Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:5627
• Symbol:PROS1
• Description:protein S

DataSource: http://genomecrispr.dkfz.de/#!/results/PROS1

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
93927276	93927299	3	-	26472758	Jiyoye	viability	GTGCAATAAAGAAGAAGCCAGGG	PROS1	ENSG00000184500	0.5944539496984538	[100]	[114]	4	hSpCas9	negative selection	127871
93886347	93886370	3	+	26472758	Jiyoye	viability	GTTCACTTTCCACTTTCCGAGGG	PROS1	ENSG00000184500	-0.29601320067590814	[196]	[120]	-2	hSpCas9	negative selection	127872
93927255	93927278	3	-	26472758	Jiyoye	viability	GGAGGTCTTTGAAAATGACCCGG	PROS1	ENSG00000184500	-1.9913739949844016	[57]	[10]	-8	hSpCas9	negative selection	127873
93884869	93884892	3	+	26472758	Jiyoye	viability	GTATACATCCATCTAGACGAGGG	PROS1	ENSG00000184500	0.07375164778068155	[62]	[49]	0	hSpCas9	negative selection	127874
93876974	93876997	3	-	26472758	Jiyoye	viability	AAAGTGGCCACATACCTGGGTGG	PROS1	ENSG00000184500	0.9076043720153619	[163]	[231]	6	hSpCas9	negative selection	127875
93973724	93973747	3	-	26472758	Jiyoye	viability	AGGGTCCTGGGTGGGCGCTGCGG	PROS1	ENSG00000184500	1.1441409756720797	[11]	[19]	7	hSpCas9	negative selection	127876
93927375	93927398	3	-	26472758	Jiyoye	viability	GCAACAGGCTTCACAAGTCCTGG	PROS1	ENSG00000184500	-0.47631060976770134	[106]	[57]	-3	hSpCas9	negative selection	127877
93879235	93879258	3	+	26472758	Jiyoye	viability	AAGCATAACACCAGTGCCCGTGG	PROS1	ENSG00000184500	1.4672963739434446	[46]	[97]	8	hSpCas9	negative selection	127878
93896616	93896639	3	-	26472758	Jiyoye	viability	CTTGGCGGAGCAGTTTGCAGGGG	PROS1	ENSG00000184500	0.0369258039738678	[295]	[228]	0	hSpCas9	negative selection	127879
93893041	93893064	3	-	26472758	Jiyoye	viability	AATCTATCGATCACTCAGCGTGG	PROS1	ENSG00000184500	-0.26351699324116673	[77]	[48]	-2	hSpCas9	negative selection	127880
93927276	93927299	3	-	26472758	KBM7	viability	GTGCAATAAAGAAGAAGCCAGGG	PROS1	ENSG00000184500	0.2822934916135205	[455,302]	[296,138]	3	hSpCas9	negative selection	318989
93886347	93886370	3	+	26472758	KBM7	viability	GTTCACTTTCCACTTTCCGAGGG	PROS1	ENSG00000184500	-0.26427085994823696	[935,734]	[283,360]	-3	hSpCas9	negative selection	318990
93927255	93927278	3	-	26472758	KBM7	viability	GGAGGTCTTTGAAAATGACCCGG	PROS1	ENSG00000184500	-0.5816743177847401	[173,152]	[45,55]	-5	hSpCas9	negative selection	318991
93884869	93884892	3	+	26472758	KBM7	viability	GTATACATCCATCTAGACGAGGG	PROS1	ENSG00000184500	-0.5830293922371845	[139,145]	[31,56]	-5	hSpCas9	negative selection	318992
93876974	93876997	3	-	26472758	KBM7	viability	AAAGTGGCCACATACCTGGGTGG	PROS1	ENSG00000184500	0.7904817005051605	[774,521]	[529,509]	8	hSpCas9	negative selection	318993
93973724	93973747	3	-	26472758	KBM7	viability	AGGGTCCTGGGTGGGCGCTGCGG	PROS1	ENSG00000184500	-0.08130312105412152	[52,18]	[18,11]	-1	hSpCas9	negative selection	318994
93927375	93927398	3	-	26472758	KBM7	viability	GCAACAGGCTTCACAAGTCCTGG	PROS1	ENSG00000184500	0.5970605679763734	[302,438]	[324,220]	6	hSpCas9	negative selection	318995
93879235	93879258	3	+	26472758	KBM7	viability	AAGCATAACACCAGTGCCCGTGG	PROS1	ENSG00000184500	-0.24905514011341118	[472,301]	[195,109]	-2	hSpCas9	negative selection	318996
93896616	93896639	3	-	26472758	KBM7	viability	CTTGGCGGAGCAGTTTGCAGGGG	PROS1	ENSG00000184500	0.1949368215605476	[1306,896]	[627,545]	2	hSpCas9	negative selection	318997
93893041	93893064	3	-	26472758	KBM7	viability	AATCTATCGATCACTCAGCGTGG	PROS1	ENSG00000184500	0.0008347159980384156	[367,256]	[124,162]	0	hSpCas9	negative selection	318998
93927276	93927299	3	-	26472758	Raji	viability	GTGCAATAAAGAAGAAGCCAGGG	PROS1	ENSG00000184500	0.5675089241809814	[188]	[64]	5	hSpCas9	negative selection	510107
93886347	93886370	3	+	26472758	Raji	viability	GTTCACTTTCCACTTTCCGAGGG	PROS1	ENSG00000184500	-0.11311682662163991	[507]	[108]	-1	hSpCas9	negative selection	510108
93927255	93927278	3	-	26472758	Raji	viability	GGAGGTCTTTGAAAATGACCCGG	PROS1	ENSG00000184500	0.9653645305011715	[63]	[28]	8	hSpCas9	negative selection	510109
93884869	93884892	3	+	26472758	Raji	viability	GTATACATCCATCTAGACGAGGG	PROS1	ENSG00000184500	-3.0625414660687134	[107]	[2]	-9	hSpCas9	negative selection	510110
93876974	93876997	3	-	26472758	Raji	viability	AAAGTGGCCACATACCTGGGTGG	PROS1	ENSG00000184500	0.1180307795731079	[269]	[67]	1	hSpCas9	negative selection	510111
93973724	93973747	3	-	26472758	Raji	viability	AGGGTCCTGGGTGGGCGCTGCGG	PROS1	ENSG00000184500	1.6219567082033572	[6]	[4]	9	hSpCas9	negative selection	510112
93927375	93927398	3	-	26472758	Raji	viability	GCAACAGGCTTCACAAGTCCTGG	PROS1	ENSG00000184500	0.7099044074790604	[244]	[92]	6	hSpCas9	negative selection	510113
93879235	93879258	3	+	26472758	Raji	viability	AAGCATAACACCAGTGCCCGTGG	PROS1	ENSG00000184500	-0.19927780286045227	[281]	[56]	-2	hSpCas9	negative selection	510114
93896616	93896639	3	-	26472758	Raji	viability	CTTGGCGGAGCAGTTTGCAGGGG	PROS1	ENSG00000184500	-0.032405748095394094	[757]	[171]	0	hSpCas9	negative selection	510115
93893041	93893064	3	-	26472758	Raji	viability	AATCTATCGATCACTCAGCGTGG	PROS1	ENSG00000184500	0.4444185226511702	[132]	[41]	4	hSpCas9	negative selection	510116
93927276	93927299	3	-	26472758	K562	viability	GTGCAATAAAGAAGAAGCCAGGG	PROS1	ENSG00000184500	0.3888086370016216	[284]	[314]	3	hSpCas9	negative selection	701225
93886347	93886370	3	+	26472758	K562	viability	GTTCACTTTCCACTTTCCGAGGG	PROS1	ENSG00000184500	0.2976467162417703	[744]	[772]	2	hSpCas9	negative selection	701226
93927255	93927278	3	-	26472758	K562	viability	GGAGGTCTTTGAAAATGACCCGG	PROS1	ENSG00000184500	0.8328871718891384	[136]	[205]	7	hSpCas9	negative selection	701227
93884869	93884892	3	+	26472758	K562	viability	GTATACATCCATCTAGACGAGGG	PROS1	ENSG00000184500	-1.2030402493047747	[89]	[32]	-6	hSpCas9	negative selection	701228
93876974	93876997	3	-	26472758	K562	viability	AAAGTGGCCACATACCTGGGTGG	PROS1	ENSG00000184500	0.8093589249557892	[652]	[965]	6	hSpCas9	negative selection	701229
93973724	93973747	3	-	26472758	K562	viability	AGGGTCCTGGGTGGGCGCTGCGG	PROS1	ENSG00000184500	-0.36563475401754	[28]	[18]	-2	hSpCas9	negative selection	701230
93927375	93927398	3	-	26472758	K562	viability	GCAACAGGCTTCACAAGTCCTGG	PROS1	ENSG00000184500	0.6364950785019794	[284]	[373]	5	hSpCas9	negative selection	701231
93879235	93879258	3	+	26472758	K562	viability	AAGCATAACACCAGTGCCCGTGG	PROS1	ENSG00000184500	1.0105727893602003	[273]	[465]	8	hSpCas9	negative selection	701232
93896616	93896639	3	-	26472758	K562	viability	CTTGGCGGAGCAGTTTGCAGGGG	PROS1	ENSG00000184500	0.410049784575792	[1158]	[1299]	3	hSpCas9	negative selection	701233
93893041	93893064	3	-	26472758	K562	viability	AATCTATCGATCACTCAGCGTGG	PROS1	ENSG00000184500	0.7419183871372637	[271]	[383]	6	hSpCas9	negative selection	701234
93884868	93884891	3	+	26627737	DLD1	viability	CGTATACATCCATCTAGACGAGG	PROS1	ENSG00000184500	-0.5844318002929401	[1092]	[222,268,197]	-5	hSpCas9	negative selection	823147
93884868	93884891	3	+	26627737	GBM cells	viability after 5 days	CGTATACATCCATCTAGACGAGG	PROS1	ENSG00000184500	-0.03773278787004619	[645]	[367,306]	0	hSpCas9	negative selection	905462
93884868	93884891	3	+	26627737	GBM cells	viability after 13 days	CGTATACATCCATCTAGACGAGG	PROS1	ENSG00000184500	-0.13235398401438636	[645]	[364,282]	-2	hSpCas9	negative selection	987777
93884868	93884891	3	+	26627737	GBM cells	viability after 21 days	CGTATACATCCATCTAGACGAGG	PROS1	ENSG00000184500	0.15056937296875428	[645]	[387,390]	1	hSpCas9	negative selection	1070092
93884868	93884891	3	+	26627737	RPE1	viability after 9 days	CGTATACATCCATCTAGACGAGG	PROS1	ENSG00000184500	-0.5925689839181806	[1314]	[310,223]	-4	hSpCas9	negative selection	1152407
93884868	93884891	3	+	26627737	RPE1	viability after 12 days	CGTATACATCCATCTAGACGAGG	PROS1	ENSG00000184500	-0.403576670668668	[1314]	[235,299]	-3	hSpCas9	negative selection	1234722
93884868	93884891	3	+	26627737	RPE1	viability after 15 days	CGTATACATCCATCTAGACGAGG	PROS1	ENSG00000184500	0.02458553248549067	[1314]	[328,425]	0	hSpCas9	negative selection	1317037
93884868	93884891	3	+	26627737	RPE1	viability after 18 days	CGTATACATCCATCTAGACGAGG	PROS1	ENSG00000184500	-0.21077762296799551	[1314]	[266,348]	-1	hSpCas9	negative selection	1399352
93884868	93884891	3	+	26627737	HeLa	viability after 8 days	CGTATACATCCATCTAGACGAGG	PROS1	ENSG00000184500	0.11463814438663045	[800]	[717,406,101]	1	hSpCas9	negative selection	1481667
93884868	93884891	3	+	26627737	HeLa	viability after 12 days	CGTATACATCCATCTAGACGAGG	PROS1	ENSG00000184500	0.2255605508201195	[800]	[570,334,265]	2	hSpCas9	negative selection	1563982
93884868	93884891	3	+	26627737	HeLa	viability after 15 days	CGTATACATCCATCTAGACGAGG	PROS1	ENSG00000184500	0.13574265833776278	[800]	[452,256,363]	1	hSpCas9	negative selection	1646297
93884868	93884891	3	+	26627737	HeLa	viability after 18 days	CGTATACATCCATCTAGACGAGG	PROS1	ENSG00000184500	0.13244633070984535	[800]	[314,196,363]	1	hSpCas9	negative selection	1728612
93884868	93884891	3	+	26627737	HCT116	viability after 6 days	CGTATACATCCATCTAGACGAGG	PROS1	ENSG00000184500	1.3611962500261516	[1334]	[533,541]	7	hSpCas9	negative selection	1810927
93884868	93884891	3	+	26627737	HCT116	viability after 8 days	CGTATACATCCATCTAGACGAGG	PROS1	ENSG00000184500	0.21587129811761052	[658]	[393,389,479]	2	hSpCas9	negative selection	1893242
93884868	93884891	3	+	26627737	HCT116	viability after 9 days	CGTATACATCCATCTAGACGAGG	PROS1	ENSG00000184500	-0.007827421133606682	[1334]	[625,139]	0	hSpCas9	negative selection	1975557
93884868	93884891	3	+	26627737	HCT116	viability after 12 days	CGTATACATCCATCTAGACGAGG	PROS1	ENSG00000184500	0.24484433001365602	[658]	[380,421,430]	2	hSpCas9	negative selection	2057872
93884868	93884891	3	+	26627737	HCT116	viability after 15 days	CGTATACATCCATCTAGACGAGG	PROS1	ENSG00000184500	0.09802731610241433	[658]	[472,471,279]	1	hSpCas9	negative selection	2140187
93884868	93884891	3	+	26627737	HCT116	viability after 18 days	CGTATACATCCATCTAGACGAGG	PROS1	ENSG00000184500	0.27671798725608054	[658]	[448,358,349]	2	hSpCas9	negative selection	2222502
93971314	93971337	3	-	25494202	A375	resistance to PLX-4720 (puromycin)	TTGCCCAGGCTGGAGTGCAGGAG	PROS1	ENSG00000184500	0.9977856233970179	[9,4]	[4,0]	4	dCas9-VP64	positive selection	2435918
93933974	93933997	3	+	25494202	A375	resistance to PLX-4720 (puromycin)	ACTCCAGCCTGGGCGACAGAAAG	PROS1	ENSG00000184500	1.2012671036636573	[14,1]	[1,5]	5	dCas9-VP64	positive selection	2454924
93956370	93956393	3	+	25494202	A375	resistance to PLX-4720 (puromycin)	GCCTGTAGTCCCAGCTACTCAAG	PROS1	ENSG00000184500	0.4848717924049799	[259,492]	[140,88]	2	dCas9-VP64	positive selection	2468633
93895810	93895833	3	+	25494202	A375	resistance to PLX-4720 (puromycin)	CAAAAATTAGCTGGGTGTGGCAG	PROS1	ENSG00000184500	-2.5797701712444865	[504,29]	[12,4]	-9	dCas9-VP64	positive selection	2473382
93971314	93971337	3	-	25494202	A375	resistance to PLX-4720 (zeocin)	TTGCCCAGGCTGGAGTGCAGGAG	PROS1	ENSG00000184500	-0.1814090993543942	[50,40]	[18,6]	-2	dCas9-VP64	positive selection	2531173
93933974	93933997	3	+	25494202	A375	resistance to PLX-4720 (zeocin)	ACTCCAGCCTGGGCGACAGAAAG	PROS1	ENSG00000184500	0.32779538109836626	[14,14]	[4,6]	2	dCas9-VP64	positive selection	2550179
93956370	93956393	3	+	25494202	A375	resistance to PLX-4720 (zeocin)	GCCTGTAGTCCCAGCTACTCAAG	PROS1	ENSG00000184500	0.2857588864060996	[349,998]	[76,442]	2	dCas9-VP64	positive selection	2563888
93895810	93895833	3	+	25494202	A375	resistance to PLX-4720 (zeocin)	CAAAAATTAGCTGGGTGTGGCAG	PROS1	ENSG00000184500	0.3593778947128078	[15,191]	[23,59]	3	dCas9-VP64	positive selection	2568637
93898447	93898470	3	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CCAAGATCAGAAGAGTTGTGAGG	PROS1	ENSG00000184500	0.5002069538822271	[4,4]	[4,6]	8	hSpCas9	positive selection	3013842
93896616	93896639	3	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CTTGGCGGAGCAGTTTGCAGGGG	PROS1	ENSG00000184500	0.13782372643125748	[3,3]	[3,3]	3	hSpCas9	positive selection	3013843
93927276	93927299	3	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GTGCAATAAAGAAGAAGCCAGGG	PROS1	ENSG00000184500	-0.18044592118546227	[2,3]	[4,0]	-3	hSpCas9	positive selection	3013844
93927329	93927352	3	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TTACTTGAAGAAACCAAACAGGG	PROS1	ENSG00000184500	0.03032653428526738	[4,4]	[3,3]	0	hSpCas9	positive selection	3013845
93898447	93898470	3	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CCAAGATCAGAAGAGTTGTGAGG	PROS1	ENSG00000184500	1.0302215608092915	[4,4]	[7,7]	9	hSpCas9	positive selection	3081700
93896616	93896639	3	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CTTGGCGGAGCAGTTTGCAGGGG	PROS1	ENSG00000184500	-0.6727179201035967	[3,3]	[2,0]	-8	hSpCas9	positive selection	3081701
93927276	93927299	3	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GTGCAATAAAGAAGAAGCCAGGG	PROS1	ENSG00000184500	0.8741939213589512	[2,2]	[4,4]	9	hSpCas9	positive selection	3081702
93927329	93927352	3	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TTACTTGAAGAAACCAAACAGGG	PROS1	ENSG00000184500	-0.09565379866405402	[4,4]	[4,1]	-1	hSpCas9	positive selection	3081703
93973680	93973703		-	24336571	A375	resistance to PLX after 7 days	CCTAGTGCTTCCCGTCTCAGAGG	PROS1	ENSG00000184500	-0.1315272718740943	[14,12]	[13,11]	-4	hSpCas9	positive selection	3137961
93973737	93973760		-	24336571	A375	resistance to PLX after 7 days	GCGCTTCGAAATGAGGGTCCTGG	PROS1	ENSG00000184500	-0.038972064552209584	[5,5]	[4,6]	-1	hSpCas9	positive selection	3137963
93910681	93910704		-	24336571	A375	resistance to PLX after 7 days	TGTCTTCGCTCTTTTCAAACTGG	PROS1	ENSG00000184500	0.07515489493048066	[5,7]	[6,7]	2	hSpCas9	positive selection	3137964
93973680	93973703		-	24336571	A375	resistance to PLX after 14 days	CCTAGTGCTTCCCGTCTCAGAGG	PROS1	ENSG00000184500	0.5281968297653865	[11,15]	[7,10]	5	hSpCas9	positive selection	3195754
93973737	93973760		-	24336571	A375	resistance to PLX after 14 days	GCGCTTCGAAATGAGGGTCCTGG	PROS1	ENSG00000184500	0.4421718832164624	[4,5]	[3,2]	4	hSpCas9	positive selection	3195756
93910681	93910704		-	24336571	A375	resistance to PLX after 14 days	TGTCTTCGCTCTTTTCAAACTGG	PROS1	ENSG00000184500	-0.424915215957374	[10,6]	[2,2]	-5	hSpCas9	positive selection	3195757
93973680	93973703		-	24336571	A375	viability after 7 days	CCTAGTGCTTCCCGTCTCAGAGG	PROS1	ENSG00000184500	0.23119266429584018	[12]	[14,12]	3	hSpCas9	negative selection	3253547
93973737	93973760		-	24336571	A375	viability after 7 days	GCGCTTCGAAATGAGGGTCCTGG	PROS1	ENSG00000184500	0.015901609444753495	[5]	[5,5]	0	hSpCas9	negative selection	3253549
93910681	93910704		-	24336571	A375	viability after 7 days	TGTCTTCGCTCTTTTCAAACTGG	PROS1	ENSG00000184500	-0.47196123906156795	[9]	[5,7]	-6	hSpCas9	negative selection	3253550
93973680	93973703		-	24336571	A375	viability after 14 days	CCTAGTGCTTCCCGTCTCAGAGG	PROS1	ENSG00000184500	0.18942169948937737	[12]	[11,15]	2	hSpCas9	negative selection	3311340
93973737	93973760		-	24336571	A375	viability after 14 days	GCGCTTCGAAATGAGGGTCCTGG	PROS1	ENSG00000184500	-0.1660119023787765	[5]	[4,5]	-2	hSpCas9	negative selection	3311342
93910681	93910704		-	24336571	A375	viability after 14 days	TGTCTTCGCTCTTTTCAAACTGG	PROS1	ENSG00000184500	-0.09884941725420282	[9]	[10,6]	-1	hSpCas9	negative selection	3311343
93906095	93906118	3	+	27383988	293T	resistance to West Nile virus (flavivirus)	ATATATCCATCTTCATTGCATGG	PROS1	ENSG00000184500	-1.1263780810282171	[333,333]	[0,0]	-7	hSpCas9	positive selection	3387624
93910616	93910639	3	+	27383988	293T	resistance to West Nile virus (flavivirus)	TACCATTGACACAGCTTCTTAGG	PROS1	ENSG00000184500	-0.6910410201388426	[246,246]	[0,0]	-5	hSpCas9	positive selection	3387625
93910618	93910641	3	-	27383988	293T	resistance to West Nile virus (flavivirus)	GACCTAAGAAGCTGTGTCAATGG	PROS1	ENSG00000184500	0.15929412848530838	[136,136]	[0,0]	0	hSpCas9	positive selection	3387626
93898447	93898470	3	-	26780180	HT29	viability (Avana library 4 designs)	CCAAGATCAGAAGAGTTGTGAGG	PROS1	ENSG00000184500	1.10284322393186	[]	[]	4	hSpCas9	negative selection	3452037
93896616	93896639	3	-	26780180	HT29	viability (Avana library 4 designs)	CTTGGCGGAGCAGTTTGCAGGGG	PROS1	ENSG00000184500	1.89131222439364	[]	[]	7	hSpCas9	negative selection	3452038
93927276	93927299	3	-	26780180	HT29	viability (Avana library 4 designs)	GTGCAATAAAGAAGAAGCCAGGG	PROS1	ENSG00000184500	0.859615262834714	[]	[]	3	hSpCas9	negative selection	3452039
93927329	93927352	3	-	26780180	HT29	viability (Avana library 4 designs)	TTACTTGAAGAAACCAAACAGGG	PROS1	ENSG00000184500	0.678787508320827	[]	[]	2	hSpCas9	negative selection	3452040
93927329	93927352	3	-	26780180	A375	viability (Avana lentiCRISPRv2)	TTACTTGAAGAAACCAAACAGGG	PROS1	ENSG00000184500	-13.1098819320275	[]	[]	-8	hSpCas9	negative selection	3548216
93927276	93927299	3	-	26780180	A375	viability (Avana lentiCRISPRv2)	GTGCAATAAAGAAGAAGCCAGGG	PROS1	ENSG00000184500	-2.30466840239498	[]	[]	-3	hSpCas9	negative selection	3548217
93896616	93896639	3	-	26780180	A375	viability (Avana lentiCRISPRv2)	CTTGGCGGAGCAGTTTGCAGGGG	PROS1	ENSG00000184500	0.308024078136639	[]	[]	0	hSpCas9	negative selection	3548218
93898447	93898470	3	-	26780180	A375	viability (Avana lentiCRISPRv2)	CCAAGATCAGAAGAGTTGTGAGG	PROS1	ENSG00000184500	-0.128777473996938	[]	[]	0	hSpCas9	negative selection	3548219
93905876	93905899	3	-	26780180	A375	viability (Avana lentiCRISPRv2)	GATCCCTCAAATATAAATGGAGG	PROS1	ENSG00000184500	-11.7193101592739	[]	[]	-8	hSpCas9	negative selection	3548220
93906101	93906124	3	+	26780180	A375	viability (Avana lentiCRISPRv2)	CCATCTTCATTGCATGGCAGAGG	PROS1	ENSG00000184500	4.65948733960945	[]	[]	7	hSpCas9	negative selection	3548221
93927329	93927352	3	-	26780180	A375	viability (Avana lentiGuide)	TTACTTGAAGAAACCAAACAGGG	PROS1	ENSG00000184500	5.15322380241879	[]	[]	4	hSpCas9	negative selection	3656875
93927276	93927299	3	-	26780180	A375	viability (Avana lentiGuide)	GTGCAATAAAGAAGAAGCCAGGG	PROS1	ENSG00000184500	2.178750402943	[]	[]	2	hSpCas9	negative selection	3656876
93896616	93896639	3	-	26780180	A375	viability (Avana lentiGuide)	CTTGGCGGAGCAGTTTGCAGGGG	PROS1	ENSG00000184500	1.40075487487402	[]	[]	1	hSpCas9	negative selection	3656877
93898447	93898470	3	-	26780180	A375	viability (Avana lentiGuide)	CCAAGATCAGAAGAGTTGTGAGG	PROS1	ENSG00000184500	1.39700920944674	[]	[]	1	hSpCas9	negative selection	3656878
93905876	93905899	3	-	26780180	A375	viability (Avana lentiGuide)	GATCCCTCAAATATAAATGGAGG	PROS1	ENSG00000184500	9.71745897997996	[]	[]	6	hSpCas9	negative selection	3656879
93906101	93906124	3	+	26780180	A375	viability (Avana lentiGuide)	CCATCTTCATTGCATGGCAGAGG	PROS1	ENSG00000184500	1.0209124359613	[]	[]	1	hSpCas9	negative selection	3656880
93927329	93927352	3	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TTACTTGAAGAAACCAAACAGGG	PROS1	ENSG00000184500	-0.864987553507664	[8]	[4,2]	-8	hSpCas9	positive selection	3765482
93927276	93927299	3	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GTGCAATAAAGAAGAAGCCAGGG	PROS1	ENSG00000184500	-0.4210210645537588	[5]	[3,3]	-6	hSpCas9	positive selection	3765483
93896616	93896639	3	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CTTGGCGGAGCAGTTTGCAGGGG	PROS1	ENSG00000184500	-0.16497758625577322	[5]	[5,3]	-3	hSpCas9	positive selection	3765484
93898447	93898470	3	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CCAAGATCAGAAGAGTTGTGAGG	PROS1	ENSG00000184500	0.17416099721393535	[6]	[6,7]	5	hSpCas9	positive selection	3765485
93905876	93905899	3	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GATCCCTCAAATATAAATGGAGG	PROS1	ENSG00000184500	-0.9831710609511588	[7]	[3,3]	-8	hSpCas9	positive selection	3765486
93906101	93906124	3	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CCATCTTCATTGCATGGCAGAGG	PROS1	ENSG00000184500	0.20365077561968842	[4]	[5,4]	5	hSpCas9	positive selection	3765487
93927329	93927352	3	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TTACTTGAAGAAACCAAACAGGG	PROS1	ENSG00000184500	-0.029610210441550766	[6]	[6,4]	0	hSpCas9	positive selection	3874089
93927276	93927299	3	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GTGCAATAAAGAAGAAGCCAGGG	PROS1	ENSG00000184500	-0.18631499536357124	[5]	[3,3]	-3	hSpCas9	positive selection	3874090
93896616	93896639	3	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CTTGGCGGAGCAGTTTGCAGGGG	PROS1	ENSG00000184500	-0.7304044042314655	[5]	[1,2]	-7	hSpCas9	positive selection	3874091
93898447	93898470	3	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CCAAGATCAGAAGAGTTGTGAGG	PROS1	ENSG00000184500	0.18466524409492058	[6]	[6,6]	4	hSpCas9	positive selection	3874092
93905876	93905899	3	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GATCCCTCAAATATAAATGGAGG	PROS1	ENSG00000184500	-1.6299602551145247	[5]	[0,0]	-9	hSpCas9	positive selection	3874093
93906101	93906124	3	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CCATCTTCATTGCATGGCAGAGG	PROS1	ENSG00000184500	-0.44244151278914456	[4]	[1,3]	-5	hSpCas9	positive selection	3874094
93906095	93906118	3	+	26780180	A375	viability	ATATATCCATCTTCATTGCATGG	PROS1	ENSG00000184500	0.83263612851238	[]	[]	3	hSpCas9	negative selection	3984550
93973680	93973703	3	-	26780180	A375	viability	CCTAGTGCTTCCCGTCTCAGAGG	PROS1	ENSG00000184500	1.00170549408176	[]	[]	4	hSpCas9	negative selection	3984551
93973737	93973760	3	-	26780180	A375	viability	GCGCTTCGAAATGAGGGTCCTGG	PROS1	ENSG00000184500	0.975622606673024	[]	[]	4	hSpCas9	negative selection	3984552
93906047	93906070	3	-	26780180	A375	viability	TTTACTTGCACTTGTAAACCAGG	PROS1	ENSG00000184500	1.273049080021	[]	[]	7	hSpCas9	negative selection	3984553
93906095	93906118	3	+	26780180	HT29	viability (GeCKOv2 library)	ATATATCCATCTTCATTGCATGG	PROS1	ENSG00000184500	0.828027817457825	[]	[]	3	hSpCas9	negative selection	4092516
93973680	93973703	3	-	26780180	HT29	viability (GeCKOv2 library)	CCTAGTGCTTCCCGTCTCAGAGG	PROS1	ENSG00000184500	1.52645088501558	[]	[]	7	hSpCas9	negative selection	4092517
93973737	93973760	3	-	26780180	HT29	viability (GeCKOv2 library)	GCGCTTCGAAATGAGGGTCCTGG	PROS1	ENSG00000184500	1.45117826628893	[]	[]	7	hSpCas9	negative selection	4092518
93906047	93906070	3	-	26780180	HT29	viability (GeCKOv2 library)	TTTACTTGCACTTGTAAACCAGG	PROS1	ENSG00000184500	1.659768409334	[]	[]	8	hSpCas9	negative selection	4092519
93973680	93973703	3	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CCTAGTGCTTCCCGTCTCAGAGG	PROS1	ENSG00000184500	0.05374859895896218	[3]	[1,3]	1	hSpCas9	positive selection	4163133
93973737	93973760	3	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GCGCTTCGAAATGAGGGTCCTGG	PROS1	ENSG00000184500	-0.08511324102692153	[2]	[0,1]	-2	hSpCas9	positive selection	4163135
93910681	93910704	3	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TGTCTTCGCTCTTTTCAAACTGG	PROS1	ENSG00000184500	-0.25601501813014915	[2]	[1,1]	-6	hSpCas9	positive selection	4163136
93973680	93973703	3	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CCTAGTGCTTCCCGTCTCAGAGG	PROS1	ENSG00000184500	0.5187359322237026	[2]	[3,0,4,0]	3	hSpCas9	positive selection	4227155
93973737	93973760	3	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GCGCTTCGAAATGAGGGTCCTGG	PROS1	ENSG00000184500	-0.6739401346758377	[2]	[0,0,0,0]	-8	hSpCas9	positive selection	4227157
93910681	93910704	3	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TGTCTTCGCTCTTTTCAAACTGG	PROS1	ENSG00000184500	1.07424298351049	[1]	[3,2,1,0]	7	hSpCas9	positive selection	4227158
93973737	93973760	3	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GCGCTTCGAAATGAGGGTCCTGG	PROS1	ENSG00000184500	-0.3753515249940783	[1]	[1,0]	-7	hSpCas9	positive selection	4292323
93973680	93973703	3	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCTAGTGCTTCCCGTCTCAGAGG	PROS1	ENSG00000184500	0.020344165988199436	[3]	[2,2]	0	hSpCas9	positive selection	4292324
93906047	93906070	3	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TTTACTTGCACTTGTAAACCAGG	PROS1	ENSG00000184500	-0.3579670825953024	[2]	[1,0]	-6	hSpCas9	positive selection	4292325
93906095	93906118	3	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ATATATCCATCTTCATTGCATGG	PROS1	ENSG00000184500	0.4748556221449509	[3]	[3,4]	8	hSpCas9	positive selection	4356582
93906047	93906069	3	-	27760321	OCIAML3	viability	TTACTTGCACTTGTAAACCAGG	PROS1	ENSG00000184500	0.009350974666589407	[142,126]	[86,130]	0	hSpCas9	negative selection	4430825
93927358	93927380	3	+	27760321	OCIAML3	viability	TGCACGACGCTTCCTAACCAGG	PROS1	ENSG00000184500	0.2206119421987106	[714,626]	[436,835]	2	hSpCas9	negative selection	4430826
93893081	93893103	3	-	27760321	OCIAML3	viability	TCCGGACATATGATTCAGAAGG	PROS1	ENSG00000184500	0.42953964577722104	[252,179]	[242,202]	5	hSpCas9	negative selection	4430827
93898515	93898537	3	-	27760321	OCIAML3	viability	AGCTTTGTGTCAATTACCCTGG	PROS1	ENSG00000184500	-0.4176956168094284	[437,422]	[222,290]	-4	hSpCas9	negative selection	4430828
93900839	93900861	3	-	27760321	OCIAML3	viability	TTGAATGTGAATGCCCCGAAGG	PROS1	ENSG00000184500	-0.2915734087620169	[534,477]	[261,402]	-3	hSpCas9	negative selection	4430829
93906047	93906069	3	-	27760321	OCIAML2	viability	TTACTTGCACTTGTAAACCAGG	PROS1	ENSG00000184500	0.2850271034861227	[142,126]	[153,104]	4	hSpCas9	negative selection	4514288
93927358	93927380	3	+	27760321	OCIAML2	viability	TGCACGACGCTTCCTAACCAGG	PROS1	ENSG00000184500	0.10187329565838088	[714,626]	[598,557]	1	hSpCas9	negative selection	4514289
93893081	93893103	3	-	27760321	OCIAML2	viability	TCCGGACATATGATTCAGAAGG	PROS1	ENSG00000184500	0.11485180995587485	[252,179]	[175,202]	1	hSpCas9	negative selection	4514290
93898515	93898537	3	-	27760321	OCIAML2	viability	AGCTTTGTGTCAATTACCCTGG	PROS1	ENSG00000184500	-0.26783102536371384	[437,422]	[278,303]	-3	hSpCas9	negative selection	4514291
93900839	93900861	3	-	27760321	OCIAML2	viability	TTGAATGTGAATGCCCCGAAGG	PROS1	ENSG00000184500	-0.12157029318041172	[534,477]	[357,399]	-1	hSpCas9	negative selection	4514292
93906047	93906069	3	-	27760321	MV411	viability	TTACTTGCACTTGTAAACCAGG	PROS1	ENSG00000184500	0.5717846992528743	[142,126]	[138,121]	4	hSpCas9	negative selection	4597751
93927358	93927380	3	+	27760321	MV411	viability	TGCACGACGCTTCCTAACCAGG	PROS1	ENSG00000184500	0.3887613342301415	[714,626]	[721,362]	2	hSpCas9	negative selection	4597752
93893081	93893103	3	-	27760321	MV411	viability	TCCGGACATATGATTCAGAAGG	PROS1	ENSG00000184500	-0.04819320876331523	[252,179]	[35,287]	0	hSpCas9	negative selection	4597753
93898515	93898537	3	-	27760321	MV411	viability	AGCTTTGTGTCAATTACCCTGG	PROS1	ENSG00000184500	-1.0680238057863312	[437,422]	[78,220]	-6	hSpCas9	negative selection	4597754
93900839	93900861	3	-	27760321	MV411	viability	TTGAATGTGAATGCCCCGAAGG	PROS1	ENSG00000184500	0.6739979248479224	[534,477]	[488,597]	5	hSpCas9	negative selection	4597755
93906047	93906069	3	-	27760321	HL60	viability	TTACTTGCACTTGTAAACCAGG	PROS1	ENSG00000184500	-0.3624391666662645	[142,126]	[106,62]	-4	hSpCas9	negative selection	4681214
93927358	93927380	3	+	27760321	HL60	viability	TGCACGACGCTTCCTAACCAGG	PROS1	ENSG00000184500	0.10143461369070395	[714,626]	[530,645]	1	hSpCas9	negative selection	4681215
93893081	93893103	3	-	27760321	HL60	viability	TCCGGACATATGATTCAGAAGG	PROS1	ENSG00000184500	1.0692372763443214	[252,179]	[339,395]	9	hSpCas9	negative selection	4681216
93898515	93898537	3	-	27760321	HL60	viability	AGCTTTGTGTCAATTACCCTGG	PROS1	ENSG00000184500	-0.43460914944945767	[437,422]	[249,271]	-5	hSpCas9	negative selection	4681217
93900839	93900861	3	-	27760321	HL60	viability	TTGAATGTGAATGCCCCGAAGG	PROS1	ENSG00000184500	0.6201104638102878	[534,477]	[587,684]	7	hSpCas9	negative selection	4681218
93906047	93906069	3	-	27760321	HT1080	viability	TTACTTGCACTTGTAAACCAGG	PROS1	ENSG00000184500	0.12389060292087084	[126,98]	[28,70]	0	hSpCas9	negative selection	4764677
93927358	93927380	3	+	27760321	HT1080	viability	TGCACGACGCTTCCTAACCAGG	PROS1	ENSG00000184500	-1.4923322484822024	[626,488]	[36,124]	-5	hSpCas9	negative selection	4764678
93893081	93893103	3	-	27760321	HT1080	viability	TCCGGACATATGATTCAGAAGG	PROS1	ENSG00000184500	2.473004017959094	[179,140]	[640,41]	9	hSpCas9	negative selection	4764679
93898515	93898537	3	-	27760321	HT1080	viability	AGCTTTGTGTCAATTACCCTGG	PROS1	ENSG00000184500	0.5012112914836752	[422,329]	[133,297]	2	hSpCas9	negative selection	4764680
93900839	93900861	3	-	27760321	HT1080	viability	TTGAATGTGAATGCCCCGAAGG	PROS1	ENSG00000184500	-2.769392740939228	[477,372]	[42,4]	-7	hSpCas9	negative selection	4764681
93906047	93906069	3	-	27760321	HT29	viability after 7 days	TTACTTGCACTTGTAAACCAGG	PROS1	ENSG00000184500	-0.7743813581835637	[126,98]	[69,111,70]	-8	hSpCas9	negative selection	4848140
93927358	93927380	3	+	27760321	HT29	viability after 7 days	TGCACGACGCTTCCTAACCAGG	PROS1	ENSG00000184500	-0.03480888069094967	[626,488]	[684,785,628]	0	hSpCas9	negative selection	4848141
93893081	93893103	3	-	27760321	HT29	viability after 7 days	TCCGGACATATGATTCAGAAGG	PROS1	ENSG00000184500	0.32423252774046596	[179,140]	[233,329,208]	5	hSpCas9	negative selection	4848142
93898515	93898537	3	-	27760321	HT29	viability after 7 days	AGCTTTGTGTCAATTACCCTGG	PROS1	ENSG00000184500	-0.7559940995040981	[422,329]	[385,275,213]	-8	hSpCas9	negative selection	4848143
93900839	93900861	3	-	27760321	HT29	viability after 7 days	TTGAATGTGAATGCCCCGAAGG	PROS1	ENSG00000184500	-0.19236712746628828	[477,372]	[630,336,488]	-3	hSpCas9	negative selection	4848144
93906047	93906069	3	-	27760321	HT29	viability after 25 days	TTACTTGCACTTGTAAACCAGG	PROS1	ENSG00000184500	-0.39133555974404244	[126,98]	[102,109,79]	-4	hSpCas9	negative selection	4931603
93927358	93927380	3	+	27760321	HT29	viability after 25 days	TGCACGACGCTTCCTAACCAGG	PROS1	ENSG00000184500	0.24176694040542746	[626,488]	[645,838,785]	2	hSpCas9	negative selection	4931604
93893081	93893103	3	-	27760321	HT29	viability after 25 days	TCCGGACATATGATTCAGAAGG	PROS1	ENSG00000184500	0.3827984335673601	[179,140]	[191,273,255]	4	hSpCas9	negative selection	4931605
93898515	93898537	3	-	27760321	HT29	viability after 25 days	AGCTTTGTGTCAATTACCCTGG	PROS1	ENSG00000184500	-0.6018264456711737	[422,329]	[169,379,309]	-5	hSpCas9	negative selection	4931606
93900839	93900861	3	-	27760321	HT29	viability after 25 days	TTGAATGTGAATGCCCCGAAGG	PROS1	ENSG00000184500	-0.39369181848866436	[477,372]	[248,467,403]	-4	hSpCas9	negative selection	4931607
93906047	93906069	3	-	27760321	HT29	viability after 22 days	TTACTTGCACTTGTAAACCAGG	PROS1	ENSG00000184500	-0.6261645736855583	[126,98]	[117,48,85]	-5	hSpCas9	negative selection	5015066
93927358	93927380	3	+	27760321	HT29	viability after 22 days	TGCACGACGCTTCCTAACCAGG	PROS1	ENSG00000184500	0.5075306307182375	[626,488]	[1069,848,826]	5	hSpCas9	negative selection	5015067
93893081	93893103	3	-	27760321	HT29	viability after 22 days	TCCGGACATATGATTCAGAAGG	PROS1	ENSG00000184500	-0.47557916934881117	[179,140]	[49,183,168]	-4	hSpCas9	negative selection	5015068
93898515	93898537	3	-	27760321	HT29	viability after 22 days	AGCTTTGTGTCAATTACCCTGG	PROS1	ENSG00000184500	-0.42452063241001553	[422,329]	[308,368,294]	-4	hSpCas9	negative selection	5015069
93900839	93900861	3	-	27760321	HT29	viability after 22 days	TTGAATGTGAATGCCCCGAAGG	PROS1	ENSG00000184500	-0.7728136684826071	[477,372]	[201,374,288]	-6	hSpCas9	negative selection	5015070
93906047	93906069	3	-	27760321	HT29	viability after 19 days	TTACTTGCACTTGTAAACCAGG	PROS1	ENSG00000184500	-1.288160009697747	[126,98]	[58,64,35]	-7	hSpCas9	negative selection	5098529
93927358	93927380	3	+	27760321	HT29	viability after 19 days	TGCACGACGCTTCCTAACCAGG	PROS1	ENSG00000184500	0.3894852648153373	[626,488]	[588,1207,689]	4	hSpCas9	negative selection	5098530
93893081	93893103	3	-	27760321	HT29	viability after 19 days	TCCGGACATATGATTCAGAAGG	PROS1	ENSG00000184500	0.7043934177023321	[179,140]	[249,418,225]	7	hSpCas9	negative selection	5098531
93898515	93898537	3	-	27760321	HT29	viability after 19 days	AGCTTTGTGTCAATTACCCTGG	PROS1	ENSG00000184500	-1.0343112970590569	[422,329]	[137,274,209]	-6	hSpCas9	negative selection	5098532
93900839	93900861	3	-	27760321	HT29	viability after 19 days	TTGAATGTGAATGCCCCGAAGG	PROS1	ENSG00000184500	-0.38307892545046907	[477,372]	[263,342,495]	-4	hSpCas9	negative selection	5098533
93906047	93906069	3	-	27760321	HT29	viability after 16 days	TTACTTGCACTTGTAAACCAGG	PROS1	ENSG00000184500	-0.41931997281953537	[126,98]	[71,149,57]	-4	hSpCas9	negative selection	5181992
93927358	93927380	3	+	27760321	HT29	viability after 16 days	TGCACGACGCTTCCTAACCAGG	PROS1	ENSG00000184500	0.07643997856608453	[626,488]	[796,531,661]	0	hSpCas9	negative selection	5181993
93893081	93893103	3	-	27760321	HT29	viability after 16 days	TCCGGACATATGATTCAGAAGG	PROS1	ENSG00000184500	0.623582907988117	[179,140]	[249,337,237]	7	hSpCas9	negative selection	5181994
93898515	93898537	3	-	27760321	HT29	viability after 16 days	AGCTTTGTGTCAATTACCCTGG	PROS1	ENSG00000184500	-1.0457387935061966	[422,329]	[141,288,172]	-7	hSpCas9	negative selection	5181995
93900839	93900861	3	-	27760321	HT29	viability after 16 days	TTGAATGTGAATGCCCCGAAGG	PROS1	ENSG00000184500	-0.1951255094962584	[477,372]	[447,432,368]	-2	hSpCas9	negative selection	5181996
93906047	93906069	3	-	27760321	HT29	viability after 13 days	TTACTTGCACTTGTAAACCAGG	PROS1	ENSG00000184500	-0.6389692626843151	[126,98]	[93,99,59]	-6	hSpCas9	negative selection	5265455
93927358	93927380	3	+	27760321	HT29	viability after 13 days	TGCACGACGCTTCCTAACCAGG	PROS1	ENSG00000184500	0.17718518085900925	[626,488]	[699,752,741]	2	hSpCas9	negative selection	5265456
93893081	93893103	3	-	27760321	HT29	viability after 13 days	TCCGGACATATGATTCAGAAGG	PROS1	ENSG00000184500	0.2587779463134853	[179,140]	[248,172,244]	3	hSpCas9	negative selection	5265457
93898515	93898537	3	-	27760321	HT29	viability after 13 days	AGCTTTGTGTCAATTACCCTGG	PROS1	ENSG00000184500	-1.1907594971062536	[422,329]	[109,252,209]	-8	hSpCas9	negative selection	5265458
93900839	93900861	3	-	27760321	HT29	viability after 13 days	TTGAATGTGAATGCCCCGAAGG	PROS1	ENSG00000184500	-0.10341023307302447	[477,372]	[559,424,396]	-1	hSpCas9	negative selection	5265459
93906047	93906069	3	-	27760321	HT29	viability after 10 days	TTACTTGCACTTGTAAACCAGG	PROS1	ENSG00000184500	-0.614961527472567	[126,98]	[99,101,74]	-6	hSpCas9	negative selection	5348918
93927358	93927380	3	+	27760321	HT29	viability after 10 days	TGCACGACGCTTCCTAACCAGG	PROS1	ENSG00000184500	0.14619309338720643	[626,488]	[699,927,690]	2	hSpCas9	negative selection	5348919
93893081	93893103	3	-	27760321	HT29	viability after 10 days	TCCGGACATATGATTCAGAAGG	PROS1	ENSG00000184500	0.16228828148562213	[179,140]	[127,289,255]	2	hSpCas9	negative selection	5348920
93898515	93898537	3	-	27760321	HT29	viability after 10 days	AGCTTTGTGTCAATTACCCTGG	PROS1	ENSG00000184500	-1.0063038965821294	[422,329]	[287,189,222]	-8	hSpCas9	negative selection	5348921
93900839	93900861	3	-	27760321	HT29	viability after 10 days	TTGAATGTGAATGCCCCGAAGG	PROS1	ENSG00000184500	-0.07610350970885585	[477,372]	[629,531,353]	-1	hSpCas9	negative selection	5348922
93906047	93906069	3	-	27760321	MOLM13	viability	TTACTTGCACTTGTAAACCAGG	PROS1	ENSG00000184500	0.5775203669378772	[142,126]	[106,118]	4	hSpCas9	negative selection	5432381
93927358	93927380	3	+	27760321	MOLM13	viability	TGCACGACGCTTCCTAACCAGG	PROS1	ENSG00000184500	0.09607731970182809	[714,626]	[419,389]	0	hSpCas9	negative selection	5432382
93893081	93893103	3	-	27760321	MOLM13	viability	TCCGGACATATGATTCAGAAGG	PROS1	ENSG00000184500	-0.9334299782487705	[252,179]	[119,14]	-5	hSpCas9	negative selection	5432383
93898515	93898537	3	-	27760321	MOLM13	viability	AGCTTTGTGTCAATTACCCTGG	PROS1	ENSG00000184500	0.6395611741850403	[437,422]	[572,213]	4	hSpCas9	negative selection	5432384
93900839	93900861	3	-	27760321	MOLM13	viability	TTGAATGTGAATGCCCCGAAGG	PROS1	ENSG00000184500	1.1089579358955302	[534,477]	[540,678]	7	hSpCas9	negative selection	5432385
93973437	93973460	3	+	27661255	K562	viability	GGTTCTTAGATCTGTCCTGTAGG	PROS1	ENSG00000184500	-0.15700727437849005	[426,443]	[334,291]	-5	dCas9-KRAB	negative selection	5504362
93973844	93973867	3	+	27661255	K562	viability	GTCTGAGCCGTGCTGCGCGGCGG	PROS1	ENSG00000184500	0.12847324751668565	[760,888]	[780,664]	4	dCas9-KRAB	negative selection	5504363
93973868	93973891	3	+	27661255	K562	viability	GCCAGCGACCCAGCGAGCCTCGG	PROS1	ENSG00000184500	0.6478356970849859	[185,262]	[248,304]	9	dCas9-KRAB	negative selection	5504364
93973496	93973519	3	-	27661255	K562	viability	GAGCAGGCAGTGCAATGGTGGGG	PROS1	ENSG00000184500	0.06732558817311199	[834,743]	[693,634]	2	dCas9-KRAB	negative selection	5504365
93973512	93973535	3	-	27661255	K562	viability	GAAACAGCCGTGGATAGAGCAGG	PROS1	ENSG00000184500	0.019865164238662414	[563,565]	[510,411]	0	dCas9-KRAB	negative selection	5504366
93973839	93973862	3	-	27661255	K562	viability	GCGCAGCACGGCTCAGACCGAGG	PROS1	ENSG00000184500	-0.11030919305760042	[704,845]	[605,542]	-4	dCas9-KRAB	negative selection	5504367
93973737	93973760	3	-	27260156	BXPC3	viability	GCGCTTCGAAATGAGGGTCCTGG	PROS1	ENSG00000184500	-0.013090937342145281	[153]	[153,134,180,170]	0	hSpCas9	negative selection	5564783
93973680	93973703	3	-	27260156	BXPC3	viability	CCTAGTGCTTCCCGTCTCAGAGG	PROS1	ENSG00000184500	0.16245426865044027	[626]	[723,735,724,746]	3	hSpCas9	negative selection	5564784
93906047	93906070	3	-	27260156	BXPC3	viability	TTTACTTGCACTTGTAAACCAGG	PROS1	ENSG00000184500	0.4801969552718875	[385]	[666,587,432,541]	8	hSpCas9	negative selection	5564785
93906095	93906118	3	+	27260156	BXPC3	viability	ATATATCCATCTTCATTGCATGG	PROS1	ENSG00000184500	0.0576921150937576	[889]	[828,1024,824,1229]	1	hSpCas9	negative selection	5629042
93973737	93973760	3	-	27260156	A673	viability	GCGCTTCGAAATGAGGGTCCTGG	PROS1	ENSG00000184500	0.08262342435346826	[153]	[212,136,195,242]	2	hSpCas9	negative selection	5686034
93973680	93973703	3	-	27260156	A673	viability	CCTAGTGCTTCCCGTCTCAGAGG	PROS1	ENSG00000184500	0.1474322474820558	[626]	[789,788,713,1049]	3	hSpCas9	negative selection	5686035
93906047	93906070	3	-	27260156	A673	viability	TTTACTTGCACTTGTAAACCAGG	PROS1	ENSG00000184500	0.19851769255229815	[385]	[561,573,495,494]	5	hSpCas9	negative selection	5686036
93906095	93906118	3	+	27260156	A673	viability	ATATATCCATCTTCATTGCATGG	PROS1	ENSG00000184500	0.03410722886520756	[889]	[1391,1000,1027,984]	0	hSpCas9	negative selection	5750293
93973737	93973760	3	-	27260156	A375	viability	GCGCTTCGAAATGAGGGTCCTGG	PROS1	ENSG00000184500	-0.6072995706315798	[153]	[102,193,36,144]	-7	hSpCas9	negative selection	5807285
93973680	93973703	3	-	27260156	A375	viability	CCTAGTGCTTCCCGTCTCAGAGG	PROS1	ENSG00000184500	-0.06962723330996928	[626]	[598,775,903,538]	-1	hSpCas9	negative selection	5807286
93906047	93906070	3	-	27260156	A375	viability	TTTACTTGCACTTGTAAACCAGG	PROS1	ENSG00000184500	0.4069450106115674	[385]	[629,679,562,534]	6	hSpCas9	negative selection	5807287
93906095	93906118	3	+	27260156	A375	viability	ATATATCCATCTTCATTGCATGG	PROS1	ENSG00000184500	0.11383992863219528	[889]	[1142,1336,1236,841]	1	hSpCas9	negative selection	5871544
93973737	93973760	3	-	27260156	COLO741	viability	GCGCTTCGAAATGAGGGTCCTGG	PROS1	ENSG00000184500	-0.366337060854381	[153]	[146,127,179]	-7	hSpCas9	negative selection	5928536
93973680	93973703	3	-	27260156	COLO741	viability	CCTAGTGCTTCCCGTCTCAGAGG	PROS1	ENSG00000184500	0.2843532260790938	[626]	[1090,904,940]	6	hSpCas9	negative selection	5928537
93906047	93906070	3	-	27260156	COLO741	viability	TTTACTTGCACTTGTAAACCAGG	PROS1	ENSG00000184500	0.25754357829483776	[385]	[697,538,542]	5	hSpCas9	negative selection	5928538
93906095	93906118	3	+	27260156	COLO741	viability	ATATATCCATCTTCATTGCATGG	PROS1	ENSG00000184500	0.2749170338246637	[889]	[1442,1504,1195]	6	hSpCas9	negative selection	5992795
93973737	93973760	3	-	27260156	CAL120	viability	GCGCTTCGAAATGAGGGTCCTGG	PROS1	ENSG00000184500	0.21994608556940065	[153]	[219,224,223]	3	hSpCas9	negative selection	6049787
93973680	93973703	3	-	27260156	CAL120	viability	CCTAGTGCTTCCCGTCTCAGAGG	PROS1	ENSG00000184500	0.44413559701128497	[626]	[661,1234,1223]	6	hSpCas9	negative selection	6049788
93906047	93906070	3	-	27260156	CAL120	viability	TTTACTTGCACTTGTAAACCAGG	PROS1	ENSG00000184500	0.47967610309582365	[385]	[444,900,629]	7	hSpCas9	negative selection	6049789
93906095	93906118	3	+	27260156	CAL120	viability	ATATATCCATCTTCATTGCATGG	PROS1	ENSG00000184500	0.08828562716901056	[889]	[1251,1117,1172]	1	hSpCas9	negative selection	6114046
93973737	93973760	3	-	27260156	CADOES1	viability	GCGCTTCGAAATGAGGGTCCTGG	PROS1	ENSG00000184500	-0.17576608709299446	[153]	[107,139,113,145]	-3	hSpCas9	negative selection	6171038
93973680	93973703	3	-	27260156	CADOES1	viability	CCTAGTGCTTCCCGTCTCAGAGG	PROS1	ENSG00000184500	-0.0073058451114455525	[626]	[663,648,548,453]	0	hSpCas9	negative selection	6171039
93906047	93906070	3	-	27260156	CADOES1	viability	TTTACTTGCACTTGTAAACCAGG	PROS1	ENSG00000184500	0.3122850784804488	[385]	[422,410,452,497]	5	hSpCas9	negative selection	6171040
93906095	93906118	3	+	27260156	CADOES1	viability	ATATATCCATCTTCATTGCATGG	PROS1	ENSG00000184500	0.14555742840715225	[889]	[797,1116,863,882]	2	hSpCas9	negative selection	6235297
93973737	93973760	3	-	27260156	EWS502	viability	GCGCTTCGAAATGAGGGTCCTGG	PROS1	ENSG00000184500	0.057886605013573345	[153]	[129,173,92,293]	1	hSpCas9	negative selection	6292289
93973680	93973703	3	-	27260156	EWS502	viability	CCTAGTGCTTCCCGTCTCAGAGG	PROS1	ENSG00000184500	0.395257077424011	[626]	[997,833,790,850]	7	hSpCas9	negative selection	6292290
93906047	93906070	3	-	27260156	EWS502	viability	TTTACTTGCACTTGTAAACCAGG	PROS1	ENSG00000184500	0.2602785126367207	[385]	[449,482,484,547]	4	hSpCas9	negative selection	6292291
93906095	93906118	3	+	27260156	EWS502	viability	ATATATCCATCTTCATTGCATGG	PROS1	ENSG00000184500	0.3118757577019976	[889]	[1176,970,1208,1338]	5	hSpCas9	negative selection	6356548
93973737	93973760	3	-	27260156	EW8	viability	GCGCTTCGAAATGAGGGTCCTGG	PROS1	ENSG00000184500	-0.18478458621788807	[153]	[136,98,90,117]	-3	hSpCas9	negative selection	6413540
93973680	93973703	3	-	27260156	EW8	viability	CCTAGTGCTTCCCGTCTCAGAGG	PROS1	ENSG00000184500	0.10116312077968886	[626]	[700,456,451,600]	1	hSpCas9	negative selection	6413541
93906047	93906070	3	-	27260156	EW8	viability	TTTACTTGCACTTGTAAACCAGG	PROS1	ENSG00000184500	0.5057823539515581	[385]	[483,433,406,460]	8	hSpCas9	negative selection	6413542
93906095	93906118	3	+	27260156	EW8	viability	ATATATCCATCTTCATTGCATGG	PROS1	ENSG00000184500	0.16923742503108075	[889]	[1076,789,658,770]	3	hSpCas9	negative selection	6477799
93973737	93973760	3	-	27260156	CORL105	viability	GCGCTTCGAAATGAGGGTCCTGG	PROS1	ENSG00000184500	-0.02956432396139097	[153]	[144,210,215,138]	0	hSpCas9	negative selection	6534791
93973680	93973703	3	-	27260156	CORL105	viability	CCTAGTGCTTCCCGTCTCAGAGG	PROS1	ENSG00000184500	0.5597126602732496	[626]	[1172,922,1098,1140]	8	hSpCas9	negative selection	6534792
93906047	93906070	3	-	27260156	CORL105	viability	TTTACTTGCACTTGTAAACCAGG	PROS1	ENSG00000184500	0.43748223380270446	[385]	[625,678,554,577]	7	hSpCas9	negative selection	6534793
93906095	93906118	3	+	27260156	CORL105	viability	ATATATCCATCTTCATTGCATGG	PROS1	ENSG00000184500	0.11161104214164441	[889]	[1141,933,1562,936]	2	hSpCas9	negative selection	6599050
93973737	93973760	3	-	27260156	HS294T	viability	GCGCTTCGAAATGAGGGTCCTGG	PROS1	ENSG00000184500	-0.35798164307460545	[153]	[46,47,36,54]	-5	hSpCas9	negative selection	6656042
93973680	93973703	3	-	27260156	HS294T	viability	CCTAGTGCTTCCCGTCTCAGAGG	PROS1	ENSG00000184500	0.4753924505479656	[626]	[219,403,355,383]	6	hSpCas9	negative selection	6656043
93906047	93906070	3	-	27260156	HS294T	viability	TTTACTTGCACTTGTAAACCAGG	PROS1	ENSG00000184500	0.815604843422196	[385]	[193,216,329,327]	9	hSpCas9	negative selection	6656044
93906095	93906118	3	+	27260156	HS294T	viability	ATATATCCATCTTCATTGCATGG	PROS1	ENSG00000184500	-0.08754894992328299	[889]	[320,269,288,434]	-1	hSpCas9	negative selection	6720301
93973737	93973760	3	-	27260156	HCC44	viability	GCGCTTCGAAATGAGGGTCCTGG	PROS1	ENSG00000184500	0.3712402901190963	[153]	[339,150,224,204]	6	hSpCas9	negative selection	6777293
93973680	93973703	3	-	27260156	HCC44	viability	CCTAGTGCTTCCCGTCTCAGAGG	PROS1	ENSG00000184500	0.1699747666816009	[626]	[776,882,1006,547]	2	hSpCas9	negative selection	6777294
93906047	93906070	3	-	27260156	HCC44	viability	TTTACTTGCACTTGTAAACCAGG	PROS1	ENSG00000184500	0.7350877468711581	[385]	[719,596,1018,635]	9	hSpCas9	negative selection	6777295
93906095	93906118	3	+	27260156	HCC44	viability	ATATATCCATCTTCATTGCATGG	PROS1	ENSG00000184500	-0.18837042270435056	[889]	[1098,871,889,693]	-3	hSpCas9	negative selection	6841552
93973737	93973760	3	-	27260156	G402	viability	GCGCTTCGAAATGAGGGTCCTGG	PROS1	ENSG00000184500	-0.8708862611414923	[153]	[254,120,46,14]	-8	hSpCas9	negative selection	6898544
93973680	93973703	3	-	27260156	G402	viability	CCTAGTGCTTCCCGTCTCAGAGG	PROS1	ENSG00000184500	-0.15210122676736731	[626]	[963,393,980,446]	-2	hSpCas9	negative selection	6898545
93906047	93906070	3	-	27260156	G402	viability	TTTACTTGCACTTGTAAACCAGG	PROS1	ENSG00000184500	0.20300833233820276	[385]	[825,619,370,401]	2	hSpCas9	negative selection	6898546
93906095	93906118	3	+	27260156	G402	viability	ATATATCCATCTTCATTGCATGG	PROS1	ENSG00000184500	0.3311947535762333	[889]	[1049,1077,2047,1227]	4	hSpCas9	negative selection	6962803
93973737	93973760	3	-	27260156	L33	viability	GCGCTTCGAAATGAGGGTCCTGG	PROS1	ENSG00000184500	0.18249060862834976	[153]	[201,63,171,67]	4	hSpCas9	negative selection	7019795
93973680	93973703	3	-	27260156	L33	viability	CCTAGTGCTTCCCGTCTCAGAGG	PROS1	ENSG00000184500	0.413861236319314	[626]	[780,291,552,967]	8	hSpCas9	negative selection	7019796
93906047	93906070	3	-	27260156	L33	viability	TTTACTTGCACTTGTAAACCAGG	PROS1	ENSG00000184500	0.695947258462789	[385]	[467,273,413,708]	9	hSpCas9	negative selection	7019797
93906095	93906118	3	+	27260156	L33	viability	ATATATCCATCTTCATTGCATGG	PROS1	ENSG00000184500	-0.15819367043255605	[889]	[721,308,459,981]	-4	hSpCas9	negative selection	7084054
93973737	93973760	3	-	27260156	K562	viability	GCGCTTCGAAATGAGGGTCCTGG	PROS1	ENSG00000184500	0.41258924645584116	[153]	[255,51,404,30]	5	hSpCas9	negative selection	7141046
93973680	93973703	3	-	27260156	K562	viability	CCTAGTGCTTCCCGTCTCAGAGG	PROS1	ENSG00000184500	0.7580788316663412	[626]	[847,909,1420,610]	8	hSpCas9	negative selection	7141047
93906047	93906070	3	-	27260156	K562	viability	TTTACTTGCACTTGTAAACCAGG	PROS1	ENSG00000184500	0.2957278614301798	[385]	[551,381,297,452]	3	hSpCas9	negative selection	7141048
93906095	93906118	3	+	27260156	K562	viability	ATATATCCATCTTCATTGCATGG	PROS1	ENSG00000184500	0.08598407208280856	[889]	[1146,931,727,600]	1	hSpCas9	negative selection	7205305
93973737	93973760	3	-	27260156	HT29	viability	GCGCTTCGAAATGAGGGTCCTGG	PROS1	ENSG00000184500	-0.09945295663883069	[153]	[295,90,121,188]	-2	hSpCas9	negative selection	7262297
93973680	93973703	3	-	27260156	HT29	viability	CCTAGTGCTTCCCGTCTCAGAGG	PROS1	ENSG00000184500	0.34267823530525093	[626]	[1078,895,940,947]	6	hSpCas9	negative selection	7262298
93906047	93906070	3	-	27260156	HT29	viability	TTTACTTGCACTTGTAAACCAGG	PROS1	ENSG00000184500	0.24994664801501057	[385]	[566,607,563,500]	5	hSpCas9	negative selection	7262299
93906095	93906118	3	+	27260156	HT29	viability	ATATATCCATCTTCATTGCATGG	PROS1	ENSG00000184500	0.07008377140066324	[889]	[1000,1161,1365,1012]	1	hSpCas9	negative selection	7326556
93973737	93973760	3	-	27260156	MHHES1	viability	GCGCTTCGAAATGAGGGTCCTGG	PROS1	ENSG00000184500	-0.18676838449531563	[153]	[210,154,104,143]	-4	hSpCas9	negative selection	7383548
93973680	93973703	3	-	27260156	MHHES1	viability	CCTAGTGCTTCCCGTCTCAGAGG	PROS1	ENSG00000184500	0.2486385727365797	[626]	[1059,781,729,794]	4	hSpCas9	negative selection	7383549
93906047	93906070	3	-	27260156	MHHES1	viability	TTTACTTGCACTTGTAAACCAGG	PROS1	ENSG00000184500	0.3433380081254598	[385]	[647,638,466,476]	6	hSpCas9	negative selection	7383550
93906095	93906118	3	+	27260156	MHHES1	viability	ATATATCCATCTTCATTGCATGG	PROS1	ENSG00000184500	0.058186445872556725	[889]	[1478,1053,937,791]	1	hSpCas9	negative selection	7447807
93973737	93973760	3	-	27260156	MEWO	viability	GCGCTTCGAAATGAGGGTCCTGG	PROS1	ENSG00000184500	0.1849499579647209	[153]	[228,152,121]	4	hSpCas9	negative selection	7504799
93973680	93973703	3	-	27260156	MEWO	viability	CCTAGTGCTTCCCGTCTCAGAGG	PROS1	ENSG00000184500	0.3694963688893342	[626]	[821,704,758]	7	hSpCas9	negative selection	7504800
93906047	93906070	3	-	27260156	MEWO	viability	TTTACTTGCACTTGTAAACCAGG	PROS1	ENSG00000184500	0.45042930024099537	[385]	[594,481,422]	8	hSpCas9	negative selection	7504801
93906095	93906118	3	+	27260156	MEWO	viability	ATATATCCATCTTCATTGCATGG	PROS1	ENSG00000184500	0.03565873408090281	[889]	[1263,812,562]	0	hSpCas9	negative selection	7569058
93973737	93973760	3	-	27260156	LNCAPCLONEFGC	viability	GCGCTTCGAAATGAGGGTCCTGG	PROS1	ENSG00000184500	0.1959707531447712	[153]	[70,212,204,154]	3	hSpCas9	negative selection	7626050
93973680	93973703	3	-	27260156	LNCAPCLONEFGC	viability	CCTAGTGCTTCCCGTCTCAGAGG	PROS1	ENSG00000184500	0.3299327390047427	[626]	[524,872,549,875]	5	hSpCas9	negative selection	7626051
93906047	93906070	3	-	27260156	LNCAPCLONEFGC	viability	TTTACTTGCACTTGTAAACCAGG	PROS1	ENSG00000184500	0.46148082932931633	[385]	[567,381,518,466]	7	hSpCas9	negative selection	7626052
93906095	93906118	3	+	27260156	LNCAPCLONEFGC	viability	ATATATCCATCTTCATTGCATGG	PROS1	ENSG00000184500	-0.054986819020949484	[889]	[724,972,757,632]	-1	hSpCas9	negative selection	7690309
93973737	93973760	3	-	27260156	PANC0327	viability	GCGCTTCGAAATGAGGGTCCTGG	PROS1	ENSG00000184500	-0.589298324631365	[153]	[88,86,81,105]	-7	hSpCas9	negative selection	7747301
93973680	93973703	3	-	27260156	PANC0327	viability	CCTAGTGCTTCCCGTCTCAGAGG	PROS1	ENSG00000184500	0.68836194620181	[626]	[753,910,786,1123]	8	hSpCas9	negative selection	7747302
93906047	93906070	3	-	27260156	PANC0327	viability	TTTACTTGCACTTGTAAACCAGG	PROS1	ENSG00000184500	0.2997038198045712	[385]	[327,370,471,515]	4	hSpCas9	negative selection	7747303
93906095	93906118	3	+	27260156	PANC0327	viability	ATATATCCATCTTCATTGCATGG	PROS1	ENSG00000184500	0.015778450983557568	[889]	[653,694,1097,751]	0	hSpCas9	negative selection	7811560
93973737	93973760	3	-	27260156	NCIH2009	viability	GCGCTTCGAAATGAGGGTCCTGG	PROS1	ENSG00000184500	0.5412040168639882	[153]	[470,256,242]	7	hSpCas9	negative selection	7868552
93973680	93973703	3	-	27260156	NCIH2009	viability	CCTAGTGCTTCCCGTCTCAGAGG	PROS1	ENSG00000184500	0.4097389794439467	[626]	[1356,967,1205]	5	hSpCas9	negative selection	7868553
93906047	93906070	3	-	27260156	NCIH2009	viability	TTTACTTGCACTTGTAAACCAGG	PROS1	ENSG00000184500	0.9592212791589332	[385]	[1283,959,947]	9	hSpCas9	negative selection	7868554
93906095	93906118	3	+	27260156	NCIH2009	viability	ATATATCCATCTTCATTGCATGG	PROS1	ENSG00000184500	0.09933560935138452	[889]	[1684,1155,1225]	1	hSpCas9	negative selection	7932811
93973737	93973760	3	-	27260156	NCIH1373	viability	GCGCTTCGAAATGAGGGTCCTGG	PROS1	ENSG00000184500	-0.0893551196242357	[153]	[207,69,50,91]	-1	hSpCas9	negative selection	7989803
93973680	93973703	3	-	27260156	NCIH1373	viability	CCTAGTGCTTCCCGTCTCAGAGG	PROS1	ENSG00000184500	0.565526852259977	[626]	[731,763,805,496]	5	hSpCas9	negative selection	7989804
93906047	93906070	3	-	27260156	NCIH1373	viability	TTTACTTGCACTTGTAAACCAGG	PROS1	ENSG00000184500	1.0986973991894042	[385]	[526,816,1284,267]	9	hSpCas9	negative selection	7989805
93906095	93906118	3	+	27260156	NCIH1373	viability	ATATATCCATCTTCATTGCATGG	PROS1	ENSG00000184500	0.08500536559680338	[889]	[1168,1169,996,232]	0	hSpCas9	negative selection	8054062
93973737	93973760	3	-	27260156	PATU8902	viability	GCGCTTCGAAATGAGGGTCCTGG	PROS1	ENSG00000184500	0.7887005880617857	[153]	[505,220,337,426]	8	hSpCas9	negative selection	8111054
93973680	93973703	3	-	27260156	PATU8902	viability	CCTAGTGCTTCCCGTCTCAGAGG	PROS1	ENSG00000184500	0.3759042741918203	[626]	[1288,1259,777,1307]	4	hSpCas9	negative selection	8111055
93906047	93906070	3	-	27260156	PATU8902	viability	TTTACTTGCACTTGTAAACCAGG	PROS1	ENSG00000184500	0.7379902150999949	[385]	[651,1219,690,1097]	7	hSpCas9	negative selection	8111056
93906095	93906118	3	+	27260156	PATU8902	viability	ATATATCCATCTTCATTGCATGG	PROS1	ENSG00000184500	0.3016323663224526	[889]	[878,1794,1674,1746]	3	hSpCas9	negative selection	8175313
93973737	93973760	3	-	27260156	PANC1	viability	GCGCTTCGAAATGAGGGTCCTGG	PROS1	ENSG00000184500	-0.06156545278776604	[153]	[54,287,81,115]	-1	hSpCas9	negative selection	8232305
93973680	93973703	3	-	27260156	PANC1	viability	CCTAGTGCTTCCCGTCTCAGAGG	PROS1	ENSG00000184500	0.32018541773712544	[626]	[776,805,793,376]	5	hSpCas9	negative selection	8232306
93906047	93906070	3	-	27260156	PANC1	viability	TTTACTTGCACTTGTAAACCAGG	PROS1	ENSG00000184500	0.43127855947994254	[385]	[356,601,406,447]	7	hSpCas9	negative selection	8232307
93906095	93906118	3	+	27260156	PANC1	viability	ATATATCCATCTTCATTGCATGG	PROS1	ENSG00000184500	0.16348735158228178	[889]	[718,717,1081,865]	2	hSpCas9	negative selection	8296564
93973737	93973760	3	-	27260156	PANC0813	viability	GCGCTTCGAAATGAGGGTCCTGG	PROS1	ENSG00000184500	0.3879145864707154	[153]	[205,220,317,200]	6	hSpCas9	negative selection	8353556
93973680	93973703	3	-	27260156	PANC0813	viability	CCTAGTGCTTCCCGTCTCAGAGG	PROS1	ENSG00000184500	0.2604558047575774	[626]	[757,1013,882,861]	4	hSpCas9	negative selection	8353557
93906047	93906070	3	-	27260156	PANC0813	viability	TTTACTTGCACTTGTAAACCAGG	PROS1	ENSG00000184500	0.8249919225273649	[385]	[724,954,705,816]	9	hSpCas9	negative selection	8353558
93906095	93906118	3	+	27260156	PANC0813	viability	ATATATCCATCTTCATTGCATGG	PROS1	ENSG00000184500	-0.10377420584823016	[889]	[1022,944,1031,898]	-2	hSpCas9	negative selection	8417815
93973737	93973760	3	-	27260156	RDES	viability	GCGCTTCGAAATGAGGGTCCTGG	PROS1	ENSG00000184500	-0.11464372890680674	[153]	[196,148,144,147]	-2	hSpCas9	negative selection	8474807
93973680	93973703	3	-	27260156	RDES	viability	CCTAGTGCTTCCCGTCTCAGAGG	PROS1	ENSG00000184500	0.20688596396458753	[626]	[816,678,810,1043]	3	hSpCas9	negative selection	8474808
93906047	93906070	3	-	27260156	RDES	viability	TTTACTTGCACTTGTAAACCAGG	PROS1	ENSG00000184500	0.5469869268279764	[385]	[514,783,634,655]	8	hSpCas9	negative selection	8474809
93906095	93906118	3	+	27260156	RDES	viability	ATATATCCATCTTCATTGCATGG	PROS1	ENSG00000184500	0.09630676272641236	[889]	[974,1063,1223,1114]	1	hSpCas9	negative selection	8539066
93973737	93973760	3	-	27260156	PC3	viability	GCGCTTCGAAATGAGGGTCCTGG	PROS1	ENSG00000184500	-0.310003516135682	[153]	[51,167,163,147]	-6	hSpCas9	negative selection	8596058
93973680	93973703	3	-	27260156	PC3	viability	CCTAGTGCTTCCCGTCTCAGAGG	PROS1	ENSG00000184500	0.34772313417180317	[626]	[437,715,1347,995]	7	hSpCas9	negative selection	8596059
93906047	93906070	3	-	27260156	PC3	viability	TTTACTTGCACTTGTAAACCAGG	PROS1	ENSG00000184500	0.1936676611979079	[385]	[387,475,466,398]	4	hSpCas9	negative selection	8596060
93906095	93906118	3	+	27260156	PC3	viability	ATATATCCATCTTCATTGCATGG	PROS1	ENSG00000184500	0.07856403455353966	[889]	[569,939,1455,1059]	1	hSpCas9	negative selection	8660317
93973737	93973760	3	-	27260156	PATU8988T	viability	GCGCTTCGAAATGAGGGTCCTGG	PROS1	ENSG00000184500	-0.8414591020197377	[153]	[50,105,85,91]	-8	hSpCas9	negative selection	8717309
93973680	93973703	3	-	27260156	PATU8988T	viability	CCTAGTGCTTCCCGTCTCAGAGG	PROS1	ENSG00000184500	0.21047631758360358	[626]	[522,666,710,916]	3	hSpCas9	negative selection	8717310
93906047	93906070	3	-	27260156	PATU8988T	viability	TTTACTTGCACTTGTAAACCAGG	PROS1	ENSG00000184500	0.27083114624669724	[385]	[544,451,417,379]	4	hSpCas9	negative selection	8717311
93906095	93906118	3	+	27260156	PATU8988T	viability	ATATATCCATCTTCATTGCATGG	PROS1	ENSG00000184500	-0.15296020492340578	[889]	[740,731,685,945]	-3	hSpCas9	negative selection	8781568
93973737	93973760	3	-	27260156	T47D	viability	GCGCTTCGAAATGAGGGTCCTGG	PROS1	ENSG00000184500	0.07226683153684865	[153]	[248,158,154,194]	1	hSpCas9	negative selection	8838560
93973680	93973703	3	-	27260156	T47D	viability	CCTAGTGCTTCCCGTCTCAGAGG	PROS1	ENSG00000184500	0.21922920541633623	[626]	[743,739,902,1027]	4	hSpCas9	negative selection	8838561
93906047	93906070	3	-	27260156	T47D	viability	TTTACTTGCACTTGTAAACCAGG	PROS1	ENSG00000184500	0.26241811196117476	[385]	[484,545,561,563]	5	hSpCas9	negative selection	8838562
93906095	93906118	3	+	27260156	T47D	viability	ATATATCCATCTTCATTGCATGG	PROS1	ENSG00000184500	0.2238015498028586	[889]	[1199,1150,1099,1404]	5	hSpCas9	negative selection	8902819
93973737	93973760	3	-	27260156	SU8686	viability	GCGCTTCGAAATGAGGGTCCTGG	PROS1	ENSG00000184500	0.0704467226432326	[153]	[168,123,176,176]	1	hSpCas9	negative selection	8959811
93973680	93973703	3	-	27260156	SU8686	viability	CCTAGTGCTTCCCGTCTCAGAGG	PROS1	ENSG00000184500	-0.024758274059345997	[626]	[546,719,509,660]	0	hSpCas9	negative selection	8959812
93906047	93906070	3	-	27260156	SU8686	viability	TTTACTTGCACTTGTAAACCAGG	PROS1	ENSG00000184500	0.541358728582094	[385]	[500,452,554,768]	8	hSpCas9	negative selection	8959813
93906095	93906118	3	+	27260156	SU8686	viability	ATATATCCATCTTCATTGCATGG	PROS1	ENSG00000184500	-0.14244242131734297	[889]	[881,752,807,734]	-3	hSpCas9	negative selection	9024070
93973737	93973760	3	-	27260156	SKES1	viability	GCGCTTCGAAATGAGGGTCCTGG	PROS1	ENSG00000184500	0.1168726201040795	[153]	[182,193,140,153]	2	hSpCas9	negative selection	9081062
93973680	93973703	3	-	27260156	SKES1	viability	CCTAGTGCTTCCCGTCTCAGAGG	PROS1	ENSG00000184500	0.391468689655394	[626]	[831,966,797,708]	7	hSpCas9	negative selection	9081063
93906047	93906070	3	-	27260156	SKES1	viability	TTTACTTGCACTTGTAAACCAGG	PROS1	ENSG00000184500	0.47519507288747365	[385]	[591,586,407,560]	8	hSpCas9	negative selection	9081064
93906095	93906118	3	+	27260156	SKES1	viability	ATATATCCATCTTCATTGCATGG	PROS1	ENSG00000184500	0.033581502378353	[889]	[963,984,851,848]	0	hSpCas9	negative selection	9145321
93973737	93973760	3	-	27260156	TOV112D	viability	GCGCTTCGAAATGAGGGTCCTGG	PROS1	ENSG00000184500	-0.4007799469920761	[153]	[148,209,61,72]	-7	hSpCas9	negative selection	9202313
93973680	93973703	3	-	27260156	TOV112D	viability	CCTAGTGCTTCCCGTCTCAGAGG	PROS1	ENSG00000184500	0.20293789844298277	[626]	[1117,887,560,405]	4	hSpCas9	negative selection	9202314
93906047	93906070	3	-	27260156	TOV112D	viability	TTTACTTGCACTTGTAAACCAGG	PROS1	ENSG00000184500	0.0010096831106256587	[385]	[442,533,340,272]	0	hSpCas9	negative selection	9202315
93906095	93906118	3	+	27260156	TOV112D	viability	ATATATCCATCTTCATTGCATGG	PROS1	ENSG00000184500	0.12246989007286235	[889]	[964,1308,801,888]	2	hSpCas9	negative selection	9266572
93973737	93973760	3	-	27260156	TC71	viability	GCGCTTCGAAATGAGGGTCCTGG	PROS1	ENSG00000184500	0.03996958612786994	[153]	[114,184,186,193]	1	hSpCas9	negative selection	9323564
93973680	93973703	3	-	27260156	TC71	viability	CCTAGTGCTTCCCGTCTCAGAGG	PROS1	ENSG00000184500	-0.03982573230177677	[626]	[677,627,610,701]	-1	hSpCas9	negative selection	9323565
93906047	93906070	3	-	27260156	TC71	viability	TTTACTTGCACTTGTAAACCAGG	PROS1	ENSG00000184500	0.2827003922230766	[385]	[389,584,523,516]	7	hSpCas9	negative selection	9323566
93906095	93906118	3	+	27260156	TC71	viability	ATATATCCATCTTCATTGCATGG	PROS1	ENSG00000184500	0.2321249399707107	[889]	[1145,1235,894,1217]	6	hSpCas9	negative selection	9387823
93973737	93973760	3	-	27260156	TC32	viability	GCGCTTCGAAATGAGGGTCCTGG	PROS1	ENSG00000184500	0.21495912694907537	[153]	[149,184,164,154]	4	hSpCas9	negative selection	9444815
93973680	93973703	3	-	27260156	TC32	viability	CCTAGTGCTTCCCGTCTCAGAGG	PROS1	ENSG00000184500	-0.13280132754659174	[626]	[528,445,571,614]	-2	hSpCas9	negative selection	9444816
93906047	93906070	3	-	27260156	TC32	viability	TTTACTTGCACTTGTAAACCAGG	PROS1	ENSG00000184500	0.2319249412809673	[385]	[300,326,648,498]	4	hSpCas9	negative selection	9444817
93906095	93906118	3	+	27260156	TC32	viability	ATATATCCATCTTCATTGCATGG	PROS1	ENSG00000184500	0.16077519116297767	[889]	[710,717,1150,1272]	3	hSpCas9	negative selection	9509074
93884868	93884891	3	+	27869803	HPAFII	viability after 27 days	CGTATACATCCATCTAGACGAGG	PROS1	ENSG00000184500	-0.34610564533688226	[654]	[271,269,NaN]	-3	hSpCas9	negative selection	9586218
93884868	93884891	3	+	27869803	HPAFII	viability after 15 days	CGTATACATCCATCTAGACGAGG	PROS1	ENSG00000184500	-0.34467710985402555	[654]	[533,566,NaN]	-4	hSpCas9	negative selection	9668667
93884868	93884891	3	+	27869803	ASPC1	viability after 36 days	CGTATACATCCATCTAGACGAGG	PROS1	ENSG00000184500	0.19304461863992195	[1419]	[444,669,563]	2	hSpCas9	negative selection	9751116
93884868	93884891	3	+	27869803	PATU8988S	viability after 35 days	CGTATACATCCATCTAGACGAGG	PROS1	ENSG00000184500	0.497484111905657	[1485]	[806,882,NaN]	5	hSpCas9	negative selection	9833565
93884868	93884891	3	+	27869803	PATU8988S	viability after 31 days	CGTATACATCCATCTAGACGAGG	PROS1	ENSG00000184500	0.2370301879608423	[1485]	[590,834,NaN]	3	hSpCas9	negative selection	9916014
93884868	93884891	3	+	27869803	HPAFII	viability after 35 days	CGTATACATCCATCTAGACGAGG	PROS1	ENSG00000184500	0.018834235767061225	[654]	[231,452,NaN]	0	hSpCas9	negative selection	9998463
93884868	93884891	3	+	27869803	HPAFII	viability after 31 days	CGTATACATCCATCTAGACGAGG	PROS1	ENSG00000184500	-0.20382448306362888	[654]	[266,375,NaN]	-1	hSpCas9	negative selection	10080912
93927276	93927299	3	-	28162770	P31FUJ	viability	GTGCAATAAAGAAGAAGCCAGGG	PROS1	ENSG00000184500	0.07205237711404222	[118]	[146]	0	hSpCas9	negative selection	10217539
93886347	93886370	3	+	28162770	P31FUJ	viability	GTTCACTTTCCACTTTCCGAGGG	PROS1	ENSG00000184500	0.01912974785100574	[586]	[698]	0	hSpCas9	negative selection	10217540
93927255	93927278	3	-	28162770	P31FUJ	viability	GGAGGTCTTTGAAAATGACCCGG	PROS1	ENSG00000184500	0.6633619846010814	[35]	[66]	7	hSpCas9	negative selection	10217541
93884869	93884892	3	+	28162770	P31FUJ	viability	GTATACATCCATCTAGACGAGGG	PROS1	ENSG00000184500	1.0249955530532682	[45]	[109]	9	hSpCas9	negative selection	10217542
93876974	93876997	3	-	28162770	P31FUJ	viability	AAAGTGGCCACATACCTGGGTGG	PROS1	ENSG00000184500	0.665467908621795	[234]	[437]	7	hSpCas9	negative selection	10217543
93973724	93973747	3	-	28162770	P31FUJ	viability	AGGGTCCTGGGTGGGCGCTGCGG	PROS1	ENSG00000184500	0.945535036844134	[18]	[42]	9	hSpCas9	negative selection	10217544
93927375	93927398	3	-	28162770	P31FUJ	viability	GCAACAGGCTTCACAAGTCCTGG	PROS1	ENSG00000184500	0.6106400178811381	[281]	[505]	7	hSpCas9	negative selection	10217545
93879235	93879258	3	+	28162770	P31FUJ	viability	AAGCATAACACCAGTGCCCGTGG	PROS1	ENSG00000184500	0.2328613679344333	[230]	[318]	2	hSpCas9	negative selection	10217546
93896616	93896639	3	-	28162770	P31FUJ	viability	CTTGGCGGAGCAGTTTGCAGGGG	PROS1	ENSG00000184500	0.3125040959549872	[626]	[914]	3	hSpCas9	negative selection	10217547
93893041	93893064	3	-	28162770	P31FUJ	viability	AATCTATCGATCACTCAGCGTGG	PROS1	ENSG00000184500	0.849074802640029	[136]	[289]	8	hSpCas9	negative selection	10217548
93927276	93927299	3	-	28162770	TF1	viability	GTGCAATAAAGAAGAAGCCAGGG	PROS1	ENSG00000184500	NaN	[NaN]	[257]	1	hSpCas9	negative selection	10386905
93886347	93886370	3	+	28162770	TF1	viability	GTTCACTTTCCACTTTCCGAGGG	PROS1	ENSG00000184500	NaN	[NaN]	[482]	1	hSpCas9	negative selection	10386906
93927255	93927278	3	-	28162770	TF1	viability	GGAGGTCTTTGAAAATGACCCGG	PROS1	ENSG00000184500	NaN	[NaN]	[79]	1	hSpCas9	negative selection	10386907
93884869	93884892	3	+	28162770	TF1	viability	GTATACATCCATCTAGACGAGGG	PROS1	ENSG00000184500	NaN	[NaN]	[28]	1	hSpCas9	negative selection	10386908
93876974	93876997	3	-	28162770	TF1	viability	AAAGTGGCCACATACCTGGGTGG	PROS1	ENSG00000184500	NaN	[NaN]	[332]	1	hSpCas9	negative selection	10386909
93973724	93973747	3	-	28162770	TF1	viability	AGGGTCCTGGGTGGGCGCTGCGG	PROS1	ENSG00000184500	NaN	[NaN]	[10]	1	hSpCas9	negative selection	10386910
93927375	93927398	3	-	28162770	TF1	viability	GCAACAGGCTTCACAAGTCCTGG	PROS1	ENSG00000184500	NaN	[NaN]	[321]	1	hSpCas9	negative selection	10386911
93879235	93879258	3	+	28162770	TF1	viability	AAGCATAACACCAGTGCCCGTGG	PROS1	ENSG00000184500	NaN	[NaN]	[234]	1	hSpCas9	negative selection	10386912
93896616	93896639	3	-	28162770	TF1	viability	CTTGGCGGAGCAGTTTGCAGGGG	PROS1	ENSG00000184500	NaN	[NaN]	[505]	1	hSpCas9	negative selection	10386913
93893041	93893064	3	-	28162770	TF1	viability	AATCTATCGATCACTCAGCGTGG	PROS1	ENSG00000184500	NaN	[NaN]	[173]	1	hSpCas9	negative selection	10386914
93927276	93927299	3	-	28162770	SKM1	viability	GTGCAATAAAGAAGAAGCCAGGG	PROS1	ENSG00000184500	0.7393095346345055	[40]	[120]	7	hSpCas9	negative selection	10556271
93886347	93886370	3	+	28162770	SKM1	viability	GTTCACTTTCCACTTTCCGAGGG	PROS1	ENSG00000184500	0.25600081397926777	[107]	[227]	2	hSpCas9	negative selection	10556272
93927255	93927278	3	-	28162770	SKM1	viability	GGAGGTCTTTGAAAATGACCCGG	PROS1	ENSG00000184500	0.24212863939771	[21]	[45]	2	hSpCas9	negative selection	10556273
93884869	93884892	3	+	28162770	SKM1	viability	GTATACATCCATCTAGACGAGGG	PROS1	ENSG00000184500	0.9435330483409714	[9]	[33]	8	hSpCas9	negative selection	10556274
93876974	93876997	3	-	28162770	SKM1	viability	AAAGTGGCCACATACCTGGGTGG	PROS1	ENSG00000184500	1.156936686450165	[68]	[271]	9	hSpCas9	negative selection	10556275
93973724	93973747	3	-	28162770	SKM1	viability	AGGGTCCTGGGTGGGCGCTGCGG	PROS1	ENSG00000184500	-0.5996092766855576	[5]	[6]	-5	hSpCas9	negative selection	10556276
93927375	93927398	3	-	28162770	SKM1	viability	GCAACAGGCTTCACAAGTCCTGG	PROS1	ENSG00000184500	0.8112159713063716	[48]	[151]	7	hSpCas9	negative selection	10556277
93879235	93879258	3	+	28162770	SKM1	viability	AAGCATAACACCAGTGCCCGTGG	PROS1	ENSG00000184500	-0.8785852263883729	[77]	[74]	-6	hSpCas9	negative selection	10556278
93896616	93896639	3	-	28162770	SKM1	viability	CTTGGCGGAGCAGTTTGCAGGGG	PROS1	ENSG00000184500	0.484886997401216	[134]	[333]	5	hSpCas9	negative selection	10556279
93893041	93893064	3	-	28162770	SKM1	viability	AATCTATCGATCACTCAGCGTGG	PROS1	ENSG00000184500	1.14019626926561	[28]	[112]	9	hSpCas9	negative selection	10556280
93927276	93927299	3	-	28162770	SKM1	viability	GTGCAATAAAGAAGAAGCCAGGG	PROS1	ENSG00000184500	0.7393095346345055	[40]	[120]	7	hSpCas9	negative selection	10725637
93886347	93886370	3	+	28162770	SKM1	viability	GTTCACTTTCCACTTTCCGAGGG	PROS1	ENSG00000184500	0.25600081397926777	[107]	[227]	2	hSpCas9	negative selection	10725638
93927255	93927278	3	-	28162770	SKM1	viability	GGAGGTCTTTGAAAATGACCCGG	PROS1	ENSG00000184500	0.24212863939771	[21]	[45]	2	hSpCas9	negative selection	10725639
93884869	93884892	3	+	28162770	SKM1	viability	GTATACATCCATCTAGACGAGGG	PROS1	ENSG00000184500	0.9435330483409714	[9]	[33]	8	hSpCas9	negative selection	10725640
93876974	93876997	3	-	28162770	SKM1	viability	AAAGTGGCCACATACCTGGGTGG	PROS1	ENSG00000184500	1.156936686450165	[68]	[271]	9	hSpCas9	negative selection	10725641
93973724	93973747	3	-	28162770	SKM1	viability	AGGGTCCTGGGTGGGCGCTGCGG	PROS1	ENSG00000184500	-0.5996092766855576	[5]	[6]	-5	hSpCas9	negative selection	10725642
93927375	93927398	3	-	28162770	SKM1	viability	GCAACAGGCTTCACAAGTCCTGG	PROS1	ENSG00000184500	0.8112159713063716	[48]	[151]	7	hSpCas9	negative selection	10725643
93879235	93879258	3	+	28162770	SKM1	viability	AAGCATAACACCAGTGCCCGTGG	PROS1	ENSG00000184500	-0.8785852263883729	[77]	[74]	-6	hSpCas9	negative selection	10725644
93896616	93896639	3	-	28162770	SKM1	viability	CTTGGCGGAGCAGTTTGCAGGGG	PROS1	ENSG00000184500	0.484886997401216	[134]	[333]	5	hSpCas9	negative selection	10725645
93893041	93893064	3	-	28162770	SKM1	viability	AATCTATCGATCACTCAGCGTGG	PROS1	ENSG00000184500	1.14019626926561	[28]	[112]	9	hSpCas9	negative selection	10725646
93927276	93927299	3	-	28162770	PL21	viability	GTGCAATAAAGAAGAAGCCAGGG	PROS1	ENSG00000184500	-0.08766269649341596	[187]	[76]	0	hSpCas9	negative selection	10895003
93886347	93886370	3	+	28162770	PL21	viability	GTTCACTTTCCACTTTCCGAGGG	PROS1	ENSG00000184500	0.665262345204473	[367]	[253]	6	hSpCas9	negative selection	10895004
93927255	93927278	3	-	28162770	PL21	viability	GGAGGTCTTTGAAAATGACCCGG	PROS1	ENSG00000184500	-0.3605753399851588	[58]	[19]	-3	hSpCas9	negative selection	10895005
93884869	93884892	3	+	28162770	PL21	viability	GTATACATCCATCTAGACGAGGG	PROS1	ENSG00000184500	-0.6208902444653601	[52]	[14]	-4	hSpCas9	negative selection	10895006
93876974	93876997	3	-	28162770	PL21	viability	AAAGTGGCCACATACCTGGGTGG	PROS1	ENSG00000184500	0.6200428689399802	[295]	[197]	5	hSpCas9	negative selection	10895007
93973724	93973747	3	-	28162770	PL21	viability	AGGGTCCTGGGTGGGCGCTGCGG	PROS1	ENSG00000184500	-0.18688350861992697	[33]	[12]	-1	hSpCas9	negative selection	10895008
93927375	93927398	3	-	28162770	PL21	viability	GCAACAGGCTTCACAAGTCCTGG	PROS1	ENSG00000184500	1.428032214202857	[186]	[218]	9	hSpCas9	negative selection	10895009
93879235	93879258	3	+	28162770	PL21	viability	AAGCATAACACCAGTGCCCGTGG	PROS1	ENSG00000184500	0.01571504335189272	[149]	[65]	0	hSpCas9	negative selection	10895010
93896616	93896639	3	-	28162770	PL21	viability	CTTGGCGGAGCAGTTTGCAGGGG	PROS1	ENSG00000184500	-0.4735000443080567	[519]	[162]	-3	hSpCas9	negative selection	10895011
93893041	93893064	3	-	28162770	PL21	viability	AATCTATCGATCACTCAGCGTGG	PROS1	ENSG00000184500	0.4205296829146203	[102]	[59]	3	hSpCas9	negative selection	10895012
93927276	93927299	3	-	28162770	P31FUJ	viability	GTGCAATAAAGAAGAAGCCAGGG	PROS1	ENSG00000184500	0.07205237711404222	[118]	[146]	0	hSpCas9	negative selection	11064369
93886347	93886370	3	+	28162770	P31FUJ	viability	GTTCACTTTCCACTTTCCGAGGG	PROS1	ENSG00000184500	0.01912974785100574	[586]	[698]	0	hSpCas9	negative selection	11064370
93927255	93927278	3	-	28162770	P31FUJ	viability	GGAGGTCTTTGAAAATGACCCGG	PROS1	ENSG00000184500	0.6633619846010814	[35]	[66]	7	hSpCas9	negative selection	11064371
93884869	93884892	3	+	28162770	P31FUJ	viability	GTATACATCCATCTAGACGAGGG	PROS1	ENSG00000184500	1.0249955530532682	[45]	[109]	9	hSpCas9	negative selection	11064372
93876974	93876997	3	-	28162770	P31FUJ	viability	AAAGTGGCCACATACCTGGGTGG	PROS1	ENSG00000184500	0.665467908621795	[234]	[437]	7	hSpCas9	negative selection	11064373
93973724	93973747	3	-	28162770	P31FUJ	viability	AGGGTCCTGGGTGGGCGCTGCGG	PROS1	ENSG00000184500	0.945535036844134	[18]	[42]	9	hSpCas9	negative selection	11064374
93927375	93927398	3	-	28162770	P31FUJ	viability	GCAACAGGCTTCACAAGTCCTGG	PROS1	ENSG00000184500	0.6106400178811381	[281]	[505]	7	hSpCas9	negative selection	11064375
93879235	93879258	3	+	28162770	P31FUJ	viability	AAGCATAACACCAGTGCCCGTGG	PROS1	ENSG00000184500	0.2328613679344333	[230]	[318]	2	hSpCas9	negative selection	11064376
93896616	93896639	3	-	28162770	P31FUJ	viability	CTTGGCGGAGCAGTTTGCAGGGG	PROS1	ENSG00000184500	0.3125040959549872	[626]	[914]	3	hSpCas9	negative selection	11064377
93893041	93893064	3	-	28162770	P31FUJ	viability	AATCTATCGATCACTCAGCGTGG	PROS1	ENSG00000184500	0.849074802640029	[136]	[289]	8	hSpCas9	negative selection	11064378
93927276	93927299	3	-	28162770	OCIAML5	viability	GTGCAATAAAGAAGAAGCCAGGG	PROS1	ENSG00000184500	-0.022796872377952207	[111]	[198]	0	hSpCas9	negative selection	11233735
93886347	93886370	3	+	28162770	OCIAML5	viability	GTTCACTTTCCACTTTCCGAGGG	PROS1	ENSG00000184500	0.2803837251596526	[259]	[569]	2	hSpCas9	negative selection	11233736
93927255	93927278	3	-	28162770	OCIAML5	viability	GGAGGTCTTTGAAAATGACCCGG	PROS1	ENSG00000184500	0.9929587691596624	[26]	[96]	8	hSpCas9	negative selection	11233737
93884869	93884892	3	+	28162770	OCIAML5	viability	GTATACATCCATCTAGACGAGGG	PROS1	ENSG00000184500	-0.23315673821950345	[27]	[42]	-2	hSpCas9	negative selection	11233738
93876974	93876997	3	-	28162770	OCIAML5	viability	AAAGTGGCCACATACCTGGGTGG	PROS1	ENSG00000184500	0.6757520227535503	[102]	[296]	6	hSpCas9	negative selection	11233739
93973724	93973747	3	-	28162770	OCIAML5	viability	AGGGTCCTGGGTGGGCGCTGCGG	PROS1	ENSG00000184500	-2.617601317226974	[16]	[4]	-8	hSpCas9	negative selection	11233740
93927375	93927398	3	-	28162770	OCIAML5	viability	GCAACAGGCTTCACAAGTCCTGG	PROS1	ENSG00000184500	0.5616245027073302	[133]	[356]	5	hSpCas9	negative selection	11233741
93879235	93879258	3	+	28162770	OCIAML5	viability	AAGCATAACACCAGTGCCCGTGG	PROS1	ENSG00000184500	0.5917681927222818	[92]	[252]	5	hSpCas9	negative selection	11233742
93896616	93896639	3	-	28162770	OCIAML5	viability	CTTGGCGGAGCAGTTTGCAGGGG	PROS1	ENSG00000184500	0.437230519783399	[312]	[764]	4	hSpCas9	negative selection	11233743
93893041	93893064	3	-	28162770	OCIAML5	viability	AATCTATCGATCACTCAGCGTGG	PROS1	ENSG00000184500	0.4447080467950273	[80]	[198]	4	hSpCas9	negative selection	11233744
93927276	93927299	3	-	28162770	EOL1	viability	GTGCAATAAAGAAGAAGCCAGGG	PROS1	ENSG00000184500	-0.6328288974787222	[258]	[87]	-4	hSpCas9	negative selection	11403101
93886347	93886370	3	+	28162770	EOL1	viability	GTTCACTTTCCACTTTCCGAGGG	PROS1	ENSG00000184500	-0.6658691592427297	[529]	[175]	-5	hSpCas9	negative selection	11403102
93927255	93927278	3	-	28162770	EOL1	viability	GGAGGTCTTTGAAAATGACCCGG	PROS1	ENSG00000184500	0.5676132268552588	[145]	[113]	5	hSpCas9	negative selection	11403103
93884869	93884892	3	+	28162770	EOL1	viability	GTATACATCCATCTAGACGAGGG	PROS1	ENSG00000184500	-0.251302063828883	[60]	[26]	-2	hSpCas9	negative selection	11403104
93876974	93876997	3	-	28162770	EOL1	viability	AAAGTGGCCACATACCTGGGTGG	PROS1	ENSG00000184500	0.018875154118687787	[443]	[236]	0	hSpCas9	negative selection	11403105
93973724	93973747	3	-	28162770	EOL1	viability	AGGGTCCTGGGTGGGCGCTGCGG	PROS1	ENSG00000184500	0.7381346473396531	[32]	[28]	6	hSpCas9	negative selection	11403106
93927375	93927398	3	-	28162770	EOL1	viability	GCAACAGGCTTCACAAGTCCTGG	PROS1	ENSG00000184500	-0.8058451686721853	[218]	[65]	-5	hSpCas9	negative selection	11403107
93879235	93879258	3	+	28162770	EOL1	viability	AAGCATAACACCAGTGCCCGTGG	PROS1	ENSG00000184500	-1.119846347787919	[263]	[63]	-6	hSpCas9	negative selection	11403108
93896616	93896639	3	-	28162770	EOL1	viability	CTTGGCGGAGCAGTTTGCAGGGG	PROS1	ENSG00000184500	-0.2640761089250174	[562]	[246]	-2	hSpCas9	negative selection	11403109
93893041	93893064	3	-	28162770	EOL1	viability	AATCTATCGATCACTCAGCGTGG	PROS1	ENSG00000184500	0.3395852708493782	[131]	[87]	3	hSpCas9	negative selection	11403110
93927276	93927299	3	-	28162770	MOLM13	viability	GTGCAATAAAGAAGAAGCCAGGG	PROS1	ENSG00000184500	-0.11707311917657748	[236]	[157]	0	hSpCas9	negative selection	11572467
93886347	93886370	3	+	28162770	MOLM13	viability	GTTCACTTTCCACTTTCCGAGGG	PROS1	ENSG00000184500	0.17042756556966876	[686]	[558]	1	hSpCas9	negative selection	11572468
93927255	93927278	3	-	28162770	MOLM13	viability	GGAGGTCTTTGAAAATGACCCGG	PROS1	ENSG00000184500	0.7031058432386101	[95]	[112]	5	hSpCas9	negative selection	11572469
93884869	93884892	3	+	28162770	MOLM13	viability	GTATACATCCATCTAGACGAGGG	PROS1	ENSG00000184500	1.4579739126794962	[72]	[144]	9	hSpCas9	negative selection	11572470
93876974	93876997	3	-	28162770	MOLM13	viability	AAAGTGGCCACATACCTGGGTGG	PROS1	ENSG00000184500	0.4102507556766346	[382]	[367]	3	hSpCas9	negative selection	11572471
93973724	93973747	3	-	28162770	MOLM13	viability	AGGGTCCTGGGTGGGCGCTGCGG	PROS1	ENSG00000184500	-0.006041806787833615	[24]	[17]	0	hSpCas9	negative selection	11572472
93927375	93927398	3	-	28162770	MOLM13	viability	GCAACAGGCTTCACAAGTCCTGG	PROS1	ENSG00000184500	0.17382808009016049	[281]	[229]	1	hSpCas9	negative selection	11572473
93879235	93879258	3	+	28162770	MOLM13	viability	AAGCATAACACCAGTGCCCGTGG	PROS1	ENSG00000184500	0.05657496830845245	[257]	[193]	0	hSpCas9	negative selection	11572474
93896616	93896639	3	-	28162770	MOLM13	viability	CTTGGCGGAGCAGTTTGCAGGGG	PROS1	ENSG00000184500	0.11214906594950702	[571]	[446]	0	hSpCas9	negative selection	11572475
93893041	93893064	3	-	28162770	MOLM13	viability	AATCTATCGATCACTCAGCGTGG	PROS1	ENSG00000184500	0.8103787989142577	[208]	[264]	6	hSpCas9	negative selection	11572476
93927276	93927299	3	-	28162770	HEL	viability	GTGCAATAAAGAAGAAGCCAGGG	PROS1	ENSG00000184500	0.5951208117676172	[153]	[148]	5	hSpCas9	negative selection	11741833
93886347	93886370	3	+	28162770	HEL	viability	GTTCACTTTCCACTTTCCGAGGG	PROS1	ENSG00000184500	0.032539039780177914	[518]	[339]	0	hSpCas9	negative selection	11741834
93927255	93927278	3	-	28162770	HEL	viability	GGAGGTCTTTGAAAATGACCCGG	PROS1	ENSG00000184500	-0.009337864579336275	[109]	[69]	0	hSpCas9	negative selection	11741835
93884869	93884892	3	+	28162770	HEL	viability	GTATACATCCATCTAGACGAGGG	PROS1	ENSG00000184500	-0.7397308048220561	[72]	[27]	-5	hSpCas9	negative selection	11741836
93876974	93876997	3	-	28162770	HEL	viability	AAAGTGGCCACATACCTGGGTGG	PROS1	ENSG00000184500	0.5292098863699426	[369]	[341]	4	hSpCas9	negative selection	11741837
93973724	93973747	3	-	28162770	HEL	viability	AGGGTCCTGGGTGGGCGCTGCGG	PROS1	ENSG00000184500	2.6871329513588105	[15]	[65]	9	hSpCas9	negative selection	11741838
93927375	93927398	3	-	28162770	HEL	viability	GCAACAGGCTTCACAAGTCCTGG	PROS1	ENSG00000184500	-0.6680487052818048	[257]	[103]	-4	hSpCas9	negative selection	11741839
93879235	93879258	3	+	28162770	HEL	viability	AAGCATAACACCAGTGCCCGTGG	PROS1	ENSG00000184500	-0.003952658472505477	[190]	[121]	0	hSpCas9	negative selection	11741840
93896616	93896639	3	-	28162770	HEL	viability	CTTGGCGGAGCAGTTTGCAGGGG	PROS1	ENSG00000184500	0.08466402053401212	[504]	[342]	0	hSpCas9	negative selection	11741841
93893041	93893064	3	-	28162770	HEL	viability	AATCTATCGATCACTCAGCGTGG	PROS1	ENSG00000184500	-0.4649018911876128	[152]	[70]	-3	hSpCas9	negative selection	11741842
93927276	93927299	3	-	28162770	MV411	viability	GTGCAATAAAGAAGAAGCCAGGG	PROS1	ENSG00000184500	-0.138055672882053	[144]	[110]	-1	hSpCas9	negative selection	11911199
93886347	93886370	3	+	28162770	MV411	viability	GTTCACTTTCCACTTTCCGAGGG	PROS1	ENSG00000184500	0.4846269740473037	[290]	[342]	4	hSpCas9	negative selection	11911200
93927255	93927278	3	-	28162770	MV411	viability	GGAGGTCTTTGAAAATGACCCGG	PROS1	ENSG00000184500	0.2859116985974106	[36]	[37]	2	hSpCas9	negative selection	11911201
93884869	93884892	3	+	28162770	MV411	viability	GTATACATCCATCTAGACGAGGG	PROS1	ENSG00000184500	1.0823783045122788	[36]	[65]	8	hSpCas9	negative selection	11911202
93876974	93876997	3	-	28162770	MV411	viability	AAAGTGGCCACATACCTGGGTGG	PROS1	ENSG00000184500	0.8859294479207266	[193]	[301]	7	hSpCas9	negative selection	11911203
93973724	93973747	3	-	28162770	MV411	viability	AGGGTCCTGGGTGGGCGCTGCGG	PROS1	ENSG00000184500	1.5693656456701377	[15]	[39]	9	hSpCas9	negative selection	11911204
93927375	93927398	3	-	28162770	MV411	viability	GCAACAGGCTTCACAAGTCCTGG	PROS1	ENSG00000184500	0.7147695575038321	[148]	[205]	6	hSpCas9	negative selection	11911205
93879235	93879258	3	+	28162770	MV411	viability	AAGCATAACACCAGTGCCCGTGG	PROS1	ENSG00000184500	1.0462976786749238	[145]	[253]	8	hSpCas9	negative selection	11911206
93896616	93896639	3	-	28162770	MV411	viability	CTTGGCGGAGCAGTTTGCAGGGG	PROS1	ENSG00000184500	0.6241785302995211	[438]	[569]	5	hSpCas9	negative selection	11911207
93893041	93893064	3	-	28162770	MV411	viability	AATCTATCGATCACTCAGCGTGG	PROS1	ENSG00000184500	0.751480056120364	[109]	[155]	6	hSpCas9	negative selection	11911208
93927276	93927299	3	-	28162770	MONOMAC1	viability	GTGCAATAAAGAAGAAGCCAGGG	PROS1	ENSG00000184500	0.11963552237631342	[109]	[136]	1	hSpCas9	negative selection	12080565
93886347	93886370	3	+	28162770	MONOMAC1	viability	GTTCACTTTCCACTTTCCGAGGG	PROS1	ENSG00000184500	-0.03102689562062466	[204]	[229]	0	hSpCas9	negative selection	12080566
93927255	93927278	3	-	28162770	MONOMAC1	viability	GGAGGTCTTTGAAAATGACCCGG	PROS1	ENSG00000184500	0.20151252943072095	[43]	[57]	2	hSpCas9	negative selection	12080567
93884869	93884892	3	+	28162770	MONOMAC1	viability	GTATACATCCATCTAGACGAGGG	PROS1	ENSG00000184500	0.594376531129029	[25]	[44]	6	hSpCas9	negative selection	12080568
93876974	93876997	3	-	28162770	MONOMAC1	viability	AAAGTGGCCACATACCTGGGTGG	PROS1	ENSG00000184500	0.39797931832552547	[142]	[215]	4	hSpCas9	negative selection	12080569
93973724	93973747	3	-	28162770	MONOMAC1	viability	AGGGTCCTGGGTGGGCGCTGCGG	PROS1	ENSG00000184500	0.5578506551039148	[15]	[26]	5	hSpCas9	negative selection	12080570
93927375	93927398	3	-	28162770	MONOMAC1	viability	GCAACAGGCTTCACAAGTCCTGG	PROS1	ENSG00000184500	1.5759392828723526	[90]	[310]	9	hSpCas9	negative selection	12080571
93879235	93879258	3	+	28162770	MONOMAC1	viability	AAGCATAACACCAGTGCCCGTGG	PROS1	ENSG00000184500	0.2307117039688441	[112]	[151]	2	hSpCas9	negative selection	12080572
93896616	93896639	3	-	28162770	MONOMAC1	viability	CTTGGCGGAGCAGTTTGCAGGGG	PROS1	ENSG00000184500	0.7213246839160887	[308]	[583]	7	hSpCas9	negative selection	12080573
93893041	93893064	3	-	28162770	MONOMAC1	viability	AATCTATCGATCACTCAGCGTGG	PROS1	ENSG00000184500	1.3636781074149251	[59]	[176]	9	hSpCas9	negative selection	12080574
93927276	93927299	3	-	28162770	OCIAML2	viability	GTGCAATAAAGAAGAAGCCAGGG	PROS1	ENSG00000184500	0.4849760553993854	[32]	[255]	5	hSpCas9	negative selection	12249931
93886347	93886370	3	+	28162770	OCIAML2	viability	GTTCACTTTCCACTTTCCGAGGG	PROS1	ENSG00000184500	-0.178274845738146	[68]	[337]	-1	hSpCas9	negative selection	12249932
93927255	93927278	3	-	28162770	OCIAML2	viability	GGAGGTCTTTGAAAATGACCCGG	PROS1	ENSG00000184500	0.0529321308148516	[11]	[68]	0	hSpCas9	negative selection	12249933
93884869	93884892	3	+	28162770	OCIAML2	viability	GTATACATCCATCTAGACGAGGG	PROS1	ENSG00000184500	-0.6512020708839821	[16]	[59]	-5	hSpCas9	negative selection	12249934
93876974	93876997	3	-	28162770	OCIAML2	viability	AAAGTGGCCACATACCTGGGTGG	PROS1	ENSG00000184500	0.2546539638764097	[61]	[409]	2	hSpCas9	negative selection	12249935
93973724	93973747	3	-	28162770	OCIAML2	viability	AGGGTCCTGGGTGGGCGCTGCGG	PROS1	ENSG00000184500	0.5882638638114073	[2]	[24]	6	hSpCas9	negative selection	12249936
93927375	93927398	3	-	28162770	OCIAML2	viability	GCAACAGGCTTCACAAGTCCTGG	PROS1	ENSG00000184500	0.44617623923144	[28]	[218]	4	hSpCas9	negative selection	12249937
93879235	93879258	3	+	28162770	OCIAML2	viability	AAGCATAACACCAGTGCCCGTGG	PROS1	ENSG00000184500	0.16495874854896314	[41]	[260]	1	hSpCas9	negative selection	12249938
93896616	93896639	3	-	28162770	OCIAML2	viability	CTTGGCGGAGCAGTTTGCAGGGG	PROS1	ENSG00000184500	0.5150623380739556	[75]	[601]	5	hSpCas9	negative selection	12249939
93893041	93893064	3	-	28162770	OCIAML2	viability	AATCTATCGATCACTCAGCGTGG	PROS1	ENSG00000184500	-1.1049803529254811	[25]	[66]	-6	hSpCas9	negative selection	12249940
93927276	93927299	3	-	28162770	OCIAML3	viability	GTGCAATAAAGAAGAAGCCAGGG	PROS1	ENSG00000184500	0.9060659628104801	[34]	[197]	7	hSpCas9	negative selection	12419297
93886347	93886370	3	+	28162770	OCIAML3	viability	GTTCACTTTCCACTTTCCGAGGG	PROS1	ENSG00000184500	0.6720292536711542	[99]	[480]	6	hSpCas9	negative selection	12419298
93927255	93927278	3	-	28162770	OCIAML3	viability	GGAGGTCTTTGAAAATGACCCGG	PROS1	ENSG00000184500	-0.7360266451965911	[15]	[28]	-5	hSpCas9	negative selection	12419299
93884869	93884892	3	+	28162770	OCIAML3	viability	GTATACATCCATCTAGACGAGGG	PROS1	ENSG00000184500	0.13181739623684252	[12]	[42]	1	hSpCas9	negative selection	12419300
93876974	93876997	3	-	28162770	OCIAML3	viability	AAAGTGGCCACATACCTGGGTGG	PROS1	ENSG00000184500	0.12401639018858279	[68]	[226]	1	hSpCas9	negative selection	12419301
93973724	93973747	3	-	28162770	OCIAML3	viability	AGGGTCCTGGGTGGGCGCTGCGG	PROS1	ENSG00000184500	0.1064320778169292	[3]	[12]	1	hSpCas9	negative selection	12419302
93927375	93927398	3	-	28162770	OCIAML3	viability	GCAACAGGCTTCACAAGTCCTGG	PROS1	ENSG00000184500	-1.1603544628779723	[76]	[103]	-7	hSpCas9	negative selection	12419303
93879235	93879258	3	+	28162770	OCIAML3	viability	AAGCATAACACCAGTGCCCGTGG	PROS1	ENSG00000184500	1.8408145109691327	[42]	[464]	9	hSpCas9	negative selection	12419304
93896616	93896639	3	-	28162770	OCIAML3	viability	CTTGGCGGAGCAGTTTGCAGGGG	PROS1	ENSG00000184500	-0.2374069677820212	[147]	[378]	-2	hSpCas9	negative selection	12419305
93893041	93893064	3	-	28162770	OCIAML3	viability	AATCTATCGATCACTCAGCGTGG	PROS1	ENSG00000184500	-0.15588652793227797	[30]	[83]	-1	hSpCas9	negative selection	12419306