Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:8899
• Symbol:PRPF4B
• Description:pre-mRNA processing factor 4B

DataSource: http://genomecrispr.dkfz.de/#!/results/PRPF4B

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
4040786	4040809	6	+	26472758	Jiyoye	viability	GGAGCAGATCACGCTTGCGAAGG	PRPF4B	ENSG00000112739	-1.4392793602406713	[186]	[51]	-7	hSpCas9	negative selection	128105
4049032	4049055	6	-	26472758	Jiyoye	viability	GAAATCTTTTCCAATGCCAGCGG	PRPF4B	ENSG00000112739	-0.7435035309917949	[241]	[108]	-5	hSpCas9	negative selection	128106
4040806	4040829	6	+	26472758	Jiyoye	viability	AGGCGGTCTCGATCACGCGGTGG	PRPF4B	ENSG00000112739	-0.3297902126603327	[54]	[32]	-2	hSpCas9	negative selection	128107
4021416	4021439	6	+	26472758	Jiyoye	viability	GAAGTTCAAGATGGCCGCCGCGG	PRPF4B	ENSG00000112739	-0.02166791729800091	[139]	[103]	0	hSpCas9	negative selection	128108
4021430	4021453	6	-	26472758	Jiyoye	viability	TAGCGACTGGGTCTCCGCGGCGG	PRPF4B	ENSG00000112739	-0.35466488129936224	[38]	[22]	-3	hSpCas9	negative selection	128109
4032661	4032684	6	-	26472758	Jiyoye	viability	CCAGGAGACAGTGTCCGCGAGGG	PRPF4B	ENSG00000112739	0.43820227712649806	[45]	[46]	3	hSpCas9	negative selection	128110
4031937	4031960	6	+	26472758	Jiyoye	viability	TGAGTCTGGCTCTGAAGAAGAGG	PRPF4B	ENSG00000112739	-1.5375172468150295	[434]	[112]	-7	hSpCas9	negative selection	128111
4032241	4032264	6	-	26472758	Jiyoye	viability	TGAGATCGCCTTCTAAGGGTAGG	PRPF4B	ENSG00000112739	-0.13535185289488627	[66]	[45]	-1	hSpCas9	negative selection	128112
4032713	4032736	6	+	26472758	Jiyoye	viability	GAAAACGACGAGAACCAGAGAGG	PRPF4B	ENSG00000112739	-0.8558590243279203	[11]	[4]	-6	hSpCas9	negative selection	128113
4040765	4040788	6	+	26472758	Jiyoye	viability	TAAATAGGGACAGAGGTCGGAGG	PRPF4B	ENSG00000112739	-0.5711295473948077	[131]	[66]	-4	hSpCas9	negative selection	128114
4040786	4040809	6	+	26472758	KBM7	viability	GGAGCAGATCACGCTTGCGAAGG	PRPF4B	ENSG00000112739	0.33253445211032084	[391,426]	[174,306]	3	hSpCas9	negative selection	319223
4049032	4049055	6	-	26472758	KBM7	viability	GAAATCTTTTCCAATGCCAGCGG	PRPF4B	ENSG00000112739	0.3439539639050089	[858,851]	[657,382]	3	hSpCas9	negative selection	319224
4040806	4040829	6	+	26472758	KBM7	viability	AGGCGGTCTCGATCACGCGGTGG	PRPF4B	ENSG00000112739	-0.11471705654495523	[316,180]	[121,90]	-1	hSpCas9	negative selection	319225
4021416	4021439	6	+	26472758	KBM7	viability	GAAGTTCAAGATGGCCGCCGCGG	PRPF4B	ENSG00000112739	0.9182266963750678	[453,317]	[423,261]	8	hSpCas9	negative selection	319226
4021430	4021453	6	-	26472758	KBM7	viability	TAGCGACTGGGTCTCCGCGGCGG	PRPF4B	ENSG00000112739	0.12936742589556538	[332,187]	[190,76]	1	hSpCas9	negative selection	319227
4032661	4032684	6	-	26472758	KBM7	viability	CCAGGAGACAGTGTCCGCGAGGG	PRPF4B	ENSG00000112739	-0.6585288307202116	[299,262]	[79,86]	-5	hSpCas9	negative selection	319228
4031937	4031960	6	+	26472758	KBM7	viability	TGAGTCTGGCTCTGAAGAAGAGG	PRPF4B	ENSG00000112739	0.6248669844558725	[1122,1059]	[718,858]	6	hSpCas9	negative selection	319229
4032241	4032264	6	-	26472758	KBM7	viability	TGAGATCGCCTTCTAAGGGTAGG	PRPF4B	ENSG00000112739	-0.12010849124566451	[620,492]	[374,117]	-1	hSpCas9	negative selection	319230
4032713	4032736	6	+	26472758	KBM7	viability	GAAAACGACGAGAACCAGAGAGG	PRPF4B	ENSG00000112739	-0.8248752380454261	[87,93]	[45,4]	-6	hSpCas9	negative selection	319231
4040765	4040788	6	+	26472758	KBM7	viability	TAAATAGGGACAGAGGTCGGAGG	PRPF4B	ENSG00000112739	-0.06690250348752169	[916,587]	[456,219]	0	hSpCas9	negative selection	319232
4040786	4040809	6	+	26472758	Raji	viability	GGAGCAGATCACGCTTGCGAAGG	PRPF4B	ENSG00000112739	0.09739944680097745	[144]	[35]	0	hSpCas9	negative selection	510341
4049032	4049055	6	-	26472758	Raji	viability	GAAATCTTTTCCAATGCCAGCGG	PRPF4B	ENSG00000112739	-0.12806503878829467	[517]	[109]	-1	hSpCas9	negative selection	510342
4040806	4040829	6	+	26472758	Raji	viability	AGGCGGTCTCGATCACGCGGTGG	PRPF4B	ENSG00000112739	-1.4775789653475566	[71]	[5]	-8	hSpCas9	negative selection	510343
4021416	4021439	6	+	26472758	Raji	viability	GAAGTTCAAGATGGCCGCCGCGG	PRPF4B	ENSG00000112739	0.6732877002790709	[126]	[46]	6	hSpCas9	negative selection	510344
4021430	4021453	6	-	26472758	Raji	viability	TAGCGACTGGGTCTCCGCGGCGG	PRPF4B	ENSG00000112739	0.6975077412105346	[92]	[34]	6	hSpCas9	negative selection	510345
4032661	4032684	6	-	26472758	Raji	viability	CCAGGAGACAGTGTCCGCGAGGG	PRPF4B	ENSG00000112739	-1.5985943663089228	[260]	[19]	-8	hSpCas9	negative selection	510346
4031937	4031960	6	+	26472758	Raji	viability	TGAGTCTGGCTCTGAAGAAGAGG	PRPF4B	ENSG00000112739	-0.5446931612060939	[747]	[118]	-4	hSpCas9	negative selection	510347
4032241	4032264	6	-	26472758	Raji	viability	TGAGATCGCCTTCTAAGGGTAGG	PRPF4B	ENSG00000112739	-1.9638234151188203	[352]	[20]	-8	hSpCas9	negative selection	510348
4032713	4032736	6	+	26472758	Raji	viability	GAAAACGACGAGAACCAGAGAGG	PRPF4B	ENSG00000112739	1.6923460360947558	[51]	[38]	9	hSpCas9	negative selection	510349
4040765	4040788	6	+	26472758	Raji	viability	TAAATAGGGACAGAGGTCGGAGG	PRPF4B	ENSG00000112739	-1.2977579277627447	[338]	[31]	-7	hSpCas9	negative selection	510350
4040786	4040809	6	+	26472758	K562	viability	GGAGCAGATCACGCTTGCGAAGG	PRPF4B	ENSG00000112739	0.8310676050154897	[284]	[427]	7	hSpCas9	negative selection	701459
4049032	4049055	6	-	26472758	K562	viability	GAAATCTTTTCCAATGCCAGCGG	PRPF4B	ENSG00000112739	-0.10190602152838268	[819]	[644]	0	hSpCas9	negative selection	701460
4040806	4040829	6	+	26472758	K562	viability	AGGCGGTCTCGATCACGCGGTGG	PRPF4B	ENSG00000112739	0.3919759160803049	[194]	[215]	3	hSpCas9	negative selection	701461
4021416	4021439	6	+	26472758	K562	viability	GAAGTTCAAGATGGCCGCCGCGG	PRPF4B	ENSG00000112739	0.7907599343602957	[264]	[386]	6	hSpCas9	negative selection	701462
4021430	4021453	6	-	26472758	K562	viability	TAGCGACTGGGTCTCCGCGGCGG	PRPF4B	ENSG00000112739	-0.1798373016417758	[156]	[116]	-1	hSpCas9	negative selection	701463
4032661	4032684	6	-	26472758	K562	viability	CCAGGAGACAGTGTCCGCGAGGG	PRPF4B	ENSG00000112739	0.6682264365730228	[204]	[274]	5	hSpCas9	negative selection	701464
4031937	4031960	6	+	26472758	K562	viability	TGAGTCTGGCTCTGAAGAAGAGG	PRPF4B	ENSG00000112739	0.6644156510140522	[1088]	[1456]	5	hSpCas9	negative selection	701465
4032241	4032264	6	-	26472758	K562	viability	TGAGATCGCCTTCTAAGGGTAGG	PRPF4B	ENSG00000112739	0.24441872766644684	[450]	[450]	1	hSpCas9	negative selection	701466
4032713	4032736	6	+	26472758	K562	viability	GAAAACGACGAGAACCAGAGAGG	PRPF4B	ENSG00000112739	2.348041358740604	[46]	[201]	9	hSpCas9	negative selection	701467
4040765	4040788	6	+	26472758	K562	viability	TAAATAGGGACAGAGGTCGGAGG	PRPF4B	ENSG00000112739	0.7009585933995338	[453]	[622]	6	hSpCas9	negative selection	701468
4021430	4021453	6	-	26627737	DLD1	viability	TAGCGACTGGGTCTCCGCGGCGG	PRPF4B	ENSG00000112739	-1.5766169055034691	[237]	[20,28,24]	-8	hSpCas9	negative selection	832809
4021443	4021466	6	-	26627737	DLD1	viability	CTGGCTGCTCCCGTAGCGACTGG	PRPF4B	ENSG00000112739	-0.5475653266275413	[1230]	[421,245,139]	-5	hSpCas9	negative selection	832810
4032661	4032684	6	-	26627737	DLD1	viability	CCAGGAGACAGTGTCCGCGAGGG	PRPF4B	ENSG00000112739	-2.633925130145565	[1734]	[91,53,110]	-9	hSpCas9	negative selection	832811
4032662	4032685	6	-	26627737	DLD1	viability	CCCAGGAGACAGTGTCCGCGAGG	PRPF4B	ENSG00000112739	-1.535567936323972	[1933]	[347,218,78]	-8	hSpCas9	negative selection	832812
4040803	4040826	6	+	26627737	DLD1	viability	CGAAGGCGGTCTCGATCACGCGG	PRPF4B	ENSG00000112739	1.4367097361032888	[45]	[10,26,72]	9	hSpCas9	negative selection	832818
4049016	4049039	6	+	26627737	DLD1	viability	AGTGCTCGTCTTCGGGCCGCTGG	PRPF4B	ENSG00000112739	-5.497462962298881	[190]	[1,0,0]	-9	hSpCas9	negative selection	832819
4021430	4021453	6	-	26627737	GBM cells	viability after 5 days	TAGCGACTGGGTCTCCGCGGCGG	PRPF4B	ENSG00000112739	-1.8559736272777831	[107]	[17,13]	-9	hSpCas9	negative selection	915124
4021443	4021466	6	-	26627737	GBM cells	viability after 5 days	CTGGCTGCTCCCGTAGCGACTGG	PRPF4B	ENSG00000112739	-0.29689154395003836	[456]	[198,199]	-4	hSpCas9	negative selection	915125
4032661	4032684	6	-	26627737	GBM cells	viability after 5 days	CCAGGAGACAGTGTCCGCGAGGG	PRPF4B	ENSG00000112739	-1.5255839536422247	[458]	[75,94]	-9	hSpCas9	negative selection	915126
4032662	4032685	6	-	26627737	GBM cells	viability after 5 days	CCCAGGAGACAGTGTCCGCGAGG	PRPF4B	ENSG00000112739	-0.24103377996704745	[767]	[330,365]	-4	hSpCas9	negative selection	915127
4040803	4040826	6	+	26627737	GBM cells	viability after 5 days	CGAAGGCGGTCTCGATCACGCGG	PRPF4B	ENSG00000112739	-0.18052059260871944	[55]	[33,18]	-3	hSpCas9	negative selection	915133
4049016	4049039	6	+	26627737	GBM cells	viability after 5 days	AGTGCTCGTCTTCGGGCCGCTGG	PRPF4B	ENSG00000112739	0.1399219743894804	[43]	[24,26]	2	hSpCas9	negative selection	915134
4021430	4021453	6	-	26627737	GBM cells	viability after 13 days	TAGCGACTGGGTCTCCGCGGCGG	PRPF4B	ENSG00000112739	-2.995906352042942	[107]	[8,5]	-9	hSpCas9	negative selection	997439
4021443	4021466	6	-	26627737	GBM cells	viability after 13 days	CTGGCTGCTCCCGTAGCGACTGG	PRPF4B	ENSG00000112739	-0.18634695436233795	[456]	[250,190]	-2	hSpCas9	negative selection	997440
4032661	4032684	6	-	26627737	GBM cells	viability after 13 days	CCAGGAGACAGTGTCCGCGAGGG	PRPF4B	ENSG00000112739	-1.4679227315587084	[458]	[78,98]	-9	hSpCas9	negative selection	997441
4032662	4032685	6	-	26627737	GBM cells	viability after 13 days	CCCAGGAGACAGTGTCCGCGAGG	PRPF4B	ENSG00000112739	-0.339143309934439	[767]	[308,345]	-4	hSpCas9	negative selection	997442
4040803	4040826	6	+	26627737	GBM cells	viability after 13 days	CGAAGGCGGTCTCGATCACGCGG	PRPF4B	ENSG00000112739	-0.07093339745096561	[55]	[18,36]	-1	hSpCas9	negative selection	997448
4049016	4049039	6	+	26627737	GBM cells	viability after 13 days	AGTGCTCGTCTTCGGGCCGCTGG	PRPF4B	ENSG00000112739	0.3579232367355698	[43]	[50,13]	4	hSpCas9	negative selection	997449
4021430	4021453	6	-	26627737	GBM cells	viability after 21 days	TAGCGACTGGGTCTCCGCGGCGG	PRPF4B	ENSG00000112739	-1.329646852204439	[107]	[26,19]	-8	hSpCas9	negative selection	1079754
4021443	4021466	6	-	26627737	GBM cells	viability after 21 days	CTGGCTGCTCCCGTAGCGACTGG	PRPF4B	ENSG00000112739	-0.540685633762513	[456]	[189,152]	-5	hSpCas9	negative selection	1079755
4032661	4032684	6	-	26627737	GBM cells	viability after 21 days	CCAGGAGACAGTGTCCGCGAGGG	PRPF4B	ENSG00000112739	-1.5293431802224968	[458]	[88,83]	-8	hSpCas9	negative selection	1079756
4032662	4032685	6	-	26627737	GBM cells	viability after 21 days	CCCAGGAGACAGTGTCCGCGAGG	PRPF4B	ENSG00000112739	-0.6077505647349604	[767]	[301,247]	-5	hSpCas9	negative selection	1079757
4040803	4040826	6	+	26627737	GBM cells	viability after 21 days	CGAAGGCGGTCTCGATCACGCGG	PRPF4B	ENSG00000112739	0.6591760889630298	[55]	[46,48]	6	hSpCas9	negative selection	1079763
4049016	4049039	6	+	26627737	GBM cells	viability after 21 days	AGTGCTCGTCTTCGGGCCGCTGG	PRPF4B	ENSG00000112739	-0.8458439784078116	[43]	[17,8]	-6	hSpCas9	negative selection	1079764
4021430	4021453	6	-	26627737	RPE1	viability after 9 days	TAGCGACTGGGTCTCCGCGGCGG	PRPF4B	ENSG00000112739	6.177648021533584	[0]	[9,38]	9	hSpCas9	negative selection	1162069
4021443	4021466	6	-	26627737	RPE1	viability after 9 days	CTGGCTGCTCCCGTAGCGACTGG	PRPF4B	ENSG00000112739	-1.7245079541491573	[1701]	[186,127]	-8	hSpCas9	negative selection	1162070
4032661	4032684	6	-	26627737	RPE1	viability after 9 days	CCAGGAGACAGTGTCCGCGAGGG	PRPF4B	ENSG00000112739	-3.8283773496308777	[1366]	[30,28]	-9	hSpCas9	negative selection	1162071
4032662	4032685	6	-	26627737	RPE1	viability after 9 days	CCCAGGAGACAGTGTCCGCGAGG	PRPF4B	ENSG00000112739	-1.1842556425537374	[1765]	[203,293]	-7	hSpCas9	negative selection	1162072
4040803	4040826	6	+	26627737	RPE1	viability after 9 days	CGAAGGCGGTCTCGATCACGCGG	PRPF4B	ENSG00000112739	-0.16939299955823017	[161]	[0,101]	-1	hSpCas9	negative selection	1162078
4049016	4049039	6	+	26627737	RPE1	viability after 9 days	AGTGCTCGTCTTCGGGCCGCTGG	PRPF4B	ENSG00000112739	-3.962007156166938	[189]	[5,0]	-9	hSpCas9	negative selection	1162079
4021430	4021453	6	-	26627737	RPE1	viability after 12 days	TAGCGACTGGGTCTCCGCGGCGG	PRPF4B	ENSG00000112739	1.8961114116731377	[0]	[0,0]	8	hSpCas9	negative selection	1244384
4021443	4021466	6	-	26627737	RPE1	viability after 12 days	CTGGCTGCTCCCGTAGCGACTGG	PRPF4B	ENSG00000112739	-1.7271851691922087	[1701]	[107,169]	-8	hSpCas9	negative selection	1244385
4032661	4032684	6	-	26627737	RPE1	viability after 12 days	CCAGGAGACAGTGTCCGCGAGGG	PRPF4B	ENSG00000112739	-2.565160745073527	[1366]	[46,77]	-9	hSpCas9	negative selection	1244386
4032662	4032685	6	-	26627737	RPE1	viability after 12 days	CCCAGGAGACAGTGTCCGCGAGG	PRPF4B	ENSG00000112739	-1.4151196690430223	[1765]	[191,162]	-7	hSpCas9	negative selection	1244387
4040803	4040826	6	+	26627737	RPE1	viability after 12 days	CGAAGGCGGTCTCGATCACGCGG	PRPF4B	ENSG00000112739	-0.6393309532042193	[161]	[8,47]	-4	hSpCas9	negative selection	1244393
4049016	4049039	6	+	26627737	RPE1	viability after 12 days	AGTGCTCGTCTTCGGGCCGCTGG	PRPF4B	ENSG00000112739	-2.244606500334112	[189]	[19,0]	-8	hSpCas9	negative selection	1244394
4021430	4021453	6	-	26627737	RPE1	viability after 15 days	TAGCGACTGGGTCTCCGCGGCGG	PRPF4B	ENSG00000112739	3.397980969488515	[0]	[3,1]	9	hSpCas9	negative selection	1326699
4021443	4021466	6	-	26627737	RPE1	viability after 15 days	CTGGCTGCTCCCGTAGCGACTGG	PRPF4B	ENSG00000112739	-1.960944774054644	[1701]	[57,186]	-8	hSpCas9	negative selection	1326700
4032661	4032684	6	-	26627737	RPE1	viability after 15 days	CCAGGAGACAGTGTCCGCGAGGG	PRPF4B	ENSG00000112739	-3.2646589800986074	[1366]	[26,52]	-9	hSpCas9	negative selection	1326701
4032662	4032685	6	-	26627737	RPE1	viability after 15 days	CCCAGGAGACAGTGTCCGCGAGG	PRPF4B	ENSG00000112739	-1.3738067049406117	[1765]	[233,152]	-7	hSpCas9	negative selection	1326702
4040803	4040826	6	+	26627737	RPE1	viability after 15 days	CGAAGGCGGTCTCGATCACGCGG	PRPF4B	ENSG00000112739	-0.7937570455749827	[161]	[1,49]	-5	hSpCas9	negative selection	1326708
4049016	4049039	6	+	26627737	RPE1	viability after 15 days	AGTGCTCGTCTTCGGGCCGCTGG	PRPF4B	ENSG00000112739	-3.033674713652487	[189]	[2,9]	-9	hSpCas9	negative selection	1326709
4021430	4021453	6	-	26627737	RPE1	viability after 18 days	TAGCGACTGGGTCTCCGCGGCGG	PRPF4B	ENSG00000112739	7.3007474523091025	[0]	[43,40]	9	hSpCas9	negative selection	1409014
4021443	4021466	6	-	26627737	RPE1	viability after 18 days	CTGGCTGCTCCCGTAGCGACTGG	PRPF4B	ENSG00000112739	-2.2828783910408568	[1701]	[90,97]	-8	hSpCas9	negative selection	1409015
4032661	4032684	6	-	26627737	RPE1	viability after 18 days	CCAGGAGACAGTGTCCGCGAGGG	PRPF4B	ENSG00000112739	-5.089618767998024	[1366]	[5,15]	-9	hSpCas9	negative selection	1409016
4032662	4032685	6	-	26627737	RPE1	viability after 18 days	CCCAGGAGACAGTGTCCGCGAGG	PRPF4B	ENSG00000112739	-1.0663828170784648	[1765]	[156,302]	-6	hSpCas9	negative selection	1409017
4040803	4040826	6	+	26627737	RPE1	viability after 18 days	CGAAGGCGGTCTCGATCACGCGG	PRPF4B	ENSG00000112739	-2.1670604651728724	[161]	[1,17]	-8	hSpCas9	negative selection	1409023
4049016	4049039	6	+	26627737	RPE1	viability after 18 days	AGTGCTCGTCTTCGGGCCGCTGG	PRPF4B	ENSG00000112739	-1.7293032648455262	[189]	[28,0]	-8	hSpCas9	negative selection	1409024
4021430	4021453	6	-	26627737	HeLa	viability after 8 days	TAGCGACTGGGTCTCCGCGGCGG	PRPF4B	ENSG00000112739	-1.152275698889972	[210]	[96,9,29]	-8	hSpCas9	negative selection	1491329
4021443	4021466	6	-	26627737	HeLa	viability after 8 days	CTGGCTGCTCCCGTAGCGACTGG	PRPF4B	ENSG00000112739	-0.19537578626871377	[1042]	[514,374,329]	-2	hSpCas9	negative selection	1491330
4032661	4032684	6	-	26627737	HeLa	viability after 8 days	CCAGGAGACAGTGTCCGCGAGGG	PRPF4B	ENSG00000112739	-0.7001338172225178	[1029]	[390,186,274]	-6	hSpCas9	negative selection	1491331
4032662	4032685	6	-	26627737	HeLa	viability after 8 days	CCCAGGAGACAGTGTCCGCGAGG	PRPF4B	ENSG00000112739	-0.0036072884794442484	[1200]	[671,580,355]	0	hSpCas9	negative selection	1491332
4040803	4040826	6	+	26627737	HeLa	viability after 8 days	CGAAGGCGGTCTCGATCACGCGG	PRPF4B	ENSG00000112739	-0.3004650915075193	[190]	[37,90,66]	-3	hSpCas9	negative selection	1491338
4049016	4049039	6	+	26627737	HeLa	viability after 8 days	AGTGCTCGTCTTCGGGCCGCTGG	PRPF4B	ENSG00000112739	1.0066921606167527	[87]	[147,73,27]	7	hSpCas9	negative selection	1491339
4021430	4021453	6	-	26627737	HeLa	viability after 12 days	TAGCGACTGGGTCTCCGCGGCGG	PRPF4B	ENSG00000112739	-1.0045554135173487	[210]	[89,40,0]	-7	hSpCas9	negative selection	1573644
4021443	4021466	6	-	26627737	HeLa	viability after 12 days	CTGGCTGCTCCCGTAGCGACTGG	PRPF4B	ENSG00000112739	-0.3327641886451602	[1042]	[373,357,293]	-3	hSpCas9	negative selection	1573645
4032661	4032684	6	-	26627737	HeLa	viability after 12 days	CCAGGAGACAGTGTCCGCGAGGG	PRPF4B	ENSG00000112739	-1.637145920944654	[1029]	[128,35,255]	-9	hSpCas9	negative selection	1573646
4032662	4032685	6	-	26627737	HeLa	viability after 12 days	CCCAGGAGACAGTGTCCGCGAGG	PRPF4B	ENSG00000112739	-0.05692446375740068	[1200]	[465,439,528]	0	hSpCas9	negative selection	1573647
4040803	4040826	6	+	26627737	HeLa	viability after 12 days	CGAAGGCGGTCTCGATCACGCGG	PRPF4B	ENSG00000112739	-1.0548978567106106	[190]	[45,39,27]	-7	hSpCas9	negative selection	1573653
4049016	4049039	6	+	26627737	HeLa	viability after 12 days	AGTGCTCGTCTTCGGGCCGCTGG	PRPF4B	ENSG00000112739	-0.17976634996247798	[87]	[14,20,60]	-1	hSpCas9	negative selection	1573654
4021430	4021453	6	-	26627737	HeLa	viability after 15 days	TAGCGACTGGGTCTCCGCGGCGG	PRPF4B	ENSG00000112739	-1.4496958004367446	[210]	[6,39,48]	-8	hSpCas9	negative selection	1655959
4021443	4021466	6	-	26627737	HeLa	viability after 15 days	CTGGCTGCTCCCGTAGCGACTGG	PRPF4B	ENSG00000112739	-0.12558889564794407	[1042]	[364,412,389]	-1	hSpCas9	negative selection	1655960
4032661	4032684	6	-	26627737	HeLa	viability after 15 days	CCAGGAGACAGTGTCCGCGAGGG	PRPF4B	ENSG00000112739	-0.851144863297557	[1029]	[115,118,482]	-6	hSpCas9	negative selection	1655961
4032662	4032685	6	-	26627737	HeLa	viability after 15 days	CCCAGGAGACAGTGTCCGCGAGG	PRPF4B	ENSG00000112739	0.30607195570604473	[1200]	[512,583,726]	2	hSpCas9	negative selection	1655962
4040803	4040826	6	+	26627737	HeLa	viability after 15 days	CGAAGGCGGTCTCGATCACGCGG	PRPF4B	ENSG00000112739	-0.04972836286066018	[190]	[74,127,17]	0	hSpCas9	negative selection	1655968
4049016	4049039	6	+	26627737	HeLa	viability after 15 days	AGTGCTCGTCTTCGGGCCGCTGG	PRPF4B	ENSG00000112739	1.00485343628083	[87]	[55,1,164]	7	hSpCas9	negative selection	1655969
4021430	4021453	6	-	26627737	HeLa	viability after 18 days	TAGCGACTGGGTCTCCGCGGCGG	PRPF4B	ENSG00000112739	-1.4077085869357648	[210]	[4,34,48]	-8	hSpCas9	negative selection	1738274
4021443	4021466	6	-	26627737	HeLa	viability after 18 days	CTGGCTGCTCCCGTAGCGACTGG	PRPF4B	ENSG00000112739	-0.12422291005381125	[1042]	[255,328,389]	-1	hSpCas9	negative selection	1738275
4032661	4032684	6	-	26627737	HeLa	viability after 18 days	CCAGGAGACAGTGTCCGCGAGGG	PRPF4B	ENSG00000112739	-0.8456044346776885	[1029]	[79,97,482]	-6	hSpCas9	negative selection	1738276
4032662	4032685	6	-	26627737	HeLa	viability after 18 days	CCCAGGAGACAGTGTCCGCGAGG	PRPF4B	ENSG00000112739	0.2919418869242416	[1200]	[333,481,726]	2	hSpCas9	negative selection	1738277
4040803	4040826	6	+	26627737	HeLa	viability after 18 days	CGAAGGCGGTCTCGATCACGCGG	PRPF4B	ENSG00000112739	-0.039030065968940875	[190]	[48,108,17]	0	hSpCas9	negative selection	1738283
4049016	4049039	6	+	26627737	HeLa	viability after 18 days	AGTGCTCGTCTTCGGGCCGCTGG	PRPF4B	ENSG00000112739	1.0222959876732431	[87]	[38,1,164]	7	hSpCas9	negative selection	1738284
4021430	4021453	6	-	26627737	HCT116	viability after 6 days	TAGCGACTGGGTCTCCGCGGCGG	PRPF4B	ENSG00000112739	-0.10806562682445658	[474]	[96,53]	0	hSpCas9	negative selection	1820589
4021443	4021466	6	-	26627737	HCT116	viability after 6 days	CTGGCTGCTCCCGTAGCGACTGG	PRPF4B	ENSG00000112739	1.5187559610049144	[841]	[212,470]	7	hSpCas9	negative selection	1820590
4032661	4032684	6	-	26627737	HCT116	viability after 6 days	CCAGGAGACAGTGTCCGCGAGGG	PRPF4B	ENSG00000112739	-1.1532926761394164	[1548]	[278,15]	-6	hSpCas9	negative selection	1820591
4032662	4032685	6	-	26627737	HCT116	viability after 6 days	CCCAGGAGACAGTGTCCGCGAGG	PRPF4B	ENSG00000112739	0.50967431859649	[2533]	[396,660]	3	hSpCas9	negative selection	1820592
4040803	4040826	6	+	26627737	HCT116	viability after 6 days	CGAAGGCGGTCTCGATCACGCGG	PRPF4B	ENSG00000112739	0.006049044672804982	[286]	[63,34]	0	hSpCas9	negative selection	1820598
4049016	4049039	6	+	26627737	HCT116	viability after 6 days	AGTGCTCGTCTTCGGGCCGCTGG	PRPF4B	ENSG00000112739	-0.22105044000016427	[228]	[46,21]	-1	hSpCas9	negative selection	1820599
4021430	4021453	6	-	26627737	HCT116	viability after 8 days	TAGCGACTGGGTCTCCGCGGCGG	PRPF4B	ENSG00000112739	-0.8705893599641737	[182]	[37,59,66]	-8	hSpCas9	negative selection	1902904
4021443	4021466	6	-	26627737	HCT116	viability after 8 days	CTGGCTGCTCCCGTAGCGACTGG	PRPF4B	ENSG00000112739	0.2206376532415617	[589]	[259,382,489]	2	hSpCas9	negative selection	1902905
4032661	4032684	6	-	26627737	HCT116	viability after 8 days	CCAGGAGACAGTGTCCGCGAGGG	PRPF4B	ENSG00000112739	-0.008885848620494907	[292]	[150,234,95]	0	hSpCas9	negative selection	1902906
4032662	4032685	6	-	26627737	HCT116	viability after 8 days	CCCAGGAGACAGTGTCCGCGAGG	PRPF4B	ENSG00000112739	-0.5808548875110715	[1058]	[392,349,426]	-6	hSpCas9	negative selection	1902907
4040803	4040826	6	+	26627737	HCT116	viability after 8 days	CGAAGGCGGTCTCGATCACGCGG	PRPF4B	ENSG00000112739	0.7166541601366805	[42]	[47,31,36]	6	hSpCas9	negative selection	1902913
4049016	4049039	6	+	26627737	HCT116	viability after 8 days	AGTGCTCGTCTTCGGGCCGCTGG	PRPF4B	ENSG00000112739	1.304470209241521	[35]	[59,22,63]	9	hSpCas9	negative selection	1902914
4021430	4021453	6	-	26627737	HCT116	viability after 9 days	TAGCGACTGGGTCTCCGCGGCGG	PRPF4B	ENSG00000112739	-2.7932352339187947	[474]	[24,12]	-9	hSpCas9	negative selection	1985219
4021443	4021466	6	-	26627737	HCT116	viability after 9 days	CTGGCTGCTCCCGTAGCGACTGG	PRPF4B	ENSG00000112739	0.40626381755731905	[841]	[202,372]	3	hSpCas9	negative selection	1985220
4032661	4032684	6	-	26627737	HCT116	viability after 9 days	CCAGGAGACAGTGTCCGCGAGGG	PRPF4B	ENSG00000112739	-1.2795331636086735	[1548]	[347,29]	-7	hSpCas9	negative selection	1985221
4032662	4032685	6	-	26627737	HCT116	viability after 9 days	CCCAGGAGACAGTGTCCGCGAGG	PRPF4B	ENSG00000112739	-0.3296619138288257	[2533]	[710,401]	-2	hSpCas9	negative selection	1985222
4040803	4040826	6	+	26627737	HCT116	viability after 9 days	CGAAGGCGGTCTCGATCACGCGG	PRPF4B	ENSG00000112739	-1.97818545364982	[286]	[38,3]	-8	hSpCas9	negative selection	1985228
4049016	4049039	6	+	26627737	HCT116	viability after 9 days	AGTGCTCGTCTTCGGGCCGCTGG	PRPF4B	ENSG00000112739	-0.056425519129548185	[228]	[12,94]	0	hSpCas9	negative selection	1985229
4021430	4021453	6	-	26627737	HCT116	viability after 12 days	TAGCGACTGGGTCTCCGCGGCGG	PRPF4B	ENSG00000112739	0.10930159964507768	[182]	[50,150,114]	1	hSpCas9	negative selection	2067534
4021443	4021466	6	-	26627737	HCT116	viability after 12 days	CTGGCTGCTCCCGTAGCGACTGG	PRPF4B	ENSG00000112739	0.12795030148348374	[589]	[224,402,399]	1	hSpCas9	negative selection	2067535
4032661	4032684	6	-	26627737	HCT116	viability after 12 days	CCAGGAGACAGTGTCCGCGAGGG	PRPF4B	ENSG00000112739	-0.43419390947393677	[292]	[136,160,42]	-5	hSpCas9	negative selection	2067536
4032662	4032685	6	-	26627737	HCT116	viability after 12 days	CCCAGGAGACAGTGTCCGCGAGG	PRPF4B	ENSG00000112739	-0.847694628186245	[1058]	[221,250,460]	-7	hSpCas9	negative selection	2067537
4040803	4040826	6	+	26627737	HCT116	viability after 12 days	CGAAGGCGGTCTCGATCACGCGG	PRPF4B	ENSG00000112739	0.021354828963835448	[42]	[30,18,17]	0	hSpCas9	negative selection	2067543
4049016	4049039	6	+	26627737	HCT116	viability after 12 days	AGTGCTCGTCTTCGGGCCGCTGG	PRPF4B	ENSG00000112739	0.8155635957091412	[35]	[81,7,4]	7	hSpCas9	negative selection	2067544
4021430	4021453	6	-	26627737	HCT116	viability after 15 days	TAGCGACTGGGTCTCCGCGGCGG	PRPF4B	ENSG00000112739	-0.9991307315574026	[182]	[22,66,63]	-7	hSpCas9	negative selection	2149849
4021443	4021466	6	-	26627737	HCT116	viability after 15 days	CTGGCTGCTCCCGTAGCGACTGG	PRPF4B	ENSG00000112739	0.1381329160905509	[589]	[350,393,370]	1	hSpCas9	negative selection	2149850
4032661	4032684	6	-	26627737	HCT116	viability after 15 days	CCAGGAGACAGTGTCCGCGAGGG	PRPF4B	ENSG00000112739	-0.12783118421659698	[292]	[203,185,78]	-1	hSpCas9	negative selection	2149851
4032662	4032685	6	-	26627737	HCT116	viability after 15 days	CCCAGGAGACAGTGTCCGCGAGG	PRPF4B	ENSG00000112739	-0.754160924306009	[1058]	[183,493,381]	-6	hSpCas9	negative selection	2149852
4040803	4040826	6	+	26627737	HCT116	viability after 15 days	CGAAGGCGGTCTCGATCACGCGG	PRPF4B	ENSG00000112739	0.2966040558995835	[42]	[53,19,19]	3	hSpCas9	negative selection	2149858
4049016	4049039	6	+	26627737	HCT116	viability after 15 days	AGTGCTCGTCTTCGGGCCGCTGG	PRPF4B	ENSG00000112739	1.4355623113374074	[35]	[82,26,60]	9	hSpCas9	negative selection	2149859
4021430	4021453	6	-	26627737	HCT116	viability after 18 days	TAGCGACTGGGTCTCCGCGGCGG	PRPF4B	ENSG00000112739	-0.05505389822357387	[182]	[49,77,129]	0	hSpCas9	negative selection	2232164
4021443	4021466	6	-	26627737	HCT116	viability after 18 days	CTGGCTGCTCCCGTAGCGACTGG	PRPF4B	ENSG00000112739	0.38834427669457705	[589]	[223,511,374]	3	hSpCas9	negative selection	2232165
4032661	4032684	6	-	26627737	HCT116	viability after 18 days	CCAGGAGACAGTGTCCGCGAGGG	PRPF4B	ENSG00000112739	-0.7988356177359734	[292]	[102,91,46]	-6	hSpCas9	negative selection	2232166
4032662	4032685	6	-	26627737	HCT116	viability after 18 days	CCCAGGAGACAGTGTCCGCGAGG	PRPF4B	ENSG00000112739	-0.654575727851753	[1058]	[132,298,555]	-5	hSpCas9	negative selection	2232167
4040803	4040826	6	+	26627737	HCT116	viability after 18 days	CGAAGGCGGTCTCGATCACGCGG	PRPF4B	ENSG00000112739	-0.3866713739919829	[42]	[45,0,0]	-4	hSpCas9	negative selection	2232173
4049016	4049039	6	+	26627737	HCT116	viability after 18 days	AGTGCTCGTCTTCGGGCCGCTGG	PRPF4B	ENSG00000112739	2.1703324269650666	[35]	[151,73,5]	9	hSpCas9	negative selection	2232174
4021416	4021439	6	+	24336569	HL60	viability	GAAGTTCAAGATGGCCGCCGCGG	PRPF4B	ENSG00000112739	1.2569008840691398	[191]	[970]	8	hSpCas9	negative selection	2286792
4021430	4021453	6	-	24336569	HL60	viability	TAGCGACTGGGTCTCCGCGGCGG	PRPF4B	ENSG00000112739	-0.5001128534601191	[799]	[1196]	-4	hSpCas9	negative selection	2286793
4021442	4021465	6	-	24336569	HL60	viability	TGGCTGCTCCCGTAGCGACTGGG	PRPF4B	ENSG00000112739	0.43369860910515845	[733]	[2097]	4	hSpCas9	negative selection	2286794
4031696	4031719	6	-	24336569	HL60	viability	TTTATCCTTGTCTTCTTCTGAGG	PRPF4B	ENSG00000112739	-0.213953038027135	[358]	[654]	-2	hSpCas9	negative selection	2286795
4031766	4031789	6	+	24336569	HL60	viability	TATTGATGCTTCTGATAAAGAGG	PRPF4B	ENSG00000112739	1.1787574372820313	[491]	[2356]	8	hSpCas9	negative selection	2286796
4031870	4031893	6	-	24336569	HL60	viability	CATTAACTCATTATCAAGTTCGG	PRPF4B	ENSG00000112739	0.11327197780468623	[947]	[2169]	1	hSpCas9	negative selection	2286797
4031875	4031898	6	+	24336569	HL60	viability	CTTGATAATGAGTTAATGGAAGG	PRPF4B	ENSG00000112739	0.19146696036390612	[568]	[1374]	1	hSpCas9	negative selection	2286798
4031880	4031903	6	+	24336569	HL60	viability	TAATGAGTTAATGGAAGGAAAGG	PRPF4B	ENSG00000112739	0.7778154156026256	[650]	[2361]	6	hSpCas9	negative selection	2286799
4031937	4031960	6	+	24336569	HL60	viability	TGAGTCTGGCTCTGAAGAAGAGG	PRPF4B	ENSG00000112739	0.7275386743101901	[374]	[1313]	6	hSpCas9	negative selection	2286800
4032080	4032103	6	+	24336569	HL60	viability	CCAAAGAACGGACTAGACATAGG	PRPF4B	ENSG00000112739	0.011645303762585213	[1124]	[2399]	0	hSpCas9	negative selection	2286801
4021416	4021439	6	+	24336569	KBM7	viability	GAAGTTCAAGATGGCCGCCGCGG	PRPF4B	ENSG00000112739	0.7206922860409162	[290]	[1307]	6	hSpCas9	negative selection	2353969
4021430	4021453	6	-	24336569	KBM7	viability	TAGCGACTGGGTCTCCGCGGCGG	PRPF4B	ENSG00000112739	0.18629290465322018	[289]	[899]	1	hSpCas9	negative selection	2353970
4021442	4021465	6	-	24336569	KBM7	viability	TGGCTGCTCCCGTAGCGACTGGG	PRPF4B	ENSG00000112739	1.5952588970888335	[252]	[2084]	9	hSpCas9	negative selection	2353971
4031696	4031719	6	-	24336569	KBM7	viability	TTTATCCTTGTCTTCTTCTGAGG	PRPF4B	ENSG00000112739	1.138038330308788	[366]	[2202]	8	hSpCas9	negative selection	2353972
4031766	4031789	6	+	24336569	KBM7	viability	TATTGATGCTTCTGATAAAGAGG	PRPF4B	ENSG00000112739	0.0986572496256874	[515]	[1506]	0	hSpCas9	negative selection	2353973
4031870	4031893	6	-	24336569	KBM7	viability	CATTAACTCATTATCAAGTTCGG	PRPF4B	ENSG00000112739	-0.14348213409320243	[634]	[1567]	-1	hSpCas9	negative selection	2353974
4031875	4031898	6	+	24336569	KBM7	viability	CTTGATAATGAGTTAATGGAAGG	PRPF4B	ENSG00000112739	-0.4462962306654094	[561]	[1124]	-4	hSpCas9	negative selection	2353975
4031880	4031903	6	+	24336569	KBM7	viability	TAATGAGTTAATGGAAGGAAAGG	PRPF4B	ENSG00000112739	-0.580116467405468	[637]	[1163]	-5	hSpCas9	negative selection	2353976
4031937	4031960	6	+	24336569	KBM7	viability	TGAGTCTGGCTCTGAAGAAGAGG	PRPF4B	ENSG00000112739	0.2308821524967149	[462]	[1481]	2	hSpCas9	negative selection	2353977
4032080	4032103	6	+	24336569	KBM7	viability	CCAAAGAACGGACTAGACATAGG	PRPF4B	ENSG00000112739	0.5046832410182938	[890]	[3447]	4	hSpCas9	negative selection	2353978
4048234	4048257	6	-	25494202	A375	resistance to PLX-4720 (puromycin)	CAGGCGCCCGCCACCACGTCCGG	PRPF4B	ENSG00000112739	1.5618735705212097	[103,49]	[83,12]	6	dCas9-VP64	positive selection	2398361
4028262	4028285	6	+	25494202	A375	resistance to PLX-4720 (puromycin)	TCACTGCAGCCTTTAACTCCTGG	PRPF4B	ENSG00000112739	-1.7142589782577375	[182,184]	[19,3]	-8	dCas9-VP64	positive selection	2429870
4035422	4035445	6	+	25494202	A375	resistance to PLX-4720 (puromycin)	CAGGCGTGAGCCACCGCACCCAG	PRPF4B	ENSG00000112739	0.9167831099864405	[164,216]	[6,157]	4	dCas9-VP64	positive selection	2444442
4048234	4048257	6	-	25494202	A375	resistance to PLX-4720 (zeocin)	CAGGCGCCCGCCACCACGTCCGG	PRPF4B	ENSG00000112739	0.22222393386236713	[95,81]	[49,17]	1	dCas9-VP64	positive selection	2493616
4028262	4028285	6	+	25494202	A375	resistance to PLX-4720 (zeocin)	TCACTGCAGCCTTTAACTCCTGG	PRPF4B	ENSG00000112739	-1.495187672432472	[104,314]	[26,20]	-9	dCas9-VP64	positive selection	2525125
4035422	4035445	6	+	25494202	A375	resistance to PLX-4720 (zeocin)	CAGGCGTGAGCCACCGCACCCAG	PRPF4B	ENSG00000112739	0.9421040719499846	[89,134]	[114,27]	6	dCas9-VP64	positive selection	2539697
4032444	4032467	6	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CCAAAGAGAGAAAATCAAAACGG	PRPF4B	ENSG00000112739	-0.004716448810848012	[3,3]	[3,1]	0	hSpCas9	positive selection	3013901
4032592	4032615	6	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CTTCTTCTTGATTTATCACGTGG	PRPF4B	ENSG00000112739	0.344207387372569	[4,4]	[4,5]	7	hSpCas9	positive selection	3013902
4032069	4032092	6	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GTAAAAGCAGATCCAAAGAACGG	PRPF4B	ENSG00000112739	-1.0158206570931314	[2,2]	[1,0]	-9	hSpCas9	positive selection	3013903
4037487	4037510	6	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GTAGATCTCCCATTAGAAGGAGG	PRPF4B	ENSG00000112739	-0.5102476799062078	[5,5]	[4,0]	-6	hSpCas9	positive selection	3013904
4032444	4032467	6	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CCAAAGAGAGAAAATCAAAACGG	PRPF4B	ENSG00000112739	-0.6495735888134002	[3,3]	[1,0]	-8	hSpCas9	positive selection	3081759
4032592	4032615	6	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CTTCTTCTTGATTTATCACGTGG	PRPF4B	ENSG00000112739	-0.28476221479560476	[4,4]	[4,1]	-4	hSpCas9	positive selection	3081760
4032069	4032092	6	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GTAAAAGCAGATCCAAAGAACGG	PRPF4B	ENSG00000112739	-1.1898324563870664	[2,2]	[0,0]	-9	hSpCas9	positive selection	3081761
4037487	4037510	6	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GTAGATCTCCCATTAGAAGGAGG	PRPF4B	ENSG00000112739	0.09673253575478252	[5,5]	[5,2]	1	hSpCas9	positive selection	3081762
4042487	4042510		-	24336571	A375	resistance to PLX after 7 days	CCTCTACATCAAAGTCTTCAAGG	PRPF4B	ENSG00000112739	0.1529499586286699	[6,5]	[6,6]	5	hSpCas9	positive selection	3138011
4042547	4042570		-	24336571	A375	resistance to PLX after 7 days	CCTGAACAATTGCCTGCCTTTGG	PRPF4B	ENSG00000112739	0.25741864916332197	[7,12]	[14,10]	7	hSpCas9	positive selection	3138013
4021443	4021466		-	24336571	A375	resistance to PLX after 7 days	CTGGCTGCTCCCGTAGCGACTGG	PRPF4B	ENSG00000112739	-0.1790933223820551	[6,5]	[5,4]	-5	hSpCas9	positive selection	3138014
4042487	4042510		-	24336571	A375	resistance to PLX after 14 days	CCTCTACATCAAAGTCTTCAAGG	PRPF4B	ENSG00000112739	0.20605655666921796	[5,5]	[2,2]	2	hSpCas9	positive selection	3195804
4042547	4042570		-	24336571	A375	resistance to PLX after 14 days	CCTGAACAATTGCCTGCCTTTGG	PRPF4B	ENSG00000112739	0.46835493390540905	[9,8]	[4,6]	4	hSpCas9	positive selection	3195806
4021443	4021466		-	24336571	A375	resistance to PLX after 14 days	CTGGCTGCTCCCGTAGCGACTGG	PRPF4B	ENSG00000112739	-0.3239879953303716	[5,5]	[1,1]	-4	hSpCas9	positive selection	3195807
4042487	4042510		-	24336571	A375	viability after 7 days	CCTCTACATCAAAGTCTTCAAGG	PRPF4B	ENSG00000112739	-0.7005419101738108	[10]	[6,5]	-7	hSpCas9	negative selection	3253597
4042547	4042570		-	24336571	A375	viability after 7 days	CCTGAACAATTGCCTGCCTTTGG	PRPF4B	ENSG00000112739	-0.02662955201738884	[10]	[7,12]	0	hSpCas9	negative selection	3253599
4021443	4021466		-	24336571	A375	viability after 7 days	CTGGCTGCTCCCGTAGCGACTGG	PRPF4B	ENSG00000112739	-0.38054650859863615	[8]	[6,5]	-5	hSpCas9	negative selection	3253600
4042487	4042510		-	24336571	A375	viability after 14 days	CCTCTACATCAAAGTCTTCAAGG	PRPF4B	ENSG00000112739	-0.7922192971071964	[10]	[5,5]	-7	hSpCas9	negative selection	3311390
4042547	4042570		-	24336571	A375	viability after 14 days	CCTGAACAATTGCCTGCCTTTGG	PRPF4B	ENSG00000112739	-0.15856602185883936	[10]	[9,8]	-2	hSpCas9	negative selection	3311392
4021443	4021466		-	24336571	A375	viability after 14 days	CTGGCTGCTCCCGTAGCGACTGG	PRPF4B	ENSG00000112739	-0.3786757359745927	[8]	[5,5]	-4	hSpCas9	negative selection	3311393
4043824	4043847	6	-	27383988	293T	resistance to West Nile virus (flavivirus)	ACATGTTGCTATCTTCAGCAAGG	PRPF4B	ENSG00000112739	2.5024387092823663	[80,80]	[2,2]	8	hSpCas9	positive selection	3387667
4042487	4042510	6	-	27383988	293T	resistance to West Nile virus (flavivirus)	CCTCTACATCAAAGTCTTCAAGG	PRPF4B	ENSG00000112739	-0.4150991305256606	[203,203]	[0,0]	-3	hSpCas9	positive selection	3387668
4042547	4042570	6	-	27383988	293T	resistance to West Nile virus (flavivirus)	CCTGAACAATTGCCTGCCTTTGG	PRPF4B	ENSG00000112739	-0.7026757206222457	[248,248]	[0,0]	-5	hSpCas9	positive selection	3387669
4032443	4032466	6	+	26780180	HT29	viability (Avana library 4 designs)	CCAAAGAGAGAAAATCAAAACGG	PRPF4B	ENSG00000112739	2.40335943405409	[]	[]	8	hSpCas9	negative selection	3452096
4032592	4032615	6	-	26780180	HT29	viability (Avana library 4 designs)	CTTCTTCTTGATTTATCACGTGG	PRPF4B	ENSG00000112739	1.02830867004247	[]	[]	4	hSpCas9	negative selection	3452097
4032068	4032091	6	+	26780180	HT29	viability (Avana library 4 designs)	GTAAAAGCAGATCCAAAGAACGG	PRPF4B	ENSG00000112739	3.61653087348863	[]	[]	9	hSpCas9	negative selection	3452098
4037486	4037509	6	+	26780180	HT29	viability (Avana library 4 designs)	GTAGATCTCCCATTAGAAGGAGG	PRPF4B	ENSG00000112739	1.60207827983359	[]	[]	6	hSpCas9	negative selection	3452099
4032443	4032466	6	+	26780180	A375	viability (Avana lentiCRISPRv2)	CCAAAGAGAGAAAATCAAAACGG	PRPF4B	ENSG00000112739	-12.1299431164615	[]	[]	-8	hSpCas9	negative selection	3548304
4037486	4037509	6	+	26780180	A375	viability (Avana lentiCRISPRv2)	GTAGATCTCCCATTAGAAGGAGG	PRPF4B	ENSG00000112739	-4.9278671185	[]	[]	-5	hSpCas9	negative selection	3548305
4032068	4032091	6	+	26780180	A375	viability (Avana lentiCRISPRv2)	GTAAAAGCAGATCCAAAGAACGG	PRPF4B	ENSG00000112739	-17.4863802691242	[]	[]	-9	hSpCas9	negative selection	3548306
4032592	4032615	6	-	26780180	A375	viability (Avana lentiCRISPRv2)	CTTCTTCTTGATTTATCACGTGG	PRPF4B	ENSG00000112739	-4.4029662006421	[]	[]	-5	hSpCas9	negative selection	3548307
4032155	4032178	6	+	26780180	A375	viability (Avana lentiCRISPRv2)	CTAGGAGCAAGTCAAAGGAGAGG	PRPF4B	ENSG00000112739	-3.69989092279053	[]	[]	-4	hSpCas9	negative selection	3548308
4040806	4040829	6	+	26780180	A375	viability (Avana lentiCRISPRv2)	AGGCGGTCTCGATCACGCGGTGG	PRPF4B	ENSG00000112739	1.3066717690746	[]	[]	1	hSpCas9	negative selection	3548309
4032443	4032466	6	+	26780180	A375	viability (Avana lentiGuide)	CCAAAGAGAGAAAATCAAAACGG	PRPF4B	ENSG00000112739	0.12932941499257	[]	[]	0	hSpCas9	negative selection	3656963
4037486	4037509	6	+	26780180	A375	viability (Avana lentiGuide)	GTAGATCTCCCATTAGAAGGAGG	PRPF4B	ENSG00000112739	5.45464187043941	[]	[]	5	hSpCas9	negative selection	3656964
4032068	4032091	6	+	26780180	A375	viability (Avana lentiGuide)	GTAAAAGCAGATCCAAAGAACGG	PRPF4B	ENSG00000112739	5.91345769292211	[]	[]	5	hSpCas9	negative selection	3656965
4032592	4032615	6	-	26780180	A375	viability (Avana lentiGuide)	CTTCTTCTTGATTTATCACGTGG	PRPF4B	ENSG00000112739	0.999836853079907	[]	[]	1	hSpCas9	negative selection	3656966
4032155	4032178	6	+	26780180	A375	viability (Avana lentiGuide)	CTAGGAGCAAGTCAAAGGAGAGG	PRPF4B	ENSG00000112739	17.7945071500394	[]	[]	8	hSpCas9	negative selection	3656967
4040806	4040829	6	+	26780180	A375	viability (Avana lentiGuide)	AGGCGGTCTCGATCACGCGGTGG	PRPF4B	ENSG00000112739	3.3529127713252	[]	[]	3	hSpCas9	negative selection	3656968
4032443	4032466	6	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CCAAAGAGAGAAAATCAAAACGG	PRPF4B	ENSG00000112739	-0.7614291909252733	[6]	[5,1]	-8	hSpCas9	positive selection	3765570
4037486	4037509	6	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GTAGATCTCCCATTAGAAGGAGG	PRPF4B	ENSG00000112739	-0.4063504553896588	[7]	[5,5]	-6	hSpCas9	positive selection	3765571
4032068	4032091	6	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GTAAAAGCAGATCCAAAGAACGG	PRPF4B	ENSG00000112739	-1.7171413998428473	[7]	[0,2]	-9	hSpCas9	positive selection	3765572
4032592	4032615	6	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CTTCTTCTTGATTTATCACGTGG	PRPF4B	ENSG00000112739	-0.2434087659930259	[6]	[5,5]	-4	hSpCas9	positive selection	3765573
4032155	4032178	6	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CTAGGAGCAAGTCAAAGGAGAGG	PRPF4B	ENSG00000112739	-0.3556598131616656	[4]	[3,2]	-5	hSpCas9	positive selection	3765574
4040806	4040829	6	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AGGCGGTCTCGATCACGCGGTGG	PRPF4B	ENSG00000112739	-0.4754933791186219	[4]	[3,1]	-6	hSpCas9	positive selection	3765575
4032443	4032466	6	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CCAAAGAGAGAAAATCAAAACGG	PRPF4B	ENSG00000112739	0.09928505191349415	[4]	[3,4]	2	hSpCas9	positive selection	3874177
4037486	4037509	6	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GTAGATCTCCCATTAGAAGGAGG	PRPF4B	ENSG00000112739	-0.1448205490348666	[7]	[5,5]	-2	hSpCas9	positive selection	3874178
4032068	4032091	6	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GTAAAAGCAGATCCAAAGAACGG	PRPF4B	ENSG00000112739	-1.5925121450558561	[5]	[0,0]	-9	hSpCas9	positive selection	3874179
4032592	4032615	6	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CTTCTTCTTGATTTATCACGTGG	PRPF4B	ENSG00000112739	0.22624072322731587	[6]	[6,6]	6	hSpCas9	positive selection	3874180
4032155	4032178	6	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CTAGGAGCAAGTCAAAGGAGAGG	PRPF4B	ENSG00000112739	-0.5065632394071715	[5]	[2,3]	-6	hSpCas9	positive selection	3874181
4040806	4040829	6	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AGGCGGTCTCGATCACGCGGTGG	PRPF4B	ENSG00000112739	-1.3857221013071546	[4]	[1,0]	-9	hSpCas9	positive selection	3874182
4043824	4043847	6	-	26780180	A375	viability	ACATGTTGCTATCTTCAGCAAGG	PRPF4B	ENSG00000112739	2.11072720139931	[]	[]	9	hSpCas9	negative selection	3984633
4043872	4043895	6	-	26780180	A375	viability	ATCGTGTTCTCGTACTGCTCTGG	PRPF4B	ENSG00000112739	0.933592148975731	[]	[]	4	hSpCas9	negative selection	3984634
4042487	4042510	6	-	26780180	A375	viability	CCTCTACATCAAAGTCTTCAAGG	PRPF4B	ENSG00000112739	0.634751756490576	[]	[]	2	hSpCas9	negative selection	3984635
4042547	4042570	6	-	26780180	A375	viability	CCTGAACAATTGCCTGCCTTTGG	PRPF4B	ENSG00000112739	2.16047731066677	[]	[]	9	hSpCas9	negative selection	3984636
4021443	4021466	6	-	26780180	A375	viability	CTGGCTGCTCCCGTAGCGACTGG	PRPF4B	ENSG00000112739	0.875424927243613	[]	[]	3	hSpCas9	negative selection	3984637
4021416	4021439	6	+	26780180	A375	viability	GAAGTTCAAGATGGCCGCCGCGG	PRPF4B	ENSG00000112739	0.924175951136933	[]	[]	4	hSpCas9	negative selection	3984638
4043824	4043847	6	-	26780180	HT29	viability (GeCKOv2 library)	ACATGTTGCTATCTTCAGCAAGG	PRPF4B	ENSG00000112739	1.98911413264875	[]	[]	9	hSpCas9	negative selection	4092599
4043872	4043895	6	-	26780180	HT29	viability (GeCKOv2 library)	ATCGTGTTCTCGTACTGCTCTGG	PRPF4B	ENSG00000112739	1.0911411009582	[]	[]	5	hSpCas9	negative selection	4092600
4042487	4042510	6	-	26780180	HT29	viability (GeCKOv2 library)	CCTCTACATCAAAGTCTTCAAGG	PRPF4B	ENSG00000112739	0.353726140800837	[]	[]	1	hSpCas9	negative selection	4092601
4042547	4042570	6	-	26780180	HT29	viability (GeCKOv2 library)	CCTGAACAATTGCCTGCCTTTGG	PRPF4B	ENSG00000112739	1.56508125894557	[]	[]	8	hSpCas9	negative selection	4092602
4021443	4021466	6	-	26780180	HT29	viability (GeCKOv2 library)	CTGGCTGCTCCCGTAGCGACTGG	PRPF4B	ENSG00000112739	1.37186640353183	[]	[]	7	hSpCas9	negative selection	4092603
4021416	4021439	6	+	26780180	HT29	viability (GeCKOv2 library)	GAAGTTCAAGATGGCCGCCGCGG	PRPF4B	ENSG00000112739	0.54569804587042	[]	[]	1	hSpCas9	negative selection	4092604
4042487	4042510	6	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CCTCTACATCAAAGTCTTCAAGG	PRPF4B	ENSG00000112739	0.06470122181453819	[1]	[0,1]	1	hSpCas9	positive selection	4163189
4042547	4042570	6	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CCTGAACAATTGCCTGCCTTTGG	PRPF4B	ENSG00000112739	0.4720384872265003	[3]	[4,2]	8	hSpCas9	positive selection	4163191
4021443	4021466	6	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CTGGCTGCTCCCGTAGCGACTGG	PRPF4B	ENSG00000112739	0.3570833918449669	[2]	[3,0]	8	hSpCas9	positive selection	4163192
4042487	4042510	6	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CCTCTACATCAAAGTCTTCAAGG	PRPF4B	ENSG00000112739	0.05000660874329893	[2]	[2,0,0,0]	0	hSpCas9	positive selection	4227211
4042547	4042570	6	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CCTGAACAATTGCCTGCCTTTGG	PRPF4B	ENSG00000112739	0.1259966161143973	[3]	[2,0,1,1]	1	hSpCas9	positive selection	4227213
4021443	4021466	6	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CTGGCTGCTCCCGTAGCGACTGG	PRPF4B	ENSG00000112739	1.1717975264124423	[2]	[2,1,0,3]	8	hSpCas9	positive selection	4227214
4021443	4021466	6	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CTGGCTGCTCCCGTAGCGACTGG	PRPF4B	ENSG00000112739	-0.062406632473707396	[3]	[3,1]	-1	hSpCas9	positive selection	4292374
4043872	4043895	6	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ATCGTGTTCTCGTACTGCTCTGG	PRPF4B	ENSG00000112739	0.11560569855277297	[3]	[3,2]	2	hSpCas9	positive selection	4292375
4021416	4021439	6	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GAAGTTCAAGATGGCCGCCGCGG	PRPF4B	ENSG00000112739	0.37898388433356	[2]	[3,1]	7	hSpCas9	positive selection	4292376
4043824	4043847	6	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ACATGTTGCTATCTTCAGCAAGG	PRPF4B	ENSG00000112739	-0.3055745988082041	[3]	[2,1]	-6	hSpCas9	positive selection	4356633
4042487	4042510	6	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCTCTACATCAAAGTCTTCAAGG	PRPF4B	ENSG00000112739	-0.0034933858764835055	[2]	[3,1]	0	hSpCas9	positive selection	4356634
4042547	4042570	6	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCTGAACAATTGCCTGCCTTTGG	PRPF4B	ENSG00000112739	-0.21751567705344466	[4]	[2,2]	-4	hSpCas9	positive selection	4356635
4032241	4032263	6	-	27760321	OCIAML3	viability	GAGATCGCCTTCTAAGGGTAGG	PRPF4B	ENSG00000112739	-1.771650266531339	[450,429]	[120,74]	-9	hSpCas9	negative selection	4430891
4032553	4032575	6	-	27760321	OCIAML3	viability	TTCTTTTAGGACTACGACCAGG	PRPF4B	ENSG00000112739	0.5468241053837337	[174,195]	[164,276]	6	hSpCas9	negative selection	4430892
4037514	4037536	6	+	27760321	OCIAML3	viability	TTCCCCACTCAGACGTAGCAGG	PRPF4B	ENSG00000112739	-0.10188090290775775	[661,579]	[359,570]	-1	hSpCas9	negative selection	4430893
4040787	4040809	6	+	27760321	OCIAML3	viability	GAGCAGATCACGCTTGCGAAGG	PRPF4B	ENSG00000112739	0.0016520694032948202	[662,540]	[402,554]	0	hSpCas9	negative selection	4430894
4040820	4040842	6	+	27760321	OCIAML3	viability	ACGCGGTGGTCGTAGACGAAGG	PRPF4B	ENSG00000112739	-0.6859342256075837	[613,517]	[284,259]	-6	hSpCas9	negative selection	4430895
4032241	4032263	6	-	27760321	OCIAML2	viability	GAGATCGCCTTCTAAGGGTAGG	PRPF4B	ENSG00000112739	-1.5813247570118358	[450,429]	[104,137]	-8	hSpCas9	negative selection	4514354
4032553	4032575	6	-	27760321	OCIAML2	viability	TTCTTTTAGGACTACGACCAGG	PRPF4B	ENSG00000112739	-0.5418744509456068	[174,195]	[77,137]	-6	hSpCas9	negative selection	4514355
4037514	4037536	6	+	27760321	OCIAML2	viability	TTCCCCACTCAGACGTAGCAGG	PRPF4B	ENSG00000112739	-0.09666646927112033	[661,579]	[413,540]	-1	hSpCas9	negative selection	4514356
4040787	4040809	6	+	27760321	OCIAML2	viability	GAGCAGATCACGCTTGCGAAGG	PRPF4B	ENSG00000112739	-0.03619364972821054	[662,540]	[393,575]	0	hSpCas9	negative selection	4514357
4040820	4040842	6	+	27760321	OCIAML2	viability	ACGCGGTGGTCGTAGACGAAGG	PRPF4B	ENSG00000112739	-0.9053294684026525	[613,517]	[202,296]	-7	hSpCas9	negative selection	4514358
4032241	4032263	6	-	27760321	MV411	viability	GAGATCGCCTTCTAAGGGTAGG	PRPF4B	ENSG00000112739	-0.7095133358854246	[450,429]	[175,180]	-5	hSpCas9	negative selection	4597817
4032553	4032575	6	-	27760321	MV411	viability	TTCTTTTAGGACTACGACCAGG	PRPF4B	ENSG00000112739	0.4595100523304688	[174,195]	[0,422]	3	hSpCas9	negative selection	4597818
4037514	4037536	6	+	27760321	MV411	viability	TTCCCCACTCAGACGTAGCAGG	PRPF4B	ENSG00000112739	-0.07499086645134029	[661,579]	[400,368]	0	hSpCas9	negative selection	4597819
4040787	4040809	6	+	27760321	MV411	viability	GAGCAGATCACGCTTGCGAAGG	PRPF4B	ENSG00000112739	-0.887722507201647	[662,540]	[243,167]	-5	hSpCas9	negative selection	4597820
4040820	4040842	6	+	27760321	MV411	viability	ACGCGGTGGTCGTAGACGAAGG	PRPF4B	ENSG00000112739	-1.4105523913525886	[613,517]	[119,169]	-7	hSpCas9	negative selection	4597821
4032241	4032263	6	-	27760321	HL60	viability	GAGATCGCCTTCTAAGGGTAGG	PRPF4B	ENSG00000112739	-1.0294594174983724	[450,429]	[176,175]	-7	hSpCas9	negative selection	4681280
4032553	4032575	6	-	27760321	HL60	viability	TTCTTTTAGGACTACGACCAGG	PRPF4B	ENSG00000112739	0.9086129463051484	[174,195]	[326,243]	8	hSpCas9	negative selection	4681281
4037514	4037536	6	+	27760321	HL60	viability	TTCCCCACTCAGACGTAGCAGG	PRPF4B	ENSG00000112739	0.08686174180464212	[661,579]	[590,480]	1	hSpCas9	negative selection	4681282
4040787	4040809	6	+	27760321	HL60	viability	GAGCAGATCACGCTTGCGAAGG	PRPF4B	ENSG00000112739	0.12981178770012497	[662,540]	[430,645]	1	hSpCas9	negative selection	4681283
4040820	4040842	6	+	27760321	HL60	viability	ACGCGGTGGTCGTAGACGAAGG	PRPF4B	ENSG00000112739	-0.654715697925987	[613,517]	[262,323]	-6	hSpCas9	negative selection	4681284
4032241	4032263	6	-	27760321	HT1080	viability	GAGATCGCCTTCTAAGGGTAGG	PRPF4B	ENSG00000112739	-6.690476552280244	[429,335]	[0,1]	-9	hSpCas9	negative selection	4764743
4032553	4032575	6	-	27760321	HT1080	viability	TTCTTTTAGGACTACGACCAGG	PRPF4B	ENSG00000112739	-4.0011017582351895	[195,152]	[0,7]	-8	hSpCas9	negative selection	4764744
4037514	4037536	6	+	27760321	HT1080	viability	TTCCCCACTCAGACGTAGCAGG	PRPF4B	ENSG00000112739	-1.8028262616302682	[579,452]	[68,47]	-6	hSpCas9	negative selection	4764745
4040787	4040809	6	+	27760321	HT1080	viability	GAGCAGATCACGCTTGCGAAGG	PRPF4B	ENSG00000112739	-2.9635937475779133	[540,421]	[36,10]	-7	hSpCas9	negative selection	4764746
4040820	4040842	6	+	27760321	HT1080	viability	ACGCGGTGGTCGTAGACGAAGG	PRPF4B	ENSG00000112739	-4.215500487160069	[517,403]	[17,0]	-8	hSpCas9	negative selection	4764747
4032241	4032263	6	-	27760321	HT29	viability after 7 days	GAGATCGCCTTCTAAGGGTAGG	PRPF4B	ENSG00000112739	-0.9627819461680096	[429,335]	[159,222,357]	-8	hSpCas9	negative selection	4848206
4032553	4032575	6	-	27760321	HT29	viability after 7 days	TTCTTTTAGGACTACGACCAGG	PRPF4B	ENSG00000112739	-0.3546136367272841	[195,152]	[210,137,181]	-5	hSpCas9	negative selection	4848207
4037514	4037536	6	+	27760321	HT29	viability after 7 days	TTCCCCACTCAGACGTAGCAGG	PRPF4B	ENSG00000112739	-0.3725340340558011	[579,452]	[389,565,562]	-5	hSpCas9	negative selection	4848208
4040787	4040809	6	+	27760321	HT29	viability after 7 days	GAGCAGATCACGCTTGCGAAGG	PRPF4B	ENSG00000112739	0.18861261779324556	[540,421]	[789,677,660]	3	hSpCas9	negative selection	4848209
4040820	4040842	6	+	27760321	HT29	viability after 7 days	ACGCGGTGGTCGTAGACGAAGG	PRPF4B	ENSG00000112739	-0.739676667379122	[517,403]	[262,362,422]	-8	hSpCas9	negative selection	4848210
4032241	4032263	6	-	27760321	HT29	viability after 25 days	GAGATCGCCTTCTAAGGGTAGG	PRPF4B	ENSG00000112739	-1.2323378202659538	[429,335]	[90,292,179]	-7	hSpCas9	negative selection	4931669
4032553	4032575	6	-	27760321	HT29	viability after 25 days	TTCTTTTAGGACTACGACCAGG	PRPF4B	ENSG00000112739	-0.46476712784790264	[195,152]	[222,80,121]	-4	hSpCas9	negative selection	4931670
4037514	4037536	6	+	27760321	HT29	viability after 25 days	TTCCCCACTCAGACGTAGCAGG	PRPF4B	ENSG00000112739	-0.6150201338949757	[579,452]	[244,391,543]	-5	hSpCas9	negative selection	4931671
4040787	4040809	6	+	27760321	HT29	viability after 25 days	GAGCAGATCACGCTTGCGAAGG	PRPF4B	ENSG00000112739	-0.7309943397695142	[540,421]	[395,339,244]	-6	hSpCas9	negative selection	4931672
4040820	4040842	6	+	27760321	HT29	viability after 25 days	ACGCGGTGGTCGTAGACGAAGG	PRPF4B	ENSG00000112739	-0.8861714541370515	[517,403]	[168,312,390]	-6	hSpCas9	negative selection	4931673
4032241	4032263	6	-	27760321	HT29	viability after 22 days	GAGATCGCCTTCTAAGGGTAGG	PRPF4B	ENSG00000112739	-1.9877539447027746	[429,335]	[40,166,128]	-8	hSpCas9	negative selection	5015132
4032553	4032575	6	-	27760321	HT29	viability after 22 days	TTCTTTTAGGACTACGACCAGG	PRPF4B	ENSG00000112739	0.07067122955670024	[195,152]	[259,190,182]	0	hSpCas9	negative selection	5015133
4037514	4037536	6	+	27760321	HT29	viability after 22 days	TTCCCCACTCAGACGTAGCAGG	PRPF4B	ENSG00000112739	-0.9083287928445936	[579,452]	[213,346,396]	-6	hSpCas9	negative selection	5015134
4040787	4040809	6	+	27760321	HT29	viability after 22 days	GAGCAGATCACGCTTGCGAAGG	PRPF4B	ENSG00000112739	-0.4073042756461374	[540,421]	[414,448,394]	-4	hSpCas9	negative selection	5015135
4040820	4040842	6	+	27760321	HT29	viability after 22 days	ACGCGGTGGTCGTAGACGAAGG	PRPF4B	ENSG00000112739	-0.28667912114841176	[517,403]	[250,380,685]	-3	hSpCas9	negative selection	5015136
4032241	4032263	6	-	27760321	HT29	viability after 19 days	GAGATCGCCTTCTAAGGGTAGG	PRPF4B	ENSG00000112739	-1.2640188366540681	[429,335]	[146,337,62]	-7	hSpCas9	negative selection	5098595
4032553	4032575	6	-	27760321	HT29	viability after 19 days	TTCTTTTAGGACTACGACCAGG	PRPF4B	ENSG00000112739	0.3908385639467038	[195,152]	[116,291,356]	4	hSpCas9	negative selection	5098596
4037514	4037536	6	+	27760321	HT29	viability after 19 days	TTCCCCACTCAGACGTAGCAGG	PRPF4B	ENSG00000112739	-1.3253761146879035	[579,452]	[340,273,107]	-7	hSpCas9	negative selection	5098597
4040787	4040809	6	+	27760321	HT29	viability after 19 days	GAGCAGATCACGCTTGCGAAGG	PRPF4B	ENSG00000112739	-0.4786103776380924	[540,421]	[360,405,413]	-4	hSpCas9	negative selection	5098598
4040820	4040842	6	+	27760321	HT29	viability after 19 days	ACGCGGTGGTCGTAGACGAAGG	PRPF4B	ENSG00000112739	-1.0785482294430504	[517,403]	[277,204,267]	-6	hSpCas9	negative selection	5098599
4032241	4032263	6	-	27760321	HT29	viability after 16 days	GAGATCGCCTTCTAAGGGTAGG	PRPF4B	ENSG00000112739	-0.44862080589221565	[429,335]	[343,267,333]	-4	hSpCas9	negative selection	5182058
4032553	4032575	6	-	27760321	HT29	viability after 16 days	TTCTTTTAGGACTACGACCAGG	PRPF4B	ENSG00000112739	-0.3793188296035681	[195,152]	[301,96,66]	-4	hSpCas9	negative selection	5182059
4037514	4037536	6	+	27760321	HT29	viability after 16 days	TTCCCCACTCAGACGTAGCAGG	PRPF4B	ENSG00000112739	-1.1033058148678614	[579,452]	[376,195,245]	-7	hSpCas9	negative selection	5182060
4040787	4040809	6	+	27760321	HT29	viability after 16 days	GAGCAGATCACGCTTGCGAAGG	PRPF4B	ENSG00000112739	-0.47818555463351137	[540,421]	[326,364,462]	-5	hSpCas9	negative selection	5182061
4040820	4040842	6	+	27760321	HT29	viability after 16 days	ACGCGGTGGTCGTAGACGAAGG	PRPF4B	ENSG00000112739	-0.402253174829409	[517,403]	[443,304,428]	-4	hSpCas9	negative selection	5182062
4032241	4032263	6	-	27760321	HT29	viability after 13 days	GAGATCGCCTTCTAAGGGTAGG	PRPF4B	ENSG00000112739	-1.5097686579301277	[429,335]	[44,175,241]	-8	hSpCas9	negative selection	5265521
4032553	4032575	6	-	27760321	HT29	viability after 13 days	TTCTTTTAGGACTACGACCAGG	PRPF4B	ENSG00000112739	-0.8830147315656891	[195,152]	[142,140,48]	-7	hSpCas9	negative selection	5265522
4037514	4037536	6	+	27760321	HT29	viability after 13 days	TTCCCCACTCAGACGTAGCAGG	PRPF4B	ENSG00000112739	-0.6293545640897705	[579,452]	[425,263,466]	-6	hSpCas9	negative selection	5265523
4040787	4040809	6	+	27760321	HT29	viability after 13 days	GAGCAGATCACGCTTGCGAAGG	PRPF4B	ENSG00000112739	-0.18323741107120026	[540,421]	[463,522,488]	-2	hSpCas9	negative selection	5265524
4040820	4040842	6	+	27760321	HT29	viability after 13 days	ACGCGGTGGTCGTAGACGAAGG	PRPF4B	ENSG00000112739	-0.759798053357134	[517,403]	[386,324,239]	-7	hSpCas9	negative selection	5265525
4032241	4032263	6	-	27760321	HT29	viability after 10 days	GAGATCGCCTTCTAAGGGTAGG	PRPF4B	ENSG00000112739	-1.101877700092502	[429,335]	[241,125,295]	-8	hSpCas9	negative selection	5348984
4032553	4032575	6	-	27760321	HT29	viability after 10 days	TTCTTTTAGGACTACGACCAGG	PRPF4B	ENSG00000112739	-1.6623147615159832	[195,152]	[39,111,55]	-8	hSpCas9	negative selection	5348985
4037514	4037536	6	+	27760321	HT29	viability after 10 days	TTCCCCACTCAGACGTAGCAGG	PRPF4B	ENSG00000112739	-0.5342506020075654	[579,452]	[437,510,389]	-6	hSpCas9	negative selection	5348986
4040787	4040809	6	+	27760321	HT29	viability after 10 days	GAGCAGATCACGCTTGCGAAGG	PRPF4B	ENSG00000112739	-0.17803198849708635	[540,421]	[455,704,439]	-2	hSpCas9	negative selection	5348987
4040820	4040842	6	+	27760321	HT29	viability after 10 days	ACGCGGTGGTCGTAGACGAAGG	PRPF4B	ENSG00000112739	-0.6861094073458381	[517,403]	[409,351,311]	-7	hSpCas9	negative selection	5348988
4032241	4032263	6	-	27760321	MOLM13	viability	GAGATCGCCTTCTAAGGGTAGG	PRPF4B	ENSG00000112739	0.5610674248768782	[450,429]	[317,408]	4	hSpCas9	negative selection	5432447
4032553	4032575	6	-	27760321	MOLM13	viability	TTCTTTTAGGACTACGACCAGG	PRPF4B	ENSG00000112739	0.8404477312254359	[174,195]	[297,95]	6	hSpCas9	negative selection	5432448
4037514	4037536	6	+	27760321	MOLM13	viability	TTCCCCACTCAGACGTAGCAGG	PRPF4B	ENSG00000112739	0.4007578925669053	[661,579]	[379,530]	2	hSpCas9	negative selection	5432449
4040787	4040809	6	+	27760321	MOLM13	viability	GAGCAGATCACGCTTGCGAAGG	PRPF4B	ENSG00000112739	-0.2385360552554185	[662,540]	[98,445]	-2	hSpCas9	negative selection	5432450
4040820	4040842	6	+	27760321	MOLM13	viability	ACGCGGTGGTCGTAGACGAAGG	PRPF4B	ENSG00000112739	0.06878629560045924	[613,517]	[478,209]	0	hSpCas9	negative selection	5432451
4021835	4021858	6	+	27661255	K562	viability	GTTGGGGACACGAGGGTCAGTGG	PRPF4B	ENSG00000112739	0.16084054389945313	[789,1065]	[840,809]	5	dCas9-KRAB	negative selection	5504411
4021443	4021466	6	-	27260156	BXPC3	viability	CTGGCTGCTCCCGTAGCGACTGG	PRPF4B	ENSG00000112739	-0.7278535208327024	[627]	[378,352,465,389]	-9	hSpCas9	negative selection	5564834
4043872	4043895	6	-	27260156	BXPC3	viability	ATCGTGTTCTCGTACTGCTCTGG	PRPF4B	ENSG00000112739	-0.27153592978966656	[864]	[575,581,1040,837]	-6	hSpCas9	negative selection	5564835
4021416	4021439	6	+	27260156	BXPC3	viability	GAAGTTCAAGATGGCCGCCGCGG	PRPF4B	ENSG00000112739	0.12581679914370236	[261]	[214,321,304,367]	2	hSpCas9	negative selection	5564836
4043824	4043847	6	-	27260156	BXPC3	viability	ACATGTTGCTATCTTCAGCAAGG	PRPF4B	ENSG00000112739	-1.0446524111593076	[533]	[282,251,303,237]	-9	hSpCas9	negative selection	5629093
4042487	4042510	6	-	27260156	BXPC3	viability	CCTCTACATCAAAGTCTTCAAGG	PRPF4B	ENSG00000112739	-0.17151975017165935	[422]	[310,443,397,424]	-4	hSpCas9	negative selection	5629094
4042547	4042570	6	-	27260156	BXPC3	viability	CCTGAACAATTGCCTGCCTTTGG	PRPF4B	ENSG00000112739	-0.5802510301380847	[1004]	[572,647,766,855]	-8	hSpCas9	negative selection	5629095
4021443	4021466	6	-	27260156	A673	viability	CTGGCTGCTCCCGTAGCGACTGG	PRPF4B	ENSG00000112739	-0.4857191920160868	[627]	[639,560,528,427]	-8	hSpCas9	negative selection	5686085
4043872	4043895	6	-	27260156	A673	viability	ATCGTGTTCTCGTACTGCTCTGG	PRPF4B	ENSG00000112739	-0.20621598882297354	[864]	[945,932,904,814]	-5	hSpCas9	negative selection	5686086
4021416	4021439	6	+	27260156	A673	viability	GAAGTTCAAGATGGCCGCCGCGG	PRPF4B	ENSG00000112739	-0.1006424673653945	[261]	[254,259,313,342]	-3	hSpCas9	negative selection	5686087
4043824	4043847	6	-	27260156	A673	viability	ACATGTTGCTATCTTCAGCAAGG	PRPF4B	ENSG00000112739	-0.7682771808151846	[533]	[358,278,439,429]	-9	hSpCas9	negative selection	5750344
4042487	4042510	6	-	27260156	A673	viability	CCTCTACATCAAAGTCTTCAAGG	PRPF4B	ENSG00000112739	-0.2022567262136232	[422]	[549,401,473,346]	-5	hSpCas9	negative selection	5750345
4042547	4042570	6	-	27260156	A673	viability	CCTGAACAATTGCCTGCCTTTGG	PRPF4B	ENSG00000112739	-0.6131439429135599	[1004]	[1043,734,669,733]	-9	hSpCas9	negative selection	5750346
4021443	4021466	6	-	27260156	A375	viability	CTGGCTGCTCCCGTAGCGACTGG	PRPF4B	ENSG00000112739	-0.49872896661563126	[627]	[752,323,424,543]	-6	hSpCas9	negative selection	5807336
4043872	4043895	6	-	27260156	A375	viability	ATCGTGTTCTCGTACTGCTCTGG	PRPF4B	ENSG00000112739	-0.30129891005688014	[864]	[722,1063,761,766]	-4	hSpCas9	negative selection	5807337
4021416	4021439	6	+	27260156	A375	viability	GAAGTTCAAGATGGCCGCCGCGG	PRPF4B	ENSG00000112739	0.423616344472952	[261]	[547,418,325,355]	6	hSpCas9	negative selection	5807338
4043824	4043847	6	-	27260156	A375	viability	ACATGTTGCTATCTTCAGCAAGG	PRPF4B	ENSG00000112739	-1.3723764779494365	[533]	[171,402,235,180]	-9	hSpCas9	negative selection	5871595
4042487	4042510	6	-	27260156	A375	viability	CCTCTACATCAAAGTCTTCAAGG	PRPF4B	ENSG00000112739	0.08471428242490356	[422]	[481,809,250,582]	1	hSpCas9	negative selection	5871596
4042547	4042570	6	-	27260156	A375	viability	CCTGAACAATTGCCTGCCTTTGG	PRPF4B	ENSG00000112739	-0.09121727088951581	[1004]	[1004,1208,1567,685]	-1	hSpCas9	negative selection	5871597
4021443	4021466	6	-	27260156	COLO741	viability	CTGGCTGCTCCCGTAGCGACTGG	PRPF4B	ENSG00000112739	-0.2932523822009522	[627]	[837,469,668]	-6	hSpCas9	negative selection	5928587
4043872	4043895	6	-	27260156	COLO741	viability	ATCGTGTTCTCGTACTGCTCTGG	PRPF4B	ENSG00000112739	-0.43429797962351774	[864]	[682,970,788]	-7	hSpCas9	negative selection	5928588
4021416	4021439	6	+	27260156	COLO741	viability	GAAGTTCAAGATGGCCGCCGCGG	PRPF4B	ENSG00000112739	0.1757100417492642	[261]	[460,351,330]	4	hSpCas9	negative selection	5928589
4043824	4043847	6	-	27260156	COLO741	viability	ACATGTTGCTATCTTCAGCAAGG	PRPF4B	ENSG00000112739	-0.6720684478504128	[533]	[491,452,349]	-8	hSpCas9	negative selection	5992846
4042487	4042510	6	-	27260156	COLO741	viability	CCTCTACATCAAAGTCTTCAAGG	PRPF4B	ENSG00000112739	0.291087035336851	[422]	[737,773,489]	6	hSpCas9	negative selection	5992847
4042547	4042570	6	-	27260156	COLO741	viability	CCTGAACAATTGCCTGCCTTTGG	PRPF4B	ENSG00000112739	-0.6010732454082689	[1004]	[921,844,781]	-8	hSpCas9	negative selection	5992848
4021443	4021466	6	-	27260156	CAL120	viability	CTGGCTGCTCCCGTAGCGACTGG	PRPF4B	ENSG00000112739	-0.03808230732368756	[627]	[785,807,693]	0	hSpCas9	negative selection	6049838
4043872	4043895	6	-	27260156	CAL120	viability	ATCGTGTTCTCGTACTGCTCTGG	PRPF4B	ENSG00000112739	-0.27353495242458514	[864]	[1075,619,1000]	-4	hSpCas9	negative selection	6049839
4021416	4021439	6	+	27260156	CAL120	viability	GAAGTTCAAGATGGCCGCCGCGG	PRPF4B	ENSG00000112739	-0.26037135634546194	[261]	[281,266,268]	-4	hSpCas9	negative selection	6049840
4043824	4043847	6	-	27260156	CAL120	viability	ACATGTTGCTATCTTCAGCAAGG	PRPF4B	ENSG00000112739	-1.0113608542171018	[533]	[197,329,438]	-8	hSpCas9	negative selection	6114097
4042487	4042510	6	-	27260156	CAL120	viability	CCTCTACATCAAAGTCTTCAAGG	PRPF4B	ENSG00000112739	0.5519067660737687	[422]	[670,936,692]	7	hSpCas9	negative selection	6114098
4042547	4042570	6	-	27260156	CAL120	viability	CCTGAACAATTGCCTGCCTTTGG	PRPF4B	ENSG00000112739	-0.20097130170789335	[1004]	[1200,1018,1060]	-3	hSpCas9	negative selection	6114099
4021443	4021466	6	-	27260156	CADOES1	viability	CTGGCTGCTCCCGTAGCGACTGG	PRPF4B	ENSG00000112739	-0.3625552132614102	[627]	[462,394,427,533]	-6	hSpCas9	negative selection	6171089
4043872	4043895	6	-	27260156	CADOES1	viability	ATCGTGTTCTCGTACTGCTCTGG	PRPF4B	ENSG00000112739	-0.29880859073884936	[864]	[794,521,627,670]	-5	hSpCas9	negative selection	6171090
4021416	4021439	6	+	27260156	CADOES1	viability	GAAGTTCAAGATGGCCGCCGCGG	PRPF4B	ENSG00000112739	-0.29827567711128045	[261]	[288,173,140,187]	-5	hSpCas9	negative selection	6171091
4043824	4043847	6	-	27260156	CADOES1	viability	ACATGTTGCTATCTTCAGCAAGG	PRPF4B	ENSG00000112739	-1.288147162935394	[533]	[259,151,126,276]	-9	hSpCas9	negative selection	6235348
4042487	4042510	6	-	27260156	CADOES1	viability	CCTCTACATCAAAGTCTTCAAGG	PRPF4B	ENSG00000112739	0.09033434809059845	[422]	[292,353,621,405]	1	hSpCas9	negative selection	6235349
4042547	4042570	6	-	27260156	CADOES1	viability	CCTGAACAATTGCCTGCCTTTGG	PRPF4B	ENSG00000112739	-0.33522280513546454	[1004]	[858,683,735,681]	-5	hSpCas9	negative selection	6235350
4021443	4021466	6	-	27260156	EWS502	viability	CTGGCTGCTCCCGTAGCGACTGG	PRPF4B	ENSG00000112739	-0.6101361503365227	[627]	[343,500,458,446]	-7	hSpCas9	negative selection	6292340
4043872	4043895	6	-	27260156	EWS502	viability	ATCGTGTTCTCGTACTGCTCTGG	PRPF4B	ENSG00000112739	-0.21402055470443815	[864]	[832,736,799,782]	-4	hSpCas9	negative selection	6292341
4021416	4021439	6	+	27260156	EWS502	viability	GAAGTTCAAGATGGCCGCCGCGG	PRPF4B	ENSG00000112739	0.3285707744356361	[261]	[462,289,279,346]	6	hSpCas9	negative selection	6292342
4043824	4043847	6	-	27260156	EWS502	viability	ACATGTTGCTATCTTCAGCAAGG	PRPF4B	ENSG00000112739	-1.7726428669616903	[533]	[117,93,277,182]	-9	hSpCas9	negative selection	6356599
4042487	4042510	6	-	27260156	EWS502	viability	CCTCTACATCAAAGTCTTCAAGG	PRPF4B	ENSG00000112739	0.15649024969539282	[422]	[419,381,548,671]	2	hSpCas9	negative selection	6356600
4042547	4042570	6	-	27260156	EWS502	viability	CCTGAACAATTGCCTGCCTTTGG	PRPF4B	ENSG00000112739	-0.5585348173092709	[1004]	[669,764,656,805]	-7	hSpCas9	negative selection	6356601
4021443	4021466	6	-	27260156	EW8	viability	CTGGCTGCTCCCGTAGCGACTGG	PRPF4B	ENSG00000112739	-0.4462009418076771	[627]	[462,313,329,402]	-7	hSpCas9	negative selection	6413591
4043872	4043895	6	-	27260156	EW8	viability	ATCGTGTTCTCGTACTGCTCTGG	PRPF4B	ENSG00000112739	0.1860413640172559	[864]	[1016,795,727,682]	3	hSpCas9	negative selection	6413592
4021416	4021439	6	+	27260156	EW8	viability	GAAGTTCAAGATGGCCGCCGCGG	PRPF4B	ENSG00000112739	0.12441751862833539	[261]	[234,324,154,223]	2	hSpCas9	negative selection	6413593
4043824	4043847	6	-	27260156	EW8	viability	ACATGTTGCTATCTTCAGCAAGG	PRPF4B	ENSG00000112739	-0.8931443849639701	[533]	[249,236,192,259]	-9	hSpCas9	negative selection	6477850
4042487	4042510	6	-	27260156	EW8	viability	CCTCTACATCAAAGTCTTCAAGG	PRPF4B	ENSG00000112739	0.022568377077920004	[422]	[336,249,400,392]	0	hSpCas9	negative selection	6477851
4042547	4042570	6	-	27260156	EW8	viability	CCTGAACAATTGCCTGCCTTTGG	PRPF4B	ENSG00000112739	-0.5457491208839198	[1004]	[602,423,510,703]	-7	hSpCas9	negative selection	6477852
4021443	4021466	6	-	27260156	CORL105	viability	CTGGCTGCTCCCGTAGCGACTGG	PRPF4B	ENSG00000112739	-0.14622172983911963	[627]	[761,452,719,737]	-3	hSpCas9	negative selection	6534842
4043872	4043895	6	-	27260156	CORL105	viability	ATCGTGTTCTCGTACTGCTCTGG	PRPF4B	ENSG00000112739	-0.18282176339944134	[864]	[1090,819,948,725]	-3	hSpCas9	negative selection	6534843
4021416	4021439	6	+	27260156	CORL105	viability	GAAGTTCAAGATGGCCGCCGCGG	PRPF4B	ENSG00000112739	0.16694637568782478	[261]	[423,304,425,238]	3	hSpCas9	negative selection	6534844
4043824	4043847	6	-	27260156	CORL105	viability	ACATGTTGCTATCTTCAGCAAGG	PRPF4B	ENSG00000112739	-0.9898347418459491	[533]	[311,261,503,211]	-9	hSpCas9	negative selection	6599101
4042487	4042510	6	-	27260156	CORL105	viability	CCTCTACATCAAAGTCTTCAAGG	PRPF4B	ENSG00000112739	-0.10521974255224356	[422]	[456,454,664,296]	-2	hSpCas9	negative selection	6599102
4042547	4042570	6	-	27260156	CORL105	viability	CCTGAACAATTGCCTGCCTTTGG	PRPF4B	ENSG00000112739	-0.5830206868112319	[1004]	[634,1048,700,732]	-8	hSpCas9	negative selection	6599103
4021443	4021466	6	-	27260156	HS294T	viability	CTGGCTGCTCCCGTAGCGACTGG	PRPF4B	ENSG00000112739	-0.6298710053910053	[627]	[96,122,182,245]	-7	hSpCas9	negative selection	6656093
4043872	4043895	6	-	27260156	HS294T	viability	ATCGTGTTCTCGTACTGCTCTGG	PRPF4B	ENSG00000112739	0.27870941770052526	[864]	[254,481,328,599]	4	hSpCas9	negative selection	6656094
4021416	4021439	6	+	27260156	HS294T	viability	GAAGTTCAAGATGGCCGCCGCGG	PRPF4B	ENSG00000112739	0.49216053561512585	[261]	[76,193,80,237]	6	hSpCas9	negative selection	6656095
4043824	4043847	6	-	27260156	HS294T	viability	ACATGTTGCTATCTTCAGCAAGG	PRPF4B	ENSG00000112739	-1.3777867329834883	[533]	[63,68,113,70]	-9	hSpCas9	negative selection	6720352
4042487	4042510	6	-	27260156	HS294T	viability	CCTCTACATCAAAGTCTTCAAGG	PRPF4B	ENSG00000112739	-0.19155481376022535	[422]	[98,176,143,157]	-3	hSpCas9	negative selection	6720353
4042547	4042570	6	-	27260156	HS294T	viability	CCTGAACAATTGCCTGCCTTTGG	PRPF4B	ENSG00000112739	-0.2548784344123374	[1004]	[372,285,294,347]	-4	hSpCas9	negative selection	6720354
4021443	4021466	6	-	27260156	HCC44	viability	CTGGCTGCTCCCGTAGCGACTGG	PRPF4B	ENSG00000112739	-0.5403868689925632	[627]	[364,601,429,513]	-7	hSpCas9	negative selection	6777344
4043872	4043895	6	-	27260156	HCC44	viability	ATCGTGTTCTCGTACTGCTCTGG	PRPF4B	ENSG00000112739	-0.11441313221109017	[864]	[738,700,1258,980]	-2	hSpCas9	negative selection	6777345
4021416	4021439	6	+	27260156	HCC44	viability	GAAGTTCAAGATGGCCGCCGCGG	PRPF4B	ENSG00000112739	-0.012010597123365496	[261]	[530,175,362,157]	0	hSpCas9	negative selection	6777346
4043824	4043847	6	-	27260156	HCC44	viability	ACATGTTGCTATCTTCAGCAAGG	PRPF4B	ENSG00000112739	-1.168881425375802	[533]	[456,147,123,349]	-9	hSpCas9	negative selection	6841603
4042487	4042510	6	-	27260156	HCC44	viability	CCTCTACATCAAAGTCTTCAAGG	PRPF4B	ENSG00000112739	0.39410785792255887	[422]	[739,419,802,616]	6	hSpCas9	negative selection	6841604
4042547	4042570	6	-	27260156	HCC44	viability	CCTGAACAATTGCCTGCCTTTGG	PRPF4B	ENSG00000112739	-0.37677960352580764	[1004]	[964,661,995,928]	-5	hSpCas9	negative selection	6841605
4021443	4021466	6	-	27260156	G402	viability	CTGGCTGCTCCCGTAGCGACTGG	PRPF4B	ENSG00000112739	-0.32080697395703994	[627]	[1117,623,336,453]	-4	hSpCas9	negative selection	6898595
4043872	4043895	6	-	27260156	G402	viability	ATCGTGTTCTCGTACTGCTCTGG	PRPF4B	ENSG00000112739	-0.202612335261101	[864]	[868,617,1282,872]	-3	hSpCas9	negative selection	6898596
4021416	4021439	6	+	27260156	G402	viability	GAAGTTCAAGATGGCCGCCGCGG	PRPF4B	ENSG00000112739	0.47631205732324144	[261]	[639,438,553,184]	6	hSpCas9	negative selection	6898597
4043824	4043847	6	-	27260156	G402	viability	ACATGTTGCTATCTTCAGCAAGG	PRPF4B	ENSG00000112739	-0.6418771945725225	[533]	[504,376,209,578]	-7	hSpCas9	negative selection	6962854
4042487	4042510	6	-	27260156	G402	viability	CCTCTACATCAAAGTCTTCAAGG	PRPF4B	ENSG00000112739	-0.34500549342011266	[422]	[511,395,312,416]	-4	hSpCas9	negative selection	6962855
4042547	4042570	6	-	27260156	G402	viability	CCTGAACAATTGCCTGCCTTTGG	PRPF4B	ENSG00000112739	-0.47124102802914236	[1004]	[956,959,795,838]	-5	hSpCas9	negative selection	6962856
4021443	4021466	6	-	27260156	L33	viability	CTGGCTGCTCCCGTAGCGACTGG	PRPF4B	ENSG00000112739	-0.24152871539819176	[627]	[463,206,470,409]	-5	hSpCas9	negative selection	7019846
4043872	4043895	6	-	27260156	L33	viability	ATCGTGTTCTCGTACTGCTCTGG	PRPF4B	ENSG00000112739	-0.0646982491507212	[864]	[776,369,509,817]	-1	hSpCas9	negative selection	7019847
4021416	4021439	6	+	27260156	L33	viability	GAAGTTCAAGATGGCCGCCGCGG	PRPF4B	ENSG00000112739	0.43934655369122416	[261]	[343,151,216,360]	8	hSpCas9	negative selection	7019848
4043824	4043847	6	-	27260156	L33	viability	ACATGTTGCTATCTTCAGCAAGG	PRPF4B	ENSG00000112739	-0.49240266932021526	[533]	[392,157,228,374]	-8	hSpCas9	negative selection	7084105
4042487	4042510	6	-	27260156	L33	viability	CCTCTACATCAAAGTCTTCAAGG	PRPF4B	ENSG00000112739	0.4388168734067134	[422]	[468,258,369,605]	8	hSpCas9	negative selection	7084106
4042547	4042570	6	-	27260156	L33	viability	CCTGAACAATTGCCTGCCTTTGG	PRPF4B	ENSG00000112739	-0.3265178370828492	[1004]	[781,327,439,921]	-6	hSpCas9	negative selection	7084107
4021443	4021466	6	-	27260156	K562	viability	CTGGCTGCTCCCGTAGCGACTGG	PRPF4B	ENSG00000112739	-0.0810087819595367	[627]	[655,227,640,569]	-1	hSpCas9	negative selection	7141097
4043872	4043895	6	-	27260156	K562	viability	ATCGTGTTCTCGTACTGCTCTGG	PRPF4B	ENSG00000112739	0.18155528143361488	[864]	[864,1372,730,570]	2	hSpCas9	negative selection	7141098
4021416	4021439	6	+	27260156	K562	viability	GAAGTTCAAGATGGCCGCCGCGG	PRPF4B	ENSG00000112739	0.8586892224411363	[261]	[329,129,422,740]	9	hSpCas9	negative selection	7141099
4043824	4043847	6	-	27260156	K562	viability	ACATGTTGCTATCTTCAGCAAGG	PRPF4B	ENSG00000112739	-1.0576885982568522	[533]	[406,218,127,175]	-8	hSpCas9	negative selection	7205356
4042487	4042510	6	-	27260156	K562	viability	CCTCTACATCAAAGTCTTCAAGG	PRPF4B	ENSG00000112739	0.38766770609388984	[422]	[535,508,572,363]	5	hSpCas9	negative selection	7205357
4042547	4042570	6	-	27260156	K562	viability	CCTGAACAATTGCCTGCCTTTGG	PRPF4B	ENSG00000112739	0.054736202278977686	[1004]	[699,1224,718,1040]	0	hSpCas9	negative selection	7205358
4021443	4021466	6	-	27260156	HT29	viability	CTGGCTGCTCCCGTAGCGACTGG	PRPF4B	ENSG00000112739	-0.3182115504809575	[627]	[728,709,472,556]	-6	hSpCas9	negative selection	7262348
4043872	4043895	6	-	27260156	HT29	viability	ATCGTGTTCTCGTACTGCTCTGG	PRPF4B	ENSG00000112739	-0.22409740377105358	[864]	[945,1070,959,664]	-4	hSpCas9	negative selection	7262349
4021416	4021439	6	+	27260156	HT29	viability	GAAGTTCAAGATGGCCGCCGCGG	PRPF4B	ENSG00000112739	0.18373485248124377	[261]	[386,272,374,398]	3	hSpCas9	negative selection	7262350
4043824	4043847	6	-	27260156	HT29	viability	ACATGTTGCTATCTTCAGCAAGG	PRPF4B	ENSG00000112739	-1.274252937683353	[533]	[346,308,164,260]	-9	hSpCas9	negative selection	7326607
4042487	4042510	6	-	27260156	HT29	viability	CCTCTACATCAAAGTCTTCAAGG	PRPF4B	ENSG00000112739	0.045811093169904546	[422]	[476,742,468,453]	0	hSpCas9	negative selection	7326608
4042547	4042570	6	-	27260156	HT29	viability	CCTGAACAATTGCCTGCCTTTGG	PRPF4B	ENSG00000112739	-0.4098086454784303	[1004]	[1273,825,851,758]	-6	hSpCas9	negative selection	7326609
4021443	4021466	6	-	27260156	MHHES1	viability	CTGGCTGCTCCCGTAGCGACTGG	PRPF4B	ENSG00000112739	-0.5066967061326575	[627]	[328,636,456,539]	-7	hSpCas9	negative selection	7383599
4043872	4043895	6	-	27260156	MHHES1	viability	ATCGTGTTCTCGTACTGCTCTGG	PRPF4B	ENSG00000112739	0.03688736767945433	[864]	[1389,1121,858,726]	0	hSpCas9	negative selection	7383600
4021416	4021439	6	+	27260156	MHHES1	viability	GAAGTTCAAGATGGCCGCCGCGG	PRPF4B	ENSG00000112739	0.3769956996401323	[261]	[597,408,246,313]	6	hSpCas9	negative selection	7383601
4043824	4043847	6	-	27260156	MHHES1	viability	ACATGTTGCTATCTTCAGCAAGG	PRPF4B	ENSG00000112739	-1.133373297188512	[533]	[259,381,314,167]	-9	hSpCas9	negative selection	7447858
4042487	4042510	6	-	27260156	MHHES1	viability	CCTCTACATCAAAGTCTTCAAGG	PRPF4B	ENSG00000112739	0.278177805611133	[422]	[436,661,813,415]	5	hSpCas9	negative selection	7447859
4042547	4042570	6	-	27260156	MHHES1	viability	CCTGAACAATTGCCTGCCTTTGG	PRPF4B	ENSG00000112739	-0.3800785723110869	[1004]	[1095,812,972,650]	-6	hSpCas9	negative selection	7447860
4021443	4021466	6	-	27260156	MEWO	viability	CTGGCTGCTCCCGTAGCGACTGG	PRPF4B	ENSG00000112739	-0.6052747471403667	[627]	[409,418,333]	-8	hSpCas9	negative selection	7504850
4043872	4043895	6	-	27260156	MEWO	viability	ATCGTGTTCTCGTACTGCTCTGG	PRPF4B	ENSG00000112739	-0.20042356151704743	[864]	[979,733,451]	-4	hSpCas9	negative selection	7504851
4021416	4021439	6	+	27260156	MEWO	viability	GAAGTTCAAGATGGCCGCCGCGG	PRPF4B	ENSG00000112739	0.8659286656325139	[261]	[691,365,329]	9	hSpCas9	negative selection	7504852
4043824	4043847	6	-	27260156	MEWO	viability	ACATGTTGCTATCTTCAGCAAGG	PRPF4B	ENSG00000112739	-0.8001600864069014	[533]	[411,264,207]	-9	hSpCas9	negative selection	7569109
4042487	4042510	6	-	27260156	MEWO	viability	CCTCTACATCAAAGTCTTCAAGG	PRPF4B	ENSG00000112739	0.3728819785974065	[422]	[637,428,494]	7	hSpCas9	negative selection	7569110
4042547	4042570	6	-	27260156	MEWO	viability	CCTGAACAATTGCCTGCCTTTGG	PRPF4B	ENSG00000112739	-0.28658865472876505	[1004]	[887,782,663]	-6	hSpCas9	negative selection	7569111
4021443	4021466	6	-	27260156	LNCAPCLONEFGC	viability	CTGGCTGCTCCCGTAGCGACTGG	PRPF4B	ENSG00000112739	-0.2704607648755607	[627]	[400,429,583,491]	-4	hSpCas9	negative selection	7626101
4043872	4043895	6	-	27260156	LNCAPCLONEFGC	viability	ATCGTGTTCTCGTACTGCTCTGG	PRPF4B	ENSG00000112739	0.04635379025409325	[864]	[730,834,890,790]	0	hSpCas9	negative selection	7626102
4021416	4021439	6	+	27260156	LNCAPCLONEFGC	viability	GAAGTTCAAGATGGCCGCCGCGG	PRPF4B	ENSG00000112739	0.2593980415561118	[261]	[234,318,298,283]	4	hSpCas9	negative selection	7626103
4043824	4043847	6	-	27260156	LNCAPCLONEFGC	viability	ACATGTTGCTATCTTCAGCAAGG	PRPF4B	ENSG00000112739	-1.0173575757465494	[533]	[266,156,362,191]	-8	hSpCas9	negative selection	7690360
4042487	4042510	6	-	27260156	LNCAPCLONEFGC	viability	CCTCTACATCAAAGTCTTCAAGG	PRPF4B	ENSG00000112739	0.35175801829476816	[422]	[455,566,555,381]	5	hSpCas9	negative selection	7690361
4042547	4042570	6	-	27260156	LNCAPCLONEFGC	viability	CCTGAACAATTGCCTGCCTTTGG	PRPF4B	ENSG00000112739	-0.3573030768189679	[1004]	[850,665,835,507]	-5	hSpCas9	negative selection	7690362
4021443	4021466	6	-	27260156	PANC0327	viability	CTGGCTGCTCCCGTAGCGACTGG	PRPF4B	ENSG00000112739	-0.8277024631162855	[627]	[285,257,297,419]	-8	hSpCas9	negative selection	7747352
4043872	4043895	6	-	27260156	PANC0327	viability	ATCGTGTTCTCGTACTGCTCTGG	PRPF4B	ENSG00000112739	-0.1181320849763069	[864]	[1153,589,421,716]	-2	hSpCas9	negative selection	7747353
4021416	4021439	6	+	27260156	PANC0327	viability	GAAGTTCAAGATGGCCGCCGCGG	PRPF4B	ENSG00000112739	0.1092121546013961	[261]	[264,235,181,323]	1	hSpCas9	negative selection	7747354
4043824	4043847	6	-	27260156	PANC0327	viability	ACATGTTGCTATCTTCAGCAAGG	PRPF4B	ENSG00000112739	-1.9447853212020356	[533]	[160,53,194,94]	-9	hSpCas9	negative selection	7811611
4042487	4042510	6	-	27260156	PANC0327	viability	CCTCTACATCAAAGTCTTCAAGG	PRPF4B	ENSG00000112739	0.07499312552602534	[422]	[581,281,361,386]	1	hSpCas9	negative selection	7811612
4042547	4042570	6	-	27260156	PANC0327	viability	CCTGAACAATTGCCTGCCTTTGG	PRPF4B	ENSG00000112739	0.16573561371349577	[1004]	[1073,1288,785,824]	2	hSpCas9	negative selection	7811613
4021443	4021466	6	-	27260156	NCIH2009	viability	CTGGCTGCTCCCGTAGCGACTGG	PRPF4B	ENSG00000112739	-0.0587118638668816	[627]	[827,896,796]	-1	hSpCas9	negative selection	7868603
4043872	4043895	6	-	27260156	NCIH2009	viability	ATCGTGTTCTCGTACTGCTCTGG	PRPF4B	ENSG00000112739	0.09349455516706695	[864]	[1075,1012,1739]	1	hSpCas9	negative selection	7868604
4021416	4021439	6	+	27260156	NCIH2009	viability	GAAGTTCAAGATGGCCGCCGCGG	PRPF4B	ENSG00000112739	0.42314244352671226	[261]	[566,528,389]	6	hSpCas9	negative selection	7868605
4043824	4043847	6	-	27260156	NCIH2009	viability	ACATGTTGCTATCTTCAGCAAGG	PRPF4B	ENSG00000112739	-2.462582647107154	[533]	[207,90,121]	-9	hSpCas9	negative selection	7932862
4042487	4042510	6	-	27260156	NCIH2009	viability	CCTCTACATCAAAGTCTTCAAGG	PRPF4B	ENSG00000112739	-0.07684932327696417	[422]	[570,569,540]	-1	hSpCas9	negative selection	7932863
4042547	4042570	6	-	27260156	NCIH2009	viability	CCTGAACAATTGCCTGCCTTTGG	PRPF4B	ENSG00000112739	-0.3407645242999491	[1004]	[1331,1189,844]	-4	hSpCas9	negative selection	7932864
4021443	4021466	6	-	27260156	NCIH1373	viability	CTGGCTGCTCCCGTAGCGACTGG	PRPF4B	ENSG00000112739	-0.030306925489737346	[627]	[941,752,414,178]	0	hSpCas9	negative selection	7989854
4043872	4043895	6	-	27260156	NCIH1373	viability	ATCGTGTTCTCGTACTGCTCTGG	PRPF4B	ENSG00000112739	-0.15053599104032223	[864]	[1313,695,765,209]	-1	hSpCas9	negative selection	7989855
4021416	4021439	6	+	27260156	NCIH1373	viability	GAAGTTCAAGATGGCCGCCGCGG	PRPF4B	ENSG00000112739	0.4221758598138808	[261]	[326,523,508,44]	4	hSpCas9	negative selection	7989856
4043824	4043847	6	-	27260156	NCIH1373	viability	ACATGTTGCTATCTTCAGCAAGG	PRPF4B	ENSG00000112739	-1.885486175955587	[533]	[136,286,75,33]	-9	hSpCas9	negative selection	8054113
4042487	4042510	6	-	27260156	NCIH1373	viability	CCTCTACATCAAAGTCTTCAAGG	PRPF4B	ENSG00000112739	0.012130533205115535	[422]	[345,467,233,228]	0	hSpCas9	negative selection	8054114
4042547	4042570	6	-	27260156	NCIH1373	viability	CCTGAACAATTGCCTGCCTTTGG	PRPF4B	ENSG00000112739	-0.12657747163840516	[1004]	[849,897,1458,231]	-1	hSpCas9	negative selection	8054115
4021443	4021466	6	-	27260156	PATU8902	viability	CTGGCTGCTCCCGTAGCGACTGG	PRPF4B	ENSG00000112739	-0.7558574186313098	[627]	[453,431,473,746]	-6	hSpCas9	negative selection	8111105
4043872	4043895	6	-	27260156	PATU8902	viability	ATCGTGTTCTCGTACTGCTCTGG	PRPF4B	ENSG00000112739	0.06657243143360714	[864]	[1640,1250,1142,994]	0	hSpCas9	negative selection	8111106
4021416	4021439	6	+	27260156	PATU8902	viability	GAAGTTCAAGATGGCCGCCGCGG	PRPF4B	ENSG00000112739	-0.39011063904507837	[261]	[431,176,79,497]	-4	hSpCas9	negative selection	8111107
4043824	4043847	6	-	27260156	PATU8902	viability	ACATGTTGCTATCTTCAGCAAGG	PRPF4B	ENSG00000112739	-3.2654987364752968	[533]	[24,63,84,140]	-9	hSpCas9	negative selection	8175364
4042487	4042510	6	-	27260156	PATU8902	viability	CCTCTACATCAAAGTCTTCAAGG	PRPF4B	ENSG00000112739	-0.00843571854004288	[422]	[863,353,151,1142]	0	hSpCas9	negative selection	8175365
4042547	4042570	6	-	27260156	PATU8902	viability	CCTGAACAATTGCCTGCCTTTGG	PRPF4B	ENSG00000112739	-0.6717519870996154	[1004]	[1023,1230,613,682]	-6	hSpCas9	negative selection	8175366
4021443	4021466	6	-	27260156	PANC1	viability	CTGGCTGCTCCCGTAGCGACTGG	PRPF4B	ENSG00000112739	-0.4693826624588299	[627]	[363,391,499,310]	-6	hSpCas9	negative selection	8232356
4043872	4043895	6	-	27260156	PANC1	viability	ATCGTGTTCTCGTACTGCTCTGG	PRPF4B	ENSG00000112739	-0.1108948960517272	[864]	[715,687,644,689]	-2	hSpCas9	negative selection	8232357
4021416	4021439	6	+	27260156	PANC1	viability	GAAGTTCAAGATGGCCGCCGCGG	PRPF4B	ENSG00000112739	-0.2328552828404471	[261]	[274,186,189,119]	-4	hSpCas9	negative selection	8232358
4043824	4043847	6	-	27260156	PANC1	viability	ACATGTTGCTATCTTCAGCAAGG	PRPF4B	ENSG00000112739	-1.7628098738698603	[533]	[197,130,146,70]	-9	hSpCas9	negative selection	8296615
4042487	4042510	6	-	27260156	PANC1	viability	CCTCTACATCAAAGTCTTCAAGG	PRPF4B	ENSG00000112739	-0.02100818422241449	[422]	[377,532,274,286]	0	hSpCas9	negative selection	8296616
4042547	4042570	6	-	27260156	PANC1	viability	CCTGAACAATTGCCTGCCTTTGG	PRPF4B	ENSG00000112739	-0.5076142341816687	[1004]	[651,757,502,544]	-6	hSpCas9	negative selection	8296617
4021443	4021466	6	-	27260156	PANC0813	viability	CTGGCTGCTCCCGTAGCGACTGG	PRPF4B	ENSG00000112739	-0.8681479066012552	[627]	[518,279,274,543]	-8	hSpCas9	negative selection	8353607
4043872	4043895	6	-	27260156	PANC0813	viability	ATCGTGTTCTCGTACTGCTCTGG	PRPF4B	ENSG00000112739	-0.264274692423761	[864]	[811,820,699,1034]	-4	hSpCas9	negative selection	8353608
4021416	4021439	6	+	27260156	PANC0813	viability	GAAGTTCAAGATGGCCGCCGCGG	PRPF4B	ENSG00000112739	0.23967464404669647	[261]	[362,312,256,510]	4	hSpCas9	negative selection	8353609
4043824	4043847	6	-	27260156	PANC0813	viability	ACATGTTGCTATCTTCAGCAAGG	PRPF4B	ENSG00000112739	-1.1712023818739883	[533]	[394,237,312,183]	-9	hSpCas9	negative selection	8417866
4042487	4042510	6	-	27260156	PANC0813	viability	CCTCTACATCAAAGTCTTCAAGG	PRPF4B	ENSG00000112739	-0.10636953537829083	[422]	[533,451,371,491]	-2	hSpCas9	negative selection	8417867
4042547	4042570	6	-	27260156	PANC0813	viability	CCTGAACAATTGCCTGCCTTTGG	PRPF4B	ENSG00000112739	-0.2901016604812543	[1004]	[1084,1038,893,858]	-4	hSpCas9	negative selection	8417868
4021443	4021466	6	-	27260156	RDES	viability	CTGGCTGCTCCCGTAGCGACTGG	PRPF4B	ENSG00000112739	-0.2658166373117814	[627]	[467,617,527,829]	-4	hSpCas9	negative selection	8474858
4043872	4043895	6	-	27260156	RDES	viability	ATCGTGTTCTCGTACTGCTCTGG	PRPF4B	ENSG00000112739	-0.2238102742464413	[864]	[702,934,790,994]	-4	hSpCas9	negative selection	8474859
4021416	4021439	6	+	27260156	RDES	viability	GAAGTTCAAGATGGCCGCCGCGG	PRPF4B	ENSG00000112739	0.36428068073430975	[261]	[291,447,427,387]	6	hSpCas9	negative selection	8474860
4043824	4043847	6	-	27260156	RDES	viability	ACATGTTGCTATCTTCAGCAAGG	PRPF4B	ENSG00000112739	-1.3330890554751351	[533]	[204,275,214,280]	-9	hSpCas9	negative selection	8539117
4042487	4042510	6	-	27260156	RDES	viability	CCTCTACATCAAAGTCTTCAAGG	PRPF4B	ENSG00000112739	0.06569790435092877	[422]	[375,473,733,472]	1	hSpCas9	negative selection	8539118
4042547	4042570	6	-	27260156	RDES	viability	CCTGAACAATTGCCTGCCTTTGG	PRPF4B	ENSG00000112739	-0.18074597102280998	[1004]	[750,1023,1089,1284]	-3	hSpCas9	negative selection	8539119
4021443	4021466	6	-	27260156	PC3	viability	CTGGCTGCTCCCGTAGCGACTGG	PRPF4B	ENSG00000112739	-0.37442515547073696	[627]	[233,426,926,596]	-7	hSpCas9	negative selection	8596109
4043872	4043895	6	-	27260156	PC3	viability	ATCGTGTTCTCGTACTGCTCTGG	PRPF4B	ENSG00000112739	-0.20391851090062996	[864]	[410,618,1646,759]	-4	hSpCas9	negative selection	8596110
4021416	4021439	6	+	27260156	PC3	viability	GAAGTTCAAGATGGCCGCCGCGG	PRPF4B	ENSG00000112739	0.04265511038097192	[261]	[170,217,411,353]	1	hSpCas9	negative selection	8596111
4043824	4043847	6	-	27260156	PC3	viability	ACATGTTGCTATCTTCAGCAAGG	PRPF4B	ENSG00000112739	-0.6177547144844945	[533]	[210,477,508,266]	-8	hSpCas9	negative selection	8660368
4042487	4042510	6	-	27260156	PC3	viability	CCTCTACATCAAAGTCTTCAAGG	PRPF4B	ENSG00000112739	0.5916696221517813	[422]	[493,534,1073,600]	9	hSpCas9	negative selection	8660369
4042547	4042570	6	-	27260156	PC3	viability	CCTGAACAATTGCCTGCCTTTGG	PRPF4B	ENSG00000112739	-0.5090015452872889	[1004]	[482,698,943,809]	-8	hSpCas9	negative selection	8660370
4021443	4021466	6	-	27260156	PATU8988T	viability	CTGGCTGCTCCCGTAGCGACTGG	PRPF4B	ENSG00000112739	-0.46657205806205565	[627]	[354,477,462,465]	-6	hSpCas9	negative selection	8717360
4043872	4043895	6	-	27260156	PATU8988T	viability	ATCGTGTTCTCGTACTGCTCTGG	PRPF4B	ENSG00000112739	-0.19096612613218555	[864]	[830,869,625,605]	-3	hSpCas9	negative selection	8717361
4021416	4021439	6	+	27260156	PATU8988T	viability	GAAGTTCAAGATGGCCGCCGCGG	PRPF4B	ENSG00000112739	0.49480854452464906	[261]	[247,278,466,429]	8	hSpCas9	negative selection	8717362
4043824	4043847	6	-	27260156	PATU8988T	viability	ACATGTTGCTATCTTCAGCAAGG	PRPF4B	ENSG00000112739	-0.30184280417428955	[533]	[612,453,250,356]	-5	hSpCas9	negative selection	8781619
4042487	4042510	6	-	27260156	PATU8988T	viability	CCTCTACATCAAAGTCTTCAAGG	PRPF4B	ENSG00000112739	0.11321256936160518	[422]	[194,522,608,446]	2	hSpCas9	negative selection	8781620
4042547	4042570	6	-	27260156	PATU8988T	viability	CCTGAACAATTGCCTGCCTTTGG	PRPF4B	ENSG00000112739	-0.5853677418364457	[1004]	[554,707,722,603]	-7	hSpCas9	negative selection	8781621
4021443	4021466	6	-	27260156	T47D	viability	CTGGCTGCTCCCGTAGCGACTGG	PRPF4B	ENSG00000112739	-0.5994190108186928	[627]	[600,393,500,441]	-8	hSpCas9	negative selection	8838611
4043872	4043895	6	-	27260156	T47D	viability	ATCGTGTTCTCGTACTGCTCTGG	PRPF4B	ENSG00000112739	-0.09412666401261105	[864]	[1014,859,1029,874]	-2	hSpCas9	negative selection	8838612
4021416	4021439	6	+	27260156	T47D	viability	GAAGTTCAAGATGGCCGCCGCGG	PRPF4B	ENSG00000112739	0.37626961007329573	[261]	[437,400,411,330]	7	hSpCas9	negative selection	8838613
4043824	4043847	6	-	27260156	T47D	viability	ACATGTTGCTATCTTCAGCAAGG	PRPF4B	ENSG00000112739	-0.8073361731989639	[533]	[338,296,446,341]	-9	hSpCas9	negative selection	8902870
4042487	4042510	6	-	27260156	T47D	viability	CCTCTACATCAAAGTCTTCAAGG	PRPF4B	ENSG00000112739	0.2667482682981112	[422]	[602,596,500,673]	5	hSpCas9	negative selection	8902871
4042547	4042570	6	-	27260156	T47D	viability	CCTGAACAATTGCCTGCCTTTGG	PRPF4B	ENSG00000112739	-0.45475542737901953	[1004]	[782,817,838,983]	-7	hSpCas9	negative selection	8902872
4021443	4021466	6	-	27260156	SU8686	viability	CTGGCTGCTCCCGTAGCGACTGG	PRPF4B	ENSG00000112739	-0.42258485648553135	[627]	[393,401,564,521]	-6	hSpCas9	negative selection	8959862
4043872	4043895	6	-	27260156	SU8686	viability	ATCGTGTTCTCGTACTGCTCTGG	PRPF4B	ENSG00000112739	-0.3765868869822563	[864]	[620,639,570,838]	-6	hSpCas9	negative selection	8959863
4021416	4021439	6	+	27260156	SU8686	viability	GAAGTTCAAGATGGCCGCCGCGG	PRPF4B	ENSG00000112739	0.3819274554946905	[261]	[348,277,397,333]	6	hSpCas9	negative selection	8959864
4043824	4043847	6	-	27260156	SU8686	viability	ACATGTTGCTATCTTCAGCAAGG	PRPF4B	ENSG00000112739	-2.024638088594446	[533]	[122,146,115,131]	-9	hSpCas9	negative selection	9024121
4042487	4042510	6	-	27260156	SU8686	viability	CCTCTACATCAAAGTCTTCAAGG	PRPF4B	ENSG00000112739	0.10005531440455179	[422]	[458,323,484,560]	1	hSpCas9	negative selection	9024122
4042547	4042570	6	-	27260156	SU8686	viability	CCTGAACAATTGCCTGCCTTTGG	PRPF4B	ENSG00000112739	-0.4660501686153199	[1004]	[705,589,676,963]	-6	hSpCas9	negative selection	9024123
4021443	4021466	6	-	27260156	SKES1	viability	CTGGCTGCTCCCGTAGCGACTGG	PRPF4B	ENSG00000112739	-0.1750762589880222	[627]	[621,626,551,443]	-4	hSpCas9	negative selection	9081113
4043872	4043895	6	-	27260156	SKES1	viability	ATCGTGTTCTCGTACTGCTCTGG	PRPF4B	ENSG00000112739	-0.18138001388849267	[864]	[788,964,854,486]	-4	hSpCas9	negative selection	9081114
4021416	4021439	6	+	27260156	SKES1	viability	GAAGTTCAAGATGGCCGCCGCGG	PRPF4B	ENSG00000112739	0.4186899719844962	[261]	[510,264,313,319]	8	hSpCas9	negative selection	9081115
4043824	4043847	6	-	27260156	SKES1	viability	ACATGTTGCTATCTTCAGCAAGG	PRPF4B	ENSG00000112739	-0.9002030063891898	[533]	[385,300,257,217]	-9	hSpCas9	negative selection	9145372
4042487	4042510	6	-	27260156	SKES1	viability	CCTCTACATCAAAGTCTTCAAGG	PRPF4B	ENSG00000112739	0.29710008385620834	[422]	[385,640,595,448]	6	hSpCas9	negative selection	9145373
4042547	4042570	6	-	27260156	SKES1	viability	CCTGAACAATTGCCTGCCTTTGG	PRPF4B	ENSG00000112739	-0.629268560600287	[1004]	[615,748,682,555]	-8	hSpCas9	negative selection	9145374
4021443	4021466	6	-	27260156	TOV112D	viability	CTGGCTGCTCCCGTAGCGACTGG	PRPF4B	ENSG00000112739	-0.3092864171494284	[627]	[562,672,332,505]	-6	hSpCas9	negative selection	9202364
4043872	4043895	6	-	27260156	TOV112D	viability	ATCGTGTTCTCGTACTGCTCTGG	PRPF4B	ENSG00000112739	-0.2124329089735717	[864]	[654,1053,773,578]	-4	hSpCas9	negative selection	9202365
4021416	4021439	6	+	27260156	TOV112D	viability	GAAGTTCAAGATGGCCGCCGCGG	PRPF4B	ENSG00000112739	0.2843738619670507	[261]	[338,371,249,330]	5	hSpCas9	negative selection	9202366
4043824	4043847	6	-	27260156	TOV112D	viability	ACATGTTGCTATCTTCAGCAAGG	PRPF4B	ENSG00000112739	-0.5573212726692846	[533]	[347,542,274,330]	-8	hSpCas9	negative selection	9266623
4042487	4042510	6	-	27260156	TOV112D	viability	CCTCTACATCAAAGTCTTCAAGG	PRPF4B	ENSG00000112739	0.3247229235880005	[422]	[627,684,515,343]	6	hSpCas9	negative selection	9266624
4042547	4042570	6	-	27260156	TOV112D	viability	CCTGAACAATTGCCTGCCTTTGG	PRPF4B	ENSG00000112739	-0.4971598573678728	[1004]	[760,820,768,535]	-7	hSpCas9	negative selection	9266625
4021443	4021466	6	-	27260156	TC71	viability	CTGGCTGCTCCCGTAGCGACTGG	PRPF4B	ENSG00000112739	-0.2546774619493023	[627]	[380,662,631,583]	-6	hSpCas9	negative selection	9323615
4043872	4043895	6	-	27260156	TC71	viability	ATCGTGTTCTCGTACTGCTCTGG	PRPF4B	ENSG00000112739	-0.05515862387376835	[864]	[818,911,941,896]	-1	hSpCas9	negative selection	9323616
4021416	4021439	6	+	27260156	TC71	viability	GAAGTTCAAGATGGCCGCCGCGG	PRPF4B	ENSG00000112739	0.1813035168043169	[261]	[314,276,266,422]	4	hSpCas9	negative selection	9323617
4043824	4043847	6	-	27260156	TC71	viability	ACATGTTGCTATCTTCAGCAAGG	PRPF4B	ENSG00000112739	-0.2587740689131324	[533]	[461,572,407,472]	-6	hSpCas9	negative selection	9387874
4042487	4042510	6	-	27260156	TC71	viability	CCTCTACATCAAAGTCTTCAAGG	PRPF4B	ENSG00000112739	0.3138842988027445	[422]	[586,453,499,724]	7	hSpCas9	negative selection	9387875
4042547	4042570	6	-	27260156	TC71	viability	CCTGAACAATTGCCTGCCTTTGG	PRPF4B	ENSG00000112739	-0.40112546501373647	[1004]	[818,882,690,877]	-8	hSpCas9	negative selection	9387876
4021443	4021466	6	-	27260156	TC32	viability	CTGGCTGCTCCCGTAGCGACTGG	PRPF4B	ENSG00000112739	-0.6721643089604167	[627]	[283,243,611,424]	-8	hSpCas9	negative selection	9444866
4043872	4043895	6	-	27260156	TC32	viability	ATCGTGTTCTCGTACTGCTCTGG	PRPF4B	ENSG00000112739	-0.3499341267102982	[864]	[659,478,752,700]	-6	hSpCas9	negative selection	9444867
4021416	4021439	6	+	27260156	TC32	viability	GAAGTTCAAGATGGCCGCCGCGG	PRPF4B	ENSG00000112739	0.2532465056707871	[261]	[345,222,322,287]	4	hSpCas9	negative selection	9444868
4043824	4043847	6	-	27260156	TC32	viability	ACATGTTGCTATCTTCAGCAAGG	PRPF4B	ENSG00000112739	-0.735028922446202	[533]	[318,204,381,331]	-9	hSpCas9	negative selection	9509125
4042487	4042510	6	-	27260156	TC32	viability	CCTCTACATCAAAGTCTTCAAGG	PRPF4B	ENSG00000112739	0.16516176482244668	[422]	[527,397,451,379]	3	hSpCas9	negative selection	9509126
4042547	4042570	6	-	27260156	TC32	viability	CCTGAACAATTGCCTGCCTTTGG	PRPF4B	ENSG00000112739	-0.7101347066213721	[1004]	[490,358,979,612]	-8	hSpCas9	negative selection	9509127
4021430	4021453	6	-	27869803	HPAFII	viability after 27 days	TAGCGACTGGGTCTCCGCGGCGG	PRPF4B	ENSG00000112739	-0.49916254555541917	[119]	[0,80,NaN]	-4	hSpCas9	negative selection	9595913
4021443	4021466	6	-	27869803	HPAFII	viability after 27 days	CTGGCTGCTCCCGTAGCGACTGG	PRPF4B	ENSG00000112739	-1.0202682635731897	[651]	[168,168,NaN]	-6	hSpCas9	negative selection	9595914
4032661	4032684	6	-	27869803	HPAFII	viability after 27 days	CCAGGAGACAGTGTCCGCGAGGG	PRPF4B	ENSG00000112739	-1.8611587895145538	[685]	[83,111,NaN]	-8	hSpCas9	negative selection	9595915
4032662	4032685	6	-	27869803	HPAFII	viability after 27 days	CCCAGGAGACAGTGTCCGCGAGG	PRPF4B	ENSG00000112739	-0.9339019592768113	[810]	[322,139,NaN]	-6	hSpCas9	negative selection	9595916
4040803	4040826	6	+	27869803	HPAFII	viability after 27 days	CGAAGGCGGTCTCGATCACGCGG	PRPF4B	ENSG00000112739	-2.3969215841754847	[50]	[3,5,NaN]	-8	hSpCas9	negative selection	9595922
4049016	4049039	6	+	27869803	HPAFII	viability after 27 days	AGTGCTCGTCTTCGGGCCGCTGG	PRPF4B	ENSG00000112739	-5.180944002402466	[68]	[0,0,NaN]	-9	hSpCas9	negative selection	9595923
4021430	4021453	6	-	27869803	HPAFII	viability after 15 days	TAGCGACTGGGTCTCCGCGGCGG	PRPF4B	ENSG00000112739	-1.9885754971174143	[119]	[13,43,NaN]	-9	hSpCas9	negative selection	9678362
4021443	4021466	6	-	27869803	HPAFII	viability after 15 days	CTGGCTGCTCCCGTAGCGACTGG	PRPF4B	ENSG00000112739	-0.7503094536611398	[651]	[558,327,NaN]	-7	hSpCas9	negative selection	9678363
4032661	4032684	6	-	27869803	HPAFII	viability after 15 days	CCAGGAGACAGTGTCCGCGAGGG	PRPF4B	ENSG00000112739	-2.4190854418667573	[685]	[135,138,NaN]	-9	hSpCas9	negative selection	9678364
4032662	4032685	6	-	27869803	HPAFII	viability after 15 days	CCCAGGAGACAGTGTCCGCGAGG	PRPF4B	ENSG00000112739	-0.9207518253419761	[810]	[756,275,NaN]	-7	hSpCas9	negative selection	9678365
4040803	4040826	6	+	27869803	HPAFII	viability after 15 days	CGAAGGCGGTCTCGATCACGCGG	PRPF4B	ENSG00000112739	-1.097392088408665	[50]	[24,25,NaN]	-8	hSpCas9	negative selection	9678371
4049016	4049039	6	+	27869803	HPAFII	viability after 15 days	AGTGCTCGTCTTCGGGCCGCTGG	PRPF4B	ENSG00000112739	-6.212498740532338	[68]	[0,0,NaN]	-9	hSpCas9	negative selection	9678372
4021430	4021453	6	-	27869803	ASPC1	viability after 36 days	TAGCGACTGGGTCTCCGCGGCGG	PRPF4B	ENSG00000112739	-0.6057361868539306	[238]	[88,0,72]	-6	hSpCas9	negative selection	9760811
4021443	4021466	6	-	27869803	ASPC1	viability after 36 days	CTGGCTGCTCCCGTAGCGACTGG	PRPF4B	ENSG00000112739	-0.5334366949601455	[1363]	[669,128,244]	-5	hSpCas9	negative selection	9760812
4032661	4032684	6	-	27869803	ASPC1	viability after 36 days	CCAGGAGACAGTGTCCGCGAGGG	PRPF4B	ENSG00000112739	-1.099564954386467	[1292]	[236,110,268]	-8	hSpCas9	negative selection	9760813
4032662	4032685	6	-	27869803	ASPC1	viability after 36 days	CCCAGGAGACAGTGTCCGCGAGG	PRPF4B	ENSG00000112739	0.1325866514239269	[1950]	[707,826,701]	1	hSpCas9	negative selection	9760814
4040803	4040826	6	+	27869803	ASPC1	viability after 36 days	CGAAGGCGGTCTCGATCACGCGG	PRPF4B	ENSG00000112739	-0.2893322550976585	[126]	[51,54,9]	-3	hSpCas9	negative selection	9760820
4049016	4049039	6	+	27869803	ASPC1	viability after 36 days	AGTGCTCGTCTTCGGGCCGCTGG	PRPF4B	ENSG00000112739	0.10072333496716879	[224]	[0,35,179]	1	hSpCas9	negative selection	9760821
4021430	4021453	6	-	27869803	PATU8988S	viability after 35 days	TAGCGACTGGGTCTCCGCGGCGG	PRPF4B	ENSG00000112739	0.5067050770827479	[220]	[109,142,NaN]	5	hSpCas9	negative selection	9843260
4021443	4021466	6	-	27869803	PATU8988S	viability after 35 days	CTGGCTGCTCCCGTAGCGACTGG	PRPF4B	ENSG00000112739	0.813466378000202	[876]	[508,732,NaN]	8	hSpCas9	negative selection	9843261
4032661	4032684	6	-	27869803	PATU8988S	viability after 35 days	CCAGGAGACAGTGTCCGCGAGGG	PRPF4B	ENSG00000112739	-1.606213249849667	[1485]	[230,161,NaN]	-8	hSpCas9	negative selection	9843262
4032662	4032685	6	-	27869803	PATU8988S	viability after 35 days	CCCAGGAGACAGTGTCCGCGAGG	PRPF4B	ENSG00000112739	-0.3218598058777702	[1791]	[537,616,NaN]	-3	hSpCas9	negative selection	9843263
4040803	4040826	6	+	27869803	PATU8988S	viability after 35 days	CGAAGGCGGTCTCGATCACGCGG	PRPF4B	ENSG00000112739	-0.20930452448195913	[128]	[17,71,NaN]	-2	hSpCas9	negative selection	9843269
4049016	4049039	6	+	27869803	PATU8988S	viability after 35 days	AGTGCTCGTCTTCGGGCCGCTGG	PRPF4B	ENSG00000112739	1.3514644337007753	[148]	[208,96,NaN]	9	hSpCas9	negative selection	9843270
4021430	4021453	6	-	27869803	PATU8988S	viability after 31 days	TAGCGACTGGGTCTCCGCGGCGG	PRPF4B	ENSG00000112739	0.6524839397949161	[220]	[123,156,NaN]	7	hSpCas9	negative selection	9925709
4021443	4021466	6	-	27869803	PATU8988S	viability after 31 days	CTGGCTGCTCCCGTAGCGACTGG	PRPF4B	ENSG00000112739	0.8997955504680004	[876]	[395,978,NaN]	8	hSpCas9	negative selection	9925710
4032661	4032684	6	-	27869803	PATU8988S	viability after 31 days	CCAGGAGACAGTGTCCGCGAGGG	PRPF4B	ENSG00000112739	-1.6342647199113234	[1485]	[167,219,NaN]	-8	hSpCas9	negative selection	9925711
4032662	4032685	6	-	27869803	PATU8988S	viability after 31 days	CCCAGGAGACAGTGTCCGCGAGG	PRPF4B	ENSG00000112739	-0.06605630700069343	[1791]	[532,872,NaN]	0	hSpCas9	negative selection	9925712
4040803	4040826	6	+	27869803	PATU8988S	viability after 31 days	CGAAGGCGGTCTCGATCACGCGG	PRPF4B	ENSG00000112739	-0.6634495577278381	[128]	[13,55,NaN]	-6	hSpCas9	negative selection	9925718
4049016	4049039	6	+	27869803	PATU8988S	viability after 31 days	AGTGCTCGTCTTCGGGCCGCTGG	PRPF4B	ENSG00000112739	1.706688666190781	[148]	[240,133,NaN]	9	hSpCas9	negative selection	9925719
4021430	4021453	6	-	27869803	HPAFII	viability after 35 days	TAGCGACTGGGTCTCCGCGGCGG	PRPF4B	ENSG00000112739	0.8395582121719075	[119]	[0,229,NaN]	5	hSpCas9	negative selection	10008158
4021443	4021466	6	-	27869803	HPAFII	viability after 35 days	CTGGCTGCTCCCGTAGCGACTGG	PRPF4B	ENSG00000112739	-2.0729271560362816	[651]	[37,123,NaN]	-8	hSpCas9	negative selection	10008159
4032661	4032684	6	-	27869803	HPAFII	viability after 35 days	CCAGGAGACAGTGTCCGCGAGGG	PRPF4B	ENSG00000112739	-2.610291076504886	[685]	[38,76,NaN]	-8	hSpCas9	negative selection	10008160
4032662	4032685	6	-	27869803	HPAFII	viability after 35 days	CCCAGGAGACAGTGTCCGCGAGG	PRPF4B	ENSG00000112739	-0.4193932804062783	[810]	[417,181,NaN]	-3	hSpCas9	negative selection	10008161
4040803	4040826	6	+	27869803	HPAFII	viability after 35 days	CGAAGGCGGTCTCGATCACGCGG	PRPF4B	ENSG00000112739	-3.420664931218882	[50]	[0,3,NaN]	-8	hSpCas9	negative selection	10008167
4049016	4049039	6	+	27869803	HPAFII	viability after 35 days	AGTGCTCGTCTTCGGGCCGCTGG	PRPF4B	ENSG00000112739	-5.126435903781495	[68]	[0,0,NaN]	-9	hSpCas9	negative selection	10008168
4021430	4021453	6	-	27869803	HPAFII	viability after 31 days	TAGCGACTGGGTCTCCGCGGCGG	PRPF4B	ENSG00000112739	0.4932957580776358	[119]	[0,196,NaN]	3	hSpCas9	negative selection	10090607
4021443	4021466	6	-	27869803	HPAFII	viability after 31 days	CTGGCTGCTCCCGTAGCGACTGG	PRPF4B	ENSG00000112739	-1.0701055722207622	[651]	[79,276,NaN]	-6	hSpCas9	negative selection	10090608
4032661	4032684	6	-	27869803	HPAFII	viability after 31 days	CCAGGAGACAGTGTCCGCGAGGG	PRPF4B	ENSG00000112739	-2.0104017535155476	[685]	[40,154,NaN]	-8	hSpCas9	negative selection	10090609
4032662	4032685	6	-	27869803	HPAFII	viability after 31 days	CCCAGGAGACAGTGTCCGCGAGG	PRPF4B	ENSG00000112739	-0.9468890272511368	[810]	[338,123,NaN]	-5	hSpCas9	negative selection	10090610
4040803	4040826	6	+	27869803	HPAFII	viability after 31 days	CGAAGGCGGTCTCGATCACGCGG	PRPF4B	ENSG00000112739	-1.503791408907265	[50]	[0,19,NaN]	-7	hSpCas9	negative selection	10090616
4049016	4049039	6	+	27869803	HPAFII	viability after 31 days	AGTGCTCGTCTTCGGGCCGCTGG	PRPF4B	ENSG00000112739	-5.275153257102911	[68]	[0,0,NaN]	-9	hSpCas9	negative selection	10090617
4040786	4040809	6	+	28162770	P31FUJ	viability	GGAGCAGATCACGCTTGCGAAGG	PRPF4B	ENSG00000112739	-0.260023673149403	[106]	[104]	-2	hSpCas9	negative selection	10217678
4049032	4049055	6	-	28162770	P31FUJ	viability	GAAATCTTTTCCAATGCCAGCGG	PRPF4B	ENSG00000112739	-0.9142275446368261	[602]	[375]	-6	hSpCas9	negative selection	10217679
4040806	4040829	6	+	28162770	P31FUJ	viability	AGGCGGTCTCGATCACGCGGTGG	PRPF4B	ENSG00000112739	-0.3202650456647178	[33]	[31]	-3	hSpCas9	negative selection	10217680
4021416	4021439	6	+	28162770	P31FUJ	viability	GAAGTTCAAGATGGCCGCCGCGG	PRPF4B	ENSG00000112739	-0.5832994514985117	[152]	[119]	-5	hSpCas9	negative selection	10217681
4021430	4021453	6	-	28162770	P31FUJ	viability	TAGCGACTGGGTCTCCGCGGCGG	PRPF4B	ENSG00000112739	0.9066008522510377	[68]	[151]	9	hSpCas9	negative selection	10217682
4032661	4032684	6	-	28162770	P31FUJ	viability	CCAGGAGACAGTGTCCGCGAGGG	PRPF4B	ENSG00000112739	-1.3912315670188615	[124]	[55]	-7	hSpCas9	negative selection	10217683
4031937	4031960	6	+	28162770	P31FUJ	viability	TGAGTCTGGCTCTGAAGAAGAGG	PRPF4B	ENSG00000112739	-0.5926981495007613	[769]	[599]	-5	hSpCas9	negative selection	10217684
4032241	4032264	6	-	28162770	P31FUJ	viability	TGAGATCGCCTTCTAAGGGTAGG	PRPF4B	ENSG00000112739	-1.1962763283892646	[194]	[99]	-7	hSpCas9	negative selection	10217685
4032713	4032736	6	+	28162770	P31FUJ	viability	GAAAACGACGAGAACCAGAGAGG	PRPF4B	ENSG00000112739	-2.8177647051355343	[59]	[9]	-9	hSpCas9	negative selection	10217686
4040765	4040788	6	+	28162770	P31FUJ	viability	TAAATAGGGACAGAGGTCGGAGG	PRPF4B	ENSG00000112739	-0.20792753577534945	[344]	[350]	-2	hSpCas9	negative selection	10217687
4040786	4040809	6	+	28162770	TF1	viability	GGAGCAGATCACGCTTGCGAAGG	PRPF4B	ENSG00000112739	NaN	[NaN]	[8]	1	hSpCas9	negative selection	10387044
4049032	4049055	6	-	28162770	TF1	viability	GAAATCTTTTCCAATGCCAGCGG	PRPF4B	ENSG00000112739	NaN	[NaN]	[300]	1	hSpCas9	negative selection	10387045
4040806	4040829	6	+	28162770	TF1	viability	AGGCGGTCTCGATCACGCGGTGG	PRPF4B	ENSG00000112739	NaN	[NaN]	[19]	1	hSpCas9	negative selection	10387046
4021416	4021439	6	+	28162770	TF1	viability	GAAGTTCAAGATGGCCGCCGCGG	PRPF4B	ENSG00000112739	NaN	[NaN]	[146]	1	hSpCas9	negative selection	10387047
4021430	4021453	6	-	28162770	TF1	viability	TAGCGACTGGGTCTCCGCGGCGG	PRPF4B	ENSG00000112739	NaN	[NaN]	[22]	1	hSpCas9	negative selection	10387048
4032661	4032684	6	-	28162770	TF1	viability	CCAGGAGACAGTGTCCGCGAGGG	PRPF4B	ENSG00000112739	NaN	[NaN]	[48]	1	hSpCas9	negative selection	10387049
4031937	4031960	6	+	28162770	TF1	viability	TGAGTCTGGCTCTGAAGAAGAGG	PRPF4B	ENSG00000112739	NaN	[NaN]	[398]	1	hSpCas9	negative selection	10387050
4032241	4032264	6	-	28162770	TF1	viability	TGAGATCGCCTTCTAAGGGTAGG	PRPF4B	ENSG00000112739	NaN	[NaN]	[174]	1	hSpCas9	negative selection	10387051
4032713	4032736	6	+	28162770	TF1	viability	GAAAACGACGAGAACCAGAGAGG	PRPF4B	ENSG00000112739	NaN	[NaN]	[8]	1	hSpCas9	negative selection	10387052
4040765	4040788	6	+	28162770	TF1	viability	TAAATAGGGACAGAGGTCGGAGG	PRPF4B	ENSG00000112739	NaN	[NaN]	[189]	1	hSpCas9	negative selection	10387053
4040786	4040809	6	+	28162770	SKM1	viability	GGAGCAGATCACGCTTGCGAAGG	PRPF4B	ENSG00000112739	0.2672656400750819	[46]	[99]	2	hSpCas9	negative selection	10556410
4049032	4049055	6	-	28162770	SKM1	viability	GAAATCTTTTCCAATGCCAGCGG	PRPF4B	ENSG00000112739	-0.47640469724101087	[132]	[168]	-4	hSpCas9	negative selection	10556411
4040806	4040829	6	+	28162770	SKM1	viability	AGGCGGTCTCGATCACGCGGTGG	PRPF4B	ENSG00000112739	-0.20309186537751156	[27]	[42]	-2	hSpCas9	negative selection	10556412
4021416	4021439	6	+	28162770	SKM1	viability	GAAGTTCAAGATGGCCGCCGCGG	PRPF4B	ENSG00000112739	-1.1044014287227304	[44]	[36]	-7	hSpCas9	negative selection	10556413
4021430	4021453	6	-	28162770	SKM1	viability	TAGCGACTGGGTCTCCGCGGCGG	PRPF4B	ENSG00000112739	-1.07725875326408	[36]	[30]	-7	hSpCas9	negative selection	10556414
4032661	4032684	6	-	28162770	SKM1	viability	CCAGGAGACAGTGTCCGCGAGGG	PRPF4B	ENSG00000112739	-0.06300979752580038	[25]	[43]	0	hSpCas9	negative selection	10556415
4031937	4031960	6	+	28162770	SKM1	viability	TGAGTCTGGCTCTGAAGAAGAGG	PRPF4B	ENSG00000112739	-0.5884110700806938	[164]	[193]	-5	hSpCas9	negative selection	10556416
4032241	4032264	6	-	28162770	SKM1	viability	TGAGATCGCCTTCTAAGGGTAGG	PRPF4B	ENSG00000112739	-1.0482775538456814	[61]	[52]	-6	hSpCas9	negative selection	10556417
4032713	4032736	6	+	28162770	SKM1	viability	GAAAACGACGAGAACCAGAGAGG	PRPF4B	ENSG00000112739	-1.143929792909368	[9]	[7]	-7	hSpCas9	negative selection	10556418
4040765	4040788	6	+	28162770	SKM1	viability	TAAATAGGGACAGAGGTCGGAGG	PRPF4B	ENSG00000112739	0.18710050908524678	[78]	[158]	1	hSpCas9	negative selection	10556419
4040786	4040809	6	+	28162770	SKM1	viability	GGAGCAGATCACGCTTGCGAAGG	PRPF4B	ENSG00000112739	0.2672656400750819	[46]	[99]	2	hSpCas9	negative selection	10725776
4049032	4049055	6	-	28162770	SKM1	viability	GAAATCTTTTCCAATGCCAGCGG	PRPF4B	ENSG00000112739	-0.47640469724101087	[132]	[168]	-4	hSpCas9	negative selection	10725777
4040806	4040829	6	+	28162770	SKM1	viability	AGGCGGTCTCGATCACGCGGTGG	PRPF4B	ENSG00000112739	-0.20309186537751156	[27]	[42]	-2	hSpCas9	negative selection	10725778
4021416	4021439	6	+	28162770	SKM1	viability	GAAGTTCAAGATGGCCGCCGCGG	PRPF4B	ENSG00000112739	-1.1044014287227304	[44]	[36]	-7	hSpCas9	negative selection	10725779
4021430	4021453	6	-	28162770	SKM1	viability	TAGCGACTGGGTCTCCGCGGCGG	PRPF4B	ENSG00000112739	-1.07725875326408	[36]	[30]	-7	hSpCas9	negative selection	10725780
4032661	4032684	6	-	28162770	SKM1	viability	CCAGGAGACAGTGTCCGCGAGGG	PRPF4B	ENSG00000112739	-0.06300979752580038	[25]	[43]	0	hSpCas9	negative selection	10725781
4031937	4031960	6	+	28162770	SKM1	viability	TGAGTCTGGCTCTGAAGAAGAGG	PRPF4B	ENSG00000112739	-0.5884110700806938	[164]	[193]	-5	hSpCas9	negative selection	10725782
4032241	4032264	6	-	28162770	SKM1	viability	TGAGATCGCCTTCTAAGGGTAGG	PRPF4B	ENSG00000112739	-1.0482775538456814	[61]	[52]	-6	hSpCas9	negative selection	10725783
4032713	4032736	6	+	28162770	SKM1	viability	GAAAACGACGAGAACCAGAGAGG	PRPF4B	ENSG00000112739	-1.143929792909368	[9]	[7]	-7	hSpCas9	negative selection	10725784
4040765	4040788	6	+	28162770	SKM1	viability	TAAATAGGGACAGAGGTCGGAGG	PRPF4B	ENSG00000112739	0.18710050908524678	[78]	[158]	1	hSpCas9	negative selection	10725785
4040786	4040809	6	+	28162770	PL21	viability	GGAGCAGATCACGCTTGCGAAGG	PRPF4B	ENSG00000112739	0.5919073344453167	[124]	[81]	5	hSpCas9	negative selection	10895142
4049032	4049055	6	-	28162770	PL21	viability	GAAATCTTTTCCAATGCCAGCGG	PRPF4B	ENSG00000112739	0.4363739609793986	[488]	[287]	4	hSpCas9	negative selection	10895143
4040806	4040829	6	+	28162770	PL21	viability	AGGCGGTCTCGATCACGCGGTGG	PRPF4B	ENSG00000112739	-1.164432817806536	[102]	[19]	-7	hSpCas9	negative selection	10895144
4021416	4021439	6	+	28162770	PL21	viability	GAAGTTCAAGATGGCCGCCGCGG	PRPF4B	ENSG00000112739	-0.540101111709747	[146]	[43]	-4	hSpCas9	negative selection	10895145
4021430	4021453	6	-	28162770	PL21	viability	TAGCGACTGGGTCTCCGCGGCGG	PRPF4B	ENSG00000112739	-0.15655389855871904	[104]	[40]	-1	hSpCas9	negative selection	10895146
4032661	4032684	6	-	28162770	PL21	viability	CCAGGAGACAGTGTCCGCGAGGG	PRPF4B	ENSG00000112739	-2.9925054634530754	[127]	[6]	-9	hSpCas9	negative selection	10895147
4031937	4031960	6	+	28162770	PL21	viability	TGAGTCTGGCTCTGAAGAAGAGG	PRPF4B	ENSG00000112739	-1.1342794245812389	[463]	[91]	-6	hSpCas9	negative selection	10895148
4032241	4032264	6	-	28162770	PL21	viability	TGAGATCGCCTTCTAAGGGTAGG	PRPF4B	ENSG00000112739	0.11497223122664288	[156]	[73]	1	hSpCas9	negative selection	10895149
4032713	4032736	6	+	28162770	PL21	viability	GAAAACGACGAGAACCAGAGAGG	PRPF4B	ENSG00000112739	-1.8587540745642488	[24]	[2]	-8	hSpCas9	negative selection	10895150
4040765	4040788	6	+	28162770	PL21	viability	TAAATAGGGACAGAGGTCGGAGG	PRPF4B	ENSG00000112739	-0.3848228862318362	[221]	[73]	-3	hSpCas9	negative selection	10895151
4040786	4040809	6	+	28162770	P31FUJ	viability	GGAGCAGATCACGCTTGCGAAGG	PRPF4B	ENSG00000112739	-0.260023673149403	[106]	[104]	-2	hSpCas9	negative selection	11064508
4049032	4049055	6	-	28162770	P31FUJ	viability	GAAATCTTTTCCAATGCCAGCGG	PRPF4B	ENSG00000112739	-0.9142275446368261	[602]	[375]	-6	hSpCas9	negative selection	11064509
4040806	4040829	6	+	28162770	P31FUJ	viability	AGGCGGTCTCGATCACGCGGTGG	PRPF4B	ENSG00000112739	-0.3202650456647178	[33]	[31]	-3	hSpCas9	negative selection	11064510
4021416	4021439	6	+	28162770	P31FUJ	viability	GAAGTTCAAGATGGCCGCCGCGG	PRPF4B	ENSG00000112739	-0.5832994514985117	[152]	[119]	-5	hSpCas9	negative selection	11064511
4021430	4021453	6	-	28162770	P31FUJ	viability	TAGCGACTGGGTCTCCGCGGCGG	PRPF4B	ENSG00000112739	0.9066008522510377	[68]	[151]	9	hSpCas9	negative selection	11064512
4032661	4032684	6	-	28162770	P31FUJ	viability	CCAGGAGACAGTGTCCGCGAGGG	PRPF4B	ENSG00000112739	-1.3912315670188615	[124]	[55]	-7	hSpCas9	negative selection	11064513
4031937	4031960	6	+	28162770	P31FUJ	viability	TGAGTCTGGCTCTGAAGAAGAGG	PRPF4B	ENSG00000112739	-0.5926981495007613	[769]	[599]	-5	hSpCas9	negative selection	11064514
4032241	4032264	6	-	28162770	P31FUJ	viability	TGAGATCGCCTTCTAAGGGTAGG	PRPF4B	ENSG00000112739	-1.1962763283892646	[194]	[99]	-7	hSpCas9	negative selection	11064515
4032713	4032736	6	+	28162770	P31FUJ	viability	GAAAACGACGAGAACCAGAGAGG	PRPF4B	ENSG00000112739	-2.8177647051355343	[59]	[9]	-9	hSpCas9	negative selection	11064516
4040765	4040788	6	+	28162770	P31FUJ	viability	TAAATAGGGACAGAGGTCGGAGG	PRPF4B	ENSG00000112739	-0.20792753577534945	[344]	[350]	-2	hSpCas9	negative selection	11064517
4040786	4040809	6	+	28162770	OCIAML5	viability	GGAGCAGATCACGCTTGCGAAGG	PRPF4B	ENSG00000112739	-0.7696044106720239	[84]	[89]	-5	hSpCas9	negative selection	11233874
4049032	4049055	6	-	28162770	OCIAML5	viability	GAAATCTTTTCCAATGCCAGCGG	PRPF4B	ENSG00000112739	-1.0553501692527405	[349]	[303]	-6	hSpCas9	negative selection	11233875
4040806	4040829	6	+	28162770	OCIAML5	viability	AGGCGGTCTCGATCACGCGGTGG	PRPF4B	ENSG00000112739	-2.700063477418947	[35]	[9]	-8	hSpCas9	negative selection	11233876
4021416	4021439	6	+	28162770	OCIAML5	viability	GAAGTTCAAGATGGCCGCCGCGG	PRPF4B	ENSG00000112739	1.1664693805734305	[57]	[234]	8	hSpCas9	negative selection	11233877
4021430	4021453	6	-	28162770	OCIAML5	viability	TAGCGACTGGGTCTCCGCGGCGG	PRPF4B	ENSG00000112739	0.5171672388017219	[23]	[61]	4	hSpCas9	negative selection	11233878
4032661	4032684	6	-	28162770	OCIAML5	viability	CCAGGAGACAGTGTCCGCGAGGG	PRPF4B	ENSG00000112739	-1.262854597141483	[112]	[84]	-6	hSpCas9	negative selection	11233879
4031937	4031960	6	+	28162770	OCIAML5	viability	TGAGTCTGGCTCTGAAGAAGAGG	PRPF4B	ENSG00000112739	-0.026658271398741995	[328]	[582]	0	hSpCas9	negative selection	11233880
4032241	4032264	6	-	28162770	OCIAML5	viability	TGAGATCGCCTTCTAAGGGTAGG	PRPF4B	ENSG00000112739	-1.815540694838883	[155]	[79]	-7	hSpCas9	negative selection	11233881
4032713	4032736	6	+	28162770	OCIAML5	viability	GAAAACGACGAGAACCAGAGAGG	PRPF4B	ENSG00000112739	-1.8520665708639967	[37]	[18]	-7	hSpCas9	negative selection	11233882
4040765	4040788	6	+	28162770	OCIAML5	viability	TAAATAGGGACAGAGGTCGGAGG	PRPF4B	ENSG00000112739	-0.5301384759766345	[159]	[199]	-4	hSpCas9	negative selection	11233883
4040786	4040809	6	+	28162770	EOL1	viability	GGAGCAGATCACGCTTGCGAAGG	PRPF4B	ENSG00000112739	-0.025022801586325305	[252]	[130]	0	hSpCas9	negative selection	11403240
4049032	4049055	6	-	28162770	EOL1	viability	GAAATCTTTTCCAATGCCAGCGG	PRPF4B	ENSG00000112739	0.26425618523489414	[628]	[397]	2	hSpCas9	negative selection	11403241
4040806	4040829	6	+	28162770	EOL1	viability	AGGCGGTCTCGATCACGCGGTGG	PRPF4B	ENSG00000112739	-1.1149805926161027	[147]	[35]	-6	hSpCas9	negative selection	11403242
4021416	4021439	6	+	28162770	EOL1	viability	GAAGTTCAAGATGGCCGCCGCGG	PRPF4B	ENSG00000112739	0.39205269074351395	[242]	[167]	3	hSpCas9	negative selection	11403243
4021430	4021453	6	-	28162770	EOL1	viability	TAGCGACTGGGTCTCCGCGGCGG	PRPF4B	ENSG00000112739	-0.23644410510177016	[160]	[71]	-2	hSpCas9	negative selection	11403244
4032661	4032684	6	-	28162770	EOL1	viability	CCAGGAGACAGTGTCCGCGAGGG	PRPF4B	ENSG00000112739	-3.05945174973575	[268]	[16]	-9	hSpCas9	negative selection	11403245
4031937	4031960	6	+	28162770	EOL1	viability	TGAGTCTGGCTCTGAAGAAGAGG	PRPF4B	ENSG00000112739	-1.482627609935339	[609]	[114]	-7	hSpCas9	negative selection	11403246
4032241	4032264	6	-	28162770	EOL1	viability	TGAGATCGCCTTCTAAGGGTAGG	PRPF4B	ENSG00000112739	-1.1214646261863017	[222]	[53]	-6	hSpCas9	negative selection	11403247
4032713	4032736	6	+	28162770	EOL1	viability	GAAAACGACGAGAACCAGAGAGG	PRPF4B	ENSG00000112739	-2.757276268403211	[76]	[5]	-9	hSpCas9	negative selection	11403248
4040765	4040788	6	+	28162770	EOL1	viability	TAAATAGGGACAGAGGTCGGAGG	PRPF4B	ENSG00000112739	-1.0290593229450142	[305]	[78]	-6	hSpCas9	negative selection	11403249
4040786	4040809	6	+	28162770	MOLM13	viability	GGAGCAGATCACGCTTGCGAAGG	PRPF4B	ENSG00000112739	1.1123528940143967	[189]	[296]	8	hSpCas9	negative selection	11572606
4049032	4049055	6	-	28162770	MOLM13	viability	GAAATCTTTTCCAATGCCAGCGG	PRPF4B	ENSG00000112739	-0.45562147598439173	[752]	[396]	-3	hSpCas9	negative selection	11572607
4040806	4040829	6	+	28162770	MOLM13	viability	AGGCGGTCTCGATCACGCGGTGG	PRPF4B	ENSG00000112739	-0.37164594626217506	[135]	[75]	-2	hSpCas9	negative selection	11572608
4021416	4021439	6	+	28162770	MOLM13	viability	GAAGTTCAAGATGGCCGCCGCGG	PRPF4B	ENSG00000112739	0.9413052296175772	[223]	[310]	7	hSpCas9	negative selection	11572609
4021430	4021453	6	-	28162770	MOLM13	viability	TAGCGACTGGGTCTCCGCGGCGG	PRPF4B	ENSG00000112739	0.2070228123934953	[132]	[110]	1	hSpCas9	negative selection	11572610
4032661	4032684	6	-	28162770	MOLM13	viability	CCAGGAGACAGTGTCCGCGAGGG	PRPF4B	ENSG00000112739	-0.9620984592002366	[193]	[71]	-5	hSpCas9	negative selection	11572611
4031937	4031960	6	+	28162770	MOLM13	viability	TGAGTCTGGCTCTGAAGAAGAGG	PRPF4B	ENSG00000112739	-0.48073325908982667	[661]	[342]	-3	hSpCas9	negative selection	11572612
4032241	4032264	6	-	28162770	MOLM13	viability	TGAGATCGCCTTCTAAGGGTAGG	PRPF4B	ENSG00000112739	-0.30704406282064783	[230]	[134]	-2	hSpCas9	negative selection	11572613
4032713	4032736	6	+	28162770	MOLM13	viability	GAAAACGACGAGAACCAGAGAGG	PRPF4B	ENSG00000112739	-4.509390541955338	[62]	[1]	-9	hSpCas9	negative selection	11572614
4040765	4040788	6	+	28162770	MOLM13	viability	TAAATAGGGACAGAGGTCGGAGG	PRPF4B	ENSG00000112739	-1.5759057363351059	[300]	[72]	-7	hSpCas9	negative selection	11572615
4040786	4040809	6	+	28162770	HEL	viability	GGAGCAGATCACGCTTGCGAAGG	PRPF4B	ENSG00000112739	-1.382207525129874	[174]	[42]	-7	hSpCas9	negative selection	11741972
4049032	4049055	6	-	28162770	HEL	viability	GAAATCTTTTCCAATGCCAGCGG	PRPF4B	ENSG00000112739	-0.6858839154610137	[539]	[214]	-4	hSpCas9	negative selection	11741973
4040806	4040829	6	+	28162770	HEL	viability	AGGCGGTCTCGATCACGCGGTGG	PRPF4B	ENSG00000112739	-1.5341389300837227	[103]	[22]	-7	hSpCas9	negative selection	11741974
4021416	4021439	6	+	28162770	HEL	viability	GAAGTTCAAGATGGCCGCCGCGG	PRPF4B	ENSG00000112739	0.027823109177573024	[218]	[142]	0	hSpCas9	negative selection	11741975
4021430	4021453	6	-	28162770	HEL	viability	TAGCGACTGGGTCTCCGCGGCGG	PRPF4B	ENSG00000112739	-0.6373690871923781	[101]	[41]	-4	hSpCas9	negative selection	11741976
4032661	4032684	6	-	28162770	HEL	viability	CCAGGAGACAGTGTCCGCGAGGG	PRPF4B	ENSG00000112739	-3.614649010692295	[152]	[7]	-9	hSpCas9	negative selection	11741977
4031937	4031960	6	+	28162770	HEL	viability	TGAGTCTGGCTCTGAAGAAGAGG	PRPF4B	ENSG00000112739	-0.21206325245970736	[509]	[281]	-1	hSpCas9	negative selection	11741978
4032241	4032264	6	-	28162770	HEL	viability	TGAGATCGCCTTCTAAGGGTAGG	PRPF4B	ENSG00000112739	-1.2066393049529538	[208]	[57]	-6	hSpCas9	negative selection	11741979
4032713	4032736	6	+	28162770	HEL	viability	GAAAACGACGAGAACCAGAGAGG	PRPF4B	ENSG00000112739	-2.5271861694419555	[89]	[9]	-8	hSpCas9	negative selection	11741980
4040765	4040788	6	+	28162770	HEL	viability	TAAATAGGGACAGAGGTCGGAGG	PRPF4B	ENSG00000112739	-1.209415700028249	[277]	[76]	-6	hSpCas9	negative selection	11741981
4040786	4040809	6	+	28162770	MV411	viability	GGAGCAGATCACGCTTGCGAAGG	PRPF4B	ENSG00000112739	-0.2340953602829754	[147]	[105]	-2	hSpCas9	negative selection	11911338
4049032	4049055	6	-	28162770	MV411	viability	GAAATCTTTTCCAATGCCAGCGG	PRPF4B	ENSG00000112739	0.005573844824592111	[459]	[388]	0	hSpCas9	negative selection	11911339
4040806	4040829	6	+	28162770	MV411	viability	AGGCGGTCTCGATCACGCGGTGG	PRPF4B	ENSG00000112739	-1.9620158148461744	[73]	[15]	-8	hSpCas9	negative selection	11911340
4021416	4021439	6	+	28162770	MV411	viability	GAAGTTCAAGATGGCCGCCGCGG	PRPF4B	ENSG00000112739	-0.003694765994726887	[168]	[141]	0	hSpCas9	negative selection	11911341
4021430	4021453	6	-	28162770	MV411	viability	TAGCGACTGGGTCTCCGCGGCGG	PRPF4B	ENSG00000112739	-1.1675999484960684	[71]	[26]	-6	hSpCas9	negative selection	11911342
4032661	4032684	6	-	28162770	MV411	viability	CCAGGAGACAGTGTCCGCGAGGG	PRPF4B	ENSG00000112739	-2.042069066412209	[175]	[35]	-8	hSpCas9	negative selection	11911343
4031937	4031960	6	+	28162770	MV411	viability	TGAGTCTGGCTCTGAAGAAGAGG	PRPF4B	ENSG00000112739	-0.42114106840318066	[514]	[323]	-3	hSpCas9	negative selection	11911344
4032241	4032264	6	-	28162770	MV411	viability	TGAGATCGCCTTCTAAGGGTAGG	PRPF4B	ENSG00000112739	-0.46876948321663336	[137]	[83]	-3	hSpCas9	negative selection	11911345
4032713	4032736	6	+	28162770	MV411	viability	GAAAACGACGAGAACCAGAGAGG	PRPF4B	ENSG00000112739	0.610007630167483	[6]	[8]	5	hSpCas9	negative selection	11911346
4040765	4040788	6	+	28162770	MV411	viability	TAAATAGGGACAGAGGTCGGAGG	PRPF4B	ENSG00000112739	-0.19085530079637153	[270]	[199]	-1	hSpCas9	negative selection	11911347
4040786	4040809	6	+	28162770	MONOMAC1	viability	GGAGCAGATCACGCTTGCGAAGG	PRPF4B	ENSG00000112739	0.20092713886034874	[84]	[111]	2	hSpCas9	negative selection	12080704
4049032	4049055	6	-	28162770	MONOMAC1	viability	GAAATCTTTTCCAATGCCAGCGG	PRPF4B	ENSG00000112739	-0.4332117928274052	[297]	[252]	-4	hSpCas9	negative selection	12080705
4040806	4040829	6	+	28162770	MONOMAC1	viability	AGGCGGTCTCGATCACGCGGTGG	PRPF4B	ENSG00000112739	-2.1039274426680725	[59]	[15]	-9	hSpCas9	negative selection	12080706
4021416	4021439	6	+	28162770	MONOMAC1	viability	GAAGTTCAAGATGGCCGCCGCGG	PRPF4B	ENSG00000112739	0.0974105114057016	[105]	[129]	1	hSpCas9	negative selection	12080707
4021430	4021453	6	-	28162770	MONOMAC1	viability	TAGCGACTGGGTCTCCGCGGCGG	PRPF4B	ENSG00000112739	0.22565422476272534	[46]	[62]	2	hSpCas9	negative selection	12080708
4032661	4032684	6	-	28162770	MONOMAC1	viability	CCAGGAGACAGTGTCCGCGAGGG	PRPF4B	ENSG00000112739	-1.3190273714381642	[73]	[33]	-7	hSpCas9	negative selection	12080709
4031937	4031960	6	+	28162770	MONOMAC1	viability	TGAGTCTGGCTCTGAAGAAGAGG	PRPF4B	ENSG00000112739	-1.0248558716768734	[283]	[159]	-7	hSpCas9	negative selection	12080710
4032241	4032264	6	-	28162770	MONOMAC1	viability	TGAGATCGCCTTCTAAGGGTAGG	PRPF4B	ENSG00000112739	-1.4470151000679012	[87]	[36]	-8	hSpCas9	negative selection	12080711
4032713	4032736	6	+	28162770	MONOMAC1	viability	GAAAACGACGAGAACCAGAGAGG	PRPF4B	ENSG00000112739	-1.1299226512010168	[20]	[10]	-7	hSpCas9	negative selection	12080712
4040765	4040788	6	+	28162770	MONOMAC1	viability	TAAATAGGGACAGAGGTCGGAGG	PRPF4B	ENSG00000112739	-1.3097369798089158	[172]	[79]	-7	hSpCas9	negative selection	12080713
4040786	4040809	6	+	28162770	OCIAML2	viability	GGAGCAGATCACGCTTGCGAAGG	PRPF4B	ENSG00000112739	-0.591484220116547	[27]	[102]	-4	hSpCas9	negative selection	12250070
4049032	4049055	6	-	28162770	OCIAML2	viability	GAAATCTTTTCCAATGCCAGCGG	PRPF4B	ENSG00000112739	-0.4860598658117671	[93]	[371]	-4	hSpCas9	negative selection	12250071
4040806	4040829	6	+	28162770	OCIAML2	viability	AGGCGGTCTCGATCACGCGGTGG	PRPF4B	ENSG00000112739	-1.3007048237998486	[15]	[35]	-7	hSpCas9	negative selection	12250072
4021416	4021439	6	+	28162770	OCIAML2	viability	GAAGTTCAAGATGGCCGCCGCGG	PRPF4B	ENSG00000112739	0.6681342447136905	[25]	[228]	6	hSpCas9	negative selection	12250073
4021430	4021453	6	-	28162770	OCIAML2	viability	TAGCGACTGGGTCTCCGCGGCGG	PRPF4B	ENSG00000112739	-0.3737682859895721	[17]	[76]	-3	hSpCas9	negative selection	12250074
4032661	4032684	6	-	28162770	OCIAML2	viability	CCAGGAGACAGTGTCCGCGAGGG	PRPF4B	ENSG00000112739	-0.3860963150304936	[28]	[122]	-3	hSpCas9	negative selection	12250075
4031937	4031960	6	+	28162770	OCIAML2	viability	TGAGTCTGGCTCTGAAGAAGAGG	PRPF4B	ENSG00000112739	0.03572284078262866	[87]	[499]	0	hSpCas9	negative selection	12250076
4032241	4032264	6	-	28162770	OCIAML2	viability	TGAGATCGCCTTCTAAGGGTAGG	PRPF4B	ENSG00000112739	-1.4200037521721933	[27]	[57]	-7	hSpCas9	negative selection	12250077
4032713	4032736	6	+	28162770	OCIAML2	viability	GAAAACGACGAGAACCAGAGAGG	PRPF4B	ENSG00000112739	-3.2075954194083676	[9]	[5]	-9	hSpCas9	negative selection	12250078
4040765	4040788	6	+	28162770	OCIAML2	viability	TAAATAGGGACAGAGGTCGGAGG	PRPF4B	ENSG00000112739	-0.9831838304352671	[50]	[142]	-6	hSpCas9	negative selection	12250079
4040786	4040809	6	+	28162770	OCIAML3	viability	GGAGCAGATCACGCTTGCGAAGG	PRPF4B	ENSG00000112739	-0.49091414736005967	[26]	[57]	-4	hSpCas9	negative selection	12419436
4049032	4049055	6	-	28162770	OCIAML3	viability	GAAATCTTTTCCAATGCCAGCGG	PRPF4B	ENSG00000112739	-0.43773170039370213	[117]	[262]	-3	hSpCas9	negative selection	12419437
4040806	4040829	6	+	28162770	OCIAML3	viability	AGGCGGTCTCGATCACGCGGTGG	PRPF4B	ENSG00000112739	-0.8164000616606111	[13]	[23]	-6	hSpCas9	negative selection	12419438
4021416	4021439	6	+	28162770	OCIAML3	viability	GAAGTTCAAGATGGCCGCCGCGG	PRPF4B	ENSG00000112739	-0.690683659735837	[53]	[100]	-5	hSpCas9	negative selection	12419439
4021430	4021453	6	-	28162770	OCIAML3	viability	TAGCGACTGGGTCTCCGCGGCGG	PRPF4B	ENSG00000112739	-0.5351139512705947	[23]	[49]	-4	hSpCas9	negative selection	12419440
4032661	4032684	6	-	28162770	OCIAML3	viability	CCAGGAGACAGTGTCCGCGAGGG	PRPF4B	ENSG00000112739	-0.8034610059531127	[36]	[63]	-5	hSpCas9	negative selection	12419441
4031937	4031960	6	+	28162770	OCIAML3	viability	TGAGTCTGGCTCTGAAGAAGAGG	PRPF4B	ENSG00000112739	-0.8854704544844745	[163]	[267]	-6	hSpCas9	negative selection	12419442
4032241	4032264	6	-	28162770	OCIAML3	viability	TGAGATCGCCTTCTAAGGGTAGG	PRPF4B	ENSG00000112739	-1.7143018740418752	[49]	[45]	-8	hSpCas9	negative selection	12419443
4032713	4032736	6	+	28162770	OCIAML3	viability	GAAAACGACGAGAACCAGAGAGG	PRPF4B	ENSG00000112739	-0.6935433138750777	[14]	[27]	-5	hSpCas9	negative selection	12419444
4040765	4040788	6	+	28162770	OCIAML3	viability	TAAATAGGGACAGAGGTCGGAGG	PRPF4B	ENSG00000112739	-0.8302419868142417	[95]	[162]	-6	hSpCas9	negative selection	12419445