11741532
3655180	3655203	X	-	28162770	HEL	viability	GGATGGCCACATTAAGCTCACGG	PRKX	ENSG00000183943	-0.020226180722072495	[94]	[59]	0	hSpCas9	negative selection	11741533
3713108	3713131	X	+	28162770	HEL	viability	AAGTCCTGCAGGCTGTACACAGG	PRKX	ENSG00000183943	0.7843534374192921	[222]	[245]	6	hSpCas9	negative selection	11741534
3713097	3713120	X	+	28162770	HEL	viability	CCAGCGTGTCAAAGTCCTGCAGG	PRKX	ENSG00000183943	-0.27256400342436177	[214]	[113]	-2	hSpCas9	negative selection	11741535
3655357	3655380	X	-	28162770	HEL	viability	CATGCTCATGGAGTACGTGCCGG	PRKX	ENSG00000183943	-0.16162604745143552	[240]	[137]	-1	hSpCas9	negative selection	11741536
3713196	3713219	X	-	28162770	MV411	viability	GGAGAGCGACTCCCGCAAGGTGG	PRKX	ENSG00000183943	0.7221179964890208	[76]	[106]	6	hSpCas9	negative selection	11910893
3713184	3713207	X	+	28162770	MV411	viability	GGGTCTCCTCCGCCACCTTGCGG	PRKX	ENSG00000183943	0.940075569030077	[541]	[875]	8	hSpCas9	negative selection	11910894
3615860	3615883	X	-	28162770	MV411	viability	ATGATGTGAAGCATCATCGGTGG	PRKX	ENSG00000183943	0.24743755078277552	[0]	[0]	2	hSpCas9	negative selection	11910895
3713074	3713097	X	+	28162770	MV411	viability	CCGCACTCACTCACCCACGGTGG	PRKX	ENSG00000183943	0.3240588323856878	[164]	[173]	3	hSpCas9	negative selection	11910896
3621258	3621281	X	-	28162770	MV411	viability	AAGGCGATTAGGAAACATGAAGG	PRKX	ENSG00000183943	1.347897732561988	[103]	[222]	9	hSpCas9	negative selection	11910897
3713139	3713162	X	+	28162770	MV411	viability	GCGACAGCGCCTCAGGGCTGGGG	PRKX	ENSG00000183943	0.20996284536411258	[194]	[189]	1	hSpCas9	negative selection	11910898
3655180	3655203	X	-	28162770	MV411	viability	GGATGGCCACATTAAGCTCACGG	PRKX	ENSG00000183943	1.2474375507827753	[77]	[155]	9	hSpCas9	negative selection	11910899
3713108	3713131	X	+	28162770	MV411	viability	AAGTCCTGCAGGCTGTACACAGG	PRKX	ENSG00000183943	0.6212523873351063	[212]	[275]	5	hSpCas9	negative selection	11910900
3713097	3713120	X	+	28162770	MV411	viability	CCAGCGTGTCAAAGTCCTGCAGG	PRKX	ENSG00000183943	-0.12668675523001552	[196]	[151]	-1	hSpCas9	negative selection	11910901
3655357	3655380	X	-	28162770	MV411	viability	CATGCTCATGGAGTACGTGCCGG	PRKX	ENSG00000183943	0.40918862077938734	[176]	[197]	3	hSpCas9	negative selection	11910902
3713196	3713219	X	-	28162770	MONOMAC1	viability	GGAGAGCGACTCCCGCAAGGTGG	PRKX	ENSG00000183943	1.1574959132597362	[69]	[178]	8	hSpCas9	negative selection	12080259
3713184	3713207	X	+	28162770	MONOMAC1	viability	GGGTCTCCTCCGCCACCTTGCGG	PRKX	ENSG00000183943	-0.18603784811029644	[391]	[394]	-2	hSpCas9	negative selection	12080260
3615860	3615883	X	-	28162770	MONOMAC1	viability	ATGATGTGAAGCATCATCGGTGG	PRKX	ENSG00000183943	-0.19703684705955382	[0]	[0]	-2	hSpCas9	negative selection	12080261
3713074	3713097	X	+	28162770	MONOMAC1	viability	CCGCACTCACTCACCCACGGTGG	PRKX	ENSG00000183943	0.24858897205271316	[104]	[142]	2	hSpCas9	negative selection	12080262
3621258	3621281	X	-	28162770	MONOMAC1	viability	AAGGCGATTAGGAAACATGAAGG	PRKX	ENSG00000183943	0.16204424624527475	[91]	[117]	1	hSpCas9	negative selection	12080263
3713139	3713162	X	+	28162770	MONOMAC1	viability	GCGACAGCGCCTCAGGGCTGGGG	PRKX	ENSG00000183943	-0.014660104570984683	[140]	[159]	0	hSpCas9	negative selection	12080264
3655180	3655203	X	-	28162770	MONOMAC1	viability	GGATGGCCACATTAAGCTCACGG	PRKX	ENSG00000183943	0.32379531624188684	[68]	[98]	3	hSpCas9	negative selection	12080265
3713108	3713131	X	+	28162770	MONOMAC1	viability	AAGTCCTGCAGGCTGTACACAGG	PRKX	ENSG00000183943	0.08603531201078521	[142]	[173]	0	hSpCas9	negative selection	12080266
3713097	3713120	X	+	28162770	MONOMAC1	viability	CCAGCGTGTCAAAGTCCTGCAGG	PRKX	ENSG00000183943	0.3776573182077753	[93]	[139]	4	hSpCas9	negative selection	12080267
3655357	3655380	X	-	28162770	MONOMAC1	viability	CATGCTCATGGAGTACGTGCCGG	PRKX	ENSG00000183943	0.201047518938093	[106]	[140]	2	hSpCas9	negative selection	12080268
3713196	3713219	X	-	28162770	OCIAML2	viability	GGAGAGCGACTCCCGCAAGGTGG	PRKX	ENSG00000183943	0.9888017933951359	[13]	[153]	8	hSpCas9	negative selection	12249625
3713184	3713207	X	+	28162770	OCIAML2	viability	GGGTCTCCTCCGCCACCTTGCGG	PRKX	ENSG00000183943	0.15208759747441314	[87]	[541]	1	hSpCas9	negative selection	12249626
3615860	3615883	X	-	28162770	OCIAML2	viability	ATGATGTGAAGCATCATCGGTGG	PRKX	ENSG00000183943	-2.4706298252421615	[0]	[0]	-8	hSpCas9	negative selection	12249627
3713074	3713097	X	+	28162770	OCIAML2	viability	CCGCACTCACTCACCCACGGTGG	PRKX	ENSG00000183943	0.4663180042225373	[37]	[290]	4	hSpCas9	negative selection	12249628
3621258	3621281	X	-	28162770	OCIAML2	viability	AAGGCGATTAGGAAACATGAAGG	PRKX	ENSG00000183943	0.27532455215129964	[23]	[160]	2	hSpCas9	negative selection	12249629
3713139	3713162	X	+	28162770	OCIAML2	viability	GCGACAGCGCCTCAGGGCTGGGG	PRKX	ENSG00000183943	0.42051803382061004	[42]	[318]	4	hSpCas9	negative selection	12249630
3655180	3655203	X	-	28162770	OCIAML2	viability	GGATGGCCACATTAAGCTCACGG	PRKX	ENSG00000183943	-0.10605739294630512	[19]	[102]	-1	hSpCas9	negative selection	12249631
3713108	3713131	X	+	28162770	OCIAML2	viability	AAGTCCTGCAGGCTGTACACAGG	PRKX	ENSG00000183943	-0.4311014610555238	[44]	[184]	-3	hSpCas9	negative selection	12249632
3713097	3713120	X	+	28162770	OCIAML2	viability	CCAGCGTGTCAAAGTCCTGCAGG	PRKX	ENSG00000183943	-0.06182427967483212	[28]	[153]	0	hSpCas9	negative selection	12249633
3655357	3655380	X	-	28162770	OCIAML2	viability	CATGCTCATGGAGTACGTGCCGG	PRKX	ENSG00000183943	0.5623852319858017	[26]	[220]	5	hSpCas9	negative selection	12249634
3713196	3713219	X	-	28162770	OCIAML3	viability	GGAGAGCGACTCCCGCAAGGTGG	PRKX	ENSG00000183943	-1.5940076403241634	[27]	[27]	-8	hSpCas9	negative selection	12418991
3713184	3713207	X	+	28162770	OCIAML3	viability	GGGTCTCCTCCGCCACCTTGCGG	PRKX	ENSG00000183943	-0.08080476524588498	[157]	[450]	0	hSpCas9	negative selection	12418992
3615860	3615883	X	-	28162770	OCIAML3	viability	ATGATGTGAAGCATCATCGGTGG	PRKX	ENSG00000183943	-1.594007640324163	[0]	[0]	-8	hSpCas9	negative selection	12418993
3713074	3713097	X	+	28162770	OCIAML3	viability	CCGCACTCACTCACCCACGGTGG	PRKX	ENSG00000183943	-0.31767641187691154	[44]	[108]	-2	hSpCas9	negative selection	12418994
3621258	3621281	X	-	28162770	OCIAML3	viability	AAGGCGATTAGGAAACATGAAGG	PRKX	ENSG00000183943	-0.5565329349055004	[56]	[116]	-4	hSpCas9	negative selection	12418995
3713139	3713162	X	+	28162770	OCIAML3	viability	GCGACAGCGCCTCAGGGCTGGGG	PRKX	ENSG00000183943	0.6796921740669999	[72]	[352]	6	hSpCas9	negative selection	12418996
3655180	3655203	X	-	28162770	OCIAML3	viability	GGATGGCCACATTAAGCTCACGG	PRKX	ENSG00000183943	0.9503128758996471	[17]	[104]	8	hSpCas9	negative selection	12418997
3713108	3713131	X	+	28162770	OCIAML3	viability	AAGTCCTGCAGGCTGTACACAGG	PRKX	ENSG00000183943	0.6334028557789092	[40]	[191]	6	hSpCas9	negative selection	12418998
3713097	3713120	X	+	28162770	OCIAML3	viability	CCAGCGTGTCAAAGTCCTGCAGG	PRKX	ENSG00000183943	-0.27207954543680096	[43]	[109]	-2	hSpCas9	negative selection	12418999
3655357	3655380	X	-	28162770	OCIAML3	viability	CATGCTCATGGAGTACGTGCCGG	PRKX	ENSG00000183943	1.2008020284143273	[32]	[228]	8	hSpCas9	negative selection	12419000