Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:10887
• Symbol:PROKR1
• Description:prokineticin receptor 1

DataSource: http://genomecrispr.dkfz.de/#!/results/PROKR1

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
68645829	68645852	2	-	26472758	Jiyoye	viability	GTCATCCATGAACCCCATGGTGG	PROKR1	ENSG00000169618	-0.49660930323482355	[347]	[185]	-4	hSpCas9	negative selection	127802
68646276	68646299	2	-	26472758	Jiyoye	viability	GGCGATGGCCAGCAGGGCATTGG	PROKR1	ENSG00000169618	-0.5984491676880046	[256]	[127]	-4	hSpCas9	negative selection	127803
68645894	68645917	2	-	26472758	Jiyoye	viability	GAAGTGGCATGGGCTCCATGAGG	PROKR1	ENSG00000169618	-0.09102580729599885	[362]	[256]	0	hSpCas9	negative selection	127804
68645910	68645933	2	-	26472758	Jiyoye	viability	GAAGTTGAATGGGAAGGAAGTGG	PROKR1	ENSG00000169618	-0.5586089031562136	[124]	[63]	-4	hSpCas9	negative selection	127805
68646135	68646158	2	-	26472758	Jiyoye	viability	GGCCACCAGGAAGTCAGAGATGG	PROKR1	ENSG00000169618	1.073174454317936	[74]	[118]	7	hSpCas9	negative selection	127806
68645856	68645879	2	-	26472758	Jiyoye	viability	GAAGCTGGTGGAAGTGTTGGTGG	PROKR1	ENSG00000169618	0.967643320306281	[98]	[145]	6	hSpCas9	negative selection	127807
68646024	68646047	2	-	26472758	Jiyoye	viability	GACCAGCATGATGCCCACCAGGG	PROKR1	ENSG00000169618	0.5137470457039173	[299]	[322]	4	hSpCas9	negative selection	127808
68646226	68646249	2	-	26472758	Jiyoye	viability	GGTAGTTGACAGAGGTGCACAGG	PROKR1	ENSG00000169618	-0.6618662629237778	[106]	[50]	-5	hSpCas9	negative selection	127809
68646247	68646270	2	-	26472758	Jiyoye	viability	CATAGAGAGAGACAGTGCGCAGG	PROKR1	ENSG00000169618	-1.5212713574690926	[235]	[61]	-7	hSpCas9	negative selection	127810
68646160	68646183	2	+	26472758	Jiyoye	viability	TGTCTGCTGCCCCTTTGAGATGG	PROKR1	ENSG00000169618	0.6999571307337195	[79]	[97]	5	hSpCas9	negative selection	127811
68645829	68645852	2	-	26472758	KBM7	viability	GTCATCCATGAACCCCATGGTGG	PROKR1	ENSG00000169618	0.07305311338441034	[1206,941]	[671,397]	0	hSpCas9	negative selection	318920
68646276	68646299	2	-	26472758	KBM7	viability	GGCGATGGCCAGCAGGGCATTGG	PROKR1	ENSG00000169618	0.17245328515196534	[581,609]	[249,378]	1	hSpCas9	negative selection	318921
68645894	68645917	2	-	26472758	KBM7	viability	GAAGTGGCATGGGCTCCATGAGG	PROKR1	ENSG00000169618	-0.3530181325881432	[1574,1077]	[455,503]	-3	hSpCas9	negative selection	318922
68645910	68645933	2	-	26472758	KBM7	viability	GAAGTTGAATGGGAAGGAAGTGG	PROKR1	ENSG00000169618	0.09333293983120089	[403,286]	[224,122]	0	hSpCas9	negative selection	318923
68646135	68646158	2	-	26472758	KBM7	viability	GGCCACCAGGAAGTCAGAGATGG	PROKR1	ENSG00000169618	0.06033703460438866	[477,455]	[181,271]	0	hSpCas9	negative selection	318924
68645856	68645879	2	-	26472758	KBM7	viability	GAAGCTGGTGGAAGTGTTGGTGG	PROKR1	ENSG00000169618	0.24935769810828268	[847,556]	[551,237]	2	hSpCas9	negative selection	318925
68646024	68646047	2	-	26472758	KBM7	viability	GACCAGCATGATGCCCACCAGGG	PROKR1	ENSG00000169618	0.639264246992723	[1678,1772]	[1260,1284]	7	hSpCas9	negative selection	318926
68646226	68646249	2	-	26472758	KBM7	viability	GGTAGTTGACAGAGGTGCACAGG	PROKR1	ENSG00000169618	0.39013447589510336	[352,222]	[235,118]	4	hSpCas9	negative selection	318927
68646247	68646270	2	-	26472758	KBM7	viability	CATAGAGAGAGACAGTGCGCAGG	PROKR1	ENSG00000169618	0.33197613572655393	[529,369]	[332,199]	3	hSpCas9	negative selection	318928
68646160	68646183	2	+	26472758	KBM7	viability	TGTCTGCTGCCCCTTTGAGATGG	PROKR1	ENSG00000169618	0.10568193213061115	[554,395]	[206,264]	1	hSpCas9	negative selection	318929
68645829	68645852	2	-	26472758	Raji	viability	GTCATCCATGAACCCCATGGTGG	PROKR1	ENSG00000169618	0.6309454914306126	[383]	[137]	6	hSpCas9	negative selection	510038
68646276	68646299	2	-	26472758	Raji	viability	GGCGATGGCCAGCAGGGCATTGG	PROKR1	ENSG00000169618	0.1980288998136	[292]	[77]	1	hSpCas9	negative selection	510039
68645894	68645917	2	-	26472758	Raji	viability	GAAGTGGCATGGGCTCCATGAGG	PROKR1	ENSG00000169618	-0.32273592011754504	[608]	[112]	-3	hSpCas9	negative selection	510040
68645910	68645933	2	-	26472758	Raji	viability	GAAGTTGAATGGGAAGGAAGTGG	PROKR1	ENSG00000169618	-0.20340400190856256	[128]	[25]	-2	hSpCas9	negative selection	510041
68646135	68646158	2	-	26472758	Raji	viability	GGCCACCAGGAAGTCAGAGATGG	PROKR1	ENSG00000169618	0.5299547073378507	[190]	[63]	5	hSpCas9	negative selection	510042
68645856	68645879	2	-	26472758	Raji	viability	GAAGCTGGTGGAAGTGTTGGTGG	PROKR1	ENSG00000169618	0.0635884174939148	[300]	[72]	0	hSpCas9	negative selection	510043
68646024	68646047	2	-	26472758	Raji	viability	GACCAGCATGATGCCCACCAGGG	PROKR1	ENSG00000169618	0.5075285665058085	[778]	[256]	5	hSpCas9	negative selection	510044
68646226	68646249	2	-	26472758	Raji	viability	GGTAGTTGACAGAGGTGCACAGG	PROKR1	ENSG00000169618	0.21287666422091345	[144]	[38]	2	hSpCas9	negative selection	510045
68646247	68646270	2	-	26472758	Raji	viability	CATAGAGAGAGACAGTGCGCAGG	PROKR1	ENSG00000169618	0.13486427179570643	[207]	[52]	1	hSpCas9	negative selection	510046
68646160	68646183	2	+	26472758	Raji	viability	TGTCTGCTGCCCCTTTGAGATGG	PROKR1	ENSG00000169618	-0.23246646751102523	[323]	[63]	-2	hSpCas9	negative selection	510047
68645829	68645852	2	-	26472758	K562	viability	GTCATCCATGAACCCCATGGTGG	PROKR1	ENSG00000169618	-0.3774125627701964	[970]	[630]	-3	hSpCas9	negative selection	701156
68646276	68646299	2	-	26472758	K562	viability	GGCGATGGCCAGCAGGGCATTGG	PROKR1	ENSG00000169618	0.6738636507663162	[547]	[737]	5	hSpCas9	negative selection	701157
68645894	68645917	2	-	26472758	K562	viability	GAAGTGGCATGGGCTCCATGAGG	PROKR1	ENSG00000169618	-0.5862378855094342	[826]	[464]	-4	hSpCas9	negative selection	701158
68645910	68645933	2	-	26472758	K562	viability	GAAGTTGAATGGGAAGGAAGTGG	PROKR1	ENSG00000169618	-1.478047296804644	[395]	[119]	-6	hSpCas9	negative selection	701159
68646135	68646158	2	-	26472758	K562	viability	GGCCACCAGGAAGTCAGAGATGG	PROKR1	ENSG00000169618	0.17246888578743197	[369]	[351]	1	hSpCas9	negative selection	701160
68645856	68645879	2	-	26472758	K562	viability	GAAGCTGGTGGAAGTGTTGGTGG	PROKR1	ENSG00000169618	1.1646307017727993	[538]	[1019]	8	hSpCas9	negative selection	701161
68646024	68646047	2	-	26472758	K562	viability	GACCAGCATGATGCCCACCAGGG	PROKR1	ENSG00000169618	0.38732320181167745	[1017]	[1123]	3	hSpCas9	negative selection	701162
68646226	68646249	2	-	26472758	K562	viability	GGTAGTTGACAGAGGTGCACAGG	PROKR1	ENSG00000169618	1.8151673691679022	[169]	[504]	9	hSpCas9	negative selection	701163
68646247	68646270	2	-	26472758	K562	viability	CATAGAGAGAGACAGTGCGCAGG	PROKR1	ENSG00000169618	0.2790913053212264	[369]	[378]	2	hSpCas9	negative selection	701164
68646160	68646183	2	+	26472758	K562	viability	TGTCTGCTGCCCCTTTGAGATGG	PROKR1	ENSG00000169618	-0.2875948931057502	[427]	[295]	-2	hSpCas9	negative selection	701165
68646007	68646030	2	+	26627737	DLD1	viability	GATTGTCATTGGGATGGCCCTGG	PROKR1	ENSG00000169618	-0.6326567460241994	[152]	[21,51,20]	-6	hSpCas9	negative selection	812410
68646079	68646102	2	-	26627737	DLD1	viability	GCAGTTTCTTGTAGCGGACCAGG	PROKR1	ENSG00000169618	0.055000662164768344	[546]	[250,132,150]	0	hSpCas9	negative selection	812411
68646291	68646314	2	-	26627737	DLD1	viability	CACTCACCTGTCAATGGCGATGG	PROKR1	ENSG00000169618	-0.22764813896297076	[811]	[159,351,153]	-2	hSpCas9	negative selection	812412
68654914	68654937	2	+	26627737	DLD1	viability	ATGAAGTGCCAAACAGCCACTGG	PROKR1	ENSG00000169618	-0.2739603589629592	[344]	[73,85,104]	-3	hSpCas9	negative selection	812413
68654979	68655002	2	-	26627737	DLD1	viability	CGGTGGTGAAGTAGGCGGAAGGG	PROKR1	ENSG00000169618	-0.16170059250745372	[1077]	[445,271,199]	-2	hSpCas9	negative selection	812414
68655471	68655494	2	-	26627737	DLD1	viability	CATTGTAAGAAGCCTTCCAGTGG	PROKR1	ENSG00000169618	0.5519140718986673	[215]	[80,118,97]	5	hSpCas9	negative selection	812415
68646007	68646030	2	+	26627737	GBM cells	viability after 5 days	GATTGTCATTGGGATGGCCCTGG	PROKR1	ENSG00000169618	-0.4059407066427352	[41]	[13,19]	-6	hSpCas9	negative selection	894725
68646079	68646102	2	-	26627737	GBM cells	viability after 5 days	GCAGTTTCTTGTAGCGGACCAGG	PROKR1	ENSG00000169618	0.5069316118345074	[268]	[177,231]	7	hSpCas9	negative selection	894726
68646291	68646314	2	-	26627737	GBM cells	viability after 5 days	CACTCACCTGTCAATGGCGATGG	PROKR1	ENSG00000169618	0.15671163235333224	[321]	[192,191]	2	hSpCas9	negative selection	894727
68654914	68654937	2	+	26627737	GBM cells	viability after 5 days	ATGAAGTGCCAAACAGCCACTGG	PROKR1	ENSG00000169618	0.293390051682213	[158]	[93,114]	4	hSpCas9	negative selection	894728
68654979	68655002	2	-	26627737	GBM cells	viability after 5 days	CGGTGGTGAAGTAGGCGGAAGGG	PROKR1	ENSG00000169618	-0.12385101624640871	[510]	[259,242]	-2	hSpCas9	negative selection	894729
68655471	68655494	2	-	26627737	GBM cells	viability after 5 days	CATTGTAAGAAGCCTTCCAGTGG	PROKR1	ENSG00000169618	0.4042881108689791	[235]	[173,160]	6	hSpCas9	negative selection	894730
68646007	68646030	2	+	26627737	GBM cells	viability after 13 days	GATTGTCATTGGGATGGCCCTGG	PROKR1	ENSG00000169618	0.02391689856688739	[41]	[15,28]	0	hSpCas9	negative selection	977040
68646079	68646102	2	-	26627737	GBM cells	viability after 13 days	GCAGTTTCTTGTAGCGGACCAGG	PROKR1	ENSG00000169618	0.3638747573415775	[268]	[253,133]	4	hSpCas9	negative selection	977041
68646291	68646314	2	-	26627737	GBM cells	viability after 13 days	CACTCACCTGTCAATGGCGATGG	PROKR1	ENSG00000169618	0.09603706679961788	[321]	[210,166]	1	hSpCas9	negative selection	977042
68654914	68654937	2	+	26627737	GBM cells	viability after 13 days	ATGAAGTGCCAAACAGCCACTGG	PROKR1	ENSG00000169618	-0.6361728419481052	[158]	[33,72]	-6	hSpCas9	negative selection	977043
68654979	68655002	2	-	26627737	GBM cells	viability after 13 days	CGGTGGTGAAGTAGGCGGAAGGG	PROKR1	ENSG00000169618	0.1026319273015619	[510]	[316,281]	1	hSpCas9	negative selection	977044
68655471	68655494	2	-	26627737	GBM cells	viability after 13 days	CATTGTAAGAAGCCTTCCAGTGG	PROKR1	ENSG00000169618	-0.897097826687209	[235]	[65,70]	-8	hSpCas9	negative selection	977045
68646007	68646030	2	+	26627737	GBM cells	viability after 21 days	GATTGTCATTGGGATGGCCCTGG	PROKR1	ENSG00000169618	0.45600662888215426	[41]	[35,26]	5	hSpCas9	negative selection	1059355
68646079	68646102	2	-	26627737	GBM cells	viability after 21 days	GCAGTTTCTTGTAGCGGACCAGG	PROKR1	ENSG00000169618	0.033737302059308624	[268]	[158,140]	0	hSpCas9	negative selection	1059356
68646291	68646314	2	-	26627737	GBM cells	viability after 21 days	CACTCACCTGTCAATGGCGATGG	PROKR1	ENSG00000169618	-0.1794280728965657	[321]	[154,153]	-2	hSpCas9	negative selection	1059357
68654914	68654937	2	+	26627737	GBM cells	viability after 21 days	ATGAAGTGCCAAACAGCCACTGG	PROKR1	ENSG00000169618	0.5540140956780787	[158]	[130,122]	5	hSpCas9	negative selection	1059358
68654979	68655002	2	-	26627737	GBM cells	viability after 21 days	CGGTGGTGAAGTAGGCGGAAGGG	PROKR1	ENSG00000169618	0.2010693137892845	[510]	[362,278]	2	hSpCas9	negative selection	1059359
68655471	68655494	2	-	26627737	GBM cells	viability after 21 days	CATTGTAAGAAGCCTTCCAGTGG	PROKR1	ENSG00000169618	-0.9346467602631329	[235]	[76,57]	-7	hSpCas9	negative selection	1059360
68646007	68646030	2	+	26627737	RPE1	viability after 9 days	GATTGTCATTGGGATGGCCCTGG	PROKR1	ENSG00000169618	-1.8041331222992907	[325]	[16,44]	-8	hSpCas9	negative selection	1141670
68646079	68646102	2	-	26627737	RPE1	viability after 9 days	GCAGTTTCTTGTAGCGGACCAGG	PROKR1	ENSG00000169618	1.3918702465073511	[635]	[494,557]	7	hSpCas9	negative selection	1141671
68646291	68646314	2	-	26627737	RPE1	viability after 9 days	CACTCACCTGTCAATGGCGATGG	PROKR1	ENSG00000169618	-0.41545889008353765	[1664]	[399,378]	-3	hSpCas9	negative selection	1141672
68654914	68654937	2	+	26627737	RPE1	viability after 9 days	ATGAAGTGCCAAACAGCCACTGG	PROKR1	ENSG00000169618	0.8944677599004724	[174]	[24,200]	6	hSpCas9	negative selection	1141673
68654979	68655002	2	-	26627737	RPE1	viability after 9 days	CGGTGGTGAAGTAGGCGGAAGGG	PROKR1	ENSG00000169618	-0.20249264237766984	[2733]	[635,882]	-1	hSpCas9	negative selection	1141674
68655471	68655494	2	-	26627737	RPE1	viability after 9 days	CATTGTAAGAAGCCTTCCAGTGG	PROKR1	ENSG00000169618	1.6026324385753625	[90]	[96,72]	8	hSpCas9	negative selection	1141675
68646007	68646030	2	+	26627737	RPE1	viability after 12 days	GATTGTCATTGGGATGGCCCTGG	PROKR1	ENSG00000169618	-3.050518298986595	[325]	[12,7]	-9	hSpCas9	negative selection	1223985
68646079	68646102	2	-	26627737	RPE1	viability after 12 days	GCAGTTTCTTGTAGCGGACCAGG	PROKR1	ENSG00000169618	1.2620046305126666	[635]	[436,380]	7	hSpCas9	negative selection	1223986
68646291	68646314	2	-	26627737	RPE1	viability after 12 days	CACTCACCTGTCAATGGCGATGG	PROKR1	ENSG00000169618	0.2780943112759984	[1664]	[420,670]	2	hSpCas9	negative selection	1223987
68654914	68654937	2	+	26627737	RPE1	viability after 12 days	ATGAAGTGCCAAACAGCCACTGG	PROKR1	ENSG00000169618	1.2559308800418114	[174]	[87,137]	7	hSpCas9	negative selection	1223988
68654979	68655002	2	-	26627737	RPE1	viability after 12 days	CGGTGGTGAAGTAGGCGGAAGGG	PROKR1	ENSG00000169618	-0.09898191835636916	[2733]	[696,673]	0	hSpCas9	negative selection	1223989
68655471	68655494	2	-	26627737	RPE1	viability after 12 days	CATTGTAAGAAGCCTTCCAGTGG	PROKR1	ENSG00000169618	2.302402868487164	[90]	[140,98]	9	hSpCas9	negative selection	1223990
68646007	68646030	2	+	26627737	RPE1	viability after 15 days	GATTGTCATTGGGATGGCCCTGG	PROKR1	ENSG00000169618	-2.2776780985986402	[325]	[17,19]	-8	hSpCas9	negative selection	1306300
68646079	68646102	2	-	26627737	RPE1	viability after 15 days	GCAGTTTCTTGTAGCGGACCAGG	PROKR1	ENSG00000169618	1.2630430201863905	[635]	[499,365]	7	hSpCas9	negative selection	1306301
68646291	68646314	2	-	26627737	RPE1	viability after 15 days	CACTCACCTGTCAATGGCGATGG	PROKR1	ENSG00000169618	-0.14047958087017753	[1664]	[213,632]	-1	hSpCas9	negative selection	1306302
68654914	68654937	2	+	26627737	RPE1	viability after 15 days	ATGAAGTGCCAAACAGCCACTGG	PROKR1	ENSG00000169618	0.41052367751724383	[174]	[48,81]	2	hSpCas9	negative selection	1306303
68654979	68655002	2	-	26627737	RPE1	viability after 15 days	CGGTGGTGAAGTAGGCGGAAGGG	PROKR1	ENSG00000169618	-0.11429956749063552	[2733]	[799,631]	0	hSpCas9	negative selection	1306304
68655471	68655494	2	-	26627737	RPE1	viability after 15 days	CATTGTAAGAAGCCTTCCAGTGG	PROKR1	ENSG00000169618	2.676969079996791	[90]	[213,116]	9	hSpCas9	negative selection	1306305
68646007	68646030	2	+	26627737	RPE1	viability after 18 days	GATTGTCATTGGGATGGCCCTGG	PROKR1	ENSG00000169618	-2.8403090799528954	[325]	[5,18]	-9	hSpCas9	negative selection	1388615
68646079	68646102	2	-	26627737	RPE1	viability after 18 days	GCAGTTTCTTGTAGCGGACCAGG	PROKR1	ENSG00000169618	0.9402246375790013	[635]	[280,380]	5	hSpCas9	negative selection	1388616
68646291	68646314	2	-	26627737	RPE1	viability after 18 days	CACTCACCTGTCAATGGCGATGG	PROKR1	ENSG00000169618	0.4934726328741692	[1664]	[430,847]	3	hSpCas9	negative selection	1388617
68654914	68654937	2	+	26627737	RPE1	viability after 18 days	ATGAAGTGCCAAACAGCCACTGG	PROKR1	ENSG00000169618	1.0584597586553128	[174]	[35,164]	6	hSpCas9	negative selection	1388618
68654979	68655002	2	-	26627737	RPE1	viability after 18 days	CGGTGGTGAAGTAGGCGGAAGGG	PROKR1	ENSG00000169618	0.020066811612148072	[2733]	[606,898]	0	hSpCas9	negative selection	1388619
68655471	68655494	2	-	26627737	RPE1	viability after 18 days	CATTGTAAGAAGCCTTCCAGTGG	PROKR1	ENSG00000169618	2.3004542916037516	[90]	[163,74]	9	hSpCas9	negative selection	1388620
68646007	68646030	2	+	26627737	HeLa	viability after 8 days	GATTGTCATTGGGATGGCCCTGG	PROKR1	ENSG00000169618	0.6039087894348847	[37]	[58,0,22]	5	hSpCas9	negative selection	1470930
68646079	68646102	2	-	26627737	HeLa	viability after 8 days	GCAGTTTCTTGTAGCGGACCAGG	PROKR1	ENSG00000169618	0.32141744317933535	[498]	[211,244,338]	3	hSpCas9	negative selection	1470931
68646291	68646314	2	-	26627737	HeLa	viability after 8 days	CACTCACCTGTCAATGGCGATGG	PROKR1	ENSG00000169618	0.2945555332396123	[519]	[180,436,198]	2	hSpCas9	negative selection	1470932
68654914	68654937	2	+	26627737	HeLa	viability after 8 days	ATGAAGTGCCAAACAGCCACTGG	PROKR1	ENSG00000169618	-0.8785101977632618	[638]	[1,313,107]	-7	hSpCas9	negative selection	1470933
68654979	68655002	2	-	26627737	HeLa	viability after 8 days	CGGTGGTGAAGTAGGCGGAAGGG	PROKR1	ENSG00000169618	-0.3326601931758928	[1134]	[768,298,204]	-3	hSpCas9	negative selection	1470934
68655471	68655494	2	-	26627737	HeLa	viability after 8 days	CATTGTAAGAAGCCTTCCAGTGG	PROKR1	ENSG00000169618	0.021203847359260064	[225]	[199,103,22]	0	hSpCas9	negative selection	1470935
68646007	68646030	2	+	26627737	HeLa	viability after 12 days	GATTGTCATTGGGATGGCCCTGG	PROKR1	ENSG00000169618	1.2373926609526626	[37]	[0,8,102]	8	hSpCas9	negative selection	1553245
68646079	68646102	2	-	26627737	HeLa	viability after 12 days	GCAGTTTCTTGTAGCGGACCAGG	PROKR1	ENSG00000169618	0.1212575985658072	[498]	[269,150,260]	1	hSpCas9	negative selection	1553246
68646291	68646314	2	-	26627737	HeLa	viability after 12 days	CACTCACCTGTCAATGGCGATGG	PROKR1	ENSG00000169618	-0.09767238936348405	[519]	[145,180,275]	-1	hSpCas9	negative selection	1553247
68654914	68654937	2	+	26627737	HeLa	viability after 12 days	ATGAAGTGCCAAACAGCCACTGG	PROKR1	ENSG00000169618	-1.9921875683180952	[638]	[15,100,76]	-9	hSpCas9	negative selection	1553248
68654979	68655002	2	-	26627737	HeLa	viability after 12 days	CGGTGGTGAAGTAGGCGGAAGGG	PROKR1	ENSG00000169618	0.12153112601538552	[1134]	[566,429,543]	1	hSpCas9	negative selection	1553249
68655471	68655494	2	-	26627737	HeLa	viability after 12 days	CATTGTAAGAAGCCTTCCAGTGG	PROKR1	ENSG00000169618	-0.1887206866468435	[225]	[107,96,39]	-2	hSpCas9	negative selection	1553250
68646007	68646030	2	+	26627737	HeLa	viability after 15 days	GATTGTCATTGGGATGGCCCTGG	PROKR1	ENSG00000169618	3.3778822470565406	[37]	[55,10,437]	9	hSpCas9	negative selection	1635560
68646079	68646102	2	-	26627737	HeLa	viability after 15 days	GCAGTTTCTTGTAGCGGACCAGG	PROKR1	ENSG00000169618	0.9310125567367757	[498]	[256,369,548]	7	hSpCas9	negative selection	1635561
68646291	68646314	2	-	26627737	HeLa	viability after 15 days	CACTCACCTGTCAATGGCGATGG	PROKR1	ENSG00000169618	0.9315545769061735	[519]	[419,460,323]	7	hSpCas9	negative selection	1635562
68654914	68654937	2	+	26627737	HeLa	viability after 15 days	ATGAAGTGCCAAACAGCCACTGG	PROKR1	ENSG00000169618	-1.8931689357099706	[638]	[0,163,43]	-9	hSpCas9	negative selection	1635563
68654979	68655002	2	-	26627737	HeLa	viability after 15 days	CGGTGGTGAAGTAGGCGGAAGGG	PROKR1	ENSG00000169618	0.6532517791470709	[1134]	[943,388,853]	5	hSpCas9	negative selection	1635564
68655471	68655494	2	-	26627737	HeLa	viability after 15 days	CATTGTAAGAAGCCTTCCAGTGG	PROKR1	ENSG00000169618	-1.643496814793319	[225]	[3,2,85]	-8	hSpCas9	negative selection	1635565
68646007	68646030	2	+	26627737	HeLa	viability after 18 days	GATTGTCATTGGGATGGCCCTGG	PROKR1	ENSG00000169618	3.3430560182920317	[37]	[30,7,437]	9	hSpCas9	negative selection	1717875
68646079	68646102	2	-	26627737	HeLa	viability after 18 days	GCAGTTTCTTGTAGCGGACCAGG	PROKR1	ENSG00000169618	0.9625784401544051	[498]	[178,318,548]	7	hSpCas9	negative selection	1717876
68646291	68646314	2	-	26627737	HeLa	viability after 18 days	CACTCACCTGTCAATGGCGATGG	PROKR1	ENSG00000169618	0.9494770782512629	[519]	[292,379,323]	7	hSpCas9	negative selection	1717877
68654914	68654937	2	+	26627737	HeLa	viability after 18 days	ATGAAGTGCCAAACAGCCACTGG	PROKR1	ENSG00000169618	-1.8545883972487434	[638]	[0,139,43]	-9	hSpCas9	negative selection	1717878
68654979	68655002	2	-	26627737	HeLa	viability after 18 days	CGGTGGTGAAGTAGGCGGAAGGG	PROKR1	ENSG00000169618	0.6726405398933215	[1134]	[646,328,853]	5	hSpCas9	negative selection	1717879
68655471	68655494	2	-	26627737	HeLa	viability after 18 days	CATTGTAAGAAGCCTTCCAGTGG	PROKR1	ENSG00000169618	-1.6202905129823921	[225]	[3,1,85]	-8	hSpCas9	negative selection	1717880
68646007	68646030	2	+	26627737	HCT116	viability after 6 days	GATTGTCATTGGGATGGCCCTGG	PROKR1	ENSG00000169618	-3.9121511605078076	[299]	[6,0]	-9	hSpCas9	negative selection	1800190
68646079	68646102	2	-	26627737	HCT116	viability after 6 days	GCAGTTTCTTGTAGCGGACCAGG	PROKR1	ENSG00000169618	-0.9183835025123144	[729]	[139,16]	-5	hSpCas9	negative selection	1800191
68646291	68646314	2	-	26627737	HCT116	viability after 6 days	CACTCACCTGTCAATGGCGATGG	PROKR1	ENSG00000169618	0.13318123624048062	[889]	[282,81]	0	hSpCas9	negative selection	1800192
68654914	68654937	2	+	26627737	HCT116	viability after 6 days	ATGAAGTGCCAAACAGCCACTGG	PROKR1	ENSG00000169618	1.780754155442452	[340]	[189,180]	8	hSpCas9	negative selection	1800193
68654979	68655002	2	-	26627737	HCT116	viability after 6 days	CGGTGGTGAAGTAGGCGGAAGGG	PROKR1	ENSG00000169618	0.32964477455328	[1934]	[545,291]	1	hSpCas9	negative selection	1800194
68655471	68655494	2	-	26627737	HCT116	viability after 6 days	CATTGTAAGAAGCCTTCCAGTGG	PROKR1	ENSG00000169618	0.5110162558224209	[136]	[11,40]	3	hSpCas9	negative selection	1800195
68646007	68646030	2	+	26627737	HCT116	viability after 8 days	GATTGTCATTGGGATGGCCCTGG	PROKR1	ENSG00000169618	1.4112749529552628	[21]	[36,42,16]	9	hSpCas9	negative selection	1882505
68646079	68646102	2	-	26627737	HCT116	viability after 8 days	GCAGTTTCTTGTAGCGGACCAGG	PROKR1	ENSG00000169618	0.26611123322832403	[418]	[310,282,239]	3	hSpCas9	negative selection	1882506
68646291	68646314	2	-	26627737	HCT116	viability after 8 days	CACTCACCTGTCAATGGCGATGG	PROKR1	ENSG00000169618	-0.009460886967154414	[399]	[221,218,215]	0	hSpCas9	negative selection	1882507
68654914	68654937	2	+	26627737	HCT116	viability after 8 days	ATGAAGTGCCAAACAGCCACTGG	PROKR1	ENSG00000169618	-0.05874818909786905	[213]	[96,99,141]	0	hSpCas9	negative selection	1882508
68654979	68655002	2	-	26627737	HCT116	viability after 8 days	CGGTGGTGAAGTAGGCGGAAGGG	PROKR1	ENSG00000169618	0.5848383496057152	[596]	[503,532,443]	6	hSpCas9	negative selection	1882509
68655471	68655494	2	-	26627737	HCT116	viability after 8 days	CATTGTAAGAAGCCTTCCAGTGG	PROKR1	ENSG00000169618	-0.4956422384541682	[265]	[88,68,152]	-5	hSpCas9	negative selection	1882510
68646007	68646030	2	+	26627737	HCT116	viability after 9 days	GATTGTCATTGGGATGGCCCTGG	PROKR1	ENSG00000169618	-2.2814053857438017	[299]	[30,4]	-9	hSpCas9	negative selection	1964820
68646079	68646102	2	-	26627737	HCT116	viability after 9 days	GCAGTTTCTTGTAGCGGACCAGG	PROKR1	ENSG00000169618	-0.4054998744385915	[729]	[302,23]	-3	hSpCas9	negative selection	1964821
68646291	68646314	2	-	26627737	HCT116	viability after 9 days	CACTCACCTGTCAATGGCGATGG	PROKR1	ENSG00000169618	1.2862061904888296	[889]	[511,632]	8	hSpCas9	negative selection	1964822
68654914	68654937	2	+	26627737	HCT116	viability after 9 days	ATGAAGTGCCAAACAGCCACTGG	PROKR1	ENSG00000169618	1.9482434917770228	[340]	[280,406]	9	hSpCas9	negative selection	1964823
68654979	68655002	2	-	26627737	HCT116	viability after 9 days	CGGTGGTGAAGTAGGCGGAAGGG	PROKR1	ENSG00000169618	-0.03791264864416988	[1934]	[409,576]	0	hSpCas9	negative selection	1964824
68655471	68655494	2	-	26627737	HCT116	viability after 9 days	CATTGTAAGAAGCCTTCCAGTGG	PROKR1	ENSG00000169618	1.4656838620164705	[136]	[114,89]	8	hSpCas9	negative selection	1964825
68646007	68646030	2	+	26627737	HCT116	viability after 12 days	GATTGTCATTGGGATGGCCCTGG	PROKR1	ENSG00000169618	2.144904881137321	[21]	[46,60,45]	9	hSpCas9	negative selection	2047135
68646079	68646102	2	-	26627737	HCT116	viability after 12 days	GCAGTTTCTTGTAGCGGACCAGG	PROKR1	ENSG00000169618	0.23028340635799466	[418]	[325,300,142]	2	hSpCas9	negative selection	2047136
68646291	68646314	2	-	26627737	HCT116	viability after 12 days	CACTCACCTGTCAATGGCGATGG	PROKR1	ENSG00000169618	0.0936402900640198	[399]	[189,226,258]	1	hSpCas9	negative selection	2047137
68654914	68654937	2	+	26627737	HCT116	viability after 12 days	ATGAAGTGCCAAACAGCCACTGG	PROKR1	ENSG00000169618	-0.9013974958944967	[213]	[46,68,65]	-7	hSpCas9	negative selection	2047138
68654979	68655002	2	-	26627737	HCT116	viability after 12 days	CGGTGGTGAAGTAGGCGGAAGGG	PROKR1	ENSG00000169618	0.770034222333664	[596]	[539,673,393]	6	hSpCas9	negative selection	2047139
68655471	68655494	2	-	26627737	HCT116	viability after 12 days	CATTGTAAGAAGCCTTCCAGTGG	PROKR1	ENSG00000169618	-0.5601112706667094	[265]	[58,111,116]	-6	hSpCas9	negative selection	2047140
68646007	68646030	2	+	26627737	HCT116	viability after 15 days	GATTGTCATTGGGATGGCCCTGG	PROKR1	ENSG00000169618	0.8729517732403131	[21]	[18,33,15]	7	hSpCas9	negative selection	2129450
68646079	68646102	2	-	26627737	HCT116	viability after 15 days	GCAGTTTCTTGTAGCGGACCAGG	PROKR1	ENSG00000169618	-0.41603773278538814	[418]	[191,297,53]	-4	hSpCas9	negative selection	2129451
68646291	68646314	2	-	26627737	HCT116	viability after 15 days	CACTCACCTGTCAATGGCGATGG	PROKR1	ENSG00000169618	0.20977130674791616	[399]	[253,226,313]	2	hSpCas9	negative selection	2129452
68654914	68654937	2	+	26627737	HCT116	viability after 15 days	ATGAAGTGCCAAACAGCCACTGG	PROKR1	ENSG00000169618	-1.187361988101749	[213]	[93,37,34]	-8	hSpCas9	negative selection	2129453
68654979	68655002	2	-	26627737	HCT116	viability after 15 days	CGGTGGTGAAGTAGGCGGAAGGG	PROKR1	ENSG00000169618	0.9634063212342239	[596]	[833,710,482]	7	hSpCas9	negative selection	2129454
68655471	68655494	2	-	26627737	HCT116	viability after 15 days	CATTGTAAGAAGCCTTCCAGTGG	PROKR1	ENSG00000169618	-0.21498633287617766	[265]	[145,152,97]	-2	hSpCas9	negative selection	2129455
68646007	68646030	2	+	26627737	HCT116	viability after 18 days	GATTGTCATTGGGATGGCCCTGG	PROKR1	ENSG00000169618	1.6490503822230873	[21]	[16,14,70]	9	hSpCas9	negative selection	2211765
68646079	68646102	2	-	26627737	HCT116	viability after 18 days	GCAGTTTCTTGTAGCGGACCAGG	PROKR1	ENSG00000169618	-0.1904247074777251	[418]	[125,211,192]	-2	hSpCas9	negative selection	2211766
68646291	68646314	2	-	26627737	HCT116	viability after 18 days	CACTCACCTGTCAATGGCGATGG	PROKR1	ENSG00000169618	0.35728796123839973	[399]	[327,181,236]	3	hSpCas9	negative selection	2211767
68654914	68654937	2	+	26627737	HCT116	viability after 18 days	ATGAAGTGCCAAACAGCCACTGG	PROKR1	ENSG00000169618	-0.34037616220712485	[213]	[98,92,50]	-3	hSpCas9	negative selection	2211768
68654979	68655002	2	-	26627737	HCT116	viability after 18 days	CGGTGGTGAAGTAGGCGGAAGGG	PROKR1	ENSG00000169618	1.1616913057709282	[596]	[624,774,522]	8	hSpCas9	negative selection	2211769
68655471	68655494	2	-	26627737	HCT116	viability after 18 days	CATTGTAAGAAGCCTTCCAGTGG	PROKR1	ENSG00000169618	-0.5703203577806029	[265]	[43,93,122]	-5	hSpCas9	negative selection	2211770
68645680	68645703	2	+	25494202	A375	resistance to PLX-4720 (puromycin)	ATACCATACCCCAAAGATGCTGG	PROKR1	ENSG00000169618	1.8600132300324712	[99,117]	[71,103]	6	dCas9-VP64	positive selection	2464791
68645705	68645728	2	+	25494202	A375	resistance to PLX-4720 (puromycin)	GAGACATTCTGACTCATTAAGGG	PROKR1	ENSG00000169618	0.8978059912190537	[323,218]	[92,129]	3	dCas9-VP64	positive selection	2464792
68645650	68645673	2	+	25494202	A375	resistance to PLX-4720 (puromycin)	TGTCTTTCAAAGGTTTAGAATGG	PROKR1	ENSG00000169618	0.7380982582867293	[77,65]	[19,32]	3	dCas9-VP64	positive selection	2464793
68645680	68645703	2	+	25494202	A375	resistance to PLX-4720 (zeocin)	ATACCATACCCCAAAGATGCTGG	PROKR1	ENSG00000169618	0.6116919603951507	[90,301]	[61,129]	4	dCas9-VP64	positive selection	2560046
68645705	68645728	2	+	25494202	A375	resistance to PLX-4720 (zeocin)	GAGACATTCTGACTCATTAAGGG	PROKR1	ENSG00000169618	1.6358297213546007	[80,192]	[42,225]	8	dCas9-VP64	positive selection	2560047
68645650	68645673	2	+	25494202	A375	resistance to PLX-4720 (zeocin)	TGTCTTTCAAAGGTTTAGAATGG	PROKR1	ENSG00000169618	0.708101675058856	[131,265]	[64,143]	5	dCas9-VP64	positive selection	2560048
68645832	68645855	2	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	ATTGTCATCCATGAACCCCATGG	PROKR1	ENSG00000169618	0.06325301941165895	[6,6]	[5,5]	1	hSpCas9	positive selection	3013814
68654899	68654922	2	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CACTTCATCCGTGGTCTCAGCGG	PROKR1	ENSG00000169618	-0.1093884477900131	[4,4]	[3,3]	-1	hSpCas9	positive selection	3013815
68646169	68646192	2	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CATAGTAGTCCATCTCAAAGGGG	PROKR1	ENSG00000169618	0.5707330187987687	[3,3]	[3,5]	9	hSpCas9	positive selection	3013816
68646134	68646157	2	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GGCCATCTCTGACTTCCTGGTGG	PROKR1	ENSG00000169618	0.11302543719966829	[4,4]	[4,3]	2	hSpCas9	positive selection	3013817
68645832	68645855	2	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	ATTGTCATCCATGAACCCCATGG	PROKR1	ENSG00000169618	0.4032800304174088	[6,6]	[5,5]	7	hSpCas9	positive selection	3081672
68654899	68654922	2	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CACTTCATCCGTGGTCTCAGCGG	PROKR1	ENSG00000169618	0.24801018302290873	[4,4]	[2,4]	4	hSpCas9	positive selection	3081673
68646169	68646192	2	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CATAGTAGTCCATCTCAAAGGGG	PROKR1	ENSG00000169618	0.4715961029252051	[3,3]	[3,2]	7	hSpCas9	positive selection	3081674
68646134	68646157	2	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GGCCATCTCTGACTTCCTGGTGG	PROKR1	ENSG00000169618	-0.012124037681909394	[4,4]	[4,2]	0	hSpCas9	positive selection	3081675
68646291	68646314		-	24336571	A375	resistance to PLX after 7 days	CACTCACCTGTCAATGGCGATGG	PROKR1	ENSG00000169618	-0.15184740151587092	[10,11]	[10,9]	-5	hSpCas9	positive selection	3137936
68645938	68645961		+	24336571	A375	resistance to PLX after 7 days	CAGCGACTATGATATGCCTTTGG	PROKR1	ENSG00000169618	-0.13076977736991344	[13,13]	[14,10]	-4	hSpCas9	positive selection	3137937
68655108	68655131		+	24336571	A375	resistance to PLX after 7 days	CATAGAATTCGTGGGCCCCGTGG	PROKR1	ENSG00000169618	-0.024821166388455308	[11,11]	[11,11]	0	hSpCas9	positive selection	3137938
68654945	68654968		-	24336571	A375	resistance to PLX after 7 days	GATGGACACCGTCCACACCAAGG	PROKR1	ENSG00000169618	-0.3741551258763175	[11,13]	[8,10]	-9	hSpCas9	positive selection	3137939
68655263	68655286		+	24336571	A375	resistance to PLX after 7 days	TCACCGCCTACGTGCTATGCTGG	PROKR1	ENSG00000169618	-0.21204747609245933	[90,79]	[76,69]	-6	hSpCas9	positive selection	3137941
68646291	68646314		-	24336571	A375	resistance to PLX after 14 days	CACTCACCTGTCAATGGCGATGG	PROKR1	ENSG00000169618	-0.12738395545272585	[8,10]	[4,2]	-1	hSpCas9	positive selection	3195729
68645938	68645961		+	24336571	A375	resistance to PLX after 14 days	CAGCGACTATGATATGCCTTTGG	PROKR1	ENSG00000169618	-0.6727890217645115	[11,14]	[3,2]	-7	hSpCas9	positive selection	3195730
68655108	68655131		+	24336571	A375	resistance to PLX after 14 days	CATAGAATTCGTGGGCCCCGTGG	PROKR1	ENSG00000169618	-0.04299164943172856	[11,10]	[4,4]	0	hSpCas9	positive selection	3195731
68654945	68654968		-	24336571	A375	resistance to PLX after 14 days	GATGGACACCGTCCACACCAAGG	PROKR1	ENSG00000169618	-0.8114084268695726	[12,11]	[3,1]	-8	hSpCas9	positive selection	3195732
68655263	68655286		+	24336571	A375	resistance to PLX after 14 days	TCACCGCCTACGTGCTATGCTGG	PROKR1	ENSG00000169618	-1.0316555522373352	[71,84]	[18,15]	-9	hSpCas9	positive selection	3195734
68646291	68646314		-	24336571	A375	viability after 7 days	CACTCACCTGTCAATGGCGATGG	PROKR1	ENSG00000169618	0.1769713360728006	[10]	[10,11]	2	hSpCas9	negative selection	3253522
68645938	68645961		+	24336571	A375	viability after 7 days	CAGCGACTATGATATGCCTTTGG	PROKR1	ENSG00000169618	0.5287033063248942	[9]	[13,13]	7	hSpCas9	negative selection	3253523
68655108	68655131		+	24336571	A375	viability after 7 days	CATAGAATTCGTGGGCCCCGTGG	PROKR1	ENSG00000169618	0.5908265351025962	[7]	[11,11]	8	hSpCas9	negative selection	3253524
68654945	68654968		-	24336571	A375	viability after 7 days	GATGGACACCGTCCACACCAAGG	PROKR1	ENSG00000169618	0.14777312239260512	[11]	[11,13]	2	hSpCas9	negative selection	3253525
68655263	68655286		+	24336571	A375	viability after 7 days	TCACCGCCTACGTGCTATGCTGG	PROKR1	ENSG00000169618	0.5714077699916431	[59]	[90,79]	8	hSpCas9	negative selection	3253527
68646291	68646314		-	24336571	A375	viability after 14 days	CACTCACCTGTCAATGGCGATGG	PROKR1	ENSG00000169618	-0.04972140273849501	[10]	[8,10]	0	hSpCas9	negative selection	3311315
68645938	68645961		+	24336571	A375	viability after 14 days	CAGCGACTATGATATGCCTTTGG	PROKR1	ENSG00000169618	0.43346069108421703	[9]	[11,14]	5	hSpCas9	negative selection	3311316
68655108	68655131		+	24336571	A375	viability after 14 days	CATAGAATTCGTGGGCCCCGTGG	PROKR1	ENSG00000169618	0.46723235837179367	[7]	[11,10]	6	hSpCas9	negative selection	3311317
68654945	68654968		-	24336571	A375	viability after 14 days	GATGGACACCGTCCACACCAAGG	PROKR1	ENSG00000169618	0.10973102362562798	[11]	[12,11]	1	hSpCas9	negative selection	3311318
68655263	68655286		+	24336571	A375	viability after 14 days	TCACCGCCTACGTGCTATGCTGG	PROKR1	ENSG00000169618	0.46366468512368186	[59]	[71,84]	6	hSpCas9	negative selection	3311320
68645985	68646008	2	-	27383988	293T	resistance to West Nile virus (flavivirus)	CTTGGCAGCAAAGAACGTCCTGG	PROKR1	ENSG00000169618	-0.2184072195205627	[177,177]	[0,0]	-1	hSpCas9	positive selection	3387606
68655269	68655292	2	-	27383988	293T	resistance to West Nile virus (flavivirus)	GGGCGCCCAGCATAGCACGTAGG	PROKR1	ENSG00000169618	0.7181674003378036	[92,92]	[0,0]	3	hSpCas9	positive selection	3387607
68654945	68654968	2	-	27383988	293T	resistance to West Nile virus (flavivirus)	GATGGACACCGTCCACACCAAGG	PROKR1	ENSG00000169618	-0.714217342504937	[250,250]	[0,0]	-5	hSpCas9	positive selection	3387608
68645832	68645855	2	-	26780180	HT29	viability (Avana library 4 designs)	ATTGTCATCCATGAACCCCATGG	PROKR1	ENSG00000169618	-0.0926112705687293	[]	[]	-1	hSpCas9	negative selection	3452009
68654899	68654922	2	-	26780180	HT29	viability (Avana library 4 designs)	CACTTCATCCGTGGTCTCAGCGG	PROKR1	ENSG00000169618	0.306945677397299	[]	[]	1	hSpCas9	negative selection	3452010
68646169	68646192	2	-	26780180	HT29	viability (Avana library 4 designs)	CATAGTAGTCCATCTCAAAGGGG	PROKR1	ENSG00000169618	2.13080508586387	[]	[]	7	hSpCas9	negative selection	3452011
68646133	68646156	2	+	26780180	HT29	viability (Avana library 4 designs)	GGCCATCTCTGACTTCCTGGTGG	PROKR1	ENSG00000169618	0.388516210584262	[]	[]	1	hSpCas9	negative selection	3452012
68646133	68646156	2	+	26780180	A375	viability (Avana lentiCRISPRv2)	GGCCATCTCTGACTTCCTGGTGG	PROKR1	ENSG00000169618	-0.688553928375542	[]	[]	-1	hSpCas9	negative selection	3548174
68646169	68646192	2	-	26780180	A375	viability (Avana lentiCRISPRv2)	CATAGTAGTCCATCTCAAAGGGG	PROKR1	ENSG00000169618	-5.31374336570084	[]	[]	-5	hSpCas9	negative selection	3548175
68645832	68645855	2	-	26780180	A375	viability (Avana lentiCRISPRv2)	ATTGTCATCCATGAACCCCATGG	PROKR1	ENSG00000169618	-1.62331857133904	[]	[]	-2	hSpCas9	negative selection	3548176
68654899	68654922	2	-	26780180	A375	viability (Avana lentiCRISPRv2)	CACTTCATCCGTGGTCTCAGCGG	PROKR1	ENSG00000169618	0.973799708432997	[]	[]	1	hSpCas9	negative selection	3548177
68646085	68646108	2	-	26780180	A375	viability (Avana lentiCRISPRv2)	GGTTGCGCAGTTTCTTGTAGCGG	PROKR1	ENSG00000169618	2.26918824650324	[]	[]	3	hSpCas9	negative selection	3548178
68654891	68654914	2	+	26780180	A375	viability (Avana lentiCRISPRv2)	TTGTCCATCCGCTGAGACCACGG	PROKR1	ENSG00000169618	3.43555768809436	[]	[]	5	hSpCas9	negative selection	3548179
68646133	68646156	2	+	26780180	A375	viability (Avana lentiGuide)	GGCCATCTCTGACTTCCTGGTGG	PROKR1	ENSG00000169618	1.94190053681022	[]	[]	2	hSpCas9	negative selection	3656833
68646169	68646192	2	-	26780180	A375	viability (Avana lentiGuide)	CATAGTAGTCCATCTCAAAGGGG	PROKR1	ENSG00000169618	0.631475822022332	[]	[]	0	hSpCas9	negative selection	3656834
68645832	68645855	2	-	26780180	A375	viability (Avana lentiGuide)	ATTGTCATCCATGAACCCCATGG	PROKR1	ENSG00000169618	0.320158612243104	[]	[]	0	hSpCas9	negative selection	3656835
68654899	68654922	2	-	26780180	A375	viability (Avana lentiGuide)	CACTTCATCCGTGGTCTCAGCGG	PROKR1	ENSG00000169618	1.01962919958757	[]	[]	1	hSpCas9	negative selection	3656836
68646085	68646108	2	-	26780180	A375	viability (Avana lentiGuide)	GGTTGCGCAGTTTCTTGTAGCGG	PROKR1	ENSG00000169618	0.0539597982114084	[]	[]	0	hSpCas9	negative selection	3656837
68654891	68654914	2	+	26780180	A375	viability (Avana lentiGuide)	TTGTCCATCCGCTGAGACCACGG	PROKR1	ENSG00000169618	-0.219969798214903	[]	[]	0	hSpCas9	negative selection	3656838
68646133	68646156	2	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGCCATCTCTGACTTCCTGGTGG	PROKR1	ENSG00000169618	-0.1325464475196353	[5]	[5,4]	-2	hSpCas9	positive selection	3765440
68646169	68646192	2	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CATAGTAGTCCATCTCAAAGGGG	PROKR1	ENSG00000169618	-0.5497797016667607	[5]	[3,2]	-7	hSpCas9	positive selection	3765441
68645832	68645855	2	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ATTGTCATCCATGAACCCCATGG	PROKR1	ENSG00000169618	-0.14768044584166956	[7]	[6,5]	-2	hSpCas9	positive selection	3765442
68654899	68654922	2	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CACTTCATCCGTGGTCTCAGCGG	PROKR1	ENSG00000169618	0.14811444562192194	[5]	[6,6]	4	hSpCas9	positive selection	3765443
68646085	68646108	2	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGTTGCGCAGTTTCTTGTAGCGG	PROKR1	ENSG00000169618	0.2713369295078244	[5]	[7,6]	7	hSpCas9	positive selection	3765444
68654891	68654914	2	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TTGTCCATCCGCTGAGACCACGG	PROKR1	ENSG00000169618	0.14685482620164436	[6]	[6,7]	4	hSpCas9	positive selection	3765445
68646133	68646156	2	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGCCATCTCTGACTTCCTGGTGG	PROKR1	ENSG00000169618	0.12344344849060218	[6]	[6,5]	3	hSpCas9	positive selection	3874047
68646169	68646192	2	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CATAGTAGTCCATCTCAAAGGGG	PROKR1	ENSG00000169618	-0.38811834005062185	[4]	[2,3]	-5	hSpCas9	positive selection	3874048
68645832	68645855	2	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ATTGTCATCCATGAACCCCATGG	PROKR1	ENSG00000169618	0.16621484356752692	[7]	[8,6]	4	hSpCas9	positive selection	3874049
68654899	68654922	2	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CACTTCATCCGTGGTCTCAGCGG	PROKR1	ENSG00000169618	-0.0014320612721877013	[6]	[4,5]	0	hSpCas9	positive selection	3874050
68646085	68646108	2	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGTTGCGCAGTTTCTTGTAGCGG	PROKR1	ENSG00000169618	0.2394234725978831	[7]	[7,6]	6	hSpCas9	positive selection	3874051
68654891	68654914	2	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TTGTCCATCCGCTGAGACCACGG	PROKR1	ENSG00000169618	0.2991122260783345	[7]	[7,7]	8	hSpCas9	positive selection	3874052
68645938	68645961	2	+	26780180	A375	viability	CAGCGACTATGATATGCCTTTGG	PROKR1	ENSG00000169618	1.15489472384138	[]	[]	6	hSpCas9	negative selection	3984514
68655108	68655131	2	+	26780180	A375	viability	CATAGAATTCGTGGGCCCCGTGG	PROKR1	ENSG00000169618	0.974651541600823	[]	[]	4	hSpCas9	negative selection	3984515
68645985	68646008	2	-	26780180	A375	viability	CTTGGCAGCAAAGAACGTCCTGG	PROKR1	ENSG00000169618	1.3238911923007	[]	[]	7	hSpCas9	negative selection	3984516
68654945	68654968	2	-	26780180	A375	viability	GATGGACACCGTCCACACCAAGG	PROKR1	ENSG00000169618	0.613677344319326	[]	[]	2	hSpCas9	negative selection	3984517
68655269	68655292	2	-	26780180	A375	viability	GGGCGCCCAGCATAGCACGTAGG	PROKR1	ENSG00000169618	0.91193761005491	[]	[]	4	hSpCas9	negative selection	3984518
68655305	68655328	2	-	26780180	A375	viability	GGGGAAGAAGTCGCGCACGATGG	PROKR1	ENSG00000169618	0.71573745066812	[]	[]	2	hSpCas9	negative selection	3984519
68645938	68645961	2	+	26780180	HT29	viability (GeCKOv2 library)	CAGCGACTATGATATGCCTTTGG	PROKR1	ENSG00000169618	0.856827596716843	[]	[]	3	hSpCas9	negative selection	4092480
68655108	68655131	2	+	26780180	HT29	viability (GeCKOv2 library)	CATAGAATTCGTGGGCCCCGTGG	PROKR1	ENSG00000169618	0.712288071879413	[]	[]	2	hSpCas9	negative selection	4092481
68645985	68646008	2	-	26780180	HT29	viability (GeCKOv2 library)	CTTGGCAGCAAAGAACGTCCTGG	PROKR1	ENSG00000169618	0.990134431487991	[]	[]	4	hSpCas9	negative selection	4092482
68654945	68654968	2	-	26780180	HT29	viability (GeCKOv2 library)	GATGGACACCGTCCACACCAAGG	PROKR1	ENSG00000169618	0.52753866604025	[]	[]	1	hSpCas9	negative selection	4092483
68655269	68655292	2	-	26780180	HT29	viability (GeCKOv2 library)	GGGCGCCCAGCATAGCACGTAGG	PROKR1	ENSG00000169618	0.919421307107874	[]	[]	4	hSpCas9	negative selection	4092484
68655305	68655328	2	-	26780180	HT29	viability (GeCKOv2 library)	GGGGAAGAAGTCGCGCACGATGG	PROKR1	ENSG00000169618	0.392505657644118	[]	[]	1	hSpCas9	negative selection	4092485
68646291	68646314	2	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CACTCACCTGTCAATGGCGATGG	PROKR1	ENSG00000169618	-0.1840603434080933	[3]	[1,1]	-4	hSpCas9	positive selection	4163108
68645938	68645961	2	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CAGCGACTATGATATGCCTTTGG	PROKR1	ENSG00000169618	-0.13842980636171098	[3]	[2,1]	-3	hSpCas9	positive selection	4163109
68655108	68655131	2	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CATAGAATTCGTGGGCCCCGTGG	PROKR1	ENSG00000169618	-0.11429796015352973	[3]	[1,2]	-3	hSpCas9	positive selection	4163110
68654945	68654968	2	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GATGGACACCGTCCACACCAAGG	PROKR1	ENSG00000169618	-0.17176116120519005	[3]	[2,1]	-4	hSpCas9	positive selection	4163111
68655263	68655286	2	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TCACCGCCTACGTGCTATGCTGG	PROKR1	ENSG00000169618	0.06473610498214577	[5]	[4,4]	1	hSpCas9	positive selection	4163113
68646291	68646314	2	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CACTCACCTGTCAATGGCGATGG	PROKR1	ENSG00000169618	0.3749539950123792	[2]	[4,1,0,0]	3	hSpCas9	positive selection	4227130
68645938	68645961	2	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CAGCGACTATGATATGCCTTTGG	PROKR1	ENSG00000169618	0.35345011409527394	[2]	[1,1,1,0]	2	hSpCas9	positive selection	4227131
68655108	68655131	2	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CATAGAATTCGTGGGCCCCGTGG	PROKR1	ENSG00000169618	-0.7631133288717206	[3]	[0,0,0,0]	-9	hSpCas9	positive selection	4227132
68654945	68654968	2	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GATGGACACCGTCCACACCAAGG	PROKR1	ENSG00000169618	-0.1554117169153934	[3]	[1,2,0,0]	-2	hSpCas9	positive selection	4227133
68655263	68655286	2	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TCACCGCCTACGTGCTATGCTGG	PROKR1	ENSG00000169618	0.18131516979536333	[5]	[4,4,3,0]	1	hSpCas9	positive selection	4227135
68655305	68655328	2	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GGGGAAGAAGTCGCGCACGATGG	PROKR1	ENSG00000169618	0.03649100500592817	[1]	[1,0]	0	hSpCas9	positive selection	4292305
68655108	68655131	2	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CATAGAATTCGTGGGCCCCGTGG	PROKR1	ENSG00000169618	0.352475305390469	[2]	[2,2]	7	hSpCas9	positive selection	4292306
68645938	68645961	2	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CAGCGACTATGATATGCCTTTGG	PROKR1	ENSG00000169618	-0.13471640803936685	[2]	[2,0]	-3	hSpCas9	positive selection	4292307
68645985	68646008	2	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CTTGGCAGCAAAGAACGTCCTGG	PROKR1	ENSG00000169618	0.25732610185446664	[2]	[2,2]	5	hSpCas9	positive selection	4356564
68655269	68655292	2	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GGGCGCCCAGCATAGCACGTAGG	PROKR1	ENSG00000169618	0.305431331416144	[1]	[3,0]	6	hSpCas9	positive selection	4356565
68654945	68654968	2	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GATGGACACCGTCCACACCAAGG	PROKR1	ENSG00000169618	0.3854506247777553	[3]	[3,3]	7	hSpCas9	positive selection	4356566
68645979	68646001	2	-	27760321	OCIAML3	viability	GCAAAGAACGTCCTGGAATTGG	PROKR1	ENSG00000169618	0.3535477617816542	[386,331]	[322,403]	4	hSpCas9	negative selection	4430795
68646079	68646101	2	-	27760321	OCIAML3	viability	CAGTTTCTTGTAGCGGACCAGG	PROKR1	ENSG00000169618	0.5165841128095908	[720,631]	[631,915]	6	hSpCas9	negative selection	4430796
68654895	68654917	2	-	27760321	OCIAML3	viability	CATCCGTGGTCTCAGCGGATGG	PROKR1	ENSG00000169618	-0.12371934771045107	[682,618]	[459,475]	-1	hSpCas9	negative selection	4430797
68654908	68654930	2	-	27760321	OCIAML3	viability	CTGTTTGGCACTTCATCCGTGG	PROKR1	ENSG00000169618	0.5489301113191933	[1055,897]	[946,1331]	6	hSpCas9	negative selection	4430798
68655109	68655131	2	+	27760321	OCIAML3	viability	ATAGAATTCGTGGGCCCCGTGG	PROKR1	ENSG00000169618	0.36403860986768916	[705,518]	[523,723]	4	hSpCas9	negative selection	4430799
68645979	68646001	2	-	27760321	OCIAML2	viability	GCAAAGAACGTCCTGGAATTGG	PROKR1	ENSG00000169618	0.7675256734048086	[386,331]	[468,525]	9	hSpCas9	negative selection	4514258
68646079	68646101	2	-	27760321	OCIAML2	viability	CAGTTTCTTGTAGCGGACCAGG	PROKR1	ENSG00000169618	0.36758555007018245	[720,631]	[619,815]	5	hSpCas9	negative selection	4514259
68654895	68654917	2	-	27760321	OCIAML2	viability	CATCCGTGGTCTCAGCGGATGG	PROKR1	ENSG00000169618	0.2569982904058148	[682,618]	[608,654]	3	hSpCas9	negative selection	4514260
68654908	68654930	2	-	27760321	OCIAML2	viability	CTGTTTGGCACTTCATCCGTGG	PROKR1	ENSG00000169618	0.7520236794692157	[1055,897]	[1194,1499]	8	hSpCas9	negative selection	4514261
68655109	68655131	2	+	27760321	OCIAML2	viability	ATAGAATTCGTGGGCCCCGTGG	PROKR1	ENSG00000169618	0.40744376911051167	[705,518]	[572,753]	5	hSpCas9	negative selection	4514262
68645979	68646001	2	-	27760321	MV411	viability	GCAAAGAACGTCCTGGAATTGG	PROKR1	ENSG00000169618	0.6829746728287562	[386,331]	[531,150]	5	hSpCas9	negative selection	4597721
68646079	68646101	2	-	27760321	MV411	viability	CAGTTTCTTGTAGCGGACCAGG	PROKR1	ENSG00000169618	0.8234346946261991	[720,631]	[456,1285]	6	hSpCas9	negative selection	4597722
68654895	68654917	2	-	27760321	MV411	viability	CATCCGTGGTCTCAGCGGATGG	PROKR1	ENSG00000169618	0.9746390028070898	[682,618]	[584,1231]	7	hSpCas9	negative selection	4597723
68654908	68654930	2	-	27760321	MV411	viability	CTGTTTGGCACTTCATCCGTGG	PROKR1	ENSG00000169618	0.5573233976659326	[1055,897]	[646,1393]	4	hSpCas9	negative selection	4597724
68655109	68655131	2	+	27760321	MV411	viability	ATAGAATTCGTGGGCCCCGTGG	PROKR1	ENSG00000169618	-0.09194016954900464	[705,518]	[288,505]	0	hSpCas9	negative selection	4597725
68645979	68646001	2	-	27760321	HL60	viability	GCAAAGAACGTCCTGGAATTGG	PROKR1	ENSG00000169618	-0.012762391639508708	[386,331]	[263,317]	0	hSpCas9	negative selection	4681184
68646079	68646101	2	-	27760321	HL60	viability	CAGTTTCTTGTAGCGGACCAGG	PROKR1	ENSG00000169618	0.27965510539222094	[720,631]	[715,619]	3	hSpCas9	negative selection	4681185
68654895	68654917	2	-	27760321	HL60	viability	CATCCGTGGTCTCAGCGGATGG	PROKR1	ENSG00000169618	-0.08635301537584245	[682,618]	[500,499]	-1	hSpCas9	negative selection	4681186
68654908	68654930	2	-	27760321	HL60	viability	CTGTTTGGCACTTCATCCGTGG	PROKR1	ENSG00000169618	-0.019649657661926945	[1055,897]	[739,831]	0	hSpCas9	negative selection	4681187
68655109	68655131	2	+	27760321	HL60	viability	ATAGAATTCGTGGGCCCCGTGG	PROKR1	ENSG00000169618	-0.2684232815738151	[705,518]	[462,356]	-3	hSpCas9	negative selection	4681188
68645979	68646001	2	-	27760321	HT1080	viability	GCAAAGAACGTCCTGGAATTGG	PROKR1	ENSG00000169618	0.25732408365224463	[331,258]	[165,112]	1	hSpCas9	negative selection	4764647
68646079	68646101	2	-	27760321	HT1080	viability	CAGTTTCTTGTAGCGGACCAGG	PROKR1	ENSG00000169618	0.1877286977286492	[631,492]	[185,330]	0	hSpCas9	negative selection	4764648
68654895	68654917	2	-	27760321	HT1080	viability	CATCCGTGGTCTCAGCGGATGG	PROKR1	ENSG00000169618	1.1616917972019993	[618,482]	[386,604]	6	hSpCas9	negative selection	4764649
68654908	68654930	2	-	27760321	HT1080	viability	CTGTTTGGCACTTCATCCGTGG	PROKR1	ENSG00000169618	1.3062838042374838	[897,700]	[611,979]	7	hSpCas9	negative selection	4764650
68655109	68655131	2	+	27760321	HT1080	viability	ATAGAATTCGTGGGCCCCGTGG	PROKR1	ENSG00000169618	1.1468671363774732	[518,404]	[460,348]	6	hSpCas9	negative selection	4764651
68645979	68646001	2	-	27760321	HT29	viability after 7 days	GCAAAGAACGTCCTGGAATTGG	PROKR1	ENSG00000169618	0.4074639124423741	[331,258]	[556,598,366]	6	hSpCas9	negative selection	4848110
68646079	68646101	2	-	27760321	HT29	viability after 7 days	CAGTTTCTTGTAGCGGACCAGG	PROKR1	ENSG00000169618	-0.30491080997597914	[631,492]	[628,622,511]	-4	hSpCas9	negative selection	4848111
68654895	68654917	2	-	27760321	HT29	viability after 7 days	CATCCGTGGTCTCAGCGGATGG	PROKR1	ENSG00000169618	0.46318120514038685	[618,482]	[957,1125,845]	7	hSpCas9	negative selection	4848112
68654908	68654930	2	-	27760321	HT29	viability after 7 days	CTGTTTGGCACTTCATCCGTGG	PROKR1	ENSG00000169618	0.17133798372968045	[897,700]	[1338,1289,876]	2	hSpCas9	negative selection	4848113
68655109	68655131	2	+	27760321	HT29	viability after 7 days	ATAGAATTCGTGGGCCCCGTGG	PROKR1	ENSG00000169618	0.08965005735183229	[518,404]	[927,424,585]	1	hSpCas9	negative selection	4848114
68645979	68646001	2	-	27760321	HT29	viability after 25 days	GCAAAGAACGTCCTGGAATTGG	PROKR1	ENSG00000169618	0.44466520380132335	[331,258]	[504,498,360]	5	hSpCas9	negative selection	4931573
68646079	68646101	2	-	27760321	HT29	viability after 25 days	CAGTTTCTTGTAGCGGACCAGG	PROKR1	ENSG00000169618	-0.06505095725193866	[631,492]	[759,590,466]	0	hSpCas9	negative selection	4931574
68654895	68654917	2	-	27760321	HT29	viability after 25 days	CATCCGTGGTCTCAGCGGATGG	PROKR1	ENSG00000169618	-0.19542233325200548	[618,482]	[690,407,539]	-2	hSpCas9	negative selection	4931575
68654908	68654930	2	-	27760321	HT29	viability after 25 days	CTGTTTGGCACTTCATCCGTGG	PROKR1	ENSG00000169618	0.14855636796405358	[897,700]	[1271,860,872]	1	hSpCas9	negative selection	4931576
68655109	68655131	2	+	27760321	HT29	viability after 25 days	ATAGAATTCGTGGGCCCCGTGG	PROKR1	ENSG00000169618	0.6541426125746128	[518,404]	[584,968,966]	7	hSpCas9	negative selection	4931577
68645979	68646001	2	-	27760321	HT29	viability after 22 days	GCAAAGAACGTCCTGGAATTGG	PROKR1	ENSG00000169618	0.8178425065515078	[331,258]	[650,672,479]	8	hSpCas9	negative selection	5015036
68646079	68646101	2	-	27760321	HT29	viability after 22 days	CAGTTTCTTGTAGCGGACCAGG	PROKR1	ENSG00000169618	-0.39334005821534535	[631,492]	[502,592,387]	-4	hSpCas9	negative selection	5015037
68654895	68654917	2	-	27760321	HT29	viability after 22 days	CATCCGTGGTCTCAGCGGATGG	PROKR1	ENSG00000169618	-0.43106369641467457	[618,482]	[563,468,380]	-4	hSpCas9	negative selection	5015038
68654908	68654930	2	-	27760321	HT29	viability after 22 days	CTGTTTGGCACTTCATCCGTGG	PROKR1	ENSG00000169618	0.017757017165425326	[897,700]	[896,783,1128]	0	hSpCas9	negative selection	5015039
68655109	68655131	2	+	27760321	HT29	viability after 22 days	ATAGAATTCGTGGGCCCCGTGG	PROKR1	ENSG00000169618	0.6098555888558472	[518,404]	[724,973,747]	6	hSpCas9	negative selection	5015040
68645979	68646001	2	-	27760321	HT29	viability after 19 days	GCAAAGAACGTCCTGGAATTGG	PROKR1	ENSG00000169618	0.6840920060013944	[331,258]	[579,604,450]	7	hSpCas9	negative selection	5098499
68646079	68646101	2	-	27760321	HT29	viability after 19 days	CAGTTTCTTGTAGCGGACCAGG	PROKR1	ENSG00000169618	-0.2902785265663733	[631,492]	[750,448,405]	-3	hSpCas9	negative selection	5098500
68654895	68654917	2	-	27760321	HT29	viability after 19 days	CATCCGTGGTCTCAGCGGATGG	PROKR1	ENSG00000169618	0.018623380844115744	[618,482]	[873,660,412]	0	hSpCas9	negative selection	5098501
68654908	68654930	2	-	27760321	HT29	viability after 19 days	CTGTTTGGCACTTCATCCGTGG	PROKR1	ENSG00000169618	0.08089805841720898	[897,700]	[1117,978,824]	0	hSpCas9	negative selection	5098502
68655109	68655131	2	+	27760321	HT29	viability after 19 days	ATAGAATTCGTGGGCCCCGTGG	PROKR1	ENSG00000169618	1.116255806506943	[518,404]	[963,1748,719]	9	hSpCas9	negative selection	5098503
68645979	68646001	2	-	27760321	HT29	viability after 16 days	GCAAAGAACGTCCTGGAATTGG	PROKR1	ENSG00000169618	0.9794347790182125	[331,258]	[611,484,858]	9	hSpCas9	negative selection	5181962
68646079	68646101	2	-	27760321	HT29	viability after 16 days	CAGTTTCTTGTAGCGGACCAGG	PROKR1	ENSG00000169618	-0.05559317948584164	[631,492]	[1128,448,291]	0	hSpCas9	negative selection	5181963
68654895	68654917	2	-	27760321	HT29	viability after 16 days	CATCCGTGGTCTCAGCGGATGG	PROKR1	ENSG00000169618	-0.23404103002018845	[618,482]	[479,606,478]	-3	hSpCas9	negative selection	5181964
68654908	68654930	2	-	27760321	HT29	viability after 16 days	CTGTTTGGCACTTCATCCGTGG	PROKR1	ENSG00000169618	-0.011952870007157168	[897,700]	[1089,862,727]	0	hSpCas9	negative selection	5181965
68655109	68655131	2	+	27760321	HT29	viability after 16 days	ATAGAATTCGTGGGCCCCGTGG	PROKR1	ENSG00000169618	0.4920756056864987	[518,404]	[981,646,577]	5	hSpCas9	negative selection	5181966
68645979	68646001	2	-	27760321	HT29	viability after 13 days	GCAAAGAACGTCCTGGAATTGG	PROKR1	ENSG00000169618	1.0428944006629377	[331,258]	[973,520,627]	9	hSpCas9	negative selection	5265425
68646079	68646101	2	-	27760321	HT29	viability after 13 days	CAGTTTCTTGTAGCGGACCAGG	PROKR1	ENSG00000169618	-0.31369200430361377	[631,492]	[521,732,331]	-4	hSpCas9	negative selection	5265426
68654895	68654917	2	-	27760321	HT29	viability after 13 days	CATCCGTGGTCTCAGCGGATGG	PROKR1	ENSG00000169618	0.03956229319082738	[618,482]	[811,595,567]	0	hSpCas9	negative selection	5265427
68654908	68654930	2	-	27760321	HT29	viability after 13 days	CTGTTTGGCACTTCATCCGTGG	PROKR1	ENSG00000169618	0.27460139023701835	[897,700]	[1283,1157,934]	3	hSpCas9	negative selection	5265428
68655109	68655131	2	+	27760321	HT29	viability after 13 days	ATAGAATTCGTGGGCCCCGTGG	PROKR1	ENSG00000169618	0.5754671167436649	[518,404]	[748,1001,653]	7	hSpCas9	negative selection	5265429
68645979	68646001	2	-	27760321	HT29	viability after 10 days	GCAAAGAACGTCCTGGAATTGG	PROKR1	ENSG00000169618	0.32910845662684063	[331,258]	[580,403,404]	4	hSpCas9	negative selection	5348888
68646079	68646101	2	-	27760321	HT29	viability after 10 days	CAGTTTCTTGTAGCGGACCAGG	PROKR1	ENSG00000169618	-0.6873151789025436	[631,492]	[509,476,324]	-7	hSpCas9	negative selection	5348889
68654895	68654917	2	-	27760321	HT29	viability after 10 days	CATCCGTGGTCTCAGCGGATGG	PROKR1	ENSG00000169618	0.23630761570544012	[618,482]	[816,686,920]	3	hSpCas9	negative selection	5348890
68654908	68654930	2	-	27760321	HT29	viability after 10 days	CTGTTTGGCACTTCATCCGTGG	PROKR1	ENSG00000169618	-0.07091780094096944	[897,700]	[907,1211,742]	-1	hSpCas9	negative selection	5348891
68655109	68655131	2	+	27760321	HT29	viability after 10 days	ATAGAATTCGTGGGCCCCGTGG	PROKR1	ENSG00000169618	0.417085266372263	[518,404]	[959,635,711]	5	hSpCas9	negative selection	5348892
68645979	68646001	2	-	27760321	MOLM13	viability	GCAAAGAACGTCCTGGAATTGG	PROKR1	ENSG00000169618	-0.010997786051500646	[386,331]	[251,156]	0	hSpCas9	negative selection	5432351
68646079	68646101	2	-	27760321	MOLM13	viability	CAGTTTCTTGTAGCGGACCAGG	PROKR1	ENSG00000169618	0.6463097074100416	[720,631]	[385,774]	4	hSpCas9	negative selection	5432352
68654895	68654917	2	-	27760321	MOLM13	viability	CATCCGTGGTCTCAGCGGATGG	PROKR1	ENSG00000169618	0.7770420624229436	[682,618]	[824,461]	5	hSpCas9	negative selection	5432353
68654908	68654930	2	-	27760321	MOLM13	viability	CTGTTTGGCACTTCATCCGTGG	PROKR1	ENSG00000169618	1.0033576086798852	[1055,897]	[1641,640]	7	hSpCas9	negative selection	5432354
68655109	68655131	2	+	27760321	MOLM13	viability	ATAGAATTCGTGGGCCCCGTGG	PROKR1	ENSG00000169618	-0.07758574689300207	[705,518]	[499,174]	0	hSpCas9	negative selection	5432355
68655305	68655328	2	-	27260156	BXPC3	viability	GGGGAAGAAGTCGCGCACGATGG	PROKR1	ENSG00000169618	-1.084504204402712	[77]	[20,36,25,75]	-9	hSpCas9	negative selection	5564765
68655108	68655131	2	+	27260156	BXPC3	viability	CATAGAATTCGTGGGCCCCGTGG	PROKR1	ENSG00000169618	-0.08386857323048569	[268]	[258,214,253,344]	-2	hSpCas9	negative selection	5564766
68645938	68645961	2	+	27260156	BXPC3	viability	CAGCGACTATGATATGCCTTTGG	PROKR1	ENSG00000169618	-0.21829386708504828	[252]	[212,201,184,321]	-5	hSpCas9	negative selection	5564767
68645985	68646008	2	-	27260156	BXPC3	viability	CTTGGCAGCAAAGAACGTCCTGG	PROKR1	ENSG00000169618	-0.3688579405918337	[447]	[358,367,303,423]	-7	hSpCas9	negative selection	5629024
68655269	68655292	2	-	27260156	BXPC3	viability	GGGCGCCCAGCATAGCACGTAGG	PROKR1	ENSG00000169618	-0.23397935686224036	[158]	[172,114,102,174]	-5	hSpCas9	negative selection	5629025
68654945	68654968	2	-	27260156	BXPC3	viability	GATGGACACCGTCCACACCAAGG	PROKR1	ENSG00000169618	0.026226891213686487	[608]	[517,603,694,809]	0	hSpCas9	negative selection	5629026
68655305	68655328	2	-	27260156	A673	viability	GGGGAAGAAGTCGCGCACGATGG	PROKR1	ENSG00000169618	-0.35370248685641803	[77]	[66,49,67,109]	-7	hSpCas9	negative selection	5686016
68655108	68655131	2	+	27260156	A673	viability	CATAGAATTCGTGGGCCCCGTGG	PROKR1	ENSG00000169618	0.2373086273758035	[268]	[520,299,468,241]	5	hSpCas9	negative selection	5686017
68645938	68645961	2	+	27260156	A673	viability	CAGCGACTATGATATGCCTTTGG	PROKR1	ENSG00000169618	-0.24232101781075355	[252]	[199,214,252,358]	-5	hSpCas9	negative selection	5686018
68645985	68646008	2	-	27260156	A673	viability	CTTGGCAGCAAAGAACGTCCTGG	PROKR1	ENSG00000169618	0.1432927905731884	[447]	[565,522,586,703]	3	hSpCas9	negative selection	5750275
68655269	68655292	2	-	27260156	A673	viability	GGGCGCCCAGCATAGCACGTAGG	PROKR1	ENSG00000169618	-0.42229689384567215	[158]	[130,144,136,155]	-8	hSpCas9	negative selection	5750276
68654945	68654968	2	-	27260156	A673	viability	GATGGACACCGTCCACACCAAGG	PROKR1	ENSG00000169618	0.023410093703174206	[608]	[817,780,665,712]	0	hSpCas9	negative selection	5750277
68655305	68655328	2	-	27260156	A375	viability	GGGGAAGAAGTCGCGCACGATGG	PROKR1	ENSG00000169618	0.017813891566472506	[77]	[119,139,46,70]	0	hSpCas9	negative selection	5807267
68655108	68655131	2	+	27260156	A375	viability	CATAGAATTCGTGGGCCCCGTGG	PROKR1	ENSG00000169618	0.6598605860214455	[268]	[428,685,300,582]	8	hSpCas9	negative selection	5807268
68645938	68645961	2	+	27260156	A375	viability	CAGCGACTATGATATGCCTTTGG	PROKR1	ENSG00000169618	-0.37092751726323603	[252]	[187,218,261,240]	-5	hSpCas9	negative selection	5807269
68645985	68646008	2	-	27260156	A375	viability	CTTGGCAGCAAAGAACGTCCTGG	PROKR1	ENSG00000169618	0.0690159366650852	[447]	[410,756,500,551]	1	hSpCas9	negative selection	5871526
68655269	68655292	2	-	27260156	A375	viability	GGGCGCCCAGCATAGCACGTAGG	PROKR1	ENSG00000169618	-0.6342702058120748	[158]	[80,120,72,193]	-7	hSpCas9	negative selection	5871527
68654945	68654968	2	-	27260156	A375	viability	GATGGACACCGTCCACACCAAGG	PROKR1	ENSG00000169618	0.08926307090990038	[608]	[936,973,651,520]	1	hSpCas9	negative selection	5871528
68655305	68655328	2	-	27260156	COLO741	viability	GGGGAAGAAGTCGCGCACGATGG	PROKR1	ENSG00000169618	-0.8962407535481738	[77]	[94,43,26]	-9	hSpCas9	negative selection	5928518
68655108	68655131	2	+	27260156	COLO741	viability	CATAGAATTCGTGGGCCCCGTGG	PROKR1	ENSG00000169618	0.11356067245861656	[268]	[365,400,348]	2	hSpCas9	negative selection	5928519
68645938	68645961	2	+	27260156	COLO741	viability	CAGCGACTATGATATGCCTTTGG	PROKR1	ENSG00000169618	-0.6800856217377671	[252]	[152,262,185]	-8	hSpCas9	negative selection	5928520
68645985	68646008	2	-	27260156	COLO741	viability	CTTGGCAGCAAAGAACGTCCTGG	PROKR1	ENSG00000169618	0.04302755159782047	[447]	[775,482,528]	0	hSpCas9	negative selection	5992777
68655269	68655292	2	-	27260156	COLO741	viability	GGGCGCCCAGCATAGCACGTAGG	PROKR1	ENSG00000169618	-0.41260281236268304	[158]	[155,123,175]	-7	hSpCas9	negative selection	5992778
68654945	68654968	2	-	27260156	COLO741	viability	GATGGACACCGTCCACACCAAGG	PROKR1	ENSG00000169618	0.07790682730170223	[608]	[1010,871,610]	1	hSpCas9	negative selection	5992779
68655305	68655328	2	-	27260156	CAL120	viability	GGGGAAGAAGTCGCGCACGATGG	PROKR1	ENSG00000169618	-0.21778024395484197	[77]	[35,55,149]	-3	hSpCas9	negative selection	6049769
68655108	68655131	2	+	27260156	CAL120	viability	CATAGAATTCGTGGGCCCCGTGG	PROKR1	ENSG00000169618	0.17834430575836902	[268]	[350,400,379]	2	hSpCas9	negative selection	6049770
68645938	68645961	2	+	27260156	CAL120	viability	CAGCGACTATGATATGCCTTTGG	PROKR1	ENSG00000169618	0.1553476896582645	[252]	[476,145,445]	2	hSpCas9	negative selection	6049771
68645985	68646008	2	-	27260156	CAL120	viability	CTTGGCAGCAAAGAACGTCCTGG	PROKR1	ENSG00000169618	0.059444932049681265	[447]	[794,690,293]	0	hSpCas9	negative selection	6114028
68655269	68655292	2	-	27260156	CAL120	viability	GGGCGCCCAGCATAGCACGTAGG	PROKR1	ENSG00000169618	-0.266886767377843	[158]	[370,81,72]	-4	hSpCas9	negative selection	6114029
68654945	68654968	2	-	27260156	CAL120	viability	GATGGACACCGTCCACACCAAGG	PROKR1	ENSG00000169618	0.0759783371635202	[608]	[1280,575,614]	1	hSpCas9	negative selection	6114030
68655305	68655328	2	-	27260156	CADOES1	viability	GGGGAAGAAGTCGCGCACGATGG	PROKR1	ENSG00000169618	0.6232594081331775	[77]	[91,71,92,192]	8	hSpCas9	negative selection	6171020
68655108	68655131	2	+	27260156	CADOES1	viability	CATAGAATTCGTGGGCCCCGTGG	PROKR1	ENSG00000169618	0.19052748912761974	[268]	[248,351,287,251]	3	hSpCas9	negative selection	6171021
68645938	68645961	2	+	27260156	CADOES1	viability	CAGCGACTATGATATGCCTTTGG	PROKR1	ENSG00000169618	-0.8986172633875393	[252]	[100,126,97,180]	-9	hSpCas9	negative selection	6171022
68645985	68646008	2	-	27260156	CADOES1	viability	CTTGGCAGCAAAGAACGTCCTGG	PROKR1	ENSG00000169618	0.1424707261754164	[447]	[541,430,492,369]	2	hSpCas9	negative selection	6235279
68655269	68655292	2	-	27260156	CADOES1	viability	GGGCGCCCAGCATAGCACGTAGG	PROKR1	ENSG00000169618	-0.6289765003418082	[158]	[136,104,80,57]	-8	hSpCas9	negative selection	6235280
68654945	68654968	2	-	27260156	CADOES1	viability	GATGGACACCGTCCACACCAAGG	PROKR1	ENSG00000169618	0.12553164606629041	[608]	[484,618,670,699]	2	hSpCas9	negative selection	6235281
68655305	68655328	2	-	27260156	EWS502	viability	GGGGAAGAAGTCGCGCACGATGG	PROKR1	ENSG00000169618	-0.31606625946026456	[77]	[73,60,53,75]	-5	hSpCas9	negative selection	6292271
68655108	68655131	2	+	27260156	EWS502	viability	CATAGAATTCGTGGGCCCCGTGG	PROKR1	ENSG00000169618	-0.025483729738534633	[268]	[234,258,334,297]	0	hSpCas9	negative selection	6292272
68645938	68645961	2	+	27260156	EWS502	viability	CAGCGACTATGATATGCCTTTGG	PROKR1	ENSG00000169618	-0.17369864960848158	[252]	[191,225,352,181]	-3	hSpCas9	negative selection	6292273
68645985	68646008	2	-	27260156	EWS502	viability	CTTGGCAGCAAAGAACGTCCTGG	PROKR1	ENSG00000169618	-0.053133293703598095	[447]	[463,293,487,597]	-1	hSpCas9	negative selection	6356530
68655269	68655292	2	-	27260156	EWS502	viability	GGGCGCCCAGCATAGCACGTAGG	PROKR1	ENSG00000169618	-0.3339321254270806	[158]	[73,178,97,191]	-5	hSpCas9	negative selection	6356531
68654945	68654968	2	-	27260156	EWS502	viability	GATGGACACCGTCCACACCAAGG	PROKR1	ENSG00000169618	0.05561811252500343	[608]	[691,642,727,610]	1	hSpCas9	negative selection	6356532
68655305	68655328	2	-	27260156	EW8	viability	GGGGAAGAAGTCGCGCACGATGG	PROKR1	ENSG00000169618	-0.27743898051473037	[77]	[65,23,80,33]	-5	hSpCas9	negative selection	6413522
68655108	68655131	2	+	27260156	EW8	viability	CATAGAATTCGTGGGCCCCGTGG	PROKR1	ENSG00000169618	0.05039610257914384	[268]	[277,220,178,237]	0	hSpCas9	negative selection	6413523
68645938	68645961	2	+	27260156	EW8	viability	CAGCGACTATGATATGCCTTTGG	PROKR1	ENSG00000169618	-0.5205903123886375	[252]	[248,109,106,122]	-7	hSpCas9	negative selection	6413524
68645985	68646008	2	-	27260156	EW8	viability	CTTGGCAGCAAAGAACGTCCTGG	PROKR1	ENSG00000169618	-0.2156397779283596	[447]	[355,347,245,315]	-4	hSpCas9	negative selection	6477781
68655269	68655292	2	-	27260156	EW8	viability	GGGCGCCCAGCATAGCACGTAGG	PROKR1	ENSG00000169618	-0.10897232084198039	[158]	[163,181,83,58]	-2	hSpCas9	negative selection	6477782
68654945	68654968	2	-	27260156	EW8	viability	GATGGACACCGTCCACACCAAGG	PROKR1	ENSG00000169618	-0.09324478678449671	[608]	[650,466,351,418]	-2	hSpCas9	negative selection	6477783
68655305	68655328	2	-	27260156	CORL105	viability	GGGGAAGAAGTCGCGCACGATGG	PROKR1	ENSG00000169618	-0.07195385866563031	[77]	[75,48,182,54]	-1	hSpCas9	negative selection	6534773
68655108	68655131	2	+	27260156	CORL105	viability	CATAGAATTCGTGGGCCCCGTGG	PROKR1	ENSG00000169618	0.2146886827589527	[268]	[505,311,359,288]	4	hSpCas9	negative selection	6534774
68645938	68645961	2	+	27260156	CORL105	viability	CAGCGACTATGATATGCCTTTGG	PROKR1	ENSG00000169618	-0.056983520609321325	[252]	[263,242,380,265]	-1	hSpCas9	negative selection	6534775
68645985	68646008	2	-	27260156	CORL105	viability	CTTGGCAGCAAAGAACGTCCTGG	PROKR1	ENSG00000169618	-0.1642886474748555	[447]	[540,365,559,423]	-3	hSpCas9	negative selection	6599032
68655269	68655292	2	-	27260156	CORL105	viability	GGGCGCCCAGCATAGCACGTAGG	PROKR1	ENSG00000169618	-0.27678518670149677	[158]	[94,145,144,224]	-5	hSpCas9	negative selection	6599033
68654945	68654968	2	-	27260156	CORL105	viability	GATGGACACCGTCCACACCAAGG	PROKR1	ENSG00000169618	-0.4099871671813435	[608]	[438,609,459,619]	-6	hSpCas9	negative selection	6599034
68655305	68655328	2	-	27260156	HS294T	viability	GGGGAAGAAGTCGCGCACGATGG	PROKR1	ENSG00000169618	-0.46644216053042475	[77]	[18,22,20,24]	-6	hSpCas9	negative selection	6656024
68655108	68655131	2	+	27260156	HS294T	viability	CATAGAATTCGTGGGCCCCGTGG	PROKR1	ENSG00000169618	0.9360358304193321	[268]	[65,453,97,177]	9	hSpCas9	negative selection	6656025
68645938	68645961	2	+	27260156	HS294T	viability	CAGCGACTATGATATGCCTTTGG	PROKR1	ENSG00000169618	-0.06645316341935636	[252]	[77,130,53,113]	-1	hSpCas9	negative selection	6656026
68645985	68646008	2	-	27260156	HS294T	viability	CTTGGCAGCAAAGAACGTCCTGG	PROKR1	ENSG00000169618	0.364621611382332	[447]	[158,225,231,291]	5	hSpCas9	negative selection	6720283
68655269	68655292	2	-	27260156	HS294T	viability	GGGCGCCCAGCATAGCACGTAGG	PROKR1	ENSG00000169618	0.027420619761206355	[158]	[114,53,36,34]	0	hSpCas9	negative selection	6720284
68654945	68654968	2	-	27260156	HS294T	viability	GATGGACACCGTCCACACCAAGG	PROKR1	ENSG00000169618	-0.5012756073117599	[608]	[129,219,142,174]	-6	hSpCas9	negative selection	6720285
68655305	68655328	2	-	27260156	HCC44	viability	GGGGAAGAAGTCGCGCACGATGG	PROKR1	ENSG00000169618	-0.3162329249673319	[77]	[77,90,82,31]	-5	hSpCas9	negative selection	6777275
68655108	68655131	2	+	27260156	HCC44	viability	CATAGAATTCGTGGGCCCCGTGG	PROKR1	ENSG00000169618	0.12968117468647833	[268]	[271,339,424,301]	2	hSpCas9	negative selection	6777276
68645938	68645961	2	+	27260156	HCC44	viability	CAGCGACTATGATATGCCTTTGG	PROKR1	ENSG00000169618	-0.1422479167980486	[252]	[299,190,423,164]	-2	hSpCas9	negative selection	6777277
68645985	68646008	2	-	27260156	HCC44	viability	CTTGGCAGCAAAGAACGTCCTGG	PROKR1	ENSG00000169618	0.03736097965911896	[447]	[558,433,762,381]	0	hSpCas9	negative selection	6841534
68655269	68655292	2	-	27260156	HCC44	viability	GGGCGCCCAGCATAGCACGTAGG	PROKR1	ENSG00000169618	-0.9026235964264155	[158]	[72,66,164,92]	-8	hSpCas9	negative selection	6841535
68654945	68654968	2	-	27260156	HCC44	viability	GATGGACACCGTCCACACCAAGG	PROKR1	ENSG00000169618	-0.14265326487185842	[608]	[533,521,680,764]	-2	hSpCas9	negative selection	6841536
68655305	68655328	2	-	27260156	G402	viability	GGGGAAGAAGTCGCGCACGATGG	PROKR1	ENSG00000169618	-0.8855194994994138	[77]	[65,87,23,32]	-8	hSpCas9	negative selection	6898526
68655108	68655131	2	+	27260156	G402	viability	CATAGAATTCGTGGGCCCCGTGG	PROKR1	ENSG00000169618	-0.2063145928259713	[268]	[494,219,173,274]	-3	hSpCas9	negative selection	6898527
68645938	68645961	2	+	27260156	G402	viability	CAGCGACTATGATATGCCTTTGG	PROKR1	ENSG00000169618	0.5386549606754485	[252]	[636,258,140,755]	6	hSpCas9	negative selection	6898528
68645985	68646008	2	-	27260156	G402	viability	CTTGGCAGCAAAGAACGTCCTGG	PROKR1	ENSG00000169618	-0.20502802355339772	[447]	[555,471,557,327]	-3	hSpCas9	negative selection	6962785
68655269	68655292	2	-	27260156	G402	viability	GGGCGCCCAGCATAGCACGTAGG	PROKR1	ENSG00000169618	-1.6965999534637524	[158]	[49,22,25,132]	-9	hSpCas9	negative selection	6962786
68654945	68654968	2	-	27260156	G402	viability	GATGGACACCGTCCACACCAAGG	PROKR1	ENSG00000169618	0.04757039557069903	[608]	[991,1247,474,430]	0	hSpCas9	negative selection	6962787
68655305	68655328	2	-	27260156	L33	viability	GGGGAAGAAGTCGCGCACGATGG	PROKR1	ENSG00000169618	-0.39354817568611944	[77]	[59,30,45,28]	-7	hSpCas9	negative selection	7019777
68655108	68655131	2	+	27260156	L33	viability	CATAGAATTCGTGGGCCCCGTGG	PROKR1	ENSG00000169618	0.33441149009376664	[268]	[298,154,204,353]	7	hSpCas9	negative selection	7019778
68645938	68645961	2	+	27260156	L33	viability	CAGCGACTATGATATGCCTTTGG	PROKR1	ENSG00000169618	-0.4223051665263522	[252]	[186,55,121,236]	-7	hSpCas9	negative selection	7019779
68645985	68646008	2	-	27260156	L33	viability	CTTGGCAGCAAAGAACGTCCTGG	PROKR1	ENSG00000169618	0.025811974454753063	[447]	[578,174,278,371]	0	hSpCas9	negative selection	7084036
68655269	68655292	2	-	27260156	L33	viability	GGGCGCCCAGCATAGCACGTAGG	PROKR1	ENSG00000169618	-0.2212617059512334	[158]	[122,54,95,135]	-5	hSpCas9	negative selection	7084037
68654945	68654968	2	-	27260156	L33	viability	GATGGACACCGTCCACACCAAGG	PROKR1	ENSG00000169618	-0.09223728677009246	[608]	[500,301,343,501]	-2	hSpCas9	negative selection	7084038
68655305	68655328	2	-	27260156	K562	viability	GGGGAAGAAGTCGCGCACGATGG	PROKR1	ENSG00000169618	-1.1341051313526411	[77]	[25,37,2,55]	-8	hSpCas9	negative selection	7141028
68655108	68655131	2	+	27260156	K562	viability	CATAGAATTCGTGGGCCCCGTGG	PROKR1	ENSG00000169618	-0.058814346628774716	[268]	[455,322,107,70]	0	hSpCas9	negative selection	7141029
68645938	68645961	2	+	27260156	K562	viability	CAGCGACTATGATATGCCTTTGG	PROKR1	ENSG00000169618	0.22787903434398493	[252]	[261,235,418,145]	3	hSpCas9	negative selection	7141030
68645985	68646008	2	-	27260156	K562	viability	CTTGGCAGCAAAGAACGTCCTGG	PROKR1	ENSG00000169618	0.22818480250630585	[447]	[421,434,564,436]	3	hSpCas9	negative selection	7205287
68655269	68655292	2	-	27260156	K562	viability	GGGCGCCCAGCATAGCACGTAGG	PROKR1	ENSG00000169618	-0.4398205342474877	[158]	[100,86,145,82]	-5	hSpCas9	negative selection	7205288
68654945	68654968	2	-	27260156	K562	viability	GATGGACACCGTCCACACCAAGG	PROKR1	ENSG00000169618	0.1374622967939157	[608]	[501,598,530,720]	1	hSpCas9	negative selection	7205289
68655305	68655328	2	-	27260156	HT29	viability	GGGGAAGAAGTCGCGCACGATGG	PROKR1	ENSG00000169618	0.14202285701917994	[77]	[146,91,94,87]	2	hSpCas9	negative selection	7262279
68655108	68655131	2	+	27260156	HT29	viability	CATAGAATTCGTGGGCCCCGTGG	PROKR1	ENSG00000169618	0.3114249081315058	[268]	[528,326,415,356]	6	hSpCas9	negative selection	7262280
68645938	68645961	2	+	27260156	HT29	viability	CAGCGACTATGATATGCCTTTGG	PROKR1	ENSG00000169618	-0.19320726202795968	[252]	[269,271,268,263]	-4	hSpCas9	negative selection	7262281
68645985	68646008	2	-	27260156	HT29	viability	CTTGGCAGCAAAGAACGTCCTGG	PROKR1	ENSG00000169618	0.19693687163627782	[447]	[593,679,785,455]	4	hSpCas9	negative selection	7326538
68655269	68655292	2	-	27260156	HT29	viability	GGGCGCCCAGCATAGCACGTAGG	PROKR1	ENSG00000169618	-0.28405568646857726	[158]	[203,207,155,82]	-5	hSpCas9	negative selection	7326539
68654945	68654968	2	-	27260156	HT29	viability	GATGGACACCGTCCACACCAAGG	PROKR1	ENSG00000169618	-0.02424680504558957	[608]	[835,754,784,561]	0	hSpCas9	negative selection	7326540
68655305	68655328	2	-	27260156	MHHES1	viability	GGGGAAGAAGTCGCGCACGATGG	PROKR1	ENSG00000169618	-0.4325719989650807	[77]	[8,105,94,49]	-7	hSpCas9	negative selection	7383530
68655108	68655131	2	+	27260156	MHHES1	viability	CATAGAATTCGTGGGCCCCGTGG	PROKR1	ENSG00000169618	0.3184927985449088	[268]	[291,485,337,384]	6	hSpCas9	negative selection	7383531
68645938	68645961	2	+	27260156	MHHES1	viability	CAGCGACTATGATATGCCTTTGG	PROKR1	ENSG00000169618	-0.27780548390613613	[252]	[211,232,257,229]	-5	hSpCas9	negative selection	7383532
68645985	68646008	2	-	27260156	MHHES1	viability	CTTGGCAGCAAAGAACGTCCTGG	PROKR1	ENSG00000169618	0.18883203414903782	[447]	[544,718,719,364]	3	hSpCas9	negative selection	7447789
68655269	68655292	2	-	27260156	MHHES1	viability	GGGCGCCCAGCATAGCACGTAGG	PROKR1	ENSG00000169618	-1.0860383865154302	[158]	[101,89,91,59]	-9	hSpCas9	negative selection	7447790
68654945	68654968	2	-	27260156	MHHES1	viability	GATGGACACCGTCCACACCAAGG	PROKR1	ENSG00000169618	-0.02159284059216432	[608]	[832,774,655,494]	0	hSpCas9	negative selection	7447791
68655305	68655328	2	-	27260156	MEWO	viability	GGGGAAGAAGTCGCGCACGATGG	PROKR1	ENSG00000169618	0.18771788771264797	[77]	[40,116,82]	4	hSpCas9	negative selection	7504781
68655108	68655131	2	+	27260156	MEWO	viability	CATAGAATTCGTGGGCCCCGTGG	PROKR1	ENSG00000169618	-0.11143759129951314	[268]	[269,232,202]	-2	hSpCas9	negative selection	7504782
68645938	68645961	2	+	27260156	MEWO	viability	CAGCGACTATGATATGCCTTTGG	PROKR1	ENSG00000169618	-0.04531335764155475	[252]	[244,251,193]	-1	hSpCas9	negative selection	7504783
68645985	68646008	2	-	27260156	MEWO	viability	CTTGGCAGCAAAGAACGTCCTGG	PROKR1	ENSG00000169618	0.22334764913872251	[447]	[660,506,332]	5	hSpCas9	negative selection	7569040
68655269	68655292	2	-	27260156	MEWO	viability	GGGCGCCCAGCATAGCACGTAGG	PROKR1	ENSG00000169618	-0.22067957546504924	[158]	[111,107,159]	-5	hSpCas9	negative selection	7569041
68654945	68654968	2	-	27260156	MEWO	viability	GATGGACACCGTCCACACCAAGG	PROKR1	ENSG00000169618	0.05127791248830388	[608]	[644,501,634]	1	hSpCas9	negative selection	7569042
68655305	68655328	2	-	27260156	LNCAPCLONEFGC	viability	GGGGAAGAAGTCGCGCACGATGG	PROKR1	ENSG00000169618	-0.3611361950438221	[77]	[33,48,89,52]	-5	hSpCas9	negative selection	7626032
68655108	68655131	2	+	27260156	LNCAPCLONEFGC	viability	CATAGAATTCGTGGGCCCCGTGG	PROKR1	ENSG00000169618	0.41196609827508274	[268]	[420,223,341,316]	6	hSpCas9	negative selection	7626033
68645938	68645961	2	+	27260156	LNCAPCLONEFGC	viability	CAGCGACTATGATATGCCTTTGG	PROKR1	ENSG00000169618	0.09555883765538564	[252]	[151,246,318,273]	1	hSpCas9	negative selection	7626034
68645985	68646008	2	-	27260156	LNCAPCLONEFGC	viability	CTTGGCAGCAAAGAACGTCCTGG	PROKR1	ENSG00000169618	0.32588881990388274	[447]	[621,441,477,489]	5	hSpCas9	negative selection	7690291
68655269	68655292	2	-	27260156	LNCAPCLONEFGC	viability	GGGCGCCCAGCATAGCACGTAGG	PROKR1	ENSG00000169618	-0.05147180947808372	[158]	[164,140,76,162]	-1	hSpCas9	negative selection	7690292
68654945	68654968	2	-	27260156	LNCAPCLONEFGC	viability	GATGGACACCGTCCACACCAAGG	PROKR1	ENSG00000169618	-0.1116071442613622	[608]	[448,508,514,570]	-2	hSpCas9	negative selection	7690293
68655305	68655328	2	-	27260156	PANC0327	viability	GGGGAAGAAGTCGCGCACGATGG	PROKR1	ENSG00000169618	0.714581136168774	[77]	[181,162,75,32]	8	hSpCas9	negative selection	7747283
68655108	68655131	2	+	27260156	PANC0327	viability	CATAGAATTCGTGGGCCCCGTGG	PROKR1	ENSG00000169618	-0.04865218460420484	[268]	[262,180,181,306]	0	hSpCas9	negative selection	7747284
68645938	68645961	2	+	27260156	PANC0327	viability	CAGCGACTATGATATGCCTTTGG	PROKR1	ENSG00000169618	0.09647259975053013	[252]	[250,176,209,331]	1	hSpCas9	negative selection	7747285
68645985	68646008	2	-	27260156	PANC0327	viability	CTTGGCAGCAAAGAACGTCCTGG	PROKR1	ENSG00000169618	0.03603723638951411	[447]	[390,281,510,462]	0	hSpCas9	negative selection	7811542
68655269	68655292	2	-	27260156	PANC0327	viability	GGGCGCCCAGCATAGCACGTAGG	PROKR1	ENSG00000169618	-1.7074259867661907	[158]	[66,34,41,31]	-9	hSpCas9	negative selection	7811543
68654945	68654968	2	-	27260156	PANC0327	viability	GATGGACACCGTCCACACCAAGG	PROKR1	ENSG00000169618	-0.07297645311293255	[608]	[426,758,340,490]	-1	hSpCas9	negative selection	7811544
68655305	68655328	2	-	27260156	NCIH2009	viability	GGGGAAGAAGTCGCGCACGATGG	PROKR1	ENSG00000169618	-0.4170431664217946	[77]	[185,45,33]	-5	hSpCas9	negative selection	7868534
68655108	68655131	2	+	27260156	NCIH2009	viability	CATAGAATTCGTGGGCCCCGTGG	PROKR1	ENSG00000169618	0.12454806795927942	[268]	[398,318,509]	1	hSpCas9	negative selection	7868535
68645938	68645961	2	+	27260156	NCIH2009	viability	CAGCGACTATGATATGCCTTTGG	PROKR1	ENSG00000169618	-0.22060378015123616	[252]	[430,346,155]	-3	hSpCas9	negative selection	7868536
68645985	68646008	2	-	27260156	NCIH2009	viability	CTTGGCAGCAAAGAACGTCCTGG	PROKR1	ENSG00000169618	-0.005705423606714499	[447]	[757,562,575]	0	hSpCas9	negative selection	7932793
68655269	68655292	2	-	27260156	NCIH2009	viability	GGGCGCCCAGCATAGCACGTAGG	PROKR1	ENSG00000169618	-0.4303219235770175	[158]	[172,103,219]	-5	hSpCas9	negative selection	7932794
68654945	68654968	2	-	27260156	NCIH2009	viability	GATGGACACCGTCCACACCAAGG	PROKR1	ENSG00000169618	-0.49507892428782296	[608]	[755,504,580]	-6	hSpCas9	negative selection	7932795
68655305	68655328	2	-	27260156	NCIH1373	viability	GGGGAAGAAGTCGCGCACGATGG	PROKR1	ENSG00000169618	-0.7517951189917582	[77]	[12,10,133,11]	-6	hSpCas9	negative selection	7989785
68655108	68655131	2	+	27260156	NCIH1373	viability	CATAGAATTCGTGGGCCCCGTGG	PROKR1	ENSG00000169618	-0.014919681749155256	[268]	[201,139,479,97]	0	hSpCas9	negative selection	7989786
68645938	68645961	2	+	27260156	NCIH1373	viability	CAGCGACTATGATATGCCTTTGG	PROKR1	ENSG00000169618	0.15882590755647152	[252]	[200,265,318,124]	1	hSpCas9	negative selection	7989787
68645985	68646008	2	-	27260156	NCIH1373	viability	CTTGGCAGCAAAGAACGTCCTGG	PROKR1	ENSG00000169618	-0.25144510980441365	[447]	[341,274,570,131]	-3	hSpCas9	negative selection	8054044
68655269	68655292	2	-	27260156	NCIH1373	viability	GGGCGCCCAGCATAGCACGTAGG	PROKR1	ENSG00000169618	-1.2389818679312583	[158]	[152,69,47,10]	-8	hSpCas9	negative selection	8054045
68654945	68654968	2	-	27260156	NCIH1373	viability	GATGGACACCGTCCACACCAAGG	PROKR1	ENSG00000169618	-0.15799977030990525	[608]	[1024,386,835,67]	-1	hSpCas9	negative selection	8054046
68655305	68655328	2	-	27260156	PATU8902	viability	GGGGAAGAAGTCGCGCACGATGG	PROKR1	ENSG00000169618	-1.1540040808018852	[77]	[9,103,51,25]	-7	hSpCas9	negative selection	8111036
68655108	68655131	2	+	27260156	PATU8902	viability	CATAGAATTCGTGGGCCCCGTGG	PROKR1	ENSG00000169618	0.36413914376850764	[268]	[515,304,142,1124]	4	hSpCas9	negative selection	8111037
68645938	68645961	2	+	27260156	PATU8902	viability	CAGCGACTATGATATGCCTTTGG	PROKR1	ENSG00000169618	0.4580572913844125	[252]	[470,530,695,137]	5	hSpCas9	negative selection	8111038
68645985	68646008	2	-	27260156	PATU8902	viability	CTTGGCAGCAAAGAACGTCCTGG	PROKR1	ENSG00000169618	-0.3402187251542656	[447]	[351,281,659,649]	-3	hSpCas9	negative selection	8175295
68655269	68655292	2	-	27260156	PATU8902	viability	GGGCGCCCAGCATAGCACGTAGG	PROKR1	ENSG00000169618	-1.0530043403459395	[158]	[82,112,47,209]	-7	hSpCas9	negative selection	8175296
68654945	68654968	2	-	27260156	PATU8902	viability	GATGGACACCGTCCACACCAAGG	PROKR1	ENSG00000169618	0.03710303078906363	[608]	[575,866,971,1058]	0	hSpCas9	negative selection	8175297
68655305	68655328	2	-	27260156	PANC1	viability	GGGGAAGAAGTCGCGCACGATGG	PROKR1	ENSG00000169618	-0.24446877702044345	[77]	[84,62,29,48]	-4	hSpCas9	negative selection	8232287
68655108	68655131	2	+	27260156	PANC1	viability	CATAGAATTCGTGGGCCCCGTGG	PROKR1	ENSG00000169618	0.1289337354368446	[268]	[327,320,250,137]	2	hSpCas9	negative selection	8232288
68645938	68645961	2	+	27260156	PANC1	viability	CAGCGACTATGATATGCCTTTGG	PROKR1	ENSG00000169618	-0.2646602720603495	[252]	[186,185,191,159]	-4	hSpCas9	negative selection	8232289
68645985	68646008	2	-	27260156	PANC1	viability	CTTGGCAGCAAAGAACGTCCTGG	PROKR1	ENSG00000169618	0.07545339447881799	[447]	[316,391,566,348]	1	hSpCas9	negative selection	8296546
68655269	68655292	2	-	27260156	PANC1	viability	GGGCGCCCAGCATAGCACGTAGG	PROKR1	ENSG00000169618	-0.3043961159692161	[158]	[34,104,179,119]	-5	hSpCas9	negative selection	8296547
68654945	68654968	2	-	27260156	PANC1	viability	GATGGACACCGTCCACACCAAGG	PROKR1	ENSG00000169618	-0.024448828098687314	[608]	[617,600,616,269]	0	hSpCas9	negative selection	8296548
68655305	68655328	2	-	27260156	PANC0813	viability	GGGGAAGAAGTCGCGCACGATGG	PROKR1	ENSG00000169618	-0.380484738039923	[77]	[168,29,66,26]	-5	hSpCas9	negative selection	8353538
68655108	68655131	2	+	27260156	PANC0813	viability	CATAGAATTCGTGGGCCCCGTGG	PROKR1	ENSG00000169618	0.38300406230369705	[268]	[499,431,479,252]	6	hSpCas9	negative selection	8353539
68645938	68645961	2	+	27260156	PANC0813	viability	CAGCGACTATGATATGCCTTTGG	PROKR1	ENSG00000169618	-0.2320368544251401	[252]	[312,265,254,186]	-4	hSpCas9	negative selection	8353540
68645985	68646008	2	-	27260156	PANC0813	viability	CTTGGCAGCAAAGAACGTCCTGG	PROKR1	ENSG00000169618	0.19586083039562374	[447]	[685,448,779,508]	3	hSpCas9	negative selection	8417797
68655269	68655292	2	-	27260156	PANC0813	viability	GGGCGCCCAGCATAGCACGTAGG	PROKR1	ENSG00000169618	0.12055064472387889	[158]	[172,173,115,337]	2	hSpCas9	negative selection	8417798
68654945	68654968	2	-	27260156	PANC0813	viability	GATGGACACCGTCCACACCAAGG	PROKR1	ENSG00000169618	0.12422156418481312	[608]	[972,566,856,740]	2	hSpCas9	negative selection	8417799
68655305	68655328	2	-	27260156	RDES	viability	GGGGAAGAAGTCGCGCACGATGG	PROKR1	ENSG00000169618	-0.33035394328883694	[77]	[57,57,119,49]	-5	hSpCas9	negative selection	8474789
68655108	68655131	2	+	27260156	RDES	viability	CATAGAATTCGTGGGCCCCGTGG	PROKR1	ENSG00000169618	0.07462873945136361	[268]	[453,200,267,352]	1	hSpCas9	negative selection	8474790
68645938	68645961	2	+	27260156	RDES	viability	CAGCGACTATGATATGCCTTTGG	PROKR1	ENSG00000169618	-0.1709403928387183	[252]	[212,322,254,233]	-3	hSpCas9	negative selection	8474791
68645985	68646008	2	-	27260156	RDES	viability	CTTGGCAGCAAAGAACGTCCTGG	PROKR1	ENSG00000169618	-0.04037736485779986	[447]	[386,434,493,740]	0	hSpCas9	negative selection	8539048
68655269	68655292	2	-	27260156	RDES	viability	GGGCGCCCAGCATAGCACGTAGG	PROKR1	ENSG00000169618	-0.4420317364408297	[158]	[88,139,187,127]	-6	hSpCas9	negative selection	8539049
68654945	68654968	2	-	27260156	RDES	viability	GATGGACACCGTCCACACCAAGG	PROKR1	ENSG00000169618	0.14801483920467012	[608]	[567,715,750,1154]	2	hSpCas9	negative selection	8539050
68655305	68655328	2	-	27260156	PC3	viability	GGGGAAGAAGTCGCGCACGATGG	PROKR1	ENSG00000169618	-0.19150079983681678	[77]	[56,95,71,41]	-4	hSpCas9	negative selection	8596040
68655108	68655131	2	+	27260156	PC3	viability	CATAGAATTCGTGGGCCCCGTGG	PROKR1	ENSG00000169618	0.19250954708006873	[268]	[246,334,238,366]	4	hSpCas9	negative selection	8596041
68645938	68645961	2	+	27260156	PC3	viability	CAGCGACTATGATATGCCTTTGG	PROKR1	ENSG00000169618	-0.3174682353527125	[252]	[122,105,520,205]	-6	hSpCas9	negative selection	8596042
68645985	68646008	2	-	27260156	PC3	viability	CTTGGCAGCAAAGAACGTCCTGG	PROKR1	ENSG00000169618	-0.22917968708561676	[447]	[273,306,546,473]	-5	hSpCas9	negative selection	8660299
68655269	68655292	2	-	27260156	PC3	viability	GGGCGCCCAGCATAGCACGTAGG	PROKR1	ENSG00000169618	-0.6899218759806471	[158]	[54,115,148,101]	-9	hSpCas9	negative selection	8660300
68654945	68654968	2	-	27260156	PC3	viability	GATGGACACCGTCCACACCAAGG	PROKR1	ENSG00000169618	0.12687210785107333	[608]	[323,737,1252,657]	3	hSpCas9	negative selection	8660301
68655305	68655328	2	-	27260156	PATU8988T	viability	GGGGAAGAAGTCGCGCACGATGG	PROKR1	ENSG00000169618	0.10988132645133986	[77]	[103,46,118,48]	2	hSpCas9	negative selection	8717291
68655108	68655131	2	+	27260156	PATU8988T	viability	CATAGAATTCGTGGGCCCCGTGG	PROKR1	ENSG00000169618	0.24117944103509348	[268]	[166,177,406,476]	4	hSpCas9	negative selection	8717292
68645938	68645961	2	+	27260156	PATU8988T	viability	CAGCGACTATGATATGCCTTTGG	PROKR1	ENSG00000169618	0.1567909103789631	[252]	[317,211,323,225]	2	hSpCas9	negative selection	8717293
68645985	68646008	2	-	27260156	PATU8988T	viability	CTTGGCAGCAAAGAACGTCCTGG	PROKR1	ENSG00000169618	-0.3058969017773344	[447]	[337,333,325,405]	-5	hSpCas9	negative selection	8781550
68655269	68655292	2	-	27260156	PATU8988T	viability	GGGCGCCCAGCATAGCACGTAGG	PROKR1	ENSG00000169618	-0.5404244012194455	[158]	[33,114,182,88]	-7	hSpCas9	negative selection	8781551
68654945	68654968	2	-	27260156	PATU8988T	viability	GATGGACACCGTCCACACCAAGG	PROKR1	ENSG00000169618	-0.21341724908305723	[608]	[583,320,680,416]	-4	hSpCas9	negative selection	8781552
68655305	68655328	2	-	27260156	T47D	viability	GGGGAAGAAGTCGCGCACGATGG	PROKR1	ENSG00000169618	0.1780664079411145	[77]	[113,92,83,121]	4	hSpCas9	negative selection	8838542
68655108	68655131	2	+	27260156	T47D	viability	CATAGAATTCGTGGGCCCCGTGG	PROKR1	ENSG00000169618	0.2702104101289001	[268]	[410,321,408,373]	6	hSpCas9	negative selection	8838543
68645938	68645961	2	+	27260156	T47D	viability	CAGCGACTATGATATGCCTTTGG	PROKR1	ENSG00000169618	-0.11394629305048021	[252]	[222,273,323,266]	-3	hSpCas9	negative selection	8838544
68645985	68646008	2	-	27260156	T47D	viability	CTTGGCAGCAAAGAACGTCCTGG	PROKR1	ENSG00000169618	0.10060002758864656	[447]	[539,546,606,543]	2	hSpCas9	negative selection	8902801
68655269	68655292	2	-	27260156	T47D	viability	GGGCGCCCAGCATAGCACGTAGG	PROKR1	ENSG00000169618	-0.017766588378494097	[158]	[156,165,215,193]	0	hSpCas9	negative selection	8902802
68654945	68654968	2	-	27260156	T47D	viability	GATGGACACCGTCCACACCAAGG	PROKR1	ENSG00000169618	-0.09206958783100322	[608]	[710,588,631,739]	-2	hSpCas9	negative selection	8902803
68655305	68655328	2	-	27260156	SU8686	viability	GGGGAAGAAGTCGCGCACGATGG	PROKR1	ENSG00000169618	-0.09686655640442243	[77]	[53,61,104,71]	-2	hSpCas9	negative selection	8959793
68655108	68655131	2	+	27260156	SU8686	viability	CATAGAATTCGTGGGCCCCGTGG	PROKR1	ENSG00000169618	0.6964715548362473	[268]	[389,423,336,605]	9	hSpCas9	negative selection	8959794
68645938	68645961	2	+	27260156	SU8686	viability	CAGCGACTATGATATGCCTTTGG	PROKR1	ENSG00000169618	-0.41263798021687514	[252]	[189,192,243,113]	-6	hSpCas9	negative selection	8959795
68645985	68646008	2	-	27260156	SU8686	viability	CTTGGCAGCAAAGAACGTCCTGG	PROKR1	ENSG00000169618	0.16152276556308365	[447]	[445,451,509,604]	2	hSpCas9	negative selection	9024052
68655269	68655292	2	-	27260156	SU8686	viability	GGGCGCCCAGCATAGCACGTAGG	PROKR1	ENSG00000169618	-0.12686254206267256	[158]	[141,103,175,163]	-2	hSpCas9	negative selection	9024053
68654945	68654968	2	-	27260156	SU8686	viability	GATGGACACCGTCCACACCAAGG	PROKR1	ENSG00000169618	-0.05726093272308652	[608]	[523,475,561,811]	-1	hSpCas9	negative selection	9024054
68655305	68655328	2	-	27260156	SKES1	viability	GGGGAAGAAGTCGCGCACGATGG	PROKR1	ENSG00000169618	-0.7187248804651283	[77]	[52,75,34,30]	-9	hSpCas9	negative selection	9081044
68655108	68655131	2	+	27260156	SKES1	viability	CATAGAATTCGTGGGCCCCGTGG	PROKR1	ENSG00000169618	0.0022859508675874274	[268]	[381,283,257,176]	0	hSpCas9	negative selection	9081045
68645938	68645961	2	+	27260156	SKES1	viability	CAGCGACTATGATATGCCTTTGG	PROKR1	ENSG00000169618	-0.28714832271880386	[252]	[380,134,172,157]	-6	hSpCas9	negative selection	9081046
68645985	68646008	2	-	27260156	SKES1	viability	CTTGGCAGCAAAGAACGTCCTGG	PROKR1	ENSG00000169618	0.16407865097633778	[447]	[555,459,498,486]	3	hSpCas9	negative selection	9145303
68655269	68655292	2	-	27260156	SKES1	viability	GGGCGCCCAGCATAGCACGTAGG	PROKR1	ENSG00000169618	-0.6753163006926237	[158]	[150,140,64,56]	-9	hSpCas9	negative selection	9145304
68654945	68654968	2	-	27260156	SKES1	viability	GATGGACACCGTCCACACCAAGG	PROKR1	ENSG00000169618	-0.17351209078162974	[608]	[601,552,462,541]	-4	hSpCas9	negative selection	9145305
68655305	68655328	2	-	27260156	TOV112D	viability	GGGGAAGAAGTCGCGCACGATGG	PROKR1	ENSG00000169618	-0.1942947663181167	[77]	[33,54,78,97]	-4	hSpCas9	negative selection	9202295
68655108	68655131	2	+	27260156	TOV112D	viability	CATAGAATTCGTGGGCCCCGTGG	PROKR1	ENSG00000169618	-0.14775525171965664	[268]	[265,300,304,119]	-3	hSpCas9	negative selection	9202296
68645938	68645961	2	+	27260156	TOV112D	viability	CAGCGACTATGATATGCCTTTGG	PROKR1	ENSG00000169618	-0.31411114265903883	[252]	[210,233,211,166]	-6	hSpCas9	negative selection	9202297
68645985	68646008	2	-	27260156	TOV112D	viability	CTTGGCAGCAAAGAACGTCCTGG	PROKR1	ENSG00000169618	0.4625621760207156	[447]	[608,698,483,696]	8	hSpCas9	negative selection	9266554
68655269	68655292	2	-	27260156	TOV112D	viability	GGGCGCCCAGCATAGCACGTAGG	PROKR1	ENSG00000169618	-0.6453835975148432	[158]	[194,112,55,54]	-8	hSpCas9	negative selection	9266555
68654945	68654968	2	-	27260156	TOV112D	viability	GATGGACACCGTCCACACCAAGG	PROKR1	ENSG00000169618	0.024016844929536596	[608]	[741,675,548,538]	0	hSpCas9	negative selection	9266556
68655305	68655328	2	-	27260156	TC71	viability	GGGGAAGAAGTCGCGCACGATGG	PROKR1	ENSG00000169618	0.18512414680496692	[77]	[104,90,110,70]	4	hSpCas9	negative selection	9323546
68655108	68655131	2	+	27260156	TC71	viability	CATAGAATTCGTGGGCCCCGTGG	PROKR1	ENSG00000169618	0.2968689403717881	[268]	[412,372,248,385]	7	hSpCas9	negative selection	9323547
68645938	68645961	2	+	27260156	TC71	viability	CAGCGACTATGATATGCCTTTGG	PROKR1	ENSG00000169618	-0.36408766361738687	[252]	[246,194,186,213]	-7	hSpCas9	negative selection	9323548
68645985	68646008	2	-	27260156	TC71	viability	CTTGGCAGCAAAGAACGTCCTGG	PROKR1	ENSG00000169618	0.11711315531373781	[447]	[596,522,414,551]	3	hSpCas9	negative selection	9387805
68655269	68655292	2	-	27260156	TC71	viability	GGGCGCCCAGCATAGCACGTAGG	PROKR1	ENSG00000169618	-0.07758864957180256	[158]	[149,190,142,162]	-2	hSpCas9	negative selection	9387806
68654945	68654968	2	-	27260156	TC71	viability	GATGGACACCGTCCACACCAAGG	PROKR1	ENSG00000169618	-0.05432839987258864	[608]	[652,626,604,629]	-1	hSpCas9	negative selection	9387807
68655305	68655328	2	-	27260156	TC32	viability	GGGGAAGAAGTCGCGCACGATGG	PROKR1	ENSG00000169618	-0.14436604119496987	[77]	[103,62,47,36]	-3	hSpCas9	negative selection	9444797
68655108	68655131	2	+	27260156	TC32	viability	CATAGAATTCGTGGGCCCCGTGG	PROKR1	ENSG00000169618	0.12632010468383725	[268]	[263,192,379,302]	2	hSpCas9	negative selection	9444798
68645938	68645961	2	+	27260156	TC32	viability	CAGCGACTATGATATGCCTTTGG	PROKR1	ENSG00000169618	-0.36093212706825284	[252]	[125,111,277,270]	-6	hSpCas9	negative selection	9444799
68645985	68646008	2	-	27260156	TC32	viability	CTTGGCAGCAAAGAACGTCCTGG	PROKR1	ENSG00000169618	-0.22013092987269856	[447]	[402,138,498,495]	-4	hSpCas9	negative selection	9509056
68655269	68655292	2	-	27260156	TC32	viability	GGGCGCCCAGCATAGCACGTAGG	PROKR1	ENSG00000169618	-0.25835697325787765	[158]	[132,46,139,208]	-5	hSpCas9	negative selection	9509057
68654945	68654968	2	-	27260156	TC32	viability	GATGGACACCGTCCACACCAAGG	PROKR1	ENSG00000169618	-0.07239566613328818	[608]	[632,361,625,597]	-1	hSpCas9	negative selection	9509058
68646007	68646030	2	+	27869803	HPAFII	viability after 27 days	GATTGTCATTGGGATGGCCCTGG	PROKR1	ENSG00000169618	1.8440157377365722	[20]	[13,60,NaN]	9	hSpCas9	negative selection	9575470
68646079	68646102	2	-	27869803	HPAFII	viability after 27 days	GCAGTTTCTTGTAGCGGACCAGG	PROKR1	ENSG00000169618	0.6019400511270054	[282]	[287,173,NaN]	5	hSpCas9	negative selection	9575471
68646291	68646314	2	-	27869803	HPAFII	viability after 27 days	CACTCACCTGTCAATGGCGATGG	PROKR1	ENSG00000169618	-0.5746642478005668	[341]	[225,32,NaN]	-4	hSpCas9	negative selection	9575472
68654914	68654937	2	+	27869803	HPAFII	viability after 27 days	ATGAAGTGCCAAACAGCCACTGG	PROKR1	ENSG00000169618	0.4707227794022326	[139]	[71,126,NaN]	4	hSpCas9	negative selection	9575473
68654979	68655002	2	-	27869803	HPAFII	viability after 27 days	CGGTGGTGAAGTAGGCGGAAGGG	PROKR1	ENSG00000169618	0.355399490501076	[709]	[494,462,NaN]	3	hSpCas9	negative selection	9575474
68655471	68655494	2	-	27869803	HPAFII	viability after 27 days	CATTGTAAGAAGCCTTCCAGTGG	PROKR1	ENSG00000169618	-1.245942292175213	[218]	[101,3,NaN]	-7	hSpCas9	negative selection	9575475
68646007	68646030	2	+	27869803	HPAFII	viability after 15 days	GATTGTCATTGGGATGGCCCTGG	PROKR1	ENSG00000169618	0.8885416105551145	[20]	[34,45,NaN]	8	hSpCas9	negative selection	9657919
68646079	68646102	2	-	27869803	HPAFII	viability after 15 days	GCAGTTTCTTGTAGCGGACCAGG	PROKR1	ENSG00000169618	0.7210870336028458	[282]	[665,398,NaN]	7	hSpCas9	negative selection	9657920
68646291	68646314	2	-	27869803	HPAFII	viability after 15 days	CACTCACCTGTCAATGGCGATGG	PROKR1	ENSG00000169618	-0.2975353085380362	[341]	[578,124,NaN]	-3	hSpCas9	negative selection	9657921
68654914	68654937	2	+	27869803	HPAFII	viability after 15 days	ATGAAGTGCCAAACAGCCACTGG	PROKR1	ENSG00000169618	-0.5533047937447351	[139]	[104,100,NaN]	-5	hSpCas9	negative selection	9657922
68654979	68655002	2	-	27869803	HPAFII	viability after 15 days	CGGTGGTGAAGTAGGCGGAAGGG	PROKR1	ENSG00000169618	0.42689966876248064	[709]	[1314,845,NaN]	5	hSpCas9	negative selection	9657923
68655471	68655494	2	-	27869803	HPAFII	viability after 15 days	CATTGTAAGAAGCCTTCCAGTGG	PROKR1	ENSG00000169618	-0.8793588728218193	[218]	[270,38,NaN]	-7	hSpCas9	negative selection	9657924
68646007	68646030	2	+	27869803	ASPC1	viability after 36 days	GATTGTCATTGGGATGGCCCTGG	PROKR1	ENSG00000169618	1.6057239993925723	[97]	[17,115,153]	9	hSpCas9	negative selection	9740368
68646079	68646102	2	-	27869803	ASPC1	viability after 36 days	GCAGTTTCTTGTAGCGGACCAGG	PROKR1	ENSG00000169618	0.1907088345767874	[705]	[427,345,123]	2	hSpCas9	negative selection	9740369
68646291	68646314	2	-	27869803	ASPC1	viability after 36 days	CACTCACCTGTCAATGGCGATGG	PROKR1	ENSG00000169618	-0.3048201768735316	[896]	[393,346,77]	-3	hSpCas9	negative selection	9740370
68654914	68654937	2	+	27869803	ASPC1	viability after 36 days	ATGAAGTGCCAAACAGCCACTGG	PROKR1	ENSG00000169618	0.7237938781032512	[369]	[327,140,187]	7	hSpCas9	negative selection	9740371
68654979	68655002	2	-	27869803	ASPC1	viability after 36 days	CGGTGGTGAAGTAGGCGGAAGGG	PROKR1	ENSG00000169618	0.016262069304820548	[1505]	[282,1010,319]	0	hSpCas9	negative selection	9740372
68655471	68655494	2	-	27869803	ASPC1	viability after 36 days	CATTGTAAGAAGCCTTCCAGTGG	PROKR1	ENSG00000169618	0.8081155085882711	[446]	[211,396,214]	7	hSpCas9	negative selection	9740373
68646007	68646030	2	+	27869803	PATU8988S	viability after 35 days	GATTGTCATTGGGATGGCCCTGG	PROKR1	ENSG00000169618	1.2020950039655856	[60]	[66,45,NaN]	9	hSpCas9	negative selection	9822817
68646079	68646102	2	-	27869803	PATU8988S	viability after 35 days	GCAGTTTCTTGTAGCGGACCAGG	PROKR1	ENSG00000169618	0.48589345656562144	[656]	[400,339,NaN]	5	hSpCas9	negative selection	9822818
68646291	68646314	2	-	27869803	PATU8988S	viability after 35 days	CACTCACCTGTCAATGGCGATGG	PROKR1	ENSG00000169618	0.19593167689029745	[814]	[370,380,NaN]	2	hSpCas9	negative selection	9822819
68654914	68654937	2	+	27869803	PATU8988S	viability after 35 days	ATGAAGTGCCAAACAGCCACTGG	PROKR1	ENSG00000169618	-1.5113092928247012	[307]	[49,36,NaN]	-8	hSpCas9	negative selection	9822820
68654979	68655002	2	-	27869803	PATU8988S	viability after 35 days	CGGTGGTGAAGTAGGCGGAAGGG	PROKR1	ENSG00000169618	0.2935204626212933	[1262]	[598,647,NaN]	3	hSpCas9	negative selection	9822821
68655471	68655494	2	-	27869803	PATU8988S	viability after 35 days	CATTGTAAGAAGCCTTCCAGTGG	PROKR1	ENSG00000169618	-0.20642635468932857	[347]	[108,133,NaN]	-2	hSpCas9	negative selection	9822822
68646007	68646030	2	+	27869803	PATU8988S	viability after 31 days	GATTGTCATTGGGATGGCCCTGG	PROKR1	ENSG00000169618	0.7962801751499251	[60]	[43,39,NaN]	8	hSpCas9	negative selection	9905266
68646079	68646102	2	-	27869803	PATU8988S	viability after 31 days	GCAGTTTCTTGTAGCGGACCAGG	PROKR1	ENSG00000169618	0.39870550933848525	[656]	[380,299,NaN]	5	hSpCas9	negative selection	9905267
68646291	68646314	2	-	27869803	PATU8988S	viability after 31 days	CACTCACCTGTCAATGGCGATGG	PROKR1	ENSG00000169618	0.35324348667974925	[814]	[481,329,NaN]	4	hSpCas9	negative selection	9905268
68654914	68654937	2	+	27869803	PATU8988S	viability after 31 days	ATGAAGTGCCAAACAGCCACTGG	PROKR1	ENSG00000169618	-1.255566753838072	[307]	[39,65,NaN]	-8	hSpCas9	negative selection	9905269
68654979	68655002	2	-	27869803	PATU8988S	viability after 31 days	CGGTGGTGAAGTAGGCGGAAGGG	PROKR1	ENSG00000169618	0.3918545774464217	[1262]	[563,783,NaN]	5	hSpCas9	negative selection	9905270
68655471	68655494	2	-	27869803	PATU8988S	viability after 31 days	CATTGTAAGAAGCCTTCCAGTGG	PROKR1	ENSG00000169618	-0.044831532333709845	[347]	[119,152,NaN]	0	hSpCas9	negative selection	9905271
68646007	68646030	2	+	27869803	HPAFII	viability after 35 days	GATTGTCATTGGGATGGCCCTGG	PROKR1	ENSG00000169618	2.2037825581305746	[20]	[0,102,NaN]	9	hSpCas9	negative selection	9987715
68646079	68646102	2	-	27869803	HPAFII	viability after 35 days	GCAGTTTCTTGTAGCGGACCAGG	PROKR1	ENSG00000169618	0.5305591044881518	[282]	[221,189,NaN]	3	hSpCas9	negative selection	9987716
68646291	68646314	2	-	27869803	HPAFII	viability after 35 days	CACTCACCTGTCAATGGCGATGG	PROKR1	ENSG00000169618	-0.1206591597616467	[341]	[178,136,NaN]	0	hSpCas9	negative selection	9987717
68654914	68654937	2	+	27869803	HPAFII	viability after 35 days	ATGAAGTGCCAAACAGCCACTGG	PROKR1	ENSG00000169618	-0.052621233534762224	[139]	[33,106,NaN]	0	hSpCas9	negative selection	9987718
68654979	68655002	2	-	27869803	HPAFII	viability after 35 days	CGGTGGTGAAGTAGGCGGAAGGG	PROKR1	ENSG00000169618	0.8868948127598615	[709]	[579,759,NaN]	6	hSpCas9	negative selection	9987719
68655471	68655494	2	-	27869803	HPAFII	viability after 35 days	CATTGTAAGAAGCCTTCCAGTGG	PROKR1	ENSG00000169618	-0.324030197695623	[218]	[160,6,NaN]	-2	hSpCas9	negative selection	9987720
68646007	68646030	2	+	27869803	HPAFII	viability after 31 days	GATTGTCATTGGGATGGCCCTGG	PROKR1	ENSG00000169618	2.226716415991855	[20]	[2,111,NaN]	9	hSpCas9	negative selection	10070164
68646079	68646102	2	-	27869803	HPAFII	viability after 31 days	GCAGTTTCTTGTAGCGGACCAGG	PROKR1	ENSG00000169618	0.2901654100686623	[282]	[142,249,NaN]	2	hSpCas9	negative selection	10070165
68646291	68646314	2	-	27869803	HPAFII	viability after 31 days	CACTCACCTGTCAATGGCGATGG	PROKR1	ENSG00000169618	-1.1203732093638696	[341]	[116,56,NaN]	-6	hSpCas9	negative selection	10070166
68654914	68654937	2	+	27869803	HPAFII	viability after 31 days	ATGAAGTGCCAAACAGCCACTGG	PROKR1	ENSG00000169618	0.08680483522677551	[139]	[70,96,NaN]	0	hSpCas9	negative selection	10070167
68654979	68655002	2	-	27869803	HPAFII	viability after 31 days	CGGTGGTGAAGTAGGCGGAAGGG	PROKR1	ENSG00000169618	0.4005170153128139	[709]	[513,538,NaN]	3	hSpCas9	negative selection	10070168
68655471	68655494	2	-	27869803	HPAFII	viability after 31 days	CATTGTAAGAAGCCTTCCAGTGG	PROKR1	ENSG00000169618	-0.6820088495966117	[218]	[145,0,NaN]	-4	hSpCas9	negative selection	10070169
68645829	68645852	2	-	28162770	P31FUJ	viability	GTCATCCATGAACCCCATGGTGG	PROKR1	ENSG00000169618	0.6894755001611035	[285]	[541]	7	hSpCas9	negative selection	10217479
68646276	68646299	2	-	28162770	P31FUJ	viability	GGCGATGGCCAGCAGGGCATTGG	PROKR1	ENSG00000169618	-0.08607405301000282	[410]	[454]	-1	hSpCas9	negative selection	10217480
68645894	68645917	2	-	28162770	P31FUJ	viability	GAAGTGGCATGGGCTCCATGAGG	PROKR1	ENSG00000169618	-0.37840752666127797	[374]	[338]	-3	hSpCas9	negative selection	10217481
68645910	68645933	2	-	28162770	P31FUJ	viability	GAAGTTGAATGGGAAGGAAGTGG	PROKR1	ENSG00000169618	0.13975196354295172	[111]	[144]	1	hSpCas9	negative selection	10217482
68646135	68646158	2	-	28162770	P31FUJ	viability	GGCCACCAGGAAGTCAGAGATGG	PROKR1	ENSG00000169618	0.37385536740609654	[175]	[267]	4	hSpCas9	negative selection	10217483
68645856	68645879	2	-	28162770	P31FUJ	viability	GAAGCTGGTGGAAGTGTTGGTGG	PROKR1	ENSG00000169618	0.29950134703421427	[185]	[268]	3	hSpCas9	negative selection	10217484
68646024	68646047	2	-	28162770	P31FUJ	viability	GACCAGCATGATGCCCACCAGGG	PROKR1	ENSG00000169618	0.07473755829987017	[1047]	[1296]	0	hSpCas9	negative selection	10217485
68646226	68646249	2	-	28162770	P31FUJ	viability	GGTAGTTGACAGAGGTGCACAGG	PROKR1	ENSG00000169618	0.5112267822743963	[162]	[272]	6	hSpCas9	negative selection	10217486
68646247	68646270	2	-	28162770	P31FUJ	viability	CATAGAGAGAGACAGTGCGCAGG	PROKR1	ENSG00000169618	-0.15905386443306604	[285]	[300]	-1	hSpCas9	negative selection	10217487
68646160	68646183	2	+	28162770	P31FUJ	viability	TGTCTGCTGCCCCTTTGAGATGG	PROKR1	ENSG00000169618	0.30413878144383405	[223]	[324]	3	hSpCas9	negative selection	10217488
68645829	68645852	2	-	28162770	TF1	viability	GTCATCCATGAACCCCATGGTGG	PROKR1	ENSG00000169618	NaN	[NaN]	[323]	1	hSpCas9	negative selection	10386845
68646276	68646299	2	-	28162770	TF1	viability	GGCGATGGCCAGCAGGGCATTGG	PROKR1	ENSG00000169618	NaN	[NaN]	[393]	1	hSpCas9	negative selection	10386846
68645894	68645917	2	-	28162770	TF1	viability	GAAGTGGCATGGGCTCCATGAGG	PROKR1	ENSG00000169618	NaN	[NaN]	[147]	1	hSpCas9	negative selection	10386847
68645910	68645933	2	-	28162770	TF1	viability	GAAGTTGAATGGGAAGGAAGTGG	PROKR1	ENSG00000169618	NaN	[NaN]	[14]	1	hSpCas9	negative selection	10386848
68646135	68646158	2	-	28162770	TF1	viability	GGCCACCAGGAAGTCAGAGATGG	PROKR1	ENSG00000169618	NaN	[NaN]	[130]	1	hSpCas9	negative selection	10386849
68645856	68645879	2	-	28162770	TF1	viability	GAAGCTGGTGGAAGTGTTGGTGG	PROKR1	ENSG00000169618	NaN	[NaN]	[173]	1	hSpCas9	negative selection	10386850
68646024	68646047	2	-	28162770	TF1	viability	GACCAGCATGATGCCCACCAGGG	PROKR1	ENSG00000169618	NaN	[NaN]	[969]	1	hSpCas9	negative selection	10386851
68646226	68646249	2	-	28162770	TF1	viability	GGTAGTTGACAGAGGTGCACAGG	PROKR1	ENSG00000169618	NaN	[NaN]	[66]	1	hSpCas9	negative selection	10386852
68646247	68646270	2	-	28162770	TF1	viability	CATAGAGAGAGACAGTGCGCAGG	PROKR1	ENSG00000169618	NaN	[NaN]	[176]	1	hSpCas9	negative selection	10386853
68646160	68646183	2	+	28162770	TF1	viability	TGTCTGCTGCCCCTTTGAGATGG	PROKR1	ENSG00000169618	NaN	[NaN]	[167]	1	hSpCas9	negative selection	10386854
68645829	68645852	2	-	28162770	SKM1	viability	GTCATCCATGAACCCCATGGTGG	PROKR1	ENSG00000169618	0.16987042109459427	[88]	[176]	1	hSpCas9	negative selection	10556211
68646276	68646299	2	-	28162770	SKM1	viability	GGCGATGGCCAGCAGGGCATTGG	PROKR1	ENSG00000169618	0.004849399661395637	[83]	[148]	0	hSpCas9	negative selection	10556212
68645894	68645917	2	-	28162770	SKM1	viability	GAAGTGGCATGGGCTCCATGAGG	PROKR1	ENSG00000169618	0.28729694446880605	[107]	[232]	3	hSpCas9	negative selection	10556213
68645910	68645933	2	-	28162770	SKM1	viability	GAAGTTGAATGGGAAGGAAGTGG	PROKR1	ENSG00000169618	-1.348070509689593	[35]	[24]	-7	hSpCas9	negative selection	10556214
68646135	68646158	2	-	28162770	SKM1	viability	GGCCACCAGGAAGTCAGAGATGG	PROKR1	ENSG00000169618	0.8832550364168625	[45]	[149]	8	hSpCas9	negative selection	10556215
68645856	68645879	2	-	28162770	SKM1	viability	GAAGCTGGTGGAAGTGTTGGTGG	PROKR1	ENSG00000169618	0.9170839480185702	[67]	[226]	8	hSpCas9	negative selection	10556216
68646024	68646047	2	-	28162770	SKM1	viability	GACCAGCATGATGCCCACCAGGG	PROKR1	ENSG00000169618	0.782500989094796	[219]	[668]	7	hSpCas9	negative selection	10556217
68646226	68646249	2	-	28162770	SKM1	viability	GGTAGTTGACAGAGGTGCACAGG	PROKR1	ENSG00000169618	-0.3713402890124403	[29]	[40]	-3	hSpCas9	negative selection	10556218
68646247	68646270	2	-	28162770	SKM1	viability	CATAGAGAGAGACAGTGCGCAGG	PROKR1	ENSG00000169618	0.6232360390325373	[64]	[176]	6	hSpCas9	negative selection	10556219
68646160	68646183	2	+	28162770	SKM1	viability	TGTCTGCTGCCCCTTTGAGATGG	PROKR1	ENSG00000169618	0.13145571604096423	[62]	[121]	1	hSpCas9	negative selection	10556220
68645829	68645852	2	-	28162770	SKM1	viability	GTCATCCATGAACCCCATGGTGG	PROKR1	ENSG00000169618	0.16987042109459427	[88]	[176]	1	hSpCas9	negative selection	10725577
68646276	68646299	2	-	28162770	SKM1	viability	GGCGATGGCCAGCAGGGCATTGG	PROKR1	ENSG00000169618	0.004849399661395637	[83]	[148]	0	hSpCas9	negative selection	10725578
68645894	68645917	2	-	28162770	SKM1	viability	GAAGTGGCATGGGCTCCATGAGG	PROKR1	ENSG00000169618	0.28729694446880605	[107]	[232]	3	hSpCas9	negative selection	10725579
68645910	68645933	2	-	28162770	SKM1	viability	GAAGTTGAATGGGAAGGAAGTGG	PROKR1	ENSG00000169618	-1.348070509689593	[35]	[24]	-7	hSpCas9	negative selection	10725580
68646135	68646158	2	-	28162770	SKM1	viability	GGCCACCAGGAAGTCAGAGATGG	PROKR1	ENSG00000169618	0.8832550364168625	[45]	[149]	8	hSpCas9	negative selection	10725581
68645856	68645879	2	-	28162770	SKM1	viability	GAAGCTGGTGGAAGTGTTGGTGG	PROKR1	ENSG00000169618	0.9170839480185702	[67]	[226]	8	hSpCas9	negative selection	10725582
68646024	68646047	2	-	28162770	SKM1	viability	GACCAGCATGATGCCCACCAGGG	PROKR1	ENSG00000169618	0.782500989094796	[219]	[668]	7	hSpCas9	negative selection	10725583
68646226	68646249	2	-	28162770	SKM1	viability	GGTAGTTGACAGAGGTGCACAGG	PROKR1	ENSG00000169618	-0.3713402890124403	[29]	[40]	-3	hSpCas9	negative selection	10725584
68646247	68646270	2	-	28162770	SKM1	viability	CATAGAGAGAGACAGTGCGCAGG	PROKR1	ENSG00000169618	0.6232360390325373	[64]	[176]	6	hSpCas9	negative selection	10725585
68646160	68646183	2	+	28162770	SKM1	viability	TGTCTGCTGCCCCTTTGAGATGG	PROKR1	ENSG00000169618	0.13145571604096423	[62]	[121]	1	hSpCas9	negative selection	10725586
68645829	68645852	2	-	28162770	PL21	viability	GTCATCCATGAACCCCATGGTGG	PROKR1	ENSG00000169618	0.4171688510586753	[307]	[178]	3	hSpCas9	negative selection	10894943
68646276	68646299	2	-	28162770	PL21	viability	GGCGATGGCCAGCAGGGCATTGG	PROKR1	ENSG00000169618	-0.6721048383123072	[215]	[58]	-5	hSpCas9	negative selection	10894944
68645894	68645917	2	-	28162770	PL21	viability	GAAGTGGCATGGGCTCCATGAGG	PROKR1	ENSG00000169618	0.2811761865802267	[449]	[237]	2	hSpCas9	negative selection	10894945
68645910	68645933	2	-	28162770	PL21	viability	GAAGTTGAATGGGAAGGAAGTGG	PROKR1	ENSG00000169618	-0.6016342753049844	[128]	[36]	-4	hSpCas9	negative selection	10894946
68646135	68646158	2	-	28162770	PL21	viability	GGCCACCAGGAAGTCAGAGATGG	PROKR1	ENSG00000169618	1.3281472268653916	[193]	[211]	9	hSpCas9	negative selection	10894947
68645856	68645879	2	-	28162770	PL21	viability	GAAGCTGGTGGAAGTGTTGGTGG	PROKR1	ENSG00000169618	0.11976619802530007	[202]	[95]	1	hSpCas9	negative selection	10894948
68646024	68646047	2	-	28162770	PL21	viability	GACCAGCATGATGCCCACCAGGG	PROKR1	ENSG00000169618	0.4610223494680652	[670]	[401]	4	hSpCas9	negative selection	10894949
68646226	68646249	2	-	28162770	PL21	viability	GGTAGTTGACAGAGGTGCACAGG	PROKR1	ENSG00000169618	0.10703021009783875	[95]	[44]	0	hSpCas9	negative selection	10894950
68646247	68646270	2	-	28162770	PL21	viability	CATAGAGAGAGACAGTGCGCAGG	PROKR1	ENSG00000169618	-1.4971258558566283	[226]	[34]	-7	hSpCas9	negative selection	10894951
68646160	68646183	2	+	28162770	PL21	viability	TGTCTGCTGCCCCTTTGAGATGG	PROKR1	ENSG00000169618	0.6627665722864242	[163]	[112]	6	hSpCas9	negative selection	10894952
68645829	68645852	2	-	28162770	P31FUJ	viability	GTCATCCATGAACCCCATGGTGG	PROKR1	ENSG00000169618	0.6894755001611035	[285]	[541]	7	hSpCas9	negative selection	11064309
68646276	68646299	2	-	28162770	P31FUJ	viability	GGCGATGGCCAGCAGGGCATTGG	PROKR1	ENSG00000169618	-0.08607405301000282	[410]	[454]	-1	hSpCas9	negative selection	11064310
68645894	68645917	2	-	28162770	P31FUJ	viability	GAAGTGGCATGGGCTCCATGAGG	PROKR1	ENSG00000169618	-0.37840752666127797	[374]	[338]	-3	hSpCas9	negative selection	11064311
68645910	68645933	2	-	28162770	P31FUJ	viability	GAAGTTGAATGGGAAGGAAGTGG	PROKR1	ENSG00000169618	0.13975196354295172	[111]	[144]	1	hSpCas9	negative selection	11064312
68646135	68646158	2	-	28162770	P31FUJ	viability	GGCCACCAGGAAGTCAGAGATGG	PROKR1	ENSG00000169618	0.37385536740609654	[175]	[267]	4	hSpCas9	negative selection	11064313
68645856	68645879	2	-	28162770	P31FUJ	viability	GAAGCTGGTGGAAGTGTTGGTGG	PROKR1	ENSG00000169618	0.29950134703421427	[185]	[268]	3	hSpCas9	negative selection	11064314
68646024	68646047	2	-	28162770	P31FUJ	viability	GACCAGCATGATGCCCACCAGGG	PROKR1	ENSG00000169618	0.07473755829987017	[1047]	[1296]	0	hSpCas9	negative selection	11064315
68646226	68646249	2	-	28162770	P31FUJ	viability	GGTAGTTGACAGAGGTGCACAGG	PROKR1	ENSG00000169618	0.5112267822743963	[162]	[272]	6	hSpCas9	negative selection	11064316
68646247	68646270	2	-	28162770	P31FUJ	viability	CATAGAGAGAGACAGTGCGCAGG	PROKR1	ENSG00000169618	-0.15905386443306604	[285]	[300]	-1	hSpCas9	negative selection	11064317
68646160	68646183	2	+	28162770	P31FUJ	viability	TGTCTGCTGCCCCTTTGAGATGG	PROKR1	ENSG00000169618	0.30413878144383405	[223]	[324]	3	hSpCas9	negative selection	11064318
68645829	68645852	2	-	28162770	OCIAML5	viability	GTCATCCATGAACCCCATGGTGG	PROKR1	ENSG00000169618	-0.047082553269139904	[173]	[303]	0	hSpCas9	negative selection	11233675
68646276	68646299	2	-	28162770	OCIAML5	viability	GGCGATGGCCAGCAGGGCATTGG	PROKR1	ENSG00000169618	0.7979909580790441	[129]	[407]	7	hSpCas9	negative selection	11233676
68645894	68645917	2	-	28162770	OCIAML5	viability	GAAGTGGCATGGGCTCCATGAGG	PROKR1	ENSG00000169618	-1.2369840817665054	[315]	[241]	-6	hSpCas9	negative selection	11233677
68645910	68645933	2	-	28162770	OCIAML5	viability	GAAGTTGAATGGGAAGGAAGTGG	PROKR1	ENSG00000169618	-3.1558473190411	[78]	[15]	-9	hSpCas9	negative selection	11233678
68646135	68646158	2	-	28162770	OCIAML5	viability	GGCCACCAGGAAGTCAGAGATGG	PROKR1	ENSG00000169618	0.721924812036156	[87]	[261]	6	hSpCas9	negative selection	11233679
68645856	68645879	2	-	28162770	OCIAML5	viability	GAAGCTGGTGGAAGTGTTGGTGG	PROKR1	ENSG00000169618	0.4074956430629918	[103]	[248]	3	hSpCas9	negative selection	11233680
68646024	68646047	2	-	28162770	OCIAML5	viability	GACCAGCATGATGCCCACCAGGG	PROKR1	ENSG00000169618	0.30251046624487943	[503]	[1121]	2	hSpCas9	negative selection	11233681
68646226	68646249	2	-	28162770	OCIAML5	viability	GGTAGTTGACAGAGGTGCACAGG	PROKR1	ENSG00000169618	0.007335098963202391	[69]	[126]	0	hSpCas9	negative selection	11233682
68646247	68646270	2	-	28162770	OCIAML5	viability	CATAGAGAGAGACAGTGCGCAGG	PROKR1	ENSG00000169618	-0.16101681175314936	[165]	[267]	-1	hSpCas9	negative selection	11233683
68646160	68646183	2	+	28162770	OCIAML5	viability	TGTCTGCTGCCCCTTTGAGATGG	PROKR1	ENSG00000169618	0.8667516765919497	[119]	[394]	7	hSpCas9	negative selection	11233684
68645829	68645852	2	-	28162770	EOL1	viability	GTCATCCATGAACCCCATGGTGG	PROKR1	ENSG00000169618	-0.17202548812451834	[555]	[259]	-1	hSpCas9	negative selection	11403041
68646276	68646299	2	-	28162770	EOL1	viability	GGCGATGGCCAGCAGGGCATTGG	PROKR1	ENSG00000169618	3.2217079613089545	[328]	[1616]	9	hSpCas9	negative selection	11403042
68645894	68645917	2	-	28162770	EOL1	viability	GAAGTGGCATGGGCTCCATGAGG	PROKR1	ENSG00000169618	0.35479836479588545	[848]	[571]	3	hSpCas9	negative selection	11403043
68645910	68645933	2	-	28162770	EOL1	viability	GAAGTTGAATGGGAAGGAAGTGG	PROKR1	ENSG00000169618	-2.339792831763884	[220]	[22]	-8	hSpCas9	negative selection	11403044
68646135	68646158	2	-	28162770	EOL1	viability	GGCCACCAGGAAGTCAGAGATGG	PROKR1	ENSG00000169618	0.4371960674758004	[299]	[213]	4	hSpCas9	negative selection	11403045
68645856	68645879	2	-	28162770	EOL1	viability	GAAGCTGGTGGAAGTGTTGGTGG	PROKR1	ENSG00000169618	0.49988157109391385	[450]	[335]	4	hSpCas9	negative selection	11403046
68646024	68646047	2	-	28162770	EOL1	viability	GACCAGCATGATGCCCACCAGGG	PROKR1	ENSG00000169618	1.0980840265652259	[930]	[1049]	8	hSpCas9	negative selection	11403047
68646226	68646249	2	-	28162770	EOL1	viability	GGTAGTTGACAGAGGTGCACAGG	PROKR1	ENSG00000169618	0.4115965157647664	[126]	[88]	4	hSpCas9	negative selection	11403048
68646247	68646270	2	-	28162770	EOL1	viability	CATAGAGAGAGACAGTGCGCAGG	PROKR1	ENSG00000169618	-0.4243473709170973	[269]	[105]	-3	hSpCas9	negative selection	11403049
68646160	68646183	2	+	28162770	EOL1	viability	TGTCTGCTGCCCCTTTGAGATGG	PROKR1	ENSG00000169618	1.249027051987229	[225]	[282]	9	hSpCas9	negative selection	11403050
68645829	68645852	2	-	28162770	MOLM13	viability	GTCATCCATGAACCCCATGGTGG	PROKR1	ENSG00000169618	0.8707374718155088	[415]	[549]	6	hSpCas9	negative selection	11572407
68646276	68646299	2	-	28162770	MOLM13	viability	GGCGATGGCCAGCAGGGCATTGG	PROKR1	ENSG00000169618	0.20765360906345837	[308]	[257]	1	hSpCas9	negative selection	11572408
68645894	68645917	2	-	28162770	MOLM13	viability	GAAGTGGCATGGGCTCCATGAGG	PROKR1	ENSG00000169618	-1.4021420366532866	[540]	[147]	-6	hSpCas9	negative selection	11572409
68645910	68645933	2	-	28162770	MOLM13	viability	GAAGTTGAATGGGAAGGAAGTGG	PROKR1	ENSG00000169618	-0.6549673662409545	[195]	[89]	-4	hSpCas9	negative selection	11572410
68646135	68646158	2	-	28162770	MOLM13	viability	GGCCACCAGGAAGTCAGAGATGG	PROKR1	ENSG00000169618	0.859080138869055	[243]	[319]	6	hSpCas9	negative selection	11572411
68645856	68645879	2	-	28162770	MOLM13	viability	GAAGCTGGTGGAAGTGTTGGTGG	PROKR1	ENSG00000169618	0.42409426366489417	[300]	[291]	3	hSpCas9	negative selection	11572412
68646024	68646047	2	-	28162770	MOLM13	viability	GACCAGCATGATGCCCACCAGGG	PROKR1	ENSG00000169618	0.503211363444134	[1048]	[1074]	4	hSpCas9	negative selection	11572413
68646226	68646249	2	-	28162770	MOLM13	viability	GGTAGTTGACAGAGGTGCACAGG	PROKR1	ENSG00000169618	-2.879276004841806	[172]	[16]	-8	hSpCas9	negative selection	11572414
68646247	68646270	2	-	28162770	MOLM13	viability	CATAGAGAGAGACAGTGCGCAGG	PROKR1	ENSG00000169618	0.5332918567662183	[344]	[360]	4	hSpCas9	negative selection	11572415
68646160	68646183	2	+	28162770	MOLM13	viability	TGTCTGCTGCCCCTTTGAGATGG	PROKR1	ENSG00000169618	-1.1570711871084964	[255]	[82]	-6	hSpCas9	negative selection	11572416
68645829	68645852	2	-	28162770	HEL	viability	GTCATCCATGAACCCCATGGTGG	PROKR1	ENSG00000169618	0.2935033911172593	[399]	[313]	2	hSpCas9	negative selection	11741773
68646276	68646299	2	-	28162770	HEL	viability	GGCGATGGCCAGCAGGGCATTGG	PROKR1	ENSG00000169618	-1.0971092706989707	[333]	[99]	-6	hSpCas9	negative selection	11741774
68645894	68645917	2	-	28162770	HEL	viability	GAAGTGGCATGGGCTCCATGAGG	PROKR1	ENSG00000169618	-0.12899218032652593	[489]	[286]	-1	hSpCas9	negative selection	11741775
68645910	68645933	2	-	28162770	HEL	viability	GAAGTTGAATGGGAAGGAAGTGG	PROKR1	ENSG00000169618	-0.5199906680377517	[149]	[66]	-4	hSpCas9	negative selection	11741776
68646135	68646158	2	-	28162770	HEL	viability	GGCCACCAGGAAGTCAGAGATGG	PROKR1	ENSG00000169618	-0.10350457575385996	[311]	[185]	0	hSpCas9	negative selection	11741777
68645856	68645879	2	-	28162770	HEL	viability	GAAGCTGGTGGAAGTGTTGGTGG	PROKR1	ENSG00000169618	0.9354186995826757	[288]	[353]	7	hSpCas9	negative selection	11741778
68646024	68646047	2	-	28162770	HEL	viability	GACCAGCATGATGCCCACCAGGG	PROKR1	ENSG00000169618	-0.1664388256640652	[791]	[451]	-1	hSpCas9	negative selection	11741779
68646226	68646249	2	-	28162770	HEL	viability	GGTAGTTGACAGAGGTGCACAGG	PROKR1	ENSG00000169618	0.8866644148864462	[113]	[134]	7	hSpCas9	negative selection	11741780
68646247	68646270	2	-	28162770	HEL	viability	CATAGAGAGAGACAGTGCGCAGG	PROKR1	ENSG00000169618	-0.1675999484960684	[241]	[137]	-1	hSpCas9	negative selection	11741781
68646160	68646183	2	+	28162770	HEL	viability	TGTCTGCTGCCCCTTTGAGATGG	PROKR1	ENSG00000169618	-0.6886703158978907	[228]	[90]	-4	hSpCas9	negative selection	11741782
68645829	68645852	2	-	28162770	MV411	viability	GTCATCCATGAACCCCATGGTGG	PROKR1	ENSG00000169618	0.28952888427180823	[303]	[312]	2	hSpCas9	negative selection	11911139
68646276	68646299	2	-	28162770	MV411	viability	GGCGATGGCCAGCAGGGCATTGG	PROKR1	ENSG00000169618	-0.4845446358691752	[288]	[173]	-4	hSpCas9	negative selection	11911140
68645894	68645917	2	-	28162770	MV411	viability	GAAGTGGCATGGGCTCCATGAGG	PROKR1	ENSG00000169618	-0.5950211722307445	[415]	[231]	-4	hSpCas9	negative selection	11911141
68645910	68645933	2	-	28162770	MV411	viability	GAAGTTGAATGGGAAGGAAGTGG	PROKR1	ENSG00000169618	-0.9148338781161018	[140]	[62]	-6	hSpCas9	negative selection	11911142
68646135	68646158	2	-	28162770	MV411	viability	GGCCACCAGGAAGTCAGAGATGG	PROKR1	ENSG00000169618	0.4487359404845991	[186]	[214]	4	hSpCas9	negative selection	11911143
68645856	68645879	2	-	28162770	MV411	viability	GAAGCTGGTGGAAGTGTTGGTGG	PROKR1	ENSG00000169618	1.2675591467035487	[177]	[360]	9	hSpCas9	negative selection	11911144
68646024	68646047	2	-	28162770	MV411	viability	GACCAGCATGATGCCCACCAGGG	PROKR1	ENSG00000169618	0.5572202158080484	[667]	[827]	5	hSpCas9	negative selection	11911145
68646226	68646249	2	-	28162770	MV411	viability	GGTAGTTGACAGAGGTGCACAGG	PROKR1	ENSG00000169618	0.590921789036585	[92]	[117]	5	hSpCas9	negative selection	11911146
68646247	68646270	2	-	28162770	MV411	viability	CATAGAGAGAGACAGTGCGCAGG	PROKR1	ENSG00000169618	-0.014267794578498694	[216]	[180]	0	hSpCas9	negative selection	11911147
68646160	68646183	2	+	28162770	MV411	viability	TGTCTGCTGCCCCTTTGAGATGG	PROKR1	ENSG00000169618	0.806560046568672	[168]	[248]	7	hSpCas9	negative selection	11911148
68645829	68645852	2	-	28162770	MONOMAC1	viability	GTCATCCATGAACCCCATGGTGG	PROKR1	ENSG00000169618	-0.009758278866973336	[201]	[229]	0	hSpCas9	negative selection	12080505
68646276	68646299	2	-	28162770	MONOMAC1	viability	GGCGATGGCCAGCAGGGCATTGG	PROKR1	ENSG00000169618	0.31165975943353513	[122]	[174]	3	hSpCas9	negative selection	12080506
68645894	68645917	2	-	28162770	MONOMAC1	viability	GAAGTGGCATGGGCTCCATGAGG	PROKR1	ENSG00000169618	0.6921563670545119	[256]	[475]	6	hSpCas9	negative selection	12080507
68645910	68645933	2	-	28162770	MONOMAC1	viability	GAAGTTGAATGGGAAGGAAGTGG	PROKR1	ENSG00000169618	-1.0164646014177325	[89]	[50]	-7	hSpCas9	negative selection	12080508
68646135	68646158	2	-	28162770	MONOMAC1	viability	GGCCACCAGGAAGTCAGAGATGG	PROKR1	ENSG00000169618	1.4914302294154624	[120]	[389]	9	hSpCas9	negative selection	12080509
68645856	68645879	2	-	28162770	MONOMAC1	viability	GAAGCTGGTGGAAGTGTTGGTGG	PROKR1	ENSG00000169618	0.5936743188781788	[136]	[236]	6	hSpCas9	negative selection	12080510
68646024	68646047	2	-	28162770	MONOMAC1	viability	GACCAGCATGATGCCCACCAGGG	PROKR1	ENSG00000169618	0.8476417433716719	[460]	[950]	7	hSpCas9	negative selection	12080511
68646226	68646249	2	-	28162770	MONOMAC1	viability	GGTAGTTGACAGAGGTGCACAGG	PROKR1	ENSG00000169618	0.5121837566237484	[62]	[102]	5	hSpCas9	negative selection	12080512
68646247	68646270	2	-	28162770	MONOMAC1	viability	CATAGAGAGAGACAGTGCGCAGG	PROKR1	ENSG00000169618	-0.5638191777311763	[97]	[75]	-5	hSpCas9	negative selection	12080513
68646160	68646183	2	+	28162770	MONOMAC1	viability	TGTCTGCTGCCCCTTTGAGATGG	PROKR1	ENSG00000169618	0.13253131002994054	[112]	[141]	1	hSpCas9	negative selection	12080514
68645829	68645852	2	-	28162770	OCIAML2	viability	GTCATCCATGAACCCCATGGTGG	PROKR1	ENSG00000169618	0.6059914563607514	[54]	[463]	6	hSpCas9	negative selection	12249871
68646276	68646299	2	-	28162770	OCIAML2	viability	GGCGATGGCCAGCAGGGCATTGG	PROKR1	ENSG00000169618	0.177897804256461	[36]	[231]	1	hSpCas9	negative selection	12249872
68645894	68645917	2	-	28162770	OCIAML2	viability	GAAGTGGCATGGGCTCCATGAGG	PROKR1	ENSG00000169618	-0.6262806957023554	[87]	[315]	-5	hSpCas9	negative selection	12249873
68645910	68645933	2	-	28162770	OCIAML2	viability	GAAGTTGAATGGGAAGGAAGTGG	PROKR1	ENSG00000169618	-1.470629825242161	[19]	[39]	-7	hSpCas9	negative selection	12249874
68646135	68646158	2	-	28162770	OCIAML2	viability	GGCCACCAGGAAGTCAGAGATGG	PROKR1	ENSG00000169618	-0.38505409353608727	[44]	[190]	-3	hSpCas9	negative selection	12249875
68645856	68645879	2	-	28162770	OCIAML2	viability	GAAGCTGGTGGAAGTGTTGGTGG	PROKR1	ENSG00000169618	0.08879758337185738	[37]	[223]	0	hSpCas9	negative selection	12249876
68646024	68646047	2	-	28162770	OCIAML2	viability	GACCAGCATGATGCCCACCAGGG	PROKR1	ENSG00000169618	0.4648299225631285	[119]	[917]	4	hSpCas9	negative selection	12249877
68646226	68646249	2	-	28162770	OCIAML2	viability	GGTAGTTGACAGAGGTGCACAGG	PROKR1	ENSG00000169618	0.4128561660314136	[28]	[213]	4	hSpCas9	negative selection	12249878
68646247	68646270	2	-	28162770	OCIAML2	viability	CATAGAGAGAGACAGTGCGCAGG	PROKR1	ENSG00000169618	0.3944405946717303	[41]	[305]	4	hSpCas9	negative selection	12249879
68646160	68646183	2	+	28162770	OCIAML2	viability	TGTCTGCTGCCCCTTTGAGATGG	PROKR1	ENSG00000169618	-0.5195394257231076	[29]	[115]	-4	hSpCas9	negative selection	12249880
68645829	68645852	2	-	28162770	OCIAML3	viability	GTCATCCATGAACCCCATGGTGG	PROKR1	ENSG00000169618	1.6775250712105718	[66]	[646]	9	hSpCas9	negative selection	12419237
68646276	68646299	2	-	28162770	OCIAML3	viability	GGCGATGGCCAGCAGGGCATTGG	PROKR1	ENSG00000169618	-0.4371387917072971	[73]	[164]	-3	hSpCas9	negative selection	12419238
68645894	68645917	2	-	28162770	OCIAML3	viability	GAAGTGGCATGGGCTCCATGAGG	PROKR1	ENSG00000169618	0.459987249316566	[117]	[489]	4	hSpCas9	negative selection	12419239
68645910	68645933	2	-	28162770	OCIAML3	viability	GAAGTTGAATGGGAAGGAAGTGG	PROKR1	ENSG00000169618	-0.39845683120635633	[30]	[70]	-3	hSpCas9	negative selection	12419240
68646135	68646158	2	-	28162770	OCIAML3	viability	GGCCACCAGGAAGTCAGAGATGG	PROKR1	ENSG00000169618	-0.9328095537759219	[42]	[67]	-6	hSpCas9	negative selection	12419241
68645856	68645879	2	-	28162770	OCIAML3	viability	GAAGCTGGTGGAAGTGTTGGTGG	PROKR1	ENSG00000169618	0.6194737271048888	[57]	[268]	5	hSpCas9	negative selection	12419242
68646024	68646047	2	-	28162770	OCIAML3	viability	GACCAGCATGATGCCCACCAGGG	PROKR1	ENSG00000169618	0.10593876441123706	[224]	[730]	1	hSpCas9	negative selection	12419243
68646226	68646249	2	-	28162770	OCIAML3	viability	GGTAGTTGACAGAGGTGCACAGG	PROKR1	ENSG00000169618	-0.2808497550645329	[32]	[81]	-2	hSpCas9	negative selection	12419244
68646247	68646270	2	-	28162770	OCIAML3	viability	CATAGAGAGAGACAGTGCGCAGG	PROKR1	ENSG00000169618	1.0631046461528286	[38]	[245]	8	hSpCas9	negative selection	12419245
68646160	68646183	2	+	28162770	OCIAML3	viability	TGTCTGCTGCCCCTTTGAGATGG	PROKR1	ENSG00000169618	1.1596366949886732	[42]	[289]	8	hSpCas9	negative selection	12419246