Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:5630
• Symbol:PRPH
• Description:peripherin

DataSource: http://genomecrispr.dkfz.de/#!/results/PRPH

Export (tab separated) Export to Excel

Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
49295251	49295274	12	-	26472758	Jiyoye	viability	GCGGTGGACCGAAGGTACGGCGG	PRPH	ENSG00000135406	0.04460530212116531	[71]	[55]	0	hSpCas9	negative selection	128145
49296950	49296973	12	-	26472758	Jiyoye	viability	CGTCAGCTCGGGCTTCACCGTGG	PRPH	ENSG00000135406	0.3376344482527964	[84]	[80]	2	hSpCas9	negative selection	128146
49297017	49297040	12	+	26472758	Jiyoye	viability	GAAGAACCTGCAGGAGGCGGAGG	PRPH	ENSG00000135406	-1.2405228745632455	[281]	[89]	-7	hSpCas9	negative selection	128147
49295241	49295264	12	-	26472758	Jiyoye	viability	GAAGGTACGGCGGTATGAGGTGG	PRPH	ENSG00000135406	1.079600723477369	[63]	[101]	7	hSpCas9	negative selection	128148
49295292	49295315	12	-	26472758	Jiyoye	viability	GGAGCTGGACGAGTAGGAGAAGG	PRPH	ENSG00000135406	-0.6802874597444659	[118]	[55]	-5	hSpCas9	negative selection	128149
49295358	49295381	12	-	26472758	Jiyoye	viability	GAAGCTGCCCAGGCGCACCGAGG	PRPH	ENSG00000135406	-0.48898880750958673	[133]	[71]	-4	hSpCas9	negative selection	128150
49295420	49295443	12	-	26472758	Jiyoye	viability	GAGAAGTCGAGGCGCTCCGAGGG	PRPH	ENSG00000135406	-0.5767049531308496	[88]	[44]	-4	hSpCas9	negative selection	128151
49295579	49295602	12	+	26472758	Jiyoye	viability	GGGGAGCTGAGCCAAGCCCGGGG	PRPH	ENSG00000135406	-1.3875057105166202	[169]	[48]	-7	hSpCas9	negative selection	128152
49296184	49296207	12	+	26472758	Jiyoye	viability	GGAGGAGACGCGCAAGCGGGAGG	PRPH	ENSG00000135406	1.9463341926139048	[31]	[92]	8	hSpCas9	negative selection	128153
49296933	49296956	12	+	26472758	Jiyoye	viability	GCAGGTGGAGGTGGAAGCCACGG	PRPH	ENSG00000135406	-2.956572889076116	[174]	[16]	-9	hSpCas9	negative selection	128154
49295251	49295274	12	-	26472758	KBM7	viability	GCGGTGGACCGAAGGTACGGCGG	PRPH	ENSG00000135406	-0.33087043414916106	[322,219]	[127,74]	-3	hSpCas9	negative selection	319263
49296950	49296973	12	-	26472758	KBM7	viability	CGTCAGCTCGGGCTTCACCGTGG	PRPH	ENSG00000135406	0.375567501683867	[374,269]	[148,234]	4	hSpCas9	negative selection	319264
49297017	49297040	12	+	26472758	KBM7	viability	GAAGAACCTGCAGGAGGCGGAGG	PRPH	ENSG00000135406	-0.6099158922857177	[386,296]	[142,69]	-5	hSpCas9	negative selection	319265
49295241	49295264	12	-	26472758	KBM7	viability	GAAGGTACGGCGGTATGAGGTGG	PRPH	ENSG00000135406	-0.41999069316352633	[797,751]	[284,261]	-4	hSpCas9	negative selection	319266
49295292	49295315	12	-	26472758	KBM7	viability	GGAGCTGGACGAGTAGGAGAAGG	PRPH	ENSG00000135406	-0.07830120070357904	[156,201]	[102,61]	-1	hSpCas9	negative selection	319267
49295358	49295381	12	-	26472758	KBM7	viability	GAAGCTGCCCAGGCGCACCGAGG	PRPH	ENSG00000135406	1.0116104108406205	[382,162]	[326,179]	9	hSpCas9	negative selection	319268
49295420	49295443	12	-	26472758	KBM7	viability	GAGAAGTCGAGGCGCTCCGAGGG	PRPH	ENSG00000135406	-0.34395649388844707	[450,356]	[155,141]	-3	hSpCas9	negative selection	319269
49295579	49295602	12	+	26472758	KBM7	viability	GGGGAGCTGAGCCAAGCCCGGGG	PRPH	ENSG00000135406	-0.5653667407304588	[363,195]	[73,97]	-5	hSpCas9	negative selection	319270
49296184	49296207	12	+	26472758	KBM7	viability	GGAGGAGACGCGCAAGCGGGAGG	PRPH	ENSG00000135406	-0.4688372821422304	[248,263]	[109,67]	-4	hSpCas9	negative selection	319271
49296933	49296956	12	+	26472758	KBM7	viability	GCAGGTGGAGGTGGAAGCCACGG	PRPH	ENSG00000135406	-2.157604150413914	[680,562]	[41,85]	-8	hSpCas9	negative selection	319272
49295251	49295274	12	-	26472758	Raji	viability	GCGGTGGACCGAAGGTACGGCGG	PRPH	ENSG00000135406	0.5493880822527127	[105]	[35]	5	hSpCas9	negative selection	510381
49296950	49296973	12	-	26472758	Raji	viability	CGTCAGCTCGGGCTTCACCGTGG	PRPH	ENSG00000135406	-0.24849189143710046	[214]	[41]	-2	hSpCas9	negative selection	510382
49297017	49297040	12	+	26472758	Raji	viability	GAAGAACCTGCAGGAGGCGGAGG	PRPH	ENSG00000135406	-0.7146181626484062	[197]	[27]	-5	hSpCas9	negative selection	510383
49295241	49295264	12	-	26472758	Raji	viability	GAAGGTACGGCGGTATGAGGTGG	PRPH	ENSG00000135406	-0.014245909027931672	[234]	[53]	0	hSpCas9	negative selection	510384
49295292	49295315	12	-	26472758	Raji	viability	GGAGCTGGACGAGTAGGAGAAGG	PRPH	ENSG00000135406	-0.5466206097772079	[106]	[16]	-4	hSpCas9	negative selection	510385
49295358	49295381	12	-	26472758	Raji	viability	GAAGCTGCCCAGGCGCACCGAGG	PRPH	ENSG00000135406	0.3315986923168651	[112]	[32]	3	hSpCas9	negative selection	510386
49295420	49295443	12	-	26472758	Raji	viability	GAGAAGTCGAGGCGCTCCGAGGG	PRPH	ENSG00000135406	-1.15063279569357	[286]	[29]	-7	hSpCas9	negative selection	510387
49295579	49295602	12	+	26472758	Raji	viability	GGGGAGCTGAGCCAAGCCCGGGG	PRPH	ENSG00000135406	-0.008093682046336315	[155]	[35]	0	hSpCas9	negative selection	510388
49296184	49296207	12	+	26472758	Raji	viability	GGAGGAGACGCGCAAGCGGGAGG	PRPH	ENSG00000135406	-1.3694301614919344	[166]	[14]	-7	hSpCas9	negative selection	510389
49296933	49296956	12	+	26472758	Raji	viability	GCAGGTGGAGGTGGAAGCCACGG	PRPH	ENSG00000135406	-2.2711280878801303	[311]	[14]	-9	hSpCas9	negative selection	510390
49295251	49295274	12	-	26472758	K562	viability	GCGGTGGACCGAAGGTACGGCGG	PRPH	ENSG00000135406	0.4676521254422657	[244]	[285]	4	hSpCas9	negative selection	701499
49296950	49296973	12	-	26472758	K562	viability	CGTCAGCTCGGGCTTCACCGTGG	PRPH	ENSG00000135406	-0.14677202965802938	[319]	[243]	-1	hSpCas9	negative selection	701500
49297017	49297040	12	+	26472758	K562	viability	GAAGAACCTGCAGGAGGCGGAGG	PRPH	ENSG00000135406	0.48639151797241104	[229]	[271]	4	hSpCas9	negative selection	701501
49295241	49295264	12	-	26472758	K562	viability	GAAGGTACGGCGGTATGAGGTGG	PRPH	ENSG00000135406	0.2058654868970538	[492]	[479]	1	hSpCas9	negative selection	701502
49295292	49295315	12	-	26472758	K562	viability	GGAGCTGGACGAGTAGGAGAAGG	PRPH	ENSG00000135406	-0.3680245094768164	[158]	[103]	-2	hSpCas9	negative selection	701503
49295358	49295381	12	-	26472758	K562	viability	GAAGCTGCCCAGGCGCACCGAGG	PRPH	ENSG00000135406	0.48849204441584576	[216]	[256]	4	hSpCas9	negative selection	701504
49295420	49295443	12	-	26472758	K562	viability	GAGAAGTCGAGGCGCTCCGAGGG	PRPH	ENSG00000135406	-0.7701540734208255	[397]	[196]	-4	hSpCas9	negative selection	701505
49295579	49295602	12	+	26472758	K562	viability	GGGGAGCTGAGCCAAGCCCGGGG	PRPH	ENSG00000135406	-0.9892536185360036	[213]	[90]	-5	hSpCas9	negative selection	701506
49296184	49296207	12	+	26472758	K562	viability	GGAGGAGACGCGCAAGCGGGAGG	PRPH	ENSG00000135406	0.887262144468103	[170]	[266]	7	hSpCas9	negative selection	701507
49296933	49296956	12	+	26472758	K562	viability	GCAGGTGGAGGTGGAAGCCACGG	PRPH	ENSG00000135406	-4.465239520504024	[470]	[17]	-9	hSpCas9	negative selection	701508
49295475	49295498	12	-	26627737	DLD1	viability	CTGCTTCTCGTTGCTGCGCGTGG	PRPH	ENSG00000135406	-0.06054323810431561	[1026]	[467,296,177]	0	hSpCas9	negative selection	783950
49296217	49296240	12	+	26627737	DLD1	viability	CAACCTCGTGCTCTTCCGCAAGG	PRPH	ENSG00000135406	0.2819798021013414	[459]	[162,279,97]	3	hSpCas9	negative selection	783951
49296455	49296478	12	-	26627737	DLD1	viability	TCTTGCGCTCTAGTTCCAGGCGG	PRPH	ENSG00000135406	1.0719377941160726	[182]	[86,158,116]	8	hSpCas9	negative selection	783952
49296990	49297013	12	-	26627737	DLD1	viability	CGATGCTCTCGTACTGCGCGCGG	PRPH	ENSG00000135406	0.7163646420272414	[316]	[216,158,118]	7	hSpCas9	negative selection	783953
49297234	49297257	12	+	26627737	DLD1	viability	CCAGAGTCTAACGTGCGAGGTGG	PRPH	ENSG00000135406	0.6208253075717522	[977]	[363,689,379]	6	hSpCas9	negative selection	783954
49297368	49297391	12	+	26627737	DLD1	viability	GCTCAGGCAGTTGAGAGAGCTGG	PRPH	ENSG00000135406	0.7728598337931607	[323]	[239,253,47]	7	hSpCas9	negative selection	783955
49295475	49295498	12	-	26627737	GBM cells	viability after 5 days	CTGCTTCTCGTTGCTGCGCGTGG	PRPH	ENSG00000135406	0.3228139428743254	[283]	[199,180]	5	hSpCas9	negative selection	866265
49296217	49296240	12	+	26627737	GBM cells	viability after 5 days	CAACCTCGTGCTCTTCCGCAAGG	PRPH	ENSG00000135406	0.27016968213661635	[275]	[166,189]	4	hSpCas9	negative selection	866266
49296455	49296478	12	-	26627737	GBM cells	viability after 5 days	TCTTGCGCTCTAGTTCCAGGCGG	PRPH	ENSG00000135406	-0.3924259001682536	[174]	[63,78]	-6	hSpCas9	negative selection	866267
49296990	49297013	12	-	26627737	GBM cells	viability after 5 days	CGATGCTCTCGTACTGCGCGCGG	PRPH	ENSG00000135406	-0.24842784118950134	[102]	[47,44]	-4	hSpCas9	negative selection	866268
49297234	49297257	12	+	26627737	GBM cells	viability after 5 days	CCAGAGTCTAACGTGCGAGGTGG	PRPH	ENSG00000135406	-1.0687856332110044	[529]	[152,117]	-9	hSpCas9	negative selection	866269
49297368	49297391	12	+	26627737	GBM cells	viability after 5 days	GCTCAGGCAGTTGAGAGAGCTGG	PRPH	ENSG00000135406	-0.2357356518090964	[201]	[94,88]	-4	hSpCas9	negative selection	866270
49295475	49295498	12	-	26627737	GBM cells	viability after 13 days	CTGCTTCTCGTTGCTGCGCGTGG	PRPH	ENSG00000135406	0.7684487911116186	[283]	[267,257]	8	hSpCas9	negative selection	948580
49296217	49296240	12	+	26627737	GBM cells	viability after 13 days	CAACCTCGTGCTCTTCCGCAAGG	PRPH	ENSG00000135406	0.35228433901520534	[275]	[183,196]	4	hSpCas9	negative selection	948581
49296455	49296478	12	-	26627737	GBM cells	viability after 13 days	TCTTGCGCTCTAGTTCCAGGCGG	PRPH	ENSG00000135406	-0.4793070312507526	[174]	[82,55]	-5	hSpCas9	negative selection	948582
49296990	49297013	12	-	26627737	GBM cells	viability after 13 days	CGATGCTCTCGTACTGCGCGCGG	PRPH	ENSG00000135406	0.23403748690521775	[102]	[73,58]	3	hSpCas9	negative selection	948583
49297234	49297257	12	+	26627737	GBM cells	viability after 13 days	CCAGAGTCTAACGTGCGAGGTGG	PRPH	ENSG00000135406	-1.2959307614019508	[529]	[72,152]	-8	hSpCas9	negative selection	948584
49297368	49297391	12	+	26627737	GBM cells	viability after 13 days	GCTCAGGCAGTTGAGAGAGCTGG	PRPH	ENSG00000135406	-0.9413584826382387	[201]	[66,48]	-8	hSpCas9	negative selection	948585
49295475	49295498	12	-	26627737	GBM cells	viability after 21 days	CTGCTTCTCGTTGCTGCGCGTGG	PRPH	ENSG00000135406	1.0079544063208057	[283]	[326,294]	8	hSpCas9	negative selection	1030895
49296217	49296240	12	+	26627737	GBM cells	viability after 21 days	CAACCTCGTGCTCTTCCGCAAGG	PRPH	ENSG00000135406	0.2672974194439348	[275]	[192,168]	3	hSpCas9	negative selection	1030896
49296455	49296478	12	-	26627737	GBM cells	viability after 21 days	TCTTGCGCTCTAGTTCCAGGCGG	PRPH	ENSG00000135406	0.38876658771204603	[174]	[124,123]	4	hSpCas9	negative selection	1030897
49296990	49297013	12	-	26627737	GBM cells	viability after 21 days	CGATGCTCTCGTACTGCGCGCGG	PRPH	ENSG00000135406	-0.21730279628890758	[102]	[44,50]	-2	hSpCas9	negative selection	1030898
49297234	49297257	12	+	26627737	GBM cells	viability after 21 days	CCAGAGTCTAACGTGCGAGGTGG	PRPH	ENSG00000135406	-0.9560519472818793	[529]	[161,135]	-7	hSpCas9	negative selection	1030899
49297368	49297391	12	+	26627737	GBM cells	viability after 21 days	GCTCAGGCAGTTGAGAGAGCTGG	PRPH	ENSG00000135406	-0.8764408220218246	[201]	[64,54]	-6	hSpCas9	negative selection	1030900
49295475	49295498	12	-	26627737	RPE1	viability after 9 days	CTGCTTCTCGTTGCTGCGCGTGG	PRPH	ENSG00000135406	0.21143838736385412	[1342]	[395,603]	1	hSpCas9	negative selection	1113210
49296217	49296240	12	+	26627737	RPE1	viability after 9 days	CAACCTCGTGCTCTTCCGCAAGG	PRPH	ENSG00000135406	0.7914329662448869	[444]	[303,159]	5	hSpCas9	negative selection	1113211
49296455	49296478	12	-	26627737	RPE1	viability after 9 days	TCTTGCGCTCTAGTTCCAGGCGG	PRPH	ENSG00000135406	-0.0491435549359876	[605]	[147,228]	0	hSpCas9	negative selection	1113212
49296990	49297013	12	-	26627737	RPE1	viability after 9 days	CGATGCTCTCGTACTGCGCGCGG	PRPH	ENSG00000135406	0.725764272324448	[124]	[17,124]	5	hSpCas9	negative selection	1113213
49297234	49297257	12	+	26627737	RPE1	viability after 9 days	CCAGAGTCTAACGTGCGAGGTGG	PRPH	ENSG00000135406	-0.350440460090517	[1781]	[382,507]	-2	hSpCas9	negative selection	1113214
49297368	49297391	12	+	26627737	RPE1	viability after 9 days	GCTCAGGCAGTTGAGAGAGCTGG	PRPH	ENSG00000135406	1.9907071109965695	[178]	[144,322]	8	hSpCas9	negative selection	1113215
49295475	49295498	12	-	26627737	RPE1	viability after 12 days	CTGCTTCTCGTTGCTGCGCGTGG	PRPH	ENSG00000135406	0.09133234813208346	[1342]	[414,351]	0	hSpCas9	negative selection	1195525
49296217	49296240	12	+	26627737	RPE1	viability after 12 days	CAACCTCGTGCTCTTCCGCAAGG	PRPH	ENSG00000135406	0.3849086371645018	[444]	[176,133]	2	hSpCas9	negative selection	1195526
49296455	49296478	12	-	26627737	RPE1	viability after 12 days	TCTTGCGCTCTAGTTCCAGGCGG	PRPH	ENSG00000135406	0.2445399148489454	[605]	[171,214]	1	hSpCas9	negative selection	1195527
49296990	49297013	12	-	26627737	RPE1	viability after 12 days	CGATGCTCTCGTACTGCGCGCGG	PRPH	ENSG00000135406	0.9982608031761371	[124]	[52,81]	6	hSpCas9	negative selection	1195528
49297234	49297257	12	+	26627737	RPE1	viability after 12 days	CCAGAGTCTAACGTGCGAGGTGG	PRPH	ENSG00000135406	-0.5763555418295492	[1781]	[255,389]	-4	hSpCas9	negative selection	1195529
49297368	49297391	12	+	26627737	RPE1	viability after 12 days	GCTCAGGCAGTTGAGAGAGCTGG	PRPH	ENSG00000135406	1.8731317915710899	[178]	[164,187]	8	hSpCas9	negative selection	1195530
49295475	49295498	12	-	26627737	RPE1	viability after 15 days	CTGCTTCTCGTTGCTGCGCGTGG	PRPH	ENSG00000135406	-0.47811318201222447	[1342]	[202,339]	-3	hSpCas9	negative selection	1277840
49296217	49296240	12	+	26627737	RPE1	viability after 15 days	CAACCTCGTGCTCTTCCGCAAGG	PRPH	ENSG00000135406	0.6873636970853124	[444]	[218,186]	4	hSpCas9	negative selection	1277841
49296455	49296478	12	-	26627737	RPE1	viability after 15 days	TCTTGCGCTCTAGTTCCAGGCGG	PRPH	ENSG00000135406	-0.14214543214786907	[605]	[79,227]	-1	hSpCas9	negative selection	1277842
49296990	49297013	12	-	26627737	RPE1	viability after 15 days	CGATGCTCTCGTACTGCGCGCGG	PRPH	ENSG00000135406	1.0203027598992565	[124]	[2,137]	6	hSpCas9	negative selection	1277843
49297234	49297257	12	+	26627737	RPE1	viability after 15 days	CCAGAGTCTAACGTGCGAGGTGG	PRPH	ENSG00000135406	-0.6570844186159827	[1781]	[309,328]	-4	hSpCas9	negative selection	1277844
49297368	49297391	12	+	26627737	RPE1	viability after 15 days	GCTCAGGCAGTTGAGAGAGCTGG	PRPH	ENSG00000135406	2.3076809749534797	[178]	[211,287]	9	hSpCas9	negative selection	1277845
49295475	49295498	12	-	26627737	RPE1	viability after 18 days	CTGCTTCTCGTTGCTGCGCGTGG	PRPH	ENSG00000135406	0.17033040944108935	[1342]	[490,318]	1	hSpCas9	negative selection	1360155
49296217	49296240	12	+	26627737	RPE1	viability after 18 days	CAACCTCGTGCTCTTCCGCAAGG	PRPH	ENSG00000135406	0.09983778835136048	[444]	[148,106]	0	hSpCas9	negative selection	1360156
49296455	49296478	12	-	26627737	RPE1	viability after 18 days	TCTTGCGCTCTAGTTCCAGGCGG	PRPH	ENSG00000135406	-0.2302424071407438	[605]	[136,141]	-1	hSpCas9	negative selection	1360157
49296990	49297013	12	-	26627737	RPE1	viability after 18 days	CGATGCTCTCGTACTGCGCGCGG	PRPH	ENSG00000135406	1.869508097558169	[124]	[28,223]	8	hSpCas9	negative selection	1360158
49297234	49297257	12	+	26627737	RPE1	viability after 18 days	CCAGAGTCTAACGTGCGAGGTGG	PRPH	ENSG00000135406	-0.6637340280562476	[1781]	[290,316]	-4	hSpCas9	negative selection	1360159
49297368	49297391	12	+	26627737	RPE1	viability after 18 days	GCTCAGGCAGTTGAGAGAGCTGG	PRPH	ENSG00000135406	1.9511006359651943	[178]	[165,208]	8	hSpCas9	negative selection	1360160
49295475	49295498	12	-	26627737	HeLa	viability after 8 days	CTGCTTCTCGTTGCTGCGCGTGG	PRPH	ENSG00000135406	-0.383653085043443	[553]	[182,201,169]	-4	hSpCas9	negative selection	1442470
49296217	49296240	12	+	26627737	HeLa	viability after 8 days	CAACCTCGTGCTCTTCCGCAAGG	PRPH	ENSG00000135406	-0.29125669899364176	[488]	[429,47,104]	-3	hSpCas9	negative selection	1442471
49296455	49296478	12	-	26627737	HeLa	viability after 8 days	TCTTGCGCTCTAGTTCCAGGCGG	PRPH	ENSG00000135406	-0.45710975228386663	[228]	[150,25,58]	-4	hSpCas9	negative selection	1442472
49296990	49297013	12	-	26627737	HeLa	viability after 8 days	CGATGCTCTCGTACTGCGCGCGG	PRPH	ENSG00000135406	-2.157081226739261	[227]	[70,6,0]	-9	hSpCas9	negative selection	1442473
49297234	49297257	12	+	26627737	HeLa	viability after 8 days	CCAGAGTCTAACGTGCGAGGTGG	PRPH	ENSG00000135406	-1.1943680644393337	[744]	[68,168,168]	-8	hSpCas9	negative selection	1442474
49297368	49297391	12	+	26627737	HeLa	viability after 8 days	GCTCAGGCAGTTGAGAGAGCTGG	PRPH	ENSG00000135406	-0.5924378055337247	[471]	[109,202,92]	-5	hSpCas9	negative selection	1442475
49295475	49295498	12	-	26627737	HeLa	viability after 12 days	CTGCTTCTCGTTGCTGCGCGTGG	PRPH	ENSG00000135406	0.6289793854871479	[553]	[506,293,271]	5	hSpCas9	negative selection	1524785
49296217	49296240	12	+	26627737	HeLa	viability after 12 days	CAACCTCGTGCTCTTCCGCAAGG	PRPH	ENSG00000135406	-1.1207769439084179	[488]	[51,107,115]	-8	hSpCas9	negative selection	1524786
49296455	49296478	12	-	26627737	HeLa	viability after 12 days	TCTTGCGCTCTAGTTCCAGGCGG	PRPH	ENSG00000135406	-1.165498707656897	[228]	[14,58,49]	-8	hSpCas9	negative selection	1524787
49296990	49297013	12	-	26627737	HeLa	viability after 12 days	CGATGCTCTCGTACTGCGCGCGG	PRPH	ENSG00000135406	-0.08941213760802746	[227]	[89,85,89]	0	hSpCas9	negative selection	1524788
49297234	49297257	12	+	26627737	HeLa	viability after 12 days	CCAGAGTCTAACGTGCGAGGTGG	PRPH	ENSG00000135406	-0.4880226549123025	[744]	[133,257,259]	-4	hSpCas9	negative selection	1524789
49297368	49297391	12	+	26627737	HeLa	viability after 12 days	GCTCAGGCAGTTGAGAGAGCTGG	PRPH	ENSG00000135406	-0.09677561369385082	[471]	[241,247,51]	-1	hSpCas9	negative selection	1524790
49295475	49295498	12	-	26627737	HeLa	viability after 15 days	CTGCTTCTCGTTGCTGCGCGTGG	PRPH	ENSG00000135406	0.18312667173949548	[553]	[171,283,317]	1	hSpCas9	negative selection	1607100
49296217	49296240	12	+	26627737	HeLa	viability after 15 days	CAACCTCGTGCTCTTCCGCAAGG	PRPH	ENSG00000135406	-0.5635712273918805	[488]	[115,48,247]	-5	hSpCas9	negative selection	1607101
49296455	49296478	12	-	26627737	HeLa	viability after 15 days	TCTTGCGCTCTAGTTCCAGGCGG	PRPH	ENSG00000135406	-1.904344135682046	[228]	[15,55,0]	-9	hSpCas9	negative selection	1607102
49296990	49297013	12	-	26627737	HeLa	viability after 15 days	CGATGCTCTCGTACTGCGCGCGG	PRPH	ENSG00000135406	-3.5007557307116204	[227]	[11,10,0]	-9	hSpCas9	negative selection	1607103
49297234	49297257	12	+	26627737	HeLa	viability after 15 days	CCAGAGTCTAACGTGCGAGGTGG	PRPH	ENSG00000135406	-0.9516604680757438	[744]	[196,90,183]	-7	hSpCas9	negative selection	1607104
49297368	49297391	12	+	26627737	HeLa	viability after 15 days	GCTCAGGCAGTTGAGAGAGCTGG	PRPH	ENSG00000135406	-0.7856085037046762	[471]	[230,24,73]	-6	hSpCas9	negative selection	1607105
49295475	49295498	12	-	26627737	HeLa	viability after 18 days	CTGCTTCTCGTTGCTGCGCGTGG	PRPH	ENSG00000135406	0.1815795522506658	[553]	[114,234,317]	1	hSpCas9	negative selection	1689415
49296217	49296240	12	+	26627737	HeLa	viability after 18 days	CAACCTCGTGCTCTTCCGCAAGG	PRPH	ENSG00000135406	-0.5432908201241017	[488]	[81,39,247]	-5	hSpCas9	negative selection	1689416
49296455	49296478	12	-	26627737	HeLa	viability after 18 days	TCTTGCGCTCTAGTTCCAGGCGG	PRPH	ENSG00000135406	-1.9912201038893373	[228]	[8,44,0]	-9	hSpCas9	negative selection	1689417
49296990	49297013	12	-	26627737	HeLa	viability after 18 days	CGATGCTCTCGTACTGCGCGCGG	PRPH	ENSG00000135406	-3.6876736518442015	[227]	[6,7,0]	-9	hSpCas9	negative selection	1689418
49297234	49297257	12	+	26627737	HeLa	viability after 18 days	CCAGAGTCTAACGTGCGAGGTGG	PRPH	ENSG00000135406	-0.956687006589885	[744]	[132,72,183]	-7	hSpCas9	negative selection	1689419
49297368	49297391	12	+	26627737	HeLa	viability after 18 days	GCTCAGGCAGTTGAGAGAGCTGG	PRPH	ENSG00000135406	-0.7641709126841291	[471]	[157,20,73]	-6	hSpCas9	negative selection	1689420
49295475	49295498	12	-	26627737	HCT116	viability after 6 days	CTGCTTCTCGTTGCTGCGCGTGG	PRPH	ENSG00000135406	-0.23070332889929562	[546]	[100,57]	-1	hSpCas9	negative selection	1771730
49296217	49296240	12	+	26627737	HCT116	viability after 6 days	CAACCTCGTGCTCTTCCGCAAGG	PRPH	ENSG00000135406	1.3791530966562244	[371]	[378,26]	7	hSpCas9	negative selection	1771731
49296455	49296478	12	-	26627737	HCT116	viability after 6 days	TCTTGCGCTCTAGTTCCAGGCGG	PRPH	ENSG00000135406	-0.850750251105305	[373]	[20,38]	-5	hSpCas9	negative selection	1771732
49296990	49297013	12	-	26627737	HCT116	viability after 6 days	CGATGCTCTCGTACTGCGCGCGG	PRPH	ENSG00000135406	1.6071568200000763	[436]	[178,225]	8	hSpCas9	negative selection	1771733
49297234	49297257	12	+	26627737	HCT116	viability after 6 days	CCAGAGTCTAACGTGCGAGGTGG	PRPH	ENSG00000135406	-0.39374172616824665	[1499]	[319,101]	-2	hSpCas9	negative selection	1771734
49297368	49297391	12	+	26627737	HCT116	viability after 6 days	GCTCAGGCAGTTGAGAGAGCTGG	PRPH	ENSG00000135406	-1.1887371347172482	[833]	[23,75]	-6	hSpCas9	negative selection	1771735
49295475	49295498	12	-	26627737	HCT116	viability after 8 days	CTGCTTCTCGTTGCTGCGCGTGG	PRPH	ENSG00000135406	0.6875810320819329	[203]	[176,179,185]	6	hSpCas9	negative selection	1854045
49296217	49296240	12	+	26627737	HCT116	viability after 8 days	CAACCTCGTGCTCTTCCGCAAGG	PRPH	ENSG00000135406	-0.6470021233315701	[325]	[139,122,81]	-7	hSpCas9	negative selection	1854046
49296455	49296478	12	-	26627737	HCT116	viability after 8 days	TCTTGCGCTCTAGTTCCAGGCGG	PRPH	ENSG00000135406	-1.030453645554707	[246]	[61,86,50]	-8	hSpCas9	negative selection	1854047
49296990	49297013	12	-	26627737	HCT116	viability after 8 days	CGATGCTCTCGTACTGCGCGCGG	PRPH	ENSG00000135406	0.5599947373878789	[125]	[82,143,79]	5	hSpCas9	negative selection	1854048
49297234	49297257	12	+	26627737	HCT116	viability after 8 days	CCAGAGTCTAACGTGCGAGGTGG	PRPH	ENSG00000135406	0.6728398162723105	[427]	[360,335,429]	6	hSpCas9	negative selection	1854049
49297368	49297391	12	+	26627737	HCT116	viability after 8 days	GCTCAGGCAGTTGAGAGAGCTGG	PRPH	ENSG00000135406	-0.027364417551340114	[357]	[89,308,179]	0	hSpCas9	negative selection	1854050
49295475	49295498	12	-	26627737	HCT116	viability after 9 days	CTGCTTCTCGTTGCTGCGCGTGG	PRPH	ENSG00000135406	0.49122692111143634	[546]	[354,86]	3	hSpCas9	negative selection	1936360
49296217	49296240	12	+	26627737	HCT116	viability after 9 days	CAACCTCGTGCTCTTCCGCAAGG	PRPH	ENSG00000135406	2.17269263866314	[371]	[372,506]	9	hSpCas9	negative selection	1936361
49296455	49296478	12	-	26627737	HCT116	viability after 9 days	TCTTGCGCTCTAGTTCCAGGCGG	PRPH	ENSG00000135406	0.2429396448325169	[373]	[187,62]	1	hSpCas9	negative selection	1936362
49296990	49297013	12	-	26627737	HCT116	viability after 9 days	CGATGCTCTCGTACTGCGCGCGG	PRPH	ENSG00000135406	-0.2587028517825937	[436]	[163,44]	-2	hSpCas9	negative selection	1936363
49297234	49297257	12	+	26627737	HCT116	viability after 9 days	CCAGAGTCTAACGTGCGAGGTGG	PRPH	ENSG00000135406	-0.18031926062948744	[1499]	[472,258]	-1	hSpCas9	negative selection	1936364
49297368	49297391	12	+	26627737	HCT116	viability after 9 days	GCTCAGGCAGTTGAGAGAGCTGG	PRPH	ENSG00000135406	-0.458341870254361	[833]	[270,75]	-3	hSpCas9	negative selection	1936365
49295475	49295498	12	-	26627737	HCT116	viability after 12 days	CTGCTTCTCGTTGCTGCGCGTGG	PRPH	ENSG00000135406	1.1776273292645234	[203]	[210,312,207]	8	hSpCas9	negative selection	2018675
49296217	49296240	12	+	26627737	HCT116	viability after 12 days	CAACCTCGTGCTCTTCCGCAAGG	PRPH	ENSG00000135406	0.06713800524418848	[325]	[103,134,304]	0	hSpCas9	negative selection	2018676
49296455	49296478	12	-	26627737	HCT116	viability after 12 days	TCTTGCGCTCTAGTTCCAGGCGG	PRPH	ENSG00000135406	-0.9748415102079192	[246]	[86,53,54]	-8	hSpCas9	negative selection	2018677
49296990	49297013	12	-	26627737	HCT116	viability after 12 days	CGATGCTCTCGTACTGCGCGCGG	PRPH	ENSG00000135406	0.8110142360922025	[125]	[134,162,49]	7	hSpCas9	negative selection	2018678
49297234	49297257	12	+	26627737	HCT116	viability after 12 days	CCAGAGTCTAACGTGCGAGGTGG	PRPH	ENSG00000135406	0.5557842873390381	[427]	[345,307,335]	5	hSpCas9	negative selection	2018679
49297368	49297391	12	+	26627737	HCT116	viability after 12 days	GCTCAGGCAGTTGAGAGAGCTGG	PRPH	ENSG00000135406	-0.36779099579827695	[357]	[63,203,177]	-4	hSpCas9	negative selection	2018680
49295475	49295498	12	-	26627737	HCT116	viability after 15 days	CTGCTTCTCGTTGCTGCGCGTGG	PRPH	ENSG00000135406	1.560240757112068	[203]	[287,354,385]	9	hSpCas9	negative selection	2100990
49296217	49296240	12	+	26627737	HCT116	viability after 15 days	CAACCTCGTGCTCTTCCGCAAGG	PRPH	ENSG00000135406	-0.16989348899973242	[325]	[113,138,238]	-2	hSpCas9	negative selection	2100991
49296455	49296478	12	-	26627737	HCT116	viability after 15 days	TCTTGCGCTCTAGTTCCAGGCGG	PRPH	ENSG00000135406	-0.4453841174347184	[246]	[63,169,73]	-4	hSpCas9	negative selection	2100992
49296990	49297013	12	-	26627737	HCT116	viability after 15 days	CGATGCTCTCGTACTGCGCGCGG	PRPH	ENSG00000135406	0.9289010670049115	[125]	[81,144,178]	7	hSpCas9	negative selection	2100993
49297234	49297257	12	+	26627737	HCT116	viability after 15 days	CCAGAGTCTAACGTGCGAGGTGG	PRPH	ENSG00000135406	0.9053270689015239	[427]	[376,535,457]	7	hSpCas9	negative selection	2100994
49297368	49297391	12	+	26627737	HCT116	viability after 15 days	GCTCAGGCAGTTGAGAGAGCTGG	PRPH	ENSG00000135406	0.2193369977802474	[357]	[212,273,227]	2	hSpCas9	negative selection	2100995
49295475	49295498	12	-	26627737	HCT116	viability after 18 days	CTGCTTCTCGTTGCTGCGCGTGG	PRPH	ENSG00000135406	1.2184381998265728	[203]	[200,270,212]	8	hSpCas9	negative selection	2183305
49296217	49296240	12	+	26627737	HCT116	viability after 18 days	CAACCTCGTGCTCTTCCGCAAGG	PRPH	ENSG00000135406	-0.322186613385011	[325]	[123,59,201]	-3	hSpCas9	negative selection	2183306
49296455	49296478	12	-	26627737	HCT116	viability after 18 days	TCTTGCGCTCTAGTTCCAGGCGG	PRPH	ENSG00000135406	0.004627235854784251	[246]	[50,236,60]	0	hSpCas9	negative selection	2183307
49296990	49297013	12	-	26627737	HCT116	viability after 18 days	CGATGCTCTCGTACTGCGCGCGG	PRPH	ENSG00000135406	0.38560656635891766	[125]	[63,117,52]	3	hSpCas9	negative selection	2183308
49297234	49297257	12	+	26627737	HCT116	viability after 18 days	CCAGAGTCTAACGTGCGAGGTGG	PRPH	ENSG00000135406	0.9176233906140389	[427]	[212,391,575]	7	hSpCas9	negative selection	2183309
49297368	49297391	12	+	26627737	HCT116	viability after 18 days	GCTCAGGCAGTTGAGAGAGCTGG	PRPH	ENSG00000135406	-0.15848687914188986	[357]	[72,181,210]	-1	hSpCas9	negative selection	2183310
49295017	49295040	12	-	25494202	A375	resistance to PLX-4720 (puromycin)	AGGGGGATGCCCCACCCCTGCGG	PRPH	ENSG00000135406	2.3493510846998698	[41,20]	[23,46]	7	dCas9-VP64	positive selection	2439755
49294966	49294989	12	+	25494202	A375	resistance to PLX-4720 (puromycin)	GTGGGTAGAGGCCTGCAACCAGG	PRPH	ENSG00000135406	1.110708765862852	[13,65]	[20,16]	4	dCas9-VP64	positive selection	2439756
49294942	49294965	12	-	25494202	A375	resistance to PLX-4720 (puromycin)	TGATTGCCCCCTGTTGCCGCTGG	PRPH	ENSG00000135406	2.5994412041066415	[161,131]	[91,308]	8	dCas9-VP64	positive selection	2439757
49295017	49295040	12	-	25494202	A375	resistance to PLX-4720 (zeocin)	AGGGGGATGCCCCACCCCTGCGG	PRPH	ENSG00000135406	-0.8770284917163691	[173,73]	[30,12]	-7	dCas9-VP64	positive selection	2535010
49294966	49294989	12	+	25494202	A375	resistance to PLX-4720 (zeocin)	GTGGGTAGAGGCCTGCAACCAGG	PRPH	ENSG00000135406	-0.3005429220660589	[74,51]	[16,15]	-3	dCas9-VP64	positive selection	2535011
49294942	49294965	12	-	25494202	A375	resistance to PLX-4720 (zeocin)	TGATTGCCCCCTGTTGCCGCTGG	PRPH	ENSG00000135406	-0.8885070871349534	[249,245]	[42,42]	-8	dCas9-VP64	positive selection	2535012
49295270	49295293	12	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	ACCGCCCTCACTATCCCCCGGGG	PRPH	ENSG00000135406	-0.5079596587442485	[2,3]	[0,2]	-6	hSpCas9	positive selection	3013913
49295549	49295572	12	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CTTTCTGGAGCAGCAGAACGCGG	PRPH	ENSG00000135406	0.11998451469311316	[2,2]	[2,2]	2	hSpCas9	positive selection	3013914
49296504	49296527	12	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GTTCCTCAAGAAGCTGCACGAGG	PRPH	ENSG00000135406	-0.30365585970998327	[3,2]	[2,1]	-4	hSpCas9	positive selection	3013915
49296455	49296478	12	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TCTTGCGCTCTAGTTCCAGGCGG	PRPH	ENSG00000135406	-0.6888581117847462	[4,4]	[3,0]	-8	hSpCas9	positive selection	3013916
49295270	49295293	12	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	ACCGCCCTCACTATCCCCCGGGG	PRPH	ENSG00000135406	-0.048854698775688044	[2,2]	[2,1]	0	hSpCas9	positive selection	3081771
49295549	49295572	12	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CTTTCTGGAGCAGCAGAACGCGG	PRPH	ENSG00000135406	0.10842052143946376	[2,2]	[1,2]	2	hSpCas9	positive selection	3081772
49296504	49296527	12	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GTTCCTCAAGAAGCTGCACGAGG	PRPH	ENSG00000135406	0.39078618925183944	[3,3]	[3,2]	6	hSpCas9	positive selection	3081773
49296455	49296478	12	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TCTTGCGCTCTAGTTCCAGGCGG	PRPH	ENSG00000135406	-0.0466507531070022	[4,4]	[3,2]	0	hSpCas9	positive selection	3081774
49296458	49296481		-	24336571	A375	resistance to PLX after 7 days	CAATCTTGCGCTCTAGTTCCAGG	PRPH	ENSG00000135406	-0.13884246368536746	[23,19]	[18,20]	-4	hSpCas9	positive selection	3138024
49296990	49297013		-	24336571	A375	resistance to PLX after 7 days	CGATGCTCTCGTACTGCGCGCGG	PRPH	ENSG00000135406	0.18892440512415998	[16,15]	[16,20]	6	hSpCas9	positive selection	3138025
49296470	49296493		+	24336571	A375	resistance to PLX after 7 days	GCGCAAGATTGAGTCTCTGATGG	PRPH	ENSG00000135406	0.10064181140170136	[6,7]	[6,7]	3	hSpCas9	positive selection	3138026
49296458	49296481		-	24336571	A375	resistance to PLX after 14 days	CAATCTTGCGCTCTAGTTCCAGG	PRPH	ENSG00000135406	-0.49121002808467706	[10,29]	[6,4]	-6	hSpCas9	positive selection	3195817
49296990	49297013		-	24336571	A375	resistance to PLX after 14 days	CGATGCTCTCGTACTGCGCGCGG	PRPH	ENSG00000135406	0.611579940069191	[13,15]	[11,8]	5	hSpCas9	positive selection	3195818
49296470	49296493		+	24336571	A375	resistance to PLX after 14 days	GCGCAAGATTGAGTCTCTGATGG	PRPH	ENSG00000135406	-0.45671430218479236	[6,13]	[2,3]	-5	hSpCas9	positive selection	3195819
49296458	49296481		-	24336571	A375	viability after 7 days	CAATCTTGCGCTCTAGTTCCAGG	PRPH	ENSG00000135406	0.996709880310955	[10]	[23,19]	9	hSpCas9	negative selection	3253610
49296990	49297013		-	24336571	A375	viability after 7 days	CGATGCTCTCGTACTGCGCGCGG	PRPH	ENSG00000135406	0.2743059942021826	[13]	[16,15]	4	hSpCas9	negative selection	3253611
49296470	49296493		+	24336571	A375	viability after 7 days	GCGCAAGATTGAGTCTCTGATGG	PRPH	ENSG00000135406	-0.532405589160175	[10]	[6,7]	-6	hSpCas9	negative selection	3253612
49296458	49296481		-	24336571	A375	viability after 14 days	CAATCTTGCGCTCTAGTTCCAGG	PRPH	ENSG00000135406	0.878625740655268	[10]	[10,29]	9	hSpCas9	negative selection	3311403
49296990	49297013		-	24336571	A375	viability after 14 days	CGATGCTCTCGTACTGCGCGCGG	PRPH	ENSG00000135406	0.16136435946371208	[13]	[13,15]	2	hSpCas9	negative selection	3311404
49296470	49296493		+	24336571	A375	viability after 14 days	GCGCAAGATTGAGTCTCTGATGG	PRPH	ENSG00000135406	-0.0472057791291125	[10]	[6,13]	0	hSpCas9	negative selection	3311405
49296458	49296481	12	-	27383988	293T	resistance to West Nile virus (flavivirus)	CAATCTTGCGCTCTAGTTCCAGG	PRPH	ENSG00000135406	-0.4080097057393411	[202,202]	[0,0]	-3	hSpCas9	positive selection	3387676
49297155	49297178	12	+	27383988	293T	resistance to West Nile virus (flavivirus)	ACCTGTCCGACGCTGCCAACCGG	PRPH	ENSG00000135406	-0.7650416015826192	[259,259]	[0,0]	-5	hSpCas9	positive selection	3387677
49296470	49296493	12	+	27383988	293T	resistance to West Nile virus (flavivirus)	GCGCAAGATTGAGTCTCTGATGG	PRPH	ENSG00000135406	0.8479352753081334	[84,84]	[0,0]	4	hSpCas9	positive selection	3387678
49295269	49295292	12	+	26780180	HT29	viability (Avana library 4 designs)	ACCGCCCTCACTATCCCCCGGGG	PRPH	ENSG00000135406	1.09131429928214	[]	[]	4	hSpCas9	negative selection	3452108
49295548	49295571	12	+	26780180	HT29	viability (Avana library 4 designs)	CTTTCTGGAGCAGCAGAACGCGG	PRPH	ENSG00000135406	2.39143144089008	[]	[]	8	hSpCas9	negative selection	3452109
49296503	49296526	12	+	26780180	HT29	viability (Avana library 4 designs)	GTTCCTCAAGAAGCTGCACGAGG	PRPH	ENSG00000135406	0.13127610259833	[]	[]	0	hSpCas9	negative selection	3452110
49296455	49296478	12	-	26780180	HT29	viability (Avana library 4 designs)	TCTTGCGCTCTAGTTCCAGGCGG	PRPH	ENSG00000135406	0.370561225568787	[]	[]	1	hSpCas9	negative selection	3452111
49296455	49296478	12	-	26780180	A375	viability (Avana lentiCRISPRv2)	TCTTGCGCTCTAGTTCCAGGCGG	PRPH	ENSG00000135406	-1.43371929430021	[]	[]	-2	hSpCas9	negative selection	3548322
49295269	49295292	12	+	26780180	A375	viability (Avana lentiCRISPRv2)	ACCGCCCTCACTATCCCCCGGGG	PRPH	ENSG00000135406	2.27273560294931	[]	[]	3	hSpCas9	negative selection	3548323
49296503	49296526	12	+	26780180	A375	viability (Avana lentiCRISPRv2)	GTTCCTCAAGAAGCTGCACGAGG	PRPH	ENSG00000135406	-2.89323747854597	[]	[]	-3	hSpCas9	negative selection	3548324
49295548	49295571	12	+	26780180	A375	viability (Avana lentiCRISPRv2)	CTTTCTGGAGCAGCAGAACGCGG	PRPH	ENSG00000135406	4.09274059572096	[]	[]	6	hSpCas9	negative selection	3548325
49295421	49295444	12	-	26780180	A375	viability (Avana lentiCRISPRv2)	GGAGAAGTCGAGGCGCTCCGAGG	PRPH	ENSG00000135406	1.36041879589858	[]	[]	2	hSpCas9	negative selection	3548326
49295425	49295448	12	+	26780180	A375	viability (Avana lentiCRISPRv2)	GGAGCGCCTCGACTTCTCCATGG	PRPH	ENSG00000135406	1.25479894443781	[]	[]	1	hSpCas9	negative selection	3548327
49296455	49296478	12	-	26780180	A375	viability (Avana lentiGuide)	TCTTGCGCTCTAGTTCCAGGCGG	PRPH	ENSG00000135406	0.0279587445741781	[]	[]	0	hSpCas9	negative selection	3656981
49295269	49295292	12	+	26780180	A375	viability (Avana lentiGuide)	ACCGCCCTCACTATCCCCCGGGG	PRPH	ENSG00000135406	1.06764873993838	[]	[]	1	hSpCas9	negative selection	3656982
49296503	49296526	12	+	26780180	A375	viability (Avana lentiGuide)	GTTCCTCAAGAAGCTGCACGAGG	PRPH	ENSG00000135406	5.86473042359457	[]	[]	5	hSpCas9	negative selection	3656983
49295548	49295571	12	+	26780180	A375	viability (Avana lentiGuide)	CTTTCTGGAGCAGCAGAACGCGG	PRPH	ENSG00000135406	15.1219913323925	[]	[]	8	hSpCas9	negative selection	3656984
49295421	49295444	12	-	26780180	A375	viability (Avana lentiGuide)	GGAGAAGTCGAGGCGCTCCGAGG	PRPH	ENSG00000135406	3.10845368759018	[]	[]	3	hSpCas9	negative selection	3656985
49295425	49295448	12	+	26780180	A375	viability (Avana lentiGuide)	GGAGCGCCTCGACTTCTCCATGG	PRPH	ENSG00000135406	13.9820201833977	[]	[]	7	hSpCas9	negative selection	3656986
49296455	49296478	12	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TCTTGCGCTCTAGTTCCAGGCGG	PRPH	ENSG00000135406	-0.44262488410549505	[4]	[3,2]	-6	hSpCas9	positive selection	3765588
49295269	49295292	12	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ACCGCCCTCACTATCCCCCGGGG	PRPH	ENSG00000135406	0.11511060438637187	[4]	[5,3]	3	hSpCas9	positive selection	3765589
49296503	49296526	12	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GTTCCTCAAGAAGCTGCACGAGG	PRPH	ENSG00000135406	-0.0980028167179278	[4]	[5,2]	-2	hSpCas9	positive selection	3765590
49295548	49295571	12	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CTTTCTGGAGCAGCAGAACGCGG	PRPH	ENSG00000135406	0.3978044316587618	[4]	[5,6]	9	hSpCas9	positive selection	3765591
49295421	49295444	12	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGAGAAGTCGAGGCGCTCCGAGG	PRPH	ENSG00000135406	0.14583054145284974	[4]	[5,4]	4	hSpCas9	positive selection	3765592
49295425	49295448	12	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGAGCGCCTCGACTTCTCCATGG	PRPH	ENSG00000135406	-0.47600186166387515	[4]	[3,2]	-6	hSpCas9	positive selection	3765593
49296455	49296478	12	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TCTTGCGCTCTAGTTCCAGGCGG	PRPH	ENSG00000135406	-0.17500522232592045	[6]	[4,4]	-2	hSpCas9	positive selection	3874195
49295269	49295292	12	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ACCGCCCTCACTATCCCCCGGGG	PRPH	ENSG00000135406	-0.9524890289680228	[4]	[2,0]	-8	hSpCas9	positive selection	3874196
49296503	49296526	12	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GTTCCTCAAGAAGCTGCACGAGG	PRPH	ENSG00000135406	-0.526827652302555	[5]	[0,4]	-6	hSpCas9	positive selection	3874197
49295548	49295571	12	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CTTTCTGGAGCAGCAGAACGCGG	PRPH	ENSG00000135406	-0.056631578788760545	[4]	[4,3]	-1	hSpCas9	positive selection	3874198
49295421	49295444	12	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGAGAAGTCGAGGCGCTCCGAGG	PRPH	ENSG00000135406	0.15762050702193584	[4]	[4,3]	3	hSpCas9	positive selection	3874199
49295425	49295448	12	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGAGCGCCTCGACTTCTCCATGG	PRPH	ENSG00000135406	0.1320641236137616	[5]	[3,5]	3	hSpCas9	positive selection	3874200
49297155	49297178	12	+	26780180	A375	viability	ACCTGTCCGACGCTGCCAACCGG	PRPH	ENSG00000135406	0.161818250722004	[]	[]	0	hSpCas9	negative selection	3984651
49296458	49296481	12	-	26780180	A375	viability	CAATCTTGCGCTCTAGTTCCAGG	PRPH	ENSG00000135406	0.471421073469878	[]	[]	1	hSpCas9	negative selection	3984652
49297008	49297031	12	+	26780180	A375	viability	CATCGCCGCGAAGAACCTGCAGG	PRPH	ENSG00000135406	1.2896699737967	[]	[]	7	hSpCas9	negative selection	3984653
49297234	49297257	12	-	26780180	A375	viability	CCACCTCGCACGTTAGACTCTGG	PRPH	ENSG00000135406	1.83247953561754	[]	[]	9	hSpCas9	negative selection	3984654
49296990	49297013	12	-	26780180	A375	viability	CGATGCTCTCGTACTGCGCGCGG	PRPH	ENSG00000135406	0.886690489031845	[]	[]	4	hSpCas9	negative selection	3984655
49296470	49296493	12	+	26780180	A375	viability	GCGCAAGATTGAGTCTCTGATGG	PRPH	ENSG00000135406	1.61942176618603	[]	[]	8	hSpCas9	negative selection	3984656
49297155	49297178	12	+	26780180	HT29	viability (GeCKOv2 library)	ACCTGTCCGACGCTGCCAACCGG	PRPH	ENSG00000135406	0.802764213240263	[]	[]	3	hSpCas9	negative selection	4092617
49296458	49296481	12	-	26780180	HT29	viability (GeCKOv2 library)	CAATCTTGCGCTCTAGTTCCAGG	PRPH	ENSG00000135406	0.869699769697581	[]	[]	3	hSpCas9	negative selection	4092618
49297008	49297031	12	+	26780180	HT29	viability (GeCKOv2 library)	CATCGCCGCGAAGAACCTGCAGG	PRPH	ENSG00000135406	1.84009451679227	[]	[]	8	hSpCas9	negative selection	4092619
49297234	49297257	12	-	26780180	HT29	viability (GeCKOv2 library)	CCACCTCGCACGTTAGACTCTGG	PRPH	ENSG00000135406	1.65536623187075	[]	[]	8	hSpCas9	negative selection	4092620
49296990	49297013	12	-	26780180	HT29	viability (GeCKOv2 library)	CGATGCTCTCGTACTGCGCGCGG	PRPH	ENSG00000135406	1.15988865207221	[]	[]	5	hSpCas9	negative selection	4092621
49296470	49296493	12	+	26780180	HT29	viability (GeCKOv2 library)	GCGCAAGATTGAGTCTCTGATGG	PRPH	ENSG00000135406	1.41444450590299	[]	[]	7	hSpCas9	negative selection	4092622
49296458	49296481	12	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CAATCTTGCGCTCTAGTTCCAGG	PRPH	ENSG00000135406	0.24209145087447473	[3]	[3,2]	6	hSpCas9	positive selection	4163202
49296990	49297013	12	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CGATGCTCTCGTACTGCGCGCGG	PRPH	ENSG00000135406	0.062222014987874774	[4]	[2,3]	1	hSpCas9	positive selection	4163203
49296470	49296493	12	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GCGCAAGATTGAGTCTCTGATGG	PRPH	ENSG00000135406	-0.11552367864211016	[2]	[1,1]	-3	hSpCas9	positive selection	4163204
49296458	49296481	12	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CAATCTTGCGCTCTAGTTCCAGG	PRPH	ENSG00000135406	0.33096397949332057	[1]	[1,0,0,0]	2	hSpCas9	positive selection	4227224
49296990	49297013	12	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CGATGCTCTCGTACTGCGCGCGG	PRPH	ENSG00000135406	0.7629563938589321	[3]	[6,3,2,0]	5	hSpCas9	positive selection	4227225
49296470	49296493	12	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GCGCAAGATTGAGTCTCTGATGG	PRPH	ENSG00000135406	-0.3582695284199072	[3]	[0,3,0,0]	-5	hSpCas9	positive selection	4227226
49296990	49297013	12	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CGATGCTCTCGTACTGCGCGCGG	PRPH	ENSG00000135406	0.33485054650967555	[2]	[3,2]	6	hSpCas9	positive selection	4292383
49297234	49297257	12	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCACCTCGCACGTTAGACTCTGG	PRPH	ENSG00000135406	-0.12243700761299453	[3]	[2,2]	-2	hSpCas9	positive selection	4292384
49297008	49297031	12	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CATCGCCGCGAAGAACCTGCAGG	PRPH	ENSG00000135406	-0.322957237968115	[2]	[3,0]	-6	hSpCas9	positive selection	4292385
49296458	49296481	12	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CAATCTTGCGCTCTAGTTCCAGG	PRPH	ENSG00000135406	0.4012766783968661	[3]	[4,3]	7	hSpCas9	positive selection	4356642
49297155	49297178	12	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ACCTGTCCGACGCTGCCAACCGG	PRPH	ENSG00000135406	0.4521580361560886	[3]	[4,3]	8	hSpCas9	positive selection	4356643
49296470	49296493	12	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GCGCAAGATTGAGTCTCTGATGG	PRPH	ENSG00000135406	-0.42377630169049363	[2]	[2,0]	-7	hSpCas9	positive selection	4356644
49295375	49295397	12	+	27760321	OCIAML3	viability	AGCTTCCGTAGCCCCCGAGCGG	PRPH	ENSG00000135406	-0.04205691350715668	[884,807]	[551,760]	0	hSpCas9	negative selection	4430906
49296218	49296240	12	+	27760321	OCIAML3	viability	AACCTCGTGCTCTTCCGCAAGG	PRPH	ENSG00000135406	0.22001365533369865	[926,820]	[753,847]	2	hSpCas9	negative selection	4430907
49296454	49296476	12	-	27760321	OCIAML3	viability	TTGCGCTCTAGTTCCAGGCGGG	PRPH	ENSG00000135406	-0.8887638727876648	[850,750]	[180,541]	-7	hSpCas9	negative selection	4430908
49296961	49296983	12	-	27760321	OCIAML3	viability	TCAGCGCTGCCGTCAGCTCGGG	PRPH	ENSG00000135406	0.6428481886110646	[715,519]	[597,941]	7	hSpCas9	negative selection	4430909
49297240	49297262	12	+	27760321	OCIAML3	viability	TCTAACGTGCGAGGTGGACGGG	PRPH	ENSG00000135406	-0.6747470281998251	[432,392]	[219,178]	-6	hSpCas9	negative selection	4430910
49295375	49295397	12	+	27760321	OCIAML2	viability	AGCTTCCGTAGCCCCCGAGCGG	PRPH	ENSG00000135406	0.5697626520302674	[884,807]	[813,1281]	7	hSpCas9	negative selection	4514369
49296218	49296240	12	+	27760321	OCIAML2	viability	AACCTCGTGCTCTTCCGCAAGG	PRPH	ENSG00000135406	0.31974112439391345	[926,820]	[886,872]	4	hSpCas9	negative selection	4514370
49296454	49296476	12	-	27760321	OCIAML2	viability	TTGCGCTCTAGTTCCAGGCGGG	PRPH	ENSG00000135406	-0.9484148891349652	[850,750]	[206,503]	-7	hSpCas9	negative selection	4514371
49296961	49296983	12	-	27760321	OCIAML2	viability	TCAGCGCTGCCGTCAGCTCGGG	PRPH	ENSG00000135406	0.05121212568986894	[715,519]	[455,587]	0	hSpCas9	negative selection	4514372
49297240	49297262	12	+	27760321	OCIAML2	viability	TCTAACGTGCGAGGTGGACGGG	PRPH	ENSG00000135406	-0.2056746591679899	[432,392]	[235,359]	-3	hSpCas9	negative selection	4514373
49295375	49295397	12	+	27760321	MV411	viability	AGCTTCCGTAGCCCCCGAGCGG	PRPH	ENSG00000135406	0.08135967226627283	[884,807]	[527,684]	0	hSpCas9	negative selection	4597832
49296218	49296240	12	+	27760321	MV411	viability	AACCTCGTGCTCTTCCGCAAGG	PRPH	ENSG00000135406	0.02395787445466535	[926,820]	[606,552]	0	hSpCas9	negative selection	4597833
49296454	49296476	12	-	27760321	MV411	viability	TTGCGCTCTAGTTCCAGGCGGG	PRPH	ENSG00000135406	-1.5861223515624574	[850,750]	[88,305]	-7	hSpCas9	negative selection	4597834
49296961	49296983	12	-	27760321	MV411	viability	TCAGCGCTGCCGTCAGCTCGGG	PRPH	ENSG00000135406	0.1935519751614207	[715,519]	[500,402]	1	hSpCas9	negative selection	4597835
49297240	49297262	12	+	27760321	MV411	viability	TCTAACGTGCGAGGTGGACGGG	PRPH	ENSG00000135406	-2.1638893014807135	[432,392]	[31,103]	-8	hSpCas9	negative selection	4597836
49295375	49295397	12	+	27760321	HL60	viability	AGCTTCCGTAGCCCCCGAGCGG	PRPH	ENSG00000135406	0.3123957919030034	[884,807]	[850,865]	4	hSpCas9	negative selection	4681295
49296218	49296240	12	+	27760321	HL60	viability	AACCTCGTGCTCTTCCGCAAGG	PRPH	ENSG00000135406	0.7792595698965723	[926,820]	[1164,1284]	8	hSpCas9	negative selection	4681296
49296454	49296476	12	-	27760321	HL60	viability	TTGCGCTCTAGTTCCAGGCGGG	PRPH	ENSG00000135406	-0.42427055434003585	[850,750]	[443,531]	-5	hSpCas9	negative selection	4681297
49296961	49296983	12	-	27760321	HL60	viability	TCAGCGCTGCCGTCAGCTCGGG	PRPH	ENSG00000135406	-0.45562832759437266	[715,519]	[315,415]	-5	hSpCas9	negative selection	4681298
49297240	49297262	12	+	27760321	HL60	viability	TCTAACGTGCGAGGTGGACGGG	PRPH	ENSG00000135406	0.4486915553656404	[432,392]	[397,525]	5	hSpCas9	negative selection	4681299
49295375	49295397	12	+	27760321	HT1080	viability	AGCTTCCGTAGCCCCCGAGCGG	PRPH	ENSG00000135406	-0.7820353899581445	[807,630]	[96,242]	-3	hSpCas9	negative selection	4764758
49296218	49296240	12	+	27760321	HT1080	viability	AACCTCGTGCTCTTCCGCAAGG	PRPH	ENSG00000135406	0.5224250479438943	[820,640]	[434,399]	2	hSpCas9	negative selection	4764759
49296454	49296476	12	-	27760321	HT1080	viability	TTGCGCTCTAGTTCCAGGCGGG	PRPH	ENSG00000135406	-0.9945766119714594	[750,585]	[157,106]	-4	hSpCas9	negative selection	4764760
49296961	49296983	12	-	27760321	HT1080	viability	TCAGCGCTGCCGTCAGCTCGGG	PRPH	ENSG00000135406	0.20452839744128448	[519,405]	[223,199]	1	hSpCas9	negative selection	4764761
49297240	49297262	12	+	27760321	HT1080	viability	TCTAACGTGCGAGGTGGACGGG	PRPH	ENSG00000135406	-0.34834358694782414	[392,306]	[88,131]	-2	hSpCas9	negative selection	4764762
49295375	49295397	12	+	27760321	HT29	viability after 7 days	AGCTTCCGTAGCCCCCGAGCGG	PRPH	ENSG00000135406	0.1849582079314409	[807,630]	[1052,1156,946]	3	hSpCas9	negative selection	4848221
49296218	49296240	12	+	27760321	HT29	viability after 7 days	AACCTCGTGCTCTTCCGCAAGG	PRPH	ENSG00000135406	0.2955283145848928	[820,640]	[874,1382,1160]	4	hSpCas9	negative selection	4848222
49296454	49296476	12	-	27760321	HT29	viability after 7 days	TTGCGCTCTAGTTCCAGGCGGG	PRPH	ENSG00000135406	-1.2952666832916702	[750,585]	[448,353,263]	-9	hSpCas9	negative selection	4848223
49296961	49296983	12	-	27760321	HT29	viability after 7 days	TCAGCGCTGCCGTCAGCTCGGG	PRPH	ENSG00000135406	0.3637128323376204	[519,405]	[531,1044,688]	5	hSpCas9	negative selection	4848224
49297240	49297262	12	+	27760321	HT29	viability after 7 days	TCTAACGTGCGAGGTGGACGGG	PRPH	ENSG00000135406	0.008121613834969486	[392,306]	[467,589,305]	0	hSpCas9	negative selection	4848225
49295375	49295397	12	+	27760321	HT29	viability after 25 days	AGCTTCCGTAGCCCCCGAGCGG	PRPH	ENSG00000135406	0.30604803345786236	[807,630]	[1007,1065,969]	3	hSpCas9	negative selection	4931684
49296218	49296240	12	+	27760321	HT29	viability after 25 days	AACCTCGTGCTCTTCCGCAAGG	PRPH	ENSG00000135406	0.5609874452030785	[820,640]	[995,1623,1073]	6	hSpCas9	negative selection	4931685
49296454	49296476	12	-	27760321	HT29	viability after 25 days	TTGCGCTCTAGTTCCAGGCGGG	PRPH	ENSG00000135406	-0.747294228118712	[750,585]	[597,376,371]	-6	hSpCas9	negative selection	4931686
49296961	49296983	12	-	27760321	HT29	viability after 25 days	TCAGCGCTGCCGTCAGCTCGGG	PRPH	ENSG00000135406	0.4057919087172952	[519,405]	[642,723,742]	4	hSpCas9	negative selection	4931687
49297240	49297262	12	+	27760321	HT29	viability after 25 days	TCTAACGTGCGAGGTGGACGGG	PRPH	ENSG00000135406	0.06625040137496993	[392,306]	[295,423,557]	0	hSpCas9	negative selection	4931688
49295375	49295397	12	+	27760321	HT29	viability after 22 days	AGCTTCCGTAGCCCCCGAGCGG	PRPH	ENSG00000135406	0.35543204738881107	[807,630]	[911,973,1312]	4	hSpCas9	negative selection	5015147
49296218	49296240	12	+	27760321	HT29	viability after 22 days	AACCTCGTGCTCTTCCGCAAGG	PRPH	ENSG00000135406	0.5604420062687914	[820,640]	[1036,1296,1411]	6	hSpCas9	negative selection	5015148
49296454	49296476	12	-	27760321	HT29	viability after 22 days	TTGCGCTCTAGTTCCAGGCGGG	PRPH	ENSG00000135406	-0.31317720346964817	[750,585]	[890,630,333]	-3	hSpCas9	negative selection	5015149
49296961	49296983	12	-	27760321	HT29	viability after 22 days	TCAGCGCTGCCGTCAGCTCGGG	PRPH	ENSG00000135406	0.369731586466419	[519,405]	[641,969,461]	4	hSpCas9	negative selection	5015150
49297240	49297262	12	+	27760321	HT29	viability after 22 days	TCTAACGTGCGAGGTGGACGGG	PRPH	ENSG00000135406	-0.32790448979926146	[392,306]	[189,320,460]	-3	hSpCas9	negative selection	5015151
49295375	49295397	12	+	27760321	HT29	viability after 19 days	AGCTTCCGTAGCCCCCGAGCGG	PRPH	ENSG00000135406	0.7142414589514483	[807,630]	[1229,1811,1007]	7	hSpCas9	negative selection	5098610
49296218	49296240	12	+	27760321	HT29	viability after 19 days	AACCTCGTGCTCTTCCGCAAGG	PRPH	ENSG00000135406	0.21517826832999387	[820,640]	[1113,896,916]	2	hSpCas9	negative selection	5098611
49296454	49296476	12	-	27760321	HT29	viability after 19 days	TTGCGCTCTAGTTCCAGGCGGG	PRPH	ENSG00000135406	-0.318154300367505	[750,585]	[807,500,552]	-3	hSpCas9	negative selection	5098612
49296961	49296983	12	-	27760321	HT29	viability after 19 days	TCAGCGCTGCCGTCAGCTCGGG	PRPH	ENSG00000135406	0.7396582787378416	[519,405]	[834,823,983]	7	hSpCas9	negative selection	5098613
49297240	49297262	12	+	27760321	HT29	viability after 19 days	TCTAACGTGCGAGGTGGACGGG	PRPH	ENSG00000135406	0.4663166445779248	[392,306]	[279,576,764]	4	hSpCas9	negative selection	5098614
49295375	49295397	12	+	27760321	HT29	viability after 16 days	AGCTTCCGTAGCCCCCGAGCGG	PRPH	ENSG00000135406	0.7576979143457485	[807,630]	[1271,1386,1414]	8	hSpCas9	negative selection	5182073
49296218	49296240	12	+	27760321	HT29	viability after 16 days	AACCTCGTGCTCTTCCGCAAGG	PRPH	ENSG00000135406	0.14618760081831317	[820,640]	[1025,886,813]	1	hSpCas9	negative selection	5182074
49296454	49296476	12	-	27760321	HT29	viability after 16 days	TTGCGCTCTAGTTCCAGGCGGG	PRPH	ENSG00000135406	-0.7805430056458549	[750,585]	[559,430,326]	-6	hSpCas9	negative selection	5182075
49296961	49296983	12	-	27760321	HT29	viability after 16 days	TCAGCGCTGCCGTCAGCTCGGG	PRPH	ENSG00000135406	0.5034934568256797	[519,405]	[790,746,669]	6	hSpCas9	negative selection	5182076
49297240	49297262	12	+	27760321	HT29	viability after 16 days	TCTAACGTGCGAGGTGGACGGG	PRPH	ENSG00000135406	-0.2960981240411828	[392,306]	[270,404,273]	-3	hSpCas9	negative selection	5182077
49295375	49295397	12	+	27760321	HT29	viability after 13 days	AGCTTCCGTAGCCCCCGAGCGG	PRPH	ENSG00000135406	0.5379764738478896	[807,630]	[1696,971,979]	7	hSpCas9	negative selection	5265536
49296218	49296240	12	+	27760321	HT29	viability after 13 days	AACCTCGTGCTCTTCCGCAAGG	PRPH	ENSG00000135406	0.21358976724852408	[820,640]	[920,1060,968]	2	hSpCas9	negative selection	5265537
49296454	49296476	12	-	27760321	HT29	viability after 13 days	TTGCGCTCTAGTTCCAGGCGGG	PRPH	ENSG00000135406	-0.6986671530509927	[750,585]	[450,598,388]	-6	hSpCas9	negative selection	5265538
49296961	49296983	12	-	27760321	HT29	viability after 13 days	TCAGCGCTGCCGTCAGCTCGGG	PRPH	ENSG00000135406	0.652265391259564	[519,405]	[774,647,1093]	8	hSpCas9	negative selection	5265539
49297240	49297262	12	+	27760321	HT29	viability after 13 days	TCTAACGTGCGAGGTGGACGGG	PRPH	ENSG00000135406	0.07863205306928969	[392,306]	[348,584,356]	0	hSpCas9	negative selection	5265540
49295375	49295397	12	+	27760321	HT29	viability after 10 days	AGCTTCCGTAGCCCCCGAGCGG	PRPH	ENSG00000135406	0.056604883107982396	[807,630]	[1064,939,800]	0	hSpCas9	negative selection	5348999
49296218	49296240	12	+	27760321	HT29	viability after 10 days	AACCTCGTGCTCTTCCGCAAGG	PRPH	ENSG00000135406	0.35597303271049596	[820,640]	[1451,1136,919]	5	hSpCas9	negative selection	5349000
49296454	49296476	12	-	27760321	HT29	viability after 10 days	TTGCGCTCTAGTTCCAGGCGGG	PRPH	ENSG00000135406	-0.4491188293786567	[750,585]	[660,628,545]	-5	hSpCas9	negative selection	5349001
49296961	49296983	12	-	27760321	HT29	viability after 10 days	TCAGCGCTGCCGTCAGCTCGGG	PRPH	ENSG00000135406	0.6177472602493265	[519,405]	[859,1037,769]	8	hSpCas9	negative selection	5349002
49297240	49297262	12	+	27760321	HT29	viability after 10 days	TCTAACGTGCGAGGTGGACGGG	PRPH	ENSG00000135406	0.036121933480444075	[392,306]	[401,343,591]	0	hSpCas9	negative selection	5349003
49295375	49295397	12	+	27760321	MOLM13	viability	AGCTTCCGTAGCCCCCGAGCGG	PRPH	ENSG00000135406	0.25638453936325	[884,807]	[647,503]	1	hSpCas9	negative selection	5432462
49296218	49296240	12	+	27760321	MOLM13	viability	AACCTCGTGCTCTTCCGCAAGG	PRPH	ENSG00000135406	0.08629483917056158	[926,820]	[473,563]	0	hSpCas9	negative selection	5432463
49296454	49296476	12	-	27760321	MOLM13	viability	TTGCGCTCTAGTTCCAGGCGGG	PRPH	ENSG00000135406	-1.0657891886811748	[850,750]	[181,243]	-6	hSpCas9	negative selection	5432464
49296961	49296983	12	-	27760321	MOLM13	viability	TCAGCGCTGCCGTCAGCTCGGG	PRPH	ENSG00000135406	0.4890227174609835	[715,519]	[294,645]	3	hSpCas9	negative selection	5432465
49297240	49297262	12	+	27760321	MOLM13	viability	TCTAACGTGCGAGGTGGACGGG	PRPH	ENSG00000135406	0.6402253672444299	[432,392]	[511,235]	4	hSpCas9	negative selection	5432466
49295732	49295755	12	+	27661255	K562	viability	GCGCTCAAGCAGAGGTCAGGGGG	PRPH	ENSG00000135406	0.07557539363431981	[526,736]	[544,514]	2	dCas9-KRAB	negative selection	5504420
49295783	49295806	12	+	27661255	K562	viability	GGTCGAAGCGGCCGTCGAGGCGG	PRPH	ENSG00000135406	0.030087756894856987	[1418,1538]	[1230,1181]	1	dCas9-KRAB	negative selection	5504421
49295185	49295208	12	-	27661255	K562	viability	GGCTCATTGCGGCCAAGGATGGG	PRPH	ENSG00000135406	0.22174708106674818	[862,991]	[931,801]	7	dCas9-KRAB	negative selection	5504422
49295241	49295264	12	-	27661255	K562	viability	GAAGGTACGGCGGTATGAGGTGG	PRPH	ENSG00000135406	0.6491240751483403	[591,587]	[844,648]	9	dCas9-KRAB	negative selection	5504423
49295251	49295274	12	-	27661255	K562	viability	GCGGTGGACCGAAGGTACGGCGG	PRPH	ENSG00000135406	-0.0185022509085932	[682,700]	[572,521]	0	dCas9-KRAB	negative selection	5504424
49296990	49297013	12	-	27260156	BXPC3	viability	CGATGCTCTCGTACTGCGCGCGG	PRPH	ENSG00000135406	-0.1418951663784419	[447]	[442,435,385,426]	-3	hSpCas9	negative selection	5564843
49297234	49297257	12	-	27260156	BXPC3	viability	CCACCTCGCACGTTAGACTCTGG	PRPH	ENSG00000135406	0.038795365338090804	[884]	[874,743,950,1287]	0	hSpCas9	negative selection	5564844
49297008	49297031	12	+	27260156	BXPC3	viability	CATCGCCGCGAAGAACCTGCAGG	PRPH	ENSG00000135406	-0.12162168739798357	[376]	[324,362,354,413]	-3	hSpCas9	negative selection	5564845
49296458	49296481	12	-	27260156	BXPC3	viability	CAATCTTGCGCTCTAGTTCCAGG	PRPH	ENSG00000135406	-0.03296412114912811	[631]	[670,490,736,693]	0	hSpCas9	negative selection	5629102
49297155	49297178	12	+	27260156	BXPC3	viability	ACCTGTCCGACGCTGCCAACCGG	PRPH	ENSG00000135406	-0.13644058301080053	[822]	[651,730,781,1005]	-3	hSpCas9	negative selection	5629103
49296470	49296493	12	+	27260156	BXPC3	viability	GCGCAAGATTGAGTCTCTGATGG	PRPH	ENSG00000135406	-0.4603505056026044	[396]	[227,287,275,437]	-7	hSpCas9	negative selection	5629104
49296990	49297013	12	-	27260156	A673	viability	CGATGCTCTCGTACTGCGCGCGG	PRPH	ENSG00000135406	-0.13061254188564303	[447]	[582,426,502,461]	-3	hSpCas9	negative selection	5686094
49297234	49297257	12	-	27260156	A673	viability	CCACCTCGCACGTTAGACTCTGG	PRPH	ENSG00000135406	-0.12970889273313746	[884]	[1097,926,852,1024]	-3	hSpCas9	negative selection	5686095
49297008	49297031	12	+	27260156	A673	viability	CATCGCCGCGAAGAACCTGCAGG	PRPH	ENSG00000135406	-0.320934031039196	[376]	[347,403,307,387]	-7	hSpCas9	negative selection	5686096
49296458	49296481	12	-	27260156	A673	viability	CAATCTTGCGCTCTAGTTCCAGG	PRPH	ENSG00000135406	0.12491881369568841	[631]	[926,800,751,841]	3	hSpCas9	negative selection	5750353
49297155	49297178	12	+	27260156	A673	viability	ACCTGTCCGACGCTGCCAACCGG	PRPH	ENSG00000135406	0.22553239601919195	[822]	[1315,1010,1065,1254]	5	hSpCas9	negative selection	5750354
49296470	49296493	12	+	27260156	A673	viability	GCGCAAGATTGAGTCTCTGATGG	PRPH	ENSG00000135406	-0.004122233478105919	[396]	[425,484,494,488]	0	hSpCas9	negative selection	5750355
49296990	49297013	12	-	27260156	A375	viability	CGATGCTCTCGTACTGCGCGCGG	PRPH	ENSG00000135406	0.018760525722498624	[447]	[461,665,600,420]	0	hSpCas9	negative selection	5807345
49297234	49297257	12	-	27260156	A375	viability	CCACCTCGCACGTTAGACTCTGG	PRPH	ENSG00000135406	0.07851415395878891	[884]	[1023,1291,1054,1025]	1	hSpCas9	negative selection	5807346
49297008	49297031	12	+	27260156	A375	viability	CATCGCCGCGAAGAACCTGCAGG	PRPH	ENSG00000135406	0.23237103408408524	[376]	[385,660,538,501]	3	hSpCas9	negative selection	5807347
49296458	49296481	12	-	27260156	A375	viability	CAATCTTGCGCTCTAGTTCCAGG	PRPH	ENSG00000135406	0.40158190433698954	[631]	[914,1081,892,1015]	6	hSpCas9	negative selection	5871604
49297155	49297178	12	+	27260156	A375	viability	ACCTGTCCGACGCTGCCAACCGG	PRPH	ENSG00000135406	0.22662982247241903	[822]	[1116,1237,1165,1003]	3	hSpCas9	negative selection	5871605
49296470	49296493	12	+	27260156	A375	viability	GCGCAAGATTGAGTCTCTGATGG	PRPH	ENSG00000135406	-0.43955845237780355	[396]	[497,184,314,346]	-6	hSpCas9	negative selection	5871606
49296990	49297013	12	-	27260156	COLO741	viability	CGATGCTCTCGTACTGCGCGCGG	PRPH	ENSG00000135406	-0.025559783595563546	[447]	[557,502,619]	0	hSpCas9	negative selection	5928596
49297234	49297257	12	-	27260156	COLO741	viability	CCACCTCGCACGTTAGACTCTGG	PRPH	ENSG00000135406	-0.003714471767766736	[884]	[1150,1215,1023]	0	hSpCas9	negative selection	5928597
49297008	49297031	12	+	27260156	COLO741	viability	CATCGCCGCGAAGAACCTGCAGG	PRPH	ENSG00000135406	0.07567092476610304	[376]	[713,430,401]	1	hSpCas9	negative selection	5928598
49296458	49296481	12	-	27260156	COLO741	viability	CAATCTTGCGCTCTAGTTCCAGG	PRPH	ENSG00000135406	-0.21218253337049287	[631]	[827,554,715]	-4	hSpCas9	negative selection	5992855
49297155	49297178	12	+	27260156	COLO741	viability	ACCTGTCCGACGCTGCCAACCGG	PRPH	ENSG00000135406	0.15635012666189652	[822]	[1438,1004,1096]	3	hSpCas9	negative selection	5992856
49296470	49296493	12	+	27260156	COLO741	viability	GCGCAAGATTGAGTCTCTGATGG	PRPH	ENSG00000135406	-0.44003397383906084	[396]	[530,216,384]	-7	hSpCas9	negative selection	5992857
49296990	49297013	12	-	27260156	CAL120	viability	CGATGCTCTCGTACTGCGCGCGG	PRPH	ENSG00000135406	-0.4714533749970062	[447]	[462,280,469]	-6	hSpCas9	negative selection	6049847
49297234	49297257	12	-	27260156	CAL120	viability	CCACCTCGCACGTTAGACTCTGG	PRPH	ENSG00000135406	-0.2486090313232714	[884]	[1084,1000,721]	-4	hSpCas9	negative selection	6049848
49297008	49297031	12	+	27260156	CAL120	viability	CATCGCCGCGAAGAACCTGCAGG	PRPH	ENSG00000135406	-0.06963895581041746	[376]	[486,417,441]	-1	hSpCas9	negative selection	6049849
49296458	49296481	12	-	27260156	CAL120	viability	CAATCTTGCGCTCTAGTTCCAGG	PRPH	ENSG00000135406	0.365346302230186	[631]	[1167,1205,693]	5	hSpCas9	negative selection	6114106
49297155	49297178	12	+	27260156	CAL120	viability	ACCTGTCCGACGCTGCCAACCGG	PRPH	ENSG00000135406	0.23104633883321868	[822]	[1568,1071,1022]	3	hSpCas9	negative selection	6114107
49296470	49296493	12	+	27260156	CAL120	viability	GCGCAAGATTGAGTCTCTGATGG	PRPH	ENSG00000135406	-0.5834396305042882	[396]	[483,300,228]	-7	hSpCas9	negative selection	6114108
49296990	49297013	12	-	27260156	CADOES1	viability	CGATGCTCTCGTACTGCGCGCGG	PRPH	ENSG00000135406	0.1080631630433968	[447]	[433,359,377,630]	1	hSpCas9	negative selection	6171098
49297234	49297257	12	-	27260156	CADOES1	viability	CCACCTCGCACGTTAGACTCTGG	PRPH	ENSG00000135406	-0.2813300182791073	[884]	[740,670,617,678]	-5	hSpCas9	negative selection	6171099
49297008	49297031	12	+	27260156	CADOES1	viability	CATCGCCGCGAAGAACCTGCAGG	PRPH	ENSG00000135406	0.537701389540018	[376]	[321,256,357,1121]	8	hSpCas9	negative selection	6171100
49296458	49296481	12	-	27260156	CADOES1	viability	CAATCTTGCGCTCTAGTTCCAGG	PRPH	ENSG00000135406	0.053500865768768224	[631]	[527,554,799,554]	0	hSpCas9	negative selection	6235357
49297155	49297178	12	+	27260156	CADOES1	viability	ACCTGTCCGACGCTGCCAACCGG	PRPH	ENSG00000135406	0.10074158527593935	[822]	[653,951,853,823]	1	hSpCas9	negative selection	6235358
49296470	49296493	12	+	27260156	CADOES1	viability	GCGCAAGATTGAGTCTCTGATGG	PRPH	ENSG00000135406	-0.17366139232487632	[396]	[383,317,337,266]	-3	hSpCas9	negative selection	6235359
49296990	49297013	12	-	27260156	EWS502	viability	CGATGCTCTCGTACTGCGCGCGG	PRPH	ENSG00000135406	0.014063361338350233	[447]	[418,475,583,441]	0	hSpCas9	negative selection	6292349
49297234	49297257	12	-	27260156	EWS502	viability	CCACCTCGCACGTTAGACTCTGG	PRPH	ENSG00000135406	-0.34616112979501357	[884]	[801,543,729,880]	-5	hSpCas9	negative selection	6292350
49297008	49297031	12	+	27260156	EWS502	viability	CATCGCCGCGAAGAACCTGCAGG	PRPH	ENSG00000135406	-0.10876884001728293	[376]	[267,465,263,497]	-2	hSpCas9	negative selection	6292351
49296458	49296481	12	-	27260156	EWS502	viability	CAATCTTGCGCTCTAGTTCCAGG	PRPH	ENSG00000135406	0.1758308433888311	[631]	[564,950,637,890]	3	hSpCas9	negative selection	6356608
49297155	49297178	12	+	27260156	EWS502	viability	ACCTGTCCGACGCTGCCAACCGG	PRPH	ENSG00000135406	0.14501502271503708	[822]	[811,929,1062,1075]	2	hSpCas9	negative selection	6356609
49296470	49296493	12	+	27260156	EWS502	viability	GCGCAAGATTGAGTCTCTGATGG	PRPH	ENSG00000135406	-0.36382069292147556	[396]	[359,281,281,382]	-6	hSpCas9	negative selection	6356610
49296990	49297013	12	-	27260156	EW8	viability	CGATGCTCTCGTACTGCGCGCGG	PRPH	ENSG00000135406	-0.20918257260700257	[447]	[387,375,236,275]	-4	hSpCas9	negative selection	6413600
49297234	49297257	12	-	27260156	EW8	viability	CCACCTCGCACGTTAGACTCTGG	PRPH	ENSG00000135406	-0.2148321528719943	[884]	[795,629,553,520]	-4	hSpCas9	negative selection	6413601
49297008	49297031	12	+	27260156	EW8	viability	CATCGCCGCGAAGAACCTGCAGG	PRPH	ENSG00000135406	-0.01644425801510835	[376]	[431,208,309,268]	0	hSpCas9	negative selection	6413602
49296458	49296481	12	-	27260156	EW8	viability	CAATCTTGCGCTCTAGTTCCAGG	PRPH	ENSG00000135406	0.0292165489346759	[631]	[471,478,558,566]	0	hSpCas9	negative selection	6477859
49297155	49297178	12	+	27260156	EW8	viability	ACCTGTCCGACGCTGCCAACCGG	PRPH	ENSG00000135406	0.16185291973702498	[822]	[609,754,878,700]	3	hSpCas9	negative selection	6477860
49296470	49296493	12	+	27260156	EW8	viability	GCGCAAGATTGAGTCTCTGATGG	PRPH	ENSG00000135406	-0.8632068672525279	[396]	[193,172,163,179]	-9	hSpCas9	negative selection	6477861
49296990	49297013	12	-	27260156	CORL105	viability	CGATGCTCTCGTACTGCGCGCGG	PRPH	ENSG00000135406	0.0036513344886249383	[447]	[435,577,489,588]	0	hSpCas9	negative selection	6534851
49297234	49297257	12	-	27260156	CORL105	viability	CCACCTCGCACGTTAGACTCTGG	PRPH	ENSG00000135406	-0.1386201486835802	[884]	[973,923,1073,814]	-3	hSpCas9	negative selection	6534852
49297008	49297031	12	+	27260156	CORL105	viability	CATCGCCGCGAAGAACCTGCAGG	PRPH	ENSG00000135406	0.11363868045658684	[376]	[466,596,335,484]	2	hSpCas9	negative selection	6534853
49296458	49296481	12	-	27260156	CORL105	viability	CAATCTTGCGCTCTAGTTCCAGG	PRPH	ENSG00000135406	0.083050012241001	[631]	[762,626,869,889]	1	hSpCas9	negative selection	6599110
49297155	49297178	12	+	27260156	CORL105	viability	ACCTGTCCGACGCTGCCAACCGG	PRPH	ENSG00000135406	0.40410688758936475	[822]	[1191,1197,1441,1291]	7	hSpCas9	negative selection	6599111
49296470	49296493	12	+	27260156	CORL105	viability	GCGCAAGATTGAGTCTCTGATGG	PRPH	ENSG00000135406	-0.04236465479472967	[396]	[483,588,399,322]	-1	hSpCas9	negative selection	6599112
49296990	49297013	12	-	27260156	HS294T	viability	CGATGCTCTCGTACTGCGCGCGG	PRPH	ENSG00000135406	-0.2618456923298732	[447]	[154,113,160,147]	-4	hSpCas9	negative selection	6656102
49297234	49297257	12	-	27260156	HS294T	viability	CCACCTCGCACGTTAGACTCTGG	PRPH	ENSG00000135406	-0.21640606899082615	[884]	[270,283,358,259]	-3	hSpCas9	negative selection	6656103
49297008	49297031	12	+	27260156	HS294T	viability	CATCGCCGCGAAGAACCTGCAGG	PRPH	ENSG00000135406	0.6682643265663764	[376]	[304,232,141,239]	8	hSpCas9	negative selection	6656104
49296458	49296481	12	-	27260156	HS294T	viability	CAATCTTGCGCTCTAGTTCCAGG	PRPH	ENSG00000135406	0.6759902445309602	[631]	[370,501,241,453]	8	hSpCas9	negative selection	6720361
49297155	49297178	12	+	27260156	HS294T	viability	ACCTGTCCGACGCTGCCAACCGG	PRPH	ENSG00000135406	0.7802277524276515	[822]	[569,433,723,439]	8	hSpCas9	negative selection	6720362
49296470	49296493	12	+	27260156	HS294T	viability	GCGCAAGATTGAGTCTCTGATGG	PRPH	ENSG00000135406	0.04194300839169793	[396]	[233,157,109,114]	0	hSpCas9	negative selection	6720363
49296990	49297013	12	-	27260156	HCC44	viability	CGATGCTCTCGTACTGCGCGCGG	PRPH	ENSG00000135406	-0.1445394026929943	[447]	[380,341,664,485]	-2	hSpCas9	negative selection	6777353
49297234	49297257	12	-	27260156	HCC44	viability	CCACCTCGCACGTTAGACTCTGG	PRPH	ENSG00000135406	0.17512947633227782	[884]	[1009,1355,1104,996]	2	hSpCas9	negative selection	6777354
49297008	49297031	12	+	27260156	HCC44	viability	CATCGCCGCGAAGAACCTGCAGG	PRPH	ENSG00000135406	0.05953664261926489	[376]	[475,396,435,471]	0	hSpCas9	negative selection	6777355
49296458	49296481	12	-	27260156	HCC44	viability	CAATCTTGCGCTCTAGTTCCAGG	PRPH	ENSG00000135406	0.4642160945215246	[631]	[769,744,1688,871]	7	hSpCas9	negative selection	6841612
49297155	49297178	12	+	27260156	HCC44	viability	ACCTGTCCGACGCTGCCAACCGG	PRPH	ENSG00000135406	0.2724253131632095	[822]	[1083,1069,1224,1129]	4	hSpCas9	negative selection	6841613
49296470	49296493	12	+	27260156	HCC44	viability	GCGCAAGATTGAGTCTCTGATGG	PRPH	ENSG00000135406	-1.0060634307870493	[396]	[315,70,284,259]	-8	hSpCas9	negative selection	6841614
49296990	49297013	12	-	27260156	G402	viability	CGATGCTCTCGTACTGCGCGCGG	PRPH	ENSG00000135406	0.26509255028392037	[447]	[756,658,636,589]	3	hSpCas9	negative selection	6898604
49297234	49297257	12	-	27260156	G402	viability	CCACCTCGCACGTTAGACTCTGG	PRPH	ENSG00000135406	0.10866958756137224	[884]	[812,1122,1694,977]	1	hSpCas9	negative selection	6898605
49297008	49297031	12	+	27260156	G402	viability	CATCGCCGCGAAGAACCTGCAGG	PRPH	ENSG00000135406	-0.13496857430625653	[376]	[633,342,500,231]	-2	hSpCas9	negative selection	6898606
49296458	49296481	12	-	27260156	G402	viability	CAATCTTGCGCTCTAGTTCCAGG	PRPH	ENSG00000135406	0.2672877341798114	[631]	[1181,1203,497,879]	3	hSpCas9	negative selection	6962863
49297155	49297178	12	+	27260156	G402	viability	ACCTGTCCGACGCTGCCAACCGG	PRPH	ENSG00000135406	0.6589766722518318	[822]	[1560,950,2220,1563]	7	hSpCas9	negative selection	6962864
49296470	49296493	12	+	27260156	G402	viability	GCGCAAGATTGAGTCTCTGATGG	PRPH	ENSG00000135406	0.058980204432110495	[396]	[935,429,340,373]	0	hSpCas9	negative selection	6962865
49296990	49297013	12	-	27260156	L33	viability	CGATGCTCTCGTACTGCGCGCGG	PRPH	ENSG00000135406	-0.07146121766144652	[447]	[393,165,276,465]	-2	hSpCas9	negative selection	7019855
49297234	49297257	12	-	27260156	L33	viability	CCACCTCGCACGTTAGACTCTGG	PRPH	ENSG00000135406	-0.012388784775385075	[884]	[1121,319,468,853]	0	hSpCas9	negative selection	7019856
49297008	49297031	12	+	27260156	L33	viability	CATCGCCGCGAAGAACCTGCAGG	PRPH	ENSG00000135406	-0.04345627243082034	[376]	[377,158,189,393]	-1	hSpCas9	negative selection	7019857
49296458	49296481	12	-	27260156	L33	viability	CAATCTTGCGCTCTAGTTCCAGG	PRPH	ENSG00000135406	-0.13251094843371258	[631]	[526,175,477,590]	-3	hSpCas9	negative selection	7084114
49297155	49297178	12	+	27260156	L33	viability	ACCTGTCCGACGCTGCCAACCGG	PRPH	ENSG00000135406	0.35599830535270804	[822]	[998,412,718,1063]	7	hSpCas9	negative selection	7084115
49296470	49296493	12	+	27260156	L33	viability	GCGCAAGATTGAGTCTCTGATGG	PRPH	ENSG00000135406	-0.01882781919243065	[396]	[428,136,267,376]	0	hSpCas9	negative selection	7084116
49296990	49297013	12	-	27260156	K562	viability	CGATGCTCTCGTACTGCGCGCGG	PRPH	ENSG00000135406	-0.31542731290018117	[447]	[288,475,241,279]	-4	hSpCas9	negative selection	7141106
49297234	49297257	12	-	27260156	K562	viability	CCACCTCGCACGTTAGACTCTGG	PRPH	ENSG00000135406	0.04083068190231243	[884]	[767,516,685,1192]	0	hSpCas9	negative selection	7141107
49297008	49297031	12	+	27260156	K562	viability	CATCGCCGCGAAGAACCTGCAGG	PRPH	ENSG00000135406	0.16207085709885388	[376]	[631,482,178,243]	2	hSpCas9	negative selection	7141108
49296458	49296481	12	-	27260156	K562	viability	CAATCTTGCGCTCTAGTTCCAGG	PRPH	ENSG00000135406	0.36962064389268107	[631]	[627,1009,836,458]	4	hSpCas9	negative selection	7205365
49297155	49297178	12	+	27260156	K562	viability	ACCTGTCCGACGCTGCCAACCGG	PRPH	ENSG00000135406	0.3787612412665311	[822]	[658,1055,1316,765]	5	hSpCas9	negative selection	7205366
49296470	49296493	12	+	27260156	K562	viability	GCGCAAGATTGAGTCTCTGATGG	PRPH	ENSG00000135406	-0.5282707908358228	[396]	[283,330,200,175]	-6	hSpCas9	negative selection	7205367
49296990	49297013	12	-	27260156	HT29	viability	CGATGCTCTCGTACTGCGCGCGG	PRPH	ENSG00000135406	0.08822314942273171	[447]	[683,623,575,454]	1	hSpCas9	negative selection	7262357
49297234	49297257	12	-	27260156	HT29	viability	CCACCTCGCACGTTAGACTCTGG	PRPH	ENSG00000135406	-0.12413972159519926	[884]	[1122,803,1030,978]	-3	hSpCas9	negative selection	7262358
49297008	49297031	12	+	27260156	HT29	viability	CATCGCCGCGAAGAACCTGCAGG	PRPH	ENSG00000135406	-0.01017270727192049	[376]	[507,439,490,388]	0	hSpCas9	negative selection	7262359
49296458	49296481	12	-	27260156	HT29	viability	CAATCTTGCGCTCTAGTTCCAGG	PRPH	ENSG00000135406	-0.08972149168601634	[631]	[668,783,719,711]	-2	hSpCas9	negative selection	7326616
49297155	49297178	12	+	27260156	HT29	viability	ACCTGTCCGACGCTGCCAACCGG	PRPH	ENSG00000135406	0.32800999990991486	[822]	[1467,1493,1075,1039]	6	hSpCas9	negative selection	7326617
49296470	49296493	12	+	27260156	HT29	viability	GCGCAAGATTGAGTCTCTGATGG	PRPH	ENSG00000135406	-0.1261376861120066	[396]	[547,489,469,288]	-3	hSpCas9	negative selection	7326618
49296990	49297013	12	-	27260156	MHHES1	viability	CGATGCTCTCGTACTGCGCGCGG	PRPH	ENSG00000135406	-0.2880084575116606	[447]	[346,423,453,411]	-5	hSpCas9	negative selection	7383608
49297234	49297257	12	-	27260156	MHHES1	viability	CCACCTCGCACGTTAGACTCTGG	PRPH	ENSG00000135406	0.03792520273466782	[884]	[1108,1285,1145,653]	0	hSpCas9	negative selection	7383609
49297008	49297031	12	+	27260156	MHHES1	viability	CATCGCCGCGAAGAACCTGCAGG	PRPH	ENSG00000135406	0.37919050499346907	[376]	[591,886,385,403]	6	hSpCas9	negative selection	7383610
49296458	49296481	12	-	27260156	MHHES1	viability	CAATCTTGCGCTCTAGTTCCAGG	PRPH	ENSG00000135406	0.03521806522548471	[631]	[881,665,887,525]	0	hSpCas9	negative selection	7447867
49297155	49297178	12	+	27260156	MHHES1	viability	ACCTGTCCGACGCTGCCAACCGG	PRPH	ENSG00000135406	0.27203707960538237	[822]	[1282,1101,1110,1000]	5	hSpCas9	negative selection	7447868
49296470	49296493	12	+	27260156	MHHES1	viability	GCGCAAGATTGAGTCTCTGATGG	PRPH	ENSG00000135406	-0.43664018611938915	[396]	[337,380,343,270]	-7	hSpCas9	negative selection	7447869
49296990	49297013	12	-	27260156	MEWO	viability	CGATGCTCTCGTACTGCGCGCGG	PRPH	ENSG00000135406	-0.046127150059684555	[447]	[435,315,471]	-1	hSpCas9	negative selection	7504859
49297234	49297257	12	-	27260156	MEWO	viability	CCACCTCGCACGTTAGACTCTGG	PRPH	ENSG00000135406	0.0804882281827497	[884]	[1115,636,920]	1	hSpCas9	negative selection	7504860
49297008	49297031	12	+	27260156	MEWO	viability	CATCGCCGCGAAGAACCTGCAGG	PRPH	ENSG00000135406	0.11552432288550715	[376]	[324,419,389]	2	hSpCas9	negative selection	7504861
49296458	49296481	12	-	27260156	MEWO	viability	CAATCTTGCGCTCTAGTTCCAGG	PRPH	ENSG00000135406	0.07175188118587361	[631]	[785,625,483]	1	hSpCas9	negative selection	7569118
49297155	49297178	12	+	27260156	MEWO	viability	ACCTGTCCGACGCTGCCAACCGG	PRPH	ENSG00000135406	0.22104606780324754	[822]	[877,979,829]	5	hSpCas9	negative selection	7569119
49296470	49296493	12	+	27260156	MEWO	viability	GCGCAAGATTGAGTCTCTGATGG	PRPH	ENSG00000135406	0.04133431183050709	[396]	[411,448,290]	0	hSpCas9	negative selection	7569120
49296990	49297013	12	-	27260156	LNCAPCLONEFGC	viability	CGATGCTCTCGTACTGCGCGCGG	PRPH	ENSG00000135406	0.13524285784550555	[447]	[290,401,671,456]	2	hSpCas9	negative selection	7626110
49297234	49297257	12	-	27260156	LNCAPCLONEFGC	viability	CCACCTCGCACGTTAGACTCTGG	PRPH	ENSG00000135406	0.11938168590771159	[884]	[765,790,1159,815]	1	hSpCas9	negative selection	7626111
49297008	49297031	12	+	27260156	LNCAPCLONEFGC	viability	CATCGCCGCGAAGAACCTGCAGG	PRPH	ENSG00000135406	0.12194480269047825	[376]	[511,267,395,317]	2	hSpCas9	negative selection	7626112
49296458	49296481	12	-	27260156	LNCAPCLONEFGC	viability	CAATCTTGCGCTCTAGTTCCAGG	PRPH	ENSG00000135406	0.260013398399025	[631]	[630,624,881,637]	4	hSpCas9	negative selection	7690369
49297155	49297178	12	+	27260156	LNCAPCLONEFGC	viability	ACCTGTCCGACGCTGCCAACCGG	PRPH	ENSG00000135406	0.08431272190368688	[822]	[805,641,887,848]	1	hSpCas9	negative selection	7690370
49296470	49296493	12	+	27260156	LNCAPCLONEFGC	viability	GCGCAAGATTGAGTCTCTGATGG	PRPH	ENSG00000135406	0.06069864448676271	[396]	[291,322,562,354]	0	hSpCas9	negative selection	7690371
49296990	49297013	12	-	27260156	PANC0327	viability	CGATGCTCTCGTACTGCGCGCGG	PRPH	ENSG00000135406	-0.09191767446926914	[447]	[346,313,406,430]	-1	hSpCas9	negative selection	7747361
49297234	49297257	12	-	27260156	PANC0327	viability	CCACCTCGCACGTTAGACTCTGG	PRPH	ENSG00000135406	-0.2863391674804421	[884]	[765,461,733,649]	-4	hSpCas9	negative selection	7747362
49297008	49297031	12	+	27260156	PANC0327	viability	CATCGCCGCGAAGAACCTGCAGG	PRPH	ENSG00000135406	0.3851155553221414	[376]	[556,340,628,244]	6	hSpCas9	negative selection	7747363
49296458	49296481	12	-	27260156	PANC0327	viability	CAATCTTGCGCTCTAGTTCCAGG	PRPH	ENSG00000135406	0.0508664511917728	[631]	[449,526,500,843]	0	hSpCas9	negative selection	7811620
49297155	49297178	12	+	27260156	PANC0327	viability	ACCTGTCCGACGCTGCCAACCGG	PRPH	ENSG00000135406	-0.018530884826349237	[822]	[1074,473,404,992]	0	hSpCas9	negative selection	7811621
49296470	49296493	12	+	27260156	PANC0327	viability	GCGCAAGATTGAGTCTCTGATGG	PRPH	ENSG00000135406	-0.3205332442755944	[396]	[245,334,385,152]	-5	hSpCas9	negative selection	7811622
49296990	49297013	12	-	27260156	NCIH2009	viability	CGATGCTCTCGTACTGCGCGCGG	PRPH	ENSG00000135406	0.024097412649174157	[447]	[839,611,496]	0	hSpCas9	negative selection	7868612
49297234	49297257	12	-	27260156	NCIH2009	viability	CCACCTCGCACGTTAGACTCTGG	PRPH	ENSG00000135406	0.09692796031582052	[884]	[1608,1081,1334]	1	hSpCas9	negative selection	7868613
49297008	49297031	12	+	27260156	NCIH2009	viability	CATCGCCGCGAAGAACCTGCAGG	PRPH	ENSG00000135406	0.6236763102617313	[376]	[1028,664,784]	8	hSpCas9	negative selection	7868614
49296458	49296481	12	-	27260156	NCIH2009	viability	CAATCTTGCGCTCTAGTTCCAGG	PRPH	ENSG00000135406	-0.22862628158827772	[631]	[917,808,563]	-3	hSpCas9	negative selection	7932871
49297155	49297178	12	+	27260156	NCIH2009	viability	ACCTGTCCGACGCTGCCAACCGG	PRPH	ENSG00000135406	0.34890241567346814	[822]	[1336,1666,1357]	5	hSpCas9	negative selection	7932872
49296470	49296493	12	+	27260156	NCIH2009	viability	GCGCAAGATTGAGTCTCTGATGG	PRPH	ENSG00000135406	-1.153960264403259	[396]	[345,165,255]	-8	hSpCas9	negative selection	7932873
49296990	49297013	12	-	27260156	NCIH1373	viability	CGATGCTCTCGTACTGCGCGCGG	PRPH	ENSG00000135406	-0.3341511119571277	[447]	[627,422,272,77]	-3	hSpCas9	negative selection	7989863
49297234	49297257	12	-	27260156	NCIH1373	viability	CCACCTCGCACGTTAGACTCTGG	PRPH	ENSG00000135406	0.19194879170957335	[884]	[1158,964,919,402]	2	hSpCas9	negative selection	7989864
49297008	49297031	12	+	27260156	NCIH1373	viability	CATCGCCGCGAAGAACCTGCAGG	PRPH	ENSG00000135406	0.7148467069693788	[376]	[529,315,1235,181]	7	hSpCas9	negative selection	7989865
49296458	49296481	12	-	27260156	NCIH1373	viability	CAATCTTGCGCTCTAGTTCCAGG	PRPH	ENSG00000135406	-0.029907269894655808	[631]	[927,730,565,150]	0	hSpCas9	negative selection	8054122
49297155	49297178	12	+	27260156	NCIH1373	viability	ACCTGTCCGACGCTGCCAACCGG	PRPH	ENSG00000135406	-0.4968903371543512	[822]	[744,475,829,153]	-5	hSpCas9	negative selection	8054123
49296470	49296493	12	+	27260156	NCIH1373	viability	GCGCAAGATTGAGTCTCTGATGG	PRPH	ENSG00000135406	-1.6295705837301024	[396]	[229,107,137,29]	-9	hSpCas9	negative selection	8054124
49296990	49297013	12	-	27260156	PATU8902	viability	CGATGCTCTCGTACTGCGCGCGG	PRPH	ENSG00000135406	0.1072832453707879	[447]	[438,1057,491,754]	1	hSpCas9	negative selection	8111114
49297234	49297257	12	-	27260156	PATU8902	viability	CCACCTCGCACGTTAGACTCTGG	PRPH	ENSG00000135406	-0.08245890475744566	[884]	[748,1471,1097,1376]	-1	hSpCas9	negative selection	8111115
49297008	49297031	12	+	27260156	PATU8902	viability	CATCGCCGCGAAGAACCTGCAGG	PRPH	ENSG00000135406	0.033082341059800846	[376]	[526,782,411,444]	0	hSpCas9	negative selection	8111116
49296458	49296481	12	-	27260156	PATU8902	viability	CAATCTTGCGCTCTAGTTCCAGG	PRPH	ENSG00000135406	0.33279996624359626	[631]	[1423,983,792,1327]	3	hSpCas9	negative selection	8175373
49297155	49297178	12	+	27260156	PATU8902	viability	ACCTGTCCGACGCTGCCAACCGG	PRPH	ENSG00000135406	-0.15122286843215382	[822]	[1160,750,1091,1106]	-1	hSpCas9	negative selection	8175374
49296470	49296493	12	+	27260156	PATU8902	viability	GCGCAAGATTGAGTCTCTGATGG	PRPH	ENSG00000135406	-1.074305239313521	[396]	[238,240,144,479]	-7	hSpCas9	negative selection	8175375
49296990	49297013	12	-	27260156	PANC1	viability	CGATGCTCTCGTACTGCGCGCGG	PRPH	ENSG00000135406	0.02767366989438407	[447]	[452,362,381,361]	0	hSpCas9	negative selection	8232365
49297234	49297257	12	-	27260156	PANC1	viability	CCACCTCGCACGTTAGACTCTGG	PRPH	ENSG00000135406	-0.05892177996500858	[884]	[633,877,869,582]	-1	hSpCas9	negative selection	8232366
49297008	49297031	12	+	27260156	PANC1	viability	CATCGCCGCGAAGAACCTGCAGG	PRPH	ENSG00000135406	0.041579806212447334	[376]	[212,505,329,318]	0	hSpCas9	negative selection	8232367
49296458	49296481	12	-	27260156	PANC1	viability	CAATCTTGCGCTCTAGTTCCAGG	PRPH	ENSG00000135406	-0.029170720477692147	[631]	[493,627,497,520]	0	hSpCas9	negative selection	8296624
49297155	49297178	12	+	27260156	PANC1	viability	ACCTGTCCGACGCTGCCAACCGG	PRPH	ENSG00000135406	0.47804981548887215	[822]	[879,1398,801,934]	7	hSpCas9	negative selection	8296625
49296470	49296493	12	+	27260156	PANC1	viability	GCGCAAGATTGAGTCTCTGATGG	PRPH	ENSG00000135406	-0.12505438652853973	[396]	[215,432,407,229]	-2	hSpCas9	negative selection	8296626
49296990	49297013	12	-	27260156	PANC0813	viability	CGATGCTCTCGTACTGCGCGCGG	PRPH	ENSG00000135406	0.22465643625900023	[447]	[752,429,831,465]	3	hSpCas9	negative selection	8353616
49297234	49297257	12	-	27260156	PANC0813	viability	CCACCTCGCACGTTAGACTCTGG	PRPH	ENSG00000135406	-0.026542570253489384	[884]	[1162,1058,1209,681]	0	hSpCas9	negative selection	8353617
49297008	49297031	12	+	27260156	PANC0813	viability	CATCGCCGCGAAGAACCTGCAGG	PRPH	ENSG00000135406	0.3630771963817464	[376]	[522,635,769,356]	6	hSpCas9	negative selection	8353618
49296458	49296481	12	-	27260156	PANC0813	viability	CAATCTTGCGCTCTAGTTCCAGG	PRPH	ENSG00000135406	-0.018084727366932396	[631]	[591,895,628,796]	0	hSpCas9	negative selection	8417875
49297155	49297178	12	+	27260156	PANC0813	viability	ACCTGTCCGACGCTGCCAACCGG	PRPH	ENSG00000135406	0.38195898500934145	[822]	[1213,1288,1411,1125]	6	hSpCas9	negative selection	8417876
49296470	49296493	12	+	27260156	PANC0813	viability	GCGCAAGATTGAGTCTCTGATGG	PRPH	ENSG00000135406	-0.27574142772637755	[396]	[335,378,334,479]	-4	hSpCas9	negative selection	8417877
49296990	49297013	12	-	27260156	RDES	viability	CGATGCTCTCGTACTGCGCGCGG	PRPH	ENSG00000135406	0.23380904559754967	[447]	[523,608,702,585]	4	hSpCas9	negative selection	8474867
49297234	49297257	12	-	27260156	RDES	viability	CCACCTCGCACGTTAGACTCTGG	PRPH	ENSG00000135406	-0.07680298625179416	[884]	[627,996,1077,1247]	-1	hSpCas9	negative selection	8474868
49297008	49297031	12	+	27260156	RDES	viability	CATCGCCGCGAAGAACCTGCAGG	PRPH	ENSG00000135406	-0.05402057152772444	[376]	[396,407,363,503]	-1	hSpCas9	negative selection	8474869
49296458	49296481	12	-	27260156	RDES	viability	CAATCTTGCGCTCTAGTTCCAGG	PRPH	ENSG00000135406	-0.027917305602695175	[631]	[636,701,686,837]	0	hSpCas9	negative selection	8539126
49297155	49297178	12	+	27260156	RDES	viability	ACCTGTCCGACGCTGCCAACCGG	PRPH	ENSG00000135406	0.09292268419838268	[822]	[815,879,1212,1187]	1	hSpCas9	negative selection	8539127
49296470	49296493	12	+	27260156	RDES	viability	GCGCAAGATTGAGTCTCTGATGG	PRPH	ENSG00000135406	-0.6621214254630803	[396]	[237,214,345,380]	-8	hSpCas9	negative selection	8539128
49296990	49297013	12	-	27260156	PC3	viability	CGATGCTCTCGTACTGCGCGCGG	PRPH	ENSG00000135406	0.29672431001593025	[447]	[258,616,666,787]	6	hSpCas9	negative selection	8596118
49297234	49297257	12	-	27260156	PC3	viability	CCACCTCGCACGTTAGACTCTGG	PRPH	ENSG00000135406	-0.14218786799846772	[884]	[464,932,1334,734]	-3	hSpCas9	negative selection	8596119
49297008	49297031	12	+	27260156	PC3	viability	CATCGCCGCGAAGAACCTGCAGG	PRPH	ENSG00000135406	0.0195194793499211	[376]	[182,391,845,338]	0	hSpCas9	negative selection	8596120
49296458	49296481	12	-	27260156	PC3	viability	CAATCTTGCGCTCTAGTTCCAGG	PRPH	ENSG00000135406	-0.055458442696950105	[631]	[352,457,1214,705]	-1	hSpCas9	negative selection	8660377
49297155	49297178	12	+	27260156	PC3	viability	ACCTGTCCGACGCTGCCAACCGG	PRPH	ENSG00000135406	0.39817330956272734	[822]	[620,976,2008,1194]	8	hSpCas9	negative selection	8660378
49296470	49296493	12	+	27260156	PC3	viability	GCGCAAGATTGAGTCTCTGATGG	PRPH	ENSG00000135406	0.055102651837243694	[396]	[349,401,679,285]	1	hSpCas9	negative selection	8660379
49296990	49297013	12	-	27260156	PATU8988T	viability	CGATGCTCTCGTACTGCGCGCGG	PRPH	ENSG00000135406	-0.10110123225297225	[447]	[258,399,509,446]	-2	hSpCas9	negative selection	8717369
49297234	49297257	12	-	27260156	PATU8988T	viability	CCACCTCGCACGTTAGACTCTGG	PRPH	ENSG00000135406	-0.22442695118251155	[884]	[806,772,563,794]	-4	hSpCas9	negative selection	8717370
49297008	49297031	12	+	27260156	PATU8988T	viability	CATCGCCGCGAAGAACCTGCAGG	PRPH	ENSG00000135406	-0.4125400714313788	[376]	[205,354,349,182]	-6	hSpCas9	negative selection	8717371
49296458	49296481	12	-	27260156	PATU8988T	viability	CAATCTTGCGCTCTAGTTCCAGG	PRPH	ENSG00000135406	-0.0629477509977654	[631]	[735,498,593,493]	-1	hSpCas9	negative selection	8781628
49297155	49297178	12	+	27260156	PATU8988T	viability	ACCTGTCCGACGCTGCCAACCGG	PRPH	ENSG00000135406	0.3951762744736882	[822]	[1081,1236,887,991]	6	hSpCas9	negative selection	8781629
49296470	49296493	12	+	27260156	PATU8988T	viability	GCGCAAGATTGAGTCTCTGATGG	PRPH	ENSG00000135406	-0.35221771966280935	[396]	[341,209,232,418]	-5	hSpCas9	negative selection	8781630
49296990	49297013	12	-	27260156	T47D	viability	CGATGCTCTCGTACTGCGCGCGG	PRPH	ENSG00000135406	-0.007291510521812358	[447]	[558,399,589,537]	0	hSpCas9	negative selection	8838620
49297234	49297257	12	-	27260156	T47D	viability	CCACCTCGCACGTTAGACTCTGG	PRPH	ENSG00000135406	-0.256274274430597	[884]	[952,754,868,885]	-5	hSpCas9	negative selection	8838621
49297008	49297031	12	+	27260156	T47D	viability	CATCGCCGCGAAGAACCTGCAGG	PRPH	ENSG00000135406	-0.16352335634175164	[376]	[393,401,333,439]	-4	hSpCas9	negative selection	8838622
49296458	49296481	12	-	27260156	T47D	viability	CAATCTTGCGCTCTAGTTCCAGG	PRPH	ENSG00000135406	0.0197115199261938	[631]	[786,732,762,701]	0	hSpCas9	negative selection	8902879
49297155	49297178	12	+	27260156	T47D	viability	ACCTGTCCGACGCTGCCAACCGG	PRPH	ENSG00000135406	0.07716304329712043	[822]	[986,855,1037,1182]	1	hSpCas9	negative selection	8902880
49296470	49296493	12	+	27260156	T47D	viability	GCGCAAGATTGAGTCTCTGATGG	PRPH	ENSG00000135406	-0.37852019618143173	[396]	[337,367,313,403]	-7	hSpCas9	negative selection	8902881
49296990	49297013	12	-	27260156	SU8686	viability	CGATGCTCTCGTACTGCGCGCGG	PRPH	ENSG00000135406	-0.10987202515630852	[447]	[377,416,329,539]	-2	hSpCas9	negative selection	8959871
49297234	49297257	12	-	27260156	SU8686	viability	CCACCTCGCACGTTAGACTCTGG	PRPH	ENSG00000135406	0.10689408964627745	[884]	[830,721,980,1346]	1	hSpCas9	negative selection	8959872
49297008	49297031	12	+	27260156	SU8686	viability	CATCGCCGCGAAGAACCTGCAGG	PRPH	ENSG00000135406	0.39410662056168133	[376]	[332,469,559,645]	6	hSpCas9	negative selection	8959873
49296458	49296481	12	-	27260156	SU8686	viability	CAATCTTGCGCTCTAGTTCCAGG	PRPH	ENSG00000135406	-0.2286977454132584	[631]	[497,552,508,583]	-4	hSpCas9	negative selection	9024130
49297155	49297178	12	+	27260156	SU8686	viability	ACCTGTCCGACGCTGCCAACCGG	PRPH	ENSG00000135406	0.2010424615335329	[822]	[987,772,928,1095]	3	hSpCas9	negative selection	9024131
49296470	49296493	12	+	27260156	SU8686	viability	GCGCAAGATTGAGTCTCTGATGG	PRPH	ENSG00000135406	-0.46296845724528435	[396]	[277,250,286,337]	-6	hSpCas9	negative selection	9024132
49296990	49297013	12	-	27260156	SKES1	viability	CGATGCTCTCGTACTGCGCGCGG	PRPH	ENSG00000135406	0.08504151463948471	[447]	[586,578,427,341]	1	hSpCas9	negative selection	9081122
49297234	49297257	12	-	27260156	SKES1	viability	CCACCTCGCACGTTAGACTCTGG	PRPH	ENSG00000135406	-0.19187281331040318	[884]	[879,713,1039,487]	-4	hSpCas9	negative selection	9081123
49297008	49297031	12	+	27260156	SKES1	viability	CATCGCCGCGAAGAACCTGCAGG	PRPH	ENSG00000135406	-0.13859448838057076	[376]	[257,332,320,427]	-3	hSpCas9	negative selection	9081124
49296458	49296481	12	-	27260156	SKES1	viability	CAATCTTGCGCTCTAGTTCCAGG	PRPH	ENSG00000135406	-0.16622019656768106	[631]	[520,672,504,551]	-4	hSpCas9	negative selection	9145381
49297155	49297178	12	+	27260156	SKES1	viability	ACCTGTCCGACGCTGCCAACCGG	PRPH	ENSG00000135406	0.021862734063054945	[822]	[910,915,907,633]	0	hSpCas9	negative selection	9145382
49296470	49296493	12	+	27260156	SKES1	viability	GCGCAAGATTGAGTCTCTGATGG	PRPH	ENSG00000135406	-0.10936067996771182	[396]	[427,382,361,308]	-2	hSpCas9	negative selection	9145383
49296990	49297013	12	-	27260156	TOV112D	viability	CGATGCTCTCGTACTGCGCGCGG	PRPH	ENSG00000135406	0.011498098066821047	[447]	[680,410,472,257]	0	hSpCas9	negative selection	9202373
49297234	49297257	12	-	27260156	TOV112D	viability	CCACCTCGCACGTTAGACTCTGG	PRPH	ENSG00000135406	-0.02292109364229289	[884]	[914,1259,679,735]	0	hSpCas9	negative selection	9202374
49297008	49297031	12	+	27260156	TOV112D	viability	CATCGCCGCGAAGAACCTGCAGG	PRPH	ENSG00000135406	-0.216895411886662	[376]	[401,395,200,323]	-4	hSpCas9	negative selection	9202375
49296458	49296481	12	-	27260156	TOV112D	viability	CAATCTTGCGCTCTAGTTCCAGG	PRPH	ENSG00000135406	-0.10605405550500752	[631]	[474,934,416,599]	-2	hSpCas9	negative selection	9266632
49297155	49297178	12	+	27260156	TOV112D	viability	ACCTGTCCGACGCTGCCAACCGG	PRPH	ENSG00000135406	0.004598553385731674	[822]	[835,906,693,887]	0	hSpCas9	negative selection	9266633
49296470	49296493	12	+	27260156	TOV112D	viability	GCGCAAGATTGAGTCTCTGATGG	PRPH	ENSG00000135406	-0.14382009310443777	[396]	[374,403,308,362]	-3	hSpCas9	negative selection	9266634
49296990	49297013	12	-	27260156	TC71	viability	CGATGCTCTCGTACTGCGCGCGG	PRPH	ENSG00000135406	0.040730107867518656	[447]	[521,488,480,482]	1	hSpCas9	negative selection	9323624
49297234	49297257	12	-	27260156	TC71	viability	CCACCTCGCACGTTAGACTCTGG	PRPH	ENSG00000135406	-0.12261046669151499	[884]	[968,768,924,814]	-3	hSpCas9	negative selection	9323625
49297008	49297031	12	+	27260156	TC71	viability	CATCGCCGCGAAGAACCTGCAGG	PRPH	ENSG00000135406	-0.21600727332858521	[376]	[272,341,434,339]	-5	hSpCas9	negative selection	9323626
49296458	49296481	12	-	27260156	TC71	viability	CAATCTTGCGCTCTAGTTCCAGG	PRPH	ENSG00000135406	-0.021971650689813493	[631]	[681,698,601,688]	0	hSpCas9	negative selection	9387883
49297155	49297178	12	+	27260156	TC71	viability	ACCTGTCCGACGCTGCCAACCGG	PRPH	ENSG00000135406	0.24978738254990263	[822]	[950,1195,1047,999]	6	hSpCas9	negative selection	9387884
49296470	49296493	12	+	27260156	TC71	viability	GCGCAAGATTGAGTCTCTGATGG	PRPH	ENSG00000135406	-0.08555082595165514	[396]	[436,392,425,342]	-2	hSpCas9	negative selection	9387885
49296990	49297013	12	-	27260156	TC32	viability	CGATGCTCTCGTACTGCGCGCGG	PRPH	ENSG00000135406	0.11165757792200756	[447]	[466,378,521,461]	2	hSpCas9	negative selection	9444875
49297234	49297257	12	-	27260156	TC32	viability	CCACCTCGCACGTTAGACTCTGG	PRPH	ENSG00000135406	-0.021426697998442212	[884]	[888,466,1141,918]	0	hSpCas9	negative selection	9444876
49297008	49297031	12	+	27260156	TC32	viability	CATCGCCGCGAAGAACCTGCAGG	PRPH	ENSG00000135406	0.038335325789229324	[376]	[294,367,469,321]	0	hSpCas9	negative selection	9444877
49296458	49296481	12	-	27260156	TC32	viability	CAATCTTGCGCTCTAGTTCCAGG	PRPH	ENSG00000135406	0.22266961496494037	[631]	[528,684,804,755]	4	hSpCas9	negative selection	9509134
49297155	49297178	12	+	27260156	TC32	viability	ACCTGTCCGACGCTGCCAACCGG	PRPH	ENSG00000135406	0.16531497292357	[822]	[764,714,1001,1037]	3	hSpCas9	negative selection	9509135
49296470	49296493	12	+	27260156	TC32	viability	GCGCAAGATTGAGTCTCTGATGG	PRPH	ENSG00000135406	0.16146358992484822	[396]	[348,485,376,402]	3	hSpCas9	negative selection	9509136
49295475	49295498	12	-	27869803	HPAFII	viability after 27 days	CTGCTTCTCGTTGCTGCGCGTGG	PRPH	ENSG00000135406	0.8290933430740723	[258]	[368,135,NaN]	6	hSpCas9	negative selection	9546950
49296217	49296240	12	+	27869803	HPAFII	viability after 27 days	CAACCTCGTGCTCTTCCGCAAGG	PRPH	ENSG00000135406	0.4551475908789753	[208]	[130,166,NaN]	3	hSpCas9	negative selection	9546951
49296455	49296478	12	-	27869803	HPAFII	viability after 27 days	TCTTGCGCTCTAGTTCCAGGCGG	PRPH	ENSG00000135406	-2.875152909941523	[169]	[3,18,NaN]	-9	hSpCas9	negative selection	9546952
49296990	49297013	12	-	27869803	HPAFII	viability after 27 days	CGATGCTCTCGTACTGCGCGCGG	PRPH	ENSG00000135406	-1.208275216492749	[174]	[83,2,NaN]	-7	hSpCas9	negative selection	9546953
49297234	49297257	12	+	27869803	HPAFII	viability after 27 days	CCAGAGTCTAACGTGCGAGGTGG	PRPH	ENSG00000135406	-0.25182879640999833	[495]	[332,123,NaN]	-2	hSpCas9	negative selection	9546954
49297368	49297391	12	+	27869803	HPAFII	viability after 27 days	GCTCAGGCAGTTGAGAGAGCTGG	PRPH	ENSG00000135406	0.0531113364595624	[210]	[71,150,NaN]	0	hSpCas9	negative selection	9546955
49295475	49295498	12	-	27869803	HPAFII	viability after 15 days	CTGCTTCTCGTTGCTGCGCGTGG	PRPH	ENSG00000135406	0.5096614401729032	[258]	[555,296,NaN]	6	hSpCas9	negative selection	9629399
49296217	49296240	12	+	27869803	HPAFII	viability after 15 days	CAACCTCGTGCTCTTCCGCAAGG	PRPH	ENSG00000135406	-0.4732782212209944	[208]	[146,170,NaN]	-5	hSpCas9	negative selection	9629400
49296455	49296478	12	-	27869803	HPAFII	viability after 15 days	TCTTGCGCTCTAGTTCCAGGCGG	PRPH	ENSG00000135406	-1.947539863853829	[169]	[55,41,NaN]	-9	hSpCas9	negative selection	9629401
49296990	49297013	12	-	27869803	HPAFII	viability after 15 days	CGATGCTCTCGTACTGCGCGCGG	PRPH	ENSG00000135406	-1.1237726966752697	[174]	[163,37,NaN]	-8	hSpCas9	negative selection	9629402
49297234	49297257	12	+	27869803	HPAFII	viability after 15 days	CCAGAGTCTAACGTGCGAGGTGG	PRPH	ENSG00000135406	-0.5128854479661722	[495]	[544,266,NaN]	-5	hSpCas9	negative selection	9629403
49297368	49297391	12	+	27869803	HPAFII	viability after 15 days	GCTCAGGCAGTTGAGAGAGCTGG	PRPH	ENSG00000135406	0.03600247034757825	[210]	[213,243,NaN]	0	hSpCas9	negative selection	9629404
49295475	49295498	12	-	27869803	ASPC1	viability after 36 days	CTGCTTCTCGTTGCTGCGCGTGG	PRPH	ENSG00000135406	0.05781309113894478	[590]	[322,227,125]	0	hSpCas9	negative selection	9711848
49296217	49296240	12	+	27869803	ASPC1	viability after 36 days	CAACCTCGTGCTCTTCCGCAAGG	PRPH	ENSG00000135406	0.4578268230428101	[507]	[198,389,155]	4	hSpCas9	negative selection	9711849
49296455	49296478	12	-	27869803	ASPC1	viability after 36 days	TCTTGCGCTCTAGTTCCAGGCGG	PRPH	ENSG00000135406	-0.24837557827381385	[427]	[250,89,64]	-3	hSpCas9	negative selection	9711850
49296990	49297013	12	-	27869803	ASPC1	viability after 36 days	CGATGCTCTCGTACTGCGCGCGG	PRPH	ENSG00000135406	0.2395516116529972	[443]	[309,192,83]	2	hSpCas9	negative selection	9711851
49297234	49297257	12	+	27869803	ASPC1	viability after 36 days	CCAGAGTCTAACGTGCGAGGTGG	PRPH	ENSG00000135406	0.005103406143303735	[1390]	[969,497,134]	0	hSpCas9	negative selection	9711852
49297368	49297391	12	+	27869803	ASPC1	viability after 36 days	GCTCAGGCAGTTGAGAGAGCTGG	PRPH	ENSG00000135406	-0.29228192923604596	[599]	[182,224,117]	-3	hSpCas9	negative selection	9711853
49295475	49295498	12	-	27869803	PATU8988S	viability after 35 days	CTGCTTCTCGTTGCTGCGCGTGG	PRPH	ENSG00000135406	0.740210645298306	[583]	[345,439,NaN]	7	hSpCas9	negative selection	9794297
49296217	49296240	12	+	27869803	PATU8988S	viability after 35 days	CAACCTCGTGCTCTTCCGCAAGG	PRPH	ENSG00000135406	-0.08484538478628018	[494]	[176,198,NaN]	-1	hSpCas9	negative selection	9794298
49296455	49296478	12	-	27869803	PATU8988S	viability after 35 days	TCTTGCGCTCTAGTTCCAGGCGG	PRPH	ENSG00000135406	0.542775201858046	[374]	[227,211,NaN]	6	hSpCas9	negative selection	9794299
49296990	49297013	12	-	27869803	PATU8988S	viability after 35 days	CGATGCTCTCGTACTGCGCGCGG	PRPH	ENSG00000135406	-0.5070122480418383	[348]	[58,138,NaN]	-5	hSpCas9	negative selection	9794300
49297234	49297257	12	+	27869803	PATU8988S	viability after 35 days	CCAGAGTCTAACGTGCGAGGTGG	PRPH	ENSG00000135406	-0.3197164659653232	[1141]	[375,360,NaN]	-3	hSpCas9	negative selection	9794301
49297368	49297391	12	+	27869803	PATU8988S	viability after 35 days	GCTCAGGCAGTTGAGAGAGCTGG	PRPH	ENSG00000135406	-0.6220078218251525	[505]	[95,168,NaN]	-6	hSpCas9	negative selection	9794302
49295475	49295498	12	-	27869803	PATU8988S	viability after 31 days	CTGCTTCTCGTTGCTGCGCGTGG	PRPH	ENSG00000135406	0.3137061693135206	[583]	[233,359,NaN]	4	hSpCas9	negative selection	9876746
49296217	49296240	12	+	27869803	PATU8988S	viability after 31 days	CAACCTCGTGCTCTTCCGCAAGG	PRPH	ENSG00000135406	-0.15724893907507353	[494]	[154,204,NaN]	-2	hSpCas9	negative selection	9876747
49296455	49296478	12	-	27869803	PATU8988S	viability after 31 days	TCTTGCGCTCTAGTTCCAGGCGG	PRPH	ENSG00000135406	0.39627689470841265	[374]	[176,221,NaN]	5	hSpCas9	negative selection	9876748
49296990	49297013	12	-	27869803	PATU8988S	viability after 31 days	CGATGCTCTCGTACTGCGCGCGG	PRPH	ENSG00000135406	-0.07285529538406965	[348]	[75,203,NaN]	-1	hSpCas9	negative selection	9876749
49297234	49297257	12	+	27869803	PATU8988S	viability after 31 days	CCAGAGTCTAACGTGCGAGGTGG	PRPH	ENSG00000135406	-0.37686728160636995	[1141]	[351,348,NaN]	-4	hSpCas9	negative selection	9876750
49297368	49297391	12	+	27869803	PATU8988S	viability after 31 days	GCTCAGGCAGTTGAGAGAGCTGG	PRPH	ENSG00000135406	-0.4485990121902671	[505]	[164,125,NaN]	-5	hSpCas9	negative selection	9876751
49295475	49295498	12	-	27869803	HPAFII	viability after 35 days	CTGCTTCTCGTTGCTGCGCGTGG	PRPH	ENSG00000135406	0.5488759302673714	[258]	[180,203,NaN]	3	hSpCas9	negative selection	9959195
49296217	49296240	12	+	27869803	HPAFII	viability after 35 days	CAACCTCGTGCTCTTCCGCAAGG	PRPH	ENSG00000135406	0.7396585056217211	[208]	[107,253,NaN]	5	hSpCas9	negative selection	9959196
49296455	49296478	12	-	27869803	HPAFII	viability after 35 days	TCTTGCGCTCTAGTTCCAGGCGG	PRPH	ENSG00000135406	-1.9911257928067994	[169]	[23,18,NaN]	-7	hSpCas9	negative selection	9959197
49296990	49297013	12	-	27869803	HPAFII	viability after 35 days	CGATGCTCTCGTACTGCGCGCGG	PRPH	ENSG00000135406	-1.8182127241814445	[174]	[34,13,NaN]	-7	hSpCas9	negative selection	9959198
49297234	49297257	12	+	27869803	HPAFII	viability after 35 days	CCAGAGTCTAACGTGCGAGGTGG	PRPH	ENSG00000135406	0.3061488547845229	[495]	[404,203,NaN]	2	hSpCas9	negative selection	9959199
49297368	49297391	12	+	27869803	HPAFII	viability after 35 days	GCTCAGGCAGTTGAGAGAGCTGG	PRPH	ENSG00000135406	-0.1884919624379309	[210]	[33,160,NaN]	-1	hSpCas9	negative selection	9959200
49295475	49295498	12	-	27869803	HPAFII	viability after 31 days	CTGCTTCTCGTTGCTGCGCGTGG	PRPH	ENSG00000135406	0.606981231768592	[258]	[229,211,NaN]	4	hSpCas9	negative selection	10041644
49296217	49296240	12	+	27869803	HPAFII	viability after 31 days	CAACCTCGTGCTCTTCCGCAAGG	PRPH	ENSG00000135406	0.46191279464380885	[208]	[106,220,NaN]	3	hSpCas9	negative selection	10041645
49296455	49296478	12	-	27869803	HPAFII	viability after 31 days	TCTTGCGCTCTAGTTCCAGGCGG	PRPH	ENSG00000135406	-2.019677913681056	[169]	[12,34,NaN]	-8	hSpCas9	negative selection	10041646
49296990	49297013	12	-	27869803	HPAFII	viability after 31 days	CGATGCTCTCGTACTGCGCGCGG	PRPH	ENSG00000135406	-1.8652442215015923	[174]	[25,27,NaN]	-8	hSpCas9	negative selection	10041647
49297234	49297257	12	+	27869803	HPAFII	viability after 31 days	CCAGAGTCTAACGTGCGAGGTGG	PRPH	ENSG00000135406	-0.3970422913245065	[495]	[275,140,NaN]	-3	hSpCas9	negative selection	10041648
49297368	49297391	12	+	27869803	HPAFII	viability after 31 days	GCTCAGGCAGTTGAGAGAGCTGG	PRPH	ENSG00000135406	-0.8202552132618662	[210]	[34,101,NaN]	-5	hSpCas9	negative selection	10041649
49295251	49295274	12	-	28162770	P31FUJ	viability	GCGGTGGACCGAAGGTACGGCGG	PRPH	ENSG00000135406	0.40056492826983175	[126]	[196]	4	hSpCas9	negative selection	10217708
49296950	49296973	12	-	28162770	P31FUJ	viability	CGTCAGCTCGGGCTTCACCGTGG	PRPH	ENSG00000135406	0.20187982401073534	[309]	[418]	2	hSpCas9	negative selection	10217709
49297017	49297040	12	+	28162770	P31FUJ	viability	GAAGAACCTGCAGGAGGCGGAGG	PRPH	ENSG00000135406	-0.3869731345421388	[147]	[132]	-3	hSpCas9	negative selection	10217710
49295241	49295264	12	-	28162770	P31FUJ	viability	GAAGGTACGGCGGTATGAGGTGG	PRPH	ENSG00000135406	0.2266294142229185	[175]	[241]	2	hSpCas9	negative selection	10217711
49295292	49295315	12	-	28162770	P31FUJ	viability	GGAGCTGGACGAGTAGGAGAAGG	PRPH	ENSG00000135406	-0.40563880127659413	[61]	[54]	-4	hSpCas9	negative selection	10217712
49295358	49295381	12	-	28162770	P31FUJ	viability	GAAGCTGCCCAGGCGCACCGAGG	PRPH	ENSG00000135406	0.04170498586336385	[166]	[201]	0	hSpCas9	negative selection	10217713
49295420	49295443	12	-	28162770	P31FUJ	viability	GAGAAGTCGAGGCGCTCCGAGGG	PRPH	ENSG00000135406	-0.3197378411856596	[170]	[160]	-3	hSpCas9	negative selection	10217714
49295579	49295602	12	+	28162770	P31FUJ	viability	GGGGAGCTGAGCCAAGCCCGGGG	PRPH	ENSG00000135406	-1.0940959335827865	[217]	[119]	-6	hSpCas9	negative selection	10217715
49296184	49296207	12	+	28162770	P31FUJ	viability	GGAGGAGACGCGCAAGCGGGAGG	PRPH	ENSG00000135406	0.07603589103253994	[154]	[191]	0	hSpCas9	negative selection	10217716
49296933	49296956	12	+	28162770	P31FUJ	viability	GCAGGTGGAGGTGGAAGCCACGG	PRPH	ENSG00000135406	-1.2782126641043248	[354]	[171]	-7	hSpCas9	negative selection	10217717
49295251	49295274	12	-	28162770	TF1	viability	GCGGTGGACCGAAGGTACGGCGG	PRPH	ENSG00000135406	NaN	[NaN]	[73]	1	hSpCas9	negative selection	10387074
49296950	49296973	12	-	28162770	TF1	viability	CGTCAGCTCGGGCTTCACCGTGG	PRPH	ENSG00000135406	NaN	[NaN]	[229]	1	hSpCas9	negative selection	10387075
49297017	49297040	12	+	28162770	TF1	viability	GAAGAACCTGCAGGAGGCGGAGG	PRPH	ENSG00000135406	NaN	[NaN]	[66]	1	hSpCas9	negative selection	10387076
49295241	49295264	12	-	28162770	TF1	viability	GAAGGTACGGCGGTATGAGGTGG	PRPH	ENSG00000135406	NaN	[NaN]	[69]	1	hSpCas9	negative selection	10387077
49295292	49295315	12	-	28162770	TF1	viability	GGAGCTGGACGAGTAGGAGAAGG	PRPH	ENSG00000135406	NaN	[NaN]	[60]	1	hSpCas9	negative selection	10387078
49295358	49295381	12	-	28162770	TF1	viability	GAAGCTGCCCAGGCGCACCGAGG	PRPH	ENSG00000135406	NaN	[NaN]	[109]	1	hSpCas9	negative selection	10387079
49295420	49295443	12	-	28162770	TF1	viability	GAGAAGTCGAGGCGCTCCGAGGG	PRPH	ENSG00000135406	NaN	[NaN]	[82]	1	hSpCas9	negative selection	10387080
49295579	49295602	12	+	28162770	TF1	viability	GGGGAGCTGAGCCAAGCCCGGGG	PRPH	ENSG00000135406	NaN	[NaN]	[70]	1	hSpCas9	negative selection	10387081
49296184	49296207	12	+	28162770	TF1	viability	GGAGGAGACGCGCAAGCGGGAGG	PRPH	ENSG00000135406	NaN	[NaN]	[160]	1	hSpCas9	negative selection	10387082
49296933	49296956	12	+	28162770	TF1	viability	GCAGGTGGAGGTGGAAGCCACGG	PRPH	ENSG00000135406	NaN	[NaN]	[2]	1	hSpCas9	negative selection	10387083
49295251	49295274	12	-	28162770	SKM1	viability	GCGGTGGACCGAAGGTACGGCGG	PRPH	ENSG00000135406	-0.002573943663826239	[33]	[59]	0	hSpCas9	negative selection	10556440
49296950	49296973	12	-	28162770	SKM1	viability	CGTCAGCTCGGGCTTCACCGTGG	PRPH	ENSG00000135406	0.2668075689358505	[62]	[133]	2	hSpCas9	negative selection	10556441
49297017	49297040	12	+	28162770	SKM1	viability	GAAGAACCTGCAGGAGGCGGAGG	PRPH	ENSG00000135406	0.032800386438058826	[46]	[84]	0	hSpCas9	negative selection	10556442
49295241	49295264	12	-	28162770	SKM1	viability	GAAGGTACGGCGGTATGAGGTGG	PRPH	ENSG00000135406	-0.4234523215317306	[43]	[57]	-3	hSpCas9	negative selection	10556443
49295292	49295315	12	-	28162770	SKM1	viability	GGAGCTGGACGAGTAGGAGAAGG	PRPH	ENSG00000135406	-2.262574289407987	[18]	[6]	-8	hSpCas9	negative selection	10556444
49295358	49295381	12	-	28162770	SKM1	viability	GAAGCTGCCCAGGCGCACCGAGG	PRPH	ENSG00000135406	-0.3365748708517637	[54]	[76]	-3	hSpCas9	negative selection	10556445
49295420	49295443	12	-	28162770	SKM1	viability	GAGAAGTCGAGGCGCTCCGAGGG	PRPH	ENSG00000135406	0.4675049191729794	[44]	[109]	4	hSpCas9	negative selection	10556446
49295579	49295602	12	+	28162770	SKM1	viability	GGGGAGCTGAGCCAAGCCCGGGG	PRPH	ENSG00000135406	-0.2556548754681964	[51]	[76]	-2	hSpCas9	negative selection	10556447
49296184	49296207	12	+	28162770	SKM1	viability	GGAGGAGACGCGCAAGCGGGAGG	PRPH	ENSG00000135406	1.2543491881081095	[22]	[96]	9	hSpCas9	negative selection	10556448
49296933	49296956	12	+	28162770	SKM1	viability	GCAGGTGGAGGTGGAAGCCACGG	PRPH	ENSG00000135406	-1.0541751401510389	[73]	[62]	-6	hSpCas9	negative selection	10556449
49295251	49295274	12	-	28162770	SKM1	viability	GCGGTGGACCGAAGGTACGGCGG	PRPH	ENSG00000135406	-0.002573943663826239	[33]	[59]	0	hSpCas9	negative selection	10725806
49296950	49296973	12	-	28162770	SKM1	viability	CGTCAGCTCGGGCTTCACCGTGG	PRPH	ENSG00000135406	0.2668075689358505	[62]	[133]	2	hSpCas9	negative selection	10725807
49297017	49297040	12	+	28162770	SKM1	viability	GAAGAACCTGCAGGAGGCGGAGG	PRPH	ENSG00000135406	0.032800386438058826	[46]	[84]	0	hSpCas9	negative selection	10725808
49295241	49295264	12	-	28162770	SKM1	viability	GAAGGTACGGCGGTATGAGGTGG	PRPH	ENSG00000135406	-0.4234523215317306	[43]	[57]	-3	hSpCas9	negative selection	10725809
49295292	49295315	12	-	28162770	SKM1	viability	GGAGCTGGACGAGTAGGAGAAGG	PRPH	ENSG00000135406	-2.262574289407987	[18]	[6]	-8	hSpCas9	negative selection	10725810
49295358	49295381	12	-	28162770	SKM1	viability	GAAGCTGCCCAGGCGCACCGAGG	PRPH	ENSG00000135406	-0.3365748708517637	[54]	[76]	-3	hSpCas9	negative selection	10725811
49295420	49295443	12	-	28162770	SKM1	viability	GAGAAGTCGAGGCGCTCCGAGGG	PRPH	ENSG00000135406	0.4675049191729794	[44]	[109]	4	hSpCas9	negative selection	10725812
49295579	49295602	12	+	28162770	SKM1	viability	GGGGAGCTGAGCCAAGCCCGGGG	PRPH	ENSG00000135406	-0.2556548754681964	[51]	[76]	-2	hSpCas9	negative selection	10725813
49296184	49296207	12	+	28162770	SKM1	viability	GGAGGAGACGCGCAAGCGGGAGG	PRPH	ENSG00000135406	1.2543491881081095	[22]	[96]	9	hSpCas9	negative selection	10725814
49296933	49296956	12	+	28162770	SKM1	viability	GCAGGTGGAGGTGGAAGCCACGG	PRPH	ENSG00000135406	-1.0541751401510389	[73]	[62]	-6	hSpCas9	negative selection	10725815
49295251	49295274	12	-	28162770	PL21	viability	GCGGTGGACCGAAGGTACGGCGG	PRPH	ENSG00000135406	0.41354325259851343	[68]	[39]	3	hSpCas9	negative selection	10895172
49296950	49296973	12	-	28162770	PL21	viability	CGTCAGCTCGGGCTTCACCGTGG	PRPH	ENSG00000135406	0.22216592081931905	[194]	[98]	2	hSpCas9	negative selection	10895173
49297017	49297040	12	+	28162770	PL21	viability	GAAGAACCTGCAGGAGGCGGAGG	PRPH	ENSG00000135406	-0.4458523196293956	[168]	[53]	-3	hSpCas9	negative selection	10895174
49295241	49295264	12	-	28162770	PL21	viability	GAAGGTACGGCGGTATGAGGTGG	PRPH	ENSG00000135406	0.39526995582131047	[144]	[82]	3	hSpCas9	negative selection	10895175
49295292	49295315	12	-	28162770	PL21	viability	GGAGCTGGACGAGTAGGAGAAGG	PRPH	ENSG00000135406	1.3791097555346397	[52]	[59]	9	hSpCas9	negative selection	10895176
49295358	49295381	12	-	28162770	PL21	viability	GAAGCTGCCCAGGCGCACCGAGG	PRPH	ENSG00000135406	0.9226056389604114	[119]	[98]	7	hSpCas9	negative selection	10895177
49295420	49295443	12	-	28162770	PL21	viability	GAGAAGTCGAGGCGCTCCGAGGG	PRPH	ENSG00000135406	-0.4361697662320562	[142]	[45]	-3	hSpCas9	negative selection	10895178
49295579	49295602	12	+	28162770	PL21	viability	GGGGAGCTGAGCCAAGCCCGGGG	PRPH	ENSG00000135406	-0.6979807714914663	[163]	[43]	-5	hSpCas9	negative selection	10895179
49296184	49296207	12	+	28162770	PL21	viability	GGAGGAGACGCGCAAGCGGGAGG	PRPH	ENSG00000135406	0.42755011059239245	[81]	[47]	4	hSpCas9	negative selection	10895180
49296933	49296956	12	+	28162770	PL21	viability	GCAGGTGGAGGTGGAAGCCACGG	PRPH	ENSG00000135406	-0.4519370820903731	[241]	[76]	-3	hSpCas9	negative selection	10895181
49295251	49295274	12	-	28162770	P31FUJ	viability	GCGGTGGACCGAAGGTACGGCGG	PRPH	ENSG00000135406	0.40056492826983175	[126]	[196]	4	hSpCas9	negative selection	11064538
49296950	49296973	12	-	28162770	P31FUJ	viability	CGTCAGCTCGGGCTTCACCGTGG	PRPH	ENSG00000135406	0.20187982401073534	[309]	[418]	2	hSpCas9	negative selection	11064539
49297017	49297040	12	+	28162770	P31FUJ	viability	GAAGAACCTGCAGGAGGCGGAGG	PRPH	ENSG00000135406	-0.3869731345421388	[147]	[132]	-3	hSpCas9	negative selection	11064540
49295241	49295264	12	-	28162770	P31FUJ	viability	GAAGGTACGGCGGTATGAGGTGG	PRPH	ENSG00000135406	0.2266294142229185	[175]	[241]	2	hSpCas9	negative selection	11064541
49295292	49295315	12	-	28162770	P31FUJ	viability	GGAGCTGGACGAGTAGGAGAAGG	PRPH	ENSG00000135406	-0.40563880127659413	[61]	[54]	-4	hSpCas9	negative selection	11064542
49295358	49295381	12	-	28162770	P31FUJ	viability	GAAGCTGCCCAGGCGCACCGAGG	PRPH	ENSG00000135406	0.04170498586336385	[166]	[201]	0	hSpCas9	negative selection	11064543
49295420	49295443	12	-	28162770	P31FUJ	viability	GAGAAGTCGAGGCGCTCCGAGGG	PRPH	ENSG00000135406	-0.3197378411856596	[170]	[160]	-3	hSpCas9	negative selection	11064544
49295579	49295602	12	+	28162770	P31FUJ	viability	GGGGAGCTGAGCCAAGCCCGGGG	PRPH	ENSG00000135406	-1.0940959335827865	[217]	[119]	-6	hSpCas9	negative selection	11064545
49296184	49296207	12	+	28162770	P31FUJ	viability	GGAGGAGACGCGCAAGCGGGAGG	PRPH	ENSG00000135406	0.07603589103253994	[154]	[191]	0	hSpCas9	negative selection	11064546
49296933	49296956	12	+	28162770	P31FUJ	viability	GCAGGTGGAGGTGGAAGCCACGG	PRPH	ENSG00000135406	-1.2782126641043248	[354]	[171]	-7	hSpCas9	negative selection	11064547
49295251	49295274	12	-	28162770	OCIAML5	viability	GCGGTGGACCGAAGGTACGGCGG	PRPH	ENSG00000135406	0.2537280931585997	[45]	[98]	2	hSpCas9	negative selection	11233904
49296950	49296973	12	-	28162770	OCIAML5	viability	CGTCAGCTCGGGCTTCACCGTGG	PRPH	ENSG00000135406	1.0850021734095463	[122]	[470]	8	hSpCas9	negative selection	11233905
49297017	49297040	12	+	28162770	OCIAML5	viability	GAAGAACCTGCAGGAGGCGGAGG	PRPH	ENSG00000135406	-1.4275687423360868	[151]	[101]	-7	hSpCas9	negative selection	11233906
49295241	49295264	12	-	28162770	OCIAML5	viability	GAAGGTACGGCGGTATGAGGTGG	PRPH	ENSG00000135406	0.16679245638731904	[75]	[153]	1	hSpCas9	negative selection	11233907
49295292	49295315	12	-	28162770	OCIAML5	viability	GGAGCTGGACGAGTAGGAGAAGG	PRPH	ENSG00000135406	-0.0009299567784795126	[50]	[91]	0	hSpCas9	negative selection	11233908
49295358	49295381	12	-	28162770	OCIAML5	viability	GAAGCTGCCCAGGCGCACCGAGG	PRPH	ENSG00000135406	-0.004069664309046983	[34]	[62]	0	hSpCas9	negative selection	11233909
49295420	49295443	12	-	28162770	OCIAML5	viability	GAGAAGTCGAGGCGCTCCGAGGG	PRPH	ENSG00000135406	-0.2052987856693691	[98]	[154]	-1	hSpCas9	negative selection	11233910
49295579	49295602	12	+	28162770	OCIAML5	viability	GGGGAGCTGAGCCAAGCCCGGGG	PRPH	ENSG00000135406	-2.729384051089168	[168]	[45]	-8	hSpCas9	negative selection	11233911
49296184	49296207	12	+	28162770	OCIAML5	viability	GGAGGAGACGCGCAAGCGGGAGG	PRPH	ENSG00000135406	-0.17964122889250145	[63]	[101]	-1	hSpCas9	negative selection	11233912
49296933	49296956	12	+	28162770	OCIAML5	viability	GCAGGTGGAGGTGGAAGCCACGG	PRPH	ENSG00000135406	-3.1675683965919266	[223]	[44]	-9	hSpCas9	negative selection	11233913
49295251	49295274	12	-	28162770	EOL1	viability	GCGGTGGACCGAAGGTACGGCGG	PRPH	ENSG00000135406	0.07369121087634378	[201]	[111]	0	hSpCas9	negative selection	11403270
49296950	49296973	12	-	28162770	EOL1	viability	CGTCAGCTCGGGCTTCACCGTGG	PRPH	ENSG00000135406	1.086949814297837	[234]	[262]	8	hSpCas9	negative selection	11403271
49297017	49297040	12	+	28162770	EOL1	viability	GAAGAACCTGCAGGAGGCGGAGG	PRPH	ENSG00000135406	0.6001556367316911	[292]	[233]	5	hSpCas9	negative selection	11403272
49295241	49295264	12	-	28162770	EOL1	viability	GAAGGTACGGCGGTATGAGGTGG	PRPH	ENSG00000135406	-0.29148915472608977	[301]	[129]	-2	hSpCas9	negative selection	11403273
49295292	49295315	12	-	28162770	EOL1	viability	GGAGCTGGACGAGTAGGAGAAGG	PRPH	ENSG00000135406	0.14213920664316104	[85]	[49]	1	hSpCas9	negative selection	11403274
49295358	49295381	12	-	28162770	EOL1	viability	GAAGCTGCCCAGGCGCACCGAGG	PRPH	ENSG00000135406	-0.3564723797366219	[225]	[92]	-3	hSpCas9	negative selection	11403275
49295420	49295443	12	-	28162770	EOL1	viability	GAGAAGTCGAGGCGCTCCGAGGG	PRPH	ENSG00000135406	0.5744490039920114	[180]	[141]	5	hSpCas9	negative selection	11403276
49295579	49295602	12	+	28162770	EOL1	viability	GGGGAGCTGAGCCAAGCCCGGGG	PRPH	ENSG00000135406	0.6202137366979104	[162]	[131]	5	hSpCas9	negative selection	11403277
49296184	49296207	12	+	28162770	EOL1	viability	GGAGGAGACGCGCAAGCGGGAGG	PRPH	ENSG00000135406	0.04841942973270308	[144]	[78]	0	hSpCas9	negative selection	11403278
49296933	49296956	12	+	28162770	EOL1	viability	GCAGGTGGAGGTGGAAGCCACGG	PRPH	ENSG00000135406	-1.922335514673707	[258]	[35]	-8	hSpCas9	negative selection	11403279
49295251	49295274	12	-	28162770	MOLM13	viability	GCGGTGGACCGAAGGTACGGCGG	PRPH	ENSG00000135406	1.5295284473369646	[125]	[262]	9	hSpCas9	negative selection	11572636
49296950	49296973	12	-	28162770	MOLM13	viability	CGTCAGCTCGGGCTTCACCGTGG	PRPH	ENSG00000135406	0.20957738595318817	[304]	[254]	1	hSpCas9	negative selection	11572637
49297017	49297040	12	+	28162770	MOLM13	viability	GAAGAACCTGCAGGAGGCGGAGG	PRPH	ENSG00000135406	-0.06782960015672834	[215]	[148]	0	hSpCas9	negative selection	11572638
49295241	49295264	12	-	28162770	MOLM13	viability	GAAGGTACGGCGGTATGAGGTGG	PRPH	ENSG00000135406	0.2185299126078616	[251]	[211]	1	hSpCas9	negative selection	11572639
49295292	49295315	12	-	28162770	MOLM13	viability	GGAGCTGGACGAGTAGGAGAAGG	PRPH	ENSG00000135406	-1.1745586138373374	[127]	[40]	-6	hSpCas9	negative selection	11572640
49295358	49295381	12	-	28162770	MOLM13	viability	GAAGCTGCCCAGGCGCACCGAGG	PRPH	ENSG00000135406	0.25504073287900175	[225]	[194]	1	hSpCas9	negative selection	11572641
49295420	49295443	12	-	28162770	MOLM13	viability	GAGAAGTCGAGGCGCTCCGAGGG	PRPH	ENSG00000135406	-0.11707311917657748	[236]	[157]	0	hSpCas9	negative selection	11572642
49295579	49295602	12	+	28162770	MOLM13	viability	GGGGAGCTGAGCCAAGCCCGGGG	PRPH	ENSG00000135406	-0.8150445817269197	[145]	[59]	-4	hSpCas9	negative selection	11572643
49296184	49296207	12	+	28162770	MOLM13	viability	GGAGGAGACGCGCAAGCGGGAGG	PRPH	ENSG00000135406	-0.8584709596580442	[162]	[64]	-5	hSpCas9	negative selection	11572644
49296933	49296956	12	+	28162770	MOLM13	viability	GCAGGTGGAGGTGGAAGCCACGG	PRPH	ENSG00000135406	-2.7308904825699187	[403]	[43]	-8	hSpCas9	negative selection	11572645
49295251	49295274	12	-	28162770	HEL	viability	GCGGTGGACCGAAGGTACGGCGG	PRPH	ENSG00000135406	-0.6251943732462761	[117]	[48]	-4	hSpCas9	negative selection	11742002
49296950	49296973	12	-	28162770	HEL	viability	CGTCAGCTCGGGCTTCACCGTGG	PRPH	ENSG00000135406	-0.614271786205667	[238]	[99]	-4	hSpCas9	negative selection	11742003
49297017	49297040	12	+	28162770	HEL	viability	GAAGAACCTGCAGGAGGCGGAGG	PRPH	ENSG00000135406	-0.8131437195558695	[202]	[73]	-5	hSpCas9	negative selection	11742004
49295241	49295264	12	-	28162770	HEL	viability	GAAGGTACGGCGGTATGAGGTGG	PRPH	ENSG00000135406	-0.268256161940898	[219]	[116]	-2	hSpCas9	negative selection	11742005
49295292	49295315	12	-	28162770	HEL	viability	GGAGCTGGACGAGTAGGAGAAGG	PRPH	ENSG00000135406	-2.1227959143626203	[67]	[9]	-8	hSpCas9	negative selection	11742006
49295358	49295381	12	-	28162770	HEL	viability	GAAGCTGCCCAGGCGCACCGAGG	PRPH	ENSG00000135406	1.3951138654889674	[148]	[250]	9	hSpCas9	negative selection	11742007
49295420	49295443	12	-	28162770	HEL	viability	GAGAAGTCGAGGCGCTCCGAGGG	PRPH	ENSG00000135406	-0.06846366610076754	[184]	[112]	0	hSpCas9	negative selection	11742008
49295579	49295602	12	+	28162770	HEL	viability	GGGGAGCTGAGCCAAGCCCGGGG	PRPH	ENSG00000135406	-0.9422236687207991	[140]	[46]	-5	hSpCas9	negative selection	11742009
49296184	49296207	12	+	28162770	HEL	viability	GGAGGAGACGCGCAAGCGGGAGG	PRPH	ENSG00000135406	0.9753141710872278	[107]	[135]	8	hSpCas9	negative selection	11742010
49296933	49296956	12	+	28162770	HEL	viability	GCAGGTGGAGGTGGAAGCCACGG	PRPH	ENSG00000135406	-2.2467846316380733	[288]	[38]	-8	hSpCas9	negative selection	11742011
49295251	49295274	12	-	28162770	MV411	viability	GCGGTGGACCGAAGGTACGGCGG	PRPH	ENSG00000135406	0.2474375507827754	[94]	[94]	2	hSpCas9	negative selection	11911368
49296950	49296973	12	-	28162770	MV411	viability	CGTCAGCTCGGGCTTCACCGTGG	PRPH	ENSG00000135406	0.15780033829809875	[165]	[155]	1	hSpCas9	negative selection	11911369
49297017	49297040	12	+	28162770	MV411	viability	GAAGAACCTGCAGGAGGCGGAGG	PRPH	ENSG00000135406	-0.2444155455468994	[179]	[127]	-2	hSpCas9	negative selection	11911370
49295241	49295264	12	-	28162770	MV411	viability	GAAGGTACGGCGGTATGAGGTGG	PRPH	ENSG00000135406	0.005731654389493256	[187]	[158]	0	hSpCas9	negative selection	11911371
49295292	49295315	12	-	28162770	MV411	viability	GGAGCTGGACGAGTAGGAGAAGG	PRPH	ENSG00000135406	-0.9541963103868754	[68]	[29]	-6	hSpCas9	negative selection	11911372
49295358	49295381	12	-	28162770	MV411	viability	GAAGCTGCCCAGGCGCACCGAGG	PRPH	ENSG00000135406	0.7122786059822329	[120]	[166]	6	hSpCas9	negative selection	11911373
49295420	49295443	12	-	28162770	MV411	viability	GAGAAGTCGAGGCGCTCCGAGGG	PRPH	ENSG00000135406	-0.24851994387963589	[164]	[116]	-2	hSpCas9	negative selection	11911374
49295579	49295602	12	+	28162770	MV411	viability	GGGGAGCTGAGCCAAGCCCGGGG	PRPH	ENSG00000135406	-0.20960747501764387	[150]	[109]	-2	hSpCas9	negative selection	11911375
49296184	49296207	12	+	28162770	MV411	viability	GGAGGAGACGCGCAAGCGGGAGG	PRPH	ENSG00000135406	0.48690348547816453	[71]	[84]	4	hSpCas9	negative selection	11911376
49296933	49296956	12	+	28162770	MV411	viability	GCAGGTGGAGGTGGAAGCCACGG	PRPH	ENSG00000135406	-1.128071584309431	[191]	[73]	-6	hSpCas9	negative selection	11911377
49295251	49295274	12	-	28162770	MONOMAC1	viability	GCGGTGGACCGAAGGTACGGCGG	PRPH	ENSG00000135406	-0.9132438810589627	[68]	[41]	-6	hSpCas9	negative selection	12080734
49296950	49296973	12	-	28162770	MONOMAC1	viability	CGTCAGCTCGGGCTTCACCGTGG	PRPH	ENSG00000135406	0.6285674474529079	[100]	[178]	6	hSpCas9	negative selection	12080735
49297017	49297040	12	+	28162770	MONOMAC1	viability	GAAGAACCTGCAGGAGGCGGAGG	PRPH	ENSG00000135406	-1.4079336295581724	[124]	[53]	-8	hSpCas9	negative selection	12080736
49295241	49295264	12	-	28162770	MONOMAC1	viability	GAAGGTACGGCGGTATGAGGTGG	PRPH	ENSG00000135406	-0.20952779124275067	[115]	[114]	-2	hSpCas9	negative selection	12080737
49295292	49295315	12	-	28162770	MONOMAC1	viability	GGAGCTGGACGAGTAGGAGAAGG	PRPH	ENSG00000135406	-1.6824636742297956	[41]	[14]	-8	hSpCas9	negative selection	12080738
49295358	49295381	12	-	28162770	MONOMAC1	viability	GAAGCTGCCCAGGCGCACCGAGG	PRPH	ENSG00000135406	0.1907791834842659	[106]	[139]	2	hSpCas9	negative selection	12080739
49295420	49295443	12	-	28162770	MONOMAC1	viability	GAGAAGTCGAGGCGCTCCGAGGG	PRPH	ENSG00000135406	0.11534747515693777	[90]	[112]	1	hSpCas9	negative selection	12080740
49295579	49295602	12	+	28162770	MONOMAC1	viability	GGGGAGCTGAGCCAAGCCCGGGG	PRPH	ENSG00000135406	0.09541404675097481	[88]	[108]	1	hSpCas9	negative selection	12080741
49296184	49296207	12	+	28162770	MONOMAC1	viability	GGAGGAGACGCGCAAGCGGGAGG	PRPH	ENSG00000135406	0.5048818000074518	[74]	[121]	5	hSpCas9	negative selection	12080742
49296933	49296956	12	+	28162770	MONOMAC1	viability	GCAGGTGGAGGTGGAAGCCACGG	PRPH	ENSG00000135406	-0.28130576395715745	[140]	[132]	-2	hSpCas9	negative selection	12080743
49295251	49295274	12	-	28162770	OCIAML2	viability	GCGGTGGACCGAAGGTACGGCGG	PRPH	ENSG00000135406	-1.1487017303547986	[15]	[39]	-6	hSpCas9	negative selection	12250100
49296950	49296973	12	-	28162770	OCIAML2	viability	CGTCAGCTCGGGCTTCACCGTGG	PRPH	ENSG00000135406	0.8560992559090224	[29]	[300]	8	hSpCas9	negative selection	12250101
49297017	49297040	12	+	28162770	OCIAML2	viability	GAAGAACCTGCAGGAGGCGGAGG	PRPH	ENSG00000135406	-0.49265613157216015	[32]	[129]	-4	hSpCas9	negative selection	12250102
49295241	49295264	12	-	28162770	OCIAML2	viability	GAAGGTACGGCGGTATGAGGTGG	PRPH	ENSG00000135406	0.11433267547899513	[37]	[227]	1	hSpCas9	negative selection	12250103
49295292	49295315	12	-	28162770	OCIAML2	viability	GGAGCTGGACGAGTAGGAGAAGG	PRPH	ENSG00000135406	0.4038392926739798	[11]	[87]	4	hSpCas9	negative selection	12250104
49295358	49295381	12	-	28162770	OCIAML2	viability	GAAGCTGCCCAGGCGCACCGAGG	PRPH	ENSG00000135406	0.2692182774571663	[24]	[166]	2	hSpCas9	negative selection	12250105
49295420	49295443	12	-	28162770	OCIAML2	viability	GAGAAGTCGAGGCGCTCCGAGGG	PRPH	ENSG00000135406	-1.2296217257383664	[32]	[77]	-7	hSpCas9	negative selection	12250106
49295579	49295602	12	+	28162770	OCIAML2	viability	GGGGAGCTGAGCCAAGCCCGGGG	PRPH	ENSG00000135406	0.2663357689240451	[17]	[119]	2	hSpCas9	negative selection	12250107
49296184	49296207	12	+	28162770	OCIAML2	viability	GGAGGAGACGCGCAAGCGGGAGG	PRPH	ENSG00000135406	0.9508339431961155	[13]	[149]	8	hSpCas9	negative selection	12250108
49296933	49296956	12	+	28162770	OCIAML2	viability	GCAGGTGGAGGTGGAAGCCACGG	PRPH	ENSG00000135406	-2.8409982751872764	[52]	[40]	-9	hSpCas9	negative selection	12250109
49295251	49295274	12	-	28162770	OCIAML3	viability	GCGGTGGACCGAAGGTACGGCGG	PRPH	ENSG00000135406	0.4486366970843305	[24]	[102]	4	hSpCas9	negative selection	12419466
49296950	49296973	12	-	28162770	OCIAML3	viability	CGTCAGCTCGGGCTTCACCGTGG	PRPH	ENSG00000135406	0.1687419796122758	[60]	[206]	1	hSpCas9	negative selection	12419467
49297017	49297040	12	+	28162770	OCIAML3	viability	GAAGAACCTGCAGGAGGCGGAGG	PRPH	ENSG00000135406	-2.043315041687753	[70]	[51]	-8	hSpCas9	negative selection	12419468
49295241	49295264	12	-	28162770	OCIAML3	viability	GAAGGTACGGCGGTATGAGGTGG	PRPH	ENSG00000135406	-0.3969707932646095	[40]	[93]	-3	hSpCas9	negative selection	12419469
49295292	49295315	12	-	28162770	OCIAML3	viability	GGAGCTGGACGAGTAGGAGAAGG	PRPH	ENSG00000135406	0.5214695770957731	[8]	[38]	5	hSpCas9	negative selection	12419470
49295358	49295381	12	-	28162770	OCIAML3	viability	GAAGCTGCCCAGGCGCACCGAGG	PRPH	ENSG00000135406	-0.26719732405705454	[58]	[147]	-2	hSpCas9	negative selection	12419471
49295420	49295443	12	-	28162770	OCIAML3	viability	GAGAAGTCGAGGCGCTCCGAGGG	PRPH	ENSG00000135406	0.10448380602740731	[56]	[184]	1	hSpCas9	negative selection	12419472
49295579	49295602	12	+	28162770	OCIAML3	viability	GGGGAGCTGAGCCAAGCCCGGGG	PRPH	ENSG00000135406	-0.37558412119066087	[51]	[120]	-3	hSpCas9	negative selection	12419473
49296184	49296207	12	+	28162770	OCIAML3	viability	GGAGGAGACGCGCAAGCGGGAGG	PRPH	ENSG00000135406	1.4391592236110364	[42]	[351]	9	hSpCas9	negative selection	12419474
49296933	49296956	12	+	28162770	OCIAML3	viability	GCAGGTGGAGGTGGAAGCCACGG	PRPH	ENSG00000135406	-1.1543080868110502	[86]	[117]	-7	hSpCas9	negative selection	12419475