Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:283659
• Symbol:PRTG
• Description:protogenin

DataSource: http://genomecrispr.dkfz.de/#!/results/PRTG

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
55641154	55641177	15	-	26472758	Jiyoye	viability	GCTTACAACAACATAGACGATGG	PRTG	ENSG00000166450	-0.9059825037537568	[81]	[32]	-6	hSpCas9	negative selection	129249
55672582	55672605	15	+	26472758	Jiyoye	viability	GAAATGGTGGTACAGTTCAGAGG	PRTG	ENSG00000166450	-0.8128324193853694	[402]	[172]	-5	hSpCas9	negative selection	129250
55639655	55639678	15	+	26472758	Jiyoye	viability	GAACCAAAGAAGCATTCTGCAGG	PRTG	ENSG00000166450	-0.405454482592405	[136]	[77]	-3	hSpCas9	negative selection	129251
55628973	55628996	15	+	26472758	Jiyoye	viability	CAAGTTTTCTAGCAAAGCCATGG	PRTG	ENSG00000166450	0.36870123369123764	[37]	[36]	2	hSpCas9	negative selection	129252
55628876	55628899	15	-	26472758	Jiyoye	viability	GGAGCTGGCAGTACTTCCAAAGG	PRTG	ENSG00000166450	-0.06607673171826606	[117]	[84]	0	hSpCas9	negative selection	129253
55742856	55742879	15	+	26472758	Jiyoye	viability	GCAGCAGGAGCAGGAGCGCGCGG	PRTG	ENSG00000166450	-0.46481700611805504	[96]	[52]	-3	hSpCas9	negative selection	129254
55742825	55742848	15	+	26472758	Jiyoye	viability	AAAGCGCGCCCACCTGGCAAAGG	PRTG	ENSG00000166450	0.23267765027373688	[157]	[139]	1	hSpCas9	negative selection	129255
55679307	55679330	15	-	26472758	Jiyoye	viability	GGAAGGAAGATACATTCGAATGG	PRTG	ENSG00000166450	0.3904966403592431	[86]	[85]	3	hSpCas9	negative selection	129256
55677973	55677996	15	-	26472758	Jiyoye	viability	TGCATGGCTGAGAATAGCCAAGG	PRTG	ENSG00000166450	1.3926758118107583	[49]	[98]	8	hSpCas9	negative selection	129257
55641154	55641177	15	-	26472758	KBM7	viability	GCTTACAACAACATAGACGATGG	PRTG	ENSG00000166450	0.28589299935428414	[285,316]	[106,234]	3	hSpCas9	negative selection	320367
55672582	55672605	15	+	26472758	KBM7	viability	GAAATGGTGGTACAGTTCAGAGG	PRTG	ENSG00000166450	0.9069763066773369	[1661,1788]	[1620,1456]	8	hSpCas9	negative selection	320368
55639655	55639678	15	+	26472758	KBM7	viability	GAACCAAAGAAGCATTCTGCAGG	PRTG	ENSG00000166450	0.15690646554607732	[589,504]	[179,380]	1	hSpCas9	negative selection	320369
55628973	55628996	15	+	26472758	KBM7	viability	CAAGTTTTCTAGCAAAGCCATGG	PRTG	ENSG00000166450	1.5723219408355966	[97,66]	[175,57]	9	hSpCas9	negative selection	320370
55628876	55628899	15	-	26472758	KBM7	viability	GGAGCTGGCAGTACTTCCAAAGG	PRTG	ENSG00000166450	-0.09547814446305547	[327,184]	[143,79]	-1	hSpCas9	negative selection	320371
55742856	55742879	15	+	26472758	KBM7	viability	GCAGCAGGAGCAGGAGCGCGCGG	PRTG	ENSG00000166450	-1.0905645112093347	[580,398]	[131,83]	-7	hSpCas9	negative selection	320372
55742825	55742848	15	+	26472758	KBM7	viability	AAAGCGCGCCCACCTGGCAAAGG	PRTG	ENSG00000166450	0.22060666382469618	[612,561]	[368,279]	2	hSpCas9	negative selection	320373
55679307	55679330	15	-	26472758	KBM7	viability	GGAAGGAAGATACATTCGAATGG	PRTG	ENSG00000166450	-0.2409839239225623	[616,511]	[250,198]	-2	hSpCas9	negative selection	320374
55677973	55677996	15	-	26472758	KBM7	viability	TGCATGGCTGAGAATAGCCAAGG	PRTG	ENSG00000166450	0.5832935900585031	[634,754]	[414,568]	6	hSpCas9	negative selection	320375
55641154	55641177	15	-	26472758	Raji	viability	GCTTACAACAACATAGACGATGG	PRTG	ENSG00000166450	0.56485630097284	[133]	[45]	5	hSpCas9	negative selection	511485
55672582	55672605	15	+	26472758	Raji	viability	GAAATGGTGGTACAGTTCAGAGG	PRTG	ENSG00000166450	0.5719810837651875	[886]	[305]	5	hSpCas9	negative selection	511486
55639655	55639678	15	+	26472758	Raji	viability	GAACCAAAGAAGCATTCTGCAGG	PRTG	ENSG00000166450	0.03367384919059002	[260]	[61]	0	hSpCas9	negative selection	511487
55628973	55628996	15	+	26472758	Raji	viability	CAAGTTTTCTAGCAAAGCCATGG	PRTG	ENSG00000166450	-0.7670855825425416	[43]	[5]	-5	hSpCas9	negative selection	511488
55628876	55628899	15	-	26472758	Raji	viability	GGAGCTGGCAGTACTTCCAAAGG	PRTG	ENSG00000166450	-0.14559720579627144	[142]	[29]	-1	hSpCas9	negative selection	511489
55742856	55742879	15	+	26472758	Raji	viability	GCAGCAGGAGCAGGAGCGCGCGG	PRTG	ENSG00000166450	-1.877509572236192	[189]	[11]	-8	hSpCas9	negative selection	511490
55742825	55742848	15	+	26472758	Raji	viability	AAAGCGCGCCCACCTGGCAAAGG	PRTG	ENSG00000166450	-0.006572653923485994	[315]	[72]	0	hSpCas9	negative selection	511491
55679307	55679330	15	-	26472758	Raji	viability	GGAAGGAAGATACATTCGAATGG	PRTG	ENSG00000166450	-0.7204354892437201	[283]	[39]	-5	hSpCas9	negative selection	511492
55677973	55677996	15	-	26472758	Raji	viability	TGCATGGCTGAGAATAGCCAAGG	PRTG	ENSG00000166450	0.6093566714237241	[321]	[113]	6	hSpCas9	negative selection	511493
55641154	55641177	15	-	26472758	K562	viability	GCTTACAACAACATAGACGATGG	PRTG	ENSG00000166450	1.3014496727028257	[185]	[386]	9	hSpCas9	negative selection	702603
55672582	55672605	15	+	26472758	K562	viability	GAAATGGTGGTACAGTTCAGAGG	PRTG	ENSG00000166450	0.8395621092273406	[1364]	[2061]	7	hSpCas9	negative selection	702604
55639655	55639678	15	+	26472758	K562	viability	GAACCAAAGAAGCATTCTGCAGG	PRTG	ENSG00000166450	0.4576340120915956	[382]	[443]	3	hSpCas9	negative selection	702605
55628973	55628996	15	+	26472758	K562	viability	CAAGTTTTCTAGCAAAGCCATGG	PRTG	ENSG00000166450	0.4260255341563943	[81]	[92]	3	hSpCas9	negative selection	702606
55628876	55628899	15	-	26472758	K562	viability	GGAGCTGGCAGTACTTCCAAAGG	PRTG	ENSG00000166450	-0.11815135171826141	[251]	[195]	-1	hSpCas9	negative selection	702607
55742856	55742879	15	+	26472758	K562	viability	GCAGCAGGAGCAGGAGCGCGCGG	PRTG	ENSG00000166450	-1.7735031803308152	[323]	[79]	-7	hSpCas9	negative selection	702608
55742825	55742848	15	+	26472758	K562	viability	AAAGCGCGCCCACCTGGCAAAGG	PRTG	ENSG00000166450	0.2905671884703365	[522]	[539]	2	hSpCas9	negative selection	702609
55679307	55679330	15	-	26472758	K562	viability	GGAAGGAAGATACATTCGAATGG	PRTG	ENSG00000166450	1.3608128151781826	[362]	[786]	9	hSpCas9	negative selection	702610
55677973	55677996	15	-	26472758	K562	viability	TGCATGGCTGAGAATAGCCAAGG	PRTG	ENSG00000166450	0.34276650897990024	[566]	[606]	2	hSpCas9	negative selection	702611
55673594	55673617	15	+	26627737	DLD1	viability	TTTGGCTGGGATTGGCAGCCAGG	PRTG	ENSG00000166450	0.18232124393455873	[309]	[57,150,120]	1	hSpCas9	negative selection	791070
55677870	55677893	15	+	26627737	DLD1	viability	AAGAATGGCTGAGCTTGACATGG	PRTG	ENSG00000166450	-0.0753113207745062	[586]	[256,269,22]	-1	hSpCas9	negative selection	791071
55680082	55680105	15	+	26627737	DLD1	viability	TGTAAAGTTGCGTGTGCCAGGGG	PRTG	ENSG00000166450	-0.3161778704903667	[929]	[136,194,348]	-3	hSpCas9	negative selection	791072
55682395	55682418	15	+	26627737	DLD1	viability	TTTACGTCGGTGGGCTACAGTGG	PRTG	ENSG00000166450	0.03697022106457215	[760]	[234,284,217]	0	hSpCas9	negative selection	791073
55683786	55683809	15	-	26627737	DLD1	viability	CTCTACCTATGACTATGGACAGG	PRTG	ENSG00000166450	0.9638256596528381	[407]	[205,384,172]	8	hSpCas9	negative selection	791074
55742819	55742842	15	+	26627737	DLD1	viability	CAGAAGAAAGCGCGCCCACCTGG	PRTG	ENSG00000166450	1.0619085475101493	[367]	[162,337,225]	8	hSpCas9	negative selection	791075
55673594	55673617	15	+	26627737	GBM cells	viability after 5 days	TTTGGCTGGGATTGGCAGCCAGG	PRTG	ENSG00000166450	0.9363885803043482	[94]	[71,122]	9	hSpCas9	negative selection	873385
55677870	55677893	15	+	26627737	GBM cells	viability after 5 days	AAGAATGGCTGAGCTTGACATGG	PRTG	ENSG00000166450	0.1386929284191763	[270]	[153,165]	2	hSpCas9	negative selection	873386
55680082	55680105	15	+	26627737	GBM cells	viability after 5 days	TGTAAAGTTGCGTGTGCCAGGGG	PRTG	ENSG00000166450	0.7424785351253751	[325]	[281,302]	8	hSpCas9	negative selection	873387
55682395	55682418	15	+	26627737	GBM cells	viability after 5 days	TTTACGTCGGTGGGCTACAGTGG	PRTG	ENSG00000166450	0.33454246893777606	[399]	[268,271]	5	hSpCas9	negative selection	873388
55683786	55683809	15	-	26627737	GBM cells	viability after 5 days	CTCTACCTATGACTATGGACAGG	PRTG	ENSG00000166450	-0.3054446236205008	[211]	[93,89]	-5	hSpCas9	negative selection	873389
55742819	55742842	15	+	26627737	GBM cells	viability after 5 days	CAGAAGAAAGCGCGCCCACCTGG	PRTG	ENSG00000166450	0.5638756976720617	[151]	[131,108]	7	hSpCas9	negative selection	873390
55673594	55673617	15	+	26627737	GBM cells	viability after 13 days	TTTGGCTGGGATTGGCAGCCAGG	PRTG	ENSG00000166450	0.8015051990774054	[94]	[112,70]	8	hSpCas9	negative selection	955700
55677870	55677893	15	+	26627737	GBM cells	viability after 13 days	AAGAATGGCTGAGCTTGACATGG	PRTG	ENSG00000166450	0.09680282773793242	[270]	[159,154]	1	hSpCas9	negative selection	955701
55680082	55680105	15	+	26627737	GBM cells	viability after 13 days	TGTAAAGTTGCGTGTGCCAGGGG	PRTG	ENSG00000166450	0.6531552840337691	[325]	[179,357]	7	hSpCas9	negative selection	955702
55682395	55682418	15	+	26627737	GBM cells	viability after 13 days	TTTACGTCGGTGGGCTACAGTGG	PRTG	ENSG00000166450	0.14385515338917754	[399]	[225,250]	1	hSpCas9	negative selection	955703
55683786	55683809	15	-	26627737	GBM cells	viability after 13 days	CTCTACCTATGACTATGGACAGG	PRTG	ENSG00000166450	-0.10603672121149155	[211]	[134,83]	-1	hSpCas9	negative selection	955704
55742819	55742842	15	+	26627737	GBM cells	viability after 13 days	CAGAAGAAAGCGCGCCCACCTGG	PRTG	ENSG00000166450	0.7446205366208767	[151]	[162,117]	8	hSpCas9	negative selection	955705
55673594	55673617	15	+	26627737	GBM cells	viability after 21 days	TTTGGCTGGGATTGGCAGCCAGG	PRTG	ENSG00000166450	1.4127325467641223	[94]	[162,113]	9	hSpCas9	negative selection	1038015
55677870	55677893	15	+	26627737	GBM cells	viability after 21 days	AAGAATGGCTGAGCTTGACATGG	PRTG	ENSG00000166450	0.9624325421266653	[270]	[312,262]	8	hSpCas9	negative selection	1038016
55680082	55680105	15	+	26627737	GBM cells	viability after 21 days	TGTAAAGTTGCGTGTGCCAGGGG	PRTG	ENSG00000166450	1.4774366258573464	[325]	[500,485]	9	hSpCas9	negative selection	1038017
55682395	55682418	15	+	26627737	GBM cells	viability after 21 days	TTTACGTCGGTGGGCTACAGTGG	PRTG	ENSG00000166450	0.7344949794391062	[399]	[359,362]	7	hSpCas9	negative selection	1038018
55683786	55683809	15	-	26627737	GBM cells	viability after 21 days	CTCTACCTATGACTATGGACAGG	PRTG	ENSG00000166450	-0.5487845011589021	[211]	[84,72]	-5	hSpCas9	negative selection	1038019
55742819	55742842	15	+	26627737	GBM cells	viability after 21 days	CAGAAGAAAGCGCGCCCACCTGG	PRTG	ENSG00000166450	0.9824100889419456	[151]	[182,144]	8	hSpCas9	negative selection	1038020
55673594	55673617	15	+	26627737	RPE1	viability after 9 days	TTTGGCTGGGATTGGCAGCCAGG	PRTG	ENSG00000166450	1.7624967845731694	[338]	[339,385]	8	hSpCas9	negative selection	1120330
55677870	55677893	15	+	26627737	RPE1	viability after 9 days	AAGAATGGCTGAGCTTGACATGG	PRTG	ENSG00000166450	-1.1550189029833464	[1254]	[206,136]	-7	hSpCas9	negative selection	1120331
55680082	55680105	15	+	26627737	RPE1	viability after 9 days	TGTAAAGTTGCGTGTGCCAGGGG	PRTG	ENSG00000166450	0.05389193171001461	[2501]	[682,980]	0	hSpCas9	negative selection	1120332
55682395	55682418	15	+	26627737	RPE1	viability after 9 days	TTTACGTCGGTGGGCTACAGTGG	PRTG	ENSG00000166450	1.3438137149705875	[624]	[445,561]	7	hSpCas9	negative selection	1120333
55683786	55683809	15	-	26627737	RPE1	viability after 9 days	CTCTACCTATGACTATGGACAGG	PRTG	ENSG00000166450	-1.0877146022442128	[1164]	[130,223]	-7	hSpCas9	negative selection	1120334
55742819	55742842	15	+	26627737	RPE1	viability after 9 days	CAGAAGAAAGCGCGCCCACCTGG	PRTG	ENSG00000166450	0.5012167256107942	[506]	[273,160]	3	hSpCas9	negative selection	1120335
55673594	55673617	15	+	26627737	RPE1	viability after 12 days	TTTGGCTGGGATTGGCAGCCAGG	PRTG	ENSG00000166450	1.809545036545856	[338]	[259,381]	8	hSpCas9	negative selection	1202645
55677870	55677893	15	+	26627737	RPE1	viability after 12 days	AAGAATGGCTGAGCTTGACATGG	PRTG	ENSG00000166450	-0.7853869570178271	[1254]	[199,190]	-5	hSpCas9	negative selection	1202646
55680082	55680105	15	+	26627737	RPE1	viability after 12 days	TGTAAAGTTGCGTGTGCCAGGGG	PRTG	ENSG00000166450	-0.23931120341679568	[2501]	[618,516]	-2	hSpCas9	negative selection	1202647
55682395	55682418	15	+	26627737	RPE1	viability after 12 days	TTTACGTCGGTGGGCTACAGTGG	PRTG	ENSG00000166450	1.6189870783912093	[624]	[541,487]	8	hSpCas9	negative selection	1202648
55683786	55683809	15	-	26627737	RPE1	viability after 12 days	CTCTACCTATGACTATGGACAGG	PRTG	ENSG00000166450	-0.15220657914224056	[1164]	[201,365]	-1	hSpCas9	negative selection	1202649
55742819	55742842	15	+	26627737	RPE1	viability after 12 days	CAGAAGAAAGCGCGCCCACCTGG	PRTG	ENSG00000166450	-0.9776261782762328	[506]	[108,26]	-6	hSpCas9	negative selection	1202650
55673594	55673617	15	+	26627737	RPE1	viability after 15 days	TTTGGCTGGGATTGGCAGCCAGG	PRTG	ENSG00000166450	1.5329043223275631	[338]	[277,276]	7	hSpCas9	negative selection	1284960
55677870	55677893	15	+	26627737	RPE1	viability after 15 days	AAGAATGGCTGAGCTTGACATGG	PRTG	ENSG00000166450	-0.5569791529621132	[1254]	[251,230]	-4	hSpCas9	negative selection	1284961
55680082	55680105	15	+	26627737	RPE1	viability after 15 days	TGTAAAGTTGCGTGTGCCAGGGG	PRTG	ENSG00000166450	0.22123992722420693	[2501]	[905,746]	1	hSpCas9	negative selection	1284962
55682395	55682418	15	+	26627737	RPE1	viability after 15 days	TTTACGTCGGTGGGCTACAGTGG	PRTG	ENSG00000166450	1.394238686077359	[624]	[536,394]	7	hSpCas9	negative selection	1284963
55683786	55683809	15	-	26627737	RPE1	viability after 15 days	CTCTACCTATGACTATGGACAGG	PRTG	ENSG00000166450	-0.6308515142988466	[1164]	[53,365]	-4	hSpCas9	negative selection	1284964
55742819	55742842	15	+	26627737	RPE1	viability after 15 days	CAGAAGAAAGCGCGCCCACCTGG	PRTG	ENSG00000166450	-0.32471824503656754	[506]	[169,60]	-2	hSpCas9	negative selection	1284965
55673594	55673617	15	+	26627737	RPE1	viability after 18 days	TTTGGCTGGGATTGGCAGCCAGG	PRTG	ENSG00000166450	1.9897457157160179	[338]	[358,367]	8	hSpCas9	negative selection	1367275
55677870	55677893	15	+	26627737	RPE1	viability after 18 days	AAGAATGGCTGAGCTTGACATGG	PRTG	ENSG00000166450	-0.04183883272856859	[1254]	[299,359]	0	hSpCas9	negative selection	1367276
55680082	55680105	15	+	26627737	RPE1	viability after 18 days	TGTAAAGTTGCGTGTGCCAGGGG	PRTG	ENSG00000166450	-0.2691946061625381	[2501]	[480,644]	-2	hSpCas9	negative selection	1367277
55682395	55682418	15	+	26627737	RPE1	viability after 18 days	TTTACGTCGGTGGGCTACAGTGG	PRTG	ENSG00000166450	1.9297479473923282	[624]	[703,576]	8	hSpCas9	negative selection	1367278
55683786	55683809	15	-	26627737	RPE1	viability after 18 days	CTCTACCTATGACTATGGACAGG	PRTG	ENSG00000166450	-0.3911516639740896	[1164]	[129,356]	-2	hSpCas9	negative selection	1367279
55742819	55742842	15	+	26627737	RPE1	viability after 18 days	CAGAAGAAAGCGCGCCCACCTGG	PRTG	ENSG00000166450	0.5006696377437593	[506]	[268,112]	3	hSpCas9	negative selection	1367280
55673594	55673617	15	+	26627737	HeLa	viability after 8 days	TTTGGCTGGGATTGGCAGCCAGG	PRTG	ENSG00000166450	-0.4555821288189021	[316]	[99,150,53]	-4	hSpCas9	negative selection	1449590
55677870	55677893	15	+	26627737	HeLa	viability after 8 days	AAGAATGGCTGAGCTTGACATGG	PRTG	ENSG00000166450	1.0531120174783064	[236]	[280,165,209]	7	hSpCas9	negative selection	1449591
55680082	55680105	15	+	26627737	HeLa	viability after 8 days	TGTAAAGTTGCGTGTGCCAGGGG	PRTG	ENSG00000166450	0.6665465874469958	[550]	[412,431,308]	6	hSpCas9	negative selection	1449592
55682395	55682418	15	+	26627737	HeLa	viability after 8 days	TTTACGTCGGTGGGCTACAGTGG	PRTG	ENSG00000166450	0.13149757639251408	[474]	[186,233,247]	1	hSpCas9	negative selection	1449593
55683786	55683809	15	-	26627737	HeLa	viability after 8 days	CTCTACCTATGACTATGGACAGG	PRTG	ENSG00000166450	-0.13974091259830557	[215]	[165,100,11]	-1	hSpCas9	negative selection	1449594
55742819	55742842	15	+	26627737	HeLa	viability after 8 days	CAGAAGAAAGCGCGCCCACCTGG	PRTG	ENSG00000166450	-0.7322505466118026	[541]	[26,281,94]	-6	hSpCas9	negative selection	1449595
55673594	55673617	15	+	26627737	HeLa	viability after 12 days	TTTGGCTGGGATTGGCAGCCAGG	PRTG	ENSG00000166450	-0.5899757883729666	[316]	[61,99,96]	-5	hSpCas9	negative selection	1531905
55677870	55677893	15	+	26627737	HeLa	viability after 12 days	AAGAATGGCTGAGCTTGACATGG	PRTG	ENSG00000166450	0.8916428405654917	[236]	[224,109,218]	7	hSpCas9	negative selection	1531906
55680082	55680105	15	+	26627737	HeLa	viability after 12 days	TGTAAAGTTGCGTGTGCCAGGGG	PRTG	ENSG00000166450	0.5457073332507574	[550]	[429,275,299]	4	hSpCas9	negative selection	1531907
55682395	55682418	15	+	26627737	HeLa	viability after 12 days	TTTACGTCGGTGGGCTACAGTGG	PRTG	ENSG00000166450	-0.17638527608875512	[474]	[82,234,193]	-1	hSpCas9	negative selection	1531908
55683786	55683809	15	-	26627737	HeLa	viability after 12 days	CTCTACCTATGACTATGGACAGG	PRTG	ENSG00000166450	0.6587903123406866	[215]	[215,83,130]	5	hSpCas9	negative selection	1531909
55742819	55742842	15	+	26627737	HeLa	viability after 12 days	CAGAAGAAAGCGCGCCCACCTGG	PRTG	ENSG00000166450	-0.6844996255326501	[541]	[270,34,126]	-6	hSpCas9	negative selection	1531910
55673594	55673617	15	+	26627737	HeLa	viability after 15 days	TTTGGCTGGGATTGGCAGCCAGG	PRTG	ENSG00000166450	-0.7730227616706342	[316]	[30,85,112]	-6	hSpCas9	negative selection	1614220
55677870	55677893	15	+	26627737	HeLa	viability after 15 days	AAGAATGGCTGAGCTTGACATGG	PRTG	ENSG00000166450	0.7169330136379835	[236]	[109,127,244]	5	hSpCas9	negative selection	1614221
55680082	55680105	15	+	26627737	HeLa	viability after 15 days	TGTAAAGTTGCGTGTGCCAGGGG	PRTG	ENSG00000166450	0.33913790146328876	[550]	[189,456,198]	3	hSpCas9	negative selection	1614222
55682395	55682418	15	+	26627737	HeLa	viability after 15 days	TTTACGTCGGTGGGCTACAGTGG	PRTG	ENSG00000166450	-0.20114575129589007	[474]	[48,302,152]	-2	hSpCas9	negative selection	1614223
55683786	55683809	15	-	26627737	HeLa	viability after 15 days	CTCTACCTATGACTATGGACAGG	PRTG	ENSG00000166450	0.01604495745867507	[215]	[160,49,51]	0	hSpCas9	negative selection	1614224
55742819	55742842	15	+	26627737	HeLa	viability after 15 days	CAGAAGAAAGCGCGCCCACCTGG	PRTG	ENSG00000166450	-0.19943858397797415	[541]	[262,78,236]	-2	hSpCas9	negative selection	1614225
55673594	55673617	15	+	26627737	HeLa	viability after 18 days	TTTGGCTGGGATTGGCAGCCAGG	PRTG	ENSG00000166450	-0.7629243179045226	[316]	[21,70,112]	-6	hSpCas9	negative selection	1696535
55677870	55677893	15	+	26627737	HeLa	viability after 18 days	AAGAATGGCTGAGCTTGACATGG	PRTG	ENSG00000166450	0.6867044485821991	[236]	[68,103,244]	5	hSpCas9	negative selection	1696536
55680082	55680105	15	+	26627737	HeLa	viability after 18 days	TGTAAAGTTGCGTGTGCCAGGGG	PRTG	ENSG00000166450	0.32598296129159515	[550]	[121,378,198]	2	hSpCas9	negative selection	1696537
55682395	55682418	15	+	26627737	HeLa	viability after 18 days	TTTACGTCGGTGGGCTACAGTGG	PRTG	ENSG00000166450	-0.2224261689835771	[474]	[27,250,152]	-2	hSpCas9	negative selection	1696538
55683786	55683809	15	-	26627737	HeLa	viability after 18 days	CTCTACCTATGACTATGGACAGG	PRTG	ENSG00000166450	-0.10524820254324085	[215]	[95,38,51]	-1	hSpCas9	negative selection	1696539
55742819	55742842	15	+	26627737	HeLa	viability after 18 days	CAGAAGAAAGCGCGCCCACCTGG	PRTG	ENSG00000166450	-0.24410713102674822	[541]	[166,62,236]	-2	hSpCas9	negative selection	1696540
55673594	55673617	15	+	26627737	HCT116	viability after 6 days	TTTGGCTGGGATTGGCAGCCAGG	PRTG	ENSG00000166450	-0.5122132539900952	[597]	[43,77]	-3	hSpCas9	negative selection	1778850
55677870	55677893	15	+	26627737	HCT116	viability after 6 days	AAGAATGGCTGAGCTTGACATGG	PRTG	ENSG00000166450	2.610241016874014	[58]	[113,24]	9	hSpCas9	negative selection	1778851
55680082	55680105	15	+	26627737	HCT116	viability after 6 days	TGTAAAGTTGCGTGTGCCAGGGG	PRTG	ENSG00000166450	0.2574100292969981	[679]	[237,66]	1	hSpCas9	negative selection	1778852
55682395	55682418	15	+	26627737	HCT116	viability after 6 days	TTTACGTCGGTGGGCTACAGTGG	PRTG	ENSG00000166450	0.31432096290496636	[1238]	[276,222]	1	hSpCas9	negative selection	1778853
55683786	55683809	15	-	26627737	HCT116	viability after 6 days	CTCTACCTATGACTATGGACAGG	PRTG	ENSG00000166450	-0.1756803443125089	[513]	[164,19]	-1	hSpCas9	negative selection	1778854
55742819	55742842	15	+	26627737	HCT116	viability after 6 days	CAGAAGAAAGCGCGCCCACCTGG	PRTG	ENSG00000166450	0.8470143450234823	[539]	[75,194]	4	hSpCas9	negative selection	1778855
55673594	55673617	15	+	26627737	HCT116	viability after 8 days	TTTGGCTGGGATTGGCAGCCAGG	PRTG	ENSG00000166450	1.1138481554900739	[65]	[60,111,62]	8	hSpCas9	negative selection	1861165
55677870	55677893	15	+	26627737	HCT116	viability after 8 days	AAGAATGGCTGAGCTTGACATGG	PRTG	ENSG00000166450	-0.4551147671163629	[430]	[192,147,178]	-5	hSpCas9	negative selection	1861166
55680082	55680105	15	+	26627737	HCT116	viability after 8 days	TGTAAAGTTGCGTGTGCCAGGGG	PRTG	ENSG00000166450	-0.3948612459481422	[507]	[235,263,139]	-5	hSpCas9	negative selection	1861167
55682395	55682418	15	+	26627737	HCT116	viability after 8 days	TTTACGTCGGTGGGCTACAGTGG	PRTG	ENSG00000166450	-0.8457234638812522	[632]	[222,184,174]	-8	hSpCas9	negative selection	1861168
55683786	55683809	15	-	26627737	HCT116	viability after 8 days	CTCTACCTATGACTATGGACAGG	PRTG	ENSG00000166450	0.7932120744441397	[163]	[96,153,216]	7	hSpCas9	negative selection	1861169
55742819	55742842	15	+	26627737	HCT116	viability after 8 days	CAGAAGAAAGCGCGCCCACCTGG	PRTG	ENSG00000166450	1.1063106618248992	[156]	[160,267,129]	8	hSpCas9	negative selection	1861170
55673594	55673617	15	+	26627737	HCT116	viability after 9 days	TTTGGCTGGGATTGGCAGCCAGG	PRTG	ENSG00000166450	-0.38689023646966825	[597]	[120,122]	-3	hSpCas9	negative selection	1943480
55677870	55677893	15	+	26627737	HCT116	viability after 9 days	AAGAATGGCTGAGCTTGACATGG	PRTG	ENSG00000166450	3.478081246113959	[58]	[93,239]	9	hSpCas9	negative selection	1943481
55680082	55680105	15	+	26627737	HCT116	viability after 9 days	TGTAAAGTTGCGTGTGCCAGGGG	PRTG	ENSG00000166450	0.9865129755660865	[679]	[299,406]	6	hSpCas9	negative selection	1943482
55682395	55682418	15	+	26627737	HCT116	viability after 9 days	TTTACGTCGGTGGGCTACAGTGG	PRTG	ENSG00000166450	-1.0199672663948938	[1238]	[218,118]	-6	hSpCas9	negative selection	1943483
55683786	55683809	15	-	26627737	HCT116	viability after 9 days	CTCTACCTATGACTATGGACAGG	PRTG	ENSG00000166450	-0.848097152883788	[513]	[30,111]	-5	hSpCas9	negative selection	1943484
55742819	55742842	15	+	26627737	HCT116	viability after 9 days	CAGAAGAAAGCGCGCCCACCTGG	PRTG	ENSG00000166450	1.0634769383687173	[539]	[173,401]	7	hSpCas9	negative selection	1943485
55673594	55673617	15	+	26627737	HCT116	viability after 12 days	TTTGGCTGGGATTGGCAGCCAGG	PRTG	ENSG00000166450	1.6427154464244573	[65]	[72,148,106]	9	hSpCas9	negative selection	2025795
55677870	55677893	15	+	26627737	HCT116	viability after 12 days	AAGAATGGCTGAGCTTGACATGG	PRTG	ENSG00000166450	-0.405571671060997	[430]	[201,118,187]	-4	hSpCas9	negative selection	2025796
55680082	55680105	15	+	26627737	HCT116	viability after 12 days	TGTAAAGTTGCGTGTGCCAGGGG	PRTG	ENSG00000166450	0.1944804151277022	[507]	[350,202,355]	2	hSpCas9	negative selection	2025797
55682395	55682418	15	+	26627737	HCT116	viability after 12 days	TTTACGTCGGTGGGCTACAGTGG	PRTG	ENSG00000166450	-0.6497904972498194	[632]	[168,93,373]	-6	hSpCas9	negative selection	2025798
55683786	55683809	15	-	26627737	HCT116	viability after 12 days	CTCTACCTATGACTATGGACAGG	PRTG	ENSG00000166450	0.5377235060525425	[163]	[108,134,132]	5	hSpCas9	negative selection	2025799
55742819	55742842	15	+	26627737	HCT116	viability after 12 days	CAGAAGAAAGCGCGCCCACCTGG	PRTG	ENSG00000166450	0.7792655441912774	[156]	[145,123,153]	7	hSpCas9	negative selection	2025800
55673594	55673617	15	+	26627737	HCT116	viability after 15 days	TTTGGCTGGGATTGGCAGCCAGG	PRTG	ENSG00000166450	1.7870829187008779	[65]	[187,130,80]	9	hSpCas9	negative selection	2108110
55677870	55677893	15	+	26627737	HCT116	viability after 15 days	AAGAATGGCTGAGCTTGACATGG	PRTG	ENSG00000166450	-0.33091305229137585	[430]	[225,177,189]	-3	hSpCas9	negative selection	2108111
55680082	55680105	15	+	26627737	HCT116	viability after 15 days	TGTAAAGTTGCGTGTGCCAGGGG	PRTG	ENSG00000166450	0.44955162058951315	[507]	[231,380,559]	4	hSpCas9	negative selection	2108112
55682395	55682418	15	+	26627737	HCT116	viability after 15 days	TTTACGTCGGTGGGCTACAGTGG	PRTG	ENSG00000166450	-0.9481901862782729	[632]	[247,95,227]	-7	hSpCas9	negative selection	2108113
55683786	55683809	15	-	26627737	HCT116	viability after 15 days	CTCTACCTATGACTATGGACAGG	PRTG	ENSG00000166450	0.7527825308683056	[163]	[107,207,153]	6	hSpCas9	negative selection	2108114
55742819	55742842	15	+	26627737	HCT116	viability after 15 days	CAGAAGAAAGCGCGCCCACCTGG	PRTG	ENSG00000166450	1.0523640399452487	[156]	[213,140,208]	8	hSpCas9	negative selection	2108115
55673594	55673617	15	+	26627737	HCT116	viability after 18 days	TTTGGCTGGGATTGGCAGCCAGG	PRTG	ENSG00000166450	2.149587081127732	[65]	[192,100,132]	9	hSpCas9	negative selection	2190425
55677870	55677893	15	+	26627737	HCT116	viability after 18 days	AAGAATGGCTGAGCTTGACATGG	PRTG	ENSG00000166450	-0.10000872797565175	[430]	[276,153,152]	-1	hSpCas9	negative selection	2190426
55680082	55680105	15	+	26627737	HCT116	viability after 18 days	TGTAAAGTTGCGTGTGCCAGGGG	PRTG	ENSG00000166450	0.7561924197889991	[507]	[368,445,427]	6	hSpCas9	negative selection	2190427
55682395	55682418	15	+	26627737	HCT116	viability after 18 days	TTTACGTCGGTGGGCTACAGTGG	PRTG	ENSG00000166450	-0.6317993744314399	[632]	[150,100,353]	-5	hSpCas9	negative selection	2190428
55683786	55683809	15	-	26627737	HCT116	viability after 18 days	CTCTACCTATGACTATGGACAGG	PRTG	ENSG00000166450	0.4724154035488985	[163]	[70,108,151]	4	hSpCas9	negative selection	2190429
55742819	55742842	15	+	26627737	HCT116	viability after 18 days	CAGAAGAAAGCGCGCCCACCTGG	PRTG	ENSG00000166450	1.3953585276205973	[156]	[113,268,211]	8	hSpCas9	negative selection	2190430
55693124	55693147	15	+	25494202	A375	resistance to PLX-4720 (puromycin)	CAGGCGTGAGCCACCGCGCCAAG	PRTG	ENSG00000166450	-0.8581528486253212	[26,35]	[2,3]	-5	dCas9-VP64	positive selection	2392049
55697679	55697702	15	+	25494202	A375	resistance to PLX-4720 (puromycin)	AGCGTTTCACCATGTTGGCCAAG	PRTG	ENSG00000166450	0.44435531486280433	[154,264]	[28,99]	2	dCas9-VP64	positive selection	2404935
55726127	55726150	15	+	25494202	A375	resistance to PLX-4720 (puromycin)	GAGACGGGGTTTCACCATGTGGG	PRTG	ENSG00000166450	1.7100356304154607	[4,2]	[3,0]	6	dCas9-VP64	positive selection	2409648
55663583	55663606	15	-	25494202	A375	resistance to PLX-4720 (puromycin)	AGCGCCATTGCACTCCAGCCAGG	PRTG	ENSG00000166450	3.6537831084481405	[32,65]	[34,252]	9	dCas9-VP64	positive selection	2411010
55732261	55732284	15	+	25494202	A375	resistance to PLX-4720 (puromycin)	TCACTGCTACCTCCGCCTCCTGG	PRTG	ENSG00000166450	0.2334890985798408	[352,717]	[86,194]	1	dCas9-VP64	positive selection	2411900
55682588	55682611	15	+	25494202	A375	resistance to PLX-4720 (puromycin)	GAGTTTCACTCTTGTTGCCCCGG	PRTG	ENSG00000166450	1.0342323942437988	[48,24]	[15,15]	4	dCas9-VP64	positive selection	2423103
55730755	55730778	15	+	25494202	A375	resistance to PLX-4720 (puromycin)	GCGCCACTGCACTCCAACCTGGG	PRTG	ENSG00000166450	2.1497742914119513	[2,11]	[5,8]	7	dCas9-VP64	positive selection	2439356
55650890	55650913	15	-	25494202	A375	resistance to PLX-4720 (puromycin)	TCACTACAACCTCTGCCTCCTGG	PRTG	ENSG00000166450	0.3736894149735144	[619,564]	[67,277]	1	dCas9-VP64	positive selection	2444065
55664214	55664237	15	+	25494202	A375	resistance to PLX-4720 (puromycin)	TTACTGCAACCTCCGCCCCCCAG	PRTG	ENSG00000166450	-1.8511650686779566	[352,350]	[21,19]	-8	dCas9-VP64	positive selection	2452184
55726025	55726048	15	-	25494202	A375	resistance to PLX-4720 (puromycin)	TGCTTGAACCTGGGAGGCGGAAG	PRTG	ENSG00000166450	-0.49448069816640183	[10,25]	[2,1]	-2	dCas9-VP64	positive selection	2460609
55711197	55711220	15	+	25494202	A375	resistance to PLX-4720 (puromycin)	CAGGCGTGAGCCACTGCGTCCGG	PRTG	ENSG00000166450	-1.453588368366345	[188,63]	[8,9]	-8	dCas9-VP64	positive selection	2463530
55743083	55743106	15	+	25494202	A375	resistance to PLX-4720 (puromycin)	CGGCGAGGCTGGTGCTCGGACGG	PRTG	ENSG00000166450	-0.3570758757130688	[1,289]	[0,50]	-2	dCas9-VP64	positive selection	2470725
55743060	55743083	15	+	25494202	A375	resistance to PLX-4720 (puromycin)	CGGCGTGGCGAGCGTCTCTGCGG	PRTG	ENSG00000166450	1.6052458893150379	[2,19]	[12,1]	6	dCas9-VP64	positive selection	2470726
55693124	55693147	15	+	25494202	A375	resistance to PLX-4720 (zeocin)	CAGGCGTGAGCCACCGCGCCAAG	PRTG	ENSG00000166450	-0.2201981089703296	[184,135]	[60,29]	-2	dCas9-VP64	positive selection	2487304
55697679	55697702	15	+	25494202	A375	resistance to PLX-4720 (zeocin)	AGCGTTTCACCATGTTGGCCAAG	PRTG	ENSG00000166450	-0.3639755036387148	[260,201]	[38,76]	-4	dCas9-VP64	positive selection	2500190
55726127	55726150	15	+	25494202	A375	resistance to PLX-4720 (zeocin)	GAGACGGGGTTTCACCATGTGGG	PRTG	ENSG00000166450	-0.28524240662887035	[88,68]	[26,14]	-3	dCas9-VP64	positive selection	2504903
55663583	55663606	15	-	25494202	A375	resistance to PLX-4720 (zeocin)	AGCGCCATTGCACTCCAGCCAGG	PRTG	ENSG00000166450	1.263366329430324	[331,132]	[69,289]	7	dCas9-VP64	positive selection	2506265
55732261	55732284	15	+	25494202	A375	resistance to PLX-4720 (zeocin)	TCACTGCTACCTCCGCCTCCTGG	PRTG	ENSG00000166450	1.897179644919835	[262,271]	[154,486]	8	dCas9-VP64	positive selection	2507155
55682588	55682611	15	+	25494202	A375	resistance to PLX-4720 (zeocin)	GAGTTTCACTCTTGTTGCCCCGG	PRTG	ENSG00000166450	1.1207783393058013	[70,52]	[75,13]	7	dCas9-VP64	positive selection	2518358
55730755	55730778	15	+	25494202	A375	resistance to PLX-4720 (zeocin)	GCGCCACTGCACTCCAACCTGGG	PRTG	ENSG00000166450	0.6658120072320489	[88,38]	[30,34]	5	dCas9-VP64	positive selection	2534611
55650890	55650913	15	-	25494202	A375	resistance to PLX-4720 (zeocin)	TCACTACAACCTCTGCCTCCTGG	PRTG	ENSG00000166450	2.2699980135687987	[309,268]	[879,61]	8	dCas9-VP64	positive selection	2539320
55664214	55664237	15	+	25494202	A375	resistance to PLX-4720 (zeocin)	TTACTGCAACCTCCGCCCCCCAG	PRTG	ENSG00000166450	0.9477034237395038	[173,106]	[127,52]	6	dCas9-VP64	positive selection	2547439
55726025	55726048	15	-	25494202	A375	resistance to PLX-4720 (zeocin)	TGCTTGAACCTGGGAGGCGGAAG	PRTG	ENSG00000166450	-1.2686416065166946	[152,79]	[23,7]	-9	dCas9-VP64	positive selection	2555864
55711197	55711220	15	+	25494202	A375	resistance to PLX-4720 (zeocin)	CAGGCGTGAGCCACTGCGTCCGG	PRTG	ENSG00000166450	0.10976477844408938	[73,10]	[24,4]	0	dCas9-VP64	positive selection	2558785
55743083	55743106	15	+	25494202	A375	resistance to PLX-4720 (zeocin)	CGGCGAGGCTGGTGCTCGGACGG	PRTG	ENSG00000166450	-0.7611228790857185	[22,324]	[7,55]	-7	dCas9-VP64	positive selection	2565980
55743060	55743083	15	+	25494202	A375	resistance to PLX-4720 (zeocin)	CGGCGTGGCGAGCGTCTCTGCGG	PRTG	ENSG00000166450	1.5731345956434428	[78,96]	[143,29]	8	dCas9-VP64	positive selection	2565981
55673583	55673606	15	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	ATCCCAGCCAAATATCGGCGGGG	PRTG	ENSG00000166450	-0.24448847204896743	[3,3]	[3,1]	-3	hSpCas9	positive selection	3014165
55683825	55683848	15	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CCCATGTTATGACTGCAGGAGGG	PRTG	ENSG00000166450	0.11782575173909099	[3,3]	[1,3]	2	hSpCas9	positive selection	3014166
55682445	55682468	15	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GATCTATGATGTCAGCCAAAGGG	PRTG	ENSG00000166450	0.26547119550999887	[3,3]	[4,3]	5	hSpCas9	positive selection	3014167
55742874	55742897	15	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCGCGGAGCAGCATCCCCGGCGG	PRTG	ENSG00000166450	-0.7178958725110254	[3,2]	[0,1]	-8	hSpCas9	positive selection	3014168
55673583	55673606	15	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	ATCCCAGCCAAATATCGGCGGGG	PRTG	ENSG00000166450	-0.45180843066741	[3,3]	[3,0]	-6	hSpCas9	positive selection	3082023
55683825	55683848	15	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CCCATGTTATGACTGCAGGAGGG	PRTG	ENSG00000166450	0.27267236014818036	[3,3]	[2,2]	5	hSpCas9	positive selection	3082024
55682445	55682468	15	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GATCTATGATGTCAGCCAAAGGG	PRTG	ENSG00000166450	0.10768221956504204	[3,3]	[4,2]	2	hSpCas9	positive selection	3082025
55742874	55742897	15	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCGCGGAGCAGCATCCCCGGCGG	PRTG	ENSG00000166450	-0.32583708419417656	[3,3]	[2,0]	-5	hSpCas9	positive selection	3082026
55742870	55742893		+	24336571	A375	resistance to PLX after 7 days	AGCGCGCGGAGCAGCATCCCCGG	PRTG	ENSG00000166450	-0.08818543285798008	[19,18]	[16,18]	-3	hSpCas9	positive selection	3138241
55740595	55740618		-	24336571	A375	resistance to PLX after 7 days	CCCAGTCGTTTTAGATTGCCAGG	PRTG	ENSG00000166450	0.04754461943259762	[13,11]	[11,13]	1	hSpCas9	positive selection	3138242
55740453	55740476		-	24336571	A375	resistance to PLX after 7 days	CGAGGAGAGCAGTCCGATGAAGG	PRTG	ENSG00000166450	-0.24316577223965785	[5,4]	[3,3]	-7	hSpCas9	positive selection	3138243
55742870	55742893		+	24336571	A375	resistance to PLX after 14 days	AGCGCGCGGAGCAGCATCCCCGG	PRTG	ENSG00000166450	-0.6695510988409444	[22,23]	[7,4]	-7	hSpCas9	positive selection	3196034
55740595	55740618		-	24336571	A375	resistance to PLX after 14 days	CCCAGTCGTTTTAGATTGCCAGG	PRTG	ENSG00000166450	0.29287052252962287	[17,10]	[7,7]	3	hSpCas9	positive selection	3196035
55740453	55740476		-	24336571	A375	resistance to PLX after 14 days	CGAGGAGAGCAGTCCGATGAAGG	PRTG	ENSG00000166450	-0.020286720232434607	[4,5]	[1,1]	0	hSpCas9	positive selection	3196036
55742870	55742893		+	24336571	A375	viability after 7 days	AGCGCGCGGAGCAGCATCCCCGG	PRTG	ENSG00000166450	-0.06082876238407009	[20]	[19,18]	-1	hSpCas9	negative selection	3253827
55740595	55740618		-	24336571	A375	viability after 7 days	CCCAGTCGTTTTAGATTGCCAGG	PRTG	ENSG00000166450	0.2713040691125547	[10]	[13,11]	4	hSpCas9	negative selection	3253828
55740453	55740476		-	24336571	A375	viability after 7 days	CGAGGAGAGCAGTCCGATGAAGG	PRTG	ENSG00000166450	0.1030406533941548	[4]	[5,4]	1	hSpCas9	negative selection	3253829
55742870	55742893		+	24336571	A375	viability after 14 days	AGCGCGCGGAGCAGCATCCCCGG	PRTG	ENSG00000166450	0.2173339888475131	[20]	[22,23]	3	hSpCas9	negative selection	3311620
55740595	55740618		-	24336571	A375	viability after 14 days	CCCAGTCGTTTTAGATTGCCAGG	PRTG	ENSG00000166450	0.4671797820251572	[10]	[17,10]	6	hSpCas9	negative selection	3311621
55740453	55740476		-	24336571	A375	viability after 14 days	CGAGGAGAGCAGTCCGATGAAGG	PRTG	ENSG00000166450	0.14417575302287577	[4]	[4,5]	1	hSpCas9	negative selection	3311622
55683869	55683892	15	+	27383988	293T	resistance to West Nile virus (flavivirus)	ATCGAGCAACTCCACCTTCGTGG	PRTG	ENSG00000166450	-1.0646018834415274	[319,319]	[0,0]	-7	hSpCas9	positive selection	3387855
55742902	55742925	15	-	27383988	293T	resistance to West Nile virus (flavivirus)	CTCCTCTGCGACCCCTCGCCCGG	PRTG	ENSG00000166450	0.6574133692587072	[193,193]	[1,1]	3	hSpCas9	positive selection	3387856
55742900	55742923	15	+	27383988	293T	resistance to West Nile virus (flavivirus)	AGCCGGGCGAGGGGTCGCAGAGG	PRTG	ENSG00000166450	3.935398116558473	[9,9]	[0,0]	9	hSpCas9	positive selection	3387857
55673583	55673606	15	-	26780180	HT29	viability (Avana library 4 designs)	ATCCCAGCCAAATATCGGCGGGG	PRTG	ENSG00000166450	0.764296527202672	[]	[]	3	hSpCas9	negative selection	3452389
55683824	55683847	15	+	26780180	HT29	viability (Avana library 4 designs)	CCCATGTTATGACTGCAGGAGGG	PRTG	ENSG00000166450	1.64371429445351	[]	[]	6	hSpCas9	negative selection	3452390
55682445	55682468	15	-	26780180	HT29	viability (Avana library 4 designs)	GATCTATGATGTCAGCCAAAGGG	PRTG	ENSG00000166450	1.00716454524114	[]	[]	4	hSpCas9	negative selection	3452391
55742873	55742896	15	+	26780180	HT29	viability (Avana library 4 designs)	GCGCGGAGCAGCATCCCCGGCGG	PRTG	ENSG00000166450	0.279572186564378	[]	[]	1	hSpCas9	negative selection	3452392
55682445	55682468	15	-	26780180	A375	viability (Avana lentiCRISPRv2)	GATCTATGATGTCAGCCAAAGGG	PRTG	ENSG00000166450	-1.47274264620334	[]	[]	-2	hSpCas9	negative selection	3548740
55683824	55683847	15	+	26780180	A375	viability (Avana lentiCRISPRv2)	CCCATGTTATGACTGCAGGAGGG	PRTG	ENSG00000166450	3.61800443556218	[]	[]	6	hSpCas9	negative selection	3548741
55742873	55742896	15	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCGCGGAGCAGCATCCCCGGCGG	PRTG	ENSG00000166450	3.24775310237001	[]	[]	5	hSpCas9	negative selection	3548742
55673583	55673606	15	-	26780180	A375	viability (Avana lentiCRISPRv2)	ATCCCAGCCAAATATCGGCGGGG	PRTG	ENSG00000166450	-0.755059233315247	[]	[]	-1	hSpCas9	negative selection	3548743
55675522	55675545	15	-	26780180	A375	viability (Avana lentiCRISPRv2)	TGTGACACAGAATACTCTAGAGG	PRTG	ENSG00000166450	-2.45216329453584	[]	[]	-3	hSpCas9	negative selection	3548744
55742856	55742879	15	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCAGCAGGAGCAGGAGCGCGCGG	PRTG	ENSG00000166450	-4.91843589472628	[]	[]	-5	hSpCas9	negative selection	3548745
55682445	55682468	15	-	26780180	A375	viability (Avana lentiGuide)	GATCTATGATGTCAGCCAAAGGG	PRTG	ENSG00000166450	-3.6373396076051	[]	[]	-6	hSpCas9	negative selection	3657399
55683824	55683847	15	+	26780180	A375	viability (Avana lentiGuide)	CCCATGTTATGACTGCAGGAGGG	PRTG	ENSG00000166450	-5.11164789993306	[]	[]	-8	hSpCas9	negative selection	3657400
55742873	55742896	15	+	26780180	A375	viability (Avana lentiGuide)	GCGCGGAGCAGCATCCCCGGCGG	PRTG	ENSG00000166450	-1.60276980519345	[]	[]	-3	hSpCas9	negative selection	3657401
55673583	55673606	15	-	26780180	A375	viability (Avana lentiGuide)	ATCCCAGCCAAATATCGGCGGGG	PRTG	ENSG00000166450	2.6859703300233	[]	[]	3	hSpCas9	negative selection	3657402
55675522	55675545	15	-	26780180	A375	viability (Avana lentiGuide)	TGTGACACAGAATACTCTAGAGG	PRTG	ENSG00000166450	2.14856943213933	[]	[]	2	hSpCas9	negative selection	3657403
55742856	55742879	15	+	26780180	A375	viability (Avana lentiGuide)	GCAGCAGGAGCAGGAGCGCGCGG	PRTG	ENSG00000166450	24.0325470718589	[]	[]	9	hSpCas9	negative selection	3657404
55682445	55682468	15	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GATCTATGATGTCAGCCAAAGGG	PRTG	ENSG00000166450	-0.24665098857605255	[6]	[5,3]	-4	hSpCas9	positive selection	3766006
55683824	55683847	15	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CCCATGTTATGACTGCAGGAGGG	PRTG	ENSG00000166450	0.021799538848635586	[4]	[5,4]	0	hSpCas9	positive selection	3766007
55742873	55742896	15	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCGCGGAGCAGCATCCCCGGCGG	PRTG	ENSG00000166450	0.3114292750358782	[3]	[5,3]	8	hSpCas9	positive selection	3766008
55673583	55673606	15	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ATCCCAGCCAAATATCGGCGGGG	PRTG	ENSG00000166450	0.03616456539405613	[5]	[5,6]	0	hSpCas9	positive selection	3766009
55675522	55675545	15	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TGTGACACAGAATACTCTAGAGG	PRTG	ENSG00000166450	-0.17373415563632838	[6]	[5,5]	-3	hSpCas9	positive selection	3766010
55742856	55742879	15	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCAGCAGGAGCAGGAGCGCGCGG	PRTG	ENSG00000166450	-0.6054827132816258	[3]	[1,2]	-7	hSpCas9	positive selection	3766011
55682445	55682468	15	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GATCTATGATGTCAGCCAAAGGG	PRTG	ENSG00000166450	0.2916829540824044	[5]	[5,5]	7	hSpCas9	positive selection	3874613
55683824	55683847	15	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CCCATGTTATGACTGCAGGAGGG	PRTG	ENSG00000166450	-0.2827401003793091	[4]	[3,3]	-4	hSpCas9	positive selection	3874614
55742873	55742896	15	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCGCGGAGCAGCATCCCCGGCGG	PRTG	ENSG00000166450	-0.48764111630923823	[4]	[1,3]	-6	hSpCas9	positive selection	3874615
55673583	55673606	15	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ATCCCAGCCAAATATCGGCGGGG	PRTG	ENSG00000166450	0.21485177882379794	[5]	[5,4]	5	hSpCas9	positive selection	3874616
55675522	55675545	15	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TGTGACACAGAATACTCTAGAGG	PRTG	ENSG00000166450	-0.18643991484765757	[5]	[4,3]	-3	hSpCas9	positive selection	3874617
55742856	55742879	15	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCAGCAGGAGCAGGAGCGCGCGG	PRTG	ENSG00000166450	-1.411034314967076	[4]	[0,1]	-9	hSpCas9	positive selection	3874618
55683820	55683843	15	+	26780180	A375	viability	AACTCCCATGTTATGACTGCAGG	PRTG	ENSG00000166450	1.75050731580861	[]	[]	9	hSpCas9	negative selection	3985051
55742900	55742923	15	+	26780180	A375	viability	AGCCGGGCGAGGGGTCGCAGAGG	PRTG	ENSG00000166450	0.549507311320414	[]	[]	1	hSpCas9	negative selection	3985052
55683869	55683892	15	+	26780180	A375	viability	ATCGAGCAACTCCACCTTCGTGG	PRTG	ENSG00000166450	0.815033786544934	[]	[]	3	hSpCas9	negative selection	3985053
55742902	55742925	15	-	26780180	A375	viability	CTCCTCTGCGACCCCTCGCCCGG	PRTG	ENSG00000166450	1.01863145124702	[]	[]	5	hSpCas9	negative selection	3985054
55740594	55740617	15	+	26780180	A375	viability	GCCTGGCAATCTAAAACGACTGG	PRTG	ENSG00000166450	0.662056463079132	[]	[]	2	hSpCas9	negative selection	3985055
55740571	55740594	15	-	26780180	A375	viability	TCACGGAGAAGTTCCTATTAAGG	PRTG	ENSG00000166450	1.12561632713809	[]	[]	5	hSpCas9	negative selection	3985056
55683820	55683843	15	+	26780180	HT29	viability (GeCKOv2 library)	AACTCCCATGTTATGACTGCAGG	PRTG	ENSG00000166450	1.50284504627851	[]	[]	7	hSpCas9	negative selection	4093017
55742900	55742923	15	+	26780180	HT29	viability (GeCKOv2 library)	AGCCGGGCGAGGGGTCGCAGAGG	PRTG	ENSG00000166450	0.670226607008274	[]	[]	2	hSpCas9	negative selection	4093018
55683869	55683892	15	+	26780180	HT29	viability (GeCKOv2 library)	ATCGAGCAACTCCACCTTCGTGG	PRTG	ENSG00000166450	0.505791323792763	[]	[]	1	hSpCas9	negative selection	4093019
55742902	55742925	15	-	26780180	HT29	viability (GeCKOv2 library)	CTCCTCTGCGACCCCTCGCCCGG	PRTG	ENSG00000166450	1.29206601122317	[]	[]	6	hSpCas9	negative selection	4093020
55740594	55740617	15	+	26780180	HT29	viability (GeCKOv2 library)	GCCTGGCAATCTAAAACGACTGG	PRTG	ENSG00000166450	1.18684034512617	[]	[]	6	hSpCas9	negative selection	4093021
55740571	55740594	15	-	26780180	HT29	viability (GeCKOv2 library)	TCACGGAGAAGTTCCTATTAAGG	PRTG	ENSG00000166450	0.324829688754377	[]	[]	0	hSpCas9	negative selection	4093022
55742870	55742893	15	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	AGCGCGCGGAGCAGCATCCCCGG	PRTG	ENSG00000166450	0.10686730053049298	[4]	[3,2]	2	hSpCas9	positive selection	4163456
55740595	55740618	15	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CCCAGTCGTTTTAGATTGCCAGG	PRTG	ENSG00000166450	0.22077923296798835	[3]	[2,2]	5	hSpCas9	positive selection	4163457
55740453	55740476	15	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CGAGGAGAGCAGTCCGATGAAGG	PRTG	ENSG00000166450	0.01536522225307102	[2]	[1,0]	0	hSpCas9	positive selection	4163458
55742870	55742893	15	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	AGCGCGCGGAGCAGCATCCCCGG	PRTG	ENSG00000166450	-0.11740470049680618	[4]	[0,0,5,0]	-2	hSpCas9	positive selection	4227478
55740595	55740618	15	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CCCAGTCGTTTTAGATTGCCAGG	PRTG	ENSG00000166450	1.1813426494847639	[1]	[1,3,1,0]	8	hSpCas9	positive selection	4227479
55740453	55740476	15	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CGAGGAGAGCAGTCCGATGAAGG	PRTG	ENSG00000166450	1.1531751245885704	[0]	[0,0,0,0]	8	hSpCas9	positive selection	4227480
55740594	55740617	15	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GCCTGGCAATCTAAAACGACTGG	PRTG	ENSG00000166450	0.029273360881344218	[2]	[1,1]	0	hSpCas9	positive selection	4292612
55683820	55683843	15	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AACTCCCATGTTATGACTGCAGG	PRTG	ENSG00000166450	-0.24507210265818932	[4]	[3,1]	-5	hSpCas9	positive selection	4292613
55740571	55740594	15	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TCACGGAGAAGTTCCTATTAAGG	PRTG	ENSG00000166450	0.16595487014608312	[2]	[3,1]	3	hSpCas9	positive selection	4292614
55683869	55683892	15	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ATCGAGCAACTCCACCTTCGTGG	PRTG	ENSG00000166450	0.18051485532124445	[4]	[4,2]	3	hSpCas9	positive selection	4356871
55742902	55742925	15	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CTCCTCTGCGACCCCTCGCCCGG	PRTG	ENSG00000166450	-0.11412278082181165	[3]	[2,1]	-2	hSpCas9	positive selection	4356872
55742900	55742923	15	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AGCCGGGCGAGGGGTCGCAGAGG	PRTG	ENSG00000166450	-0.403618648663121	[0]	[0,0]	-7	hSpCas9	positive selection	4356873
55673583	55673605	15	-	27760321	OCIAML3	viability	TCCCAGCCAAATATCGGCGGGG	PRTG	ENSG00000166450	-0.3898803268259647	[449,495]	[276,293]	-4	hSpCas9	negative selection	4431206
55680167	55680189	15	-	27760321	OCIAML3	viability	ATACTCGGGTACTTGGAAATGG	PRTG	ENSG00000166450	-1.471823591920097	[74,70]	[17,23]	-8	hSpCas9	negative selection	4431207
55682388	55682410	15	-	27760321	OCIAML3	viability	GCCCACCGACGTAAAAGTATGG	PRTG	ENSG00000166450	0.11578337694908991	[199,172]	[141,177]	1	hSpCas9	negative selection	4431208
55682477	55682499	15	-	27760321	OCIAML3	viability	GGATAACTGCCCTACCAACAGG	PRTG	ENSG00000166450	0.4276207998565993	[208,213]	[245,193]	5	hSpCas9	negative selection	4431209
55740595	55740617	15	+	27760321	OCIAML3	viability	CCTGGCAATCTAAAACGACTGG	PRTG	ENSG00000166450	-0.22339734360097757	[343,293]	[199,229]	-2	hSpCas9	negative selection	4431210
55673583	55673605	15	-	27760321	OCIAML2	viability	TCCCAGCCAAATATCGGCGGGG	PRTG	ENSG00000166450	0.5574431299678595	[449,495]	[473,689]	7	hSpCas9	negative selection	4514669
55680167	55680189	15	-	27760321	OCIAML2	viability	ATACTCGGGTACTTGGAAATGG	PRTG	ENSG00000166450	0.1806267651119895	[74,70]	[66,66]	2	hSpCas9	negative selection	4514670
55682388	55682410	15	-	27760321	OCIAML2	viability	GCCCACCGACGTAAAAGTATGG	PRTG	ENSG00000166450	0.8161269766186877	[199,172]	[191,360]	9	hSpCas9	negative selection	4514671
55682477	55682499	15	-	27760321	OCIAML2	viability	GGATAACTGCCCTACCAACAGG	PRTG	ENSG00000166450	0.5834703854256824	[208,213]	[209,319]	7	hSpCas9	negative selection	4514672
55740595	55740617	15	+	27760321	OCIAML2	viability	CCTGGCAATCTAAAACGACTGG	PRTG	ENSG00000166450	-0.5119985098558852	[343,293]	[122,255]	-5	hSpCas9	negative selection	4514673
55673583	55673605	15	-	27760321	MV411	viability	TCCCAGCCAAATATCGGCGGGG	PRTG	ENSG00000166450	0.22105281891708328	[449,495]	[202,611]	1	hSpCas9	negative selection	4598132
55680167	55680189	15	-	27760321	MV411	viability	ATACTCGGGTACTTGGAAATGG	PRTG	ENSG00000166450	-1.0315116509848297	[74,70]	[11,40]	-6	hSpCas9	negative selection	4598133
55682388	55682410	15	-	27760321	MV411	viability	GCCCACCGACGTAAAAGTATGG	PRTG	ENSG00000166450	-0.39119963592784024	[199,172]	[83,107]	-3	hSpCas9	negative selection	4598134
55682477	55682499	15	-	27760321	MV411	viability	GGATAACTGCCCTACCAACAGG	PRTG	ENSG00000166450	0.5371077141865828	[208,213]	[184,230]	4	hSpCas9	negative selection	4598135
55740595	55740617	15	+	27760321	MV411	viability	CCTGGCAATCTAAAACGACTGG	PRTG	ENSG00000166450	0.6331646949630609	[343,293]	[159,573]	5	hSpCas9	negative selection	4598136
55673583	55673605	15	-	27760321	HL60	viability	TCCCAGCCAAATATCGGCGGGG	PRTG	ENSG00000166450	0.6365746625094868	[449,495]	[639,567]	7	hSpCas9	negative selection	4681595
55680167	55680189	15	-	27760321	HL60	viability	ATACTCGGGTACTTGGAAATGG	PRTG	ENSG00000166450	0.6719346027642723	[74,70]	[81,108]	7	hSpCas9	negative selection	4681596
55682388	55682410	15	-	27760321	HL60	viability	GCCCACCGACGTAAAAGTATGG	PRTG	ENSG00000166450	-0.047423960486040695	[199,172]	[147,145]	0	hSpCas9	negative selection	4681597
55682477	55682499	15	-	27760321	HL60	viability	GGATAACTGCCCTACCAACAGG	PRTG	ENSG00000166450	0.15390840321252808	[208,213]	[127,261]	2	hSpCas9	negative selection	4681598
55740595	55740617	15	+	27760321	HL60	viability	CCTGGCAATCTAAAACGACTGG	PRTG	ENSG00000166450	0.6088667068293262	[343,293]	[334,460]	7	hSpCas9	negative selection	4681599
55673583	55673605	15	-	27760321	HT1080	viability	TCCCAGCCAAATATCGGCGGGG	PRTG	ENSG00000166450	-0.11179766190813606	[495,386]	[83,248]	0	hSpCas9	negative selection	4765058
55680167	55680189	15	-	27760321	HT1080	viability	ATACTCGGGTACTTGGAAATGG	PRTG	ENSG00000166450	1.436333130200466	[70,55]	[36,102]	7	hSpCas9	negative selection	4765059
55682388	55682410	15	-	27760321	HT1080	viability	GCCCACCGACGTAAAAGTATGG	PRTG	ENSG00000166450	1.0115464230258842	[172,134]	[116,130]	5	hSpCas9	negative selection	4765060
55682477	55682499	15	-	27760321	HT1080	viability	GGATAACTGCCCTACCAACAGG	PRTG	ENSG00000166450	1.458360935984194	[213,166]	[240,172]	7	hSpCas9	negative selection	4765061
55740595	55740617	15	+	27760321	HT1080	viability	CCTGGCAATCTAAAACGACTGG	PRTG	ENSG00000166450	0.43995954399614573	[293,229]	[164,115]	2	hSpCas9	negative selection	4765062
55673583	55673605	15	-	27760321	HT29	viability after 7 days	TCCCAGCCAAATATCGGCGGGG	PRTG	ENSG00000166450	0.581633250532408	[495,386]	[854,874,818]	8	hSpCas9	negative selection	4848521
55680167	55680189	15	-	27760321	HT29	viability after 7 days	ATACTCGGGTACTTGGAAATGG	PRTG	ENSG00000166450	0.38401147518929024	[70,55]	[35,242,32]	6	hSpCas9	negative selection	4848522
55682388	55682410	15	-	27760321	HT29	viability after 7 days	GCCCACCGACGTAAAAGTATGG	PRTG	ENSG00000166450	0.0575475734354316	[172,134]	[134,433,43]	0	hSpCas9	negative selection	4848523
55682477	55682499	15	-	27760321	HT29	viability after 7 days	GGATAACTGCCCTACCAACAGG	PRTG	ENSG00000166450	0.36177502678465656	[213,166]	[415,189,350]	5	hSpCas9	negative selection	4848524
55740595	55740617	15	+	27760321	HT29	viability after 7 days	CCTGGCAATCTAAAACGACTGG	PRTG	ENSG00000166450	-0.36703492287493894	[293,229]	[333,144,312]	-5	hSpCas9	negative selection	4848525
55673583	55673605	15	-	27760321	HT29	viability after 25 days	TCCCAGCCAAATATCGGCGGGG	PRTG	ENSG00000166450	0.8845154789557741	[495,386]	[774,939,1105]	8	hSpCas9	negative selection	4931984
55680167	55680189	15	-	27760321	HT29	viability after 25 days	ATACTCGGGTACTTGGAAATGG	PRTG	ENSG00000166450	-0.3686460820890356	[70,55]	[16,72,83]	-4	hSpCas9	negative selection	4931985
55682388	55682410	15	-	27760321	HT29	viability after 25 days	GCCCACCGACGTAAAAGTATGG	PRTG	ENSG00000166450	0.9713873253637315	[172,134]	[489,384,127]	9	hSpCas9	negative selection	4931986
55682477	55682499	15	-	27760321	HT29	viability after 25 days	GGATAACTGCCCTACCAACAGG	PRTG	ENSG00000166450	0.9334542799230237	[213,166]	[261,383,632]	9	hSpCas9	negative selection	4931987
55740595	55740617	15	+	27760321	HT29	viability after 25 days	CCTGGCAATCTAAAACGACTGG	PRTG	ENSG00000166450	0.17244592586537616	[293,229]	[243,365,415]	1	hSpCas9	negative selection	4931988
55673583	55673605	15	-	27760321	HT29	viability after 22 days	TCCCAGCCAAATATCGGCGGGG	PRTG	ENSG00000166450	0.7885144564947402	[495,386]	[953,1096,588]	8	hSpCas9	negative selection	5015447
55680167	55680189	15	-	27760321	HT29	viability after 22 days	ATACTCGGGTACTTGGAAATGG	PRTG	ENSG00000166450	0.20578913036830304	[70,55]	[25,117,111]	2	hSpCas9	negative selection	5015448
55682388	55682410	15	-	27760321	HT29	viability after 22 days	GCCCACCGACGTAAAAGTATGG	PRTG	ENSG00000166450	0.6308918934412798	[172,134]	[137,391,300]	7	hSpCas9	negative selection	5015449
55682477	55682499	15	-	27760321	HT29	viability after 22 days	GGATAACTGCCCTACCAACAGG	PRTG	ENSG00000166450	0.3172428797461787	[213,166]	[139,285,401]	3	hSpCas9	negative selection	5015450
55740595	55740617	15	+	27760321	HT29	viability after 22 days	CCTGGCAATCTAAAACGACTGG	PRTG	ENSG00000166450	0.3473943660099037	[293,229]	[217,423,519]	3	hSpCas9	negative selection	5015451
55673583	55673605	15	-	27760321	HT29	viability after 19 days	TCCCAGCCAAATATCGGCGGGG	PRTG	ENSG00000166450	0.6505326205736011	[495,386]	[1000,1031,381]	6	hSpCas9	negative selection	5098910
55680167	55680189	15	-	27760321	HT29	viability after 19 days	ATACTCGGGTACTTGGAAATGG	PRTG	ENSG00000166450	0.3275063534520064	[70,55]	[66,166,38]	3	hSpCas9	negative selection	5098911
55682388	55682410	15	-	27760321	HT29	viability after 19 days	GCCCACCGACGTAAAAGTATGG	PRTG	ENSG00000166450	0.31286785536214323	[172,134]	[213,418,29]	3	hSpCas9	negative selection	5098912
55682477	55682499	15	-	27760321	HT29	viability after 19 days	GGATAACTGCCCTACCAACAGG	PRTG	ENSG00000166450	0.07133302959290433	[213,166]	[215,260,208]	0	hSpCas9	negative selection	5098913
55740595	55740617	15	+	27760321	HT29	viability after 19 days	CCTGGCAATCTAAAACGACTGG	PRTG	ENSG00000166450	0.22561947487777995	[293,229]	[386,535,139]	2	hSpCas9	negative selection	5098914
55673583	55673605	15	-	27760321	HT29	viability after 16 days	TCCCAGCCAAATATCGGCGGGG	PRTG	ENSG00000166450	0.5259742375182219	[495,386]	[721,963,441]	6	hSpCas9	negative selection	5182373
55680167	55680189	15	-	27760321	HT29	viability after 16 days	ATACTCGGGTACTTGGAAATGG	PRTG	ENSG00000166450	-0.8061842493550762	[70,55]	[5,66,44]	-6	hSpCas9	negative selection	5182374
55682388	55682410	15	-	27760321	HT29	viability after 16 days	GCCCACCGACGTAAAAGTATGG	PRTG	ENSG00000166450	0.4796783493200676	[172,134]	[348,239,141]	5	hSpCas9	negative selection	5182375
55682477	55682499	15	-	27760321	HT29	viability after 16 days	GGATAACTGCCCTACCAACAGG	PRTG	ENSG00000166450	0.627290409601017	[213,166]	[262,456,257]	7	hSpCas9	negative selection	5182376
55740595	55740617	15	+	27760321	HT29	viability after 16 days	CCTGGCAATCTAAAACGACTGG	PRTG	ENSG00000166450	-0.22049938071428937	[293,229]	[229,127,397]	-2	hSpCas9	negative selection	5182377
55673583	55673605	15	-	27760321	HT29	viability after 13 days	TCCCAGCCAAATATCGGCGGGG	PRTG	ENSG00000166450	0.6009145912898315	[495,386]	[964,658,709]	7	hSpCas9	negative selection	5265836
55680167	55680189	15	-	27760321	HT29	viability after 13 days	ATACTCGGGTACTTGGAAATGG	PRTG	ENSG00000166450	-0.5069275477396364	[70,55]	[18,55,78]	-5	hSpCas9	negative selection	5265837
55682388	55682410	15	-	27760321	HT29	viability after 13 days	GCCCACCGACGTAAAAGTATGG	PRTG	ENSG00000166450	0.2420350659401005	[172,134]	[168,271,193]	3	hSpCas9	negative selection	5265838
55682477	55682499	15	-	27760321	HT29	viability after 13 days	GGATAACTGCCCTACCAACAGG	PRTG	ENSG00000166450	0.7821250133544552	[213,166]	[456,321,361]	8	hSpCas9	negative selection	5265839
55740595	55740617	15	+	27760321	HT29	viability after 13 days	CCTGGCAATCTAAAACGACTGG	PRTG	ENSG00000166450	-0.40137718974861775	[293,229]	[264,188,235]	-5	hSpCas9	negative selection	5265840
55673583	55673605	15	-	27760321	HT29	viability after 10 days	TCCCAGCCAAATATCGGCGGGG	PRTG	ENSG00000166450	0.2480054085894315	[495,386]	[639,545,771]	3	hSpCas9	negative selection	5349299
55680167	55680189	15	-	27760321	HT29	viability after 10 days	ATACTCGGGTACTTGGAAATGG	PRTG	ENSG00000166450	-0.7354336380774393	[70,55]	[26,77,38]	-7	hSpCas9	negative selection	5349300
55682388	55682410	15	-	27760321	HT29	viability after 10 days	GCCCACCGACGTAAAAGTATGG	PRTG	ENSG00000166450	0.29277558324286246	[172,134]	[253,295,159]	4	hSpCas9	negative selection	5349301
55682477	55682499	15	-	27760321	HT29	viability after 10 days	GGATAACTGCCCTACCAACAGG	PRTG	ENSG00000166450	0.5093638635615467	[213,166]	[376,328,309]	7	hSpCas9	negative selection	5349302
55740595	55740617	15	+	27760321	HT29	viability after 10 days	CCTGGCAATCTAAAACGACTGG	PRTG	ENSG00000166450	0.12897850023026486	[293,229]	[323,327,418]	1	hSpCas9	negative selection	5349303
55673583	55673605	15	-	27760321	MOLM13	viability	TCCCAGCCAAATATCGGCGGGG	PRTG	ENSG00000166450	0.33016859830029033	[449,495]	[432,256]	2	hSpCas9	negative selection	5432762
55680167	55680189	15	-	27760321	MOLM13	viability	ATACTCGGGTACTTGGAAATGG	PRTG	ENSG00000166450	-0.37020614080568226	[74,70]	[39,24]	-2	hSpCas9	negative selection	5432763
55682388	55682410	15	-	27760321	MOLM13	viability	GCCCACCGACGTAAAAGTATGG	PRTG	ENSG00000166450	1.509158748481159	[199,172]	[120,449]	9	hSpCas9	negative selection	5432764
55682477	55682499	15	-	27760321	MOLM13	viability	GGATAACTGCCCTACCAACAGG	PRTG	ENSG00000166450	1.4363589142425537	[208,213]	[467,201]	8	hSpCas9	negative selection	5432765
55740595	55740617	15	+	27760321	MOLM13	viability	CCTGGCAATCTAAAACGACTGG	PRTG	ENSG00000166450	0.4461372092758619	[343,293]	[352,151]	3	hSpCas9	negative selection	5432766
55742681	55742704	15	+	27661255	K562	viability	GACAGGCCGCAGGGCGAGAGCGG	PRTG	ENSG00000166450	-0.05921260834087143	[652,869]	[589,572]	-2	dCas9-KRAB	negative selection	5504693
55742873	55742896	15	+	27661255	K562	viability	GCGCGGAGCAGCATCCCCGGCGG	PRTG	ENSG00000166450	-0.09714956918700546	[455,516]	[409,321]	-4	dCas9-KRAB	negative selection	5504694
55742723	55742746	15	-	27661255	K562	viability	GCGCGCGGCGGGGTCCTCCGTGG	PRTG	ENSG00000166450	0.20923906616523413	[211,122]	[153,157]	7	dCas9-KRAB	negative selection	5504695
55742772	55742795	15	-	27661255	K562	viability	GAGCGGGCGCGAGTGGGATGGGG	PRTG	ENSG00000166450	-0.16123520171015407	[695,648]	[595,382]	-5	dCas9-KRAB	negative selection	5504696
55740594	55740617	15	+	27260156	BXPC3	viability	GCCTGGCAATCTAAAACGACTGG	PRTG	ENSG00000166450	0.26716232249542743	[305]	[369,345,394,436]	6	hSpCas9	negative selection	5565072
55683820	55683843	15	+	27260156	BXPC3	viability	AACTCCCATGTTATGACTGCAGG	PRTG	ENSG00000166450	0.09338733568013846	[1052]	[1175,1065,1176,1291]	2	hSpCas9	negative selection	5565073
55740571	55740594	15	-	27260156	BXPC3	viability	TCACGGAGAAGTTCCTATTAAGG	PRTG	ENSG00000166450	0.37089085550134193	[295]	[425,446,365,345]	7	hSpCas9	negative selection	5565074
55683869	55683892	15	+	27260156	BXPC3	viability	ATCGAGCAACTCCACCTTCGTGG	PRTG	ENSG00000166450	-0.06730056632959291	[1020]	[960,967,938,1234]	-1	hSpCas9	negative selection	5629331
55742902	55742925	15	-	27260156	BXPC3	viability	CTCCTCTGCGACCCCTCGCCCGG	PRTG	ENSG00000166450	-0.03349858875747997	[493]	[511,459,503,545]	0	hSpCas9	negative selection	5629332
55742900	55742923	15	+	27260156	BXPC3	viability	AGCCGGGCGAGGGGTCGCAGAGG	PRTG	ENSG00000166450	-1.1636466549750466	[41]	[16,5,17,40]	-9	hSpCas9	negative selection	5629333
55740594	55740617	15	+	27260156	A673	viability	GCCTGGCAATCTAAAACGACTGG	PRTG	ENSG00000166450	0.3743816961141167	[305]	[504,454,516,427]	8	hSpCas9	negative selection	5686323
55683820	55683843	15	+	27260156	A673	viability	AACTCCCATGTTATGACTGCAGG	PRTG	ENSG00000166450	-0.03081860557550553	[1052]	[1276,1157,1446,1060]	0	hSpCas9	negative selection	5686324
55740571	55740594	15	-	27260156	A673	viability	TCACGGAGAAGTTCCTATTAAGG	PRTG	ENSG00000166450	0.0483557437472345	[295]	[453,297,335,394]	1	hSpCas9	negative selection	5686325
55683869	55683892	15	+	27260156	A673	viability	ATCGAGCAACTCCACCTTCGTGG	PRTG	ENSG00000166450	-0.0889134652416248	[1020]	[1175,1119,1145,1170]	-2	hSpCas9	negative selection	5750582
55742902	55742925	15	-	27260156	A673	viability	CTCCTCTGCGACCCCTCGCCCGG	PRTG	ENSG00000166450	-0.006531939610980073	[493]	[753,565,504,553]	0	hSpCas9	negative selection	5750583
55742900	55742923	15	+	27260156	A673	viability	AGCCGGGCGAGGGGTCGCAGAGG	PRTG	ENSG00000166450	-0.42401116084345025	[41]	[31,17,31,69]	-8	hSpCas9	negative selection	5750584
55740594	55740617	15	+	27260156	A375	viability	GCCTGGCAATCTAAAACGACTGG	PRTG	ENSG00000166450	0.27391866896295414	[305]	[397,535,429,382]	4	hSpCas9	negative selection	5807574
55683820	55683843	15	+	27260156	A375	viability	AACTCCCATGTTATGACTGCAGG	PRTG	ENSG00000166450	0.2585642791932563	[1052]	[1595,1615,1498,1219]	4	hSpCas9	negative selection	5807575
55740571	55740594	15	-	27260156	A375	viability	TCACGGAGAAGTTCCTATTAAGG	PRTG	ENSG00000166450	0.7283758485333666	[295]	[580,538,745,434]	9	hSpCas9	negative selection	5807576
55683869	55683892	15	+	27260156	A375	viability	ATCGAGCAACTCCACCTTCGTGG	PRTG	ENSG00000166450	0.33172557489692767	[1020]	[1568,1751,1674,1086]	5	hSpCas9	negative selection	5871833
55742902	55742925	15	-	27260156	A375	viability	CTCCTCTGCGACCCCTCGCCCGG	PRTG	ENSG00000166450	-0.08052729819768968	[493]	[732,562,459,440]	-1	hSpCas9	negative selection	5871834
55742900	55742923	15	+	27260156	A375	viability	AGCCGGGCGAGGGGTCGCAGAGG	PRTG	ENSG00000166450	0.08733364484687733	[41]	[74,127,0,18]	1	hSpCas9	negative selection	5871835
55740594	55740617	15	+	27260156	COLO741	viability	GCCTGGCAATCTAAAACGACTGG	PRTG	ENSG00000166450	0.3980968917102907	[305]	[730,380,454]	7	hSpCas9	negative selection	5928825
55683820	55683843	15	+	27260156	COLO741	viability	AACTCCCATGTTATGACTGCAGG	PRTG	ENSG00000166450	-0.16092281914738948	[1052]	[1228,1153,1224]	-3	hSpCas9	negative selection	5928826
55740571	55740594	15	-	27260156	COLO741	viability	TCACGGAGAAGTTCCTATTAAGG	PRTG	ENSG00000166450	0.5198052730631564	[295]	[701,411,525]	9	hSpCas9	negative selection	5928827
55683869	55683892	15	+	27260156	COLO741	viability	ATCGAGCAACTCCACCTTCGTGG	PRTG	ENSG00000166450	-0.06294730774979618	[1020]	[1368,1251,1140]	-1	hSpCas9	negative selection	5993084
55742902	55742925	15	-	27260156	COLO741	viability	CTCCTCTGCGACCCCTCGCCCGG	PRTG	ENSG00000166450	-0.11707555741017257	[493]	[711,594,457]	-3	hSpCas9	negative selection	5993085
55742900	55742923	15	+	27260156	COLO741	viability	AGCCGGGCGAGGGGTCGCAGAGG	PRTG	ENSG00000166450	-0.4691078879165995	[41]	[39,60,16]	-7	hSpCas9	negative selection	5993086
55740594	55740617	15	+	27260156	CAL120	viability	GCCTGGCAATCTAAAACGACTGG	PRTG	ENSG00000166450	0.7047344370184155	[305]	[673,651,544]	9	hSpCas9	negative selection	6050076
55683820	55683843	15	+	27260156	CAL120	viability	AACTCCCATGTTATGACTGCAGG	PRTG	ENSG00000166450	0.20684744358732354	[1052]	[1445,1655,1425]	3	hSpCas9	negative selection	6050077
55740571	55740594	15	-	27260156	CAL120	viability	TCACGGAGAAGTTCCTATTAAGG	PRTG	ENSG00000166450	0.14832327859180494	[295]	[415,419,389]	2	hSpCas9	negative selection	6050078
55683869	55683892	15	+	27260156	CAL120	viability	ATCGAGCAACTCCACCTTCGTGG	PRTG	ENSG00000166450	0.46994578842375345	[1020]	[2423,1896,1069]	7	hSpCas9	negative selection	6114335
55742902	55742925	15	-	27260156	CAL120	viability	CTCCTCTGCGACCCCTCGCCCGG	PRTG	ENSG00000166450	0.05601376063220677	[493]	[810,615,517]	0	hSpCas9	negative selection	6114336
55742900	55742923	15	+	27260156	CAL120	viability	AGCCGGGCGAGGGGTCGCAGAGG	PRTG	ENSG00000166450	-1.1480575074692467	[41]	[2,60,3]	-9	hSpCas9	negative selection	6114337
55740594	55740617	15	+	27260156	CADOES1	viability	GCCTGGCAATCTAAAACGACTGG	PRTG	ENSG00000166450	0.26222829228713046	[305]	[471,320,254,315]	4	hSpCas9	negative selection	6171327
55683820	55683843	15	+	27260156	CADOES1	viability	AACTCCCATGTTATGACTGCAGG	PRTG	ENSG00000166450	-0.004797084190992784	[1052]	[674,814,1125,1300]	0	hSpCas9	negative selection	6171328
55740571	55740594	15	-	27260156	CADOES1	viability	TCACGGAGAAGTTCCTATTAAGG	PRTG	ENSG00000166450	0.5023197470621232	[295]	[307,414,346,493]	8	hSpCas9	negative selection	6171329
55683869	55683892	15	+	27260156	CADOES1	viability	ATCGAGCAACTCCACCTTCGTGG	PRTG	ENSG00000166450	-0.00041172020855473335	[1020]	[909,973,821,1096]	0	hSpCas9	negative selection	6235586
55742902	55742925	15	-	27260156	CADOES1	viability	CTCCTCTGCGACCCCTCGCCCGG	PRTG	ENSG00000166450	0.004022922940693202	[493]	[412,448,545,433]	0	hSpCas9	negative selection	6235587
55742900	55742923	15	+	27260156	CADOES1	viability	AGCCGGGCGAGGGGTCGCAGAGG	PRTG	ENSG00000166450	0.26984712329459937	[41]	[48,5,118,12]	4	hSpCas9	negative selection	6235588
55740594	55740617	15	+	27260156	EWS502	viability	GCCTGGCAATCTAAAACGACTGG	PRTG	ENSG00000166450	0.8163163393502091	[305]	[819,481,480,461]	9	hSpCas9	negative selection	6292578
55683820	55683843	15	+	27260156	EWS502	viability	AACTCCCATGTTATGACTGCAGG	PRTG	ENSG00000166450	0.11769880048898718	[1052]	[873,1124,1444,1456]	2	hSpCas9	negative selection	6292579
55740571	55740594	15	-	27260156	EWS502	viability	TCACGGAGAAGTTCCTATTAAGG	PRTG	ENSG00000166450	0.3673013528671074	[295]	[283,462,370,517]	6	hSpCas9	negative selection	6292580
55683869	55683892	15	+	27260156	EWS502	viability	ATCGAGCAACTCCACCTTCGTGG	PRTG	ENSG00000166450	-0.10779467720882874	[1020]	[965,991,1039,1018]	-2	hSpCas9	negative selection	6356837
55742902	55742925	15	-	27260156	EWS502	viability	CTCCTCTGCGACCCCTCGCCCGG	PRTG	ENSG00000166450	-0.1337293466078226	[493]	[296,404,617,622]	-2	hSpCas9	negative selection	6356838
55742900	55742923	15	+	27260156	EWS502	viability	AGCCGGGCGAGGGGTCGCAGAGG	PRTG	ENSG00000166450	-1.940282613184503	[41]	[6,8,20,9]	-9	hSpCas9	negative selection	6356839
55740594	55740617	15	+	27260156	EW8	viability	GCCTGGCAATCTAAAACGACTGG	PRTG	ENSG00000166450	0.37188204642167655	[305]	[425,208,258,409]	6	hSpCas9	negative selection	6413829
55683820	55683843	15	+	27260156	EW8	viability	AACTCCCATGTTATGACTGCAGG	PRTG	ENSG00000166450	-0.1456128684964897	[1052]	[884,956,637,639]	-3	hSpCas9	negative selection	6413830
55740571	55740594	15	-	27260156	EW8	viability	TCACGGAGAAGTTCCTATTAAGG	PRTG	ENSG00000166450	-0.0849986520096514	[295]	[223,257,171,258]	-1	hSpCas9	negative selection	6413831
55683869	55683892	15	+	27260156	EW8	viability	ATCGAGCAACTCCACCTTCGTGG	PRTG	ENSG00000166450	-0.013410617185625862	[1020]	[960,846,704,798]	0	hSpCas9	negative selection	6478088
55742902	55742925	15	-	27260156	EW8	viability	CTCCTCTGCGACCCCTCGCCCGG	PRTG	ENSG00000166450	0.46355809295085315	[493]	[595,694,369,581]	8	hSpCas9	negative selection	6478089
55742900	55742923	15	+	27260156	EW8	viability	AGCCGGGCGAGGGGTCGCAGAGG	PRTG	ENSG00000166450	-0.5345336722158489	[41]	[38,32,9,15]	-7	hSpCas9	negative selection	6478090
55740594	55740617	15	+	27260156	CORL105	viability	GCCTGGCAATCTAAAACGACTGG	PRTG	ENSG00000166450	0.6536884456008193	[305]	[529,636,665,434]	9	hSpCas9	negative selection	6535080
55683820	55683843	15	+	27260156	CORL105	viability	AACTCCCATGTTATGACTGCAGG	PRTG	ENSG00000166450	0.07818576802367816	[1052]	[1264,1289,1439,1230]	1	hSpCas9	negative selection	6535081
55740571	55740594	15	-	27260156	CORL105	viability	TCACGGAGAAGTTCCTATTAAGG	PRTG	ENSG00000166450	0.6913292079559441	[295]	[551,602,577,506]	9	hSpCas9	negative selection	6535082
55683869	55683892	15	+	27260156	CORL105	viability	ATCGAGCAACTCCACCTTCGTGG	PRTG	ENSG00000166450	0.0717711026713026	[1020]	[1260,1298,1549,960]	1	hSpCas9	negative selection	6599339
55742902	55742925	15	-	27260156	CORL105	viability	CTCCTCTGCGACCCCTCGCCCGG	PRTG	ENSG00000166450	0.14189747340700676	[493]	[550,813,668,516]	2	hSpCas9	negative selection	6599340
55742900	55742923	15	+	27260156	CORL105	viability	AGCCGGGCGAGGGGTCGCAGAGG	PRTG	ENSG00000166450	-0.8646093659146459	[41]	[45,1,19,39]	-9	hSpCas9	negative selection	6599341
55740594	55740617	15	+	27260156	HS294T	viability	GCCTGGCAATCTAAAACGACTGG	PRTG	ENSG00000166450	1.0726868225294612	[305]	[119,234,136,568]	9	hSpCas9	negative selection	6656331
55683820	55683843	15	+	27260156	HS294T	viability	AACTCCCATGTTATGACTGCAGG	PRTG	ENSG00000166450	0.4546034196735571	[1052]	[480,623,582,544]	6	hSpCas9	negative selection	6656332
55740571	55740594	15	-	27260156	HS294T	viability	TCACGGAGAAGTTCCTATTAAGG	PRTG	ENSG00000166450	0.4266052991135534	[295]	[140,121,140,224]	6	hSpCas9	negative selection	6656333
55683869	55683892	15	+	27260156	HS294T	viability	ATCGAGCAACTCCACCTTCGTGG	PRTG	ENSG00000166450	0.35982578421430444	[1020]	[359,570,387,759]	5	hSpCas9	negative selection	6720590
55742902	55742925	15	-	27260156	HS294T	viability	CTCCTCTGCGACCCCTCGCCCGG	PRTG	ENSG00000166450	-0.07217079593374791	[493]	[156,164,205,204]	-1	hSpCas9	negative selection	6720591
55742900	55742923	15	+	27260156	HS294T	viability	AGCCGGGCGAGGGGTCGCAGAGG	PRTG	ENSG00000166450	-1.5907024958776788	[41]	[2,1,10,5]	-9	hSpCas9	negative selection	6720592
55740594	55740617	15	+	27260156	HCC44	viability	GCCTGGCAATCTAAAACGACTGG	PRTG	ENSG00000166450	-0.035871452596713205	[305]	[376,271,360,353]	0	hSpCas9	negative selection	6777582
55683820	55683843	15	+	27260156	HCC44	viability	AACTCCCATGTTATGACTGCAGG	PRTG	ENSG00000166450	0.027697962905124607	[1052]	[1277,813,1492,1366]	0	hSpCas9	negative selection	6777583
55740571	55740594	15	-	27260156	HCC44	viability	TCACGGAGAAGTTCCTATTAAGG	PRTG	ENSG00000166450	0.4612433863964256	[295]	[392,435,659,384]	7	hSpCas9	negative selection	6777584
55683869	55683892	15	+	27260156	HCC44	viability	ATCGAGCAACTCCACCTTCGTGG	PRTG	ENSG00000166450	-0.28167764093756076	[1020]	[812,1050,1100,829]	-4	hSpCas9	negative selection	6841841
55742902	55742925	15	-	27260156	HCC44	viability	CTCCTCTGCGACCCCTCGCCCGG	PRTG	ENSG00000166450	-0.07138870191501957	[493]	[373,435,532,770]	-1	hSpCas9	negative selection	6841842
55742900	55742923	15	+	27260156	HCC44	viability	AGCCGGGCGAGGGGTCGCAGAGG	PRTG	ENSG00000166450	-1.1472654304061214	[41]	[0,19,29,33]	-9	hSpCas9	negative selection	6841843
55740594	55740617	15	+	27260156	G402	viability	GCCTGGCAATCTAAAACGACTGG	PRTG	ENSG00000166450	0.5542897552958881	[305]	[298,798,446,620]	7	hSpCas9	negative selection	6898833
55683820	55683843	15	+	27260156	G402	viability	AACTCCCATGTTATGACTGCAGG	PRTG	ENSG00000166450	-0.029161579829339868	[1052]	[1488,1131,1080,1350]	0	hSpCas9	negative selection	6898834
55740571	55740594	15	-	27260156	G402	viability	TCACGGAGAAGTTCCTATTAAGG	PRTG	ENSG00000166450	0.5117282680623546	[295]	[836,405,530,332]	6	hSpCas9	negative selection	6898835
55683869	55683892	15	+	27260156	G402	viability	ATCGAGCAACTCCACCTTCGTGG	PRTG	ENSG00000166450	0.5338820113846361	[1020]	[2784,1208,1812,1521]	6	hSpCas9	negative selection	6963092
55742902	55742925	15	-	27260156	G402	viability	CTCCTCTGCGACCCCTCGCCCGG	PRTG	ENSG00000166450	0.21035594344286312	[493]	[506,361,772,1078]	2	hSpCas9	negative selection	6963093
55742900	55742923	15	+	27260156	G402	viability	AGCCGGGCGAGGGGTCGCAGAGG	PRTG	ENSG00000166450	-0.5499352686027317	[41]	[13,26,30,62]	-6	hSpCas9	negative selection	6963094
55740594	55740617	15	+	27260156	L33	viability	GCCTGGCAATCTAAAACGACTGG	PRTG	ENSG00000166450	0.15929078386517537	[305]	[329,107,238,392]	3	hSpCas9	negative selection	7020084
55683820	55683843	15	+	27260156	L33	viability	AACTCCCATGTTATGACTGCAGG	PRTG	ENSG00000166450	0.03452461601204715	[1052]	[1040,456,659,1107]	0	hSpCas9	negative selection	7020085
55740571	55740594	15	-	27260156	L33	viability	TCACGGAGAAGTTCCTATTAAGG	PRTG	ENSG00000166450	0.3042401105293606	[295]	[354,122,256,397]	6	hSpCas9	negative selection	7020086
55683869	55683892	15	+	27260156	L33	viability	ATCGAGCAACTCCACCTTCGTGG	PRTG	ENSG00000166450	-0.08530841709743986	[1020]	[1014,362,515,1123]	-2	hSpCas9	negative selection	7084343
55742902	55742925	15	-	27260156	L33	viability	CTCCTCTGCGACCCCTCGCCCGG	PRTG	ENSG00000166450	0.17926088395654866	[493]	[528,229,329,621]	4	hSpCas9	negative selection	7084344
55742900	55742923	15	+	27260156	L33	viability	AGCCGGGCGAGGGGTCGCAGAGG	PRTG	ENSG00000166450	-0.6296865486891647	[41]	[25,12,14,26]	-9	hSpCas9	negative selection	7084345
55740594	55740617	15	+	27260156	K562	viability	GCCTGGCAATCTAAAACGACTGG	PRTG	ENSG00000166450	0.6267356371931296	[305]	[283,1017,155,256]	7	hSpCas9	negative selection	7141335
55683820	55683843	15	+	27260156	K562	viability	AACTCCCATGTTATGACTGCAGG	PRTG	ENSG00000166450	-0.2754878139393866	[1052]	[883,1106,597,548]	-3	hSpCas9	negative selection	7141336
55740571	55740594	15	-	27260156	K562	viability	TCACGGAGAAGTTCCTATTAAGG	PRTG	ENSG00000166450	-0.14823546003752852	[295]	[150,179,358,245]	-2	hSpCas9	negative selection	7141337
55683869	55683892	15	+	27260156	K562	viability	ATCGAGCAACTCCACCTTCGTGG	PRTG	ENSG00000166450	0.02332599844712613	[1020]	[963,1067,759,900]	0	hSpCas9	negative selection	7205594
55742902	55742925	15	-	27260156	K562	viability	CTCCTCTGCGACCCCTCGCCCGG	PRTG	ENSG00000166450	0.30310858938257756	[493]	[234,583,1028,316]	4	hSpCas9	negative selection	7205595
55742900	55742923	15	+	27260156	K562	viability	AGCCGGGCGAGGGGTCGCAGAGG	PRTG	ENSG00000166450	-0.8114906059441447	[41]	[0,0,0,72]	-7	hSpCas9	negative selection	7205596
55740594	55740617	15	+	27260156	HT29	viability	GCCTGGCAATCTAAAACGACTGG	PRTG	ENSG00000166450	0.25704481381190464	[305]	[491,591,368,349]	5	hSpCas9	negative selection	7262586
55683820	55683843	15	+	27260156	HT29	viability	AACTCCCATGTTATGACTGCAGG	PRTG	ENSG00000166450	-0.07194301255947355	[1052]	[1357,1418,1036,1091]	-1	hSpCas9	negative selection	7262587
55740571	55740594	15	-	27260156	HT29	viability	TCACGGAGAAGTTCCTATTAAGG	PRTG	ENSG00000166450	0.21854794485187534	[295]	[444,637,356,270]	4	hSpCas9	negative selection	7262588
55683869	55683892	15	+	27260156	HT29	viability	ATCGAGCAACTCCACCTTCGTGG	PRTG	ENSG00000166450	-0.07505139178167153	[1020]	[1503,1073,924,1212]	-1	hSpCas9	negative selection	7326845
55742902	55742925	15	-	27260156	HT29	viability	CTCCTCTGCGACCCCTCGCCCGG	PRTG	ENSG00000166450	0.019764741329762206	[493]	[695,729,584,455]	0	hSpCas9	negative selection	7326846
55742900	55742923	15	+	27260156	HT29	viability	AGCCGGGCGAGGGGTCGCAGAGG	PRTG	ENSG00000166450	-0.5009879896228759	[41]	[1,11,94,30]	-7	hSpCas9	negative selection	7326847
55740594	55740617	15	+	27260156	MHHES1	viability	GCCTGGCAATCTAAAACGACTGG	PRTG	ENSG00000166450	-0.07391775236923015	[305]	[379,290,449,211]	-1	hSpCas9	negative selection	7383837
55683820	55683843	15	+	27260156	MHHES1	viability	AACTCCCATGTTATGACTGCAGG	PRTG	ENSG00000166450	-0.04884190469532124	[1052]	[1300,1047,1474,822]	-1	hSpCas9	negative selection	7383838
55740571	55740594	15	-	27260156	MHHES1	viability	TCACGGAGAAGTTCCTATTAAGG	PRTG	ENSG00000166450	0.21315480502718764	[295]	[583,494,332,202]	4	hSpCas9	negative selection	7383839
55683869	55683892	15	+	27260156	MHHES1	viability	ATCGAGCAACTCCACCTTCGTGG	PRTG	ENSG00000166450	0.07092501805459084	[1020]	[1253,1134,1308,1123]	1	hSpCas9	negative selection	7448096
55742902	55742925	15	-	27260156	MHHES1	viability	CTCCTCTGCGACCCCTCGCCCGG	PRTG	ENSG00000166450	0.04769854983588903	[493]	[590,768,320,615]	0	hSpCas9	negative selection	7448097
55742900	55742923	15	+	27260156	MHHES1	viability	AGCCGGGCGAGGGGTCGCAGAGG	PRTG	ENSG00000166450	-0.9320473806541631	[41]	[1,27,29,33]	-9	hSpCas9	negative selection	7448098
55740594	55740617	15	+	27260156	MEWO	viability	GCCTGGCAATCTAAAACGACTGG	PRTG	ENSG00000166450	0.0687657378866231	[305]	[408,253,258]	1	hSpCas9	negative selection	7505088
55683820	55683843	15	+	27260156	MEWO	viability	AACTCCCATGTTATGACTGCAGG	PRTG	ENSG00000166450	-0.10644902667511058	[1052]	[1010,833,918]	-2	hSpCas9	negative selection	7505089
55740571	55740594	15	-	27260156	MEWO	viability	TCACGGAGAAGTTCCTATTAAGG	PRTG	ENSG00000166450	0.49143017355580765	[295]	[451,388,338]	8	hSpCas9	negative selection	7505090
55683869	55683892	15	+	27260156	MEWO	viability	ATCGAGCAACTCCACCTTCGTGG	PRTG	ENSG00000166450	-0.03991467306957586	[1020]	[1045,900,862]	-1	hSpCas9	negative selection	7569347
55742902	55742925	15	-	27260156	MEWO	viability	CTCCTCTGCGACCCCTCGCCCGG	PRTG	ENSG00000166450	0.11761329890191745	[493]	[451,620,420]	2	hSpCas9	negative selection	7569348
55742900	55742923	15	+	27260156	MEWO	viability	AGCCGGGCGAGGGGTCGCAGAGG	PRTG	ENSG00000166450	-0.3162824535337294	[41]	[73,8,19]	-6	hSpCas9	negative selection	7569349
55740594	55740617	15	+	27260156	LNCAPCLONEFGC	viability	GCCTGGCAATCTAAAACGACTGG	PRTG	ENSG00000166450	0.4958183210160948	[305]	[420,227,596,357]	7	hSpCas9	negative selection	7626339
55683820	55683843	15	+	27260156	LNCAPCLONEFGC	viability	AACTCCCATGTTATGACTGCAGG	PRTG	ENSG00000166450	-0.037309948472431964	[1052]	[915,869,985,957]	0	hSpCas9	negative selection	7626340
55740571	55740594	15	-	27260156	LNCAPCLONEFGC	viability	TCACGGAGAAGTTCCTATTAAGG	PRTG	ENSG00000166450	0.1686048880203831	[295]	[255,296,304,348]	2	hSpCas9	negative selection	7626341
55683869	55683892	15	+	27260156	LNCAPCLONEFGC	viability	ATCGAGCAACTCCACCTTCGTGG	PRTG	ENSG00000166450	0.05355736906188735	[1020]	[726,846,1540,821]	0	hSpCas9	negative selection	7690598
55742902	55742925	15	-	27260156	LNCAPCLONEFGC	viability	CTCCTCTGCGACCCCTCGCCCGG	PRTG	ENSG00000166450	0.13599446087296257	[493]	[433,417,561,568]	2	hSpCas9	negative selection	7690599
55742900	55742923	15	+	27260156	LNCAPCLONEFGC	viability	AGCCGGGCGAGGGGTCGCAGAGG	PRTG	ENSG00000166450	-0.08710174463780085	[41]	[38,25,9,64]	-1	hSpCas9	negative selection	7690600
55740594	55740617	15	+	27260156	PANC0327	viability	GCCTGGCAATCTAAAACGACTGG	PRTG	ENSG00000166450	0.5277040675342348	[305]	[398,352,420,399]	7	hSpCas9	negative selection	7747590
55683820	55683843	15	+	27260156	PANC0327	viability	AACTCCCATGTTATGACTGCAGG	PRTG	ENSG00000166450	0.18637170836893002	[1052]	[1403,926,1117,853]	2	hSpCas9	negative selection	7747591
55740571	55740594	15	-	27260156	PANC0327	viability	TCACGGAGAAGTTCCTATTAAGG	PRTG	ENSG00000166450	-0.03127538930595075	[295]	[390,233,189,227]	0	hSpCas9	negative selection	7747592
55683869	55683892	15	+	27260156	PANC0327	viability	ATCGAGCAACTCCACCTTCGTGG	PRTG	ENSG00000166450	0.1502273588809795	[1020]	[916,1132,983,967]	2	hSpCas9	negative selection	7811849
55742902	55742925	15	-	27260156	PANC0327	viability	CTCCTCTGCGACCCCTCGCCCGG	PRTG	ENSG00000166450	-0.0855345146214749	[493]	[329,514,325,462]	-1	hSpCas9	negative selection	7811850
55742900	55742923	15	+	27260156	PANC0327	viability	AGCCGGGCGAGGGGTCGCAGAGG	PRTG	ENSG00000166450	-1.0607606847368816	[41]	[65,5,2,1]	-8	hSpCas9	negative selection	7811851
55740594	55740617	15	+	27260156	NCIH2009	viability	GCCTGGCAATCTAAAACGACTGG	PRTG	ENSG00000166450	0.15382720665474892	[305]	[482,505,437]	2	hSpCas9	negative selection	7868841
55683820	55683843	15	+	27260156	NCIH2009	viability	AACTCCCATGTTATGACTGCAGG	PRTG	ENSG00000166450	0.03736526818741526	[1052]	[1813,1508,1263]	0	hSpCas9	negative selection	7868842
55740571	55740594	15	-	27260156	NCIH2009	viability	TCACGGAGAAGTTCCTATTAAGG	PRTG	ENSG00000166450	0.33948794596363446	[295]	[479,599,478]	4	hSpCas9	negative selection	7868843
55683869	55683892	15	+	27260156	NCIH2009	viability	ATCGAGCAACTCCACCTTCGTGG	PRTG	ENSG00000166450	0.06041164530864962	[1020]	[2039,1331,1199]	0	hSpCas9	negative selection	7933100
55742902	55742925	15	-	27260156	NCIH2009	viability	CTCCTCTGCGACCCCTCGCCCGG	PRTG	ENSG00000166450	0.42515865071473014	[493]	[1168,1010,644]	6	hSpCas9	negative selection	7933101
55742900	55742923	15	+	27260156	NCIH2009	viability	AGCCGGGCGAGGGGTCGCAGAGG	PRTG	ENSG00000166450	-3.8038174025227294	[41]	[10,0,1]	-9	hSpCas9	negative selection	7933102
55740594	55740617	15	+	27260156	NCIH1373	viability	GCCTGGCAATCTAAAACGACTGG	PRTG	ENSG00000166450	0.49009972708177224	[305]	[515,413,599,104]	5	hSpCas9	negative selection	7990092
55683820	55683843	15	+	27260156	NCIH1373	viability	AACTCCCATGTTATGACTGCAGG	PRTG	ENSG00000166450	0.44846019394639636	[1052]	[2150,1631,1545,304]	4	hSpCas9	negative selection	7990093
55740571	55740594	15	-	27260156	NCIH1373	viability	TCACGGAGAAGTTCCTATTAAGG	PRTG	ENSG00000166450	0.623515922811668	[295]	[542,578,244,180]	6	hSpCas9	negative selection	7990094
55683869	55683892	15	+	27260156	NCIH1373	viability	ATCGAGCAACTCCACCTTCGTGG	PRTG	ENSG00000166450	0.5639910211327761	[1020]	[1960,1578,1906,351]	5	hSpCas9	negative selection	8054351
55742902	55742925	15	-	27260156	NCIH1373	viability	CTCCTCTGCGACCCCTCGCCCGG	PRTG	ENSG00000166450	0.43458692571034885	[493]	[550,713,750,251]	4	hSpCas9	negative selection	8054352
55742900	55742923	15	+	27260156	NCIH1373	viability	AGCCGGGCGAGGGGTCGCAGAGG	PRTG	ENSG00000166450	-2.933291867389059	[41]	[0,2,1,4]	-9	hSpCas9	negative selection	8054353
55740594	55740617	15	+	27260156	PATU8902	viability	GCCTGGCAATCTAAAACGACTGG	PRTG	ENSG00000166450	0.9314191397774628	[305]	[1352,792,484,674]	8	hSpCas9	negative selection	8111343
55683820	55683843	15	+	27260156	PATU8902	viability	AACTCCCATGTTATGACTGCAGG	PRTG	ENSG00000166450	-0.11979154732242137	[1052]	[1253,1654,1034,1551]	-1	hSpCas9	negative selection	8111344
55740571	55740594	15	-	27260156	PATU8902	viability	TCACGGAGAAGTTCCTATTAAGG	PRTG	ENSG00000166450	0.7158710127549878	[295]	[396,696,729,894]	7	hSpCas9	negative selection	8111345
55683869	55683892	15	+	27260156	PATU8902	viability	ATCGAGCAACTCCACCTTCGTGG	PRTG	ENSG00000166450	0.2422966073294992	[1020]	[1749,1889,1089,2199]	2	hSpCas9	negative selection	8175602
55742902	55742925	15	-	27260156	PATU8902	viability	CTCCTCTGCGACCCCTCGCCCGG	PRTG	ENSG00000166450	0.23744257571391475	[493]	[847,906,619,925]	2	hSpCas9	negative selection	8175603
55742900	55742923	15	+	27260156	PATU8902	viability	AGCCGGGCGAGGGGTCGCAGAGG	PRTG	ENSG00000166450	-4.896003615433884	[41]	[0,4,0,0]	-9	hSpCas9	negative selection	8175604
55740594	55740617	15	+	27260156	PANC1	viability	GCCTGGCAATCTAAAACGACTGG	PRTG	ENSG00000166450	0.33962145874072375	[305]	[411,324,318,274]	5	hSpCas9	negative selection	8232594
55683820	55683843	15	+	27260156	PANC1	viability	AACTCCCATGTTATGACTGCAGG	PRTG	ENSG00000166450	-0.037690519178625426	[1052]	[957,824,1142,616]	0	hSpCas9	negative selection	8232595
55740571	55740594	15	-	27260156	PANC1	viability	TCACGGAGAAGTTCCTATTAAGG	PRTG	ENSG00000166450	0.3341954944401405	[295]	[302,385,325,281]	5	hSpCas9	negative selection	8232596
55683869	55683892	15	+	27260156	PANC1	viability	ATCGAGCAACTCCACCTTCGTGG	PRTG	ENSG00000166450	-0.031889137447239646	[1020]	[920,1180,711,693]	0	hSpCas9	negative selection	8296853
55742902	55742925	15	-	27260156	PANC1	viability	CTCCTCTGCGACCCCTCGCCCGG	PRTG	ENSG00000166450	0.10417789673311163	[493]	[475,521,506,343]	1	hSpCas9	negative selection	8296854
55742900	55742923	15	+	27260156	PANC1	viability	AGCCGGGCGAGGGGTCGCAGAGG	PRTG	ENSG00000166450	-0.4199988277012108	[41]	[29,45,33,4]	-6	hSpCas9	negative selection	8296855
55740594	55740617	15	+	27260156	PANC0813	viability	GCCTGGCAATCTAAAACGACTGG	PRTG	ENSG00000166450	0.13327325812876578	[305]	[502,431,262,387]	2	hSpCas9	negative selection	8353845
55683820	55683843	15	+	27260156	PANC0813	viability	AACTCCCATGTTATGACTGCAGG	PRTG	ENSG00000166450	0.2701825607775856	[1052]	[1660,1729,1511,1098]	4	hSpCas9	negative selection	8353846
55740571	55740594	15	-	27260156	PANC0813	viability	TCACGGAGAAGTTCCTATTAAGG	PRTG	ENSG00000166450	0.3886903692829415	[295]	[439,341,524,508]	6	hSpCas9	negative selection	8353847
55683869	55683892	15	+	27260156	PANC0813	viability	ATCGAGCAACTCCACCTTCGTGG	PRTG	ENSG00000166450	0.019365782943973286	[1020]	[1358,1303,1024,1185]	0	hSpCas9	negative selection	8418104
55742902	55742925	15	-	27260156	PANC0813	viability	CTCCTCTGCGACCCCTCGCCCGG	PRTG	ENSG00000166450	0.316157023833418	[493]	[834,630,727,705]	5	hSpCas9	negative selection	8418105
55742900	55742923	15	+	27260156	PANC0813	viability	AGCCGGGCGAGGGGTCGCAGAGG	PRTG	ENSG00000166450	-1.46859680601142	[41]	[6,38,19,4]	-9	hSpCas9	negative selection	8418106
55740594	55740617	15	+	27260156	RDES	viability	GCCTGGCAATCTAAAACGACTGG	PRTG	ENSG00000166450	0.5406280260830771	[305]	[396,608,409,647]	8	hSpCas9	negative selection	8475096
55683820	55683843	15	+	27260156	RDES	viability	AACTCCCATGTTATGACTGCAGG	PRTG	ENSG00000166450	0.10473034834147765	[1052]	[1293,1188,1402,1292]	1	hSpCas9	negative selection	8475097
55740571	55740594	15	-	27260156	RDES	viability	TCACGGAGAAGTTCCTATTAAGG	PRTG	ENSG00000166450	0.25334450501601063	[295]	[234,458,457,509]	4	hSpCas9	negative selection	8475098
55683869	55683892	15	+	27260156	RDES	viability	ATCGAGCAACTCCACCTTCGTGG	PRTG	ENSG00000166450	0.12029081568893196	[1020]	[937,1335,1281,1633]	2	hSpCas9	negative selection	8539355
55742902	55742925	15	-	27260156	RDES	viability	CTCCTCTGCGACCCCTCGCCCGG	PRTG	ENSG00000166450	0.007131789858175364	[493]	[519,514,633,622]	0	hSpCas9	negative selection	8539356
55742900	55742923	15	+	27260156	RDES	viability	AGCCGGGCGAGGGGTCGCAGAGG	PRTG	ENSG00000166450	-0.8494720367933999	[41]	[24,13,10,62]	-8	hSpCas9	negative selection	8539357
55740594	55740617	15	+	27260156	PC3	viability	GCCTGGCAATCTAAAACGACTGG	PRTG	ENSG00000166450	0.3257160080988314	[305]	[240,303,655,467]	7	hSpCas9	negative selection	8596347
55683820	55683843	15	+	27260156	PC3	viability	AACTCCCATGTTATGACTGCAGG	PRTG	ENSG00000166450	0.19384544433821205	[1052]	[855,1015,2202,1146]	4	hSpCas9	negative selection	8596348
55740571	55740594	15	-	27260156	PC3	viability	TCACGGAGAAGTTCCTATTAAGG	PRTG	ENSG00000166450	0.38453372404476377	[295]	[236,337,677,434]	7	hSpCas9	negative selection	8596349
55683869	55683892	15	+	27260156	PC3	viability	ATCGAGCAACTCCACCTTCGTGG	PRTG	ENSG00000166450	-0.12214609443674695	[1020]	[728,843,1413,923]	-3	hSpCas9	negative selection	8660606
55742902	55742925	15	-	27260156	PC3	viability	CTCCTCTGCGACCCCTCGCCCGG	PRTG	ENSG00000166450	0.12165495231466252	[493]	[359,547,914,485]	2	hSpCas9	negative selection	8660607
55742900	55742923	15	+	27260156	PC3	viability	AGCCGGGCGAGGGGTCGCAGAGG	PRTG	ENSG00000166450	-0.5338961753335676	[41]	[46,7,26,18]	-8	hSpCas9	negative selection	8660608
55740594	55740617	15	+	27260156	PATU8988T	viability	GCCTGGCAATCTAAAACGACTGG	PRTG	ENSG00000166450	0.7037730279683353	[305]	[511,597,406,415]	9	hSpCas9	negative selection	8717598
55683820	55683843	15	+	27260156	PATU8988T	viability	AACTCCCATGTTATGACTGCAGG	PRTG	ENSG00000166450	-0.3028845890976746	[1052]	[593,1045,809,873]	-5	hSpCas9	negative selection	8717599
55740571	55740594	15	-	27260156	PATU8988T	viability	TCACGGAGAAGTTCCTATTAAGG	PRTG	ENSG00000166450	0.08416614499517927	[295]	[413,282,320,182]	1	hSpCas9	negative selection	8717600
55683869	55683892	15	+	27260156	PATU8988T	viability	ATCGAGCAACTCCACCTTCGTGG	PRTG	ENSG00000166450	-0.12108388207251686	[1020]	[1166,1073,645,747]	-2	hSpCas9	negative selection	8781857
55742902	55742925	15	-	27260156	PATU8988T	viability	CTCCTCTGCGACCCCTCGCCCGG	PRTG	ENSG00000166450	-0.09027386762048518	[493]	[437,620,388,354]	-1	hSpCas9	negative selection	8781858
55742900	55742923	15	+	27260156	PATU8988T	viability	AGCCGGGCGAGGGGTCGCAGAGG	PRTG	ENSG00000166450	-1.343112097870189	[41]	[13,36,0,13]	-9	hSpCas9	negative selection	8781859
55740594	55740617	15	+	27260156	T47D	viability	GCCTGGCAATCTAAAACGACTGG	PRTG	ENSG00000166450	0.49404639149537344	[305]	[584,478,472,472]	8	hSpCas9	negative selection	8838849
55683820	55683843	15	+	27260156	T47D	viability	AACTCCCATGTTATGACTGCAGG	PRTG	ENSG00000166450	0.06511767997600004	[1052]	[1339,1203,1245,1352]	1	hSpCas9	negative selection	8838850
55740571	55740594	15	-	27260156	T47D	viability	TCACGGAGAAGTTCCTATTAAGG	PRTG	ENSG00000166450	0.3329293270106962	[295]	[438,388,386,529]	7	hSpCas9	negative selection	8838851
55683869	55683892	15	+	27260156	T47D	viability	ATCGAGCAACTCCACCTTCGTGG	PRTG	ENSG00000166450	0.09116628055083598	[1020]	[1130,1243,1356,1337]	2	hSpCas9	negative selection	8903108
55742902	55742925	15	-	27260156	T47D	viability	CTCCTCTGCGACCCCTCGCCCGG	PRTG	ENSG00000166450	-0.18248146345914973	[493]	[573,433,494,532]	-4	hSpCas9	negative selection	8903109
55742900	55742923	15	+	27260156	T47D	viability	AGCCGGGCGAGGGGTCGCAGAGG	PRTG	ENSG00000166450	-0.7667331793970824	[41]	[46,26,22,17]	-9	hSpCas9	negative selection	8903110
55740594	55740617	15	+	27260156	SU8686	viability	GCCTGGCAATCTAAAACGACTGG	PRTG	ENSG00000166450	0.4596020189445228	[305]	[276,381,427,634]	7	hSpCas9	negative selection	8960100
55683820	55683843	15	+	27260156	SU8686	viability	AACTCCCATGTTATGACTGCAGG	PRTG	ENSG00000166450	0.15700361501627413	[1052]	[1157,980,1378,1158]	2	hSpCas9	negative selection	8960101
55740571	55740594	15	-	27260156	SU8686	viability	TCACGGAGAAGTTCCTATTAAGG	PRTG	ENSG00000166450	0.5242358395455919	[295]	[391,365,396,562]	8	hSpCas9	negative selection	8960102
55683869	55683892	15	+	27260156	SU8686	viability	ATCGAGCAACTCCACCTTCGTGG	PRTG	ENSG00000166450	0.020439716399809127	[1020]	[1010,1091,888,1109]	0	hSpCas9	negative selection	9024359
55742902	55742925	15	-	27260156	SU8686	viability	CTCCTCTGCGACCCCTCGCCCGG	PRTG	ENSG00000166450	0.05746112596529758	[493]	[513,417,563,559]	1	hSpCas9	negative selection	9024360
55742900	55742923	15	+	27260156	SU8686	viability	AGCCGGGCGAGGGGTCGCAGAGG	PRTG	ENSG00000166450	-0.5140595805661121	[41]	[38,10,0,72]	-7	hSpCas9	negative selection	9024361
55740594	55740617	15	+	27260156	SKES1	viability	GCCTGGCAATCTAAAACGACTGG	PRTG	ENSG00000166450	0.49000925602995404	[305]	[458,501,370,395]	8	hSpCas9	negative selection	9081351
55683820	55683843	15	+	27260156	SKES1	viability	AACTCCCATGTTATGACTGCAGG	PRTG	ENSG00000166450	0.01081925859199706	[1052]	[1312,1137,918,915]	0	hSpCas9	negative selection	9081352
55740571	55740594	15	-	27260156	SKES1	viability	TCACGGAGAAGTTCCTATTAAGG	PRTG	ENSG00000166450	-0.04790237941898823	[295]	[177,411,284,266]	-1	hSpCas9	negative selection	9081353
55683869	55683892	15	+	27260156	SKES1	viability	ATCGAGCAACTCCACCTTCGTGG	PRTG	ENSG00000166450	-0.19055896974619912	[1020]	[970,1014,923,698]	-4	hSpCas9	negative selection	9145610
55742902	55742925	15	-	27260156	SKES1	viability	CTCCTCTGCGACCCCTCGCCCGG	PRTG	ENSG00000166450	0.08483531770839207	[493]	[576,601,623,321]	1	hSpCas9	negative selection	9145611
55742900	55742923	15	+	27260156	SKES1	viability	AGCCGGGCGAGGGGTCGCAGAGG	PRTG	ENSG00000166450	-0.38282305749833156	[41]	[18,31,40,33]	-7	hSpCas9	negative selection	9145612
55740594	55740617	15	+	27260156	TOV112D	viability	GCCTGGCAATCTAAAACGACTGG	PRTG	ENSG00000166450	0.6983281681213569	[305]	[594,475,555,367]	9	hSpCas9	negative selection	9202602
55683820	55683843	15	+	27260156	TOV112D	viability	AACTCCCATGTTATGACTGCAGG	PRTG	ENSG00000166450	0.07371376325448664	[1052]	[1343,1133,930,1055]	1	hSpCas9	negative selection	9202603
55740571	55740594	15	-	27260156	TOV112D	viability	TCACGGAGAAGTTCCTATTAAGG	PRTG	ENSG00000166450	0.1201013137305531	[295]	[387,237,394,253]	2	hSpCas9	negative selection	9202604
55683869	55683892	15	+	27260156	TOV112D	viability	ATCGAGCAACTCCACCTTCGTGG	PRTG	ENSG00000166450	0.07412961085302117	[1020]	[1427,981,803,1095]	1	hSpCas9	negative selection	9266861
55742902	55742925	15	-	27260156	TOV112D	viability	CTCCTCTGCGACCCCTCGCCCGG	PRTG	ENSG00000166450	-0.3106121410012273	[493]	[475,395,444,286]	-6	hSpCas9	negative selection	9266862
55742900	55742923	15	+	27260156	TOV112D	viability	AGCCGGGCGAGGGGTCGCAGAGG	PRTG	ENSG00000166450	-1.3915991609362708	[41]	[9,22,4,26]	-9	hSpCas9	negative selection	9266863
55740594	55740617	15	+	27260156	TC71	viability	GCCTGGCAATCTAAAACGACTGG	PRTG	ENSG00000166450	0.2599524028257402	[305]	[377,422,366,404]	6	hSpCas9	negative selection	9323853
55683820	55683843	15	+	27260156	TC71	viability	AACTCCCATGTTATGACTGCAGG	PRTG	ENSG00000166450	-0.060626565401327825	[1052]	[1080,1046,1027,1180]	-1	hSpCas9	negative selection	9323854
55740571	55740594	15	-	27260156	TC71	viability	TCACGGAGAAGTTCCTATTAAGG	PRTG	ENSG00000166450	0.3422673998446515	[295]	[431,449,383,338]	7	hSpCas9	negative selection	9323855
55683869	55683892	15	+	27260156	TC71	viability	ATCGAGCAACTCCACCTTCGTGG	PRTG	ENSG00000166450	-0.07981407020791553	[1020]	[1121,1053,1036,919]	-2	hSpCas9	negative selection	9388112
55742902	55742925	15	-	27260156	TC71	viability	CTCCTCTGCGACCCCTCGCCCGG	PRTG	ENSG00000166450	-0.09948720854627419	[493]	[503,463,494,514]	-3	hSpCas9	negative selection	9388113
55742900	55742923	15	+	27260156	TC71	viability	AGCCGGGCGAGGGGTCGCAGAGG	PRTG	ENSG00000166450	-0.34859074778058385	[41]	[33,31,42,31]	-7	hSpCas9	negative selection	9388114
55740594	55740617	15	+	27260156	TC32	viability	GCCTGGCAATCTAAAACGACTGG	PRTG	ENSG00000166450	0.4713483056663055	[305]	[358,285,473,519]	7	hSpCas9	negative selection	9445104
55683820	55683843	15	+	27260156	TC32	viability	AACTCCCATGTTATGACTGCAGG	PRTG	ENSG00000166450	0.28498812259686823	[1052]	[1094,1004,1678,1137]	5	hSpCas9	negative selection	9445105
55740571	55740594	15	-	27260156	TC32	viability	TCACGGAGAAGTTCCTATTAAGG	PRTG	ENSG00000166450	0.3650818882803857	[295]	[240,334,434,441]	6	hSpCas9	negative selection	9445106
55683869	55683892	15	+	27260156	TC32	viability	ATCGAGCAACTCCACCTTCGTGG	PRTG	ENSG00000166450	0.07511781109149984	[1020]	[847,814,1173,1283]	1	hSpCas9	negative selection	9509363
55742902	55742925	15	-	27260156	TC32	viability	CTCCTCTGCGACCCCTCGCCCGG	PRTG	ENSG00000166450	0.0935105252974955	[493]	[430,406,474,686]	1	hSpCas9	negative selection	9509364
55742900	55742923	15	+	27260156	TC32	viability	AGCCGGGCGAGGGGTCGCAGAGG	PRTG	ENSG00000166450	-0.5967641901525669	[41]	[24,0,65,27]	-8	hSpCas9	negative selection	9509365
55673594	55673617	15	+	27869803	HPAFII	viability after 27 days	TTTGGCTGGGATTGGCAGCCAGG	PRTG	ENSG00000166450	1.0465266831262685	[182]	[213,185,NaN]	8	hSpCas9	negative selection	9554076
55677870	55677893	15	+	27869803	HPAFII	viability after 27 days	AAGAATGGCTGAGCTTGACATGG	PRTG	ENSG00000166450	0.6879787430070324	[160]	[233,54,NaN]	5	hSpCas9	negative selection	9554077
55680082	55680105	15	+	27869803	HPAFII	viability after 27 days	TGTAAAGTTGCGTGTGCCAGGGG	PRTG	ENSG00000166450	0.994778026143235	[285]	[393,220,NaN]	7	hSpCas9	negative selection	9554078
55682395	55682418	15	+	27869803	HPAFII	viability after 27 days	TTTACGTCGGTGGGCTACAGTGG	PRTG	ENSG00000166450	0.3402988805930779	[282]	[237,146,NaN]	2	hSpCas9	negative selection	9554079
55683786	55683809	15	-	27869803	HPAFII	viability after 27 days	CTCTACCTATGACTATGGACAGG	PRTG	ENSG00000166450	-0.36240474800890443	[334]	[142,131,NaN]	-3	hSpCas9	negative selection	9554080
55742819	55742842	15	+	27869803	HPAFII	viability after 27 days	CAGAAGAAAGCGCGCCCACCTGG	PRTG	ENSG00000166450	1.4532685861953984	[200]	[446,157,NaN]	9	hSpCas9	negative selection	9554081
55673594	55673617	15	+	27869803	HPAFII	viability after 15 days	TTTGGCTGGGATTGGCAGCCAGG	PRTG	ENSG00000166450	0.14168915853851027	[182]	[269,183,NaN]	1	hSpCas9	negative selection	9636525
55677870	55677893	15	+	27869803	HPAFII	viability after 15 days	AAGAATGGCTGAGCTTGACATGG	PRTG	ENSG00000166450	1.2727850272857624	[160]	[681,253,NaN]	9	hSpCas9	negative selection	9636526
55680082	55680105	15	+	27869803	HPAFII	viability after 15 days	TGTAAAGTTGCGTGTGCCAGGGG	PRTG	ENSG00000166450	1.0646072988196558	[285]	[1002,418,NaN]	9	hSpCas9	negative selection	9636527
55682395	55682418	15	+	27869803	HPAFII	viability after 15 days	TTTACGTCGGTGGGCTACAGTGG	PRTG	ENSG00000166450	0.6859856619337735	[282]	[640,394,NaN]	7	hSpCas9	negative selection	9636528
55683786	55683809	15	-	27869803	HPAFII	viability after 15 days	CTCTACCTATGACTATGGACAGG	PRTG	ENSG00000166450	-0.5750571181149926	[334]	[171,284,NaN]	-6	hSpCas9	negative selection	9636529
55742819	55742842	15	+	27869803	HPAFII	viability after 15 days	CAGAAGAAAGCGCGCCCACCTGG	PRTG	ENSG00000166450	0.8112836062625975	[200]	[732,158,NaN]	8	hSpCas9	negative selection	9636530
55673594	55673617	15	+	27869803	ASPC1	viability after 36 days	TTTGGCTGGGATTGGCAGCCAGG	PRTG	ENSG00000166450	-0.9698410003216267	[448]	[79,44,106]	-7	hSpCas9	negative selection	9718974
55677870	55677893	15	+	27869803	ASPC1	viability after 36 days	AAGAATGGCTGAGCTTGACATGG	PRTG	ENSG00000166450	-0.7875946504355333	[694]	[190,90,142]	-6	hSpCas9	negative selection	9718975
55680082	55680105	15	+	27869803	ASPC1	viability after 36 days	TGTAAAGTTGCGTGTGCCAGGGG	PRTG	ENSG00000166450	0.058973325576474056	[929]	[467,353,230]	0	hSpCas9	negative selection	9718976
55682395	55682418	15	+	27869803	ASPC1	viability after 36 days	TTTACGTCGGTGGGCTACAGTGG	PRTG	ENSG00000166450	-0.06783460919750228	[960]	[334,410,233]	0	hSpCas9	negative selection	9718977
55683786	55683809	15	-	27869803	ASPC1	viability after 36 days	CTCTACCTATGACTATGGACAGG	PRTG	ENSG00000166450	-0.29035378616456226	[506]	[119,191,122]	-3	hSpCas9	negative selection	9718978
55742819	55742842	15	+	27869803	ASPC1	viability after 36 days	CAGAAGAAAGCGCGCCCACCTGG	PRTG	ENSG00000166450	0.6162721332114046	[630]	[298,609,144]	6	hSpCas9	negative selection	9718979
55673594	55673617	15	+	27869803	PATU8988S	viability after 35 days	TTTGGCTGGGATTGGCAGCCAGG	PRTG	ENSG00000166450	0.17646580101508413	[313]	[106,178,NaN]	2	hSpCas9	negative selection	9801423
55677870	55677893	15	+	27869803	PATU8988S	viability after 35 days	AAGAATGGCTGAGCTTGACATGG	PRTG	ENSG00000166450	-0.13909933749885683	[479]	[197,152,NaN]	-1	hSpCas9	negative selection	9801424
55680082	55680105	15	+	27869803	PATU8988S	viability after 35 days	TGTAAAGTTGCGTGTGCCAGGGG	PRTG	ENSG00000166450	0.07407493205722082	[774]	[361,294,NaN]	0	hSpCas9	negative selection	9801425
55682395	55682418	15	+	27869803	PATU8988S	viability after 35 days	TTTACGTCGGTGGGCTACAGTGG	PRTG	ENSG00000166450	-0.4327859578679881	[819]	[315,172,NaN]	-4	hSpCas9	negative selection	9801426
55683786	55683809	15	-	27869803	PATU8988S	viability after 35 days	CTCTACCTATGACTATGGACAGG	PRTG	ENSG00000166450	0.4029482061505256	[539]	[313,260,NaN]	4	hSpCas9	negative selection	9801427
55742819	55742842	15	+	27869803	PATU8988S	viability after 35 days	CAGAAGAAAGCGCGCCCACCTGG	PRTG	ENSG00000166450	0.4461299475536813	[478]	[186,338,NaN]	5	hSpCas9	negative selection	9801428
55673594	55673617	15	+	27869803	PATU8988S	viability after 31 days	TTTGGCTGGGATTGGCAGCCAGG	PRTG	ENSG00000166450	0.459327955576984	[313]	[99,263,NaN]	5	hSpCas9	negative selection	9883872
55677870	55677893	15	+	27869803	PATU8988S	viability after 31 days	AAGAATGGCTGAGCTTGACATGG	PRTG	ENSG00000166450	-0.5505508844096785	[479]	[120,142,NaN]	-6	hSpCas9	negative selection	9883873
55680082	55680105	15	+	27869803	PATU8988S	viability after 31 days	TGTAAAGTTGCGTGTGCCAGGGG	PRTG	ENSG00000166450	0.42018590054616245	[774]	[354,487,NaN]	5	hSpCas9	negative selection	9883874
55682395	55682418	15	+	27869803	PATU8988S	viability after 31 days	TTTACGTCGGTGGGCTACAGTGG	PRTG	ENSG00000166450	-0.18547528932057733	[819]	[305,263,NaN]	-2	hSpCas9	negative selection	9883875
55683786	55683809	15	-	27869803	PATU8988S	viability after 31 days	CTCTACCTATGACTATGGACAGG	PRTG	ENSG00000166450	0.13318153511926442	[539]	[163,327,NaN]	1	hSpCas9	negative selection	9883876
55742819	55742842	15	+	27869803	PATU8988S	viability after 31 days	CAGAAGAAAGCGCGCCCACCTGG	PRTG	ENSG00000166450	0.5088449583903989	[478]	[141,436,NaN]	6	hSpCas9	negative selection	9883877
55673594	55673617	15	+	27869803	HPAFII	viability after 35 days	TTTGGCTGGGATTGGCAGCCAGG	PRTG	ENSG00000166450	1.7506939104508574	[182]	[188,449,NaN]	9	hSpCas9	negative selection	9966321
55677870	55677893	15	+	27869803	HPAFII	viability after 35 days	AAGAATGGCTGAGCTTGACATGG	PRTG	ENSG00000166450	0.6680019792034739	[160]	[192,57,NaN]	4	hSpCas9	negative selection	9966322
55680082	55680105	15	+	27869803	HPAFII	viability after 35 days	TGTAAAGTTGCGTGTGCCAGGGG	PRTG	ENSG00000166450	0.9768952607045464	[285]	[347,213,NaN]	6	hSpCas9	negative selection	9966323
55682395	55682418	15	+	27869803	HPAFII	viability after 35 days	TTTACGTCGGTGGGCTACAGTGG	PRTG	ENSG00000166450	0.5419764516201339	[282]	[217,197,NaN]	3	hSpCas9	negative selection	9966324
55683786	55683809	15	-	27869803	HPAFII	viability after 35 days	CTCTACCTATGACTATGGACAGG	PRTG	ENSG00000166450	0.09325540414467598	[334]	[131,235,NaN]	0	hSpCas9	negative selection	9966325
55742819	55742842	15	+	27869803	HPAFII	viability after 35 days	CAGAAGAAAGCGCGCCCACCTGG	PRTG	ENSG00000166450	1.565130078124173	[200]	[381,209,NaN]	9	hSpCas9	negative selection	9966326
55673594	55673617	15	+	27869803	HPAFII	viability after 31 days	TTTGGCTGGGATTGGCAGCCAGG	PRTG	ENSG00000166450	1.5714175655304676	[182]	[220,396,NaN]	9	hSpCas9	negative selection	10048770
55677870	55677893	15	+	27869803	HPAFII	viability after 31 days	AAGAATGGCTGAGCTTGACATGG	PRTG	ENSG00000166450	0.7228672002740806	[160]	[218,72,NaN]	5	hSpCas9	negative selection	10048771
55680082	55680105	15	+	27869803	HPAFII	viability after 31 days	TGTAAAGTTGCGTGTGCCAGGGG	PRTG	ENSG00000166450	0.9110854321189946	[285]	[297,305,NaN]	6	hSpCas9	negative selection	10048772
55682395	55682418	15	+	27869803	HPAFII	viability after 31 days	TTTACGTCGGTGGGCTACAGTGG	PRTG	ENSG00000166450	0.8613904776272341	[282]	[311,262,NaN]	6	hSpCas9	negative selection	10048773
55683786	55683809	15	-	27869803	HPAFII	viability after 31 days	CTCTACCTATGACTATGGACAGG	PRTG	ENSG00000166450	0.2419961623580122	[334]	[229,213,NaN]	1	hSpCas9	negative selection	10048774
55742819	55742842	15	+	27869803	HPAFII	viability after 31 days	CAGAAGAAAGCGCGCCCACCTGG	PRTG	ENSG00000166450	1.3125223182941848	[200]	[339,214,NaN]	8	hSpCas9	negative selection	10048775
55641154	55641177	15	-	28162770	P31FUJ	viability	GCTTACAACAACATAGACGATGG	PRTG	ENSG00000166450	1.0123102934221528	[80]	[191]	9	hSpCas9	negative selection	10218392
55672582	55672605	15	+	28162770	P31FUJ	viability	GAAATGGTGGTACAGTTCAGAGG	PRTG	ENSG00000166450	0.5376557204758123	[825]	[1408]	6	hSpCas9	negative selection	10218393
55639655	55639678	15	+	28162770	P31FUJ	viability	GAACCAAAGAAGCATTCTGCAGG	PRTG	ENSG00000166450	0.16629375099544358	[181]	[239]	1	hSpCas9	negative selection	10218394
55628973	55628996	15	+	28162770	P31FUJ	viability	CAAGTTTTCTAGCAAAGCCATGG	PRTG	ENSG00000166450	-0.8177647051355348	[32]	[21]	-6	hSpCas9	negative selection	10218395
55628876	55628899	15	-	28162770	P31FUJ	viability	GGAGCTGGCAGTACTTCCAAAGG	PRTG	ENSG00000166450	-1.2583372965215163	[113]	[55]	-7	hSpCas9	negative selection	10218396
55742856	55742879	15	+	28162770	P31FUJ	viability	GCAGCAGGAGCAGGAGCGCGCGG	PRTG	ENSG00000166450	-1.265592139532048	[177]	[86]	-7	hSpCas9	negative selection	10218397
55742825	55742848	15	+	28162770	P31FUJ	viability	AAAGCGCGCCCACCTGGCAAAGG	PRTG	ENSG00000166450	0.5412765627689268	[306]	[524]	6	hSpCas9	negative selection	10218398
55679307	55679330	15	-	28162770	P31FUJ	viability	GGAAGGAAGATACATTCGAATGG	PRTG	ENSG00000166450	0.7019063353339022	[225]	[431]	7	hSpCas9	negative selection	10218399
55677973	55677996	15	-	28162770	P31FUJ	viability	TGCATGGCTGAGAATAGCCAAGG	PRTG	ENSG00000166450	0.49684004894596856	[315]	[523]	5	hSpCas9	negative selection	10218400
55641154	55641177	15	-	28162770	TF1	viability	GCTTACAACAACATAGACGATGG	PRTG	ENSG00000166450	NaN	[NaN]	[39]	1	hSpCas9	negative selection	10387758
55672582	55672605	15	+	28162770	TF1	viability	GAAATGGTGGTACAGTTCAGAGG	PRTG	ENSG00000166450	NaN	[NaN]	[777]	1	hSpCas9	negative selection	10387759
55639655	55639678	15	+	28162770	TF1	viability	GAACCAAAGAAGCATTCTGCAGG	PRTG	ENSG00000166450	NaN	[NaN]	[148]	1	hSpCas9	negative selection	10387760
55628973	55628996	15	+	28162770	TF1	viability	CAAGTTTTCTAGCAAAGCCATGG	PRTG	ENSG00000166450	NaN	[NaN]	[36]	1	hSpCas9	negative selection	10387761
55628876	55628899	15	-	28162770	TF1	viability	GGAGCTGGCAGTACTTCCAAAGG	PRTG	ENSG00000166450	NaN	[NaN]	[128]	1	hSpCas9	negative selection	10387762
55742856	55742879	15	+	28162770	TF1	viability	GCAGCAGGAGCAGGAGCGCGCGG	PRTG	ENSG00000166450	NaN	[NaN]	[21]	1	hSpCas9	negative selection	10387763
55742825	55742848	15	+	28162770	TF1	viability	AAAGCGCGCCCACCTGGCAAAGG	PRTG	ENSG00000166450	NaN	[NaN]	[456]	1	hSpCas9	negative selection	10387764
55679307	55679330	15	-	28162770	TF1	viability	GGAAGGAAGATACATTCGAATGG	PRTG	ENSG00000166450	NaN	[NaN]	[232]	1	hSpCas9	negative selection	10387765
55677973	55677996	15	-	28162770	TF1	viability	TGCATGGCTGAGAATAGCCAAGG	PRTG	ENSG00000166450	NaN	[NaN]	[313]	1	hSpCas9	negative selection	10387766
55641154	55641177	15	-	28162770	SKM1	viability	GCTTACAACAACATAGACGATGG	PRTG	ENSG00000166450	0.7629608026991506	[28]	[86]	7	hSpCas9	negative selection	10557124
55672582	55672605	15	+	28162770	SKM1	viability	GAAATGGTGGTACAGTTCAGAGG	PRTG	ENSG00000166450	0.0026800417654635478	[200]	[355]	0	hSpCas9	negative selection	10557125
55639655	55639678	15	+	28162770	SKM1	viability	GAACCAAAGAAGCATTCTGCAGG	PRTG	ENSG00000166450	0.6436618743268063	[41]	[115]	6	hSpCas9	negative selection	10557126
55628973	55628996	15	+	28162770	SKM1	viability	CAAGTTTTCTAGCAAAGCCATGG	PRTG	ENSG00000166450	1.307281318922961	[7]	[34]	9	hSpCas9	negative selection	10557127
55628876	55628899	15	-	28162770	SKM1	viability	GGAGCTGGCAGTACTTCCAAAGG	PRTG	ENSG00000166450	-0.7776075786635521	[31]	[32]	-5	hSpCas9	negative selection	10557128
55742856	55742879	15	+	28162770	SKM1	viability	GCAGCAGGAGCAGGAGCGCGCGG	PRTG	ENSG00000166450	-1.3321964303411895	[46]	[32]	-7	hSpCas9	negative selection	10557129
55742825	55742848	15	+	28162770	SKM1	viability	AAAGCGCGCCCACCTGGCAAAGG	PRTG	ENSG00000166450	-0.017397386980435914	[74]	[130]	0	hSpCas9	negative selection	10557130
55679307	55679330	15	-	28162770	SKM1	viability	GGAAGGAAGATACATTCGAATGG	PRTG	ENSG00000166450	0.3585705476198154	[59]	[135]	3	hSpCas9	negative selection	10557131
55677973	55677996	15	-	28162770	SKM1	viability	TGCATGGCTGAGAATAGCCAAGG	PRTG	ENSG00000166450	0.23313985617045546	[76]	[159]	2	hSpCas9	negative selection	10557132
55641154	55641177	15	-	28162770	SKM1	viability	GCTTACAACAACATAGACGATGG	PRTG	ENSG00000166450	0.7629608026991506	[28]	[86]	7	hSpCas9	negative selection	10726490
55672582	55672605	15	+	28162770	SKM1	viability	GAAATGGTGGTACAGTTCAGAGG	PRTG	ENSG00000166450	0.0026800417654635478	[200]	[355]	0	hSpCas9	negative selection	10726491
55639655	55639678	15	+	28162770	SKM1	viability	GAACCAAAGAAGCATTCTGCAGG	PRTG	ENSG00000166450	0.6436618743268063	[41]	[115]	6	hSpCas9	negative selection	10726492
55628973	55628996	15	+	28162770	SKM1	viability	CAAGTTTTCTAGCAAAGCCATGG	PRTG	ENSG00000166450	1.307281318922961	[7]	[34]	9	hSpCas9	negative selection	10726493
55628876	55628899	15	-	28162770	SKM1	viability	GGAGCTGGCAGTACTTCCAAAGG	PRTG	ENSG00000166450	-0.7776075786635521	[31]	[32]	-5	hSpCas9	negative selection	10726494
55742856	55742879	15	+	28162770	SKM1	viability	GCAGCAGGAGCAGGAGCGCGCGG	PRTG	ENSG00000166450	-1.3321964303411895	[46]	[32]	-7	hSpCas9	negative selection	10726495
55742825	55742848	15	+	28162770	SKM1	viability	AAAGCGCGCCCACCTGGCAAAGG	PRTG	ENSG00000166450	-0.017397386980435914	[74]	[130]	0	hSpCas9	negative selection	10726496
55679307	55679330	15	-	28162770	SKM1	viability	GGAAGGAAGATACATTCGAATGG	PRTG	ENSG00000166450	0.3585705476198154	[59]	[135]	3	hSpCas9	negative selection	10726497
55677973	55677996	15	-	28162770	SKM1	viability	TGCATGGCTGAGAATAGCCAAGG	PRTG	ENSG00000166450	0.23313985617045546	[76]	[159]	2	hSpCas9	negative selection	10726498
55641154	55641177	15	-	28162770	PL21	viability	GCTTACAACAACATAGACGATGG	PRTG	ENSG00000166450	1.3894099656510597	[106]	[121]	9	hSpCas9	negative selection	10895856
55672582	55672605	15	+	28162770	PL21	viability	GAAATGGTGGTACAGTTCAGAGG	PRTG	ENSG00000166450	0.6532882555066353	[522]	[357]	5	hSpCas9	negative selection	10895857
55639655	55639678	15	+	28162770	PL21	viability	GAACCAAAGAAGCATTCTGCAGG	PRTG	ENSG00000166450	1.8799613015519174	[205]	[329]	9	hSpCas9	negative selection	10895858
55628973	55628996	15	+	28162770	PL21	viability	CAAGTTTTCTAGCAAAGCCATGG	PRTG	ENSG00000166450	1.5220677093766828	[27]	[34]	9	hSpCas9	negative selection	10895859
55628876	55628899	15	-	28162770	PL21	viability	GGAGCTGGCAGTACTTCCAAAGG	PRTG	ENSG00000166450	-0.04629828081377896	[120]	[50]	0	hSpCas9	negative selection	10895860
55742856	55742879	15	+	28162770	PL21	viability	GCAGCAGGAGCAGGAGCGCGCGG	PRTG	ENSG00000166450	-1.0968421232678112	[171]	[34]	-6	hSpCas9	negative selection	10895861
55742825	55742848	15	+	28162770	PL21	viability	AAAGCGCGCCCACCTGGCAAAGG	PRTG	ENSG00000166450	0.798451668869496	[250]	[189]	6	hSpCas9	negative selection	10895862
55679307	55679330	15	-	28162770	PL21	viability	GGAAGGAAGATACATTCGAATGG	PRTG	ENSG00000166450	0.4079444996027218	[212]	[122]	3	hSpCas9	negative selection	10895863
55677973	55677996	15	-	28162770	PL21	viability	TGCATGGCTGAGAATAGCCAAGG	PRTG	ENSG00000166450	0.8717564974646584	[279]	[222]	7	hSpCas9	negative selection	10895864
55641154	55641177	15	-	28162770	P31FUJ	viability	GCTTACAACAACATAGACGATGG	PRTG	ENSG00000166450	1.0123102934221528	[80]	[191]	9	hSpCas9	negative selection	11065222
55672582	55672605	15	+	28162770	P31FUJ	viability	GAAATGGTGGTACAGTTCAGAGG	PRTG	ENSG00000166450	0.5376557204758123	[825]	[1408]	6	hSpCas9	negative selection	11065223
55639655	55639678	15	+	28162770	P31FUJ	viability	GAACCAAAGAAGCATTCTGCAGG	PRTG	ENSG00000166450	0.16629375099544358	[181]	[239]	1	hSpCas9	negative selection	11065224
55628973	55628996	15	+	28162770	P31FUJ	viability	CAAGTTTTCTAGCAAAGCCATGG	PRTG	ENSG00000166450	-0.8177647051355348	[32]	[21]	-6	hSpCas9	negative selection	11065225
55628876	55628899	15	-	28162770	P31FUJ	viability	GGAGCTGGCAGTACTTCCAAAGG	PRTG	ENSG00000166450	-1.2583372965215163	[113]	[55]	-7	hSpCas9	negative selection	11065226
55742856	55742879	15	+	28162770	P31FUJ	viability	GCAGCAGGAGCAGGAGCGCGCGG	PRTG	ENSG00000166450	-1.265592139532048	[177]	[86]	-7	hSpCas9	negative selection	11065227
55742825	55742848	15	+	28162770	P31FUJ	viability	AAAGCGCGCCCACCTGGCAAAGG	PRTG	ENSG00000166450	0.5412765627689268	[306]	[524]	6	hSpCas9	negative selection	11065228
55679307	55679330	15	-	28162770	P31FUJ	viability	GGAAGGAAGATACATTCGAATGG	PRTG	ENSG00000166450	0.7019063353339022	[225]	[431]	7	hSpCas9	negative selection	11065229
55677973	55677996	15	-	28162770	P31FUJ	viability	TGCATGGCTGAGAATAGCCAAGG	PRTG	ENSG00000166450	0.49684004894596856	[315]	[523]	5	hSpCas9	negative selection	11065230
55641154	55641177	15	-	28162770	OCIAML5	viability	GCTTACAACAACATAGACGATGG	PRTG	ENSG00000166450	-0.6980329421915759	[70]	[78]	-4	hSpCas9	negative selection	11234588
55672582	55672605	15	+	28162770	OCIAML5	viability	GAAATGGTGGTACAGTTCAGAGG	PRTG	ENSG00000166450	0.6740022408035904	[424]	[1223]	6	hSpCas9	negative selection	11234589
55639655	55639678	15	+	28162770	OCIAML5	viability	GAACCAAAGAAGCATTCTGCAGG	PRTG	ENSG00000166450	0.7296207978242983	[146]	[439]	6	hSpCas9	negative selection	11234590
55628973	55628996	15	+	28162770	OCIAML5	viability	CAAGTTTTCTAGCAAAGCCATGG	PRTG	ENSG00000166450	0.06220355511011899	[25]	[48]	0	hSpCas9	negative selection	11234591
55628876	55628899	15	-	28162770	OCIAML5	viability	GGAGCTGGCAGTACTTCCAAAGG	PRTG	ENSG00000166450	-0.60764784319755	[64]	[76]	-4	hSpCas9	negative selection	11234592
55742856	55742879	15	+	28162770	OCIAML5	viability	GCAGCAGGAGCAGGAGCGCGCGG	PRTG	ENSG00000166450	-0.7126635141985806	[68]	[75]	-5	hSpCas9	negative selection	11234593
55742825	55742848	15	+	28162770	OCIAML5	viability	AAAGCGCGCCCACCTGGCAAAGG	PRTG	ENSG00000166450	0.25074423471977847	[175]	[377]	2	hSpCas9	negative selection	11234594
55679307	55679330	15	-	28162770	OCIAML5	viability	GGAAGGAAGATACATTCGAATGG	PRTG	ENSG00000166450	0.8393021568620982	[134]	[435]	7	hSpCas9	negative selection	11234595
55677973	55677996	15	-	28162770	OCIAML5	viability	TGCATGGCTGAGAATAGCCAAGG	PRTG	ENSG00000166450	0.5231773385558217	[169]	[440]	4	hSpCas9	negative selection	11234596
55641154	55641177	15	-	28162770	EOL1	viability	GCTTACAACAACATAGACGATGG	PRTG	ENSG00000166450	-0.7205357215881925	[146]	[46]	-5	hSpCas9	negative selection	11403954
55672582	55672605	15	+	28162770	EOL1	viability	GAAATGGTGGTACAGTTCAGAGG	PRTG	ENSG00000166450	0.40468029907126346	[779]	[543]	3	hSpCas9	negative selection	11403955
55639655	55639678	15	+	28162770	EOL1	viability	GAACCAAAGAAGCATTCTGCAGG	PRTG	ENSG00000166450	-0.04118232634471941	[415]	[212]	0	hSpCas9	negative selection	11403956
55628973	55628996	15	+	28162770	EOL1	viability	CAAGTTTTCTAGCAAAGCCATGG	PRTG	ENSG00000166450	0.013084446172191733	[78]	[41]	0	hSpCas9	negative selection	11403957
55628876	55628899	15	-	28162770	EOL1	viability	GGAGCTGGCAGTACTTCCAAAGG	PRTG	ENSG00000166450	-0.6135481241126473	[211]	[72]	-4	hSpCas9	negative selection	11403958
55742856	55742879	15	+	28162770	EOL1	viability	GCAGCAGGAGCAGGAGCGCGCGG	PRTG	ENSG00000166450	-1.280023372678669	[294]	[63]	-7	hSpCas9	negative selection	11403959
55742825	55742848	15	+	28162770	EOL1	viability	AAAGCGCGCCCACCTGGCAAAGG	PRTG	ENSG00000166450	0.9161599860778158	[344]	[342]	7	hSpCas9	negative selection	11403960
55679307	55679330	15	-	28162770	EOL1	viability	GGAAGGAAGATACATTCGAATGG	PRTG	ENSG00000166450	0.7211656430206278	[288]	[250]	6	hSpCas9	negative selection	11403961
55677973	55677996	15	-	28162770	EOL1	viability	TGCATGGCTGAGAATAGCCAAGG	PRTG	ENSG00000166450	0.3758693881741548	[372]	[254]	3	hSpCas9	negative selection	11403962
55641154	55641177	15	-	28162770	MOLM13	viability	GCTTACAACAACATAGACGATGG	PRTG	ENSG00000166450	0.4007751856860418	[153]	[146]	3	hSpCas9	negative selection	11573320
55672582	55672605	15	+	28162770	MOLM13	viability	GAAATGGTGGTACAGTTCAGAGG	PRTG	ENSG00000166450	0.650419500832615	[822]	[933]	5	hSpCas9	negative selection	11573321
55639655	55639678	15	+	28162770	MOLM13	viability	GAACCAAAGAAGCATTCTGCAGG	PRTG	ENSG00000166450	1.2784610162857257	[255]	[448]	8	hSpCas9	negative selection	11573322
55628973	55628996	15	+	28162770	MOLM13	viability	CAAGTTTTCTAGCAAAGCCATGG	PRTG	ENSG00000166450	1.3056179526457017	[46]	[83]	8	hSpCas9	negative selection	11573323
55628876	55628899	15	-	28162770	MOLM13	viability	GGAGCTGGCAGTACTTCCAAAGG	PRTG	ENSG00000166450	0.5632372581320599	[160]	[171]	4	hSpCas9	negative selection	11573324
55742856	55742879	15	+	28162770	MOLM13	viability	GCAGCAGGAGCAGGAGCGCGCGG	PRTG	ENSG00000166450	-2.619573459705761	[152]	[17]	-8	hSpCas9	negative selection	11573325
55742825	55742848	15	+	28162770	MOLM13	viability	AAAGCGCGCCCACCTGGCAAAGG	PRTG	ENSG00000166450	0.3823379374293656	[329]	[310]	3	hSpCas9	negative selection	11573326
55679307	55679330	15	-	28162770	MOLM13	viability	GGAAGGAAGATACATTCGAATGG	PRTG	ENSG00000166450	0.40254862787726114	[270]	[258]	3	hSpCas9	negative selection	11573327
55677973	55677996	15	-	28162770	MOLM13	viability	TGCATGGCTGAGAATAGCCAAGG	PRTG	ENSG00000166450	0.11550749011550254	[382]	[299]	0	hSpCas9	negative selection	11573328
55641154	55641177	15	-	28162770	HEL	viability	GCTTACAACAACATAGACGATGG	PRTG	ENSG00000166450	0.758216049420293	[155]	[168]	6	hSpCas9	negative selection	11742686
55672582	55672605	15	+	28162770	HEL	viability	GAAATGGTGGTACAGTTCAGAGG	PRTG	ENSG00000166450	0.6065898285273916	[686]	[669]	5	hSpCas9	negative selection	11742687
55639655	55639678	15	+	28162770	HEL	viability	GAACCAAAGAAGCATTCTGCAGG	PRTG	ENSG00000166450	0.9149917678635295	[259]	[313]	7	hSpCas9	negative selection	11742688
55628973	55628996	15	+	28162770	HEL	viability	CAAGTTTTCTAGCAAAGCCATGG	PRTG	ENSG00000166450	-0.33029412039937345	[52]	[26]	-2	hSpCas9	negative selection	11742689
55628876	55628899	15	-	28162770	HEL	viability	GGAGCTGGCAGTACTTCCAAAGG	PRTG	ENSG00000166450	-0.8238289679185689	[151]	[54]	-5	hSpCas9	negative selection	11742690
55742856	55742879	15	+	28162770	HEL	viability	GCAGCAGGAGCAGGAGCGCGCGG	PRTG	ENSG00000166450	0.8088960197552674	[212]	[238]	7	hSpCas9	negative selection	11742691
55742825	55742848	15	+	28162770	HEL	viability	AAAGCGCGCCCACCTGGCAAAGG	PRTG	ENSG00000166450	0.03105899290342129	[326]	[213]	0	hSpCas9	negative selection	11742692
55679307	55679330	15	-	28162770	HEL	viability	GGAAGGAAGATACATTCGAATGG	PRTG	ENSG00000166450	1.064470983853209	[214]	[287]	8	hSpCas9	negative selection	11742693
55677973	55677996	15	-	28162770	HEL	viability	TGCATGGCTGAGAATAGCCAAGG	PRTG	ENSG00000166450	0.5324154170943585	[325]	[301]	4	hSpCas9	negative selection	11742694
55641154	55641177	15	-	28162770	MV411	viability	GCTTACAACAACATAGACGATGG	PRTG	ENSG00000166450	-0.5826374477749121	[63]	[35]	-4	hSpCas9	negative selection	11912052
55672582	55672605	15	+	28162770	MV411	viability	GAAATGGTGGTACAGTTCAGAGG	PRTG	ENSG00000166450	0.32989971097474835	[594]	[629]	3	hSpCas9	negative selection	11912053
55639655	55639678	15	+	28162770	MV411	viability	GAACCAAAGAAGCATTCTGCAGG	PRTG	ENSG00000166450	0.726442876071319	[192]	[268]	6	hSpCas9	negative selection	11912054
55628973	55628996	15	+	28162770	MV411	viability	CAAGTTTTCTAGCAAAGCCATGG	PRTG	ENSG00000166450	0.6280415529977452	[52]	[68]	5	hSpCas9	negative selection	11912055
55628876	55628899	15	-	28162770	MV411	viability	GGAGCTGGCAGTACTTCCAAAGG	PRTG	ENSG00000166450	0.40999056356873537	[108]	[121]	3	hSpCas9	negative selection	11912056
55742856	55742879	15	+	28162770	MV411	viability	GCAGCAGGAGCAGGAGCGCGCGG	PRTG	ENSG00000166450	-1.5877515794715544	[156]	[43]	-7	hSpCas9	negative selection	11912057
55742825	55742848	15	+	28162770	MV411	viability	AAAGCGCGCCCACCTGGCAAAGG	PRTG	ENSG00000166450	0.5346494402140379	[285]	[348]	5	hSpCas9	negative selection	11912058
55679307	55679330	15	-	28162770	MV411	viability	GGAAGGAAGATACATTCGAATGG	PRTG	ENSG00000166450	0.6893262697110505	[172]	[234]	6	hSpCas9	negative selection	11912059
55677973	55677996	15	-	28162770	MV411	viability	TGCATGGCTGAGAATAGCCAAGG	PRTG	ENSG00000166450	0.4583343332813936	[215]	[249]	4	hSpCas9	negative selection	11912060
55641154	55641177	15	-	28162770	MONOMAC1	viability	GCTTACAACAACATAGACGATGG	PRTG	ENSG00000166450	1.6635600962750297	[56]	[206]	9	hSpCas9	negative selection	12081418
55672582	55672605	15	+	28162770	MONOMAC1	viability	GAAATGGTGGTACAGTTCAGAGG	PRTG	ENSG00000166450	0.31117616099076395	[340]	[484]	3	hSpCas9	negative selection	12081419
55639655	55639678	15	+	28162770	MONOMAC1	viability	GAACCAAAGAAGCATTCTGCAGG	PRTG	ENSG00000166450	-0.4557711154597219	[133]	[111]	-4	hSpCas9	negative selection	12081420
55628973	55628996	15	+	28162770	MONOMAC1	viability	CAAGTTTTCTAGCAAAGCCATGG	PRTG	ENSG00000166450	-1.78199934778071	[23]	[7]	-8	hSpCas9	negative selection	12081421
55628876	55628899	15	-	28162770	MONOMAC1	viability	GGAGCTGGCAGTACTTCCAAAGG	PRTG	ENSG00000166450	-0.0975011735086393	[83]	[89]	-1	hSpCas9	negative selection	12081422
55742856	55742879	15	+	28162770	MONOMAC1	viability	GCAGCAGGAGCAGGAGCGCGCGG	PRTG	ENSG00000166450	1.1792310820547147	[98]	[256]	8	hSpCas9	negative selection	12081423
55742825	55742848	15	+	28162770	MONOMAC1	viability	AAAGCGCGCCCACCTGGCAAAGG	PRTG	ENSG00000166450	-0.17699909382300857	[142]	[144]	-1	hSpCas9	negative selection	12081424
55679307	55679330	15	-	28162770	MONOMAC1	viability	GGAAGGAAGATACATTCGAATGG	PRTG	ENSG00000166450	-0.2391623227322302	[138]	[134]	-2	hSpCas9	negative selection	12081425
55677973	55677996	15	-	28162770	MONOMAC1	viability	TGCATGGCTGAGAATAGCCAAGG	PRTG	ENSG00000166450	0.023229273168506537	[193]	[225]	0	hSpCas9	negative selection	12081426
55641154	55641177	15	-	28162770	OCIAML2	viability	GCTTACAACAACATAGACGATGG	PRTG	ENSG00000166450	0.21866933529373056	[19]	[128]	2	hSpCas9	negative selection	12250784
55672582	55672605	15	+	28162770	OCIAML2	viability	GAAATGGTGGTACAGTTCAGAGG	PRTG	ENSG00000166450	0.2599379977258942	[112]	[749]	2	hSpCas9	negative selection	12250785
55639655	55639678	15	+	28162770	OCIAML2	viability	GAACCAAAGAAGCATTCTGCAGG	PRTG	ENSG00000166450	0.27561358251205575	[30]	[207]	2	hSpCas9	negative selection	12250786
55628973	55628996	15	+	28162770	OCIAML2	viability	CAAGTTTTCTAGCAAAGCCATGG	PRTG	ENSG00000166450	-1.318626731797111	[8]	[19]	-7	hSpCas9	negative selection	12250787
55628876	55628899	15	-	28162770	OCIAML2	viability	GGAGCTGGCAGTACTTCCAAAGG	PRTG	ENSG00000166450	-0.2182426636078758	[16]	[80]	-2	hSpCas9	negative selection	12250788
55742856	55742879	15	+	28162770	OCIAML2	viability	GCAGCAGGAGCAGGAGCGCGCGG	PRTG	ENSG00000166450	-1.8367577240400588	[28]	[44]	-8	hSpCas9	negative selection	12250789
55742825	55742848	15	+	28162770	OCIAML2	viability	AAAGCGCGCCCACCTGGCAAAGG	PRTG	ENSG00000166450	-0.2466281510440561	[63]	[298]	-2	hSpCas9	negative selection	12250790
55679307	55679330	15	-	28162770	OCIAML2	viability	GGAAGGAAGATACATTCGAATGG	PRTG	ENSG00000166450	-0.08671484345909794	[40]	[213]	0	hSpCas9	negative selection	12250791
55677973	55677996	15	-	28162770	OCIAML2	viability	TGCATGGCTGAGAATAGCCAAGG	PRTG	ENSG00000166450	0.3521003227023587	[39]	[282]	3	hSpCas9	negative selection	12250792
55641154	55641177	15	-	28162770	OCIAML3	viability	GCTTACAACAACATAGACGATGG	PRTG	ENSG00000166450	1.0562463206487123	[35]	[225]	8	hSpCas9	negative selection	12420150
55672582	55672605	15	+	28162770	OCIAML3	viability	GAAATGGTGGTACAGTTCAGAGG	PRTG	ENSG00000166450	0.18883100212640946	[194]	[670]	1	hSpCas9	negative selection	12420151
55639655	55639678	15	+	28162770	OCIAML3	viability	GAACCAAAGAAGCATTCTGCAGG	PRTG	ENSG00000166450	0.33347985989146883	[50]	[193]	3	hSpCas9	negative selection	12420152
55628973	55628996	15	+	28162770	OCIAML3	viability	CAAGTTTTCTAGCAAAGCCATGG	PRTG	ENSG00000166450	-1.594007640324163	[21]	[21]	-8	hSpCas9	negative selection	12420153
55628876	55628899	15	-	28162770	OCIAML3	viability	GGAGCTGGCAGTACTTCCAAAGG	PRTG	ENSG00000166450	-1.093578649814675	[40]	[57]	-7	hSpCas9	negative selection	12420154
55742856	55742879	15	+	28162770	OCIAML3	viability	GCAGCAGGAGCAGGAGCGCGCGG	PRTG	ENSG00000166450	-1.797541034409295	[37]	[32]	-8	hSpCas9	negative selection	12420155
55742825	55742848	15	+	28162770	OCIAML3	viability	AAAGCGCGCCCACCTGGCAAAGG	PRTG	ENSG00000166450	0.08406426478847462	[74]	[239]	0	hSpCas9	negative selection	12420156
55679307	55679330	15	-	28162770	OCIAML3	viability	GGAAGGAAGATACATTCGAATGG	PRTG	ENSG00000166450	0.5727708058012851	[50]	[228]	5	hSpCas9	negative selection	12420157
55677973	55677996	15	-	28162770	OCIAML3	viability	TGCATGGCTGAGAATAGCCAAGG	PRTG	ENSG00000166450	0.10765108510609034	[90]	[295]	1	hSpCas9	negative selection	12420158