Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:5664
• Symbol:PSEN2
• Description:presenilin 2

DataSource: http://genomecrispr.dkfz.de/#!/results/PSEN2

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
226883704	226883727	1	+	26472758	Jiyoye	viability	GAGAAGCCAGGAGAACGAGGAGG	PSEN2	ENSG00000143801	-1.224329705152313	[188]	[60]	-7	hSpCas9	negative selection	129438
226885554	226885577	1	+	26472758	Jiyoye	viability	ACTGAGGACACACCCTCGGTGGG	PSEN2	ENSG00000143801	0.200724504038447	[74]	[64]	1	hSpCas9	negative selection	129439
226883874	226883897	1	-	26472758	Jiyoye	viability	GAAGCGCACAGACTTGATGGTGG	PSEN2	ENSG00000143801	-0.12007162135899521	[146]	[101]	-1	hSpCas9	negative selection	129440
226882026	226882049	1	+	26472758	Jiyoye	viability	ATGGAGAGAACACTGCCCAGTGG	PSEN2	ENSG00000143801	1.6718786077002856	[71]	[172]	8	hSpCas9	negative selection	129441
226888867	226888890	1	-	26472758	Jiyoye	viability	CCAGACAGTCAGCAAGAGGGTGG	PSEN2	ENSG00000143801	0.17922343482752479	[129]	[110]	1	hSpCas9	negative selection	129442
226888919	226888942	1	-	26472758	Jiyoye	viability	GCACCAGAGGGCCCTTCCAGTGG	PSEN2	ENSG00000143801	-1.725274914517776	[170]	[38]	-8	hSpCas9	negative selection	129443
226890072	226890095	1	+	26472758	Jiyoye	viability	AATGCTGGTAGAAACTGCCCAGG	PSEN2	ENSG00000143801	0.8327821224949045	[101]	[136]	6	hSpCas9	negative selection	129444
226891315	226891338	1	-	26472758	Jiyoye	viability	GGAGGGCACCCTGAGAGGAGGGG	PSEN2	ENSG00000143801	-2.0221362487550882	[236]	[43]	-8	hSpCas9	negative selection	129445
226883716	226883739	1	+	26472758	Jiyoye	viability	GAACGAGGAGGACGGTGAGGAGG	PSEN2	ENSG00000143801	3.5771003829481853	[0]	[8]	9	hSpCas9	negative selection	129446
226883746	226883769	1	-	26472758	Jiyoye	viability	GAACCCCACTACAGACATAGCGG	PSEN2	ENSG00000143801	0.7677650967623408	[80]	[103]	5	hSpCas9	negative selection	129447
226883704	226883727	1	+	26472758	KBM7	viability	GAGAAGCCAGGAGAACGAGGAGG	PSEN2	ENSG00000143801	-1.1827014342509214	[545,485]	[148,68]	-7	hSpCas9	negative selection	320556
226885554	226885577	1	+	26472758	KBM7	viability	ACTGAGGACACACCCTCGGTGGG	PSEN2	ENSG00000143801	0.8610402510342424	[349,360]	[209,390]	8	hSpCas9	negative selection	320557
226883874	226883897	1	-	26472758	KBM7	viability	GAAGCGCACAGACTTGATGGTGG	PSEN2	ENSG00000143801	0.17685127788775473	[370,272]	[68,258]	1	hSpCas9	negative selection	320558
226882026	226882049	1	+	26472758	KBM7	viability	ATGGAGAGAACACTGCCCAGTGG	PSEN2	ENSG00000143801	0.8748247794967587	[488,306]	[330,341]	8	hSpCas9	negative selection	320559
226888867	226888890	1	-	26472758	KBM7	viability	CCAGACAGTCAGCAAGAGGGTGG	PSEN2	ENSG00000143801	-0.7257934096365906	[698,367]	[173,123]	-6	hSpCas9	negative selection	320560
226888919	226888942	1	-	26472758	KBM7	viability	GCACCAGAGGGCCCTTCCAGTGG	PSEN2	ENSG00000143801	-1.5070521626152202	[598,364]	[65,88]	-8	hSpCas9	negative selection	320561
226890072	226890095	1	+	26472758	KBM7	viability	AATGCTGGTAGAAACTGCCCAGG	PSEN2	ENSG00000143801	0.44836052346802546	[588,282]	[307,237]	5	hSpCas9	negative selection	320562
226891315	226891338	1	-	26472758	KBM7	viability	GGAGGGCACCCTGAGAGGAGGGG	PSEN2	ENSG00000143801	-0.66228520845897	[532,438]	[149,137]	-5	hSpCas9	negative selection	320563
226883716	226883739	1	+	26472758	KBM7	viability	GAACGAGGAGGACGGTGAGGAGG	PSEN2	ENSG00000143801	-0.0571295282604698	[25,36]	[3,23]	0	hSpCas9	negative selection	320564
226883746	226883769	1	-	26472758	KBM7	viability	GAACCCCACTACAGACATAGCGG	PSEN2	ENSG00000143801	0.5393166912479853	[402,444]	[318,268]	6	hSpCas9	negative selection	320565
226883704	226883727	1	+	26472758	Raji	viability	GAGAAGCCAGGAGAACGAGGAGG	PSEN2	ENSG00000143801	-2.0846352369193295	[328]	[17]	-8	hSpCas9	negative selection	511674
226885554	226885577	1	+	26472758	Raji	viability	ACTGAGGACACACCCTCGGTGGG	PSEN2	ENSG00000143801	0.13059092653492463	[184]	[46]	1	hSpCas9	negative selection	511675
226883874	226883897	1	-	26472758	Raji	viability	GAAGCGCACAGACTTGATGGTGG	PSEN2	ENSG00000143801	0.15417774685254063	[181]	[46]	1	hSpCas9	negative selection	511676
226882026	226882049	1	+	26472758	Raji	viability	ATGGAGAGAACACTGCCCAGTGG	PSEN2	ENSG00000143801	0.8409505530779409	[254]	[105]	7	hSpCas9	negative selection	511677
226888867	226888890	1	-	26472758	Raji	viability	CCAGACAGTCAGCAAGAGGGTGG	PSEN2	ENSG00000143801	-0.3413745817492455	[201]	[36]	-3	hSpCas9	negative selection	511678
226888919	226888942	1	-	26472758	Raji	viability	GCACCAGAGGGCCCTTCCAGTGG	PSEN2	ENSG00000143801	-1.365104236089144	[221]	[19]	-7	hSpCas9	negative selection	511679
226890072	226890095	1	+	26472758	Raji	viability	AATGCTGGTAGAAACTGCCCAGG	PSEN2	ENSG00000143801	0.7203604122643523	[237]	[90]	6	hSpCas9	negative selection	511680
226891315	226891338	1	-	26472758	Raji	viability	GGAGGGCACCCTGAGAGGAGGGG	PSEN2	ENSG00000143801	-0.7450592762125428	[194]	[26]	-5	hSpCas9	negative selection	511681
226883716	226883739	1	+	26472758	Raji	viability	GAACGAGGAGGACGGTGAGGAGG	PSEN2	ENSG00000143801	-2.846812775013276	[30]	[0]	-9	hSpCas9	negative selection	511682
226883746	226883769	1	-	26472758	Raji	viability	GAACCCCACTACAGACATAGCGG	PSEN2	ENSG00000143801	0.7252379176521304	[158]	[60]	6	hSpCas9	negative selection	511683
226883704	226883727	1	+	26472758	K562	viability	GAGAAGCCAGGAGAACGAGGAGG	PSEN2	ENSG00000143801	-1.9427842652077012	[377]	[82]	-7	hSpCas9	negative selection	702792
226885554	226885577	1	+	26472758	K562	viability	ACTGAGGACACACCCTCGGTGGG	PSEN2	ENSG00000143801	1.566346822553809	[289]	[724]	9	hSpCas9	negative selection	702793
226883874	226883897	1	-	26472758	K562	viability	GAAGCGCACAGACTTGATGGTGG	PSEN2	ENSG00000143801	0.31000706929402355	[300]	[314]	2	hSpCas9	negative selection	702794
226882026	226882049	1	+	26472758	K562	viability	ATGGAGAGAACACTGCCCAGTGG	PSEN2	ENSG00000143801	0.5397350923064894	[382]	[469]	4	hSpCas9	negative selection	702795
226888867	226888890	1	-	26472758	K562	viability	CCAGACAGTCAGCAAGAGGGTGG	PSEN2	ENSG00000143801	-2.9525364797450138	[430]	[46]	-8	hSpCas9	negative selection	702796
226888919	226888942	1	-	26472758	K562	viability	GCACCAGAGGGCCCTTCCAGTGG	PSEN2	ENSG00000143801	-2.283318904361759	[345]	[59]	-8	hSpCas9	negative selection	702797
226890072	226890095	1	+	26472758	K562	viability	AATGCTGGTAGAAACTGCCCAGG	PSEN2	ENSG00000143801	-0.15193420834747018	[357]	[271]	-1	hSpCas9	negative selection	702798
226891315	226891338	1	-	26472758	K562	viability	GGAGGGCACCCTGAGAGGAGGGG	PSEN2	ENSG00000143801	-0.9322636399511741	[320]	[141]	-5	hSpCas9	negative selection	702799
226883716	226883739	1	+	26472758	K562	viability	GAACGAGGAGGACGGTGAGGAGG	PSEN2	ENSG00000143801	-5.040983491195801	[38]	[0]	-9	hSpCas9	negative selection	702800
226883746	226883769	1	-	26472758	K562	viability	GAACCCCACTACAGACATAGCGG	PSEN2	ENSG00000143801	0.33653692965487825	[454]	[484]	2	hSpCas9	negative selection	702801
226881916	226881939	1	+	26627737	DLD1	viability	ATTCATGGCCTCTGACAGCGAGG	PSEN2	ENSG00000143801	-0.5018295300104989	[506]	[83,163,92]	-5	hSpCas9	negative selection	769428
226883891	226883914	1	+	26627737	DLD1	viability	CGCTTCTACACAGAGAAGAATGG	PSEN2	ENSG00000143801	0.5042152340830378	[716]	[237,404,314]	5	hSpCas9	negative selection	769429
226885594	226885617	1	-	26627737	DLD1	viability	CATGATGAGGGTGTTCAGCACGG	PSEN2	ENSG00000143801	-0.05437544549543327	[1159]	[499,257,293]	0	hSpCas9	negative selection	769430
226888096	226888119	1	-	26627737	DLD1	viability	AAGACATGATCAACCAGCCATGG	PSEN2	ENSG00000143801	0.2818816651138174	[461]	[185,75,248]	3	hSpCas9	negative selection	769431
226888838	226888861	1	+	26627737	DLD1	viability	CAAGACCTACAATGTGGCCATGG	PSEN2	ENSG00000143801	-0.263376437988306	[970]	[147,440,187]	-3	hSpCas9	negative selection	769432
226890072	226890095	1	+	26627737	DLD1	viability	AATGCTGGTAGAAACTGCCCAGG	PSEN2	ENSG00000143801	5.268302783106524	[3]	[49,89,11]	9	hSpCas9	negative selection	769433
226881916	226881939	1	+	26627737	GBM cells	viability after 5 days	ATTCATGGCCTCTGACAGCGAGG	PSEN2	ENSG00000143801	-0.48531757761198346	[277]	[76,135]	-6	hSpCas9	negative selection	851743
226883891	226883914	1	+	26627737	GBM cells	viability after 5 days	CGCTTCTACACAGAGAAGAATGG	PSEN2	ENSG00000143801	-0.06795934550571969	[817]	[376,459]	-1	hSpCas9	negative selection	851744
226885594	226885617	1	-	26627737	GBM cells	viability after 5 days	CATGATGAGGGTGTTCAGCACGG	PSEN2	ENSG00000143801	0.6188059556929504	[339]	[294,264]	8	hSpCas9	negative selection	851745
226888096	226888119	1	-	26627737	GBM cells	viability after 5 days	AAGACATGATCAACCAGCCATGG	PSEN2	ENSG00000143801	0.4447379816998836	[273]	[185,213]	6	hSpCas9	negative selection	851746
226888838	226888861	1	+	26627737	GBM cells	viability after 5 days	CAAGACCTACAATGTGGCCATGG	PSEN2	ENSG00000143801	0.3929796203297999	[332]	[245,222]	6	hSpCas9	negative selection	851747
226890072	226890095	1	+	26627737	GBM cells	viability after 5 days	AATGCTGGTAGAAACTGCCCAGG	PSEN2	ENSG00000143801	-0.48810924822356183	[67]	[18,32]	-6	hSpCas9	negative selection	851748
226881916	226881939	1	+	26627737	GBM cells	viability after 13 days	ATTCATGGCCTCTGACAGCGAGG	PSEN2	ENSG00000143801	0.10484438008334565	[277]	[159,163]	1	hSpCas9	negative selection	934058
226883891	226883914	1	+	26627737	GBM cells	viability after 13 days	CGCTTCTACACAGAGAAGAATGG	PSEN2	ENSG00000143801	0.12239878944890825	[817]	[604,383]	1	hSpCas9	negative selection	934059
226885594	226885617	1	-	26627737	GBM cells	viability after 13 days	CATGATGAGGGTGTTCAGCACGG	PSEN2	ENSG00000143801	0.5657024535192035	[339]	[368,194]	7	hSpCas9	negative selection	934060
226888096	226888119	1	-	26627737	GBM cells	viability after 13 days	AAGACATGATCAACCAGCCATGG	PSEN2	ENSG00000143801	0.6663994100599597	[273]	[273,204]	7	hSpCas9	negative selection	934061
226888838	226888861	1	+	26627737	GBM cells	viability after 13 days	CAAGACCTACAATGTGGCCATGG	PSEN2	ENSG00000143801	0.31980246141122765	[332]	[294,168]	4	hSpCas9	negative selection	934062
226890072	226890095	1	+	26627737	GBM cells	viability after 13 days	AATGCTGGTAGAAACTGCCCAGG	PSEN2	ENSG00000143801	-0.6107057939721572	[67]	[0,42]	-6	hSpCas9	negative selection	934063
226881916	226881939	1	+	26627737	GBM cells	viability after 21 days	ATTCATGGCCTCTGACAGCGAGG	PSEN2	ENSG00000143801	-0.3534859370603397	[277]	[124,111]	-3	hSpCas9	negative selection	1016373
226883891	226883914	1	+	26627737	GBM cells	viability after 21 days	CGCTTCTACACAGAGAAGAATGG	PSEN2	ENSG00000143801	0.1464323344129188	[817]	[482,499]	1	hSpCas9	negative selection	1016374
226885594	226885617	1	-	26627737	GBM cells	viability after 21 days	CATGATGAGGGTGTTCAGCACGG	PSEN2	ENSG00000143801	0.35199032151471893	[339]	[217,251]	3	hSpCas9	negative selection	1016375
226888096	226888119	1	-	26627737	GBM cells	viability after 21 days	AAGACATGATCAACCAGCCATGG	PSEN2	ENSG00000143801	0.6796433472342287	[273]	[239,236]	7	hSpCas9	negative selection	1016376
226888838	226888861	1	+	26627737	GBM cells	viability after 21 days	CAAGACCTACAATGTGGCCATGG	PSEN2	ENSG00000143801	0.2972190706840238	[332]	[226,217]	3	hSpCas9	negative selection	1016377
226890072	226890095	1	+	26627737	GBM cells	viability after 21 days	AATGCTGGTAGAAACTGCCCAGG	PSEN2	ENSG00000143801	0.16549044380928546	[67]	[42,39]	1	hSpCas9	negative selection	1016378
226881916	226881939	1	+	26627737	RPE1	viability after 9 days	ATTCATGGCCTCTGACAGCGAGG	PSEN2	ENSG00000143801	0.41073057245491684	[664]	[126,469]	3	hSpCas9	negative selection	1098688
226883891	226883914	1	+	26627737	RPE1	viability after 9 days	CGCTTCTACACAGAGAAGAATGG	PSEN2	ENSG00000143801	1.1162913209761895	[1539]	[925,1198]	6	hSpCas9	negative selection	1098689
226885594	226885617	1	-	26627737	RPE1	viability after 9 days	CATGATGAGGGTGTTCAGCACGG	PSEN2	ENSG00000143801	-0.04659463325500712	[1907]	[473,712]	0	hSpCas9	negative selection	1098690
226888096	226888119	1	-	26627737	RPE1	viability after 9 days	AAGACATGATCAACCAGCCATGG	PSEN2	ENSG00000143801	0.24482714985600645	[707]	[118,447]	1	hSpCas9	negative selection	1098691
226888838	226888861	1	+	26627737	RPE1	viability after 9 days	CAAGACCTACAATGTGGCCATGG	PSEN2	ENSG00000143801	0.7891139708060342	[750]	[359,465]	5	hSpCas9	negative selection	1098692
226890072	226890095	1	+	26627737	RPE1	viability after 9 days	AATGCTGGTAGAAACTGCCCAGG	PSEN2	ENSG00000143801	-2.513022587262669	[471]	[0,57]	-9	hSpCas9	negative selection	1098693
226881916	226881939	1	+	26627737	RPE1	viability after 12 days	ATTCATGGCCTCTGACAGCGAGG	PSEN2	ENSG00000143801	-0.05411559207738778	[664]	[157,186]	0	hSpCas9	negative selection	1181003
226883891	226883914	1	+	26627737	RPE1	viability after 12 days	CGCTTCTACACAGAGAAGAATGG	PSEN2	ENSG00000143801	1.3379850959242967	[1539]	[992,1101]	7	hSpCas9	negative selection	1181004
226885594	226885617	1	-	26627737	RPE1	viability after 12 days	CATGATGAGGGTGTTCAGCACGG	PSEN2	ENSG00000143801	0.16640079055577606	[1907]	[567,582]	1	hSpCas9	negative selection	1181005
226888096	226888119	1	-	26627737	RPE1	viability after 12 days	AAGACATGATCAACCAGCCATGG	PSEN2	ENSG00000143801	0.08630916919679063	[707]	[148,257]	0	hSpCas9	negative selection	1181006
226888838	226888861	1	+	26627737	RPE1	viability after 12 days	CAAGACCTACAATGTGGCCATGG	PSEN2	ENSG00000143801	1.252821129253944	[750]	[457,504]	7	hSpCas9	negative selection	1181007
226890072	226890095	1	+	26627737	RPE1	viability after 12 days	AATGCTGGTAGAAACTGCCCAGG	PSEN2	ENSG00000143801	-3.0714205352752164	[471]	[0,29]	-9	hSpCas9	negative selection	1181008
226881916	226881939	1	+	26627737	RPE1	viability after 15 days	ATTCATGGCCTCTGACAGCGAGG	PSEN2	ENSG00000143801	-0.7993959631559078	[664]	[74,139]	-5	hSpCas9	negative selection	1263318
226883891	226883914	1	+	26627737	RPE1	viability after 15 days	CGCTTCTACACAGAGAAGAATGG	PSEN2	ENSG00000143801	1.3190173136866528	[1539]	[1233,944]	7	hSpCas9	negative selection	1263319
226885594	226885617	1	-	26627737	RPE1	viability after 15 days	CATGATGAGGGTGTTCAGCACGG	PSEN2	ENSG00000143801	0.04900710962518495	[1907]	[536,578]	0	hSpCas9	negative selection	1263320
226888096	226888119	1	-	26627737	RPE1	viability after 15 days	AAGACATGATCAACCAGCCATGG	PSEN2	ENSG00000143801	0.1978725703151034	[707]	[132,322]	1	hSpCas9	negative selection	1263321
226888838	226888861	1	+	26627737	RPE1	viability after 15 days	CAAGACCTACAATGTGGCCATGG	PSEN2	ENSG00000143801	1.4260722566440636	[750]	[409,725]	7	hSpCas9	negative selection	1263322
226890072	226890095	1	+	26627737	RPE1	viability after 15 days	AATGCTGGTAGAAACTGCCCAGG	PSEN2	ENSG00000143801	-2.8269492182007725	[471]	[0,35]	-9	hSpCas9	negative selection	1263323
226881916	226881939	1	+	26627737	RPE1	viability after 18 days	ATTCATGGCCTCTGACAGCGAGG	PSEN2	ENSG00000143801	-0.0022757039854002237	[664]	[198,157]	0	hSpCas9	negative selection	1345633
226883891	226883914	1	+	26627737	RPE1	viability after 18 days	CGCTTCTACACAGAGAAGAATGG	PSEN2	ENSG00000143801	1.4074328390573214	[1539]	[1187,1010]	7	hSpCas9	negative selection	1345634
226885594	226885617	1	-	26627737	RPE1	viability after 18 days	CATGATGAGGGTGTTCAGCACGG	PSEN2	ENSG00000143801	0.07596366527476128	[1907]	[447,643]	0	hSpCas9	negative selection	1345635
226888096	226888119	1	-	26627737	RPE1	viability after 18 days	AAGACATGATCAACCAGCCATGG	PSEN2	ENSG00000143801	0.6144607116885068	[707]	[263,322]	4	hSpCas9	negative selection	1345636
226888838	226888861	1	+	26627737	RPE1	viability after 18 days	CAAGACCTACAATGTGGCCATGG	PSEN2	ENSG00000143801	1.3871315014434387	[750]	[401,666]	7	hSpCas9	negative selection	1345637
226890072	226890095	1	+	26627737	RPE1	viability after 18 days	AATGCTGGTAGAAACTGCCCAGG	PSEN2	ENSG00000143801	-2.717247449947625	[471]	[0,38]	-9	hSpCas9	negative selection	1345638
226881916	226881939	1	+	26627737	HeLa	viability after 8 days	ATTCATGGCCTCTGACAGCGAGG	PSEN2	ENSG00000143801	-0.022779183775477663	[304]	[182,112,108]	0	hSpCas9	negative selection	1427948
226883891	226883914	1	+	26627737	HeLa	viability after 8 days	CGCTTCTACACAGAGAAGAATGG	PSEN2	ENSG00000143801	-0.35242927368477783	[1400]	[689,470,328]	-3	hSpCas9	negative selection	1427949
226885594	226885617	1	-	26627737	HeLa	viability after 8 days	CATGATGAGGGTGTTCAGCACGG	PSEN2	ENSG00000143801	0.66507549255193	[645]	[444,549,348]	6	hSpCas9	negative selection	1427950
226888096	226888119	1	-	26627737	HeLa	viability after 8 days	AAGACATGATCAACCAGCCATGG	PSEN2	ENSG00000143801	0.444785893116559	[375]	[259,218,198]	4	hSpCas9	negative selection	1427951
226888838	226888861	1	+	26627737	HeLa	viability after 8 days	CAAGACCTACAATGTGGCCATGG	PSEN2	ENSG00000143801	0.9491549818048377	[329]	[124,288,376]	7	hSpCas9	negative selection	1427952
226890072	226890095	1	+	26627737	HeLa	viability after 8 days	AATGCTGGTAGAAACTGCCCAGG	PSEN2	ENSG00000143801	-0.9992569897872627	[73]	[24,4,19]	-7	hSpCas9	negative selection	1427953
226881916	226881939	1	+	26627737	HeLa	viability after 12 days	ATTCATGGCCTCTGACAGCGAGG	PSEN2	ENSG00000143801	0.7485615179114634	[304]	[280,195,161]	6	hSpCas9	negative selection	1510263
226883891	226883914	1	+	26627737	HeLa	viability after 12 days	CGCTTCTACACAGAGAAGAATGG	PSEN2	ENSG00000143801	-0.5585097484919306	[1400]	[426,358,397]	-5	hSpCas9	negative selection	1510264
226885594	226885617	1	-	26627737	HeLa	viability after 12 days	CATGATGAGGGTGTTCAGCACGG	PSEN2	ENSG00000143801	0.6836277986875858	[645]	[364,499,411]	5	hSpCas9	negative selection	1510265
226888096	226888119	1	-	26627737	HeLa	viability after 12 days	AAGACATGATCAACCAGCCATGG	PSEN2	ENSG00000143801	-0.4383255597400961	[375]	[50,87,205]	-4	hSpCas9	negative selection	1510266
226888838	226888861	1	+	26627737	HeLa	viability after 12 days	CAAGACCTACAATGTGGCCATGG	PSEN2	ENSG00000143801	1.2149177067239043	[329]	[672,52,261]	8	hSpCas9	negative selection	1510267
226890072	226890095	1	+	26627737	HeLa	viability after 12 days	AATGCTGGTAGAAACTGCCCAGG	PSEN2	ENSG00000143801	0.2204966850129959	[73]	[84,0,25]	2	hSpCas9	negative selection	1510268
226881916	226881939	1	+	26627737	HeLa	viability after 15 days	ATTCATGGCCTCTGACAGCGAGG	PSEN2	ENSG00000143801	0.5235646373871605	[304]	[107,338,81]	4	hSpCas9	negative selection	1592578
226883891	226883914	1	+	26627737	HeLa	viability after 15 days	CGCTTCTACACAGAGAAGAATGG	PSEN2	ENSG00000143801	-0.6200063805225697	[1400]	[410,412,281]	-5	hSpCas9	negative selection	1592579
226885594	226885617	1	-	26627737	HeLa	viability after 15 days	CATGATGAGGGTGTTCAGCACGG	PSEN2	ENSG00000143801	0.9659900810173596	[645]	[388,576,581]	7	hSpCas9	negative selection	1592580
226888096	226888119	1	-	26627737	HeLa	viability after 15 days	AAGACATGATCAACCAGCCATGG	PSEN2	ENSG00000143801	-0.4918245257580771	[375]	[17,100,216]	-4	hSpCas9	negative selection	1592581
226888838	226888861	1	+	26627737	HeLa	viability after 15 days	CAAGACCTACAATGTGGCCATGG	PSEN2	ENSG00000143801	1.7717833237903897	[329]	[724,198,447]	9	hSpCas9	negative selection	1592582
226890072	226890095	1	+	26627737	HeLa	viability after 15 days	AATGCTGGTAGAAACTGCCCAGG	PSEN2	ENSG00000143801	-1.0953928712122893	[73]	[36,2,0]	-7	hSpCas9	negative selection	1592583
226881916	226881939	1	+	26627737	HeLa	viability after 18 days	ATTCATGGCCTCTGACAGCGAGG	PSEN2	ENSG00000143801	0.5167962338439098	[304]	[68,282,81]	4	hSpCas9	negative selection	1674893
226883891	226883914	1	+	26627737	HeLa	viability after 18 days	CGCTTCTACACAGAGAAGAATGG	PSEN2	ENSG00000143801	-0.5937602950162975	[1400]	[292,336,281]	-5	hSpCas9	negative selection	1674894
226885594	226885617	1	-	26627737	HeLa	viability after 18 days	CATGATGAGGGTGTTCAGCACGG	PSEN2	ENSG00000143801	0.9575585234238313	[645]	[250,482,581]	7	hSpCas9	negative selection	1674895
226888096	226888119	1	-	26627737	HeLa	viability after 18 days	AAGACATGATCAACCAGCCATGG	PSEN2	ENSG00000143801	-0.4957947185448661	[375]	[15,77,216]	-4	hSpCas9	negative selection	1674896
226888838	226888861	1	+	26627737	HeLa	viability after 18 days	CAAGACCTACAATGTGGCCATGG	PSEN2	ENSG00000143801	1.7826179658328947	[329]	[492,164,447]	9	hSpCas9	negative selection	1674897
226890072	226890095	1	+	26627737	HeLa	viability after 18 days	AATGCTGGTAGAAACTGCCCAGG	PSEN2	ENSG00000143801	-1.0142376167696847	[73]	[25,2,0]	-7	hSpCas9	negative selection	1674898
226881916	226881939	1	+	26627737	HCT116	viability after 6 days	ATTCATGGCCTCTGACAGCGAGG	PSEN2	ENSG00000143801	1.1598700873937604	[284]	[248,17]	6	hSpCas9	negative selection	1757208
226883891	226883914	1	+	26627737	HCT116	viability after 6 days	CGCTTCTACACAGAGAAGAATGG	PSEN2	ENSG00000143801	-0.23222373334344992	[1426]	[170,201]	-1	hSpCas9	negative selection	1757209
226885594	226885617	1	-	26627737	HCT116	viability after 6 days	CATGATGAGGGTGTTCAGCACGG	PSEN2	ENSG00000143801	0.4042973441984463	[1802]	[436,340]	2	hSpCas9	negative selection	1757210
226888096	226888119	1	-	26627737	HCT116	viability after 6 days	AAGACATGATCAACCAGCCATGG	PSEN2	ENSG00000143801	-0.7200453873384066	[888]	[89,81]	-4	hSpCas9	negative selection	1757211
226888838	226888861	1	+	26627737	HCT116	viability after 6 days	CAAGACCTACAATGTGGCCATGG	PSEN2	ENSG00000143801	0.6084686941171803	[1143]	[415,195]	3	hSpCas9	negative selection	1757212
226890072	226890095	1	+	26627737	HCT116	viability after 6 days	AATGCTGGTAGAAACTGCCCAGG	PSEN2	ENSG00000143801	0.7625250490573494	[10]	[0,3]	4	hSpCas9	negative selection	1757213
226881916	226881939	1	+	26627737	HCT116	viability after 8 days	ATTCATGGCCTCTGACAGCGAGG	PSEN2	ENSG00000143801	0.13545946219802166	[248]	[269,93,90]	1	hSpCas9	negative selection	1839523
226883891	226883914	1	+	26627737	HCT116	viability after 8 days	CGCTTCTACACAGAGAAGAATGG	PSEN2	ENSG00000143801	0.19171127819759026	[787]	[413,469,600]	2	hSpCas9	negative selection	1839524
226885594	226885617	1	-	26627737	HCT116	viability after 8 days	CATGATGAGGGTGTTCAGCACGG	PSEN2	ENSG00000143801	-0.0968527586346456	[531]	[259,280,280]	-1	hSpCas9	negative selection	1839525
226888096	226888119	1	-	26627737	HCT116	viability after 8 days	AAGACATGATCAACCAGCCATGG	PSEN2	ENSG00000143801	0.03941003590287967	[413]	[210,264,226]	0	hSpCas9	negative selection	1839526
226888838	226888861	1	+	26627737	HCT116	viability after 8 days	CAAGACCTACAATGTGGCCATGG	PSEN2	ENSG00000143801	-0.05361986855646439	[565]	[311,312,276]	0	hSpCas9	negative selection	1839527
226890072	226890095	1	+	26627737	HCT116	viability after 8 days	AATGCTGGTAGAAACTGCCCAGG	PSEN2	ENSG00000143801	1.0209603342178606	[25]	[11,52,21]	8	hSpCas9	negative selection	1839528
226881916	226881939	1	+	26627737	HCT116	viability after 9 days	ATTCATGGCCTCTGACAGCGAGG	PSEN2	ENSG00000143801	0.6329248936673735	[284]	[260,4]	4	hSpCas9	negative selection	1921838
226883891	226883914	1	+	26627737	HCT116	viability after 9 days	CGCTTCTACACAGAGAAGAATGG	PSEN2	ENSG00000143801	0.26528208159241107	[1426]	[424,483]	2	hSpCas9	negative selection	1921839
226885594	226885617	1	-	26627737	HCT116	viability after 9 days	CATGATGAGGGTGTTCAGCACGG	PSEN2	ENSG00000143801	-1.274177425784611	[1802]	[250,157]	-7	hSpCas9	negative selection	1921840
226888096	226888119	1	-	26627737	HCT116	viability after 9 days	AAGACATGATCAACCAGCCATGG	PSEN2	ENSG00000143801	0.14994330704000114	[888]	[316,220]	1	hSpCas9	negative selection	1921841
226888838	226888861	1	+	26627737	HCT116	viability after 9 days	CAAGACCTACAATGTGGCCATGG	PSEN2	ENSG00000143801	-0.23336378315204898	[1143]	[370,171]	-2	hSpCas9	negative selection	1921842
226890072	226890095	1	+	26627737	HCT116	viability after 9 days	AATGCTGGTAGAAACTGCCCAGG	PSEN2	ENSG00000143801	3.226208790944722	[10]	[60,0]	9	hSpCas9	negative selection	1921843
226881916	226881939	1	+	26627737	HCT116	viability after 12 days	ATTCATGGCCTCTGACAGCGAGG	PSEN2	ENSG00000143801	0.18119435533581574	[248]	[256,83,92]	2	hSpCas9	negative selection	2004153
226883891	226883914	1	+	26627737	HCT116	viability after 12 days	CGCTTCTACACAGAGAAGAATGG	PSEN2	ENSG00000143801	-0.18763711545963813	[787]	[355,342,391]	-2	hSpCas9	negative selection	2004154
226885594	226885617	1	-	26627737	HCT116	viability after 12 days	CATGATGAGGGTGTTCAGCACGG	PSEN2	ENSG00000143801	0.645800954095534	[531]	[379,381,553]	6	hSpCas9	negative selection	2004155
226888096	226888119	1	-	26627737	HCT116	viability after 12 days	AAGACATGATCAACCAGCCATGG	PSEN2	ENSG00000143801	-0.10386553373645141	[413]	[213,187,203]	-1	hSpCas9	negative selection	2004156
226888838	226888861	1	+	26627737	HCT116	viability after 12 days	CAAGACCTACAATGTGGCCATGG	PSEN2	ENSG00000143801	0.031326333451204835	[565]	[304,227,376]	0	hSpCas9	negative selection	2004157
226890072	226890095	1	+	26627737	HCT116	viability after 12 days	AATGCTGGTAGAAACTGCCCAGG	PSEN2	ENSG00000143801	0.6930415046051519	[25]	[28,35,0]	6	hSpCas9	negative selection	2004158
226881916	226881939	1	+	26627737	HCT116	viability after 15 days	ATTCATGGCCTCTGACAGCGAGG	PSEN2	ENSG00000143801	0.2994155460750765	[248]	[205,99,224]	3	hSpCas9	negative selection	2086468
226883891	226883914	1	+	26627737	HCT116	viability after 15 days	CGCTTCTACACAGAGAAGAATGG	PSEN2	ENSG00000143801	0.2931742226215508	[787]	[915,274,516]	3	hSpCas9	negative selection	2086469
226885594	226885617	1	-	26627737	HCT116	viability after 15 days	CATGATGAGGGTGTTCAGCACGG	PSEN2	ENSG00000143801	0.5188173390493084	[531]	[329,437,530]	5	hSpCas9	negative selection	2086470
226888096	226888119	1	-	26627737	HCT116	viability after 15 days	AAGACATGATCAACCAGCCATGG	PSEN2	ENSG00000143801	-0.2855247656938985	[413]	[282,125,186]	-3	hSpCas9	negative selection	2086471
226888838	226888861	1	+	26627737	HCT116	viability after 15 days	CAAGACCTACAATGTGGCCATGG	PSEN2	ENSG00000143801	-0.247116292401247	[565]	[310,227,286]	-3	hSpCas9	negative selection	2086472
226890072	226890095	1	+	26627737	HCT116	viability after 15 days	AATGCTGGTAGAAACTGCCCAGG	PSEN2	ENSG00000143801	0.9997245886885366	[25]	[41,14,33]	8	hSpCas9	negative selection	2086473
226881916	226881939	1	+	26627737	HCT116	viability after 18 days	ATTCATGGCCTCTGACAGCGAGG	PSEN2	ENSG00000143801	0.18214476584194778	[248]	[283,30,99]	1	hSpCas9	negative selection	2168783
226883891	226883914	1	+	26627737	HCT116	viability after 18 days	CGCTTCTACACAGAGAAGAATGG	PSEN2	ENSG00000143801	-0.1649651684507456	[787]	[317,334,367]	-1	hSpCas9	negative selection	2168784
226885594	226885617	1	-	26627737	HCT116	viability after 18 days	CATGATGAGGGTGTTCAGCACGG	PSEN2	ENSG00000143801	1.2514370479483783	[531]	[536,548,761]	8	hSpCas9	negative selection	2168785
226888096	226888119	1	-	26627737	HCT116	viability after 18 days	AAGACATGATCAACCAGCCATGG	PSEN2	ENSG00000143801	0.20995905346056482	[413]	[143,228,325]	1	hSpCas9	negative selection	2168786
226888838	226888861	1	+	26627737	HCT116	viability after 18 days	CAAGACCTACAATGTGGCCATGG	PSEN2	ENSG00000143801	0.0574792401612052	[565]	[232,196,436]	0	hSpCas9	negative selection	2168787
226890072	226890095	1	+	26627737	HCT116	viability after 18 days	AATGCTGGTAGAAACTGCCCAGG	PSEN2	ENSG00000143801	-0.3991804384279045	[25]	[0,0,27]	-4	hSpCas9	negative selection	2168788
226881916	226881939	1	+	24336569	HL60	viability	ATTCATGGCCTCTGACAGCGAGG	PSEN2	ENSG00000143801	0.5291343270791091	[501]	[1532]	5	hSpCas9	negative selection	2286902
226881924	226881947	1	-	24336569	HL60	viability	CACTTCTTCCTCGCTGTCAGAGG	PSEN2	ENSG00000143801	-0.24471085578409135	[228]	[408]	-2	hSpCas9	negative selection	2286903
226881936	226881959	1	+	24336569	HL60	viability	AGGAAGAAGTGTGTGATGAGCGG	PSEN2	ENSG00000143801	1.1254982801379456	[234]	[1084]	8	hSpCas9	negative selection	2286904
226881952	226881975	1	+	24336569	HL60	viability	TGAGCGGACGTCCCTAATGTCGG	PSEN2	ENSG00000143801	0.09576866155491678	[546]	[1236]	0	hSpCas9	negative selection	2286905
226881983	226882006	1	-	24336569	HL60	viability	TCCTGGCAGGAGCGCGGCGTGGG	PSEN2	ENSG00000143801	1.2297375876654075	[134]	[669]	8	hSpCas9	negative selection	2286906
226881989	226882012	1	-	24336569	HL60	viability	CTGCCCTCCTGGCAGGAGCGCGG	PSEN2	ENSG00000143801	-0.41626754060788446	[407]	[646]	-4	hSpCas9	negative selection	2286907
226881994	226882017	1	+	24336569	HL60	viability	CTCCTGCCAGGAGGGCAGGCAGG	PSEN2	ENSG00000143801	-2.000240305354924	[258]	[136]	-9	hSpCas9	negative selection	2286908
226882003	226882026	1	+	24336569	HL60	viability	GGAGGGCAGGCAGGGCCCAGAGG	PSEN2	ENSG00000143801	-1.090528183057133	[478]	[475]	-7	hSpCas9	negative selection	2286909
226882018	226882041	1	-	24336569	HL60	viability	CAGTGTTCTCTCCATCCTCTGGG	PSEN2	ENSG00000143801	-0.2963496706376371	[606]	[1045]	-3	hSpCas9	negative selection	2286910
226882026	226882049	1	+	24336569	HL60	viability	ATGGAGAGAACACTGCCCAGTGG	PSEN2	ENSG00000143801	0.6652280395220835	[339]	[1140]	5	hSpCas9	negative selection	2286911
226881916	226881939	1	+	24336569	KBM7	viability	ATTCATGGCCTCTGACAGCGAGG	PSEN2	ENSG00000143801	0.6537364834473178	[566]	[2432]	6	hSpCas9	negative selection	2354079
226881924	226881947	1	-	24336569	KBM7	viability	CACTTCTTCCTCGCTGTCAGAGG	PSEN2	ENSG00000143801	1.1057951922723317	[176]	[1038]	8	hSpCas9	negative selection	2354080
226881936	226881959	1	+	24336569	KBM7	viability	AGGAAGAAGTGTGTGATGAGCGG	PSEN2	ENSG00000143801	-0.11462407951249624	[390]	[984]	-1	hSpCas9	negative selection	2354081
226881952	226881975	1	+	24336569	KBM7	viability	TGAGCGGACGTCCCTAATGTCGG	PSEN2	ENSG00000143801	-0.32924592754384197	[426]	[926]	-3	hSpCas9	negative selection	2354082
226881983	226882006	1	-	24336569	KBM7	viability	TCCTGGCAGGAGCGCGGCGTGGG	PSEN2	ENSG00000143801	-0.08410883941833669	[88]	[228]	0	hSpCas9	negative selection	2354083
226881989	226882012	1	-	24336569	KBM7	viability	CTGCCCTCCTGGCAGGAGCGCGG	PSEN2	ENSG00000143801	1.1184489462658542	[293]	[1740]	8	hSpCas9	negative selection	2354084
226881994	226882017	1	+	24336569	KBM7	viability	CTCCTGCCAGGAGGGCAGGCAGG	PSEN2	ENSG00000143801	0.20750939056291595	[173]	[547]	2	hSpCas9	negative selection	2354085
226882003	226882026	1	+	24336569	KBM7	viability	GGAGGGCAGGCAGGGCCCAGAGG	PSEN2	ENSG00000143801	-2.420842814076755	[694]	[353]	-8	hSpCas9	negative selection	2354086
226882018	226882041	1	-	24336569	KBM7	viability	CAGTGTTCTCTCCATCCTCTGGG	PSEN2	ENSG00000143801	-1.2983409061216862	[678]	[752]	-7	hSpCas9	negative selection	2354087
226882026	226882049	1	+	24336569	KBM7	viability	ATGGAGAGAACACTGCCCAGTGG	PSEN2	ENSG00000143801	0.1594770750228903	[431]	[1315]	1	hSpCas9	negative selection	2354088
226884835	226884858	1	-	25494202	A375	resistance to PLX-4720 (puromycin)	TCACTGCAGCCTCGACTTCTGGG	PSEN2	ENSG00000143801	-0.3334344553746127	[914,176]	[125,59]	-1	dCas9-VP64	positive selection	2383766
226870401	226870424	1	-	25494202	A375	resistance to PLX-4720 (puromycin)	CCTTAGAAGGAGTGGAGGCCGGG	PSEN2	ENSG00000143801	-2.9599959871179795	[305,32]	[5,1]	-9	dCas9-VP64	positive selection	2384022
226870425	226870448	1	+	25494202	A375	resistance to PLX-4720 (puromycin)	CGTCGCTTAGTTCCGACGTCGGG	PSEN2	ENSG00000143801	2.2550078553699837	[34,39]	[18,61]	7	dCas9-VP64	positive selection	2384023
226870453	226870476	1	-	25494202	A375	resistance to PLX-4720 (puromycin)	CTTCACGCCGCGTGGATGACAGG	PSEN2	ENSG00000143801	-0.033851734106017606	[5,31]	[0,6]	0	dCas9-VP64	positive selection	2384024
226884835	226884858	1	-	25494202	A375	resistance to PLX-4720 (zeocin)	TCACTGCAGCCTCGACTTCTGGG	PSEN2	ENSG00000143801	-0.34054073104189286	[370,392]	[107,88]	-3	dCas9-VP64	positive selection	2479021
226870401	226870424	1	-	25494202	A375	resistance to PLX-4720 (zeocin)	CCTTAGAAGGAGTGGAGGCCGGG	PSEN2	ENSG00000143801	-0.2160261772066231	[79,52]	[16,18]	-2	dCas9-VP64	positive selection	2479277
226870425	226870448	1	+	25494202	A375	resistance to PLX-4720 (zeocin)	CGTCGCTTAGTTCCGACGTCGGG	PSEN2	ENSG00000143801	-0.2116324272541188	[11,67]	[7,13]	-2	dCas9-VP64	positive selection	2479278
226870453	226870476	1	-	25494202	A375	resistance to PLX-4720 (zeocin)	CTTCACGCCGCGTGGATGACAGG	PSEN2	ENSG00000143801	-1.0784731755910302	[112,69]	[14,12]	-8	dCas9-VP64	positive selection	2479279
226885659	226885682	1	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CTACAAGTACCGCTGCTACAAGG	PSEN2	ENSG00000143801	0.07288249190718538	[5,5]	[4,4]	1	hSpCas9	positive selection	3014221
226888878	226888901	1	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCTGACTGTCTGGAACTTCGGGG	PSEN2	ENSG00000143801	-0.010647175107206391	[3,3]	[2,3]	0	hSpCas9	positive selection	3014222
226883755	226883778	1	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TCTGTAGTGGGGTTCCCGGGCGG	PSEN2	ENSG00000143801	-0.13463457714819535	[3,3]	[1,3]	-2	hSpCas9	positive selection	3014223
226883744	226883767	1	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TGACCGCTATGTCTGTAGTGGGG	PSEN2	ENSG00000143801	0.1524931303541458	[5,5]	[4,4]	3	hSpCas9	positive selection	3014224
226885659	226885682	1	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CTACAAGTACCGCTGCTACAAGG	PSEN2	ENSG00000143801	0.14646608195128724	[5,5]	[6,2]	2	hSpCas9	positive selection	3082079
226888878	226888901	1	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCTGACTGTCTGGAACTTCGGGG	PSEN2	ENSG00000143801	-0.27939573584901956	[3,3]	[3,0]	-4	hSpCas9	positive selection	3082080
226883755	226883778	1	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TCTGTAGTGGGGTTCCCGGGCGG	PSEN2	ENSG00000143801	-0.011038107485599566	[3,3]	[2,2]	0	hSpCas9	positive selection	3082081
226883744	226883767	1	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TGACCGCTATGTCTGTAGTGGGG	PSEN2	ENSG00000143801	0.44748746645065723	[5,5]	[8,2]	7	hSpCas9	positive selection	3082082
226888096	226888119		-	24336571	A375	resistance to PLX after 7 days	AAGACATGATCAACCAGCCATGG	PSEN2	ENSG00000143801	-0.05557406986989466	[20,17]	[18,17]	-1	hSpCas9	positive selection	3138296
226889004	226889027		-	24336571	A375	resistance to PLX after 7 days	ATGACCCACGCGGACCACTCTGG	PSEN2	ENSG00000143801	-0.07703715870023298	[39,39]	[34,39]	-2	hSpCas9	positive selection	3138297
226888958	226888981		+	24336571	A375	resistance to PLX after 7 days	CATCATGATCAGTGCGCTCATGG	PSEN2	ENSG00000143801	0.0103184818863844	[33,28]	[30,30]	0	hSpCas9	positive selection	3138298
226888136	226888159		+	24336571	A375	resistance to PLX after 7 days	CTCTTCACCTATATCTACCTTGG	PSEN2	ENSG00000143801	0.08440807543799744	[26,27]	[28,27]	3	hSpCas9	positive selection	3138299
226888990	226889013		+	24336571	A375	resistance to PLX after 7 days	TCATCAAGTACCTCCCAGAGTGG	PSEN2	ENSG00000143801	-0.20113327680168958	[14,16]	[15,11]	-6	hSpCas9	positive selection	3138300
226888083	226888106		+	24336571	A375	resistance to PLX after 7 days	TTGTCTAGTTCATCCATGGCTGG	PSEN2	ENSG00000143801	0.020036380184207614	[30,21]	[26,25]	0	hSpCas9	positive selection	3138301
226888096	226888119		-	24336571	A375	resistance to PLX after 14 days	AAGACATGATCAACCAGCCATGG	PSEN2	ENSG00000143801	-0.28574191599035736	[20,21]	[5,9]	-3	hSpCas9	positive selection	3196089
226889004	226889027		-	24336571	A375	resistance to PLX after 14 days	ATGACCCACGCGGACCACTCTGG	PSEN2	ENSG00000143801	-0.4018902212261357	[48,28]	[10,15]	-5	hSpCas9	positive selection	3196090
226888958	226888981		+	24336571	A375	resistance to PLX after 14 days	CATCATGATCAGTGCGCTCATGG	PSEN2	ENSG00000143801	-0.17965487485237586	[27,26]	[9,11]	-2	hSpCas9	positive selection	3196091
226888136	226888159		+	24336571	A375	resistance to PLX after 14 days	CTCTTCACCTATATCTACCTTGG	PSEN2	ENSG00000143801	-0.5410741619695824	[26,21]	[7,6]	-6	hSpCas9	positive selection	3196092
226888990	226889013		+	24336571	A375	resistance to PLX after 14 days	TCATCAAGTACCTCCCAGAGTGG	PSEN2	ENSG00000143801	-0.5492362254268566	[15,17]	[4,4]	-6	hSpCas9	positive selection	3196093
226888083	226888106		+	24336571	A375	resistance to PLX after 14 days	TTGTCTAGTTCATCCATGGCTGG	PSEN2	ENSG00000143801	-0.08312116497604882	[35,25]	[12,13]	-1	hSpCas9	positive selection	3196094
226888096	226888119		-	24336571	A375	viability after 7 days	AAGACATGATCAACCAGCCATGG	PSEN2	ENSG00000143801	0.034618667116672164	[19]	[20,17]	0	hSpCas9	negative selection	3253882
226889004	226889027		-	24336571	A375	viability after 7 days	ATGACCCACGCGGACCACTCTGG	PSEN2	ENSG00000143801	0.5008856940171973	[28]	[39,39]	7	hSpCas9	negative selection	3253883
226888958	226888981		+	24336571	A375	viability after 7 days	CATCATGATCAGTGCGCTCATGG	PSEN2	ENSG00000143801	0.1632789849631313	[28]	[33,28]	2	hSpCas9	negative selection	3253884
226888136	226888159		+	24336571	A375	viability after 7 days	CTCTTCACCTATATCTACCTTGG	PSEN2	ENSG00000143801	-0.5525261249589537	[41]	[26,27]	-7	hSpCas9	negative selection	3253885
226888990	226889013		+	24336571	A375	viability after 7 days	TCATCAAGTACCTCCCAGAGTGG	PSEN2	ENSG00000143801	0.13983127837137005	[14]	[14,16]	2	hSpCas9	negative selection	3253886
226888083	226888106		+	24336571	A375	viability after 7 days	TTGTCTAGTTCATCCATGGCTGG	PSEN2	ENSG00000143801	0.20278281587141422	[23]	[30,21]	3	hSpCas9	negative selection	3253887
226888096	226888119		-	24336571	A375	viability after 14 days	AAGACATGATCAACCAGCCATGG	PSEN2	ENSG00000143801	0.17140728561279106	[19]	[20,21]	2	hSpCas9	negative selection	3311675
226889004	226889027		-	24336571	A375	viability after 14 days	ATGACCCACGCGGACCACTCTGG	PSEN2	ENSG00000143801	0.49639660424319265	[28]	[48,28]	6	hSpCas9	negative selection	3311676
226888958	226888981		+	24336571	A375	viability after 14 days	CATCATGATCAGTGCGCTCATGG	PSEN2	ENSG00000143801	-0.014833061189835517	[28]	[27,26]	0	hSpCas9	negative selection	3311677
226888136	226888159		+	24336571	A375	viability after 14 days	CTCTTCACCTATATCTACCTTGG	PSEN2	ENSG00000143801	-0.6835802209545297	[41]	[26,21]	-7	hSpCas9	negative selection	3311678
226888990	226889013		+	24336571	A375	viability after 14 days	TCATCAAGTACCTCCCAGAGTGG	PSEN2	ENSG00000143801	0.26245946480408766	[14]	[15,17]	3	hSpCas9	negative selection	3311679
226888083	226888106		+	24336571	A375	viability after 14 days	TTGTCTAGTTCATCCATGGCTGG	PSEN2	ENSG00000143801	0.4445598712817016	[23]	[35,25]	5	hSpCas9	negative selection	3311680
226889004	226889027	1	-	27383988	293T	resistance to West Nile virus (flavivirus)	ATGACCCACGCGGACCACTCTGG	PSEN2	ENSG00000143801	0.8143827155971068	[86,86]	[0,0]	4	hSpCas9	positive selection	3387897
226894023	226894046	1	-	27383988	293T	resistance to West Nile virus (flavivirus)	TGTAGAAGATGAAGTCCCCGAGG	PSEN2	ENSG00000143801	0.057653866609470694	[146,146]	[0,0]	0	hSpCas9	positive selection	3387898
226894000	226894023	1	+	27383988	293T	resistance to West Nile virus (flavivirus)	CACACAGGGGGCGTGAAGCTTGG	PSEN2	ENSG00000143801	0.47596649792117546	[109,109]	[0,0]	2	hSpCas9	positive selection	3387899
226885658	226885681	1	+	26780180	HT29	viability (Avana library 4 designs)	CTACAAGTACCGCTGCTACAAGG	PSEN2	ENSG00000143801	-0.151081203822979	[]	[]	-2	hSpCas9	negative selection	3452449
226888877	226888900	1	+	26780180	HT29	viability (Avana library 4 designs)	GCTGACTGTCTGGAACTTCGGGG	PSEN2	ENSG00000143801	-0.399235433596112	[]	[]	-6	hSpCas9	negative selection	3452450
226883754	226883777	1	+	26780180	HT29	viability (Avana library 4 designs)	TCTGTAGTGGGGTTCCCGGGCGG	PSEN2	ENSG00000143801	0.825237318797816	[]	[]	3	hSpCas9	negative selection	3452451
226883743	226883766	1	+	26780180	HT29	viability (Avana library 4 designs)	TGACCGCTATGTCTGTAGTGGGG	PSEN2	ENSG00000143801	0.069687866314955	[]	[]	0	hSpCas9	negative selection	3452452
226883754	226883777	1	+	26780180	A375	viability (Avana lentiCRISPRv2)	TCTGTAGTGGGGTTCCCGGGCGG	PSEN2	ENSG00000143801	4.05219938445044	[]	[]	6	hSpCas9	negative selection	3548830
226885658	226885681	1	+	26780180	A375	viability (Avana lentiCRISPRv2)	CTACAAGTACCGCTGCTACAAGG	PSEN2	ENSG00000143801	2.25721915996648	[]	[]	3	hSpCas9	negative selection	3548831
226888877	226888900	1	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCTGACTGTCTGGAACTTCGGGG	PSEN2	ENSG00000143801	0.601434971587103	[]	[]	0	hSpCas9	negative selection	3548832
226883743	226883766	1	+	26780180	A375	viability (Avana lentiCRISPRv2)	TGACCGCTATGTCTGTAGTGGGG	PSEN2	ENSG00000143801	3.51605254596461	[]	[]	5	hSpCas9	negative selection	3548833
226885606	226885629	1	-	26780180	A375	viability (Avana lentiCRISPRv2)	GATGACGCTGATCATGATGAGGG	PSEN2	ENSG00000143801	1.97246472010017	[]	[]	3	hSpCas9	negative selection	3548834
226883704	226883727	1	+	26780180	A375	viability (Avana lentiCRISPRv2)	GAGAAGCCAGGAGAACGAGGAGG	PSEN2	ENSG00000143801	-6.18253701050725	[]	[]	-6	hSpCas9	negative selection	3548835
226883754	226883777	1	+	26780180	A375	viability (Avana lentiGuide)	TCTGTAGTGGGGTTCCCGGGCGG	PSEN2	ENSG00000143801	4.06138532853961	[]	[]	4	hSpCas9	negative selection	3657489
226885658	226885681	1	+	26780180	A375	viability (Avana lentiGuide)	CTACAAGTACCGCTGCTACAAGG	PSEN2	ENSG00000143801	-6.07191129959329	[]	[]	-8	hSpCas9	negative selection	3657490
226888877	226888900	1	+	26780180	A375	viability (Avana lentiGuide)	GCTGACTGTCTGGAACTTCGGGG	PSEN2	ENSG00000143801	6.90658087131739	[]	[]	5	hSpCas9	negative selection	3657491
226883743	226883766	1	+	26780180	A375	viability (Avana lentiGuide)	TGACCGCTATGTCTGTAGTGGGG	PSEN2	ENSG00000143801	0.467104426523905	[]	[]	0	hSpCas9	negative selection	3657492
226885606	226885629	1	-	26780180	A375	viability (Avana lentiGuide)	GATGACGCTGATCATGATGAGGG	PSEN2	ENSG00000143801	3.5536262091423	[]	[]	3	hSpCas9	negative selection	3657493
226883704	226883727	1	+	26780180	A375	viability (Avana lentiGuide)	GAGAAGCCAGGAGAACGAGGAGG	PSEN2	ENSG00000143801	15.8361209729908	[]	[]	8	hSpCas9	negative selection	3657494
226883754	226883777	1	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TCTGTAGTGGGGTTCCCGGGCGG	PSEN2	ENSG00000143801	0.3572397434278654	[4]	[5,5]	9	hSpCas9	positive selection	3766096
226885658	226885681	1	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CTACAAGTACCGCTGCTACAAGG	PSEN2	ENSG00000143801	-0.008802440106801285	[6]	[6,5]	0	hSpCas9	positive selection	3766097
226888877	226888900	1	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCTGACTGTCTGGAACTTCGGGG	PSEN2	ENSG00000143801	0.05356511540559426	[4]	[4,4]	1	hSpCas9	positive selection	3766098
226883743	226883766	1	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TGACCGCTATGTCTGTAGTGGGG	PSEN2	ENSG00000143801	0.2051290846618723	[6]	[7,7]	6	hSpCas9	positive selection	3766099
226885606	226885629	1	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GATGACGCTGATCATGATGAGGG	PSEN2	ENSG00000143801	0.12127101006209529	[6]	[7,7]	3	hSpCas9	positive selection	3766100
226883704	226883727	1	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GAGAAGCCAGGAGAACGAGGAGG	PSEN2	ENSG00000143801	-0.27827915517717083	[5]	[4,3]	-4	hSpCas9	positive selection	3766101
226883754	226883777	1	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TCTGTAGTGGGGTTCCCGGGCGG	PSEN2	ENSG00000143801	0.04415557194153726	[5]	[4,4]	0	hSpCas9	positive selection	3874703
226885658	226885681	1	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CTACAAGTACCGCTGCTACAAGG	PSEN2	ENSG00000143801	0.22276872009621307	[6]	[8,5]	6	hSpCas9	positive selection	3874704
226888877	226888900	1	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCTGACTGTCTGGAACTTCGGGG	PSEN2	ENSG00000143801	0.11754697995317652	[5]	[5,3]	2	hSpCas9	positive selection	3874705
226883743	226883766	1	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TGACCGCTATGTCTGTAGTGGGG	PSEN2	ENSG00000143801	0.11098572416628899	[6]	[6,5]	2	hSpCas9	positive selection	3874706
226885606	226885629	1	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GATGACGCTGATCATGATGAGGG	PSEN2	ENSG00000143801	0.12414742547177465	[7]	[6,6]	3	hSpCas9	positive selection	3874707
226883704	226883727	1	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GAGAAGCCAGGAGAACGAGGAGG	PSEN2	ENSG00000143801	-0.8522453927881034	[6]	[3,0]	-8	hSpCas9	positive selection	3874708
226883843	226883866	1	-	26780180	A375	viability	ACGATCATGCACAGAGTGACAGG	PSEN2	ENSG00000143801	0.88462769834596	[]	[]	4	hSpCas9	negative selection	3985140
226889004	226889027	1	-	26780180	A375	viability	ATGACCCACGCGGACCACTCTGG	PSEN2	ENSG00000143801	1.45232737239061	[]	[]	8	hSpCas9	negative selection	3985141
226894000	226894023	1	+	26780180	A375	viability	CACACAGGGGGCGTGAAGCTTGG	PSEN2	ENSG00000143801	1.023783170507	[]	[]	5	hSpCas9	negative selection	3985142
226888958	226888981	1	+	26780180	A375	viability	CATCATGATCAGTGCGCTCATGG	PSEN2	ENSG00000143801	1.62694883925943	[]	[]	8	hSpCas9	negative selection	3985143
226883803	226883826	1	-	26780180	A375	viability	CGTGCTTCGCTCCGTATTTGAGG	PSEN2	ENSG00000143801	0.224809842660875	[]	[]	0	hSpCas9	negative selection	3985144
226894023	226894046	1	-	26780180	A375	viability	TGTAGAAGATGAAGTCCCCGAGG	PSEN2	ENSG00000143801	1.11235416257897	[]	[]	5	hSpCas9	negative selection	3985145
226883843	226883866	1	-	26780180	HT29	viability (GeCKOv2 library)	ACGATCATGCACAGAGTGACAGG	PSEN2	ENSG00000143801	2.08644991587415	[]	[]	9	hSpCas9	negative selection	4093106
226889004	226889027	1	-	26780180	HT29	viability (GeCKOv2 library)	ATGACCCACGCGGACCACTCTGG	PSEN2	ENSG00000143801	0.810020950728025	[]	[]	3	hSpCas9	negative selection	4093107
226894000	226894023	1	+	26780180	HT29	viability (GeCKOv2 library)	CACACAGGGGGCGTGAAGCTTGG	PSEN2	ENSG00000143801	1.1724348870852	[]	[]	5	hSpCas9	negative selection	4093108
226888958	226888981	1	+	26780180	HT29	viability (GeCKOv2 library)	CATCATGATCAGTGCGCTCATGG	PSEN2	ENSG00000143801	0.944416894424158	[]	[]	4	hSpCas9	negative selection	4093109
226883803	226883826	1	-	26780180	HT29	viability (GeCKOv2 library)	CGTGCTTCGCTCCGTATTTGAGG	PSEN2	ENSG00000143801	0.142151872254772	[]	[]	0	hSpCas9	negative selection	4093110
226894023	226894046	1	-	26780180	HT29	viability (GeCKOv2 library)	TGTAGAAGATGAAGTCCCCGAGG	PSEN2	ENSG00000143801	1.11555345464779	[]	[]	5	hSpCas9	negative selection	4093111
226888096	226888119	1	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	AAGACATGATCAACCAGCCATGG	PSEN2	ENSG00000143801	0.04967109463499968	[3]	[2,2]	1	hSpCas9	positive selection	4163512
226889004	226889027	1	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	ATGACCCACGCGGACCACTCTGG	PSEN2	ENSG00000143801	0.24593886687055344	[5]	[4,3]	6	hSpCas9	positive selection	4163513
226888958	226888981	1	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CATCATGATCAGTGCGCTCATGG	PSEN2	ENSG00000143801	0.14495852367213397	[4]	[3,3]	4	hSpCas9	positive selection	4163514
226888136	226888159	1	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CTCTTCACCTATATCTACCTTGG	PSEN2	ENSG00000143801	-0.0697257534535072	[4]	[2,2]	-2	hSpCas9	positive selection	4163515
226888990	226889013	1	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TCATCAAGTACCTCCCAGAGTGG	PSEN2	ENSG00000143801	0.08067064324211691	[4]	[3,2]	2	hSpCas9	positive selection	4163516
226888083	226888106	1	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TTGTCTAGTTCATCCATGGCTGG	PSEN2	ENSG00000143801	0.17503574650242956	[4]	[2,3]	4	hSpCas9	positive selection	4163517
226888096	226888119	1	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	AAGACATGATCAACCAGCCATGG	PSEN2	ENSG00000143801	0.5398610544275186	[4]	[0,0,4,3]	4	hSpCas9	positive selection	4227534
226889004	226889027	1	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	ATGACCCACGCGGACCACTCTGG	PSEN2	ENSG00000143801	0.9265895773876794	[4]	[3,4,2,3]	6	hSpCas9	positive selection	4227535
226888958	226888981	1	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CATCATGATCAGTGCGCTCATGG	PSEN2	ENSG00000143801	1.0667266360711734	[4]	[5,5,3,3]	7	hSpCas9	positive selection	4227536
226888136	226888159	1	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CTCTTCACCTATATCTACCTTGG	PSEN2	ENSG00000143801	0.5912280971943201	[5]	[3,1,4,3]	4	hSpCas9	positive selection	4227537
226888990	226889013	1	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TCATCAAGTACCTCCCAGAGTGG	PSEN2	ENSG00000143801	1.1682219852976474	[3]	[0,1,4,4]	8	hSpCas9	positive selection	4227538
226888083	226888106	1	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TTGTCTAGTTCATCCATGGCTGG	PSEN2	ENSG00000143801	0.7066364859886949	[4]	[0,3,2,4]	4	hSpCas9	positive selection	4227539
226883803	226883826	1	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CGTGCTTCGCTCCGTATTTGAGG	PSEN2	ENSG00000143801	0.6991590197710595	[2]	[3,3]	9	hSpCas9	positive selection	4292660
226883843	226883866	1	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ACGATCATGCACAGAGTGACAGG	PSEN2	ENSG00000143801	-0.5913108239493763	[3]	[2,0]	-8	hSpCas9	positive selection	4292661
226888958	226888981	1	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CATCATGATCAGTGCGCTCATGG	PSEN2	ENSG00000143801	0.18305743309728087	[3]	[3,1]	3	hSpCas9	positive selection	4292662
226889004	226889027	1	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ATGACCCACGCGGACCACTCTGG	PSEN2	ENSG00000143801	-0.6165244142733178	[2]	[1,0]	-8	hSpCas9	positive selection	4356919
226894023	226894046	1	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TGTAGAAGATGAAGTCCCCGAGG	PSEN2	ENSG00000143801	-0.13682543808017616	[2]	[2,1]	-3	hSpCas9	positive selection	4356920
226894000	226894023	1	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CACACAGGGGGCGTGAAGCTTGG	PSEN2	ENSG00000143801	0.18569934171359015	[2]	[2,1]	4	hSpCas9	positive selection	4356921
226883746	226883768	1	-	27760321	OCIAML3	viability	AACCCCACTACAGACATAGCGG	PSEN2	ENSG00000143801	0.8062122344906797	[371,286]	[320,611]	8	hSpCas9	negative selection	4431276
226883846	226883868	1	+	27760321	OCIAML3	viability	GTCACTCTGTGCATGATCGTGG	PSEN2	ENSG00000143801	0.5514113412877284	[843,703]	[869,900]	6	hSpCas9	negative selection	4431277
226888080	226888102	1	+	27760321	OCIAML3	viability	CTGTTGTCTAGTTCATCCATGG	PSEN2	ENSG00000143801	0.1447916905063303	[343,337]	[180,444]	1	hSpCas9	negative selection	4431278
226888908	226888930	1	+	27760321	OCIAML3	viability	ATGGTGTGCATCCACTGGAAGG	PSEN2	ENSG00000143801	0.460557965964273	[493,429]	[449,555]	5	hSpCas9	negative selection	4431279
226889010	226889032	1	+	27760321	OCIAML3	viability	TGGTCCGCGTGGGTCATCCTGG	PSEN2	ENSG00000143801	0.5034904804365464	[654,643]	[678,777]	6	hSpCas9	negative selection	4431280
226883746	226883768	1	-	27760321	OCIAML2	viability	AACCCCACTACAGACATAGCGG	PSEN2	ENSG00000143801	0.06465422743176297	[371,286]	[252,307]	0	hSpCas9	negative selection	4514739
226883846	226883868	1	+	27760321	OCIAML2	viability	GTCACTCTGTGCATGATCGTGG	PSEN2	ENSG00000143801	-0.33302916848163	[843,703]	[409,606]	-4	hSpCas9	negative selection	4514740
226888080	226888102	1	+	27760321	OCIAML2	viability	CTGTTGTCTAGTTCATCCATGG	PSEN2	ENSG00000143801	-0.1533149622199113	[343,337]	[211,296]	-2	hSpCas9	negative selection	4514741
226888908	226888930	1	+	27760321	OCIAML2	viability	ATGGTGTGCATCCACTGGAAGG	PSEN2	ENSG00000143801	0.26818625122313966	[493,429]	[467,423]	3	hSpCas9	negative selection	4514742
226889010	226889032	1	+	27760321	OCIAML2	viability	TGGTCCGCGTGGGTCATCCTGG	PSEN2	ENSG00000143801	0.36085390815156326	[654,643]	[584,796]	5	hSpCas9	negative selection	4514743
226883746	226883768	1	-	27760321	MV411	viability	AACCCCACTACAGACATAGCGG	PSEN2	ENSG00000143801	1.2281105949026303	[371,286]	[563,417]	8	hSpCas9	negative selection	4598202
226883846	226883868	1	+	27760321	MV411	viability	GTCACTCTGTGCATGATCGTGG	PSEN2	ENSG00000143801	0.7706638734538518	[843,703]	[364,1622]	5	hSpCas9	negative selection	4598203
226888080	226888102	1	+	27760321	MV411	viability	CTGTTGTCTAGTTCATCCATGG	PSEN2	ENSG00000143801	0.42113644805621797	[343,337]	[395,160]	3	hSpCas9	negative selection	4598204
226888908	226888930	1	+	27760321	MV411	viability	ATGGTGTGCATCCACTGGAAGG	PSEN2	ENSG00000143801	0.8446025814393971	[493,429]	[749,239]	6	hSpCas9	negative selection	4598205
226889010	226889032	1	+	27760321	MV411	viability	TGGTCCGCGTGGGTCATCCTGG	PSEN2	ENSG00000143801	0.6077630829164723	[654,643]	[703,580]	4	hSpCas9	negative selection	4598206
226883746	226883768	1	-	27760321	HL60	viability	AACCCCACTACAGACATAGCGG	PSEN2	ENSG00000143801	0.23417700903408878	[371,286]	[273,356]	3	hSpCas9	negative selection	4681665
226883846	226883868	1	+	27760321	HL60	viability	GTCACTCTGTGCATGATCGTGG	PSEN2	ENSG00000143801	-0.07646553033128123	[843,703]	[634,556]	-1	hSpCas9	negative selection	4681666
226888080	226888102	1	+	27760321	HL60	viability	CTGTTGTCTAGTTCATCCATGG	PSEN2	ENSG00000143801	-0.027126222960600854	[343,337]	[209,341]	0	hSpCas9	negative selection	4681667
226888908	226888930	1	+	27760321	HL60	viability	ATGGTGTGCATCCACTGGAAGG	PSEN2	ENSG00000143801	-0.7757980100160355	[493,429]	[232,205]	-7	hSpCas9	negative selection	4681668
226889010	226889032	1	+	27760321	HL60	viability	TGGTCCGCGTGGGTCATCCTGG	PSEN2	ENSG00000143801	0.4177405340487974	[654,643]	[679,742]	5	hSpCas9	negative selection	4681669
226883746	226883768	1	-	27760321	HT1080	viability	AACCCCACTACAGACATAGCGG	PSEN2	ENSG00000143801	-0.03549659275631373	[286,223]	[10,195]	0	hSpCas9	negative selection	4765128
226883846	226883868	1	+	27760321	HT1080	viability	GTCACTCTGTGCATGATCGTGG	PSEN2	ENSG00000143801	0.9594420341075403	[703,549]	[553,410]	5	hSpCas9	negative selection	4765129
226888080	226888102	1	+	27760321	HT1080	viability	CTGTTGTCTAGTTCATCCATGG	PSEN2	ENSG00000143801	0.6053991267139346	[337,263]	[275,79]	3	hSpCas9	negative selection	4765130
226888908	226888930	1	+	27760321	HT1080	viability	ATGGTGTGCATCCACTGGAAGG	PSEN2	ENSG00000143801	0.19869733900230183	[429,335]	[145,206]	1	hSpCas9	negative selection	4765131
226889010	226889032	1	+	27760321	HT1080	viability	TGGTCCGCGTGGGTCATCCTGG	PSEN2	ENSG00000143801	0.689995523352499	[643,502]	[64,700]	3	hSpCas9	negative selection	4765132
226883746	226883768	1	-	27760321	HT29	viability after 7 days	AACCCCACTACAGACATAGCGG	PSEN2	ENSG00000143801	0.30371517724892094	[286,223]	[630,338,281]	4	hSpCas9	negative selection	4848591
226883846	226883868	1	+	27760321	HT29	viability after 7 days	GTCACTCTGTGCATGATCGTGG	PSEN2	ENSG00000143801	-0.4290546044224025	[703,549]	[555,652,580]	-6	hSpCas9	negative selection	4848592
226888080	226888102	1	+	27760321	HT29	viability after 7 days	CTGTTGTCTAGTTCATCCATGG	PSEN2	ENSG00000143801	0.12788112506848504	[337,263]	[349,272,627]	2	hSpCas9	negative selection	4848593
226888908	226888930	1	+	27760321	HT29	viability after 7 days	ATGGTGTGCATCCACTGGAAGG	PSEN2	ENSG00000143801	-0.15384294112446747	[429,335]	[586,543,223]	-2	hSpCas9	negative selection	4848594
226889010	226889032	1	+	27760321	HT29	viability after 7 days	TGGTCCGCGTGGGTCATCCTGG	PSEN2	ENSG00000143801	-0.17875959699412314	[643,502]	[565,588,781]	-3	hSpCas9	negative selection	4848595
226883746	226883768	1	-	27760321	HT29	viability after 25 days	AACCCCACTACAGACATAGCGG	PSEN2	ENSG00000143801	0.5808831394567914	[286,223]	[425,423,462]	6	hSpCas9	negative selection	4932054
226883846	226883868	1	+	27760321	HT29	viability after 25 days	GTCACTCTGTGCATGATCGTGG	PSEN2	ENSG00000143801	0.025615703821914804	[703,549]	[786,559,848]	0	hSpCas9	negative selection	4932055
226888080	226888102	1	+	27760321	HT29	viability after 25 days	CTGTTGTCTAGTTCATCCATGG	PSEN2	ENSG00000143801	-0.2196942688900893	[337,263]	[204,334,357]	-2	hSpCas9	negative selection	4932056
226888908	226888930	1	+	27760321	HT29	viability after 25 days	ATGGTGTGCATCCACTGGAAGG	PSEN2	ENSG00000143801	0.5452861858279902	[429,335]	[588,703,623]	6	hSpCas9	negative selection	4932057
226889010	226889032	1	+	27760321	HT29	viability after 25 days	TGGTCCGCGTGGGTCATCCTGG	PSEN2	ENSG00000143801	0.4112114272723979	[643,502]	[811,616,1224]	4	hSpCas9	negative selection	4932058
226883746	226883768	1	-	27760321	HT29	viability after 22 days	AACCCCACTACAGACATAGCGG	PSEN2	ENSG00000143801	0.8529742285826265	[286,223]	[339,598,667]	8	hSpCas9	negative selection	5015517
226883846	226883868	1	+	27760321	HT29	viability after 22 days	GTCACTCTGTGCATGATCGTGG	PSEN2	ENSG00000143801	0.08011530458346039	[703,549]	[797,728,770]	0	hSpCas9	negative selection	5015518
226888080	226888102	1	+	27760321	HT29	viability after 22 days	CTGTTGTCTAGTTCATCCATGG	PSEN2	ENSG00000143801	-0.43523706508266874	[337,263]	[336,271,159]	-4	hSpCas9	negative selection	5015519
226888908	226888930	1	+	27760321	HT29	viability after 22 days	ATGGTGTGCATCCACTGGAAGG	PSEN2	ENSG00000143801	0.5742686753173153	[429,335]	[736,553,684]	6	hSpCas9	negative selection	5015520
226889010	226889032	1	+	27760321	HT29	viability after 22 days	TGGTCCGCGTGGGTCATCCTGG	PSEN2	ENSG00000143801	0.1792188462304345	[643,502]	[854,572,821]	1	hSpCas9	negative selection	5015521
226883746	226883768	1	-	27760321	HT29	viability after 19 days	AACCCCACTACAGACATAGCGG	PSEN2	ENSG00000143801	0.42604212132300545	[286,223]	[619,313,271]	4	hSpCas9	negative selection	5098980
226883846	226883868	1	+	27760321	HT29	viability after 19 days	GTCACTCTGTGCATGATCGTGG	PSEN2	ENSG00000143801	0.24955659523123996	[703,549]	[951,588,1019]	2	hSpCas9	negative selection	5098981
226888080	226888102	1	+	27760321	HT29	viability after 19 days	CTGTTGTCTAGTTCATCCATGG	PSEN2	ENSG00000143801	-0.4450234392935069	[337,263]	[354,236,179]	-4	hSpCas9	negative selection	5098982
226888908	226888930	1	+	27760321	HT29	viability after 19 days	ATGGTGTGCATCCACTGGAAGG	PSEN2	ENSG00000143801	0.03784962332379299	[429,335]	[636,350,382]	0	hSpCas9	negative selection	5098983
226889010	226889032	1	+	27760321	HT29	viability after 19 days	TGGTCCGCGTGGGTCATCCTGG	PSEN2	ENSG00000143801	0.31009491141120415	[643,502]	[809,982,651]	3	hSpCas9	negative selection	5098984
226883746	226883768	1	-	27760321	HT29	viability after 16 days	AACCCCACTACAGACATAGCGG	PSEN2	ENSG00000143801	0.9007455313708977	[286,223]	[540,598,459]	9	hSpCas9	negative selection	5182443
226883846	226883868	1	+	27760321	HT29	viability after 16 days	GTCACTCTGTGCATGATCGTGG	PSEN2	ENSG00000143801	0.0199306818904339	[703,549]	[949,416,796]	0	hSpCas9	negative selection	5182444
226888080	226888102	1	+	27760321	HT29	viability after 16 days	CTGTTGTCTAGTTCATCCATGG	PSEN2	ENSG00000143801	0.5157029254592952	[337,263]	[601,280,577]	6	hSpCas9	negative selection	5182445
226888908	226888930	1	+	27760321	HT29	viability after 16 days	ATGGTGTGCATCCACTGGAAGG	PSEN2	ENSG00000143801	0.31837477897394206	[429,335]	[496,550,550]	3	hSpCas9	negative selection	5182446
226889010	226889032	1	+	27760321	HT29	viability after 16 days	TGGTCCGCGTGGGTCATCCTGG	PSEN2	ENSG00000143801	0.22949803602805008	[643,502]	[827,596,842]	2	hSpCas9	negative selection	5182447
226883746	226883768	1	-	27760321	HT29	viability after 13 days	AACCCCACTACAGACATAGCGG	PSEN2	ENSG00000143801	0.7090327910213418	[286,223]	[458,482,509]	8	hSpCas9	negative selection	5265906
226883846	226883868	1	+	27760321	HT29	viability after 13 days	GTCACTCTGTGCATGATCGTGG	PSEN2	ENSG00000143801	-0.0944580322556885	[703,549]	[653,760,631]	-1	hSpCas9	negative selection	5265907
226888080	226888102	1	+	27760321	HT29	viability after 13 days	CTGTTGTCTAGTTCATCCATGG	PSEN2	ENSG00000143801	0.26304534791578754	[337,263]	[372,495,389]	3	hSpCas9	negative selection	5265908
226888908	226888930	1	+	27760321	HT29	viability after 13 days	ATGGTGTGCATCCACTGGAAGG	PSEN2	ENSG00000143801	0.5385194639855171	[429,335]	[829,635,479]	7	hSpCas9	negative selection	5265909
226889010	226889032	1	+	27760321	HT29	viability after 13 days	TGGTCCGCGTGGGTCATCCTGG	PSEN2	ENSG00000143801	0.37062067070834526	[643,502]	[955,979,656]	5	hSpCas9	negative selection	5265910
226883746	226883768	1	-	27760321	HT29	viability after 10 days	AACCCCACTACAGACATAGCGG	PSEN2	ENSG00000143801	1.0077630644242177	[286,223]	[862,476,580]	9	hSpCas9	negative selection	5349369
226883846	226883868	1	+	27760321	HT29	viability after 10 days	GTCACTCTGTGCATGATCGTGG	PSEN2	ENSG00000143801	-0.0421081663224282	[703,549]	[645,951,689]	0	hSpCas9	negative selection	5349370
226888080	226888102	1	+	27760321	HT29	viability after 10 days	CTGTTGTCTAGTTCATCCATGG	PSEN2	ENSG00000143801	0.24710650518106234	[337,263]	[426,372,533]	3	hSpCas9	negative selection	5349371
226888908	226888930	1	+	27760321	HT29	viability after 10 days	ATGGTGTGCATCCACTGGAAGG	PSEN2	ENSG00000143801	0.31428853226279396	[429,335]	[618,707,462]	4	hSpCas9	negative selection	5349372
226889010	226889032	1	+	27760321	HT29	viability after 10 days	TGGTCCGCGTGGGTCATCCTGG	PSEN2	ENSG00000143801	-0.09082625963151902	[643,502]	[596,684,733]	-1	hSpCas9	negative selection	5349373
226883746	226883768	1	-	27760321	MOLM13	viability	AACCCCACTACAGACATAGCGG	PSEN2	ENSG00000143801	0.9546889426922331	[371,286]	[166,519]	6	hSpCas9	negative selection	5432832
226883846	226883868	1	+	27760321	MOLM13	viability	GTCACTCTGTGCATGATCGTGG	PSEN2	ENSG00000143801	0.2948478933756411	[843,703]	[499,561]	2	hSpCas9	negative selection	5432833
226888080	226888102	1	+	27760321	MOLM13	viability	CTGTTGTCTAGTTCATCCATGG	PSEN2	ENSG00000143801	0.4669078997090996	[343,337]	[493,72]	3	hSpCas9	negative selection	5432834
226888908	226888930	1	+	27760321	MOLM13	viability	ATGGTGTGCATCCACTGGAAGG	PSEN2	ENSG00000143801	1.1758067154930296	[493,429]	[782,420]	8	hSpCas9	negative selection	5432835
226889010	226889032	1	+	27760321	MOLM13	viability	TGGTCCGCGTGGGTCATCCTGG	PSEN2	ENSG00000143801	1.1614898139553684	[654,643]	[904,750]	7	hSpCas9	negative selection	5432836
226870616	226870639	1	+	27661255	K562	viability	GCGTAAACTCCGCTGGAGCGCGG	PSEN2	ENSG00000143801	0.17997148691444353	[205,276]	[218,215]	6	dCas9-KRAB	negative selection	5504767
226870990	226871013	1	+	27661255	K562	viability	GCGCGGCGCGAGCGGTTAAAGGG	PSEN2	ENSG00000143801	0.29009744646392766	[262,196]	[241,211]	8	dCas9-KRAB	negative selection	5504768
226870994	226871017	1	+	27661255	K562	viability	GGCGCGAGCGGTTAAAGGGCCGG	PSEN2	ENSG00000143801	-0.00425162753106223	[339,363]	[306,256]	0	dCas9-KRAB	negative selection	5504769
226871011	226871034	1	+	27661255	K562	viability	GGCCGGTGCATTTAAAGGAGCGG	PSEN2	ENSG00000143801	-0.08986217924051565	[449,298]	[321,249]	-3	dCas9-KRAB	negative selection	5504770
226883803	226883826	1	-	27260156	BXPC3	viability	CGTGCTTCGCTCCGTATTTGAGG	PSEN2	ENSG00000143801	0.3407275612690626	[309]	[385,400,410,448]	7	hSpCas9	negative selection	5565120
226883843	226883866	1	-	27260156	BXPC3	viability	ACGATCATGCACAGAGTGACAGG	PSEN2	ENSG00000143801	-0.04371589955558685	[496]	[471,484,487,581]	-1	hSpCas9	negative selection	5565121
226888958	226888981	1	+	27260156	BXPC3	viability	CATCATGATCAGTGCGCTCATGG	PSEN2	ENSG00000143801	0.16647696765348302	[559]	[605,589,730,714]	3	hSpCas9	negative selection	5565122
226889004	226889027	1	-	27260156	BXPC3	viability	ATGACCCACGCGGACCACTCTGG	PSEN2	ENSG00000143801	0.17413721264617854	[296]	[426,308,282,375]	4	hSpCas9	negative selection	5629379
226894023	226894046	1	-	27260156	BXPC3	viability	TGTAGAAGATGAAGTCCCCGAGG	PSEN2	ENSG00000143801	0.04572284967591683	[354]	[379,372,352,429]	1	hSpCas9	negative selection	5629380
226894000	226894023	1	+	27260156	BXPC3	viability	CACACAGGGGGCGTGAAGCTTGG	PSEN2	ENSG00000143801	-0.01505322558146216	[227]	[238,203,240,262]	0	hSpCas9	negative selection	5629381
226883803	226883826	1	-	27260156	A673	viability	CGTGCTTCGCTCCGTATTTGAGG	PSEN2	ENSG00000143801	0.6600670979916671	[309]	[645,573,490,651]	9	hSpCas9	negative selection	5686371
226883843	226883866	1	-	27260156	A673	viability	ACGATCATGCACAGAGTGACAGG	PSEN2	ENSG00000143801	-0.11039844475079887	[496]	[593,417,498,716]	-3	hSpCas9	negative selection	5686372
226888958	226888981	1	+	27260156	A673	viability	CATCATGATCAGTGCGCTCATGG	PSEN2	ENSG00000143801	0.24783704704173237	[559]	[808,698,846,842]	6	hSpCas9	negative selection	5686373
226889004	226889027	1	-	27260156	A673	viability	ATGACCCACGCGGACCACTCTGG	PSEN2	ENSG00000143801	-0.20007249283256479	[296]	[367,286,306,284]	-5	hSpCas9	negative selection	5750630
226894023	226894046	1	-	27260156	A673	viability	TGTAGAAGATGAAGTCCCCGAGG	PSEN2	ENSG00000143801	-0.29792127781035843	[354]	[368,337,307,375]	-6	hSpCas9	negative selection	5750631
226894000	226894023	1	+	27260156	A673	viability	CACACAGGGGGCGTGAAGCTTGG	PSEN2	ENSG00000143801	0.22918774180119394	[227]	[311,321,353,291]	5	hSpCas9	negative selection	5750632
226883803	226883826	1	-	27260156	A375	viability	CGTGCTTCGCTCCGTATTTGAGG	PSEN2	ENSG00000143801	0.8743899809279039	[309]	[662,739,650,614]	9	hSpCas9	negative selection	5807622
226883843	226883866	1	-	27260156	A375	viability	ACGATCATGCACAGAGTGACAGG	PSEN2	ENSG00000143801	-0.19759759572873875	[496]	[595,448,542,435]	-3	hSpCas9	negative selection	5807623
226888958	226888981	1	+	27260156	A375	viability	CATCATGATCAGTGCGCTCATGG	PSEN2	ENSG00000143801	-0.09154359041621751	[559]	[576,671,663,554]	-1	hSpCas9	negative selection	5807624
226889004	226889027	1	-	27260156	A375	viability	ATGACCCACGCGGACCACTCTGG	PSEN2	ENSG00000143801	-0.3976383172194511	[296]	[149,250,276,359]	-5	hSpCas9	negative selection	5871881
226894023	226894046	1	-	27260156	A375	viability	TGTAGAAGATGAAGTCCCCGAGG	PSEN2	ENSG00000143801	-0.29864917726679113	[354]	[388,379,427,175]	-4	hSpCas9	negative selection	5871882
226894000	226894023	1	+	27260156	A375	viability	CACACAGGGGGCGTGAAGCTTGG	PSEN2	ENSG00000143801	-0.15969069343667797	[227]	[106,295,320,235]	-2	hSpCas9	negative selection	5871883
226883803	226883826	1	-	27260156	COLO741	viability	CGTGCTTCGCTCCGTATTTGAGG	PSEN2	ENSG00000143801	0.671587223296945	[309]	[857,475,579]	9	hSpCas9	negative selection	5928873
226883843	226883866	1	-	27260156	COLO741	viability	ACGATCATGCACAGAGTGACAGG	PSEN2	ENSG00000143801	-0.18456695945849305	[496]	[592,527,556]	-4	hSpCas9	negative selection	5928874
226888958	226888981	1	+	27260156	COLO741	viability	CATCATGATCAGTGCGCTCATGG	PSEN2	ENSG00000143801	0.20687344978314876	[559]	[908,795,780]	4	hSpCas9	negative selection	5928875
226889004	226889027	1	-	27260156	COLO741	viability	ATGACCCACGCGGACCACTCTGG	PSEN2	ENSG00000143801	-0.03356658071733509	[296]	[476,380,269]	0	hSpCas9	negative selection	5993132
226894023	226894046	1	-	27260156	COLO741	viability	TGTAGAAGATGAAGTCCCCGAGG	PSEN2	ENSG00000143801	-0.04886952091114699	[354]	[435,505,376]	-1	hSpCas9	negative selection	5993133
226894000	226894023	1	+	27260156	COLO741	viability	CACACAGGGGGCGTGAAGCTTGG	PSEN2	ENSG00000143801	0.04905968600612376	[227]	[361,223,320]	1	hSpCas9	negative selection	5993134
226883803	226883826	1	-	27260156	CAL120	viability	CGTGCTTCGCTCCGTATTTGAGG	PSEN2	ENSG00000143801	0.8384251102322055	[309]	[1038,415,666]	9	hSpCas9	negative selection	6050124
226883843	226883866	1	-	27260156	CAL120	viability	ACGATCATGCACAGAGTGACAGG	PSEN2	ENSG00000143801	0.3595103035566245	[496]	[761,910,703]	5	hSpCas9	negative selection	6050125
226888958	226888981	1	+	27260156	CAL120	viability	CATCATGATCAGTGCGCTCATGG	PSEN2	ENSG00000143801	0.09702659813157938	[559]	[887,558,808]	1	hSpCas9	negative selection	6050126
226889004	226889027	1	-	27260156	CAL120	viability	ATGACCCACGCGGACCACTCTGG	PSEN2	ENSG00000143801	0.17675194107494419	[296]	[379,426,439]	2	hSpCas9	negative selection	6114383
226894023	226894046	1	-	27260156	CAL120	viability	TGTAGAAGATGAAGTCCCCGAGG	PSEN2	ENSG00000143801	-0.28526954315759306	[354]	[366,300,418]	-4	hSpCas9	negative selection	6114384
226894000	226894023	1	+	27260156	CAL120	viability	CACACAGGGGGCGTGAAGCTTGG	PSEN2	ENSG00000143801	-0.13814978126356192	[227]	[335,241,207]	-2	hSpCas9	negative selection	6114385
226883803	226883826	1	-	27260156	CADOES1	viability	CGTGCTTCGCTCCGTATTTGAGG	PSEN2	ENSG00000143801	0.7850242116811117	[309]	[452,539,533,458]	9	hSpCas9	negative selection	6171375
226883843	226883866	1	-	27260156	CADOES1	viability	ACGATCATGCACAGAGTGACAGG	PSEN2	ENSG00000143801	-0.14547201441606677	[496]	[419,523,407,315]	-3	hSpCas9	negative selection	6171376
226888958	226888981	1	+	27260156	CADOES1	viability	CATCATGATCAGTGCGCTCATGG	PSEN2	ENSG00000143801	0.033509208710438554	[559]	[578,470,447,637]	0	hSpCas9	negative selection	6171377
226889004	226889027	1	-	27260156	CADOES1	viability	ATGACCCACGCGGACCACTCTGG	PSEN2	ENSG00000143801	-0.18969925485643357	[296]	[200,253,268,244]	-3	hSpCas9	negative selection	6235634
226894023	226894046	1	-	27260156	CADOES1	viability	TGTAGAAGATGAAGTCCCCGAGG	PSEN2	ENSG00000143801	-0.3237892324168243	[354]	[193,315,318,224]	-5	hSpCas9	negative selection	6235635
226894000	226894023	1	+	27260156	CADOES1	viability	CACACAGGGGGCGTGAAGCTTGG	PSEN2	ENSG00000143801	-0.4399200267853558	[227]	[205,121,142,153]	-6	hSpCas9	negative selection	6235636
226883803	226883826	1	-	27260156	EWS502	viability	CGTGCTTCGCTCCGTATTTGAGG	PSEN2	ENSG00000143801	0.49383190028821217	[309]	[325,585,428,521]	8	hSpCas9	negative selection	6292626
226883843	226883866	1	-	27260156	EWS502	viability	ACGATCATGCACAGAGTGACAGG	PSEN2	ENSG00000143801	-0.0537234481434645	[496]	[448,441,531,621]	-1	hSpCas9	negative selection	6292627
226888958	226888981	1	+	27260156	EWS502	viability	CATCATGATCAGTGCGCTCATGG	PSEN2	ENSG00000143801	0.1630446391790658	[559]	[580,586,796,706]	3	hSpCas9	negative selection	6292628
226889004	226889027	1	-	27260156	EWS502	viability	ATGACCCACGCGGACCACTCTGG	PSEN2	ENSG00000143801	-0.031222816009354726	[296]	[280,309,265,380]	0	hSpCas9	negative selection	6356885
226894023	226894046	1	-	27260156	EWS502	viability	TGTAGAAGATGAAGTCCCCGAGG	PSEN2	ENSG00000143801	-0.2099446665602031	[354]	[380,292,344,270]	-4	hSpCas9	negative selection	6356886
226894000	226894023	1	+	27260156	EWS502	viability	CACACAGGGGGCGTGAAGCTTGG	PSEN2	ENSG00000143801	-0.19743056551880445	[227]	[347,127,145,204]	-4	hSpCas9	negative selection	6356887
226883803	226883826	1	-	27260156	EW8	viability	CGTGCTTCGCTCCGTATTTGAGG	PSEN2	ENSG00000143801	0.5088048047008769	[309]	[296,369,441,298]	8	hSpCas9	negative selection	6413877
226883843	226883866	1	-	27260156	EW8	viability	ACGATCATGCACAGAGTGACAGG	PSEN2	ENSG00000143801	-0.007655305786207628	[496]	[387,453,258,522]	0	hSpCas9	negative selection	6413878
226888958	226888981	1	+	27260156	EW8	viability	CATCATGATCAGTGCGCTCATGG	PSEN2	ENSG00000143801	0.22720133756277872	[559]	[659,619,360,525]	4	hSpCas9	negative selection	6413879
226889004	226889027	1	-	27260156	EW8	viability	ATGACCCACGCGGACCACTCTGG	PSEN2	ENSG00000143801	-0.22396413357964684	[296]	[215,287,172,153]	-4	hSpCas9	negative selection	6478136
226894023	226894046	1	-	27260156	EW8	viability	TGTAGAAGATGAAGTCCCCGAGG	PSEN2	ENSG00000143801	-0.09720031882732644	[354]	[532,204,186,192]	-2	hSpCas9	negative selection	6478137
226894000	226894023	1	+	27260156	EW8	viability	CACACAGGGGGCGTGAAGCTTGG	PSEN2	ENSG00000143801	-0.07078094936396795	[227]	[152,227,181,136]	-1	hSpCas9	negative selection	6478138
226883803	226883826	1	-	27260156	CORL105	viability	CGTGCTTCGCTCCGTATTTGAGG	PSEN2	ENSG00000143801	0.7531217028500763	[309]	[649,691,619,485]	9	hSpCas9	negative selection	6535128
226883843	226883866	1	-	27260156	CORL105	viability	ACGATCATGCACAGAGTGACAGG	PSEN2	ENSG00000143801	-0.28342696279997714	[496]	[437,431,557,495]	-5	hSpCas9	negative selection	6535129
226888958	226888981	1	+	27260156	CORL105	viability	CATCATGATCAGTGCGCTCATGG	PSEN2	ENSG00000143801	-0.09166613484266445	[559]	[649,553,677,590]	-2	hSpCas9	negative selection	6535130
226889004	226889027	1	-	27260156	CORL105	viability	ATGACCCACGCGGACCACTCTGG	PSEN2	ENSG00000143801	-0.042547934047542646	[296]	[335,388,328,293]	-1	hSpCas9	negative selection	6599387
226894023	226894046	1	-	27260156	CORL105	viability	TGTAGAAGATGAAGTCCCCGAGG	PSEN2	ENSG00000143801	-0.10103837862669324	[354]	[372,306,271,579]	-2	hSpCas9	negative selection	6599388
226894000	226894023	1	+	27260156	CORL105	viability	CACACAGGGGGCGTGAAGCTTGG	PSEN2	ENSG00000143801	0.3689811219645486	[227]	[420,385,300,265]	7	hSpCas9	negative selection	6599389
226883803	226883826	1	-	27260156	HS294T	viability	CGTGCTTCGCTCCGTATTTGAGG	PSEN2	ENSG00000143801	1.1779877067347133	[309]	[212,276,169,460]	9	hSpCas9	negative selection	6656379
226883843	226883866	1	-	27260156	HS294T	viability	ACGATCATGCACAGAGTGACAGG	PSEN2	ENSG00000143801	-0.4956907542352327	[496]	[140,131,101,175]	-6	hSpCas9	negative selection	6656380
226888958	226888981	1	+	27260156	HS294T	viability	CATCATGATCAGTGCGCTCATGG	PSEN2	ENSG00000143801	0.5253813842867369	[559]	[241,206,284,563]	7	hSpCas9	negative selection	6656381
226889004	226889027	1	-	27260156	HS294T	viability	ATGACCCACGCGGACCACTCTGG	PSEN2	ENSG00000143801	0.6662078790329186	[296]	[380,86,92,144]	8	hSpCas9	negative selection	6720638
226894023	226894046	1	-	27260156	HS294T	viability	TGTAGAAGATGAAGTCCCCGAGG	PSEN2	ENSG00000143801	-0.6236038639649222	[354]	[80,59,96,125]	-7	hSpCas9	negative selection	6720639
226894000	226894023	1	+	27260156	HS294T	viability	CACACAGGGGGCGTGAAGCTTGG	PSEN2	ENSG00000143801	-0.16783584080660385	[227]	[92,67,65,86]	-2	hSpCas9	negative selection	6720640
226883803	226883826	1	-	27260156	HCC44	viability	CGTGCTTCGCTCCGTATTTGAGG	PSEN2	ENSG00000143801	0.5610469766132338	[309]	[438,441,775,457]	8	hSpCas9	negative selection	6777630
226883843	226883866	1	-	27260156	HCC44	viability	ACGATCATGCACAGAGTGACAGG	PSEN2	ENSG00000143801	0.14904901650904556	[496]	[558,743,539,607]	2	hSpCas9	negative selection	6777631
226888958	226888981	1	+	27260156	HCC44	viability	CATCATGATCAGTGCGCTCATGG	PSEN2	ENSG00000143801	0.3715570017169616	[559]	[724,702,924,939]	6	hSpCas9	negative selection	6777632
226889004	226889027	1	-	27260156	HCC44	viability	ATGACCCACGCGGACCACTCTGG	PSEN2	ENSG00000143801	0.052253484013123463	[296]	[388,437,288,257]	0	hSpCas9	negative selection	6841889
226894023	226894046	1	-	27260156	HCC44	viability	TGTAGAAGATGAAGTCCCCGAGG	PSEN2	ENSG00000143801	-0.2228233740561692	[354]	[452,414,137,331]	-4	hSpCas9	negative selection	6841890
226894000	226894023	1	+	27260156	HCC44	viability	CACACAGGGGGCGTGAAGCTTGG	PSEN2	ENSG00000143801	0.19532414548409394	[227]	[296,229,456,233]	3	hSpCas9	negative selection	6841891
226883803	226883826	1	-	27260156	G402	viability	CGTGCTTCGCTCCGTATTTGAGG	PSEN2	ENSG00000143801	0.6626096981806228	[309]	[941,525,411,559]	7	hSpCas9	negative selection	6898881
226883843	226883866	1	-	27260156	G402	viability	ACGATCATGCACAGAGTGACAGG	PSEN2	ENSG00000143801	-0.2183408557356678	[496]	[699,635,225,551]	-3	hSpCas9	negative selection	6898882
226888958	226888981	1	+	27260156	G402	viability	CATCATGATCAGTGCGCTCATGG	PSEN2	ENSG00000143801	0.09118873604004124	[559]	[871,880,701,494]	1	hSpCas9	negative selection	6898883
226889004	226889027	1	-	27260156	G402	viability	ATGACCCACGCGGACCACTCTGG	PSEN2	ENSG00000143801	-0.4435405021278742	[296]	[267,319,208,270]	-5	hSpCas9	negative selection	6963140
226894023	226894046	1	-	27260156	G402	viability	TGTAGAAGATGAAGTCCCCGAGG	PSEN2	ENSG00000143801	0.42715598671066496	[354]	[180,341,481,1218]	5	hSpCas9	negative selection	6963141
226894000	226894023	1	+	27260156	G402	viability	CACACAGGGGGCGTGAAGCTTGG	PSEN2	ENSG00000143801	0.06369181800960766	[227]	[338,311,140,373]	0	hSpCas9	negative selection	6963142
226883803	226883826	1	-	27260156	L33	viability	CGTGCTTCGCTCCGTATTTGAGG	PSEN2	ENSG00000143801	0.7306782176723854	[309]	[597,174,337,492]	9	hSpCas9	negative selection	7020132
226883843	226883866	1	-	27260156	L33	viability	ACGATCATGCACAGAGTGACAGG	PSEN2	ENSG00000143801	-0.1275459429261538	[496]	[454,217,247,437]	-3	hSpCas9	negative selection	7020133
226888958	226888981	1	+	27260156	L33	viability	CATCATGATCAGTGCGCTCATGG	PSEN2	ENSG00000143801	0.20264624330060793	[559]	[599,252,438,662]	4	hSpCas9	negative selection	7020134
226889004	226889027	1	-	27260156	L33	viability	ATGACCCACGCGGACCACTCTGG	PSEN2	ENSG00000143801	-0.18980218102092672	[296]	[184,100,172,335]	-4	hSpCas9	negative selection	7084391
226894023	226894046	1	-	27260156	L33	viability	TGTAGAAGATGAAGTCCCCGAGG	PSEN2	ENSG00000143801	-0.0013030883309916863	[354]	[397,155,211,301]	0	hSpCas9	negative selection	7084392
226894000	226894023	1	+	27260156	L33	viability	CACACAGGGGGCGTGAAGCTTGG	PSEN2	ENSG00000143801	-0.06542110716204164	[227]	[187,83,171,205]	-1	hSpCas9	negative selection	7084393
226883803	226883826	1	-	27260156	K562	viability	CGTGCTTCGCTCCGTATTTGAGG	PSEN2	ENSG00000143801	0.6301292515377855	[309]	[671,468,319,279]	7	hSpCas9	negative selection	7141383
226883843	226883866	1	-	27260156	K562	viability	ACGATCATGCACAGAGTGACAGG	PSEN2	ENSG00000143801	-0.08564020290951106	[496]	[616,180,536,338]	-1	hSpCas9	negative selection	7141384
226888958	226888981	1	+	27260156	K562	viability	CATCATGATCAGTGCGCTCATGG	PSEN2	ENSG00000143801	0.39042960323254283	[559]	[357,659,1227,366]	5	hSpCas9	negative selection	7141385
226889004	226889027	1	-	27260156	K562	viability	ATGACCCACGCGGACCACTCTGG	PSEN2	ENSG00000143801	0.13202899510417676	[296]	[223,662,233,72]	1	hSpCas9	negative selection	7205642
226894023	226894046	1	-	27260156	K562	viability	TGTAGAAGATGAAGTCCCCGAGG	PSEN2	ENSG00000143801	-0.2666427206093596	[354]	[151,312,387,194]	-3	hSpCas9	negative selection	7205643
226894000	226894023	1	+	27260156	K562	viability	CACACAGGGGGCGTGAAGCTTGG	PSEN2	ENSG00000143801	0.717422493956996	[227]	[396,571,260,139]	8	hSpCas9	negative selection	7205644
226883803	226883826	1	-	27260156	HT29	viability	CGTGCTTCGCTCCGTATTTGAGG	PSEN2	ENSG00000143801	0.735285825573919	[309]	[658,635,648,570]	9	hSpCas9	negative selection	7262634
226883843	226883866	1	-	27260156	HT29	viability	ACGATCATGCACAGAGTGACAGG	PSEN2	ENSG00000143801	-0.3627699444206603	[496]	[591,415,333,530]	-6	hSpCas9	negative selection	7262635
226888958	226888981	1	+	27260156	HT29	viability	CATCATGATCAGTGCGCTCATGG	PSEN2	ENSG00000143801	0.05077113270914296	[559]	[787,792,791,483]	1	hSpCas9	negative selection	7262636
226889004	226889027	1	-	27260156	HT29	viability	ATGACCCACGCGGACCACTCTGG	PSEN2	ENSG00000143801	0.25995276583189075	[296]	[600,475,270,398]	5	hSpCas9	negative selection	7326893
226894023	226894046	1	-	27260156	HT29	viability	TGTAGAAGATGAAGTCCCCGAGG	PSEN2	ENSG00000143801	-0.3135754090732043	[354]	[320,297,510,260]	-6	hSpCas9	negative selection	7326894
226894000	226894023	1	+	27260156	HT29	viability	CACACAGGGGGCGTGAAGCTTGG	PSEN2	ENSG00000143801	0.05298969597202141	[227]	[271,374,189,313]	1	hSpCas9	negative selection	7326895
226883803	226883826	1	-	27260156	MHHES1	viability	CGTGCTTCGCTCCGTATTTGAGG	PSEN2	ENSG00000143801	0.7273173997148081	[309]	[742,465,702,430]	9	hSpCas9	negative selection	7383885
226883843	226883866	1	-	27260156	MHHES1	viability	ACGATCATGCACAGAGTGACAGG	PSEN2	ENSG00000143801	0.027312493039207297	[496]	[753,486,689,393]	0	hSpCas9	negative selection	7383886
226888958	226888981	1	+	27260156	MHHES1	viability	CATCATGATCAGTGCGCTCATGG	PSEN2	ENSG00000143801	-0.27914351829526457	[559]	[565,459,457,569]	-5	hSpCas9	negative selection	7383887
226889004	226889027	1	-	27260156	MHHES1	viability	ATGACCCACGCGGACCACTCTGG	PSEN2	ENSG00000143801	0.11909739110286666	[296]	[378,352,342,368]	2	hSpCas9	negative selection	7448144
226894023	226894046	1	-	27260156	MHHES1	viability	TGTAGAAGATGAAGTCCCCGAGG	PSEN2	ENSG00000143801	-0.05429722304181317	[354]	[391,359,505,293]	-1	hSpCas9	negative selection	7448145
226894000	226894023	1	+	27260156	MHHES1	viability	CACACAGGGGGCGTGAAGCTTGG	PSEN2	ENSG00000143801	0.09112347431977119	[227]	[208,311,309,256]	1	hSpCas9	negative selection	7448146
226883803	226883826	1	-	27260156	MEWO	viability	CGTGCTTCGCTCCGTATTTGAGG	PSEN2	ENSG00000143801	0.5731039897444176	[309]	[543,252,519]	9	hSpCas9	negative selection	7505136
226883843	226883866	1	-	27260156	MEWO	viability	ACGATCATGCACAGAGTGACAGG	PSEN2	ENSG00000143801	-0.6371119036619949	[496]	[420,197,301]	-8	hSpCas9	negative selection	7505137
226888958	226888981	1	+	27260156	MEWO	viability	CATCATGATCAGTGCGCTCATGG	PSEN2	ENSG00000143801	0.32004207221438064	[559]	[790,551,645]	6	hSpCas9	negative selection	7505138
226889004	226889027	1	-	27260156	MEWO	viability	ATGACCCACGCGGACCACTCTGG	PSEN2	ENSG00000143801	0.05492969085647914	[296]	[233,346,273]	1	hSpCas9	negative selection	7569395
226894023	226894046	1	-	27260156	MEWO	viability	TGTAGAAGATGAAGTCCCCGAGG	PSEN2	ENSG00000143801	-0.39430485192228476	[354]	[368,164,246]	-7	hSpCas9	negative selection	7569396
226894000	226894023	1	+	27260156	MEWO	viability	CACACAGGGGGCGTGAAGCTTGG	PSEN2	ENSG00000143801	0.3670303819435623	[227]	[385,219,240]	7	hSpCas9	negative selection	7569397
226883803	226883826	1	-	27260156	LNCAPCLONEFGC	viability	CGTGCTTCGCTCCGTATTTGAGG	PSEN2	ENSG00000143801	0.6822787477605374	[309]	[432,427,544,411]	9	hSpCas9	negative selection	7626387
226883843	226883866	1	-	27260156	LNCAPCLONEFGC	viability	ACGATCATGCACAGAGTGACAGG	PSEN2	ENSG00000143801	-0.2360066513876597	[496]	[431,287,502,328]	-4	hSpCas9	negative selection	7626388
226888958	226888981	1	+	27260156	LNCAPCLONEFGC	viability	CATCATGATCAGTGCGCTCATGG	PSEN2	ENSG00000143801	0.020451305188509017	[559]	[591,281,624,588]	0	hSpCas9	negative selection	7626389
226889004	226889027	1	-	27260156	LNCAPCLONEFGC	viability	ATGACCCACGCGGACCACTCTGG	PSEN2	ENSG00000143801	0.02444782409219659	[296]	[205,200,357,347]	0	hSpCas9	negative selection	7690646
226894023	226894046	1	-	27260156	LNCAPCLONEFGC	viability	TGTAGAAGATGAAGTCCCCGAGG	PSEN2	ENSG00000143801	-0.366400279304183	[354]	[175,242,299,287]	-5	hSpCas9	negative selection	7690647
226894000	226894023	1	+	27260156	LNCAPCLONEFGC	viability	CACACAGGGGGCGTGAAGCTTGG	PSEN2	ENSG00000143801	0.0006757407502593349	[227]	[237,241,169,167]	0	hSpCas9	negative selection	7690648
226883803	226883826	1	-	27260156	PANC0327	viability	CGTGCTTCGCTCCGTATTTGAGG	PSEN2	ENSG00000143801	0.9647553019625156	[309]	[622,356,578,620]	9	hSpCas9	negative selection	7747638
226883843	226883866	1	-	27260156	PANC0327	viability	ACGATCATGCACAGAGTGACAGG	PSEN2	ENSG00000143801	0.08352075594409415	[496]	[722,202,410,588]	1	hSpCas9	negative selection	7747639
226888958	226888981	1	+	27260156	PANC0327	viability	CATCATGATCAGTGCGCTCATGG	PSEN2	ENSG00000143801	-0.09210223008834789	[559]	[361,316,816,381]	-1	hSpCas9	negative selection	7747640
226889004	226889027	1	-	27260156	PANC0327	viability	ATGACCCACGCGGACCACTCTGG	PSEN2	ENSG00000143801	-0.13850432709847715	[296]	[377,107,255,244]	-2	hSpCas9	negative selection	7811897
226894023	226894046	1	-	27260156	PANC0327	viability	TGTAGAAGATGAAGTCCCCGAGG	PSEN2	ENSG00000143801	-0.008383516314997175	[354]	[436,229,349,257]	0	hSpCas9	negative selection	7811898
226894000	226894023	1	+	27260156	PANC0327	viability	CACACAGGGGGCGTGAAGCTTGG	PSEN2	ENSG00000143801	-0.17197773819491302	[227]	[347,154,128,103]	-3	hSpCas9	negative selection	7811899
226883803	226883826	1	-	27260156	NCIH2009	viability	CGTGCTTCGCTCCGTATTTGAGG	PSEN2	ENSG00000143801	0.6618158887290916	[309]	[829,526,728]	8	hSpCas9	negative selection	7868889
226883843	226883866	1	-	27260156	NCIH2009	viability	ACGATCATGCACAGAGTGACAGG	PSEN2	ENSG00000143801	-0.23305060906704977	[496]	[566,519,680]	-3	hSpCas9	negative selection	7868890
226888958	226888981	1	+	27260156	NCIH2009	viability	CATCATGATCAGTGCGCTCATGG	PSEN2	ENSG00000143801	0.305435145129768	[559]	[1377,872,730]	4	hSpCas9	negative selection	7868891
226889004	226889027	1	-	27260156	NCIH2009	viability	ATGACCCACGCGGACCACTCTGG	PSEN2	ENSG00000143801	-0.20118432472638736	[296]	[588,266,272]	-3	hSpCas9	negative selection	7933148
226894023	226894046	1	-	27260156	NCIH2009	viability	TGTAGAAGATGAAGTCCCCGAGG	PSEN2	ENSG00000143801	0.44562945527423437	[354]	[925,556,593]	6	hSpCas9	negative selection	7933149
226894000	226894023	1	+	27260156	NCIH2009	viability	CACACAGGGGGCGTGAAGCTTGG	PSEN2	ENSG00000143801	0.09630084312929665	[227]	[464,320,259]	1	hSpCas9	negative selection	7933150
226883803	226883826	1	-	27260156	NCIH1373	viability	CGTGCTTCGCTCCGTATTTGAGG	PSEN2	ENSG00000143801	1.0392622490309746	[309]	[764,593,779,192]	9	hSpCas9	negative selection	7990140
226883843	226883866	1	-	27260156	NCIH1373	viability	ACGATCATGCACAGAGTGACAGG	PSEN2	ENSG00000143801	-0.05976395750175789	[496]	[574,425,634,134]	0	hSpCas9	negative selection	7990141
226888958	226888981	1	+	27260156	NCIH1373	viability	CATCATGATCAGTGCGCTCATGG	PSEN2	ENSG00000143801	0.9463066938524675	[559]	[1163,1366,1229,271]	8	hSpCas9	negative selection	7990142
226889004	226889027	1	-	27260156	NCIH1373	viability	ATGACCCACGCGGACCACTCTGG	PSEN2	ENSG00000143801	0.33219088760984244	[296]	[367,431,539,82]	3	hSpCas9	negative selection	8054399
226894023	226894046	1	-	27260156	NCIH1373	viability	TGTAGAAGATGAAGTCCCCGAGG	PSEN2	ENSG00000143801	-0.16456478255781054	[354]	[481,113,321,146]	-2	hSpCas9	negative selection	8054400
226894000	226894023	1	+	27260156	NCIH1373	viability	CACACAGGGGGCGTGAAGCTTGG	PSEN2	ENSG00000143801	-0.009039268745617335	[227]	[390,165,247,62]	0	hSpCas9	negative selection	8054401
226883803	226883826	1	-	27260156	PATU8902	viability	CGTGCTTCGCTCCGTATTTGAGG	PSEN2	ENSG00000143801	1.608806505523921	[309]	[1266,1730,404,2197]	9	hSpCas9	negative selection	8111391
226883843	226883866	1	-	27260156	PATU8902	viability	ACGATCATGCACAGAGTGACAGG	PSEN2	ENSG00000143801	0.46719802887295114	[496]	[1264,1081,533,1056]	5	hSpCas9	negative selection	8111392
226888958	226888981	1	+	27260156	PATU8902	viability	CATCATGATCAGTGCGCTCATGG	PSEN2	ENSG00000143801	-0.32371459261395774	[559]	[687,633,640,504]	-3	hSpCas9	negative selection	8111393
226889004	226889027	1	-	27260156	PATU8902	viability	ATGACCCACGCGGACCACTCTGG	PSEN2	ENSG00000143801	-0.7075903829189978	[296]	[281,405,130,219]	-6	hSpCas9	negative selection	8175650
226894023	226894046	1	-	27260156	PATU8902	viability	TGTAGAAGATGAAGTCCCCGAGG	PSEN2	ENSG00000143801	0.6948149605515134	[354]	[765,755,683,1048]	7	hSpCas9	negative selection	8175651
226894000	226894023	1	+	27260156	PATU8902	viability	CACACAGGGGGCGTGAAGCTTGG	PSEN2	ENSG00000143801	0.4763696891507696	[227]	[138,558,592,436]	5	hSpCas9	negative selection	8175652
226883803	226883826	1	-	27260156	PANC1	viability	CGTGCTTCGCTCCGTATTTGAGG	PSEN2	ENSG00000143801	0.9518297824287594	[309]	[570,807,425,334]	9	hSpCas9	negative selection	8232642
226883843	226883866	1	-	27260156	PANC1	viability	ACGATCATGCACAGAGTGACAGG	PSEN2	ENSG00000143801	-0.20594461902316347	[496]	[289,394,495,310]	-3	hSpCas9	negative selection	8232643
226888958	226888981	1	+	27260156	PANC1	viability	CATCATGATCAGTGCGCTCATGG	PSEN2	ENSG00000143801	0.23316775444032833	[559]	[710,642,595,350]	4	hSpCas9	negative selection	8232644
226889004	226889027	1	-	27260156	PANC1	viability	ATGACCCACGCGGACCACTCTGG	PSEN2	ENSG00000143801	0.4291225924263481	[296]	[256,452,421,272]	7	hSpCas9	negative selection	8296901
226894023	226894046	1	-	27260156	PANC1	viability	TGTAGAAGATGAAGTCCCCGAGG	PSEN2	ENSG00000143801	-0.095333301791868	[354]	[268,255,251,343]	-1	hSpCas9	negative selection	8296902
226894000	226894023	1	+	27260156	PANC1	viability	CACACAGGGGGCGTGAAGCTTGG	PSEN2	ENSG00000143801	-0.0035989683594377375	[227]	[247,214,132,185]	0	hSpCas9	negative selection	8296903
226883803	226883826	1	-	27260156	PANC0813	viability	CGTGCTTCGCTCCGTATTTGAGG	PSEN2	ENSG00000143801	0.8836030257747394	[309]	[786,539,765,607]	9	hSpCas9	negative selection	8353893
226883843	226883866	1	-	27260156	PANC0813	viability	ACGATCATGCACAGAGTGACAGG	PSEN2	ENSG00000143801	0.23565506062775865	[496]	[782,775,572,627]	4	hSpCas9	negative selection	8353894
226888958	226888981	1	+	27260156	PANC0813	viability	CATCATGATCAGTGCGCTCATGG	PSEN2	ENSG00000143801	0.36487849387877036	[559]	[1020,761,879,745]	6	hSpCas9	negative selection	8353895
226889004	226889027	1	-	27260156	PANC0813	viability	ATGACCCACGCGGACCACTCTGG	PSEN2	ENSG00000143801	0.03783680507807763	[296]	[354,374,401,302]	0	hSpCas9	negative selection	8418152
226894023	226894046	1	-	27260156	PANC0813	viability	TGTAGAAGATGAAGTCCCCGAGG	PSEN2	ENSG00000143801	0.16767101457231778	[354]	[395,672,528,278]	2	hSpCas9	negative selection	8418153
226894000	226894023	1	+	27260156	PANC0813	viability	CACACAGGGGGCGTGAAGCTTGG	PSEN2	ENSG00000143801	-0.20034416318906456	[227]	[233,249,283,167]	-3	hSpCas9	negative selection	8418154
226883803	226883826	1	-	27260156	RDES	viability	CGTGCTTCGCTCCGTATTTGAGG	PSEN2	ENSG00000143801	0.6039883808350068	[309]	[519,537,521,578]	8	hSpCas9	negative selection	8475144
226883843	226883866	1	-	27260156	RDES	viability	ACGATCATGCACAGAGTGACAGG	PSEN2	ENSG00000143801	-0.1500773927590916	[496]	[435,445,570,635]	-3	hSpCas9	negative selection	8475145
226888958	226888981	1	+	27260156	RDES	viability	CATCATGATCAGTGCGCTCATGG	PSEN2	ENSG00000143801	-0.3104311526528827	[559]	[516,409,636,509]	-5	hSpCas9	negative selection	8475146
226889004	226889027	1	-	27260156	RDES	viability	ATGACCCACGCGGACCACTCTGG	PSEN2	ENSG00000143801	0.04921837113795313	[296]	[282,275,463,416]	0	hSpCas9	negative selection	8539403
226894023	226894046	1	-	27260156	RDES	viability	TGTAGAAGATGAAGTCCCCGAGG	PSEN2	ENSG00000143801	-0.423358644134508	[354]	[251,333,270,367]	-6	hSpCas9	negative selection	8539404
226894000	226894023	1	+	27260156	RDES	viability	CACACAGGGGGCGTGAAGCTTGG	PSEN2	ENSG00000143801	-0.05881546714775965	[227]	[196,298,269,238]	-1	hSpCas9	negative selection	8539405
226883803	226883826	1	-	27260156	PC3	viability	CGTGCTTCGCTCCGTATTTGAGG	PSEN2	ENSG00000143801	0.6243804898813843	[309]	[278,601,786,388]	9	hSpCas9	negative selection	8596395
226883843	226883866	1	-	27260156	PC3	viability	ACGATCATGCACAGAGTGACAGG	PSEN2	ENSG00000143801	0.040353243766910296	[496]	[249,602,722,616]	0	hSpCas9	negative selection	8596396
226888958	226888981	1	+	27260156	PC3	viability	CATCATGATCAGTGCGCTCATGG	PSEN2	ENSG00000143801	-0.08665198433333948	[559]	[283,683,754,518]	-2	hSpCas9	negative selection	8596397
226889004	226889027	1	-	27260156	PC3	viability	ATGACCCACGCGGACCACTCTGG	PSEN2	ENSG00000143801	-0.19247043809582887	[296]	[198,183,327,356]	-4	hSpCas9	negative selection	8660654
226894023	226894046	1	-	27260156	PC3	viability	TGTAGAAGATGAAGTCCCCGAGG	PSEN2	ENSG00000143801	-0.8747286336750726	[354]	[114,108,333,294]	-9	hSpCas9	negative selection	8660655
226894000	226894023	1	+	27260156	PC3	viability	CACACAGGGGGCGTGAAGCTTGG	PSEN2	ENSG00000143801	0.3280457700891932	[227]	[177,382,376,249]	7	hSpCas9	negative selection	8660656
226883803	226883826	1	-	27260156	PATU8988T	viability	CGTGCTTCGCTCCGTATTTGAGG	PSEN2	ENSG00000143801	0.5398235368916563	[309]	[426,287,654,347]	8	hSpCas9	negative selection	8717646
226883843	226883866	1	-	27260156	PATU8988T	viability	ACGATCATGCACAGAGTGACAGG	PSEN2	ENSG00000143801	-0.20979258171630882	[496]	[374,418,468,395]	-4	hSpCas9	negative selection	8717647
226888958	226888981	1	+	27260156	PATU8988T	viability	CATCATGATCAGTGCGCTCATGG	PSEN2	ENSG00000143801	-0.11393810771502222	[559]	[482,704,377,450]	-2	hSpCas9	negative selection	8717648
226889004	226889027	1	-	27260156	PATU8988T	viability	ATGACCCACGCGGACCACTCTGG	PSEN2	ENSG00000143801	0.01809813814729766	[296]	[151,175,493,329]	0	hSpCas9	negative selection	8781905
226894023	226894046	1	-	27260156	PATU8988T	viability	TGTAGAAGATGAAGTCCCCGAGG	PSEN2	ENSG00000143801	-0.19362435334638034	[354]	[242,451,181,341]	-3	hSpCas9	negative selection	8781906
226894000	226894023	1	+	27260156	PATU8988T	viability	CACACAGGGGGCGTGAAGCTTGG	PSEN2	ENSG00000143801	0.43547861304209334	[227]	[272,311,298,309]	7	hSpCas9	negative selection	8781907
226883803	226883826	1	-	27260156	T47D	viability	CGTGCTTCGCTCCGTATTTGAGG	PSEN2	ENSG00000143801	0.5506400971937028	[309]	[516,506,544,548]	9	hSpCas9	negative selection	8838897
226883843	226883866	1	-	27260156	T47D	viability	ACGATCATGCACAGAGTGACAGG	PSEN2	ENSG00000143801	-0.18134901372514917	[496]	[522,434,554,535]	-4	hSpCas9	negative selection	8838898
226888958	226888981	1	+	27260156	T47D	viability	CATCATGATCAGTGCGCTCATGG	PSEN2	ENSG00000143801	0.05029245366180518	[559]	[660,636,696,710]	1	hSpCas9	negative selection	8838899
226889004	226889027	1	-	27260156	T47D	viability	ATGACCCACGCGGACCACTCTGG	PSEN2	ENSG00000143801	-0.08393567481907083	[296]	[376,351,266,307]	-2	hSpCas9	negative selection	8903156
226894023	226894046	1	-	27260156	T47D	viability	TGTAGAAGATGAAGTCCCCGAGG	PSEN2	ENSG00000143801	-0.40668632946334343	[354]	[349,270,306,323]	-7	hSpCas9	negative selection	8903157
226894000	226894023	1	+	27260156	T47D	viability	CACACAGGGGGCGTGAAGCTTGG	PSEN2	ENSG00000143801	0.02881725365774357	[227]	[245,193,351,297]	0	hSpCas9	negative selection	8903158
226883803	226883826	1	-	27260156	SU8686	viability	CGTGCTTCGCTCCGTATTTGAGG	PSEN2	ENSG00000143801	0.6553166282787352	[309]	[410,493,387,674]	9	hSpCas9	negative selection	8960148
226883843	226883866	1	-	27260156	SU8686	viability	ACGATCATGCACAGAGTGACAGG	PSEN2	ENSG00000143801	-0.13627280726506757	[496]	[480,402,381,538]	-2	hSpCas9	negative selection	8960149
226888958	226888981	1	+	27260156	SU8686	viability	CATCATGATCAGTGCGCTCATGG	PSEN2	ENSG00000143801	0.2982530349008625	[559]	[581,609,840,724]	5	hSpCas9	negative selection	8960150
226889004	226889027	1	-	27260156	SU8686	viability	ATGACCCACGCGGACCACTCTGG	PSEN2	ENSG00000143801	0.1833102515625838	[296]	[247,315,485,294]	3	hSpCas9	negative selection	9024407
226894023	226894046	1	-	27260156	SU8686	viability	TGTAGAAGATGAAGTCCCCGAGG	PSEN2	ENSG00000143801	0.13079877655474942	[354]	[321,379,464,380]	2	hSpCas9	negative selection	9024408
226894000	226894023	1	+	27260156	SU8686	viability	CACACAGGGGGCGTGAAGCTTGG	PSEN2	ENSG00000143801	-0.059613431345914236	[227]	[329,177,165,175]	-1	hSpCas9	negative selection	9024409
226883803	226883826	1	-	27260156	SKES1	viability	CGTGCTTCGCTCCGTATTTGAGG	PSEN2	ENSG00000143801	0.49147919526720224	[309]	[470,561,385,346]	8	hSpCas9	negative selection	9081399
226883843	226883866	1	-	27260156	SKES1	viability	ACGATCATGCACAGAGTGACAGG	PSEN2	ENSG00000143801	-0.030101937810008216	[496]	[583,408,434,510]	0	hSpCas9	negative selection	9081400
226888958	226888981	1	+	27260156	SKES1	viability	CATCATGATCAGTGCGCTCATGG	PSEN2	ENSG00000143801	0.14380338008244103	[559]	[746,613,645,487]	3	hSpCas9	negative selection	9081401
226889004	226889027	1	-	27260156	SKES1	viability	ATGACCCACGCGGACCACTCTGG	PSEN2	ENSG00000143801	-0.2962438199087192	[296]	[244,272,204,243]	-6	hSpCas9	negative selection	9145658
226894023	226894046	1	-	27260156	SKES1	viability	TGTAGAAGATGAAGTCCCCGAGG	PSEN2	ENSG00000143801	-0.21844011133536306	[354]	[357,343,360,177]	-5	hSpCas9	negative selection	9145659
226894000	226894023	1	+	27260156	SKES1	viability	CACACAGGGGGCGTGAAGCTTGG	PSEN2	ENSG00000143801	0.14450859033315155	[227]	[195,275,254,268]	3	hSpCas9	negative selection	9145660
226883803	226883826	1	-	27260156	TOV112D	viability	CGTGCTTCGCTCCGTATTTGAGG	PSEN2	ENSG00000143801	0.326170542152842	[309]	[542,553,274,241]	6	hSpCas9	negative selection	9202650
226883843	226883866	1	-	27260156	TOV112D	viability	ACGATCATGCACAGAGTGACAGG	PSEN2	ENSG00000143801	-0.01857723054582102	[496]	[510,570,338,562]	0	hSpCas9	negative selection	9202651
226888958	226888981	1	+	27260156	TOV112D	viability	CATCATGATCAGTGCGCTCATGG	PSEN2	ENSG00000143801	0.2791453750958567	[559]	[671,744,696,623]	5	hSpCas9	negative selection	9202652
226889004	226889027	1	-	27260156	TOV112D	viability	ATGACCCACGCGGACCACTCTGG	PSEN2	ENSG00000143801	-0.13725638824223685	[296]	[156,497,243,229]	-3	hSpCas9	negative selection	9266909
226894023	226894046	1	-	27260156	TOV112D	viability	TGTAGAAGATGAAGTCCCCGAGG	PSEN2	ENSG00000143801	-0.34775243485097856	[354]	[251,413,204,276]	-6	hSpCas9	negative selection	9266910
226894000	226894023	1	+	27260156	TOV112D	viability	CACACAGGGGGCGTGAAGCTTGG	PSEN2	ENSG00000143801	0.592117153522614	[227]	[201,436,504,245]	9	hSpCas9	negative selection	9266911
226883803	226883826	1	-	27260156	TC71	viability	CGTGCTTCGCTCCGTATTTGAGG	PSEN2	ENSG00000143801	0.40182139988064225	[309]	[470,411,418,454]	8	hSpCas9	negative selection	9323901
226883843	226883866	1	-	27260156	TC71	viability	ACGATCATGCACAGAGTGACAGG	PSEN2	ENSG00000143801	-0.12433932999670455	[496]	[439,428,580,503]	-3	hSpCas9	negative selection	9323902
226888958	226888981	1	+	27260156	TC71	viability	CATCATGATCAGTGCGCTCATGG	PSEN2	ENSG00000143801	0.2315477472847507	[559]	[588,758,673,806]	6	hSpCas9	negative selection	9323903
226889004	226889027	1	-	27260156	TC71	viability	ATGACCCACGCGGACCACTCTGG	PSEN2	ENSG00000143801	0.09672297681949171	[296]	[428,310,327,288]	2	hSpCas9	negative selection	9388160
226894023	226894046	1	-	27260156	TC71	viability	TGTAGAAGATGAAGTCCCCGAGG	PSEN2	ENSG00000143801	0.016472798368184494	[354]	[344,530,340,320]	0	hSpCas9	negative selection	9388161
226894000	226894023	1	+	27260156	TC71	viability	CACACAGGGGGCGTGAAGCTTGG	PSEN2	ENSG00000143801	-0.2054477618451782	[227]	[225,191,180,251]	-5	hSpCas9	negative selection	9388162
226883803	226883826	1	-	27260156	TC32	viability	CGTGCTTCGCTCCGTATTTGAGG	PSEN2	ENSG00000143801	0.6322968959765802	[309]	[447,378,457,525]	9	hSpCas9	negative selection	9445152
226883843	226883866	1	-	27260156	TC32	viability	ACGATCATGCACAGAGTGACAGG	PSEN2	ENSG00000143801	-0.22382175275394883	[496]	[407,324,406,466]	-4	hSpCas9	negative selection	9445153
226888958	226888981	1	+	27260156	TC32	viability	CATCATGATCAGTGCGCTCATGG	PSEN2	ENSG00000143801	-0.07432940208340191	[559]	[565,287,601,609]	-1	hSpCas9	negative selection	9445154
226889004	226889027	1	-	27260156	TC32	viability	ATGACCCACGCGGACCACTCTGG	PSEN2	ENSG00000143801	-0.31782739578134944	[296]	[313,80,338,210]	-5	hSpCas9	negative selection	9509411
226894023	226894046	1	-	27260156	TC32	viability	TGTAGAAGATGAAGTCCCCGAGG	PSEN2	ENSG00000143801	-0.28756181665241703	[354]	[257,157,406,326]	-5	hSpCas9	negative selection	9509412
226894000	226894023	1	+	27260156	TC32	viability	CACACAGGGGGCGTGAAGCTTGG	PSEN2	ENSG00000143801	-0.44927481873127495	[227]	[133,79,221,230]	-7	hSpCas9	negative selection	9509413
226881916	226881939	1	+	27869803	HPAFII	viability after 27 days	ATTCATGGCCTCTGACAGCGAGG	PSEN2	ENSG00000143801	-0.09510266737237316	[168]	[158,19,NaN]	0	hSpCas9	negative selection	9532416
226883891	226883914	1	+	27869803	HPAFII	viability after 27 days	CGCTTCTACACAGAGAAGAATGG	PSEN2	ENSG00000143801	0.5489025698728316	[709]	[628,476,NaN]	4	hSpCas9	negative selection	9532417
226885594	226885617	1	-	27869803	HPAFII	viability after 27 days	CATGATGAGGGTGTTCAGCACGG	PSEN2	ENSG00000143801	-0.1806452768519854	[438]	[129,264,NaN]	-1	hSpCas9	negative selection	9532418
226888096	226888119	1	-	27869803	HPAFII	viability after 27 days	AAGACATGATCAACCAGCCATGG	PSEN2	ENSG00000143801	1.2710163668036965	[229]	[251,324,NaN]	9	hSpCas9	negative selection	9532419
226888838	226888861	1	+	27869803	HPAFII	viability after 27 days	CAAGACCTACAATGTGGCCATGG	PSEN2	ENSG00000143801	0.19027058266559205	[380]	[281,183,NaN]	1	hSpCas9	negative selection	9532420
226890072	226890095	1	+	27869803	HPAFII	viability after 27 days	AATGCTGGTAGAAACTGCCCAGG	PSEN2	ENSG00000143801	-0.13425879944215913	[25]	[12,11,NaN]	-1	hSpCas9	negative selection	9532421
226881916	226881939	1	+	27869803	HPAFII	viability after 15 days	ATTCATGGCCTCTGACAGCGAGG	PSEN2	ENSG00000143801	0.21314960728008986	[168]	[360,116,NaN]	2	hSpCas9	negative selection	9614865
226883891	226883914	1	+	27869803	HPAFII	viability after 15 days	CGCTTCTACACAGAGAAGAATGG	PSEN2	ENSG00000143801	0.17698823507768924	[709]	[1424,512,NaN]	2	hSpCas9	negative selection	9614866
226885594	226885617	1	-	27869803	HPAFII	viability after 15 days	CATGATGAGGGTGTTCAGCACGG	PSEN2	ENSG00000143801	0.16818182919468283	[438]	[613,477,NaN]	2	hSpCas9	negative selection	9614867
226888096	226888119	1	-	27869803	HPAFII	viability after 15 days	AAGACATGATCAACCAGCCATGG	PSEN2	ENSG00000143801	0.6923640303294072	[229]	[449,367,NaN]	7	hSpCas9	negative selection	9614868
226888838	226888861	1	+	27869803	HPAFII	viability after 15 days	CAAGACCTACAATGTGGCCATGG	PSEN2	ENSG00000143801	0.4045040557895908	[380]	[623,490,NaN]	4	hSpCas9	negative selection	9614869
226890072	226890095	1	+	27869803	HPAFII	viability after 15 days	AATGCTGGTAGAAACTGCCCAGG	PSEN2	ENSG00000143801	0.4768648258158956	[25]	[94,3,NaN]	5	hSpCas9	negative selection	9614870
226881916	226881939	1	+	27869803	ASPC1	viability after 36 days	ATTCATGGCCTCTGACAGCGAGG	PSEN2	ENSG00000143801	0.47120657098232815	[472]	[26,451,190]	5	hSpCas9	negative selection	9697314
226883891	226883914	1	+	27869803	ASPC1	viability after 36 days	CGCTTCTACACAGAGAAGAATGG	PSEN2	ENSG00000143801	0.2931401550086248	[1490]	[587,978,394]	3	hSpCas9	negative selection	9697315
226885594	226885617	1	-	27869803	ASPC1	viability after 36 days	CATGATGAGGGTGTTCAGCACGG	PSEN2	ENSG00000143801	0.06599856385716907	[974]	[456,112,474]	0	hSpCas9	negative selection	9697316
226888096	226888119	1	-	27869803	ASPC1	viability after 36 days	AAGACATGATCAACCAGCCATGG	PSEN2	ENSG00000143801	-0.1067904641219749	[627]	[405,188,70]	-1	hSpCas9	negative selection	9697317
226888838	226888861	1	+	27869803	ASPC1	viability after 36 days	CAAGACCTACAATGTGGCCATGG	PSEN2	ENSG00000143801	0.07390312693736878	[913]	[436,242,334]	0	hSpCas9	negative selection	9697318
226890072	226890095	1	+	27869803	ASPC1	viability after 36 days	AATGCTGGTAGAAACTGCCCAGG	PSEN2	ENSG00000143801	-0.8439149896491314	[100]	[9,0,40]	-7	hSpCas9	negative selection	9697319
226881916	226881939	1	+	27869803	PATU8988S	viability after 35 days	ATTCATGGCCTCTGACAGCGAGG	PSEN2	ENSG00000143801	-0.4977743451268064	[353]	[87,113,NaN]	-5	hSpCas9	negative selection	9779763
226883891	226883914	1	+	27869803	PATU8988S	viability after 35 days	CGCTTCTACACAGAGAAGAATGG	PSEN2	ENSG00000143801	0.0568023367805357	[1275]	[554,513,NaN]	0	hSpCas9	negative selection	9779764
226885594	226885617	1	-	27869803	PATU8988S	viability after 35 days	CATGATGAGGGTGTTCAGCACGG	PSEN2	ENSG00000143801	-0.13898286709991786	[837]	[309,302,NaN]	-1	hSpCas9	negative selection	9779765
226888096	226888119	1	-	27869803	PATU8988S	viability after 35 days	AAGACATGATCAACCAGCCATGG	PSEN2	ENSG00000143801	0.8234486325121291	[541]	[295,476,NaN]	8	hSpCas9	negative selection	9779766
226888838	226888861	1	+	27869803	PATU8988S	viability after 35 days	CAAGACCTACAATGTGGCCATGG	PSEN2	ENSG00000143801	0.60684325713671	[677]	[352,478,NaN]	6	hSpCas9	negative selection	9779767
226890072	226890095	1	+	27869803	PATU8988S	viability after 35 days	AATGCTGGTAGAAACTGCCCAGG	PSEN2	ENSG00000143801	1.5912397403848613	[82]	[197,2,NaN]	9	hSpCas9	negative selection	9779768
226881916	226881939	1	+	27869803	PATU8988S	viability after 31 days	ATTCATGGCCTCTGACAGCGAGG	PSEN2	ENSG00000143801	0.022662473472958466	[353]	[94,204,NaN]	0	hSpCas9	negative selection	9862212
226883891	226883914	1	+	27869803	PATU8988S	viability after 31 days	CGCTTCTACACAGAGAAGAATGG	PSEN2	ENSG00000143801	0.22494796611443535	[1275]	[635,541,NaN]	2	hSpCas9	negative selection	9862213
226885594	226885617	1	-	27869803	PATU8988S	viability after 31 days	CATGATGAGGGTGTTCAGCACGG	PSEN2	ENSG00000143801	-0.0830037756129186	[837]	[241,408,NaN]	-1	hSpCas9	negative selection	9862214
226888096	226888119	1	-	27869803	PATU8988S	viability after 31 days	AAGACATGATCAACCAGCCATGG	PSEN2	ENSG00000143801	0.4801532980976645	[541]	[216,408,NaN]	6	hSpCas9	negative selection	9862215
226888838	226888861	1	+	27869803	PATU8988S	viability after 31 days	CAAGACCTACAATGTGGCCATGG	PSEN2	ENSG00000143801	0.7148571567738247	[677]	[287,641,NaN]	8	hSpCas9	negative selection	9862216
226890072	226890095	1	+	27869803	PATU8988S	viability after 31 days	AATGCTGGTAGAAACTGCCCAGG	PSEN2	ENSG00000143801	0.4123456208012404	[82]	[69,10,NaN]	5	hSpCas9	negative selection	9862217
226881916	226881939	1	+	27869803	HPAFII	viability after 35 days	ATTCATGGCCTCTGACAGCGAGG	PSEN2	ENSG00000143801	-0.3973006220121468	[168]	[103,20,NaN]	-2	hSpCas9	negative selection	9944661
226883891	226883914	1	+	27869803	HPAFII	viability after 35 days	CGCTTCTACACAGAGAAGAATGG	PSEN2	ENSG00000143801	0.9095709196788486	[709]	[709,635,NaN]	6	hSpCas9	negative selection	9944662
226885594	226885617	1	-	27869803	HPAFII	viability after 35 days	CATGATGAGGGTGTTCAGCACGG	PSEN2	ENSG00000143801	-1.3347437131548876	[438]	[73,103,NaN]	-6	hSpCas9	negative selection	9944663
226888096	226888119	1	-	27869803	HPAFII	viability after 35 days	AAGACATGATCAACCAGCCATGG	PSEN2	ENSG00000143801	1.5047857345653128	[229]	[122,563,NaN]	8	hSpCas9	negative selection	9944664
226888838	226888861	1	+	27869803	HPAFII	viability after 35 days	CAAGACCTACAATGTGGCCATGG	PSEN2	ENSG00000143801	0.21189611041456735	[380]	[189,260,NaN]	1	hSpCas9	negative selection	9944665
226890072	226890095	1	+	27869803	HPAFII	viability after 35 days	AATGCTGGTAGAAACTGCCCAGG	PSEN2	ENSG00000143801	-2.4486793073884785	[25]	[0,3,NaN]	-8	hSpCas9	negative selection	9944666
226881916	226881939	1	+	27869803	HPAFII	viability after 31 days	ATTCATGGCCTCTGACAGCGAGG	PSEN2	ENSG00000143801	-0.5846775954540274	[168]	[90,32,NaN]	-4	hSpCas9	negative selection	10027110
226883891	226883914	1	+	27869803	HPAFII	viability after 31 days	CGCTTCTACACAGAGAAGAATGG	PSEN2	ENSG00000143801	0.6151214198212185	[709]	[784,419,NaN]	4	hSpCas9	negative selection	10027111
226885594	226885617	1	-	27869803	HPAFII	viability after 31 days	CATGATGAGGGTGTTCAGCACGG	PSEN2	ENSG00000143801	-0.9125420992870591	[438]	[38,230,NaN]	-5	hSpCas9	negative selection	10027112
226888096	226888119	1	-	27869803	HPAFII	viability after 31 days	AAGACATGATCAACCAGCCATGG	PSEN2	ENSG00000143801	1.2629746893375444	[229]	[181,448,NaN]	8	hSpCas9	negative selection	10027113
226888838	226888861	1	+	27869803	HPAFII	viability after 31 days	CAAGACCTACAATGTGGCCATGG	PSEN2	ENSG00000143801	0.32654359356850726	[380]	[192,349,NaN]	2	hSpCas9	negative selection	10027114
226890072	226890095	1	+	27869803	HPAFII	viability after 31 days	AATGCTGGTAGAAACTGCCCAGG	PSEN2	ENSG00000143801	-0.44176268373316363	[25]	[4,16,NaN]	-3	hSpCas9	negative selection	10027115
226883704	226883727	1	+	28162770	P31FUJ	viability	GAGAAGCCAGGAGAACGAGGAGG	PSEN2	ENSG00000143801	-0.5611280704998916	[112]	[89]	-5	hSpCas9	negative selection	10218551
226885554	226885577	1	+	28162770	P31FUJ	viability	ACTGAGGACACACCCTCGGTGGG	PSEN2	ENSG00000143801	0.006663730281010743	[215]	[254]	0	hSpCas9	negative selection	10218552
226883874	226883897	1	-	28162770	P31FUJ	viability	GAAGCGCACAGACTTGATGGTGG	PSEN2	ENSG00000143801	0.3213980425360905	[78]	[115]	3	hSpCas9	negative selection	10218553
226882026	226882049	1	+	28162770	P31FUJ	viability	ATGGAGAGAACACTGCCCAGTGG	PSEN2	ENSG00000143801	0.6982504418681299	[149]	[285]	7	hSpCas9	negative selection	10218554
226888867	226888890	1	-	28162770	P31FUJ	viability	CCAGACAGTCAGCAAGAGGGTGG	PSEN2	ENSG00000143801	-0.6895177349430931	[198]	[144]	-5	hSpCas9	negative selection	10218555
226888919	226888942	1	-	28162770	P31FUJ	viability	GCACCAGAGGGCCCTTCCAGTGG	PSEN2	ENSG00000143801	-1.999515141974637	[244]	[71]	-8	hSpCas9	negative selection	10218556
226890072	226890095	1	+	28162770	P31FUJ	viability	AATGCTGGTAGAAACTGCCCAGG	PSEN2	ENSG00000143801	0.6082082718244645	[229]	[411]	7	hSpCas9	negative selection	10218557
226891315	226891338	1	-	28162770	P31FUJ	viability	GGAGGGCACCCTGAGAGGAGGGG	PSEN2	ENSG00000143801	-1.0318895104883823	[260]	[149]	-6	hSpCas9	negative selection	10218558
226883716	226883739	1	+	28162770	P31FUJ	viability	GAACGAGGAGGACGGTGAGGAGG	PSEN2	ENSG00000143801	0.4676375137267139	[15]	[25]	5	hSpCas9	negative selection	10218559
226883746	226883769	1	-	28162770	P31FUJ	viability	GAACCCCACTACAGACATAGCGG	PSEN2	ENSG00000143801	-0.08134986304354522	[261]	[290]	-1	hSpCas9	negative selection	10218560
226883704	226883727	1	+	28162770	TF1	viability	GAGAAGCCAGGAGAACGAGGAGG	PSEN2	ENSG00000143801	NaN	[NaN]	[1]	1	hSpCas9	negative selection	10387917
226885554	226885577	1	+	28162770	TF1	viability	ACTGAGGACACACCCTCGGTGGG	PSEN2	ENSG00000143801	NaN	[NaN]	[228]	1	hSpCas9	negative selection	10387918
226883874	226883897	1	-	28162770	TF1	viability	GAAGCGCACAGACTTGATGGTGG	PSEN2	ENSG00000143801	NaN	[NaN]	[27]	1	hSpCas9	negative selection	10387919
226882026	226882049	1	+	28162770	TF1	viability	ATGGAGAGAACACTGCCCAGTGG	PSEN2	ENSG00000143801	NaN	[NaN]	[87]	1	hSpCas9	negative selection	10387920
226888867	226888890	1	-	28162770	TF1	viability	CCAGACAGTCAGCAAGAGGGTGG	PSEN2	ENSG00000143801	NaN	[NaN]	[66]	1	hSpCas9	negative selection	10387921
226888919	226888942	1	-	28162770	TF1	viability	GCACCAGAGGGCCCTTCCAGTGG	PSEN2	ENSG00000143801	NaN	[NaN]	[9]	1	hSpCas9	negative selection	10387922
226890072	226890095	1	+	28162770	TF1	viability	AATGCTGGTAGAAACTGCCCAGG	PSEN2	ENSG00000143801	NaN	[NaN]	[252]	1	hSpCas9	negative selection	10387923
226891315	226891338	1	-	28162770	TF1	viability	GGAGGGCACCCTGAGAGGAGGGG	PSEN2	ENSG00000143801	NaN	[NaN]	[219]	1	hSpCas9	negative selection	10387924
226883716	226883739	1	+	28162770	TF1	viability	GAACGAGGAGGACGGTGAGGAGG	PSEN2	ENSG00000143801	NaN	[NaN]	[23]	1	hSpCas9	negative selection	10387925
226883746	226883769	1	-	28162770	TF1	viability	GAACCCCACTACAGACATAGCGG	PSEN2	ENSG00000143801	NaN	[NaN]	[221]	1	hSpCas9	negative selection	10387926
226883704	226883727	1	+	28162770	SKM1	viability	GAGAAGCCAGGAGAACGAGGAGG	PSEN2	ENSG00000143801	-1.1268562795504264	[41]	[33]	-7	hSpCas9	negative selection	10557283
226885554	226885577	1	+	28162770	SKM1	viability	ACTGAGGACACACCCTCGGTGGG	PSEN2	ENSG00000143801	0.3943162089047582	[33]	[78]	4	hSpCas9	negative selection	10557284
226883874	226883897	1	-	28162770	SKM1	viability	GAAGCGCACAGACTTGATGGTGG	PSEN2	ENSG00000143801	0.34792330342030686	[23]	[53]	3	hSpCas9	negative selection	10557285
226882026	226882049	1	+	28162770	SKM1	viability	ATGGAGAGAACACTGCCCAGTGG	PSEN2	ENSG00000143801	0.4140656602115189	[44]	[105]	4	hSpCas9	negative selection	10557286
226888867	226888890	1	-	28162770	SKM1	viability	CCAGACAGTCAGCAAGAGGGTGG	PSEN2	ENSG00000143801	-0.3987902672974616	[43]	[58]	-3	hSpCas9	negative selection	10557287
226888919	226888942	1	-	28162770	SKM1	viability	GCACCAGAGGGCCCTTCCAGTGG	PSEN2	ENSG00000143801	-3.332963617299385	[56]	[9]	-9	hSpCas9	negative selection	10557288
226890072	226890095	1	+	28162770	SKM1	viability	AATGCTGGTAGAAACTGCCCAGG	PSEN2	ENSG00000143801	0.6710383132581113	[53]	[151]	6	hSpCas9	negative selection	10557289
226891315	226891338	1	-	28162770	SKM1	viability	GGAGGGCACCCTGAGAGGAGGGG	PSEN2	ENSG00000143801	-2.3663222142458156	[69]	[23]	-8	hSpCas9	negative selection	10557290
226883716	226883739	1	+	28162770	SKM1	viability	GAACGAGGAGGACGGTGAGGAGG	PSEN2	ENSG00000143801	-1.8220016980220048	[1]	[0]	-8	hSpCas9	negative selection	10557291
226883746	226883769	1	-	28162770	SKM1	viability	GAACCCCACTACAGACATAGCGG	PSEN2	ENSG00000143801	-0.44696226667508077	[63]	[82]	-4	hSpCas9	negative selection	10557292
226883704	226883727	1	+	28162770	SKM1	viability	GAGAAGCCAGGAGAACGAGGAGG	PSEN2	ENSG00000143801	-1.1268562795504264	[41]	[33]	-7	hSpCas9	negative selection	10726649
226885554	226885577	1	+	28162770	SKM1	viability	ACTGAGGACACACCCTCGGTGGG	PSEN2	ENSG00000143801	0.3943162089047582	[33]	[78]	4	hSpCas9	negative selection	10726650
226883874	226883897	1	-	28162770	SKM1	viability	GAAGCGCACAGACTTGATGGTGG	PSEN2	ENSG00000143801	0.34792330342030686	[23]	[53]	3	hSpCas9	negative selection	10726651
226882026	226882049	1	+	28162770	SKM1	viability	ATGGAGAGAACACTGCCCAGTGG	PSEN2	ENSG00000143801	0.4140656602115189	[44]	[105]	4	hSpCas9	negative selection	10726652
226888867	226888890	1	-	28162770	SKM1	viability	CCAGACAGTCAGCAAGAGGGTGG	PSEN2	ENSG00000143801	-0.3987902672974616	[43]	[58]	-3	hSpCas9	negative selection	10726653
226888919	226888942	1	-	28162770	SKM1	viability	GCACCAGAGGGCCCTTCCAGTGG	PSEN2	ENSG00000143801	-3.332963617299385	[56]	[9]	-9	hSpCas9	negative selection	10726654
226890072	226890095	1	+	28162770	SKM1	viability	AATGCTGGTAGAAACTGCCCAGG	PSEN2	ENSG00000143801	0.6710383132581113	[53]	[151]	6	hSpCas9	negative selection	10726655
226891315	226891338	1	-	28162770	SKM1	viability	GGAGGGCACCCTGAGAGGAGGGG	PSEN2	ENSG00000143801	-2.3663222142458156	[69]	[23]	-8	hSpCas9	negative selection	10726656
226883716	226883739	1	+	28162770	SKM1	viability	GAACGAGGAGGACGGTGAGGAGG	PSEN2	ENSG00000143801	-1.8220016980220048	[1]	[0]	-8	hSpCas9	negative selection	10726657
226883746	226883769	1	-	28162770	SKM1	viability	GAACCCCACTACAGACATAGCGG	PSEN2	ENSG00000143801	-0.44696226667508077	[63]	[82]	-4	hSpCas9	negative selection	10726658
226883704	226883727	1	+	28162770	PL21	viability	GAGAAGCCAGGAGAACGAGGAGG	PSEN2	ENSG00000143801	-0.259292004147977	[142]	[51]	-2	hSpCas9	negative selection	10896015
226885554	226885577	1	+	28162770	PL21	viability	ACTGAGGACACACCCTCGGTGGG	PSEN2	ENSG00000143801	0.9106329972943351	[109]	[89]	7	hSpCas9	negative selection	10896016
226883874	226883897	1	-	28162770	PL21	viability	GAAGCGCACAGACTTGATGGTGG	PSEN2	ENSG00000143801	1.1006039409384056	[104]	[97]	8	hSpCas9	negative selection	10896017
226882026	226882049	1	+	28162770	PL21	viability	ATGGAGAGAACACTGCCCAGTGG	PSEN2	ENSG00000143801	1.1648065413770394	[247]	[241]	8	hSpCas9	negative selection	10896018
226888867	226888890	1	-	28162770	PL21	viability	CCAGACAGTCAGCAAGAGGGTGG	PSEN2	ENSG00000143801	-1.0510854890548402	[218]	[45]	-6	hSpCas9	negative selection	10896019
226888919	226888942	1	-	28162770	PL21	viability	GCACCAGAGGGCCCTTCCAGTGG	PSEN2	ENSG00000143801	-1.6564962103395027	[267]	[36]	-8	hSpCas9	negative selection	10896020
226890072	226890095	1	+	28162770	PL21	viability	AATGCTGGTAGAAACTGCCCAGG	PSEN2	ENSG00000143801	0.45845161008071084	[203]	[121]	4	hSpCas9	negative selection	10896021
226891315	226891338	1	-	28162770	PL21	viability	GGAGGGCACCCTGAGAGGAGGGG	PSEN2	ENSG00000143801	-1.3294798523880609	[178]	[30]	-7	hSpCas9	negative selection	10896022
226883716	226883739	1	+	28162770	PL21	viability	GAACGAGGAGGACGGTGAGGAGG	PSEN2	ENSG00000143801	-0.9153376029306166	[12]	[2]	-6	hSpCas9	negative selection	10896023
226883746	226883769	1	-	28162770	PL21	viability	GAACCCCACTACAGACATAGCGG	PSEN2	ENSG00000143801	0.6184522458010249	[219]	[146]	5	hSpCas9	negative selection	10896024
226883704	226883727	1	+	28162770	P31FUJ	viability	GAGAAGCCAGGAGAACGAGGAGG	PSEN2	ENSG00000143801	-0.5611280704998916	[112]	[89]	-5	hSpCas9	negative selection	11065381
226885554	226885577	1	+	28162770	P31FUJ	viability	ACTGAGGACACACCCTCGGTGGG	PSEN2	ENSG00000143801	0.006663730281010743	[215]	[254]	0	hSpCas9	negative selection	11065382
226883874	226883897	1	-	28162770	P31FUJ	viability	GAAGCGCACAGACTTGATGGTGG	PSEN2	ENSG00000143801	0.3213980425360905	[78]	[115]	3	hSpCas9	negative selection	11065383
226882026	226882049	1	+	28162770	P31FUJ	viability	ATGGAGAGAACACTGCCCAGTGG	PSEN2	ENSG00000143801	0.6982504418681299	[149]	[285]	7	hSpCas9	negative selection	11065384
226888867	226888890	1	-	28162770	P31FUJ	viability	CCAGACAGTCAGCAAGAGGGTGG	PSEN2	ENSG00000143801	-0.6895177349430931	[198]	[144]	-5	hSpCas9	negative selection	11065385
226888919	226888942	1	-	28162770	P31FUJ	viability	GCACCAGAGGGCCCTTCCAGTGG	PSEN2	ENSG00000143801	-1.999515141974637	[244]	[71]	-8	hSpCas9	negative selection	11065386
226890072	226890095	1	+	28162770	P31FUJ	viability	AATGCTGGTAGAAACTGCCCAGG	PSEN2	ENSG00000143801	0.6082082718244645	[229]	[411]	7	hSpCas9	negative selection	11065387
226891315	226891338	1	-	28162770	P31FUJ	viability	GGAGGGCACCCTGAGAGGAGGGG	PSEN2	ENSG00000143801	-1.0318895104883823	[260]	[149]	-6	hSpCas9	negative selection	11065388
226883716	226883739	1	+	28162770	P31FUJ	viability	GAACGAGGAGGACGGTGAGGAGG	PSEN2	ENSG00000143801	0.4676375137267139	[15]	[25]	5	hSpCas9	negative selection	11065389
226883746	226883769	1	-	28162770	P31FUJ	viability	GAACCCCACTACAGACATAGCGG	PSEN2	ENSG00000143801	-0.08134986304354522	[261]	[290]	-1	hSpCas9	negative selection	11065390
226883704	226883727	1	+	28162770	OCIAML5	viability	GAGAAGCCAGGAGAACGAGGAGG	PSEN2	ENSG00000143801	-0.8362992550056804	[90]	[91]	-5	hSpCas9	negative selection	11234747
226885554	226885577	1	+	28162770	OCIAML5	viability	ACTGAGGACACACCCTCGGTGGG	PSEN2	ENSG00000143801	1.2859743695585295	[121]	[536]	9	hSpCas9	negative selection	11234748
226883874	226883897	1	-	28162770	OCIAML5	viability	GAAGCGCACAGACTTGATGGTGG	PSEN2	ENSG00000143801	-3.0135299935581132	[84]	[18]	-8	hSpCas9	negative selection	11234749
226882026	226882049	1	+	28162770	OCIAML5	viability	ATGGAGAGAACACTGCCCAGTGG	PSEN2	ENSG00000143801	0.9866525221029423	[77]	[278]	8	hSpCas9	negative selection	11234750
226888867	226888890	1	-	28162770	OCIAML5	viability	CCAGACAGTCAGCAAGAGGGTGG	PSEN2	ENSG00000143801	0.30101275914039205	[66]	[148]	2	hSpCas9	negative selection	11234751
226888919	226888942	1	-	28162770	OCIAML5	viability	GCACCAGAGGGCCCTTCCAGTGG	PSEN2	ENSG00000143801	-1.9196298546766315	[152]	[72]	-7	hSpCas9	negative selection	11234752
226890072	226890095	1	+	28162770	OCIAML5	viability	AATGCTGGTAGAAACTGCCCAGG	PSEN2	ENSG00000143801	0.182980376235204	[121]	[249]	1	hSpCas9	negative selection	11234753
226891315	226891338	1	-	28162770	OCIAML5	viability	GGAGGGCACCCTGAGAGGAGGGG	PSEN2	ENSG00000143801	0.02367532617385734	[102]	[188]	0	hSpCas9	negative selection	11234754
226883716	226883739	1	+	28162770	OCIAML5	viability	GAACGAGGAGGACGGTGAGGAGG	PSEN2	ENSG00000143801	-0.8520665708639967	[0]	[0]	-5	hSpCas9	negative selection	11234755
226883746	226883769	1	-	28162770	OCIAML5	viability	GAACCCCACTACAGACATAGCGG	PSEN2	ENSG00000143801	-0.37633313989759926	[191]	[266]	-3	hSpCas9	negative selection	11234756
226883704	226883727	1	+	28162770	EOL1	viability	GAGAAGCCAGGAGAACGAGGAGG	PSEN2	ENSG00000143801	-0.3908571997354934	[330]	[132]	-3	hSpCas9	negative selection	11404113
226885554	226885577	1	+	28162770	EOL1	viability	ACTGAGGACACACCCTCGGTGGG	PSEN2	ENSG00000143801	1.5180217721472082	[168]	[254]	9	hSpCas9	negative selection	11404114
226883874	226883897	1	-	28162770	EOL1	viability	GAAGCGCACAGACTTGATGGTGG	PSEN2	ENSG00000143801	0.1171928495129303	[181]	[103]	1	hSpCas9	negative selection	11404115
226882026	226882049	1	+	28162770	EOL1	viability	ATGGAGAGAACACTGCCCAGTGG	PSEN2	ENSG00000143801	0.11822889626545494	[347]	[198]	1	hSpCas9	negative selection	11404116
226888867	226888890	1	-	28162770	EOL1	viability	CCAGACAGTCAGCAAGAGGGTGG	PSEN2	ENSG00000143801	-0.16006445614440679	[315]	[148]	-1	hSpCas9	negative selection	11404117
226888919	226888942	1	-	28162770	EOL1	viability	GCACCAGAGGGCCCTTCCAGTGG	PSEN2	ENSG00000143801	-1.724831457646392	[457]	[72]	-8	hSpCas9	negative selection	11404118
226890072	226890095	1	+	28162770	EOL1	viability	AATGCTGGTAGAAACTGCCCAGG	PSEN2	ENSG00000143801	0.522651371979757	[254]	[192]	5	hSpCas9	negative selection	11404119
226891315	226891338	1	-	28162770	EOL1	viability	GGAGGGCACCCTGAGAGGAGGGG	PSEN2	ENSG00000143801	0.40371560826909386	[263]	[183]	3	hSpCas9	negative selection	11404120
226883716	226883739	1	+	28162770	EOL1	viability	GAACGAGGAGGACGGTGAGGAGG	PSEN2	ENSG00000143801	-1.8828071504870696	[6]	[0]	-8	hSpCas9	negative selection	11404121
226883746	226883769	1	-	28162770	EOL1	viability	GAACCCCACTACAGACATAGCGG	PSEN2	ENSG00000143801	-0.1749879019803798	[254]	[118]	-1	hSpCas9	negative selection	11404122
226883704	226883727	1	+	28162770	MOLM13	viability	GAGAAGCCAGGAGAACGAGGAGG	PSEN2	ENSG00000143801	-2.241061836452031	[254]	[38]	-7	hSpCas9	negative selection	11573479
226885554	226885577	1	+	28162770	MOLM13	viability	ACTGAGGACACACCCTCGGTGGG	PSEN2	ENSG00000143801	0.4597615006611785	[177]	[176]	3	hSpCas9	negative selection	11573480
226883874	226883897	1	-	28162770	MOLM13	viability	GAAGCGCACAGACTTGATGGTGG	PSEN2	ENSG00000143801	-0.5093905419553377	[125]	[63]	-3	hSpCas9	negative selection	11573481
226882026	226882049	1	+	28162770	MOLM13	viability	ATGGAGAGAACACTGCCCAGTGG	PSEN2	ENSG00000143801	1.19035540601567	[259]	[428]	8	hSpCas9	negative selection	11573482
226888867	226888890	1	-	28162770	MOLM13	viability	CCAGACAGTCAGCAAGAGGGTGG	PSEN2	ENSG00000143801	-0.028635154508993566	[260]	[184]	0	hSpCas9	negative selection	11573483
226888919	226888942	1	-	28162770	MOLM13	viability	GCACCAGAGGGCCCTTCCAGTGG	PSEN2	ENSG00000143801	-3.157945400592105	[357]	[28]	-8	hSpCas9	negative selection	11573484
226890072	226890095	1	+	28162770	MOLM13	viability	AATGCTGGTAGAAACTGCCCAGG	PSEN2	ENSG00000143801	0.32791337211512334	[291]	[264]	2	hSpCas9	negative selection	11573485
226891315	226891338	1	-	28162770	MOLM13	viability	GGAGGGCACCCTGAGAGGAGGGG	PSEN2	ENSG00000143801	-0.8965220446642971	[223]	[86]	-5	hSpCas9	negative selection	11573486
226883716	226883739	1	+	28162770	MOLM13	viability	GAACGAGGAGGACGGTGAGGAGG	PSEN2	ENSG00000143801	-3.232550336596514	[12]	[0]	-8	hSpCas9	negative selection	11573487
226883746	226883769	1	-	28162770	MOLM13	viability	GAACCCCACTACAGACATAGCGG	PSEN2	ENSG00000143801	0.42500356869140243	[477]	[463]	3	hSpCas9	negative selection	11573488
226883704	226883727	1	+	28162770	HEL	viability	GAGAAGCCAGGAGAACGAGGAGG	PSEN2	ENSG00000143801	-0.3391138212893837	[157]	[79]	-2	hSpCas9	negative selection	11742845
226885554	226885577	1	+	28162770	HEL	viability	ACTGAGGACACACCCTCGGTGGG	PSEN2	ENSG00000143801	-0.28944578377207153	[186]	[97]	-2	hSpCas9	negative selection	11742846
226883874	226883897	1	-	28162770	HEL	viability	GAAGCGCACAGACTTGATGGTGG	PSEN2	ENSG00000143801	0.6780719051126377	[120]	[123]	6	hSpCas9	negative selection	11742847
226882026	226882049	1	+	28162770	HEL	viability	ATGGAGAGAACACTGCCCAGTGG	PSEN2	ENSG00000143801	1.3392096479385036	[223]	[362]	9	hSpCas9	negative selection	11742848
226888867	226888890	1	-	28162770	HEL	viability	CCAGACAGTCAGCAAGAGGGTGG	PSEN2	ENSG00000143801	0.06559583573850014	[275]	[184]	0	hSpCas9	negative selection	11742849
226888919	226888942	1	-	28162770	HEL	viability	GCACCAGAGGGCCCTTCCAGTGG	PSEN2	ENSG00000143801	-2.9801915189198196	[307]	[24]	-8	hSpCas9	negative selection	11742850
226890072	226890095	1	+	28162770	HEL	viability	AATGCTGGTAGAAACTGCCCAGG	PSEN2	ENSG00000143801	0.8591325127153617	[240]	[279]	7	hSpCas9	negative selection	11742851
226891315	226891338	1	-	28162770	HEL	viability	GGAGGGCACCCTGAGAGGAGGGG	PSEN2	ENSG00000143801	-0.42203142338988087	[204]	[97]	-3	hSpCas9	negative selection	11742852
226883716	226883739	1	+	28162770	HEL	viability	GAACGAGGAGGACGGTGAGGAGG	PSEN2	ENSG00000143801	-2.942223668720799	[11]	[0]	-8	hSpCas9	negative selection	11742853
226883746	226883769	1	-	28162770	HEL	viability	GAACCCCACTACAGACATAGCGG	PSEN2	ENSG00000143801	-0.21496728553452132	[327]	[180]	-1	hSpCas9	negative selection	11742854
226883704	226883727	1	+	28162770	MV411	viability	GAGAAGCCAGGAGAACGAGGAGG	PSEN2	ENSG00000143801	-0.6165008996411963	[181]	[99]	-4	hSpCas9	negative selection	11912211
226885554	226885577	1	+	28162770	MV411	viability	ACTGAGGACACACCCTCGGTGGG	PSEN2	ENSG00000143801	0.6534299104586121	[159]	[211]	6	hSpCas9	negative selection	11912212
226883874	226883897	1	-	28162770	MV411	viability	GAAGCGCACAGACTTGATGGTGG	PSEN2	ENSG00000143801	0.7949253460852688	[51]	[75]	7	hSpCas9	negative selection	11912213
226882026	226882049	1	+	28162770	MV411	viability	ATGGAGAGAACACTGCCCAGTGG	PSEN2	ENSG00000143801	0.035933445589063584	[219]	[189]	0	hSpCas9	negative selection	11912214
226888867	226888890	1	-	28162770	MV411	viability	CCAGACAGTCAGCAAGAGGGTGG	PSEN2	ENSG00000143801	-2.25240833630043	[180]	[31]	-8	hSpCas9	negative selection	11912215
226888919	226888942	1	-	28162770	MV411	viability	GCACCAGAGGGCCCTTCCAGTGG	PSEN2	ENSG00000143801	-2.532540932343524	[260]	[37]	-8	hSpCas9	negative selection	11912216
226890072	226890095	1	+	28162770	MV411	viability	AATGCTGGTAGAAACTGCCCAGG	PSEN2	ENSG00000143801	0.6566459712594215	[185]	[246]	6	hSpCas9	negative selection	11912217
226891315	226891338	1	-	28162770	MV411	viability	GGAGGGCACCCTGAGAGGAGGGG	PSEN2	ENSG00000143801	0.5330586416838095	[168]	[205]	5	hSpCas9	negative selection	11912218
226883716	226883739	1	+	28162770	MV411	viability	GAACGAGGAGGACGGTGAGGAGG	PSEN2	ENSG00000143801	-0.974954870553673	[6]	[2]	-6	hSpCas9	negative selection	11912219
226883746	226883769	1	-	28162770	MV411	viability	GAACCCCACTACAGACATAGCGG	PSEN2	ENSG00000143801	0.6227749262413615	[174]	[226]	5	hSpCas9	negative selection	11912220
226883704	226883727	1	+	28162770	MONOMAC1	viability	GAGAAGCCAGGAGAACGAGGAGG	PSEN2	ENSG00000143801	0.1164626257572279	[102]	[127]	1	hSpCas9	negative selection	12081577
226885554	226885577	1	+	28162770	MONOMAC1	viability	ACTGAGGACACACCCTCGGTGGG	PSEN2	ENSG00000143801	-0.6219221322947448	[97]	[72]	-5	hSpCas9	negative selection	12081578
226883874	226883897	1	-	28162770	MONOMAC1	viability	GAAGCGCACAGACTTGATGGTGG	PSEN2	ENSG00000143801	0.014467258134158056	[56]	[65]	0	hSpCas9	negative selection	12081579
226882026	226882049	1	+	28162770	MONOMAC1	viability	ATGGAGAGAACACTGCCCAGTGG	PSEN2	ENSG00000143801	0.31850425270412297	[148]	[212]	3	hSpCas9	negative selection	12081580
226888867	226888890	1	-	28162770	MONOMAC1	viability	CCAGACAGTCAGCAAGAGGGTGG	PSEN2	ENSG00000143801	-0.1970368470595539	[124]	[124]	-2	hSpCas9	negative selection	12081581
226888919	226888942	1	-	28162770	MONOMAC1	viability	GCACCAGAGGGCCCTTCCAGTGG	PSEN2	ENSG00000143801	-1.3715345782916903	[157]	[69]	-8	hSpCas9	negative selection	12081582
226890072	226890095	1	+	28162770	MONOMAC1	viability	AATGCTGGTAGAAACTGCCCAGG	PSEN2	ENSG00000143801	0.6134853540767334	[129]	[227]	6	hSpCas9	negative selection	12081583
226891315	226891338	1	-	28162770	MONOMAC1	viability	GGAGGGCACCCTGAGAGGAGGGG	PSEN2	ENSG00000143801	-0.4627704024943027	[106]	[88]	-4	hSpCas9	negative selection	12081584
226883716	226883739	1	+	28162770	MONOMAC1	viability	GAACGAGGAGGACGGTGAGGAGG	PSEN2	ENSG00000143801	-1.1970368470595538	[1]	[0]	-7	hSpCas9	negative selection	12081585
226883746	226883769	1	-	28162770	MONOMAC1	viability	GAACCCCACTACAGACATAGCGG	PSEN2	ENSG00000143801	1.172608749405276	[112]	[291]	8	hSpCas9	negative selection	12081586
226883704	226883727	1	+	28162770	OCIAML2	viability	GAGAAGCCAGGAGAACGAGGAGG	PSEN2	ENSG00000143801	-1.6108074832904216	[26]	[48]	-7	hSpCas9	negative selection	12250943
226885554	226885577	1	+	28162770	OCIAML2	viability	ACTGAGGACACACCCTCGGTGGG	PSEN2	ENSG00000143801	0.5246166447872043	[37]	[302]	5	hSpCas9	negative selection	12250944
226883874	226883897	1	-	28162770	OCIAML2	viability	GAAGCGCACAGACTTGATGGTGG	PSEN2	ENSG00000143801	0.5737642941162922	[7]	[65]	5	hSpCas9	negative selection	12250945
226882026	226882049	1	+	28162770	OCIAML2	viability	ATGGAGAGAACACTGCCCAGTGG	PSEN2	ENSG00000143801	0.2584736511510745	[45]	[304]	2	hSpCas9	negative selection	12250946
226888867	226888890	1	-	28162770	OCIAML2	viability	CCAGACAGTCAGCAAGAGGGTGG	PSEN2	ENSG00000143801	-0.9274875002156321	[34]	[101]	-6	hSpCas9	negative selection	12250947
226888919	226888942	1	-	28162770	OCIAML2	viability	GCACCAGAGGGCCCTTCCAGTGG	PSEN2	ENSG00000143801	-2.541019153133559	[41]	[39]	-8	hSpCas9	negative selection	12250948
226890072	226890095	1	+	28162770	OCIAML2	viability	AATGCTGGTAGAAACTGCCCAGG	PSEN2	ENSG00000143801	-0.39848003948632593	[38]	[163]	-3	hSpCas9	negative selection	12250949
226891315	226891338	1	-	28162770	OCIAML2	viability	GGAGGGCACCCTGAGAGGAGGGG	PSEN2	ENSG00000143801	-1.3402331879864862	[36]	[80]	-7	hSpCas9	negative selection	12250950
226883716	226883739	1	+	28162770	OCIAML2	viability	GAACGAGGAGGACGGTGAGGAGG	PSEN2	ENSG00000143801	0.33672509681544227	[0]	[6]	3	hSpCas9	negative selection	12250951
226883746	226883769	1	-	28162770	OCIAML2	viability	GAACCCCACTACAGACATAGCGG	PSEN2	ENSG00000143801	0.5682891640501413	[31]	[262]	5	hSpCas9	negative selection	12250952
226883704	226883727	1	+	28162770	OCIAML3	viability	GAGAAGCCAGGAGAACGAGGAGG	PSEN2	ENSG00000143801	-0.5820349986580872	[59]	[120]	-4	hSpCas9	negative selection	12420309
226885554	226885577	1	+	28162770	OCIAML3	viability	ACTGAGGACACACCCTCGGTGGG	PSEN2	ENSG00000143801	-0.4402023042451278	[39]	[88]	-3	hSpCas9	negative selection	12420310
226883874	226883897	1	-	28162770	OCIAML3	viability	GAAGCGCACAGACTTGATGGTGG	PSEN2	ENSG00000143801	-1.825333186430619	[26]	[22]	-8	hSpCas9	negative selection	12420311
226882026	226882049	1	+	28162770	OCIAML3	viability	ATGGAGAGAACACTGCCCAGTGG	PSEN2	ENSG00000143801	1.099014606254446	[29]	[193]	8	hSpCas9	negative selection	12420312
226888867	226888890	1	-	28162770	OCIAML3	viability	CCAGACAGTCAGCAAGAGGGTGG	PSEN2	ENSG00000143801	-0.3681262329078353	[58]	[137]	-3	hSpCas9	negative selection	12420313
226888919	226888942	1	-	28162770	OCIAML3	viability	GCACCAGAGGGCCCTTCCAGTGG	PSEN2	ENSG00000143801	-1.9830499310700624	[54]	[41]	-8	hSpCas9	negative selection	12420314
226890072	226890095	1	+	28162770	OCIAML3	viability	AATGCTGGTAGAAACTGCCCAGG	PSEN2	ENSG00000143801	0.5612705851537478	[65]	[293]	5	hSpCas9	negative selection	12420315
226891315	226891338	1	-	28162770	OCIAML3	viability	GGAGGGCACCCTGAGAGGAGGGG	PSEN2	ENSG00000143801	-1.165913988219873	[54]	[73]	-7	hSpCas9	negative selection	12420316
226883716	226883739	1	+	28162770	OCIAML3	viability	GAACGAGGAGGACGGTGAGGAGG	PSEN2	ENSG00000143801	-2.4013625623817676	[6]	[3]	-9	hSpCas9	negative selection	12420317
226883746	226883769	1	-	28162770	OCIAML3	viability	GAACCCCACTACAGACATAGCGG	PSEN2	ENSG00000143801	-0.746010733769213	[59]	[107]	-5	hSpCas9	negative selection	12420318