Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:128674
• Symbol:PROKR2
• Description:prokineticin receptor 2

DataSource: http://genomecrispr.dkfz.de/#!/results/PROKR2

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
5313962	5313985	20	+	26472758	Jiyoye	viability	GGTGCGCAGGTAGTTGACGGAGG	PROKR2	ENSG00000101292	0.4071753815058733	[56]	[56]	3	hSpCas9	negative selection	127812
5314189	5314212	20	-	26472758	Jiyoye	viability	GATCGTCATTGGCATTGCACTGG	PROKR2	ENSG00000101292	0.20687673102004234	[215]	[187]	1	hSpCas9	negative selection	127813
5314302	5314325	20	+	26472758	Jiyoye	viability	GAGGAGGCATGGTCTTGGGGTGG	PROKR2	ENSG00000101292	-0.8515588868942949	[66]	[27]	-5	hSpCas9	negative selection	127814
5314286	5314309	20	+	26472758	Jiyoye	viability	GAAGTTAAAGGAGAGGGAGGAGG	PROKR2	ENSG00000101292	0.6702097873396673	[59]	[71]	5	hSpCas9	negative selection	127815
5313941	5313964	20	+	26472758	Jiyoye	viability	GGTGGAGACGTAGAGGGAGACGG	PROKR2	ENSG00000101292	-4.604051873917381	[128]	[3]	-9	hSpCas9	negative selection	127816
5314061	5314084	20	+	26472758	Jiyoye	viability	GGCCACCAGGAAGTCGGAGATGG	PROKR2	ENSG00000101292	0.6282544708982889	[156]	[182]	4	hSpCas9	negative selection	127817
5314246	5314269	20	+	26472758	Jiyoye	viability	CCTCATCCTCATCCATAGGGAGG	PROKR2	ENSG00000101292	5.635994072001754	[1]	[74]	9	hSpCas9	negative selection	127818
5314036	5314059	20	-	26472758	Jiyoye	viability	CATCTGCTGCCCCTTCGAGATGG	PROKR2	ENSG00000101292	-0.24490131507381974	[43]	[27]	-2	hSpCas9	negative selection	127819
5313920	5313943	20	+	26472758	Jiyoye	viability	GGCAATGGCCAGCAAGGCATTGG	PROKR2	ENSG00000101292	0.13116312167386956	[401]	[331]	1	hSpCas9	negative selection	127820
5314229	5314252	20	-	26472758	Jiyoye	viability	ATGAGGACATGACCAAGACCCGG	PROKR2	ENSG00000101292	0.39746022667266173	[148]	[147]	3	hSpCas9	negative selection	127821
5313962	5313985	20	+	26472758	KBM7	viability	GGTGCGCAGGTAGTTGACGGAGG	PROKR2	ENSG00000101292	0.029957577487209286	[535,234]	[214,145]	0	hSpCas9	negative selection	318930
5314189	5314212	20	-	26472758	KBM7	viability	GATCGTCATTGGCATTGCACTGG	PROKR2	ENSG00000101292	0.5772969779203245	[748,1131]	[756,604]	6	hSpCas9	negative selection	318931
5314302	5314325	20	+	26472758	KBM7	viability	GAGGAGGCATGGTCTTGGGGTGG	PROKR2	ENSG00000101292	-0.5901584058621221	[169,157]	[45,55]	-5	hSpCas9	negative selection	318932
5314286	5314309	20	+	26472758	KBM7	viability	GAAGTTAAAGGAGAGGGAGGAGG	PROKR2	ENSG00000101292	-0.6940777279829256	[328,176]	[106,39]	-5	hSpCas9	negative selection	318933
5313941	5313964	20	+	26472758	KBM7	viability	GGTGGAGACGTAGAGGGAGACGG	PROKR2	ENSG00000101292	-2.6695395652327183	[355,235]	[20,21]	-9	hSpCas9	negative selection	318934
5314061	5314084	20	+	26472758	KBM7	viability	GGCCACCAGGAAGTCGGAGATGG	PROKR2	ENSG00000101292	0.0401141001672749	[685,452]	[319,226]	0	hSpCas9	negative selection	318935
5314246	5314269	20	+	26472758	KBM7	viability	CCTCATCCTCATCCATAGGGAGG	PROKR2	ENSG00000101292	1.5825817993515372	[310,437]	[508,565]	9	hSpCas9	negative selection	318936
5314036	5314059	20	-	26472758	KBM7	viability	CATCTGCTGCCCCTTCGAGATGG	PROKR2	ENSG00000101292	-0.38015439211086677	[322,400]	[144,121]	-3	hSpCas9	negative selection	318937
5313920	5313943	20	+	26472758	KBM7	viability	GGCAATGGCCAGCAAGGCATTGG	PROKR2	ENSG00000101292	0.19699574941843	[1762,1516]	[806,947]	2	hSpCas9	negative selection	318938
5314229	5314252	20	-	26472758	KBM7	viability	ATGAGGACATGACCAAGACCCGG	PROKR2	ENSG00000101292	0.43549154130199386	[521,650]	[379,377]	5	hSpCas9	negative selection	318939
5313962	5313985	20	+	26472758	Raji	viability	GGTGCGCAGGTAGTTGACGGAGG	PROKR2	ENSG00000101292	0.44441852265117027	[170]	[53]	4	hSpCas9	negative selection	510048
5314189	5314212	20	-	26472758	Raji	viability	GATCGTCATTGGCATTGCACTGG	PROKR2	ENSG00000101292	-0.1578219695018216	[398]	[82]	-1	hSpCas9	negative selection	510049
5314302	5314325	20	+	26472758	Raji	viability	GAGGAGGCATGGTCTTGGGGTGG	PROKR2	ENSG00000101292	-3.2383913014681314	[121]	[2]	-9	hSpCas9	negative selection	510050
5314286	5314309	20	+	26472758	Raji	viability	GAAGTTAAAGGAGAGGGAGGAGG	PROKR2	ENSG00000101292	-1.7235582070016204	[184]	[12]	-8	hSpCas9	negative selection	510051
5313941	5313964	20	+	26472758	Raji	viability	GGTGGAGACGTAGAGGGAGACGG	PROKR2	ENSG00000101292	-2.8312159199622577	[91]	[2]	-9	hSpCas9	negative selection	510052
5314061	5314084	20	+	26472758	Raji	viability	GGCCACCAGGAAGTCGGAGATGG	PROKR2	ENSG00000101292	0.7667593467763322	[232]	[91]	7	hSpCas9	negative selection	510053
5314246	5314269	20	+	26472758	Raji	viability	CCTCATCCTCATCCATAGGGAGG	PROKR2	ENSG00000101292	0.7025418032006443	[187]	[70]	6	hSpCas9	negative selection	510054
5314036	5314059	20	-	26472758	Raji	viability	CATCTGCTGCCCCTTCGAGATGG	PROKR2	ENSG00000101292	0.42747263059718055	[156]	[48]	4	hSpCas9	negative selection	510055
5313920	5313943	20	+	26472758	Raji	viability	GGCAATGGCCAGCAAGGCATTGG	PROKR2	ENSG00000101292	-0.24488063788472147	[816]	[159]	-2	hSpCas9	negative selection	510056
5314229	5314252	20	-	26472758	Raji	viability	ATGAGGACATGACCAAGACCCGG	PROKR2	ENSG00000101292	1.2514597130470209	[218]	[120]	9	hSpCas9	negative selection	510057
5313962	5313985	20	+	26472758	K562	viability	GGTGCGCAGGTAGTTGACGGAGG	PROKR2	ENSG00000101292	-0.050123479425836504	[286]	[233]	0	hSpCas9	negative selection	701166
5314189	5314212	20	-	26472758	K562	viability	GATCGTCATTGGCATTGCACTGG	PROKR2	ENSG00000101292	0.7342967356624467	[600]	[843]	6	hSpCas9	negative selection	701167
5314302	5314325	20	+	26472758	K562	viability	GAGGAGGCATGGTCTTGGGGTGG	PROKR2	ENSG00000101292	-3.825970600224951	[251]	[14]	-9	hSpCas9	negative selection	701168
5314286	5314309	20	+	26472758	K562	viability	GAAGTTAAAGGAGAGGGAGGAGG	PROKR2	ENSG00000101292	-2.5354554579690505	[363]	[52]	-8	hSpCas9	negative selection	701169
5313941	5313964	20	+	26472758	K562	viability	GGTGGAGACGTAGAGGGAGACGG	PROKR2	ENSG00000101292	-6.582129759624468	[453]	[3]	-9	hSpCas9	negative selection	701170
5314061	5314084	20	+	26472758	K562	viability	GGCCACCAGGAAGTCGGAGATGG	PROKR2	ENSG00000101292	0.2947922501815662	[590]	[611]	2	hSpCas9	negative selection	701171
5314246	5314269	20	+	26472758	K562	viability	CCTCATCCTCATCCATAGGGAGG	PROKR2	ENSG00000101292	0.9937085402132482	[372]	[626]	8	hSpCas9	negative selection	701172
5314036	5314059	20	-	26472758	K562	viability	CATCTGCTGCCCCTTCGAGATGG	PROKR2	ENSG00000101292	0.8420180540655287	[340]	[515]	7	hSpCas9	negative selection	701173
5313920	5313943	20	+	26472758	K562	viability	GGCAATGGCCAGCAAGGCATTGG	PROKR2	ENSG00000101292	-0.07180522790431754	[1198]	[962]	0	hSpCas9	negative selection	701174
5314229	5314252	20	-	26472758	K562	viability	ATGAGGACATGACCAAGACCCGG	PROKR2	ENSG00000101292	0.2685924013080291	[650]	[661]	2	hSpCas9	negative selection	701175
5302124	5302147	20	-	26627737	DLD1	viability	TGCACTGGCGTCCCTCCCAGCGG	PROKR2	ENSG00000101292	0.057999513252811274	[1270]	[629,403,233]	0	hSpCas9	negative selection	815179
5302501	5302524	20	+	26627737	DLD1	viability	ACTCGACACCAAAGATGAAGAGG	PROKR2	ENSG00000101292	0.5997046831956939	[285]	[154,111,137]	6	hSpCas9	negative selection	815180
5302631	5302654	20	+	26627737	DLD1	viability	CGATGGGATGGCAATGAGAATGG	PROKR2	ENSG00000101292	0.21947980139589895	[944]	[425,263,338]	2	hSpCas9	negative selection	815181
5313949	5313972	20	+	26627737	DLD1	viability	CGTAGAGGGAGACGGTGCGCAGG	PROKR2	ENSG00000101292	-0.2474735790959306	[938]	[342,249,161]	-3	hSpCas9	negative selection	815182
5314189	5314212	20	-	26627737	DLD1	viability	GATCGTCATTGGCATTGCACTGG	PROKR2	ENSG00000101292	0.5214498691565651	[368]	[130,228,142]	5	hSpCas9	negative selection	815183
5314246	5314269	20	+	26627737	DLD1	viability	CCTCATCCTCATCCATAGGGAGG	PROKR2	ENSG00000101292	0.9619748123452958	[287]	[124,207,191]	8	hSpCas9	negative selection	815184
5302124	5302147	20	-	26627737	GBM cells	viability after 5 days	TGCACTGGCGTCCCTCCCAGCGG	PROKR2	ENSG00000101292	-0.4501603620147997	[455]	[167,189]	-6	hSpCas9	negative selection	897494
5302501	5302524	20	+	26627737	GBM cells	viability after 5 days	ACTCGACACCAAAGATGAAGAGG	PROKR2	ENSG00000101292	0.31245402577802717	[240]	[134,185]	5	hSpCas9	negative selection	897495
5302631	5302654	20	+	26627737	GBM cells	viability after 5 days	CGATGGGATGGCAATGAGAATGG	PROKR2	ENSG00000101292	0.3722643849889311	[496]	[312,376]	6	hSpCas9	negative selection	897496
5313949	5313972	20	+	26627737	GBM cells	viability after 5 days	CGTAGAGGGAGACGGTGCGCAGG	PROKR2	ENSG00000101292	0.5257451015544016	[282]	[215,220]	7	hSpCas9	negative selection	897497
5314189	5314212	20	-	26627737	GBM cells	viability after 5 days	GATCGTCATTGGCATTGCACTGG	PROKR2	ENSG00000101292	-0.3664306916353093	[124]	[56,46]	-5	hSpCas9	negative selection	897498
5314246	5314269	20	+	26627737	GBM cells	viability after 5 days	CCTCATCCTCATCCATAGGGAGG	PROKR2	ENSG00000101292	0.7284144378232462	[156]	[158,119]	8	hSpCas9	negative selection	897499
5302124	5302147	20	-	26627737	GBM cells	viability after 13 days	TGCACTGGCGTCCCTCCCAGCGG	PROKR2	ENSG00000101292	-0.3043340663063544	[455]	[233,172]	-4	hSpCas9	negative selection	979809
5302501	5302524	20	+	26627737	GBM cells	viability after 13 days	ACTCGACACCAAAGATGAAGAGG	PROKR2	ENSG00000101292	0.4235130809683848	[240]	[165,182]	5	hSpCas9	negative selection	979810
5302631	5302654	20	+	26627737	GBM cells	viability after 13 days	CGATGGGATGGCAATGAGAATGG	PROKR2	ENSG00000101292	0.4806334336564624	[496]	[442,321]	6	hSpCas9	negative selection	979811
5313949	5313972	20	+	26627737	GBM cells	viability after 13 days	CGTAGAGGGAGACGGTGCGCAGG	PROKR2	ENSG00000101292	-0.3502821500435125	[282]	[120,119]	-4	hSpCas9	negative selection	979812
5314189	5314212	20	-	26627737	GBM cells	viability after 13 days	GATCGTCATTGGCATTGCACTGG	PROKR2	ENSG00000101292	-0.376728135983873	[124]	[38,62]	-4	hSpCas9	negative selection	979813
5314246	5314269	20	+	26627737	GBM cells	viability after 13 days	CCTCATCCTCATCCATAGGGAGG	PROKR2	ENSG00000101292	0.7338638648966275	[156]	[171,116]	8	hSpCas9	negative selection	979814
5302124	5302147	20	-	26627737	GBM cells	viability after 21 days	TGCACTGGCGTCCCTCCCAGCGG	PROKR2	ENSG00000101292	0.3319232215659751	[455]	[315,307]	3	hSpCas9	negative selection	1062124
5302501	5302524	20	+	26627737	GBM cells	viability after 21 days	ACTCGACACCAAAGATGAAGAGG	PROKR2	ENSG00000101292	0.7605317889188392	[240]	[237,206]	7	hSpCas9	negative selection	1062125
5302631	5302654	20	+	26627737	GBM cells	viability after 21 days	CGATGGGATGGCAATGAGAATGG	PROKR2	ENSG00000101292	0.693850204109399	[496]	[453,420]	7	hSpCas9	negative selection	1062126
5313949	5313972	20	+	26627737	GBM cells	viability after 21 days	CGTAGAGGGAGACGGTGCGCAGG	PROKR2	ENSG00000101292	-0.2625476559755536	[282]	[135,120]	-2	hSpCas9	negative selection	1062127
5314189	5314212	20	-	26627737	GBM cells	viability after 21 days	GATCGTCATTGGCATTGCACTGG	PROKR2	ENSG00000101292	0.3014132032381248	[124]	[90,76]	3	hSpCas9	negative selection	1062128
5314246	5314269	20	+	26627737	GBM cells	viability after 21 days	CCTCATCCTCATCCATAGGGAGG	PROKR2	ENSG00000101292	0.8068237114005083	[156]	[155,142]	7	hSpCas9	negative selection	1062129
5302124	5302147	20	-	26627737	RPE1	viability after 9 days	TGCACTGGCGTCCCTCCCAGCGG	PROKR2	ENSG00000101292	0.16818520851286134	[968]	[339,341]	1	hSpCas9	negative selection	1144439
5302501	5302524	20	+	26627737	RPE1	viability after 9 days	ACTCGACACCAAAGATGAAGAGG	PROKR2	ENSG00000101292	0.7022780844586967	[660]	[220,485]	4	hSpCas9	negative selection	1144440
5302631	5302654	20	+	26627737	RPE1	viability after 9 days	CGATGGGATGGCAATGAGAATGG	PROKR2	ENSG00000101292	0.6062825230144471	[1829]	[955,763]	4	hSpCas9	negative selection	1144441
5313949	5313972	20	+	26627737	RPE1	viability after 9 days	CGTAGAGGGAGACGGTGCGCAGG	PROKR2	ENSG00000101292	-0.7349695785034882	[1035]	[162,235]	-5	hSpCas9	negative selection	1144442
5314189	5314212	20	-	26627737	RPE1	viability after 9 days	GATCGTCATTGGCATTGCACTGG	PROKR2	ENSG00000101292	-0.5861934692607593	[468]	[92,103]	-4	hSpCas9	negative selection	1144443
5314246	5314269	20	+	26627737	RPE1	viability after 9 days	CCTCATCCTCATCCATAGGGAGG	PROKR2	ENSG00000101292	2.1838204849740355	[157]	[129,346]	9	hSpCas9	negative selection	1144444
5302124	5302147	20	-	26627737	RPE1	viability after 12 days	TGCACTGGCGTCCCTCCCAGCGG	PROKR2	ENSG00000101292	0.5117004073475449	[968]	[274,472]	3	hSpCas9	negative selection	1226754
5302501	5302524	20	+	26627737	RPE1	viability after 12 days	ACTCGACACCAAAGATGAAGAGG	PROKR2	ENSG00000101292	0.4837943924017625	[660]	[140,361]	3	hSpCas9	negative selection	1226755
5302631	5302654	20	+	26627737	RPE1	viability after 12 days	CGATGGGATGGCAATGAGAATGG	PROKR2	ENSG00000101292	0.888976049464467	[1829]	[1113,694]	5	hSpCas9	negative selection	1226756
5313949	5313972	20	+	26627737	RPE1	viability after 12 days	CGTAGAGGGAGACGGTGCGCAGG	PROKR2	ENSG00000101292	-0.45211575562463374	[1035]	[167,240]	-3	hSpCas9	negative selection	1226757
5314189	5314212	20	-	26627737	RPE1	viability after 12 days	GATCGTCATTGGCATTGCACTGG	PROKR2	ENSG00000101292	-0.4768037734049715	[468]	[74,106]	-3	hSpCas9	negative selection	1226758
5314246	5314269	20	+	26627737	RPE1	viability after 12 days	CCTCATCCTCATCCATAGGGAGG	PROKR2	ENSG00000101292	2.3194731751765993	[157]	[139,287]	9	hSpCas9	negative selection	1226759
5302124	5302147	20	-	26627737	RPE1	viability after 15 days	TGCACTGGCGTCCCTCCCAGCGG	PROKR2	ENSG00000101292	0.5074703949451707	[968]	[464,316]	3	hSpCas9	negative selection	1309069
5302501	5302524	20	+	26627737	RPE1	viability after 15 days	ACTCGACACCAAAGATGAAGAGG	PROKR2	ENSG00000101292	0.44431530624455445	[660]	[286,222]	3	hSpCas9	negative selection	1309070
5302631	5302654	20	+	26627737	RPE1	viability after 15 days	CGATGGGATGGCAATGAGAATGG	PROKR2	ENSG00000101292	0.7518635076214739	[1829]	[1167,585]	4	hSpCas9	negative selection	1309071
5313949	5313972	20	+	26627737	RPE1	viability after 15 days	CGTAGAGGGAGACGGTGCGCAGG	PROKR2	ENSG00000101292	-0.36841027756109035	[1035]	[197,254]	-2	hSpCas9	negative selection	1309072
5314189	5314212	20	-	26627737	RPE1	viability after 15 days	GATCGTCATTGGCATTGCACTGG	PROKR2	ENSG00000101292	-0.7359821416403676	[468]	[98,60]	-5	hSpCas9	negative selection	1309073
5314246	5314269	20	+	26627737	RPE1	viability after 15 days	CCTCATCCTCATCCATAGGGAGG	PROKR2	ENSG00000101292	2.234279373830044	[157]	[108,307]	9	hSpCas9	negative selection	1309074
5302124	5302147	20	-	26627737	RPE1	viability after 18 days	TGCACTGGCGTCCCTCCCAGCGG	PROKR2	ENSG00000101292	0.024674951854459504	[968]	[280,249]	0	hSpCas9	negative selection	1391384
5302501	5302524	20	+	26627737	RPE1	viability after 18 days	ACTCGACACCAAAGATGAAGAGG	PROKR2	ENSG00000101292	0.33049942957028794	[660]	[276,167]	2	hSpCas9	negative selection	1391385
5302631	5302654	20	+	26627737	RPE1	viability after 18 days	CGATGGGATGGCAATGAGAATGG	PROKR2	ENSG00000101292	0.5655901952073921	[1829]	[873,577]	3	hSpCas9	negative selection	1391386
5313949	5313972	20	+	26627737	RPE1	viability after 18 days	CGTAGAGGGAGACGGTGCGCAGG	PROKR2	ENSG00000101292	-1.0841451491763126	[1035]	[98,166]	-6	hSpCas9	negative selection	1391387
5314189	5314212	20	-	26627737	RPE1	viability after 18 days	GATCGTCATTGGCATTGCACTGG	PROKR2	ENSG00000101292	-0.5721343469228268	[468]	[88,80]	-4	hSpCas9	negative selection	1391388
5314246	5314269	20	+	26627737	RPE1	viability after 18 days	CCTCATCCTCATCCATAGGGAGG	PROKR2	ENSG00000101292	2.2080434507281894	[157]	[109,289]	9	hSpCas9	negative selection	1391389
5302124	5302147	20	-	26627737	HeLa	viability after 8 days	TGCACTGGCGTCCCTCCCAGCGG	PROKR2	ENSG00000101292	-1.2234384986282452	[1003]	[350,127,122]	-8	hSpCas9	negative selection	1473699
5302501	5302524	20	+	26627737	HeLa	viability after 8 days	ACTCGACACCAAAGATGAAGAGG	PROKR2	ENSG00000101292	0.38019892509067493	[322]	[191,193,165]	3	hSpCas9	negative selection	1473700
5302631	5302654	20	+	26627737	HeLa	viability after 8 days	CGATGGGATGGCAATGAGAATGG	PROKR2	ENSG00000101292	0.2820225126902286	[690]	[490,276,356]	2	hSpCas9	negative selection	1473701
5313949	5313972	20	+	26627737	HeLa	viability after 8 days	CGTAGAGGGAGACGGTGCGCAGG	PROKR2	ENSG00000101292	0.8389333353802594	[437]	[516,225,319]	7	hSpCas9	negative selection	1473702
5314189	5314212	20	-	26627737	HeLa	viability after 8 days	GATCGTCATTGGCATTGCACTGG	PROKR2	ENSG00000101292	-0.1814639694739324	[234]	[118,54,101]	-2	hSpCas9	negative selection	1473703
5314246	5314269	20	+	26627737	HeLa	viability after 8 days	CCTCATCCTCATCCATAGGGAGG	PROKR2	ENSG00000101292	0.06677529834234508	[127]	[78,33,65]	0	hSpCas9	negative selection	1473704
5302124	5302147	20	-	26627737	HeLa	viability after 12 days	TGCACTGGCGTCCCTCCCAGCGG	PROKR2	ENSG00000101292	-0.5140869081495149	[1003]	[519,264,95]	-4	hSpCas9	negative selection	1556014
5302501	5302524	20	+	26627737	HeLa	viability after 12 days	ACTCGACACCAAAGATGAAGAGG	PROKR2	ENSG00000101292	0.09895918204115267	[322]	[133,129,165]	0	hSpCas9	negative selection	1556015
5302631	5302654	20	+	26627737	HeLa	viability after 12 days	CGATGGGATGGCAATGAGAATGG	PROKR2	ENSG00000101292	0.4227591716752056	[690]	[437,278,443]	3	hSpCas9	negative selection	1556016
5313949	5313972	20	+	26627737	HeLa	viability after 12 days	CGTAGAGGGAGACGGTGCGCAGG	PROKR2	ENSG00000101292	0.5090205478758303	[437]	[419,233,125]	4	hSpCas9	negative selection	1556017
5314189	5314212	20	-	26627737	HeLa	viability after 12 days	GATCGTCATTGGCATTGCACTGG	PROKR2	ENSG00000101292	0.10728666403720921	[234]	[19,145,140]	1	hSpCas9	negative selection	1556018
5314246	5314269	20	+	26627737	HeLa	viability after 12 days	CCTCATCCTCATCCATAGGGAGG	PROKR2	ENSG00000101292	0.538815260940013	[127]	[48,130,43]	4	hSpCas9	negative selection	1556019
5302124	5302147	20	-	26627737	HeLa	viability after 15 days	TGCACTGGCGTCCCTCCCAGCGG	PROKR2	ENSG00000101292	-1.500944062554772	[1003]	[136,155,139]	-8	hSpCas9	negative selection	1638329
5302501	5302524	20	+	26627737	HeLa	viability after 15 days	ACTCGACACCAAAGATGAAGAGG	PROKR2	ENSG00000101292	-0.09918936027310538	[322]	[96,131,140]	-1	hSpCas9	negative selection	1638330
5302631	5302654	20	+	26627737	HeLa	viability after 15 days	CGATGGGATGGCAATGAGAATGG	PROKR2	ENSG00000101292	0.17477208685547985	[690]	[368,300,278]	1	hSpCas9	negative selection	1638331
5313949	5313972	20	+	26627737	HeLa	viability after 15 days	CGTAGAGGGAGACGGTGCGCAGG	PROKR2	ENSG00000101292	0.08191131470855709	[437]	[117,333,108]	0	hSpCas9	negative selection	1638332
5314189	5314212	20	-	26627737	HeLa	viability after 15 days	GATCGTCATTGGCATTGCACTGG	PROKR2	ENSG00000101292	0.15804794632497277	[234]	[142,30,148]	1	hSpCas9	negative selection	1638333
5314246	5314269	20	+	26627737	HeLa	viability after 15 days	CCTCATCCTCATCCATAGGGAGG	PROKR2	ENSG00000101292	1.2451724518459963	[127]	[87,183,96]	8	hSpCas9	negative selection	1638334
5302124	5302147	20	-	26627737	HeLa	viability after 18 days	TGCACTGGCGTCCCTCCCAGCGG	PROKR2	ENSG00000101292	-1.5556915556589368	[1003]	[87,120,139]	-8	hSpCas9	negative selection	1720644
5302501	5302524	20	+	26627737	HeLa	viability after 18 days	ACTCGACACCAAAGATGAAGAGG	PROKR2	ENSG00000101292	-0.14412900312328164	[322]	[53,113,140]	-1	hSpCas9	negative selection	1720645
5302631	5302654	20	+	26627737	HeLa	viability after 18 days	CGATGGGATGGCAATGAGAATGG	PROKR2	ENSG00000101292	0.19108666482742376	[690]	[253,249,278]	1	hSpCas9	negative selection	1720646
5313949	5313972	20	+	26627737	HeLa	viability after 18 days	CGTAGAGGGAGACGGTGCGCAGG	PROKR2	ENSG00000101292	0.10907464018821761	[437]	[80,282,108]	0	hSpCas9	negative selection	1720647
5314189	5314212	20	-	26627737	HeLa	viability after 18 days	GATCGTCATTGGCATTGCACTGG	PROKR2	ENSG00000101292	0.05074171789142656	[234]	[79,26,148]	0	hSpCas9	negative selection	1720648
5314246	5314269	20	+	26627737	HeLa	viability after 18 days	CCTCATCCTCATCCATAGGGAGG	PROKR2	ENSG00000101292	1.209116265144082	[127]	[58,144,96]	8	hSpCas9	negative selection	1720649
5302124	5302147	20	-	26627737	HCT116	viability after 6 days	TGCACTGGCGTCCCTCCCAGCGG	PROKR2	ENSG00000101292	1.067143823738336	[1244]	[373,429]	6	hSpCas9	negative selection	1802959
5302501	5302524	20	+	26627737	HCT116	viability after 6 days	ACTCGACACCAAAGATGAAGAGG	PROKR2	ENSG00000101292	-0.5918002457406518	[323]	[56,20]	-3	hSpCas9	negative selection	1802960
5302631	5302654	20	+	26627737	HCT116	viability after 6 days	CGATGGGATGGCAATGAGAATGG	PROKR2	ENSG00000101292	-0.6616747853210212	[893]	[93,85]	-4	hSpCas9	negative selection	1802961
5313949	5313972	20	+	26627737	HCT116	viability after 6 days	CGTAGAGGGAGACGGTGCGCAGG	PROKR2	ENSG00000101292	1.0704674100731493	[840]	[189,325]	6	hSpCas9	negative selection	1802962
5314189	5314212	20	-	26627737	HCT116	viability after 6 days	GATCGTCATTGGCATTGCACTGG	PROKR2	ENSG00000101292	0.04474704760590112	[509]	[141,49]	0	hSpCas9	negative selection	1802963
5314246	5314269	20	+	26627737	HCT116	viability after 6 days	CCTCATCCTCATCCATAGGGAGG	PROKR2	ENSG00000101292	-0.8717008402719518	[390]	[79,7]	-5	hSpCas9	negative selection	1802964
5302124	5302147	20	-	26627737	HCT116	viability after 8 days	TGCACTGGCGTCCCTCCCAGCGG	PROKR2	ENSG00000101292	0.5189682414764152	[421]	[370,189,437]	5	hSpCas9	negative selection	1885274
5302501	5302524	20	+	26627737	HCT116	viability after 8 days	ACTCGACACCAAAGATGAAGAGG	PROKR2	ENSG00000101292	-0.10461543683261793	[422]	[237,218,193]	-1	hSpCas9	negative selection	1885275
5302631	5302654	20	+	26627737	HCT116	viability after 8 days	CGATGGGATGGCAATGAGAATGG	PROKR2	ENSG00000101292	0.01208625960958587	[659]	[417,305,376]	0	hSpCas9	negative selection	1885276
5313949	5313972	20	+	26627737	HCT116	viability after 8 days	CGTAGAGGGAGACGGTGCGCAGG	PROKR2	ENSG00000101292	-0.49842956717896325	[598]	[287,187,225]	-5	hSpCas9	negative selection	1885277
5314189	5314212	20	-	26627737	HCT116	viability after 8 days	GATCGTCATTGGCATTGCACTGG	PROKR2	ENSG00000101292	-1.5795484389359677	[340]	[84,40,62]	-9	hSpCas9	negative selection	1885278
5314246	5314269	20	+	26627737	HCT116	viability after 8 days	CCTCATCCTCATCCATAGGGAGG	PROKR2	ENSG00000101292	1.513913346687364	[101]	[132,183,163]	9	hSpCas9	negative selection	1885279
5302124	5302147	20	-	26627737	HCT116	viability after 9 days	TGCACTGGCGTCCCTCCCAGCGG	PROKR2	ENSG00000101292	0.3537058595356528	[1244]	[502,362]	2	hSpCas9	negative selection	1967589
5302501	5302524	20	+	26627737	HCT116	viability after 9 days	ACTCGACACCAAAGATGAAGAGG	PROKR2	ENSG00000101292	0.6533669914805791	[323]	[225,64]	5	hSpCas9	negative selection	1967590
5302631	5302654	20	+	26627737	HCT116	viability after 9 days	CGATGGGATGGCAATGAGAATGG	PROKR2	ENSG00000101292	-0.18106350223491663	[893]	[147,259]	-1	hSpCas9	negative selection	1967591
5313949	5313972	20	+	26627737	HCT116	viability after 9 days	CGTAGAGGGAGACGGTGCGCAGG	PROKR2	ENSG00000101292	0.16072671233494112	[840]	[307,205]	1	hSpCas9	negative selection	1967592
5314189	5314212	20	-	26627737	HCT116	viability after 9 days	GATCGTCATTGGCATTGCACTGG	PROKR2	ENSG00000101292	-1.104881015847119	[509]	[45,76]	-7	hSpCas9	negative selection	1967593
5314246	5314269	20	+	26627737	HCT116	viability after 9 days	CCTCATCCTCATCCATAGGGAGG	PROKR2	ENSG00000101292	0.028369502179514172	[390]	[120,94]	0	hSpCas9	negative selection	1967594
5302124	5302147	20	-	26627737	HCT116	viability after 12 days	TGCACTGGCGTCCCTCCCAGCGG	PROKR2	ENSG00000101292	0.5966442373274212	[421]	[359,255,385]	5	hSpCas9	negative selection	2049904
5302501	5302524	20	+	26627737	HCT116	viability after 12 days	ACTCGACACCAAAGATGAAGAGG	PROKR2	ENSG00000101292	-0.49761263204512085	[422]	[125,152,195]	-5	hSpCas9	negative selection	2049905
5302631	5302654	20	+	26627737	HCT116	viability after 12 days	CGATGGGATGGCAATGAGAATGG	PROKR2	ENSG00000101292	0.18066630455821087	[659]	[494,334,338]	2	hSpCas9	negative selection	2049906
5313949	5313972	20	+	26627737	HCT116	viability after 12 days	CGTAGAGGGAGACGGTGCGCAGG	PROKR2	ENSG00000101292	-0.26967170918256367	[598]	[374,204,191]	-3	hSpCas9	negative selection	2049907
5314189	5314212	20	-	26627737	HCT116	viability after 12 days	GATCGTCATTGGCATTGCACTGG	PROKR2	ENSG00000101292	-0.5496426898724917	[340]	[98,107,161]	-5	hSpCas9	negative selection	2049908
5314246	5314269	20	+	26627737	HCT116	viability after 12 days	CCTCATCCTCATCCATAGGGAGG	PROKR2	ENSG00000101292	1.6849869700095266	[101]	[108,269,145]	9	hSpCas9	negative selection	2049909
5302124	5302147	20	-	26627737	HCT116	viability after 15 days	TGCACTGGCGTCCCTCCCAGCGG	PROKR2	ENSG00000101292	0.5922089180842347	[421]	[322,408,358]	5	hSpCas9	negative selection	2132219
5302501	5302524	20	+	26627737	HCT116	viability after 15 days	ACTCGACACCAAAGATGAAGAGG	PROKR2	ENSG00000101292	-0.3292044609234641	[422]	[248,155,181]	-3	hSpCas9	negative selection	2132220
5302631	5302654	20	+	26627737	HCT116	viability after 15 days	CGATGGGATGGCAATGAGAATGG	PROKR2	ENSG00000101292	0.04524105608262041	[659]	[428,279,467]	0	hSpCas9	negative selection	2132221
5313949	5313972	20	+	26627737	HCT116	viability after 15 days	CGTAGAGGGAGACGGTGCGCAGG	PROKR2	ENSG00000101292	-0.649097397988863	[598]	[317,290,62]	-6	hSpCas9	negative selection	2132222
5314189	5314212	20	-	26627737	HCT116	viability after 15 days	GATCGTCATTGGCATTGCACTGG	PROKR2	ENSG00000101292	-0.7984696125115207	[340]	[132,71,134]	-7	hSpCas9	negative selection	2132223
5314246	5314269	20	+	26627737	HCT116	viability after 15 days	CCTCATCCTCATCCATAGGGAGG	PROKR2	ENSG00000101292	1.7408965310872715	[101]	[97,241,234]	9	hSpCas9	negative selection	2132224
5302124	5302147	20	-	26627737	HCT116	viability after 18 days	TGCACTGGCGTCCCTCCCAGCGG	PROKR2	ENSG00000101292	0.6548701603744953	[421]	[317,233,421]	5	hSpCas9	negative selection	2214534
5302501	5302524	20	+	26627737	HCT116	viability after 18 days	ACTCGACACCAAAGATGAAGAGG	PROKR2	ENSG00000101292	-0.8422572136529348	[422]	[97,147,92]	-6	hSpCas9	negative selection	2214535
5302631	5302654	20	+	26627737	HCT116	viability after 18 days	CGATGGGATGGCAATGAGAATGG	PROKR2	ENSG00000101292	0.7097566941761657	[659]	[601,219,774]	6	hSpCas9	negative selection	2214536
5313949	5313972	20	+	26627737	HCT116	viability after 18 days	CGTAGAGGGAGACGGTGCGCAGG	PROKR2	ENSG00000101292	-0.08254691944647496	[598]	[219,324,271]	0	hSpCas9	negative selection	2214537
5314189	5314212	20	-	26627737	HCT116	viability after 18 days	GATCGTCATTGGCATTGCACTGG	PROKR2	ENSG00000101292	-1.0116855743366002	[340]	[126,39,80]	-7	hSpCas9	negative selection	2214538
5314246	5314269	20	+	26627737	HCT116	viability after 18 days	CCTCATCCTCATCCATAGGGAGG	PROKR2	ENSG00000101292	0.6742213347131913	[101]	[38,86,110]	5	hSpCas9	negative selection	2214539
5314028	5314051	20	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CGTAGTAGTCCATCTCGAAGGGG	PROKR2	ENSG00000101292	-0.1886528685213266	[3,2]	[4,0]	-3	hSpCas9	positive selection	3013818
5314024	5314047	20	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CTTCGAGATGGACTACTACGTGG	PROKR2	ENSG00000101292	0.29079589853988136	[5,5]	[5,5]	6	hSpCas9	positive selection	3013819
5314063	5314086	20	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GGCCATCTCCGACTTCCTGGTGG	PROKR2	ENSG00000101292	-0.028000947115026806	[3,3]	[3,2]	0	hSpCas9	positive selection	3013820
5314258	5314281	20	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TGGTGATTATGACCTCCCTATGG	PROKR2	ENSG00000101292	0.19046871553005712	[4,4]	[4,3]	4	hSpCas9	positive selection	3013821
5314028	5314051	20	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CGTAGTAGTCCATCTCGAAGGGG	PROKR2	ENSG00000101292	0.08549438208962154	[3,3]	[3,1]	1	hSpCas9	positive selection	3081676
5314024	5314047	20	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CTTCGAGATGGACTACTACGTGG	PROKR2	ENSG00000101292	0.09151884863321663	[5,5]	[4,3]	1	hSpCas9	positive selection	3081677
5314063	5314086	20	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GGCCATCTCCGACTTCCTGGTGG	PROKR2	ENSG00000101292	-0.6202780300323834	[3,3]	[2,0]	-8	hSpCas9	positive selection	3081678
5314258	5314281	20	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TGGTGATTATGACCTCCCTATGG	PROKR2	ENSG00000101292	0.30365573709410026	[4,4]	[3,3]	5	hSpCas9	positive selection	3081679
5314007	5314030		-	24336571	A375	resistance to PLX after 7 days	ACGTGGTACGGCAGCTCTCCTGG	PROKR2	ENSG00000101292	-0.10616294167650416	[15,11]	[12,12]	-3	hSpCas9	positive selection	3137942
5302686	5302709		+	24336571	A375	resistance to PLX after 7 days	GCCGTTTGATAATTCATCCGTGG	PROKR2	ENSG00000101292	-0.2719129896855507	[14,17]	[12,13]	-7	hSpCas9	positive selection	3137943
5314111	5314134		+	24336571	A375	resistance to PLX after 7 days	GGTTGCGCAACTTCTTATAGCGG	PROKR2	ENSG00000101292	0.03596919586297331	[4,4]	[4,4]	1	hSpCas9	positive selection	3137944
5302486	5302509		-	24336571	A375	resistance to PLX after 7 days	TGTCGAGTTCGTGGGCCCTGTGG	PROKR2	ENSG00000101292	0.08471507412175128	[18,11]	[17,14]	3	hSpCas9	positive selection	3137945
5314007	5314030		-	24336571	A375	resistance to PLX after 14 days	ACGTGGTACGGCAGCTCTCCTGG	PROKR2	ENSG00000101292	-0.5979573298403096	[13,16]	[3,4]	-7	hSpCas9	positive selection	3195735
5302686	5302709		+	24336571	A375	resistance to PLX after 14 days	GCCGTTTGATAATTCATCCGTGG	PROKR2	ENSG00000101292	-0.5249706266363863	[15,14]	[4,3]	-6	hSpCas9	positive selection	3195736
5314111	5314134		+	24336571	A375	resistance to PLX after 14 days	GGTTGCGCAACTTCTTATAGCGG	PROKR2	ENSG00000101292	-0.175159150444123	[5,4]	[1,1]	-2	hSpCas9	positive selection	3195737
5302486	5302509		-	24336571	A375	resistance to PLX after 14 days	TGTCGAGTTCGTGGGCCCTGTGG	PROKR2	ENSG00000101292	1.9047080442854354	[14,16]	[24,32]	9	hSpCas9	positive selection	3195738
5314007	5314030		-	24336571	A375	viability after 7 days	ACGTGGTACGGCAGCTCTCCTGG	PROKR2	ENSG00000101292	0.48745819121576994	[9]	[15,11]	7	hSpCas9	negative selection	3253528
5302686	5302709		+	24336571	A375	viability after 7 days	GCCGTTTGATAATTCATCCGTGG	PROKR2	ENSG00000101292	0.33868115743164806	[13]	[14,17]	5	hSpCas9	negative selection	3253529
5314111	5314134		+	24336571	A375	viability after 7 days	GGTTGCGCAACTTCTTATAGCGG	PROKR2	ENSG00000101292	-0.2179059022728469	[5]	[4,4]	-3	hSpCas9	negative selection	3253530
5302486	5302509		-	24336571	A375	viability after 7 days	TGTCGAGTTCGTGGGCCCTGTGG	PROKR2	ENSG00000101292	0.30328746108524757	[12]	[18,11]	4	hSpCas9	negative selection	3253531
5314007	5314030		-	24336571	A375	viability after 14 days	ACGTGGTACGGCAGCTCTCCTGG	PROKR2	ENSG00000101292	0.6552039545226586	[9]	[13,16]	8	hSpCas9	negative selection	3311321
5302686	5302709		+	24336571	A375	viability after 14 days	GCCGTTTGATAATTCATCCGTGG	PROKR2	ENSG00000101292	0.2889222626386121	[13]	[15,14]	4	hSpCas9	negative selection	3311322
5314111	5314134		+	24336571	A375	viability after 14 days	GGTTGCGCAACTTCTTATAGCGG	PROKR2	ENSG00000101292	-0.1318191598776277	[5]	[5,4]	-1	hSpCas9	negative selection	3311323
5302486	5302509		-	24336571	A375	viability after 14 days	TGTCGAGTTCGTGGGCCCTGTGG	PROKR2	ENSG00000101292	0.3660719037785619	[12]	[14,16]	5	hSpCas9	negative selection	3311324
5314200	5314223	20	-	27383988	293T	resistance to West Nile virus (flavivirus)	TTCGCAGCCAAGATCGTCATTGG	PROKR2	ENSG00000101292	-1.553245423295312	[448,448]	[0,0]	-8	hSpCas9	positive selection	3387609
5314217	5314240	20	+	27383988	293T	resistance to West Nile virus (flavivirus)	TGCGAAGAAGGTCCGGGTCTTGG	PROKR2	ENSG00000101292	0.6134700216711103	[99,99]	[0,0]	3	hSpCas9	positive selection	3387610
5314193	5314216	20	+	27383988	293T	resistance to West Nile virus (flavivirus)	TGCAATGCCAATGACGATCTTGG	PROKR2	ENSG00000101292	-0.6253168379160061	[471,471]	[1,1]	-4	hSpCas9	positive selection	3387611
5314027	5314050	20	+	26780180	HT29	viability (Avana library 4 designs)	CGTAGTAGTCCATCTCGAAGGGG	PROKR2	ENSG00000101292	1.56424177476776	[]	[]	6	hSpCas9	negative selection	3452013
5314024	5314047	20	-	26780180	HT29	viability (Avana library 4 designs)	CTTCGAGATGGACTACTACGTGG	PROKR2	ENSG00000101292	-0.60352501433904	[]	[]	-8	hSpCas9	negative selection	3452014
5314063	5314086	20	-	26780180	HT29	viability (Avana library 4 designs)	GGCCATCTCCGACTTCCTGGTGG	PROKR2	ENSG00000101292	0.767493646676815	[]	[]	3	hSpCas9	negative selection	3452015
5314258	5314281	20	-	26780180	HT29	viability (Avana library 4 designs)	TGGTGATTATGACCTCCCTATGG	PROKR2	ENSG00000101292	-0.153123368968139	[]	[]	-2	hSpCas9	negative selection	3452016
5314258	5314281	20	-	26780180	A375	viability (Avana lentiCRISPRv2)	TGGTGATTATGACCTCCCTATGG	PROKR2	ENSG00000101292	2.54231975239519	[]	[]	4	hSpCas9	negative selection	3548180
5314024	5314047	20	-	26780180	A375	viability (Avana lentiCRISPRv2)	CTTCGAGATGGACTACTACGTGG	PROKR2	ENSG00000101292	3.96734000157705	[]	[]	6	hSpCas9	negative selection	3548181
5314027	5314050	20	+	26780180	A375	viability (Avana lentiCRISPRv2)	CGTAGTAGTCCATCTCGAAGGGG	PROKR2	ENSG00000101292	2.28380546255791	[]	[]	3	hSpCas9	negative selection	3548182
5314063	5314086	20	-	26780180	A375	viability (Avana lentiCRISPRv2)	GGCCATCTCCGACTTCCTGGTGG	PROKR2	ENSG00000101292	-0.66908767713976	[]	[]	-1	hSpCas9	negative selection	3548183
5302703	5302726	20	-	26780180	A375	viability (Avana lentiCRISPRv2)	TCGTTCACCCCTTGAAACCACGG	PROKR2	ENSG00000101292	-2.28675146932199	[]	[]	-3	hSpCas9	negative selection	3548184
5302686	5302709	20	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCCGTTTGATAATTCATCCGTGG	PROKR2	ENSG00000101292	2.05039412190223	[]	[]	3	hSpCas9	negative selection	3548185
5314258	5314281	20	-	26780180	A375	viability (Avana lentiGuide)	TGGTGATTATGACCTCCCTATGG	PROKR2	ENSG00000101292	-0.262504020769229	[]	[]	0	hSpCas9	negative selection	3656839
5314024	5314047	20	-	26780180	A375	viability (Avana lentiGuide)	CTTCGAGATGGACTACTACGTGG	PROKR2	ENSG00000101292	-4.9526351940649	[]	[]	-8	hSpCas9	negative selection	3656840
5314027	5314050	20	+	26780180	A375	viability (Avana lentiGuide)	CGTAGTAGTCCATCTCGAAGGGG	PROKR2	ENSG00000101292	30.161456639108	[]	[]	9	hSpCas9	negative selection	3656841
5314063	5314086	20	-	26780180	A375	viability (Avana lentiGuide)	GGCCATCTCCGACTTCCTGGTGG	PROKR2	ENSG00000101292	5.0189615737867	[]	[]	4	hSpCas9	negative selection	3656842
5302703	5302726	20	-	26780180	A375	viability (Avana lentiGuide)	TCGTTCACCCCTTGAAACCACGG	PROKR2	ENSG00000101292	3.9660698194609	[]	[]	4	hSpCas9	negative selection	3656843
5302686	5302709	20	+	26780180	A375	viability (Avana lentiGuide)	GCCGTTTGATAATTCATCCGTGG	PROKR2	ENSG00000101292	-3.08510435091855	[]	[]	-5	hSpCas9	negative selection	3656844
5314258	5314281	20	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TGGTGATTATGACCTCCCTATGG	PROKR2	ENSG00000101292	-0.048800777308508875	[5]	[5,4]	-1	hSpCas9	positive selection	3765446
5314024	5314047	20	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CTTCGAGATGGACTACTACGTGG	PROKR2	ENSG00000101292	0.0972804860758626	[5]	[6,5]	2	hSpCas9	positive selection	3765447
5314027	5314050	20	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CGTAGTAGTCCATCTCGAAGGGG	PROKR2	ENSG00000101292	-0.07559542141044454	[4]	[5,3]	-1	hSpCas9	positive selection	3765448
5314063	5314086	20	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGCCATCTCCGACTTCCTGGTGG	PROKR2	ENSG00000101292	-0.1600306471976853	[4]	[4,3]	-3	hSpCas9	positive selection	3765449
5302703	5302726	20	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TCGTTCACCCCTTGAAACCACGG	PROKR2	ENSG00000101292	-0.2033582170237957	[4]	[4,3]	-3	hSpCas9	positive selection	3765450
5302686	5302709	20	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCCGTTTGATAATTCATCCGTGG	PROKR2	ENSG00000101292	0.1921503779233181	[5]	[5,5]	5	hSpCas9	positive selection	3765451
5314258	5314281	20	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TGGTGATTATGACCTCCCTATGG	PROKR2	ENSG00000101292	-0.0948568619569138	[5]	[3,5]	-1	hSpCas9	positive selection	3874053
5314024	5314047	20	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CTTCGAGATGGACTACTACGTGG	PROKR2	ENSG00000101292	0.1593912281425523	[6]	[6,5]	4	hSpCas9	positive selection	3874054
5314027	5314050	20	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CGTAGTAGTCCATCTCGAAGGGG	PROKR2	ENSG00000101292	-0.9348739388454601	[4]	[0,2]	-8	hSpCas9	positive selection	3874055
5314063	5314086	20	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGCCATCTCCGACTTCCTGGTGG	PROKR2	ENSG00000101292	0.08591785243977872	[5]	[4,4]	2	hSpCas9	positive selection	3874056
5302703	5302726	20	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TCGTTCACCCCTTGAAACCACGG	PROKR2	ENSG00000101292	-0.040203126836293485	[5]	[4,5]	0	hSpCas9	positive selection	3874057
5302686	5302709	20	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCCGTTTGATAATTCATCCGTGG	PROKR2	ENSG00000101292	-0.22270654785001257	[4]	[2,4]	-3	hSpCas9	positive selection	3874058
5302232	5302255	20	+	26780180	A375	viability	GATGCACTCGACCACGTAGAAGG	PROKR2	ENSG00000101292	1.12980139796617	[]	[]	5	hSpCas9	negative selection	3984520
5302686	5302709	20	+	26780180	A375	viability	GCCGTTTGATAATTCATCCGTGG	PROKR2	ENSG00000101292	0.922260262577545	[]	[]	4	hSpCas9	negative selection	3984521
5314111	5314134	20	+	26780180	A375	viability	GGTTGCGCAACTTCTTATAGCGG	PROKR2	ENSG00000101292	0.352020353052688	[]	[]	0	hSpCas9	negative selection	3984522
5314193	5314216	20	+	26780180	A375	viability	TGCAATGCCAATGACGATCTTGG	PROKR2	ENSG00000101292	0.685001631840369	[]	[]	2	hSpCas9	negative selection	3984523
5314217	5314240	20	+	26780180	A375	viability	TGCGAAGAAGGTCCGGGTCTTGG	PROKR2	ENSG00000101292	0.288521439172081	[]	[]	0	hSpCas9	negative selection	3984524
5314200	5314223	20	-	26780180	A375	viability	TTCGCAGCCAAGATCGTCATTGG	PROKR2	ENSG00000101292	1.00303484546147	[]	[]	4	hSpCas9	negative selection	3984525
5302232	5302255	20	+	26780180	HT29	viability (GeCKOv2 library)	GATGCACTCGACCACGTAGAAGG	PROKR2	ENSG00000101292	0.593700920172394	[]	[]	2	hSpCas9	negative selection	4092486
5302686	5302709	20	+	26780180	HT29	viability (GeCKOv2 library)	GCCGTTTGATAATTCATCCGTGG	PROKR2	ENSG00000101292	1.23589826892269	[]	[]	6	hSpCas9	negative selection	4092487
5314111	5314134	20	+	26780180	HT29	viability (GeCKOv2 library)	GGTTGCGCAACTTCTTATAGCGG	PROKR2	ENSG00000101292	0.824977989809062	[]	[]	3	hSpCas9	negative selection	4092488
5314193	5314216	20	+	26780180	HT29	viability (GeCKOv2 library)	TGCAATGCCAATGACGATCTTGG	PROKR2	ENSG00000101292	0.81646452744335	[]	[]	3	hSpCas9	negative selection	4092489
5314217	5314240	20	+	26780180	HT29	viability (GeCKOv2 library)	TGCGAAGAAGGTCCGGGTCTTGG	PROKR2	ENSG00000101292	0.822032605784103	[]	[]	3	hSpCas9	negative selection	4092490
5314200	5314223	20	-	26780180	HT29	viability (GeCKOv2 library)	TTCGCAGCCAAGATCGTCATTGG	PROKR2	ENSG00000101292	0.914163626468975	[]	[]	4	hSpCas9	negative selection	4092491
5314007	5314030	20	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	ACGTGGTACGGCAGCTCTCCTGG	PROKR2	ENSG00000101292	-0.12572078546556467	[3]	[2,1]	-3	hSpCas9	positive selection	4163114
5302686	5302709	20	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GCCGTTTGATAATTCATCCGTGG	PROKR2	ENSG00000101292	-0.09108286965439168	[3]	[2,2]	-2	hSpCas9	positive selection	4163115
5314111	5314134	20	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GGTTGCGCAACTTCTTATAGCGG	PROKR2	ENSG00000101292	1.154644080588868	[1]	[4,0]	9	hSpCas9	positive selection	4163116
5302486	5302509	20	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TGTCGAGTTCGTGGGCCCTGTGG	PROKR2	ENSG00000101292	0.568091261577285	[3]	[2,4]	9	hSpCas9	positive selection	4163117
5314007	5314030	20	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	ACGTGGTACGGCAGCTCTCCTGG	PROKR2	ENSG00000101292	0.5411640452983468	[2]	[2,2,0,0]	4	hSpCas9	positive selection	4227136
5302686	5302709	20	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GCCGTTTGATAATTCATCCGTGG	PROKR2	ENSG00000101292	0.718817496489567	[2]	[2,2,4,0]	4	hSpCas9	positive selection	4227137
5314111	5314134	20	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GGTTGCGCAACTTCTTATAGCGG	PROKR2	ENSG00000101292	0.27898330953180983	[2]	[3,0,0,0]	2	hSpCas9	positive selection	4227138
5302486	5302509	20	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TGTCGAGTTCGTGGGCCCTGTGG	PROKR2	ENSG00000101292	-0.09427498301603954	[3]	[1,3,1,0]	-1	hSpCas9	positive selection	4227139
5314111	5314134	20	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GGTTGCGCAACTTCTTATAGCGG	PROKR2	ENSG00000101292	0.07309437892937287	[0]	[1,0]	1	hSpCas9	positive selection	4292308
5302686	5302709	20	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GCCGTTTGATAATTCATCCGTGG	PROKR2	ENSG00000101292	0.1376983412332979	[2]	[2,1]	2	hSpCas9	positive selection	4292309
5302232	5302255	20	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GATGCACTCGACCACGTAGAAGG	PROKR2	ENSG00000101292	-0.04016760831271553	[3]	[3,1]	-1	hSpCas9	positive selection	4292310
5314200	5314223	20	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TTCGCAGCCAAGATCGTCATTGG	PROKR2	ENSG00000101292	-0.13320887476821192	[4]	[3,1]	-3	hSpCas9	positive selection	4356567
5314217	5314240	20	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TGCGAAGAAGGTCCGGGTCTTGG	PROKR2	ENSG00000101292	0.11497363909500008	[2]	[2,2]	2	hSpCas9	positive selection	4356568
5314193	5314216	20	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TGCAATGCCAATGACGATCTTGG	PROKR2	ENSG00000101292	0.02602579774263397	[4]	[3,2]	0	hSpCas9	positive selection	4356569
5302616	5302638	20	+	27760321	OCIAML3	viability	TGTTGCAAAGTAAGCCGATGGG	PROKR2	ENSG00000101292	-0.09498390116001532	[308,242]	[172,236]	-1	hSpCas9	negative selection	4430800
5302630	5302652	20	-	27760321	OCIAML3	viability	ATTCTCATTGCCATCCCATCGG	PROKR2	ENSG00000101292	0.164777106601788	[400,430]	[277,482]	2	hSpCas9	negative selection	4430801
5302687	5302709	20	+	27760321	OCIAML3	viability	CCGTTTGATAATTCATCCGTGG	PROKR2	ENSG00000101292	0.370484606210099	[531,456]	[514,476]	4	hSpCas9	negative selection	4430802
5314118	5314140	20	+	27760321	OCIAML3	viability	CAACTTCTTATAGCGGGTGAGG	PROKR2	ENSG00000101292	-0.021353728520560722	[734,569]	[434,582]	0	hSpCas9	negative selection	4430803
5314258	5314280	20	-	27760321	OCIAML3	viability	GGTGATTATGACCTCCCTATGG	PROKR2	ENSG00000101292	1.0101282533907312	[248,244]	[337,457]	9	hSpCas9	negative selection	4430804
5302616	5302638	20	+	27760321	OCIAML2	viability	TGTTGCAAAGTAAGCCGATGGG	PROKR2	ENSG00000101292	0.39032049714734973	[308,242]	[225,375]	5	hSpCas9	negative selection	4514263
5302630	5302652	20	-	27760321	OCIAML2	viability	ATTCTCATTGCCATCCCATCGG	PROKR2	ENSG00000101292	-0.05893766983981061	[400,430]	[230,448]	-1	hSpCas9	negative selection	4514264
5302687	5302709	20	+	27760321	OCIAML2	viability	CCGTTTGATAATTCATCCGTGG	PROKR2	ENSG00000101292	-0.11043005342281095	[531,456]	[384,348]	-1	hSpCas9	negative selection	4514265
5314118	5314140	20	+	27760321	OCIAML2	viability	CAACTTCTTATAGCGGGTGAGG	PROKR2	ENSG00000101292	0.8000160288894856	[734,569]	[710,1177]	9	hSpCas9	negative selection	4514266
5314258	5314280	20	-	27760321	OCIAML2	viability	GGTGATTATGACCTCCCTATGG	PROKR2	ENSG00000101292	0.2079481371617692	[248,244]	[214,252]	2	hSpCas9	negative selection	4514267
5302616	5302638	20	+	27760321	MV411	viability	TGTTGCAAAGTAAGCCGATGGG	PROKR2	ENSG00000101292	-1.541689489680289	[308,242]	[2,150]	-7	hSpCas9	negative selection	4597726
5302630	5302652	20	-	27760321	MV411	viability	ATTCTCATTGCCATCCCATCGG	PROKR2	ENSG00000101292	0.8338330667367729	[400,430]	[445,561]	6	hSpCas9	negative selection	4597727
5302687	5302709	20	+	27760321	MV411	viability	CCGTTTGATAATTCATCCGTGG	PROKR2	ENSG00000101292	0.19183134656873901	[531,456]	[168,675]	1	hSpCas9	negative selection	4597728
5314118	5314140	20	+	27760321	MV411	viability	CAACTTCTTATAGCGGGTGAGG	PROKR2	ENSG00000101292	0.2346358024340569	[734,569]	[546,436]	1	hSpCas9	negative selection	4597729
5314258	5314280	20	-	27760321	MV411	viability	GGTGATTATGACCTCCCTATGG	PROKR2	ENSG00000101292	0.02450682354931688	[248,244]	[192,125]	0	hSpCas9	negative selection	4597730
5302616	5302638	20	+	27760321	HL60	viability	TGTTGCAAAGTAAGCCGATGGG	PROKR2	ENSG00000101292	-0.1851808496494698	[308,242]	[163,231]	-2	hSpCas9	negative selection	4681189
5302630	5302652	20	-	27760321	HL60	viability	ATTCTCATTGCCATCCCATCGG	PROKR2	ENSG00000101292	0.6795172305511268	[400,430]	[585,506]	7	hSpCas9	negative selection	4681190
5302687	5302709	20	+	27760321	HL60	viability	CCGTTTGATAATTCATCCGTGG	PROKR2	ENSG00000101292	-0.5473019980273308	[531,456]	[245,306]	-5	hSpCas9	negative selection	4681191
5314118	5314140	20	+	27760321	HL60	viability	CAACTTCTTATAGCGGGTGAGG	PROKR2	ENSG00000101292	0.6412282174006095	[734,569]	[888,757]	7	hSpCas9	negative selection	4681192
5314258	5314280	20	-	27760321	HL60	viability	GGTGATTATGACCTCCCTATGG	PROKR2	ENSG00000101292	-0.6722661395364975	[248,244]	[91,163]	-6	hSpCas9	negative selection	4681193
5302616	5302638	20	+	27760321	HT1080	viability	TGTTGCAAAGTAAGCCGATGGG	PROKR2	ENSG00000101292	1.3815797765054776	[242,189]	[113,345]	7	hSpCas9	negative selection	4764652
5302630	5302652	20	-	27760321	HT1080	viability	ATTCTCATTGCCATCCCATCGG	PROKR2	ENSG00000101292	-0.9862211321112342	[430,336]	[60,94]	-4	hSpCas9	negative selection	4764653
5302687	5302709	20	+	27760321	HT1080	viability	CCGTTTGATAATTCATCCGTGG	PROKR2	ENSG00000101292	0.4672816410286044	[456,356]	[311,127]	2	hSpCas9	negative selection	4764654
5314118	5314140	20	+	27760321	HT1080	viability	CAACTTCTTATAGCGGGTGAGG	PROKR2	ENSG00000101292	0.7575255534309511	[569,444]	[326,357]	4	hSpCas9	negative selection	4764655
5314258	5314280	20	-	27760321	HT1080	viability	GGTGATTATGACCTCCCTATGG	PROKR2	ENSG00000101292	0.45395876902324667	[244,190]	[138,96]	2	hSpCas9	negative selection	4764656
5302616	5302638	20	+	27760321	HT29	viability after 7 days	TGTTGCAAAGTAAGCCGATGGG	PROKR2	ENSG00000101292	-0.6809912586768463	[242,189]	[155,119,239]	-7	hSpCas9	negative selection	4848115
5302630	5302652	20	-	27760321	HT29	viability after 7 days	ATTCTCATTGCCATCCCATCGG	PROKR2	ENSG00000101292	-0.12201401214563086	[430,336]	[479,421,461]	-2	hSpCas9	negative selection	4848116
5302687	5302709	20	+	27760321	HT29	viability after 7 days	CCGTTTGATAATTCATCCGTGG	PROKR2	ENSG00000101292	-0.06655753005800528	[456,356]	[324,504,638]	-1	hSpCas9	negative selection	4848117
5314118	5314140	20	+	27760321	HT29	viability after 7 days	CAACTTCTTATAGCGGGTGAGG	PROKR2	ENSG00000101292	0.2875428750890573	[569,444]	[874,907,621]	4	hSpCas9	negative selection	4848118
5314258	5314280	20	-	27760321	HT29	viability after 7 days	GGTGATTATGACCTCCCTATGG	PROKR2	ENSG00000101292	0.31205931344184296	[244,190]	[352,277,410]	5	hSpCas9	negative selection	4848119
5302616	5302638	20	+	27760321	HT29	viability after 25 days	TGTTGCAAAGTAAGCCGATGGG	PROKR2	ENSG00000101292	-0.032205151827793155	[242,189]	[355,235,112]	0	hSpCas9	negative selection	4931578
5302630	5302652	20	-	27760321	HT29	viability after 25 days	ATTCTCATTGCCATCCCATCGG	PROKR2	ENSG00000101292	-0.050037153050271545	[430,336]	[236,405,664]	0	hSpCas9	negative selection	4931579
5302687	5302709	20	+	27760321	HT29	viability after 25 days	CCGTTTGATAATTCATCCGTGG	PROKR2	ENSG00000101292	0.2029370155835729	[456,356]	[565,402,645]	2	hSpCas9	negative selection	4931580
5314118	5314140	20	+	27760321	HT29	viability after 25 days	CAACTTCTTATAGCGGGTGAGG	PROKR2	ENSG00000101292	0.4317596525067001	[569,444]	[900,571,874]	5	hSpCas9	negative selection	4931581
5314258	5314280	20	-	27760321	HT29	viability after 25 days	GGTGATTATGACCTCCCTATGG	PROKR2	ENSG00000101292	0.45651463097881556	[244,190]	[519,244,237]	5	hSpCas9	negative selection	4931582
5302616	5302638	20	+	27760321	HT29	viability after 22 days	TGTTGCAAAGTAAGCCGATGGG	PROKR2	ENSG00000101292	-0.2534462688673016	[242,189]	[230,227,169]	-3	hSpCas9	negative selection	5015041
5302630	5302652	20	-	27760321	HT29	viability after 22 days	ATTCTCATTGCCATCCCATCGG	PROKR2	ENSG00000101292	-0.41098504338055253	[430,336]	[228,396,378]	-4	hSpCas9	negative selection	5015042
5302687	5302709	20	+	27760321	HT29	viability after 22 days	CCGTTTGATAATTCATCCGTGG	PROKR2	ENSG00000101292	0.3197419387833907	[456,356]	[555,584,621]	3	hSpCas9	negative selection	5015043
5314118	5314140	20	+	27760321	HT29	viability after 22 days	CAACTTCTTATAGCGGGTGAGG	PROKR2	ENSG00000101292	0.47872393745533637	[569,444]	[1051,824,566]	5	hSpCas9	negative selection	5015044
5314258	5314280	20	-	27760321	HT29	viability after 22 days	GGTGATTATGACCTCCCTATGG	PROKR2	ENSG00000101292	0.1657222155185335	[244,190]	[333,295,215]	1	hSpCas9	negative selection	5015045
5302616	5302638	20	+	27760321	HT29	viability after 19 days	TGTTGCAAAGTAAGCCGATGGG	PROKR2	ENSG00000101292	0.35280940511939085	[242,189]	[331,136,474]	3	hSpCas9	negative selection	5098504
5302630	5302652	20	-	27760321	HT29	viability after 19 days	ATTCTCATTGCCATCCCATCGG	PROKR2	ENSG00000101292	-0.4153248410928062	[430,336]	[535,238,237]	-4	hSpCas9	negative selection	5098505
5302687	5302709	20	+	27760321	HT29	viability after 19 days	CCGTTTGATAATTCATCCGTGG	PROKR2	ENSG00000101292	0.4653325880628551	[456,356]	[922,525,512]	4	hSpCas9	negative selection	5098506
5314118	5314140	20	+	27760321	HT29	viability after 19 days	CAACTTCTTATAGCGGGTGAGG	PROKR2	ENSG00000101292	0.17044083261098686	[569,444]	[975,390,626]	1	hSpCas9	negative selection	5098507
5314258	5314280	20	-	27760321	HT29	viability after 19 days	GGTGATTATGACCTCCCTATGG	PROKR2	ENSG00000101292	1.2846943981366357	[244,190]	[668,814,353]	9	hSpCas9	negative selection	5098508
5302616	5302638	20	+	27760321	HT29	viability after 16 days	TGTTGCAAAGTAAGCCGATGGG	PROKR2	ENSG00000101292	0.3495713326149875	[242,189]	[411,182,343]	4	hSpCas9	negative selection	5181967
5302630	5302652	20	-	27760321	HT29	viability after 16 days	ATTCTCATTGCCATCCCATCGG	PROKR2	ENSG00000101292	-0.2622887464970529	[430,336]	[443,272,367]	-3	hSpCas9	negative selection	5181968
5302687	5302709	20	+	27760321	HT29	viability after 16 days	CCGTTTGATAATTCATCCGTGG	PROKR2	ENSG00000101292	0.06878571659295085	[456,356]	[582,428,431]	0	hSpCas9	negative selection	5181969
5314118	5314140	20	+	27760321	HT29	viability after 16 days	CAACTTCTTATAGCGGGTGAGG	PROKR2	ENSG00000101292	0.6112792061386765	[569,444]	[1113,572,945]	7	hSpCas9	negative selection	5181970
5314258	5314280	20	-	27760321	HT29	viability after 16 days	GGTGATTATGACCTCCCTATGG	PROKR2	ENSG00000101292	0.029623719532367532	[244,190]	[299,233,217]	0	hSpCas9	negative selection	5181971
5302616	5302638	20	+	27760321	HT29	viability after 13 days	TGTTGCAAAGTAAGCCGATGGG	PROKR2	ENSG00000101292	-0.015904963743366918	[242,189]	[292,200,250]	0	hSpCas9	negative selection	5265430
5302630	5302652	20	-	27760321	HT29	viability after 13 days	ATTCTCATTGCCATCCCATCGG	PROKR2	ENSG00000101292	-0.05067330119542467	[430,336]	[453,553,290]	0	hSpCas9	negative selection	5265431
5302687	5302709	20	+	27760321	HT29	viability after 13 days	CCGTTTGATAATTCATCCGTGG	PROKR2	ENSG00000101292	0.09595775490342945	[456,356]	[551,562,404]	1	hSpCas9	negative selection	5265432
5314118	5314140	20	+	27760321	HT29	viability after 13 days	CAACTTCTTATAGCGGGTGAGG	PROKR2	ENSG00000101292	0.42135573702155615	[569,444]	[830,657,870]	5	hSpCas9	negative selection	5265433
5314258	5314280	20	-	27760321	HT29	viability after 13 days	GGTGATTATGACCTCCCTATGG	PROKR2	ENSG00000101292	0.46323319002168684	[244,190]	[508,196,339]	6	hSpCas9	negative selection	5265434
5302616	5302638	20	+	27760321	HT29	viability after 10 days	TGTTGCAAAGTAAGCCGATGGG	PROKR2	ENSG00000101292	-0.1049586069296986	[242,189]	[196,213,339]	-1	hSpCas9	negative selection	5348893
5302630	5302652	20	-	27760321	HT29	viability after 10 days	ATTCTCATTGCCATCCCATCGG	PROKR2	ENSG00000101292	-0.006143891788172248	[430,336]	[385,411,628]	0	hSpCas9	negative selection	5348894
5302687	5302709	20	+	27760321	HT29	viability after 10 days	CCGTTTGATAATTCATCCGTGG	PROKR2	ENSG00000101292	-0.08727393092330743	[456,356]	[469,441,520]	-1	hSpCas9	negative selection	5348895
5314118	5314140	20	+	27760321	HT29	viability after 10 days	CAACTTCTTATAGCGGGTGAGG	PROKR2	ENSG00000101292	0.2956389417697245	[569,444]	[1008,670,652]	4	hSpCas9	negative selection	5348896
5314258	5314280	20	-	27760321	HT29	viability after 10 days	GGTGATTATGACCTCCCTATGG	PROKR2	ENSG00000101292	0.07233804514233699	[244,190]	[436,229,191]	0	hSpCas9	negative selection	5348897
5302616	5302638	20	+	27760321	MOLM13	viability	TGTTGCAAAGTAAGCCGATGGG	PROKR2	ENSG00000101292	0.7643704807065166	[308,242]	[332,202]	5	hSpCas9	negative selection	5432356
5302630	5302652	20	-	27760321	MOLM13	viability	ATTCTCATTGCCATCCCATCGG	PROKR2	ENSG00000101292	-0.8127390037843788	[400,430]	[161,110]	-5	hSpCas9	negative selection	5432357
5302687	5302709	20	+	27760321	MOLM13	viability	CCGTTTGATAATTCATCCGTGG	PROKR2	ENSG00000101292	-0.9450167075333988	[531,456]	[110,172]	-5	hSpCas9	negative selection	5432358
5314118	5314140	20	+	27760321	MOLM13	viability	CAACTTCTTATAGCGGGTGAGG	PROKR2	ENSG00000101292	-0.7543728759831447	[734,569]	[267,172]	-5	hSpCas9	negative selection	5432359
5314258	5314280	20	-	27760321	MOLM13	viability	GGTGATTATGACCTCCCTATGG	PROKR2	ENSG00000101292	1.306647465699179	[248,244]	[0,638]	8	hSpCas9	negative selection	5432360
5314111	5314134	20	+	27260156	BXPC3	viability	GGTTGCGCAACTTCTTATAGCGG	PROKR2	ENSG00000101292	-0.41190491915160177	[65]	[39,53,49,65]	-7	hSpCas9	negative selection	5564768
5302686	5302709	20	+	27260156	BXPC3	viability	GCCGTTTGATAATTCATCCGTGG	PROKR2	ENSG00000101292	-0.2444632868354616	[274]	[166,263,214,341]	-5	hSpCas9	negative selection	5564769
5302232	5302255	20	+	27260156	BXPC3	viability	GATGCACTCGACCACGTAGAAGG	PROKR2	ENSG00000101292	-0.355588334135052	[657]	[491,513,492,669]	-7	hSpCas9	negative selection	5564770
5314200	5314223	20	-	27260156	BXPC3	viability	TTCGCAGCCAAGATCGTCATTGG	PROKR2	ENSG00000101292	-0.4437089694351134	[1221]	[1067,859,924,880]	-7	hSpCas9	negative selection	5629027
5314217	5314240	20	+	27260156	BXPC3	viability	TGCGAAGAAGGTCCGGGTCTTGG	PROKR2	ENSG00000101292	0.32072294803982193	[416]	[425,685,475,595]	7	hSpCas9	negative selection	5629028
5314193	5314216	20	+	27260156	BXPC3	viability	TGCAATGCCAATGACGATCTTGG	PROKR2	ENSG00000101292	-0.3212012380824366	[1016]	[791,859,845,913]	-6	hSpCas9	negative selection	5629029
5314111	5314134	20	+	27260156	A673	viability	GGTTGCGCAACTTCTTATAGCGG	PROKR2	ENSG00000101292	-0.14383578185846924	[65]	[77,60,72,75]	-4	hSpCas9	negative selection	5686019
5302686	5302709	20	+	27260156	A673	viability	GCCGTTTGATAATTCATCCGTGG	PROKR2	ENSG00000101292	0.03618002884206106	[274]	[388,335,309,323]	0	hSpCas9	negative selection	5686020
5302232	5302255	20	+	27260156	A673	viability	GATGCACTCGACCACGTAGAAGG	PROKR2	ENSG00000101292	-0.20116849231077644	[657]	[722,590,659,785]	-5	hSpCas9	negative selection	5686021
5314200	5314223	20	-	27260156	A673	viability	TTCGCAGCCAAGATCGTCATTGG	PROKR2	ENSG00000101292	-0.32884004983105375	[1221]	[1259,1049,1101,1278]	-7	hSpCas9	negative selection	5750278
5314217	5314240	20	+	27260156	A673	viability	TGCGAAGAAGGTCCGGGTCTTGG	PROKR2	ENSG00000101292	0.45369406644444	[416]	[669,573,731,770]	8	hSpCas9	negative selection	5750279
5314193	5314216	20	+	27260156	A673	viability	TGCAATGCCAATGACGATCTTGG	PROKR2	ENSG00000101292	-0.20498706024663715	[1016]	[1299,1069,922,965]	-5	hSpCas9	negative selection	5750280
5314111	5314134	20	+	27260156	A375	viability	GGTTGCGCAACTTCTTATAGCGG	PROKR2	ENSG00000101292	-0.15177615666853983	[65]	[34,50,49,130]	-2	hSpCas9	negative selection	5807270
5302686	5302709	20	+	27260156	A375	viability	GCCGTTTGATAATTCATCCGTGG	PROKR2	ENSG00000101292	-0.02459307579251324	[274]	[312,428,306,237]	0	hSpCas9	negative selection	5807271
5302232	5302255	20	+	27260156	A375	viability	GATGCACTCGACCACGTAGAAGG	PROKR2	ENSG00000101292	-0.10713990514132177	[657]	[603,800,746,710]	-1	hSpCas9	negative selection	5807272
5314200	5314223	20	-	27260156	A375	viability	TTCGCAGCCAAGATCGTCATTGG	PROKR2	ENSG00000101292	-0.34585970157713963	[1221]	[1169,1346,1153,877]	-5	hSpCas9	negative selection	5871529
5314217	5314240	20	+	27260156	A375	viability	TGCGAAGAAGGTCCGGGTCTTGG	PROKR2	ENSG00000101292	0.3535918779754568	[416]	[455,767,641,637]	5	hSpCas9	negative selection	5871530
5314193	5314216	20	+	27260156	A375	viability	TGCAATGCCAATGACGATCTTGG	PROKR2	ENSG00000101292	0.11639399136963569	[1016]	[1186,1331,1251,1369]	1	hSpCas9	negative selection	5871531
5314111	5314134	20	+	27260156	COLO741	viability	GGTTGCGCAACTTCTTATAGCGG	PROKR2	ENSG00000101292	-0.16756217435290388	[65]	[35,98,85]	-4	hSpCas9	negative selection	5928521
5302686	5302709	20	+	27260156	COLO741	viability	GCCGTTTGATAATTCATCCGTGG	PROKR2	ENSG00000101292	-0.30459577077530475	[274]	[387,252,224]	-6	hSpCas9	negative selection	5928522
5302232	5302255	20	+	27260156	COLO741	viability	GATGCACTCGACCACGTAGAAGG	PROKR2	ENSG00000101292	0.27735038236290344	[657]	[1164,1124,793]	6	hSpCas9	negative selection	5928523
5314200	5314223	20	-	27260156	COLO741	viability	TTCGCAGCCAAGATCGTCATTGG	PROKR2	ENSG00000101292	-0.31031910198642665	[1221]	[1385,1206,1196]	-6	hSpCas9	negative selection	5992780
5314217	5314240	20	+	27260156	COLO741	viability	TGCGAAGAAGGTCCGGGTCTTGG	PROKR2	ENSG00000101292	0.3900322069854299	[416]	[951,588,581]	7	hSpCas9	negative selection	5992781
5314193	5314216	20	+	27260156	COLO741	viability	TGCAATGCCAATGACGATCTTGG	PROKR2	ENSG00000101292	-0.06747899030453608	[1016]	[1366,1275,1095]	-1	hSpCas9	negative selection	5992782
5314111	5314134	20	+	27260156	CAL120	viability	GGTTGCGCAACTTCTTATAGCGG	PROKR2	ENSG00000101292	0.8320657520141803	[65]	[182,164,96]	9	hSpCas9	negative selection	6049772
5302686	5302709	20	+	27260156	CAL120	viability	GCCGTTTGATAATTCATCCGTGG	PROKR2	ENSG00000101292	-0.20535124352065526	[274]	[392,283,228]	-3	hSpCas9	negative selection	6049773
5302232	5302255	20	+	27260156	CAL120	viability	GATGCACTCGACCACGTAGAAGG	PROKR2	ENSG00000101292	0.18787505047642206	[657]	[778,807,1182]	3	hSpCas9	negative selection	6049774
5314200	5314223	20	-	27260156	CAL120	viability	TTCGCAGCCAAGATCGTCATTGG	PROKR2	ENSG00000101292	-0.06170508988530399	[1221]	[1898,1593,952]	-1	hSpCas9	negative selection	6114031
5314217	5314240	20	+	27260156	CAL120	viability	TGCGAAGAAGGTCCGGGTCTTGG	PROKR2	ENSG00000101292	0.41443864916361706	[416]	[746,653,681]	6	hSpCas9	negative selection	6114032
5314193	5314216	20	+	27260156	CAL120	viability	TGCAATGCCAATGACGATCTTGG	PROKR2	ENSG00000101292	0.10453436432807228	[1016]	[1194,1475,1384]	1	hSpCas9	negative selection	6114033
5314111	5314134	20	+	27260156	CADOES1	viability	GGTTGCGCAACTTCTTATAGCGG	PROKR2	ENSG00000101292	0.6660984076651992	[65]	[37,180,71,98]	9	hSpCas9	negative selection	6171023
5302686	5302709	20	+	27260156	CADOES1	viability	GCCGTTTGATAATTCATCCGTGG	PROKR2	ENSG00000101292	-0.16998387132008808	[274]	[144,267,310,183]	-3	hSpCas9	negative selection	6171024
5302232	5302255	20	+	27260156	CADOES1	viability	GATGCACTCGACCACGTAGAAGG	PROKR2	ENSG00000101292	-0.17917442279451118	[657]	[623,717,412,401]	-3	hSpCas9	negative selection	6171025
5314200	5314223	20	-	27260156	CADOES1	viability	TTCGCAGCCAAGATCGTCATTGG	PROKR2	ENSG00000101292	-0.33268398489616025	[1221]	[894,832,717,1173]	-5	hSpCas9	negative selection	6235282
5314217	5314240	20	+	27260156	CADOES1	viability	TGCGAAGAAGGTCCGGGTCTTGG	PROKR2	ENSG00000101292	0.5453513272603658	[416]	[482,621,651,504]	8	hSpCas9	negative selection	6235283
5314193	5314216	20	+	27260156	CADOES1	viability	TGCAATGCCAATGACGATCTTGG	PROKR2	ENSG00000101292	-0.18446598074863718	[1016]	[780,945,661,944]	-3	hSpCas9	negative selection	6235284
5314111	5314134	20	+	27260156	EWS502	viability	GGTTGCGCAACTTCTTATAGCGG	PROKR2	ENSG00000101292	0.26945029313946733	[65]	[57,48,74,164]	5	hSpCas9	negative selection	6292274
5302686	5302709	20	+	27260156	EWS502	viability	GCCGTTTGATAATTCATCCGTGG	PROKR2	ENSG00000101292	0.07385723709386616	[274]	[297,291,427,202]	1	hSpCas9	negative selection	6292275
5302232	5302255	20	+	27260156	EWS502	viability	GATGCACTCGACCACGTAGAAGG	PROKR2	ENSG00000101292	0.18031776657209242	[657]	[450,850,911,996]	3	hSpCas9	negative selection	6292276
5314200	5314223	20	-	27260156	EWS502	viability	TTCGCAGCCAAGATCGTCATTGG	PROKR2	ENSG00000101292	-0.2773161720426509	[1221]	[945,927,1384,1030]	-5	hSpCas9	negative selection	6356533
5314217	5314240	20	+	27260156	EWS502	viability	TGCGAAGAAGGTCCGGGTCTTGG	PROKR2	ENSG00000101292	0.34996381819557243	[416]	[478,577,610,593]	6	hSpCas9	negative selection	6356534
5314193	5314216	20	+	27260156	EWS502	viability	TGCAATGCCAATGACGATCTTGG	PROKR2	ENSG00000101292	0.134439392111952	[1016]	[1163,1181,1189,1191]	2	hSpCas9	negative selection	6356535
5314111	5314134	20	+	27260156	EW8	viability	GGTTGCGCAACTTCTTATAGCGG	PROKR2	ENSG00000101292	-0.25978927471516666	[65]	[80,8,40,51]	-5	hSpCas9	negative selection	6413525
5302686	5302709	20	+	27260156	EW8	viability	GCCGTTTGATAATTCATCCGTGG	PROKR2	ENSG00000101292	-0.20709134857824496	[274]	[374,161,84,187]	-4	hSpCas9	negative selection	6413526
5302232	5302255	20	+	27260156	EW8	viability	GATGCACTCGACCACGTAGAAGG	PROKR2	ENSG00000101292	-0.2208571499891192	[657]	[592,419,450,380]	-4	hSpCas9	negative selection	6413527
5314200	5314223	20	-	27260156	EW8	viability	TTCGCAGCCAAGATCGTCATTGG	PROKR2	ENSG00000101292	-0.47436382826428003	[1221]	[714,830,690,616]	-7	hSpCas9	negative selection	6477784
5314217	5314240	20	+	27260156	EW8	viability	TGCGAAGAAGGTCCGGGTCTTGG	PROKR2	ENSG00000101292	0.275317968266792	[416]	[418,417,342,466]	5	hSpCas9	negative selection	6477785
5314193	5314216	20	+	27260156	EW8	viability	TGCAATGCCAATGACGATCTTGG	PROKR2	ENSG00000101292	-0.21030320031251248	[1016]	[672,718,760,681]	-4	hSpCas9	negative selection	6477786
5314111	5314134	20	+	27260156	CORL105	viability	GGTTGCGCAACTTCTTATAGCGG	PROKR2	ENSG00000101292	-0.20295421544899117	[65]	[43,77,76,69]	-4	hSpCas9	negative selection	6534776
5302686	5302709	20	+	27260156	CORL105	viability	GCCGTTTGATAATTCATCCGTGG	PROKR2	ENSG00000101292	-0.4926862095535226	[274]	[262,178,264,215]	-7	hSpCas9	negative selection	6534777
5302232	5302255	20	+	27260156	CORL105	viability	GATGCACTCGACCACGTAGAAGG	PROKR2	ENSG00000101292	0.09001608512032022	[657]	[903,690,1003,714]	1	hSpCas9	negative selection	6534778
5314200	5314223	20	-	27260156	CORL105	viability	TTCGCAGCCAAGATCGTCATTGG	PROKR2	ENSG00000101292	-0.393380387621748	[1221]	[1084,1058,1191,1036]	-6	hSpCas9	negative selection	6599035
5314217	5314240	20	+	27260156	CORL105	viability	TGCGAAGAAGGTCCGGGTCTTGG	PROKR2	ENSG00000101292	-0.031983312124114455	[416]	[506,454,519,435]	0	hSpCas9	negative selection	6599036
5314193	5314216	20	+	27260156	CORL105	viability	TGCAATGCCAATGACGATCTTGG	PROKR2	ENSG00000101292	-0.1419829265283763	[1016]	[1390,878,1080,979]	-3	hSpCas9	negative selection	6599037
5314111	5314134	20	+	27260156	HS294T	viability	GGTTGCGCAACTTCTTATAGCGG	PROKR2	ENSG00000101292	0.4001838051736688	[65]	[23,45,41,20]	5	hSpCas9	negative selection	6656027
5302686	5302709	20	+	27260156	HS294T	viability	GCCGTTTGATAATTCATCCGTGG	PROKR2	ENSG00000101292	-0.9742927143212828	[274]	[40,50,54,73]	-8	hSpCas9	negative selection	6656028
5302232	5302255	20	+	27260156	HS294T	viability	GATGCACTCGACCACGTAGAAGG	PROKR2	ENSG00000101292	0.23421051004927673	[657]	[200,431,333,220]	3	hSpCas9	negative selection	6656029
5314200	5314223	20	-	27260156	HS294T	viability	TTCGCAGCCAAGATCGTCATTGG	PROKR2	ENSG00000101292	-0.22115916293146776	[1221]	[319,368,477,473]	-3	hSpCas9	negative selection	6720286
5314217	5314240	20	+	27260156	HS294T	viability	TGCGAAGAAGGTCCGGGTCTTGG	PROKR2	ENSG00000101292	-0.617666806349414	[416]	[86,91,118,127]	-7	hSpCas9	negative selection	6720287
5314193	5314216	20	+	27260156	HS294T	viability	TGCAATGCCAATGACGATCTTGG	PROKR2	ENSG00000101292	-0.4903412119442955	[1016]	[270,205,295,362]	-6	hSpCas9	negative selection	6720288
5314111	5314134	20	+	27260156	HCC44	viability	GGTTGCGCAACTTCTTATAGCGG	PROKR2	ENSG00000101292	1.506173900550582	[65]	[625,23,114,131]	9	hSpCas9	negative selection	6777278
5302686	5302709	20	+	27260156	HCC44	viability	GCCGTTTGATAATTCATCCGTGG	PROKR2	ENSG00000101292	0.030215136114782326	[274]	[352,226,338,366]	0	hSpCas9	negative selection	6777279
5302232	5302255	20	+	27260156	HCC44	viability	GATGCACTCGACCACGTAGAAGG	PROKR2	ENSG00000101292	0.2217163023989943	[657]	[1010,614,1166,774]	3	hSpCas9	negative selection	6777280
5314200	5314223	20	-	27260156	HCC44	viability	TTCGCAGCCAAGATCGTCATTGG	PROKR2	ENSG00000101292	-0.2719493109101976	[1221]	[1141,902,1557,1073]	-4	hSpCas9	negative selection	6841537
5314217	5314240	20	+	27260156	HCC44	viability	TGCGAAGAAGGTCCGGGTCTTGG	PROKR2	ENSG00000101292	0.38408115059470227	[416]	[385,671,924,501]	6	hSpCas9	negative selection	6841538
5314193	5314216	20	+	27260156	HCC44	viability	TGCAATGCCAATGACGATCTTGG	PROKR2	ENSG00000101292	-0.3477736233078226	[1016]	[949,750,1029,923]	-5	hSpCas9	negative selection	6841539
5314111	5314134	20	+	27260156	G402	viability	GGTTGCGCAACTTCTTATAGCGG	PROKR2	ENSG00000101292	-0.25059218161863006	[65]	[65,3,116,78]	-3	hSpCas9	negative selection	6898529
5302686	5302709	20	+	27260156	G402	viability	GCCGTTTGATAATTCATCCGTGG	PROKR2	ENSG00000101292	-0.9091064178312201	[274]	[174,127,258,149]	-8	hSpCas9	negative selection	6898530
5302232	5302255	20	+	27260156	G402	viability	GATGCACTCGACCACGTAGAAGG	PROKR2	ENSG00000101292	0.08831048072792624	[657]	[801,848,1104,656]	1	hSpCas9	negative selection	6898531
5314200	5314223	20	-	27260156	G402	viability	TTCGCAGCCAAGATCGTCATTGG	PROKR2	ENSG00000101292	-0.3154853025898643	[1221]	[693,1407,1563,1067]	-4	hSpCas9	negative selection	6962788
5314217	5314240	20	+	27260156	G402	viability	TGCGAAGAAGGTCCGGGTCTTGG	PROKR2	ENSG00000101292	0.5834998023215949	[416]	[526,826,801,855]	7	hSpCas9	negative selection	6962789
5314193	5314216	20	+	27260156	G402	viability	TGCAATGCCAATGACGATCTTGG	PROKR2	ENSG00000101292	-0.10023466603929121	[1016]	[887,1708,753,1262]	-1	hSpCas9	negative selection	6962790
5314111	5314134	20	+	27260156	L33	viability	GGTTGCGCAACTTCTTATAGCGG	PROKR2	ENSG00000101292	0.8481298177412124	[65]	[184,40,40,122]	9	hSpCas9	negative selection	7019780
5302686	5302709	20	+	27260156	L33	viability	GCCGTTTGATAATTCATCCGTGG	PROKR2	ENSG00000101292	-0.20782319682983186	[274]	[229,88,134,289]	-5	hSpCas9	negative selection	7019781
5302232	5302255	20	+	27260156	L33	viability	GATGCACTCGACCACGTAGAAGG	PROKR2	ENSG00000101292	-0.12080921942489603	[657]	[508,291,419,533]	-3	hSpCas9	negative selection	7019782
5314200	5314223	20	-	27260156	L33	viability	TTCGCAGCCAAGATCGTCATTGG	PROKR2	ENSG00000101292	-0.09520592988851306	[1221]	[1291,433,682,1133]	-2	hSpCas9	negative selection	7084039
5314217	5314240	20	+	27260156	L33	viability	TGCGAAGAAGGTCCGGGTCTTGG	PROKR2	ENSG00000101292	-0.969045288806951	[416]	[306,78,125,149]	-9	hSpCas9	negative selection	7084040
5314193	5314216	20	+	27260156	L33	viability	TGCAATGCCAATGACGATCTTGG	PROKR2	ENSG00000101292	-0.19192294086604555	[1016]	[847,399,551,859]	-4	hSpCas9	negative selection	7084041
5314111	5314134	20	+	27260156	K562	viability	GGTTGCGCAACTTCTTATAGCGG	PROKR2	ENSG00000101292	0.4915911419820187	[65]	[40,138,31,112]	6	hSpCas9	negative selection	7141031
5302686	5302709	20	+	27260156	K562	viability	GCCGTTTGATAATTCATCCGTGG	PROKR2	ENSG00000101292	-0.5111714620878255	[274]	[247,197,103,144]	-6	hSpCas9	negative selection	7141032
5302232	5302255	20	+	27260156	K562	viability	GATGCACTCGACCACGTAGAAGG	PROKR2	ENSG00000101292	0.2932196275266198	[657]	[427,1075,526,811]	3	hSpCas9	negative selection	7141033
5314200	5314223	20	-	27260156	K562	viability	TTCGCAGCCAAGATCGTCATTGG	PROKR2	ENSG00000101292	-0.32907998658439297	[1221]	[1372,822,863,474]	-4	hSpCas9	negative selection	7205290
5314217	5314240	20	+	27260156	K562	viability	TGCGAAGAAGGTCCGGGTCTTGG	PROKR2	ENSG00000101292	0.27222828271020355	[416]	[380,547,233,603]	3	hSpCas9	negative selection	7205291
5314193	5314216	20	+	27260156	K562	viability	TGCAATGCCAATGACGATCTTGG	PROKR2	ENSG00000101292	0.48931746406519383	[1016]	[1329,1514,1576,722]	6	hSpCas9	negative selection	7205292
5314111	5314134	20	+	27260156	HT29	viability	GGTTGCGCAACTTCTTATAGCGG	PROKR2	ENSG00000101292	-0.0939673401210448	[65]	[134,74,48,48]	-2	hSpCas9	negative selection	7262282
5302686	5302709	20	+	27260156	HT29	viability	GCCGTTTGATAATTCATCCGTGG	PROKR2	ENSG00000101292	0.06912975110743036	[274]	[572,292,299,257]	1	hSpCas9	negative selection	7262283
5302232	5302255	20	+	27260156	HT29	viability	GATGCACTCGACCACGTAGAAGG	PROKR2	ENSG00000101292	0.11376168867140224	[657]	[1099,727,885,760]	2	hSpCas9	negative selection	7262284
5314200	5314223	20	-	27260156	HT29	viability	TTCGCAGCCAAGATCGTCATTGG	PROKR2	ENSG00000101292	-0.1777297472763033	[1221]	[1346,1401,1282,1231]	-4	hSpCas9	negative selection	7326541
5314217	5314240	20	+	27260156	HT29	viability	TGCGAAGAAGGTCCGGGTCTTGG	PROKR2	ENSG00000101292	0.5492518747117678	[416]	[817,808,843,528]	9	hSpCas9	negative selection	7326542
5314193	5314216	20	+	27260156	HT29	viability	TGCAATGCCAATGACGATCTTGG	PROKR2	ENSG00000101292	-0.20459755813656832	[1016]	[941,1269,1244,859]	-4	hSpCas9	negative selection	7326543
5314111	5314134	20	+	27260156	MHHES1	viability	GGTTGCGCAACTTCTTATAGCGG	PROKR2	ENSG00000101292	0.592928853738691	[65]	[174,69,116,91]	8	hSpCas9	negative selection	7383533
5302686	5302709	20	+	27260156	MHHES1	viability	GCCGTTTGATAATTCATCCGTGG	PROKR2	ENSG00000101292	0.016510597364285506	[274]	[461,278,353,193]	0	hSpCas9	negative selection	7383534
5302232	5302255	20	+	27260156	MHHES1	viability	GATGCACTCGACCACGTAGAAGG	PROKR2	ENSG00000101292	-0.1381706139729285	[657]	[747,701,701,563]	-3	hSpCas9	negative selection	7383535
5314200	5314223	20	-	27260156	MHHES1	viability	TTCGCAGCCAAGATCGTCATTGG	PROKR2	ENSG00000101292	-0.33646851870335137	[1221]	[1323,991,1158,918]	-6	hSpCas9	negative selection	7447792
5314217	5314240	20	+	27260156	MHHES1	viability	TGCGAAGAAGGTCCGGGTCTTGG	PROKR2	ENSG00000101292	-0.019489607512847867	[416]	[434,517,612,314]	0	hSpCas9	negative selection	7447793
5314193	5314216	20	+	27260156	MHHES1	viability	TGCAATGCCAATGACGATCTTGG	PROKR2	ENSG00000101292	-0.10160895601212183	[1016]	[1064,1311,934,977]	-2	hSpCas9	negative selection	7447794
5314111	5314134	20	+	27260156	MEWO	viability	GGTTGCGCAACTTCTTATAGCGG	PROKR2	ENSG00000101292	-0.01397595710495958	[65]	[73,46,64]	0	hSpCas9	negative selection	7504784
5302686	5302709	20	+	27260156	MEWO	viability	GCCGTTTGATAATTCATCCGTGG	PROKR2	ENSG00000101292	0.5463533128312987	[274]	[450,310,379]	9	hSpCas9	negative selection	7504785
5302232	5302255	20	+	27260156	MEWO	viability	GATGCACTCGACCACGTAGAAGG	PROKR2	ENSG00000101292	0.10382874124957708	[657]	[752,698,549]	2	hSpCas9	negative selection	7504786
5314200	5314223	20	-	27260156	MEWO	viability	TTCGCAGCCAAGATCGTCATTGG	PROKR2	ENSG00000101292	-0.39384702090687207	[1221]	[890,918,803]	-7	hSpCas9	negative selection	7569043
5314217	5314240	20	+	27260156	MEWO	viability	TGCGAAGAAGGTCCGGGTCTTGG	PROKR2	ENSG00000101292	0.3378082089971224	[416]	[656,457,395]	7	hSpCas9	negative selection	7569044
5314193	5314216	20	+	27260156	MEWO	viability	TGCAATGCCAATGACGATCTTGG	PROKR2	ENSG00000101292	-0.07895658023536911	[1016]	[1019,751,953]	-2	hSpCas9	negative selection	7569045
5314111	5314134	20	+	27260156	LNCAPCLONEFGC	viability	GGTTGCGCAACTTCTTATAGCGG	PROKR2	ENSG00000101292	0.02454368036334298	[65]	[88,54,73,26]	0	hSpCas9	negative selection	7626035
5302686	5302709	20	+	27260156	LNCAPCLONEFGC	viability	GCCGTTTGATAATTCATCCGTGG	PROKR2	ENSG00000101292	-0.026659725896557962	[274]	[212,269,291,208]	0	hSpCas9	negative selection	7626036
5302232	5302255	20	+	27260156	LNCAPCLONEFGC	viability	GATGCACTCGACCACGTAGAAGG	PROKR2	ENSG00000101292	-0.025071776617225316	[657]	[570,668,615,485]	0	hSpCas9	negative selection	7626037
5314200	5314223	20	-	27260156	LNCAPCLONEFGC	viability	TTCGCAGCCAAGATCGTCATTGG	PROKR2	ENSG00000101292	-0.4216609868000437	[1221]	[846,779,854,829]	-6	hSpCas9	negative selection	7690294
5314217	5314240	20	+	27260156	LNCAPCLONEFGC	viability	TGCGAAGAAGGTCCGGGTCTTGG	PROKR2	ENSG00000101292	0.4341972889720855	[416]	[526,516,594,413]	6	hSpCas9	negative selection	7690295
5314193	5314216	20	+	27260156	LNCAPCLONEFGC	viability	TGCAATGCCAATGACGATCTTGG	PROKR2	ENSG00000101292	-0.08692321387760127	[1016]	[829,743,1137,805]	-1	hSpCas9	negative selection	7690296
5314111	5314134	20	+	27260156	PANC0327	viability	GGTTGCGCAACTTCTTATAGCGG	PROKR2	ENSG00000101292	-0.8268906244997316	[65]	[17,16,27,69]	-8	hSpCas9	negative selection	7747286
5302686	5302709	20	+	27260156	PANC0327	viability	GCCGTTTGATAATTCATCCGTGG	PROKR2	ENSG00000101292	-1.3210219174151767	[274]	[81,118,78,106]	-9	hSpCas9	negative selection	7747287
5302232	5302255	20	+	27260156	PANC0327	viability	GATGCACTCGACCACGTAGAAGG	PROKR2	ENSG00000101292	0.3381361749921209	[657]	[646,545,952,826]	5	hSpCas9	negative selection	7747288
5314200	5314223	20	-	27260156	PANC0327	viability	TTCGCAGCCAAGATCGTCATTGG	PROKR2	ENSG00000101292	-0.026378536711259226	[1221]	[964,1001,1098,1196]	0	hSpCas9	negative selection	7811545
5314217	5314240	20	+	27260156	PANC0327	viability	TGCGAAGAAGGTCCGGGTCTTGG	PROKR2	ENSG00000101292	0.3507397036452269	[416]	[555,463,335,540]	5	hSpCas9	negative selection	7811546
5314193	5314216	20	+	27260156	PANC0327	viability	TGCAATGCCAATGACGATCTTGG	PROKR2	ENSG00000101292	0.41740652180082227	[1016]	[1464,861,1076,1486]	6	hSpCas9	negative selection	7811547
5314111	5314134	20	+	27260156	NCIH2009	viability	GGTTGCGCAACTTCTTATAGCGG	PROKR2	ENSG00000101292	0.9800296557630592	[65]	[203,166,178]	9	hSpCas9	negative selection	7868537
5302686	5302709	20	+	27260156	NCIH2009	viability	GCCGTTTGATAATTCATCCGTGG	PROKR2	ENSG00000101292	-0.5155908601072879	[274]	[160,242,380]	-6	hSpCas9	negative selection	7868538
5302232	5302255	20	+	27260156	NCIH2009	viability	GATGCACTCGACCACGTAGAAGG	PROKR2	ENSG00000101292	0.2967943273816189	[657]	[1348,1098,981]	4	hSpCas9	negative selection	7868539
5314200	5314223	20	-	27260156	NCIH2009	viability	TTCGCAGCCAAGATCGTCATTGG	PROKR2	ENSG00000101292	-0.17841137656920303	[1221]	[1664,1590,1296]	-2	hSpCas9	negative selection	7932796
5314217	5314240	20	+	27260156	NCIH2009	viability	TGCGAAGAAGGTCCGGGTCTTGG	PROKR2	ENSG00000101292	-0.5470664805829878	[416]	[301,367,506]	-6	hSpCas9	negative selection	7932797
5314193	5314216	20	+	27260156	NCIH2009	viability	TGCAATGCCAATGACGATCTTGG	PROKR2	ENSG00000101292	-0.3615367549287113	[1016]	[1491,1009,891]	-5	hSpCas9	negative selection	7932798
5314111	5314134	20	+	27260156	NCIH1373	viability	GGTTGCGCAACTTCTTATAGCGG	PROKR2	ENSG00000101292	0.06425714479704414	[65]	[132,93,34,13]	0	hSpCas9	negative selection	7989788
5302686	5302709	20	+	27260156	NCIH1373	viability	GCCGTTTGATAATTCATCCGTGG	PROKR2	ENSG00000101292	-0.23746113243893763	[274]	[172,128,545,48]	-2	hSpCas9	negative selection	7989789
5302232	5302255	20	+	27260156	NCIH1373	viability	GATGCACTCGACCACGTAGAAGG	PROKR2	ENSG00000101292	-0.1451494748082155	[657]	[916,325,883,158]	-1	hSpCas9	negative selection	7989790
5314200	5314223	20	-	27260156	NCIH1373	viability	TTCGCAGCCAAGATCGTCATTGG	PROKR2	ENSG00000101292	0.3328296507073203	[1221]	[1023,2715,1702,314]	3	hSpCas9	negative selection	8054047
5314217	5314240	20	+	27260156	NCIH1373	viability	TGCGAAGAAGGTCCGGGTCTTGG	PROKR2	ENSG00000101292	-0.5091322414337895	[416]	[353,426,230,76]	-5	hSpCas9	negative selection	8054048
5314193	5314216	20	+	27260156	NCIH1373	viability	TGCAATGCCAATGACGATCTTGG	PROKR2	ENSG00000101292	-0.38267852993362916	[1016]	[882,560,949,301]	-4	hSpCas9	negative selection	8054049
5314111	5314134	20	+	27260156	PATU8902	viability	GGTTGCGCAACTTCTTATAGCGG	PROKR2	ENSG00000101292	0.6946364542286596	[65]	[71,74,294,109]	7	hSpCas9	negative selection	8111039
5302686	5302709	20	+	27260156	PATU8902	viability	GCCGTTTGATAATTCATCCGTGG	PROKR2	ENSG00000101292	0.2887198092564435	[274]	[568,957,156,236]	3	hSpCas9	negative selection	8111040
5302232	5302255	20	+	27260156	PATU8902	viability	GATGCACTCGACCACGTAGAAGG	PROKR2	ENSG00000101292	0.3509187527301886	[657]	[1354,800,1063,1509]	3	hSpCas9	negative selection	8111041
5314200	5314223	20	-	27260156	PATU8902	viability	TTCGCAGCCAAGATCGTCATTGG	PROKR2	ENSG00000101292	-0.2602996993679989	[1221]	[1743,1373,1179,1433]	-3	hSpCas9	negative selection	8175298
5314217	5314240	20	+	27260156	PATU8902	viability	TGCGAAGAAGGTCCGGGTCTTGG	PROKR2	ENSG00000101292	0.6518007584887145	[416]	[716,941,1090,839]	7	hSpCas9	negative selection	8175299
5314193	5314216	20	+	27260156	PATU8902	viability	TGCAATGCCAATGACGATCTTGG	PROKR2	ENSG00000101292	0.05605015601455965	[1016]	[1458,1613,1028,1948]	0	hSpCas9	negative selection	8175300
5314111	5314134	20	+	27260156	PANC1	viability	GGTTGCGCAACTTCTTATAGCGG	PROKR2	ENSG00000101292	0.20430663400788118	[65]	[60,69,89,43]	3	hSpCas9	negative selection	8232290
5302686	5302709	20	+	27260156	PANC1	viability	GCCGTTTGATAATTCATCCGTGG	PROKR2	ENSG00000101292	0.019596548375766853	[274]	[307,269,188,197]	0	hSpCas9	negative selection	8232291
5302232	5302255	20	+	27260156	PANC1	viability	GATGCACTCGACCACGTAGAAGG	PROKR2	ENSG00000101292	0.11782645179935736	[657]	[944,525,607,377]	1	hSpCas9	negative selection	8232292
5314200	5314223	20	-	27260156	PANC1	viability	TTCGCAGCCAAGATCGTCATTGG	PROKR2	ENSG00000101292	-0.49347027063117477	[1221]	[737,972,644,671]	-6	hSpCas9	negative selection	8296549
5314217	5314240	20	+	27260156	PANC1	viability	TGCGAAGAAGGTCCGGGTCTTGG	PROKR2	ENSG00000101292	0.5141666385200239	[416]	[536,494,434,557]	8	hSpCas9	negative selection	8296550
5314193	5314216	20	+	27260156	PANC1	viability	TGCAATGCCAATGACGATCTTGG	PROKR2	ENSG00000101292	-0.024195282420213404	[1016]	[730,1091,970,704]	0	hSpCas9	negative selection	8296551
5314111	5314134	20	+	27260156	PANC0813	viability	GGTTGCGCAACTTCTTATAGCGG	PROKR2	ENSG00000101292	0.740911314507799	[65]	[180,98,151,92]	9	hSpCas9	negative selection	8353541
5302686	5302709	20	+	27260156	PANC0813	viability	GCCGTTTGATAATTCATCCGTGG	PROKR2	ENSG00000101292	0.3580580847620302	[274]	[368,314,296,655]	6	hSpCas9	negative selection	8353542
5302232	5302255	20	+	27260156	PANC0813	viability	GATGCACTCGACCACGTAGAAGG	PROKR2	ENSG00000101292	0.3137133585013091	[657]	[1236,996,890,752]	5	hSpCas9	negative selection	8353543
5314200	5314223	20	-	27260156	PANC0813	viability	TTCGCAGCCAAGATCGTCATTGG	PROKR2	ENSG00000101292	-0.07721704919740757	[1221]	[1749,1386,1194,1154]	-1	hSpCas9	negative selection	8417800
5314217	5314240	20	+	27260156	PANC0813	viability	TGCGAAGAAGGTCCGGGTCTTGG	PROKR2	ENSG00000101292	-0.6224086811515168	[416]	[266,333,337,327]	-7	hSpCas9	negative selection	8417801
5314193	5314216	20	+	27260156	PANC0813	viability	TGCAATGCCAATGACGATCTTGG	PROKR2	ENSG00000101292	0.09081679546678778	[1016]	[1068,1240,1502,1256]	1	hSpCas9	negative selection	8417802
5314111	5314134	20	+	27260156	RDES	viability	GGTTGCGCAACTTCTTATAGCGG	PROKR2	ENSG00000101292	0.1296985151568033	[65]	[85,75,71,96]	2	hSpCas9	negative selection	8474792
5302686	5302709	20	+	27260156	RDES	viability	GCCGTTTGATAATTCATCCGTGG	PROKR2	ENSG00000101292	-0.6907640427344844	[274]	[192,166,193,231]	-8	hSpCas9	negative selection	8474793
5302232	5302255	20	+	27260156	RDES	viability	GATGCACTCGACCACGTAGAAGG	PROKR2	ENSG00000101292	-0.2735512361343855	[657]	[560,532,570,878]	-5	hSpCas9	negative selection	8474794
5314200	5314223	20	-	27260156	RDES	viability	TTCGCAGCCAAGATCGTCATTGG	PROKR2	ENSG00000101292	-0.5293591462701825	[1221]	[741,851,1000,1399]	-7	hSpCas9	negative selection	8539051
5314217	5314240	20	+	27260156	RDES	viability	TGCGAAGAAGGTCCGGGTCTTGG	PROKR2	ENSG00000101292	0.6760758211321158	[416]	[569,541,964,1087]	9	hSpCas9	negative selection	8539052
5314193	5314216	20	+	27260156	RDES	viability	TGCAATGCCAATGACGATCTTGG	PROKR2	ENSG00000101292	-0.42744154646737176	[1016]	[700,869,881,1065]	-6	hSpCas9	negative selection	8539053
5314111	5314134	20	+	27260156	PC3	viability	GGTTGCGCAACTTCTTATAGCGG	PROKR2	ENSG00000101292	0.10473801692904461	[65]	[32,118,117,37]	2	hSpCas9	negative selection	8596043
5302686	5302709	20	+	27260156	PC3	viability	GCCGTTTGATAATTCATCCGTGG	PROKR2	ENSG00000101292	0.19196316469113073	[274]	[253,250,506,306]	4	hSpCas9	negative selection	8596044
5302232	5302255	20	+	27260156	PC3	viability	GATGCACTCGACCACGTAGAAGG	PROKR2	ENSG00000101292	0.11213315692904413	[657]	[539,607,1231,654]	2	hSpCas9	negative selection	8596045
5314200	5314223	20	-	27260156	PC3	viability	TTCGCAGCCAAGATCGTCATTGG	PROKR2	ENSG00000101292	-0.41094692707705105	[1221]	[571,676,1724,1090]	-7	hSpCas9	negative selection	8660302
5314217	5314240	20	+	27260156	PC3	viability	TGCGAAGAAGGTCCGGGTCTTGG	PROKR2	ENSG00000101292	0.36981116908138933	[416]	[342,624,823,491]	7	hSpCas9	negative selection	8660303
5314193	5314216	20	+	27260156	PC3	viability	TGCAATGCCAATGACGATCTTGG	PROKR2	ENSG00000101292	0.08158650029088088	[1016]	[795,744,2107,1065]	1	hSpCas9	negative selection	8660304
5314111	5314134	20	+	27260156	PATU8988T	viability	GGTTGCGCAACTTCTTATAGCGG	PROKR2	ENSG00000101292	0.32424229536707694	[65]	[109,73,56,77]	5	hSpCas9	negative selection	8717294
5302686	5302709	20	+	27260156	PATU8988T	viability	GCCGTTTGATAATTCATCCGTGG	PROKR2	ENSG00000101292	-0.4191226060394587	[274]	[191,232,139,236]	-6	hSpCas9	negative selection	8717295
5302232	5302255	20	+	27260156	PATU8988T	viability	GATGCACTCGACCACGTAGAAGG	PROKR2	ENSG00000101292	0.04158420114766315	[657]	[532,748,717,622]	0	hSpCas9	negative selection	8717296
5314200	5314223	20	-	27260156	PATU8988T	viability	TTCGCAGCCAAGATCGTCATTGG	PROKR2	ENSG00000101292	-0.22864816956261147	[1221]	[781,1018,1101,1137]	-4	hSpCas9	negative selection	8781553
5314217	5314240	20	+	27260156	PATU8988T	viability	TGCGAAGAAGGTCCGGGTCTTGG	PROKR2	ENSG00000101292	0.399673076655066	[416]	[454,348,640,673]	6	hSpCas9	negative selection	8781554
5314193	5314216	20	+	27260156	PATU8988T	viability	TGCAATGCCAATGACGATCTTGG	PROKR2	ENSG00000101292	-0.025555810113480293	[1016]	[896,931,976,1059]	0	hSpCas9	negative selection	8781555
5314111	5314134	20	+	27260156	T47D	viability	GGTTGCGCAACTTCTTATAGCGG	PROKR2	ENSG00000101292	0.2653074789126664	[65]	[96,95,72,103]	5	hSpCas9	negative selection	8838545
5302686	5302709	20	+	27260156	T47D	viability	GCCGTTTGATAATTCATCCGTGG	PROKR2	ENSG00000101292	0.15193009944473546	[274]	[314,373,327,406]	3	hSpCas9	negative selection	8838546
5302232	5302255	20	+	27260156	T47D	viability	GATGCACTCGACCACGTAGAAGG	PROKR2	ENSG00000101292	-0.16032916374544126	[657]	[720,644,655,726]	-4	hSpCas9	negative selection	8838547
5314200	5314223	20	-	27260156	T47D	viability	TTCGCAGCCAAGATCGTCATTGG	PROKR2	ENSG00000101292	-0.17673458344333426	[1221]	[1242,1342,1170,1274]	-4	hSpCas9	negative selection	8902804
5314217	5314240	20	+	27260156	T47D	viability	TGCGAAGAAGGTCCGGGTCTTGG	PROKR2	ENSG00000101292	0.4282125131123107	[416]	[681,513,690,741]	8	hSpCas9	negative selection	8902805
5314193	5314216	20	+	27260156	T47D	viability	TGCAATGCCAATGACGATCTTGG	PROKR2	ENSG00000101292	-0.04097722574871443	[1016]	[1079,974,1086,1490]	-1	hSpCas9	negative selection	8902806
5314111	5314134	20	+	27260156	SU8686	viability	GGTTGCGCAACTTCTTATAGCGG	PROKR2	ENSG00000101292	1.1321756932884646	[65]	[120,137,91,238]	9	hSpCas9	negative selection	8959796
5302686	5302709	20	+	27260156	SU8686	viability	GCCGTTTGATAATTCATCCGTGG	PROKR2	ENSG00000101292	0.1209986744192939	[274]	[240,204,387,384]	2	hSpCas9	negative selection	8959797
5302232	5302255	20	+	27260156	SU8686	viability	GATGCACTCGACCACGTAGAAGG	PROKR2	ENSG00000101292	-0.12186195328012389	[657]	[513,535,488,921]	-2	hSpCas9	negative selection	8959798
5314200	5314223	20	-	27260156	SU8686	viability	TTCGCAGCCAAGATCGTCATTGG	PROKR2	ENSG00000101292	-0.044880355076741374	[1221]	[1098,1027,1306,1307]	-1	hSpCas9	negative selection	9024055
5314217	5314240	20	+	27260156	SU8686	viability	TGCGAAGAAGGTCCGGGTCTTGG	PROKR2	ENSG00000101292	-0.5587063499489837	[416]	[273,233,247,387]	-7	hSpCas9	negative selection	9024056
5314193	5314216	20	+	27260156	SU8686	viability	TGCAATGCCAATGACGATCTTGG	PROKR2	ENSG00000101292	-0.19741015390449035	[1016]	[983,728,794,1032]	-3	hSpCas9	negative selection	9024057
5314111	5314134	20	+	27260156	SKES1	viability	GGTTGCGCAACTTCTTATAGCGG	PROKR2	ENSG00000101292	0.05394347951708456	[65]	[49,86,31,99]	1	hSpCas9	negative selection	9081047
5302686	5302709	20	+	27260156	SKES1	viability	GCCGTTTGATAATTCATCCGTGG	PROKR2	ENSG00000101292	-0.08664521731948793	[274]	[287,231,267,244]	-2	hSpCas9	negative selection	9081048
5302232	5302255	20	+	27260156	SKES1	viability	GATGCACTCGACCACGTAGAAGG	PROKR2	ENSG00000101292	-0.08725611089263102	[657]	[624,766,551,548]	-2	hSpCas9	negative selection	9081049
5314200	5314223	20	-	27260156	SKES1	viability	TTCGCAGCCAAGATCGTCATTGG	PROKR2	ENSG00000101292	-0.365556573438806	[1221]	[1219,976,813,821]	-7	hSpCas9	negative selection	9145306
5314217	5314240	20	+	27260156	SKES1	viability	TGCGAAGAAGGTCCGGGTCTTGG	PROKR2	ENSG00000101292	0.48262109804357944	[416]	[621,697,653,386]	8	hSpCas9	negative selection	9145307
5314193	5314216	20	+	27260156	SKES1	viability	TGCAATGCCAATGACGATCTTGG	PROKR2	ENSG00000101292	-0.27716817721702347	[1016]	[807,1211,652,723]	-6	hSpCas9	negative selection	9145308
5314111	5314134	20	+	27260156	TOV112D	viability	GGTTGCGCAACTTCTTATAGCGG	PROKR2	ENSG00000101292	0.44097090515828397	[65]	[186,141,2,48]	7	hSpCas9	negative selection	9202298
5302686	5302709	20	+	27260156	TOV112D	viability	GCCGTTTGATAATTCATCCGTGG	PROKR2	ENSG00000101292	-0.18268662129388025	[274]	[129,302,240,299]	-4	hSpCas9	negative selection	9202299
5302232	5302255	20	+	27260156	TOV112D	viability	GATGCACTCGACCACGTAGAAGG	PROKR2	ENSG00000101292	-0.27915579172887206	[657]	[449,651,639,450]	-5	hSpCas9	negative selection	9202300
5314200	5314223	20	-	27260156	TOV112D	viability	TTCGCAGCCAAGATCGTCATTGG	PROKR2	ENSG00000101292	-0.27653043483050777	[1221]	[1268,1177,1007,657]	-5	hSpCas9	negative selection	9266557
5314217	5314240	20	+	27260156	TOV112D	viability	TGCGAAGAAGGTCCGGGTCTTGG	PROKR2	ENSG00000101292	0.08545954862892383	[416]	[381,881,324,289]	1	hSpCas9	negative selection	9266558
5314193	5314216	20	+	27260156	TOV112D	viability	TGCAATGCCAATGACGATCTTGG	PROKR2	ENSG00000101292	0.030618443840452425	[1016]	[924,1431,1152,744]	0	hSpCas9	negative selection	9266559
5314111	5314134	20	+	27260156	TC71	viability	GGTTGCGCAACTTCTTATAGCGG	PROKR2	ENSG00000101292	0.4035609740432493	[65]	[47,104,109,112]	8	hSpCas9	negative selection	9323549
5302686	5302709	20	+	27260156	TC71	viability	GCCGTTTGATAATTCATCCGTGG	PROKR2	ENSG00000101292	-0.018447806050514992	[274]	[245,346,265,307]	0	hSpCas9	negative selection	9323550
5302232	5302255	20	+	27260156	TC71	viability	GATGCACTCGACCACGTAGAAGG	PROKR2	ENSG00000101292	-0.07962301615933587	[657]	[591,733,698,643]	-2	hSpCas9	negative selection	9323551
5314200	5314223	20	-	27260156	TC71	viability	TTCGCAGCCAAGATCGTCATTGG	PROKR2	ENSG00000101292	-0.3084867395314077	[1221]	[984,1238,952,1058]	-7	hSpCas9	negative selection	9387808
5314217	5314240	20	+	27260156	TC71	viability	TGCGAAGAAGGTCCGGGTCTTGG	PROKR2	ENSG00000101292	0.33161342905423463	[416]	[627,516,523,581]	7	hSpCas9	negative selection	9387809
5314193	5314216	20	+	27260156	TC71	viability	TGCAATGCCAATGACGATCTTGG	PROKR2	ENSG00000101292	-0.0033621883144230313	[1016]	[1183,1055,787,1345]	0	hSpCas9	negative selection	9387810
5314111	5314134	20	+	27260156	TC32	viability	GGTTGCGCAACTTCTTATAGCGG	PROKR2	ENSG00000101292	0.03286054817748063	[65]	[72,66,50,52]	0	hSpCas9	negative selection	9444800
5302686	5302709	20	+	27260156	TC32	viability	GCCGTTTGATAATTCATCCGTGG	PROKR2	ENSG00000101292	-0.4874316401472668	[274]	[163,82,296,247]	-7	hSpCas9	negative selection	9444801
5302232	5302255	20	+	27260156	TC32	viability	GATGCACTCGACCACGTAGAAGG	PROKR2	ENSG00000101292	-0.2424594389366721	[657]	[515,360,587,676]	-4	hSpCas9	negative selection	9444802
5314200	5314223	20	-	27260156	TC32	viability	TTCGCAGCCAAGATCGTCATTGG	PROKR2	ENSG00000101292	-0.332462728062326	[1221]	[913,629,1141,1062]	-6	hSpCas9	negative selection	9509059
5314217	5314240	20	+	27260156	TC32	viability	TGCGAAGAAGGTCCGGGTCTTGG	PROKR2	ENSG00000101292	0.6223869397624948	[416]	[435,654,604,683]	9	hSpCas9	negative selection	9509060
5314193	5314216	20	+	27260156	TC32	viability	TGCAATGCCAATGACGATCTTGG	PROKR2	ENSG00000101292	-0.11958894118989793	[1016]	[756,847,957,943]	-2	hSpCas9	negative selection	9509061
5302124	5302147	20	-	27869803	HPAFII	viability after 27 days	TGCACTGGCGTCCCTCCCAGCGG	PROKR2	ENSG00000101292	-0.035531516250028095	[343]	[104,235,NaN]	0	hSpCas9	negative selection	9578239
5302501	5302524	20	+	27869803	HPAFII	viability after 27 days	ACTCGACACCAAAGATGAAGAGG	PROKR2	ENSG00000101292	0.3479457704646497	[257]	[134,203,NaN]	3	hSpCas9	negative selection	9578240
5302631	5302654	20	+	27869803	HPAFII	viability after 27 days	CGATGGGATGGCAATGAGAATGG	PROKR2	ENSG00000101292	0.06946308648457156	[540]	[238,347,NaN]	0	hSpCas9	negative selection	9578241
5313949	5313972	20	+	27869803	HPAFII	viability after 27 days	CGTAGAGGGAGACGGTGCGCAGG	PROKR2	ENSG00000101292	0.2606095424963162	[305]	[231,159,NaN]	2	hSpCas9	negative selection	9578242
5314189	5314212	20	-	27869803	HPAFII	viability after 27 days	GATCGTCATTGGCATTGCACTGG	PROKR2	ENSG00000101292	0.8896126041766829	[104]	[218,4,NaN]	7	hSpCas9	negative selection	9578243
5314246	5314269	20	+	27869803	HPAFII	viability after 27 days	CCTCATCCTCATCCATAGGGAGG	PROKR2	ENSG00000101292	-0.45241669676718865	[158]	[71,51,NaN]	-3	hSpCas9	negative selection	9578244
5302124	5302147	20	-	27869803	HPAFII	viability after 15 days	TGCACTGGCGTCCCTCCCAGCGG	PROKR2	ENSG00000101292	0.6895665741076102	[343]	[734,509,NaN]	7	hSpCas9	negative selection	9660688
5302501	5302524	20	+	27869803	HPAFII	viability after 15 days	ACTCGACACCAAAGATGAAGAGG	PROKR2	ENSG00000101292	-0.1635152303504533	[257]	[270,232,NaN]	-2	hSpCas9	negative selection	9660689
5302631	5302654	20	+	27869803	HPAFII	viability after 15 days	CGATGGGATGGCAATGAGAATGG	PROKR2	ENSG00000101292	-0.09298656863613952	[540]	[747,418,NaN]	-1	hSpCas9	negative selection	9660690
5313949	5313972	20	+	27869803	HPAFII	viability after 15 days	CGTAGAGGGAGACGGTGCGCAGG	PROKR2	ENSG00000101292	0.1515493017597106	[305]	[643,191,NaN]	1	hSpCas9	negative selection	9660691
5314189	5314212	20	-	27869803	HPAFII	viability after 15 days	GATCGTCATTGGCATTGCACTGG	PROKR2	ENSG00000101292	0.6443655664690217	[104]	[369,55,NaN]	7	hSpCas9	negative selection	9660692
5314246	5314269	20	+	27869803	HPAFII	viability after 15 days	CCTCATCCTCATCCATAGGGAGG	PROKR2	ENSG00000101292	-0.5206906722907246	[158]	[62,153,NaN]	-5	hSpCas9	negative selection	9660693
5302124	5302147	20	-	27869803	ASPC1	viability after 36 days	TGCACTGGCGTCCCTCCCAGCGG	PROKR2	ENSG00000101292	0.11774599803423358	[1021]	[581,491,162]	1	hSpCas9	negative selection	9743137
5302501	5302524	20	+	27869803	ASPC1	viability after 36 days	ACTCGACACCAAAGATGAAGAGG	PROKR2	ENSG00000101292	0.16607781347343195	[642]	[45,598,117]	1	hSpCas9	negative selection	9743138
5302631	5302654	20	+	27869803	ASPC1	viability after 36 days	CGATGGGATGGCAATGAGAATGG	PROKR2	ENSG00000101292	0.10728354168645438	[1069]	[471,447,312]	1	hSpCas9	negative selection	9743139
5313949	5313972	20	+	27869803	ASPC1	viability after 36 days	CGTAGAGGGAGACGGTGCGCAGG	PROKR2	ENSG00000101292	-0.3443505436249107	[1099]	[137,335,387]	-4	hSpCas9	negative selection	9743140
5314189	5314212	20	-	27869803	ASPC1	viability after 36 days	GATCGTCATTGGCATTGCACTGG	PROKR2	ENSG00000101292	-0.15603995760958533	[336]	[63,186,68]	-2	hSpCas9	negative selection	9743141
5314246	5314269	20	+	27869803	ASPC1	viability after 36 days	CCTCATCCTCATCCATAGGGAGG	PROKR2	ENSG00000101292	0.22727872665011986	[639]	[338,188,261]	2	hSpCas9	negative selection	9743142
5302124	5302147	20	-	27869803	PATU8988S	viability after 35 days	TGCACTGGCGTCCCTCCCAGCGG	PROKR2	ENSG00000101292	-0.31268629657058655	[974]	[387,243,NaN]	-3	hSpCas9	negative selection	9825586
5302501	5302524	20	+	27869803	PATU8988S	viability after 35 days	ACTCGACACCAAAGATGAAGAGG	PROKR2	ENSG00000101292	0.3511054699325765	[470]	[225,257,NaN]	4	hSpCas9	negative selection	9825587
5302631	5302654	20	+	27869803	PATU8988S	viability after 35 days	CGATGGGATGGCAATGAGAATGG	PROKR2	ENSG00000101292	0.16457512371075134	[964]	[486,383,NaN]	2	hSpCas9	negative selection	9825588
5313949	5313972	20	+	27869803	PATU8988S	viability after 35 days	CGTAGAGGGAGACGGTGCGCAGG	PROKR2	ENSG00000101292	0.011595481759288206	[708]	[442,131,NaN]	0	hSpCas9	negative selection	9825589
5314189	5314212	20	-	27869803	PATU8988S	viability after 35 days	GATCGTCATTGGCATTGCACTGG	PROKR2	ENSG00000101292	-0.3258630203738416	[296]	[65,124,NaN]	-3	hSpCas9	negative selection	9825590
5314246	5314269	20	+	27869803	PATU8988S	viability after 35 days	CCTCATCCTCATCCATAGGGAGG	PROKR2	ENSG00000101292	-0.17672062282890133	[424]	[122,179,NaN]	-2	hSpCas9	negative selection	9825591
5302124	5302147	20	-	27869803	PATU8988S	viability after 31 days	TGCACTGGCGTCCCTCCCAGCGG	PROKR2	ENSG00000101292	0.18132426230515086	[974]	[446,432,NaN]	2	hSpCas9	negative selection	9908035
5302501	5302524	20	+	27869803	PATU8988S	viability after 31 days	ACTCGACACCAAAGATGAAGAGG	PROKR2	ENSG00000101292	0.08498733971502548	[470]	[218,173,NaN]	1	hSpCas9	negative selection	9908036
5302631	5302654	20	+	27869803	PATU8988S	viability after 31 days	CGATGGGATGGCAATGAGAATGG	PROKR2	ENSG00000101292	0.44780695055337827	[964]	[508,544,NaN]	5	hSpCas9	negative selection	9908037
5313949	5313972	20	+	27869803	PATU8988S	viability after 31 days	CGTAGAGGGAGACGGTGCGCAGG	PROKR2	ENSG00000101292	0.0982816511788207	[708]	[299,305,NaN]	1	hSpCas9	negative selection	9908038
5314189	5314212	20	-	27869803	PATU8988S	viability after 31 days	GATCGTCATTGGCATTGCACTGG	PROKR2	ENSG00000101292	-0.5775843621568731	[296]	[59,103,NaN]	-6	hSpCas9	negative selection	9908039
5314246	5314269	20	+	27869803	PATU8988S	viability after 31 days	CCTCATCCTCATCCATAGGGAGG	PROKR2	ENSG00000101292	0.13149010091237986	[424]	[171,202,NaN]	1	hSpCas9	negative selection	9908040
5302124	5302147	20	-	27869803	HPAFII	viability after 35 days	TGCACTGGCGTCCCTCCCAGCGG	PROKR2	ENSG00000101292	-0.40467191859788804	[343]	[60,210,NaN]	-2	hSpCas9	negative selection	9990484
5302501	5302524	20	+	27869803	HPAFII	viability after 35 days	ACTCGACACCAAAGATGAAGAGG	PROKR2	ENSG00000101292	0.2644647078895122	[257]	[51,274,NaN]	1	hSpCas9	negative selection	9990485
5302631	5302654	20	+	27869803	HPAFII	viability after 35 days	CGATGGGATGGCAATGAGAATGG	PROKR2	ENSG00000101292	0.4737493329168625	[540]	[353,409,NaN]	3	hSpCas9	negative selection	9990486
5313949	5313972	20	+	27869803	HPAFII	viability after 35 days	CGTAGAGGGAGACGGTGCGCAGG	PROKR2	ENSG00000101292	0.21462004751373243	[305]	[167,192,NaN]	1	hSpCas9	negative selection	9990487
5314189	5314212	20	-	27869803	HPAFII	viability after 35 days	GATCGTCATTGGCATTGCACTGG	PROKR2	ENSG00000101292	1.1176406025094818	[104]	[215,1,NaN]	7	hSpCas9	negative selection	9990488
5314246	5314269	20	+	27869803	HPAFII	viability after 35 days	CCTCATCCTCATCCATAGGGAGG	PROKR2	ENSG00000101292	-0.3414363665413501	[158]	[63,62,NaN]	-2	hSpCas9	negative selection	9990489
5302124	5302147	20	-	27869803	HPAFII	viability after 31 days	TGCACTGGCGTCCCTCCCAGCGG	PROKR2	ENSG00000101292	-0.18957713329882303	[343]	[63,283,NaN]	-1	hSpCas9	negative selection	10072933
5302501	5302524	20	+	27869803	HPAFII	viability after 31 days	ACTCGACACCAAAGATGAAGAGG	PROKR2	ENSG00000101292	0.03006467702159043	[257]	[54,248,NaN]	0	hSpCas9	negative selection	10072934
5302631	5302654	20	+	27869803	HPAFII	viability after 31 days	CGATGGGATGGCAATGAGAATGG	PROKR2	ENSG00000101292	0.40370713848776774	[540]	[326,482,NaN]	3	hSpCas9	negative selection	10072935
5313949	5313972	20	+	27869803	HPAFII	viability after 31 days	CGTAGAGGGAGACGGTGCGCAGG	PROKR2	ENSG00000101292	-0.5788850701568333	[305]	[91,139,NaN]	-4	hSpCas9	negative selection	10072936
5314189	5314212	20	-	27869803	HPAFII	viability after 31 days	GATCGTCATTGGCATTGCACTGG	PROKR2	ENSG00000101292	1.504248523469521	[104]	[315,4,NaN]	9	hSpCas9	negative selection	10072937
5314246	5314269	20	+	27869803	HPAFII	viability after 31 days	CCTCATCCTCATCCATAGGGAGG	PROKR2	ENSG00000101292	0.06219334675888977	[158]	[107,76,NaN]	0	hSpCas9	negative selection	10072938
5313962	5313985	20	+	28162770	P31FUJ	viability	GGTGCGCAGGTAGTTGACGGAGG	PROKR2	ENSG00000101292	0.2468072961605488	[141]	[197]	2	hSpCas9	negative selection	10217489
5314189	5314212	20	-	28162770	P31FUJ	viability	GATCGTCATTGGCATTGCACTGG	PROKR2	ENSG00000101292	0.5821329593735562	[460]	[810]	6	hSpCas9	negative selection	10217490
5314302	5314325	20	+	28162770	P31FUJ	viability	GAGGAGGCATGGTCTTGGGGTGG	PROKR2	ENSG00000101292	-0.17006644906641588	[44]	[46]	-2	hSpCas9	negative selection	10217491
5314286	5314309	20	+	28162770	P31FUJ	viability	GAAGTTAAAGGAGAGGGAGGAGG	PROKR2	ENSG00000101292	-1.6421931405520804	[84]	[31]	-8	hSpCas9	negative selection	10217492
5313941	5313964	20	+	28162770	P31FUJ	viability	GGTGGAGACGTAGAGGGAGACGG	PROKR2	ENSG00000101292	-5.947047722080502	[104]	[1]	-9	hSpCas9	negative selection	10217493
5314061	5314084	20	+	28162770	P31FUJ	viability	GGCCACCAGGAAGTCGGAGATGG	PROKR2	ENSG00000101292	0.4663900471199024	[177]	[288]	5	hSpCas9	negative selection	10217494
5314246	5314269	20	+	28162770	P31FUJ	viability	CCTCATCCTCATCCATAGGGAGG	PROKR2	ENSG00000101292	0.6557225087231818	[194]	[360]	7	hSpCas9	negative selection	10217495
5314036	5314059	20	-	28162770	P31FUJ	viability	CATCTGCTGCCCCTTCGAGATGG	PROKR2	ENSG00000101292	0.46215292255248763	[222]	[360]	5	hSpCas9	negative selection	10217496
5313920	5313943	20	+	28162770	P31FUJ	viability	GGCAATGGCCAGCAAGGCATTGG	PROKR2	ENSG00000101292	0.16998014295782315	[797]	[1054]	1	hSpCas9	negative selection	10217497
5314229	5314252	20	-	28162770	P31FUJ	viability	ATGAGGACATGACCAAGACCCGG	PROKR2	ENSG00000101292	0.19133750197171784	[394]	[529]	2	hSpCas9	negative selection	10217498
5313962	5313985	20	+	28162770	TF1	viability	GGTGCGCAGGTAGTTGACGGAGG	PROKR2	ENSG00000101292	NaN	[NaN]	[132]	1	hSpCas9	negative selection	10386855
5314189	5314212	20	-	28162770	TF1	viability	GATCGTCATTGGCATTGCACTGG	PROKR2	ENSG00000101292	NaN	[NaN]	[572]	1	hSpCas9	negative selection	10386856
5314302	5314325	20	+	28162770	TF1	viability	GAGGAGGCATGGTCTTGGGGTGG	PROKR2	ENSG00000101292	NaN	[NaN]	[9]	1	hSpCas9	negative selection	10386857
5314286	5314309	20	+	28162770	TF1	viability	GAAGTTAAAGGAGAGGGAGGAGG	PROKR2	ENSG00000101292	NaN	[NaN]	[0]	1	hSpCas9	negative selection	10386858
5313941	5313964	20	+	28162770	TF1	viability	GGTGGAGACGTAGAGGGAGACGG	PROKR2	ENSG00000101292	NaN	[NaN]	[0]	1	hSpCas9	negative selection	10386859
5314061	5314084	20	+	28162770	TF1	viability	GGCCACCAGGAAGTCGGAGATGG	PROKR2	ENSG00000101292	NaN	[NaN]	[149]	1	hSpCas9	negative selection	10386860
5314246	5314269	20	+	28162770	TF1	viability	CCTCATCCTCATCCATAGGGAGG	PROKR2	ENSG00000101292	NaN	[NaN]	[274]	1	hSpCas9	negative selection	10386861
5314036	5314059	20	-	28162770	TF1	viability	CATCTGCTGCCCCTTCGAGATGG	PROKR2	ENSG00000101292	NaN	[NaN]	[233]	1	hSpCas9	negative selection	10386862
5313920	5313943	20	+	28162770	TF1	viability	GGCAATGGCCAGCAAGGCATTGG	PROKR2	ENSG00000101292	NaN	[NaN]	[547]	1	hSpCas9	negative selection	10386863
5314229	5314252	20	-	28162770	TF1	viability	ATGAGGACATGACCAAGACCCGG	PROKR2	ENSG00000101292	NaN	[NaN]	[350]	1	hSpCas9	negative selection	10386864
5313962	5313985	20	+	28162770	SKM1	viability	GGTGCGCAGGTAGTTGACGGAGG	PROKR2	ENSG00000101292	0.49210689240605765	[36]	[91]	5	hSpCas9	negative selection	10556221
5314189	5314212	20	-	28162770	SKM1	viability	GATCGTCATTGGCATTGCACTGG	PROKR2	ENSG00000101292	0.41503749927884404	[97]	[230]	4	hSpCas9	negative selection	10556222
5314302	5314325	20	+	28162770	SKM1	viability	GAGGAGGCATGGTCTTGGGGTGG	PROKR2	ENSG00000101292	-0.7548875021634687	[20]	[21]	-5	hSpCas9	negative selection	10556223
5314286	5314309	20	+	28162770	SKM1	viability	GAAGTTAAAGGAGAGGGAGGAGG	PROKR2	ENSG00000101292	0.10399772053421752	[19]	[37]	1	hSpCas9	negative selection	10556224
5313941	5313964	20	+	28162770	SKM1	viability	GGTGGAGACGTAGAGGGAGACGG	PROKR2	ENSG00000101292	-2.8220016980220053	[23]	[5]	-9	hSpCas9	negative selection	10556225
5314061	5314084	20	+	28162770	SKM1	viability	GGCCACCAGGAAGTCGGAGATGG	PROKR2	ENSG00000101292	0.8267367131324653	[58]	[184]	7	hSpCas9	negative selection	10556226
5314246	5314269	20	+	28162770	SKM1	viability	CCTCATCCTCATCCATAGGGAGG	PROKR2	ENSG00000101292	-0.7492453555866916	[57]	[60]	-5	hSpCas9	negative selection	10556227
5314036	5314059	20	-	28162770	SKM1	viability	CATCTGCTGCCCCTTCGAGATGG	PROKR2	ENSG00000101292	0.194300114307095	[43]	[88]	2	hSpCas9	negative selection	10556228
5313920	5313943	20	+	28162770	SKM1	viability	GGCAATGGCCAGCAAGGCATTGG	PROKR2	ENSG00000101292	0.0874310921489665	[188]	[354]	0	hSpCas9	negative selection	10556229
5314229	5314252	20	-	28162770	SKM1	viability	ATGAGGACATGACCAAGACCCGG	PROKR2	ENSG00000101292	0.5284955490621277	[59]	[152]	5	hSpCas9	negative selection	10556230
5313962	5313985	20	+	28162770	SKM1	viability	GGTGCGCAGGTAGTTGACGGAGG	PROKR2	ENSG00000101292	0.49210689240605765	[36]	[91]	5	hSpCas9	negative selection	10725587
5314189	5314212	20	-	28162770	SKM1	viability	GATCGTCATTGGCATTGCACTGG	PROKR2	ENSG00000101292	0.41503749927884404	[97]	[230]	4	hSpCas9	negative selection	10725588
5314302	5314325	20	+	28162770	SKM1	viability	GAGGAGGCATGGTCTTGGGGTGG	PROKR2	ENSG00000101292	-0.7548875021634687	[20]	[21]	-5	hSpCas9	negative selection	10725589
5314286	5314309	20	+	28162770	SKM1	viability	GAAGTTAAAGGAGAGGGAGGAGG	PROKR2	ENSG00000101292	0.10399772053421752	[19]	[37]	1	hSpCas9	negative selection	10725590
5313941	5313964	20	+	28162770	SKM1	viability	GGTGGAGACGTAGAGGGAGACGG	PROKR2	ENSG00000101292	-2.8220016980220053	[23]	[5]	-9	hSpCas9	negative selection	10725591
5314061	5314084	20	+	28162770	SKM1	viability	GGCCACCAGGAAGTCGGAGATGG	PROKR2	ENSG00000101292	0.8267367131324653	[58]	[184]	7	hSpCas9	negative selection	10725592
5314246	5314269	20	+	28162770	SKM1	viability	CCTCATCCTCATCCATAGGGAGG	PROKR2	ENSG00000101292	-0.7492453555866916	[57]	[60]	-5	hSpCas9	negative selection	10725593
5314036	5314059	20	-	28162770	SKM1	viability	CATCTGCTGCCCCTTCGAGATGG	PROKR2	ENSG00000101292	0.194300114307095	[43]	[88]	2	hSpCas9	negative selection	10725594
5313920	5313943	20	+	28162770	SKM1	viability	GGCAATGGCCAGCAAGGCATTGG	PROKR2	ENSG00000101292	0.0874310921489665	[188]	[354]	0	hSpCas9	negative selection	10725595
5314229	5314252	20	-	28162770	SKM1	viability	ATGAGGACATGACCAAGACCCGG	PROKR2	ENSG00000101292	0.5284955490621277	[59]	[152]	5	hSpCas9	negative selection	10725596
5313962	5313985	20	+	28162770	PL21	viability	GGTGCGCAGGTAGTTGACGGAGG	PROKR2	ENSG00000101292	0.9591315149855253	[155]	[131]	7	hSpCas9	negative selection	10894953
5314189	5314212	20	-	28162770	PL21	viability	GATCGTCATTGGCATTGCACTGG	PROKR2	ENSG00000101292	0.0749844831670301	[348]	[159]	0	hSpCas9	negative selection	10894954
5314302	5314325	20	+	28162770	PL21	viability	GAGGAGGCATGGTCTTGGGGTGG	PROKR2	ENSG00000101292	-1.819759942948385	[72]	[8]	-8	hSpCas9	negative selection	10894955
5314286	5314309	20	+	28162770	PL21	viability	GAAGTTAAAGGAGAGGGAGGAGG	PROKR2	ENSG00000101292	0.03455354877134509	[82]	[36]	0	hSpCas9	negative selection	10894956
5313941	5313964	20	+	28162770	PL21	viability	GGTGGAGACGTAGAGGGAGACGG	PROKR2	ENSG00000101292	-2.246116615400244	[108]	[9]	-8	hSpCas9	negative selection	10894957
5314061	5314084	20	+	28162770	PL21	viability	GGCCACCAGGAAGTCGGAGATGG	PROKR2	ENSG00000101292	0.4696002894825472	[223]	[134]	4	hSpCas9	negative selection	10894958
5314246	5314269	20	+	28162770	PL21	viability	CCTCATCCTCATCCATAGGGAGG	PROKR2	ENSG00000101292	0.6748200601955657	[153]	[106]	6	hSpCas9	negative selection	10894959
5314036	5314059	20	-	28162770	PL21	viability	CATCTGCTGCCCCTTCGAGATGG	PROKR2	ENSG00000101292	-0.2917134818403547	[134]	[47]	-2	hSpCas9	negative selection	10894960
5313920	5313943	20	+	28162770	PL21	viability	GGCAATGGCCAGCAAGGCATTGG	PROKR2	ENSG00000101292	-0.30948956100654734	[540]	[189]	-2	hSpCas9	negative selection	10894961
5314229	5314252	20	-	28162770	PL21	viability	ATGAGGACATGACCAAGACCCGG	PROKR2	ENSG00000101292	0.30858634194763046	[268]	[144]	2	hSpCas9	negative selection	10894962
5313962	5313985	20	+	28162770	P31FUJ	viability	GGTGCGCAGGTAGTTGACGGAGG	PROKR2	ENSG00000101292	0.2468072961605488	[141]	[197]	2	hSpCas9	negative selection	11064319
5314189	5314212	20	-	28162770	P31FUJ	viability	GATCGTCATTGGCATTGCACTGG	PROKR2	ENSG00000101292	0.5821329593735562	[460]	[810]	6	hSpCas9	negative selection	11064320
5314302	5314325	20	+	28162770	P31FUJ	viability	GAGGAGGCATGGTCTTGGGGTGG	PROKR2	ENSG00000101292	-0.17006644906641588	[44]	[46]	-2	hSpCas9	negative selection	11064321
5314286	5314309	20	+	28162770	P31FUJ	viability	GAAGTTAAAGGAGAGGGAGGAGG	PROKR2	ENSG00000101292	-1.6421931405520804	[84]	[31]	-8	hSpCas9	negative selection	11064322
5313941	5313964	20	+	28162770	P31FUJ	viability	GGTGGAGACGTAGAGGGAGACGG	PROKR2	ENSG00000101292	-5.947047722080502	[104]	[1]	-9	hSpCas9	negative selection	11064323
5314061	5314084	20	+	28162770	P31FUJ	viability	GGCCACCAGGAAGTCGGAGATGG	PROKR2	ENSG00000101292	0.4663900471199024	[177]	[288]	5	hSpCas9	negative selection	11064324
5314246	5314269	20	+	28162770	P31FUJ	viability	CCTCATCCTCATCCATAGGGAGG	PROKR2	ENSG00000101292	0.6557225087231818	[194]	[360]	7	hSpCas9	negative selection	11064325
5314036	5314059	20	-	28162770	P31FUJ	viability	CATCTGCTGCCCCTTCGAGATGG	PROKR2	ENSG00000101292	0.46215292255248763	[222]	[360]	5	hSpCas9	negative selection	11064326
5313920	5313943	20	+	28162770	P31FUJ	viability	GGCAATGGCCAGCAAGGCATTGG	PROKR2	ENSG00000101292	0.16998014295782315	[797]	[1054]	1	hSpCas9	negative selection	11064327
5314229	5314252	20	-	28162770	P31FUJ	viability	ATGAGGACATGACCAAGACCCGG	PROKR2	ENSG00000101292	0.19133750197171784	[394]	[529]	2	hSpCas9	negative selection	11064328
5313962	5313985	20	+	28162770	OCIAML5	viability	GGTGCGCAGGTAGTTGACGGAGG	PROKR2	ENSG00000101292	0.3655248642086299	[85]	[199]	3	hSpCas9	negative selection	11233685
5314189	5314212	20	-	28162770	OCIAML5	viability	GATCGTCATTGGCATTGCACTGG	PROKR2	ENSG00000101292	0.18477019731637423	[231]	[475]	1	hSpCas9	negative selection	11233686
5314302	5314325	20	+	28162770	OCIAML5	viability	GAGGAGGCATGGTCTTGGGGTGG	PROKR2	ENSG00000101292	-2.0959921537500863	[44]	[18]	-8	hSpCas9	negative selection	11233687
5314286	5314309	20	+	28162770	OCIAML5	viability	GAAGTTAAAGGAGAGGGAGGAGG	PROKR2	ENSG00000101292	-1.7188000400005328	[30]	[16]	-7	hSpCas9	negative selection	11233688
5313941	5313964	20	+	28162770	OCIAML5	viability	GGTGGAGACGTAGAGGGAGACGG	PROKR2	ENSG00000101292	-1.9964564801991718	[83]	[37]	-8	hSpCas9	negative selection	11233689
5314061	5314084	20	+	28162770	OCIAML5	viability	GGCCACCAGGAAGTCGGAGATGG	PROKR2	ENSG00000101292	0.5299361491710549	[126]	[330]	4	hSpCas9	negative selection	11233690
5314246	5314269	20	+	28162770	OCIAML5	viability	CCTCATCCTCATCCATAGGGAGG	PROKR2	ENSG00000101292	0.5711448598605471	[109]	[294]	5	hSpCas9	negative selection	11233691
5314036	5314059	20	-	28162770	OCIAML5	viability	CATCTGCTGCCCCTTCGAGATGG	PROKR2	ENSG00000101292	0.6027286376525814	[169]	[465]	5	hSpCas9	negative selection	11233692
5313920	5313943	20	+	28162770	OCIAML5	viability	GGCAATGGCCAGCAAGGCATTGG	PROKR2	ENSG00000101292	0.07267202607744627	[481]	[914]	0	hSpCas9	negative selection	11233693
5314229	5314252	20	-	28162770	OCIAML5	viability	ATGAGGACATGACCAAGACCCGG	PROKR2	ENSG00000101292	0.018946988415925015	[227]	[416]	0	hSpCas9	negative selection	11233694
5313962	5313985	20	+	28162770	EOL1	viability	GGTGCGCAGGTAGTTGACGGAGG	PROKR2	ENSG00000101292	0.6627728115093394	[228]	[190]	6	hSpCas9	negative selection	11403051
5314189	5314212	20	-	28162770	EOL1	viability	GATCGTCATTGGCATTGCACTGG	PROKR2	ENSG00000101292	-0.35776846741797114	[466]	[191]	-3	hSpCas9	negative selection	11403052
5314302	5314325	20	+	28162770	EOL1	viability	GAGGAGGCATGGTCTTGGGGTGG	PROKR2	ENSG00000101292	-0.903271253046785	[141]	[39]	-6	hSpCas9	negative selection	11403053
5314286	5314309	20	+	28162770	EOL1	viability	GAAGTTAAAGGAGAGGGAGGAGG	PROKR2	ENSG00000101292	0.015695659628729874	[183]	[97]	0	hSpCas9	negative selection	11403054
5313941	5313964	20	+	28162770	EOL1	viability	GGTGGAGACGTAGAGGGAGACGG	PROKR2	ENSG00000101292	-4.09782004145792	[194]	[5]	-9	hSpCas9	negative selection	11403055
5314061	5314084	20	+	28162770	EOL1	viability	GGCCACCAGGAAGTCGGAGATGG	PROKR2	ENSG00000101292	0.4054732065058354	[320]	[223]	3	hSpCas9	negative selection	11403056
5314246	5314269	20	+	28162770	EOL1	viability	CCTCATCCTCATCCATAGGGAGG	PROKR2	ENSG00000101292	0.3493004256825901	[221]	[148]	3	hSpCas9	negative selection	11403057
5314036	5314059	20	-	28162770	EOL1	viability	CATCTGCTGCCCCTTCGAGATGG	PROKR2	ENSG00000101292	0.1085106064131296	[249]	[141]	1	hSpCas9	negative selection	11403058
5313920	5313943	20	+	28162770	EOL1	viability	GGCAATGGCCAGCAAGGCATTGG	PROKR2	ENSG00000101292	-0.23950066353510846	[734]	[327]	-2	hSpCas9	negative selection	11403059
5314229	5314252	20	-	28162770	EOL1	viability	ATGAGGACATGACCAAGACCCGG	PROKR2	ENSG00000101292	-0.6604147291506216	[377]	[125]	-5	hSpCas9	negative selection	11403060
5313962	5313985	20	+	28162770	MOLM13	viability	GGTGCGCAGGTAGTTGACGGAGG	PROKR2	ENSG00000101292	0.030080574607076804	[148]	[109]	0	hSpCas9	negative selection	11572417
5314189	5314212	20	-	28162770	MOLM13	viability	GATCGTCATTGGCATTGCACTGG	PROKR2	ENSG00000101292	0.441417170183388	[549]	[539]	3	hSpCas9	negative selection	11572418
5314302	5314325	20	+	28162770	MOLM13	viability	GAGGAGGCATGGTCTTGGGGTGG	PROKR2	ENSG00000101292	-5.402475338038826	[116]	[1]	-9	hSpCas9	negative selection	11572419
5314286	5314309	20	+	28162770	MOLM13	viability	GAAGTTAAAGGAGAGGGAGGAGG	PROKR2	ENSG00000101292	-2.8643070487966105	[140]	[13]	-8	hSpCas9	negative selection	11572420
5313941	5313964	20	+	28162770	MOLM13	viability	GGTGGAGACGTAGAGGGAGACGG	PROKR2	ENSG00000101292	-1.0499589233180404	[125]	[43]	-5	hSpCas9	negative selection	11572421
5314061	5314084	20	+	28162770	MOLM13	viability	GGCCACCAGGAAGTCGGAGATGG	PROKR2	ENSG00000101292	0.134548321384115	[348]	[276]	0	hSpCas9	negative selection	11572422
5314246	5314269	20	+	28162770	MOLM13	viability	CCTCATCCTCATCCATAGGGAGG	PROKR2	ENSG00000101292	-0.17387947479505028	[258]	[165]	-1	hSpCas9	negative selection	11572423
5314036	5314059	20	-	28162770	MOLM13	viability	CATCTGCTGCCCCTTCGAGATGG	PROKR2	ENSG00000101292	0.28671962293464404	[321]	[283]	2	hSpCas9	negative selection	11572424
5313920	5313943	20	+	28162770	MOLM13	viability	GGCAATGGCCAGCAAGGCATTGG	PROKR2	ENSG00000101292	-0.553005842766771	[764]	[376]	-3	hSpCas9	negative selection	11572425
5314229	5314252	20	-	28162770	MOLM13	viability	ATGAGGACATGACCAAGACCCGG	PROKR2	ENSG00000101292	-1.1017251548431415	[373]	[125]	-5	hSpCas9	negative selection	11572426
5313962	5313985	20	+	28162770	HEL	viability	GGTGCGCAGGTAGTTGACGGAGG	PROKR2	ENSG00000101292	0.12916096451596604	[206]	[144]	1	hSpCas9	negative selection	11741783
5314189	5314212	20	-	28162770	HEL	viability	GATCGTCATTGGCATTGCACTGG	PROKR2	ENSG00000101292	-0.1935147414864551	[415]	[232]	-1	hSpCas9	negative selection	11741784
5314302	5314325	20	+	28162770	HEL	viability	GAGGAGGCATGGTCTTGGGGTGG	PROKR2	ENSG00000101292	-2.257725494448729	[111]	[14]	-8	hSpCas9	negative selection	11741785
5314286	5314309	20	+	28162770	HEL	viability	GAAGTTAAAGGAGAGGGAGGAGG	PROKR2	ENSG00000101292	0.01595615558457375	[104]	[67]	0	hSpCas9	negative selection	11741786
5313941	5313964	20	+	28162770	HEL	viability	GGTGGAGACGTAGAGGGAGACGG	PROKR2	ENSG00000101292	-3.1873361665573308	[127]	[8]	-9	hSpCas9	negative selection	11741787
5314061	5314084	20	+	28162770	HEL	viability	GGCCACCAGGAAGTCGGAGATGG	PROKR2	ENSG00000101292	0.8668196034895747	[243]	[284]	7	hSpCas9	negative selection	11741788
5314246	5314269	20	+	28162770	HEL	viability	CCTCATCCTCATCCATAGGGAGG	PROKR2	ENSG00000101292	-1.2114103015361881	[187]	[51]	-6	hSpCas9	negative selection	11741789
5314036	5314059	20	-	28162770	HEL	viability	CATCTGCTGCCCCTTCGAGATGG	PROKR2	ENSG00000101292	0.34359413275728223	[266]	[216]	3	hSpCas9	negative selection	11741790
5313920	5313943	20	+	28162770	HEL	viability	GGCAATGGCCAGCAAGGCATTGG	PROKR2	ENSG00000101292	0.21667992663026103	[656]	[488]	1	hSpCas9	negative selection	11741791
5314229	5314252	20	-	28162770	HEL	viability	ATGAGGACATGACCAAGACCCGG	PROKR2	ENSG00000101292	0.27868526144031813	[277]	[215]	2	hSpCas9	negative selection	11741792
5313962	5313985	20	+	28162770	MV411	viability	GGTGCGCAGGTAGTTGACGGAGG	PROKR2	ENSG00000101292	0.3390680262483437	[121]	[129]	3	hSpCas9	negative selection	11911149
5314189	5314212	20	-	28162770	MV411	viability	GATCGTCATTGGCATTGCACTGG	PROKR2	ENSG00000101292	0.6023347763148217	[397]	[508]	5	hSpCas9	negative selection	11911150
5314302	5314325	20	+	28162770	MV411	viability	GAGGAGGCATGGTCTTGGGGTGG	PROKR2	ENSG00000101292	-1.9541963103868754	[68]	[14]	-8	hSpCas9	negative selection	11911151
5314286	5314309	20	+	28162770	MV411	viability	GAAGTTAAAGGAGAGGGAGGAGG	PROKR2	ENSG00000101292	-0.5212369031107691	[91]	[53]	-4	hSpCas9	negative selection	11911152
5313941	5313964	20	+	28162770	MV411	viability	GGTGGAGACGTAGAGGGAGACGG	PROKR2	ENSG00000101292	-6.453002167358317	[103]	[0]	-9	hSpCas9	negative selection	11911153
5314061	5314084	20	+	28162770	MV411	viability	GGCCACCAGGAAGTCGGAGATGG	PROKR2	ENSG00000101292	1.048777057422608	[205]	[358]	8	hSpCas9	negative selection	11911154
5314246	5314269	20	+	28162770	MV411	viability	CCTCATCCTCATCCATAGGGAGG	PROKR2	ENSG00000101292	0.14332914744203668	[157]	[146]	1	hSpCas9	negative selection	11911155
5314036	5314059	20	-	28162770	MV411	viability	CATCTGCTGCCCCTTCGAGATGG	PROKR2	ENSG00000101292	1.0612187419998125	[127]	[224]	8	hSpCas9	negative selection	11911156
5313920	5313943	20	+	28162770	MV411	viability	GGCAATGGCCAGCAAGGCATTGG	PROKR2	ENSG00000101292	0.07270470614475322	[525]	[465]	0	hSpCas9	negative selection	11911157
5314229	5314252	20	-	28162770	MV411	viability	ATGAGGACATGACCAAGACCCGG	PROKR2	ENSG00000101292	0.44674635900618187	[269]	[309]	4	hSpCas9	negative selection	11911158
5313962	5313985	20	+	28162770	MONOMAC1	viability	GGTGCGCAGGTAGTTGACGGAGG	PROKR2	ENSG00000101292	1.194600219639213	[100]	[264]	9	hSpCas9	negative selection	12080515
5314189	5314212	20	-	28162770	MONOMAC1	viability	GATCGTCATTGGCATTGCACTGG	PROKR2	ENSG00000101292	1.6342561296548055	[221]	[789]	9	hSpCas9	negative selection	12080516
5314302	5314325	20	+	28162770	MONOMAC1	viability	GAGGAGGCATGGTCTTGGGGTGG	PROKR2	ENSG00000101292	-1.151233157446429	[61]	[31]	-7	hSpCas9	negative selection	12080517
5314286	5314309	20	+	28162770	MONOMAC1	viability	GAAGTTAAAGGAGAGGGAGGAGG	PROKR2	ENSG00000101292	-1.625880145863428	[69]	[25]	-8	hSpCas9	negative selection	12080518
5313941	5313964	20	+	28162770	MONOMAC1	viability	GGTGGAGACGTAGAGGGAGACGG	PROKR2	ENSG00000101292	-3.197036847059554	[47]	[5]	-9	hSpCas9	negative selection	12080519
5314061	5314084	20	+	28162770	MONOMAC1	viability	GGCCACCAGGAAGTCGGAGATGG	PROKR2	ENSG00000101292	1.311017667955821	[121]	[346]	9	hSpCas9	negative selection	12080520
5314246	5314269	20	+	28162770	MONOMAC1	viability	CCTCATCCTCATCCATAGGGAGG	PROKR2	ENSG00000101292	0.8548020844600644	[81]	[169]	7	hSpCas9	negative selection	12080521
5314036	5314059	20	-	28162770	MONOMAC1	viability	CATCTGCTGCCCCTTCGAGATGG	PROKR2	ENSG00000101292	0.3307007849686526	[119]	[172]	3	hSpCas9	negative selection	12080522
5313920	5313943	20	+	28162770	MONOMAC1	viability	GGCAATGGCCAGCAAGGCATTGG	PROKR2	ENSG00000101292	0.020158370212013832	[436]	[507]	0	hSpCas9	negative selection	12080523
5314229	5314252	20	-	28162770	MONOMAC1	viability	ATGAGGACATGACCAAGACCCGG	PROKR2	ENSG00000101292	-0.43483396139432445	[203]	[172]	-4	hSpCas9	negative selection	12080524
5313962	5313985	20	+	28162770	OCIAML2	viability	GGTGCGCAGGTAGTTGACGGAGG	PROKR2	ENSG00000101292	0.9533964572639375	[14]	[160]	8	hSpCas9	negative selection	12249881
5314189	5314212	20	-	28162770	OCIAML2	viability	GATCGTCATTGGCATTGCACTGG	PROKR2	ENSG00000101292	0.09357411531219761	[69]	[413]	0	hSpCas9	negative selection	12249882
5314302	5314325	20	+	28162770	OCIAML2	viability	GAGGAGGCATGGTCTTGGGGTGG	PROKR2	ENSG00000101292	-2.470629825242161	[19]	[19]	-8	hSpCas9	negative selection	12249883
5314286	5314309	20	+	28162770	OCIAML2	viability	GAAGTTAAAGGAGAGGGAGGAGG	PROKR2	ENSG00000101292	-1.3551526078222254	[11]	[25]	-7	hSpCas9	negative selection	12249884
5313941	5313964	20	+	28162770	OCIAML2	viability	GGTGGAGACGTAGAGGGAGACGG	PROKR2	ENSG00000101292	-2.857652948351409	[16]	[12]	-9	hSpCas9	negative selection	12249885
5314061	5314084	20	+	28162770	OCIAML2	viability	GGCCACCAGGAAGTCGGAGATGG	PROKR2	ENSG00000101292	-0.655369705099211	[51]	[182]	-5	hSpCas9	negative selection	12249886
5314246	5314269	20	+	28162770	OCIAML2	viability	CCTCATCCTCATCCATAGGGAGG	PROKR2	ENSG00000101292	-0.4573330026287034	[26]	[108]	-4	hSpCas9	negative selection	12249887
5314036	5314059	20	-	28162770	OCIAML2	viability	CATCTGCTGCCCCTTCGAGATGG	PROKR2	ENSG00000101292	0.5882638638114073	[38]	[324]	6	hSpCas9	negative selection	12249888
5313920	5313943	20	+	28162770	OCIAML2	viability	GGCAATGGCCAGCAAGGCATTGG	PROKR2	ENSG00000101292	1.027349373884355	[93]	[1061]	8	hSpCas9	negative selection	12249889
5314229	5314252	20	-	28162770	OCIAML2	viability	ATGAGGACATGACCAAGACCCGG	PROKR2	ENSG00000101292	0.47473491818099306	[36]	[284]	4	hSpCas9	negative selection	12249890
5313962	5313985	20	+	28162770	OCIAML3	viability	GGTGCGCAGGTAGTTGACGGAGG	PROKR2	ENSG00000101292	0.09135675735483073	[36]	[118]	0	hSpCas9	negative selection	12419247
5314189	5314212	20	-	28162770	OCIAML3	viability	GATCGTCATTGGCATTGCACTGG	PROKR2	ENSG00000101292	0.7522703159789479	[93]	[477]	6	hSpCas9	negative selection	12419248
5314302	5314325	20	+	28162770	OCIAML3	viability	GAGGAGGCATGGTCTTGGGGTGG	PROKR2	ENSG00000101292	-1.009045139603007	[13]	[20]	-6	hSpCas9	negative selection	12419249
5314286	5314309	20	+	28162770	OCIAML3	viability	GAAGTTAAAGGAGAGGGAGGAGG	PROKR2	ENSG00000101292	0.32353019948386375	[26]	[101]	3	hSpCas9	negative selection	12419250
5313941	5313964	20	+	28162770	OCIAML3	viability	GGTGGAGACGTAGAGGGAGACGG	PROKR2	ENSG00000101292	-3.9863250631029237	[20]	[3]	-9	hSpCas9	negative selection	12419251
5314061	5314084	20	+	28162770	OCIAML3	viability	GGCCACCAGGAAGTCGGAGATGG	PROKR2	ENSG00000101292	0.41113566295179665	[69]	[280]	4	hSpCas9	negative selection	12419252
5314246	5314269	20	+	28162770	OCIAML3	viability	CCTCATCCTCATCCATAGGGAGG	PROKR2	ENSG00000101292	-0.08499399283630549	[38]	[110]	0	hSpCas9	negative selection	12419253
5314036	5314059	20	-	28162770	OCIAML3	viability	CATCTGCTGCCCCTTCGAGATGG	PROKR2	ENSG00000101292	-0.8391201381606945	[63]	[107]	-6	hSpCas9	negative selection	12419254
5313920	5313943	20	+	28162770	OCIAML3	viability	GGCAATGGCCAGCAAGGCATTGG	PROKR2	ENSG00000101292	0.568012163032803	[182]	[818]	5	hSpCas9	negative selection	12419255
5314229	5314252	20	-	28162770	OCIAML3	viability	ATGAGGACATGACCAAGACCCGG	PROKR2	ENSG00000101292	0.08269742902456872	[65]	[210]	0	hSpCas9	negative selection	12419256