Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:5739
• Symbol:PTGIR
• Description:prostaglandin I2 receptor

DataSource: http://genomecrispr.dkfz.de/#!/results/PTGIR

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
46623838	46623861	19	+	26472758	Jiyoye	viability	GCTGCGCGTAGAGGTAGGGGTGG	PTGIR	ENSG00000160013	-1.3973534964729675	[254]	[72]	-7	hSpCas9	negative selection	130738
46624031	46624054	19	+	26472758	Jiyoye	viability	GCTGGTGCCCAGCAGGTCGGTGG	PTGIR	ENSG00000160013	-0.25178770065905975	[89]	[56]	-2	hSpCas9	negative selection	130739
46623709	46623732	19	+	26472758	Jiyoye	viability	GGAGGAAGCACCAGCTGCCGGGG	PTGIR	ENSG00000160013	-0.7252749145177764	[113]	[51]	-5	hSpCas9	negative selection	130740
46624061	46624084	19	+	26472758	Jiyoye	viability	TCCGGTCACCAGCACCGCGAAGG	PTGIR	ENSG00000160013	1.4353722733365253	[75]	[154]	8	hSpCas9	negative selection	130741
46623923	46623946	19	+	26472758	Jiyoye	viability	GAAGGTCATGGCGAAGGCGAAGG	PTGIR	ENSG00000160013	0.7067356633647811	[77]	[95]	5	hSpCas9	negative selection	130742
46623604	46623627	19	+	26472758	Jiyoye	viability	GGGTGACCGAGCCGTTGCAGAGG	PTGIR	ENSG00000160013	-0.6708271304953998	[75]	[35]	-5	hSpCas9	negative selection	130743
46623577	46623600	19	+	26472758	Jiyoye	viability	GCTGGCGGTACATGCGGCAGAGG	PTGIR	ENSG00000160013	-1.0869336887641692	[399]	[141]	-6	hSpCas9	negative selection	130744
46623544	46623567	19	+	26472758	Jiyoye	viability	GCCGTGGACCCAGAGAGCCCTGG	PTGIR	ENSG00000160013	-3.6372187378525798	[98]	[5]	-9	hSpCas9	negative selection	130745
46623520	46623543	19	-	26472758	Jiyoye	viability	GCGCACCGGAGAGGACGAGGTGG	PTGIR	ENSG00000160013	-2.1163865745511394	[22]	[3]	-8	hSpCas9	negative selection	130746
46624190	46624213	19	-	26472758	Jiyoye	viability	GCAGGAACCTCACCTACGTGCGG	PTGIR	ENSG00000160013	-0.35689544282293056	[196]	[115]	-3	hSpCas9	negative selection	130747
46623838	46623861	19	+	26472758	KBM7	viability	GCTGCGCGTAGAGGTAGGGGTGG	PTGIR	ENSG00000160013	0.2835277209717611	[458,671]	[341,321]	3	hSpCas9	negative selection	321856
46624031	46624054	19	+	26472758	KBM7	viability	GCTGGTGCCCAGCAGGTCGGTGG	PTGIR	ENSG00000160013	-0.40150704666133663	[314,289]	[36,170]	-4	hSpCas9	negative selection	321857
46623709	46623732	19	+	26472758	KBM7	viability	GGAGGAAGCACCAGCTGCCGGGG	PTGIR	ENSG00000160013	-1.6103677655830895	[469,205]	[45,53]	-8	hSpCas9	negative selection	321858
46624061	46624084	19	+	26472758	KBM7	viability	TCCGGTCACCAGCACCGCGAAGG	PTGIR	ENSG00000160013	0.4068025211197497	[813,557]	[401,438]	4	hSpCas9	negative selection	321859
46623923	46623946	19	+	26472758	KBM7	viability	GAAGGTCATGGCGAAGGCGAAGG	PTGIR	ENSG00000160013	0.15309010616411167	[629,383]	[244,272]	1	hSpCas9	negative selection	321860
46623604	46623627	19	+	26472758	KBM7	viability	GGGTGACCGAGCCGTTGCAGAGG	PTGIR	ENSG00000160013	-0.5251116676599483	[171,97]	[31,52]	-4	hSpCas9	negative selection	321861
46623577	46623600	19	+	26472758	KBM7	viability	GCTGGCGGTACATGCGGCAGAGG	PTGIR	ENSG00000160013	0.4471175594318896	[953,833]	[648,502]	5	hSpCas9	negative selection	321862
46623544	46623567	19	+	26472758	KBM7	viability	GCCGTGGACCCAGAGAGCCCTGG	PTGIR	ENSG00000160013	-1.4173860444977053	[243,227]	[67,17]	-7	hSpCas9	negative selection	321863
46623520	46623543	19	-	26472758	KBM7	viability	GCGCACCGGAGAGGACGAGGTGG	PTGIR	ENSG00000160013	-2.3608953828504617	[46,27]	[5,0]	-9	hSpCas9	negative selection	321864
46624190	46624213	19	-	26472758	KBM7	viability	GCAGGAACCTCACCTACGTGCGG	PTGIR	ENSG00000160013	0.029961652989876963	[924,1019]	[443,495]	0	hSpCas9	negative selection	321865
46623838	46623861	19	+	26472758	Raji	viability	GCTGCGCGTAGAGGTAGGGGTGG	PTGIR	ENSG00000160013	0.397462764221622	[228]	[69]	4	hSpCas9	negative selection	512974
46624031	46624054	19	+	26472758	Raji	viability	GCTGGTGCCCAGCAGGTCGGTGG	PTGIR	ENSG00000160013	0.1948463766239389	[191]	[50]	1	hSpCas9	negative selection	512975
46623709	46623732	19	+	26472758	Raji	viability	GGAGGAAGCACCAGCTGCCGGGG	PTGIR	ENSG00000160013	-1.3683498955927984	[177]	[15]	-7	hSpCas9	negative selection	512976
46624061	46624084	19	+	26472758	Raji	viability	TCCGGTCACCAGCACCGCGAAGG	PTGIR	ENSG00000160013	-0.5433810237433029	[313]	[49]	-4	hSpCas9	negative selection	512977
46623923	46623946	19	+	26472758	Raji	viability	GAAGGTCATGGCGAAGGCGAAGG	PTGIR	ENSG00000160013	0.8681958714941734	[143]	[60]	7	hSpCas9	negative selection	512978
46623604	46623627	19	+	26472758	Raji	viability	GGGTGACCGAGCCGTTGCAGAGG	PTGIR	ENSG00000160013	0.352496033210131	[80]	[23]	3	hSpCas9	negative selection	512979
46623577	46623600	19	+	26472758	Raji	viability	GCTGGCGGTACATGCGGCAGAGG	PTGIR	ENSG00000160013	-0.2718777345797143	[384]	[73]	-2	hSpCas9	negative selection	512980
46623544	46623567	19	+	26472758	Raji	viability	GCCGTGGACCCAGAGAGCCCTGG	PTGIR	ENSG00000160013	-2.8074998509884495	[180]	[5]	-9	hSpCas9	negative selection	512981
46623520	46623543	19	-	26472758	Raji	viability	GCGCACCGGAGAGGACGAGGTGG	PTGIR	ENSG00000160013	0.6668109439876178	[18]	[6]	6	hSpCas9	negative selection	512982
46624190	46624213	19	-	26472758	Raji	viability	GCAGGAACCTCACCTACGTGCGG	PTGIR	ENSG00000160013	-0.15507275182256863	[498]	[103]	-1	hSpCas9	negative selection	512983
46623838	46623861	19	+	26472758	K562	viability	GCTGCGCGTAGAGGTAGGGGTGG	PTGIR	ENSG00000160013	0.4877369878574429	[527]	[624]	4	hSpCas9	negative selection	704092
46624031	46624054	19	+	26472758	K562	viability	GCTGGTGCCCAGCAGGTCGGTGG	PTGIR	ENSG00000160013	0.18569628854374454	[350]	[336]	1	hSpCas9	negative selection	704093
46623709	46623732	19	+	26472758	K562	viability	GGAGGAAGCACCAGCTGCCGGGG	PTGIR	ENSG00000160013	-0.8409727635641977	[173]	[81]	-5	hSpCas9	negative selection	704094
46624061	46624084	19	+	26472758	K562	viability	TCCGGTCACCAGCACCGCGAAGG	PTGIR	ENSG00000160013	-0.6914509349138375	[571]	[298]	-4	hSpCas9	negative selection	704095
46623923	46623946	19	+	26472758	K562	viability	GAAGGTCATGGCGAAGGCGAAGG	PTGIR	ENSG00000160013	0.17909247978850348	[383]	[366]	1	hSpCas9	negative selection	704096
46623604	46623627	19	+	26472758	K562	viability	GGGTGACCGAGCCGTTGCAGAGG	PTGIR	ENSG00000160013	-0.8826931902368922	[82]	[37]	-5	hSpCas9	negative selection	704097
46623577	46623600	19	+	26472758	K562	viability	GCTGGCGGTACATGCGGCAGAGG	PTGIR	ENSG00000160013	-0.2698500470102908	[676]	[473]	-2	hSpCas9	negative selection	704098
46623544	46623567	19	+	26472758	K562	viability	GCCGTGGACCCAGAGAGCCCTGG	PTGIR	ENSG00000160013	-3.6431065430751404	[221]	[14]	-9	hSpCas9	negative selection	704099
46623520	46623543	19	-	26472758	K562	viability	GCGCACCGGAGAGGACGAGGTGG	PTGIR	ENSG00000160013	1.5074531335002406	[9]	[23]	9	hSpCas9	negative selection	704100
46624190	46624213	19	-	26472758	K562	viability	GCAGGAACCTCACCTACGTGCGG	PTGIR	ENSG00000160013	0.27637549443810816	[758]	[775]	2	hSpCas9	negative selection	704101
46621344	46621367	19	+	26627737	DLD1	viability	GACTGCTGTGTGGGAGGCAAGGG	PTGIR	ENSG00000160013	-1.0614710115541146	[523]	[107,52,73]	-7	hSpCas9	negative selection	805630
46621410	46621433	19	-	26627737	DLD1	viability	TCTGCTCCTGTGGGAAAGGAGGG	PTGIR	ENSG00000160013	-0.11821734173891407	[251]	[61,93,63]	-1	hSpCas9	negative selection	805631
46623770	46623793	19	+	26627737	DLD1	viability	CGCGCAGAAGAGGACGCAGAAGG	PTGIR	ENSG00000160013	-0.013316458229103989	[692]	[218,205,217]	0	hSpCas9	negative selection	805632
46623934	46623957	19	+	26627737	DLD1	viability	CGAAGGCGAAGGCATCGCACAGG	PTGIR	ENSG00000160013	-0.8314428561480381	[760]	[74,207,122]	-7	hSpCas9	negative selection	805633
46623940	46623963	19	+	26627737	DLD1	viability	CGAAGGCATCGCACAGGGCGGGG	PTGIR	ENSG00000160013	0.5118422980358261	[736]	[180,474,334]	5	hSpCas9	negative selection	805634
46623995	46624018	19	+	26627737	DLD1	viability	GCGCGCATAGGCCACGAACACGG	PTGIR	ENSG00000160013	-0.10917342319691659	[1900]	[551,469,616]	-1	hSpCas9	negative selection	805635
46621344	46621367	19	+	26627737	GBM cells	viability after 5 days	GACTGCTGTGTGGGAGGCAAGGG	PTGIR	ENSG00000160013	0.15751603440421869	[162]	[93,100]	2	hSpCas9	negative selection	887945
46621410	46621433	19	-	26627737	GBM cells	viability after 5 days	TCTGCTCCTGTGGGAAAGGAGGG	PTGIR	ENSG00000160013	-0.7105016695600097	[237]	[59,95]	-8	hSpCas9	negative selection	887946
46623770	46623793	19	+	26627737	GBM cells	viability after 5 days	CGCGCAGAAGAGGACGCAGAAGG	PTGIR	ENSG00000160013	-0.37544853674962086	[357]	[148,146]	-5	hSpCas9	negative selection	887947
46623934	46623957	19	+	26627737	GBM cells	viability after 5 days	CGAAGGCGAAGGCATCGCACAGG	PTGIR	ENSG00000160013	0.6734937608516696	[158]	[151,119]	8	hSpCas9	negative selection	887948
46623940	46623963	19	+	26627737	GBM cells	viability after 5 days	CGAAGGCATCGCACAGGGCGGGG	PTGIR	ENSG00000160013	-0.2728111206028369	[400]	[146,208]	-4	hSpCas9	negative selection	887949
46623995	46624018	19	+	26627737	GBM cells	viability after 5 days	GCGCGCATAGGCCACGAACACGG	PTGIR	ENSG00000160013	0.10379147516242271	[733]	[469,375]	1	hSpCas9	negative selection	887950
46621344	46621367	19	+	26627737	GBM cells	viability after 13 days	GACTGCTGTGTGGGAGGCAAGGG	PTGIR	ENSG00000160013	0.7827673249745162	[162]	[187,122]	8	hSpCas9	negative selection	970260
46621410	46621433	19	-	26627737	GBM cells	viability after 13 days	TCTGCTCCTGTGGGAAAGGAGGG	PTGIR	ENSG00000160013	-0.6501261437057891	[237]	[105,62]	-6	hSpCas9	negative selection	970261
46623770	46623793	19	+	26627737	GBM cells	viability after 13 days	CGCGCAGAAGAGGACGCAGAAGG	PTGIR	ENSG00000160013	0.1136942306475286	[357]	[277,154]	1	hSpCas9	negative selection	970262
46623934	46623957	19	+	26627737	GBM cells	viability after 13 days	CGAAGGCGAAGGCATCGCACAGG	PTGIR	ENSG00000160013	-0.17366935036004705	[158]	[81,71]	-2	hSpCas9	negative selection	970263
46623940	46623963	19	+	26627737	GBM cells	viability after 13 days	CGAAGGCATCGCACAGGGCGGGG	PTGIR	ENSG00000160013	-0.14158137633302792	[400]	[183,207]	-2	hSpCas9	negative selection	970264
46623995	46624018	19	+	26627737	GBM cells	viability after 13 days	GCGCGCATAGGCCACGAACACGG	PTGIR	ENSG00000160013	0.2842421895024043	[733]	[586,401]	3	hSpCas9	negative selection	970265
46621344	46621367	19	+	26627737	GBM cells	viability after 21 days	GACTGCTGTGTGGGAGGCAAGGG	PTGIR	ENSG00000160013	0.780697626064744	[162]	[148,154]	7	hSpCas9	negative selection	1052575
46621410	46621433	19	-	26627737	GBM cells	viability after 21 days	TCTGCTCCTGTGGGAAAGGAGGG	PTGIR	ENSG00000160013	-0.7943405089344141	[237]	[84,64]	-6	hSpCas9	negative selection	1052576
46623770	46623793	19	+	26627737	GBM cells	viability after 21 days	CGCGCAGAAGAGGACGCAGAAGG	PTGIR	ENSG00000160013	-0.2982807013486448	[357]	[165,150]	-3	hSpCas9	negative selection	1052577
46623934	46623957	19	+	26627737	GBM cells	viability after 21 days	CGAAGGCGAAGGCATCGCACAGG	PTGIR	ENSG00000160013	0.2519820952935195	[158]	[105,99]	2	hSpCas9	negative selection	1052578
46623940	46623963	19	+	26627737	GBM cells	viability after 21 days	CGAAGGCATCGCACAGGGCGGGG	PTGIR	ENSG00000160013	-0.16946222894083196	[400]	[176,208]	-1	hSpCas9	negative selection	1052579
46623995	46624018	19	+	26627737	GBM cells	viability after 21 days	GCGCGCATAGGCCACGAACACGG	PTGIR	ENSG00000160013	-0.17202383256366538	[733]	[366,341]	-1	hSpCas9	negative selection	1052580
46621344	46621367	19	+	26627737	RPE1	viability after 9 days	GACTGCTGTGTGGGAGGCAAGGG	PTGIR	ENSG00000160013	-0.1705198410127594	[1247]	[330,367]	-1	hSpCas9	negative selection	1134890
46621410	46621433	19	-	26627737	RPE1	viability after 9 days	TCTGCTCCTGTGGGAAAGGAGGG	PTGIR	ENSG00000160013	-0.39473799868067366	[1130]	[274,261]	-3	hSpCas9	negative selection	1134891
46623770	46623793	19	+	26627737	RPE1	viability after 9 days	CGCGCAGAAGAGGACGCAGAAGG	PTGIR	ENSG00000160013	-0.6156085982871622	[1468]	[190,440]	-4	hSpCas9	negative selection	1134892
46623934	46623957	19	+	26627737	RPE1	viability after 9 days	CGAAGGCGAAGGCATCGCACAGG	PTGIR	ENSG00000160013	0.8904709219413016	[597]	[467,190]	6	hSpCas9	negative selection	1134893
46623940	46623963	19	+	26627737	RPE1	viability after 9 days	CGAAGGCATCGCACAGGGCGGGG	PTGIR	ENSG00000160013	2.0960859096865017	[428]	[685,429]	9	hSpCas9	negative selection	1134894
46623995	46624018	19	+	26627737	RPE1	viability after 9 days	GCGCGCATAGGCCACGAACACGG	PTGIR	ENSG00000160013	0.23280096829353059	[2974]	[773,1507]	1	hSpCas9	negative selection	1134895
46621344	46621367	19	+	26627737	RPE1	viability after 12 days	GACTGCTGTGTGGGAGGCAAGGG	PTGIR	ENSG00000160013	-0.4513075410897377	[1247]	[303,182]	-3	hSpCas9	negative selection	1217205
46621410	46621433	19	-	26627737	RPE1	viability after 12 days	TCTGCTCCTGTGGGAAAGGAGGG	PTGIR	ENSG00000160013	-0.21778736462557036	[1130]	[287,232]	-1	hSpCas9	negative selection	1217206
46623770	46623793	19	+	26627737	RPE1	viability after 12 days	CGCGCAGAAGAGGACGCAGAAGG	PTGIR	ENSG00000160013	-0.7193351905009229	[1468]	[229,249]	-5	hSpCas9	negative selection	1217207
46623934	46623957	19	+	26627737	RPE1	viability after 12 days	CGAAGGCGAAGGCATCGCACAGG	PTGIR	ENSG00000160013	0.7978552903487959	[597]	[255,303]	5	hSpCas9	negative selection	1217208
46623940	46623963	19	+	26627737	RPE1	viability after 12 days	CGAAGGCATCGCACAGGGCGGGG	PTGIR	ENSG00000160013	2.08446237531949	[428]	[618,350]	9	hSpCas9	negative selection	1217209
46623995	46624018	19	+	26627737	RPE1	viability after 12 days	GCGCGCATAGGCCACGAACACGG	PTGIR	ENSG00000160013	0.41054879505003217	[2974]	[803,1335]	2	hSpCas9	negative selection	1217210
46621344	46621367	19	+	26627737	RPE1	viability after 15 days	GACTGCTGTGTGGGAGGCAAGGG	PTGIR	ENSG00000160013	-0.33921619522633545	[1247]	[359,200]	-2	hSpCas9	negative selection	1299520
46621410	46621433	19	-	26627737	RPE1	viability after 15 days	TCTGCTCCTGTGGGAAAGGAGGG	PTGIR	ENSG00000160013	-0.5723488386033899	[1130]	[205,223]	-4	hSpCas9	negative selection	1299521
46623770	46623793	19	+	26627737	RPE1	viability after 15 days	CGCGCAGAAGAGGACGCAGAAGG	PTGIR	ENSG00000160013	-0.5969357161551099	[1468]	[232,314]	-4	hSpCas9	negative selection	1299522
46623934	46623957	19	+	26627737	RPE1	viability after 15 days	CGAAGGCGAAGGCATCGCACAGG	PTGIR	ENSG00000160013	0.7865989327368764	[597]	[330,253]	5	hSpCas9	negative selection	1299523
46623940	46623963	19	+	26627737	RPE1	viability after 15 days	CGAAGGCATCGCACAGGGCGGGG	PTGIR	ENSG00000160013	1.7159733134949784	[428]	[613,190]	8	hSpCas9	negative selection	1299524
46623995	46624018	19	+	26627737	RPE1	viability after 15 days	GCGCGCATAGGCCACGAACACGG	PTGIR	ENSG00000160013	0.34719888316374425	[2974]	[786,1343]	2	hSpCas9	negative selection	1299525
46621344	46621367	19	+	26627737	RPE1	viability after 18 days	GACTGCTGTGTGGGAGGCAAGGG	PTGIR	ENSG00000160013	-0.4574782732362492	[1247]	[296,189]	-3	hSpCas9	negative selection	1381835
46621410	46621433	19	-	26627737	RPE1	viability after 18 days	TCTGCTCCTGTGGGAAAGGAGGG	PTGIR	ENSG00000160013	-0.194274375124302	[1130]	[259,273]	-1	hSpCas9	negative selection	1381836
46623770	46623793	19	+	26627737	RPE1	viability after 18 days	CGCGCAGAAGAGGACGCAGAAGG	PTGIR	ENSG00000160013	-0.5329183374950106	[1468]	[171,382]	-3	hSpCas9	negative selection	1381837
46623934	46623957	19	+	26627737	RPE1	viability after 18 days	CGAAGGCGAAGGCATCGCACAGG	PTGIR	ENSG00000160013	0.9334295699789006	[597]	[357,254]	5	hSpCas9	negative selection	1381838
46623940	46623963	19	+	26627737	RPE1	viability after 18 days	CGAAGGCATCGCACAGGGCGGGG	PTGIR	ENSG00000160013	1.7015856227999158	[428]	[494,249]	8	hSpCas9	negative selection	1381839
46623995	46624018	19	+	26627737	RPE1	viability after 18 days	GCGCGCATAGGCCACGAACACGG	PTGIR	ENSG00000160013	0.1008478518251581	[2974]	[714,1016]	0	hSpCas9	negative selection	1381840
46621344	46621367	19	+	26627737	HeLa	viability after 8 days	GACTGCTGTGTGGGAGGCAAGGG	PTGIR	ENSG00000160013	0.3438457494480145	[273]	[156,143,153]	3	hSpCas9	negative selection	1464150
46621410	46621433	19	-	26627737	HeLa	viability after 8 days	TCTGCTCCTGTGGGAAAGGAGGG	PTGIR	ENSG00000160013	-0.13487418375851123	[391]	[143,244,79]	-1	hSpCas9	negative selection	1464151
46623770	46623793	19	+	26627737	HeLa	viability after 8 days	CGCGCAGAAGAGGACGCAGAAGG	PTGIR	ENSG00000160013	0.5321330870439858	[482]	[227,154,497]	5	hSpCas9	negative selection	1464152
46623934	46623957	19	+	26627737	HeLa	viability after 8 days	CGAAGGCGAAGGCATCGCACAGG	PTGIR	ENSG00000160013	-0.9716147111741344	[530]	[246,62,74]	-7	hSpCas9	negative selection	1464153
46623940	46623963	19	+	26627737	HeLa	viability after 8 days	CGAAGGCATCGCACAGGGCGGGG	PTGIR	ENSG00000160013	1.9636953426058033	[256]	[321,384,566]	9	hSpCas9	negative selection	1464154
46623995	46624018	19	+	26627737	HeLa	viability after 8 days	GCGCGCATAGGCCACGAACACGG	PTGIR	ENSG00000160013	0.027781475374812015	[1739]	[776,890,656]	0	hSpCas9	negative selection	1464155
46621344	46621367	19	+	26627737	HeLa	viability after 12 days	GACTGCTGTGTGGGAGGCAAGGG	PTGIR	ENSG00000160013	-0.597268399775261	[273]	[8,127,79]	-5	hSpCas9	negative selection	1546465
46621410	46621433	19	-	26627737	HeLa	viability after 12 days	TCTGCTCCTGTGGGAAAGGAGGG	PTGIR	ENSG00000160013	0.20388130201132093	[391]	[207,161,192]	1	hSpCas9	negative selection	1546466
46623770	46623793	19	+	26627737	HeLa	viability after 12 days	CGCGCAGAAGAGGACGCAGAAGG	PTGIR	ENSG00000160013	0.9265225830714531	[482]	[658,268,229]	7	hSpCas9	negative selection	1546467
46623934	46623957	19	+	26627737	HeLa	viability after 12 days	CGAAGGCGAAGGCATCGCACAGG	PTGIR	ENSG00000160013	-0.8713238560814016	[530]	[110,87,163]	-7	hSpCas9	negative selection	1546468
46623940	46623963	19	+	26627737	HeLa	viability after 12 days	CGAAGGCATCGCACAGGGCGGGG	PTGIR	ENSG00000160013	1.7218913248392638	[256]	[133,517,374]	9	hSpCas9	negative selection	1546469
46623995	46624018	19	+	26627737	HeLa	viability after 12 days	GCGCGCATAGGCCACGAACACGG	PTGIR	ENSG00000160013	0.09764074768211684	[1739]	[725,816,758]	0	hSpCas9	negative selection	1546470
46621344	46621367	19	+	26627737	HeLa	viability after 15 days	GACTGCTGTGTGGGAGGCAAGGG	PTGIR	ENSG00000160013	-0.12881499134662644	[273]	[112,113,76]	-1	hSpCas9	negative selection	1628780
46621410	46621433	19	-	26627737	HeLa	viability after 15 days	TCTGCTCCTGTGGGAAAGGAGGG	PTGIR	ENSG00000160013	-0.3377903532546641	[391]	[128,144,102]	-3	hSpCas9	negative selection	1628781
46623770	46623793	19	+	26627737	HeLa	viability after 15 days	CGCGCAGAAGAGGACGCAGAAGG	PTGIR	ENSG00000160013	0.28319376444675115	[482]	[292,258,158]	2	hSpCas9	negative selection	1628782
46623934	46623957	19	+	26627737	HeLa	viability after 15 days	CGAAGGCGAAGGCATCGCACAGG	PTGIR	ENSG00000160013	-0.6966395398522784	[530]	[47,101,260]	-6	hSpCas9	negative selection	1628783
46623940	46623963	19	+	26627737	HeLa	viability after 15 days	CGAAGGCATCGCACAGGGCGGGG	PTGIR	ENSG00000160013	2.532682994440324	[256]	[624,524,670]	9	hSpCas9	negative selection	1628784
46623995	46624018	19	+	26627737	HeLa	viability after 15 days	GCGCGCATAGGCCACGAACACGG	PTGIR	ENSG00000160013	-0.2923278620707346	[1739]	[474,702,556]	-3	hSpCas9	negative selection	1628785
46621344	46621367	19	+	26627737	HeLa	viability after 18 days	GACTGCTGTGTGGGAGGCAAGGG	PTGIR	ENSG00000160013	-0.0755412468847666	[273]	[81,95,76]	0	hSpCas9	negative selection	1711095
46621410	46621433	19	-	26627737	HeLa	viability after 18 days	TCTGCTCCTGTGGGAAAGGAGGG	PTGIR	ENSG00000160013	-0.3508051549114101	[391]	[81,122,102]	-3	hSpCas9	negative selection	1711096
46623770	46623793	19	+	26627737	HeLa	viability after 18 days	CGCGCAGAAGAGGACGCAGAAGG	PTGIR	ENSG00000160013	0.22899625645128652	[482]	[186,204,158]	2	hSpCas9	negative selection	1711097
46623934	46623957	19	+	26627737	HeLa	viability after 18 days	CGAAGGCGAAGGCATCGCACAGG	PTGIR	ENSG00000160013	-0.6656856602455923	[530]	[34,87,260]	-5	hSpCas9	negative selection	1711098
46623940	46623963	19	+	26627737	HeLa	viability after 18 days	CGAAGGCATCGCACAGGGCGGGG	PTGIR	ENSG00000160013	2.5401056535435367	[256]	[433,423,670]	9	hSpCas9	negative selection	1711099
46623995	46624018	19	+	26627737	HeLa	viability after 18 days	GCGCGCATAGGCCACGAACACGG	PTGIR	ENSG00000160013	-0.3166260077392804	[1739]	[307,571,556]	-3	hSpCas9	negative selection	1711100
46621344	46621367	19	+	26627737	HCT116	viability after 6 days	GACTGCTGTGTGGGAGGCAAGGG	PTGIR	ENSG00000160013	0.5107798394229384	[506]	[197,66]	3	hSpCas9	negative selection	1793410
46621410	46621433	19	-	26627737	HCT116	viability after 6 days	TCTGCTCCTGTGGGAAAGGAGGG	PTGIR	ENSG00000160013	-1.774574032072237	[619]	[32,25]	-7	hSpCas9	negative selection	1793411
46623770	46623793	19	+	26627737	HCT116	viability after 6 days	CGCGCAGAAGAGGACGCAGAAGG	PTGIR	ENSG00000160013	-1.500204266328653	[1736]	[247,12]	-7	hSpCas9	negative selection	1793412
46623934	46623957	19	+	26627737	HCT116	viability after 6 days	CGAAGGCGAAGGCATCGCACAGG	PTGIR	ENSG00000160013	1.3710364228914733	[663]	[405,194]	7	hSpCas9	negative selection	1793413
46623940	46623963	19	+	26627737	HCT116	viability after 6 days	CGAAGGCATCGCACAGGGCGGGG	PTGIR	ENSG00000160013	2.2506504007038424	[671]	[514,495]	9	hSpCas9	negative selection	1793414
46623995	46624018	19	+	26627737	HCT116	viability after 6 days	GCGCGCATAGGCCACGAACACGG	PTGIR	ENSG00000160013	0.0024660473228661495	[1753]	[466,170]	0	hSpCas9	negative selection	1793415
46621344	46621367	19	+	26627737	HCT116	viability after 8 days	GACTGCTGTGTGGGAGGCAAGGG	PTGIR	ENSG00000160013	0.8269442477264277	[119]	[174,66,110]	7	hSpCas9	negative selection	1875725
46621410	46621433	19	-	26627737	HCT116	viability after 8 days	TCTGCTCCTGTGGGAAAGGAGGG	PTGIR	ENSG00000160013	0.866546260786946	[177]	[197,172,165]	7	hSpCas9	negative selection	1875726
46623770	46623793	19	+	26627737	HCT116	viability after 8 days	CGCGCAGAAGAGGACGCAGAAGG	PTGIR	ENSG00000160013	0.05284912412473963	[508]	[305,186,378]	0	hSpCas9	negative selection	1875727
46623934	46623957	19	+	26627737	HCT116	viability after 8 days	CGAAGGCGAAGGCATCGCACAGG	PTGIR	ENSG00000160013	-1.209268020020571	[471]	[99,105,130]	-9	hSpCas9	negative selection	1875728
46623940	46623963	19	+	26627737	HCT116	viability after 8 days	CGAAGGCATCGCACAGGGCGGGG	PTGIR	ENSG00000160013	-0.19846214136028517	[549]	[283,186,320]	-2	hSpCas9	negative selection	1875729
46623995	46624018	19	+	26627737	HCT116	viability after 8 days	GCGCGCATAGGCCACGAACACGG	PTGIR	ENSG00000160013	0.4986086499822864	[929]	[683,651,833]	5	hSpCas9	negative selection	1875730
46621344	46621367	19	+	26627737	HCT116	viability after 9 days	GACTGCTGTGTGGGAGGCAAGGG	PTGIR	ENSG00000160013	-0.08624386320686833	[506]	[174,89]	0	hSpCas9	negative selection	1958040
46621410	46621433	19	-	26627737	HCT116	viability after 9 days	TCTGCTCCTGTGGGAAAGGAGGG	PTGIR	ENSG00000160013	-1.9011078600442726	[619]	[45,42]	-8	hSpCas9	negative selection	1958041
46623770	46623793	19	+	26627737	HCT116	viability after 9 days	CGCGCAGAAGAGGACGCAGAAGG	PTGIR	ENSG00000160013	-1.0979988340895792	[1736]	[276,168]	-6	hSpCas9	negative selection	1958042
46623934	46623957	19	+	26627737	HCT116	viability after 9 days	CGAAGGCGAAGGCATCGCACAGG	PTGIR	ENSG00000160013	-0.2479183278092893	[663]	[236,79]	-2	hSpCas9	negative selection	1958043
46623940	46623963	19	+	26627737	HCT116	viability after 9 days	CGAAGGCATCGCACAGGGCGGGG	PTGIR	ENSG00000160013	0.84451734329958	[671]	[386,270]	6	hSpCas9	negative selection	1958044
46623995	46624018	19	+	26627737	HCT116	viability after 9 days	GCGCGCATAGGCCACGAACACGG	PTGIR	ENSG00000160013	0.530704619976279	[1753]	[751,616]	4	hSpCas9	negative selection	1958045
46621344	46621367	19	+	26627737	HCT116	viability after 12 days	GACTGCTGTGTGGGAGGCAAGGG	PTGIR	ENSG00000160013	0.5927391213649257	[119]	[81,116,87]	5	hSpCas9	negative selection	2040355
46621410	46621433	19	-	26627737	HCT116	viability after 12 days	TCTGCTCCTGTGGGAAAGGAGGG	PTGIR	ENSG00000160013	0.4592155649248903	[177]	[58,172,160]	4	hSpCas9	negative selection	2040356
46623770	46623793	19	+	26627737	HCT116	viability after 12 days	CGCGCAGAAGAGGACGCAGAAGG	PTGIR	ENSG00000160013	-0.09380289607289949	[508]	[230,345,178]	-1	hSpCas9	negative selection	2040357
46623934	46623957	19	+	26627737	HCT116	viability after 12 days	CGAAGGCGAAGGCATCGCACAGG	PTGIR	ENSG00000160013	-0.9143466342398043	[471]	[111,149,134]	-7	hSpCas9	negative selection	2040358
46623940	46623963	19	+	26627737	HCT116	viability after 12 days	CGAAGGCATCGCACAGGGCGGGG	PTGIR	ENSG00000160013	0.1535871530805908	[549]	[441,323,187]	1	hSpCas9	negative selection	2040359
46623995	46624018	19	+	26627737	HCT116	viability after 12 days	GCGCGCATAGGCCACGAACACGG	PTGIR	ENSG00000160013	0.3943718041778832	[929]	[502,625,809]	4	hSpCas9	negative selection	2040360
46621344	46621367	19	+	26627737	HCT116	viability after 15 days	GACTGCTGTGTGGGAGGCAAGGG	PTGIR	ENSG00000160013	1.3633221874623596	[119]	[124,177,221]	8	hSpCas9	negative selection	2122670
46621410	46621433	19	-	26627737	HCT116	viability after 15 days	TCTGCTCCTGTGGGAAAGGAGGG	PTGIR	ENSG00000160013	0.12759180403821113	[177]	[132,40,162]	1	hSpCas9	negative selection	2122671
46623770	46623793	19	+	26627737	HCT116	viability after 15 days	CGCGCAGAAGAGGACGCAGAAGG	PTGIR	ENSG00000160013	-0.02593014535543048	[508]	[373,301,196]	0	hSpCas9	negative selection	2122672
46623934	46623957	19	+	26627737	HCT116	viability after 15 days	CGAAGGCGAAGGCATCGCACAGG	PTGIR	ENSG00000160013	-0.9955130352142085	[471]	[159,131,118]	-7	hSpCas9	negative selection	2122673
46623940	46623963	19	+	26627737	HCT116	viability after 15 days	CGAAGGCATCGCACAGGGCGGGG	PTGIR	ENSG00000160013	-0.33078072068602027	[549]	[302,226,229]	-3	hSpCas9	negative selection	2122674
46623995	46624018	19	+	26627737	HCT116	viability after 15 days	GCGCGCATAGGCCACGAACACGG	PTGIR	ENSG00000160013	0.5764887891169928	[929]	[772,858,754]	5	hSpCas9	negative selection	2122675
46621344	46621367	19	+	26627737	HCT116	viability after 18 days	GACTGCTGTGTGGGAGGCAAGGG	PTGIR	ENSG00000160013	1.5863462979977947	[119]	[189,155,177]	9	hSpCas9	negative selection	2204985
46621410	46621433	19	-	26627737	HCT116	viability after 18 days	TCTGCTCCTGTGGGAAAGGAGGG	PTGIR	ENSG00000160013	-0.40152946375682075	[177]	[38,53,104]	-4	hSpCas9	negative selection	2204986
46623770	46623793	19	+	26627737	HCT116	viability after 18 days	CGCGCAGAAGAGGACGCAGAAGG	PTGIR	ENSG00000160013	-0.07729690364470099	[508]	[234,212,253]	0	hSpCas9	negative selection	2204987
46623934	46623957	19	+	26627737	HCT116	viability after 18 days	CGAAGGCGAAGGCATCGCACAGG	PTGIR	ENSG00000160013	-0.20341300906322335	[471]	[221,115,264]	-2	hSpCas9	negative selection	2204988
46623940	46623963	19	+	26627737	HCT116	viability after 18 days	CGAAGGCATCGCACAGGGCGGGG	PTGIR	ENSG00000160013	-0.006097637953071944	[549]	[346,250,193]	0	hSpCas9	negative selection	2204989
46623995	46624018	19	+	26627737	HCT116	viability after 18 days	GCGCGCATAGGCCACGAACACGG	PTGIR	ENSG00000160013	1.036975677283616	[929]	[898,903,967]	7	hSpCas9	negative selection	2204990
46624070	46624093	19	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CCAGCACCGCGAAGGCCGAGGGG	PTGIR	ENSG00000160013	0.4532830886623197	[2,2]	[3,3]	8	hSpCas9	positive selection	3014602
46624190	46624213	19	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCAGGAACCTCACCTACGTGCGG	PTGIR	ENSG00000160013	-0.5398879920995534	[3,3]	[3,0]	-7	hSpCas9	positive selection	3014603
46624078	46624101	19	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCGAAGGCCGAGGGGCGCGCCGG	PTGIR	ENSG00000160013	-0.5753492913553488	[2,2]	[1,0]	-7	hSpCas9	positive selection	3014604
46623692	46623715	19	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCTGGGCCCAGCGCATGCGGAGG	PTGIR	ENSG00000160013	0.2229853518291059	[2,2]	[3,2]	5	hSpCas9	positive selection	3014605
46624070	46624093	19	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CCAGCACCGCGAAGGCCGAGGGG	PTGIR	ENSG00000160013	0.16607709578849025	[2,2]	[4,0]	3	hSpCas9	positive selection	3082460
46624190	46624213	19	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCAGGAACCTCACCTACGTGCGG	PTGIR	ENSG00000160013	-1.1782722269151427	[3,3]	[0,0]	-9	hSpCas9	positive selection	3082461
46624078	46624101	19	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCGAAGGCCGAGGGGCGCGCCGG	PTGIR	ENSG00000160013	0.6861901638299122	[2,2]	[1,4]	9	hSpCas9	positive selection	3082462
46623692	46623715	19	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCTGGGCCCAGCGCATGCGGAGG	PTGIR	ENSG00000160013	-0.021095614091346332	[2,2]	[3,0]	0	hSpCas9	positive selection	3082463
46621519	46621542		+	24336571	A375	resistance to PLX after 7 days	AGACCCAGAGCTTGAGTCGCTGG	PTGIR	ENSG00000160013	-0.15171203530872546	[23,20]	[20,18]	-5	hSpCas9	positive selection	3138691
46623995	46624018		+	24336571	A375	resistance to PLX after 7 days	GCGCGCATAGGCCACGAACACGG	PTGIR	ENSG00000160013	-0.5073381460375923	[8,6]	[4,5]	-9	hSpCas9	positive selection	3138692
46621474	46621497		+	24336571	A375	resistance to PLX after 7 days	GGGGTGTCTGCGAGTCTCCGTGG	PTGIR	ENSG00000160013	0.036279701745546955	[2,2]	[2,2]	1	hSpCas9	positive selection	3138693
46621519	46621542		+	24336571	A375	resistance to PLX after 14 days	AGACCCAGAGCTTGAGTCGCTGG	PTGIR	ENSG00000160013	-0.6512072973247345	[17,23]	[5,5]	-7	hSpCas9	positive selection	3196484
46623995	46624018		+	24336571	A375	resistance to PLX after 14 days	GCGCGCATAGGCCACGAACACGG	PTGIR	ENSG00000160013	-0.07493131962842647	[6,3]	[2,1]	0	hSpCas9	positive selection	3196485
46621474	46621497		+	24336571	A375	resistance to PLX after 14 days	GGGGTGTCTGCGAGTCTCCGTGG	PTGIR	ENSG00000160013	0.5234974718217502	[2,1]	[1,1]	5	hSpCas9	positive selection	3196486
46621519	46621542		+	24336571	A375	viability after 7 days	AGACCCAGAGCTTGAGTCGCTGG	PTGIR	ENSG00000160013	0.43670977772444886	[16]	[23,20]	6	hSpCas9	negative selection	3254277
46623995	46624018		+	24336571	A375	viability after 7 days	GCGCGCATAGGCCACGAACACGG	PTGIR	ENSG00000160013	0.09847543982258056	[7]	[8,6]	1	hSpCas9	negative selection	3254278
46621474	46621497		+	24336571	A375	viability after 7 days	GGGGTGTCTGCGAGTCTCCGTGG	PTGIR	ENSG00000160013	-0.188159876233027	[3]	[2,2]	-3	hSpCas9	negative selection	3254279
46621519	46621542		+	24336571	A375	viability after 14 days	AGACCCAGAGCTTGAGTCGCTGG	PTGIR	ENSG00000160013	0.33663951320358976	[16]	[17,23]	4	hSpCas9	negative selection	3312070
46623995	46624018		+	24336571	A375	viability after 14 days	GCGCGCATAGGCCACGAACACGG	PTGIR	ENSG00000160013	-0.3534348210425856	[7]	[6,3]	-4	hSpCas9	negative selection	3312071
46621474	46621497		+	24336571	A375	viability after 14 days	GGGGTGTCTGCGAGTCTCCGTGG	PTGIR	ENSG00000160013	-0.3780350379040769	[3]	[2,1]	-4	hSpCas9	negative selection	3312072
46621310	46621333	19	+	27383988	293T	resistance to West Nile virus (flavivirus)	TGCTTTGGACGACGTTCCCACGG	PTGIR	ENSG00000160013	-1.3500041023037754	[389,389]	[0,0]	-8	hSpCas9	positive selection	3388187
46624039	46624062	19	-	27383988	293T	resistance to West Nile virus (flavivirus)	ACTGGCGGCCACCGACCTGCTGG	PTGIR	ENSG00000160013	0.06750165256581787	[145,145]	[0,0]	0	hSpCas9	positive selection	3388188
46624208	46624231	19	-	27383988	293T	resistance to West Nile virus (flavivirus)	CTGGGATGGCGGATTCGTGCAGG	PTGIR	ENSG00000160013	0.5294057568826359	[105,105]	[0,0]	2	hSpCas9	positive selection	3388189
46624069	46624092	19	+	26780180	HT29	viability (Avana library 4 designs)	CCAGCACCGCGAAGGCCGAGGGG	PTGIR	ENSG00000160013	0.701815431251777	[]	[]	2	hSpCas9	negative selection	3452846
46624190	46624213	19	-	26780180	HT29	viability (Avana library 4 designs)	GCAGGAACCTCACCTACGTGCGG	PTGIR	ENSG00000160013	1.0203960128101	[]	[]	4	hSpCas9	negative selection	3452847
46624077	46624100	19	+	26780180	HT29	viability (Avana library 4 designs)	GCGAAGGCCGAGGGGCGCGCCGG	PTGIR	ENSG00000160013	1.1742880493076	[]	[]	4	hSpCas9	negative selection	3452848
46623691	46623714	19	+	26780180	HT29	viability (Avana library 4 designs)	GCTGGGCCCAGCGCATGCGGAGG	PTGIR	ENSG00000160013	1.49591812276859	[]	[]	6	hSpCas9	negative selection	3452849
46624069	46624092	19	+	26780180	A375	viability (Avana lentiCRISPRv2)	CCAGCACCGCGAAGGCCGAGGGG	PTGIR	ENSG00000160013	3.14002690819103	[]	[]	5	hSpCas9	negative selection	3549416
46624190	46624213	19	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCAGGAACCTCACCTACGTGCGG	PTGIR	ENSG00000160013	1.57643580012545	[]	[]	2	hSpCas9	negative selection	3549417
46623691	46623714	19	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCTGGGCCCAGCGCATGCGGAGG	PTGIR	ENSG00000160013	0.226271869670662	[]	[]	0	hSpCas9	negative selection	3549418
46624077	46624100	19	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCGAAGGCCGAGGGGCGCGCCGG	PTGIR	ENSG00000160013	2.68659823022259	[]	[]	4	hSpCas9	negative selection	3549419
46624054	46624077	19	-	26780180	A375	viability (Avana lentiCRISPRv2)	GGTGCTGGTGACCGGACTGGCGG	PTGIR	ENSG00000160013	4.17757417040479	[]	[]	7	hSpCas9	negative selection	3549420
46624188	46624211	19	-	26780180	A375	viability (Avana lentiCRISPRv2)	AGGAACCTCACCTACGTGCGGGG	PTGIR	ENSG00000160013	5.55161786928882	[]	[]	8	hSpCas9	negative selection	3549421
46624069	46624092	19	+	26780180	A375	viability (Avana lentiGuide)	CCAGCACCGCGAAGGCCGAGGGG	PTGIR	ENSG00000160013	-2.61387528377089	[]	[]	-4	hSpCas9	negative selection	3658075
46624190	46624213	19	-	26780180	A375	viability (Avana lentiGuide)	GCAGGAACCTCACCTACGTGCGG	PTGIR	ENSG00000160013	9.19238796668494	[]	[]	6	hSpCas9	negative selection	3658076
46623691	46623714	19	+	26780180	A375	viability (Avana lentiGuide)	GCTGGGCCCAGCGCATGCGGAGG	PTGIR	ENSG00000160013	6.83467556368865	[]	[]	5	hSpCas9	negative selection	3658077
46624077	46624100	19	+	26780180	A375	viability (Avana lentiGuide)	GCGAAGGCCGAGGGGCGCGCCGG	PTGIR	ENSG00000160013	4.77034625807081	[]	[]	4	hSpCas9	negative selection	3658078
46624054	46624077	19	-	26780180	A375	viability (Avana lentiGuide)	GGTGCTGGTGACCGGACTGGCGG	PTGIR	ENSG00000160013	1.18942968389144	[]	[]	1	hSpCas9	negative selection	3658079
46624188	46624211	19	-	26780180	A375	viability (Avana lentiGuide)	AGGAACCTCACCTACGTGCGGGG	PTGIR	ENSG00000160013	1.65885347046093	[]	[]	2	hSpCas9	negative selection	3658080
46624069	46624092	19	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CCAGCACCGCGAAGGCCGAGGGG	PTGIR	ENSG00000160013	0.19354280960679265	[3]	[5,3]	5	hSpCas9	positive selection	3766682
46624190	46624213	19	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCAGGAACCTCACCTACGTGCGG	PTGIR	ENSG00000160013	0.05691349607540033	[4]	[4,4]	1	hSpCas9	positive selection	3766683
46623691	46623714	19	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCTGGGCCCAGCGCATGCGGAGG	PTGIR	ENSG00000160013	-0.2098046991480731	[3]	[2,2]	-3	hSpCas9	positive selection	3766684
46624077	46624100	19	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCGAAGGCCGAGGGGCGCGCCGG	PTGIR	ENSG00000160013	0.2636940761728946	[4]	[4,5]	7	hSpCas9	positive selection	3766685
46624054	46624077	19	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGTGCTGGTGACCGGACTGGCGG	PTGIR	ENSG00000160013	0.37253212668925995	[4]	[6,5]	9	hSpCas9	positive selection	3766686
46624188	46624211	19	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AGGAACCTCACCTACGTGCGGGG	PTGIR	ENSG00000160013	0.33222090841301166	[5]	[7,7]	8	hSpCas9	positive selection	3766687
46624069	46624092	19	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CCAGCACCGCGAAGGCCGAGGGG	PTGIR	ENSG00000160013	0.1954214931162128	[4]	[4,4]	5	hSpCas9	positive selection	3875289
46624190	46624213	19	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCAGGAACCTCACCTACGTGCGG	PTGIR	ENSG00000160013	-0.6658819958314778	[5]	[2,2]	-7	hSpCas9	positive selection	3875290
46623691	46623714	19	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCTGGGCCCAGCGCATGCGGAGG	PTGIR	ENSG00000160013	-0.46370490538870934	[4]	[0,3]	-5	hSpCas9	positive selection	3875291
46624077	46624100	19	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCGAAGGCCGAGGGGCGCGCCGG	PTGIR	ENSG00000160013	-0.2888991464242721	[5]	[3,3]	-4	hSpCas9	positive selection	3875292
46624054	46624077	19	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGTGCTGGTGACCGGACTGGCGG	PTGIR	ENSG00000160013	0.27326777819007697	[5]	[4,6]	7	hSpCas9	positive selection	3875293
46624188	46624211	19	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AGGAACCTCACCTACGTGCGGGG	PTGIR	ENSG00000160013	-0.005119579564741544	[6]	[6,4]	0	hSpCas9	positive selection	3875294
46624039	46624062	19	-	26780180	A375	viability	ACTGGCGGCCACCGACCTGCTGG	PTGIR	ENSG00000160013	1.58153792306813	[]	[]	8	hSpCas9	negative selection	3985719
46621377	46621400	19	+	26780180	A375	viability	CCCTCGCCCCAAGCCGACAAAGG	PTGIR	ENSG00000160013	0.748340907155164	[]	[]	2	hSpCas9	negative selection	3985720
46624208	46624231	19	-	26780180	A375	viability	CTGGGATGGCGGATTCGTGCAGG	PTGIR	ENSG00000160013	0.985262271165295	[]	[]	4	hSpCas9	negative selection	3985721
46623995	46624018	19	+	26780180	A375	viability	GCGCGCATAGGCCACGAACACGG	PTGIR	ENSG00000160013	0.952971553808716	[]	[]	4	hSpCas9	negative selection	3985722
46624061	46624084	19	+	26780180	A375	viability	TCCGGTCACCAGCACCGCGAAGG	PTGIR	ENSG00000160013	1.0907398429333	[]	[]	5	hSpCas9	negative selection	3985723
46621310	46621333	19	+	26780180	A375	viability	TGCTTTGGACGACGTTCCCACGG	PTGIR	ENSG00000160013	1.1682204098059	[]	[]	6	hSpCas9	negative selection	3985724
46624039	46624062	19	-	26780180	HT29	viability (GeCKOv2 library)	ACTGGCGGCCACCGACCTGCTGG	PTGIR	ENSG00000160013	1.42342292453279	[]	[]	7	hSpCas9	negative selection	4093685
46621377	46621400	19	+	26780180	HT29	viability (GeCKOv2 library)	CCCTCGCCCCAAGCCGACAAAGG	PTGIR	ENSG00000160013	1.19409082750576	[]	[]	6	hSpCas9	negative selection	4093686
46624208	46624231	19	-	26780180	HT29	viability (GeCKOv2 library)	CTGGGATGGCGGATTCGTGCAGG	PTGIR	ENSG00000160013	1.830435198088	[]	[]	8	hSpCas9	negative selection	4093687
46623995	46624018	19	+	26780180	HT29	viability (GeCKOv2 library)	GCGCGCATAGGCCACGAACACGG	PTGIR	ENSG00000160013	0.543914198372761	[]	[]	1	hSpCas9	negative selection	4093688
46624061	46624084	19	+	26780180	HT29	viability (GeCKOv2 library)	TCCGGTCACCAGCACCGCGAAGG	PTGIR	ENSG00000160013	1.20477366948682	[]	[]	6	hSpCas9	negative selection	4093689
46621310	46621333	19	+	26780180	HT29	viability (GeCKOv2 library)	TGCTTTGGACGACGTTCCCACGG	PTGIR	ENSG00000160013	1.13648337767989	[]	[]	5	hSpCas9	negative selection	4093690
46621519	46621542	19	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	AGACCCAGAGCTTGAGTCGCTGG	PTGIR	ENSG00000160013	-0.10927027722756191	[4]	[2,2]	-3	hSpCas9	positive selection	4163946
46623995	46624018	19	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GCGCGCATAGGCCACGAACACGG	PTGIR	ENSG00000160013	-0.01770149415776845	[2]	[2,0]	0	hSpCas9	positive selection	4163947
46621474	46621497	19	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GGGGTGTCTGCGAGTCTCCGTGG	PTGIR	ENSG00000160013	-0.32155178115596894	[1]	[1,0]	-7	hSpCas9	positive selection	4163948
46621519	46621542	19	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	AGACCCAGAGCTTGAGTCGCTGG	PTGIR	ENSG00000160013	0.9108387518992828	[3]	[0,3,2,3]	6	hSpCas9	positive selection	4227968
46623995	46624018	19	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GCGCGCATAGGCCACGAACACGG	PTGIR	ENSG00000160013	-0.008426042388544053	[1]	[0,0,0,0]	0	hSpCas9	positive selection	4227969
46621474	46621497	19	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GGGGTGTCTGCGAGTCTCCGTGG	PTGIR	ENSG00000160013	1.0419167629236492	[0]	[0,0,0,0]	7	hSpCas9	positive selection	4227970
46623995	46624018	19	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GCGCGCATAGGCCACGAACACGG	PTGIR	ENSG00000160013	0.0825627721416693	[3]	[2,2]	1	hSpCas9	positive selection	4292978
46624061	46624084	19	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TCCGGTCACCAGCACCGCGAAGG	PTGIR	ENSG00000160013	-0.18291940018606365	[3]	[2,1]	-4	hSpCas9	positive selection	4292979
46621377	46621400	19	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCCTCGCCCCAAGCCGACAAAGG	PTGIR	ENSG00000160013	0.35545920456093205	[1]	[2,0]	7	hSpCas9	positive selection	4292980
46621310	46621333	19	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TGCTTTGGACGACGTTCCCACGG	PTGIR	ENSG00000160013	0.08996390733819448	[4]	[3,3]	1	hSpCas9	positive selection	4357237
46624039	46624062	19	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ACTGGCGGCCACCGACCTGCTGG	PTGIR	ENSG00000160013	0.08780748930853201	[2]	[2,1]	1	hSpCas9	positive selection	4357238
46624208	46624231	19	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CTGGGATGGCGGATTCGTGCAGG	PTGIR	ENSG00000160013	-0.6204138586380149	[2]	[1,0]	-8	hSpCas9	positive selection	4357239
46623657	46623679	19	+	27760321	OCIAML3	viability	CCGGCGTAGGCCAGCGAGAAGG	PTGIR	ENSG00000160013	0.023055331768192078	[366,283]	[192,339]	0	hSpCas9	negative selection	4431764
46623831	46623853	19	-	27760321	OCIAML3	viability	ACCTCTACGCGCAGCTGGACGG	PTGIR	ENSG00000160013	0.7634219079308937	[622,574]	[664,964]	8	hSpCas9	negative selection	4431765
46623941	46623963	19	+	27760321	OCIAML3	viability	GAAGGCATCGCACAGGGCGGGG	PTGIR	ENSG00000160013	-0.07139547637926125	[842,629]	[549,534]	-1	hSpCas9	negative selection	4431766
46623996	46624018	19	+	27760321	OCIAML3	viability	CGCGCATAGGCCACGAACACGG	PTGIR	ENSG00000160013	-0.7891233464809686	[536,432]	[239,189]	-6	hSpCas9	negative selection	4431767
46624096	46624118	19	-	27760321	OCIAML3	viability	ATCCTGAGCGCACGGCGACCGG	PTGIR	ENSG00000160013	0.2974069504111151	[593,486]	[529,499]	3	hSpCas9	negative selection	4431768
46623657	46623679	19	+	27760321	OCIAML2	viability	CCGGCGTAGGCCAGCGAGAAGG	PTGIR	ENSG00000160013	-0.0029511043917870294	[366,283]	[234,294]	0	hSpCas9	negative selection	4515227
46623831	46623853	19	-	27760321	OCIAML2	viability	ACCTCTACGCGCAGCTGGACGG	PTGIR	ENSG00000160013	0.36339285635696084	[622,574]	[527,748]	5	hSpCas9	negative selection	4515228
46623941	46623963	19	+	27760321	OCIAML2	viability	GAAGGCATCGCACAGGGCGGGG	PTGIR	ENSG00000160013	0.3461035759643465	[842,629]	[774,718]	5	hSpCas9	negative selection	4515229
46623996	46624018	19	+	27760321	OCIAML2	viability	CGCGCATAGGCCACGAACACGG	PTGIR	ENSG00000160013	-0.4453941349866676	[536,432]	[248,335]	-5	hSpCas9	negative selection	4515230
46624096	46624118	19	-	27760321	OCIAML2	viability	ATCCTGAGCGCACGGCGACCGG	PTGIR	ENSG00000160013	-0.13320473293729343	[593,486]	[328,485]	-2	hSpCas9	negative selection	4515231
46623657	46623679	19	+	27760321	MV411	viability	CCGGCGTAGGCCAGCGAGAAGG	PTGIR	ENSG00000160013	-0.43470165949643297	[366,283]	[128,200]	-3	hSpCas9	negative selection	4598690
46623831	46623853	19	-	27760321	MV411	viability	ACCTCTACGCGCAGCTGGACGG	PTGIR	ENSG00000160013	-0.05680162881729173	[622,574]	[160,708]	0	hSpCas9	negative selection	4598691
46623941	46623963	19	+	27760321	MV411	viability	GAAGGCATCGCACAGGGCGGGG	PTGIR	ENSG00000160013	1.1251287981727167	[842,629]	[1295,682]	7	hSpCas9	negative selection	4598692
46623996	46624018	19	+	27760321	MV411	viability	CGCGCATAGGCCACGAACACGG	PTGIR	ENSG00000160013	-0.38644715929380746	[536,432]	[354,75]	-3	hSpCas9	negative selection	4598693
46624096	46624118	19	-	27760321	MV411	viability	ATCCTGAGCGCACGGCGACCGG	PTGIR	ENSG00000160013	-1.9177732424363354	[593,486]	[23,198]	-8	hSpCas9	negative selection	4598694
46623657	46623679	19	+	27760321	HL60	viability	CCGGCGTAGGCCAGCGAGAAGG	PTGIR	ENSG00000160013	-0.20874532029017673	[366,283]	[258,195]	-2	hSpCas9	negative selection	4682153
46623831	46623853	19	-	27760321	HL60	viability	ACCTCTACGCGCAGCTGGACGG	PTGIR	ENSG00000160013	0.6618270507264368	[622,574]	[827,716]	7	hSpCas9	negative selection	4682154
46623941	46623963	19	+	27760321	HL60	viability	GAAGGCATCGCACAGGGCGGGG	PTGIR	ENSG00000160013	0.30669328945451646	[842,629]	[745,728]	4	hSpCas9	negative selection	4682155
46623996	46624018	19	+	27760321	HL60	viability	CGCGCATAGGCCACGAACACGG	PTGIR	ENSG00000160013	-0.2913404157710303	[536,432]	[336,305]	-3	hSpCas9	negative selection	4682156
46624096	46624118	19	-	27760321	HL60	viability	ATCCTGAGCGCACGGCGACCGG	PTGIR	ENSG00000160013	-0.384743916685145	[593,486]	[320,352]	-4	hSpCas9	negative selection	4682157
46623657	46623679	19	+	27760321	HT1080	viability	CCGGCGTAGGCCAGCGAGAAGG	PTGIR	ENSG00000160013	1.5595438709984393	[283,221]	[446,132]	8	hSpCas9	negative selection	4765616
46623831	46623853	19	-	27760321	HT1080	viability	ACCTCTACGCGCAGCTGGACGG	PTGIR	ENSG00000160013	1.2493938752759584	[574,448]	[651,301]	6	hSpCas9	negative selection	4765617
46623941	46623963	19	+	27760321	HT1080	viability	GAAGGCATCGCACAGGGCGGGG	PTGIR	ENSG00000160013	0.051543207221950826	[629,491]	[170,297]	0	hSpCas9	negative selection	4765618
46623996	46624018	19	+	27760321	HT1080	viability	CGCGCATAGGCCACGAACACGG	PTGIR	ENSG00000160013	-0.9958685590476573	[432,337]	[34,122]	-4	hSpCas9	negative selection	4765619
46624096	46624118	19	-	27760321	HT1080	viability	ATCCTGAGCGCACGGCGACCGG	PTGIR	ENSG00000160013	-0.4901496334792418	[486,379]	[163,77]	-2	hSpCas9	negative selection	4765620
46623657	46623679	19	+	27760321	HT29	viability after 7 days	CCGGCGTAGGCCAGCGAGAAGG	PTGIR	ENSG00000160013	0.2745967731051948	[283,221]	[537,281,380]	4	hSpCas9	negative selection	4849079
46623831	46623853	19	-	27760321	HT29	viability after 7 days	ACCTCTACGCGCAGCTGGACGG	PTGIR	ENSG00000160013	0.1452969296143488	[574,448]	[566,732,855]	2	hSpCas9	negative selection	4849080
46623941	46623963	19	+	27760321	HT29	viability after 7 days	GAAGGCATCGCACAGGGCGGGG	PTGIR	ENSG00000160013	0.7507870891289369	[629,491]	[1208,1093,1331]	9	hSpCas9	negative selection	4849081
46623996	46624018	19	+	27760321	HT29	viability after 7 days	CGCGCATAGGCCACGAACACGG	PTGIR	ENSG00000160013	-0.041950209855626155	[432,337]	[497,593,357]	0	hSpCas9	negative selection	4849082
46624096	46624118	19	-	27760321	HT29	viability after 7 days	ATCCTGAGCGCACGGCGACCGG	PTGIR	ENSG00000160013	-0.004968589430733195	[486,379]	[640,649,391]	0	hSpCas9	negative selection	4849083
46623657	46623679	19	+	27760321	HT29	viability after 25 days	CCGGCGTAGGCCAGCGAGAAGG	PTGIR	ENSG00000160013	-0.25948100485975323	[283,221]	[282,254,176]	-3	hSpCas9	negative selection	4932542
46623831	46623853	19	-	27760321	HT29	viability after 25 days	ACCTCTACGCGCAGCTGGACGG	PTGIR	ENSG00000160013	0.4155770976718933	[574,448]	[740,913,676]	4	hSpCas9	negative selection	4932543
46623941	46623963	19	+	27760321	HT29	viability after 25 days	GAAGGCATCGCACAGGGCGGGG	PTGIR	ENSG00000160013	0.31617914004899916	[629,491]	[827,796,762]	3	hSpCas9	negative selection	4932544
46623996	46624018	19	+	27760321	HT29	viability after 25 days	CGCGCATAGGCCACGAACACGG	PTGIR	ENSG00000160013	0.07491138964444334	[432,337]	[273,461,690]	0	hSpCas9	negative selection	4932545
46624096	46624118	19	-	27760321	HT29	viability after 25 days	ATCCTGAGCGCACGGCGACCGG	PTGIR	ENSG00000160013	-0.14006583967836064	[486,379]	[510,384,447]	-1	hSpCas9	negative selection	4932546
46623657	46623679	19	+	27760321	HT29	viability after 22 days	CCGGCGTAGGCCAGCGAGAAGG	PTGIR	ENSG00000160013	0.6371701957217277	[283,221]	[616,329,412]	7	hSpCas9	negative selection	5016005
46623831	46623853	19	-	27760321	HT29	viability after 22 days	ACCTCTACGCGCAGCTGGACGG	PTGIR	ENSG00000160013	0.04267978732509581	[574,448]	[573,646,608]	0	hSpCas9	negative selection	5016006
46623941	46623963	19	+	27760321	HT29	viability after 22 days	GAAGGCATCGCACAGGGCGGGG	PTGIR	ENSG00000160013	0.7050704783286051	[629,491]	[884,1082,1209]	7	hSpCas9	negative selection	5016007
46623996	46624018	19	+	27760321	HT29	viability after 22 days	CGCGCATAGGCCACGAACACGG	PTGIR	ENSG00000160013	0.28834324215202245	[432,337]	[566,430,634]	3	hSpCas9	negative selection	5016008
46624096	46624118	19	-	27760321	HT29	viability after 22 days	ATCCTGAGCGCACGGCGACCGG	PTGIR	ENSG00000160013	0.0839646193623757	[486,379]	[422,476,697]	0	hSpCas9	negative selection	5016009
46623657	46623679	19	+	27760321	HT29	viability after 19 days	CCGGCGTAGGCCAGCGAGAAGG	PTGIR	ENSG00000160013	0.09483816275357798	[283,221]	[439,308,195]	0	hSpCas9	negative selection	5099468
46623831	46623853	19	-	27760321	HT29	viability after 19 days	ACCTCTACGCGCAGCTGGACGG	PTGIR	ENSG00000160013	0.5345402014469712	[574,448]	[781,930,824]	5	hSpCas9	negative selection	5099469
46623941	46623963	19	+	27760321	HT29	viability after 19 days	GAAGGCATCGCACAGGGCGGGG	PTGIR	ENSG00000160013	0.4687813450948869	[629,491]	[1491,733,514]	4	hSpCas9	negative selection	5099470
46623996	46624018	19	+	27760321	HT29	viability after 19 days	CGCGCATAGGCCACGAACACGG	PTGIR	ENSG00000160013	-0.2047934022249182	[432,337]	[558,415,197]	-2	hSpCas9	negative selection	5099471
46624096	46624118	19	-	27760321	HT29	viability after 19 days	ATCCTGAGCGCACGGCGACCGG	PTGIR	ENSG00000160013	-0.19830308234143723	[486,379]	[758,346,231]	-2	hSpCas9	negative selection	5099472
46623657	46623679	19	+	27760321	HT29	viability after 16 days	CCGGCGTAGGCCAGCGAGAAGG	PTGIR	ENSG00000160013	-0.029317826986862472	[283,221]	[329,395,107]	0	hSpCas9	negative selection	5182931
46623831	46623853	19	-	27760321	HT29	viability after 16 days	ACCTCTACGCGCAGCTGGACGG	PTGIR	ENSG00000160013	-0.127117333236817	[574,448]	[483,588,494]	-1	hSpCas9	negative selection	5182932
46623941	46623963	19	+	27760321	HT29	viability after 16 days	GAAGGCATCGCACAGGGCGGGG	PTGIR	ENSG00000160013	0.3655461921678941	[629,491]	[659,802,948]	4	hSpCas9	negative selection	5182933
46623996	46624018	19	+	27760321	HT29	viability after 16 days	CGCGCATAGGCCACGAACACGG	PTGIR	ENSG00000160013	0.4391225310738796	[432,337]	[580,768,398]	5	hSpCas9	negative selection	5182934
46624096	46624118	19	-	27760321	HT29	viability after 16 days	ATCCTGAGCGCACGGCGACCGG	PTGIR	ENSG00000160013	-0.15287082255414736	[486,379]	[243,683,355]	-2	hSpCas9	negative selection	5182935
46623657	46623679	19	+	27760321	HT29	viability after 13 days	CCGGCGTAGGCCAGCGAGAAGG	PTGIR	ENSG00000160013	0.269817813657318	[283,221]	[351,446,267]	3	hSpCas9	negative selection	5266394
46623831	46623853	19	-	27760321	HT29	viability after 13 days	ACCTCTACGCGCAGCTGGACGG	PTGIR	ENSG00000160013	0.4489975845366352	[574,448]	[791,889,753]	6	hSpCas9	negative selection	5266395
46623941	46623963	19	+	27760321	HT29	viability after 13 days	GAAGGCATCGCACAGGGCGGGG	PTGIR	ENSG00000160013	0.6838925949084004	[629,491]	[1099,1103,938]	8	hSpCas9	negative selection	5266396
46623996	46624018	19	+	27760321	HT29	viability after 13 days	CGCGCATAGGCCACGAACACGG	PTGIR	ENSG00000160013	-0.07925253418020527	[432,337]	[359,400,503]	-1	hSpCas9	negative selection	5266397
46624096	46624118	19	-	27760321	HT29	viability after 13 days	ATCCTGAGCGCACGGCGACCGG	PTGIR	ENSG00000160013	-0.43464762499467363	[486,379]	[400,255,453]	-5	hSpCas9	negative selection	5266398
46623657	46623679	19	+	27760321	HT29	viability after 10 days	CCGGCGTAGGCCAGCGAGAAGG	PTGIR	ENSG00000160013	-0.27185298452237383	[283,221]	[189,254,337]	-3	hSpCas9	negative selection	5349857
46623831	46623853	19	-	27760321	HT29	viability after 10 days	ACCTCTACGCGCAGCTGGACGG	PTGIR	ENSG00000160013	0.1613391953118063	[574,448]	[675,598,862]	2	hSpCas9	negative selection	5349858
46623941	46623963	19	+	27760321	HT29	viability after 10 days	GAAGGCATCGCACAGGGCGGGG	PTGIR	ENSG00000160013	0.6169316976531399	[629,491]	[1147,929,1138]	8	hSpCas9	negative selection	5349859
46623996	46624018	19	+	27760321	HT29	viability after 10 days	CGCGCATAGGCCACGAACACGG	PTGIR	ENSG00000160013	-0.0059168157191472615	[432,337]	[453,450,530]	0	hSpCas9	negative selection	5349860
46624096	46624118	19	-	27760321	HT29	viability after 10 days	ATCCTGAGCGCACGGCGACCGG	PTGIR	ENSG00000160013	0.2109832268373063	[486,379]	[532,701,645]	2	hSpCas9	negative selection	5349861
46623657	46623679	19	+	27760321	MOLM13	viability	CCGGCGTAGGCCAGCGAGAAGG	PTGIR	ENSG00000160013	-3.3029636818584565	[366,283]	[38,0]	-9	hSpCas9	negative selection	5433320
46623831	46623853	19	-	27760321	MOLM13	viability	ACCTCTACGCGCAGCTGGACGG	PTGIR	ENSG00000160013	0.17810084091051048	[622,574]	[733,82]	1	hSpCas9	negative selection	5433321
46623941	46623963	19	+	27760321	MOLM13	viability	GAAGGCATCGCACAGGGCGGGG	PTGIR	ENSG00000160013	-0.5338570515132759	[842,629]	[135,410]	-3	hSpCas9	negative selection	5433322
46623996	46624018	19	+	27760321	MOLM13	viability	CGCGCATAGGCCACGAACACGG	PTGIR	ENSG00000160013	-0.7798581743221967	[536,432]	[50,249]	-5	hSpCas9	negative selection	5433323
46624096	46624118	19	-	27760321	MOLM13	viability	ATCCTGAGCGCACGGCGACCGG	PTGIR	ENSG00000160013	-1.6472345830454467	[593,486]	[84,106]	-7	hSpCas9	negative selection	5433324
46625060	46625083	19	+	27661255	K562	viability	GTGTCTCTCGCTGCCTGTGTCGG	PTGIR	ENSG00000160013	0.04788424429646765	[1448,1339]	[1191,1119]	1	dCas9-KRAB	negative selection	5505131
46624897	46624920	19	-	27661255	K562	viability	GGGGAGGACAAGGACAAGGGAGG	PTGIR	ENSG00000160013	0.2905249669737882	[404,505]	[439,445]	8	dCas9-KRAB	negative selection	5505132
46624917	46624940	19	-	27661255	K562	viability	GGTTAGAGGGAGAAAGGTACGGG	PTGIR	ENSG00000160013	-0.11859404169793031	[577,629]	[521,376]	-4	dCas9-KRAB	negative selection	5505133
46624984	46625007	19	-	27661255	K562	viability	GACTGGAGAGGTGCGGTGAGGGG	PTGIR	ENSG00000160013	0.23069404622736145	[700,953]	[813,734]	7	dCas9-KRAB	negative selection	5505134
46624996	46625019	19	-	27661255	K562	viability	GAGCCTGGGCAAGACTGGAGAGG	PTGIR	ENSG00000160013	-0.08648120945795656	[1321,1188]	[1103,811]	-3	dCas9-KRAB	negative selection	5505135
46623995	46624018	19	+	27260156	BXPC3	viability	GCGCGCATAGGCCACGAACACGG	PTGIR	ENSG00000160013	-0.19672338432201536	[584]	[508,558,464,606]	-4	hSpCas9	negative selection	5565438
46624061	46624084	19	+	27260156	BXPC3	viability	TCCGGTCACCAGCACCGCGAAGG	PTGIR	ENSG00000160013	0.19751898721853287	[474]	[502,524,639,623]	4	hSpCas9	negative selection	5565439
46621377	46621400	19	+	27260156	BXPC3	viability	CCCTCGCCCCAAGCCGACAAAGG	PTGIR	ENSG00000160013	0.5257732593412803	[122]	[223,165,149,196]	9	hSpCas9	negative selection	5565440
46621310	46621333	19	+	27260156	BXPC3	viability	TGCTTTGGACGACGTTCCCACGG	PTGIR	ENSG00000160013	-0.6003965357577947	[1474]	[1030,796,1083,1182]	-8	hSpCas9	negative selection	5629697
46624039	46624062	19	-	27260156	BXPC3	viability	ACTGGCGGCCACCGACCTGCTGG	PTGIR	ENSG00000160013	-0.09498853129207424	[383]	[331,409,302,468]	-2	hSpCas9	negative selection	5629698
46624208	46624231	19	-	27260156	BXPC3	viability	CTGGGATGGCGGATTCGTGCAGG	PTGIR	ENSG00000160013	-0.4726041913246788	[303]	[321,109,274,201]	-8	hSpCas9	negative selection	5629699
46623995	46624018	19	+	27260156	A673	viability	GCGCGCATAGGCCACGAACACGG	PTGIR	ENSG00000160013	-0.10381546613297149	[584]	[568,657,587,796]	-3	hSpCas9	negative selection	5686689
46624061	46624084	19	+	27260156	A673	viability	TCCGGTCACCAGCACCGCGAAGG	PTGIR	ENSG00000160013	0.30729424899074026	[474]	[955,686,689,506]	7	hSpCas9	negative selection	5686690
46621377	46621400	19	+	27260156	A673	viability	CCCTCGCCCCAAGCCGACAAAGG	PTGIR	ENSG00000160013	0.5062627565460123	[122]	[239,161,219,221]	9	hSpCas9	negative selection	5686691
46621310	46621333	19	+	27260156	A673	viability	TGCTTTGGACGACGTTCCCACGG	PTGIR	ENSG00000160013	-0.28620368043775546	[1474]	[1436,1423,1538,1401]	-6	hSpCas9	negative selection	5750948
46624039	46624062	19	-	27260156	A673	viability	ACTGGCGGCCACCGACCTGCTGG	PTGIR	ENSG00000160013	-0.025877966408923148	[383]	[455,377,514,463]	0	hSpCas9	negative selection	5750949
46624208	46624231	19	-	27260156	A673	viability	CTGGGATGGCGGATTCGTGCAGG	PTGIR	ENSG00000160013	-0.17600886131660232	[303]	[310,278,377,322]	-4	hSpCas9	negative selection	5750950
46623995	46624018	19	+	27260156	A375	viability	GCGCGCATAGGCCACGAACACGG	PTGIR	ENSG00000160013	-0.2184809774559967	[584]	[771,483,603,485]	-3	hSpCas9	negative selection	5807940
46624061	46624084	19	+	27260156	A375	viability	TCCGGTCACCAGCACCGCGAAGG	PTGIR	ENSG00000160013	0.30732298044364603	[474]	[630,595,637,845]	4	hSpCas9	negative selection	5807941
46621377	46621400	19	+	27260156	A375	viability	CCCTCGCCCCAAGCCGACAAAGG	PTGIR	ENSG00000160013	0.7054135336672054	[122]	[177,185,339,225]	9	hSpCas9	negative selection	5807942
46621310	46621333	19	+	27260156	A375	viability	TGCTTTGGACGACGTTCCCACGG	PTGIR	ENSG00000160013	-0.7711216542085464	[1474]	[1131,1258,866,832]	-7	hSpCas9	negative selection	5872199
46624039	46624062	19	-	27260156	A375	viability	ACTGGCGGCCACCGACCTGCTGG	PTGIR	ENSG00000160013	0.13493902141202593	[383]	[392,499,468,593]	2	hSpCas9	negative selection	5872200
46624208	46624231	19	-	27260156	A375	viability	CTGGGATGGCGGATTCGTGCAGG	PTGIR	ENSG00000160013	0.14539006856400427	[303]	[403,463,407,312]	2	hSpCas9	negative selection	5872201
46623995	46624018	19	+	27260156	COLO741	viability	GCGCGCATAGGCCACGAACACGG	PTGIR	ENSG00000160013	-0.2543143293206682	[584]	[680,685,523]	-5	hSpCas9	negative selection	5929191
46624061	46624084	19	+	27260156	COLO741	viability	TCCGGTCACCAGCACCGCGAAGG	PTGIR	ENSG00000160013	0.3994219122914341	[474]	[882,840,690]	7	hSpCas9	negative selection	5929192
46621377	46621400	19	+	27260156	COLO741	viability	CCCTCGCCCCAAGCCGACAAAGG	PTGIR	ENSG00000160013	0.4180813564105106	[122]	[215,245,170]	8	hSpCas9	negative selection	5929193
46621310	46621333	19	+	27260156	COLO741	viability	TGCTTTGGACGACGTTCCCACGG	PTGIR	ENSG00000160013	-0.5245412769611975	[1474]	[1332,1238,1353]	-8	hSpCas9	negative selection	5993450
46624039	46624062	19	-	27260156	COLO741	viability	ACTGGCGGCCACCGACCTGCTGG	PTGIR	ENSG00000160013	0.20002828063170608	[383]	[687,533,483]	4	hSpCas9	negative selection	5993451
46624208	46624231	19	-	27260156	COLO741	viability	CTGGGATGGCGGATTCGTGCAGG	PTGIR	ENSG00000160013	-0.1829396656015293	[303]	[422,372,243]	-4	hSpCas9	negative selection	5993452
46623995	46624018	19	+	27260156	CAL120	viability	GCGCGCATAGGCCACGAACACGG	PTGIR	ENSG00000160013	0.4265715214875791	[584]	[1367,621,1002]	6	hSpCas9	negative selection	6050442
46624061	46624084	19	+	27260156	CAL120	viability	TCCGGTCACCAGCACCGCGAAGG	PTGIR	ENSG00000160013	0.40009475919955223	[474]	[884,888,584]	6	hSpCas9	negative selection	6050443
46621377	46621400	19	+	27260156	CAL120	viability	CCCTCGCCCCAAGCCGACAAAGG	PTGIR	ENSG00000160013	0.6294551336152507	[122]	[211,228,264]	8	hSpCas9	negative selection	6050444
46621310	46621333	19	+	27260156	CAL120	viability	TGCTTTGGACGACGTTCCCACGG	PTGIR	ENSG00000160013	0.051734426536575784	[1474]	[2118,1927,1695]	0	hSpCas9	negative selection	6114701
46624039	46624062	19	-	27260156	CAL120	viability	ACTGGCGGCCACCGACCTGCTGG	PTGIR	ENSG00000160013	0.7263616894193797	[383]	[936,585,868]	9	hSpCas9	negative selection	6114702
46624208	46624231	19	-	27260156	CAL120	viability	CTGGGATGGCGGATTCGTGCAGG	PTGIR	ENSG00000160013	-0.06168270764516992	[303]	[447,283,367]	-1	hSpCas9	negative selection	6114703
46623995	46624018	19	+	27260156	CADOES1	viability	GCGCGCATAGGCCACGAACACGG	PTGIR	ENSG00000160013	-0.011092362505828235	[584]	[527,431,568,633]	0	hSpCas9	negative selection	6171693
46624061	46624084	19	+	27260156	CADOES1	viability	TCCGGTCACCAGCACCGCGAAGG	PTGIR	ENSG00000160013	-0.2617339462111859	[474]	[363,423,369,313]	-4	hSpCas9	negative selection	6171694
46621377	46621400	19	+	27260156	CADOES1	viability	CCCTCGCCCCAAGCCGACAAAGG	PTGIR	ENSG00000160013	0.5202975173701971	[122]	[255,96,187,112]	8	hSpCas9	negative selection	6171695
46621310	46621333	19	+	27260156	CADOES1	viability	TGCTTTGGACGACGTTCCCACGG	PTGIR	ENSG00000160013	-0.6782256256992947	[1474]	[1034,722,825,843]	-8	hSpCas9	negative selection	6235952
46624039	46624062	19	-	27260156	CADOES1	viability	ACTGGCGGCCACCGACCTGCTGG	PTGIR	ENSG00000160013	-0.030237905020324918	[383]	[441,399,253,300]	0	hSpCas9	negative selection	6235953
46624208	46624231	19	-	27260156	CADOES1	viability	CTGGGATGGCGGATTCGTGCAGG	PTGIR	ENSG00000160013	-0.3818063247959893	[303]	[149,250,331,131]	-6	hSpCas9	negative selection	6235954
46623995	46624018	19	+	27260156	EWS502	viability	GCGCGCATAGGCCACGAACACGG	PTGIR	ENSG00000160013	0.071992016122356	[584]	[619,574,768,646]	1	hSpCas9	negative selection	6292944
46624061	46624084	19	+	27260156	EWS502	viability	TCCGGTCACCAGCACCGCGAAGG	PTGIR	ENSG00000160013	0.311971447625962	[474]	[522,563,625,810]	5	hSpCas9	negative selection	6292945
46621377	46621400	19	+	27260156	EWS502	viability	CCCTCGCCCCAAGCCGACAAAGG	PTGIR	ENSG00000160013	0.7839738208459417	[122]	[150,228,256,271]	9	hSpCas9	negative selection	6292946
46621310	46621333	19	+	27260156	EWS502	viability	TGCTTTGGACGACGTTCCCACGG	PTGIR	ENSG00000160013	-0.7323060691510015	[1474]	[711,930,1057,1097]	-8	hSpCas9	negative selection	6357203
46624039	46624062	19	-	27260156	EWS502	viability	ACTGGCGGCCACCGACCTGCTGG	PTGIR	ENSG00000160013	-0.0040455368467167685	[383]	[380,256,481,518]	0	hSpCas9	negative selection	6357204
46624208	46624231	19	-	27260156	EWS502	viability	CTGGGATGGCGGATTCGTGCAGG	PTGIR	ENSG00000160013	-0.15674343361980547	[303]	[193,307,361,302]	-3	hSpCas9	negative selection	6357205
46623995	46624018	19	+	27260156	EW8	viability	GCGCGCATAGGCCACGAACACGG	PTGIR	ENSG00000160013	-0.28835391078418104	[584]	[574,283,297,429]	-5	hSpCas9	negative selection	6414195
46624061	46624084	19	+	27260156	EW8	viability	TCCGGTCACCAGCACCGCGAAGG	PTGIR	ENSG00000160013	0.22071887755957578	[474]	[622,493,334,379]	4	hSpCas9	negative selection	6414196
46621377	46621400	19	+	27260156	EW8	viability	CCCTCGCCCCAAGCCGACAAAGG	PTGIR	ENSG00000160013	-0.04405781097437633	[122]	[125,69,69,127]	-1	hSpCas9	negative selection	6414197
46621310	46621333	19	+	27260156	EW8	viability	TGCTTTGGACGACGTTCCCACGG	PTGIR	ENSG00000160013	-0.4973437606060682	[1474]	[1085,860,617,884]	-7	hSpCas9	negative selection	6478454
46624039	46624062	19	-	27260156	EW8	viability	ACTGGCGGCCACCGACCTGCTGG	PTGIR	ENSG00000160013	-0.1550631809367254	[383]	[307,331,217,272]	-3	hSpCas9	negative selection	6478455
46624208	46624231	19	-	27260156	EW8	viability	CTGGGATGGCGGATTCGTGCAGG	PTGIR	ENSG00000160013	-0.4590415774357899	[303]	[158,162,196,191]	-7	hSpCas9	negative selection	6478456
46623995	46624018	19	+	27260156	CORL105	viability	GCGCGCATAGGCCACGAACACGG	PTGIR	ENSG00000160013	-0.29056326907153673	[584]	[731,455,592,471]	-5	hSpCas9	negative selection	6535446
46624061	46624084	19	+	27260156	CORL105	viability	TCCGGTCACCAGCACCGCGAAGG	PTGIR	ENSG00000160013	0.2565037029502983	[474]	[529,633,906,619]	5	hSpCas9	negative selection	6535447
46621377	46621400	19	+	27260156	CORL105	viability	CCCTCGCCCCAAGCCGACAAAGG	PTGIR	ENSG00000160013	0.8378358508712107	[122]	[248,280,202,286]	9	hSpCas9	negative selection	6535448
46621310	46621333	19	+	27260156	CORL105	viability	TGCTTTGGACGACGTTCCCACGG	PTGIR	ENSG00000160013	-0.48753793167343273	[1474]	[1203,1278,1336,1120]	-7	hSpCas9	negative selection	6599705
46624039	46624062	19	-	27260156	CORL105	viability	ACTGGCGGCCACCGACCTGCTGG	PTGIR	ENSG00000160013	0.061407904485401815	[383]	[502,437,412,514]	1	hSpCas9	negative selection	6599706
46624208	46624231	19	-	27260156	CORL105	viability	CTGGGATGGCGGATTCGTGCAGG	PTGIR	ENSG00000160013	0.05084918989055187	[303]	[482,343,341,305]	0	hSpCas9	negative selection	6599707
46623995	46624018	19	+	27260156	HS294T	viability	GCGCGCATAGGCCACGAACACGG	PTGIR	ENSG00000160013	0.6197415952526246	[584]	[385,344,273,386]	7	hSpCas9	negative selection	6656697
46624061	46624084	19	+	27260156	HS294T	viability	TCCGGTCACCAGCACCGCGAAGG	PTGIR	ENSG00000160013	0.775248998986891	[474]	[249,511,277,195]	8	hSpCas9	negative selection	6656698
46621377	46621400	19	+	27260156	HS294T	viability	CCCTCGCCCCAAGCCGACAAAGG	PTGIR	ENSG00000160013	0.78791485766764	[122]	[55,87,111,72]	8	hSpCas9	negative selection	6656699
46621310	46621333	19	+	27260156	HS294T	viability	TGCTTTGGACGACGTTCCCACGG	PTGIR	ENSG00000160013	-0.17127813456117935	[1474]	[359,555,477,669]	-2	hSpCas9	negative selection	6720956
46624039	46624062	19	-	27260156	HS294T	viability	ACTGGCGGCCACCGACCTGCTGG	PTGIR	ENSG00000160013	0.3521989064980894	[383]	[144,287,162,156]	5	hSpCas9	negative selection	6720957
46624208	46624231	19	-	27260156	HS294T	viability	CTGGGATGGCGGATTCGTGCAGG	PTGIR	ENSG00000160013	0.053370419243396916	[303]	[123,105,104,158]	0	hSpCas9	negative selection	6720958
46623995	46624018	19	+	27260156	HCC44	viability	GCGCGCATAGGCCACGAACACGG	PTGIR	ENSG00000160013	0.023218582265817633	[584]	[717,581,781,638]	0	hSpCas9	negative selection	6777948
46624061	46624084	19	+	27260156	HCC44	viability	TCCGGTCACCAGCACCGCGAAGG	PTGIR	ENSG00000160013	0.46893173121506626	[474]	[882,579,921,652]	7	hSpCas9	negative selection	6777949
46621377	46621400	19	+	27260156	HCC44	viability	CCCTCGCCCCAAGCCGACAAAGG	PTGIR	ENSG00000160013	0.7526433454398371	[122]	[387,226,133,185]	9	hSpCas9	negative selection	6777950
46621310	46621333	19	+	27260156	HCC44	viability	TGCTTTGGACGACGTTCCCACGG	PTGIR	ENSG00000160013	-0.24141900557957974	[1474]	[1260,1411,1856,1173]	-4	hSpCas9	negative selection	6842207
46624039	46624062	19	-	27260156	HCC44	viability	ACTGGCGGCCACCGACCTGCTGG	PTGIR	ENSG00000160013	0.16982659079908807	[383]	[562,340,478,589]	2	hSpCas9	negative selection	6842208
46624208	46624231	19	-	27260156	HCC44	viability	CTGGGATGGCGGATTCGTGCAGG	PTGIR	ENSG00000160013	0.13072045436796953	[303]	[414,240,372,491]	2	hSpCas9	negative selection	6842209
46623995	46624018	19	+	27260156	G402	viability	GCGCGCATAGGCCACGAACACGG	PTGIR	ENSG00000160013	0.2563995247340905	[584]	[1146,751,862,689]	3	hSpCas9	negative selection	6899199
46624061	46624084	19	+	27260156	G402	viability	TCCGGTCACCAGCACCGCGAAGG	PTGIR	ENSG00000160013	0.24637641789792059	[474]	[675,877,687,522]	3	hSpCas9	negative selection	6899200
46621377	46621400	19	+	27260156	G402	viability	CCCTCGCCCCAAGCCGACAAAGG	PTGIR	ENSG00000160013	0.7337104217682651	[122]	[244,442,177,146]	8	hSpCas9	negative selection	6899201
46621310	46621333	19	+	27260156	G402	viability	TGCTTTGGACGACGTTCCCACGG	PTGIR	ENSG00000160013	-0.5516216400748306	[1474]	[1307,2014,1065,605]	-6	hSpCas9	negative selection	6963458
46624039	46624062	19	-	27260156	G402	viability	ACTGGCGGCCACCGACCTGCTGG	PTGIR	ENSG00000160013	-0.24163350300201936	[383]	[229,407,497,422]	-3	hSpCas9	negative selection	6963459
46624208	46624231	19	-	27260156	G402	viability	CTGGGATGGCGGATTCGTGCAGG	PTGIR	ENSG00000160013	-0.3240188773727043	[303]	[350,368,237,240]	-4	hSpCas9	negative selection	6963460
46623995	46624018	19	+	27260156	L33	viability	GCGCGCATAGGCCACGAACACGG	PTGIR	ENSG00000160013	0.16572029838832747	[584]	[758,284,382,558]	3	hSpCas9	negative selection	7020450
46624061	46624084	19	+	27260156	L33	viability	TCCGGTCACCAGCACCGCGAAGG	PTGIR	ENSG00000160013	0.24302692428179568	[474]	[587,207,277,707]	5	hSpCas9	negative selection	7020451
46621377	46621400	19	+	27260156	L33	viability	CCCTCGCCCCAAGCCGACAAAGG	PTGIR	ENSG00000160013	0.9083717454052662	[122]	[206,108,106,279]	9	hSpCas9	negative selection	7020452
46621310	46621333	19	+	27260156	L33	viability	TGCTTTGGACGACGTTCCCACGG	PTGIR	ENSG00000160013	-0.11802732159282092	[1474]	[1392,544,638,1690]	-3	hSpCas9	negative selection	7084709
46624039	46624062	19	-	27260156	L33	viability	ACTGGCGGCCACCGACCTGCTGG	PTGIR	ENSG00000160013	0.30465439792249793	[383]	[488,267,266,329]	6	hSpCas9	negative selection	7084710
46624208	46624231	19	-	27260156	L33	viability	CTGGGATGGCGGATTCGTGCAGG	PTGIR	ENSG00000160013	-0.16671442811515058	[303]	[311,98,173,251]	-4	hSpCas9	negative selection	7084711
46623995	46624018	19	+	27260156	K562	viability	GCGCGCATAGGCCACGAACACGG	PTGIR	ENSG00000160013	-0.35430587031823974	[584]	[363,351,320,560]	-4	hSpCas9	negative selection	7141701
46624061	46624084	19	+	27260156	K562	viability	TCCGGTCACCAGCACCGCGAAGG	PTGIR	ENSG00000160013	-1.5453109914376553e-05	[474]	[193,695,480,320]	0	hSpCas9	negative selection	7141702
46621377	46621400	19	+	27260156	K562	viability	CCCTCGCCCCAAGCCGACAAAGG	PTGIR	ENSG00000160013	0.29280036098616335	[122]	[206,85,131,114]	3	hSpCas9	negative selection	7141703
46621310	46621333	19	+	27260156	K562	viability	TGCTTTGGACGACGTTCCCACGG	PTGIR	ENSG00000160013	-0.8969601363549378	[1474]	[868,736,683,551]	-7	hSpCas9	negative selection	7205960
46624039	46624062	19	-	27260156	K562	viability	ACTGGCGGCCACCGACCTGCTGG	PTGIR	ENSG00000160013	0.30107302564855737	[383]	[581,315,504,296]	4	hSpCas9	negative selection	7205961
46624208	46624231	19	-	27260156	K562	viability	CTGGGATGGCGGATTCGTGCAGG	PTGIR	ENSG00000160013	0.1576574706235092	[303]	[286,493,115,312]	2	hSpCas9	negative selection	7205962
46623995	46624018	19	+	27260156	HT29	viability	GCGCGCATAGGCCACGAACACGG	PTGIR	ENSG00000160013	-0.18221215951839975	[584]	[677,674,552,606]	-4	hSpCas9	negative selection	7262952
46624061	46624084	19	+	27260156	HT29	viability	TCCGGTCACCAGCACCGCGAAGG	PTGIR	ENSG00000160013	0.4576879432189111	[474]	[649,790,920,792]	8	hSpCas9	negative selection	7262953
46621377	46621400	19	+	27260156	HT29	viability	CCCTCGCCCCAAGCCGACAAAGG	PTGIR	ENSG00000160013	0.3999715454380244	[122]	[194,208,289,105]	7	hSpCas9	negative selection	7262954
46621310	46621333	19	+	27260156	HT29	viability	TGCTTTGGACGACGTTCCCACGG	PTGIR	ENSG00000160013	-0.8348962967562729	[1474]	[1102,847,920,1120]	-8	hSpCas9	negative selection	7327211
46624039	46624062	19	-	27260156	HT29	viability	ACTGGCGGCCACCGACCTGCTGG	PTGIR	ENSG00000160013	-0.06890422936078178	[383]	[528,386,539,335]	-1	hSpCas9	negative selection	7327212
46624208	46624231	19	-	27260156	HT29	viability	CTGGGATGGCGGATTCGTGCAGG	PTGIR	ENSG00000160013	-0.47703520542467737	[303]	[263,257,286,251]	-7	hSpCas9	negative selection	7327213
46623995	46624018	19	+	27260156	MHHES1	viability	GCGCGCATAGGCCACGAACACGG	PTGIR	ENSG00000160013	-0.2675318443279062	[584]	[537,588,492,556]	-5	hSpCas9	negative selection	7384203
46624061	46624084	19	+	27260156	MHHES1	viability	TCCGGTCACCAGCACCGCGAAGG	PTGIR	ENSG00000160013	0.26471527186660343	[474]	[744,849,595,444]	5	hSpCas9	negative selection	7384204
46621377	46621400	19	+	27260156	MHHES1	viability	CCCTCGCCCCAAGCCGACAAAGG	PTGIR	ENSG00000160013	0.6711505161941	[122]	[324,220,156,192]	9	hSpCas9	negative selection	7384205
46621310	46621333	19	+	27260156	MHHES1	viability	TGCTTTGGACGACGTTCCCACGG	PTGIR	ENSG00000160013	-0.2039790200051137	[1474]	[1850,1375,1229,1342]	-4	hSpCas9	negative selection	7448462
46624039	46624062	19	-	27260156	MHHES1	viability	ACTGGCGGCCACCGACCTGCTGG	PTGIR	ENSG00000160013	0.09913506023233143	[383]	[555,687,342,321]	1	hSpCas9	negative selection	7448463
46624208	46624231	19	-	27260156	MHHES1	viability	CTGGGATGGCGGATTCGTGCAGG	PTGIR	ENSG00000160013	-0.057266320448472796	[303]	[305,433,373,226]	-1	hSpCas9	negative selection	7448464
46623995	46624018	19	+	27260156	MEWO	viability	GCGCGCATAGGCCACGAACACGG	PTGIR	ENSG00000160013	-0.11667841934362486	[584]	[574,471,480]	-3	hSpCas9	negative selection	7505454
46624061	46624084	19	+	27260156	MEWO	viability	TCCGGTCACCAGCACCGCGAAGG	PTGIR	ENSG00000160013	-0.0343561692591582	[474]	[589,421,319]	0	hSpCas9	negative selection	7505455
46621377	46621400	19	+	27260156	MEWO	viability	CCCTCGCCCCAAGCCGACAAAGG	PTGIR	ENSG00000160013	0.8384240815575659	[122]	[326,150,162]	9	hSpCas9	negative selection	7505456
46621310	46621333	19	+	27260156	MEWO	viability	TGCTTTGGACGACGTTCCCACGG	PTGIR	ENSG00000160013	-0.290266137307281	[1474]	[1553,1039,873]	-6	hSpCas9	negative selection	7569713
46624039	46624062	19	-	27260156	MEWO	viability	ACTGGCGGCCACCGACCTGCTGG	PTGIR	ENSG00000160013	0.14070224420579408	[383]	[369,403,408]	3	hSpCas9	negative selection	7569714
46624208	46624231	19	-	27260156	MEWO	viability	CTGGGATGGCGGATTCGTGCAGG	PTGIR	ENSG00000160013	-0.1582536056067494	[303]	[298,271,201]	-3	hSpCas9	negative selection	7569715
46623995	46624018	19	+	27260156	LNCAPCLONEFGC	viability	GCGCGCATAGGCCACGAACACGG	PTGIR	ENSG00000160013	0.15691123019541392	[584]	[700,629,643,390]	2	hSpCas9	negative selection	7626705
46624061	46624084	19	+	27260156	LNCAPCLONEFGC	viability	TCCGGTCACCAGCACCGCGAAGG	PTGIR	ENSG00000160013	0.4714526770025495	[474]	[502,544,864,517]	7	hSpCas9	negative selection	7626706
46621377	46621400	19	+	27260156	LNCAPCLONEFGC	viability	CCCTCGCCCCAAGCCGACAAAGG	PTGIR	ENSG00000160013	0.9658086712284958	[122]	[208,232,274,160]	9	hSpCas9	negative selection	7626707
46621310	46621333	19	+	27260156	LNCAPCLONEFGC	viability	TGCTTTGGACGACGTTCCCACGG	PTGIR	ENSG00000160013	-0.29109634030859266	[1474]	[935,1025,1491,979]	-4	hSpCas9	negative selection	7690964
46624039	46624062	19	-	27260156	LNCAPCLONEFGC	viability	ACTGGCGGCCACCGACCTGCTGG	PTGIR	ENSG00000160013	0.2807032850695814	[383]	[410,425,496,366]	4	hSpCas9	negative selection	7690965
46624208	46624231	19	-	27260156	LNCAPCLONEFGC	viability	CTGGGATGGCGGATTCGTGCAGG	PTGIR	ENSG00000160013	-0.33255809498306477	[303]	[158,251,342,137]	-5	hSpCas9	negative selection	7690966
46623995	46624018	19	+	27260156	PANC0327	viability	GCGCGCATAGGCCACGAACACGG	PTGIR	ENSG00000160013	0.002532727747112551	[584]	[706,344,490,576]	0	hSpCas9	negative selection	7747956
46624061	46624084	19	+	27260156	PANC0327	viability	TCCGGTCACCAGCACCGCGAAGG	PTGIR	ENSG00000160013	0.5210916142796449	[474]	[943,410,273,844]	7	hSpCas9	negative selection	7747957
46621377	46621400	19	+	27260156	PANC0327	viability	CCCTCGCCCCAAGCCGACAAAGG	PTGIR	ENSG00000160013	-0.012969236959785135	[122]	[144,86,163,42]	0	hSpCas9	negative selection	7747958
46621310	46621333	19	+	27260156	PANC0327	viability	TGCTTTGGACGACGTTCCCACGG	PTGIR	ENSG00000160013	-0.8696895587236774	[1474]	[766,595,856,667]	-8	hSpCas9	negative selection	7812215
46624039	46624062	19	-	27260156	PANC0327	viability	ACTGGCGGCCACCGACCTGCTGG	PTGIR	ENSG00000160013	-0.1596608301029675	[383]	[355,255,337,281]	-2	hSpCas9	negative selection	7812216
46624208	46624231	19	-	27260156	PANC0327	viability	CTGGGATGGCGGATTCGTGCAGG	PTGIR	ENSG00000160013	0.11841668075620648	[303]	[363,207,175,440]	1	hSpCas9	negative selection	7812217
46623995	46624018	19	+	27260156	NCIH2009	viability	GCGCGCATAGGCCACGAACACGG	PTGIR	ENSG00000160013	0.1041398528861831	[584]	[1174,914,601]	1	hSpCas9	negative selection	7869207
46624061	46624084	19	+	27260156	NCIH2009	viability	TCCGGTCACCAGCACCGCGAAGG	PTGIR	ENSG00000160013	0.9773947177700426	[474]	[1681,973,1341]	9	hSpCas9	negative selection	7869208
46621377	46621400	19	+	27260156	NCIH2009	viability	CCCTCGCCCCAAGCCGACAAAGG	PTGIR	ENSG00000160013	1.2917154759887324	[122]	[352,203,694]	9	hSpCas9	negative selection	7869209
46621310	46621333	19	+	27260156	NCIH2009	viability	TGCTTTGGACGACGTTCCCACGG	PTGIR	ENSG00000160013	-0.3225695583866428	[1474]	[1968,1559,1476]	-4	hSpCas9	negative selection	7933466
46624039	46624062	19	-	27260156	NCIH2009	viability	ACTGGCGGCCACCGACCTGCTGG	PTGIR	ENSG00000160013	0.29084904549560847	[383]	[794,673,525]	4	hSpCas9	negative selection	7933467
46624208	46624231	19	-	27260156	NCIH2009	viability	CTGGGATGGCGGATTCGTGCAGG	PTGIR	ENSG00000160013	0.12105622637127766	[303]	[741,258,442]	1	hSpCas9	negative selection	7933468
46623995	46624018	19	+	27260156	NCIH1373	viability	GCGCGCATAGGCCACGAACACGG	PTGIR	ENSG00000160013	0.03389119303859339	[584]	[667,521,840,173]	0	hSpCas9	negative selection	7990458
46624061	46624084	19	+	27260156	NCIH1373	viability	TCCGGTCACCAGCACCGCGAAGG	PTGIR	ENSG00000160013	-0.16015685384534303	[474]	[554,339,543,128]	-1	hSpCas9	negative selection	7990459
46621377	46621400	19	+	27260156	NCIH1373	viability	CCCTCGCCCCAAGCCGACAAAGG	PTGIR	ENSG00000160013	0.18374957219131072	[122]	[281,89,103,46]	1	hSpCas9	negative selection	7990460
46621310	46621333	19	+	27260156	NCIH1373	viability	TGCTTTGGACGACGTTCCCACGG	PTGIR	ENSG00000160013	-0.6291760281063052	[1474]	[748,1121,1356,255]	-6	hSpCas9	negative selection	8054717
46624039	46624062	19	-	27260156	NCIH1373	viability	ACTGGCGGCCACCGACCTGCTGG	PTGIR	ENSG00000160013	0.07670994360455075	[383]	[676,477,276,108]	0	hSpCas9	negative selection	8054718
46624208	46624231	19	-	27260156	NCIH1373	viability	CTGGGATGGCGGATTCGTGCAGG	PTGIR	ENSG00000160013	-0.011610578600577681	[303]	[586,295,157,93]	0	hSpCas9	negative selection	8054719
46623995	46624018	19	+	27260156	PATU8902	viability	GCGCGCATAGGCCACGAACACGG	PTGIR	ENSG00000160013	-0.0242710820550876	[584]	[552,1145,617,950]	0	hSpCas9	negative selection	8111709
46624061	46624084	19	+	27260156	PATU8902	viability	TCCGGTCACCAGCACCGCGAAGG	PTGIR	ENSG00000160013	-0.11351788802128952	[474]	[655,714,478,626]	-1	hSpCas9	negative selection	8111710
46621377	46621400	19	+	27260156	PATU8902	viability	CCCTCGCCCCAAGCCGACAAAGG	PTGIR	ENSG00000160013	0.5798277611978806	[122]	[462,68,61,504]	6	hSpCas9	negative selection	8111711
46621310	46621333	19	+	27260156	PATU8902	viability	TGCTTTGGACGACGTTCCCACGG	PTGIR	ENSG00000160013	-0.8011832911236048	[1474]	[979,1507,849,1494]	-6	hSpCas9	negative selection	8175968
46624039	46624062	19	-	27260156	PATU8902	viability	ACTGGCGGCCACCGACCTGCTGG	PTGIR	ENSG00000160013	0.044372520801220006	[383]	[329,737,413,786]	0	hSpCas9	negative selection	8175969
46624208	46624231	19	-	27260156	PATU8902	viability	CTGGGATGGCGGATTCGTGCAGG	PTGIR	ENSG00000160013	0.4036355324399185	[303]	[709,331,338,956]	4	hSpCas9	negative selection	8175970
46623995	46624018	19	+	27260156	PANC1	viability	GCGCGCATAGGCCACGAACACGG	PTGIR	ENSG00000160013	0.08085662317936032	[584]	[280,571,784,499]	1	hSpCas9	negative selection	8232960
46624061	46624084	19	+	27260156	PANC1	viability	TCCGGTCACCAGCACCGCGAAGG	PTGIR	ENSG00000160013	0.3035466765887347	[474]	[518,668,412,446]	5	hSpCas9	negative selection	8232961
46621377	46621400	19	+	27260156	PANC1	viability	CCCTCGCCCCAAGCCGACAAAGG	PTGIR	ENSG00000160013	0.8727751163739514	[122]	[261,153,252,106]	9	hSpCas9	negative selection	8232962
46621310	46621333	19	+	27260156	PANC1	viability	TGCTTTGGACGACGTTCCCACGG	PTGIR	ENSG00000160013	0.1362485849498951	[1474]	[1359,1412,1346,1424]	2	hSpCas9	negative selection	8297219
46624039	46624062	19	-	27260156	PANC1	viability	ACTGGCGGCCACCGACCTGCTGG	PTGIR	ENSG00000160013	0.22198306153313968	[383]	[538,472,372,193]	3	hSpCas9	negative selection	8297220
46624208	46624231	19	-	27260156	PANC1	viability	CTGGGATGGCGGATTCGTGCAGG	PTGIR	ENSG00000160013	-0.08856723077347306	[303]	[306,277,180,220]	-1	hSpCas9	negative selection	8297221
46623995	46624018	19	+	27260156	PANC0813	viability	GCGCGCATAGGCCACGAACACGG	PTGIR	ENSG00000160013	0.05033493654521859	[584]	[774,841,676,564]	0	hSpCas9	negative selection	8354211
46624061	46624084	19	+	27260156	PANC0813	viability	TCCGGTCACCAGCACCGCGAAGG	PTGIR	ENSG00000160013	0.39183878284733326	[474]	[714,743,622,836]	6	hSpCas9	negative selection	8354212
46621377	46621400	19	+	27260156	PANC0813	viability	CCCTCGCCCCAAGCCGACAAAGG	PTGIR	ENSG00000160013	0.9008687879700501	[122]	[460,285,294,65]	9	hSpCas9	negative selection	8354213
46621310	46621333	19	+	27260156	PANC0813	viability	TGCTTTGGACGACGTTCCCACGG	PTGIR	ENSG00000160013	-0.30123689823982125	[1474]	[1248,1772,1088,1489]	-5	hSpCas9	negative selection	8418470
46624039	46624062	19	-	27260156	PANC0813	viability	ACTGGCGGCCACCGACCTGCTGG	PTGIR	ENSG00000160013	0.09493435655613985	[383]	[526,417,357,618]	1	hSpCas9	negative selection	8418471
46624208	46624231	19	-	27260156	PANC0813	viability	CTGGGATGGCGGATTCGTGCAGG	PTGIR	ENSG00000160013	-0.2316659552390925	[303]	[358,383,252,228]	-4	hSpCas9	negative selection	8418472
46623995	46624018	19	+	27260156	RDES	viability	GCGCGCATAGGCCACGAACACGG	PTGIR	ENSG00000160013	-0.20824207371919554	[584]	[517,529,610,687]	-4	hSpCas9	negative selection	8475462
46624061	46624084	19	+	27260156	RDES	viability	TCCGGTCACCAGCACCGCGAAGG	PTGIR	ENSG00000160013	0.035576675694409504	[474]	[464,564,638,578]	0	hSpCas9	negative selection	8475463
46621377	46621400	19	+	27260156	RDES	viability	CCCTCGCCCCAAGCCGACAAAGG	PTGIR	ENSG00000160013	0.6817865340104898	[122]	[152,203,229,351]	9	hSpCas9	negative selection	8475464
46621310	46621333	19	+	27260156	RDES	viability	TGCTTTGGACGACGTTCCCACGG	PTGIR	ENSG00000160013	-0.4130443512812696	[1474]	[961,1178,1547,1489]	-6	hSpCas9	negative selection	8539721
46624039	46624062	19	-	27260156	RDES	viability	ACTGGCGGCCACCGACCTGCTGG	PTGIR	ENSG00000160013	0.09491768463930478	[383]	[492,426,439,514]	1	hSpCas9	negative selection	8539722
46624208	46624231	19	-	27260156	RDES	viability	CTGGGATGGCGGATTCGTGCAGG	PTGIR	ENSG00000160013	-0.23959243813652686	[303]	[252,329,338,253]	-4	hSpCas9	negative selection	8539723
46623995	46624018	19	+	27260156	PC3	viability	GCGCGCATAGGCCACGAACACGG	PTGIR	ENSG00000160013	-0.17015933649032086	[584]	[264,485,967,603]	-4	hSpCas9	negative selection	8596713
46624061	46624084	19	+	27260156	PC3	viability	TCCGGTCACCAGCACCGCGAAGG	PTGIR	ENSG00000160013	0.5388005444119766	[474]	[315,773,1389,649]	9	hSpCas9	negative selection	8596714
46621377	46621400	19	+	27260156	PC3	viability	CCCTCGCCCCAAGCCGACAAAGG	PTGIR	ENSG00000160013	0.780096867634746	[122]	[164,161,369,204]	9	hSpCas9	negative selection	8596715
46621310	46621333	19	+	27260156	PC3	viability	TGCTTTGGACGACGTTCCCACGG	PTGIR	ENSG00000160013	-0.28406267364644355	[1474]	[871,987,2372,1072]	-6	hSpCas9	negative selection	8660972
46624039	46624062	19	-	27260156	PC3	viability	ACTGGCGGCCACCGACCTGCTGG	PTGIR	ENSG00000160013	0.07077873424957215	[383]	[304,396,574,393]	1	hSpCas9	negative selection	8660973
46624208	46624231	19	-	27260156	PC3	viability	CTGGGATGGCGGATTCGTGCAGG	PTGIR	ENSG00000160013	-0.3872840884446216	[303]	[169,277,253,230]	-7	hSpCas9	negative selection	8660974
46623995	46624018	19	+	27260156	PATU8988T	viability	GCGCGCATAGGCCACGAACACGG	PTGIR	ENSG00000160013	-0.4412334717158498	[584]	[313,363,351,649]	-6	hSpCas9	negative selection	8717964
46624061	46624084	19	+	27260156	PATU8988T	viability	TCCGGTCACCAGCACCGCGAAGG	PTGIR	ENSG00000160013	0.3329858089531832	[474]	[550,503,624,628]	6	hSpCas9	negative selection	8717965
46621377	46621400	19	+	27260156	PATU8988T	viability	CCCTCGCCCCAAGCCGACAAAGG	PTGIR	ENSG00000160013	0.10851667535830489	[122]	[146,104,113,145]	1	hSpCas9	negative selection	8717966
46621310	46621333	19	+	27260156	PATU8988T	viability	TGCTTTGGACGACGTTCCCACGG	PTGIR	ENSG00000160013	-0.8443676415810214	[1474]	[995,787,455,951]	-8	hSpCas9	negative selection	8782223
46624039	46624062	19	-	27260156	PATU8988T	viability	ACTGGCGGCCACCGACCTGCTGG	PTGIR	ENSG00000160013	0.024693627805148055	[383]	[547,383,318,249]	0	hSpCas9	negative selection	8782224
46624208	46624231	19	-	27260156	PATU8988T	viability	CTGGGATGGCGGATTCGTGCAGG	PTGIR	ENSG00000160013	-0.12511597880536673	[303]	[57,289,318,423]	-2	hSpCas9	negative selection	8782225
46623995	46624018	19	+	27260156	T47D	viability	GCGCGCATAGGCCACGAACACGG	PTGIR	ENSG00000160013	-0.09299277087622748	[584]	[670,544,624,725]	-2	hSpCas9	negative selection	8839215
46624061	46624084	19	+	27260156	T47D	viability	TCCGGTCACCAGCACCGCGAAGG	PTGIR	ENSG00000160013	0.08366384284668768	[474]	[581,496,698,572]	1	hSpCas9	negative selection	8839216
46621377	46621400	19	+	27260156	T47D	viability	CCCTCGCCCCAAGCCGACAAAGG	PTGIR	ENSG00000160013	0.3438465261944059	[122]	[232,141,177,177]	7	hSpCas9	negative selection	8839217
46621310	46621333	19	+	27260156	T47D	viability	TGCTTTGGACGACGTTCCCACGG	PTGIR	ENSG00000160013	-0.5163397008776305	[1474]	[1094,1202,1219,1288]	-8	hSpCas9	negative selection	8903474
46624039	46624062	19	-	27260156	T47D	viability	ACTGGCGGCCACCGACCTGCTGG	PTGIR	ENSG00000160013	-0.04163765881183168	[383]	[402,476,394,460]	-1	hSpCas9	negative selection	8903475
46624208	46624231	19	-	27260156	T47D	viability	CTGGGATGGCGGATTCGTGCAGG	PTGIR	ENSG00000160013	-0.03250228185296822	[303]	[325,304,398,357]	0	hSpCas9	negative selection	8903476
46623995	46624018	19	+	27260156	SU8686	viability	GCGCGCATAGGCCACGAACACGG	PTGIR	ENSG00000160013	0.14406810076443743	[584]	[589,557,613,845]	2	hSpCas9	negative selection	8960466
46624061	46624084	19	+	27260156	SU8686	viability	TCCGGTCACCAGCACCGCGAAGG	PTGIR	ENSG00000160013	0.25326261565021474	[474]	[410,495,708,672]	4	hSpCas9	negative selection	8960467
46621377	46621400	19	+	27260156	SU8686	viability	CCCTCGCCCCAAGCCGACAAAGG	PTGIR	ENSG00000160013	0.9202586768180008	[122]	[229,194,154,365]	9	hSpCas9	negative selection	8960468
46621310	46621333	19	+	27260156	SU8686	viability	TGCTTTGGACGACGTTCCCACGG	PTGIR	ENSG00000160013	-0.1460680341618248	[1474]	[1265,1014,1532,1551]	-3	hSpCas9	negative selection	9024725
46624039	46624062	19	-	27260156	SU8686	viability	ACTGGCGGCCACCGACCTGCTGG	PTGIR	ENSG00000160013	0.10186987912057752	[383]	[415,404,273,555]	1	hSpCas9	negative selection	9024726
46624208	46624231	19	-	27260156	SU8686	viability	CTGGGATGGCGGATTCGTGCAGG	PTGIR	ENSG00000160013	-0.10901431077387125	[303]	[304,215,279,327]	-2	hSpCas9	negative selection	9024727
46623995	46624018	19	+	27260156	SKES1	viability	GCGCGCATAGGCCACGAACACGG	PTGIR	ENSG00000160013	-0.18056870753607962	[584]	[499,625,595,360]	-4	hSpCas9	negative selection	9081717
46624061	46624084	19	+	27260156	SKES1	viability	TCCGGTCACCAGCACCGCGAAGG	PTGIR	ENSG00000160013	0.30166591392097597	[474]	[694,807,411,472]	6	hSpCas9	negative selection	9081718
46621377	46621400	19	+	27260156	SKES1	viability	CCCTCGCCCCAAGCCGACAAAGG	PTGIR	ENSG00000160013	0.5207473447627728	[122]	[281,218,172,61]	9	hSpCas9	negative selection	9081719
46621310	46621333	19	+	27260156	SKES1	viability	TGCTTTGGACGACGTTCCCACGG	PTGIR	ENSG00000160013	-0.4738120179358305	[1474]	[1401,1108,914,877]	-8	hSpCas9	negative selection	9145976
46624039	46624062	19	-	27260156	SKES1	viability	ACTGGCGGCCACCGACCTGCTGG	PTGIR	ENSG00000160013	0.36616832202482064	[383]	[442,515,667,352]	7	hSpCas9	negative selection	9145977
46624208	46624231	19	-	27260156	SKES1	viability	CTGGGATGGCGGATTCGTGCAGG	PTGIR	ENSG00000160013	-0.2606471287265797	[303]	[246,305,241,223]	-5	hSpCas9	negative selection	9145978
46623995	46624018	19	+	27260156	TOV112D	viability	GCGCGCATAGGCCACGAACACGG	PTGIR	ENSG00000160013	-0.23723864956121316	[584]	[250,607,419,708]	-4	hSpCas9	negative selection	9202968
46624061	46624084	19	+	27260156	TOV112D	viability	TCCGGTCACCAGCACCGCGAAGG	PTGIR	ENSG00000160013	0.3374720039326642	[474]	[687,676,700,369]	6	hSpCas9	negative selection	9202969
46621377	46621400	19	+	27260156	TOV112D	viability	CCCTCGCCCCAAGCCGACAAAGG	PTGIR	ENSG00000160013	0.28276289453604986	[122]	[191,85,193,115]	5	hSpCas9	negative selection	9202970
46621310	46621333	19	+	27260156	TOV112D	viability	TGCTTTGGACGACGTTCCCACGG	PTGIR	ENSG00000160013	-0.5044827455846013	[1474]	[1356,1121,829,904]	-7	hSpCas9	negative selection	9267227
46624039	46624062	19	-	27260156	TOV112D	viability	ACTGGCGGCCACCGACCTGCTGG	PTGIR	ENSG00000160013	0.06201006171408796	[383]	[193,506,446,463]	1	hSpCas9	negative selection	9267228
46624208	46624231	19	-	27260156	TOV112D	viability	CTGGGATGGCGGATTCGTGCAGG	PTGIR	ENSG00000160013	-0.5456113039619186	[303]	[286,216,140,197]	-8	hSpCas9	negative selection	9267229
46623995	46624018	19	+	27260156	TC71	viability	GCGCGCATAGGCCACGAACACGG	PTGIR	ENSG00000160013	-0.21543670853428737	[584]	[580,631,486,455]	-5	hSpCas9	negative selection	9324219
46624061	46624084	19	+	27260156	TC71	viability	TCCGGTCACCAGCACCGCGAAGG	PTGIR	ENSG00000160013	0.2314464713571112	[474]	[560,649,556,626]	6	hSpCas9	negative selection	9324220
46621377	46621400	19	+	27260156	TC71	viability	CCCTCGCCCCAAGCCGACAAAGG	PTGIR	ENSG00000160013	0.8120805104377702	[122]	[245,154,257,267]	9	hSpCas9	negative selection	9324221
46621310	46621333	19	+	27260156	TC71	viability	TGCTTTGGACGACGTTCCCACGG	PTGIR	ENSG00000160013	-0.31721741126597314	[1474]	[1091,1357,1397,1224]	-7	hSpCas9	negative selection	9388478
46624039	46624062	19	-	27260156	TC71	viability	ACTGGCGGCCACCGACCTGCTGG	PTGIR	ENSG00000160013	0.1710436074110045	[383]	[374,437,505,539]	4	hSpCas9	negative selection	9388479
46624208	46624231	19	-	27260156	TC71	viability	CTGGGATGGCGGATTCGTGCAGG	PTGIR	ENSG00000160013	-0.022984318680047022	[303]	[265,367,336,311]	0	hSpCas9	negative selection	9388480
46623995	46624018	19	+	27260156	TC32	viability	GCGCGCATAGGCCACGAACACGG	PTGIR	ENSG00000160013	0.09225351651168656	[584]	[372,759,720,424]	1	hSpCas9	negative selection	9445470
46624061	46624084	19	+	27260156	TC32	viability	TCCGGTCACCAGCACCGCGAAGG	PTGIR	ENSG00000160013	0.23240774402279152	[474]	[571,352,620,599]	4	hSpCas9	negative selection	9445471
46621377	46621400	19	+	27260156	TC32	viability	CCCTCGCCCCAAGCCGACAAAGG	PTGIR	ENSG00000160013	0.7687571079474536	[122]	[150,128,288,258]	9	hSpCas9	negative selection	9445472
46621310	46621333	19	+	27260156	TC32	viability	TGCTTTGGACGACGTTCCCACGG	PTGIR	ENSG00000160013	-0.6013981503316681	[1474]	[844,668,1296,959]	-8	hSpCas9	negative selection	9509729
46624039	46624062	19	-	27260156	TC32	viability	ACTGGCGGCCACCGACCTGCTGG	PTGIR	ENSG00000160013	0.15287247834596698	[383]	[370,246,570,489]	3	hSpCas9	negative selection	9509730
46624208	46624231	19	-	27260156	TC32	viability	CTGGGATGGCGGATTCGTGCAGG	PTGIR	ENSG00000160013	-0.0503917184535041	[303]	[298,195,283,339]	-1	hSpCas9	negative selection	9509731
46621344	46621367	19	+	27869803	HPAFII	viability after 27 days	GACTGCTGTGTGGGAGGCAAGGG	PTGIR	ENSG00000160013	-1.3510378466765451	[175]	[56,18,NaN]	-7	hSpCas9	negative selection	9568665
46621410	46621433	19	-	27869803	HPAFII	viability after 27 days	TCTGCTCCTGTGGGAAAGGAGGG	PTGIR	ENSG00000160013	0.5787217026873244	[203]	[193,131,NaN]	5	hSpCas9	negative selection	9568666
46623770	46623793	19	+	27869803	HPAFII	viability after 27 days	CGCGCAGAAGAGGACGCAGAAGG	PTGIR	ENSG00000160013	-0.45863486935025444	[436]	[212,128,NaN]	-3	hSpCas9	negative selection	9568667
46623934	46623957	19	+	27869803	HPAFII	viability after 27 days	CGAAGGCGAAGGCATCGCACAGG	PTGIR	ENSG00000160013	-0.050482553665705365	[355]	[249,122,NaN]	0	hSpCas9	negative selection	9568668
46623940	46623963	19	+	27869803	HPAFII	viability after 27 days	CGAAGGCATCGCACAGGGCGGGG	PTGIR	ENSG00000160013	0.33261725479195037	[328]	[321,130,NaN]	2	hSpCas9	negative selection	9568669
46623995	46624018	19	+	27869803	HPAFII	viability after 27 days	GCGCGCATAGGCCACGAACACGG	PTGIR	ENSG00000160013	0.015050972169543098	[1004]	[588,487,NaN]	0	hSpCas9	negative selection	9568670
46621344	46621367	19	+	27869803	HPAFII	viability after 15 days	GACTGCTGTGTGGGAGGCAAGGG	PTGIR	ENSG00000160013	-0.33440030238475227	[175]	[178,131,NaN]	-4	hSpCas9	negative selection	9651114
46621410	46621433	19	-	27869803	HPAFII	viability after 15 days	TCTGCTCCTGTGGGAAAGGAGGG	PTGIR	ENSG00000160013	0.4640883306664874	[203]	[508,173,NaN]	5	hSpCas9	negative selection	9651115
46623770	46623793	19	+	27869803	HPAFII	viability after 15 days	CGCGCAGAAGAGGACGCAGAAGG	PTGIR	ENSG00000160013	-0.2348738901411952	[436]	[699,211,NaN]	-3	hSpCas9	negative selection	9651116
46623934	46623957	19	+	27869803	HPAFII	viability after 15 days	CGAAGGCGAAGGCATCGCACAGG	PTGIR	ENSG00000160013	-0.29887957428960177	[355]	[265,338,NaN]	-3	hSpCas9	negative selection	9651117
46623940	46623963	19	+	27869803	HPAFII	viability after 15 days	CGAAGGCATCGCACAGGGCGGGG	PTGIR	ENSG00000160013	0.8643693664717673	[328]	[1017,410,NaN]	8	hSpCas9	negative selection	9651118
46623995	46624018	19	+	27869803	HPAFII	viability after 15 days	GCGCGCATAGGCCACGAACACGG	PTGIR	ENSG00000160013	0.21784119724173934	[1004]	[1450,1134,NaN]	2	hSpCas9	negative selection	9651119
46621344	46621367	19	+	27869803	ASPC1	viability after 36 days	GACTGCTGTGTGGGAGGCAAGGG	PTGIR	ENSG00000160013	-1.9038420335576256	[580]	[21,90,46]	-9	hSpCas9	negative selection	9733563
46621410	46621433	19	-	27869803	ASPC1	viability after 36 days	TCTGCTCCTGTGGGAAAGGAGGG	PTGIR	ENSG00000160013	-0.4036876599569051	[676]	[175,254,117]	-4	hSpCas9	negative selection	9733564
46623770	46623793	19	+	27869803	ASPC1	viability after 36 days	CGCGCAGAAGAGGACGCAGAAGG	PTGIR	ENSG00000160013	0.016525817737269688	[1002]	[460,321,300]	0	hSpCas9	negative selection	9733565
46623934	46623957	19	+	27869803	ASPC1	viability after 36 days	CGAAGGCGAAGGCATCGCACAGG	PTGIR	ENSG00000160013	0.3183877887062749	[817]	[533,304,267]	3	hSpCas9	negative selection	9733566
46623940	46623963	19	+	27869803	ASPC1	viability after 36 days	CGAAGGCATCGCACAGGGCGGGG	PTGIR	ENSG00000160013	0.2405096229625282	[951]	[594,527,138]	2	hSpCas9	negative selection	9733567
46623995	46624018	19	+	27869803	ASPC1	viability after 36 days	GCGCGCATAGGCCACGAACACGG	PTGIR	ENSG00000160013	0.04160131800923095	[2132]	[695,872,722]	0	hSpCas9	negative selection	9733568
46621344	46621367	19	+	27869803	PATU8988S	viability after 35 days	GACTGCTGTGTGGGAGGCAAGGG	PTGIR	ENSG00000160013	-0.4896961784758407	[449]	[160,96,NaN]	-5	hSpCas9	negative selection	9816012
46621410	46621433	19	-	27869803	PATU8988S	viability after 35 days	TCTGCTCCTGTGGGAAAGGAGGG	PTGIR	ENSG00000160013	-0.2208300079523349	[463]	[95,224,NaN]	-2	hSpCas9	negative selection	9816013
46623770	46623793	19	+	27869803	PATU8988S	viability after 35 days	CGCGCAGAAGAGGACGCAGAAGG	PTGIR	ENSG00000160013	-0.2153819968385677	[695]	[214,267,NaN]	-2	hSpCas9	negative selection	9816014
46623934	46623957	19	+	27869803	PATU8988S	viability after 35 days	CGAAGGCGAAGGCATCGCACAGG	PTGIR	ENSG00000160013	-0.14967964032870193	[602]	[185,251,NaN]	-1	hSpCas9	negative selection	9816015
46623940	46623963	19	+	27869803	PATU8988S	viability after 35 days	CGAAGGCATCGCACAGGGCGGGG	PTGIR	ENSG00000160013	-0.15026941528992105	[757]	[312,236,NaN]	-1	hSpCas9	negative selection	9816016
46623995	46624018	19	+	27869803	PATU8988S	viability after 35 days	GCGCGCATAGGCCACGAACACGG	PTGIR	ENSG00000160013	0.39523437143509543	[2166]	[1066,1228,NaN]	4	hSpCas9	negative selection	9816017
46621344	46621367	19	+	27869803	PATU8988S	viability after 31 days	GACTGCTGTGTGGGAGGCAAGGG	PTGIR	ENSG00000160013	-0.36168088951371513	[449]	[169,100,NaN]	-4	hSpCas9	negative selection	9898461
46621410	46621433	19	-	27869803	PATU8988S	viability after 31 days	TCTGCTCCTGTGGGAAAGGAGGG	PTGIR	ENSG00000160013	-0.25549493185430416	[463]	[99,224,NaN]	-3	hSpCas9	negative selection	9898462
46623770	46623793	19	+	27869803	PATU8988S	viability after 31 days	CGCGCAGAAGAGGACGCAGAAGG	PTGIR	ENSG00000160013	-0.7561741447113439	[695]	[129,207,NaN]	-7	hSpCas9	negative selection	9898463
46623934	46623957	19	+	27869803	PATU8988S	viability after 31 days	CGAAGGCGAAGGCATCGCACAGG	PTGIR	ENSG00000160013	-0.14409644743082273	[602]	[155,295,NaN]	-2	hSpCas9	negative selection	9898464
46623940	46623963	19	+	27869803	PATU8988S	viability after 31 days	CGAAGGCATCGCACAGGGCGGGG	PTGIR	ENSG00000160013	0.20496326100875994	[757]	[288,423,NaN]	2	hSpCas9	negative selection	9898465
46623995	46624018	19	+	27869803	PATU8988S	viability after 31 days	GCGCGCATAGGCCACGAACACGG	PTGIR	ENSG00000160013	0.3380644047699457	[2166]	[921,1308,NaN]	4	hSpCas9	negative selection	9898466
46621344	46621367	19	+	27869803	HPAFII	viability after 35 days	GACTGCTGTGTGGGAGGCAAGGG	PTGIR	ENSG00000160013	-1.1591262690365056	[175]	[69,5,NaN]	-6	hSpCas9	negative selection	9980910
46621410	46621433	19	-	27869803	HPAFII	viability after 35 days	TCTGCTCCTGTGGGAAAGGAGGG	PTGIR	ENSG00000160013	1.1933690192128985	[203]	[230,241,NaN]	7	hSpCas9	negative selection	9980911
46623770	46623793	19	+	27869803	HPAFII	viability after 35 days	CGCGCAGAAGAGGACGCAGAAGG	PTGIR	ENSG00000160013	-0.4121646614487495	[436]	[201,125,NaN]	-3	hSpCas9	negative selection	9980912
46623934	46623957	19	+	27869803	HPAFII	viability after 35 days	CGAAGGCGAAGGCATCGCACAGG	PTGIR	ENSG00000160013	-1.3861951775824268	[355]	[83,51,NaN]	-6	hSpCas9	negative selection	9980913
46623940	46623963	19	+	27869803	HPAFII	viability after 35 days	CGAAGGCATCGCACAGGGCGGGG	PTGIR	ENSG00000160013	0.15201933188632533	[328]	[193,174,NaN]	0	hSpCas9	negative selection	9980914
46623995	46624018	19	+	27869803	HPAFII	viability after 35 days	GCGCGCATAGGCCACGAACACGG	PTGIR	ENSG00000160013	0.24937218150906837	[1004]	[632,572,NaN]	1	hSpCas9	negative selection	9980915
46621344	46621367	19	+	27869803	HPAFII	viability after 31 days	GACTGCTGTGTGGGAGGCAAGGG	PTGIR	ENSG00000160013	-1.0494950923980602	[175]	[74,17,NaN]	-6	hSpCas9	negative selection	10063359
46621410	46621433	19	-	27869803	HPAFII	viability after 31 days	TCTGCTCCTGTGGGAAAGGAGGG	PTGIR	ENSG00000160013	0.9668278903624907	[203]	[240,204,NaN]	7	hSpCas9	negative selection	10063360
46623770	46623793	19	+	27869803	HPAFII	viability after 31 days	CGCGCAGAAGAGGACGCAGAAGG	PTGIR	ENSG00000160013	-0.29482896446198126	[436]	[253,140,NaN]	-2	hSpCas9	negative selection	10063361
46623934	46623957	19	+	27869803	HPAFII	viability after 31 days	CGAAGGCGAAGGCATCGCACAGG	PTGIR	ENSG00000160013	-1.2086873789019887	[355]	[73,99,NaN]	-6	hSpCas9	negative selection	10063362
46623940	46623963	19	+	27869803	HPAFII	viability after 31 days	CGAAGGCATCGCACAGGGCGGGG	PTGIR	ENSG00000160013	0.015674333396194617	[328]	[245,121,NaN]	0	hSpCas9	negative selection	10063363
46623995	46624018	19	+	27869803	HPAFII	viability after 31 days	GCGCGCATAGGCCACGAACACGG	PTGIR	ENSG00000160013	-0.011301190543517414	[1004]	[606,507,NaN]	0	hSpCas9	negative selection	10063364
46623838	46623861	19	+	28162770	P31FUJ	viability	GCTGCGCGTAGAGGTAGGGGTGG	PTGIR	ENSG00000160013	-0.10432764646556952	[203]	[222]	-1	hSpCas9	negative selection	10219547
46624031	46624054	19	+	28162770	P31FUJ	viability	GCTGGTGCCCAGCAGGTCGGTGG	PTGIR	ENSG00000160013	0.1140637922228859	[194]	[247]	1	hSpCas9	negative selection	10219548
46623709	46623732	19	+	28162770	P31FUJ	viability	GGAGGAAGCACCAGCTGCCGGGG	PTGIR	ENSG00000160013	-0.5282580879405498	[134]	[109]	-4	hSpCas9	negative selection	10219549
46624061	46624084	19	+	28162770	P31FUJ	viability	TCCGGTCACCAGCACCGCGAAGG	PTGIR	ENSG00000160013	0.5157657012978196	[321]	[540]	6	hSpCas9	negative selection	10219550
46623923	46623946	19	+	28162770	P31FUJ	viability	GAAGGTCATGGCGAAGGCGAAGG	PTGIR	ENSG00000160013	-0.36755161652761614	[156]	[142]	-3	hSpCas9	negative selection	10219551
46623604	46623627	19	+	28162770	P31FUJ	viability	GGGTGACCGAGCCGTTGCAGAGG	PTGIR	ENSG00000160013	0.4958957737682268	[34]	[57]	5	hSpCas9	negative selection	10219552
46623577	46623600	19	+	28162770	P31FUJ	viability	GCTGGCGGTACATGCGGCAGAGG	PTGIR	ENSG00000160013	-0.10419192939854771	[428]	[468]	-1	hSpCas9	negative selection	10219553
46623544	46623567	19	+	28162770	P31FUJ	viability	GCCGTGGACCCAGAGAGCCCTGG	PTGIR	ENSG00000160013	-2.431582068528876	[201]	[43]	-8	hSpCas9	negative selection	10219554
46623520	46623543	19	-	28162770	P31FUJ	viability	GCGCACCGGAGAGGACGAGGTGG	PTGIR	ENSG00000160013	-0.10351918746941191	[31]	[34]	-1	hSpCas9	negative selection	10219555
46624190	46624213	19	-	28162770	P31FUJ	viability	GCAGGAACCTCACCTACGTGCGG	PTGIR	ENSG00000160013	-0.14757890454534883	[492]	[522]	-1	hSpCas9	negative selection	10219556
46623838	46623861	19	+	28162770	TF1	viability	GCTGCGCGTAGAGGTAGGGGTGG	PTGIR	ENSG00000160013	NaN	[NaN]	[123]	1	hSpCas9	negative selection	10388913
46624031	46624054	19	+	28162770	TF1	viability	GCTGGTGCCCAGCAGGTCGGTGG	PTGIR	ENSG00000160013	NaN	[NaN]	[103]	1	hSpCas9	negative selection	10388914
46623709	46623732	19	+	28162770	TF1	viability	GGAGGAAGCACCAGCTGCCGGGG	PTGIR	ENSG00000160013	NaN	[NaN]	[45]	1	hSpCas9	negative selection	10388915
46624061	46624084	19	+	28162770	TF1	viability	TCCGGTCACCAGCACCGCGAAGG	PTGIR	ENSG00000160013	NaN	[NaN]	[296]	1	hSpCas9	negative selection	10388916
46623923	46623946	19	+	28162770	TF1	viability	GAAGGTCATGGCGAAGGCGAAGG	PTGIR	ENSG00000160013	NaN	[NaN]	[157]	1	hSpCas9	negative selection	10388917
46623604	46623627	19	+	28162770	TF1	viability	GGGTGACCGAGCCGTTGCAGAGG	PTGIR	ENSG00000160013	NaN	[NaN]	[22]	1	hSpCas9	negative selection	10388918
46623577	46623600	19	+	28162770	TF1	viability	GCTGGCGGTACATGCGGCAGAGG	PTGIR	ENSG00000160013	NaN	[NaN]	[371]	1	hSpCas9	negative selection	10388919
46623544	46623567	19	+	28162770	TF1	viability	GCCGTGGACCCAGAGAGCCCTGG	PTGIR	ENSG00000160013	NaN	[NaN]	[12]	1	hSpCas9	negative selection	10388920
46623520	46623543	19	-	28162770	TF1	viability	GCGCACCGGAGAGGACGAGGTGG	PTGIR	ENSG00000160013	NaN	[NaN]	[0]	1	hSpCas9	negative selection	10388921
46624190	46624213	19	-	28162770	TF1	viability	GCAGGAACCTCACCTACGTGCGG	PTGIR	ENSG00000160013	NaN	[NaN]	[363]	1	hSpCas9	negative selection	10388922
46623838	46623861	19	+	28162770	SKM1	viability	GCTGCGCGTAGAGGTAGGGGTGG	PTGIR	ENSG00000160013	1.168720488389984	[38]	[154]	9	hSpCas9	negative selection	10558279
46624031	46624054	19	+	28162770	SKM1	viability	GCTGGTGCCCAGCAGGTCGGTGG	PTGIR	ENSG00000160013	0.45598304927775973	[39]	[96]	4	hSpCas9	negative selection	10558280
46623709	46623732	19	+	28162770	SKM1	viability	GGAGGAAGCACCAGCTGCCGGGG	PTGIR	ENSG00000160013	-0.37454272105078423	[32]	[44]	-3	hSpCas9	negative selection	10558281
46624061	46624084	19	+	28162770	SKM1	viability	TCCGGTCACCAGCACCGCGAAGG	PTGIR	ENSG00000160013	1.1966139801453413	[76]	[311]	9	hSpCas9	negative selection	10558282
46623923	46623946	19	+	28162770	SKM1	viability	GAAGGTCATGGCGAAGGCGAAGG	PTGIR	ENSG00000160013	0.8325017359522275	[26]	[84]	7	hSpCas9	negative selection	10558283
46623604	46623627	19	+	28162770	SKM1	viability	GGGTGACCGAGCCGTTGCAGAGG	PTGIR	ENSG00000160013	1.0922684279521107	[12]	[48]	8	hSpCas9	negative selection	10558284
46623577	46623600	19	+	28162770	SKM1	viability	GCTGGCGGTACATGCGGCAGAGG	PTGIR	ENSG00000160013	0.2257514334263625	[103]	[214]	2	hSpCas9	negative selection	10558285
46623544	46623567	19	+	28162770	SKM1	viability	GCCGTGGACCCAGAGAGCCCTGG	PTGIR	ENSG00000160013	-3.034995421356204	[50]	[10]	-9	hSpCas9	negative selection	10558286
46623520	46623543	19	-	28162770	SKM1	viability	GCGCACCGGAGAGGACGAGGTGG	PTGIR	ENSG00000160013	-0.8220016980220057	[2]	[2]	-6	hSpCas9	negative selection	10558287
46624190	46624213	19	-	28162770	SKM1	viability	GCAGGAACCTCACCTACGTGCGG	PTGIR	ENSG00000160013	-0.012332910126154895	[88]	[155]	0	hSpCas9	negative selection	10558288
46623838	46623861	19	+	28162770	SKM1	viability	GCTGCGCGTAGAGGTAGGGGTGG	PTGIR	ENSG00000160013	1.168720488389984	[38]	[154]	9	hSpCas9	negative selection	10727645
46624031	46624054	19	+	28162770	SKM1	viability	GCTGGTGCCCAGCAGGTCGGTGG	PTGIR	ENSG00000160013	0.45598304927775973	[39]	[96]	4	hSpCas9	negative selection	10727646
46623709	46623732	19	+	28162770	SKM1	viability	GGAGGAAGCACCAGCTGCCGGGG	PTGIR	ENSG00000160013	-0.37454272105078423	[32]	[44]	-3	hSpCas9	negative selection	10727647
46624061	46624084	19	+	28162770	SKM1	viability	TCCGGTCACCAGCACCGCGAAGG	PTGIR	ENSG00000160013	1.1966139801453413	[76]	[311]	9	hSpCas9	negative selection	10727648
46623923	46623946	19	+	28162770	SKM1	viability	GAAGGTCATGGCGAAGGCGAAGG	PTGIR	ENSG00000160013	0.8325017359522275	[26]	[84]	7	hSpCas9	negative selection	10727649
46623604	46623627	19	+	28162770	SKM1	viability	GGGTGACCGAGCCGTTGCAGAGG	PTGIR	ENSG00000160013	1.0922684279521107	[12]	[48]	8	hSpCas9	negative selection	10727650
46623577	46623600	19	+	28162770	SKM1	viability	GCTGGCGGTACATGCGGCAGAGG	PTGIR	ENSG00000160013	0.2257514334263625	[103]	[214]	2	hSpCas9	negative selection	10727651
46623544	46623567	19	+	28162770	SKM1	viability	GCCGTGGACCCAGAGAGCCCTGG	PTGIR	ENSG00000160013	-3.034995421356204	[50]	[10]	-9	hSpCas9	negative selection	10727652
46623520	46623543	19	-	28162770	SKM1	viability	GCGCACCGGAGAGGACGAGGTGG	PTGIR	ENSG00000160013	-0.8220016980220057	[2]	[2]	-6	hSpCas9	negative selection	10727653
46624190	46624213	19	-	28162770	SKM1	viability	GCAGGAACCTCACCTACGTGCGG	PTGIR	ENSG00000160013	-0.012332910126154895	[88]	[155]	0	hSpCas9	negative selection	10727654
46623838	46623861	19	+	28162770	PL21	viability	GCTGCGCGTAGAGGTAGGGGTGG	PTGIR	ENSG00000160013	0.1444915849394058	[184]	[88]	1	hSpCas9	negative selection	10897011
46624031	46624054	19	+	28162770	PL21	viability	GCTGGTGCCCAGCAGGTCGGTGG	PTGIR	ENSG00000160013	0.9031578767321887	[85]	[69]	7	hSpCas9	negative selection	10897012
46623709	46623732	19	+	28162770	PL21	viability	GGAGGAAGCACCAGCTGCCGGGG	PTGIR	ENSG00000160013	-0.09531626903685109	[107]	[43]	0	hSpCas9	negative selection	10897013
46624061	46624084	19	+	28162770	PL21	viability	TCCGGTCACCAGCACCGCGAAGG	PTGIR	ENSG00000160013	-0.011836190901789445	[321]	[138]	0	hSpCas9	negative selection	10897014
46623923	46623946	19	+	28162770	PL21	viability	GAAGGTCATGGCGAAGGCGAAGG	PTGIR	ENSG00000160013	-1.1855140780084292	[161]	[30]	-7	hSpCas9	negative selection	10897015
46623604	46623627	19	+	28162770	PL21	viability	GGGTGACCGAGCCGTTGCAGAGG	PTGIR	ENSG00000160013	-4.291713481840355	[44]	[0]	-9	hSpCas9	negative selection	10897016
46623577	46623600	19	+	28162770	PL21	viability	GCTGGCGGTACATGCGGCAGAGG	PTGIR	ENSG00000160013	0.574819376152023	[289]	[187]	5	hSpCas9	negative selection	10897017
46623544	46623567	19	+	28162770	PL21	viability	GCCGTGGACCCAGAGAGCCCTGG	PTGIR	ENSG00000160013	-4.58122009903534	[164]	[2]	-9	hSpCas9	negative selection	10897018
46623520	46623543	19	-	28162770	PL21	viability	GCGCACCGGAGAGGACGAGGTGG	PTGIR	ENSG00000160013	-0.8702497134020781	[20]	[4]	-5	hSpCas9	negative selection	10897019
46624190	46624213	19	-	28162770	PL21	viability	GCAGGAACCTCACCTACGTGCGG	PTGIR	ENSG00000160013	-0.012854108844878254	[305]	[131]	0	hSpCas9	negative selection	10897020
46623838	46623861	19	+	28162770	P31FUJ	viability	GCTGCGCGTAGAGGTAGGGGTGG	PTGIR	ENSG00000160013	-0.10432764646556952	[203]	[222]	-1	hSpCas9	negative selection	11066377
46624031	46624054	19	+	28162770	P31FUJ	viability	GCTGGTGCCCAGCAGGTCGGTGG	PTGIR	ENSG00000160013	0.1140637922228859	[194]	[247]	1	hSpCas9	negative selection	11066378
46623709	46623732	19	+	28162770	P31FUJ	viability	GGAGGAAGCACCAGCTGCCGGGG	PTGIR	ENSG00000160013	-0.5282580879405498	[134]	[109]	-4	hSpCas9	negative selection	11066379
46624061	46624084	19	+	28162770	P31FUJ	viability	TCCGGTCACCAGCACCGCGAAGG	PTGIR	ENSG00000160013	0.5157657012978196	[321]	[540]	6	hSpCas9	negative selection	11066380
46623923	46623946	19	+	28162770	P31FUJ	viability	GAAGGTCATGGCGAAGGCGAAGG	PTGIR	ENSG00000160013	-0.36755161652761614	[156]	[142]	-3	hSpCas9	negative selection	11066381
46623604	46623627	19	+	28162770	P31FUJ	viability	GGGTGACCGAGCCGTTGCAGAGG	PTGIR	ENSG00000160013	0.4958957737682268	[34]	[57]	5	hSpCas9	negative selection	11066382
46623577	46623600	19	+	28162770	P31FUJ	viability	GCTGGCGGTACATGCGGCAGAGG	PTGIR	ENSG00000160013	-0.10419192939854771	[428]	[468]	-1	hSpCas9	negative selection	11066383
46623544	46623567	19	+	28162770	P31FUJ	viability	GCCGTGGACCCAGAGAGCCCTGG	PTGIR	ENSG00000160013	-2.431582068528876	[201]	[43]	-8	hSpCas9	negative selection	11066384
46623520	46623543	19	-	28162770	P31FUJ	viability	GCGCACCGGAGAGGACGAGGTGG	PTGIR	ENSG00000160013	-0.10351918746941191	[31]	[34]	-1	hSpCas9	negative selection	11066385
46624190	46624213	19	-	28162770	P31FUJ	viability	GCAGGAACCTCACCTACGTGCGG	PTGIR	ENSG00000160013	-0.14757890454534883	[492]	[522]	-1	hSpCas9	negative selection	11066386
46623838	46623861	19	+	28162770	OCIAML5	viability	GCTGCGCGTAGAGGTAGGGGTGG	PTGIR	ENSG00000160013	0.2011754504129824	[132]	[275]	1	hSpCas9	negative selection	11235743
46624031	46624054	19	+	28162770	OCIAML5	viability	GCTGGTGCCCAGCAGGTCGGTGG	PTGIR	ENSG00000160013	-0.1457977739207073	[94]	[154]	-1	hSpCas9	negative selection	11235744
46623709	46623732	19	+	28162770	OCIAML5	viability	GGAGGAAGCACCAGCTGCCGGGG	PTGIR	ENSG00000160013	-0.6166885079330685	[78]	[92]	-4	hSpCas9	negative selection	11235745
46624061	46624084	19	+	28162770	OCIAML5	viability	TCCGGTCACCAGCACCGCGAAGG	PTGIR	ENSG00000160013	0.33182603306943503	[216]	[492]	3	hSpCas9	negative selection	11235746
46623923	46623946	19	+	28162770	OCIAML5	viability	GAAGGTCATGGCGAAGGCGAAGG	PTGIR	ENSG00000160013	0.04995826957270552	[98]	[184]	0	hSpCas9	negative selection	11235747
46623604	46623627	19	+	28162770	OCIAML5	viability	GGGTGACCGAGCCGTTGCAGAGG	PTGIR	ENSG00000160013	-1.0155653031468765	[27]	[24]	-6	hSpCas9	negative selection	11235748
46623577	46623600	19	+	28162770	OCIAML5	viability	GCTGGCGGTACATGCGGCAGAGG	PTGIR	ENSG00000160013	0.6802620419491207	[213]	[618]	6	hSpCas9	negative selection	11235749
46623544	46623567	19	+	28162770	OCIAML5	viability	GCCGTGGACCCAGAGAGCCCTGG	PTGIR	ENSG00000160013	-3.095992153750086	[89]	[18]	-9	hSpCas9	negative selection	11235750
46623520	46623543	19	-	28162770	OCIAML5	viability	GCGCACCGGAGAGGACGAGGTGG	PTGIR	ENSG00000160013	-0.5069310848153097	[36]	[46]	-3	hSpCas9	negative selection	11235751
46624190	46624213	19	-	28162770	OCIAML5	viability	GCAGGAACCTCACCTACGTGCGG	PTGIR	ENSG00000160013	-0.018283523528747514	[339]	[605]	0	hSpCas9	negative selection	11235752
46623838	46623861	19	+	28162770	EOL1	viability	GCTGCGCGTAGAGGTAGGGGTGG	PTGIR	ENSG00000160013	0.06997821109209829	[263]	[145]	0	hSpCas9	negative selection	11405109
46624031	46624054	19	+	28162770	EOL1	viability	GCTGGTGCCCAGCAGGTCGGTGG	PTGIR	ENSG00000160013	-0.6243454744431	[157]	[53]	-4	hSpCas9	negative selection	11405110
46623709	46623732	19	+	28162770	EOL1	viability	GGAGGAAGCACCAGCTGCCGGGG	PTGIR	ENSG00000160013	-0.7016373918771346	[212]	[68]	-5	hSpCas9	negative selection	11405111
46624061	46624084	19	+	28162770	EOL1	viability	TCCGGTCACCAGCACCGCGAAGG	PTGIR	ENSG00000160013	0.5534951655745546	[462]	[357]	5	hSpCas9	negative selection	11405112
46623923	46623946	19	+	28162770	EOL1	viability	GAAGGTCATGGCGAAGGCGAAGG	PTGIR	ENSG00000160013	0.789723348016481	[268]	[244]	7	hSpCas9	negative selection	11405113
46623604	46623627	19	+	28162770	EOL1	viability	GGGTGACCGAGCCGTTGCAGAGG	PTGIR	ENSG00000160013	-0.4219026424508969	[88]	[34]	-3	hSpCas9	negative selection	11405114
46623577	46623600	19	+	28162770	EOL1	viability	GCTGGCGGTACATGCGGCAGAGG	PTGIR	ENSG00000160013	0.1343949395878687	[395]	[228]	1	hSpCas9	negative selection	11405115
46623544	46623567	19	+	28162770	EOL1	viability	GCCGTGGACCCAGAGAGCCCTGG	PTGIR	ENSG00000160013	-2.173942091828829	[196]	[22]	-8	hSpCas9	negative selection	11405116
46623520	46623543	19	-	28162770	EOL1	viability	GCGCACCGGAGAGGACGAGGTGG	PTGIR	ENSG00000160013	-3.7193084182041902	[24]	[0]	-9	hSpCas9	negative selection	11405117
46624190	46624213	19	-	28162770	EOL1	viability	GCAGGAACCTCACCTACGTGCGG	PTGIR	ENSG00000160013	0.3760709821995669	[448]	[306]	3	hSpCas9	negative selection	11405118
46623838	46623861	19	+	28162770	MOLM13	viability	GCTGCGCGTAGAGGTAGGGGTGG	PTGIR	ENSG00000160013	0.4457786799388304	[262]	[258]	3	hSpCas9	negative selection	11574475
46624031	46624054	19	+	28162770	MOLM13	viability	GCTGGTGCCCAGCAGGTCGGTGG	PTGIR	ENSG00000160013	0.9207950664138658	[140]	[192]	7	hSpCas9	negative selection	11574476
46623709	46623732	19	+	28162770	MOLM13	viability	GGAGGAAGCACCAGCTGCCGGGG	PTGIR	ENSG00000160013	-1.3520290019769374	[172]	[48]	-6	hSpCas9	negative selection	11574477
46624061	46624084	19	+	28162770	MOLM13	viability	TCCGGTCACCAGCACCGCGAAGG	PTGIR	ENSG00000160013	1.513130970006932	[360]	[744]	9	hSpCas9	negative selection	11574478
46623923	46623946	19	+	28162770	MOLM13	viability	GAAGGTCATGGCGAAGGCGAAGG	PTGIR	ENSG00000160013	0.2061840361833048	[216]	[180]	1	hSpCas9	negative selection	11574479
46623604	46623627	19	+	28162770	MOLM13	viability	GGGTGACCGAGCCGTTGCAGAGG	PTGIR	ENSG00000160013	0.0032211145411347175	[68]	[49]	0	hSpCas9	negative selection	11574480
46623577	46623600	19	+	28162770	MOLM13	viability	GCTGGCGGTACATGCGGCAGAGG	PTGIR	ENSG00000160013	-1.2094940506173222	[418]	[130]	-6	hSpCas9	negative selection	11574481
46623544	46623567	19	+	28162770	MOLM13	viability	GCCGTGGACCCAGAGAGCCCTGG	PTGIR	ENSG00000160013	-4.6195734597057605	[237]	[6]	-9	hSpCas9	negative selection	11574482
46623520	46623543	19	-	28162770	MOLM13	viability	GCGCACCGGAGAGGACGAGGTGG	PTGIR	ENSG00000160013	-1.43900121406394	[14]	[3]	-6	hSpCas9	negative selection	11574483
46624190	46624213	19	-	28162770	MOLM13	viability	GCAGGAACCTCACCTACGTGCGG	PTGIR	ENSG00000160013	-1.0282197283815828	[487]	[172]	-5	hSpCas9	negative selection	11574484
46623838	46623861	19	+	28162770	HEL	viability	GCTGCGCGTAGAGGTAGGGGTGG	PTGIR	ENSG00000160013	0.6505161825920762	[184]	[185]	5	hSpCas9	negative selection	11743841
46624031	46624054	19	+	28162770	HEL	viability	GCTGGTGCCCAGCAGGTCGGTGG	PTGIR	ENSG00000160013	1.2707700546133993	[131]	[203]	9	hSpCas9	negative selection	11743842
46623709	46623732	19	+	28162770	HEL	viability	GGAGGAAGCACCAGCTGCCGGGG	PTGIR	ENSG00000160013	-0.04107705564708464	[150]	[93]	0	hSpCas9	negative selection	11743843
46624061	46624084	19	+	28162770	HEL	viability	TCCGGTCACCAGCACCGCGAAGG	PTGIR	ENSG00000160013	0.3157218604401949	[354]	[282]	2	hSpCas9	negative selection	11743844
46623923	46623946	19	+	28162770	HEL	viability	GAAGGTCATGGCGAAGGCGAAGG	PTGIR	ENSG00000160013	1.1917220356159464	[202]	[296]	9	hSpCas9	negative selection	11743845
46623604	46623627	19	+	28162770	HEL	viability	GGGTGACCGAGCCGTTGCAGAGG	PTGIR	ENSG00000160013	-0.8642211567195264	[53]	[18]	-5	hSpCas9	negative selection	11743846
46623577	46623600	19	+	28162770	HEL	viability	GCTGGCGGTACATGCGGCAGAGG	PTGIR	ENSG00000160013	-0.32483969030726556	[351]	[179]	-2	hSpCas9	negative selection	11743847
46623544	46623567	19	+	28162770	HEL	viability	GCCGTGGACCCAGAGAGCCCTGG	PTGIR	ENSG00000160013	-5.872961006283686	[182]	[1]	-9	hSpCas9	negative selection	11743848
46623520	46623543	19	-	28162770	HEL	viability	GCGCACCGGAGAGGACGAGGTGG	PTGIR	ENSG00000160013	1.642738832000357	[30]	[61]	9	hSpCas9	negative selection	11743849
46624190	46624213	19	-	28162770	HEL	viability	GCAGGAACCTCACCTACGTGCGG	PTGIR	ENSG00000160013	0.03701777111240345	[419]	[275]	0	hSpCas9	negative selection	11743850
46623838	46623861	19	+	28162770	MV411	viability	GCTGCGCGTAGAGGTAGGGGTGG	PTGIR	ENSG00000160013	-0.2495002021411566	[150]	[106]	-2	hSpCas9	negative selection	11913207
46624031	46624054	19	+	28162770	MV411	viability	GCTGGTGCCCAGCAGGTCGGTGG	PTGIR	ENSG00000160013	1.4713013593358915	[139]	[326]	9	hSpCas9	negative selection	11913208
46623709	46623732	19	+	28162770	MV411	viability	GGAGGAAGCACCAGCTGCCGGGG	PTGIR	ENSG00000160013	-0.3881510230083489	[86]	[55]	-3	hSpCas9	negative selection	11913209
46624061	46624084	19	+	28162770	MV411	viability	TCCGGTCACCAGCACCGCGAAGG	PTGIR	ENSG00000160013	-0.8016569987453943	[268]	[129]	-5	hSpCas9	negative selection	11913210
46623923	46623946	19	+	28162770	MV411	viability	GAAGGTCATGGCGAAGGCGAAGG	PTGIR	ENSG00000160013	-0.47555510083082647	[136]	[82]	-4	hSpCas9	negative selection	11913211
46623604	46623627	19	+	28162770	MV411	viability	GGGTGACCGAGCCGTTGCAGAGG	PTGIR	ENSG00000160013	-1.03267036840996	[50]	[20]	-6	hSpCas9	negative selection	11913212
46623577	46623600	19	+	28162770	MV411	viability	GCTGGCGGTACATGCGGCAGAGG	PTGIR	ENSG00000160013	-0.7046279721535228	[295]	[152]	-5	hSpCas9	negative selection	11913213
46623544	46623567	19	+	28162770	MV411	viability	GCCGTGGACCCAGAGAGCCCTGG	PTGIR	ENSG00000160013	-4.296882965441035	[139]	[5]	-9	hSpCas9	negative selection	11913214
46623520	46623543	19	-	28162770	MV411	viability	GCGCACCGGAGAGGACGAGGTGG	PTGIR	ENSG00000160013	-1.1448798719959847	[20]	[7]	-6	hSpCas9	negative selection	11913215
46624190	46624213	19	-	28162770	MV411	viability	GCAGGAACCTCACCTACGTGCGG	PTGIR	ENSG00000160013	-0.7315621506046723	[340]	[172]	-5	hSpCas9	negative selection	11913216
46623838	46623861	19	+	28162770	MONOMAC1	viability	GCTGCGCGTAGAGGTAGGGGTGG	PTGIR	ENSG00000160013	-0.06813911387729607	[106]	[116]	0	hSpCas9	negative selection	12082573
46624031	46624054	19	+	28162770	MONOMAC1	viability	GCTGGTGCCCAGCAGGTCGGTGG	PTGIR	ENSG00000160013	0.04738188060689319	[64]	[76]	0	hSpCas9	negative selection	12082574
46623709	46623732	19	+	28162770	MONOMAC1	viability	GGAGGAAGCACCAGCTGCCGGGG	PTGIR	ENSG00000160013	-1.272324974363791	[58]	[27]	-7	hSpCas9	negative selection	12082575
46624061	46624084	19	+	28162770	MONOMAC1	viability	TCCGGTCACCAGCACCGCGAAGG	PTGIR	ENSG00000160013	-0.11214794947304085	[197]	[209]	-1	hSpCas9	negative selection	12082576
46623923	46623946	19	+	28162770	MONOMAC1	viability	GAAGGTCATGGCGAAGGCGAAGG	PTGIR	ENSG00000160013	-0.1970368470595537	[104]	[104]	-2	hSpCas9	negative selection	12082577
46623604	46623627	19	+	28162770	MONOMAC1	viability	GGGTGACCGAGCCGTTGCAGAGG	PTGIR	ENSG00000160013	-1.2514846310819303	[26]	[12]	-7	hSpCas9	negative selection	12082578
46623577	46623600	19	+	28162770	MONOMAC1	viability	GCTGGCGGTACATGCGGCAGAGG	PTGIR	ENSG00000160013	-0.21206505629188532	[192]	[190]	-2	hSpCas9	negative selection	12082579
46623544	46623567	19	+	28162770	MONOMAC1	viability	GCCGTGGACCCAGAGAGCCCTGG	PTGIR	ENSG00000160013	-1.2824283382901982	[86]	[40]	-7	hSpCas9	negative selection	12082580
46623520	46623543	19	-	28162770	MONOMAC1	viability	GCGCACCGGAGAGGACGAGGTGG	PTGIR	ENSG00000160013	0.8029631529404462	[5]	[11]	7	hSpCas9	negative selection	12082581
46624190	46624213	19	-	28162770	MONOMAC1	viability	GCAGGAACCTCACCTACGTGCGG	PTGIR	ENSG00000160013	0.48510472236213076	[176]	[283]	5	hSpCas9	negative selection	12082582
46623838	46623861	19	+	28162770	OCIAML2	viability	GCTGCGCGTAGAGGTAGGGGTGG	PTGIR	ENSG00000160013	0.28069106190111515	[29]	[201]	2	hSpCas9	negative selection	12251939
46624031	46624054	19	+	28162770	OCIAML2	viability	GCTGGTGCCCAGCAGGTCGGTGG	PTGIR	ENSG00000160013	0.41201322411968	[23]	[176]	4	hSpCas9	negative selection	12251940
46623709	46623732	19	+	28162770	OCIAML2	viability	GGAGGAAGCACCAGCTGCCGGGG	PTGIR	ENSG00000160013	0.3706724287387805	[23]	[171]	3	hSpCas9	negative selection	12251941
46624061	46624084	19	+	28162770	OCIAML2	viability	TCCGGTCACCAGCACCGCGAAGG	PTGIR	ENSG00000160013	0.37006228068955527	[54]	[393]	3	hSpCas9	negative selection	12251942
46623923	46623946	19	+	28162770	OCIAML2	viability	GAAGGTCATGGCGAAGGCGAAGG	PTGIR	ENSG00000160013	0.6026191567884774	[23]	[201]	6	hSpCas9	negative selection	12251943
46623604	46623627	19	+	28162770	OCIAML2	viability	GGGTGACCGAGCCGTTGCAGAGG	PTGIR	ENSG00000160013	0.3178660695641271	[10]	[75]	3	hSpCas9	negative selection	12251944
46623577	46623600	19	+	28162770	OCIAML2	viability	GCTGGCGGTACATGCGGCAGAGG	PTGIR	ENSG00000160013	-0.2398496184129941	[48]	[229]	-2	hSpCas9	negative selection	12251945
46623544	46623567	19	+	28162770	OCIAML2	viability	GCCGTGGACCCAGAGAGCCCTGG	PTGIR	ENSG00000160013	-3.0362270010963863	[36]	[24]	-9	hSpCas9	negative selection	12251946
46623520	46623543	19	-	28162770	OCIAML2	viability	GCGCACCGGAGAGGACGAGGTGG	PTGIR	ENSG00000160013	1.658653191702805	[1]	[34]	9	hSpCas9	negative selection	12251947
46624190	46624213	19	-	28162770	OCIAML2	viability	GCAGGAACCTCACCTACGTGCGG	PTGIR	ENSG00000160013	-0.20116915024893456	[55]	[269]	-2	hSpCas9	negative selection	12251948
46623838	46623861	19	+	28162770	OCIAML3	viability	GCTGCGCGTAGAGGTAGGGGTGG	PTGIR	ENSG00000160013	1.2184905850094006	[39]	[280]	8	hSpCas9	negative selection	12421305
46624031	46624054	19	+	28162770	OCIAML3	viability	GCTGGTGCCCAGCAGGTCGGTGG	PTGIR	ENSG00000160013	-0.05967121267297493	[28]	[83]	0	hSpCas9	negative selection	12421306
46623709	46623732	19	+	28162770	OCIAML3	viability	GGAGGAAGCACCAGCTGCCGGGG	PTGIR	ENSG00000160013	0.6744811956017387	[21]	[105]	6	hSpCas9	negative selection	12421307
46624061	46624084	19	+	28162770	OCIAML3	viability	TCCGGTCACCAGCACCGCGAAGG	PTGIR	ENSG00000160013	0.5676733670232408	[77]	[348]	5	hSpCas9	negative selection	12421308
46623923	46623946	19	+	28162770	OCIAML3	viability	GAAGGTCATGGCGAAGGCGAAGG	PTGIR	ENSG00000160013	-0.386682667076657	[54]	[126]	-3	hSpCas9	negative selection	12421309
46623604	46623627	19	+	28162770	OCIAML3	viability	GGGTGACCGAGCCGTTGCAGAGG	PTGIR	ENSG00000160013	0.790656209911162	[8]	[46]	7	hSpCas9	negative selection	12421310
46623577	46623600	19	+	28162770	OCIAML3	viability	GCTGGCGGTACATGCGGCAGAGG	PTGIR	ENSG00000160013	-0.22291348863291632	[74]	[193]	-2	hSpCas9	negative selection	12421311
46623544	46623567	19	+	28162770	OCIAML3	viability	GCCGTGGACCCAGAGAGCCCTGG	PTGIR	ENSG00000160013	-0.9104813051194174	[65]	[105]	-6	hSpCas9	negative selection	12421312
46623520	46623543	19	-	28162770	OCIAML3	viability	GCGCACCGGAGAGGACGAGGTGG	PTGIR	ENSG00000160013	-2.7639326417664756	[8]	[3]	-9	hSpCas9	negative selection	12421313
46624190	46624213	19	-	28162770	OCIAML3	viability	GCAGGAACCTCACCTACGTGCGG	PTGIR	ENSG00000160013	0.7314782739763882	[80]	[405]	6	hSpCas9	negative selection	12421314