Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:11099
• Symbol:PTPN21
• Description:protein tyrosine phosphatase non-receptor type 21

DataSource: http://genomecrispr.dkfz.de/#!/results/PTPN21

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
88517214	88517237	14	-	26472758	Jiyoye	viability	ACAACAAGCAAAATCAGCGCCGG	PTPN21	ENSG00000070778	1.1758498353994176	[26]	[45]	7	hSpCas9	negative selection	131019
88479848	88479871	14	+	26472758	Jiyoye	viability	GCAGGGTAGGGGTAGGGAGACGG	PTPN21	ENSG00000070778	-6.887445367385753	[156]	[0]	-9	hSpCas9	negative selection	131020
88480049	88480072	14	-	26472758	Jiyoye	viability	GTGATGAAGCAGCTCAACAGGGG	PTPN21	ENSG00000070778	-0.04700051167992872	[136]	[99]	0	hSpCas9	negative selection	131021
88479366	88479389	14	-	26472758	Jiyoye	viability	GACACAGCGAGAAGGGCCGGAGG	PTPN21	ENSG00000070778	5.314065977114391	[0]	[29]	9	hSpCas9	negative selection	131022
88479267	88479290	14	-	26472758	Jiyoye	viability	GGAGGACGAGGACTTCGAGGAGG	PTPN21	ENSG00000070778	-0.42932588621124723	[74]	[41]	-3	hSpCas9	negative selection	131023
88550237	88550260	14	-	26472758	Jiyoye	viability	CCAGAGGCTGGAGCTGCGGGAGG	PTPN21	ENSG00000070778	-0.4841183590516267	[114]	[61]	-3	hSpCas9	negative selection	131024
88517162	88517185	14	-	26472758	Jiyoye	viability	GCAGCTGGATAAATATGCATTGG	PTPN21	ENSG00000070778	1.7567598192961011	[30]	[78]	8	hSpCas9	negative selection	131025
88485803	88485826	14	-	26472758	Jiyoye	viability	CAGTGAACCCAATCAGGAGGAGG	PTPN21	ENSG00000070778	1.9503177065324027	[34]	[101]	8	hSpCas9	negative selection	131026
88480175	88480198	14	+	26472758	Jiyoye	viability	GGGTTGGACGACATCGGCGAGGG	PTPN21	ENSG00000070778	-0.41552008668621687	[259]	[146]	-3	hSpCas9	negative selection	131027
88517214	88517237	14	-	26472758	KBM7	viability	ACAACAAGCAAAATCAGCGCCGG	PTPN21	ENSG00000070778	-0.23244229150437434	[296,355]	[169,98]	-2	hSpCas9	negative selection	322137
88479848	88479871	14	+	26472758	KBM7	viability	GCAGGGTAGGGGTAGGGAGACGG	PTPN21	ENSG00000070778	-3.246792792552319	[288,503]	[14,24]	-9	hSpCas9	negative selection	322138
88480049	88480072	14	-	26472758	KBM7	viability	GTGATGAAGCAGCTCAACAGGGG	PTPN21	ENSG00000070778	0.6366679187472087	[487,514]	[427,316]	7	hSpCas9	negative selection	322139
88479366	88479389	14	-	26472758	KBM7	viability	GACACAGCGAGAAGGGCCGGAGG	PTPN21	ENSG00000070778	1.014620483860367	[136,56]	[131,49]	9	hSpCas9	negative selection	322140
88479267	88479290	14	-	26472758	KBM7	viability	GGAGGACGAGGACTTCGAGGAGG	PTPN21	ENSG00000070778	-0.8252465785326402	[419,357]	[104,100]	-6	hSpCas9	negative selection	322141
88550237	88550260	14	-	26472758	KBM7	viability	CCAGAGGCTGGAGCTGCGGGAGG	PTPN21	ENSG00000070778	0.8421054693034378	[371,109]	[280,113]	8	hSpCas9	negative selection	322142
88517162	88517185	14	-	26472758	KBM7	viability	GCAGCTGGATAAATATGCATTGG	PTPN21	ENSG00000070778	-0.17322317642407187	[436,533]	[280,137]	-2	hSpCas9	negative selection	322143
88485803	88485826	14	-	26472758	KBM7	viability	CAGTGAACCCAATCAGGAGGAGG	PTPN21	ENSG00000070778	-0.08213730543087194	[322,320]	[130,154]	-1	hSpCas9	negative selection	322144
88480175	88480198	14	+	26472758	KBM7	viability	GGGTTGGACGACATCGGCGAGGG	PTPN21	ENSG00000070778	0.5739924398740694	[903,875]	[549,691]	6	hSpCas9	negative selection	322145
88517214	88517237	14	-	26472758	Raji	viability	ACAACAAGCAAAATCAGCGCCGG	PTPN21	ENSG00000070778	-1.5819156251622923	[128]	[9]	-8	hSpCas9	negative selection	513255
88479848	88479871	14	+	26472758	Raji	viability	GCAGGGTAGGGGTAGGGAGACGG	PTPN21	ENSG00000070778	-3.12965566192725	[263]	[6]	-9	hSpCas9	negative selection	513256
88480049	88480072	14	-	26472758	Raji	viability	GTGATGAAGCAGCTCAACAGGGG	PTPN21	ENSG00000070778	0.2581149715826011	[226]	[62]	2	hSpCas9	negative selection	513257
88479366	88479389	14	-	26472758	Raji	viability	GACACAGCGAGAAGGGCCGGAGG	PTPN21	ENSG00000070778	-0.36392218355198946	[60]	[10]	-3	hSpCas9	negative selection	513258
88479267	88479290	14	-	26472758	Raji	viability	GGAGGACGAGGACTTCGAGGAGG	PTPN21	ENSG00000070778	-1.1020698302553504	[147]	[15]	-7	hSpCas9	negative selection	513259
88550237	88550260	14	-	26472758	Raji	viability	CCAGAGGCTGGAGCTGCGGGAGG	PTPN21	ENSG00000070778	-0.6031098474314156	[215]	[32]	-5	hSpCas9	negative selection	513260
88517162	88517185	14	-	26472758	Raji	viability	GCAGCTGGATAAATATGCATTGG	PTPN21	ENSG00000070778	0.6219567082033579	[181]	[64]	6	hSpCas9	negative selection	513261
88485803	88485826	14	-	26472758	Raji	viability	CAGTGAACCCAATCAGGAGGAGG	PTPN21	ENSG00000070778	0.325664540302845	[250]	[72]	3	hSpCas9	negative selection	513262
88480175	88480198	14	+	26472758	Raji	viability	GGGTTGGACGACATCGGCGAGGG	PTPN21	ENSG00000070778	0.6282156986750401	[275]	[98]	6	hSpCas9	negative selection	513263
88517214	88517237	14	-	26472758	K562	viability	ACAACAAGCAAAATCAGCGCCGG	PTPN21	ENSG00000070778	-0.21014713579903432	[184]	[134]	-1	hSpCas9	negative selection	704373
88479848	88479871	14	+	26472758	K562	viability	GCAGGGTAGGGGTAGGGAGACGG	PTPN21	ENSG00000070778	-8.317823696554624	[377]	[0]	-9	hSpCas9	negative selection	704374
88480049	88480072	14	-	26472758	K562	viability	GTGATGAAGCAGCTCAACAGGGG	PTPN21	ENSG00000070778	-0.2179244863907535	[371]	[269]	-1	hSpCas9	negative selection	704375
88479366	88479389	14	-	26472758	K562	viability	GACACAGCGAGAAGGGCCGGAGG	PTPN21	ENSG00000070778	1.0233918483542284	[87]	[150]	8	hSpCas9	negative selection	704376
88479267	88479290	14	-	26472758	K562	viability	GGAGGACGAGGACTTCGAGGAGG	PTPN21	ENSG00000070778	-0.19871107864174986	[241]	[177]	-1	hSpCas9	negative selection	704377
88550237	88550260	14	-	26472758	K562	viability	CCAGAGGCTGGAGCTGCGGGAGG	PTPN21	ENSG00000070778	1.3288109149568192	[248]	[527]	9	hSpCas9	negative selection	704378
88517162	88517185	14	-	26472758	K562	viability	GCAGCTGGATAAATATGCATTGG	PTPN21	ENSG00000070778	0.7536386660019984	[377]	[537]	6	hSpCas9	negative selection	704379
88485803	88485826	14	-	26472758	K562	viability	CAGTGAACCCAATCAGGAGGAGG	PTPN21	ENSG00000070778	1.6479713544481904	[267]	[708]	9	hSpCas9	negative selection	704380
88480175	88480198	14	+	26472758	K562	viability	GGGTTGGACGACATCGGCGAGGG	PTPN21	ENSG00000070778	0.2757450618603523	[819]	[837]	2	hSpCas9	negative selection	704381
88485075	88485098	14	-	26627737	DLD1	viability	GAACCATATGCTTCTTCCCAAGG	PTPN21	ENSG00000070778	-0.14733126601258562	[278]	[85,94,58]	-1	hSpCas9	negative selection	789648
88485806	88485829	14	-	26627737	DLD1	viability	TCACAGTGAACCCAATCAGGAGG	PTPN21	ENSG00000070778	-0.7303350486981361	[633]	[137,131,92]	-6	hSpCas9	negative selection	789649
88517073	88517096	14	+	26627737	DLD1	viability	ACGGCATGTAATTTCTCACCTGG	PTPN21	ENSG00000070778	0.3812610965762666	[314]	[121,151,113]	4	hSpCas9	negative selection	789650
88550360	88550383	14	+	26627737	DLD1	viability	TGCTGGACACCGTGTAGCGCCGG	PTPN21	ENSG00000070778	-0.3570096644770169	[1262]	[277,367,284]	-4	hSpCas9	negative selection	789651
88485075	88485098	14	-	26627737	GBM cells	viability after 5 days	GAACCATATGCTTCTTCCCAAGG	PTPN21	ENSG00000070778	-0.33374688190458957	[140]	[71,47]	-5	hSpCas9	negative selection	871963
88485806	88485829	14	-	26627737	GBM cells	viability after 5 days	TCACAGTGAACCCAATCAGGAGG	PTPN21	ENSG00000070778	-0.36945397525114876	[270]	[141,82]	-5	hSpCas9	negative selection	871964
88517073	88517096	14	+	26627737	GBM cells	viability after 5 days	ACGGCATGTAATTTCTCACCTGG	PTPN21	ENSG00000070778	-0.2611633406002797	[218]	[85,109]	-4	hSpCas9	negative selection	871965
88550360	88550383	14	+	26627737	GBM cells	viability after 5 days	TGCTGGACACCGTGTAGCGCCGG	PTPN21	ENSG00000070778	-0.8195722986728602	[361]	[89,129]	-8	hSpCas9	negative selection	871966
88485075	88485098	14	-	26627737	GBM cells	viability after 13 days	GAACCATATGCTTCTTCCCAAGG	PTPN21	ENSG00000070778	0.5716215553421933	[140]	[132,97]	7	hSpCas9	negative selection	954278
88485806	88485829	14	-	26627737	GBM cells	viability after 13 days	TCACAGTGAACCCAATCAGGAGG	PTPN21	ENSG00000070778	-0.41051227280506436	[270]	[194,41]	-5	hSpCas9	negative selection	954279
88517073	88517096	14	+	26627737	GBM cells	viability after 13 days	ACGGCATGTAATTTCTCACCTGG	PTPN21	ENSG00000070778	0.11343584575484311	[218]	[111,141]	1	hSpCas9	negative selection	954280
88550360	88550383	14	+	26627737	GBM cells	viability after 13 days	TGCTGGACACCGTGTAGCGCCGG	PTPN21	ENSG00000070778	-0.9724022103616037	[361]	[98,100]	-8	hSpCas9	negative selection	954281
88485075	88485098	14	-	26627737	GBM cells	viability after 21 days	GAACCATATGCTTCTTCCCAAGG	PTPN21	ENSG00000070778	0.10758695082261094	[140]	[69,93]	1	hSpCas9	negative selection	1036593
88485806	88485829	14	-	26627737	GBM cells	viability after 21 days	TCACAGTGAACCCAATCAGGAGG	PTPN21	ENSG00000070778	-0.39972252479638803	[270]	[120,102]	-4	hSpCas9	negative selection	1036594
88517073	88517096	14	+	26627737	GBM cells	viability after 21 days	ACGGCATGTAATTTCTCACCTGG	PTPN21	ENSG00000070778	0.3850826131854086	[218]	[169,141]	4	hSpCas9	negative selection	1036595
88550360	88550383	14	+	26627737	GBM cells	viability after 21 days	TGCTGGACACCGTGTAGCGCCGG	PTPN21	ENSG00000070778	-0.25659730053698543	[361]	[149,177]	-2	hSpCas9	negative selection	1036596
88485075	88485098	14	-	26627737	RPE1	viability after 9 days	GAACCATATGCTTCTTCCCAAGG	PTPN21	ENSG00000070778	1.6089127790591191	[129]	[38,233]	8	hSpCas9	negative selection	1118908
88485806	88485829	14	-	26627737	RPE1	viability after 9 days	TCACAGTGAACCCAATCAGGAGG	PTPN21	ENSG00000070778	-1.6194459812916366	[1130]	[140,81]	-8	hSpCas9	negative selection	1118909
88517073	88517096	14	+	26627737	RPE1	viability after 9 days	ACGGCATGTAATTTCTCACCTGG	PTPN21	ENSG00000070778	-1.668222388490703	[645]	[36,97]	-8	hSpCas9	negative selection	1118910
88550360	88550383	14	+	26627737	RPE1	viability after 9 days	TGCTGGACACCGTGTAGCGCCGG	PTPN21	ENSG00000070778	-0.5335366188382495	[1360]	[320,259]	-4	hSpCas9	negative selection	1118911
88485075	88485098	14	-	26627737	RPE1	viability after 12 days	GAACCATATGCTTCTTCCCAAGG	PTPN21	ENSG00000070778	1.1319394475420959	[129]	[43,110]	6	hSpCas9	negative selection	1201223
88485806	88485829	14	-	26627737	RPE1	viability after 12 days	TCACAGTGAACCCAATCAGGAGG	PTPN21	ENSG00000070778	-0.9666335780119706	[1130]	[222,83]	-6	hSpCas9	negative selection	1201224
88517073	88517096	14	+	26627737	RPE1	viability after 12 days	ACGGCATGTAATTTCTCACCTGG	PTPN21	ENSG00000070778	-1.3439572784272547	[645]	[29,108]	-7	hSpCas9	negative selection	1201225
88550360	88550383	14	+	26627737	RPE1	viability after 12 days	TGCTGGACACCGTGTAGCGCCGG	PTPN21	ENSG00000070778	-1.0993829503341646	[1360]	[209,128]	-6	hSpCas9	negative selection	1201226
88485075	88485098	14	-	26627737	RPE1	viability after 15 days	GAACCATATGCTTCTTCCCAAGG	PTPN21	ENSG00000070778	1.5498796502694268	[129]	[97,116]	8	hSpCas9	negative selection	1283538
88485806	88485829	14	-	26627737	RPE1	viability after 15 days	TCACAGTGAACCCAATCAGGAGG	PTPN21	ENSG00000070778	-0.6266816854644128	[1130]	[335,82]	-4	hSpCas9	negative selection	1283539
88517073	88517096	14	+	26627737	RPE1	viability after 15 days	ACGGCATGTAATTTCTCACCTGG	PTPN21	ENSG00000070778	-1.2158641213978088	[645]	[68,87]	-6	hSpCas9	negative selection	1283540
88550360	88550383	14	+	26627737	RPE1	viability after 15 days	TGCTGGACACCGTGTAGCGCCGG	PTPN21	ENSG00000070778	-1.0667024178400164	[1360]	[194,172]	-6	hSpCas9	negative selection	1283541
88485075	88485098	14	-	26627737	RPE1	viability after 18 days	GAACCATATGCTTCTTCCCAAGG	PTPN21	ENSG00000070778	0.9371605920639261	[129]	[13,123]	5	hSpCas9	negative selection	1365853
88485806	88485829	14	-	26627737	RPE1	viability after 18 days	TCACAGTGAACCCAATCAGGAGG	PTPN21	ENSG00000070778	-0.5133027210402974	[1130]	[252,171]	-3	hSpCas9	negative selection	1365854
88517073	88517096	14	+	26627737	RPE1	viability after 18 days	ACGGCATGTAATTTCTCACCTGG	PTPN21	ENSG00000070778	-1.5167792935793494	[645]	[14,109]	-7	hSpCas9	negative selection	1365855
88550360	88550383	14	+	26627737	RPE1	viability after 18 days	TGCTGGACACCGTGTAGCGCCGG	PTPN21	ENSG00000070778	-1.2908708287186528	[1360]	[269,21]	-7	hSpCas9	negative selection	1365856
88485075	88485098	14	-	26627737	HeLa	viability after 8 days	GAACCATATGCTTCTTCCCAAGG	PTPN21	ENSG00000070778	-1.667889846858628	[169]	[32,15,22]	-9	hSpCas9	negative selection	1448168
88485806	88485829	14	-	26627737	HeLa	viability after 8 days	TCACAGTGAACCCAATCAGGAGG	PTPN21	ENSG00000070778	0.3539917544248248	[239]	[248,15,158]	3	hSpCas9	negative selection	1448169
88517073	88517096	14	+	26627737	HeLa	viability after 8 days	ACGGCATGTAATTTCTCACCTGG	PTPN21	ENSG00000070778	-0.15363282576065168	[438]	[249,74,204]	-1	hSpCas9	negative selection	1448170
88550360	88550383	14	+	26627737	HeLa	viability after 8 days	TGCTGGACACCGTGTAGCGCCGG	PTPN21	ENSG00000070778	-0.5207672319755401	[1089]	[441,209,361]	-5	hSpCas9	negative selection	1448171
88485075	88485098	14	-	26627737	HeLa	viability after 12 days	GAACCATATGCTTCTTCCCAAGG	PTPN21	ENSG00000070778	0.5527047364440077	[169]	[88,128,87]	4	hSpCas9	negative selection	1530483
88485806	88485829	14	-	26627737	HeLa	viability after 12 days	TCACAGTGAACCCAATCAGGAGG	PTPN21	ENSG00000070778	0.10195577098637643	[239]	[83,27,214]	0	hSpCas9	negative selection	1530484
88517073	88517096	14	+	26627737	HeLa	viability after 12 days	ACGGCATGTAATTTCTCACCTGG	PTPN21	ENSG00000070778	0.8101509130248183	[438]	[592,103,287]	6	hSpCas9	negative selection	1530485
88550360	88550383	14	+	26627737	HeLa	viability after 12 days	TGCTGGACACCGTGTAGCGCCGG	PTPN21	ENSG00000070778	-0.7826940428083519	[1089]	[168,297,311]	-6	hSpCas9	negative selection	1530486
88485075	88485098	14	-	26627737	HeLa	viability after 15 days	GAACCATATGCTTCTTCCCAAGG	PTPN21	ENSG00000070778	0.6327053505073725	[169]	[33,203,82]	5	hSpCas9	negative selection	1612798
88485806	88485829	14	-	26627737	HeLa	viability after 15 days	TCACAGTGAACCCAATCAGGAGG	PTPN21	ENSG00000070778	0.28947721228014306	[239]	[97,86,177]	2	hSpCas9	negative selection	1612799
88517073	88517096	14	+	26627737	HeLa	viability after 15 days	ACGGCATGTAATTTCTCACCTGG	PTPN21	ENSG00000070778	0.40181544161794996	[438]	[217,176,319]	3	hSpCas9	negative selection	1612800
88550360	88550383	14	+	26627737	HeLa	viability after 15 days	TGCTGGACACCGTGTAGCGCCGG	PTPN21	ENSG00000070778	-0.2421609433377121	[1089]	[566,108,452]	-2	hSpCas9	negative selection	1612801
88485075	88485098	14	-	26627737	HeLa	viability after 18 days	GAACCATATGCTTCTTCCCAAGG	PTPN21	ENSG00000070778	0.6846584790369044	[169]	[27,171,82]	5	hSpCas9	negative selection	1695113
88485806	88485829	14	-	26627737	HeLa	viability after 18 days	TCACAGTGAACCCAATCAGGAGG	PTPN21	ENSG00000070778	0.26577221977823695	[239]	[61,71,177]	2	hSpCas9	negative selection	1695114
88517073	88517096	14	+	26627737	HeLa	viability after 18 days	ACGGCATGTAATTTCTCACCTGG	PTPN21	ENSG00000070778	0.3600050537019141	[438]	[135,142,319]	3	hSpCas9	negative selection	1695115
88550360	88550383	14	+	26627737	HeLa	viability after 18 days	TGCTGGACACCGTGTAGCGCCGG	PTPN21	ENSG00000070778	-0.2661665873126031	[1089]	[362,96,452]	-2	hSpCas9	negative selection	1695116
88485075	88485098	14	-	26627737	HCT116	viability after 6 days	GAACCATATGCTTCTTCCCAAGG	PTPN21	ENSG00000070778	1.1118654303571722	[183]	[164,5]	6	hSpCas9	negative selection	1777428
88485806	88485829	14	-	26627737	HCT116	viability after 6 days	TCACAGTGAACCCAATCAGGAGG	PTPN21	ENSG00000070778	-0.1533649871395888	[509]	[64,75]	-1	hSpCas9	negative selection	1777429
88517073	88517096	14	+	26627737	HCT116	viability after 6 days	ACGGCATGTAATTTCTCACCTGG	PTPN21	ENSG00000070778	0.5352232301498965	[328]	[92,64]	3	hSpCas9	negative selection	1777430
88550360	88550383	14	+	26627737	HCT116	viability after 6 days	TGCTGGACACCGTGTAGCGCCGG	PTPN21	ENSG00000070778	-0.8957684328270956	[1708]	[291,62]	-5	hSpCas9	negative selection	1777431
88485075	88485098	14	-	26627737	HCT116	viability after 8 days	GAACCATATGCTTCTTCCCAAGG	PTPN21	ENSG00000070778	1.6972582060662975	[26]	[48,67,27]	9	hSpCas9	negative selection	1859743
88485806	88485829	14	-	26627737	HCT116	viability after 8 days	TCACAGTGAACCCAATCAGGAGG	PTPN21	ENSG00000070778	-0.49824410292749305	[253]	[62,165,67]	-5	hSpCas9	negative selection	1859744
88517073	88517096	14	+	26627737	HCT116	viability after 8 days	ACGGCATGTAATTTCTCACCTGG	PTPN21	ENSG00000070778	0.14372984931182844	[280]	[223,108,180]	1	hSpCas9	negative selection	1859745
88550360	88550383	14	+	26627737	HCT116	viability after 8 days	TGCTGGACACCGTGTAGCGCCGG	PTPN21	ENSG00000070778	0.07908443891277606	[557]	[261,363,346]	0	hSpCas9	negative selection	1859746
88485075	88485098	14	-	26627737	HCT116	viability after 9 days	GAACCATATGCTTCTTCCCAAGG	PTPN21	ENSG00000070778	0.889650912733902	[183]	[85,94]	6	hSpCas9	negative selection	1942058
88485806	88485829	14	-	26627737	HCT116	viability after 9 days	TCACAGTGAACCCAATCAGGAGG	PTPN21	ENSG00000070778	-0.7258010419100631	[509]	[59,99]	-5	hSpCas9	negative selection	1942059
88517073	88517096	14	+	26627737	HCT116	viability after 9 days	ACGGCATGTAATTTCTCACCTGG	PTPN21	ENSG00000070778	0.3140893081727367	[328]	[68,140]	2	hSpCas9	negative selection	1942060
88550360	88550383	14	+	26627737	HCT116	viability after 9 days	TGCTGGACACCGTGTAGCGCCGG	PTPN21	ENSG00000070778	0.293966142939581	[1708]	[368,709]	2	hSpCas9	negative selection	1942061
88485075	88485098	14	-	26627737	HCT116	viability after 12 days	GAACCATATGCTTCTTCCCAAGG	PTPN21	ENSG00000070778	2.2364980985987652	[26]	[33,87,81]	9	hSpCas9	negative selection	2024373
88485806	88485829	14	-	26627737	HCT116	viability after 12 days	TCACAGTGAACCCAATCAGGAGG	PTPN21	ENSG00000070778	-0.2081007737199797	[253]	[61,182,107]	-2	hSpCas9	negative selection	2024374
88517073	88517096	14	+	26627737	HCT116	viability after 12 days	ACGGCATGTAATTTCTCACCTGG	PTPN21	ENSG00000070778	0.4425292994974177	[280]	[218,140,238]	4	hSpCas9	negative selection	2024375
88550360	88550383	14	+	26627737	HCT116	viability after 12 days	TGCTGGACACCGTGTAGCGCCGG	PTPN21	ENSG00000070778	0.2565862554258268	[557]	[224,309,525]	2	hSpCas9	negative selection	2024376
88485075	88485098	14	-	26627737	HCT116	viability after 15 days	GAACCATATGCTTCTTCCCAAGG	PTPN21	ENSG00000070778	1.981187652644134	[26]	[23,82,71]	9	hSpCas9	negative selection	2106688
88485806	88485829	14	-	26627737	HCT116	viability after 15 days	TCACAGTGAACCCAATCAGGAGG	PTPN21	ENSG00000070778	-0.22057682529961625	[253]	[74,130,162]	-2	hSpCas9	negative selection	2106689
88517073	88517096	14	+	26627737	HCT116	viability after 15 days	ACGGCATGTAATTTCTCACCTGG	PTPN21	ENSG00000070778	0.2713703067982788	[280]	[171,168,239]	2	hSpCas9	negative selection	2106690
88550360	88550383	14	+	26627737	HCT116	viability after 15 days	TGCTGGACACCGTGTAGCGCCGG	PTPN21	ENSG00000070778	-0.1671556867566394	[557]	[294,329,232]	-2	hSpCas9	negative selection	2106691
88485075	88485098	14	-	26627737	HCT116	viability after 18 days	GAACCATATGCTTCTTCCCAAGG	PTPN21	ENSG00000070778	1.9146842485544813	[26]	[57,33,56]	9	hSpCas9	negative selection	2189003
88485806	88485829	14	-	26627737	HCT116	viability after 18 days	TCACAGTGAACCCAATCAGGAGG	PTPN21	ENSG00000070778	0.1362422542888692	[253]	[48,211,138]	1	hSpCas9	negative selection	2189004
88517073	88517096	14	+	26627737	HCT116	viability after 18 days	ACGGCATGTAATTTCTCACCTGG	PTPN21	ENSG00000070778	0.343837146579821	[280]	[293,55,174]	3	hSpCas9	negative selection	2189005
88550360	88550383	14	+	26627737	HCT116	viability after 18 days	TGCTGGACACCGTGTAGCGCCGG	PTPN21	ENSG00000070778	0.5864801524526696	[557]	[360,544,294]	5	hSpCas9	negative selection	2189006
88474985	88475008	14	+	25494202	A375	resistance to PLX-4720 (puromycin)	GGGAGGCTGAGGCAGGAGAAAGG	PTPN21	ENSG00000070778	-0.8896445471743792	[26,0]	[0,0]	-5	dCas9-VP64	positive selection	2422251
88474985	88475008	14	+	25494202	A375	resistance to PLX-4720 (zeocin)	GGGAGGCTGAGGCAGGAGAAAGG	PTPN21	ENSG00000070778	0.4958448470370793	[21,20]	[10,7]	4	dCas9-VP64	positive selection	2517506
88479953	88479976	14	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CTGGCTGTAGACCAGCGCCGCGG	PTPN21	ENSG00000070778	0.04015489714765495	[3,2]	[3,2]	0	hSpCas9	positive selection	3014710
88480176	88480199	14	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GGGTTGGACGACATCGGCGAGGG	PTPN21	ENSG00000070778	-0.4311505800767695	[4,4]	[4,1]	-6	hSpCas9	positive selection	3014711
88479969	88479992	14	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GTACGCCTACAGCAGGCCCGCGG	PTPN21	ENSG00000070778	-0.7335868401414458	[2,2]	[1,0]	-8	hSpCas9	positive selection	3014712
88479953	88479976	14	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CTGGCTGTAGACCAGCGCCGCGG	PTPN21	ENSG00000070778	-0.1749908184831192	[3,3]	[2,0]	-3	hSpCas9	positive selection	3082568
88480176	88480199	14	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GGGTTGGACGACATCGGCGAGGG	PTPN21	ENSG00000070778	-0.2679371275871679	[4,4]	[3,1]	-4	hSpCas9	positive selection	3082569
88479969	88479992	14	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GTACGCCTACAGCAGGCCCGCGG	PTPN21	ENSG00000070778	0.16325143102801326	[2,2]	[2,1]	3	hSpCas9	positive selection	3082570
88517214	88517237		-	24336571	A375	resistance to PLX after 7 days	ACAACAAGCAAAATCAGCGCCGG	PTPN21	ENSG00000070778	0.04862253993490273	[3,2]	[3,3]	1	hSpCas9	positive selection	3138798
88517143	88517166		-	24336571	A375	resistance to PLX after 7 days	TTGGAACCTACCGTCTATTTTGG	PTPN21	ENSG00000070778	-0.011579473587984834	[5,4]	[5,4]	0	hSpCas9	positive selection	3138799
88517214	88517237		-	24336571	A375	resistance to PLX after 14 days	ACAACAAGCAAAATCAGCGCCGG	PTPN21	ENSG00000070778	0.29233319187838447	[2,4]	[2,1]	3	hSpCas9	positive selection	3196591
88517143	88517166		-	24336571	A375	resistance to PLX after 14 days	TTGGAACCTACCGTCTATTTTGG	PTPN21	ENSG00000070778	0.35009626197480626	[6,3]	[2,2]	3	hSpCas9	positive selection	3196592
88517214	88517237		-	24336571	A375	viability after 7 days	ACAACAAGCAAAATCAGCGCCGG	PTPN21	ENSG00000070778	-1.2966505594198026	[9]	[3,2]	-9	hSpCas9	negative selection	3254384
88517143	88517166		-	24336571	A375	viability after 7 days	TTGGAACCTACCGTCTATTTTGG	PTPN21	ENSG00000070778	0.3983932057757573	[3]	[5,4]	6	hSpCas9	negative selection	3254385
88517214	88517237		-	24336571	A375	viability after 14 days	ACAACAAGCAAAATCAGCGCCGG	PTPN21	ENSG00000070778	-1.1258247387528628	[9]	[2,4]	-8	hSpCas9	negative selection	3312177
88517143	88517166		-	24336571	A375	viability after 14 days	TTGGAACCTACCGTCTATTTTGG	PTPN21	ENSG00000070778	0.41777188909395413	[3]	[6,3]	5	hSpCas9	negative selection	3312178
88479952	88479975	14	+	26780180	HT29	viability (Avana library 4 designs)	CTGGCTGTAGACCAGCGCCGCGG	PTPN21	ENSG00000070778	0.243050047457232	[]	[]	0	hSpCas9	negative selection	3452960
88480175	88480198	14	+	26780180	HT29	viability (Avana library 4 designs)	GGGTTGGACGACATCGGCGAGGG	PTPN21	ENSG00000070778	0.305376323276673	[]	[]	1	hSpCas9	negative selection	3452961
88479969	88479992	14	-	26780180	HT29	viability (Avana library 4 designs)	GTACGCCTACAGCAGGCCCGCGG	PTPN21	ENSG00000070778	1.33631295325729	[]	[]	5	hSpCas9	negative selection	3452962
88479969	88479992	14	-	26780180	A375	viability (Avana lentiCRISPRv2)	GTACGCCTACAGCAGGCCCGCGG	PTPN21	ENSG00000070778	7.53161079399402	[]	[]	9	hSpCas9	negative selection	3549585
88479952	88479975	14	+	26780180	A375	viability (Avana lentiCRISPRv2)	CTGGCTGTAGACCAGCGCCGCGG	PTPN21	ENSG00000070778	6.24068633605468	[]	[]	9	hSpCas9	negative selection	3549586
88480175	88480198	14	+	26780180	A375	viability (Avana lentiCRISPRv2)	GGGTTGGACGACATCGGCGAGGG	PTPN21	ENSG00000070778	1.79650466513619	[]	[]	2	hSpCas9	negative selection	3549587
88479841	88479864	14	-	26780180	A375	viability (Avana lentiCRISPRv2)	CCTACCCCTACCCTGCCGAGCGG	PTPN21	ENSG00000070778	1.92679350602896	[]	[]	2	hSpCas9	negative selection	3549588
88517214	88517237	14	-	26780180	A375	viability (Avana lentiCRISPRv2)	ACAACAAGCAAAATCAGCGCCGG	PTPN21	ENSG00000070778	-4.33576688822769	[]	[]	-5	hSpCas9	negative selection	3549589
88479969	88479992	14	-	26780180	A375	viability (Avana lentiGuide)	GTACGCCTACAGCAGGCCCGCGG	PTPN21	ENSG00000070778	1.38336347298679	[]	[]	1	hSpCas9	negative selection	3658244
88479952	88479975	14	+	26780180	A375	viability (Avana lentiGuide)	CTGGCTGTAGACCAGCGCCGCGG	PTPN21	ENSG00000070778	3.78348875362592	[]	[]	3	hSpCas9	negative selection	3658245
88480175	88480198	14	+	26780180	A375	viability (Avana lentiGuide)	GGGTTGGACGACATCGGCGAGGG	PTPN21	ENSG00000070778	-1.84939069983783	[]	[]	-3	hSpCas9	negative selection	3658246
88479841	88479864	14	-	26780180	A375	viability (Avana lentiGuide)	CCTACCCCTACCCTGCCGAGCGG	PTPN21	ENSG00000070778	0.207185646399809	[]	[]	0	hSpCas9	negative selection	3658247
88517214	88517237	14	-	26780180	A375	viability (Avana lentiGuide)	ACAACAAGCAAAATCAGCGCCGG	PTPN21	ENSG00000070778	3.28795373655418	[]	[]	3	hSpCas9	negative selection	3658248
88479969	88479992	14	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GTACGCCTACAGCAGGCCCGCGG	PTPN21	ENSG00000070778	0.16877422371191747	[4]	[3,5]	4	hSpCas9	positive selection	3766851
88479952	88479975	14	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CTGGCTGTAGACCAGCGCCGCGG	PTPN21	ENSG00000070778	0.32634442366181216	[3]	[5,4]	8	hSpCas9	positive selection	3766852
88480175	88480198	14	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGGTTGGACGACATCGGCGAGGG	PTPN21	ENSG00000070778	0.25939987115102664	[5]	[6,6]	7	hSpCas9	positive selection	3766853
88479841	88479864	14	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CCTACCCCTACCCTGCCGAGCGG	PTPN21	ENSG00000070778	0.038072582190037785	[3]	[3,3]	0	hSpCas9	positive selection	3766854
88517214	88517237	14	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ACAACAAGCAAAATCAGCGCCGG	PTPN21	ENSG00000070778	-0.5782771082719175	[5]	[3,2]	-7	hSpCas9	positive selection	3766855
88479969	88479992	14	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GTACGCCTACAGCAGGCCCGCGG	PTPN21	ENSG00000070778	0.0037551954292153467	[4]	[2,4]	0	hSpCas9	positive selection	3875458
88479952	88479975	14	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CTGGCTGTAGACCAGCGCCGCGG	PTPN21	ENSG00000070778	-0.11267753027605189	[5]	[3,4]	-1	hSpCas9	positive selection	3875459
88480175	88480198	14	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGGTTGGACGACATCGGCGAGGG	PTPN21	ENSG00000070778	0.2490997271440473	[6]	[6,6]	6	hSpCas9	positive selection	3875460
88479841	88479864	14	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CCTACCCCTACCCTGCCGAGCGG	PTPN21	ENSG00000070778	0.06590020717385853	[5]	[3,5]	1	hSpCas9	positive selection	3875461
88517214	88517237	14	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ACAACAAGCAAAATCAGCGCCGG	PTPN21	ENSG00000070778	-0.5389544923045246	[5]	[5,0]	-6	hSpCas9	positive selection	3875462
88517214	88517237	14	-	26780180	A375	viability	ACAACAAGCAAAATCAGCGCCGG	PTPN21	ENSG00000070778	1.51914499134359	[]	[]	8	hSpCas9	negative selection	3985872
88517143	88517166	14	-	26780180	A375	viability	TTGGAACCTACCGTCTATTTTGG	PTPN21	ENSG00000070778	0.337639869147142	[]	[]	0	hSpCas9	negative selection	3985873
88517214	88517237	14	-	26780180	HT29	viability (GeCKOv2 library)	ACAACAAGCAAAATCAGCGCCGG	PTPN21	ENSG00000070778	1.34076757918131	[]	[]	6	hSpCas9	negative selection	4093838
88517143	88517166	14	-	26780180	HT29	viability (GeCKOv2 library)	TTGGAACCTACCGTCTATTTTGG	PTPN21	ENSG00000070778	0.197443778132685	[]	[]	0	hSpCas9	negative selection	4093839
88517214	88517237	14	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	ACAACAAGCAAAATCAGCGCCGG	PTPN21	ENSG00000070778	-0.2628466314285487	[1]	[0,0]	-6	hSpCas9	positive selection	4164079
88517143	88517166	14	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TTGGAACCTACCGTCTATTTTGG	PTPN21	ENSG00000070778	-0.22712814685988364	[3]	[2,1]	-5	hSpCas9	positive selection	4164082
88517214	88517237	14	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	ACAACAAGCAAAATCAGCGCCGG	PTPN21	ENSG00000070778	-0.5513782608615819	[3]	[1,0,0,0]	-7	hSpCas9	positive selection	4228101
88517143	88517166	14	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TTGGAACCTACCGTCTATTTTGG	PTPN21	ENSG00000070778	1.0223895876785716	[4]	[3,2,1,4]	7	hSpCas9	positive selection	4228104
88517214	88517237	14	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ACAACAAGCAAAATCAGCGCCGG	PTPN21	ENSG00000070778	-0.0428119915790931	[3]	[3,2]	-1	hSpCas9	positive selection	4293089
88517143	88517166	14	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TTGGAACCTACCGTCTATTTTGG	PTPN21	ENSG00000070778	0.5167095570383026	[3]	[4,4]	9	hSpCas9	positive selection	4293090
88480003	88480025	14	+	27760321	OCIAML3	viability	GTTGAGGTTTCGCAGCGAGTGG	PTPN21	ENSG00000070778	-0.026195164651651393	[711,687]	[489,601]	0	hSpCas9	negative selection	4431897
88480108	88480130	14	+	27760321	OCIAML3	viability	TATCACGGCGCTGTGCCGATGG	PTPN21	ENSG00000070778	-0.12142982068541358	[668,619]	[439,493]	-1	hSpCas9	negative selection	4431898
88480163	88480185	14	-	27760321	OCIAML3	viability	CGTCCAACCCTAGCATCACCGG	PTPN21	ENSG00000070778	-0.18369332454107698	[508,450]	[253,428]	-2	hSpCas9	negative selection	4431899
88480256	88480278	14	-	27760321	OCIAML3	viability	TCAACGGTCGGATCCGTAATGG	PTPN21	ENSG00000070778	-0.20293454639904152	[235,211]	[115,198]	-2	hSpCas9	negative selection	4431900
88485109	88485131	14	+	27760321	OCIAML3	viability	CATTATAGTGCAACTGCGGTGG	PTPN21	ENSG00000070778	0.7193033540006961	[439,383]	[293,835]	8	hSpCas9	negative selection	4431901
88480003	88480025	14	+	27760321	OCIAML2	viability	GTTGAGGTTTCGCAGCGAGTGG	PTPN21	ENSG00000070778	0.31911266592213483	[711,687]	[592,858]	4	hSpCas9	negative selection	4515360
88480108	88480130	14	+	27760321	OCIAML2	viability	TATCACGGCGCTGTGCCGATGG	PTPN21	ENSG00000070778	-0.03703809357908805	[668,619]	[430,609]	0	hSpCas9	negative selection	4515361
88480163	88480185	14	-	27760321	OCIAML2	viability	CGTCCAACCCTAGCATCACCGG	PTPN21	ENSG00000070778	-0.01095991048854579	[508,450]	[300,494]	0	hSpCas9	negative selection	4515362
88480256	88480278	14	-	27760321	OCIAML2	viability	TCAACGGTCGGATCCGTAATGG	PTPN21	ENSG00000070778	0.10829667194858505	[235,211]	[198,189]	1	hSpCas9	negative selection	4515363
88485109	88485131	14	+	27760321	OCIAML2	viability	CATTATAGTGCAACTGCGGTGG	PTPN21	ENSG00000070778	-0.2795397899506665	[439,383]	[238,319]	-3	hSpCas9	negative selection	4515364
88480003	88480025	14	+	27760321	MV411	viability	GTTGAGGTTTCGCAGCGAGTGG	PTPN21	ENSG00000070778	0.1975146177262983	[711,687]	[409,711]	1	hSpCas9	negative selection	4598823
88480108	88480130	14	+	27760321	MV411	viability	TATCACGGCGCTGTGCCGATGG	PTPN21	ENSG00000070778	0.4172921790002381	[668,619]	[633,468]	3	hSpCas9	negative selection	4598824
88480163	88480185	14	-	27760321	MV411	viability	CGTCCAACCCTAGCATCACCGG	PTPN21	ENSG00000070778	-0.3544123187305397	[508,450]	[180,346]	-3	hSpCas9	negative selection	4598825
88480256	88480278	14	-	27760321	MV411	viability	TCAACGGTCGGATCCGTAATGG	PTPN21	ENSG00000070778	-0.7504487286048749	[235,211]	[48,145]	-5	hSpCas9	negative selection	4598826
88485109	88485131	14	+	27760321	MV411	viability	CATTATAGTGCAACTGCGGTGG	PTPN21	ENSG00000070778	-0.5066049671307659	[439,383]	[106,316]	-4	hSpCas9	negative selection	4598827
88480003	88480025	14	+	27760321	HL60	viability	GTTGAGGTTTCGCAGCGAGTGG	PTPN21	ENSG00000070778	0.5523748099474208	[711,687]	[794,887]	6	hSpCas9	negative selection	4682286
88480108	88480130	14	+	27760321	HL60	viability	TATCACGGCGCTGTGCCGATGG	PTPN21	ENSG00000070778	0.017131184883246275	[668,619]	[643,414]	0	hSpCas9	negative selection	4682287
88480163	88480185	14	-	27760321	HL60	viability	CGTCCAACCCTAGCATCACCGG	PTPN21	ENSG00000070778	0.10835029291028306	[508,450]	[387,457]	1	hSpCas9	negative selection	4682288
88480256	88480278	14	-	27760321	HL60	viability	TCAACGGTCGGATCCGTAATGG	PTPN21	ENSG00000070778	0.6729883140189796	[235,211]	[271,311]	7	hSpCas9	negative selection	4682289
88485109	88485131	14	+	27760321	HL60	viability	CATTATAGTGCAACTGCGGTGG	PTPN21	ENSG00000070778	-0.06731963641488313	[439,383]	[302,338]	0	hSpCas9	negative selection	4682290
88480003	88480025	14	+	27760321	HT1080	viability	GTTGAGGTTTCGCAGCGAGTGG	PTPN21	ENSG00000070778	0.03737910470712813	[687,536]	[121,390]	0	hSpCas9	negative selection	4765749
88480108	88480130	14	+	27760321	HT1080	viability	TATCACGGCGCTGTGCCGATGG	PTPN21	ENSG00000070778	-0.6291414299925777	[619,483]	[145,137]	-3	hSpCas9	negative selection	4765750
88480163	88480185	14	-	27760321	HT1080	viability	CGTCCAACCCTAGCATCACCGG	PTPN21	ENSG00000070778	-0.33584785439838405	[450,351]	[120,132]	-1	hSpCas9	negative selection	4765751
88480256	88480278	14	-	27760321	HT1080	viability	TCAACGGTCGGATCCGTAATGG	PTPN21	ENSG00000070778	0.1617830759811718	[211,165]	[120,43]	0	hSpCas9	negative selection	4765752
88485109	88485131	14	+	27760321	HT1080	viability	CATTATAGTGCAACTGCGGTGG	PTPN21	ENSG00000070778	-0.8201435205018138	[383,299]	[6,153]	-3	hSpCas9	negative selection	4765753
88480003	88480025	14	+	27760321	HT29	viability after 7 days	GTTGAGGTTTCGCAGCGAGTGG	PTPN21	ENSG00000070778	-0.1183204416028153	[687,536]	[857,536,796]	-2	hSpCas9	negative selection	4849212
88480108	88480130	14	+	27760321	HT29	viability after 7 days	TATCACGGCGCTGTGCCGATGG	PTPN21	ENSG00000070778	-0.20567008753561083	[619,483]	[856,380,640]	-3	hSpCas9	negative selection	4849213
88480163	88480185	14	-	27760321	HT29	viability after 7 days	CGTCCAACCCTAGCATCACCGG	PTPN21	ENSG00000070778	0.19185282328678113	[450,351]	[562,539,658]	3	hSpCas9	negative selection	4849214
88480256	88480278	14	-	27760321	HT29	viability after 7 days	TCAACGGTCGGATCCGTAATGG	PTPN21	ENSG00000070778	0.23147586558249933	[211,165]	[291,387,179]	3	hSpCas9	negative selection	4849215
88485109	88485131	14	+	27760321	HT29	viability after 7 days	CATTATAGTGCAACTGCGGTGG	PTPN21	ENSG00000070778	-0.08534570580250157	[383,299]	[418,616,213]	-1	hSpCas9	negative selection	4849216
88480003	88480025	14	+	27760321	HT29	viability after 25 days	GTTGAGGTTTCGCAGCGAGTGG	PTPN21	ENSG00000070778	-0.20480848344671265	[687,536]	[560,586,683]	-2	hSpCas9	negative selection	4932675
88480108	88480130	14	+	27760321	HT29	viability after 25 days	TATCACGGCGCTGTGCCGATGG	PTPN21	ENSG00000070778	0.10616815623091147	[619,483]	[740,664,619]	1	hSpCas9	negative selection	4932676
88480163	88480185	14	-	27760321	HT29	viability after 25 days	CGTCCAACCCTAGCATCACCGG	PTPN21	ENSG00000070778	-0.06829740633324916	[450,351]	[417,254,663]	0	hSpCas9	negative selection	4932677
88480256	88480278	14	-	27760321	HT29	viability after 25 days	TCAACGGTCGGATCCGTAATGG	PTPN21	ENSG00000070778	0.859470427829797	[211,165]	[323,442,414]	8	hSpCas9	negative selection	4932678
88485109	88485131	14	+	27760321	HT29	viability after 25 days	CATTATAGTGCAACTGCGGTGG	PTPN21	ENSG00000070778	-0.24699190758740092	[383,299]	[254,306,441]	-3	hSpCas9	negative selection	4932679
88480003	88480025	14	+	27760321	HT29	viability after 22 days	GTTGAGGTTTCGCAGCGAGTGG	PTPN21	ENSG00000070778	-0.07484195373045255	[687,536]	[593,642,782]	-1	hSpCas9	negative selection	5016138
88480108	88480130	14	+	27760321	HT29	viability after 22 days	TATCACGGCGCTGTGCCGATGG	PTPN21	ENSG00000070778	0.1811175899954871	[619,483]	[774,785,606]	1	hSpCas9	negative selection	5016139
88480163	88480185	14	-	27760321	HT29	viability after 22 days	CGTCCAACCCTAGCATCACCGG	PTPN21	ENSG00000070778	0.10037898123709596	[450,351]	[471,363,658]	1	hSpCas9	negative selection	5016140
88480256	88480278	14	-	27760321	HT29	viability after 22 days	TCAACGGTCGGATCCGTAATGG	PTPN21	ENSG00000070778	0.46454500966883094	[211,165]	[258,324,321]	5	hSpCas9	negative selection	5016141
88485109	88485131	14	+	27760321	HT29	viability after 22 days	CATTATAGTGCAACTGCGGTGG	PTPN21	ENSG00000070778	0.0032221958395631245	[383,299]	[286,379,525]	0	hSpCas9	negative selection	5016142
88480003	88480025	14	+	27760321	HT29	viability after 19 days	GTTGAGGTTTCGCAGCGAGTGG	PTPN21	ENSG00000070778	-0.01689417685922101	[687,536]	[815,727,550]	0	hSpCas9	negative selection	5099601
88480108	88480130	14	+	27760321	HT29	viability after 19 days	TATCACGGCGCTGTGCCGATGG	PTPN21	ENSG00000070778	0.3711163159011036	[619,483]	[1057,913,513]	3	hSpCas9	negative selection	5099602
88480163	88480185	14	-	27760321	HT29	viability after 19 days	CGTCCAACCCTAGCATCACCGG	PTPN21	ENSG00000070778	0.13363060866192647	[450,351]	[603,375,539]	1	hSpCas9	negative selection	5099603
88480256	88480278	14	-	27760321	HT29	viability after 19 days	TCAACGGTCGGATCCGTAATGG	PTPN21	ENSG00000070778	0.5338166798478987	[211,165]	[194,486,246]	5	hSpCas9	negative selection	5099604
88485109	88485131	14	+	27760321	HT29	viability after 19 days	CATTATAGTGCAACTGCGGTGG	PTPN21	ENSG00000070778	-0.6572872871385246	[383,299]	[199,454,89]	-5	hSpCas9	negative selection	5099605
88480003	88480025	14	+	27760321	HT29	viability after 16 days	GTTGAGGTTTCGCAGCGAGTGG	PTPN21	ENSG00000070778	0.14671589107998306	[687,536]	[661,935,663]	1	hSpCas9	negative selection	5183064
88480108	88480130	14	+	27760321	HT29	viability after 16 days	TATCACGGCGCTGTGCCGATGG	PTPN21	ENSG00000070778	0.2619822094799543	[619,483]	[779,713,731]	3	hSpCas9	negative selection	5183065
88480163	88480185	14	-	27760321	HT29	viability after 16 days	CGTCCAACCCTAGCATCACCGG	PTPN21	ENSG00000070778	0.38979524880336414	[450,351]	[799,416,572]	4	hSpCas9	negative selection	5183066
88480256	88480278	14	-	27760321	HT29	viability after 16 days	TCAACGGTCGGATCCGTAATGG	PTPN21	ENSG00000070778	0.424280563262308	[211,165]	[270,251,327]	5	hSpCas9	negative selection	5183067
88485109	88485131	14	+	27760321	HT29	viability after 16 days	CATTATAGTGCAACTGCGGTGG	PTPN21	ENSG00000070778	-0.1678959448594784	[383,299]	[337,284,399]	-2	hSpCas9	negative selection	5183068
88480003	88480025	14	+	27760321	HT29	viability after 13 days	GTTGAGGTTTCGCAGCGAGTGG	PTPN21	ENSG00000070778	-0.0782886059281358	[687,536]	[472,558,968]	-1	hSpCas9	negative selection	5266527
88480108	88480130	14	+	27760321	HT29	viability after 13 days	TATCACGGCGCTGTGCCGATGG	PTPN21	ENSG00000070778	0.15241882655668648	[619,483]	[630,565,924]	1	hSpCas9	negative selection	5266528
88480163	88480185	14	-	27760321	HT29	viability after 13 days	CGTCCAACCCTAGCATCACCGG	PTPN21	ENSG00000070778	0.47054030797176827	[450,351]	[617,584,727]	6	hSpCas9	negative selection	5266529
88480256	88480278	14	-	27760321	HT29	viability after 13 days	TCAACGGTCGGATCCGTAATGG	PTPN21	ENSG00000070778	0.20763891094308629	[211,165]	[158,399,203]	2	hSpCas9	negative selection	5266530
88485109	88485131	14	+	27760321	HT29	viability after 13 days	CATTATAGTGCAACTGCGGTGG	PTPN21	ENSG00000070778	-0.06390382367813184	[383,299]	[182,624,333]	-1	hSpCas9	negative selection	5266531
88480003	88480025	14	+	27760321	HT29	viability after 10 days	GTTGAGGTTTCGCAGCGAGTGG	PTPN21	ENSG00000070778	-0.27273983506217625	[687,536]	[594,510,785]	-3	hSpCas9	negative selection	5349990
88480108	88480130	14	+	27760321	HT29	viability after 10 days	TATCACGGCGCTGTGCCGATGG	PTPN21	ENSG00000070778	0.28704432929911927	[619,483]	[888,745,883]	4	hSpCas9	negative selection	5349991
88480163	88480185	14	-	27760321	HT29	viability after 10 days	CGTCCAACCCTAGCATCACCGG	PTPN21	ENSG00000070778	0.2660170622015319	[450,351]	[426,474,895]	3	hSpCas9	negative selection	5349992
88480256	88480278	14	-	27760321	HT29	viability after 10 days	TCAACGGTCGGATCCGTAATGG	PTPN21	ENSG00000070778	0.127135259048626	[211,165]	[477,153,140]	1	hSpCas9	negative selection	5349993
88485109	88485131	14	+	27760321	HT29	viability after 10 days	CATTATAGTGCAACTGCGGTGG	PTPN21	ENSG00000070778	-0.23099599930027326	[383,299]	[622,237,229]	-3	hSpCas9	negative selection	5349994
88480003	88480025	14	+	27760321	MOLM13	viability	GTTGAGGTTTCGCAGCGAGTGG	PTPN21	ENSG00000070778	1.1868519292768032	[711,687]	[1165,674]	8	hSpCas9	negative selection	5433453
88480108	88480130	14	+	27760321	MOLM13	viability	TATCACGGCGCTGTGCCGATGG	PTPN21	ENSG00000070778	0.7388533046294998	[668,619]	[432,754]	5	hSpCas9	negative selection	5433454
88480163	88480185	14	-	27760321	MOLM13	viability	CGTCCAACCCTAGCATCACCGG	PTPN21	ENSG00000070778	0.32851460469848215	[508,450]	[352,327]	2	hSpCas9	negative selection	5433455
88480256	88480278	14	-	27760321	MOLM13	viability	TCAACGGTCGGATCCGTAATGG	PTPN21	ENSG00000070778	2.1487792734294895	[235,211]	[1133,70]	9	hSpCas9	negative selection	5433456
88485109	88485131	14	+	27760321	MOLM13	viability	CATTATAGTGCAACTGCGGTGG	PTPN21	ENSG00000070778	0.35982081989609493	[439,383]	[470,149]	2	hSpCas9	negative selection	5433457
88554594	88554617	14	-	27661255	K562	viability	GGCGGCTGGCCCGAGCGGTGGGG	PTPN21	ENSG00000070778	0.09575369984883597	[216,322]	[284,180]	3	dCas9-KRAB	negative selection	5505243
88517214	88517237	14	-	27260156	BXPC3	viability	ACAACAAGCAAAATCAGCGCCGG	PTPN21	ENSG00000070778	-0.3207686734324373	[870]	[629,766,688,847]	-6	hSpCas9	negative selection	5565549
88517143	88517166	14	-	27260156	BXPC3	viability	TTGGAACCTACCGTCTATTTTGG	PTPN21	ENSG00000070778	0.6498862848287768	[742]	[1175,1174,1238,1293]	9	hSpCas9	negative selection	5565550
88517214	88517237	14	-	27260156	A673	viability	ACAACAAGCAAAATCAGCGCCGG	PTPN21	ENSG00000070778	-0.008484389682088977	[870]	[1178,850,904,1255]	0	hSpCas9	negative selection	5686800
88517143	88517166	14	-	27260156	A673	viability	TTGGAACCTACCGTCTATTTTGG	PTPN21	ENSG00000070778	0.5369944760061409	[742]	[1440,1276,1189,1284]	9	hSpCas9	negative selection	5686801
88517214	88517237	14	-	27260156	A375	viability	ACAACAAGCAAAATCAGCGCCGG	PTPN21	ENSG00000070778	-0.05765157471493643	[870]	[924,1195,1141,705]	-1	hSpCas9	negative selection	5808051
88517143	88517166	14	-	27260156	A375	viability	TTGGAACCTACCGTCTATTTTGG	PTPN21	ENSG00000070778	0.89753447103494	[742]	[1519,1979,1623,1410]	9	hSpCas9	negative selection	5808052
88517214	88517237	14	-	27260156	COLO741	viability	ACAACAAGCAAAATCAGCGCCGG	PTPN21	ENSG00000070778	-0.0221727199890146	[870]	[1332,1225,770]	0	hSpCas9	negative selection	5929302
88517143	88517166	14	-	27260156	COLO741	viability	TTGGAACCTACCGTCTATTTTGG	PTPN21	ENSG00000070778	0.4681826783587977	[742]	[1587,1230,1152]	8	hSpCas9	negative selection	5929303
88517214	88517237	14	-	27260156	CAL120	viability	ACAACAAGCAAAATCAGCGCCGG	PTPN21	ENSG00000070778	-0.24426083142697252	[870]	[978,726,1045]	-4	hSpCas9	negative selection	6050553
88517143	88517166	14	-	27260156	CAL120	viability	TTGGAACCTACCGTCTATTTTGG	PTPN21	ENSG00000070778	0.7078723872410326	[742]	[1694,1196,1662]	9	hSpCas9	negative selection	6050554
88517214	88517237	14	-	27260156	CADOES1	viability	ACAACAAGCAAAATCAGCGCCGG	PTPN21	ENSG00000070778	-0.05272549506798685	[870]	[656,1083,679,700]	-1	hSpCas9	negative selection	6171804
88517143	88517166	14	-	27260156	CADOES1	viability	TTGGAACCTACCGTCTATTTTGG	PTPN21	ENSG00000070778	0.7925024354105439	[742]	[1216,1302,1118,1146]	9	hSpCas9	negative selection	6171805
88517214	88517237	14	-	27260156	EWS502	viability	ACAACAAGCAAAATCAGCGCCGG	PTPN21	ENSG00000070778	-0.24270899922494904	[870]	[844,727,830,700]	-4	hSpCas9	negative selection	6293055
88517143	88517166	14	-	27260156	EWS502	viability	TTGGAACCTACCGTCTATTTTGG	PTPN21	ENSG00000070778	0.793807220258639	[742]	[1509,1195,1310,1427]	9	hSpCas9	negative selection	6293056
88517214	88517237	14	-	27260156	EW8	viability	ACAACAAGCAAAATCAGCGCCGG	PTPN21	ENSG00000070778	-0.13612921444634074	[870]	[762,613,604,604]	-3	hSpCas9	negative selection	6414306
88517143	88517166	14	-	27260156	EW8	viability	TTGGAACCTACCGTCTATTTTGG	PTPN21	ENSG00000070778	0.6581167961171062	[742]	[1157,889,877,906]	9	hSpCas9	negative selection	6414307
88517214	88517237	14	-	27260156	CORL105	viability	ACAACAAGCAAAATCAGCGCCGG	PTPN21	ENSG00000070778	-0.03171023536940254	[870]	[1079,1043,1096,786]	0	hSpCas9	negative selection	6535557
88517143	88517166	14	-	27260156	CORL105	viability	TTGGAACCTACCGTCTATTTTGG	PTPN21	ENSG00000070778	0.5060253226465823	[742]	[1246,1241,1166,1273]	8	hSpCas9	negative selection	6535558
88517214	88517237	14	-	27260156	HS294T	viability	ACAACAAGCAAAATCAGCGCCGG	PTPN21	ENSG00000070778	-0.5925624517531851	[870]	[190,223,230,254]	-7	hSpCas9	negative selection	6656808
88517143	88517166	14	-	27260156	HS294T	viability	TTGGAACCTACCGTCTATTTTGG	PTPN21	ENSG00000070778	0.951594951902188	[742]	[708,414,537,546]	9	hSpCas9	negative selection	6656809
88517214	88517237	14	-	27260156	HCC44	viability	ACAACAAGCAAAATCAGCGCCGG	PTPN21	ENSG00000070778	-0.5068910543885354	[870]	[676,696,737,661]	-6	hSpCas9	negative selection	6778059
88517143	88517166	14	-	27260156	HCC44	viability	TTGGAACCTACCGTCTATTTTGG	PTPN21	ENSG00000070778	0.4518322847402525	[742]	[1027,1009,1628,1016]	7	hSpCas9	negative selection	6778060
88517214	88517237	14	-	27260156	G402	viability	ACAACAAGCAAAATCAGCGCCGG	PTPN21	ENSG00000070778	-0.29502550094414437	[870]	[559,1095,426,1324]	-4	hSpCas9	negative selection	6899310
88517143	88517166	14	-	27260156	G402	viability	TTGGAACCTACCGTCTATTTTGG	PTPN21	ENSG00000070778	1.052276043358456	[742]	[1026,2103,2412,1859]	9	hSpCas9	negative selection	6899311
88517214	88517237	14	-	27260156	L33	viability	ACAACAAGCAAAATCAGCGCCGG	PTPN21	ENSG00000070778	-0.27985290394211293	[870]	[752,265,460,732]	-6	hSpCas9	negative selection	7020561
88517143	88517166	14	-	27260156	L33	viability	TTGGAACCTACCGTCTATTTTGG	PTPN21	ENSG00000070778	0.6127614396879157	[742]	[1229,414,643,1272]	9	hSpCas9	negative selection	7020562
88517214	88517237	14	-	27260156	K562	viability	ACAACAAGCAAAATCAGCGCCGG	PTPN21	ENSG00000070778	0.19570538123417325	[870]	[1071,883,876,736]	2	hSpCas9	negative selection	7141812
88517143	88517166	14	-	27260156	K562	viability	TTGGAACCTACCGTCTATTTTGG	PTPN21	ENSG00000070778	0.5877659945940521	[742]	[1340,627,1195,823]	7	hSpCas9	negative selection	7141813
88517214	88517237	14	-	27260156	HT29	viability	ACAACAAGCAAAATCAGCGCCGG	PTPN21	ENSG00000070778	0.012726884490181112	[870]	[1036,1122,1063,1045]	0	hSpCas9	negative selection	7263063
88517143	88517166	14	-	27260156	HT29	viability	TTGGAACCTACCGTCTATTTTGG	PTPN21	ENSG00000070778	0.5492237740782986	[742]	[1377,1664,1127,1159]	9	hSpCas9	negative selection	7263064
88517214	88517237	14	-	27260156	MHHES1	viability	ACAACAAGCAAAATCAGCGCCGG	PTPN21	ENSG00000070778	0.04752598722395851	[870]	[901,1419,906,864]	0	hSpCas9	negative selection	7384314
88517143	88517166	14	-	27260156	MHHES1	viability	TTGGAACCTACCGTCTATTTTGG	PTPN21	ENSG00000070778	0.5265171558051838	[742]	[1674,1476,924,876]	8	hSpCas9	negative selection	7384315
88517214	88517237	14	-	27260156	MEWO	viability	ACAACAAGCAAAATCAGCGCCGG	PTPN21	ENSG00000070778	0.18171119730163532	[870]	[1078,828,894]	4	hSpCas9	negative selection	7505565
88517143	88517166	14	-	27260156	MEWO	viability	TTGGAACCTACCGTCTATTTTGG	PTPN21	ENSG00000070778	0.4656395814489469	[742]	[995,1066,822]	8	hSpCas9	negative selection	7505566
88517214	88517237	14	-	27260156	LNCAPCLONEFGC	viability	ACAACAAGCAAAATCAGCGCCGG	PTPN21	ENSG00000070778	-0.22767727245849612	[870]	[581,676,731,713]	-4	hSpCas9	negative selection	7626816
88517143	88517166	14	-	27260156	LNCAPCLONEFGC	viability	TTGGAACCTACCGTCTATTTTGG	PTPN21	ENSG00000070778	0.6885834603486465	[742]	[899,1035,1292,1146]	9	hSpCas9	negative selection	7626817
88517214	88517237	14	-	27260156	PANC0327	viability	ACAACAAGCAAAATCAGCGCCGG	PTPN21	ENSG00000070778	-0.03921809312636604	[870]	[675,692,761,881]	0	hSpCas9	negative selection	7748067
88517143	88517166	14	-	27260156	PANC0327	viability	TTGGAACCTACCGTCTATTTTGG	PTPN21	ENSG00000070778	0.43762407692850624	[742]	[1187,551,1097,805]	6	hSpCas9	negative selection	7748068
88517214	88517237	14	-	27260156	NCIH2009	viability	ACAACAAGCAAAATCAGCGCCGG	PTPN21	ENSG00000070778	0.011318988255328066	[870]	[1296,1081,1314]	0	hSpCas9	negative selection	7869318
88517143	88517166	14	-	27260156	NCIH2009	viability	TTGGAACCTACCGTCTATTTTGG	PTPN21	ENSG00000070778	0.8799766700856866	[742]	[2347,1665,1804]	9	hSpCas9	negative selection	7869319
88517214	88517237	14	-	27260156	NCIH1373	viability	ACAACAAGCAAAATCAGCGCCGG	PTPN21	ENSG00000070778	0.03827124979852503	[870]	[1039,1341,794,206]	0	hSpCas9	negative selection	7990569
88517143	88517166	14	-	27260156	NCIH1373	viability	TTGGAACCTACCGTCTATTTTGG	PTPN21	ENSG00000070778	1.2599756556755732	[742]	[3351,1560,1700,418]	9	hSpCas9	negative selection	7990570
88517214	88517237	14	-	27260156	PATU8902	viability	ACAACAAGCAAAATCAGCGCCGG	PTPN21	ENSG00000070778	0.31534943614859634	[870]	[1140,935,1952,1933]	3	hSpCas9	negative selection	8111820
88517143	88517166	14	-	27260156	PATU8902	viability	TTGGAACCTACCGTCTATTTTGG	PTPN21	ENSG00000070778	0.9268535049046156	[742]	[2219,1779,1135,3059]	8	hSpCas9	negative selection	8111821
88517214	88517237	14	-	27260156	PANC1	viability	ACAACAAGCAAAATCAGCGCCGG	PTPN21	ENSG00000070778	-0.5493140034188104	[870]	[457,767,431,442]	-7	hSpCas9	negative selection	8233071
88517143	88517166	14	-	27260156	PANC1	viability	TTGGAACCTACCGTCTATTTTGG	PTPN21	ENSG00000070778	0.5676055337054957	[742]	[1036,1384,710,752]	8	hSpCas9	negative selection	8233072
88517214	88517237	14	-	27260156	PANC0813	viability	ACAACAAGCAAAATCAGCGCCGG	PTPN21	ENSG00000070778	-0.27915151355437384	[870]	[958,632,1059,736]	-4	hSpCas9	negative selection	8354322
88517143	88517166	14	-	27260156	PANC0813	viability	TTGGAACCTACCGTCTATTTTGG	PTPN21	ENSG00000070778	0.6673799919680428	[742]	[1495,1344,1427,1288]	9	hSpCas9	negative selection	8354323
88517214	88517237	14	-	27260156	RDES	viability	ACAACAAGCAAAATCAGCGCCGG	PTPN21	ENSG00000070778	-0.28762330124355007	[870]	[727,756,832,990]	-5	hSpCas9	negative selection	8475573
88517143	88517166	14	-	27260156	RDES	viability	TTGGAACCTACCGTCTATTTTGG	PTPN21	ENSG00000070778	0.9103252459125462	[742]	[1313,1558,1742,1871]	9	hSpCas9	negative selection	8475574
88517214	88517237	14	-	27260156	PC3	viability	ACAACAAGCAAAATCAGCGCCGG	PTPN21	ENSG00000070778	-0.0874584680316639	[870]	[549,931,1361,653]	-2	hSpCas9	negative selection	8596824
88517143	88517166	14	-	27260156	PC3	viability	TTGGAACCTACCGTCTATTTTGG	PTPN21	ENSG00000070778	0.4429020603556455	[742]	[647,805,2125,950]	8	hSpCas9	negative selection	8596825
88517214	88517237	14	-	27260156	PATU8988T	viability	ACAACAAGCAAAATCAGCGCCGG	PTPN21	ENSG00000070778	-0.13093192699448553	[870]	[668,865,733,818]	-2	hSpCas9	negative selection	8718075
88517143	88517166	14	-	27260156	PATU8988T	viability	TTGGAACCTACCGTCTATTTTGG	PTPN21	ENSG00000070778	0.4690849065225091	[742]	[836,1182,822,1165]	7	hSpCas9	negative selection	8718076
88517214	88517237	14	-	27260156	T47D	viability	ACAACAAGCAAAATCAGCGCCGG	PTPN21	ENSG00000070778	-0.31549016462652946	[870]	[879,642,868,885]	-6	hSpCas9	negative selection	8839326
88517143	88517166	14	-	27260156	T47D	viability	TTGGAACCTACCGTCTATTTTGG	PTPN21	ENSG00000070778	0.569286986431742	[742]	[1179,1305,1268,1382]	9	hSpCas9	negative selection	8839327
88517214	88517237	14	-	27260156	SU8686	viability	ACAACAAGCAAAATCAGCGCCGG	PTPN21	ENSG00000070778	-0.16198523280244403	[870]	[590,816,798,912]	-3	hSpCas9	negative selection	8960577
88517143	88517166	14	-	27260156	SU8686	viability	TTGGAACCTACCGTCTATTTTGG	PTPN21	ENSG00000070778	0.7131977271634067	[742]	[1015,1010,1350,1550]	9	hSpCas9	negative selection	8960578
88517214	88517237	14	-	27260156	SKES1	viability	ACAACAAGCAAAATCAGCGCCGG	PTPN21	ENSG00000070778	-0.10484587186123162	[870]	[756,756,939,759]	-2	hSpCas9	negative selection	9081828
88517143	88517166	14	-	27260156	SKES1	viability	TTGGAACCTACCGTCTATTTTGG	PTPN21	ENSG00000070778	0.8315940029825739	[742]	[1692,1364,1306,993]	9	hSpCas9	negative selection	9081829
88517214	88517237	14	-	27260156	TOV112D	viability	ACAACAAGCAAAATCAGCGCCGG	PTPN21	ENSG00000070778	-0.12292088611135399	[870]	[860,1071,656,687]	-2	hSpCas9	negative selection	9203079
88517143	88517166	14	-	27260156	TOV112D	viability	TTGGAACCTACCGTCTATTTTGG	PTPN21	ENSG00000070778	0.3810396593288585	[742]	[943,1486,595,972]	7	hSpCas9	negative selection	9203080
88517214	88517237	14	-	27260156	TC71	viability	ACAACAAGCAAAATCAGCGCCGG	PTPN21	ENSG00000070778	0.010415662364207434	[870]	[901,951,823,1097]	0	hSpCas9	negative selection	9324330
88517143	88517166	14	-	27260156	TC71	viability	TTGGAACCTACCGTCTATTTTGG	PTPN21	ENSG00000070778	0.5320219422655206	[742]	[1182,1109,1164,1146]	9	hSpCas9	negative selection	9324331
88517214	88517237	14	-	27260156	TC32	viability	ACAACAAGCAAAATCAGCGCCGG	PTPN21	ENSG00000070778	-0.15644566566848483	[870]	[784,529,858,815]	-3	hSpCas9	negative selection	9445581
88517143	88517166	14	-	27260156	TC32	viability	TTGGAACCTACCGTCTATTTTGG	PTPN21	ENSG00000070778	0.5500034742849049	[742]	[1032,670,1306,1209]	8	hSpCas9	negative selection	9445582
88485075	88485098	14	-	27869803	HPAFII	viability after 27 days	GAACCATATGCTTCTTCCCAAGG	PTPN21	ENSG00000070778	1.1396613684159962	[92]	[26,174,NaN]	8	hSpCas9	negative selection	9552654
88485806	88485829	14	-	27869803	HPAFII	viability after 27 days	TCACAGTGAACCCAATCAGGAGG	PTPN21	ENSG00000070778	-0.027021265595230493	[181]	[124,67,NaN]	0	hSpCas9	negative selection	9552655
88517073	88517096	14	+	27869803	HPAFII	viability after 27 days	ACGGCATGTAATTTCTCACCTGG	PTPN21	ENSG00000070778	-0.20272756797002756	[199]	[56,119,NaN]	-1	hSpCas9	negative selection	9552656
88550360	88550383	14	+	27869803	HPAFII	viability after 27 days	TGCTGGACACCGTGTAGCGCCGG	PTPN21	ENSG00000070778	-1.257228784152588	[464]	[68,129,NaN]	-7	hSpCas9	negative selection	9552657
88485075	88485098	14	-	27869803	HPAFII	viability after 15 days	GAACCATATGCTTCTTCCCAAGG	PTPN21	ENSG00000070778	0.4123601390938707	[92]	[161,114,NaN]	5	hSpCas9	negative selection	9635103
88485806	88485829	14	-	27869803	HPAFII	viability after 15 days	TCACAGTGAACCCAATCAGGAGG	PTPN21	ENSG00000070778	0.26890708388282614	[181]	[358,158,NaN]	3	hSpCas9	negative selection	9635104
88517073	88517096	14	+	27869803	HPAFII	viability after 15 days	ACGGCATGTAATTTCTCACCTGG	PTPN21	ENSG00000070778	-0.19130410879141957	[199]	[215,170,NaN]	-2	hSpCas9	negative selection	9635105
88550360	88550383	14	+	27869803	HPAFII	viability after 15 days	TGCTGGACACCGTGTAGCGCCGG	PTPN21	ENSG00000070778	-0.42317787058736855	[464]	[405,351,NaN]	-5	hSpCas9	negative selection	9635106
88485075	88485098	14	-	27869803	ASPC1	viability after 36 days	GAACCATATGCTTCTTCCCAAGG	PTPN21	ENSG00000070778	0.6055754052858089	[323]	[228,329,4]	6	hSpCas9	negative selection	9717552
88485806	88485829	14	-	27869803	ASPC1	viability after 36 days	TCACAGTGAACCCAATCAGGAGG	PTPN21	ENSG00000070778	0.5142448541601524	[581]	[210,455,210]	5	hSpCas9	negative selection	9717553
88517073	88517096	14	+	27869803	ASPC1	viability after 36 days	ACGGCATGTAATTTCTCACCTGG	PTPN21	ENSG00000070778	1.034421985122909	[545]	[266,655,261]	8	hSpCas9	negative selection	9717554
88550360	88550383	14	+	27869803	ASPC1	viability after 36 days	TGCTGGACACCGTGTAGCGCCGG	PTPN21	ENSG00000070778	-0.20271534224179755	[1238]	[193,660,272]	-2	hSpCas9	negative selection	9717555
88485075	88485098	14	-	27869803	PATU8988S	viability after 35 days	GAACCATATGCTTCTTCCCAAGG	PTPN21	ENSG00000070778	-0.44735754167572617	[285]	[73,94,NaN]	-4	hSpCas9	negative selection	9800001
88485806	88485829	14	-	27869803	PATU8988S	viability after 35 days	TCACAGTGAACCCAATCAGGAGG	PTPN21	ENSG00000070778	0.5454620683328999	[456]	[324,211,NaN]	6	hSpCas9	negative selection	9800002
88517073	88517096	14	+	27869803	PATU8988S	viability after 35 days	ACGGCATGTAATTTCTCACCTGG	PTPN21	ENSG00000070778	0.8071058504802192	[561]	[411,379,NaN]	8	hSpCas9	negative selection	9800003
88550360	88550383	14	+	27869803	PATU8988S	viability after 35 days	TGCTGGACACCGTGTAGCGCCGG	PTPN21	ENSG00000070778	0.6808178970402008	[1204]	[550,1005,NaN]	7	hSpCas9	negative selection	9800004
88485075	88485098	14	-	27869803	PATU8988S	viability after 31 days	GAACCATATGCTTCTTCCCAAGG	PTPN21	ENSG00000070778	-0.5252818499660538	[285]	[69,90,NaN]	-5	hSpCas9	negative selection	9882450
88485806	88485829	14	-	27869803	PATU8988S	viability after 31 days	TCACAGTGAACCCAATCAGGAGG	PTPN21	ENSG00000070778	0.556261870569463	[456]	[241,300,NaN]	6	hSpCas9	negative selection	9882451
88517073	88517096	14	+	27869803	PATU8988S	viability after 31 days	ACGGCATGTAATTTCTCACCTGG	PTPN21	ENSG00000070778	0.7153361110033453	[561]	[231,540,NaN]	8	hSpCas9	negative selection	9882452
88550360	88550383	14	+	27869803	PATU8988S	viability after 31 days	TGCTGGACACCGTGTAGCGCCGG	PTPN21	ENSG00000070778	0.5503934738502991	[1204]	[433,1046,NaN]	6	hSpCas9	negative selection	9882453
88485075	88485098	14	-	27869803	HPAFII	viability after 35 days	GAACCATATGCTTCTTCCCAAGG	PTPN21	ENSG00000070778	0.6309565497062669	[92]	[7,145,NaN]	4	hSpCas9	negative selection	9964899
88485806	88485829	14	-	27869803	HPAFII	viability after 35 days	TCACAGTGAACCCAATCAGGAGG	PTPN21	ENSG00000070778	0.14526498135268223	[181]	[131,67,NaN]	0	hSpCas9	negative selection	9964900
88517073	88517096	14	+	27869803	HPAFII	viability after 35 days	ACGGCATGTAATTTCTCACCTGG	PTPN21	ENSG00000070778	-0.5934672886684362	[199]	[36,100,NaN]	-4	hSpCas9	negative selection	9964901
88550360	88550383	14	+	27869803	HPAFII	viability after 35 days	TGCTGGACACCGTGTAGCGCCGG	PTPN21	ENSG00000070778	-1.1602522890186777	[464]	[54,161,NaN]	-6	hSpCas9	negative selection	9964902
88485075	88485098	14	-	27869803	HPAFII	viability after 31 days	GAACCATATGCTTCTTCCCAAGG	PTPN21	ENSG00000070778	0.8463874218325341	[92]	[0,194,NaN]	6	hSpCas9	negative selection	10047348
88485806	88485829	14	-	27869803	HPAFII	viability after 31 days	TCACAGTGAACCCAATCAGGAGG	PTPN21	ENSG00000070778	-0.19510509758717942	[181]	[82,95,NaN]	-1	hSpCas9	negative selection	10047349
88517073	88517096	14	+	27869803	HPAFII	viability after 31 days	ACGGCATGTAATTTCTCACCTGG	PTPN21	ENSG00000070778	0.06603195646553278	[199]	[83,153,NaN]	0	hSpCas9	negative selection	10047350
88550360	88550383	14	+	27869803	HPAFII	viability after 31 days	TGCTGGACACCGTGTAGCGCCGG	PTPN21	ENSG00000070778	-0.32787062789655985	[464]	[138,282,NaN]	-2	hSpCas9	negative selection	10047351
88517214	88517237	14	-	28162770	P31FUJ	viability	ACAACAAGCAAAATCAGCGCCGG	PTPN21	ENSG00000070778	-0.14707233038849465	[97]	[103]	-1	hSpCas9	negative selection	10219815
88479848	88479871	14	+	28162770	P31FUJ	viability	GCAGGGTAGGGGTAGGGAGACGG	PTPN21	ENSG00000070778	-7.49019004710703	[152]	[0]	-9	hSpCas9	negative selection	10219816
88480049	88480072	14	-	28162770	P31FUJ	viability	GTGATGAAGCAGCTCAACAGGGG	PTPN21	ENSG00000070778	0.3285734759891617	[184]	[272]	3	hSpCas9	negative selection	10219817
88479366	88479389	14	-	28162770	P31FUJ	viability	GACACAGCGAGAAGGGCCGGAGG	PTPN21	ENSG00000070778	0.3310986807789478	[22]	[33]	3	hSpCas9	negative selection	10219818
88479267	88479290	14	-	28162770	P31FUJ	viability	GGAGGACGAGGACTTCGAGGAGG	PTPN21	ENSG00000070778	0.03539390653519425	[92]	[111]	0	hSpCas9	negative selection	10219819
88550237	88550260	14	-	28162770	P31FUJ	viability	CCAGAGGCTGGAGCTGCGGGAGG	PTPN21	ENSG00000070778	-1.2036558587548623	[97]	[49]	-7	hSpCas9	negative selection	10219820
88517162	88517185	14	-	28162770	P31FUJ	viability	GCAGCTGGATAAATATGCATTGG	PTPN21	ENSG00000070778	0.6032481506436911	[255]	[456]	7	hSpCas9	negative selection	10219821
88485803	88485826	14	-	28162770	P31FUJ	viability	CAGTGAACCCAATCAGGAGGAGG	PTPN21	ENSG00000070778	0.8060868089792164	[182]	[375]	8	hSpCas9	negative selection	10219822
88480175	88480198	14	+	28162770	P31FUJ	viability	GGGTTGGACGACATCGGCGAGGG	PTPN21	ENSG00000070778	0.3336709247399132	[444]	[658]	3	hSpCas9	negative selection	10219823
88517214	88517237	14	-	28162770	TF1	viability	ACAACAAGCAAAATCAGCGCCGG	PTPN21	ENSG00000070778	NaN	[NaN]	[27]	1	hSpCas9	negative selection	10389181
88479848	88479871	14	+	28162770	TF1	viability	GCAGGGTAGGGGTAGGGAGACGG	PTPN21	ENSG00000070778	NaN	[NaN]	[19]	1	hSpCas9	negative selection	10389182
88480049	88480072	14	-	28162770	TF1	viability	GTGATGAAGCAGCTCAACAGGGG	PTPN21	ENSG00000070778	NaN	[NaN]	[76]	1	hSpCas9	negative selection	10389183
88479366	88479389	14	-	28162770	TF1	viability	GACACAGCGAGAAGGGCCGGAGG	PTPN21	ENSG00000070778	NaN	[NaN]	[61]	1	hSpCas9	negative selection	10389184
88479267	88479290	14	-	28162770	TF1	viability	GGAGGACGAGGACTTCGAGGAGG	PTPN21	ENSG00000070778	NaN	[NaN]	[41]	1	hSpCas9	negative selection	10389185
88550237	88550260	14	-	28162770	TF1	viability	CCAGAGGCTGGAGCTGCGGGAGG	PTPN21	ENSG00000070778	NaN	[NaN]	[183]	1	hSpCas9	negative selection	10389186
88517162	88517185	14	-	28162770	TF1	viability	GCAGCTGGATAAATATGCATTGG	PTPN21	ENSG00000070778	NaN	[NaN]	[279]	1	hSpCas9	negative selection	10389187
88485803	88485826	14	-	28162770	TF1	viability	CAGTGAACCCAATCAGGAGGAGG	PTPN21	ENSG00000070778	NaN	[NaN]	[238]	1	hSpCas9	negative selection	10389188
88480175	88480198	14	+	28162770	TF1	viability	GGGTTGGACGACATCGGCGAGGG	PTPN21	ENSG00000070778	NaN	[NaN]	[516]	1	hSpCas9	negative selection	10389189
88517214	88517237	14	-	28162770	SKM1	viability	ACAACAAGCAAAATCAGCGCCGG	PTPN21	ENSG00000070778	-1.4849667107444349	[37]	[23]	-7	hSpCas9	negative selection	10558547
88479848	88479871	14	+	28162770	SKM1	viability	GCAGGGTAGGGGTAGGGAGACGG	PTPN21	ENSG00000070778	-2.376590549699643	[46]	[15]	-8	hSpCas9	negative selection	10558548
88480049	88480072	14	-	28162770	SKM1	viability	GTGATGAAGCAGCTCAACAGGGG	PTPN21	ENSG00000070778	0.26546114322833386	[55]	[118]	2	hSpCas9	negative selection	10558549
88479366	88479389	14	-	28162770	SKM1	viability	GACACAGCGAGAAGGGCCGGAGG	PTPN21	ENSG00000070778	-1.1115083152169905	[10]	[8]	-7	hSpCas9	negative selection	10558550
88479267	88479290	14	-	28162770	SKM1	viability	GGAGGACGAGGACTTCGAGGAGG	PTPN21	ENSG00000070778	-0.8220016980220055	[30]	[30]	-6	hSpCas9	negative selection	10558551
88550237	88550260	14	-	28162770	SKM1	viability	CCAGAGGCTGGAGCTGCGGGAGG	PTPN21	ENSG00000070778	1.8102665174775074	[19]	[123]	9	hSpCas9	negative selection	10558552
88517162	88517185	14	-	28162770	SKM1	viability	GCAGCTGGATAAATATGCATTGG	PTPN21	ENSG00000070778	-0.05229931744379937	[60]	[103]	0	hSpCas9	negative selection	10558553
88485803	88485826	14	-	28162770	SKM1	viability	CAGTGAACCCAATCAGGAGGAGG	PTPN21	ENSG00000070778	0.9634937900718592	[37]	[130]	8	hSpCas9	negative selection	10558554
88480175	88480198	14	+	28162770	SKM1	viability	GGGTTGGACGACATCGGCGAGGG	PTPN21	ENSG00000070778	1.1467473679935547	[69]	[273]	9	hSpCas9	negative selection	10558555
88517214	88517237	14	-	28162770	SKM1	viability	ACAACAAGCAAAATCAGCGCCGG	PTPN21	ENSG00000070778	-1.4849667107444349	[37]	[23]	-7	hSpCas9	negative selection	10727913
88479848	88479871	14	+	28162770	SKM1	viability	GCAGGGTAGGGGTAGGGAGACGG	PTPN21	ENSG00000070778	-2.376590549699643	[46]	[15]	-8	hSpCas9	negative selection	10727914
88480049	88480072	14	-	28162770	SKM1	viability	GTGATGAAGCAGCTCAACAGGGG	PTPN21	ENSG00000070778	0.26546114322833386	[55]	[118]	2	hSpCas9	negative selection	10727915
88479366	88479389	14	-	28162770	SKM1	viability	GACACAGCGAGAAGGGCCGGAGG	PTPN21	ENSG00000070778	-1.1115083152169905	[10]	[8]	-7	hSpCas9	negative selection	10727916
88479267	88479290	14	-	28162770	SKM1	viability	GGAGGACGAGGACTTCGAGGAGG	PTPN21	ENSG00000070778	-0.8220016980220055	[30]	[30]	-6	hSpCas9	negative selection	10727917
88550237	88550260	14	-	28162770	SKM1	viability	CCAGAGGCTGGAGCTGCGGGAGG	PTPN21	ENSG00000070778	1.8102665174775074	[19]	[123]	9	hSpCas9	negative selection	10727918
88517162	88517185	14	-	28162770	SKM1	viability	GCAGCTGGATAAATATGCATTGG	PTPN21	ENSG00000070778	-0.05229931744379937	[60]	[103]	0	hSpCas9	negative selection	10727919
88485803	88485826	14	-	28162770	SKM1	viability	CAGTGAACCCAATCAGGAGGAGG	PTPN21	ENSG00000070778	0.9634937900718592	[37]	[130]	8	hSpCas9	negative selection	10727920
88480175	88480198	14	+	28162770	SKM1	viability	GGGTTGGACGACATCGGCGAGGG	PTPN21	ENSG00000070778	1.1467473679935547	[69]	[273]	9	hSpCas9	negative selection	10727921
88517214	88517237	14	-	28162770	PL21	viability	ACAACAAGCAAAATCAGCGCCGG	PTPN21	ENSG00000070778	-1.5864567474014866	[137]	[19]	-7	hSpCas9	negative selection	10897279
88479848	88479871	14	+	28162770	PL21	viability	GCAGGGTAGGGGTAGGGAGACGG	PTPN21	ENSG00000070778	-1.607215307568284	[174]	[24]	-8	hSpCas9	negative selection	10897280
88480049	88480072	14	-	28162770	PL21	viability	GTGATGAAGCAGCTCAACAGGGG	PTPN21	ENSG00000070778	-0.384822886231836	[173]	[57]	-3	hSpCas9	negative selection	10897281
88479366	88479389	14	-	28162770	PL21	viability	GACACAGCGAGAAGGGCCGGAGG	PTPN21	ENSG00000070778	-0.7718460093410833	[50]	[12]	-5	hSpCas9	negative selection	10897282
88479267	88479290	14	-	28162770	PL21	viability	GGAGGACGAGGACTTCGAGGAGG	PTPN21	ENSG00000070778	-1.5963269914255476	[131]	[18]	-7	hSpCas9	negative selection	10897283
88550237	88550260	14	-	28162770	PL21	viability	CCAGAGGCTGGAGCTGCGGGAGG	PTPN21	ENSG00000070778	-1.0504038471612769	[137]	[28]	-6	hSpCas9	negative selection	10897284
88517162	88517185	14	-	28162770	PL21	viability	GCAGCTGGATAAATATGCATTGG	PTPN21	ENSG00000070778	-0.11455691116696659	[198]	[79]	-1	hSpCas9	negative selection	10897285
88485803	88485826	14	-	28162770	PL21	viability	CAGTGAACCCAATCAGGAGGAGG	PTPN21	ENSG00000070778	0.9278866786261477	[156]	[129]	7	hSpCas9	negative selection	10897286
88480175	88480198	14	+	28162770	PL21	viability	GGGTTGGACGACATCGGCGAGGG	PTPN21	ENSG00000070778	-0.5503407861513676	[285]	[84]	-4	hSpCas9	negative selection	10897287
88517214	88517237	14	-	28162770	P31FUJ	viability	ACAACAAGCAAAATCAGCGCCGG	PTPN21	ENSG00000070778	-0.14707233038849465	[97]	[103]	-1	hSpCas9	negative selection	11066645
88479848	88479871	14	+	28162770	P31FUJ	viability	GCAGGGTAGGGGTAGGGAGACGG	PTPN21	ENSG00000070778	-7.49019004710703	[152]	[0]	-9	hSpCas9	negative selection	11066646
88480049	88480072	14	-	28162770	P31FUJ	viability	GTGATGAAGCAGCTCAACAGGGG	PTPN21	ENSG00000070778	0.3285734759891617	[184]	[272]	3	hSpCas9	negative selection	11066647
88479366	88479389	14	-	28162770	P31FUJ	viability	GACACAGCGAGAAGGGCCGGAGG	PTPN21	ENSG00000070778	0.3310986807789478	[22]	[33]	3	hSpCas9	negative selection	11066648
88479267	88479290	14	-	28162770	P31FUJ	viability	GGAGGACGAGGACTTCGAGGAGG	PTPN21	ENSG00000070778	0.03539390653519425	[92]	[111]	0	hSpCas9	negative selection	11066649
88550237	88550260	14	-	28162770	P31FUJ	viability	CCAGAGGCTGGAGCTGCGGGAGG	PTPN21	ENSG00000070778	-1.2036558587548623	[97]	[49]	-7	hSpCas9	negative selection	11066650
88517162	88517185	14	-	28162770	P31FUJ	viability	GCAGCTGGATAAATATGCATTGG	PTPN21	ENSG00000070778	0.6032481506436911	[255]	[456]	7	hSpCas9	negative selection	11066651
88485803	88485826	14	-	28162770	P31FUJ	viability	CAGTGAACCCAATCAGGAGGAGG	PTPN21	ENSG00000070778	0.8060868089792164	[182]	[375]	8	hSpCas9	negative selection	11066652
88480175	88480198	14	+	28162770	P31FUJ	viability	GGGTTGGACGACATCGGCGAGGG	PTPN21	ENSG00000070778	0.3336709247399132	[444]	[658]	3	hSpCas9	negative selection	11066653
88517214	88517237	14	-	28162770	OCIAML5	viability	ACAACAAGCAAAATCAGCGCCGG	PTPN21	ENSG00000070778	-0.31601367062378716	[59]	[86]	-2	hSpCas9	negative selection	11236011
88479848	88479871	14	+	28162770	OCIAML5	viability	GCAGGGTAGGGGTAGGGAGACGG	PTPN21	ENSG00000070778	-5.495922760638722	[149]	[5]	-9	hSpCas9	negative selection	11236012
88480049	88480072	14	-	28162770	OCIAML5	viability	GTGATGAAGCAGCTCAACAGGGG	PTPN21	ENSG00000070778	-0.37672856131733923	[81]	[113]	-3	hSpCas9	negative selection	11236013
88479366	88479389	14	-	28162770	OCIAML5	viability	GACACAGCGAGAAGGGCCGGAGG	PTPN21	ENSG00000070778	1.8667516765919498	[11]	[78]	9	hSpCas9	negative selection	11236014
88479267	88479290	14	-	28162770	OCIAML5	viability	GGAGGACGAGGACTTCGAGGAGG	PTPN21	ENSG00000070778	-1.3788144576398573	[84]	[58]	-7	hSpCas9	negative selection	11236015
88550237	88550260	14	-	28162770	OCIAML5	viability	CCAGAGGCTGGAGCTGCGGGAGG	PTPN21	ENSG00000070778	1.2303955893279759	[33]	[143]	9	hSpCas9	negative selection	11236016
88517162	88517185	14	-	28162770	OCIAML5	viability	GCAGCTGGATAAATATGCATTGG	PTPN21	ENSG00000070778	-0.26412021170401945	[160]	[241]	-2	hSpCas9	negative selection	11236017
88485803	88485826	14	-	28162770	OCIAML5	viability	CAGTGAACCCAATCAGGAGGAGG	PTPN21	ENSG00000070778	1.214235799504158	[100]	[422]	9	hSpCas9	negative selection	11236018
88480175	88480198	14	+	28162770	OCIAML5	viability	GGGTTGGACGACATCGGCGAGGG	PTPN21	ENSG00000070778	0.35216648135361084	[216]	[499]	3	hSpCas9	negative selection	11236019
88517214	88517237	14	-	28162770	EOL1	viability	ACAACAAGCAAAATCAGCGCCGG	PTPN21	ENSG00000070778	-1.4299849887487555	[178]	[34]	-7	hSpCas9	negative selection	11405377
88479848	88479871	14	+	28162770	EOL1	viability	GCAGGGTAGGGGTAGGGAGACGG	PTPN21	ENSG00000070778	-2.4058419020650237	[170]	[16]	-8	hSpCas9	negative selection	11405378
88480049	88480072	14	-	28162770	EOL1	viability	GTGATGAAGCAGCTCAACAGGGG	PTPN21	ENSG00000070778	1.3971625464261934	[306]	[425]	9	hSpCas9	negative selection	11405379
88479366	88479389	14	-	28162770	EOL1	viability	GACACAGCGAGAAGGGCCGGAGG	PTPN21	ENSG00000070778	-0.4653987467454792	[75]	[28]	-3	hSpCas9	negative selection	11405380
88479267	88479290	14	-	28162770	EOL1	viability	GGAGGACGAGGACTTCGAGGAGG	PTPN21	ENSG00000070778	-1.0593325630661885	[177]	[44]	-6	hSpCas9	negative selection	11405381
88550237	88550260	14	-	28162770	EOL1	viability	CCAGAGGCTGGAGCTGCGGGAGG	PTPN21	ENSG00000070778	-0.2755918429187857	[192]	[83]	-2	hSpCas9	negative selection	11405382
88517162	88517185	14	-	28162770	EOL1	viability	GCAGCTGGATAAATATGCATTGG	PTPN21	ENSG00000070778	-0.3226699288004844	[253]	[106]	-2	hSpCas9	negative selection	11405383
88485803	88485826	14	-	28162770	EOL1	viability	CAGTGAACCCAATCAGGAGGAGG	PTPN21	ENSG00000070778	0.6628066827582613	[222]	[185]	6	hSpCas9	negative selection	11405384
88480175	88480198	14	+	28162770	EOL1	viability	GGGTTGGACGACATCGGCGAGGG	PTPN21	ENSG00000070778	0.7636115533554768	[359]	[321]	6	hSpCas9	negative selection	11405385
88517214	88517237	14	-	28162770	MOLM13	viability	ACAACAAGCAAAATCAGCGCCGG	PTPN21	ENSG00000070778	0.46788938154457893	[200]	[200]	3	hSpCas9	negative selection	11574743
88479848	88479871	14	+	28162770	MOLM13	viability	GCAGGGTAGGGGTAGGGAGACGG	PTPN21	ENSG00000070778	-5.0743686682223395	[232]	[4]	-9	hSpCas9	negative selection	11574744
88480049	88480072	14	-	28162770	MOLM13	viability	GTGATGAAGCAGCTCAACAGGGG	PTPN21	ENSG00000070778	0.1969280599391563	[291]	[241]	1	hSpCas9	negative selection	11574745
88479366	88479389	14	-	28162770	MOLM13	viability	GACACAGCGAGAAGGGCCGGAGG	PTPN21	ENSG00000070778	-0.14508749534617382	[77]	[50]	-1	hSpCas9	negative selection	11574746
88479267	88479290	14	-	28162770	MOLM13	viability	GGAGGACGAGGACTTCGAGGAGG	PTPN21	ENSG00000070778	-0.9623505243779353	[158]	[58]	-5	hSpCas9	negative selection	11574747
88550237	88550260	14	-	28162770	MOLM13	viability	CCAGAGGCTGGAGCTGCGGGAGG	PTPN21	ENSG00000070778	1.7819979719726418	[110]	[275]	9	hSpCas9	negative selection	11574748
88517162	88517185	14	-	28162770	MOLM13	viability	GCAGCTGGATAAATATGCATTGG	PTPN21	ENSG00000070778	-0.8853428332607931	[395]	[154]	-5	hSpCas9	negative selection	11574749
88485803	88485826	14	-	28162770	MOLM13	viability	CAGTGAACCCAATCAGGAGGAGG	PTPN21	ENSG00000070778	0.4398750053749824	[259]	[254]	3	hSpCas9	negative selection	11574750
88480175	88480198	14	+	28162770	MOLM13	viability	GGGTTGGACGACATCGGCGAGGG	PTPN21	ENSG00000070778	-0.9850775733665871	[500]	[182]	-5	hSpCas9	negative selection	11574751
88517214	88517237	14	-	28162770	HEL	viability	ACAACAAGCAAAATCAGCGCCGG	PTPN21	ENSG00000070778	0.016197227527801283	[175]	[113]	0	hSpCas9	negative selection	11744109
88479848	88479871	14	+	28162770	HEL	viability	GCAGGGTAGGGGTAGGGAGACGG	PTPN21	ENSG00000070778	-7.064620300080525	[208]	[0]	-9	hSpCas9	negative selection	11744110
88480049	88480072	14	-	28162770	HEL	viability	GTGATGAAGCAGCTCAACAGGGG	PTPN21	ENSG00000070778	0.9842071132833644	[175]	[222]	8	hSpCas9	negative selection	11744111
88479366	88479389	14	-	28162770	HEL	viability	GACACAGCGAGAAGGGCCGGAGG	PTPN21	ENSG00000070778	0.18039561794315673	[61]	[44]	1	hSpCas9	negative selection	11744112
88479267	88479290	14	-	28162770	HEL	viability	GGAGGACGAGGACTTCGAGGAGG	PTPN21	ENSG00000070778	1.5033357753349406	[113]	[206]	9	hSpCas9	negative selection	11744113
88550237	88550260	14	-	28162770	HEL	viability	CCAGAGGCTGGAGCTGCGGGAGG	PTPN21	ENSG00000070778	-0.23742139799363982	[126]	[68]	-2	hSpCas9	negative selection	11744114
88517162	88517185	14	-	28162770	HEL	viability	GCAGCTGGATAAATATGCATTGG	PTPN21	ENSG00000070778	-1.1325548808249488	[266]	[77]	-6	hSpCas9	negative selection	11744115
88485803	88485826	14	-	28162770	HEL	viability	CAGTGAACCCAATCAGGAGGAGG	PTPN21	ENSG00000070778	0.23275456044779846	[189]	[142]	2	hSpCas9	negative selection	11744116
88480175	88480198	14	+	28162770	HEL	viability	GGGTTGGACGACATCGGCGAGGG	PTPN21	ENSG00000070778	0.16456174390950318	[396]	[284]	1	hSpCas9	negative selection	11744117
88517214	88517237	14	-	28162770	MV411	viability	ACAACAAGCAAAATCAGCGCCGG	PTPN21	ENSG00000070778	-0.5180971955802018	[101]	[59]	-4	hSpCas9	negative selection	11913475
88479848	88479871	14	+	28162770	MV411	viability	GCAGGGTAGGGGTAGGGAGACGG	PTPN21	ENSG00000070778	-4.818651639674997	[133]	[3]	-9	hSpCas9	negative selection	11913476
88480049	88480072	14	-	28162770	MV411	viability	GTGATGAAGCAGCTCAACAGGGG	PTPN21	ENSG00000070778	-0.520892214292766	[154]	[90]	-4	hSpCas9	negative selection	11913477
88479366	88479389	14	-	28162770	MV411	viability	GACACAGCGAGAAGGGCCGGAGG	PTPN21	ENSG00000070778	0.24743755078277507	[37]	[37]	2	hSpCas9	negative selection	11913478
88479267	88479290	14	-	28162770	MV411	viability	GGAGGACGAGGACTTCGAGGAGG	PTPN21	ENSG00000070778	0.6151693352832625	[61]	[79]	5	hSpCas9	negative selection	11913479
88550237	88550260	14	-	28162770	MV411	viability	CCAGAGGCTGGAGCTGCGGGAGG	PTPN21	ENSG00000070778	-0.8340923347138229	[90]	[42]	-5	hSpCas9	negative selection	11913480
88517162	88517185	14	-	28162770	MV411	viability	GCAGCTGGATAAATATGCATTGG	PTPN21	ENSG00000070778	-0.030718142075681687	[210]	[173]	0	hSpCas9	negative selection	11913481
88485803	88485826	14	-	28162770	MV411	viability	CAGTGAACCCAATCAGGAGGAGG	PTPN21	ENSG00000070778	0.6071077396616888	[165]	[212]	5	hSpCas9	negative selection	11913482
88480175	88480198	14	+	28162770	MV411	viability	GGGTTGGACGACATCGGCGAGGG	PTPN21	ENSG00000070778	0.2035832611933478	[333]	[323]	1	hSpCas9	negative selection	11913483
88517214	88517237	14	-	28162770	MONOMAC1	viability	ACAACAAGCAAAATCAGCGCCGG	PTPN21	ENSG00000070778	-0.26213187528143866	[67]	[64]	-2	hSpCas9	negative selection	12082841
88479848	88479871	14	+	28162770	MONOMAC1	viability	GCAGGGTAGGGGTAGGGAGACGG	PTPN21	ENSG00000070778	-1.1768589651219235	[70]	[35]	-7	hSpCas9	negative selection	12082842
88480049	88480072	14	-	28162770	MONOMAC1	viability	GTGATGAAGCAGCTCAACAGGGG	PTPN21	ENSG00000070778	-0.18572153383171952	[126]	[127]	-2	hSpCas9	negative selection	12082843
88479366	88479389	14	-	28162770	MONOMAC1	viability	GACACAGCGAGAAGGGCCGGAGG	PTPN21	ENSG00000070778	1.0616974213406147	[27]	[66]	8	hSpCas9	negative selection	12082844
88479267	88479290	14	-	28162770	MONOMAC1	viability	GGAGGACGAGGACTTCGAGGAGG	PTPN21	ENSG00000070778	-0.5368868499441786	[80]	[63]	-4	hSpCas9	negative selection	12082845
88550237	88550260	14	-	28162770	MONOMAC1	viability	CCAGAGGCTGGAGCTGCGGGAGG	PTPN21	ENSG00000070778	0.07533542335357635	[76]	[92]	0	hSpCas9	negative selection	12082846
88517162	88517185	14	-	28162770	MONOMAC1	viability	GCAGCTGGATAAATATGCATTGG	PTPN21	ENSG00000070778	0.7221804982244003	[100]	[190]	7	hSpCas9	negative selection	12082847
88485803	88485826	14	-	28162770	MONOMAC1	viability	CAGTGAACCCAATCAGGAGGAGG	PTPN21	ENSG00000070778	0.675957876205126	[88]	[162]	6	hSpCas9	negative selection	12082848
88480175	88480198	14	+	28162770	MONOMAC1	viability	GGGTTGGACGACATCGGCGAGGG	PTPN21	ENSG00000070778	0.09330490476997555	[156]	[191]	0	hSpCas9	negative selection	12082849
88517214	88517237	14	-	28162770	OCIAML2	viability	ACAACAAGCAAAATCAGCGCCGG	PTPN21	ENSG00000070778	0.2926699167375074	[18]	[128]	3	hSpCas9	negative selection	12252207
88479848	88479871	14	+	28162770	OCIAML2	viability	GCAGGGTAGGGGTAGGGAGACGG	PTPN21	ENSG00000070778	-2.693022246578609	[20]	[17]	-9	hSpCas9	negative selection	12252208
88480049	88480072	14	-	28162770	OCIAML2	viability	GTGATGAAGCAGCTCAACAGGGG	PTPN21	ENSG00000070778	-0.2768580818454811	[39]	[182]	-2	hSpCas9	negative selection	12252209
88479366	88479389	14	-	28162770	OCIAML2	viability	GACACAGCGAGAAGGGCCGGAGG	PTPN21	ENSG00000070778	-1.1487017303547988	[9]	[24]	-6	hSpCas9	negative selection	12252210
88479267	88479290	14	-	28162770	OCIAML2	viability	GGAGGACGAGGACTTCGAGGAGG	PTPN21	ENSG00000070778	-0.3486393008635509	[16]	[73]	-3	hSpCas9	negative selection	12252211
88550237	88550260	14	-	28162770	OCIAML2	viability	CCAGAGGCTGGAGCTGCGGGAGG	PTPN21	ENSG00000070778	0.8169467648544241	[16]	[165]	7	hSpCas9	negative selection	12252212
88517162	88517185	14	-	28162770	OCIAML2	viability	GCAGCTGGATAAATATGCATTGG	PTPN21	ENSG00000070778	0.02356721155581254	[40]	[230]	0	hSpCas9	negative selection	12252213
88485803	88485826	14	-	28162770	OCIAML2	viability	CAGTGAACCCAATCAGGAGGAGG	PTPN21	ENSG00000070778	0.0992257830887866	[31]	[189]	0	hSpCas9	negative selection	12252214
88480175	88480198	14	+	28162770	OCIAML2	viability	GGGTTGGACGACATCGGCGAGGG	PTPN21	ENSG00000070778	0.18946700553977458	[52]	[334]	1	hSpCas9	negative selection	12252215
88517214	88517237	14	-	28162770	OCIAML3	viability	ACAACAAGCAAAATCAGCGCCGG	PTPN21	ENSG00000070778	-0.1504009888485487	[24]	[67]	-1	hSpCas9	negative selection	12421573
88479848	88479871	14	+	28162770	OCIAML3	viability	GCAGGGTAGGGGTAGGGAGACGG	PTPN21	ENSG00000070778	-2.9445048874082964	[50]	[19]	-9	hSpCas9	negative selection	12421574
88480049	88480072	14	-	28162770	OCIAML3	viability	GTGATGAAGCAGCTCAACAGGGG	PTPN21	ENSG00000070778	0.43418925150648896	[37]	[154]	4	hSpCas9	negative selection	12421575
88479366	88479389	14	-	28162770	OCIAML3	viability	GACACAGCGAGAAGGGCCGGAGG	PTPN21	ENSG00000070778	-0.009045139603006902	[7]	[23]	0	hSpCas9	negative selection	12421576
88479267	88479290	14	-	28162770	OCIAML3	viability	GGAGGACGAGGACTTCGAGGAGG	PTPN21	ENSG00000070778	0.45910369613539936	[19]	[82]	4	hSpCas9	negative selection	12421577
88550237	88550260	14	-	28162770	OCIAML3	viability	CCAGAGGCTGGAGCTGCGGGAGG	PTPN21	ENSG00000070778	0.21334728173344086	[23]	[83]	2	hSpCas9	negative selection	12421578
88517162	88517185	14	-	28162770	OCIAML3	viability	GCAGCTGGATAAATATGCATTGG	PTPN21	ENSG00000070778	-0.05795474008395346	[59]	[173]	0	hSpCas9	negative selection	12421579
88485803	88485826	14	-	28162770	OCIAML3	viability	CAGTGAACCCAATCAGGAGGAGG	PTPN21	ENSG00000070778	0.9249573016227528	[40]	[234]	7	hSpCas9	negative selection	12421580
88480175	88480198	14	+	28162770	OCIAML3	viability	GGGTTGGACGACATCGGCGAGGG	PTPN21	ENSG00000070778	-0.1978067830581749	[105]	[278]	-1	hSpCas9	negative selection	12421581