Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:5732
• Symbol:PTGER2
• Description:prostaglandin E receptor 2

DataSource: http://genomecrispr.dkfz.de/#!/results/PTGER2

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
52315301	52315324	14	+	26472758	Jiyoye	viability	GGAAAGGGTGTCCATGGCGGAGG	PTGER2	ENSG00000125384	0.24671070931262706	[18]	[16]	2	hSpCas9	negative selection	130638
52314824	52314847	14	+	26472758	Jiyoye	viability	GTACGCGCGGAACCAGACCCTGG	PTGER2	ENSG00000125384	-0.37370732919053967	[188]	[109]	-3	hSpCas9	negative selection	130639
52314737	52314760	14	-	26472758	Jiyoye	viability	CCAGCACGTGGAACAAGGAGAGG	PTGER2	ENSG00000125384	2.071991189916244	[40]	[129]	8	hSpCas9	negative selection	130640
52315105	52315128	14	+	26472758	Jiyoye	viability	GGTGCTTCATCCGGCACGGGCGG	PTGER2	ENSG00000125384	-0.46072108248678156	[145]	[79]	-3	hSpCas9	negative selection	130641
52315150	52315173	14	-	26472758	Jiyoye	viability	AATGAGAAGCAGCAGCAGGGTGG	PTGER2	ENSG00000125384	0.5446789052558083	[99]	[109]	4	hSpCas9	negative selection	130642
52315331	52315354	14	-	26472758	Jiyoye	viability	TGATAGCCAGGAGAATGAGGTGG	PTGER2	ENSG00000125384	0.2003443973201664	[291]	[252]	1	hSpCas9	negative selection	130643
52314580	52314603	14	+	26472758	Jiyoye	viability	AGGACTGCGAGACGCGACAGTGG	PTGER2	ENSG00000125384	-0.5497558966022408	[65]	[33]	-4	hSpCas9	negative selection	130644
52314656	52314679	14	+	26472758	Jiyoye	viability	GCTGGGGAACCTCATAGCACTGG	PTGER2	ENSG00000125384	1.7291034763932356	[21]	[54]	8	hSpCas9	negative selection	130645
52314749	52314772	14	-	26472758	Jiyoye	viability	CCAGCTCGGTCACCAGCACGTGG	PTGER2	ENSG00000125384	-0.49189570964334584	[68]	[36]	-4	hSpCas9	negative selection	130646
52314791	52314814	14	+	26472758	Jiyoye	viability	GACCTGCCTCATCAGCCCAGTGG	PTGER2	ENSG00000125384	0.8242264122223657	[178]	[238]	6	hSpCas9	negative selection	130647
52315301	52315324	14	+	26472758	KBM7	viability	GGAAAGGGTGTCCATGGCGGAGG	PTGER2	ENSG00000125384	-0.4141071909028291	[127,42]	[13,41]	-4	hSpCas9	negative selection	321756
52314824	52314847	14	+	26472758	KBM7	viability	GTACGCGCGGAACCAGACCCTGG	PTGER2	ENSG00000125384	-0.5267711857602164	[682,626]	[187,236]	-5	hSpCas9	negative selection	321757
52314737	52314760	14	-	26472758	KBM7	viability	CCAGCACGTGGAACAAGGAGAGG	PTGER2	ENSG00000125384	0.8170244880898013	[696,691]	[598,558]	8	hSpCas9	negative selection	321758
52315105	52315128	14	+	26472758	KBM7	viability	GGTGCTTCATCCGGCACGGGCGG	PTGER2	ENSG00000125384	0.5669107372050637	[410,307]	[248,246]	6	hSpCas9	negative selection	321759
52315150	52315173	14	-	26472758	KBM7	viability	AATGAGAAGCAGCAGCAGGGTGG	PTGER2	ENSG00000125384	0.7664256203719637	[435,309]	[329,262]	8	hSpCas9	negative selection	321760
52315331	52315354	14	-	26472758	KBM7	viability	TGATAGCCAGGAGAATGAGGTGG	PTGER2	ENSG00000125384	0.2765116703261492	[1412,1074]	[860,559]	3	hSpCas9	negative selection	321761
52314580	52314603	14	+	26472758	KBM7	viability	AGGACTGCGAGACGCGACAGTGG	PTGER2	ENSG00000125384	0.16935808857106205	[328,260]	[118,186]	1	hSpCas9	negative selection	321762
52314656	52314679	14	+	26472758	KBM7	viability	GCTGGGGAACCTCATAGCACTGG	PTGER2	ENSG00000125384	0.28243520874479117	[404,302]	[210,190]	3	hSpCas9	negative selection	321763
52314749	52314772	14	-	26472758	KBM7	viability	CCAGCTCGGTCACCAGCACGTGG	PTGER2	ENSG00000125384	0.28335852071580925	[186,232]	[157,89]	3	hSpCas9	negative selection	321764
52314791	52314814	14	+	26472758	KBM7	viability	GACCTGCCTCATCAGCCCAGTGG	PTGER2	ENSG00000125384	0.6582345864077574	[1310,1309]	[1125,843]	7	hSpCas9	negative selection	321765
52315301	52315324	14	+	26472758	Raji	viability	GGAAAGGGTGTCCATGGCGGAGG	PTGER2	ENSG00000125384	-2.477578965347557	[47]	[1]	-9	hSpCas9	negative selection	512874
52314824	52314847	14	+	26472758	Raji	viability	GTACGCGCGGAACCAGACCCTGG	PTGER2	ENSG00000125384	-0.1614833157623491	[346]	[71]	-1	hSpCas9	negative selection	512875
52314737	52314760	14	-	26472758	Raji	viability	CCAGCACGTGGAACAAGGAGAGG	PTGER2	ENSG00000125384	1.2765696404920064	[216]	[121]	9	hSpCas9	negative selection	512876
52315105	52315128	14	+	26472758	Raji	viability	GGTGCTTCATCCGGCACGGGCGG	PTGER2	ENSG00000125384	-0.39246235170960597	[180]	[31]	-3	hSpCas9	negative selection	512877
52315150	52315173	14	-	26472758	Raji	viability	AATGAGAAGCAGCAGCAGGGTGG	PTGER2	ENSG00000125384	0.24545967077657213	[228]	[62]	2	hSpCas9	negative selection	512878
52315331	52315354	14	-	26472758	Raji	viability	TGATAGCCAGGAGAATGAGGTGG	PTGER2	ENSG00000125384	0.09567011480980903	[370]	[91]	0	hSpCas9	negative selection	512879
52314580	52314603	14	+	26472758	Raji	viability	AGGACTGCGAGACGCGACAGTGG	PTGER2	ENSG00000125384	-0.2676558959733253	[82]	[15]	-2	hSpCas9	negative selection	512880
52314656	52314679	14	+	26472758	Raji	viability	GCTGGGGAACCTCATAGCACTGG	PTGER2	ENSG00000125384	0.0355928523055892	[205]	[48]	0	hSpCas9	negative selection	512881
52314749	52314772	14	-	26472758	Raji	viability	CCAGCTCGGTCACCAGCACGTGG	PTGER2	ENSG00000125384	0.0030468755588637375	[85]	[19]	0	hSpCas9	negative selection	512882
52314791	52314814	14	+	26472758	Raji	viability	GACCTGCCTCATCAGCCCAGTGG	PTGER2	ENSG00000125384	-0.07040358384168321	[551]	[121]	0	hSpCas9	negative selection	512883
52315301	52315324	14	+	26472758	K562	viability	GGAAAGGGTGTCCATGGCGGAGG	PTGER2	ENSG00000125384	0.9372372181482709	[72]	[117]	7	hSpCas9	negative selection	703992
52314824	52314847	14	+	26472758	K562	viability	GTACGCGCGGAACCAGACCCTGG	PTGER2	ENSG00000125384	-0.010395171362378455	[419]	[351]	0	hSpCas9	negative selection	703993
52314737	52314760	14	-	26472758	K562	viability	CCAGCACGTGGAACAAGGAGAGG	PTGER2	ENSG00000125384	0.1532708396082516	[636]	[597]	1	hSpCas9	negative selection	703994
52315105	52315128	14	+	26472758	K562	viability	GGTGCTTCATCCGGCACGGGCGG	PTGER2	ENSG00000125384	-0.8226954681920899	[439]	[209]	-5	hSpCas9	negative selection	703995
52315150	52315173	14	-	26472758	K562	viability	AATGAGAAGCAGCAGCAGGGTGG	PTGER2	ENSG00000125384	-0.6887941811223507	[400]	[209]	-4	hSpCas9	negative selection	703996
52315331	52315354	14	-	26472758	K562	viability	TGATAGCCAGGAGAATGAGGTGG	PTGER2	ENSG00000125384	0.796309406781954	[705]	[1034]	6	hSpCas9	negative selection	703997
52314580	52314603	14	+	26472758	K562	viability	AGGACTGCGAGACGCGACAGTGG	PTGER2	ENSG00000125384	1.1891113559873498	[225]	[434]	8	hSpCas9	negative selection	703998
52314656	52314679	14	+	26472758	K562	viability	GCTGGGGAACCTCATAGCACTGG	PTGER2	ENSG00000125384	0.5728405846393094	[265]	[333]	4	hSpCas9	negative selection	703999
52314749	52314772	14	-	26472758	K562	viability	CCAGCTCGGTCACCAGCACGTGG	PTGER2	ENSG00000125384	-0.8266007356535707	[228]	[108]	-5	hSpCas9	negative selection	704000
52314791	52314814	14	+	26472758	K562	viability	GACCTGCCTCATCAGCCCAGTGG	PTGER2	ENSG00000125384	0.27946567476564754	[731]	[749]	2	hSpCas9	negative selection	704001
52314572	52314595	14	-	26627737	DLD1	viability	GCGTCTCGCAGTCCTCAGACTGG	PTGER2	ENSG00000125384	0.3905579121037588	[315]	[123,194,79]	4	hSpCas9	negative selection	788719
52314742	52314765	14	-	26627737	DLD1	viability	GGTCACCAGCACGTGGAACAAGG	PTGER2	ENSG00000125384	-0.054200649703385784	[693]	[251,164,207]	0	hSpCas9	negative selection	788720
52315105	52315128	14	+	26627737	DLD1	viability	GGTGCTTCATCCGGCACGGGCGG	PTGER2	ENSG00000125384	0.3370258123307357	[103]	[12,20,81]	3	hSpCas9	negative selection	788721
52315216	52315239	14	+	26627737	DLD1	viability	TCCGCATGCACCGCCGAAGCCGG	PTGER2	ENSG00000125384	0.006081483357163853	[1274]	[437,267,476]	0	hSpCas9	negative selection	788722
52327235	52327258	14	+	26627737	DLD1	viability	GAATGAAACCTCTTCCCGAAAGG	PTGER2	ENSG00000125384	1.0115046514877215	[218]	[143,138,131]	8	hSpCas9	negative selection	788723
52327338	52327361	14	-	26627737	DLD1	viability	GAACGCATTAGTCTCAGAACAGG	PTGER2	ENSG00000125384	0.47781996147991024	[423]	[232,229,104]	5	hSpCas9	negative selection	788724
52314572	52314595	14	-	26627737	GBM cells	viability after 5 days	GCGTCTCGCAGTCCTCAGACTGG	PTGER2	ENSG00000125384	0.33918866566355216	[254]	[159,185]	5	hSpCas9	negative selection	871034
52314742	52314765	14	-	26627737	GBM cells	viability after 5 days	GGTCACCAGCACGTGGAACAAGG	PTGER2	ENSG00000125384	0.2464677774485426	[278]	[181,172]	4	hSpCas9	negative selection	871035
52315105	52315128	14	+	26627737	GBM cells	viability after 5 days	GGTGCTTCATCCGGCACGGGCGG	PTGER2	ENSG00000125384	-0.34435727612667844	[57]	[31,16]	-5	hSpCas9	negative selection	871036
52315216	52315239	14	+	26627737	GBM cells	viability after 5 days	TCCGCATGCACCGCCGAAGCCGG	PTGER2	ENSG00000125384	0.09885144539443758	[665]	[349,414]	1	hSpCas9	negative selection	871037
52327235	52327258	14	+	26627737	GBM cells	viability after 5 days	GAATGAAACCTCTTCCCGAAAGG	PTGER2	ENSG00000125384	0.28062319809846503	[207]	[141,128]	4	hSpCas9	negative selection	871038
52327338	52327361	14	-	26627737	GBM cells	viability after 5 days	GAACGCATTAGTCTCAGAACAGG	PTGER2	ENSG00000125384	0.07282658480416673	[280]	[129,186]	1	hSpCas9	negative selection	871039
52314572	52314595	14	-	26627737	GBM cells	viability after 13 days	GCGTCTCGCAGTCCTCAGACTGG	PTGER2	ENSG00000125384	0.4473517150819867	[254]	[261,128]	5	hSpCas9	negative selection	953349
52314742	52314765	14	-	26627737	GBM cells	viability after 13 days	GGTCACCAGCACGTGGAACAAGG	PTGER2	ENSG00000125384	0.2407897684759276	[278]	[206,155]	3	hSpCas9	negative selection	953350
52315105	52315128	14	+	26627737	GBM cells	viability after 13 days	GGTGCTTCATCCGGCACGGGCGG	PTGER2	ENSG00000125384	0.3749313433253665	[57]	[74,12]	5	hSpCas9	negative selection	953351
52315216	52315239	14	+	26627737	GBM cells	viability after 13 days	TCCGCATGCACCGCCGAAGCCGG	PTGER2	ENSG00000125384	-0.30248218456999654	[665]	[308,279]	-4	hSpCas9	negative selection	953352
52327235	52327258	14	+	26627737	GBM cells	viability after 13 days	GAATGAAACCTCTTCCCGAAAGG	PTGER2	ENSG00000125384	0.44831217264784795	[207]	[196,118]	5	hSpCas9	negative selection	953353
52327338	52327361	14	-	26627737	GBM cells	viability after 13 days	GAACGCATTAGTCTCAGAACAGG	PTGER2	ENSG00000125384	0.17911295488449638	[280]	[165,177]	2	hSpCas9	negative selection	953354
52314572	52314595	14	-	26627737	GBM cells	viability after 21 days	GCGTCTCGCAGTCCTCAGACTGG	PTGER2	ENSG00000125384	0.8912548970692385	[254]	[257,255]	8	hSpCas9	negative selection	1035664
52314742	52314765	14	-	26627737	GBM cells	viability after 21 days	GGTCACCAGCACGTGGAACAAGG	PTGER2	ENSG00000125384	0.14842941056523118	[278]	[167,167]	1	hSpCas9	negative selection	1035665
52315105	52315128	14	+	26627737	GBM cells	viability after 21 days	GGTGCTTCATCCGGCACGGGCGG	PTGER2	ENSG00000125384	-1.5359101368893548	[57]	[13,7]	-8	hSpCas9	negative selection	1035666
52315216	52315239	14	+	26627737	GBM cells	viability after 21 days	TCCGCATGCACCGCCGAAGCCGG	PTGER2	ENSG00000125384	0.17908337159532994	[665]	[417,401]	2	hSpCas9	negative selection	1035667
52327235	52327258	14	+	26627737	GBM cells	viability after 21 days	GAATGAAACCTCTTCCCGAAAGG	PTGER2	ENSG00000125384	0.5184556921217296	[207]	[164,158]	5	hSpCas9	negative selection	1035668
52327338	52327361	14	-	26627737	GBM cells	viability after 21 days	GAACGCATTAGTCTCAGAACAGG	PTGER2	ENSG00000125384	0.5639275342291337	[280]	[244,207]	6	hSpCas9	negative selection	1035669
52314572	52314595	14	-	26627737	RPE1	viability after 9 days	GCGTCTCGCAGTCCTCAGACTGG	PTGER2	ENSG00000125384	3.28852317289737	[140]	[436,423]	9	hSpCas9	negative selection	1117979
52314742	52314765	14	-	26627737	RPE1	viability after 9 days	GGTCACCAGCACGTGGAACAAGG	PTGER2	ENSG00000125384	-1.140839455238071	[2142]	[274,341]	-7	hSpCas9	negative selection	1117980
52315105	52315128	14	+	26627737	RPE1	viability after 9 days	GGTGCTTCATCCGGCACGGGCGG	PTGER2	ENSG00000125384	0.4628725733546992	[120]	[32,76]	3	hSpCas9	negative selection	1117981
52315216	52315239	14	+	26627737	RPE1	viability after 9 days	TCCGCATGCACCGCCGAAGCCGG	PTGER2	ENSG00000125384	0.2292884317536339	[1847]	[689,662]	1	hSpCas9	negative selection	1117982
52327235	52327258	14	+	26627737	RPE1	viability after 9 days	GAATGAAACCTCTTCCCGAAAGG	PTGER2	ENSG00000125384	0.024265483722849958	[809]	[263,249]	0	hSpCas9	negative selection	1117983
52327338	52327361	14	-	26627737	RPE1	viability after 9 days	GAACGCATTAGTCTCAGAACAGG	PTGER2	ENSG00000125384	-0.5788588187374404	[1281]	[214,337]	-4	hSpCas9	negative selection	1117984
52314572	52314595	14	-	26627737	RPE1	viability after 12 days	GCGTCTCGCAGTCCTCAGACTGG	PTGER2	ENSG00000125384	3.080290396795692	[140]	[418,215]	9	hSpCas9	negative selection	1200294
52314742	52314765	14	-	26627737	RPE1	viability after 12 days	GGTCACCAGCACGTGGAACAAGG	PTGER2	ENSG00000125384	-1.1191451138188082	[2142]	[232,298]	-6	hSpCas9	negative selection	1200295
52315105	52315128	14	+	26627737	RPE1	viability after 12 days	GGTGCTTCATCCGGCACGGGCGG	PTGER2	ENSG00000125384	1.3373113981726767	[120]	[86,76]	7	hSpCas9	negative selection	1200296
52315216	52315239	14	+	26627737	RPE1	viability after 12 days	TCCGCATGCACCGCCGAAGCCGG	PTGER2	ENSG00000125384	0.2956756985400477	[1847]	[844,359]	2	hSpCas9	negative selection	1200297
52327235	52327258	14	+	26627737	RPE1	viability after 12 days	GAATGAAACCTCTTCCCGAAAGG	PTGER2	ENSG00000125384	-0.20560685690962582	[809]	[161,216]	-1	hSpCas9	negative selection	1200298
52327338	52327361	14	-	26627737	RPE1	viability after 12 days	GAACGCATTAGTCTCAGAACAGG	PTGER2	ENSG00000125384	-0.18516725540421874	[1281]	[283,322]	-1	hSpCas9	negative selection	1200299
52314572	52314595	14	-	26627737	RPE1	viability after 15 days	GCGTCTCGCAGTCCTCAGACTGG	PTGER2	ENSG00000125384	2.9640908441680573	[140]	[381,242]	9	hSpCas9	negative selection	1282609
52314742	52314765	14	-	26627737	RPE1	viability after 15 days	GGTCACCAGCACGTGGAACAAGG	PTGER2	ENSG00000125384	-1.688974242166534	[2142]	[130,242]	-8	hSpCas9	negative selection	1282610
52315105	52315128	14	+	26627737	RPE1	viability after 15 days	GGTGCTTCATCCGGCACGGGCGG	PTGER2	ENSG00000125384	0.8115159912841685	[120]	[55,63]	5	hSpCas9	negative selection	1282611
52315216	52315239	14	+	26627737	RPE1	viability after 15 days	TCCGCATGCACCGCCGAAGCCGG	PTGER2	ENSG00000125384	0.7246795408637692	[1847]	[1123,612]	4	hSpCas9	negative selection	1282612
52327235	52327258	14	+	26627737	RPE1	viability after 15 days	GAATGAAACCTCTTCCCGAAAGG	PTGER2	ENSG00000125384	-0.1574794408775912	[809]	[208,201]	-1	hSpCas9	negative selection	1282613
52327338	52327361	14	-	26627737	RPE1	viability after 15 days	GAACGCATTAGTCTCAGAACAGG	PTGER2	ENSG00000125384	-0.49947668663866374	[1281]	[226,284]	-3	hSpCas9	negative selection	1282614
52314572	52314595	14	-	26627737	RPE1	viability after 18 days	GCGTCTCGCAGTCCTCAGACTGG	PTGER2	ENSG00000125384	3.212808153941278	[140]	[375,327]	9	hSpCas9	negative selection	1364924
52314742	52314765	14	-	26627737	RPE1	viability after 18 days	GGTCACCAGCACGTGGAACAAGG	PTGER2	ENSG00000125384	-1.2376036995559772	[2142]	[208,283]	-6	hSpCas9	negative selection	1364925
52315105	52315128	14	+	26627737	RPE1	viability after 18 days	GGTGCTTCATCCGGCACGGGCGG	PTGER2	ENSG00000125384	0.3977056761791533	[120]	[28,57]	2	hSpCas9	negative selection	1364926
52315216	52315239	14	+	26627737	RPE1	viability after 18 days	TCCGCATGCACCGCCGAAGCCGG	PTGER2	ENSG00000125384	0.6603354229893643	[1847]	[895,672]	4	hSpCas9	negative selection	1364927
52327235	52327258	14	+	26627737	RPE1	viability after 18 days	GAATGAAACCTCTTCCCGAAAGG	PTGER2	ENSG00000125384	-0.41155915867842424	[809]	[115,215]	-3	hSpCas9	negative selection	1364928
52327338	52327361	14	-	26627737	RPE1	viability after 18 days	GAACGCATTAGTCTCAGAACAGG	PTGER2	ENSG00000125384	-0.19343844411547573	[1281]	[347,253]	-1	hSpCas9	negative selection	1364929
52314572	52314595	14	-	26627737	HeLa	viability after 8 days	GCGTCTCGCAGTCCTCAGACTGG	PTGER2	ENSG00000125384	0.01644128466446862	[465]	[282,211,141]	0	hSpCas9	negative selection	1447239
52314742	52314765	14	-	26627737	HeLa	viability after 8 days	GGTCACCAGCACGTGGAACAAGG	PTGER2	ENSG00000125384	-0.09416132995888282	[491]	[214,146,239]	-1	hSpCas9	negative selection	1447240
52315105	52315128	14	+	26627737	HeLa	viability after 8 days	GGTGCTTCATCCGGCACGGGCGG	PTGER2	ENSG00000125384	0.8056611381951331	[72]	[103,28,44]	6	hSpCas9	negative selection	1447241
52315216	52315239	14	+	26627737	HeLa	viability after 8 days	TCCGCATGCACCGCCGAAGCCGG	PTGER2	ENSG00000125384	1.0833548202894292	[669]	[469,869,489]	8	hSpCas9	negative selection	1447242
52327235	52327258	14	+	26627737	HeLa	viability after 8 days	GAATGAAACCTCTTCCCGAAAGG	PTGER2	ENSG00000125384	0.9548898076310581	[161]	[129,208,73]	7	hSpCas9	negative selection	1447243
52327338	52327361	14	-	26627737	HeLa	viability after 8 days	GAACGCATTAGTCTCAGAACAGG	PTGER2	ENSG00000125384	0.05207352745264454	[445]	[234,188,187]	0	hSpCas9	negative selection	1447244
52314572	52314595	14	-	26627737	HeLa	viability after 12 days	GCGTCTCGCAGTCCTCAGACTGG	PTGER2	ENSG00000125384	0.3296254090069968	[465]	[110,281,324]	3	hSpCas9	negative selection	1529554
52314742	52314765	14	-	26627737	HeLa	viability after 12 days	GGTCACCAGCACGTGGAACAAGG	PTGER2	ENSG00000125384	-0.6323907722459094	[491]	[33,146,207]	-5	hSpCas9	negative selection	1529555
52315105	52315128	14	+	26627737	HeLa	viability after 12 days	GGTGCTTCATCCGGCACGGGCGG	PTGER2	ENSG00000125384	0.8811816757641322	[72]	[43,58,62]	6	hSpCas9	negative selection	1529556
52315216	52315239	14	+	26627737	HeLa	viability after 12 days	TCCGCATGCACCGCCGAAGCCGG	PTGER2	ENSG00000125384	0.8202920950784841	[669]	[364,395,711]	6	hSpCas9	negative selection	1529557
52327235	52327258	14	+	26627737	HeLa	viability after 12 days	GAATGAAACCTCTTCCCGAAAGG	PTGER2	ENSG00000125384	0.9141523525716687	[161]	[77,126,171]	7	hSpCas9	negative selection	1529558
52327338	52327361	14	-	26627737	HeLa	viability after 12 days	GAACGCATTAGTCTCAGAACAGG	PTGER2	ENSG00000125384	0.17558142790485964	[445]	[332,133,168]	1	hSpCas9	negative selection	1529559
52314572	52314595	14	-	26627737	HeLa	viability after 15 days	GCGTCTCGCAGTCCTCAGACTGG	PTGER2	ENSG00000125384	-0.15571703897872868	[465]	[163,103,248]	-1	hSpCas9	negative selection	1611869
52314742	52314765	14	-	26627737	HeLa	viability after 15 days	GGTCACCAGCACGTGGAACAAGG	PTGER2	ENSG00000125384	-0.13942434026502462	[491]	[135,108,310]	-1	hSpCas9	negative selection	1611870
52315105	52315128	14	+	26627737	HeLa	viability after 15 days	GGTGCTTCATCCGGCACGGGCGG	PTGER2	ENSG00000125384	0.6853624850670108	[72]	[70,0,72]	5	hSpCas9	negative selection	1611871
52315216	52315239	14	+	26627737	HeLa	viability after 15 days	TCCGCATGCACCGCCGAAGCCGG	PTGER2	ENSG00000125384	1.3106574190878861	[669]	[682,605,745]	8	hSpCas9	negative selection	1611872
52327235	52327258	14	+	26627737	HeLa	viability after 15 days	GAATGAAACCTCTTCCCGAAAGG	PTGER2	ENSG00000125384	0.49208186267139264	[161]	[36,124,118]	4	hSpCas9	negative selection	1611873
52327338	52327361	14	-	26627737	HeLa	viability after 15 days	GAACGCATTAGTCTCAGAACAGG	PTGER2	ENSG00000125384	-0.31707947937122793	[445]	[217,51,167]	-3	hSpCas9	negative selection	1611874
52314572	52314595	14	-	26627737	HeLa	viability after 18 days	GCGTCTCGCAGTCCTCAGACTGG	PTGER2	ENSG00000125384	-0.16064867795808463	[465]	[104,90,248]	-1	hSpCas9	negative selection	1694184
52314742	52314765	14	-	26627737	HeLa	viability after 18 days	GGTCACCAGCACGTGGAACAAGG	PTGER2	ENSG00000125384	-0.08442612058106899	[491]	[101,93,310]	0	hSpCas9	negative selection	1694185
52315105	52315128	14	+	26627737	HeLa	viability after 18 days	GGTGCTTCATCCGGCACGGGCGG	PTGER2	ENSG00000125384	0.6775641420578524	[72]	[46,0,72]	5	hSpCas9	negative selection	1694186
52315216	52315239	14	+	26627737	HeLa	viability after 18 days	TCCGCATGCACCGCCGAAGCCGG	PTGER2	ENSG00000125384	1.3195120002111707	[669]	[466,500,745]	8	hSpCas9	negative selection	1694187
52327235	52327258	14	+	26627737	HeLa	viability after 18 days	GAATGAAACCTCTTCCCGAAAGG	PTGER2	ENSG00000125384	0.5140752909190848	[161]	[23,107,118]	4	hSpCas9	negative selection	1694188
52327338	52327361	14	-	26627737	HeLa	viability after 18 days	GAACGCATTAGTCTCAGAACAGG	PTGER2	ENSG00000125384	-0.26077273817283786	[445]	[155,44,167]	-2	hSpCas9	negative selection	1694189
52314572	52314595	14	-	26627737	HCT116	viability after 6 days	GCGTCTCGCAGTCCTCAGACTGG	PTGER2	ENSG00000125384	0.5651020586015424	[566]	[205,90]	3	hSpCas9	negative selection	1776499
52314742	52314765	14	-	26627737	HCT116	viability after 6 days	GGTCACCAGCACGTGGAACAAGG	PTGER2	ENSG00000125384	0.13981075122667977	[605]	[64,126]	0	hSpCas9	negative selection	1776500
52315105	52315128	14	+	26627737	HCT116	viability after 6 days	GGTGCTTCATCCGGCACGGGCGG	PTGER2	ENSG00000125384	1.586107360111579	[158]	[192,9]	7	hSpCas9	negative selection	1776501
52315216	52315239	14	+	26627737	HCT116	viability after 6 days	TCCGCATGCACCGCCGAAGCCGG	PTGER2	ENSG00000125384	0.26324070501520214	[1910]	[745,147]	1	hSpCas9	negative selection	1776502
52327235	52327258	14	+	26627737	HCT116	viability after 6 days	GAATGAAACCTCTTCCCGAAAGG	PTGER2	ENSG00000125384	-0.9397615720168353	[816]	[55,72]	-5	hSpCas9	negative selection	1776503
52327338	52327361	14	-	26627737	HCT116	viability after 6 days	GAACGCATTAGTCTCAGAACAGG	PTGER2	ENSG00000125384	1.6352733051862933	[640]	[80,440]	8	hSpCas9	negative selection	1776504
52314572	52314595	14	-	26627737	HCT116	viability after 8 days	GCGTCTCGCAGTCCTCAGACTGG	PTGER2	ENSG00000125384	0.2073348897120112	[419]	[214,345,239]	2	hSpCas9	negative selection	1858814
52314742	52314765	14	-	26627737	HCT116	viability after 8 days	GGTCACCAGCACGTGGAACAAGG	PTGER2	ENSG00000125384	0.6875992625007967	[255]	[221,273,185]	6	hSpCas9	negative selection	1858815
52315105	52315128	14	+	26627737	HCT116	viability after 8 days	GGTGCTTCATCCGGCACGGGCGG	PTGER2	ENSG00000125384	0.10284862685588458	[100]	[79,67,31]	1	hSpCas9	negative selection	1858816
52315216	52315239	14	+	26627737	HCT116	viability after 8 days	TCCGCATGCACCGCCGAAGCCGG	PTGER2	ENSG00000125384	0.18414453971303124	[776]	[509,402,545]	2	hSpCas9	negative selection	1858817
52327235	52327258	14	+	26627737	HCT116	viability after 8 days	GAATGAAACCTCTTCCCGAAAGG	PTGER2	ENSG00000125384	1.1303758641069024	[122]	[214,139,91]	8	hSpCas9	negative selection	1858818
52327338	52327361	14	-	26627737	HCT116	viability after 8 days	GAACGCATTAGTCTCAGAACAGG	PTGER2	ENSG00000125384	0.9442455132664442	[197]	[209,225,193]	8	hSpCas9	negative selection	1858819
52314572	52314595	14	-	26627737	HCT116	viability after 9 days	GCGTCTCGCAGTCCTCAGACTGG	PTGER2	ENSG00000125384	0.7457530112581326	[566]	[235,267]	5	hSpCas9	negative selection	1941129
52314742	52314765	14	-	26627737	HCT116	viability after 9 days	GGTCACCAGCACGTGGAACAAGG	PTGER2	ENSG00000125384	0.41182110866424004	[605]	[226,205]	3	hSpCas9	negative selection	1941130
52315105	52315128	14	+	26627737	HCT116	viability after 9 days	GGTGCTTCATCCGGCACGGGCGG	PTGER2	ENSG00000125384	0.15359262804742446	[158]	[25,63]	1	hSpCas9	negative selection	1941131
52315216	52315239	14	+	26627737	HCT116	viability after 9 days	TCCGCATGCACCGCCGAAGCCGG	PTGER2	ENSG00000125384	0.0010140198312871274	[1910]	[599,439]	0	hSpCas9	negative selection	1941132
52327235	52327258	14	+	26627737	HCT116	viability after 9 days	GAATGAAACCTCTTCCCGAAAGG	PTGER2	ENSG00000125384	-2.5523910677190664	[816]	[63,15]	-9	hSpCas9	negative selection	1941133
52327338	52327361	14	-	26627737	HCT116	viability after 9 days	GAACGCATTAGTCTCAGAACAGG	PTGER2	ENSG00000125384	0.1364347587224621	[640]	[224,158]	1	hSpCas9	negative selection	1941134
52314572	52314595	14	-	26627737	HCT116	viability after 12 days	GCGTCTCGCAGTCCTCAGACTGG	PTGER2	ENSG00000125384	-0.49171345856682175	[419]	[150,179,140]	-5	hSpCas9	negative selection	2023444
52314742	52314765	14	-	26627737	HCT116	viability after 12 days	GGTCACCAGCACGTGGAACAAGG	PTGER2	ENSG00000125384	0.2938934735498867	[255]	[212,99,175]	3	hSpCas9	negative selection	2023445
52315105	52315128	14	+	26627737	HCT116	viability after 12 days	GGTGCTTCATCCGGCACGGGCGG	PTGER2	ENSG00000125384	-0.28013736865394234	[100]	[91,6,26]	-3	hSpCas9	negative selection	2023446
52315216	52315239	14	+	26627737	HCT116	viability after 12 days	TCCGCATGCACCGCCGAAGCCGG	PTGER2	ENSG00000125384	0.03634877086171717	[776]	[424,471,359]	0	hSpCas9	negative selection	2023447
52327235	52327258	14	+	26627737	HCT116	viability after 12 days	GAATGAAACCTCTTCCCGAAAGG	PTGER2	ENSG00000125384	0.9875324162156012	[122]	[134,90,156]	8	hSpCas9	negative selection	2023448
52327338	52327361	14	-	26627737	HCT116	viability after 12 days	GAACGCATTAGTCTCAGAACAGG	PTGER2	ENSG00000125384	1.159098378901391	[197]	[255,271,167]	8	hSpCas9	negative selection	2023449
52314572	52314595	14	-	26627737	HCT116	viability after 15 days	GCGTCTCGCAGTCCTCAGACTGG	PTGER2	ENSG00000125384	0.08859413823797258	[419]	[292,399,82]	0	hSpCas9	negative selection	2105759
52314742	52314765	14	-	26627737	HCT116	viability after 15 days	GGTCACCAGCACGTGGAACAAGG	PTGER2	ENSG00000125384	0.8478467076497538	[255]	[451,213,151]	7	hSpCas9	negative selection	2105760
52315105	52315128	14	+	26627737	HCT116	viability after 15 days	GGTGCTTCATCCGGCACGGGCGG	PTGER2	ENSG00000125384	0.008239470534201265	[100]	[87,63,26]	0	hSpCas9	negative selection	2105761
52315216	52315239	14	+	26627737	HCT116	viability after 15 days	TCCGCATGCACCGCCGAAGCCGG	PTGER2	ENSG00000125384	0.36428589638022135	[776]	[741,542,459]	3	hSpCas9	negative selection	2105762
52327235	52327258	14	+	26627737	HCT116	viability after 15 days	GAATGAAACCTCTTCCCGAAAGG	PTGER2	ENSG00000125384	0.6778141112302346	[122]	[76,92,163]	6	hSpCas9	negative selection	2105763
52327338	52327361	14	-	26627737	HCT116	viability after 15 days	GAACGCATTAGTCTCAGAACAGG	PTGER2	ENSG00000125384	1.0549341994976014	[197]	[264,273,173]	8	hSpCas9	negative selection	2105764
52314572	52314595	14	-	26627737	HCT116	viability after 18 days	GCGTCTCGCAGTCCTCAGACTGG	PTGER2	ENSG00000125384	-0.1724404691647593	[419]	[168,291,66]	-1	hSpCas9	negative selection	2188074
52314742	52314765	14	-	26627737	HCT116	viability after 18 days	GGTCACCAGCACGTGGAACAAGG	PTGER2	ENSG00000125384	1.1210707032356422	[255]	[376,229,199]	8	hSpCas9	negative selection	2188075
52315105	52315128	14	+	26627737	HCT116	viability after 18 days	GGTGCTTCATCCGGCACGGGCGG	PTGER2	ENSG00000125384	-0.21294483844047662	[100]	[86,26,11]	-2	hSpCas9	negative selection	2188076
52315216	52315239	14	+	26627737	HCT116	viability after 18 days	TCCGCATGCACCGCCGAAGCCGG	PTGER2	ENSG00000125384	0.6066993420746085	[776]	[578,620,509]	5	hSpCas9	negative selection	2188077
52327235	52327258	14	+	26627737	HCT116	viability after 18 days	GAATGAAACCTCTTCCCGAAAGG	PTGER2	ENSG00000125384	0.8033494177179408	[122]	[86,121,100]	6	hSpCas9	negative selection	2188078
52327338	52327361	14	-	26627737	HCT116	viability after 18 days	GAACGCATTAGTCTCAGAACAGG	PTGER2	ENSG00000125384	0.9086132214625392	[197]	[155,232,144]	7	hSpCas9	negative selection	2188079
52325021	52325044	14	+	25494202	A375	resistance to PLX-4720 (puromycin)	CCCAGCTACTCAGGAGGCTGCAG	PTGER2	ENSG00000125384	1.0101159834039155	[15,74]	[1,39]	4	dCas9-VP64	positive selection	2458771
52325021	52325044	14	+	25494202	A375	resistance to PLX-4720 (zeocin)	CCCAGCTACTCAGGAGGCTGCAG	PTGER2	ENSG00000125384	-0.13736370075198145	[6,190]	[3,51]	-1	dCas9-VP64	positive selection	2554026
52314811	52314834	14	+	27260157	DLD1	viability	TGGTACTGGCTTCGTACGCGCGG	PTGER2	ENSG00000125384	0.534405484388093	[]	[]	8	hSpCas9	negative selection	2574614
52314580	52314603	14	+	27260157	DLD1	viability	AGGACTGCGAGACGCGACAGTGG	PTGER2	ENSG00000125384	0.770340933683356	[]	[]	8	hSpCas9	negative selection	2578653
52315312	52315335	14	-	27260157	DLD1	viability	GTGGTCCGTCTCCTCCGCCATGG	PTGER2	ENSG00000125384	1.86944779669689	[]	[]	9	hSpCas9	negative selection	2579529
52315216	52315239	14	+	27260157	DLD1	viability	TCCGCATGCACCGCCGAAGCCGG	PTGER2	ENSG00000125384	-1.00184034295812	[]	[]	-7	hSpCas9	negative selection	2580102
52315383	52315406	14	-	27260157	DLD1	viability	AGGGAGTGACTTACCGTGAAAGG	PTGER2	ENSG00000125384	0.998373927372308	[]	[]	9	hSpCas9	negative selection	2580804
52314571	52314594	14	-	27260157	DLD1	viability	CGTCTCGCAGTCCTCAGACTGGG	PTGER2	ENSG00000125384	-1.58224314834632	[]	[]	-8	hSpCas9	negative selection	2584204
52315211	52315234	14	-	27260157	DLD1	viability	TTCGGCGGTGCATGCGGATGAGG	PTGER2	ENSG00000125384	-0.52889283283259	[]	[]	-4	hSpCas9	negative selection	2584735
52314806	52314829	14	-	27260157	DLD1	viability	CGTACGAAGCCAGTACCACTGGG	PTGER2	ENSG00000125384	-0.428038387340981	[]	[]	-4	hSpCas9	negative selection	2585992
52315226	52315249	14	-	27260157	DLD1	viability	AGCGGCTTCTCCGGCTTCGGCGG	PTGER2	ENSG00000125384	0.710632101622361	[]	[]	8	hSpCas9	negative selection	2608064
52314858	52314881	14	-	27260157	DLD1	viability	TAGGTGCACGCGCGGCTCTCGGG	PTGER2	ENSG00000125384	-1.11486936434748	[]	[]	-7	hSpCas9	negative selection	2608942
52314908	52314931	14	-	27260157	DLD1	viability	AGAGCATGAGCATCGTGGCCAGG	PTGER2	ENSG00000125384	0.466997580163629	[]	[]	8	hSpCas9	negative selection	2609472
52314626	52314649	14	+	27260157	DLD1	viability	CATCAGCTCCGTCATGTTCTCGG	PTGER2	ENSG00000125384	-0.785257088275872	[]	[]	-6	hSpCas9	negative selection	2610195
52314620	52314643	14	-	27260157	DLD1	viability	ACATGACGGAGCTGATGGCTGGG	PTGER2	ENSG00000125384	0.755824330927938	[]	[]	8	hSpCas9	negative selection	2614087
52314942	52314965	14	+	27260157	DLD1	viability	CTGGAGCGCTACCTCTCGATCGG	PTGER2	ENSG00000125384	0.473776973936005	[]	[]	8	hSpCas9	negative selection	2614395
52314968	52314991	14	-	27260157	DLD1	viability	CGCGGCGCTGGTAGAAGTAGGGG	PTGER2	ENSG00000125384	-1.13088077658898	[]	[]	-7	hSpCas9	negative selection	2619672
52315077	52315100	14	+	27260157	DLD1	viability	CAGTACGTCCAGTACTGCCCCGG	PTGER2	ENSG00000125384	0.754338273697956	[]	[]	8	hSpCas9	negative selection	2623320
52314877	52314900	14	-	27260157	DLD1	viability	GGTCATGGCGAAAGCGAAGTAGG	PTGER2	ENSG00000125384	-0.310695213629819	[]	[]	-3	hSpCas9	negative selection	2640913
52315343	52315366	14	-	27260157	DLD1	viability	AGGTGATGGTCATGATAGCCAGG	PTGER2	ENSG00000125384	0.483306777643158	[]	[]	8	hSpCas9	negative selection	2641514
52315115	52315138	14	-	27260157	DLD1	viability	GGTAAGCGGTCCGCCCGTGCCGG	PTGER2	ENSG00000125384	-1.10815385627927	[]	[]	-7	hSpCas9	negative selection	2641565
52315241	52315264	14	+	27260157	DLD1	viability	AAGCCGCTGCGGACCTTCCCTGG	PTGER2	ENSG00000125384	0.306186461222098	[]	[]	4	hSpCas9	negative selection	2647300
52314811	52314834	14	+	27260157	HT1080	viability	TGGTACTGGCTTCGTACGCGCGG	PTGER2	ENSG00000125384	0.527617907716671	[]	[]	4	hSpCas9	negative selection	2650744
52314580	52314603	14	+	27260157	HT1080	viability	AGGACTGCGAGACGCGACAGTGG	PTGER2	ENSG00000125384	1.11699942711648	[]	[]	8	hSpCas9	negative selection	2654783
52315312	52315335	14	-	27260157	HT1080	viability	GTGGTCCGTCTCCTCCGCCATGG	PTGER2	ENSG00000125384	2.29922442691074	[]	[]	9	hSpCas9	negative selection	2655659
52315216	52315239	14	+	27260157	HT1080	viability	TCCGCATGCACCGCCGAAGCCGG	PTGER2	ENSG00000125384	-3.24364928693444	[]	[]	-9	hSpCas9	negative selection	2656232
52315383	52315406	14	-	27260157	HT1080	viability	AGGGAGTGACTTACCGTGAAAGG	PTGER2	ENSG00000125384	2.00502150080719	[]	[]	9	hSpCas9	negative selection	2656934
52314571	52314594	14	-	27260157	HT1080	viability	CGTCTCGCAGTCCTCAGACTGGG	PTGER2	ENSG00000125384	-0.448895155386176	[]	[]	-7	hSpCas9	negative selection	2660334
52315211	52315234	14	-	27260157	HT1080	viability	TTCGGCGGTGCATGCGGATGAGG	PTGER2	ENSG00000125384	-0.824258183672019	[]	[]	-8	hSpCas9	negative selection	2660865
52314806	52314829	14	-	27260157	HT1080	viability	CGTACGAAGCCAGTACCACTGGG	PTGER2	ENSG00000125384	-0.615541421420421	[]	[]	-8	hSpCas9	negative selection	2662122
52315226	52315249	14	-	27260157	HT1080	viability	AGCGGCTTCTCCGGCTTCGGCGG	PTGER2	ENSG00000125384	0.394146705316379	[]	[]	3	hSpCas9	negative selection	2684194
52314858	52314881	14	-	27260157	HT1080	viability	TAGGTGCACGCGCGGCTCTCGGG	PTGER2	ENSG00000125384	-0.383269460799302	[]	[]	-7	hSpCas9	negative selection	2685072
52314908	52314931	14	-	27260157	HT1080	viability	AGAGCATGAGCATCGTGGCCAGG	PTGER2	ENSG00000125384	2.04656657239956	[]	[]	9	hSpCas9	negative selection	2685602
52314626	52314649	14	+	27260157	HT1080	viability	CATCAGCTCCGTCATGTTCTCGG	PTGER2	ENSG00000125384	-0.311010200582149	[]	[]	-7	hSpCas9	negative selection	2686325
52314620	52314643	14	-	27260157	HT1080	viability	ACATGACGGAGCTGATGGCTGGG	PTGER2	ENSG00000125384	1.54955658130709	[]	[]	9	hSpCas9	negative selection	2690217
52314942	52314965	14	+	27260157	HT1080	viability	CTGGAGCGCTACCTCTCGATCGG	PTGER2	ENSG00000125384	0.654521209892416	[]	[]	6	hSpCas9	negative selection	2690525
52314968	52314991	14	-	27260157	HT1080	viability	CGCGGCGCTGGTAGAAGTAGGGG	PTGER2	ENSG00000125384	-1.71696307355598	[]	[]	-9	hSpCas9	negative selection	2695802
52315077	52315100	14	+	27260157	HT1080	viability	CAGTACGTCCAGTACTGCCCCGG	PTGER2	ENSG00000125384	0.665980549125115	[]	[]	6	hSpCas9	negative selection	2699450
52314877	52314900	14	-	27260157	HT1080	viability	GGTCATGGCGAAAGCGAAGTAGG	PTGER2	ENSG00000125384	0.778940509329027	[]	[]	6	hSpCas9	negative selection	2717043
52315343	52315366	14	-	27260157	HT1080	viability	AGGTGATGGTCATGATAGCCAGG	PTGER2	ENSG00000125384	0.708263073078363	[]	[]	6	hSpCas9	negative selection	2717644
52315115	52315138	14	-	27260157	HT1080	viability	GGTAAGCGGTCCGCCCGTGCCGG	PTGER2	ENSG00000125384	0.121656570748388	[]	[]	1	hSpCas9	negative selection	2717695
52315241	52315264	14	+	27260157	HT1080	viability	AAGCCGCTGCGGACCTTCCCTGG	PTGER2	ENSG00000125384	1.49486117059877	[]	[]	9	hSpCas9	negative selection	2723430
52314811	52314834	14	+	27260157	MKN45	viability	TGGTACTGGCTTCGTACGCGCGG	PTGER2	ENSG00000125384	1.15092969861305	[]	[]	8	hSpCas9	negative selection	2726874
52314580	52314603	14	+	27260157	MKN45	viability	AGGACTGCGAGACGCGACAGTGG	PTGER2	ENSG00000125384	0.553966554653414	[]	[]	7	hSpCas9	negative selection	2730913
52315312	52315335	14	-	27260157	MKN45	viability	GTGGTCCGTCTCCTCCGCCATGG	PTGER2	ENSG00000125384	-0.81524413810498	[]	[]	-7	hSpCas9	negative selection	2731789
52315216	52315239	14	+	27260157	MKN45	viability	TCCGCATGCACCGCCGAAGCCGG	PTGER2	ENSG00000125384	-2.92865292259912	[]	[]	-9	hSpCas9	negative selection	2732362
52315383	52315406	14	-	27260157	MKN45	viability	AGGGAGTGACTTACCGTGAAAGG	PTGER2	ENSG00000125384	0.442184178646494	[]	[]	6	hSpCas9	negative selection	2733064
52314571	52314594	14	-	27260157	MKN45	viability	CGTCTCGCAGTCCTCAGACTGGG	PTGER2	ENSG00000125384	0.990276281994468	[]	[]	8	hSpCas9	negative selection	2736464
52315211	52315234	14	-	27260157	MKN45	viability	TTCGGCGGTGCATGCGGATGAGG	PTGER2	ENSG00000125384	-1.01136963058788	[]	[]	-8	hSpCas9	negative selection	2736995
52314806	52314829	14	-	27260157	MKN45	viability	CGTACGAAGCCAGTACCACTGGG	PTGER2	ENSG00000125384	-0.456977210478805	[]	[]	-6	hSpCas9	negative selection	2738252
52315226	52315249	14	-	27260157	MKN45	viability	AGCGGCTTCTCCGGCTTCGGCGG	PTGER2	ENSG00000125384	-0.474611108873007	[]	[]	-6	hSpCas9	negative selection	2760324
52314858	52314881	14	-	27260157	MKN45	viability	TAGGTGCACGCGCGGCTCTCGGG	PTGER2	ENSG00000125384	-1.82381298271101	[]	[]	-9	hSpCas9	negative selection	2761202
52314908	52314931	14	-	27260157	MKN45	viability	AGAGCATGAGCATCGTGGCCAGG	PTGER2	ENSG00000125384	0.813690108425355	[]	[]	8	hSpCas9	negative selection	2761732
52314626	52314649	14	+	27260157	MKN45	viability	CATCAGCTCCGTCATGTTCTCGG	PTGER2	ENSG00000125384	-0.521315111874014	[]	[]	-6	hSpCas9	negative selection	2762455
52314620	52314643	14	-	27260157	MKN45	viability	ACATGACGGAGCTGATGGCTGGG	PTGER2	ENSG00000125384	0.787519922222922	[]	[]	7	hSpCas9	negative selection	2766347
52314942	52314965	14	+	27260157	MKN45	viability	CTGGAGCGCTACCTCTCGATCGG	PTGER2	ENSG00000125384	0.186502050356839	[]	[]	5	hSpCas9	negative selection	2766655
52314968	52314991	14	-	27260157	MKN45	viability	CGCGGCGCTGGTAGAAGTAGGGG	PTGER2	ENSG00000125384	-2.63051397039074	[]	[]	-9	hSpCas9	negative selection	2771932
52315077	52315100	14	+	27260157	MKN45	viability	CAGTACGTCCAGTACTGCCCCGG	PTGER2	ENSG00000125384	-0.361678133185141	[]	[]	-1	hSpCas9	negative selection	2775580
52314877	52314900	14	-	27260157	MKN45	viability	GGTCATGGCGAAAGCGAAGTAGG	PTGER2	ENSG00000125384	-1.36805323061858	[]	[]	-8	hSpCas9	negative selection	2793173
52315343	52315366	14	-	27260157	MKN45	viability	AGGTGATGGTCATGATAGCCAGG	PTGER2	ENSG00000125384	0.138219845628206	[]	[]	5	hSpCas9	negative selection	2793774
52315115	52315138	14	-	27260157	MKN45	viability	GGTAAGCGGTCCGCCCGTGCCGG	PTGER2	ENSG00000125384	-0.353610336424481	[]	[]	-1	hSpCas9	negative selection	2793825
52315241	52315264	14	+	27260157	MKN45	viability	AAGCCGCTGCGGACCTTCCCTGG	PTGER2	ENSG00000125384	0.859762811939914	[]	[]	8	hSpCas9	negative selection	2799560
52314811	52314834	14	+	27260157	RKO	viability	TGGTACTGGCTTCGTACGCGCGG	PTGER2	ENSG00000125384	-0.568222737742477	[]	[]	-7	hSpCas9	negative selection	2803004
52314580	52314603	14	+	27260157	RKO	viability	AGGACTGCGAGACGCGACAGTGG	PTGER2	ENSG00000125384	0.924332200364425	[]	[]	8	hSpCas9	negative selection	2807043
52315312	52315335	14	-	27260157	RKO	viability	GTGGTCCGTCTCCTCCGCCATGG	PTGER2	ENSG00000125384	-0.0204739937906323	[]	[]	0	hSpCas9	negative selection	2807919
52315216	52315239	14	+	27260157	RKO	viability	TCCGCATGCACCGCCGAAGCCGG	PTGER2	ENSG00000125384	-1.91928669663182	[]	[]	-9	hSpCas9	negative selection	2808492
52315383	52315406	14	-	27260157	RKO	viability	AGGGAGTGACTTACCGTGAAAGG	PTGER2	ENSG00000125384	1.29056675364164	[]	[]	9	hSpCas9	negative selection	2809194
52314571	52314594	14	-	27260157	RKO	viability	CGTCTCGCAGTCCTCAGACTGGG	PTGER2	ENSG00000125384	-2.11539168132822	[]	[]	-9	hSpCas9	negative selection	2812594
52315211	52315234	14	-	27260157	RKO	viability	TTCGGCGGTGCATGCGGATGAGG	PTGER2	ENSG00000125384	-0.0884765898199151	[]	[]	0	hSpCas9	negative selection	2813125
52314806	52314829	14	-	27260157	RKO	viability	CGTACGAAGCCAGTACCACTGGG	PTGER2	ENSG00000125384	0.285232908707099	[]	[]	1	hSpCas9	negative selection	2814382
52315226	52315249	14	-	27260157	RKO	viability	AGCGGCTTCTCCGGCTTCGGCGG	PTGER2	ENSG00000125384	-0.0534983595494893	[]	[]	0	hSpCas9	negative selection	2836454
52314858	52314881	14	-	27260157	RKO	viability	TAGGTGCACGCGCGGCTCTCGGG	PTGER2	ENSG00000125384	-0.879357043056862	[]	[]	-8	hSpCas9	negative selection	2837332
52314908	52314931	14	-	27260157	RKO	viability	AGAGCATGAGCATCGTGGCCAGG	PTGER2	ENSG00000125384	0.755894989264294	[]	[]	8	hSpCas9	negative selection	2837862
52314626	52314649	14	+	27260157	RKO	viability	CATCAGCTCCGTCATGTTCTCGG	PTGER2	ENSG00000125384	-0.50549010162631	[]	[]	-6	hSpCas9	negative selection	2838585
52314620	52314643	14	-	27260157	RKO	viability	ACATGACGGAGCTGATGGCTGGG	PTGER2	ENSG00000125384	1.20306908779332	[]	[]	9	hSpCas9	negative selection	2842477
52314942	52314965	14	+	27260157	RKO	viability	CTGGAGCGCTACCTCTCGATCGG	PTGER2	ENSG00000125384	0.566470789177545	[]	[]	3	hSpCas9	negative selection	2842785
52314968	52314991	14	-	27260157	RKO	viability	CGCGGCGCTGGTAGAAGTAGGGG	PTGER2	ENSG00000125384	-2.57712083369752	[]	[]	-9	hSpCas9	negative selection	2848062
52315077	52315100	14	+	27260157	RKO	viability	CAGTACGTCCAGTACTGCCCCGG	PTGER2	ENSG00000125384	-0.197299320187437	[]	[]	-1	hSpCas9	negative selection	2851710
52314877	52314900	14	-	27260157	RKO	viability	GGTCATGGCGAAAGCGAAGTAGG	PTGER2	ENSG00000125384	-0.590898393867227	[]	[]	-7	hSpCas9	negative selection	2869303
52315343	52315366	14	-	27260157	RKO	viability	AGGTGATGGTCATGATAGCCAGG	PTGER2	ENSG00000125384	1.48347257913687	[]	[]	9	hSpCas9	negative selection	2869904
52315115	52315138	14	-	27260157	RKO	viability	GGTAAGCGGTCCGCCCGTGCCGG	PTGER2	ENSG00000125384	0.143695629683378	[]	[]	0	hSpCas9	negative selection	2869955
52315241	52315264	14	+	27260157	RKO	viability	AAGCCGCTGCGGACCTTCCCTGG	PTGER2	ENSG00000125384	1.75881538281704	[]	[]	9	hSpCas9	negative selection	2875690
52314811	52314834	14	+	27260157	SF268	viability	TGGTACTGGCTTCGTACGCGCGG	PTGER2	ENSG00000125384	0.379127384774099	[]	[]	4	hSpCas9	negative selection	2879134
52314580	52314603	14	+	27260157	SF268	viability	AGGACTGCGAGACGCGACAGTGG	PTGER2	ENSG00000125384	0.685194903339536	[]	[]	8	hSpCas9	negative selection	2883173
52315312	52315335	14	-	27260157	SF268	viability	GTGGTCCGTCTCCTCCGCCATGG	PTGER2	ENSG00000125384	-0.614748711446636	[]	[]	-5	hSpCas9	negative selection	2884049
52315216	52315239	14	+	27260157	SF268	viability	TCCGCATGCACCGCCGAAGCCGG	PTGER2	ENSG00000125384	-1.01084286172123	[]	[]	-7	hSpCas9	negative selection	2884622
52315383	52315406	14	-	27260157	SF268	viability	AGGGAGTGACTTACCGTGAAAGG	PTGER2	ENSG00000125384	1.05095366035176	[]	[]	9	hSpCas9	negative selection	2885324
52314571	52314594	14	-	27260157	SF268	viability	CGTCTCGCAGTCCTCAGACTGGG	PTGER2	ENSG00000125384	-0.77655404318217	[]	[]	-6	hSpCas9	negative selection	2888724
52315211	52315234	14	-	27260157	SF268	viability	TTCGGCGGTGCATGCGGATGAGG	PTGER2	ENSG00000125384	-1.38125546841485	[]	[]	-7	hSpCas9	negative selection	2889255
52314806	52314829	14	-	27260157	SF268	viability	CGTACGAAGCCAGTACCACTGGG	PTGER2	ENSG00000125384	0.217027220280779	[]	[]	3	hSpCas9	negative selection	2890512
52315226	52315249	14	-	27260157	SF268	viability	AGCGGCTTCTCCGGCTTCGGCGG	PTGER2	ENSG00000125384	0.583644225994532	[]	[]	8	hSpCas9	negative selection	2912584
52314858	52314881	14	-	27260157	SF268	viability	TAGGTGCACGCGCGGCTCTCGGG	PTGER2	ENSG00000125384	-1.62536704084189	[]	[]	-8	hSpCas9	negative selection	2913462
52314908	52314931	14	-	27260157	SF268	viability	AGAGCATGAGCATCGTGGCCAGG	PTGER2	ENSG00000125384	1.23834586975206	[]	[]	9	hSpCas9	negative selection	2913992
52314626	52314649	14	+	27260157	SF268	viability	CATCAGCTCCGTCATGTTCTCGG	PTGER2	ENSG00000125384	-0.701469171804586	[]	[]	-5	hSpCas9	negative selection	2914715
52314620	52314643	14	-	27260157	SF268	viability	ACATGACGGAGCTGATGGCTGGG	PTGER2	ENSG00000125384	1.47953648812468	[]	[]	9	hSpCas9	negative selection	2918607
52314942	52314965	14	+	27260157	SF268	viability	CTGGAGCGCTACCTCTCGATCGG	PTGER2	ENSG00000125384	0.547357428643215	[]	[]	8	hSpCas9	negative selection	2918915
52314968	52314991	14	-	27260157	SF268	viability	CGCGGCGCTGGTAGAAGTAGGGG	PTGER2	ENSG00000125384	-2.29454929367448	[]	[]	-9	hSpCas9	negative selection	2924192
52315077	52315100	14	+	27260157	SF268	viability	CAGTACGTCCAGTACTGCCCCGG	PTGER2	ENSG00000125384	0.111977861167463	[]	[]	0	hSpCas9	negative selection	2927840
52314877	52314900	14	-	27260157	SF268	viability	GGTCATGGCGAAAGCGAAGTAGG	PTGER2	ENSG00000125384	-0.517431972039695	[]	[]	-4	hSpCas9	negative selection	2945433
52315343	52315366	14	-	27260157	SF268	viability	AGGTGATGGTCATGATAGCCAGG	PTGER2	ENSG00000125384	0.346285767945063	[]	[]	4	hSpCas9	negative selection	2946034
52315115	52315138	14	-	27260157	SF268	viability	GGTAAGCGGTCCGCCCGTGCCGG	PTGER2	ENSG00000125384	-0.144765890717437	[]	[]	-1	hSpCas9	negative selection	2946085
52315241	52315264	14	+	27260157	SF268	viability	AAGCCGCTGCGGACCTTCCCTGG	PTGER2	ENSG00000125384	0.638345925632877	[]	[]	8	hSpCas9	negative selection	2951820
52314736	52314759	14	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CAGCACGTGGAACAAGGAGAGGG	PTGER2	ENSG00000125384	0.27660752579117953	[4,4]	[5,4]	6	hSpCas9	positive selection	3014566
52314806	52314829	14	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CGTACGAAGCCAGTACCACTGGG	PTGER2	ENSG00000125384	0.30424346520476975	[4,3]	[4,4]	6	hSpCas9	positive selection	3014567
52314792	52314815	14	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GACCTGCCTCATCAGCCCAGTGG	PTGER2	ENSG00000125384	0.1970987689479471	[2,3]	[4,1]	4	hSpCas9	positive selection	3014568
52315059	52315082	14	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TACTGCCCATAGTCCAGCAGCGG	PTGER2	ENSG00000125384	0.2868411465912601	[4,3]	[3,4]	6	hSpCas9	positive selection	3014569
52314736	52314759	14	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CAGCACGTGGAACAAGGAGAGGG	PTGER2	ENSG00000125384	0.4196094786586372	[4,4]	[5,4]	7	hSpCas9	positive selection	3082424
52314806	52314829	14	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CGTACGAAGCCAGTACCACTGGG	PTGER2	ENSG00000125384	0.2461330788802527	[4,4]	[3,3]	4	hSpCas9	positive selection	3082425
52314792	52314815	14	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GACCTGCCTCATCAGCCCAGTGG	PTGER2	ENSG00000125384	-0.30463096153833424	[2,2]	[1,0]	-4	hSpCas9	positive selection	3082426
52315059	52315082	14	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TACTGCCCATAGTCCAGCAGCGG	PTGER2	ENSG00000125384	0.30131893957871836	[4,4]	[2,4]	5	hSpCas9	positive selection	3082427
52327261	52327284		+	24336571	A375	resistance to PLX after 7 days	AATGGGACCTCCAAGCTCTTAGG	PTGER2	ENSG00000125384	0.09863199719549176	[6,5]	[5,7]	3	hSpCas9	positive selection	3138648
52314942	52314965		+	24336571	A375	resistance to PLX after 7 days	CTGGAGCGCTACCTCTCGATCGG	PTGER2	ENSG00000125384	-0.1262074467538689	[17,13]	[13,14]	-4	hSpCas9	positive selection	3138649
52327235	52327258		+	24336571	A375	resistance to PLX after 7 days	GAATGAAACCTCTTCCCGAAAGG	PTGER2	ENSG00000125384	-0.1134860694267723	[4,5]	[4,4]	-4	hSpCas9	positive selection	3138650
52314572	52314595		-	24336571	A375	resistance to PLX after 7 days	GCGTCTCGCAGTCCTCAGACTGG	PTGER2	ENSG00000125384	0.09373068511966975	[3,4]	[4,3]	3	hSpCas9	positive selection	3138651
52327261	52327284		+	24336571	A375	resistance to PLX after 14 days	AATGGGACCTCCAAGCTCTTAGG	PTGER2	ENSG00000125384	0.35692696727669015	[2,4]	[1,2]	3	hSpCas9	positive selection	3196441
52314942	52314965		+	24336571	A375	resistance to PLX after 14 days	CTGGAGCGCTACCTCTCGATCGG	PTGER2	ENSG00000125384	1.10298749767614	[20,10]	[16,14]	8	hSpCas9	positive selection	3196442
52327235	52327258		+	24336571	A375	resistance to PLX after 14 days	GAATGAAACCTCTTCCCGAAAGG	PTGER2	ENSG00000125384	1.5230263967348918	[2,2]	[3,4]	9	hSpCas9	positive selection	3196443
52314572	52314595		-	24336571	A375	resistance to PLX after 14 days	GCGTCTCGCAGTCCTCAGACTGG	PTGER2	ENSG00000125384	0.1731362125278002	[4,2]	[1,1]	1	hSpCas9	positive selection	3196444
52327261	52327284		+	24336571	A375	viability after 7 days	AATGGGACCTCCAAGCTCTTAGG	PTGER2	ENSG00000125384	-0.2587430263484526	[7]	[6,5]	-4	hSpCas9	negative selection	3254234
52314942	52314965		+	24336571	A375	viability after 7 days	CTGGAGCGCTACCTCTCGATCGG	PTGER2	ENSG00000125384	0.5710381585492037	[10]	[17,13]	8	hSpCas9	negative selection	3254235
52327235	52327258		+	24336571	A375	viability after 7 days	GAATGAAACCTCTTCCCGAAAGG	PTGER2	ENSG00000125384	0.23534812317437281	[4]	[4,5]	3	hSpCas9	negative selection	3254236
52314572	52314595		-	24336571	A375	viability after 7 days	GCGTCTCGCAGTCCTCAGACTGG	PTGER2	ENSG00000125384	-0.22492030119495499	[5]	[3,4]	-3	hSpCas9	negative selection	3254237
52327261	52327284		+	24336571	A375	viability after 14 days	AATGGGACCTCCAAGCTCTTAGG	PTGER2	ENSG00000125384	-0.7752286604800263	[7]	[2,4]	-7	hSpCas9	negative selection	3312027
52314942	52314965		+	24336571	A375	viability after 14 days	CTGGAGCGCTACCTCTCGATCGG	PTGER2	ENSG00000125384	0.5949325086809744	[10]	[20,10]	7	hSpCas9	negative selection	3312028
52327235	52327258		+	24336571	A375	viability after 14 days	GAATGAAACCTCTTCCCGAAAGG	PTGER2	ENSG00000125384	-0.5461538975430078	[4]	[2,2]	-6	hSpCas9	negative selection	3312029
52314572	52314595		-	24336571	A375	viability after 14 days	GCGTCTCGCAGTCCTCAGACTGG	PTGER2	ENSG00000125384	-0.2988927266116326	[5]	[4,2]	-4	hSpCas9	negative selection	3312030
52327364	52327387	14	-	27383988	293T	resistance to West Nile virus (flavivirus)	TTAATGAAATCCGACAACAGAGG	PTGER2	ENSG00000125384	0.7815927804794374	[88,88]	[0,0]	4	hSpCas9	positive selection	3388161
52314634	52314657	14	-	27383988	293T	resistance to West Nile virus (flavivirus)	CACCCCGGCCGAGAACATGACGG	PTGER2	ENSG00000125384	0.009398698002249677	[151,151]	[0,0]	0	hSpCas9	positive selection	3388162
52314877	52314900	14	-	27383988	293T	resistance to West Nile virus (flavivirus)	GGTCATGGCGAAAGCGAAGTAGG	PTGER2	ENSG00000125384	3.3504356158373163	[14,14]	[0,0]	9	hSpCas9	positive selection	3388163
52314736	52314759	14	-	26780180	HT29	viability (Avana library 4 designs)	CAGCACGTGGAACAAGGAGAGGG	PTGER2	ENSG00000125384	0.841246210858385	[]	[]	3	hSpCas9	negative selection	3452806
52314806	52314829	14	-	26780180	HT29	viability (Avana library 4 designs)	CGTACGAAGCCAGTACCACTGGG	PTGER2	ENSG00000125384	-0.295092101599691	[]	[]	-5	hSpCas9	negative selection	3452807
52314791	52314814	14	+	26780180	HT29	viability (Avana library 4 designs)	GACCTGCCTCATCAGCCCAGTGG	PTGER2	ENSG00000125384	0.86693486882401	[]	[]	3	hSpCas9	negative selection	3452808
52315059	52315082	14	-	26780180	HT29	viability (Avana library 4 designs)	TACTGCCCATAGTCCAGCAGCGG	PTGER2	ENSG00000125384	0.541924654499079	[]	[]	2	hSpCas9	negative selection	3452809
52315059	52315082	14	-	26780180	A375	viability (Avana lentiCRISPRv2)	TACTGCCCATAGTCCAGCAGCGG	PTGER2	ENSG00000125384	-0.760830136016594	[]	[]	-1	hSpCas9	negative selection	3549354
52314791	52314814	14	+	26780180	A375	viability (Avana lentiCRISPRv2)	GACCTGCCTCATCAGCCCAGTGG	PTGER2	ENSG00000125384	3.72584191127095	[]	[]	6	hSpCas9	negative selection	3549355
52314806	52314829	14	-	26780180	A375	viability (Avana lentiCRISPRv2)	CGTACGAAGCCAGTACCACTGGG	PTGER2	ENSG00000125384	4.20034738522655	[]	[]	7	hSpCas9	negative selection	3549356
52314736	52314759	14	-	26780180	A375	viability (Avana lentiCRISPRv2)	CAGCACGTGGAACAAGGAGAGGG	PTGER2	ENSG00000125384	1.06939873818806	[]	[]	1	hSpCas9	negative selection	3549357
52314737	52314760	14	-	26780180	A375	viability (Avana lentiCRISPRv2)	CCAGCACGTGGAACAAGGAGAGG	PTGER2	ENSG00000125384	3.56531462637675	[]	[]	5	hSpCas9	negative selection	3549358
52314824	52314847	14	+	26780180	A375	viability (Avana lentiCRISPRv2)	GTACGCGCGGAACCAGACCCTGG	PTGER2	ENSG00000125384	2.96602850041871	[]	[]	4	hSpCas9	negative selection	3549359
52315059	52315082	14	-	26780180	A375	viability (Avana lentiGuide)	TACTGCCCATAGTCCAGCAGCGG	PTGER2	ENSG00000125384	-1.99754817711873	[]	[]	-3	hSpCas9	negative selection	3658013
52314791	52314814	14	+	26780180	A375	viability (Avana lentiGuide)	GACCTGCCTCATCAGCCCAGTGG	PTGER2	ENSG00000125384	9.37454543572628	[]	[]	6	hSpCas9	negative selection	3658014
52314806	52314829	14	-	26780180	A375	viability (Avana lentiGuide)	CGTACGAAGCCAGTACCACTGGG	PTGER2	ENSG00000125384	-3.32438039061087	[]	[]	-6	hSpCas9	negative selection	3658015
52314736	52314759	14	-	26780180	A375	viability (Avana lentiGuide)	CAGCACGTGGAACAAGGAGAGGG	PTGER2	ENSG00000125384	3.34255984552099	[]	[]	3	hSpCas9	negative selection	3658016
52314737	52314760	14	-	26780180	A375	viability (Avana lentiGuide)	CCAGCACGTGGAACAAGGAGAGG	PTGER2	ENSG00000125384	2.93725590360397	[]	[]	3	hSpCas9	negative selection	3658017
52314824	52314847	14	+	26780180	A375	viability (Avana lentiGuide)	GTACGCGCGGAACCAGACCCTGG	PTGER2	ENSG00000125384	-0.603905841501212	[]	[]	-1	hSpCas9	negative selection	3658018
52315059	52315082	14	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TACTGCCCATAGTCCAGCAGCGG	PTGER2	ENSG00000125384	-0.02507495015388515	[5]	[5,4]	0	hSpCas9	positive selection	3766620
52314791	52314814	14	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GACCTGCCTCATCAGCCCAGTGG	PTGER2	ENSG00000125384	0.03766620023417301	[4]	[7,2]	0	hSpCas9	positive selection	3766621
52314806	52314829	14	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CGTACGAAGCCAGTACCACTGGG	PTGER2	ENSG00000125384	0.2986537516536906	[5]	[7,6]	8	hSpCas9	positive selection	3766622
52314736	52314759	14	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CAGCACGTGGAACAAGGAGAGGG	PTGER2	ENSG00000125384	0.12571696359299803	[6]	[6,6]	3	hSpCas9	positive selection	3766623
52314737	52314760	14	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CCAGCACGTGGAACAAGGAGAGG	PTGER2	ENSG00000125384	0.25044122109068023	[4]	[5,5]	7	hSpCas9	positive selection	3766624
52314824	52314847	14	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GTACGCGCGGAACCAGACCCTGG	PTGER2	ENSG00000125384	0.052995558725901226	[4]	[5,4]	1	hSpCas9	positive selection	3766625
52315059	52315082	14	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TACTGCCCATAGTCCAGCAGCGG	PTGER2	ENSG00000125384	0.049953218983766284	[5]	[5,4]	1	hSpCas9	positive selection	3875227
52314791	52314814	14	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GACCTGCCTCATCAGCCCAGTGG	PTGER2	ENSG00000125384	-0.9013460475131856	[4]	[1,2]	-8	hSpCas9	positive selection	3875228
52314806	52314829	14	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CGTACGAAGCCAGTACCACTGGG	PTGER2	ENSG00000125384	0.09542436880586591	[6]	[6,4]	2	hSpCas9	positive selection	3875229
52314736	52314759	14	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CAGCACGTGGAACAAGGAGAGGG	PTGER2	ENSG00000125384	0.07817657460025668	[6]	[6,5]	1	hSpCas9	positive selection	3875230
52314737	52314760	14	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CCAGCACGTGGAACAAGGAGAGG	PTGER2	ENSG00000125384	-0.6877609778307656	[4]	[0,3]	-7	hSpCas9	positive selection	3875231
52314824	52314847	14	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GTACGCGCGGAACCAGACCCTGG	PTGER2	ENSG00000125384	0.1269198054773363	[5]	[4,5]	3	hSpCas9	positive selection	3875232
52314953	52314976	14	-	26780180	A375	viability	AGTAGGGGTGCCCGATCGAGAGG	PTGER2	ENSG00000125384	1.3519977519956	[]	[]	7	hSpCas9	negative selection	3985662
52314634	52314657	14	-	26780180	A375	viability	CACCCCGGCCGAGAACATGACGG	PTGER2	ENSG00000125384	0.598725029788323	[]	[]	1	hSpCas9	negative selection	3985663
52314942	52314965	14	+	26780180	A375	viability	CTGGAGCGCTACCTCTCGATCGG	PTGER2	ENSG00000125384	0.690051971967103	[]	[]	2	hSpCas9	negative selection	3985664
52327235	52327258	14	+	26780180	A375	viability	GAATGAAACCTCTTCCCGAAAGG	PTGER2	ENSG00000125384	0.825323309695034	[]	[]	3	hSpCas9	negative selection	3985665
52314877	52314900	14	-	26780180	A375	viability	GGTCATGGCGAAAGCGAAGTAGG	PTGER2	ENSG00000125384	0.427858022188377	[]	[]	1	hSpCas9	negative selection	3985666
52327364	52327387	14	-	26780180	A375	viability	TTAATGAAATCCGACAACAGAGG	PTGER2	ENSG00000125384	1.44429176232655	[]	[]	8	hSpCas9	negative selection	3985667
52314953	52314976	14	-	26780180	HT29	viability (GeCKOv2 library)	AGTAGGGGTGCCCGATCGAGAGG	PTGER2	ENSG00000125384	1.12786291001745	[]	[]	5	hSpCas9	negative selection	4093628
52314634	52314657	14	-	26780180	HT29	viability (GeCKOv2 library)	CACCCCGGCCGAGAACATGACGG	PTGER2	ENSG00000125384	1.96529195921933	[]	[]	9	hSpCas9	negative selection	4093629
52314942	52314965	14	+	26780180	HT29	viability (GeCKOv2 library)	CTGGAGCGCTACCTCTCGATCGG	PTGER2	ENSG00000125384	1.01354516139858	[]	[]	4	hSpCas9	negative selection	4093630
52327235	52327258	14	+	26780180	HT29	viability (GeCKOv2 library)	GAATGAAACCTCTTCCCGAAAGG	PTGER2	ENSG00000125384	0.764431445128037	[]	[]	3	hSpCas9	negative selection	4093631
52314877	52314900	14	-	26780180	HT29	viability (GeCKOv2 library)	GGTCATGGCGAAAGCGAAGTAGG	PTGER2	ENSG00000125384	0.712831241616337	[]	[]	2	hSpCas9	negative selection	4093632
52327364	52327387	14	-	26780180	HT29	viability (GeCKOv2 library)	TTAATGAAATCCGACAACAGAGG	PTGER2	ENSG00000125384	1.22740187893259	[]	[]	6	hSpCas9	negative selection	4093633
52327261	52327284	14	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	AATGGGACCTCCAAGCTCTTAGG	PTGER2	ENSG00000125384	-0.12991142714012402	[3]	[2,0]	-3	hSpCas9	positive selection	4163902
52314942	52314965	14	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CTGGAGCGCTACCTCTCGATCGG	PTGER2	ENSG00000125384	0.25672551676939603	[3]	[2,3]	6	hSpCas9	positive selection	4163903
52327235	52327258	14	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GAATGAAACCTCTTCCCGAAAGG	PTGER2	ENSG00000125384	-0.17789605131975578	[2]	[0,1]	-4	hSpCas9	positive selection	4163904
52314572	52314595	14	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GCGTCTCGCAGTCCTCAGACTGG	PTGER2	ENSG00000125384	-0.25210467337192544	[1]	[0,0]	-6	hSpCas9	positive selection	4163905
52327261	52327284	14	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	AATGGGACCTCCAAGCTCTTAGG	PTGER2	ENSG00000125384	0.15563602103067864	[2]	[0,2,1,0]	1	hSpCas9	positive selection	4227924
52314942	52314965	14	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CTGGAGCGCTACCTCTCGATCGG	PTGER2	ENSG00000125384	0.3459273841267645	[4]	[3,2,4,0]	2	hSpCas9	positive selection	4227925
52327235	52327258	14	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GAATGAAACCTCTTCCCGAAAGG	PTGER2	ENSG00000125384	-0.31630824400711727	[2]	[0,1,0,0]	-5	hSpCas9	positive selection	4227926
52314572	52314595	14	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GCGTCTCGCAGTCCTCAGACTGG	PTGER2	ENSG00000125384	-0.21179799555046686	[2]	[0,1,0,0]	-3	hSpCas9	positive selection	4227927
52314942	52314965	14	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CTGGAGCGCTACCTCTCGATCGG	PTGER2	ENSG00000125384	0.16593019274342063	[2]	[3,1]	3	hSpCas9	positive selection	4292948
52314953	52314976	14	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AGTAGGGGTGCCCGATCGAGAGG	PTGER2	ENSG00000125384	-0.2978823430276941	[2]	[1,0]	-6	hSpCas9	positive selection	4292949
52327235	52327258	14	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GAATGAAACCTCTTCCCGAAAGG	PTGER2	ENSG00000125384	0.46800150022973064	[2]	[2,2]	8	hSpCas9	positive selection	4292950
52327364	52327387	14	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TTAATGAAATCCGACAACAGAGG	PTGER2	ENSG00000125384	0.25651825092668107	[2]	[2,1]	5	hSpCas9	positive selection	4357207
52314634	52314657	14	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CACCCCGGCCGAGAACATGACGG	PTGER2	ENSG00000125384	0.08152519808203888	[2]	[2,1]	1	hSpCas9	positive selection	4357208
52314877	52314900	14	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GGTCATGGCGAAAGCGAAGTAGG	PTGER2	ENSG00000125384	-0.32765075919787323	[0]	[0,0]	-6	hSpCas9	positive selection	4357209
52314812	52314834	14	+	27760321	OCIAML3	viability	GGTACTGGCTTCGTACGCGCGG	PTGER2	ENSG00000125384	-0.011942971376945777	[732,698]	[480,653]	0	hSpCas9	negative selection	4431713
52314866	52314888	14	-	27760321	OCIAML3	viability	AGCGAAGTAGGTGCACGCGCGG	PTGER2	ENSG00000125384	-0.9175153355059242	[652,522]	[192,305]	-7	hSpCas9	negative selection	4431714
52314913	52314935	14	-	27760321	OCIAML3	viability	GCGAAGAGCATGAGCATCGTGG	PTGER2	ENSG00000125384	-0.1544486294066703	[523,369]	[334,278]	-2	hSpCas9	negative selection	4431715
52314944	52314966	14	+	27760321	OCIAML3	viability	GGAGCGCTACCTCTCGATCGGG	PTGER2	ENSG00000125384	0.08109908112192488	[600,520]	[389,557]	0	hSpCas9	negative selection	4431716
52315059	52315081	14	-	27760321	OCIAML3	viability	ACTGCCCATAGTCCAGCAGCGG	PTGER2	ENSG00000125384	0.6889732985594745	[899,702]	[882,1160]	7	hSpCas9	negative selection	4431717
52314812	52314834	14	+	27760321	OCIAML2	viability	GGTACTGGCTTCGTACGCGCGG	PTGER2	ENSG00000125384	0.4721854919033981	[732,698]	[700,940]	6	hSpCas9	negative selection	4515176
52314866	52314888	14	-	27760321	OCIAML2	viability	AGCGAAGTAGGTGCACGCGCGG	PTGER2	ENSG00000125384	0.17237209383647384	[652,522]	[500,574]	2	hSpCas9	negative selection	4515177
52314913	52314935	14	-	27760321	OCIAML2	viability	GCGAAGAGCATGAGCATCGTGG	PTGER2	ENSG00000125384	0.5597325430103807	[523,369]	[411,678]	7	hSpCas9	negative selection	4515178
52314944	52314966	14	+	27760321	OCIAML2	viability	GGAGCGCTACCTCTCGATCGGG	PTGER2	ENSG00000125384	0.0674491755081611	[600,520]	[384,591]	0	hSpCas9	negative selection	4515179
52315059	52315081	14	-	27760321	OCIAML2	viability	ACTGCCCATAGTCCAGCAGCGG	PTGER2	ENSG00000125384	0.5420599055842252	[899,702]	[862,1035]	7	hSpCas9	negative selection	4515180
52314812	52314834	14	+	27760321	MV411	viability	GGTACTGGCTTCGTACGCGCGG	PTGER2	ENSG00000125384	-0.17146899376393832	[732,698]	[541,236]	-1	hSpCas9	negative selection	4598639
52314866	52314888	14	-	27760321	MV411	viability	AGCGAAGTAGGTGCACGCGCGG	PTGER2	ENSG00000125384	-1.0193823983520602	[652,522]	[85,346]	-6	hSpCas9	negative selection	4598640
52314913	52314935	14	-	27760321	MV411	viability	GCGAAGAGCATGAGCATCGTGG	PTGER2	ENSG00000125384	0.26765834415348305	[523,369]	[413,256]	2	hSpCas9	negative selection	4598641
52314944	52314966	14	+	27760321	MV411	viability	GGAGCGCTACCTCTCGATCGGG	PTGER2	ENSG00000125384	0.029121608588348502	[600,520]	[355,407]	0	hSpCas9	negative selection	4598642
52315059	52315081	14	-	27760321	MV411	viability	ACTGCCCATAGTCCAGCAGCGG	PTGER2	ENSG00000125384	1.2562333644281107	[899,702]	[1277,1219]	8	hSpCas9	negative selection	4598643
52314812	52314834	14	+	27760321	HL60	viability	GGTACTGGCTTCGTACGCGCGG	PTGER2	ENSG00000125384	0.7734569513634308	[732,698]	[1037,961]	8	hSpCas9	negative selection	4682102
52314866	52314888	14	-	27760321	HL60	viability	AGCGAAGTAGGTGCACGCGCGG	PTGER2	ENSG00000125384	-0.06204954094322196	[652,522]	[355,564]	0	hSpCas9	negative selection	4682103
52314913	52314935	14	-	27760321	HL60	viability	GCGAAGAGCATGAGCATCGTGG	PTGER2	ENSG00000125384	1.2390273013069801	[523,369]	[753,956]	9	hSpCas9	negative selection	4682104
52314944	52314966	14	+	27760321	HL60	viability	GGAGCGCTACCTCTCGATCGGG	PTGER2	ENSG00000125384	-0.13311461709668013	[600,520]	[459,370]	-1	hSpCas9	negative selection	4682105
52315059	52315081	14	-	27760321	HL60	viability	ACTGCCCATAGTCCAGCAGCGG	PTGER2	ENSG00000125384	1.222928186775992	[899,702]	[1529,1504]	9	hSpCas9	negative selection	4682106
52314812	52314834	14	+	27760321	HT1080	viability	GGTACTGGCTTCGTACGCGCGG	PTGER2	ENSG00000125384	-0.053573186801960215	[698,545]	[216,262]	0	hSpCas9	negative selection	4765565
52314866	52314888	14	-	27760321	HT1080	viability	AGCGAAGTAGGTGCACGCGCGG	PTGER2	ENSG00000125384	0.8393351489961407	[522,407]	[242,428]	4	hSpCas9	negative selection	4765566
52314913	52314935	14	-	27760321	HT1080	viability	GCGAAGAGCATGAGCATCGTGG	PTGER2	ENSG00000125384	0.1245372973764634	[369,288]	[60,232]	0	hSpCas9	negative selection	4765567
52314944	52314966	14	+	27760321	HT1080	viability	GGAGCGCTACCTCTCGATCGGG	PTGER2	ENSG00000125384	1.1333668635418979	[520,406]	[584,208]	6	hSpCas9	negative selection	4765568
52315059	52315081	14	-	27760321	HT1080	viability	ACTGCCCATAGTCCAGCAGCGG	PTGER2	ENSG00000125384	1.7318984585663033	[702,548]	[709,957]	8	hSpCas9	negative selection	4765569
52314812	52314834	14	+	27760321	HT29	viability after 7 days	GGTACTGGCTTCGTACGCGCGG	PTGER2	ENSG00000125384	-0.3778881608675996	[698,545]	[676,858,328]	-5	hSpCas9	negative selection	4849028
52314866	52314888	14	-	27760321	HT29	viability after 7 days	AGCGAAGTAGGTGCACGCGCGG	PTGER2	ENSG00000125384	-0.28085407297769355	[522,407]	[439,548,480]	-4	hSpCas9	negative selection	4849029
52314913	52314935	14	-	27760321	HT29	viability after 7 days	GCGAAGAGCATGAGCATCGTGG	PTGER2	ENSG00000125384	0.3265802310181368	[369,288]	[526,486,576]	5	hSpCas9	negative selection	4849030
52314944	52314966	14	+	27760321	HT29	viability after 7 days	GGAGCGCTACCTCTCGATCGGG	PTGER2	ENSG00000125384	-0.01531830602281875	[520,406]	[739,511,540]	0	hSpCas9	negative selection	4849031
52315059	52315081	14	-	27760321	HT29	viability after 7 days	ACTGCCCATAGTCCAGCAGCGG	PTGER2	ENSG00000125384	0.5929404440359265	[702,548]	[1284,1391,980]	8	hSpCas9	negative selection	4849032
52314812	52314834	14	+	27760321	HT29	viability after 25 days	GGTACTGGCTTCGTACGCGCGG	PTGER2	ENSG00000125384	0.16245002322672508	[698,545]	[772,853,757]	1	hSpCas9	negative selection	4932491
52314866	52314888	14	-	27760321	HT29	viability after 25 days	AGCGAAGTAGGTGCACGCGCGG	PTGER2	ENSG00000125384	0.16507818154224774	[522,407]	[550,551,698]	1	hSpCas9	negative selection	4932492
52314913	52314935	14	-	27760321	HT29	viability after 25 days	GCGAAGAGCATGAGCATCGTGG	PTGER2	ENSG00000125384	1.0021487937481024	[369,288]	[709,588,989]	9	hSpCas9	negative selection	4932493
52314944	52314966	14	+	27760321	HT29	viability after 25 days	GGAGCGCTACCTCTCGATCGGG	PTGER2	ENSG00000125384	0.228859335342863	[520,406]	[519,614,747]	2	hSpCas9	negative selection	4932494
52315059	52315081	14	-	27760321	HT29	viability after 25 days	ACTGCCCATAGTCCAGCAGCGG	PTGER2	ENSG00000125384	0.8213688638700942	[702,548]	[781,1422,1656]	8	hSpCas9	negative selection	4932495
52314812	52314834	14	+	27760321	HT29	viability after 22 days	GGTACTGGCTTCGTACGCGCGG	PTGER2	ENSG00000125384	0.3979342426763184	[698,545]	[1089,1002,745]	4	hSpCas9	negative selection	5015954
52314866	52314888	14	-	27760321	HT29	viability after 22 days	AGCGAAGTAGGTGCACGCGCGG	PTGER2	ENSG00000125384	0.31760420813341095	[522,407]	[616,762,632]	3	hSpCas9	negative selection	5015955
52314913	52314935	14	-	27760321	HT29	viability after 22 days	GCGAAGAGCATGAGCATCGTGG	PTGER2	ENSG00000125384	0.3772550845397169	[369,288]	[756,251,467]	4	hSpCas9	negative selection	5015956
52314944	52314966	14	+	27760321	HT29	viability after 22 days	GGAGCGCTACCTCTCGATCGGG	PTGER2	ENSG00000125384	0.31436040057980436	[520,406]	[719,576,702]	3	hSpCas9	negative selection	5015957
52315059	52315081	14	-	27760321	HT29	viability after 22 days	ACTGCCCATAGTCCAGCAGCGG	PTGER2	ENSG00000125384	0.7623699363450027	[702,548]	[1185,1262,1234]	8	hSpCas9	negative selection	5015958
52314812	52314834	14	+	27760321	HT29	viability after 19 days	GGTACTGGCTTCGTACGCGCGG	PTGER2	ENSG00000125384	0.3472730544953364	[698,545]	[820,987,898]	3	hSpCas9	negative selection	5099417
52314866	52314888	14	-	27760321	HT29	viability after 19 days	AGCGAAGTAGGTGCACGCGCGG	PTGER2	ENSG00000125384	0.17088974930996026	[522,407]	[801,316,695]	1	hSpCas9	negative selection	5099418
52314913	52314935	14	-	27760321	HT29	viability after 19 days	GCGAAGAGCATGAGCATCGTGG	PTGER2	ENSG00000125384	1.0134481460057685	[369,288]	[994,621,691]	9	hSpCas9	negative selection	5099419
52314944	52314966	14	+	27760321	HT29	viability after 19 days	GGAGCGCTACCTCTCGATCGGG	PTGER2	ENSG00000125384	0.26595959753747084	[520,406]	[654,656,604]	2	hSpCas9	negative selection	5099420
52315059	52315081	14	-	27760321	HT29	viability after 19 days	ACTGCCCATAGTCCAGCAGCGG	PTGER2	ENSG00000125384	0.6262156832390728	[702,548]	[1220,1115,993]	6	hSpCas9	negative selection	5099421
52314812	52314834	14	+	27760321	HT29	viability after 16 days	GGTACTGGCTTCGTACGCGCGG	PTGER2	ENSG00000125384	0.28531615891189754	[698,545]	[721,1165,637]	3	hSpCas9	negative selection	5182880
52314866	52314888	14	-	27760321	HT29	viability after 16 days	AGCGAAGTAGGTGCACGCGCGG	PTGER2	ENSG00000125384	-0.21260159046288213	[522,407]	[444,594,303]	-2	hSpCas9	negative selection	5182881
52314913	52314935	14	-	27760321	HT29	viability after 16 days	GCGAAGAGCATGAGCATCGTGG	PTGER2	ENSG00000125384	0.6570663028329149	[369,288]	[513,525,698]	7	hSpCas9	negative selection	5182882
52314944	52314966	14	+	27760321	HT29	viability after 16 days	GGAGCGCTACCTCTCGATCGGG	PTGER2	ENSG00000125384	0.43510280943764984	[520,406]	[517,671,898]	5	hSpCas9	negative selection	5182883
52315059	52315081	14	-	27760321	HT29	viability after 16 days	ACTGCCCATAGTCCAGCAGCGG	PTGER2	ENSG00000125384	0.8767869679673574	[702,548]	[1232,1521,1091]	9	hSpCas9	negative selection	5182884
52314812	52314834	14	+	27760321	HT29	viability after 13 days	GGTACTGGCTTCGTACGCGCGG	PTGER2	ENSG00000125384	0.029830750294713715	[698,545]	[555,864,787]	0	hSpCas9	negative selection	5266343
52314866	52314888	14	-	27760321	HT29	viability after 13 days	AGCGAAGTAGGTGCACGCGCGG	PTGER2	ENSG00000125384	0.11466119529696817	[522,407]	[675,633,451]	1	hSpCas9	negative selection	5266344
52314913	52314935	14	-	27760321	HT29	viability after 13 days	GCGAAGAGCATGAGCATCGTGG	PTGER2	ENSG00000125384	0.5039749158234823	[369,288]	[375,663,583]	6	hSpCas9	negative selection	5266345
52314944	52314966	14	+	27760321	HT29	viability after 13 days	GGAGCGCTACCTCTCGATCGGG	PTGER2	ENSG00000125384	0.09443405480406958	[520,406]	[607,557,558]	1	hSpCas9	negative selection	5266346
52315059	52315081	14	-	27760321	HT29	viability after 13 days	ACTGCCCATAGTCCAGCAGCGG	PTGER2	ENSG00000125384	0.6792210239886212	[702,548]	[1158,1275,1059]	8	hSpCas9	negative selection	5266347
52314812	52314834	14	+	27760321	HT29	viability after 10 days	GGTACTGGCTTCGTACGCGCGG	PTGER2	ENSG00000125384	0.06670134392762006	[698,545]	[881,963,604]	0	hSpCas9	negative selection	5349806
52314866	52314888	14	-	27760321	HT29	viability after 10 days	AGCGAAGTAGGTGCACGCGCGG	PTGER2	ENSG00000125384	-0.06651992068307616	[522,407]	[595,698,377]	-1	hSpCas9	negative selection	5349807
52314913	52314935	14	-	27760321	HT29	viability after 10 days	GCGAAGAGCATGAGCATCGTGG	PTGER2	ENSG00000125384	0.3252961506013423	[369,288]	[721,315,502]	4	hSpCas9	negative selection	5349808
52314944	52314966	14	+	27760321	HT29	viability after 10 days	GGAGCGCTACCTCTCGATCGGG	PTGER2	ENSG00000125384	0.014357394883215913	[520,406]	[612,484,652]	0	hSpCas9	negative selection	5349809
52315059	52315081	14	-	27760321	HT29	viability after 10 days	ACTGCCCATAGTCCAGCAGCGG	PTGER2	ENSG00000125384	0.501245389528238	[702,548]	[1141,1233,949]	6	hSpCas9	negative selection	5349810
52314812	52314834	14	+	27760321	MOLM13	viability	GGTACTGGCTTCGTACGCGCGG	PTGER2	ENSG00000125384	1.535317648024267	[732,698]	[903,1400]	9	hSpCas9	negative selection	5433269
52314866	52314888	14	-	27760321	MOLM13	viability	AGCGAAGTAGGTGCACGCGCGG	PTGER2	ENSG00000125384	-0.11433820009277118	[652,522]	[254,346]	0	hSpCas9	negative selection	5433270
52314913	52314935	14	-	27760321	MOLM13	viability	GCGAAGAGCATGAGCATCGTGG	PTGER2	ENSG00000125384	0.30682631442555947	[523,369]	[125,463]	2	hSpCas9	negative selection	5433271
52314944	52314966	14	+	27760321	MOLM13	viability	GGAGCGCTACCTCTCGATCGGG	PTGER2	ENSG00000125384	0.1960660797043705	[600,520]	[372,351]	1	hSpCas9	negative selection	5433272
52315059	52315081	14	-	27760321	MOLM13	viability	ACTGCCCATAGTCCAGCAGCGG	PTGER2	ENSG00000125384	1.1613429844237473	[899,702]	[1346,712]	7	hSpCas9	negative selection	5433273
52314369	52314392	14	+	27661255	K562	viability	GGCGCGCGGCGGGAGACCCAGGG	PTGER2	ENSG00000125384	-0.38779182328685535	[548,692]	[457,308]	-7	dCas9-KRAB	negative selection	5505090
52314691	52314714	14	+	27661255	K562	viability	GCCGCTGGCGGGGGGACGTGGGG	PTGER2	ENSG00000125384	0.342967942109791	[239,386]	[335,296]	9	dCas9-KRAB	negative selection	5505091
52314338	52314361	14	-	27661255	K562	viability	GCTCGGCTGCTGCATCCGAGCGG	PTGER2	ENSG00000125384	-0.0019014558817994909	[671,681]	[594,492]	0	dCas9-KRAB	negative selection	5505092
52314942	52314965	14	+	27260156	BXPC3	viability	CTGGAGCGCTACCTCTCGATCGG	PTGER2	ENSG00000125384	-0.08780470608105267	[376]	[308,363,383,439]	-2	hSpCas9	negative selection	5565408
52314953	52314976	14	-	27260156	BXPC3	viability	AGTAGGGGTGCCCGATCGAGAGG	PTGER2	ENSG00000125384	-0.35530868752211175	[322]	[226,352,197,274]	-7	hSpCas9	negative selection	5565409
52327235	52327258	14	+	27260156	BXPC3	viability	GAATGAAACCTCTTCCCGAAAGG	PTGER2	ENSG00000125384	0.4805114665638447	[203]	[247,265,312,378]	8	hSpCas9	negative selection	5565410
52327364	52327387	14	-	27260156	BXPC3	viability	TTAATGAAATCCGACAACAGAGG	PTGER2	ENSG00000125384	-0.36932859612303237	[308]	[209,247,295,249]	-7	hSpCas9	negative selection	5629667
52314634	52314657	14	-	27260156	BXPC3	viability	CACCCCGGCCGAGAACATGACGG	PTGER2	ENSG00000125384	0.15330658063702213	[325]	[376,394,340,401]	3	hSpCas9	negative selection	5629668
52314877	52314900	14	-	27260156	BXPC3	viability	GGTCATGGCGAAAGCGAAGTAGG	PTGER2	ENSG00000125384	0.16088765076611988	[37]	[33,46,48,48]	3	hSpCas9	negative selection	5629669
52314942	52314965	14	+	27260156	A673	viability	CTGGAGCGCTACCTCTCGATCGG	PTGER2	ENSG00000125384	-0.011308199921510165	[376]	[500,345,504,451]	0	hSpCas9	negative selection	5686659
52314953	52314976	14	-	27260156	A673	viability	AGTAGGGGTGCCCGATCGAGAGG	PTGER2	ENSG00000125384	-0.08401431065265297	[322]	[378,344,313,430]	-2	hSpCas9	negative selection	5686660
52327235	52327258	14	+	27260156	A673	viability	GAATGAAACCTCTTCCCGAAAGG	PTGER2	ENSG00000125384	0.5810527036455507	[203]	[408,381,282,397]	9	hSpCas9	negative selection	5686661
52327364	52327387	14	-	27260156	A673	viability	TTAATGAAATCCGACAACAGAGG	PTGER2	ENSG00000125384	-0.4092769115345729	[308]	[288,226,265,340]	-7	hSpCas9	negative selection	5750918
52314634	52314657	14	-	27260156	A673	viability	CACCCCGGCCGAGAACATGACGG	PTGER2	ENSG00000125384	0.24234876984300763	[325]	[508,432,472,440]	6	hSpCas9	negative selection	5750919
52314877	52314900	14	-	27260156	A673	viability	GGTCATGGCGAAAGCGAAGTAGG	PTGER2	ENSG00000125384	0.4121696791742382	[37]	[80,33,50,80]	8	hSpCas9	negative selection	5750920
52314942	52314965	14	+	27260156	A375	viability	CTGGAGCGCTACCTCTCGATCGG	PTGER2	ENSG00000125384	-0.06147632893724808	[376]	[474,523,401,312]	-1	hSpCas9	negative selection	5807910
52314953	52314976	14	-	27260156	A375	viability	AGTAGGGGTGCCCGATCGAGAGG	PTGER2	ENSG00000125384	-0.036359104932163655	[322]	[386,415,223,440]	0	hSpCas9	negative selection	5807911
52327235	52327258	14	+	27260156	A375	viability	GAATGAAACCTCTTCCCGAAAGG	PTGER2	ENSG00000125384	0.7686623940798061	[203]	[446,461,275,440]	9	hSpCas9	negative selection	5807912
52327364	52327387	14	-	27260156	A375	viability	TTAATGAAATCCGACAACAGAGG	PTGER2	ENSG00000125384	0.08882131665924398	[308]	[394,419,423,308]	1	hSpCas9	negative selection	5872169
52314634	52314657	14	-	27260156	A375	viability	CACCCCGGCCGAGAACATGACGG	PTGER2	ENSG00000125384	0.2662451432803602	[325]	[443,476,411,494]	4	hSpCas9	negative selection	5872170
52314877	52314900	14	-	27260156	A375	viability	GGTCATGGCGAAAGCGAAGTAGG	PTGER2	ENSG00000125384	0.5751230806130332	[37]	[69,106,91,7]	8	hSpCas9	negative selection	5872171
52314942	52314965	14	+	27260156	COLO741	viability	CTGGAGCGCTACCTCTCGATCGG	PTGER2	ENSG00000125384	-0.18848895653072445	[376]	[492,315,460]	-4	hSpCas9	negative selection	5929161
52314953	52314976	14	-	27260156	COLO741	viability	AGTAGGGGTGCCCGATCGAGAGG	PTGER2	ENSG00000125384	-0.2188714094688753	[322]	[400,354,313]	-5	hSpCas9	negative selection	5929162
52327235	52327258	14	+	27260156	COLO741	viability	GAATGAAACCTCTTCCCGAAAGG	PTGER2	ENSG00000125384	0.3781579072009382	[203]	[388,351,282]	7	hSpCas9	negative selection	5929163
52327364	52327387	14	-	27260156	COLO741	viability	TTAATGAAATCCGACAACAGAGG	PTGER2	ENSG00000125384	-0.6238345729081309	[308]	[218,303,242]	-8	hSpCas9	negative selection	5993420
52314634	52314657	14	-	27260156	COLO741	viability	CACCCCGGCCGAGAACATGACGG	PTGER2	ENSG00000125384	0.06971899169775697	[325]	[544,456,325]	1	hSpCas9	negative selection	5993421
52314877	52314900	14	-	27260156	COLO741	viability	GGTCATGGCGAAAGCGAAGTAGG	PTGER2	ENSG00000125384	-0.1379966323587256	[37]	[49,41,40]	-3	hSpCas9	negative selection	5993422
52314942	52314965	14	+	27260156	CAL120	viability	CTGGAGCGCTACCTCTCGATCGG	PTGER2	ENSG00000125384	-0.10763827172902235	[376]	[434,380,488]	-1	hSpCas9	negative selection	6050412
52314953	52314976	14	-	27260156	CAL120	viability	AGTAGGGGTGCCCGATCGAGAGG	PTGER2	ENSG00000125384	-0.49463420839558825	[322]	[102,312,409]	-6	hSpCas9	negative selection	6050413
52327235	52327258	14	+	27260156	CAL120	viability	GAATGAAACCTCTTCCCGAAAGG	PTGER2	ENSG00000125384	0.6047071155742811	[203]	[469,338,361]	8	hSpCas9	negative selection	6050414
52327364	52327387	14	-	27260156	CAL120	viability	TTAATGAAATCCGACAACAGAGG	PTGER2	ENSG00000125384	-0.13349398456574524	[308]	[425,352,284]	-2	hSpCas9	negative selection	6114671
52314634	52314657	14	-	27260156	CAL120	viability	CACCCCGGCCGAGAACATGACGG	PTGER2	ENSG00000125384	-0.14931752068984094	[325]	[389,297,411]	-2	hSpCas9	negative selection	6114672
52314877	52314900	14	-	27260156	CAL120	viability	GGTCATGGCGAAAGCGAAGTAGG	PTGER2	ENSG00000125384	-0.69369143241589	[37]	[15,56,12]	-7	hSpCas9	negative selection	6114673
52314942	52314965	14	+	27260156	CADOES1	viability	CTGGAGCGCTACCTCTCGATCGG	PTGER2	ENSG00000125384	-0.02824131904856908	[376]	[311,265,331,469]	0	hSpCas9	negative selection	6171663
52314953	52314976	14	-	27260156	CADOES1	viability	AGTAGGGGTGCCCGATCGAGAGG	PTGER2	ENSG00000125384	-0.30672724503866433	[322]	[249,256,259,202]	-5	hSpCas9	negative selection	6171664
52327235	52327258	14	+	27260156	CADOES1	viability	GAATGAAACCTCTTCCCGAAAGG	PTGER2	ENSG00000125384	0.9192788987196849	[203]	[268,437,309,420]	9	hSpCas9	negative selection	6171665
52327364	52327387	14	-	27260156	CADOES1	viability	TTAATGAAATCCGACAACAGAGG	PTGER2	ENSG00000125384	-0.6157857066714787	[308]	[237,206,119,184]	-8	hSpCas9	negative selection	6235922
52314634	52314657	14	-	27260156	CADOES1	viability	CACCCCGGCCGAGAACATGACGG	PTGER2	ENSG00000125384	0.2529685346027362	[325]	[231,461,409,340]	4	hSpCas9	negative selection	6235923
52314877	52314900	14	-	27260156	CADOES1	viability	GGTCATGGCGAAAGCGAAGTAGG	PTGER2	ENSG00000125384	-0.5066000721004817	[37]	[12,36,38,9]	-7	hSpCas9	negative selection	6235924
52314942	52314965	14	+	27260156	EWS502	viability	CTGGAGCGCTACCTCTCGATCGG	PTGER2	ENSG00000125384	-0.2089622472738621	[376]	[331,395,330,318]	-4	hSpCas9	negative selection	6292914
52314953	52314976	14	-	27260156	EWS502	viability	AGTAGGGGTGCCCGATCGAGAGG	PTGER2	ENSG00000125384	-0.5560046818004466	[322]	[171,290,254,215]	-7	hSpCas9	negative selection	6292915
52327235	52327258	14	+	27260156	EWS502	viability	GAATGAAACCTCTTCCCGAAAGG	PTGER2	ENSG00000125384	0.5665509504644973	[203]	[267,335,456,217]	8	hSpCas9	negative selection	6292916
52327364	52327387	14	-	27260156	EWS502	viability	TTAATGAAATCCGACAACAGAGG	PTGER2	ENSG00000125384	-0.19548363855542972	[308]	[282,211,262,394]	-3	hSpCas9	negative selection	6357173
52314634	52314657	14	-	27260156	EWS502	viability	CACCCCGGCCGAGAACATGACGG	PTGER2	ENSG00000125384	0.24494067520308999	[325]	[399,407,522,298]	4	hSpCas9	negative selection	6357174
52314877	52314900	14	-	27260156	EWS502	viability	GGTCATGGCGAAAGCGAAGTAGG	PTGER2	ENSG00000125384	-0.41801360569008317	[37]	[11,51,37,18]	-6	hSpCas9	negative selection	6357175
52314942	52314965	14	+	27260156	EW8	viability	CTGGAGCGCTACCTCTCGATCGG	PTGER2	ENSG00000125384	-0.1181408321645539	[376]	[197,343,312,255]	-2	hSpCas9	negative selection	6414165
52314953	52314976	14	-	27260156	EW8	viability	AGTAGGGGTGCCCGATCGAGAGG	PTGER2	ENSG00000125384	-0.4944656444945187	[322]	[169,159,201,205]	-7	hSpCas9	negative selection	6414166
52327235	52327258	14	+	27260156	EW8	viability	GAATGAAACCTCTTCCCGAAAGG	PTGER2	ENSG00000125384	0.11871706395537007	[203]	[217,210,131,168]	2	hSpCas9	negative selection	6414167
52327364	52327387	14	-	27260156	EW8	viability	TTAATGAAATCCGACAACAGAGG	PTGER2	ENSG00000125384	-0.3075134174810811	[308]	[124,186,207,278]	-5	hSpCas9	negative selection	6478424
52314634	52314657	14	-	27260156	EW8	viability	CACCCCGGCCGAGAACATGACGG	PTGER2	ENSG00000125384	0.39545088168914	[325]	[449,323,169,485]	7	hSpCas9	negative selection	6478425
52314877	52314900	14	-	27260156	EW8	viability	GGTCATGGCGAAAGCGAAGTAGG	PTGER2	ENSG00000125384	0.7663944628858648	[37]	[117,27,55,13]	9	hSpCas9	negative selection	6478426
52314942	52314965	14	+	27260156	CORL105	viability	CTGGAGCGCTACCTCTCGATCGG	PTGER2	ENSG00000125384	0.21025990804213557	[376]	[413,671,516,433]	4	hSpCas9	negative selection	6535416
52314953	52314976	14	-	27260156	CORL105	viability	AGTAGGGGTGCCCGATCGAGAGG	PTGER2	ENSG00000125384	-0.40283947325056124	[322]	[378,286,207,260]	-6	hSpCas9	negative selection	6535417
52327235	52327258	14	+	27260156	CORL105	viability	GAATGAAACCTCTTCCCGAAAGG	PTGER2	ENSG00000125384	0.34225996275369797	[203]	[363,310,307,230]	6	hSpCas9	negative selection	6535418
52327364	52327387	14	-	27260156	CORL105	viability	TTAATGAAATCCGACAACAGAGG	PTGER2	ENSG00000125384	-0.35391316798386274	[308]	[259,279,268,319]	-6	hSpCas9	negative selection	6599675
52314634	52314657	14	-	27260156	CORL105	viability	CACCCCGGCCGAGAACATGACGG	PTGER2	ENSG00000125384	0.5274866616401025	[325]	[533,450,642,587]	8	hSpCas9	negative selection	6599676
52314877	52314900	14	-	27260156	CORL105	viability	GGTCATGGCGAAAGCGAAGTAGG	PTGER2	ENSG00000125384	0.16483240420368794	[37]	[93,58,30,13]	3	hSpCas9	negative selection	6599677
52314942	52314965	14	+	27260156	HS294T	viability	CTGGAGCGCTACCTCTCGATCGG	PTGER2	ENSG00000125384	0.16868295335349656	[376]	[180,120,181,171]	2	hSpCas9	negative selection	6656667
52314953	52314976	14	-	27260156	HS294T	viability	AGTAGGGGTGCCCGATCGAGAGG	PTGER2	ENSG00000125384	-0.7084872108179013	[322]	[46,73,82,109]	-7	hSpCas9	negative selection	6656668
52327235	52327258	14	+	27260156	HS294T	viability	GAATGAAACCTCTTCCCGAAAGG	PTGER2	ENSG00000125384	1.1056124265144716	[203]	[136,51,249,261]	9	hSpCas9	negative selection	6656669
52327364	52327387	14	-	27260156	HS294T	viability	TTAATGAAATCCGACAACAGAGG	PTGER2	ENSG00000125384	-0.9413635452929037	[308]	[50,48,78,72]	-8	hSpCas9	negative selection	6720926
52314634	52314657	14	-	27260156	HS294T	viability	CACCCCGGCCGAGAACATGACGG	PTGER2	ENSG00000125384	0.10752059304167394	[325]	[124,101,141,183]	1	hSpCas9	negative selection	6720927
52314877	52314900	14	-	27260156	HS294T	viability	GGTCATGGCGAAAGCGAAGTAGG	PTGER2	ENSG00000125384	0.5523424904278644	[37]	[46,12,6,15]	7	hSpCas9	negative selection	6720928
52314942	52314965	14	+	27260156	HCC44	viability	CTGGAGCGCTACCTCTCGATCGG	PTGER2	ENSG00000125384	-0.13130493189067738	[376]	[374,415,446,322]	-2	hSpCas9	negative selection	6777918
52314953	52314976	14	-	27260156	HCC44	viability	AGTAGGGGTGCCCGATCGAGAGG	PTGER2	ENSG00000125384	-0.7953699803229805	[322]	[421,158,178,104]	-8	hSpCas9	negative selection	6777919
52327235	52327258	14	+	27260156	HCC44	viability	GAATGAAACCTCTTCCCGAAAGG	PTGER2	ENSG00000125384	0.747691878793804	[203]	[376,238,507,460]	9	hSpCas9	negative selection	6777920
52327364	52327387	14	-	27260156	HCC44	viability	TTAATGAAATCCGACAACAGAGG	PTGER2	ENSG00000125384	-0.5355561149758263	[308]	[268,248,225,217]	-7	hSpCas9	negative selection	6842177
52314634	52314657	14	-	27260156	HCC44	viability	CACCCCGGCCGAGAACATGACGG	PTGER2	ENSG00000125384	0.339488753168102	[325]	[664,305,479,454]	5	hSpCas9	negative selection	6842178
52314877	52314900	14	-	27260156	HCC44	viability	GGTCATGGCGAAAGCGAAGTAGG	PTGER2	ENSG00000125384	0.12849259926526324	[37]	[26,87,47,17]	2	hSpCas9	negative selection	6842179
52314942	52314965	14	+	27260156	G402	viability	CTGGAGCGCTACCTCTCGATCGG	PTGER2	ENSG00000125384	-0.17912252098864218	[376]	[328,248,611,412]	-2	hSpCas9	negative selection	6899169
52314953	52314976	14	-	27260156	G402	viability	AGTAGGGGTGCCCGATCGAGAGG	PTGER2	ENSG00000125384	0.08128873599864972	[322]	[326,356,277,674]	1	hSpCas9	negative selection	6899170
52327235	52327258	14	+	27260156	G402	viability	GAATGAAACCTCTTCCCGAAAGG	PTGER2	ENSG00000125384	1.1609574439714714	[203]	[365,188,695,906]	9	hSpCas9	negative selection	6899171
52327364	52327387	14	-	27260156	G402	viability	TTAATGAAATCCGACAACAGAGG	PTGER2	ENSG00000125384	-0.5715490664514831	[308]	[391,172,355,114]	-6	hSpCas9	negative selection	6963428
52314634	52314657	14	-	27260156	G402	viability	CACCCCGGCCGAGAACATGACGG	PTGER2	ENSG00000125384	0.5046169861444882	[325]	[494,954,339,481]	6	hSpCas9	negative selection	6963429
52314877	52314900	14	-	27260156	G402	viability	GGTCATGGCGAAAGCGAAGTAGG	PTGER2	ENSG00000125384	-2.111700661764253	[37]	[3,3,11,20]	-9	hSpCas9	negative selection	6963430
52314942	52314965	14	+	27260156	L33	viability	CTGGAGCGCTACCTCTCGATCGG	PTGER2	ENSG00000125384	-0.22161301948617634	[376]	[261,124,223,370]	-5	hSpCas9	negative selection	7020420
52314953	52314976	14	-	27260156	L33	viability	AGTAGGGGTGCCCGATCGAGAGG	PTGER2	ENSG00000125384	-0.14370046674027914	[322]	[283,79,237,311]	-3	hSpCas9	negative selection	7020421
52327235	52327258	14	+	27260156	L33	viability	GAATGAAACCTCTTCCCGAAAGG	PTGER2	ENSG00000125384	0.6469936066506273	[203]	[314,99,262,300]	9	hSpCas9	negative selection	7020422
52327364	52327387	14	-	27260156	L33	viability	TTAATGAAATCCGACAACAGAGG	PTGER2	ENSG00000125384	-0.2826274282535852	[308]	[277,87,152,278]	-6	hSpCas9	negative selection	7084679
52314634	52314657	14	-	27260156	L33	viability	CACCCCGGCCGAGAACATGACGG	PTGER2	ENSG00000125384	0.4592793118652827	[325]	[351,223,300,417]	8	hSpCas9	negative selection	7084680
52314877	52314900	14	-	27260156	L33	viability	GGTCATGGCGAAAGCGAAGTAGG	PTGER2	ENSG00000125384	-0.17508800296462645	[37]	[20,17,21,34]	-4	hSpCas9	negative selection	7084681
52314942	52314965	14	+	27260156	K562	viability	CTGGAGCGCTACCTCTCGATCGG	PTGER2	ENSG00000125384	0.10336979036068406	[376]	[317,433,422,271]	1	hSpCas9	negative selection	7141671
52314953	52314976	14	-	27260156	K562	viability	AGTAGGGGTGCCCGATCGAGAGG	PTGER2	ENSG00000125384	-0.7449428968570583	[322]	[132,126,331,94]	-7	hSpCas9	negative selection	7141672
52327235	52327258	14	+	27260156	K562	viability	GAATGAAACCTCTTCCCGAAAGG	PTGER2	ENSG00000125384	0.14326784226611422	[203]	[415,42,249,109]	1	hSpCas9	negative selection	7141673
52327364	52327387	14	-	27260156	K562	viability	TTAATGAAATCCGACAACAGAGG	PTGER2	ENSG00000125384	-0.6685576019835588	[308]	[113,109,319,140]	-7	hSpCas9	negative selection	7205930
52314634	52314657	14	-	27260156	K562	viability	CACCCCGGCCGAGAACATGACGG	PTGER2	ENSG00000125384	1.9167406680977848	[325]	[2518,370,748,834]	9	hSpCas9	negative selection	7205931
52314877	52314900	14	-	27260156	K562	viability	GGTCATGGCGAAAGCGAAGTAGG	PTGER2	ENSG00000125384	0.32757950696286064	[37]	[39,67,26,35]	4	hSpCas9	negative selection	7205932
52314942	52314965	14	+	27260156	HT29	viability	CTGGAGCGCTACCTCTCGATCGG	PTGER2	ENSG00000125384	-0.1670787728336422	[376]	[457,427,356,393]	-3	hSpCas9	negative selection	7262922
52314953	52314976	14	-	27260156	HT29	viability	AGTAGGGGTGCCCGATCGAGAGG	PTGER2	ENSG00000125384	-0.30816098336598974	[322]	[277,389,405,208]	-5	hSpCas9	negative selection	7262923
52327235	52327258	14	+	27260156	HT29	viability	GAATGAAACCTCTTCCCGAAAGG	PTGER2	ENSG00000125384	0.47069191445050806	[203]	[339,436,206,389]	8	hSpCas9	negative selection	7262924
52327364	52327387	14	-	27260156	HT29	viability	TTAATGAAATCCGACAACAGAGG	PTGER2	ENSG00000125384	-0.14255525839343697	[308]	[323,493,242,312]	-3	hSpCas9	negative selection	7327181
52314634	52314657	14	-	27260156	HT29	viability	CACCCCGGCCGAGAACATGACGG	PTGER2	ENSG00000125384	0.27546712662001105	[325]	[544,544,411,429]	5	hSpCas9	negative selection	7327182
52314877	52314900	14	-	27260156	HT29	viability	GGTCATGGCGAAAGCGAAGTAGG	PTGER2	ENSG00000125384	-0.2503871097014949	[37]	[8,51,72,21]	-5	hSpCas9	negative selection	7327183
52314942	52314965	14	+	27260156	MHHES1	viability	CTGGAGCGCTACCTCTCGATCGG	PTGER2	ENSG00000125384	0.36464472053463287	[376]	[495,837,512,387]	6	hSpCas9	negative selection	7384173
52314953	52314976	14	-	27260156	MHHES1	viability	AGTAGGGGTGCCCGATCGAGAGG	PTGER2	ENSG00000125384	-0.42643273466045994	[322]	[213,169,469,218]	-7	hSpCas9	negative selection	7384174
52327235	52327258	14	+	27260156	MHHES1	viability	GAATGAAACCTCTTCCCGAAAGG	PTGER2	ENSG00000125384	0.22002672055055295	[203]	[228,234,321,269]	4	hSpCas9	negative selection	7384175
52327364	52327387	14	-	27260156	MHHES1	viability	TTAATGAAATCCGACAACAGAGG	PTGER2	ENSG00000125384	-0.22831130657957632	[308]	[108,394,382,284]	-4	hSpCas9	negative selection	7448432
52314634	52314657	14	-	27260156	MHHES1	viability	CACCCCGGCCGAGAACATGACGG	PTGER2	ENSG00000125384	0.2613185784353341	[325]	[315,545,449,434]	5	hSpCas9	negative selection	7448433
52314877	52314900	14	-	27260156	MHHES1	viability	GGTCATGGCGAAAGCGAAGTAGG	PTGER2	ENSG00000125384	0.04959725000291604	[37]	[29,103,5,40]	0	hSpCas9	negative selection	7448434
52314942	52314965	14	+	27260156	MEWO	viability	CTGGAGCGCTACCTCTCGATCGG	PTGER2	ENSG00000125384	-0.10483953004238328	[376]	[272,374,324]	-2	hSpCas9	negative selection	7505424
52314953	52314976	14	-	27260156	MEWO	viability	AGTAGGGGTGCCCGATCGAGAGG	PTGER2	ENSG00000125384	-0.2518129496804993	[322]	[230,231,293]	-5	hSpCas9	negative selection	7505425
52327235	52327258	14	+	27260156	MEWO	viability	GAATGAAACCTCTTCCCGAAAGG	PTGER2	ENSG00000125384	0.2998115399905228	[203]	[347,166,211]	6	hSpCas9	negative selection	7505426
52327364	52327387	14	-	27260156	MEWO	viability	TTAATGAAATCCGACAACAGAGG	PTGER2	ENSG00000125384	-0.24433263885151146	[308]	[292,157,290]	-5	hSpCas9	negative selection	7569683
52314634	52314657	14	-	27260156	MEWO	viability	CACCCCGGCCGAGAACATGACGG	PTGER2	ENSG00000125384	0.2109828524847847	[325]	[457,214,406]	4	hSpCas9	negative selection	7569684
52314877	52314900	14	-	27260156	MEWO	viability	GGTCATGGCGAAAGCGAAGTAGG	PTGER2	ENSG00000125384	0.41874095727064065	[37]	[34,74,29]	8	hSpCas9	negative selection	7569685
52314942	52314965	14	+	27260156	LNCAPCLONEFGC	viability	CTGGAGCGCTACCTCTCGATCGG	PTGER2	ENSG00000125384	0.10707812252153323	[376]	[318,324,449,392]	1	hSpCas9	negative selection	7626675
52314953	52314976	14	-	27260156	LNCAPCLONEFGC	viability	AGTAGGGGTGCCCGATCGAGAGG	PTGER2	ENSG00000125384	-0.47731318690756563	[322]	[157,204,257,227]	-6	hSpCas9	negative selection	7626676
52327235	52327258	14	+	27260156	LNCAPCLONEFGC	viability	GAATGAAACCTCTTCCCGAAAGG	PTGER2	ENSG00000125384	0.35470653036775757	[203]	[231,247,179,275]	5	hSpCas9	negative selection	7626677
52327364	52327387	14	-	27260156	LNCAPCLONEFGC	viability	TTAATGAAATCCGACAACAGAGG	PTGER2	ENSG00000125384	-0.2833327018441262	[308]	[303,212,212,186]	-4	hSpCas9	negative selection	7690934
52314634	52314657	14	-	27260156	LNCAPCLONEFGC	viability	CACCCCGGCCGAGAACATGACGG	PTGER2	ENSG00000125384	0.3195585557918512	[325]	[379,380,362,347]	5	hSpCas9	negative selection	7690935
52314877	52314900	14	-	27260156	LNCAPCLONEFGC	viability	GGTCATGGCGAAAGCGAAGTAGG	PTGER2	ENSG00000125384	-0.41371359916601236	[37]	[41,20,9,27]	-6	hSpCas9	negative selection	7690936
52314942	52314965	14	+	27260156	PANC0327	viability	CTGGAGCGCTACCTCTCGATCGG	PTGER2	ENSG00000125384	0.504731479334151	[376]	[283,273,1091,261]	7	hSpCas9	negative selection	7747926
52314953	52314976	14	-	27260156	PANC0327	viability	AGTAGGGGTGCCCGATCGAGAGG	PTGER2	ENSG00000125384	-0.7640494806610852	[322]	[172,129,129,247]	-8	hSpCas9	negative selection	7747927
52327235	52327258	14	+	27260156	PANC0327	viability	GAATGAAACCTCTTCCCGAAAGG	PTGER2	ENSG00000125384	0.735437036329448	[203]	[255,226,495,233]	9	hSpCas9	negative selection	7747928
52327364	52327387	14	-	27260156	PANC0327	viability	TTAATGAAATCCGACAACAGAGG	PTGER2	ENSG00000125384	-0.2653517366454219	[308]	[276,160,192,294]	-4	hSpCas9	negative selection	7812185
52314634	52314657	14	-	27260156	PANC0327	viability	CACCCCGGCCGAGAACATGACGG	PTGER2	ENSG00000125384	0.27143805676519206	[325]	[345,326,501,225]	4	hSpCas9	negative selection	7812186
52314877	52314900	14	-	27260156	PANC0327	viability	GGTCATGGCGAAAGCGAAGTAGG	PTGER2	ENSG00000125384	0.2643404388551982	[37]	[113,33,10,9]	4	hSpCas9	negative selection	7812187
52314942	52314965	14	+	27260156	NCIH2009	viability	CTGGAGCGCTACCTCTCGATCGG	PTGER2	ENSG00000125384	0.20268349798332896	[376]	[714,606,516]	2	hSpCas9	negative selection	7869177
52314953	52314976	14	-	27260156	NCIH2009	viability	AGTAGGGGTGCCCGATCGAGAGG	PTGER2	ENSG00000125384	-0.5490487879222506	[322]	[416,266,262]	-6	hSpCas9	negative selection	7869178
52327235	52327258	14	+	27260156	NCIH2009	viability	GAATGAAACCTCTTCCCGAAAGG	PTGER2	ENSG00000125384	0.5828293797568223	[203]	[389,353,529]	7	hSpCas9	negative selection	7869179
52327364	52327387	14	-	27260156	NCIH2009	viability	TTAATGAAATCCGACAACAGAGG	PTGER2	ENSG00000125384	-0.5881925721560624	[308]	[337,235,297]	-6	hSpCas9	negative selection	7933436
52314634	52314657	14	-	27260156	NCIH2009	viability	CACCCCGGCCGAGAACATGACGG	PTGER2	ENSG00000125384	0.3725235005968457	[325]	[824,396,595]	5	hSpCas9	negative selection	7933437
52314877	52314900	14	-	27260156	NCIH2009	viability	GGTCATGGCGAAAGCGAAGTAGG	PTGER2	ENSG00000125384	0.09153149710254205	[37]	[56,94,16]	1	hSpCas9	negative selection	7933438
52314942	52314965	14	+	27260156	NCIH1373	viability	CTGGAGCGCTACCTCTCGATCGG	PTGER2	ENSG00000125384	-0.504894850975919	[376]	[142,294,448,71]	-5	hSpCas9	negative selection	7990428
52314953	52314976	14	-	27260156	NCIH1373	viability	AGTAGGGGTGCCCGATCGAGAGG	PTGER2	ENSG00000125384	-0.4183579138086284	[322]	[188,423,188,65]	-4	hSpCas9	negative selection	7990429
52327235	52327258	14	+	27260156	NCIH1373	viability	GAATGAAACCTCTTCCCGAAAGG	PTGER2	ENSG00000125384	0.17997610900605876	[203]	[382,264,190,55]	1	hSpCas9	negative selection	7990430
52327364	52327387	14	-	27260156	NCIH1373	viability	TTAATGAAATCCGACAACAGAGG	PTGER2	ENSG00000125384	-0.371779198048363	[308]	[515,138,236,59]	-4	hSpCas9	negative selection	8054687
52314634	52314657	14	-	27260156	NCIH1373	viability	CACCCCGGCCGAGAACATGACGG	PTGER2	ENSG00000125384	0.41600104057273773	[325]	[483,362,514,158]	4	hSpCas9	negative selection	8054688
52314877	52314900	14	-	27260156	NCIH1373	viability	GGTCATGGCGAAAGCGAAGTAGG	PTGER2	ENSG00000125384	0.6030887376433895	[37]	[0,60,85,26]	6	hSpCas9	negative selection	8054689
52314942	52314965	14	+	27260156	PATU8902	viability	CTGGAGCGCTACCTCTCGATCGG	PTGER2	ENSG00000125384	0.24123885258507008	[376]	[451,549,658,833]	2	hSpCas9	negative selection	8111679
52314953	52314976	14	-	27260156	PATU8902	viability	AGTAGGGGTGCCCGATCGAGAGG	PTGER2	ENSG00000125384	-0.5598713182858944	[322]	[406,394,164,283]	-5	hSpCas9	negative selection	8111680
52327235	52327258	14	+	27260156	PATU8902	viability	GAATGAAACCTCTTCCCGAAAGG	PTGER2	ENSG00000125384	0.7007678930719803	[203]	[601,178,489,575]	7	hSpCas9	negative selection	8111681
52327364	52327387	14	-	27260156	PATU8902	viability	TTAATGAAATCCGACAACAGAGG	PTGER2	ENSG00000125384	-0.20097660241462756	[308]	[561,487,229,232]	-2	hSpCas9	negative selection	8175938
52314634	52314657	14	-	27260156	PATU8902	viability	CACCCCGGCCGAGAACATGACGG	PTGER2	ENSG00000125384	0.48343896474659614	[325]	[743,797,576,400]	5	hSpCas9	negative selection	8175939
52314877	52314900	14	-	27260156	PATU8902	viability	GGTCATGGCGAAAGCGAAGTAGG	PTGER2	ENSG00000125384	0.47028656182501516	[37]	[14,1,65,230]	5	hSpCas9	negative selection	8175940
52314942	52314965	14	+	27260156	PANC1	viability	CTGGAGCGCTACCTCTCGATCGG	PTGER2	ENSG00000125384	-0.08083449770530388	[376]	[247,632,176,239]	-1	hSpCas9	negative selection	8232930
52314953	52314976	14	-	27260156	PANC1	viability	AGTAGGGGTGCCCGATCGAGAGG	PTGER2	ENSG00000125384	-0.2479926920329366	[322]	[208,177,238,284]	-4	hSpCas9	negative selection	8232931
52327235	52327258	14	+	27260156	PANC1	viability	GAATGAAACCTCTTCCCGAAAGG	PTGER2	ENSG00000125384	0.49985059428919965	[203]	[289,298,272,150]	7	hSpCas9	negative selection	8232932
52327364	52327387	14	-	27260156	PANC1	viability	TTAATGAAATCCGACAACAGAGG	PTGER2	ENSG00000125384	-0.4094168883964875	[308]	[157,191,234,208]	-6	hSpCas9	negative selection	8297189
52314634	52314657	14	-	27260156	PANC1	viability	CACCCCGGCCGAGAACATGACGG	PTGER2	ENSG00000125384	-0.09766614267920992	[325]	[258,276,198,302]	-2	hSpCas9	negative selection	8297190
52314877	52314900	14	-	27260156	PANC1	viability	GGTCATGGCGAAAGCGAAGTAGG	PTGER2	ENSG00000125384	-0.47487538859240885	[37]	[37,9,2,36]	-6	hSpCas9	negative selection	8297191
52314942	52314965	14	+	27260156	PANC0813	viability	CTGGAGCGCTACCTCTCGATCGG	PTGER2	ENSG00000125384	-0.4775655208653001	[376]	[298,487,214,269]	-6	hSpCas9	negative selection	8354181
52314953	52314976	14	-	27260156	PANC0813	viability	AGTAGGGGTGCCCGATCGAGAGG	PTGER2	ENSG00000125384	-0.745248887998562	[322]	[242,384,126,154]	-8	hSpCas9	negative selection	8354182
52327235	52327258	14	+	27260156	PANC0813	viability	GAATGAAACCTCTTCCCGAAAGG	PTGER2	ENSG00000125384	0.7587197096645604	[203]	[412,429,327,447]	9	hSpCas9	negative selection	8354183
52327364	52327387	14	-	27260156	PANC0813	viability	TTAATGAAATCCGACAACAGAGG	PTGER2	ENSG00000125384	-0.0810099693641202	[308]	[254,311,429,365]	-1	hSpCas9	negative selection	8418440
52314634	52314657	14	-	27260156	PANC0813	viability	CACCCCGGCCGAGAACATGACGG	PTGER2	ENSG00000125384	0.38524703914906544	[325]	[670,617,462,275]	6	hSpCas9	negative selection	8418441
52314877	52314900	14	-	27260156	PANC0813	viability	GGTCATGGCGAAAGCGAAGTAGG	PTGER2	ENSG00000125384	0.4165045873664144	[37]	[42,86,53,52]	6	hSpCas9	negative selection	8418442
52314942	52314965	14	+	27260156	RDES	viability	CTGGAGCGCTACCTCTCGATCGG	PTGER2	ENSG00000125384	-0.2861900136990219	[376]	[335,278,360,462]	-5	hSpCas9	negative selection	8475432
52314953	52314976	14	-	27260156	RDES	viability	AGTAGGGGTGCCCGATCGAGAGG	PTGER2	ENSG00000125384	-0.6983871922537043	[322]	[183,228,191,326]	-8	hSpCas9	negative selection	8475433
52327235	52327258	14	+	27260156	RDES	viability	GAATGAAACCTCTTCCCGAAAGG	PTGER2	ENSG00000125384	0.5420920467576265	[203]	[248,463,326,319]	8	hSpCas9	negative selection	8475434
52327364	52327387	14	-	27260156	RDES	viability	TTAATGAAATCCGACAACAGAGG	PTGER2	ENSG00000125384	-0.39736205076790343	[308]	[209,287,285,303]	-6	hSpCas9	negative selection	8539691
52314634	52314657	14	-	27260156	RDES	viability	CACCCCGGCCGAGAACATGACGG	PTGER2	ENSG00000125384	0.13098804842454842	[325]	[299,282,593,512]	2	hSpCas9	negative selection	8539692
52314877	52314900	14	-	27260156	RDES	viability	GGTCATGGCGAAAGCGAAGTAGG	PTGER2	ENSG00000125384	0.057002723579338443	[37]	[23,46,55,60]	0	hSpCas9	negative selection	8539693
52314942	52314965	14	+	27260156	PC3	viability	CTGGAGCGCTACCTCTCGATCGG	PTGER2	ENSG00000125384	-0.1884919269273489	[376]	[261,274,518,329]	-4	hSpCas9	negative selection	8596683
52314953	52314976	14	-	27260156	PC3	viability	AGTAGGGGTGCCCGATCGAGAGG	PTGER2	ENSG00000125384	-0.4466891497804406	[322]	[117,257,403,262]	-7	hSpCas9	negative selection	8596684
52327235	52327258	14	+	27260156	PC3	viability	GAATGAAACCTCTTCCCGAAAGG	PTGER2	ENSG00000125384	0.684898598231319	[203]	[251,335,429,322]	9	hSpCas9	negative selection	8596685
52327364	52327387	14	-	27260156	PC3	viability	TTAATGAAATCCGACAACAGAGG	PTGER2	ENSG00000125384	-0.6980999883144172	[308]	[133,185,194,252]	-9	hSpCas9	negative selection	8660942
52314634	52314657	14	-	27260156	PC3	viability	CACCCCGGCCGAGAACATGACGG	PTGER2	ENSG00000125384	-0.18830391779969602	[325]	[143,199,564,389]	-4	hSpCas9	negative selection	8660943
52314877	52314900	14	-	27260156	PC3	viability	GGTCATGGCGAAAGCGAAGTAGG	PTGER2	ENSG00000125384	0.3956067403470187	[37]	[64,35,32,42]	8	hSpCas9	negative selection	8660944
52314942	52314965	14	+	27260156	PATU8988T	viability	CTGGAGCGCTACCTCTCGATCGG	PTGER2	ENSG00000125384	-0.08022703941214382	[376]	[252,606,237,302]	-1	hSpCas9	negative selection	8717934
52314953	52314976	14	-	27260156	PATU8988T	viability	AGTAGGGGTGCCCGATCGAGAGG	PTGER2	ENSG00000125384	-0.42331615676125023	[322]	[224,242,249,211]	-6	hSpCas9	negative selection	8717935
52327235	52327258	14	+	27260156	PATU8988T	viability	GAATGAAACCTCTTCCCGAAAGG	PTGER2	ENSG00000125384	0.7542095389225157	[203]	[393,516,236,188]	9	hSpCas9	negative selection	8717936
52327364	52327387	14	-	27260156	PATU8988T	viability	TTAATGAAATCCGACAACAGAGG	PTGER2	ENSG00000125384	-0.4467698775917879	[308]	[234,163,238,233]	-6	hSpCas9	negative selection	8782193
52314634	52314657	14	-	27260156	PATU8988T	viability	CACCCCGGCCGAGAACATGACGG	PTGER2	ENSG00000125384	0.4734405046058604	[325]	[362,587,310,508]	7	hSpCas9	negative selection	8782194
52314877	52314900	14	-	27260156	PATU8988T	viability	GGTCATGGCGAAAGCGAAGTAGG	PTGER2	ENSG00000125384	0.1328269830915234	[37]	[10,34,54,60]	2	hSpCas9	negative selection	8782195
52314942	52314965	14	+	27260156	T47D	viability	CTGGAGCGCTACCTCTCGATCGG	PTGER2	ENSG00000125384	-0.06790256660881694	[376]	[495,411,368,399]	-1	hSpCas9	negative selection	8839185
52314953	52314976	14	-	27260156	T47D	viability	AGTAGGGGTGCCCGATCGAGAGG	PTGER2	ENSG00000125384	-0.4075933636694402	[322]	[234,318,296,279]	-7	hSpCas9	negative selection	8839186
52327235	52327258	14	+	27260156	T47D	viability	GAATGAAACCTCTTCCCGAAAGG	PTGER2	ENSG00000125384	0.627272348983092	[203]	[376,310,404,379]	9	hSpCas9	negative selection	8839187
52327364	52327387	14	-	27260156	T47D	viability	TTAATGAAATCCGACAACAGAGG	PTGER2	ENSG00000125384	-0.4253780426959781	[308]	[311,239,294,225]	-7	hSpCas9	negative selection	8903444
52314634	52314657	14	-	27260156	T47D	viability	CACCCCGGCCGAGAACATGACGG	PTGER2	ENSG00000125384	0.12754000011414424	[325]	[507,343,403,409]	2	hSpCas9	negative selection	8903445
52314877	52314900	14	-	27260156	T47D	viability	GGTCATGGCGAAAGCGAAGTAGG	PTGER2	ENSG00000125384	0.19716216241826956	[37]	[40,40,39,82]	4	hSpCas9	negative selection	8903446
52314942	52314965	14	+	27260156	SU8686	viability	CTGGAGCGCTACCTCTCGATCGG	PTGER2	ENSG00000125384	-0.36584873218007735	[376]	[201,311,252,417]	-6	hSpCas9	negative selection	8960436
52314953	52314976	14	-	27260156	SU8686	viability	AGTAGGGGTGCCCGATCGAGAGG	PTGER2	ENSG00000125384	-0.37444694931586586	[322]	[239,186,235,347]	-6	hSpCas9	negative selection	8960437
52327235	52327258	14	+	27260156	SU8686	viability	GAATGAAACCTCTTCCCGAAAGG	PTGER2	ENSG00000125384	0.9344139798836377	[203]	[278,381,434,475]	9	hSpCas9	negative selection	8960438
52327364	52327387	14	-	27260156	SU8686	viability	TTAATGAAATCCGACAACAGAGG	PTGER2	ENSG00000125384	-0.6317645186665795	[308]	[186,209,149,248]	-7	hSpCas9	negative selection	9024695
52314634	52314657	14	-	27260156	SU8686	viability	CACCCCGGCCGAGAACATGACGG	PTGER2	ENSG00000125384	0.6173514517329374	[325]	[294,418,701,622]	8	hSpCas9	negative selection	9024696
52314877	52314900	14	-	27260156	SU8686	viability	GGTCATGGCGAAAGCGAAGTAGG	PTGER2	ENSG00000125384	0.040625038501819866	[37]	[42,21,26,68]	0	hSpCas9	negative selection	9024697
52314942	52314965	14	+	27260156	SKES1	viability	CTGGAGCGCTACCTCTCGATCGG	PTGER2	ENSG00000125384	-0.0014072614786483362	[376]	[504,315,423,275]	0	hSpCas9	negative selection	9081687
52314953	52314976	14	-	27260156	SKES1	viability	AGTAGGGGTGCCCGATCGAGAGG	PTGER2	ENSG00000125384	-0.9688857481628986	[322]	[203,148,136,169]	-9	hSpCas9	negative selection	9081688
52327235	52327258	14	+	27260156	SKES1	viability	GAATGAAACCTCTTCCCGAAAGG	PTGER2	ENSG00000125384	0.6332144060647328	[203]	[389,422,191,282]	9	hSpCas9	negative selection	9081689
52327364	52327387	14	-	27260156	SKES1	viability	TTAATGAAATCCGACAACAGAGG	PTGER2	ENSG00000125384	-0.31609197328870997	[308]	[202,305,296,188]	-6	hSpCas9	negative selection	9145946
52314634	52314657	14	-	27260156	SKES1	viability	CACCCCGGCCGAGAACATGACGG	PTGER2	ENSG00000125384	0.16060818683306766	[325]	[482,390,309,294]	3	hSpCas9	negative selection	9145947
52314877	52314900	14	-	27260156	SKES1	viability	GGTCATGGCGAAAGCGAAGTAGG	PTGER2	ENSG00000125384	0.5812562775084609	[37]	[43,24,71,76]	9	hSpCas9	negative selection	9145948
52314942	52314965	14	+	27260156	TOV112D	viability	CTGGAGCGCTACCTCTCGATCGG	PTGER2	ENSG00000125384	-0.295428169779505	[376]	[353,396,231,273]	-5	hSpCas9	negative selection	9202938
52314953	52314976	14	-	27260156	TOV112D	viability	AGTAGGGGTGCCCGATCGAGAGG	PTGER2	ENSG00000125384	-0.14673482511727431	[322]	[230,227,380,306]	-3	hSpCas9	negative selection	9202939
52327235	52327258	14	+	27260156	TOV112D	viability	GAATGAAACCTCTTCCCGAAAGG	PTGER2	ENSG00000125384	0.4480673413009728	[203]	[235,317,304,261]	8	hSpCas9	negative selection	9202940
52327364	52327387	14	-	27260156	TOV112D	viability	TTAATGAAATCCGACAACAGAGG	PTGER2	ENSG00000125384	-0.1657947823789251	[308]	[396,549,148,89]	-3	hSpCas9	negative selection	9267197
52314634	52314657	14	-	27260156	TOV112D	viability	CACCCCGGCCGAGAACATGACGG	PTGER2	ENSG00000125384	0.3521326444979559	[325]	[329,545,438,376]	6	hSpCas9	negative selection	9267198
52314877	52314900	14	-	27260156	TOV112D	viability	GGTCATGGCGAAAGCGAAGTAGG	PTGER2	ENSG00000125384	-0.015370907639653986	[37]	[52,66,34,4]	0	hSpCas9	negative selection	9267199
52314942	52314965	14	+	27260156	TC71	viability	CTGGAGCGCTACCTCTCGATCGG	PTGER2	ENSG00000125384	0.06845358104234164	[376]	[478,277,409,533]	1	hSpCas9	negative selection	9324189
52314953	52314976	14	-	27260156	TC71	viability	AGTAGGGGTGCCCGATCGAGAGG	PTGER2	ENSG00000125384	-0.1730648805257563	[322]	[258,270,366,331]	-4	hSpCas9	negative selection	9324190
52327235	52327258	14	+	27260156	TC71	viability	GAATGAAACCTCTTCCCGAAAGG	PTGER2	ENSG00000125384	0.4785566746915416	[203]	[342,330,230,315]	9	hSpCas9	negative selection	9324191
52327364	52327387	14	-	27260156	TC71	viability	TTAATGAAATCCGACAACAGAGG	PTGER2	ENSG00000125384	-0.437357039351876	[308]	[252,273,231,217]	-8	hSpCas9	negative selection	9388448
52314634	52314657	14	-	27260156	TC71	viability	CACCCCGGCCGAGAACATGACGG	PTGER2	ENSG00000125384	0.11922778158576652	[325]	[415,374,371,352]	3	hSpCas9	negative selection	9388449
52314877	52314900	14	-	27260156	TC71	viability	GGTCATGGCGAAAGCGAAGTAGG	PTGER2	ENSG00000125384	0.6229998870315283	[37]	[121,42,51,30]	9	hSpCas9	negative selection	9388450
52314942	52314965	14	+	27260156	TC32	viability	CTGGAGCGCTACCTCTCGATCGG	PTGER2	ENSG00000125384	-0.049442514396633275	[376]	[317,292,460,316]	-1	hSpCas9	negative selection	9445440
52314953	52314976	14	-	27260156	TC32	viability	AGTAGGGGTGCCCGATCGAGAGG	PTGER2	ENSG00000125384	-0.5629236553488705	[322]	[204,98,274,288]	-8	hSpCas9	negative selection	9445441
52327235	52327258	14	+	27260156	TC32	viability	GAATGAAACCTCTTCCCGAAAGG	PTGER2	ENSG00000125384	0.4056906349915078	[203]	[185,195,339,328]	7	hSpCas9	negative selection	9445442
52327364	52327387	14	-	27260156	TC32	viability	TTAATGAAATCCGACAACAGAGG	PTGER2	ENSG00000125384	-0.3876663087468034	[308]	[207,176,286,232]	-6	hSpCas9	negative selection	9509699
52314634	52314657	14	-	27260156	TC32	viability	CACCCCGGCCGAGAACATGACGG	PTGER2	ENSG00000125384	0.14839456008660562	[325]	[473,167,334,411]	2	hSpCas9	negative selection	9509700
52314877	52314900	14	-	27260156	TC32	viability	GGTCATGGCGAAAGCGAAGTAGG	PTGER2	ENSG00000125384	0.44407914236225565	[37]	[30,57,56,44]	7	hSpCas9	negative selection	9509701
52314572	52314595	14	-	27869803	HPAFII	viability after 27 days	GCGTCTCGCAGTCCTCAGACTGG	PTGER2	ENSG00000125384	0.2791277110727822	[283]	[142,212,NaN]	2	hSpCas9	negative selection	9551725
52314742	52314765	14	-	27869803	HPAFII	viability after 27 days	GGTCACCAGCACGTGGAACAAGG	PTGER2	ENSG00000125384	-0.8841529081924748	[329]	[57,123,NaN]	-6	hSpCas9	negative selection	9551726
52315105	52315128	14	+	27869803	HPAFII	viability after 27 days	GGTGCTTCATCCGGCACGGGCGG	PTGER2	ENSG00000125384	0.5543812333824851	[68]	[97,15,NaN]	4	hSpCas9	negative selection	9551727
52315216	52315239	14	+	27869803	HPAFII	viability after 27 days	TCCGCATGCACCGCCGAAGCCGG	PTGER2	ENSG00000125384	0.2804814339503956	[743]	[551,410,NaN]	2	hSpCas9	negative selection	9551728
52327235	52327258	14	+	27869803	HPAFII	viability after 27 days	GAATGAAACCTCTTCCCGAAAGG	PTGER2	ENSG00000125384	1.058504595229781	[177]	[207,183,NaN]	8	hSpCas9	negative selection	9551729
52327338	52327361	14	-	27869803	HPAFII	viability after 27 days	GAACGCATTAGTCTCAGAACAGG	PTGER2	ENSG00000125384	-0.5730738269881066	[283]	[149,58,NaN]	-4	hSpCas9	negative selection	9551730
52314572	52314595	14	-	27869803	HPAFII	viability after 15 days	GCGTCTCGCAGTCCTCAGACTGG	PTGER2	ENSG00000125384	0.5090450516848259	[283]	[598,331,NaN]	6	hSpCas9	negative selection	9634174
52314742	52314765	14	-	27869803	HPAFII	viability after 15 days	GGTCACCAGCACGTGGAACAAGG	PTGER2	ENSG00000125384	-0.5483084136408125	[329]	[326,189,NaN]	-5	hSpCas9	negative selection	9634175
52315105	52315128	14	+	27869803	HPAFII	viability after 15 days	GGTGCTTCATCCGGCACGGGCGG	PTGER2	ENSG00000125384	-0.17635425891487255	[68]	[138,19,NaN]	-2	hSpCas9	negative selection	9634176
52315216	52315239	14	+	27869803	HPAFII	viability after 15 days	TCCGCATGCACCGCCGAAGCCGG	PTGER2	ENSG00000125384	0.4495913670828311	[743]	[1530,818,NaN]	5	hSpCas9	negative selection	9634177
52327235	52327258	14	+	27869803	HPAFII	viability after 15 days	GAATGAAACCTCTTCCCGAAAGG	PTGER2	ENSG00000125384	0.7465073603901464	[177]	[344,305,NaN]	8	hSpCas9	negative selection	9634178
52327338	52327361	14	-	27869803	HPAFII	viability after 15 days	GAACGCATTAGTCTCAGAACAGG	PTGER2	ENSG00000125384	-0.19373208993288132	[283]	[293,249,NaN]	-2	hSpCas9	negative selection	9634179
52314572	52314595	14	-	27869803	ASPC1	viability after 36 days	GCGTCTCGCAGTCCTCAGACTGG	PTGER2	ENSG00000125384	0.644747336259638	[699]	[331,715,147]	6	hSpCas9	negative selection	9716623
52314742	52314765	14	-	27869803	ASPC1	viability after 36 days	GGTCACCAGCACGTGGAACAAGG	PTGER2	ENSG00000125384	0.8340413479296597	[701]	[420,299,551]	7	hSpCas9	negative selection	9716624
52315105	52315128	14	+	27869803	ASPC1	viability after 36 days	GGTGCTTCATCCGGCACGGGCGG	PTGER2	ENSG00000125384	-0.38921096874280336	[173]	[60,89,0]	-4	hSpCas9	negative selection	9716625
52315216	52315239	14	+	27869803	ASPC1	viability after 36 days	TCCGCATGCACCGCCGAAGCCGG	PTGER2	ENSG00000125384	0.6423130191840052	[1817]	[779,1701,562]	6	hSpCas9	negative selection	9716626
52327235	52327258	14	+	27869803	ASPC1	viability after 36 days	GAATGAAACCTCTTCCCGAAAGG	PTGER2	ENSG00000125384	0.9806082536136818	[373]	[239,359,185]	8	hSpCas9	negative selection	9716627
52327338	52327361	14	-	27869803	ASPC1	viability after 36 days	GAACGCATTAGTCTCAGAACAGG	PTGER2	ENSG00000125384	-0.4738311426410974	[861]	[290,221,157]	-5	hSpCas9	negative selection	9716628
52314572	52314595	14	-	27869803	PATU8988S	viability after 35 days	GCGTCTCGCAGTCCTCAGACTGG	PTGER2	ENSG00000125384	-0.019279678303559117	[603]	[253,225,NaN]	0	hSpCas9	negative selection	9799072
52314742	52314765	14	-	27869803	PATU8988S	viability after 35 days	GGTCACCAGCACGTGGAACAAGG	PTGER2	ENSG00000125384	0.6094519080662104	[751]	[496,426,NaN]	6	hSpCas9	negative selection	9799073
52315105	52315128	14	+	27869803	PATU8988S	viability after 35 days	GGTGCTTCATCCGGCACGGGCGG	PTGER2	ENSG00000125384	0.4560393618808787	[114]	[78,47,NaN]	5	hSpCas9	negative selection	9799074
52315216	52315239	14	+	27869803	PATU8988S	viability after 35 days	TCCGCATGCACCGCCGAAGCCGG	PTGER2	ENSG00000125384	-0.5649064533935441	[1571]	[423,431,NaN]	-5	hSpCas9	negative selection	9799075
52327235	52327258	14	+	27869803	PATU8988S	viability after 35 days	GAATGAAACCTCTTCCCGAAAGG	PTGER2	ENSG00000125384	0.8281501361032426	[315]	[205,245,NaN]	8	hSpCas9	negative selection	9799076
52327338	52327361	14	-	27869803	PATU8988S	viability after 35 days	GAACGCATTAGTCTCAGAACAGG	PTGER2	ENSG00000125384	0.49271736027093843	[560]	[283,351,NaN]	5	hSpCas9	negative selection	9799077
52314572	52314595	14	-	27869803	PATU8988S	viability after 31 days	GCGTCTCGCAGTCCTCAGACTGG	PTGER2	ENSG00000125384	-0.13243779263202649	[603]	[202,240,NaN]	-1	hSpCas9	negative selection	9881521
52314742	52314765	14	-	27869803	PATU8988S	viability after 31 days	GGTCACCAGCACGTGGAACAAGG	PTGER2	ENSG00000125384	0.38979761054531104	[751]	[358,435,NaN]	5	hSpCas9	negative selection	9881522
52315105	52315128	14	+	27869803	PATU8988S	viability after 31 days	GGTGCTTCATCCGGCACGGGCGG	PTGER2	ENSG00000125384	0.8187254441216243	[114]	[90,67,NaN]	8	hSpCas9	negative selection	9881523
52315216	52315239	14	+	27869803	PATU8988S	viability after 31 days	TCCGCATGCACCGCCGAAGCCGG	PTGER2	ENSG00000125384	-0.34984937215534906	[1571]	[530,441,NaN]	-4	hSpCas9	negative selection	9881524
52327235	52327258	14	+	27869803	PATU8988S	viability after 31 days	GAATGAAACCTCTTCCCGAAAGG	PTGER2	ENSG00000125384	0.5151210077109615	[315]	[143,225,NaN]	6	hSpCas9	negative selection	9881525
52327338	52327361	14	-	27869803	PATU8988S	viability after 31 days	GAACGCATTAGTCTCAGAACAGG	PTGER2	ENSG00000125384	0.24291483305329192	[560]	[247,285,NaN]	3	hSpCas9	negative selection	9881526
52314572	52314595	14	-	27869803	HPAFII	viability after 35 days	GCGTCTCGCAGTCCTCAGACTGG	PTGER2	ENSG00000125384	0.21341409910313106	[283]	[145,189,NaN]	1	hSpCas9	negative selection	9963970
52314742	52314765	14	-	27869803	HPAFII	viability after 35 days	GGTCACCAGCACGTGGAACAAGG	PTGER2	ENSG00000125384	-1.0004952233591633	[329]	[27,145,NaN]	-5	hSpCas9	negative selection	9963971
52315105	52315128	14	+	27869803	HPAFII	viability after 35 days	GGTGCTTCATCCGGCACGGGCGG	PTGER2	ENSG00000125384	-0.8298188974233192	[68]	[29,7,NaN]	-5	hSpCas9	negative selection	9963972
52315216	52315239	14	+	27869803	HPAFII	viability after 35 days	TCCGCATGCACCGCCGAAGCCGG	PTGER2	ENSG00000125384	0.40179762827468	[743]	[419,584,NaN]	2	hSpCas9	negative selection	9963973
52327235	52327258	14	+	27869803	HPAFII	viability after 35 days	GAATGAAACCTCTTCCCGAAAGG	PTGER2	ENSG00000125384	0.5325778339211242	[177]	[119,141,NaN]	3	hSpCas9	negative selection	9963974
52327338	52327361	14	-	27869803	HPAFII	viability after 35 days	GAACGCATTAGTCTCAGAACAGG	PTGER2	ENSG00000125384	-0.35040944796991025	[283]	[124,98,NaN]	-2	hSpCas9	negative selection	9963975
52314572	52314595	14	-	27869803	HPAFII	viability after 31 days	GCGTCTCGCAGTCCTCAGACTGG	PTGER2	ENSG00000125384	0.39580713137980583	[283]	[202,216,NaN]	3	hSpCas9	negative selection	10046419
52314742	52314765	14	-	27869803	HPAFII	viability after 31 days	GGTCACCAGCACGTGGAACAAGG	PTGER2	ENSG00000125384	-1.5802513621898475	[329]	[26,99,NaN]	-7	hSpCas9	negative selection	10046420
52315105	52315128	14	+	27869803	HPAFII	viability after 31 days	GGTGCTTCATCCGGCACGGGCGG	PTGER2	ENSG00000125384	-0.624306654422571	[68]	[38,9,NaN]	-4	hSpCas9	negative selection	10046421
52315216	52315239	14	+	27869803	HPAFII	viability after 31 days	TCCGCATGCACCGCCGAAGCCGG	PTGER2	ENSG00000125384	0.29760982845166817	[743]	[528,495,NaN]	2	hSpCas9	negative selection	10046422
52327235	52327258	14	+	27869803	HPAFII	viability after 31 days	GAATGAAACCTCTTCCCGAAAGG	PTGER2	ENSG00000125384	0.7765746091180977	[177]	[173,167,NaN]	5	hSpCas9	negative selection	10046423
52327338	52327361	14	-	27869803	HPAFII	viability after 31 days	GAACGCATTAGTCTCAGAACAGG	PTGER2	ENSG00000125384	-0.5071819981080393	[283]	[159,59,NaN]	-3	hSpCas9	negative selection	10046424
52315301	52315324	14	+	28162770	P31FUJ	viability	GGAAAGGGTGTCCATGGCGGAGG	PTGER2	ENSG00000125384	0.41253291428625927	[38]	[60]	4	hSpCas9	negative selection	10219451
52314824	52314847	14	+	28162770	P31FUJ	viability	GTACGCGCGGAACCAGACCCTGG	PTGER2	ENSG00000125384	-0.3786530708778334	[467]	[422]	-3	hSpCas9	negative selection	10219452
52314737	52314760	14	-	28162770	P31FUJ	viability	CCAGCACGTGGAACAAGGAGAGG	PTGER2	ENSG00000125384	0.8406037373118822	[181]	[382]	8	hSpCas9	negative selection	10219453
52315105	52315128	14	+	28162770	P31FUJ	viability	GGTGCTTCATCCGGCACGGGCGG	PTGER2	ENSG00000125384	0.41105398536034604	[127]	[199]	4	hSpCas9	negative selection	10219454
52315150	52315173	14	-	28162770	P31FUJ	viability	AATGAGAAGCAGCAGCAGGGTGG	PTGER2	ENSG00000125384	0.04778509509208417	[176]	[214]	0	hSpCas9	negative selection	10219455
52315331	52315354	14	-	28162770	P31FUJ	viability	TGATAGCCAGGAGAATGAGGTGG	PTGER2	ENSG00000125384	0.1727438458871674	[304]	[403]	1	hSpCas9	negative selection	10219456
52314580	52314603	14	+	28162770	P31FUJ	viability	AGGACTGCGAGACGCGACAGTGG	PTGER2	ENSG00000125384	0.29172444244480356	[129]	[186]	3	hSpCas9	negative selection	10219457
52314656	52314679	14	+	28162770	P31FUJ	viability	GCTGGGGAACCTCATAGCACTGG	PTGER2	ENSG00000125384	-0.08146410062889636	[216]	[240]	-1	hSpCas9	negative selection	10219458
52314749	52314772	14	-	28162770	P31FUJ	viability	CCAGCTCGGTCACCAGCACGTGG	PTGER2	ENSG00000125384	0.27815971486300073	[159]	[227]	3	hSpCas9	negative selection	10219459
52314791	52314814	14	+	28162770	P31FUJ	viability	GACCTGCCTCATCAGCCCAGTGG	PTGER2	ENSG00000125384	-0.11516272017576079	[717]	[778]	-1	hSpCas9	negative selection	10219460
52315301	52315324	14	+	28162770	TF1	viability	GGAAAGGGTGTCCATGGCGGAGG	PTGER2	ENSG00000125384	NaN	[NaN]	[54]	1	hSpCas9	negative selection	10388817
52314824	52314847	14	+	28162770	TF1	viability	GTACGCGCGGAACCAGACCCTGG	PTGER2	ENSG00000125384	NaN	[NaN]	[181]	1	hSpCas9	negative selection	10388818
52314737	52314760	14	-	28162770	TF1	viability	CCAGCACGTGGAACAAGGAGAGG	PTGER2	ENSG00000125384	NaN	[NaN]	[276]	1	hSpCas9	negative selection	10388819
52315105	52315128	14	+	28162770	TF1	viability	GGTGCTTCATCCGGCACGGGCGG	PTGER2	ENSG00000125384	NaN	[NaN]	[244]	1	hSpCas9	negative selection	10388820
52315150	52315173	14	-	28162770	TF1	viability	AATGAGAAGCAGCAGCAGGGTGG	PTGER2	ENSG00000125384	NaN	[NaN]	[276]	1	hSpCas9	negative selection	10388821
52315331	52315354	14	-	28162770	TF1	viability	TGATAGCCAGGAGAATGAGGTGG	PTGER2	ENSG00000125384	NaN	[NaN]	[280]	1	hSpCas9	negative selection	10388822
52314580	52314603	14	+	28162770	TF1	viability	AGGACTGCGAGACGCGACAGTGG	PTGER2	ENSG00000125384	NaN	[NaN]	[107]	1	hSpCas9	negative selection	10388823
52314656	52314679	14	+	28162770	TF1	viability	GCTGGGGAACCTCATAGCACTGG	PTGER2	ENSG00000125384	NaN	[NaN]	[185]	1	hSpCas9	negative selection	10388824
52314749	52314772	14	-	28162770	TF1	viability	CCAGCTCGGTCACCAGCACGTGG	PTGER2	ENSG00000125384	NaN	[NaN]	[192]	1	hSpCas9	negative selection	10388825
52314791	52314814	14	+	28162770	TF1	viability	GACCTGCCTCATCAGCCCAGTGG	PTGER2	ENSG00000125384	NaN	[NaN]	[589]	1	hSpCas9	negative selection	10388826
52315301	52315324	14	+	28162770	SKM1	viability	GGAAAGGGTGTCCATGGCGGAGG	PTGER2	ENSG00000125384	0.7994866787242647	[12]	[39]	7	hSpCas9	negative selection	10558183
52314824	52314847	14	+	28162770	SKM1	viability	GTACGCGCGGAACCAGACCCTGG	PTGER2	ENSG00000125384	0.1032305335760223	[98]	[187]	1	hSpCas9	negative selection	10558184
52314737	52314760	14	-	28162770	SKM1	viability	CCAGCACGTGGAACAAGGAGAGG	PTGER2	ENSG00000125384	0.5848152944518699	[65]	[174]	5	hSpCas9	negative selection	10558185
52315105	52315128	14	+	28162770	SKM1	viability	GGTGCTTCATCCGGCACGGGCGG	PTGER2	ENSG00000125384	1.4570709179035597	[40]	[198]	9	hSpCas9	negative selection	10558186
52315150	52315173	14	-	28162770	SKM1	viability	AATGAGAAGCAGCAGCAGGGTGG	PTGER2	ENSG00000125384	0.5975371934917791	[39]	[106]	6	hSpCas9	negative selection	10558187
52315331	52315354	14	-	28162770	SKM1	viability	TGATAGCCAGGAGAATGAGGTGG	PTGER2	ENSG00000125384	0.13440903343031174	[83]	[162]	1	hSpCas9	negative selection	10558188
52314580	52314603	14	+	28162770	SKM1	viability	AGGACTGCGAGACGCGACAGTGG	PTGER2	ENSG00000125384	0.2186402864753405	[34]	[71]	2	hSpCas9	negative selection	10558189
52314656	52314679	14	+	28162770	SKM1	viability	GCTGGGGAACCTCATAGCACTGG	PTGER2	ENSG00000125384	0.9280200489696471	[54]	[184]	8	hSpCas9	negative selection	10558190
52314749	52314772	14	-	28162770	SKM1	viability	CCAGCTCGGTCACCAGCACGTGG	PTGER2	ENSG00000125384	0.32686168789247727	[22]	[50]	3	hSpCas9	negative selection	10558191
52314791	52314814	14	+	28162770	SKM1	viability	GACCTGCCTCATCAGCCCAGTGG	PTGER2	ENSG00000125384	0.7217381399726379	[141]	[413]	7	hSpCas9	negative selection	10558192
52315301	52315324	14	+	28162770	SKM1	viability	GGAAAGGGTGTCCATGGCGGAGG	PTGER2	ENSG00000125384	0.7994866787242647	[12]	[39]	7	hSpCas9	negative selection	10727549
52314824	52314847	14	+	28162770	SKM1	viability	GTACGCGCGGAACCAGACCCTGG	PTGER2	ENSG00000125384	0.1032305335760223	[98]	[187]	1	hSpCas9	negative selection	10727550
52314737	52314760	14	-	28162770	SKM1	viability	CCAGCACGTGGAACAAGGAGAGG	PTGER2	ENSG00000125384	0.5848152944518699	[65]	[174]	5	hSpCas9	negative selection	10727551
52315105	52315128	14	+	28162770	SKM1	viability	GGTGCTTCATCCGGCACGGGCGG	PTGER2	ENSG00000125384	1.4570709179035597	[40]	[198]	9	hSpCas9	negative selection	10727552
52315150	52315173	14	-	28162770	SKM1	viability	AATGAGAAGCAGCAGCAGGGTGG	PTGER2	ENSG00000125384	0.5975371934917791	[39]	[106]	6	hSpCas9	negative selection	10727553
52315331	52315354	14	-	28162770	SKM1	viability	TGATAGCCAGGAGAATGAGGTGG	PTGER2	ENSG00000125384	0.13440903343031174	[83]	[162]	1	hSpCas9	negative selection	10727554
52314580	52314603	14	+	28162770	SKM1	viability	AGGACTGCGAGACGCGACAGTGG	PTGER2	ENSG00000125384	0.2186402864753405	[34]	[71]	2	hSpCas9	negative selection	10727555
52314656	52314679	14	+	28162770	SKM1	viability	GCTGGGGAACCTCATAGCACTGG	PTGER2	ENSG00000125384	0.9280200489696471	[54]	[184]	8	hSpCas9	negative selection	10727556
52314749	52314772	14	-	28162770	SKM1	viability	CCAGCTCGGTCACCAGCACGTGG	PTGER2	ENSG00000125384	0.32686168789247727	[22]	[50]	3	hSpCas9	negative selection	10727557
52314791	52314814	14	+	28162770	SKM1	viability	GACCTGCCTCATCAGCCCAGTGG	PTGER2	ENSG00000125384	0.7217381399726379	[141]	[413]	7	hSpCas9	negative selection	10727558
52315301	52315324	14	+	28162770	PL21	viability	GGAAAGGGTGTCCATGGCGGAGG	PTGER2	ENSG00000125384	1.320433848207032	[22]	[24]	9	hSpCas9	negative selection	10896915
52314824	52314847	14	+	28162770	PL21	viability	GTACGCGCGGAACCAGACCCTGG	PTGER2	ENSG00000125384	0.4597225951341848	[278]	[166]	4	hSpCas9	negative selection	10896916
52314737	52314760	14	-	28162770	PL21	viability	CCAGCACGTGGAACAAGGAGAGG	PTGER2	ENSG00000125384	0.853689200467889	[177]	[139]	7	hSpCas9	negative selection	10896917
52315105	52315128	14	+	28162770	PL21	viability	GGTGCTTCATCCGGCACGGGCGG	PTGER2	ENSG00000125384	-0.43729030612597164	[139]	[44]	-3	hSpCas9	negative selection	10896918
52315150	52315173	14	-	28162770	PL21	viability	AATGAGAAGCAGCAGCAGGGTGG	PTGER2	ENSG00000125384	-0.27851398408549544	[169]	[60]	-2	hSpCas9	negative selection	10896919
52315331	52315354	14	-	28162770	PL21	viability	TGATAGCCAGGAGAATGAGGTGG	PTGER2	ENSG00000125384	-0.6208902444653606	[317]	[89]	-4	hSpCas9	negative selection	10896920
52314580	52314603	14	+	28162770	PL21	viability	AGGACTGCGAGACGCGACAGTGG	PTGER2	ENSG00000125384	0.6714453334149091	[87]	[60]	6	hSpCas9	negative selection	10896921
52314656	52314679	14	+	28162770	PL21	viability	GCTGGGGAACCTCATAGCACTGG	PTGER2	ENSG00000125384	0.34846236144642156	[156]	[86]	3	hSpCas9	negative selection	10896922
52314749	52314772	14	-	28162770	PL21	viability	CCAGCTCGGTCACCAGCACGTGG	PTGER2	ENSG00000125384	-2.0818957532745292	[106]	[10]	-8	hSpCas9	negative selection	10896923
52314791	52314814	14	+	28162770	PL21	viability	GACCTGCCTCATCAGCCCAGTGG	PTGER2	ENSG00000125384	0.3552804644256293	[642]	[357]	3	hSpCas9	negative selection	10896924
52315301	52315324	14	+	28162770	P31FUJ	viability	GGAAAGGGTGTCCATGGCGGAGG	PTGER2	ENSG00000125384	0.41253291428625927	[38]	[60]	4	hSpCas9	negative selection	11066281
52314824	52314847	14	+	28162770	P31FUJ	viability	GTACGCGCGGAACCAGACCCTGG	PTGER2	ENSG00000125384	-0.3786530708778334	[467]	[422]	-3	hSpCas9	negative selection	11066282
52314737	52314760	14	-	28162770	P31FUJ	viability	CCAGCACGTGGAACAAGGAGAGG	PTGER2	ENSG00000125384	0.8406037373118822	[181]	[382]	8	hSpCas9	negative selection	11066283
52315105	52315128	14	+	28162770	P31FUJ	viability	GGTGCTTCATCCGGCACGGGCGG	PTGER2	ENSG00000125384	0.41105398536034604	[127]	[199]	4	hSpCas9	negative selection	11066284
52315150	52315173	14	-	28162770	P31FUJ	viability	AATGAGAAGCAGCAGCAGGGTGG	PTGER2	ENSG00000125384	0.04778509509208417	[176]	[214]	0	hSpCas9	negative selection	11066285
52315331	52315354	14	-	28162770	P31FUJ	viability	TGATAGCCAGGAGAATGAGGTGG	PTGER2	ENSG00000125384	0.1727438458871674	[304]	[403]	1	hSpCas9	negative selection	11066286
52314580	52314603	14	+	28162770	P31FUJ	viability	AGGACTGCGAGACGCGACAGTGG	PTGER2	ENSG00000125384	0.29172444244480356	[129]	[186]	3	hSpCas9	negative selection	11066287
52314656	52314679	14	+	28162770	P31FUJ	viability	GCTGGGGAACCTCATAGCACTGG	PTGER2	ENSG00000125384	-0.08146410062889636	[216]	[240]	-1	hSpCas9	negative selection	11066288
52314749	52314772	14	-	28162770	P31FUJ	viability	CCAGCTCGGTCACCAGCACGTGG	PTGER2	ENSG00000125384	0.27815971486300073	[159]	[227]	3	hSpCas9	negative selection	11066289
52314791	52314814	14	+	28162770	P31FUJ	viability	GACCTGCCTCATCAGCCCAGTGG	PTGER2	ENSG00000125384	-0.11516272017576079	[717]	[778]	-1	hSpCas9	negative selection	11066290
52315301	52315324	14	+	28162770	OCIAML5	viability	GGAAAGGGTGTCCATGGCGGAGG	PTGER2	ENSG00000125384	0.25227008895073855	[19]	[42]	2	hSpCas9	negative selection	11235647
52314824	52314847	14	+	28162770	OCIAML5	viability	GTACGCGCGGAACCAGACCCTGG	PTGER2	ENSG00000125384	0.033555407990870256	[163]	[302]	0	hSpCas9	negative selection	11235648
52314737	52314760	14	-	28162770	OCIAML5	viability	CCAGCACGTGGAACAAGGAGAGG	PTGER2	ENSG00000125384	0.9187624751684933	[79]	[272]	7	hSpCas9	negative selection	11235649
52315105	52315128	14	+	28162770	OCIAML5	viability	GGTGCTTCATCCGGCACGGGCGG	PTGER2	ENSG00000125384	1.062203555110119	[90]	[342]	8	hSpCas9	negative selection	11235650
52315150	52315173	14	-	28162770	OCIAML5	viability	AATGAGAAGCAGCAGCAGGGTGG	PTGER2	ENSG00000125384	-0.2737068049670881	[72]	[108]	-2	hSpCas9	negative selection	11235651
52315331	52315354	14	-	28162770	OCIAML5	viability	TGATAGCCAGGAGAATGAGGTGG	PTGER2	ENSG00000125384	-0.13934852294446817	[143]	[235]	-1	hSpCas9	negative selection	11235652
52314580	52314603	14	+	28162770	OCIAML5	viability	AGGACTGCGAGACGCGACAGTGG	PTGER2	ENSG00000125384	-0.028446594443608766	[125]	[222]	0	hSpCas9	negative selection	11235653
52314656	52314679	14	+	28162770	OCIAML5	viability	GCTGGGGAACCTCATAGCACTGG	PTGER2	ENSG00000125384	-0.228920876254953	[86]	[133]	-2	hSpCas9	negative selection	11235654
52314749	52314772	14	-	28162770	OCIAML5	viability	CCAGCTCGGTCACCAGCACGTGG	PTGER2	ENSG00000125384	0.9372544283633455	[45]	[158]	7	hSpCas9	negative selection	11235655
52314791	52314814	14	+	28162770	OCIAML5	viability	GACCTGCCTCATCAGCCCAGTGG	PTGER2	ENSG00000125384	0.1607574694935867	[391]	[790]	1	hSpCas9	negative selection	11235656
52315301	52315324	14	+	28162770	EOL1	viability	GGAAAGGGTGTCCATGGCGGAGG	PTGER2	ENSG00000125384	1.740123200433107	[49]	[87]	9	hSpCas9	negative selection	11405013
52314824	52314847	14	+	28162770	EOL1	viability	GTACGCGCGGAACCAGACCCTGG	PTGER2	ENSG00000125384	-1.2081661507747055	[420]	[95]	-7	hSpCas9	negative selection	11405014
52314737	52314760	14	-	28162770	EOL1	viability	CCAGCACGTGGAACAAGGAGAGG	PTGER2	ENSG00000125384	0.5758832942110447	[353]	[277]	5	hSpCas9	negative selection	11405015
52315105	52315128	14	+	28162770	EOL1	viability	GGTGCTTCATCCGGCACGGGCGG	PTGER2	ENSG00000125384	0.13258489992991238	[302]	[174]	1	hSpCas9	negative selection	11405016
52315150	52315173	14	-	28162770	EOL1	viability	AATGAGAAGCAGCAGCAGGGTGG	PTGER2	ENSG00000125384	0.2676216753294456	[297]	[188]	2	hSpCas9	negative selection	11405017
52315331	52315354	14	-	28162770	EOL1	viability	TGATAGCCAGGAGAATGAGGTGG	PTGER2	ENSG00000125384	0.33822359539115343	[529]	[352]	3	hSpCas9	negative selection	11405018
52314580	52314603	14	+	28162770	EOL1	viability	AGGACTGCGAGACGCGACAGTGG	PTGER2	ENSG00000125384	0.02838358255507445	[133]	[71]	0	hSpCas9	negative selection	11405019
52314656	52314679	14	+	28162770	EOL1	viability	GCTGGGGAACCTCATAGCACTGG	PTGER2	ENSG00000125384	-0.48687847415593044	[265]	[99]	-4	hSpCas9	negative selection	11405020
52314749	52314772	14	-	28162770	EOL1	viability	CCAGCTCGGTCACCAGCACGTGG	PTGER2	ENSG00000125384	0.7080559516737707	[121]	[104]	6	hSpCas9	negative selection	11405021
52314791	52314814	14	+	28162770	EOL1	viability	GACCTGCCTCATCAGCCCAGTGG	PTGER2	ENSG00000125384	0.27883123977028235	[775]	[495]	2	hSpCas9	negative selection	11405022
52315301	52315324	14	+	28162770	MOLM13	viability	GGAAAGGGTGTCCATGGCGGAGG	PTGER2	ENSG00000125384	-1.1170731191765775	[53]	[17]	-5	hSpCas9	negative selection	11574379
52314824	52314847	14	+	28162770	MOLM13	viability	GTACGCGCGGAACCAGACCCTGG	PTGER2	ENSG00000125384	-0.15865222292797654	[439]	[284]	-1	hSpCas9	negative selection	11574380
52314737	52314760	14	-	28162770	MOLM13	viability	CCAGCACGTGGAACAAGGAGAGG	PTGER2	ENSG00000125384	0.4183073526940184	[295]	[285]	3	hSpCas9	negative selection	11574381
52315105	52315128	14	+	28162770	MOLM13	viability	GGTGCTTCATCCGGCACGGGCGG	PTGER2	ENSG00000125384	0.3518655852050955	[219]	[202]	2	hSpCas9	negative selection	11574382
52315150	52315173	14	-	28162770	MOLM13	viability	AATGAGAAGCAGCAGCAGGGTGG	PTGER2	ENSG00000125384	0.24345781493453234	[235]	[201]	1	hSpCas9	negative selection	11574383
52315331	52315354	14	-	28162770	MOLM13	viability	TGATAGCCAGGAGAATGAGGTGG	PTGER2	ENSG00000125384	0.5555420635795711	[446]	[474]	4	hSpCas9	negative selection	11574384
52314580	52314603	14	+	28162770	MOLM13	viability	AGGACTGCGAGACGCGACAGTGG	PTGER2	ENSG00000125384	0.7898174764319412	[143]	[179]	6	hSpCas9	negative selection	11574385
52314656	52314679	14	+	28162770	MOLM13	viability	GCTGGGGAACCTCATAGCACTGG	PTGER2	ENSG00000125384	-1.3608391913055924	[237]	[66]	-6	hSpCas9	negative selection	11574386
52314749	52314772	14	-	28162770	MOLM13	viability	CCAGCTCGGTCACCAGCACGTGG	PTGER2	ENSG00000125384	0.12211454470284866	[121]	[95]	0	hSpCas9	negative selection	11574387
52314791	52314814	14	+	28162770	MOLM13	viability	GACCTGCCTCATCAGCCCAGTGG	PTGER2	ENSG00000125384	-0.1425936398576162	[883]	[578]	-1	hSpCas9	negative selection	11574388
52315301	52315324	14	+	28162770	HEL	viability	GGAAAGGGTGTCCATGGCGGAGG	PTGER2	ENSG00000125384	-1.0353330731122812	[47]	[14]	-6	hSpCas9	negative selection	11743745
52314824	52314847	14	+	28162770	HEL	viability	GTACGCGCGGAACCAGACCCTGG	PTGER2	ENSG00000125384	0.0287034070828871	[400]	[261]	0	hSpCas9	negative selection	11743746
52314737	52314760	14	-	28162770	HEL	viability	CCAGCACGTGGAACAAGGAGAGG	PTGER2	ENSG00000125384	0.905773237834151	[264]	[317]	7	hSpCas9	negative selection	11743747
52315105	52315128	14	+	28162770	HEL	viability	GGTGCTTCATCCGGCACGGGCGG	PTGER2	ENSG00000125384	0.09810842531441885	[193]	[132]	0	hSpCas9	negative selection	11743748
52315150	52315173	14	-	28162770	HEL	viability	AATGAGAAGCAGCAGCAGGGTGG	PTGER2	ENSG00000125384	1.2652981193791646	[201]	[310]	9	hSpCas9	negative selection	11743749
52315331	52315354	14	-	28162770	HEL	viability	TGATAGCCAGGAGAATGAGGTGG	PTGER2	ENSG00000125384	-0.1655483647526217	[386]	[220]	-1	hSpCas9	negative selection	11743750
52314580	52314603	14	+	28162770	HEL	viability	AGGACTGCGAGACGCGACAGTGG	PTGER2	ENSG00000125384	0.7434328316198299	[82]	[88]	6	hSpCas9	negative selection	11743751
52314656	52314679	14	+	28162770	HEL	viability	GCTGGGGAACCTCATAGCACTGG	PTGER2	ENSG00000125384	-0.2359548717775094	[227]	[123]	-2	hSpCas9	negative selection	11743752
52314749	52314772	14	-	28162770	HEL	viability	CCAGCTCGGTCACCAGCACGTGG	PTGER2	ENSG00000125384	-0.06775455080465831	[125]	[76]	0	hSpCas9	negative selection	11743753
52314791	52314814	14	+	28162770	HEL	viability	GACCTGCCTCATCAGCCCAGTGG	PTGER2	ENSG00000125384	-0.42622279162718346	[706]	[336]	-3	hSpCas9	negative selection	11743754
52315301	52315324	14	+	28162770	MV411	viability	GGAAAGGGTGTCCATGGCGGAGG	PTGER2	ENSG00000125384	0.014776793992500092	[46]	[39]	0	hSpCas9	negative selection	11913111
52314824	52314847	14	+	28162770	MV411	viability	GTACGCGCGGAACCAGACCCTGG	PTGER2	ENSG00000125384	-0.0012415620739484323	[359]	[302]	0	hSpCas9	negative selection	11913112
52314737	52314760	14	-	28162770	MV411	viability	CCAGCACGTGGAACAAGGAGAGG	PTGER2	ENSG00000125384	-0.3308302973643725	[214]	[143]	-2	hSpCas9	negative selection	11913113
52315105	52315128	14	+	28162770	MV411	viability	GGTGCTTCATCCGGCACGGGCGG	PTGER2	ENSG00000125384	-0.3334088414661489	[174]	[116]	-3	hSpCas9	negative selection	11913114
52315150	52315173	14	-	28162770	MV411	viability	AATGAGAAGCAGCAGCAGGGTGG	PTGER2	ENSG00000125384	0.18371195317238811	[161]	[154]	1	hSpCas9	negative selection	11913115
52315331	52315354	14	-	28162770	MV411	viability	TGATAGCCAGGAGAATGAGGTGG	PTGER2	ENSG00000125384	-0.15963363868601177	[300]	[226]	-1	hSpCas9	negative selection	11913116
52314580	52314603	14	+	28162770	MV411	viability	AGGACTGCGAGACGCGACAGTGG	PTGER2	ENSG00000125384	-0.8253187916525387	[121]	[57]	-5	hSpCas9	negative selection	11913117
52314656	52314679	14	+	28162770	MV411	viability	GCTGGGGAACCTCATAGCACTGG	PTGER2	ENSG00000125384	0.5975363183612986	[141]	[180]	5	hSpCas9	negative selection	11913118
52314749	52314772	14	-	28162770	MV411	viability	CCAGCTCGGTCACCAGCACGTGG	PTGER2	ENSG00000125384	0.1625486531962621	[69]	[65]	1	hSpCas9	negative selection	11913119
52314791	52314814	14	+	28162770	MV411	viability	GACCTGCCTCATCAGCCCAGTGG	PTGER2	ENSG00000125384	-0.03308428177985956	[497]	[409]	0	hSpCas9	negative selection	11913120
52315301	52315324	14	+	28162770	MONOMAC1	viability	GGAAAGGGTGTCCATGGCGGAGG	PTGER2	ENSG00000125384	2.1006437015811317	[11]	[58]	9	hSpCas9	negative selection	12082477
52314824	52314847	14	+	28162770	MONOMAC1	viability	GTACGCGCGGAACCAGACCCTGG	PTGER2	ENSG00000125384	0.46298860263563046	[180]	[285]	4	hSpCas9	negative selection	12082478
52314737	52314760	14	-	28162770	MONOMAC1	viability	CCAGCACGTGGAACAAGGAGAGG	PTGER2	ENSG00000125384	0.07373320755384533	[154]	[186]	0	hSpCas9	negative selection	12082479
52315105	52315128	14	+	28162770	MONOMAC1	viability	GGTGCTTCATCCGGCACGGGCGG	PTGER2	ENSG00000125384	-0.043790586763871736	[115]	[128]	0	hSpCas9	negative selection	12082480
52315150	52315173	14	-	28162770	MONOMAC1	viability	AATGAGAAGCAGCAGCAGGGTGG	PTGER2	ENSG00000125384	0.18230894507598147	[132]	[172]	1	hSpCas9	negative selection	12082481
52315331	52315354	14	-	28162770	MONOMAC1	viability	TGATAGCCAGGAGAATGAGGTGG	PTGER2	ENSG00000125384	0.8594164212696266	[212]	[442]	7	hSpCas9	negative selection	12082482
52314580	52314603	14	+	28162770	MONOMAC1	viability	AGGACTGCGAGACGCGACAGTGG	PTGER2	ENSG00000125384	-0.7609377322528802	[67]	[45]	-6	hSpCas9	negative selection	12082483
52314656	52314679	14	+	28162770	MONOMAC1	viability	GCTGGGGAACCTCATAGCACTGG	PTGER2	ENSG00000125384	0.23548807894813112	[122]	[165]	2	hSpCas9	negative selection	12082484
52314749	52314772	14	-	28162770	MONOMAC1	viability	CCAGCTCGGTCACCAGCACGTGG	PTGER2	ENSG00000125384	0.7605278866200497	[68]	[133]	7	hSpCas9	negative selection	12082485
52314791	52314814	14	+	28162770	MONOMAC1	viability	GACCTGCCTCATCAGCCCAGTGG	PTGER2	ENSG00000125384	-0.2803271904205895	[409]	[386]	-2	hSpCas9	negative selection	12082486
52315301	52315324	14	+	28162770	OCIAML2	viability	GGAAAGGGTGTCCATGGCGGAGG	PTGER2	ENSG00000125384	-1.0231708482709398	[10]	[29]	-6	hSpCas9	negative selection	12251843
52314824	52314847	14	+	28162770	OCIAML2	viability	GTACGCGCGGAACCAGACCCTGG	PTGER2	ENSG00000125384	0.31435728378698824	[64]	[447]	3	hSpCas9	negative selection	12251844
52314737	52314760	14	-	28162770	OCIAML2	viability	CCAGCACGTGGAACAAGGAGAGG	PTGER2	ENSG00000125384	0.8986039844235579	[29]	[309]	8	hSpCas9	negative selection	12251845
52315105	52315128	14	+	28162770	OCIAML2	viability	GGTGCTTCATCCGGCACGGGCGG	PTGER2	ENSG00000125384	0.7968504856228246	[26]	[259]	7	hSpCas9	negative selection	12251846
52315150	52315173	14	-	28162770	OCIAML2	viability	AATGAGAAGCAGCAGCAGGGTGG	PTGER2	ENSG00000125384	-0.0046553607380920015	[39]	[220]	0	hSpCas9	negative selection	12251847
52315331	52315354	14	-	28162770	OCIAML2	viability	TGATAGCCAGGAGAATGAGGTGG	PTGER2	ENSG00000125384	-0.09960718082662928	[51]	[268]	-1	hSpCas9	negative selection	12251848
52314580	52314603	14	+	28162770	OCIAML2	viability	AGGACTGCGAGACGCGACAGTGG	PTGER2	ENSG00000125384	-0.8629472480209216	[20]	[63]	-6	hSpCas9	negative selection	12251849
52314656	52314679	14	+	28162770	OCIAML2	viability	GCTGGGGAACCTCATAGCACTGG	PTGER2	ENSG00000125384	0.2735312703282491	[29]	[200]	2	hSpCas9	negative selection	12251850
52314749	52314772	14	-	28162770	OCIAML2	viability	CCAGCTCGGTCACCAGCACGTGG	PTGER2	ENSG00000125384	0.30195967865476636	[17]	[122]	3	hSpCas9	negative selection	12251851
52314791	52314814	14	+	28162770	OCIAML2	viability	GACCTGCCTCATCAGCCCAGTGG	PTGER2	ENSG00000125384	-0.013629032859626244	[107]	[592]	0	hSpCas9	negative selection	12251852
52315301	52315324	14	+	28162770	OCIAML3	viability	GGAAAGGGTGTCCATGGCGGAGG	PTGER2	ENSG00000125384	1.8292037904003808	[10]	[117]	9	hSpCas9	negative selection	12421209
52314824	52314847	14	+	28162770	OCIAML3	viability	GTACGCGCGGAACCAGACCCTGG	PTGER2	ENSG00000125384	-0.062394564195940694	[100]	[291]	0	hSpCas9	negative selection	12421210
52314737	52314760	14	-	28162770	OCIAML3	viability	CCAGCACGTGGAACAAGGAGAGG	PTGER2	ENSG00000125384	0.6168891421744553	[53]	[249]	5	hSpCas9	negative selection	12421211
52315105	52315128	14	+	28162770	OCIAML3	viability	GGTGCTTCATCCGGCACGGGCGG	PTGER2	ENSG00000125384	0.290515142255901	[38]	[143]	2	hSpCas9	negative selection	12421212
52315150	52315173	14	-	28162770	OCIAML3	viability	AATGAGAAGCAGCAGCAGGGTGG	PTGER2	ENSG00000125384	-0.5028597522659678	[45]	[97]	-4	hSpCas9	negative selection	12421213
52315331	52315354	14	-	28162770	OCIAML3	viability	TGATAGCCAGGAGAATGAGGTGG	PTGER2	ENSG00000125384	0.3414521074811262	[79]	[305]	3	hSpCas9	negative selection	12421214
52314580	52314603	14	+	28162770	OCIAML3	viability	AGGACTGCGAGACGCGACAGTGG	PTGER2	ENSG00000125384	1.4566184327458047	[13]	[115]	9	hSpCas9	negative selection	12421215
52314656	52314679	14	+	28162770	OCIAML3	viability	GCTGGGGAACCTCATAGCACTGG	PTGER2	ENSG00000125384	0.11748726632592466	[39]	[130]	1	hSpCas9	negative selection	12421216
52314749	52314772	14	-	28162770	OCIAML3	viability	CCAGCTCGGTCACCAGCACGTGG	PTGER2	ENSG00000125384	0.07584375798350607	[21]	[69]	0	hSpCas9	negative selection	12421217
52314791	52314814	14	+	28162770	OCIAML3	viability	GACCTGCCTCATCAGCCCAGTGG	PTGER2	ENSG00000125384	0.25346186902480805	[151]	[546]	2	hSpCas9	negative selection	12421218