Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:5734
• Symbol:PTGER4
• Description:prostaglandin E receptor 4

DataSource: http://genomecrispr.dkfz.de/#!/results/PTGER4

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
40681068	40681091	5	+	26472758	Jiyoye	viability	GGTGATGTTCATCTTCGGGGTGG	PTGER4	ENSG00000171522	0.3848075684774187	[64]	[63]	3	hSpCas9	negative selection	130658
40681233	40681256	5	+	26472758	Jiyoye	viability	CATGAAGGGCCAATGGCCCGGGG	PTGER4	ENSG00000171522	0.7822148128527981	[63]	[82]	5	hSpCas9	negative selection	130659
40680998	40681021	5	-	26472758	Jiyoye	viability	GGACGAATTGACCCCGGGAGTGG	PTGER4	ENSG00000171522	-0.5627673846379466	[189]	[96]	-4	hSpCas9	negative selection	130660
40681022	40681045	5	-	26472758	Jiyoye	viability	CAGCCGGTCGGGGCTCAAGGAGG	PTGER4	ENSG00000171522	0.6136262589732997	[12]	[14]	4	hSpCas9	negative selection	130661
40681047	40681070	5	+	26472758	Jiyoye	viability	CAGCCCAGTGACCATCCCGGCGG	PTGER4	ENSG00000171522	-0.22218123857373628	[98]	[63]	-1	hSpCas9	negative selection	130662
40681143	40681166	5	+	26472758	Jiyoye	viability	GGAGACGACCTTCTACACGCTGG	PTGER4	ENSG00000171522	2.706735663364781	[12]	[63]	9	hSpCas9	negative selection	130663
40681261	40681284	5	-	26472758	Jiyoye	viability	AAGGTGCTGTACTCGCACAGCGG	PTGER4	ENSG00000171522	-0.1333929998568293	[63]	[43]	-1	hSpCas9	negative selection	130664
40681586	40681609	5	-	26472758	Jiyoye	viability	AAGCACGTTGCAGAGGACGGTGG	PTGER4	ENSG00000171522	-1.5928246184941264	[23]	[5]	-8	hSpCas9	negative selection	130665
40681727	40681750	5	-	26472758	Jiyoye	viability	GCTGAGGCGCGGCAAGGCTGGGG	PTGER4	ENSG00000171522	-0.8152170398305745	[139]	[59]	-5	hSpCas9	negative selection	130666
40681820	40681843	5	-	26472758	Jiyoye	viability	GATGAGCACCACCAGGGAGGTGG	PTGER4	ENSG00000171522	0.37916100533627706	[51]	[50]	3	hSpCas9	negative selection	130667
40681068	40681091	5	+	26472758	KBM7	viability	GGTGATGTTCATCTTCGGGGTGG	PTGER4	ENSG00000171522	-0.6952492968466136	[487,163]	[140,44]	-5	hSpCas9	negative selection	321776
40681233	40681256	5	+	26472758	KBM7	viability	CATGAAGGGCCAATGGCCCGGGG	PTGER4	ENSG00000171522	-0.44673124630889705	[247,99]	[100,18]	-4	hSpCas9	negative selection	321777
40680998	40681021	5	-	26472758	KBM7	viability	GGACGAATTGACCCCGGGAGTGG	PTGER4	ENSG00000171522	0.22278254304606446	[531,250]	[198,215]	2	hSpCas9	negative selection	321778
40681022	40681045	5	-	26472758	KBM7	viability	CAGCCGGTCGGGGCTCAAGGAGG	PTGER4	ENSG00000171522	0.02708587279386787	[45,43]	[9,31]	0	hSpCas9	negative selection	321779
40681047	40681070	5	+	26472758	KBM7	viability	CAGCCCAGTGACCATCCCGGCGG	PTGER4	ENSG00000171522	-0.5989658134370088	[380,172]	[99,67]	-5	hSpCas9	negative selection	321780
40681143	40681166	5	+	26472758	KBM7	viability	GGAGACGACCTTCTACACGCTGG	PTGER4	ENSG00000171522	0.3625400493630062	[180,202]	[101,130]	4	hSpCas9	negative selection	321781
40681261	40681284	5	-	26472758	KBM7	viability	AAGGTGCTGTACTCGCACAGCGG	PTGER4	ENSG00000171522	0.6602895390646036	[146,151]	[67,150]	7	hSpCas9	negative selection	321782
40681586	40681609	5	-	26472758	KBM7	viability	AAGCACGTTGCAGAGGACGGTGG	PTGER4	ENSG00000171522	-0.17658751479981083	[110,126]	[38,59]	-2	hSpCas9	negative selection	321783
40681727	40681750	5	-	26472758	KBM7	viability	GCTGAGGCGCGGCAAGGCTGGGG	PTGER4	ENSG00000171522	-0.056251003964366164	[359,397]	[208,140]	0	hSpCas9	negative selection	321784
40681820	40681843	5	-	26472758	KBM7	viability	GATGAGCACCACCAGGGAGGTGG	PTGER4	ENSG00000171522	-0.17936110733201768	[511,506]	[278,152]	-2	hSpCas9	negative selection	321785
40681068	40681091	5	+	26472758	Raji	viability	GGTGATGTTCATCTTCGGGGTGG	PTGER4	ENSG00000171522	-0.18212308182138526	[131]	[26]	-1	hSpCas9	negative selection	512894
40681233	40681256	5	+	26472758	Raji	viability	CATGAAGGGCCAATGGCCCGGGG	PTGER4	ENSG00000171522	0.29475367127532104	[136]	[38]	2	hSpCas9	negative selection	512895
40680998	40681021	5	-	26472758	Raji	viability	GGACGAATTGACCCCGGGAGTGG	PTGER4	ENSG00000171522	-0.5330740779392603	[211]	[33]	-4	hSpCas9	negative selection	512896
40681022	40681045	5	-	26472758	Raji	viability	CAGCCGGTCGGGGCTCAAGGAGG	PTGER4	ENSG00000171522	0.7114548590424603	[49]	[18]	6	hSpCas9	negative selection	512897
40681047	40681070	5	+	26472758	Raji	viability	CAGCCCAGTGACCATCCCGGCGG	PTGER4	ENSG00000171522	1.172971877001176	[85]	[44]	8	hSpCas9	negative selection	512898
40681143	40681166	5	+	26472758	Raji	viability	GGAGACGACCTTCTACACGCTGG	PTGER4	ENSG00000171522	-0.5466206097772079	[106]	[16]	-4	hSpCas9	negative selection	512899
40681261	40681284	5	-	26472758	Raji	viability	AAGGTGCTGTACTCGCACAGCGG	PTGER4	ENSG00000171522	0.4069438172325075	[142]	[43]	4	hSpCas9	negative selection	512900
40681586	40681609	5	-	26472758	Raji	viability	AAGCACGTTGCAGAGGACGGTGG	PTGER4	ENSG00000171522	3.387491454566335	[20]	[50]	9	hSpCas9	negative selection	512901
40681727	40681750	5	-	26472758	Raji	viability	GCTGAGGCGCGGCAAGGCTGGGG	PTGER4	ENSG00000171522	0.7088341588833246	[115]	[43]	6	hSpCas9	negative selection	512902
40681820	40681843	5	-	26472758	Raji	viability	GATGAGCACCACCAGGGAGGTGG	PTGER4	ENSG00000171522	-1.250168469244484	[245]	[23]	-7	hSpCas9	negative selection	512903
40681068	40681091	5	+	26472758	K562	viability	GGTGATGTTCATCTTCGGGGTGG	PTGER4	ENSG00000171522	-0.43630275586014	[217]	[135]	-3	hSpCas9	negative selection	704012
40681233	40681256	5	+	26472758	K562	viability	CATGAAGGGCCAATGGCCCGGGG	PTGER4	ENSG00000171522	0.9514828361187913	[116]	[190]	7	hSpCas9	negative selection	704013
40680998	40681021	5	-	26472758	K562	viability	GGACGAATTGACCCCGGGAGTGG	PTGER4	ENSG00000171522	1.2191680505510414	[316]	[622]	8	hSpCas9	negative selection	704014
40681022	40681045	5	-	26472758	K562	viability	CAGCCGGTCGGGGCTCAAGGAGG	PTGER4	ENSG00000171522	-0.893084796083488	[21]	[9]	-5	hSpCas9	negative selection	704015
40681047	40681070	5	+	26472758	K562	viability	CAGCCCAGTGACCATCCCGGCGG	PTGER4	ENSG00000171522	-0.4123765178157761	[174]	[110]	-3	hSpCas9	negative selection	704016
40681143	40681166	5	+	26472758	K562	viability	GGAGACGACCTTCTACACGCTGG	PTGER4	ENSG00000171522	0.19449350233476448	[146]	[141]	1	hSpCas9	negative selection	704017
40681261	40681284	5	-	26472758	K562	viability	AAGGTGCTGTACTCGCACAGCGG	PTGER4	ENSG00000171522	0.08944406769010593	[215]	[193]	0	hSpCas9	negative selection	704018
40681586	40681609	5	-	26472758	K562	viability	AAGCACGTTGCAGAGGACGGTGG	PTGER4	ENSG00000171522	-0.1622065317961967	[56]	[42]	-1	hSpCas9	negative selection	704019
40681727	40681750	5	-	26472758	K562	viability	GCTGAGGCGCGGCAAGGCTGGGG	PTGER4	ENSG00000171522	-1.761681471869971	[236]	[58]	-7	hSpCas9	negative selection	704020
40681820	40681843	5	-	26472758	K562	viability	GATGAGCACCACCAGGGAGGTGG	PTGER4	ENSG00000171522	-1.168520305728399	[457]	[171]	-6	hSpCas9	negative selection	704021
40681231	40681254	5	+	26627737	DLD1	viability	TACATGAAGGGCCAATGGCCCGG	PTGER4	ENSG00000171522	0.3651311463314939	[178]	[68,49,92]	4	hSpCas9	negative selection	828801
40681359	40681382	5	-	26627737	DLD1	viability	AGTGGCTGTAGAAATAGGCATGG	PTGER4	ENSG00000171522	0.6863901042394102	[289]	[90,143,194]	6	hSpCas9	negative selection	828802
40681589	40681612	5	-	26627737	DLD1	viability	CACAAGCACGTTGCAGAGGACGG	PTGER4	ENSG00000171522	-0.17324185229847067	[1026]	[552,296,41]	-2	hSpCas9	negative selection	828803
40681745	40681768	5	+	26627737	DLD1	viability	TCAGCGACTTTCGGCGCCGCCGG	PTGER4	ENSG00000171522	1.15217040994111	[230]	[108,191,178]	9	hSpCas9	negative selection	828804
40691901	40691924	5	-	26627737	DLD1	viability	TGAGCACTGTCTTTCTCAGGAGG	PTGER4	ENSG00000171522	0.3964161758747873	[203]	[84,60,101]	4	hSpCas9	negative selection	828805
40681231	40681254	5	+	26627737	GBM cells	viability after 5 days	TACATGAAGGGCCAATGGCCCGG	PTGER4	ENSG00000171522	0.3615408326827898	[81]	[51,60]	5	hSpCas9	negative selection	911116
40681359	40681382	5	-	26627737	GBM cells	viability after 5 days	AGTGGCTGTAGAAATAGGCATGG	PTGER4	ENSG00000171522	1.0523883555474038	[97]	[105,111]	9	hSpCas9	negative selection	911117
40681589	40681612	5	-	26627737	GBM cells	viability after 5 days	CACAAGCACGTTGCAGAGGACGG	PTGER4	ENSG00000171522	0.20522098918517861	[519]	[278,363]	3	hSpCas9	negative selection	911118
40681745	40681768	5	+	26627737	GBM cells	viability after 5 days	TCAGCGACTTTCGGCGCCGCCGG	PTGER4	ENSG00000171522	-0.3262609871220895	[172]	[94,52]	-5	hSpCas9	negative selection	911119
40691901	40691924	5	-	26627737	GBM cells	viability after 5 days	TGAGCACTGTCTTTCTCAGGAGG	PTGER4	ENSG00000171522	-0.19369727529918945	[192]	[82,97]	-3	hSpCas9	negative selection	911120
40681231	40681254	5	+	26627737	GBM cells	viability after 13 days	TACATGAAGGGCCAATGGCCCGG	PTGER4	ENSG00000171522	-0.32929204553027347	[81]	[30,38]	-4	hSpCas9	negative selection	993431
40681359	40681382	5	-	26627737	GBM cells	viability after 13 days	AGTGGCTGTAGAAATAGGCATGG	PTGER4	ENSG00000171522	0.9703807590846212	[97]	[128,83]	9	hSpCas9	negative selection	993432
40681589	40681612	5	-	26627737	GBM cells	viability after 13 days	CACAAGCACGTTGCAGAGGACGG	PTGER4	ENSG00000171522	0.49443960908150597	[519]	[445,357]	6	hSpCas9	negative selection	993433
40681745	40681768	5	+	26627737	GBM cells	viability after 13 days	TCAGCGACTTTCGGCGCCGCCGG	PTGER4	ENSG00000171522	-0.40681768292591136	[172]	[88,55]	-5	hSpCas9	negative selection	993434
40691901	40691924	5	-	26627737	GBM cells	viability after 13 days	TGAGCACTGTCTTTCTCAGGAGG	PTGER4	ENSG00000171522	0.06559520400166535	[192]	[113,105]	0	hSpCas9	negative selection	993435
40681231	40681254	5	+	26627737	GBM cells	viability after 21 days	TACATGAAGGGCCAATGGCCCGG	PTGER4	ENSG00000171522	1.6920495937353568	[81]	[156,131]	9	hSpCas9	negative selection	1075746
40681359	40681382	5	-	26627737	GBM cells	viability after 21 days	AGTGGCTGTAGAAATAGGCATGG	PTGER4	ENSG00000171522	0.8175520668595234	[97]	[85,100]	7	hSpCas9	negative selection	1075747
40681589	40681612	5	-	26627737	GBM cells	viability after 21 days	CACAAGCACGTTGCAGAGGACGG	PTGER4	ENSG00000171522	0.6385328318340444	[519]	[432,445]	6	hSpCas9	negative selection	1075748
40681745	40681768	5	+	26627737	GBM cells	viability after 21 days	TCAGCGACTTTCGGCGCCGCCGG	PTGER4	ENSG00000171522	-0.13111557540009067	[172]	[89,81]	-1	hSpCas9	negative selection	1075749
40691901	40691924	5	-	26627737	GBM cells	viability after 21 days	TGAGCACTGTCTTTCTCAGGAGG	PTGER4	ENSG00000171522	-0.5398517931441679	[192]	[80,63]	-5	hSpCas9	negative selection	1075750
40681231	40681254	5	+	26627737	RPE1	viability after 9 days	TACATGAAGGGCCAATGGCCCGG	PTGER4	ENSG00000171522	1.9206343638640324	[117]	[162,109]	8	hSpCas9	negative selection	1158061
40681359	40681382	5	-	26627737	RPE1	viability after 9 days	AGTGGCTGTAGAAATAGGCATGG	PTGER4	ENSG00000171522	0.12589099504325388	[906]	[263,368]	0	hSpCas9	negative selection	1158062
40681589	40681612	5	-	26627737	RPE1	viability after 9 days	CACAAGCACGTTGCAGAGGACGG	PTGER4	ENSG00000171522	0.9677709884036181	[1559]	[618,1388]	6	hSpCas9	negative selection	1158063
40681745	40681768	5	+	26627737	RPE1	viability after 9 days	TCAGCGACTTTCGGCGCCGCCGG	PTGER4	ENSG00000171522	-0.23898264288764665	[628]	[158,176]	-2	hSpCas9	negative selection	1158064
40691901	40691924	5	-	26627737	RPE1	viability after 9 days	TGAGCACTGTCTTTCTCAGGAGG	PTGER4	ENSG00000171522	-2.502712935230195	[1563]	[95,73]	-9	hSpCas9	negative selection	1158065
40681231	40681254	5	+	26627737	RPE1	viability after 12 days	TACATGAAGGGCCAATGGCCCGG	PTGER4	ENSG00000171522	1.8771236815321437	[117]	[165,63]	8	hSpCas9	negative selection	1240376
40681359	40681382	5	-	26627737	RPE1	viability after 12 days	AGTGGCTGTAGAAATAGGCATGG	PTGER4	ENSG00000171522	-0.020411816046700892	[906]	[248,230]	0	hSpCas9	negative selection	1240377
40681589	40681612	5	-	26627737	RPE1	viability after 12 days	CACAAGCACGTTGCAGAGGACGG	PTGER4	ENSG00000171522	0.9773311567026806	[1559]	[507,1160]	6	hSpCas9	negative selection	1240378
40681745	40681768	5	+	26627737	RPE1	viability after 12 days	TCAGCGACTTTCGGCGCCGCCGG	PTGER4	ENSG00000171522	0.7898664985358255	[628]	[246,339]	5	hSpCas9	negative selection	1240379
40691901	40691924	5	-	26627737	RPE1	viability after 12 days	TGAGCACTGTCTTTCTCAGGAGG	PTGER4	ENSG00000171522	-2.973831682995776	[1563]	[52,53]	-9	hSpCas9	negative selection	1240380
40681231	40681254	5	+	26627737	RPE1	viability after 15 days	TACATGAAGGGCCAATGGCCCGG	PTGER4	ENSG00000171522	2.0838102011050785	[117]	[84,195]	8	hSpCas9	negative selection	1322691
40681359	40681382	5	-	26627737	RPE1	viability after 15 days	AGTGGCTGTAGAAATAGGCATGG	PTGER4	ENSG00000171522	0.1156959824434027	[906]	[193,358]	0	hSpCas9	negative selection	1322692
40681589	40681612	5	-	26627737	RPE1	viability after 15 days	CACAAGCACGTTGCAGAGGACGG	PTGER4	ENSG00000171522	0.9710088431060433	[1559]	[666,1055]	6	hSpCas9	negative selection	1322693
40681745	40681768	5	+	26627737	RPE1	viability after 15 days	TCAGCGACTTTCGGCGCCGCCGG	PTGER4	ENSG00000171522	-0.17161384434415178	[628]	[74,237]	-1	hSpCas9	negative selection	1322694
40691901	40691924	5	-	26627737	RPE1	viability after 15 days	TGAGCACTGTCTTTCTCAGGAGG	PTGER4	ENSG00000171522	-2.963331477421371	[1563]	[43,68]	-9	hSpCas9	negative selection	1322695
40681231	40681254	5	+	26627737	RPE1	viability after 18 days	TACATGAAGGGCCAATGGCCCGG	PTGER4	ENSG00000171522	1.5791821126792127	[117]	[84,105]	8	hSpCas9	negative selection	1405006
40681359	40681382	5	-	26627737	RPE1	viability after 18 days	AGTGGCTGTAGAAATAGGCATGG	PTGER4	ENSG00000171522	0.34690862460222005	[906]	[261,363]	2	hSpCas9	negative selection	1405007
40681589	40681612	5	-	26627737	RPE1	viability after 18 days	CACAAGCACGTTGCAGAGGACGG	PTGER4	ENSG00000171522	1.1265491308943516	[1559]	[603,1255]	6	hSpCas9	negative selection	1405008
40681745	40681768	5	+	26627737	RPE1	viability after 18 days	TCAGCGACTTTCGGCGCCGCCGG	PTGER4	ENSG00000171522	0.12121079323897493	[628]	[129,242]	0	hSpCas9	negative selection	1405009
40691901	40691924	5	-	26627737	RPE1	viability after 18 days	TGAGCACTGTCTTTCTCAGGAGG	PTGER4	ENSG00000171522	-2.105461097796142	[1563]	[114,79]	-8	hSpCas9	negative selection	1405010
40681231	40681254	5	+	26627737	HeLa	viability after 8 days	TACATGAAGGGCCAATGGCCCGG	PTGER4	ENSG00000171522	-0.38902712306853804	[211]	[98,38,78]	-4	hSpCas9	negative selection	1487321
40681359	40681382	5	-	26627737	HeLa	viability after 8 days	AGTGGCTGTAGAAATAGGCATGG	PTGER4	ENSG00000171522	1.1768543869794346	[138]	[148,68,190]	8	hSpCas9	negative selection	1487322
40681589	40681612	5	-	26627737	HeLa	viability after 8 days	CACAAGCACGTTGCAGAGGACGG	PTGER4	ENSG00000171522	-1.0968147442615181	[1398]	[288,268,295]	-8	hSpCas9	negative selection	1487323
40681745	40681768	5	+	26627737	HeLa	viability after 8 days	TCAGCGACTTTCGGCGCCGCCGG	PTGER4	ENSG00000171522	-0.9324333315165013	[507]	[143,157,55]	-7	hSpCas9	negative selection	1487324
40691901	40691924	5	-	26627737	HeLa	viability after 8 days	TGAGCACTGTCTTTCTCAGGAGG	PTGER4	ENSG00000171522	-0.09824364762407212	[253]	[145,37,132]	-1	hSpCas9	negative selection	1487325
40681231	40681254	5	+	26627737	HeLa	viability after 12 days	TACATGAAGGGCCAATGGCCCGG	PTGER4	ENSG00000171522	0.5917119557854091	[211]	[223,44,138]	5	hSpCas9	negative selection	1569636
40681359	40681382	5	-	26627737	HeLa	viability after 12 days	AGTGGCTGTAGAAATAGGCATGG	PTGER4	ENSG00000171522	1.8330091461280715	[138]	[326,171,121]	9	hSpCas9	negative selection	1569637
40681589	40681612	5	-	26627737	HeLa	viability after 12 days	CACAAGCACGTTGCAGAGGACGG	PTGER4	ENSG00000171522	-1.0028196779021543	[1398]	[389,245,236]	-7	hSpCas9	negative selection	1569638
40681745	40681768	5	+	26627737	HeLa	viability after 12 days	TCAGCGACTTTCGGCGCCGCCGG	PTGER4	ENSG00000171522	-0.37366567187867955	[507]	[163,172,147]	-3	hSpCas9	negative selection	1569639
40691901	40691924	5	-	26627737	HeLa	viability after 12 days	TGAGCACTGTCTTTCTCAGGAGG	PTGER4	ENSG00000171522	-1.0573483426692605	[253]	[100,38,13]	-7	hSpCas9	negative selection	1569640
40681231	40681254	5	+	26627737	HeLa	viability after 15 days	TACATGAAGGGCCAATGGCCCGG	PTGER4	ENSG00000171522	-0.4424919914721466	[211]	[58,50,81]	-4	hSpCas9	negative selection	1651951
40681359	40681382	5	-	26627737	HeLa	viability after 15 days	AGTGGCTGTAGAAATAGGCATGG	PTGER4	ENSG00000171522	1.2122734187830846	[138]	[120,134,137]	8	hSpCas9	negative selection	1651952
40681589	40681612	5	-	26627737	HeLa	viability after 15 days	CACAAGCACGTTGCAGAGGACGG	PTGER4	ENSG00000171522	-0.6429295494749396	[1398]	[500,352,227]	-5	hSpCas9	negative selection	1651953
40681745	40681768	5	+	26627737	HeLa	viability after 15 days	TCAGCGACTTTCGGCGCCGCCGG	PTGER4	ENSG00000171522	0.10418341669229658	[507]	[296,193,170]	0	hSpCas9	negative selection	1651954
40691901	40691924	5	-	26627737	HeLa	viability after 15 days	TGAGCACTGTCTTTCTCAGGAGG	PTGER4	ENSG00000171522	-1.1660868091332497	[253]	[3,73,61]	-8	hSpCas9	negative selection	1651955
40681231	40681254	5	+	26627737	HeLa	viability after 18 days	TACATGAAGGGCCAATGGCCCGG	PTGER4	ENSG00000171522	-0.4189836601878758	[211]	[44,37,81]	-4	hSpCas9	negative selection	1734266
40681359	40681382	5	-	26627737	HeLa	viability after 18 days	AGTGGCTGTAGAAATAGGCATGG	PTGER4	ENSG00000171522	1.2053905306865984	[138]	[78,112,137]	8	hSpCas9	negative selection	1734267
40681589	40681612	5	-	26627737	HeLa	viability after 18 days	CACAAGCACGTTGCAGAGGACGG	PTGER4	ENSG00000171522	-0.5953056366737424	[1398]	[356,295,227]	-5	hSpCas9	negative selection	1734268
40681745	40681768	5	+	26627737	HeLa	viability after 18 days	TCAGCGACTTTCGGCGCCGCCGG	PTGER4	ENSG00000171522	0.10955525376135122	[507]	[194,167,170]	1	hSpCas9	negative selection	1734269
40691901	40691924	5	-	26627737	HeLa	viability after 18 days	TGAGCACTGTCTTTCTCAGGAGG	PTGER4	ENSG00000171522	-1.0893437137532838	[253]	[2,66,61]	-7	hSpCas9	negative selection	1734270
40681231	40681254	5	+	26627737	HCT116	viability after 6 days	TACATGAAGGGCCAATGGCCCGG	PTGER4	ENSG00000171522	1.161532807024627	[158]	[33,67]	6	hSpCas9	negative selection	1816581
40681359	40681382	5	-	26627737	HCT116	viability after 6 days	AGTGGCTGTAGAAATAGGCATGG	PTGER4	ENSG00000171522	-1.3124853079992356	[829]	[38,59]	-6	hSpCas9	negative selection	1816582
40681589	40681612	5	-	26627737	HCT116	viability after 6 days	CACAAGCACGTTGCAGAGGACGG	PTGER4	ENSG00000171522	0.38129306664027407	[1276]	[158,317]	2	hSpCas9	negative selection	1816583
40681745	40681768	5	+	26627737	HCT116	viability after 6 days	TCAGCGACTTTCGGCGCCGCCGG	PTGER4	ENSG00000171522	0.5499849059234492	[559]	[251,60]	3	hSpCas9	negative selection	1816584
40691901	40691924	5	-	26627737	HCT116	viability after 6 days	TGAGCACTGTCTTTCTCAGGAGG	PTGER4	ENSG00000171522	-0.26216163941188664	[260]	[88,3]	-1	hSpCas9	negative selection	1816585
40681231	40681254	5	+	26627737	HCT116	viability after 8 days	TACATGAAGGGCCAATGGCCCGG	PTGER4	ENSG00000171522	0.8333456343721746	[54]	[44,75,40]	7	hSpCas9	negative selection	1898896
40681359	40681382	5	-	26627737	HCT116	viability after 8 days	AGTGGCTGTAGAAATAGGCATGG	PTGER4	ENSG00000171522	0.0487609651075353	[411]	[173,261,266]	0	hSpCas9	negative selection	1898897
40681589	40681612	5	-	26627737	HCT116	viability after 8 days	CACAAGCACGTTGCAGAGGACGG	PTGER4	ENSG00000171522	0.24267322276772296	[532]	[410,315,316]	2	hSpCas9	negative selection	1898898
40681745	40681768	5	+	26627737	HCT116	viability after 8 days	TCAGCGACTTTCGGCGCCGCCGG	PTGER4	ENSG00000171522	1.8775644967591891	[70]	[89,252,87]	9	hSpCas9	negative selection	1898899
40691901	40691924	5	-	26627737	HCT116	viability after 8 days	TGAGCACTGTCTTTCTCAGGAGG	PTGER4	ENSG00000171522	-1.4558641592148764	[455]	[91,107,74]	-9	hSpCas9	negative selection	1898900
40681231	40681254	5	+	26627737	HCT116	viability after 9 days	TACATGAAGGGCCAATGGCCCGG	PTGER4	ENSG00000171522	2.3754738388699974	[158]	[307,150]	9	hSpCas9	negative selection	1981211
40681359	40681382	5	-	26627737	HCT116	viability after 9 days	AGTGGCTGTAGAAATAGGCATGG	PTGER4	ENSG00000171522	-0.12728219855882494	[829]	[260,156]	-1	hSpCas9	negative selection	1981212
40681589	40681612	5	-	26627737	HCT116	viability after 9 days	CACAAGCACGTTGCAGAGGACGG	PTGER4	ENSG00000171522	0.3107764847971666	[1276]	[556,316]	2	hSpCas9	negative selection	1981213
40681745	40681768	5	+	26627737	HCT116	viability after 9 days	TCAGCGACTTTCGGCGCCGCCGG	PTGER4	ENSG00000171522	-0.8221069454184334	[559]	[121,54]	-5	hSpCas9	negative selection	1981214
40691901	40691924	5	-	26627737	HCT116	viability after 9 days	TGAGCACTGTCTTTCTCAGGAGG	PTGER4	ENSG00000171522	1.1133350846804198	[260]	[109,182]	7	hSpCas9	negative selection	1981215
40681231	40681254	5	+	26627737	HCT116	viability after 12 days	TACATGAAGGGCCAATGGCCCGG	PTGER4	ENSG00000171522	1.1117271819159071	[54]	[81,75,27]	8	hSpCas9	negative selection	2063526
40681359	40681382	5	-	26627737	HCT116	viability after 12 days	AGTGGCTGTAGAAATAGGCATGG	PTGER4	ENSG00000171522	-0.48443799534699555	[411]	[132,187,145]	-5	hSpCas9	negative selection	2063527
40681589	40681612	5	-	26627737	HCT116	viability after 12 days	CACAAGCACGTTGCAGAGGACGG	PTGER4	ENSG00000171522	-0.1551740164999329	[532]	[217,227,310]	-2	hSpCas9	negative selection	2063528
40681745	40681768	5	+	26627737	HCT116	viability after 12 days	TCAGCGACTTTCGGCGCCGCCGG	PTGER4	ENSG00000171522	2.128407084805835	[70]	[81,263,152]	9	hSpCas9	negative selection	2063529
40691901	40691924	5	-	26627737	HCT116	viability after 12 days	TGAGCACTGTCTTTCTCAGGAGG	PTGER4	ENSG00000171522	-1.1522783726597288	[455]	[76,59,187]	-8	hSpCas9	negative selection	2063530
40681231	40681254	5	+	26627737	HCT116	viability after 15 days	TACATGAAGGGCCAATGGCCCGG	PTGER4	ENSG00000171522	0.9566342608611549	[54]	[85,46,53]	7	hSpCas9	negative selection	2145841
40681359	40681382	5	-	26627737	HCT116	viability after 15 days	AGTGGCTGTAGAAATAGGCATGG	PTGER4	ENSG00000171522	-0.3136719087823474	[411]	[171,215,180]	-3	hSpCas9	negative selection	2145842
40681589	40681612	5	-	26627737	HCT116	viability after 15 days	CACAAGCACGTTGCAGAGGACGG	PTGER4	ENSG00000171522	-0.32150604141505423	[532]	[214,253,261]	-3	hSpCas9	negative selection	2145843
40681745	40681768	5	+	26627737	HCT116	viability after 15 days	TCAGCGACTTTCGGCGCCGCCGG	PTGER4	ENSG00000171522	2.1956164592277587	[70]	[129,199,222]	9	hSpCas9	negative selection	2145844
40691901	40691924	5	-	26627737	HCT116	viability after 15 days	TGAGCACTGTCTTTCTCAGGAGG	PTGER4	ENSG00000171522	-1.2310553086105203	[455]	[69,95,162]	-8	hSpCas9	negative selection	2145845
40681231	40681254	5	+	26627737	HCT116	viability after 18 days	TACATGAAGGGCCAATGGCCCGG	PTGER4	ENSG00000171522	0.6313843454650683	[54]	[40,28,54]	5	hSpCas9	negative selection	2228156
40681359	40681382	5	-	26627737	HCT116	viability after 18 days	AGTGGCTGTAGAAATAGGCATGG	PTGER4	ENSG00000171522	-0.44971703459721063	[411]	[103,175,155]	-4	hSpCas9	negative selection	2228157
40681589	40681612	5	-	26627737	HCT116	viability after 18 days	CACAAGCACGTTGCAGAGGACGG	PTGER4	ENSG00000171522	-0.13384733393858206	[532]	[288,242,168]	-1	hSpCas9	negative selection	2228158
40681745	40681768	5	+	26627737	HCT116	viability after 18 days	TCAGCGACTTTCGGCGCCGCCGG	PTGER4	ENSG00000171522	1.6218110421797636	[70]	[108,94,113]	9	hSpCas9	negative selection	2228159
40691901	40691924	5	-	26627737	HCT116	viability after 18 days	TGAGCACTGTCTTTCTCAGGAGG	PTGER4	ENSG00000171522	-1.7994565262287665	[455]	[59,38,93]	-8	hSpCas9	negative selection	2228160
40679834	40679857	5	+	25494202	A375	resistance to PLX-4720 (puromycin)	AATCCGGCCAATGGGCGCCCGGG	PTGER4	ENSG00000171522	-2.352338191815607	[58,373]	[7,9]	-9	dCas9-VP64	positive selection	2384998
40679788	40679811	5	+	25494202	A375	resistance to PLX-4720 (puromycin)	CAGTCTTCCCTGCGGCGCCCAGG	PTGER4	ENSG00000171522	0.6593177756185676	[60,59]	[3,38]	3	dCas9-VP64	positive selection	2384999
40679764	40679787	5	-	25494202	A375	resistance to PLX-4720 (puromycin)	CGGGGGGCGGTGTCTGGGCTGGG	PTGER4	ENSG00000171522	0.44967144738055875	[5,7]	[1,1]	2	dCas9-VP64	positive selection	2385000
40679834	40679857	5	+	25494202	A375	resistance to PLX-4720 (zeocin)	AATCCGGCCAATGGGCGCCCGGG	PTGER4	ENSG00000171522	-1.315556046699411	[241,132]	[32,15]	-9	dCas9-VP64	positive selection	2480253
40679788	40679811	5	+	25494202	A375	resistance to PLX-4720 (zeocin)	CAGTCTTCCCTGCGGCGCCCAGG	PTGER4	ENSG00000171522	1.5408385501520865	[103,88]	[38,141]	8	dCas9-VP64	positive selection	2480254
40679764	40679787	5	-	25494202	A375	resistance to PLX-4720 (zeocin)	CGGGGGGCGGTGTCTGGGCTGGG	PTGER4	ENSG00000171522	1.568241810900851	[8,48]	[7,45]	8	dCas9-VP64	positive selection	2480255
40681377	40681400	5	+	27260157	DLD1	viability	CCACTACGTGGACAAGCGATTGG	PTGER4	ENSG00000171522	0.165078131853364	[]	[]	3	hSpCas9	negative selection	2576163
40681155	40681178	5	+	27260157	DLD1	viability	CTACACGCTGGTATGTGGGCTGG	PTGER4	ENSG00000171522	-0.724846528563427	[]	[]	-5	hSpCas9	negative selection	2579854
40681493	40681516	5	+	27260157	DLD1	viability	ACACCTGGTGCTTCATCGACTGG	PTGER4	ENSG00000171522	1.0745383536138	[]	[]	9	hSpCas9	negative selection	2580773
40681626	40681649	5	-	27260157	DLD1	viability	GCATGAACTGGCGGTGCATGCGG	PTGER4	ENSG00000171522	0.237019330766553	[]	[]	4	hSpCas9	negative selection	2581811
40681185	40681208	5	+	27260157	DLD1	viability	CGACCTGTTGGGCACTTTGTTGG	PTGER4	ENSG00000171522	-0.395308098740515	[]	[]	-3	hSpCas9	negative selection	2582252
40681032	40681055	5	-	27260157	DLD1	viability	CTGGGCTGTTCAGCCGGTCGGGG	PTGER4	ENSG00000171522	0.256172876449944	[]	[]	4	hSpCas9	negative selection	2584617
40681517	40681540	5	-	27260157	DLD1	viability	GGCGTGCGCCGTCACGTTGGTGG	PTGER4	ENSG00000171522	-2.67156418343005	[]	[]	-9	hSpCas9	negative selection	2586327
40681488	40681511	5	-	27260157	DLD1	viability	CGATGAAGCACCAGGTGTCTGGG	PTGER4	ENSG00000171522	-0.289657824097811	[]	[]	-2	hSpCas9	negative selection	2606021
40681571	40681594	5	-	27260157	DLD1	viability	GACGGTGGCGAGAATGAGGAAGG	PTGER4	ENSG00000171522	0.506615646116205	[]	[]	8	hSpCas9	negative selection	2609248
40681231	40681254	5	+	27260157	DLD1	viability	TACATGAAGGGCCAATGGCCCGG	PTGER4	ENSG00000171522	0.486779714315014	[]	[]	8	hSpCas9	negative selection	2611739
40681143	40681166	5	+	27260157	DLD1	viability	GGAGACGACCTTCTACACGCTGG	PTGER4	ENSG00000171522	0.104967582685366	[]	[]	3	hSpCas9	negative selection	2612070
40681594	40681617	5	+	27260157	DLD1	viability	CTCTGCAACGTGCTTGTGTGCGG	PTGER4	ENSG00000171522	-0.708068026338431	[]	[]	-5	hSpCas9	negative selection	2612449
40681004	40681027	5	-	27260157	DLD1	viability	GGAGGCGGACGAATTGACCCCGG	PTGER4	ENSG00000171522	-0.249891305558646	[]	[]	-2	hSpCas9	negative selection	2616424
40681050	40681073	5	-	27260157	DLD1	viability	TCACCGCCGGGATGGTCACTGGG	PTGER4	ENSG00000171522	-0.041327465587313	[]	[]	0	hSpCas9	negative selection	2616985
40681347	40681370	5	-	27260157	DLD1	viability	AATAGGCATGGTTGATGGCCAGG	PTGER4	ENSG00000171522	0.00574899054896675	[]	[]	0	hSpCas9	negative selection	2619193
40681509	40681532	5	+	27260157	DLD1	viability	CGACTGGACCACCAACGTGACGG	PTGER4	ENSG00000171522	0.837537636317099	[]	[]	9	hSpCas9	negative selection	2623608
40681377	40681400	5	-	27260157	DLD1	viability	CCAATCGCTTGTCCACGTAGTGG	PTGER4	ENSG00000171522	-0.612535747135219	[]	[]	-5	hSpCas9	negative selection	2642160
40681226	40681249	5	-	27260157	DLD1	viability	CCATTGGCCCTTCATGTACGTGG	PTGER4	ENSG00000171522	0.429962626783755	[]	[]	7	hSpCas9	negative selection	2644140
40681539	40681562	5	+	27260157	DLD1	viability	CGCCTACTCCTACATGTACGCGG	PTGER4	ENSG00000171522	-1.14073238567553	[]	[]	-7	hSpCas9	negative selection	2645050
40681447	40681470	5	+	27260157	DLD1	viability	GCGCTGCCCAACATGGGTCTCGG	PTGER4	ENSG00000171522	-0.780953105997429	[]	[]	-6	hSpCas9	negative selection	2649052
40681377	40681400	5	+	27260157	HT1080	viability	CCACTACGTGGACAAGCGATTGG	PTGER4	ENSG00000171522	1.02682357208255	[]	[]	8	hSpCas9	negative selection	2652293
40681155	40681178	5	+	27260157	HT1080	viability	CTACACGCTGGTATGTGGGCTGG	PTGER4	ENSG00000171522	0.32550888522049	[]	[]	3	hSpCas9	negative selection	2655984
40681493	40681516	5	+	27260157	HT1080	viability	ACACCTGGTGCTTCATCGACTGG	PTGER4	ENSG00000171522	0.694219126375112	[]	[]	6	hSpCas9	negative selection	2656903
40681626	40681649	5	-	27260157	HT1080	viability	GCATGAACTGGCGGTGCATGCGG	PTGER4	ENSG00000171522	-0.0853224566375945	[]	[]	0	hSpCas9	negative selection	2657941
40681185	40681208	5	+	27260157	HT1080	viability	CGACCTGTTGGGCACTTTGTTGG	PTGER4	ENSG00000171522	-0.580598160209462	[]	[]	-7	hSpCas9	negative selection	2658382
40681032	40681055	5	-	27260157	HT1080	viability	CTGGGCTGTTCAGCCGGTCGGGG	PTGER4	ENSG00000171522	-0.273475638619156	[]	[]	-4	hSpCas9	negative selection	2660747
40681517	40681540	5	-	27260157	HT1080	viability	GGCGTGCGCCGTCACGTTGGTGG	PTGER4	ENSG00000171522	-3.38676949244428	[]	[]	-9	hSpCas9	negative selection	2662457
40681488	40681511	5	-	27260157	HT1080	viability	CGATGAAGCACCAGGTGTCTGGG	PTGER4	ENSG00000171522	1.64648531774417	[]	[]	9	hSpCas9	negative selection	2682151
40681571	40681594	5	-	27260157	HT1080	viability	GACGGTGGCGAGAATGAGGAAGG	PTGER4	ENSG00000171522	1.97932270362286	[]	[]	9	hSpCas9	negative selection	2685378
40681231	40681254	5	+	27260157	HT1080	viability	TACATGAAGGGCCAATGGCCCGG	PTGER4	ENSG00000171522	0.722414895832676	[]	[]	6	hSpCas9	negative selection	2687869
40681143	40681166	5	+	27260157	HT1080	viability	GGAGACGACCTTCTACACGCTGG	PTGER4	ENSG00000171522	0.472745765374428	[]	[]	4	hSpCas9	negative selection	2688200
40681594	40681617	5	+	27260157	HT1080	viability	CTCTGCAACGTGCTTGTGTGCGG	PTGER4	ENSG00000171522	0.323276549972301	[]	[]	3	hSpCas9	negative selection	2688579
40681004	40681027	5	-	27260157	HT1080	viability	GGAGGCGGACGAATTGACCCCGG	PTGER4	ENSG00000171522	0.968354975847008	[]	[]	7	hSpCas9	negative selection	2692554
40681050	40681073	5	-	27260157	HT1080	viability	TCACCGCCGGGATGGTCACTGGG	PTGER4	ENSG00000171522	0.35704081363303	[]	[]	3	hSpCas9	negative selection	2693115
40681347	40681370	5	-	27260157	HT1080	viability	AATAGGCATGGTTGATGGCCAGG	PTGER4	ENSG00000171522	0.223702501923825	[]	[]	2	hSpCas9	negative selection	2695323
40681509	40681532	5	+	27260157	HT1080	viability	CGACTGGACCACCAACGTGACGG	PTGER4	ENSG00000171522	0.846397075769007	[]	[]	7	hSpCas9	negative selection	2699738
40681377	40681400	5	-	27260157	HT1080	viability	CCAATCGCTTGTCCACGTAGTGG	PTGER4	ENSG00000171522	-0.204341657471199	[]	[]	0	hSpCas9	negative selection	2718290
40681226	40681249	5	-	27260157	HT1080	viability	CCATTGGCCCTTCATGTACGTGG	PTGER4	ENSG00000171522	0.105879658227255	[]	[]	1	hSpCas9	negative selection	2720270
40681539	40681562	5	+	27260157	HT1080	viability	CGCCTACTCCTACATGTACGCGG	PTGER4	ENSG00000171522	-0.63403704895958	[]	[]	-8	hSpCas9	negative selection	2721180
40681447	40681470	5	+	27260157	HT1080	viability	GCGCTGCCCAACATGGGTCTCGG	PTGER4	ENSG00000171522	-0.261583699466814	[]	[]	0	hSpCas9	negative selection	2725182
40681377	40681400	5	+	27260157	MKN45	viability	CCACTACGTGGACAAGCGATTGG	PTGER4	ENSG00000171522	0.302839500241282	[]	[]	5	hSpCas9	negative selection	2728423
40681155	40681178	5	+	27260157	MKN45	viability	CTACACGCTGGTATGTGGGCTGG	PTGER4	ENSG00000171522	-0.921086742445689	[]	[]	-7	hSpCas9	negative selection	2732114
40681493	40681516	5	+	27260157	MKN45	viability	ACACCTGGTGCTTCATCGACTGG	PTGER4	ENSG00000171522	0.343853927505732	[]	[]	6	hSpCas9	negative selection	2733033
40681626	40681649	5	-	27260157	MKN45	viability	GCATGAACTGGCGGTGCATGCGG	PTGER4	ENSG00000171522	0.207849726923063	[]	[]	5	hSpCas9	negative selection	2734071
40681185	40681208	5	+	27260157	MKN45	viability	CGACCTGTTGGGCACTTTGTTGG	PTGER4	ENSG00000171522	-1.22040639574013	[]	[]	-8	hSpCas9	negative selection	2734512
40681032	40681055	5	-	27260157	MKN45	viability	CTGGGCTGTTCAGCCGGTCGGGG	PTGER4	ENSG00000171522	-0.25266835324849	[]	[]	-1	hSpCas9	negative selection	2736877
40681517	40681540	5	-	27260157	MKN45	viability	GGCGTGCGCCGTCACGTTGGTGG	PTGER4	ENSG00000171522	-1.21947920011024	[]	[]	-8	hSpCas9	negative selection	2738587
40681488	40681511	5	-	27260157	MKN45	viability	CGATGAAGCACCAGGTGTCTGGG	PTGER4	ENSG00000171522	1.55089709745512	[]	[]	9	hSpCas9	negative selection	2758281
40681571	40681594	5	-	27260157	MKN45	viability	GACGGTGGCGAGAATGAGGAAGG	PTGER4	ENSG00000171522	1.11072460130817	[]	[]	8	hSpCas9	negative selection	2761508
40681231	40681254	5	+	27260157	MKN45	viability	TACATGAAGGGCCAATGGCCCGG	PTGER4	ENSG00000171522	0.313040536766455	[]	[]	5	hSpCas9	negative selection	2763999
40681143	40681166	5	+	27260157	MKN45	viability	GGAGACGACCTTCTACACGCTGG	PTGER4	ENSG00000171522	0.0361369461066662	[]	[]	0	hSpCas9	negative selection	2764330
40681594	40681617	5	+	27260157	MKN45	viability	CTCTGCAACGTGCTTGTGTGCGG	PTGER4	ENSG00000171522	-0.158857415641819	[]	[]	0	hSpCas9	negative selection	2764709
40681004	40681027	5	-	27260157	MKN45	viability	GGAGGCGGACGAATTGACCCCGG	PTGER4	ENSG00000171522	0.290735366341681	[]	[]	5	hSpCas9	negative selection	2768684
40681050	40681073	5	-	27260157	MKN45	viability	TCACCGCCGGGATGGTCACTGGG	PTGER4	ENSG00000171522	-0.936294822898732	[]	[]	-7	hSpCas9	negative selection	2769245
40681347	40681370	5	-	27260157	MKN45	viability	AATAGGCATGGTTGATGGCCAGG	PTGER4	ENSG00000171522	0.19014476210858	[]	[]	5	hSpCas9	negative selection	2771453
40681509	40681532	5	+	27260157	MKN45	viability	CGACTGGACCACCAACGTGACGG	PTGER4	ENSG00000171522	0.925369780386558	[]	[]	8	hSpCas9	negative selection	2775868
40681377	40681400	5	-	27260157	MKN45	viability	CCAATCGCTTGTCCACGTAGTGG	PTGER4	ENSG00000171522	-0.870994104947387	[]	[]	-7	hSpCas9	negative selection	2794420
40681226	40681249	5	-	27260157	MKN45	viability	CCATTGGCCCTTCATGTACGTGG	PTGER4	ENSG00000171522	1.06808735816721	[]	[]	8	hSpCas9	negative selection	2796400
40681539	40681562	5	+	27260157	MKN45	viability	CGCCTACTCCTACATGTACGCGG	PTGER4	ENSG00000171522	-0.824135394776431	[]	[]	-7	hSpCas9	negative selection	2797310
40681447	40681470	5	+	27260157	MKN45	viability	GCGCTGCCCAACATGGGTCTCGG	PTGER4	ENSG00000171522	-0.879753453040701	[]	[]	-7	hSpCas9	negative selection	2801312
40681377	40681400	5	+	27260157	RKO	viability	CCACTACGTGGACAAGCGATTGG	PTGER4	ENSG00000171522	0.641918513686597	[]	[]	3	hSpCas9	negative selection	2804553
40681155	40681178	5	+	27260157	RKO	viability	CTACACGCTGGTATGTGGGCTGG	PTGER4	ENSG00000171522	-0.185207176329513	[]	[]	-1	hSpCas9	negative selection	2808244
40681493	40681516	5	+	27260157	RKO	viability	ACACCTGGTGCTTCATCGACTGG	PTGER4	ENSG00000171522	1.00857414884967	[]	[]	9	hSpCas9	negative selection	2809163
40681626	40681649	5	-	27260157	RKO	viability	GCATGAACTGGCGGTGCATGCGG	PTGER4	ENSG00000171522	-0.339257513763399	[]	[]	-6	hSpCas9	negative selection	2810201
40681185	40681208	5	+	27260157	RKO	viability	CGACCTGTTGGGCACTTTGTTGG	PTGER4	ENSG00000171522	-0.49140197421919	[]	[]	-6	hSpCas9	negative selection	2810642
40681032	40681055	5	-	27260157	RKO	viability	CTGGGCTGTTCAGCCGGTCGGGG	PTGER4	ENSG00000171522	0.0495326287458264	[]	[]	0	hSpCas9	negative selection	2813007
40681517	40681540	5	-	27260157	RKO	viability	GGCGTGCGCCGTCACGTTGGTGG	PTGER4	ENSG00000171522	-0.86115483229099	[]	[]	-8	hSpCas9	negative selection	2814717
40681488	40681511	5	-	27260157	RKO	viability	CGATGAAGCACCAGGTGTCTGGG	PTGER4	ENSG00000171522	0.135429921527935	[]	[]	0	hSpCas9	negative selection	2834411
40681571	40681594	5	-	27260157	RKO	viability	GACGGTGGCGAGAATGAGGAAGG	PTGER4	ENSG00000171522	0.533610532524883	[]	[]	3	hSpCas9	negative selection	2837638
40681231	40681254	5	+	27260157	RKO	viability	TACATGAAGGGCCAATGGCCCGG	PTGER4	ENSG00000171522	1.00449315270561	[]	[]	9	hSpCas9	negative selection	2840129
40681143	40681166	5	+	27260157	RKO	viability	GGAGACGACCTTCTACACGCTGG	PTGER4	ENSG00000171522	0.433660244930616	[]	[]	2	hSpCas9	negative selection	2840460
40681594	40681617	5	+	27260157	RKO	viability	CTCTGCAACGTGCTTGTGTGCGG	PTGER4	ENSG00000171522	-0.313265738225173	[]	[]	-6	hSpCas9	negative selection	2840839
40681004	40681027	5	-	27260157	RKO	viability	GGAGGCGGACGAATTGACCCCGG	PTGER4	ENSG00000171522	0.17725087403598	[]	[]	0	hSpCas9	negative selection	2844814
40681050	40681073	5	-	27260157	RKO	viability	TCACCGCCGGGATGGTCACTGGG	PTGER4	ENSG00000171522	-0.837550262027556	[]	[]	-7	hSpCas9	negative selection	2845375
40681347	40681370	5	-	27260157	RKO	viability	AATAGGCATGGTTGATGGCCAGG	PTGER4	ENSG00000171522	0.164810473068349	[]	[]	0	hSpCas9	negative selection	2847583
40681509	40681532	5	+	27260157	RKO	viability	CGACTGGACCACCAACGTGACGG	PTGER4	ENSG00000171522	0.95616220060863	[]	[]	8	hSpCas9	negative selection	2851998
40681377	40681400	5	-	27260157	RKO	viability	CCAATCGCTTGTCCACGTAGTGG	PTGER4	ENSG00000171522	-0.266674515943789	[]	[]	-1	hSpCas9	negative selection	2870550
40681226	40681249	5	-	27260157	RKO	viability	CCATTGGCCCTTCATGTACGTGG	PTGER4	ENSG00000171522	0.598654087737735	[]	[]	3	hSpCas9	negative selection	2872530
40681539	40681562	5	+	27260157	RKO	viability	CGCCTACTCCTACATGTACGCGG	PTGER4	ENSG00000171522	-0.105303406946289	[]	[]	0	hSpCas9	negative selection	2873440
40681447	40681470	5	+	27260157	RKO	viability	GCGCTGCCCAACATGGGTCTCGG	PTGER4	ENSG00000171522	-0.575222335601952	[]	[]	-7	hSpCas9	negative selection	2877442
40681377	40681400	5	+	27260157	SF268	viability	CCACTACGTGGACAAGCGATTGG	PTGER4	ENSG00000171522	0.873884774915394	[]	[]	9	hSpCas9	negative selection	2880683
40681155	40681178	5	+	27260157	SF268	viability	CTACACGCTGGTATGTGGGCTGG	PTGER4	ENSG00000171522	0.0192843186847674	[]	[]	0	hSpCas9	negative selection	2884374
40681493	40681516	5	+	27260157	SF268	viability	ACACCTGGTGCTTCATCGACTGG	PTGER4	ENSG00000171522	-0.26513451653062	[]	[]	-2	hSpCas9	negative selection	2885293
40681626	40681649	5	-	27260157	SF268	viability	GCATGAACTGGCGGTGCATGCGG	PTGER4	ENSG00000171522	-0.740678638253876	[]	[]	-5	hSpCas9	negative selection	2886331
40681185	40681208	5	+	27260157	SF268	viability	CGACCTGTTGGGCACTTTGTTGG	PTGER4	ENSG00000171522	-1.32604423980934	[]	[]	-7	hSpCas9	negative selection	2886772
40681032	40681055	5	-	27260157	SF268	viability	CTGGGCTGTTCAGCCGGTCGGGG	PTGER4	ENSG00000171522	0.14004931227673	[]	[]	0	hSpCas9	negative selection	2889137
40681517	40681540	5	-	27260157	SF268	viability	GGCGTGCGCCGTCACGTTGGTGG	PTGER4	ENSG00000171522	-1.17609144020906	[]	[]	-7	hSpCas9	negative selection	2890847
40681488	40681511	5	-	27260157	SF268	viability	CGATGAAGCACCAGGTGTCTGGG	PTGER4	ENSG00000171522	0.587466245377042	[]	[]	8	hSpCas9	negative selection	2910541
40681571	40681594	5	-	27260157	SF268	viability	GACGGTGGCGAGAATGAGGAAGG	PTGER4	ENSG00000171522	1.40648547789409	[]	[]	9	hSpCas9	negative selection	2913768
40681231	40681254	5	+	27260157	SF268	viability	TACATGAAGGGCCAATGGCCCGG	PTGER4	ENSG00000171522	0.451336127355017	[]	[]	7	hSpCas9	negative selection	2916259
40681143	40681166	5	+	27260157	SF268	viability	GGAGACGACCTTCTACACGCTGG	PTGER4	ENSG00000171522	0.620065107281746	[]	[]	8	hSpCas9	negative selection	2916590
40681594	40681617	5	+	27260157	SF268	viability	CTCTGCAACGTGCTTGTGTGCGG	PTGER4	ENSG00000171522	0.0984683274979033	[]	[]	0	hSpCas9	negative selection	2916969
40681004	40681027	5	-	27260157	SF268	viability	GGAGGCGGACGAATTGACCCCGG	PTGER4	ENSG00000171522	-0.280594222089422	[]	[]	-2	hSpCas9	negative selection	2920944
40681050	40681073	5	-	27260157	SF268	viability	TCACCGCCGGGATGGTCACTGGG	PTGER4	ENSG00000171522	-0.319012903172051	[]	[]	-2	hSpCas9	negative selection	2921505
40681347	40681370	5	-	27260157	SF268	viability	AATAGGCATGGTTGATGGCCAGG	PTGER4	ENSG00000171522	-0.079604973729547	[]	[]	0	hSpCas9	negative selection	2923713
40681509	40681532	5	+	27260157	SF268	viability	CGACTGGACCACCAACGTGACGG	PTGER4	ENSG00000171522	1.41220043503524	[]	[]	9	hSpCas9	negative selection	2928128
40681377	40681400	5	-	27260157	SF268	viability	CCAATCGCTTGTCCACGTAGTGG	PTGER4	ENSG00000171522	-0.650102649055823	[]	[]	-5	hSpCas9	negative selection	2946680
40681226	40681249	5	-	27260157	SF268	viability	CCATTGGCCCTTCATGTACGTGG	PTGER4	ENSG00000171522	0.762997999165481	[]	[]	8	hSpCas9	negative selection	2948660
40681539	40681562	5	+	27260157	SF268	viability	CGCCTACTCCTACATGTACGCGG	PTGER4	ENSG00000171522	-0.253220113642119	[]	[]	-2	hSpCas9	negative selection	2949570
40681447	40681470	5	+	27260157	SF268	viability	GCGCTGCCCAACATGGGTCTCGG	PTGER4	ENSG00000171522	-0.854063715243863	[]	[]	-6	hSpCas9	negative selection	2953572
40681261	40681284	5	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	AAGGTGCTGTACTCGCACAGCGG	PTGER4	ENSG00000171522	0.09860677576255264	[4,4]	[4,3]	2	hSpCas9	positive selection	3014574
40681048	40681071	5	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CAGCCCAGTGACCATCCCGGCGG	PTGER4	ENSG00000171522	-0.22629392729242215	[3,2]	[1,2]	-3	hSpCas9	positive selection	3014575
40681366	40681389	5	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CTATTTCTACAGCCACTACGTGG	PTGER4	ENSG00000171522	-0.39317029907688283	[3,3]	[3,1]	-5	hSpCas9	positive selection	3014576
40681663	40681686	5	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GGGCACCGAGCAGCACCACGCGG	PTGER4	ENSG00000171522	-0.4020399155171795	[3,2]	[3,0]	-5	hSpCas9	positive selection	3014577
40681261	40681284	5	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	AAGGTGCTGTACTCGCACAGCGG	PTGER4	ENSG00000171522	-0.7129345426401017	[4,4]	[2,0]	-8	hSpCas9	positive selection	3082432
40681048	40681071	5	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CAGCCCAGTGACCATCCCGGCGG	PTGER4	ENSG00000171522	-0.5769821272831657	[3,3]	[2,0]	-7	hSpCas9	positive selection	3082433
40681366	40681389	5	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CTATTTCTACAGCCACTACGTGG	PTGER4	ENSG00000171522	0.01846029729030539	[3,3]	[2,2]	0	hSpCas9	positive selection	3082434
40681663	40681686	5	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GGGCACCGAGCAGCACCACGCGG	PTGER4	ENSG00000171522	-0.7207818428060383	[3,3]	[2,0]	-8	hSpCas9	positive selection	3082435
40691958	40691981		-	24336571	A375	resistance to PLX after 7 days	CCCTGCGGGACCCGCCAATGCGG	PTGER4	ENSG00000171522	0.36539013527442704	[10,13]	[14,16]	8	hSpCas9	positive selection	3138661
40681063	40681086		-	24336571	A375	resistance to PLX after 7 days	CCGAAGATGAACATCACCGCCGG	PTGER4	ENSG00000171522	0.19791035048049033	[7,8]	[8,9]	6	hSpCas9	positive selection	3138662
40681454	40681477		-	24336571	A375	resistance to PLX after 7 days	CGAGCTACCGAGACCCATGTTGG	PTGER4	ENSG00000171522	0.3915620226651909	[14,14]	[17,20]	8	hSpCas9	positive selection	3138663
40691809	40691832		-	24336571	A375	resistance to PLX after 7 days	CTGACTTCTCGCTCCAAACTTGG	PTGER4	ENSG00000171522	-0.23049855315115703	[9,9]	[8,7]	-7	hSpCas9	positive selection	3138665
40681638	40681661		-	24336571	A375	resistance to PLX after 7 days	GCGAGGTGCGGCGCATGAACTGG	PTGER4	ENSG00000171522	-0.18162771036182881	[15,18]	[14,14]	-6	hSpCas9	positive selection	3138666
40691880	40691903		-	24336571	A375	resistance to PLX after 7 days	GGATATATATCCAGGGGTCTAGG	PTGER4	ENSG00000171522	-0.03891836514782221	[2,3]	[2,3]	-1	hSpCas9	positive selection	3138667
40691958	40691981		-	24336571	A375	resistance to PLX after 14 days	CCCTGCGGGACCCGCCAATGCGG	PTGER4	ENSG00000171522	-0.25803532550873354	[17,16]	[6,6]	-3	hSpCas9	positive selection	3196454
40681063	40681086		-	24336571	A375	resistance to PLX after 14 days	CCGAAGATGAACATCACCGCCGG	PTGER4	ENSG00000171522	-0.733659662238233	[9,14]	[2,3]	-8	hSpCas9	positive selection	3196455
40681454	40681477		-	24336571	A375	resistance to PLX after 14 days	CGAGCTACCGAGACCCATGTTGG	PTGER4	ENSG00000171522	5.714888886298549	[16,30]	[791,429]	9	hSpCas9	positive selection	3196456
40691809	40691832		-	24336571	A375	resistance to PLX after 14 days	CTGACTTCTCGCTCCAAACTTGG	PTGER4	ENSG00000171522	-0.73559070051916	[10,9]	[2,1]	-8	hSpCas9	positive selection	3196458
40681638	40681661		-	24336571	A375	resistance to PLX after 14 days	GCGAGGTGCGGCGCATGAACTGG	PTGER4	ENSG00000171522	-0.1598104685507844	[19,15]	[6,6]	-2	hSpCas9	positive selection	3196459
40691880	40691903		-	24336571	A375	resistance to PLX after 14 days	GGATATATATCCAGGGGTCTAGG	PTGER4	ENSG00000171522	0.6428780275158021	[1,2]	[1,1]	6	hSpCas9	positive selection	3196460
40691958	40691981		-	24336571	A375	viability after 7 days	CCCTGCGGGACCCGCCAATGCGG	PTGER4	ENSG00000171522	0.6847683040954283	[7]	[10,13]	8	hSpCas9	negative selection	3254247
40681063	40681086		-	24336571	A375	viability after 7 days	CCGAAGATGAACATCACCGCCGG	PTGER4	ENSG00000171522	-0.28469381591610393	[10]	[7,8]	-4	hSpCas9	negative selection	3254248
40681454	40681477		-	24336571	A375	viability after 7 days	CGAGCTACCGAGACCCATGTTGG	PTGER4	ENSG00000171522	-0.07287754007705396	[16]	[14,14]	-1	hSpCas9	negative selection	3254249
40691809	40691832		-	24336571	A375	viability after 7 days	CTGACTTCTCGCTCCAAACTTGG	PTGER4	ENSG00000171522	-0.39326365992750945	[13]	[9,9]	-5	hSpCas9	negative selection	3254251
40681638	40681661		-	24336571	A375	viability after 7 days	GCGAGGTGCGGCGCATGAACTGG	PTGER4	ENSG00000171522	0.4309827208645373	[13]	[15,18]	6	hSpCas9	negative selection	3254252
40691880	40691903		-	24336571	A375	viability after 7 days	GGATATATATCCAGGGGTCTAGG	PTGER4	ENSG00000171522	-0.23266681103570752	[3]	[2,3]	-3	hSpCas9	negative selection	3254253
40691958	40691981		-	24336571	A375	viability after 14 days	CCCTGCGGGACCCGCCAATGCGG	PTGER4	ENSG00000171522	1.1680845731236922	[7]	[17,16]	9	hSpCas9	negative selection	3312040
40681063	40681086		-	24336571	A375	viability after 14 days	CCGAAGATGAACATCACCGCCGG	PTGER4	ENSG00000171522	0.2888416165608207	[10]	[9,14]	4	hSpCas9	negative selection	3312041
40681454	40681477		-	24336571	A375	viability after 14 days	CGAGCTACCGAGACCCATGTTGG	PTGER4	ENSG00000171522	0.6385085760605312	[16]	[16,30]	7	hSpCas9	negative selection	3312042
40691809	40691832		-	24336571	A375	viability after 14 days	CTGACTTCTCGCTCCAAACTTGG	PTGER4	ENSG00000171522	-0.3278412645614949	[13]	[10,9]	-4	hSpCas9	negative selection	3312044
40681638	40681661		-	24336571	A375	viability after 14 days	GCGAGGTGCGGCGCATGAACTGG	PTGER4	ENSG00000171522	0.4745651049572701	[13]	[19,15]	6	hSpCas9	negative selection	3312045
40691880	40691903		-	24336571	A375	viability after 14 days	GGATATATATCCAGGGGTCTAGG	PTGER4	ENSG00000171522	-0.5313148363780789	[3]	[1,2]	-6	hSpCas9	negative selection	3312046
40691944	40691967	5	+	27383988	293T	resistance to West Nile virus (flavivirus)	AAATGCCTCTTCTGCCGCATTGG	PTGER4	ENSG00000171522	-1.3792984090978138	[397,397]	[0,0]	-8	hSpCas9	positive selection	3388167
40681539	40681562	5	+	27383988	293T	resistance to West Nile virus (flavivirus)	CGCCTACTCCTACATGTACGCGG	PTGER4	ENSG00000171522	-1.0914019427852424	[325,325]	[0,0]	-7	hSpCas9	positive selection	3388168
40681638	40681661	5	-	27383988	293T	resistance to West Nile virus (flavivirus)	GCGAGGTGCGGCGCATGAACTGG	PTGER4	ENSG00000171522	1.399345216318263	[57,57]	[0,0]	6	hSpCas9	positive selection	3388169
40681261	40681284	5	-	26780180	HT29	viability (Avana library 4 designs)	AAGGTGCTGTACTCGCACAGCGG	PTGER4	ENSG00000171522	0.269588936297512	[]	[]	0	hSpCas9	negative selection	3452814
40681047	40681070	5	+	26780180	HT29	viability (Avana library 4 designs)	CAGCCCAGTGACCATCCCGGCGG	PTGER4	ENSG00000171522	1.74853111493948	[]	[]	6	hSpCas9	negative selection	3452815
40681365	40681388	5	+	26780180	HT29	viability (Avana library 4 designs)	CTATTTCTACAGCCACTACGTGG	PTGER4	ENSG00000171522	0.770528417799787	[]	[]	3	hSpCas9	negative selection	3452816
40681662	40681685	5	+	26780180	HT29	viability (Avana library 4 designs)	GGGCACCGAGCAGCACCACGCGG	PTGER4	ENSG00000171522	0.823004277015128	[]	[]	3	hSpCas9	negative selection	3452817
40681047	40681070	5	+	26780180	A375	viability (Avana lentiCRISPRv2)	CAGCCCAGTGACCATCCCGGCGG	PTGER4	ENSG00000171522	2.1073640304925	[]	[]	3	hSpCas9	negative selection	3549366
40681365	40681388	5	+	26780180	A375	viability (Avana lentiCRISPRv2)	CTATTTCTACAGCCACTACGTGG	PTGER4	ENSG00000171522	-0.494258668000253	[]	[]	0	hSpCas9	negative selection	3549367
40681662	40681685	5	+	26780180	A375	viability (Avana lentiCRISPRv2)	GGGCACCGAGCAGCACCACGCGG	PTGER4	ENSG00000171522	4.31249417023691	[]	[]	7	hSpCas9	negative selection	3549368
40681261	40681284	5	-	26780180	A375	viability (Avana lentiCRISPRv2)	AAGGTGCTGTACTCGCACAGCGG	PTGER4	ENSG00000171522	2.59897987357768	[]	[]	4	hSpCas9	negative selection	3549369
40681062	40681085	5	-	26780180	A375	viability (Avana lentiCRISPRv2)	CGAAGATGAACATCACCGCCGGG	PTGER4	ENSG00000171522	-0.533115585407403	[]	[]	0	hSpCas9	negative selection	3549370
40681457	40681480	5	+	26780180	A375	viability (Avana lentiCRISPRv2)	ACATGGGTCTCGGTAGCTCGCGG	PTGER4	ENSG00000171522	5.92102511357501	[]	[]	9	hSpCas9	negative selection	3549371
40681047	40681070	5	+	26780180	A375	viability (Avana lentiGuide)	CAGCCCAGTGACCATCCCGGCGG	PTGER4	ENSG00000171522	11.5333490880461	[]	[]	7	hSpCas9	negative selection	3658025
40681365	40681388	5	+	26780180	A375	viability (Avana lentiGuide)	CTATTTCTACAGCCACTACGTGG	PTGER4	ENSG00000171522	-0.687380762948989	[]	[]	-1	hSpCas9	negative selection	3658026
40681662	40681685	5	+	26780180	A375	viability (Avana lentiGuide)	GGGCACCGAGCAGCACCACGCGG	PTGER4	ENSG00000171522	-0.814359192796419	[]	[]	-1	hSpCas9	negative selection	3658027
40681261	40681284	5	-	26780180	A375	viability (Avana lentiGuide)	AAGGTGCTGTACTCGCACAGCGG	PTGER4	ENSG00000171522	-2.23138191489784	[]	[]	-4	hSpCas9	negative selection	3658028
40681062	40681085	5	-	26780180	A375	viability (Avana lentiGuide)	CGAAGATGAACATCACCGCCGGG	PTGER4	ENSG00000171522	-0.595576226993314	[]	[]	-1	hSpCas9	negative selection	3658029
40681457	40681480	5	+	26780180	A375	viability (Avana lentiGuide)	ACATGGGTCTCGGTAGCTCGCGG	PTGER4	ENSG00000171522	0.829600288371411	[]	[]	1	hSpCas9	negative selection	3658030
40681047	40681070	5	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CAGCCCAGTGACCATCCCGGCGG	PTGER4	ENSG00000171522	-0.1448582672048016	[3]	[4,1]	-2	hSpCas9	positive selection	3766632
40681365	40681388	5	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CTATTTCTACAGCCACTACGTGG	PTGER4	ENSG00000171522	-0.1508508090365173	[5]	[5,3]	-2	hSpCas9	positive selection	3766633
40681662	40681685	5	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGGCACCGAGCAGCACCACGCGG	PTGER4	ENSG00000171522	0.34092585778792533	[4]	[5,5]	8	hSpCas9	positive selection	3766634
40681261	40681284	5	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AAGGTGCTGTACTCGCACAGCGG	PTGER4	ENSG00000171522	0.17415881210537754	[6]	[6,6]	5	hSpCas9	positive selection	3766635
40681062	40681085	5	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CGAAGATGAACATCACCGCCGGG	PTGER4	ENSG00000171522	0.17242562444335452	[5]	[6,5]	5	hSpCas9	positive selection	3766636
40681457	40681480	5	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ACATGGGTCTCGGTAGCTCGCGG	PTGER4	ENSG00000171522	0.3248432041390462	[6]	[7,7]	8	hSpCas9	positive selection	3766637
40681047	40681070	5	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CAGCCCAGTGACCATCCCGGCGG	PTGER4	ENSG00000171522	-0.35289563609535923	[4]	[2,2]	-5	hSpCas9	positive selection	3875239
40681365	40681388	5	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CTATTTCTACAGCCACTACGTGG	PTGER4	ENSG00000171522	0.0010477988615482103	[5]	[5,3]	0	hSpCas9	positive selection	3875240
40681662	40681685	5	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGGCACCGAGCAGCACCACGCGG	PTGER4	ENSG00000171522	-0.6163074008965517	[5]	[2,2]	-7	hSpCas9	positive selection	3875241
40681261	40681284	5	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AAGGTGCTGTACTCGCACAGCGG	PTGER4	ENSG00000171522	0.06749316505623223	[5]	[5,4]	1	hSpCas9	positive selection	3875242
40681062	40681085	5	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CGAAGATGAACATCACCGCCGGG	PTGER4	ENSG00000171522	0.32886541744557374	[6]	[6,6]	8	hSpCas9	positive selection	3875243
40681457	40681480	5	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ACATGGGTCTCGGTAGCTCGCGG	PTGER4	ENSG00000171522	0.19396303189002606	[6]	[6,6]	5	hSpCas9	positive selection	3875244
40691944	40691967	5	+	26780180	A375	viability	AAATGCCTCTTCTGCCGCATTGG	PTGER4	ENSG00000171522	1.26899052045254	[]	[]	7	hSpCas9	negative selection	3985674
40681509	40681532	5	+	26780180	A375	viability	CGACTGGACCACCAACGTGACGG	PTGER4	ENSG00000171522	1.43683627579499	[]	[]	8	hSpCas9	negative selection	3985675
40681454	40681477	5	-	26780180	A375	viability	CGAGCTACCGAGACCCATGTTGG	PTGER4	ENSG00000171522	1.35751054103481	[]	[]	7	hSpCas9	negative selection	3985676
40681539	40681562	5	+	26780180	A375	viability	CGCCTACTCCTACATGTACGCGG	PTGER4	ENSG00000171522	1.67656156370682	[]	[]	9	hSpCas9	negative selection	3985677
40691809	40691832	5	-	26780180	A375	viability	CTGACTTCTCGCTCCAAACTTGG	PTGER4	ENSG00000171522	0.367765550228721	[]	[]	0	hSpCas9	negative selection	3985678
40681638	40681661	5	-	26780180	A375	viability	GCGAGGTGCGGCGCATGAACTGG	PTGER4	ENSG00000171522	1.29510544079502	[]	[]	7	hSpCas9	negative selection	3985679
40691944	40691967	5	+	26780180	HT29	viability (GeCKOv2 library)	AAATGCCTCTTCTGCCGCATTGG	PTGER4	ENSG00000171522	0.670920037298319	[]	[]	2	hSpCas9	negative selection	4093640
40681509	40681532	5	+	26780180	HT29	viability (GeCKOv2 library)	CGACTGGACCACCAACGTGACGG	PTGER4	ENSG00000171522	0.995160158555589	[]	[]	4	hSpCas9	negative selection	4093641
40681454	40681477	5	-	26780180	HT29	viability (GeCKOv2 library)	CGAGCTACCGAGACCCATGTTGG	PTGER4	ENSG00000171522	1.68709972177053	[]	[]	8	hSpCas9	negative selection	4093642
40681539	40681562	5	+	26780180	HT29	viability (GeCKOv2 library)	CGCCTACTCCTACATGTACGCGG	PTGER4	ENSG00000171522	0.639278842809411	[]	[]	2	hSpCas9	negative selection	4093643
40691809	40691832	5	-	26780180	HT29	viability (GeCKOv2 library)	CTGACTTCTCGCTCCAAACTTGG	PTGER4	ENSG00000171522	0.442234691382485	[]	[]	1	hSpCas9	negative selection	4093644
40681638	40681661	5	-	26780180	HT29	viability (GeCKOv2 library)	GCGAGGTGCGGCGCATGAACTGG	PTGER4	ENSG00000171522	1.57011571888444	[]	[]	8	hSpCas9	negative selection	4093645
40691958	40691981	5	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CCCTGCGGGACCCGCCAATGCGG	PTGER4	ENSG00000171522	-0.0004660125182186642	[3]	[2,2]	0	hSpCas9	positive selection	4163915
40681063	40681086	5	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CCGAAGATGAACATCACCGCCGG	PTGER4	ENSG00000171522	-0.17407042370303172	[2]	[1,1]	-4	hSpCas9	positive selection	4163916
40681454	40681477	5	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CGAGCTACCGAGACCCATGTTGG	PTGER4	ENSG00000171522	1.049824259688652	[3]	[2,9]	9	hSpCas9	positive selection	4163917
40691809	40691832	5	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CTGACTTCTCGCTCCAAACTTGG	PTGER4	ENSG00000171522	-0.2666612146949513	[3]	[1,1]	-6	hSpCas9	positive selection	4163919
40681638	40681661	5	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GCGAGGTGCGGCGCATGAACTGG	PTGER4	ENSG00000171522	-0.04922715031884595	[4]	[2,2]	-1	hSpCas9	positive selection	4163920
40691880	40691903	5	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GGATATATATCCAGGGGTCTAGG	PTGER4	ENSG00000171522	-0.516838470206651	[1]	[0,0]	-8	hSpCas9	positive selection	4163921
40691958	40691981	5	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CCCTGCGGGACCCGCCAATGCGG	PTGER4	ENSG00000171522	-0.04227336350210047	[3]	[0,4,1,0]	0	hSpCas9	positive selection	4227937
40681063	40681086	5	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CCGAAGATGAACATCACCGCCGG	PTGER4	ENSG00000171522	1.2416732739159342	[1]	[0,2,4,0]	8	hSpCas9	positive selection	4227938
40681454	40681477	5	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CGAGCTACCGAGACCCATGTTGG	PTGER4	ENSG00000171522	0.8432437613495813	[2]	[2,3,2,0]	5	hSpCas9	positive selection	4227939
40691809	40691832	5	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CTGACTTCTCGCTCCAAACTTGG	PTGER4	ENSG00000171522	0.455878808155267	[3]	[3,3,1,0]	3	hSpCas9	positive selection	4227941
40681638	40681661	5	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GCGAGGTGCGGCGCATGAACTGG	PTGER4	ENSG00000171522	0.6233192569909028	[4]	[0,2,1,3]	4	hSpCas9	positive selection	4227942
40691880	40691903	5	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GGATATATATCCAGGGGTCTAGG	PTGER4	ENSG00000171522	0.34734491482270163	[1]	[0,2,0,0]	2	hSpCas9	positive selection	4227943
40681454	40681477	5	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CGAGCTACCGAGACCCATGTTGG	PTGER4	ENSG00000171522	-0.10322318502323183	[3]	[3,1]	-2	hSpCas9	positive selection	4292954
40681509	40681532	5	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CGACTGGACCACCAACGTGACGG	PTGER4	ENSG00000171522	0.3177649270039755	[3]	[2,3]	6	hSpCas9	positive selection	4292955
40691809	40691832	5	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CTGACTTCTCGCTCCAAACTTGG	PTGER4	ENSG00000171522	0.30674264055847156	[3]	[4,3]	6	hSpCas9	positive selection	4292956
40691944	40691967	5	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AAATGCCTCTTCTGCCGCATTGG	PTGER4	ENSG00000171522	-0.14899019199748514	[3]	[4,1]	-3	hSpCas9	positive selection	4357213
40681539	40681562	5	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CGCCTACTCCTACATGTACGCGG	PTGER4	ENSG00000171522	0.13720592542777243	[3]	[3,2]	2	hSpCas9	positive selection	4357214
40681638	40681661	5	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GCGAGGTGCGGCGCATGAACTGG	PTGER4	ENSG00000171522	-0.11293465478745585	[1]	[1,0]	-2	hSpCas9	positive selection	4357215
40681144	40681166	5	+	27760321	OCIAML3	viability	GAGACGACCTTCTACACGCTGG	PTGER4	ENSG00000171522	-0.4153444750170524	[1058,976]	[530,682]	-4	hSpCas9	negative selection	4431723
40681377	40681399	5	-	27760321	OCIAML3	viability	CAATCGCTTGTCCACGTAGTGG	PTGER4	ENSG00000171522	-0.15711872798693677	[619,521]	[444,338]	-2	hSpCas9	negative selection	4431724
40681442	40681464	5	+	27760321	OCIAML3	viability	TTTGCGCGCTGCCCAACATGGG	PTGER4	ENSG00000171522	0.2699008554339303	[677,602]	[530,696]	3	hSpCas9	negative selection	4431725
40681510	40681532	5	+	27760321	OCIAML3	viability	GACTGGACCACCAACGTGACGG	PTGER4	ENSG00000171522	0.09406413622465995	[491,393]	[236,537]	1	hSpCas9	negative selection	4431726
40681541	40681563	5	+	27760321	OCIAML3	viability	CCTACTCCTACATGTACGCGGG	PTGER4	ENSG00000171522	-0.7292344931069802	[1191,967]	[439,593]	-6	hSpCas9	negative selection	4431727
40681144	40681166	5	+	27760321	OCIAML2	viability	GAGACGACCTTCTACACGCTGG	PTGER4	ENSG00000171522	-0.15897790332600192	[1058,976]	[652,848]	-2	hSpCas9	negative selection	4515186
40681377	40681399	5	-	27760321	OCIAML2	viability	CAATCGCTTGTCCACGTAGTGG	PTGER4	ENSG00000171522	-0.27809326411654184	[619,521]	[347,420]	-3	hSpCas9	negative selection	4515187
40681442	40681464	5	+	27760321	OCIAML2	viability	TTTGCGCGCTGCCCAACATGGG	PTGER4	ENSG00000171522	-0.010834652406983336	[677,602]	[484,550]	0	hSpCas9	negative selection	4515188
40681510	40681532	5	+	27760321	OCIAML2	viability	GACTGGACCACCAACGTGACGG	PTGER4	ENSG00000171522	0.11160535132725641	[491,393]	[308,484]	1	hSpCas9	negative selection	4515189
40681541	40681563	5	+	27760321	OCIAML2	viability	CCTACTCCTACATGTACGCGGG	PTGER4	ENSG00000171522	-0.23868942409975902	[1191,967]	[588,930]	-3	hSpCas9	negative selection	4515190
40681144	40681166	5	+	27760321	MV411	viability	GAGACGACCTTCTACACGCTGG	PTGER4	ENSG00000171522	0.4360775696541701	[1058,976]	[479,1552]	3	hSpCas9	negative selection	4598649
40681377	40681399	5	-	27760321	MV411	viability	CAATCGCTTGTCCACGTAGTGG	PTGER4	ENSG00000171522	-0.12146870547090599	[619,521]	[434,209]	-1	hSpCas9	negative selection	4598650
40681442	40681464	5	+	27760321	MV411	viability	TTTGCGCGCTGCCCAACATGGG	PTGER4	ENSG00000171522	-0.45446986434982567	[677,602]	[287,337]	-3	hSpCas9	negative selection	4598651
40681510	40681532	5	+	27760321	MV411	viability	GACTGGACCACCAACGTGACGG	PTGER4	ENSG00000171522	0.3547603043181078	[491,393]	[208,615]	2	hSpCas9	negative selection	4598652
40681541	40681563	5	+	27760321	MV411	viability	CCTACTCCTACATGTACGCGGG	PTGER4	ENSG00000171522	0.7773046133532961	[1191,967]	[1354,1004]	6	hSpCas9	negative selection	4598653
40681144	40681166	5	+	27760321	HL60	viability	GAGACGACCTTCTACACGCTGG	PTGER4	ENSG00000171522	0.2439795643892022	[1058,976]	[1192,763]	3	hSpCas9	negative selection	4682112
40681377	40681399	5	-	27760321	HL60	viability	CAATCGCTTGTCCACGTAGTGG	PTGER4	ENSG00000171522	0.16717795399297664	[619,521]	[563,476]	2	hSpCas9	negative selection	4682113
40681442	40681464	5	+	27760321	HL60	viability	TTTGCGCGCTGCCCAACATGGG	PTGER4	ENSG00000171522	0.29093494002199016	[677,602]	[709,563]	3	hSpCas9	negative selection	4682114
40681510	40681532	5	+	27760321	HL60	viability	GACTGGACCACCAACGTGACGG	PTGER4	ENSG00000171522	0.3654761494564373	[491,393]	[413,515]	4	hSpCas9	negative selection	4682115
40681541	40681563	5	+	27760321	HL60	viability	CCTACTCCTACATGTACGCGGG	PTGER4	ENSG00000171522	-0.23823649075347508	[1191,967]	[661,830]	-3	hSpCas9	negative selection	4682116
40681144	40681166	5	+	27760321	HT1080	viability	GAGACGACCTTCTACACGCTGG	PTGER4	ENSG00000171522	0.7051022523334249	[976,762]	[586,540]	4	hSpCas9	negative selection	4765575
40681377	40681399	5	-	27760321	HT1080	viability	CAATCGCTTGTCCACGTAGTGG	PTGER4	ENSG00000171522	-0.4348918398609866	[521,407]	[137,135]	-2	hSpCas9	negative selection	4765576
40681442	40681464	5	+	27760321	HT1080	viability	TTTGCGCGCTGCCCAACATGGG	PTGER4	ENSG00000171522	0.6581198355317793	[602,470]	[444,219]	3	hSpCas9	negative selection	4765577
40681510	40681532	5	+	27760321	HT1080	viability	GACTGGACCACCAACGTGACGG	PTGER4	ENSG00000171522	1.2486108443111883	[393,307]	[274,394]	6	hSpCas9	negative selection	4765578
40681541	40681563	5	+	27760321	HT1080	viability	CCTACTCCTACATGTACGCGGG	PTGER4	ENSG00000171522	0.39328536906076095	[967,755]	[282,634]	2	hSpCas9	negative selection	4765579
40681144	40681166	5	+	27760321	HT29	viability after 7 days	GAGACGACCTTCTACACGCTGG	PTGER4	ENSG00000171522	-0.5750986694163699	[976,762]	[866,902,505]	-7	hSpCas9	negative selection	4849038
40681377	40681399	5	-	27760321	HT29	viability after 7 days	CAATCGCTTGTCCACGTAGTGG	PTGER4	ENSG00000171522	0.1973643185552933	[521,407]	[476,800,745]	3	hSpCas9	negative selection	4849039
40681442	40681464	5	+	27760321	HT29	viability after 7 days	TTTGCGCGCTGCCCAACATGGG	PTGER4	ENSG00000171522	-0.03901166135929124	[602,470]	[754,695,578]	0	hSpCas9	negative selection	4849040
40681510	40681532	5	+	27760321	HT29	viability after 7 days	GACTGGACCACCAACGTGACGG	PTGER4	ENSG00000171522	0.7416054269289823	[393,307]	[598,993,650]	9	hSpCas9	negative selection	4849041
40681541	40681563	5	+	27760321	HT29	viability after 7 days	CCTACTCCTACATGTACGCGGG	PTGER4	ENSG00000171522	0.145615720831485	[967,755]	[1332,1399,966]	2	hSpCas9	negative selection	4849042
40681144	40681166	5	+	27760321	HT29	viability after 25 days	GAGACGACCTTCTACACGCTGG	PTGER4	ENSG00000171522	-0.2693978066492444	[976,762]	[595,859,1055]	-3	hSpCas9	negative selection	4932501
40681377	40681399	5	-	27760321	HT29	viability after 25 days	CAATCGCTTGTCCACGTAGTGG	PTGER4	ENSG00000171522	0.5117124178622114	[521,407]	[793,689,788]	5	hSpCas9	negative selection	4932502
40681442	40681464	5	+	27760321	HT29	viability after 25 days	TTTGCGCGCTGCCCAACATGGG	PTGER4	ENSG00000171522	-0.053487016178786706	[602,470]	[538,676,556]	0	hSpCas9	negative selection	4932503
40681510	40681532	5	+	27760321	HT29	viability after 25 days	GACTGGACCACCAACGTGACGG	PTGER4	ENSG00000171522	0.9698622758916426	[393,307]	[901,813,614]	9	hSpCas9	negative selection	4932504
40681541	40681563	5	+	27760321	HT29	viability after 25 days	CCTACTCCTACATGTACGCGGG	PTGER4	ENSG00000171522	0.11863302320067648	[967,755]	[848,983,1424]	1	hSpCas9	negative selection	4932505
40681144	40681166	5	+	27760321	HT29	viability after 22 days	GAGACGACCTTCTACACGCTGG	PTGER4	ENSG00000171522	-0.31379897325917594	[976,762]	[810,648,968]	-3	hSpCas9	negative selection	5015964
40681377	40681399	5	-	27760321	HT29	viability after 22 days	CAATCGCTTGTCCACGTAGTGG	PTGER4	ENSG00000171522	0.40305541266302797	[521,407]	[710,880,538]	4	hSpCas9	negative selection	5015965
40681442	40681464	5	+	27760321	HT29	viability after 22 days	TTTGCGCGCTGCCCAACATGGG	PTGER4	ENSG00000171522	-0.40932596439936375	[602,470]	[386,399,618]	-4	hSpCas9	negative selection	5015966
40681510	40681532	5	+	27760321	HT29	viability after 22 days	GACTGGACCACCAACGTGACGG	PTGER4	ENSG00000171522	1.0426866068524117	[393,307]	[1233,553,707]	9	hSpCas9	negative selection	5015967
40681541	40681563	5	+	27760321	HT29	viability after 22 days	CCTACTCCTACATGTACGCGGG	PTGER4	ENSG00000171522	0.10176787548516542	[967,755]	[1207,862,1133]	1	hSpCas9	negative selection	5015968
40681144	40681166	5	+	27760321	HT29	viability after 19 days	GAGACGACCTTCTACACGCTGG	PTGER4	ENSG00000171522	0.0945276684916323	[976,762]	[1165,824,1200]	0	hSpCas9	negative selection	5099427
40681377	40681399	5	-	27760321	HT29	viability after 19 days	CAATCGCTTGTCCACGTAGTGG	PTGER4	ENSG00000171522	0.6514125066986558	[521,407]	[868,854,786]	6	hSpCas9	negative selection	5099428
40681442	40681464	5	+	27760321	HT29	viability after 19 days	TTTGCGCGCTGCCCAACATGGG	PTGER4	ENSG00000171522	-0.47713504985241845	[602,470]	[559,231,539]	-4	hSpCas9	negative selection	5099429
40681510	40681532	5	+	27760321	HT29	viability after 19 days	GACTGGACCACCAACGTGACGG	PTGER4	ENSG00000171522	1.0609738241854174	[393,307]	[709,471,1298]	9	hSpCas9	negative selection	5099430
40681541	40681563	5	+	27760321	HT29	viability after 19 days	CCTACTCCTACATGTACGCGGG	PTGER4	ENSG00000171522	-0.47245718154541894	[967,755]	[854,678,615]	-4	hSpCas9	negative selection	5099431
40681144	40681166	5	+	27760321	HT29	viability after 16 days	GAGACGACCTTCTACACGCTGG	PTGER4	ENSG00000171522	-0.5961603872726079	[976,762]	[489,800,621]	-5	hSpCas9	negative selection	5182890
40681377	40681399	5	-	27760321	HT29	viability after 16 days	CAATCGCTTGTCCACGTAGTGG	PTGER4	ENSG00000171522	0.06527983053604003	[521,407]	[509,497,622]	0	hSpCas9	negative selection	5182891
40681442	40681464	5	+	27760321	HT29	viability after 16 days	TTTGCGCGCTGCCCAACATGGG	PTGER4	ENSG00000171522	-0.20359446584022944	[602,470]	[587,537,444]	-2	hSpCas9	negative selection	5182892
40681510	40681532	5	+	27760321	HT29	viability after 16 days	GACTGGACCACCAACGTGACGG	PTGER4	ENSG00000171522	1.030979950732207	[393,307]	[929,859,627]	9	hSpCas9	negative selection	5182893
40681541	40681563	5	+	27760321	HT29	viability after 16 days	CCTACTCCTACATGTACGCGGG	PTGER4	ENSG00000171522	-0.03672060975200542	[967,755]	[993,846,986]	0	hSpCas9	negative selection	5182894
40681144	40681166	5	+	27760321	HT29	viability after 13 days	GAGACGACCTTCTACACGCTGG	PTGER4	ENSG00000171522	-0.547750672884351	[976,762]	[839,660,576]	-6	hSpCas9	negative selection	5266353
40681377	40681399	5	-	27760321	HT29	viability after 13 days	CAATCGCTTGTCCACGTAGTGG	PTGER4	ENSG00000171522	0.18109016213537338	[521,407]	[502,769,564]	2	hSpCas9	negative selection	5266354
40681442	40681464	5	+	27760321	HT29	viability after 13 days	TTTGCGCGCTGCCCAACATGGG	PTGER4	ENSG00000171522	-0.28725052046373867	[602,470]	[469,557,503]	-4	hSpCas9	negative selection	5266355
40681510	40681532	5	+	27760321	HT29	viability after 13 days	GACTGGACCACCAACGTGACGG	PTGER4	ENSG00000171522	0.6902572502779136	[393,307]	[927,409,633]	8	hSpCas9	negative selection	5266356
40681541	40681563	5	+	27760321	HT29	viability after 13 days	CCTACTCCTACATGTACGCGGG	PTGER4	ENSG00000171522	-0.299112079172587	[967,755]	[799,820,816]	-4	hSpCas9	negative selection	5266357
40681144	40681166	5	+	27760321	HT29	viability after 10 days	GAGACGACCTTCTACACGCTGG	PTGER4	ENSG00000171522	-0.3676064014553915	[976,762]	[723,980,824]	-5	hSpCas9	negative selection	5349816
40681377	40681399	5	-	27760321	HT29	viability after 10 days	CAATCGCTTGTCCACGTAGTGG	PTGER4	ENSG00000171522	0.13731435356937677	[521,407]	[434,634,840]	1	hSpCas9	negative selection	5349817
40681442	40681464	5	+	27760321	HT29	viability after 10 days	TTTGCGCGCTGCCCAACATGGG	PTGER4	ENSG00000171522	-0.1137210926806847	[602,470]	[470,586,795]	-1	hSpCas9	negative selection	5349818
40681510	40681532	5	+	27760321	HT29	viability after 10 days	GACTGGACCACCAACGTGACGG	PTGER4	ENSG00000171522	0.7282455462910783	[393,307]	[759,828,594]	8	hSpCas9	negative selection	5349819
40681541	40681563	5	+	27760321	HT29	viability after 10 days	CCTACTCCTACATGTACGCGGG	PTGER4	ENSG00000171522	0.09695456027315719	[967,755]	[1257,1059,1132]	1	hSpCas9	negative selection	5349820
40681144	40681166	5	+	27760321	MOLM13	viability	GAGACGACCTTCTACACGCTGG	PTGER4	ENSG00000171522	-0.1457788439259471	[1058,976]	[792,285]	-1	hSpCas9	negative selection	5433279
40681377	40681399	5	-	27760321	MOLM13	viability	CAATCGCTTGTCCACGTAGTGG	PTGER4	ENSG00000171522	0.02742209744448354	[619,521]	[318,333]	0	hSpCas9	negative selection	5433280
40681442	40681464	5	+	27760321	MOLM13	viability	TTTGCGCGCTGCCCAACATGGG	PTGER4	ENSG00000171522	-0.2714400052042235	[677,602]	[319,280]	-2	hSpCas9	negative selection	5433281
40681510	40681532	5	+	27760321	MOLM13	viability	GACTGGACCACCAACGTGACGG	PTGER4	ENSG00000171522	0.5509198242357566	[491,393]	[423,312]	4	hSpCas9	negative selection	5433282
40681541	40681563	5	+	27760321	MOLM13	viability	CCTACTCCTACATGTACGCGGG	PTGER4	ENSG00000171522	-1.2068027264544907	[1191,967]	[267,257]	-6	hSpCas9	negative selection	5433283
40680437	40680460	5	-	27661255	K562	viability	GGCAGCCTCACGAGCCCCCAGGG	PTGER4	ENSG00000171522	-0.3664455255446819	[1119,1045]	[774,583]	-7	dCas9-KRAB	negative selection	5505098
40680982	40681005	5	-	27661255	K562	viability	GGAGTGGACATGATAGTGGCTGG	PTGER4	ENSG00000171522	0.2594030440501609	[368,428]	[461,310]	8	dCas9-KRAB	negative selection	5505099
40680998	40681021	5	-	27661255	K562	viability	GGACGAATTGACCCCGGGAGTGG	PTGER4	ENSG00000171522	-0.11903088618286306	[1366,1405]	[1244,826]	-4	dCas9-KRAB	negative selection	5505100
40681003	40681026	5	-	27661255	K562	viability	GAGGCGGACGAATTGACCCCGGG	PTGER4	ENSG00000171522	0.17189778587397742	[1093,1291]	[1254,912]	6	dCas9-KRAB	negative selection	5505101
40681454	40681477	5	-	27260156	BXPC3	viability	CGAGCTACCGAGACCCATGTTGG	PTGER4	ENSG00000171522	-0.598677588249497	[636]	[382,498,434,441]	-8	hSpCas9	negative selection	5565414
40681509	40681532	5	+	27260156	BXPC3	viability	CGACTGGACCACCAACGTGACGG	PTGER4	ENSG00000171522	-0.22592842343500547	[581]	[445,521,540,584]	-5	hSpCas9	negative selection	5565415
40691809	40691832	5	-	27260156	BXPC3	viability	CTGACTTCTCGCTCCAAACTTGG	PTGER4	ENSG00000171522	-0.09101087570106636	[836]	[784,822,741,948]	-2	hSpCas9	negative selection	5565416
40691944	40691967	5	+	27260156	BXPC3	viability	AAATGCCTCTTCTGCCGCATTGG	PTGER4	ENSG00000171522	-0.06018197926985436	[791]	[644,885,745,919]	-1	hSpCas9	negative selection	5629673
40681539	40681562	5	+	27260156	BXPC3	viability	CGCCTACTCCTACATGTACGCGG	PTGER4	ENSG00000171522	-0.28007453258432335	[880]	[654,686,807,914]	-6	hSpCas9	negative selection	5629674
40681638	40681661	5	-	27260156	BXPC3	viability	GCGAGGTGCGGCGCATGAACTGG	PTGER4	ENSG00000171522	-0.5958046733316125	[173]	[75,151,142,111]	-8	hSpCas9	negative selection	5629675
40681454	40681477	5	-	27260156	A673	viability	CGAGCTACCGAGACCCATGTTGG	PTGER4	ENSG00000171522	-0.36326913052984466	[636]	[613,483,637,648]	-7	hSpCas9	negative selection	5686665
40681509	40681532	5	+	27260156	A673	viability	CGACTGGACCACCAACGTGACGG	PTGER4	ENSG00000171522	0.1925310515012491	[581]	[883,643,717,970]	4	hSpCas9	negative selection	5686666
40691809	40691832	5	-	27260156	A673	viability	CTGACTTCTCGCTCCAAACTTGG	PTGER4	ENSG00000171522	0.13906395184221698	[836]	[1123,1065,1151,1083]	3	hSpCas9	negative selection	5686667
40691944	40691967	5	+	27260156	A673	viability	AAATGCCTCTTCTGCCGCATTGG	PTGER4	ENSG00000171522	0.09579162800162255	[791]	[1204,972,878,1030]	2	hSpCas9	negative selection	5750924
40681539	40681562	5	+	27260156	A673	viability	CGCCTACTCCTACATGTACGCGG	PTGER4	ENSG00000171522	-0.25132539890434447	[880]	[971,873,808,909]	-6	hSpCas9	negative selection	5750925
40681638	40681661	5	-	27260156	A673	viability	GCGAGGTGCGGCGCATGAACTGG	PTGER4	ENSG00000171522	-0.3675865646958265	[173]	[142,132,142,230]	-7	hSpCas9	negative selection	5750926
40681454	40681477	5	-	27260156	A375	viability	CGAGCTACCGAGACCCATGTTGG	PTGER4	ENSG00000171522	-0.5238274185411463	[636]	[442,825,413,436]	-6	hSpCas9	negative selection	5807916
40681509	40681532	5	+	27260156	A375	viability	CGACTGGACCACCAACGTGACGG	PTGER4	ENSG00000171522	-0.288451043073101	[581]	[536,674,485,543]	-4	hSpCas9	negative selection	5807917
40691809	40691832	5	-	27260156	A375	viability	CTGACTTCTCGCTCCAAACTTGG	PTGER4	ENSG00000171522	0.11985814531324057	[836]	[1307,1025,1096,837]	1	hSpCas9	negative selection	5807918
40691944	40691967	5	+	27260156	A375	viability	AAATGCCTCTTCTGCCGCATTGG	PTGER4	ENSG00000171522	-0.23599720558127546	[791]	[810,1043,553,767]	-3	hSpCas9	negative selection	5872175
40681539	40681562	5	+	27260156	A375	viability	CGCCTACTCCTACATGTACGCGG	PTGER4	ENSG00000171522	-0.22360700684048385	[880]	[1114,1103,774,594]	-3	hSpCas9	negative selection	5872176
40681638	40681661	5	-	27260156	A375	viability	GCGAGGTGCGGCGCATGAACTGG	PTGER4	ENSG00000171522	0.15325933221148524	[173]	[217,256,174,253]	2	hSpCas9	negative selection	5872177
40681454	40681477	5	-	27260156	COLO741	viability	CGAGCTACCGAGACCCATGTTGG	PTGER4	ENSG00000171522	-0.14845867600404067	[636]	[760,770,675]	-3	hSpCas9	negative selection	5929167
40681509	40681532	5	+	27260156	COLO741	viability	CGACTGGACCACCAACGTGACGG	PTGER4	ENSG00000171522	0.059450832294578426	[581]	[782,881,666]	1	hSpCas9	negative selection	5929168
40691809	40691832	5	-	27260156	COLO741	viability	CTGACTTCTCGCTCCAAACTTGG	PTGER4	ENSG00000171522	0.42456754060283886	[836]	[1556,1585,1188]	8	hSpCas9	negative selection	5929169
40691944	40691967	5	+	27260156	COLO741	viability	AAATGCCTCTTCTGCCGCATTGG	PTGER4	ENSG00000171522	-0.03715773773825959	[791]	[1110,1095,775]	-1	hSpCas9	negative selection	5993426
40681539	40681562	5	+	27260156	COLO741	viability	CGCCTACTCCTACATGTACGCGG	PTGER4	ENSG00000171522	-0.14844152756189732	[880]	[1221,996,854]	-3	hSpCas9	negative selection	5993427
40681638	40681661	5	-	27260156	COLO741	viability	GCGAGGTGCGGCGCATGAACTGG	PTGER4	ENSG00000171522	-0.13803135510455067	[173]	[182,203,215]	-3	hSpCas9	negative selection	5993428
40681454	40681477	5	-	27260156	CAL120	viability	CGAGCTACCGAGACCCATGTTGG	PTGER4	ENSG00000171522	-0.42838633971540074	[636]	[467,655,623]	-6	hSpCas9	negative selection	6050418
40681509	40681532	5	+	27260156	CAL120	viability	CGACTGGACCACCAACGTGACGG	PTGER4	ENSG00000171522	0.32788308489925905	[581]	[899,1230,599]	5	hSpCas9	negative selection	6050419
40691809	40691832	5	-	27260156	CAL120	viability	CTGACTTCTCGCTCCAAACTTGG	PTGER4	ENSG00000171522	0.754315584957902	[836]	[2091,1613,1616]	9	hSpCas9	negative selection	6050420
40691944	40691967	5	+	27260156	CAL120	viability	AAATGCCTCTTCTGCCGCATTGG	PTGER4	ENSG00000171522	-0.09343275903022752	[791]	[1001,876,903]	-1	hSpCas9	negative selection	6114677
40681539	40681562	5	+	27260156	CAL120	viability	CGCCTACTCCTACATGTACGCGG	PTGER4	ENSG00000171522	-0.05499474294110529	[880]	[1512,1038,688]	-1	hSpCas9	negative selection	6114678
40681638	40681661	5	-	27260156	CAL120	viability	GCGAGGTGCGGCGCATGAACTGG	PTGER4	ENSG00000171522	1.2187708012069316	[173]	[1317,251,71]	9	hSpCas9	negative selection	6114679
40681454	40681477	5	-	27260156	CADOES1	viability	CGAGCTACCGAGACCCATGTTGG	PTGER4	ENSG00000171522	-0.45803957801620343	[636]	[333,436,430,526]	-7	hSpCas9	negative selection	6171669
40681509	40681532	5	+	27260156	CADOES1	viability	CGACTGGACCACCAACGTGACGG	PTGER4	ENSG00000171522	0.0835594328738668	[581]	[739,423,620,505]	1	hSpCas9	negative selection	6171670
40691809	40691832	5	-	27260156	CADOES1	viability	CTGACTTCTCGCTCCAAACTTGG	PTGER4	ENSG00000171522	0.09146338972445667	[836]	[740,806,934,834]	1	hSpCas9	negative selection	6171671
40691944	40691967	5	+	27260156	CADOES1	viability	AAATGCCTCTTCTGCCGCATTGG	PTGER4	ENSG00000171522	-0.0935531557819782	[791]	[772,859,555,567]	-1	hSpCas9	negative selection	6235928
40681539	40681562	5	+	27260156	CADOES1	viability	CGCCTACTCCTACATGTACGCGG	PTGER4	ENSG00000171522	-0.024243915778830005	[880]	[934,657,702,930]	0	hSpCas9	negative selection	6235929
40681638	40681661	5	-	27260156	CADOES1	viability	GCGAGGTGCGGCGCATGAACTGG	PTGER4	ENSG00000171522	-0.06329305461304258	[173]	[181,78,210,146]	-1	hSpCas9	negative selection	6235930
40681454	40681477	5	-	27260156	EWS502	viability	CGAGCTACCGAGACCCATGTTGG	PTGER4	ENSG00000171522	-0.5966467295269913	[636]	[322,519,485,467]	-7	hSpCas9	negative selection	6292920
40681509	40681532	5	+	27260156	EWS502	viability	CGACTGGACCACCAACGTGACGG	PTGER4	ENSG00000171522	0.0773975384200799	[581]	[714,538,778,557]	1	hSpCas9	negative selection	6292921
40691809	40691832	5	-	27260156	EWS502	viability	CTGACTTCTCGCTCCAAACTTGG	PTGER4	ENSG00000171522	0.23435487254492315	[836]	[1002,950,924,1314]	4	hSpCas9	negative selection	6292922
40691944	40691967	5	+	27260156	EWS502	viability	AAATGCCTCTTCTGCCGCATTGG	PTGER4	ENSG00000171522	0.11430515415248821	[791]	[816,884,876,1072]	2	hSpCas9	negative selection	6357179
40681539	40681562	5	+	27260156	EWS502	viability	CGCCTACTCCTACATGTACGCGG	PTGER4	ENSG00000171522	-0.2723304813556141	[880]	[637,975,733,744]	-5	hSpCas9	negative selection	6357180
40681638	40681661	5	-	27260156	EWS502	viability	GCGAGGTGCGGCGCATGAACTGG	PTGER4	ENSG00000171522	-0.18556318681187145	[173]	[158,96,194,202]	-3	hSpCas9	negative selection	6357181
40681454	40681477	5	-	27260156	EW8	viability	CGAGCTACCGAGACCCATGTTGG	PTGER4	ENSG00000171522	-0.3398683080295705	[636]	[444,362,498,311]	-6	hSpCas9	negative selection	6414171
40681509	40681532	5	+	27260156	EW8	viability	CGACTGGACCACCAACGTGACGG	PTGER4	ENSG00000171522	-0.05166062119878345	[581]	[498,550,368,419]	-1	hSpCas9	negative selection	6414172
40691809	40691832	5	-	27260156	EW8	viability	CTGACTTCTCGCTCCAAACTTGG	PTGER4	ENSG00000171522	-0.022592052315008937	[836]	[710,688,638,639]	0	hSpCas9	negative selection	6414173
40691944	40691967	5	+	27260156	EW8	viability	AAATGCCTCTTCTGCCGCATTGG	PTGER4	ENSG00000171522	0.04019966881113457	[791]	[821,728,532,593]	0	hSpCas9	negative selection	6478430
40681539	40681562	5	+	27260156	EW8	viability	CGCCTACTCCTACATGTACGCGG	PTGER4	ENSG00000171522	-0.15902753590108165	[880]	[1009,763,403,459]	-3	hSpCas9	negative selection	6478431
40681638	40681661	5	-	27260156	EW8	viability	GCGAGGTGCGGCGCATGAACTGG	PTGER4	ENSG00000171522	-0.19311445965827523	[173]	[137,49,165,132]	-4	hSpCas9	negative selection	6478432
40681454	40681477	5	-	27260156	CORL105	viability	CGAGCTACCGAGACCCATGTTGG	PTGER4	ENSG00000171522	-0.09096825507141953	[636]	[491,739,807,768]	-2	hSpCas9	negative selection	6535422
40681509	40681532	5	+	27260156	CORL105	viability	CGACTGGACCACCAACGTGACGG	PTGER4	ENSG00000171522	0.13120686530762354	[581]	[624,757,847,764]	2	hSpCas9	negative selection	6535423
40691809	40691832	5	-	27260156	CORL105	viability	CTGACTTCTCGCTCCAAACTTGG	PTGER4	ENSG00000171522	0.1998622315014167	[836]	[1323,1002,1231,968]	4	hSpCas9	negative selection	6535424
40691944	40691967	5	+	27260156	CORL105	viability	AAATGCCTCTTCTGCCGCATTGG	PTGER4	ENSG00000171522	-0.11533935265506523	[791]	[796,653,1228,803]	-2	hSpCas9	negative selection	6599681
40681539	40681562	5	+	27260156	CORL105	viability	CGCCTACTCCTACATGTACGCGG	PTGER4	ENSG00000171522	-0.06693763753241255	[880]	[876,837,1351,927]	-1	hSpCas9	negative selection	6599682
40681638	40681661	5	-	27260156	CORL105	viability	GCGAGGTGCGGCGCATGAACTGG	PTGER4	ENSG00000171522	-0.15719092240327082	[173]	[137,238,119,220]	-3	hSpCas9	negative selection	6599683
40681454	40681477	5	-	27260156	HS294T	viability	CGAGCTACCGAGACCCATGTTGG	PTGER4	ENSG00000171522	-0.33424553037897337	[636]	[216,164,200,196]	-5	hSpCas9	negative selection	6656673
40681509	40681532	5	+	27260156	HS294T	viability	CGACTGGACCACCAACGTGACGG	PTGER4	ENSG00000171522	0.1304002756861724	[581]	[195,341,196,251]	1	hSpCas9	negative selection	6656674
40691809	40691832	5	-	27260156	HS294T	viability	CTGACTTCTCGCTCCAAACTTGG	PTGER4	ENSG00000171522	0.16374393804864606	[836]	[282,271,430,495]	2	hSpCas9	negative selection	6656675
40691944	40691967	5	+	27260156	HS294T	viability	AAATGCCTCTTCTGCCGCATTGG	PTGER4	ENSG00000171522	-0.08522965918202796	[791]	[258,325,217,364]	-1	hSpCas9	negative selection	6720932
40681539	40681562	5	+	27260156	HS294T	viability	CGCCTACTCCTACATGTACGCGG	PTGER4	ENSG00000171522	0.406875600368368	[880]	[296,430,299,860]	5	hSpCas9	negative selection	6720933
40681638	40681661	5	-	27260156	HS294T	viability	GCGAGGTGCGGCGCATGAACTGG	PTGER4	ENSG00000171522	-0.12121997828510511	[173]	[62,50,83,46]	-2	hSpCas9	negative selection	6720934
40681454	40681477	5	-	27260156	HCC44	viability	CGAGCTACCGAGACCCATGTTGG	PTGER4	ENSG00000171522	-0.13353121147973873	[636]	[644,580,955,505]	-2	hSpCas9	negative selection	6777924
40681509	40681532	5	+	27260156	HCC44	viability	CGACTGGACCACCAACGTGACGG	PTGER4	ENSG00000171522	-0.031037612937688863	[581]	[633,504,627,814]	0	hSpCas9	negative selection	6777925
40691809	40691832	5	-	27260156	HCC44	viability	CTGACTTCTCGCTCCAAACTTGG	PTGER4	ENSG00000171522	0.4213047788953035	[836]	[1304,1070,1493,1260]	7	hSpCas9	negative selection	6777926
40691944	40691967	5	+	27260156	HCC44	viability	AAATGCCTCTTCTGCCGCATTGG	PTGER4	ENSG00000171522	0.46382511454709574	[791]	[1204,1146,1117,1443]	7	hSpCas9	negative selection	6842183
40681539	40681562	5	+	27260156	HCC44	viability	CGCCTACTCCTACATGTACGCGG	PTGER4	ENSG00000171522	0.08236221167213154	[880]	[1095,909,1086,1144]	1	hSpCas9	negative selection	6842184
40681638	40681661	5	-	27260156	HCC44	viability	GCGAGGTGCGGCGCATGAACTGG	PTGER4	ENSG00000171522	-0.12985707272761715	[173]	[164,99,256,217]	-2	hSpCas9	negative selection	6842185
40681454	40681477	5	-	27260156	G402	viability	CGAGCTACCGAGACCCATGTTGG	PTGER4	ENSG00000171522	-0.663645234372748	[636]	[437,669,563,300]	-7	hSpCas9	negative selection	6899175
40681509	40681532	5	+	27260156	G402	viability	CGACTGGACCACCAACGTGACGG	PTGER4	ENSG00000171522	-0.297188533328453	[581]	[782,719,320,525]	-4	hSpCas9	negative selection	6899176
40691809	40691832	5	-	27260156	G402	viability	CTGACTTCTCGCTCCAAACTTGG	PTGER4	ENSG00000171522	-0.0630881226469252	[836]	[1152,1378,608,821]	-1	hSpCas9	negative selection	6899177
40691944	40691967	5	+	27260156	G402	viability	AAATGCCTCTTCTGCCGCATTGG	PTGER4	ENSG00000171522	0.1732741656364266	[791]	[892,1063,1494,882]	2	hSpCas9	negative selection	6963434
40681539	40681562	5	+	27260156	G402	viability	CGCCTACTCCTACATGTACGCGG	PTGER4	ENSG00000171522	0.09865276716952565	[880]	[1344,1205,1669,444]	1	hSpCas9	negative selection	6963435
40681638	40681661	5	-	27260156	G402	viability	GCGAGGTGCGGCGCATGAACTGG	PTGER4	ENSG00000171522	-0.20337605188275898	[173]	[183,126,248,173]	-3	hSpCas9	negative selection	6963436
40681454	40681477	5	-	27260156	L33	viability	CGAGCTACCGAGACCCATGTTGG	PTGER4	ENSG00000171522	-0.19366706978291168	[636]	[586,263,277,552]	-4	hSpCas9	negative selection	7020426
40681509	40681532	5	+	27260156	L33	viability	CGACTGGACCACCAACGTGACGG	PTGER4	ENSG00000171522	0.41358811857743066	[581]	[741,275,565,785]	8	hSpCas9	negative selection	7020427
40691809	40691832	5	-	27260156	L33	viability	CTGACTTCTCGCTCCAAACTTGG	PTGER4	ENSG00000171522	0.18282788516456083	[836]	[797,406,717,871]	4	hSpCas9	negative selection	7020428
40691944	40691967	5	+	27260156	L33	viability	AAATGCCTCTTCTGCCGCATTGG	PTGER4	ENSG00000171522	0.041085450281867386	[791]	[716,334,551,848]	0	hSpCas9	negative selection	7084685
40681539	40681562	5	+	27260156	L33	viability	CGCCTACTCCTACATGTACGCGG	PTGER4	ENSG00000171522	-0.3736353656591056	[880]	[585,274,436,768]	-7	hSpCas9	negative selection	7084686
40681638	40681661	5	-	27260156	L33	viability	GCGAGGTGCGGCGCATGAACTGG	PTGER4	ENSG00000171522	-0.34302235622740995	[173]	[88,59,96,159]	-7	hSpCas9	negative selection	7084687
40681454	40681477	5	-	27260156	K562	viability	CGAGCTACCGAGACCCATGTTGG	PTGER4	ENSG00000171522	-0.6581714647152661	[636]	[603,235,255,349]	-6	hSpCas9	negative selection	7141677
40681509	40681532	5	+	27260156	K562	viability	CGACTGGACCACCAACGTGACGG	PTGER4	ENSG00000171522	-0.4175209363024154	[581]	[479,312,256,486]	-5	hSpCas9	negative selection	7141678
40691809	40691832	5	-	27260156	K562	viability	CTGACTTCTCGCTCCAAACTTGG	PTGER4	ENSG00000171522	0.011435360253165605	[836]	[741,707,1064,502]	0	hSpCas9	negative selection	7141679
40691944	40691967	5	+	27260156	K562	viability	AAATGCCTCTTCTGCCGCATTGG	PTGER4	ENSG00000171522	0.25043817861513884	[791]	[919,1127,403,902]	3	hSpCas9	negative selection	7205936
40681539	40681562	5	+	27260156	K562	viability	CGCCTACTCCTACATGTACGCGG	PTGER4	ENSG00000171522	0.14922274531682045	[880]	[744,1086,842,798]	1	hSpCas9	negative selection	7205937
40681638	40681661	5	-	27260156	K562	viability	GCGAGGTGCGGCGCATGAACTGG	PTGER4	ENSG00000171522	-0.5289154330586836	[173]	[167,178,72,25]	-6	hSpCas9	negative selection	7205938
40681454	40681477	5	-	27260156	HT29	viability	CGAGCTACCGAGACCCATGTTGG	PTGER4	ENSG00000171522	-0.47555179033670036	[636]	[639,560,451,574]	-7	hSpCas9	negative selection	7262928
40681509	40681532	5	+	27260156	HT29	viability	CGACTGGACCACCAACGTGACGG	PTGER4	ENSG00000171522	0.1890224169417945	[581]	[912,1069,622,662]	3	hSpCas9	negative selection	7262929
40691809	40691832	5	-	27260156	HT29	viability	CTGACTTCTCGCTCCAAACTTGG	PTGER4	ENSG00000171522	0.19782562703127682	[836]	[978,1401,1240,1056]	4	hSpCas9	negative selection	7262930
40691944	40691967	5	+	27260156	HT29	viability	AAATGCCTCTTCTGCCGCATTGG	PTGER4	ENSG00000171522	0.1183125772432061	[791]	[1114,952,984,1108]	2	hSpCas9	negative selection	7327187
40681539	40681562	5	+	27260156	HT29	viability	CGCCTACTCCTACATGTACGCGG	PTGER4	ENSG00000171522	-0.09094617688789142	[880]	[1160,915,1034,917]	-2	hSpCas9	negative selection	7327188
40681638	40681661	5	-	27260156	HT29	viability	GCGAGGTGCGGCGCATGAACTGG	PTGER4	ENSG00000171522	-0.4177383131953001	[173]	[260,128,110,138]	-6	hSpCas9	negative selection	7327189
40681454	40681477	5	-	27260156	MHHES1	viability	CGAGCTACCGAGACCCATGTTGG	PTGER4	ENSG00000171522	-0.5229351096941214	[636]	[470,633,602,328]	-7	hSpCas9	negative selection	7384179
40681509	40681532	5	+	27260156	MHHES1	viability	CGACTGGACCACCAACGTGACGG	PTGER4	ENSG00000171522	-0.03772995706748561	[581]	[821,650,497,599]	0	hSpCas9	negative selection	7384180
40691809	40691832	5	-	27260156	MHHES1	viability	CTGACTTCTCGCTCCAAACTTGG	PTGER4	ENSG00000171522	0.1166108413381165	[836]	[988,1192,1086,849]	2	hSpCas9	negative selection	7384181
40691944	40691967	5	+	27260156	MHHES1	viability	AAATGCCTCTTCTGCCGCATTGG	PTGER4	ENSG00000171522	-0.11432696793502095	[791]	[901,972,843,628]	-2	hSpCas9	negative selection	7448438
40681539	40681562	5	+	27260156	MHHES1	viability	CGCCTACTCCTACATGTACGCGG	PTGER4	ENSG00000171522	0.18718295813051733	[880]	[851,745,2516,470]	3	hSpCas9	negative selection	7448439
40681638	40681661	5	-	27260156	MHHES1	viability	GCGAGGTGCGGCGCATGAACTGG	PTGER4	ENSG00000171522	-0.19889548194187867	[173]	[189,211,197,101]	-4	hSpCas9	negative selection	7448440
40681454	40681477	5	-	27260156	MEWO	viability	CGAGCTACCGAGACCCATGTTGG	PTGER4	ENSG00000171522	-0.3987121454117119	[636]	[521,370,476]	-7	hSpCas9	negative selection	7505430
40681509	40681532	5	+	27260156	MEWO	viability	CGACTGGACCACCAACGTGACGG	PTGER4	ENSG00000171522	0.3602905887185563	[581]	[946,654,542]	7	hSpCas9	negative selection	7505431
40691809	40691832	5	-	27260156	MEWO	viability	CTGACTTCTCGCTCCAAACTTGG	PTGER4	ENSG00000171522	0.1750354177609963	[836]	[952,961,749]	4	hSpCas9	negative selection	7505432
40691944	40691967	5	+	27260156	MEWO	viability	AAATGCCTCTTCTGCCGCATTGG	PTGER4	ENSG00000171522	0.17809656125144158	[791]	[909,768,849]	4	hSpCas9	negative selection	7569689
40681539	40681562	5	+	27260156	MEWO	viability	CGCCTACTCCTACATGTACGCGG	PTGER4	ENSG00000171522	-0.21759080488504512	[880]	[755,604,774]	-5	hSpCas9	negative selection	7569690
40681638	40681661	5	-	27260156	MEWO	viability	GCGAGGTGCGGCGCATGAACTGG	PTGER4	ENSG00000171522	0.014277604097672869	[173]	[205,213,80]	0	hSpCas9	negative selection	7569691
40681454	40681477	5	-	27260156	LNCAPCLONEFGC	viability	CGAGCTACCGAGACCCATGTTGG	PTGER4	ENSG00000171522	-0.31901401468342716	[636]	[509,481,504,356]	-5	hSpCas9	negative selection	7626681
40681509	40681532	5	+	27260156	LNCAPCLONEFGC	viability	CGACTGGACCACCAACGTGACGG	PTGER4	ENSG00000171522	-0.13434548098758994	[581]	[570,443,529,383]	-2	hSpCas9	negative selection	7626682
40691809	40691832	5	-	27260156	LNCAPCLONEFGC	viability	CTGACTTCTCGCTCCAAACTTGG	PTGER4	ENSG00000171522	0.21455201143381242	[836]	[627,825,1115,991]	3	hSpCas9	negative selection	7626683
40691944	40691967	5	+	27260156	LNCAPCLONEFGC	viability	AAATGCCTCTTCTGCCGCATTGG	PTGER4	ENSG00000171522	-0.2619158451467217	[791]	[543,687,523,620]	-4	hSpCas9	negative selection	7690940
40681539	40681562	5	+	27260156	LNCAPCLONEFGC	viability	CGCCTACTCCTACATGTACGCGG	PTGER4	ENSG00000171522	-0.16892005405266863	[880]	[693,489,959,746]	-3	hSpCas9	negative selection	7690941
40681638	40681661	5	-	27260156	LNCAPCLONEFGC	viability	GCGAGGTGCGGCGCATGAACTGG	PTGER4	ENSG00000171522	-0.28264182637165725	[173]	[128,99,188,110]	-4	hSpCas9	negative selection	7690942
40681454	40681477	5	-	27260156	PANC0327	viability	CGAGCTACCGAGACCCATGTTGG	PTGER4	ENSG00000171522	0.14097271676301643	[636]	[751,677,540,527]	2	hSpCas9	negative selection	7747932
40681509	40681532	5	+	27260156	PANC0327	viability	CGACTGGACCACCAACGTGACGG	PTGER4	ENSG00000171522	0.6823979057685192	[581]	[1238,634,721,780]	8	hSpCas9	negative selection	7747933
40691809	40691832	5	-	27260156	PANC0327	viability	CTGACTTCTCGCTCCAAACTTGG	PTGER4	ENSG00000171522	0.08917537670757081	[836]	[834,716,969,654]	1	hSpCas9	negative selection	7747934
40691944	40691967	5	+	27260156	PANC0327	viability	AAATGCCTCTTCTGCCGCATTGG	PTGER4	ENSG00000171522	-0.0797830613841547	[791]	[620,694,621,716]	-1	hSpCas9	negative selection	7812191
40681539	40681562	5	+	27260156	PANC0327	viability	CGCCTACTCCTACATGTACGCGG	PTGER4	ENSG00000171522	0.2426637680027135	[880]	[1521,836,847,556]	3	hSpCas9	negative selection	7812192
40681638	40681661	5	-	27260156	PANC0327	viability	GCGAGGTGCGGCGCATGAACTGG	PTGER4	ENSG00000171522	-0.8035643198517035	[173]	[141,38,100,82]	-8	hSpCas9	negative selection	7812193
40681454	40681477	5	-	27260156	NCIH2009	viability	CGAGCTACCGAGACCCATGTTGG	PTGER4	ENSG00000171522	-0.02611448553036405	[636]	[958,784,894]	0	hSpCas9	negative selection	7869183
40681509	40681532	5	+	27260156	NCIH2009	viability	CGACTGGACCACCAACGTGACGG	PTGER4	ENSG00000171522	0.24739099257839442	[581]	[1164,942,825]	3	hSpCas9	negative selection	7869184
40691809	40691832	5	-	27260156	NCIH2009	viability	CTGACTTCTCGCTCCAAACTTGG	PTGER4	ENSG00000171522	0.14382582075307548	[836]	[1331,1277,1271]	2	hSpCas9	negative selection	7869185
40691944	40691967	5	+	27260156	NCIH2009	viability	AAATGCCTCTTCTGCCGCATTGG	PTGER4	ENSG00000171522	-0.13599822625639169	[791]	[1038,820,1168]	-2	hSpCas9	negative selection	7933442
40681539	40681562	5	+	27260156	NCIH2009	viability	CGCCTACTCCTACATGTACGCGG	PTGER4	ENSG00000171522	0.17752780243309618	[880]	[1371,1385,1411]	2	hSpCas9	negative selection	7933443
40681638	40681661	5	-	27260156	NCIH2009	viability	GCGAGGTGCGGCGCATGAACTGG	PTGER4	ENSG00000171522	0.1280624859346804	[173]	[353,321,136]	1	hSpCas9	negative selection	7933444
40681454	40681477	5	-	27260156	NCIH1373	viability	CGAGCTACCGAGACCCATGTTGG	PTGER4	ENSG00000171522	0.15038342482273487	[636]	[984,552,665,271]	1	hSpCas9	negative selection	7990434
40681509	40681532	5	+	27260156	NCIH1373	viability	CGACTGGACCACCAACGTGACGG	PTGER4	ENSG00000171522	0.08187854040401538	[581]	[1132,545,426,195]	0	hSpCas9	negative selection	7990435
40691809	40691832	5	-	27260156	NCIH1373	viability	CTGACTTCTCGCTCCAAACTTGG	PTGER4	ENSG00000171522	0.004415718167869009	[836]	[969,785,1028,261]	0	hSpCas9	negative selection	7990436
40691944	40691967	5	+	27260156	NCIH1373	viability	AAATGCCTCTTCTGCCGCATTGG	PTGER4	ENSG00000171522	0.07834295922312318	[791]	[804,453,1017,402]	0	hSpCas9	negative selection	8054693
40681539	40681562	5	+	27260156	NCIH1373	viability	CGCCTACTCCTACATGTACGCGG	PTGER4	ENSG00000171522	-0.02956424029337068	[880]	[1066,703,676,393]	0	hSpCas9	negative selection	8054694
40681638	40681661	5	-	27260156	NCIH1373	viability	GCGAGGTGCGGCGCATGAACTGG	PTGER4	ENSG00000171522	-0.4034529701958016	[173]	[216,138,135,27]	-4	hSpCas9	negative selection	8054695
40681454	40681477	5	-	27260156	PATU8902	viability	CGAGCTACCGAGACCCATGTTGG	PTGER4	ENSG00000171522	-0.1377981922770623	[636]	[438,990,578,1337]	-1	hSpCas9	negative selection	8111685
40681509	40681532	5	+	27260156	PATU8902	viability	CGACTGGACCACCAACGTGACGG	PTGER4	ENSG00000171522	-0.30366382548585436	[581]	[592,911,518,631]	-3	hSpCas9	negative selection	8111686
40691809	40691832	5	-	27260156	PATU8902	viability	CTGACTTCTCGCTCCAAACTTGG	PTGER4	ENSG00000171522	-0.24664108343127278	[836]	[719,1188,1082,897]	-2	hSpCas9	negative selection	8111687
40691944	40691967	5	+	27260156	PATU8902	viability	AAATGCCTCTTCTGCCGCATTGG	PTGER4	ENSG00000171522	-0.07592116874517674	[791]	[863,1086,875,1444]	0	hSpCas9	negative selection	8175944
40681539	40681562	5	+	27260156	PATU8902	viability	CGCCTACTCCTACATGTACGCGG	PTGER4	ENSG00000171522	-0.49672705514841237	[880]	[1213,966,415,1003]	-5	hSpCas9	negative selection	8175945
40681638	40681661	5	-	27260156	PATU8902	viability	GCGAGGTGCGGCGCATGAACTGG	PTGER4	ENSG00000171522	-0.11127343714657556	[173]	[346,79,186,297]	-1	hSpCas9	negative selection	8175946
40681454	40681477	5	-	27260156	PANC1	viability	CGAGCTACCGAGACCCATGTTGG	PTGER4	ENSG00000171522	-0.13061856756576024	[636]	[419,660,443,499]	-2	hSpCas9	negative selection	8232936
40681509	40681532	5	+	27260156	PANC1	viability	CGACTGGACCACCAACGTGACGG	PTGER4	ENSG00000171522	0.13837833548955353	[581]	[466,780,382,599]	2	hSpCas9	negative selection	8232937
40691809	40691832	5	-	27260156	PANC1	viability	CTGACTTCTCGCTCCAAACTTGG	PTGER4	ENSG00000171522	0.4502237754146543	[836]	[795,1029,1387,753]	7	hSpCas9	negative selection	8232938
40691944	40691967	5	+	27260156	PANC1	viability	AAATGCCTCTTCTGCCGCATTGG	PTGER4	ENSG00000171522	-0.012878779837373067	[791]	[625,1013,549,580]	0	hSpCas9	negative selection	8297195
40681539	40681562	5	+	27260156	PANC1	viability	CGCCTACTCCTACATGTACGCGG	PTGER4	ENSG00000171522	-0.34191283635217196	[880]	[667,863,432,483]	-5	hSpCas9	negative selection	8297196
40681638	40681661	5	-	27260156	PANC1	viability	GCGAGGTGCGGCGCATGAACTGG	PTGER4	ENSG00000171522	-0.7323403492876879	[173]	[114,130,44,76]	-8	hSpCas9	negative selection	8297197
40681454	40681477	5	-	27260156	PANC0813	viability	CGAGCTACCGAGACCCATGTTGG	PTGER4	ENSG00000171522	-0.4004158816089228	[636]	[823,405,678,391]	-6	hSpCas9	negative selection	8354187
40681509	40681532	5	+	27260156	PANC0813	viability	CGACTGGACCACCAACGTGACGG	PTGER4	ENSG00000171522	-0.35236643583268806	[581]	[733,502,527,401]	-5	hSpCas9	negative selection	8354188
40691809	40691832	5	-	27260156	PANC0813	viability	CTGACTTCTCGCTCCAAACTTGG	PTGER4	ENSG00000171522	0.2000469304163408	[836]	[1177,1090,1237,1019]	3	hSpCas9	negative selection	8354189
40691944	40691967	5	+	27260156	PANC0813	viability	AAATGCCTCTTCTGCCGCATTGG	PTGER4	ENSG00000171522	-0.2840148577530545	[791]	[886,621,765,789]	-4	hSpCas9	negative selection	8418446
40681539	40681562	5	+	27260156	PANC0813	viability	CGCCTACTCCTACATGTACGCGG	PTGER4	ENSG00000171522	-0.3463253174468328	[880]	[755,774,925,793]	-5	hSpCas9	negative selection	8418447
40681638	40681661	5	-	27260156	PANC0813	viability	GCGAGGTGCGGCGCATGAACTGG	PTGER4	ENSG00000171522	-0.18774241427705785	[173]	[154,149,170,235]	-3	hSpCas9	negative selection	8418448
40681454	40681477	5	-	27260156	RDES	viability	CGAGCTACCGAGACCCATGTTGG	PTGER4	ENSG00000171522	-0.657388092982987	[636]	[366,421,578,512]	-8	hSpCas9	negative selection	8475438
40681509	40681532	5	+	27260156	RDES	viability	CGACTGGACCACCAACGTGACGG	PTGER4	ENSG00000171522	0.18663822068498054	[581]	[676,713,711,972]	3	hSpCas9	negative selection	8475439
40691809	40691832	5	-	27260156	RDES	viability	CTGACTTCTCGCTCCAAACTTGG	PTGER4	ENSG00000171522	-0.03834088790178347	[836]	[735,932,1061,1056]	0	hSpCas9	negative selection	8475440
40691944	40691967	5	+	27260156	RDES	viability	AAATGCCTCTTCTGCCGCATTGG	PTGER4	ENSG00000171522	-0.29167950590057584	[791]	[645,620,892,847]	-5	hSpCas9	negative selection	8539697
40681539	40681562	5	+	27260156	RDES	viability	CGCCTACTCCTACATGTACGCGG	PTGER4	ENSG00000171522	-0.20407225713536004	[880]	[622,868,913,1192]	-3	hSpCas9	negative selection	8539698
40681638	40681661	5	-	27260156	RDES	viability	GCGAGGTGCGGCGCATGAACTGG	PTGER4	ENSG00000171522	-0.36825187554545247	[173]	[189,160,93,158]	-6	hSpCas9	negative selection	8539699
40681454	40681477	5	-	27260156	PC3	viability	CGAGCTACCGAGACCCATGTTGG	PTGER4	ENSG00000171522	-0.4503242730168961	[636]	[273,495,984,339]	-8	hSpCas9	negative selection	8596689
40681509	40681532	5	+	27260156	PC3	viability	CGACTGGACCACCAACGTGACGG	PTGER4	ENSG00000171522	-0.06919049222384233	[581]	[368,507,920,584]	-1	hSpCas9	negative selection	8596690
40691809	40691832	5	-	27260156	PC3	viability	CTGACTTCTCGCTCCAAACTTGG	PTGER4	ENSG00000171522	0.37782207538351553	[836]	[729,855,2298,977]	7	hSpCas9	negative selection	8596691
40691944	40691967	5	+	27260156	PC3	viability	AAATGCCTCTTCTGCCGCATTGG	PTGER4	ENSG00000171522	-0.04193094363308558	[791]	[428,823,1469,691]	-1	hSpCas9	negative selection	8660948
40681539	40681562	5	+	27260156	PC3	viability	CGCCTACTCCTACATGTACGCGG	PTGER4	ENSG00000171522	-0.05379047771294021	[880]	[453,766,1779,852]	-1	hSpCas9	negative selection	8660949
40681638	40681661	5	-	27260156	PC3	viability	GCGAGGTGCGGCGCATGAACTGG	PTGER4	ENSG00000171522	-0.2939675823766026	[173]	[80,217,231,75]	-6	hSpCas9	negative selection	8660950
40681454	40681477	5	-	27260156	PATU8988T	viability	CGAGCTACCGAGACCCATGTTGG	PTGER4	ENSG00000171522	-0.5003490481512738	[636]	[424,359,515,430]	-7	hSpCas9	negative selection	8717940
40681509	40681532	5	+	27260156	PATU8988T	viability	CGACTGGACCACCAACGTGACGG	PTGER4	ENSG00000171522	-0.20599470111077683	[581]	[517,398,332,711]	-4	hSpCas9	negative selection	8717941
40691809	40691832	5	-	27260156	PATU8988T	viability	CTGACTTCTCGCTCCAAACTTGG	PTGER4	ENSG00000171522	0.20594477674812572	[836]	[864,794,1189,858]	3	hSpCas9	negative selection	8717942
40691944	40691967	5	+	27260156	PATU8988T	viability	AAATGCCTCTTCTGCCGCATTGG	PTGER4	ENSG00000171522	-0.05623700308394097	[791]	[715,668,665,900]	-1	hSpCas9	negative selection	8782199
40681539	40681562	5	+	27260156	PATU8988T	viability	CGCCTACTCCTACATGTACGCGG	PTGER4	ENSG00000171522	-0.40159252194377504	[880]	[478,813,708,585]	-6	hSpCas9	negative selection	8782200
40681638	40681661	5	-	27260156	PATU8988T	viability	GCGAGGTGCGGCGCATGAACTGG	PTGER4	ENSG00000171522	0.8032568328109307	[173]	[258,346,110,478]	9	hSpCas9	negative selection	8782201
40681454	40681477	5	-	27260156	T47D	viability	CGAGCTACCGAGACCCATGTTGG	PTGER4	ENSG00000171522	-0.3360918511922474	[636]	[505,515,617,720]	-6	hSpCas9	negative selection	8839191
40681509	40681532	5	+	27260156	T47D	viability	CGACTGGACCACCAACGTGACGG	PTGER4	ENSG00000171522	-0.14249668014536118	[581]	[723,490,569,685]	-3	hSpCas9	negative selection	8839192
40691809	40691832	5	-	27260156	T47D	viability	CTGACTTCTCGCTCCAAACTTGG	PTGER4	ENSG00000171522	0.067200823219974	[836]	[1058,1026,985,1013]	1	hSpCas9	negative selection	8839193
40691944	40691967	5	+	27260156	T47D	viability	AAATGCCTCTTCTGCCGCATTGG	PTGER4	ENSG00000171522	-0.14359507438506758	[791]	[855,687,819,994]	-3	hSpCas9	negative selection	8903450
40681539	40681562	5	+	27260156	T47D	viability	CGCCTACTCCTACATGTACGCGG	PTGER4	ENSG00000171522	-0.16160341491074182	[880]	[876,856,1011,927]	-4	hSpCas9	negative selection	8903451
40681638	40681661	5	-	27260156	T47D	viability	GCGAGGTGCGGCGCATGAACTGG	PTGER4	ENSG00000171522	-0.04554986927557336	[173]	[253,185,179,165]	-1	hSpCas9	negative selection	8903452
40681454	40681477	5	-	27260156	SU8686	viability	CGAGCTACCGAGACCCATGTTGG	PTGER4	ENSG00000171522	-0.1875162107425435	[636]	[531,564,380,766]	-3	hSpCas9	negative selection	8960442
40681509	40681532	5	+	27260156	SU8686	viability	CGACTGGACCACCAACGTGACGG	PTGER4	ENSG00000171522	0.5329212903024338	[581]	[663,712,934,1102]	8	hSpCas9	negative selection	8960443
40691809	40691832	5	-	27260156	SU8686	viability	CTGACTTCTCGCTCCAAACTTGG	PTGER4	ENSG00000171522	0.27818017696940145	[836]	[861,1062,931,1198]	5	hSpCas9	negative selection	8960444
40691944	40691967	5	+	27260156	SU8686	viability	AAATGCCTCTTCTGCCGCATTGG	PTGER4	ENSG00000171522	0.07991253287682965	[791]	[719,585,1022,1073]	1	hSpCas9	negative selection	9024701
40681539	40681562	5	+	27260156	SU8686	viability	CGCCTACTCCTACATGTACGCGG	PTGER4	ENSG00000171522	-0.15531821365938692	[880]	[610,737,825,1021]	-3	hSpCas9	negative selection	9024702
40681638	40681661	5	-	27260156	SU8686	viability	GCGAGGTGCGGCGCATGAACTGG	PTGER4	ENSG00000171522	-0.4969776586679979	[173]	[103,125,131,128]	-7	hSpCas9	negative selection	9024703
40681454	40681477	5	-	27260156	SKES1	viability	CGAGCTACCGAGACCCATGTTGG	PTGER4	ENSG00000171522	-0.5368914138987269	[636]	[415,541,343,453]	-8	hSpCas9	negative selection	9081693
40681509	40681532	5	+	27260156	SKES1	viability	CGACTGGACCACCAACGTGACGG	PTGER4	ENSG00000171522	-0.02698918548433976	[581]	[614,694,483,508]	0	hSpCas9	negative selection	9081694
40691809	40691832	5	-	27260156	SKES1	viability	CTGACTTCTCGCTCCAAACTTGG	PTGER4	ENSG00000171522	0.2616260328235138	[836]	[1472,935,878,789]	5	hSpCas9	negative selection	9081695
40691944	40691967	5	+	27260156	SKES1	viability	AAATGCCTCTTCTGCCGCATTGG	PTGER4	ENSG00000171522	-0.049244670710617555	[791]	[810,1035,642,614]	-1	hSpCas9	negative selection	9145952
40681539	40681562	5	+	27260156	SKES1	viability	CGCCTACTCCTACATGTACGCGG	PTGER4	ENSG00000171522	-0.25574852398955894	[880]	[906,853,472,742]	-5	hSpCas9	negative selection	9145953
40681638	40681661	5	-	27260156	SKES1	viability	GCGAGGTGCGGCGCATGAACTGG	PTGER4	ENSG00000171522	-0.037660778565561825	[173]	[195,325,97,87]	-1	hSpCas9	negative selection	9145954
40681454	40681477	5	-	27260156	TOV112D	viability	CGAGCTACCGAGACCCATGTTGG	PTGER4	ENSG00000171522	-0.368442794682439	[636]	[401,578,619,390]	-6	hSpCas9	negative selection	9202944
40681509	40681532	5	+	27260156	TOV112D	viability	CGACTGGACCACCAACGTGACGG	PTGER4	ENSG00000171522	0.04356928915252983	[581]	[609,852,402,598]	0	hSpCas9	negative selection	9202945
40691809	40691832	5	-	27260156	TOV112D	viability	CTGACTTCTCGCTCCAAACTTGG	PTGER4	ENSG00000171522	0.1010956149493829	[836]	[801,1284,808,788]	2	hSpCas9	negative selection	9202946
40691944	40691967	5	+	27260156	TOV112D	viability	AAATGCCTCTTCTGCCGCATTGG	PTGER4	ENSG00000171522	0.02009355958855752	[791]	[833,1023,804,614]	0	hSpCas9	negative selection	9267203
40681539	40681562	5	+	27260156	TOV112D	viability	CGCCTACTCCTACATGTACGCGG	PTGER4	ENSG00000171522	-0.5399725382831173	[880]	[698,650,628,469]	-8	hSpCas9	negative selection	9267204
40681638	40681661	5	-	27260156	TOV112D	viability	GCGAGGTGCGGCGCATGAACTGG	PTGER4	ENSG00000171522	-0.12582561813565074	[173]	[141,256,136,125]	-2	hSpCas9	negative selection	9267205
40681454	40681477	5	-	27260156	TC71	viability	CGAGCTACCGAGACCCATGTTGG	PTGER4	ENSG00000171522	-0.2594200823258068	[636]	[528,525,583,647]	-6	hSpCas9	negative selection	9324195
40681509	40681532	5	+	27260156	TC71	viability	CGACTGGACCACCAACGTGACGG	PTGER4	ENSG00000171522	-0.000934660129976117	[581]	[599,514,722,654]	0	hSpCas9	negative selection	9324196
40691809	40691832	5	-	27260156	TC71	viability	CTGACTTCTCGCTCCAAACTTGG	PTGER4	ENSG00000171522	0.22394246745931645	[836]	[968,988,1050,1192]	5	hSpCas9	negative selection	9324197
40691944	40691967	5	+	27260156	TC71	viability	AAATGCCTCTTCTGCCGCATTGG	PTGER4	ENSG00000171522	0.11457252630610582	[791]	[899,914,923,938]	3	hSpCas9	negative selection	9388454
40681539	40681562	5	+	27260156	TC71	viability	CGCCTACTCCTACATGTACGCGG	PTGER4	ENSG00000171522	-0.24920229969549934	[880]	[732,793,761,897]	-6	hSpCas9	negative selection	9388455
40681638	40681661	5	-	27260156	TC71	viability	GCGAGGTGCGGCGCATGAACTGG	PTGER4	ENSG00000171522	-0.061411282334576045	[173]	[166,176,179,191]	-1	hSpCas9	negative selection	9388456
40681454	40681477	5	-	27260156	TC32	viability	CGAGCTACCGAGACCCATGTTGG	PTGER4	ENSG00000171522	-0.5091951223275448	[636]	[395,323,478,512]	-7	hSpCas9	negative selection	9445446
40681509	40681532	5	+	27260156	TC32	viability	CGACTGGACCACCAACGTGACGG	PTGER4	ENSG00000171522	-0.022034825833489424	[581]	[513,396,670,624]	0	hSpCas9	negative selection	9445447
40691809	40691832	5	-	27260156	TC32	viability	CTGACTTCTCGCTCCAAACTTGG	PTGER4	ENSG00000171522	0.1096714867314238	[836]	[726,733,986,984]	2	hSpCas9	negative selection	9445448
40691944	40691967	5	+	27260156	TC32	viability	AAATGCCTCTTCTGCCGCATTGG	PTGER4	ENSG00000171522	-0.28219125954402996	[791]	[787,285,900,587]	-5	hSpCas9	negative selection	9509705
40681539	40681562	5	+	27260156	TC32	viability	CGCCTACTCCTACATGTACGCGG	PTGER4	ENSG00000171522	-0.05486585112694842	[880]	[626,766,904,895]	-1	hSpCas9	negative selection	9509706
40681638	40681661	5	-	27260156	TC32	viability	GCGAGGTGCGGCGCATGAACTGG	PTGER4	ENSG00000171522	-0.11159959422588228	[173]	[107,116,211,190]	-2	hSpCas9	negative selection	9509707
40681231	40681254	5	+	27869803	HPAFII	viability after 27 days	TACATGAAGGGCCAATGGCCCGG	PTGER4	ENSG00000171522	1.286425044173357	[93]	[167,80,NaN]	9	hSpCas9	negative selection	9591905
40681359	40681382	5	-	27869803	HPAFII	viability after 27 days	AGTGGCTGTAGAAATAGGCATGG	PTGER4	ENSG00000171522	-0.4596125234544022	[296]	[178,58,NaN]	-3	hSpCas9	negative selection	9591906
40681589	40681612	5	-	27869803	HPAFII	viability after 27 days	CACAAGCACGTTGCAGAGGACGG	PTGER4	ENSG00000171522	0.474682564213437	[357]	[218,296,NaN]	4	hSpCas9	negative selection	9591907
40681745	40681768	5	+	27869803	HPAFII	viability after 27 days	TCAGCGACTTTCGGCGCCGCCGG	PTGER4	ENSG00000171522	1.6307690365574852	[109]	[105,239,NaN]	9	hSpCas9	negative selection	9591908
40691901	40691924	5	-	27869803	HPAFII	viability after 27 days	TGAGCACTGTCTTTCTCAGGAGG	PTGER4	ENSG00000171522	0.42479246654402425	[151]	[205,24,NaN]	3	hSpCas9	negative selection	9591909
40681231	40681254	5	+	27869803	HPAFII	viability after 15 days	TACATGAAGGGCCAATGGCCCGG	PTGER4	ENSG00000171522	0.5759708182298482	[93]	[276,71,NaN]	6	hSpCas9	negative selection	9674354
40681359	40681382	5	-	27869803	HPAFII	viability after 15 days	AGTGGCTGTAGAAATAGGCATGG	PTGER4	ENSG00000171522	-0.43067987116037865	[296]	[213,250,NaN]	-5	hSpCas9	negative selection	9674355
40681589	40681612	5	-	27869803	HPAFII	viability after 15 days	CACAAGCACGTTGCAGAGGACGG	PTGER4	ENSG00000171522	0.45385458050122407	[357]	[645,452,NaN]	5	hSpCas9	negative selection	9674356
40681745	40681768	5	+	27869803	HPAFII	viability after 15 days	TCAGCGACTTTCGGCGCCGCCGG	PTGER4	ENSG00000171522	1.5906858020246997	[109]	[397,329,NaN]	9	hSpCas9	negative selection	9674357
40691901	40691924	5	-	27869803	HPAFII	viability after 15 days	TGAGCACTGTCTTTCTCAGGAGG	PTGER4	ENSG00000171522	0.00838305574048226	[151]	[278,92,NaN]	0	hSpCas9	negative selection	9674358
40681231	40681254	5	+	27869803	ASPC1	viability after 36 days	TACATGAAGGGCCAATGGCCCGG	PTGER4	ENSG00000171522	-0.32747820655609283	[327]	[8,191,67]	-3	hSpCas9	negative selection	9756803
40681359	40681382	5	-	27869803	ASPC1	viability after 36 days	AGTGGCTGTAGAAATAGGCATGG	PTGER4	ENSG00000171522	0.30729034801308275	[489]	[122,384,133]	3	hSpCas9	negative selection	9756804
40681589	40681612	5	-	27869803	ASPC1	viability after 36 days	CACAAGCACGTTGCAGAGGACGG	PTGER4	ENSG00000171522	0.306341058931732	[829]	[420,208,428]	3	hSpCas9	negative selection	9756805
40681745	40681768	5	+	27869803	ASPC1	viability after 36 days	TCAGCGACTTTCGGCGCCGCCGG	PTGER4	ENSG00000171522	-1.5410935640854693	[675]	[105,76,65]	-8	hSpCas9	negative selection	9756806
40691901	40691924	5	-	27869803	ASPC1	viability after 36 days	TGAGCACTGTCTTTCTCAGGAGG	PTGER4	ENSG00000171522	-0.34235598361667935	[669]	[229,188,146]	-4	hSpCas9	negative selection	9756807
40681231	40681254	5	+	27869803	PATU8988S	viability after 35 days	TACATGAAGGGCCAATGGCCCGG	PTGER4	ENSG00000171522	0.29566140140137653	[183]	[73,107,NaN]	3	hSpCas9	negative selection	9839252
40681359	40681382	5	-	27869803	PATU8988S	viability after 35 days	AGTGGCTGTAGAAATAGGCATGG	PTGER4	ENSG00000171522	-0.3166550572849785	[441]	[113,171,NaN]	-3	hSpCas9	negative selection	9839253
40681589	40681612	5	-	27869803	PATU8988S	viability after 35 days	CACAAGCACGTTGCAGAGGACGG	PTGER4	ENSG00000171522	0.4538446092173918	[750]	[537,289,NaN]	5	hSpCas9	negative selection	9839254
40681745	40681768	5	+	27869803	PATU8988S	viability after 35 days	TCAGCGACTTTCGGCGCCGCCGG	PTGER4	ENSG00000171522	1.3630475161186524	[385]	[351,447,NaN]	9	hSpCas9	negative selection	9839255
40691901	40691924	5	-	27869803	PATU8988S	viability after 35 days	TGAGCACTGTCTTTCTCAGGAGG	PTGER4	ENSG00000171522	-0.6706531508152082	[497]	[126,124,NaN]	-6	hSpCas9	negative selection	9839256
40681231	40681254	5	+	27869803	PATU8988S	viability after 31 days	TACATGAAGGGCCAATGGCCCGG	PTGER4	ENSG00000171522	-0.43791235380590154	[183]	[58,47,NaN]	-5	hSpCas9	negative selection	9921701
40681359	40681382	5	-	27869803	PATU8988S	viability after 31 days	AGTGGCTGTAGAAATAGGCATGG	PTGER4	ENSG00000171522	-0.19662577733011272	[441]	[100,220,NaN]	-2	hSpCas9	negative selection	9921702
40681589	40681612	5	-	27869803	PATU8988S	viability after 31 days	CACAAGCACGTTGCAGAGGACGG	PTGER4	ENSG00000171522	0.42052210017478786	[750]	[380,425,NaN]	5	hSpCas9	negative selection	9921703
40681745	40681768	5	+	27869803	PATU8988S	viability after 31 days	TCAGCGACTTTCGGCGCCGCCGG	PTGER4	ENSG00000171522	0.9519815858905171	[385]	[262,341,NaN]	9	hSpCas9	negative selection	9921704
40691901	40691924	5	-	27869803	PATU8988S	viability after 31 days	TGAGCACTGTCTTTCTCAGGAGG	PTGER4	ENSG00000171522	-0.3773447765959165	[497]	[118,195,NaN]	-4	hSpCas9	negative selection	9921705
40681231	40681254	5	+	27869803	HPAFII	viability after 35 days	TACATGAAGGGCCAATGGCCCGG	PTGER4	ENSG00000171522	1.4042817145324282	[93]	[156,90,NaN]	8	hSpCas9	negative selection	10004150
40681359	40681382	5	-	27869803	HPAFII	viability after 35 days	AGTGGCTGTAGAAATAGGCATGG	PTGER4	ENSG00000171522	0.30456565878103803	[296]	[283,74,NaN]	2	hSpCas9	negative selection	10004151
40681589	40681612	5	-	27869803	HPAFII	viability after 35 days	CACAAGCACGTTGCAGAGGACGG	PTGER4	ENSG00000171522	1.636013203033638	[357]	[440,700,NaN]	9	hSpCas9	negative selection	10004152
40681745	40681768	5	+	27869803	HPAFII	viability after 35 days	TCAGCGACTTTCGGCGCCGCCGG	PTGER4	ENSG00000171522	1.5064211349636147	[109]	[105,216,NaN]	8	hSpCas9	negative selection	10004153
40691901	40691924	5	-	27869803	HPAFII	viability after 35 days	TGAGCACTGTCTTTCTCAGGAGG	PTGER4	ENSG00000171522	0.9027786598086154	[151]	[236,38,NaN]	6	hSpCas9	negative selection	10004154
40681231	40681254	5	+	27869803	HPAFII	viability after 31 days	TACATGAAGGGCCAATGGCCCGG	PTGER4	ENSG00000171522	1.1938934504111074	[93]	[202,30,NaN]	8	hSpCas9	negative selection	10086599
40681359	40681382	5	-	27869803	HPAFII	viability after 31 days	AGTGGCTGTAGAAATAGGCATGG	PTGER4	ENSG00000171522	0.2588837242422203	[296]	[320,66,NaN]	1	hSpCas9	negative selection	10086600
40681589	40681612	5	-	27869803	HPAFII	viability after 31 days	CACAAGCACGTTGCAGAGGACGG	PTGER4	ENSG00000171522	1.0751407887262714	[357]	[340,512,NaN]	7	hSpCas9	negative selection	10086601
40681745	40681768	5	+	27869803	HPAFII	viability after 31 days	TCAGCGACTTTCGGCGCCGCCGG	PTGER4	ENSG00000171522	1.736810190585382	[109]	[110,308,NaN]	9	hSpCas9	negative selection	10086602
40691901	40691924	5	-	27869803	HPAFII	viability after 31 days	TGAGCACTGTCTTTCTCAGGAGG	PTGER4	ENSG00000171522	1.2059253676325883	[151]	[325,55,NaN]	8	hSpCas9	negative selection	10086603
40681068	40681091	5	+	28162770	P31FUJ	viability	GGTGATGTTCATCTTCGGGGTGG	PTGER4	ENSG00000171522	-0.9571677618009513	[75]	[45]	-6	hSpCas9	negative selection	10219471
40681233	40681256	5	+	28162770	P31FUJ	viability	CATGAAGGGCCAATGGCCCGGGG	PTGER4	ENSG00000171522	0.9604732843053145	[142]	[326]	9	hSpCas9	negative selection	10219472
40680998	40681021	5	-	28162770	P31FUJ	viability	GGACGAATTGACCCCGGGAGTGG	PTGER4	ENSG00000171522	-0.07181032774207408	[143]	[160]	0	hSpCas9	negative selection	10219473
40681022	40681045	5	-	28162770	P31FUJ	viability	CAGCCGGTCGGGGCTCAAGGAGG	PTGER4	ENSG00000171522	0.7340309316504219	[21]	[42]	8	hSpCas9	negative selection	10219474
40681047	40681070	5	+	28162770	P31FUJ	viability	CAGCCCAGTGACCATCCCGGCGG	PTGER4	ENSG00000171522	-0.544746210729119	[107]	[86]	-4	hSpCas9	negative selection	10219475
40681143	40681166	5	+	28162770	P31FUJ	viability	GGAGACGACCTTCTACACGCTGG	PTGER4	ENSG00000171522	0.5392458489072729	[64]	[110]	6	hSpCas9	negative selection	10219476
40681261	40681284	5	-	28162770	P31FUJ	viability	AAGGTGCTGTACTCGCACAGCGG	PTGER4	ENSG00000171522	0.25262462275586295	[109]	[153]	2	hSpCas9	negative selection	10219477
40681586	40681609	5	-	28162770	P31FUJ	viability	AAGCACGTTGCAGAGGACGGTGG	PTGER4	ENSG00000171522	-0.33971740833089026	[41]	[38]	-3	hSpCas9	negative selection	10219478
40681727	40681750	5	-	28162770	P31FUJ	viability	GCTGAGGCGCGGCAAGGCTGGGG	PTGER4	ENSG00000171522	-0.441044137407793	[185]	[160]	-4	hSpCas9	negative selection	10219479
40681820	40681843	5	-	28162770	P31FUJ	viability	GATGAGCACCACCAGGGAGGTGG	PTGER4	ENSG00000171522	-0.7108495012190229	[311]	[223]	-5	hSpCas9	negative selection	10219480
40681068	40681091	5	+	28162770	TF1	viability	GGTGATGTTCATCTTCGGGGTGG	PTGER4	ENSG00000171522	NaN	[NaN]	[128]	1	hSpCas9	negative selection	10388837
40681233	40681256	5	+	28162770	TF1	viability	CATGAAGGGCCAATGGCCCGGGG	PTGER4	ENSG00000171522	NaN	[NaN]	[105]	1	hSpCas9	negative selection	10388838
40680998	40681021	5	-	28162770	TF1	viability	GGACGAATTGACCCCGGGAGTGG	PTGER4	ENSG00000171522	NaN	[NaN]	[160]	1	hSpCas9	negative selection	10388839
40681022	40681045	5	-	28162770	TF1	viability	CAGCCGGTCGGGGCTCAAGGAGG	PTGER4	ENSG00000171522	NaN	[NaN]	[0]	1	hSpCas9	negative selection	10388840
40681047	40681070	5	+	28162770	TF1	viability	CAGCCCAGTGACCATCCCGGCGG	PTGER4	ENSG00000171522	NaN	[NaN]	[46]	1	hSpCas9	negative selection	10388841
40681143	40681166	5	+	28162770	TF1	viability	GGAGACGACCTTCTACACGCTGG	PTGER4	ENSG00000171522	NaN	[NaN]	[67]	1	hSpCas9	negative selection	10388842
40681261	40681284	5	-	28162770	TF1	viability	AAGGTGCTGTACTCGCACAGCGG	PTGER4	ENSG00000171522	NaN	[NaN]	[151]	1	hSpCas9	negative selection	10388843
40681586	40681609	5	-	28162770	TF1	viability	AAGCACGTTGCAGAGGACGGTGG	PTGER4	ENSG00000171522	NaN	[NaN]	[6]	1	hSpCas9	negative selection	10388844
40681727	40681750	5	-	28162770	TF1	viability	GCTGAGGCGCGGCAAGGCTGGGG	PTGER4	ENSG00000171522	NaN	[NaN]	[97]	1	hSpCas9	negative selection	10388845
40681820	40681843	5	-	28162770	TF1	viability	GATGAGCACCACCAGGGAGGTGG	PTGER4	ENSG00000171522	NaN	[NaN]	[184]	1	hSpCas9	negative selection	10388846
40681068	40681091	5	+	28162770	SKM1	viability	GGTGATGTTCATCTTCGGGGTGG	PTGER4	ENSG00000171522	1.0999957899767212	[18]	[71]	8	hSpCas9	negative selection	10558203
40681233	40681256	5	+	28162770	SKM1	viability	CATGAAGGGCCAATGGCCCGGGG	PTGER4	ENSG00000171522	0.8874081736236394	[36]	[120]	8	hSpCas9	negative selection	10558204
40680998	40681021	5	-	28162770	SKM1	viability	GGACGAATTGACCCCGGGAGTGG	PTGER4	ENSG00000171522	0.48465964021204627	[37]	[93]	5	hSpCas9	negative selection	10558205
40681022	40681045	5	-	28162770	SKM1	viability	CAGCCGGTCGGGGCTCAAGGAGG	PTGER4	ENSG00000171522	-2.991926699464318	[8]	[1]	-9	hSpCas9	negative selection	10558206
40681047	40681070	5	+	28162770	SKM1	viability	CAGCCCAGTGACCATCCCGGCGG	PTGER4	ENSG00000171522	-0.6125483323930556	[31]	[36]	-5	hSpCas9	negative selection	10558207
40681143	40681166	5	+	28162770	SKM1	viability	GGAGACGACCTTCTACACGCTGG	PTGER4	ENSG00000171522	0.7254860972804877	[25]	[75]	7	hSpCas9	negative selection	10558208
40681261	40681284	5	-	28162770	SKM1	viability	AAGGTGCTGTACTCGCACAGCGG	PTGER4	ENSG00000171522	-0.6520766965796931	[39]	[44]	-5	hSpCas9	negative selection	10558209
40681586	40681609	5	-	28162770	SKM1	viability	AAGCACGTTGCAGAGGACGGTGG	PTGER4	ENSG00000171522	-0.8220016980220055	[16]	[16]	-6	hSpCas9	negative selection	10558210
40681727	40681750	5	-	28162770	SKM1	viability	GCTGAGGCGCGGCAAGGCTGGGG	PTGER4	ENSG00000171522	-0.20666554825733047	[46]	[71]	-2	hSpCas9	negative selection	10558211
40681820	40681843	5	-	28162770	SKM1	viability	GATGAGCACCACCAGGGAGGTGG	PTGER4	ENSG00000171522	-0.1743034419528866	[59]	[93]	-1	hSpCas9	negative selection	10558212
40681068	40681091	5	+	28162770	SKM1	viability	GGTGATGTTCATCTTCGGGGTGG	PTGER4	ENSG00000171522	1.0999957899767212	[18]	[71]	8	hSpCas9	negative selection	10727569
40681233	40681256	5	+	28162770	SKM1	viability	CATGAAGGGCCAATGGCCCGGGG	PTGER4	ENSG00000171522	0.8874081736236394	[36]	[120]	8	hSpCas9	negative selection	10727570
40680998	40681021	5	-	28162770	SKM1	viability	GGACGAATTGACCCCGGGAGTGG	PTGER4	ENSG00000171522	0.48465964021204627	[37]	[93]	5	hSpCas9	negative selection	10727571
40681022	40681045	5	-	28162770	SKM1	viability	CAGCCGGTCGGGGCTCAAGGAGG	PTGER4	ENSG00000171522	-2.991926699464318	[8]	[1]	-9	hSpCas9	negative selection	10727572
40681047	40681070	5	+	28162770	SKM1	viability	CAGCCCAGTGACCATCCCGGCGG	PTGER4	ENSG00000171522	-0.6125483323930556	[31]	[36]	-5	hSpCas9	negative selection	10727573
40681143	40681166	5	+	28162770	SKM1	viability	GGAGACGACCTTCTACACGCTGG	PTGER4	ENSG00000171522	0.7254860972804877	[25]	[75]	7	hSpCas9	negative selection	10727574
40681261	40681284	5	-	28162770	SKM1	viability	AAGGTGCTGTACTCGCACAGCGG	PTGER4	ENSG00000171522	-0.6520766965796931	[39]	[44]	-5	hSpCas9	negative selection	10727575
40681586	40681609	5	-	28162770	SKM1	viability	AAGCACGTTGCAGAGGACGGTGG	PTGER4	ENSG00000171522	-0.8220016980220055	[16]	[16]	-6	hSpCas9	negative selection	10727576
40681727	40681750	5	-	28162770	SKM1	viability	GCTGAGGCGCGGCAAGGCTGGGG	PTGER4	ENSG00000171522	-0.20666554825733047	[46]	[71]	-2	hSpCas9	negative selection	10727577
40681820	40681843	5	-	28162770	SKM1	viability	GATGAGCACCACCAGGGAGGTGG	PTGER4	ENSG00000171522	-0.1743034419528866	[59]	[93]	-1	hSpCas9	negative selection	10727578
40681068	40681091	5	+	28162770	PL21	viability	GGTGATGTTCATCTTCGGGGTGG	PTGER4	ENSG00000171522	-1.3441809017344903	[104]	[17]	-7	hSpCas9	negative selection	10896935
40681233	40681256	5	+	28162770	PL21	viability	CATGAAGGGCCAATGGCCCGGGG	PTGER4	ENSG00000171522	0.18633381496428958	[104]	[51]	1	hSpCas9	negative selection	10896936
40680998	40681021	5	-	28162770	PL21	viability	GGACGAATTGACCCCGGGAGTGG	PTGER4	ENSG00000171522	-0.07839588488466154	[130]	[53]	0	hSpCas9	negative selection	10896937
40681022	40681045	5	-	28162770	PL21	viability	CAGCCGGTCGGGGCTCAAGGAGG	PTGER4	ENSG00000171522	0.3521427079343704	[26]	[14]	3	hSpCas9	negative selection	10896938
40681047	40681070	5	+	28162770	PL21	viability	CAGCCCAGTGACCATCCCGGCGG	PTGER4	ENSG00000171522	0.5277142725178245	[101]	[63]	4	hSpCas9	negative selection	10896939
40681143	40681166	5	+	28162770	PL21	viability	GGAGACGACCTTCTACACGCTGG	PTGER4	ENSG00000171522	-2.4243512504184737	[110]	[8]	-9	hSpCas9	negative selection	10896940
40681261	40681284	5	-	28162770	PL21	viability	AAGGTGCTGTACTCGCACAGCGG	PTGER4	ENSG00000171522	-1.7847534931204716	[94]	[11]	-8	hSpCas9	negative selection	10896941
40681586	40681609	5	-	28162770	PL21	viability	AAGCACGTTGCAGAGGACGGTGG	PTGER4	ENSG00000171522	1.9906862488603703	[36]	[63]	9	hSpCas9	negative selection	10896942
40681727	40681750	5	-	28162770	PL21	viability	GCTGAGGCGCGGCAAGGCTGGGG	PTGER4	ENSG00000171522	-1.849103904530529	[148]	[17]	-8	hSpCas9	negative selection	10896943
40681820	40681843	5	-	28162770	PL21	viability	GATGAGCACCACCAGGGAGGTGG	PTGER4	ENSG00000171522	-0.4794597603699114	[188]	[58]	-3	hSpCas9	negative selection	10896944
40681068	40681091	5	+	28162770	P31FUJ	viability	GGTGATGTTCATCTTCGGGGTGG	PTGER4	ENSG00000171522	-0.9571677618009513	[75]	[45]	-6	hSpCas9	negative selection	11066301
40681233	40681256	5	+	28162770	P31FUJ	viability	CATGAAGGGCCAATGGCCCGGGG	PTGER4	ENSG00000171522	0.9604732843053145	[142]	[326]	9	hSpCas9	negative selection	11066302
40680998	40681021	5	-	28162770	P31FUJ	viability	GGACGAATTGACCCCGGGAGTGG	PTGER4	ENSG00000171522	-0.07181032774207408	[143]	[160]	0	hSpCas9	negative selection	11066303
40681022	40681045	5	-	28162770	P31FUJ	viability	CAGCCGGTCGGGGCTCAAGGAGG	PTGER4	ENSG00000171522	0.7340309316504219	[21]	[42]	8	hSpCas9	negative selection	11066304
40681047	40681070	5	+	28162770	P31FUJ	viability	CAGCCCAGTGACCATCCCGGCGG	PTGER4	ENSG00000171522	-0.544746210729119	[107]	[86]	-4	hSpCas9	negative selection	11066305
40681143	40681166	5	+	28162770	P31FUJ	viability	GGAGACGACCTTCTACACGCTGG	PTGER4	ENSG00000171522	0.5392458489072729	[64]	[110]	6	hSpCas9	negative selection	11066306
40681261	40681284	5	-	28162770	P31FUJ	viability	AAGGTGCTGTACTCGCACAGCGG	PTGER4	ENSG00000171522	0.25262462275586295	[109]	[153]	2	hSpCas9	negative selection	11066307
40681586	40681609	5	-	28162770	P31FUJ	viability	AAGCACGTTGCAGAGGACGGTGG	PTGER4	ENSG00000171522	-0.33971740833089026	[41]	[38]	-3	hSpCas9	negative selection	11066308
40681727	40681750	5	-	28162770	P31FUJ	viability	GCTGAGGCGCGGCAAGGCTGGGG	PTGER4	ENSG00000171522	-0.441044137407793	[185]	[160]	-4	hSpCas9	negative selection	11066309
40681820	40681843	5	-	28162770	P31FUJ	viability	GATGAGCACCACCAGGGAGGTGG	PTGER4	ENSG00000171522	-0.7108495012190229	[311]	[223]	-5	hSpCas9	negative selection	11066310
40681068	40681091	5	+	28162770	OCIAML5	viability	GGTGATGTTCATCTTCGGGGTGG	PTGER4	ENSG00000171522	0.9166078830295477	[26]	[91]	7	hSpCas9	negative selection	11235667
40681233	40681256	5	+	28162770	OCIAML5	viability	CATGAAGGGCCAATGGCCCGGGG	PTGER4	ENSG00000171522	0.42255580924500846	[61]	[149]	3	hSpCas9	negative selection	11235668
40680998	40681021	5	-	28162770	OCIAML5	viability	GGACGAATTGACCCCGGGAGTGG	PTGER4	ENSG00000171522	0.45411878747761836	[128]	[318]	4	hSpCas9	negative selection	11235669
40681022	40681045	5	-	28162770	OCIAML5	viability	CAGCCGGTCGGGGCTCAAGGAGG	PTGER4	ENSG00000171522	-0.16854023565925114	[32]	[52]	-1	hSpCas9	negative selection	11235670
40681047	40681070	5	+	28162770	OCIAML5	viability	CAGCCCAGTGACCATCCCGGCGG	PTGER4	ENSG00000171522	-0.15162685272290477	[31]	[51]	-1	hSpCas9	negative selection	11235671
40681143	40681166	5	+	28162770	OCIAML5	viability	GGAGACGACCTTCTACACGCTGG	PTGER4	ENSG00000171522	0.5339918614430811	[43]	[114]	4	hSpCas9	negative selection	11235672
40681261	40681284	5	-	28162770	OCIAML5	viability	AAGGTGCTGTACTCGCACAGCGG	PTGER4	ENSG00000171522	0.3142918155581232	[89]	[201]	2	hSpCas9	negative selection	11235673
40681586	40681609	5	-	28162770	OCIAML5	viability	AAGCACGTTGCAGAGGACGGTGG	PTGER4	ENSG00000171522	-2.463501282946344	[54]	[17]	-8	hSpCas9	negative selection	11235674
40681727	40681750	5	-	28162770	OCIAML5	viability	GCTGAGGCGCGGCAAGGCTGGGG	PTGER4	ENSG00000171522	-0.1048326412439638	[111]	[187]	-1	hSpCas9	negative selection	11235675
40681820	40681843	5	-	28162770	OCIAML5	viability	GATGAGCACCACCAGGGAGGTGG	PTGER4	ENSG00000171522	-0.24110886160989634	[109]	[167]	-2	hSpCas9	negative selection	11235676
40681068	40681091	5	+	28162770	EOL1	viability	GGTGATGTTCATCTTCGGGGTGG	PTGER4	ENSG00000171522	-0.6306673857565697	[143]	[48]	-4	hSpCas9	negative selection	11405033
40681233	40681256	5	+	28162770	EOL1	viability	CATGAAGGGCCAATGGCCCGGGG	PTGER4	ENSG00000171522	-0.022210207152486117	[132]	[68]	0	hSpCas9	negative selection	11405034
40680998	40681021	5	-	28162770	EOL1	viability	GGACGAATTGACCCCGGGAGTGG	PTGER4	ENSG00000171522	1.3431518858695708	[201]	[269]	9	hSpCas9	negative selection	11405035
40681022	40681045	5	-	28162770	EOL1	viability	CAGCCGGTCGGGGCTCAAGGAGG	PTGER4	ENSG00000171522	0.2464758664578972	[39]	[24]	2	hSpCas9	negative selection	11405036
40681047	40681070	5	+	28162770	EOL1	viability	CAGCCCAGTGACCATCCCGGCGG	PTGER4	ENSG00000171522	-0.15517942090019965	[185]	[87]	-1	hSpCas9	negative selection	11405037
40681143	40681166	5	+	28162770	EOL1	viability	GGAGACGACCTTCTACACGCTGG	PTGER4	ENSG00000171522	-1.6769028519391909	[175]	[28]	-8	hSpCas9	negative selection	11405038
40681261	40681284	5	-	28162770	EOL1	viability	AAGGTGCTGTACTCGCACAGCGG	PTGER4	ENSG00000171522	-1.2238440683221365	[132]	[29]	-7	hSpCas9	negative selection	11405039
40681586	40681609	5	-	28162770	EOL1	viability	AAGCACGTTGCAGAGGACGGTGG	PTGER4	ENSG00000171522	-1.4677696512082257	[41]	[7]	-7	hSpCas9	negative selection	11405040
40681727	40681750	5	-	28162770	EOL1	viability	GCTGAGGCGCGGCAAGGCTGGGG	PTGER4	ENSG00000171522	0.09543233077411961	[166]	[93]	0	hSpCas9	negative selection	11405041
40681820	40681843	5	-	28162770	EOL1	viability	GATGAGCACCACCAGGGAGGTGG	PTGER4	ENSG00000171522	-0.005630778931894065	[241]	[126]	0	hSpCas9	negative selection	11405042
40681068	40681091	5	+	28162770	MOLM13	viability	GGTGATGTTCATCTTCGGGGTGG	PTGER4	ENSG00000171522	0.8193617520459564	[115]	[147]	6	hSpCas9	negative selection	11574399
40681233	40681256	5	+	28162770	MOLM13	viability	CATGAAGGGCCAATGGCCCGGGG	PTGER4	ENSG00000171522	0.5503515417365518	[135]	[143]	4	hSpCas9	negative selection	11574400
40680998	40681021	5	-	28162770	MOLM13	viability	GGACGAATTGACCCCGGGAGTGG	PTGER4	ENSG00000171522	0.9617039942075396	[195]	[275]	7	hSpCas9	negative selection	11574401
40681022	40681045	5	-	28162770	MOLM13	viability	CAGCCGGTCGGGGCTCAAGGAGG	PTGER4	ENSG00000171522	2.157549260932428	[30]	[99]	9	hSpCas9	negative selection	11574402
40681047	40681070	5	+	28162770	MOLM13	viability	CAGCCCAGTGACCATCCCGGCGG	PTGER4	ENSG00000171522	-1.1365692948023742	[148]	[48]	-5	hSpCas9	negative selection	11574403
40681143	40681166	5	+	28162770	MOLM13	viability	GGAGACGACCTTCTACACGCTGG	PTGER4	ENSG00000171522	0.8829268808234226	[152]	[203]	6	hSpCas9	negative selection	11574404
40681261	40681284	5	-	28162770	MOLM13	viability	AAGGTGCTGTACTCGCACAGCGG	PTGER4	ENSG00000171522	1.391758312328608	[106]	[202]	9	hSpCas9	negative selection	11574405
40681586	40681609	5	-	28162770	MOLM13	viability	AAGCACGTTGCAGAGGACGGTGG	PTGER4	ENSG00000171522	-0.676500527790596	[41]	[18]	-4	hSpCas9	negative selection	11574406
40681727	40681750	5	-	28162770	MOLM13	viability	GCTGAGGCGCGGCAAGGCTGGGG	PTGER4	ENSG00000171522	-0.4919215283397226	[176]	[90]	-3	hSpCas9	negative selection	11574407
40681820	40681843	5	-	28162770	MOLM13	viability	GATGAGCACCACCAGGGAGGTGG	PTGER4	ENSG00000171522	-0.9017562149202506	[291]	[112]	-5	hSpCas9	negative selection	11574408
40681068	40681091	5	+	28162770	HEL	viability	GGTGATGTTCATCTTCGGGGTGG	PTGER4	ENSG00000171522	0.162409872469794	[112]	[80]	1	hSpCas9	negative selection	11743765
40681233	40681256	5	+	28162770	HEL	viability	CATGAAGGGCCAATGGCCCGGGG	PTGER4	ENSG00000171522	1.3106627817369116	[106]	[169]	9	hSpCas9	negative selection	11743766
40680998	40681021	5	-	28162770	HEL	viability	GGACGAATTGACCCCGGGAGTGG	PTGER4	ENSG00000171522	0.6974447240904921	[206]	[214]	6	hSpCas9	negative selection	11743767
40681022	40681045	5	-	28162770	HEL	viability	CAGCCGGTCGGGGCTCAAGGAGG	PTGER4	ENSG00000171522	0.2912664614989797	[36]	[28]	2	hSpCas9	negative selection	11743768
40681047	40681070	5	+	28162770	HEL	viability	CAGCCCAGTGACCATCCCGGCGG	PTGER4	ENSG00000171522	0.5214325357782235	[123]	[113]	4	hSpCas9	negative selection	11743769
40681143	40681166	5	+	28162770	HEL	viability	GGAGACGACCTTCTACACGCTGG	PTGER4	ENSG00000171522	0.8091999781390977	[138]	[155]	7	hSpCas9	negative selection	11743770
40681261	40681284	5	-	28162770	HEL	viability	AAGGTGCTGTACTCGCACAGCGG	PTGER4	ENSG00000171522	0.36710438938692946	[114]	[94]	3	hSpCas9	negative selection	11743771
40681586	40681609	5	-	28162770	HEL	viability	AAGCACGTTGCAGAGGACGGTGG	PTGER4	ENSG00000171522	-0.4641763719161549	[27]	[12]	-3	hSpCas9	negative selection	11743772
40681727	40681750	5	-	28162770	HEL	viability	GCTGAGGCGCGGCAAGGCTGGGG	PTGER4	ENSG00000171522	-0.6496161475036583	[168]	[68]	-4	hSpCas9	negative selection	11743773
40681820	40681843	5	-	28162770	HEL	viability	GATGAGCACCACCAGGGAGGTGG	PTGER4	ENSG00000171522	0.2851868273822734	[245]	[191]	2	hSpCas9	negative selection	11743774
40681068	40681091	5	+	28162770	MV411	viability	GGTGATGTTCATCTTCGGGGTGG	PTGER4	ENSG00000171522	0.6100076301674835	[111]	[143]	5	hSpCas9	negative selection	11913131
40681233	40681256	5	+	28162770	MV411	viability	CATGAAGGGCCAATGGCCCGGGG	PTGER4	ENSG00000171522	0.6035813610080507	[99]	[127]	5	hSpCas9	negative selection	11913132
40680998	40681021	5	-	28162770	MV411	viability	GGACGAATTGACCCCGGGAGTGG	PTGER4	ENSG00000171522	-0.38483066471673755	[123]	[79]	-3	hSpCas9	negative selection	11913133
40681022	40681045	5	-	28162770	MV411	viability	CAGCCGGTCGGGGCTCAAGGAGG	PTGER4	ENSG00000171522	-0.790037154635888	[38]	[18]	-5	hSpCas9	negative selection	11913134
40681047	40681070	5	+	28162770	MV411	viability	CAGCCCAGTGACCATCCCGGCGG	PTGER4	ENSG00000171522	-0.881845466162191	[104]	[47]	-6	hSpCas9	negative selection	11913135
40681143	40681166	5	+	28162770	MV411	viability	GGAGACGACCTTCTACACGCTGG	PTGER4	ENSG00000171522	-0.16759994849606863	[83]	[62]	-1	hSpCas9	negative selection	11913136
40681261	40681284	5	-	28162770	MV411	viability	AAGGTGCTGTACTCGCACAGCGG	PTGER4	ENSG00000171522	0.8791942629828726	[90]	[140]	7	hSpCas9	negative selection	11913137
40681586	40681609	5	-	28162770	MV411	viability	AAGCACGTTGCAGAGGACGGTGG	PTGER4	ENSG00000171522	-0.8818454661621913	[34]	[15]	-6	hSpCas9	negative selection	11913138
40681727	40681750	5	-	28162770	MV411	viability	GCTGAGGCGCGGCAAGGCTGGGG	PTGER4	ENSG00000171522	-1.1580771743775617	[150]	[56]	-6	hSpCas9	negative selection	11913139
40681820	40681843	5	-	28162770	MV411	viability	GATGAGCACCACCAGGGAGGTGG	PTGER4	ENSG00000171522	0.41980159767650516	[196]	[221]	4	hSpCas9	negative selection	11913140
40681068	40681091	5	+	28162770	MONOMAC1	viability	GGTGATGTTCATCTTCGGGGTGG	PTGER4	ENSG00000171522	-0.15695940768421868	[70]	[72]	-1	hSpCas9	negative selection	12082497
40681233	40681256	5	+	28162770	MONOMAC1	viability	CATGAAGGGCCAATGGCCCGGGG	PTGER4	ENSG00000171522	0.8976000270785214	[58]	[125]	8	hSpCas9	negative selection	12082498
40680998	40681021	5	-	28162770	MONOMAC1	viability	GGACGAATTGACCCCGGGAGTGG	PTGER4	ENSG00000171522	-0.23767883155689964	[107]	[104]	-2	hSpCas9	negative selection	12082499
40681022	40681045	5	-	28162770	MONOMAC1	viability	CAGCCGGTCGGGGCTCAAGGAGG	PTGER4	ENSG00000171522	0.5034028710815384	[7]	[12]	5	hSpCas9	negative selection	12082500
40681047	40681070	5	+	28162770	MONOMAC1	viability	CAGCCCAGTGACCATCCCGGCGG	PTGER4	ENSG00000171522	0.2757161500755776	[48]	[67]	2	hSpCas9	negative selection	12082501
40681143	40681166	5	+	28162770	MONOMAC1	viability	GGAGACGACCTTCTACACGCTGG	PTGER4	ENSG00000171522	0.17219696260616524	[47]	[61]	1	hSpCas9	negative selection	12082502
40681261	40681284	5	-	28162770	MONOMAC1	viability	AAGGTGCTGTACTCGCACAGCGG	PTGER4	ENSG00000171522	0.005780035940133432	[52]	[60]	0	hSpCas9	negative selection	12082503
40681586	40681609	5	-	28162770	MONOMAC1	viability	AAGCACGTTGCAGAGGACGGTGG	PTGER4	ENSG00000171522	1.2504221299116676	[10]	[29]	9	hSpCas9	negative selection	12082504
40681727	40681750	5	-	28162770	MONOMAC1	viability	GCTGAGGCGCGGCAAGGCTGGGG	PTGER4	ENSG00000171522	-0.2508081035005343	[81]	[78]	-2	hSpCas9	negative selection	12082505
40681820	40681843	5	-	28162770	MONOMAC1	viability	GATGAGCACCACCAGGGAGGTGG	PTGER4	ENSG00000171522	0.06599755877424025	[129]	[155]	0	hSpCas9	negative selection	12082506
40681068	40681091	5	+	28162770	OCIAML2	viability	GGTGATGTTCATCTTCGGGGTGG	PTGER4	ENSG00000171522	1.008341979790781	[19]	[222]	8	hSpCas9	negative selection	12251863
40681233	40681256	5	+	28162770	OCIAML2	viability	CATGAAGGGCCAATGGCCCGGGG	PTGER4	ENSG00000171522	-0.35515260782222524	[20]	[90]	-3	hSpCas9	negative selection	12251864
40680998	40681021	5	-	28162770	OCIAML2	viability	GGACGAATTGACCCCGGGAGTGG	PTGER4	ENSG00000171522	0.818131405710002	[21]	[214]	7	hSpCas9	negative selection	12251865
40681022	40681045	5	-	28162770	OCIAML2	viability	CAGCCGGTCGGGGCTCAAGGAGG	PTGER4	ENSG00000171522	1.0147970019280805	[4]	[55]	8	hSpCas9	negative selection	12251866
40681047	40681070	5	+	28162770	OCIAML2	viability	CAGCCCAGTGACCATCCCGGCGG	PTGER4	ENSG00000171522	-0.035243680571514835	[21]	[118]	0	hSpCas9	negative selection	12251867
40681143	40681166	5	+	28162770	OCIAML2	viability	GGAGACGACCTTCTACACGCTGG	PTGER4	ENSG00000171522	1.3537986101743844	[17]	[254]	9	hSpCas9	negative selection	12251868
40681261	40681284	5	-	28162770	OCIAML2	viability	AAGGTGCTGTACTCGCACAGCGG	PTGER4	ENSG00000171522	0.861566605099028	[13]	[140]	8	hSpCas9	negative selection	12251869
40681586	40681609	5	-	28162770	OCIAML2	viability	AAGCACGTTGCAGAGGACGGTGG	PTGER4	ENSG00000171522	-1.2482374039057134	[5]	[13]	-7	hSpCas9	negative selection	12251870
40681727	40681750	5	-	28162770	OCIAML2	viability	GCTGAGGCGCGGCAAGGCTGGGG	PTGER4	ENSG00000171522	-0.11073388015577837	[29]	[153]	-1	hSpCas9	negative selection	12251871
40681820	40681843	5	-	28162770	OCIAML2	viability	GATGAGCACCACCAGGGAGGTGG	PTGER4	ENSG00000171522	-2.04532399050949	[34]	[46]	-8	hSpCas9	negative selection	12251872
40681068	40681091	5	+	28162770	OCIAML3	viability	GGTGATGTTCATCTTCGGGGTGG	PTGER4	ENSG00000171522	-0.025723880749637384	[28]	[85]	0	hSpCas9	negative selection	12421229
40681233	40681256	5	+	28162770	OCIAML3	viability	CATGAAGGGCCAATGGCCCGGGG	PTGER4	ENSG00000171522	0.7188753149601923	[31]	[158]	6	hSpCas9	negative selection	12421230
40680998	40681021	5	-	28162770	OCIAML3	viability	GGACGAATTGACCCCGGGAGTGG	PTGER4	ENSG00000171522	1.2369341020510567	[51]	[369]	8	hSpCas9	negative selection	12421231
40681022	40681045	5	-	28162770	OCIAML3	viability	CAGCCGGTCGGGGCTCAAGGAGG	PTGER4	ENSG00000171522	-0.700922844240675	[6]	[12]	-5	hSpCas9	negative selection	12421232
40681047	40681070	5	+	28162770	OCIAML3	viability	CAGCCCAGTGACCATCCCGGCGG	PTGER4	ENSG00000171522	-0.3183731977107358	[18]	[45]	-2	hSpCas9	negative selection	12421233
40681143	40681166	5	+	28162770	OCIAML3	viability	GGAGACGACCTTCTACACGCTGG	PTGER4	ENSG00000171522	-1.009045139603007	[25]	[38]	-6	hSpCas9	negative selection	12421234
40681261	40681284	5	-	28162770	OCIAML3	viability	AAGGTGCTGTACTCGCACAGCGG	PTGER4	ENSG00000171522	-0.6167277168242467	[31]	[62]	-5	hSpCas9	negative selection	12421235
40681586	40681609	5	-	28162770	OCIAML3	viability	AAGCACGTTGCAGAGGACGGTGG	PTGER4	ENSG00000171522	1.0840642647884744	[4]	[31]	8	hSpCas9	negative selection	12421236
40681727	40681750	5	-	28162770	OCIAML3	viability	GCTGAGGCGCGGCAAGGCTGGGG	PTGER4	ENSG00000171522	-0.3969707932646095	[40]	[93]	-3	hSpCas9	negative selection	12421237
40681820	40681843	5	-	28162770	OCIAML3	viability	GATGAGCACCACCAGGGAGGTGG	PTGER4	ENSG00000171522	-0.1474919095721513	[50]	[138]	-1	hSpCas9	negative selection	12421238