Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:22827
• Symbol:PUF60
• Description:poly(U) binding splicing factor 60

DataSource: http://genomecrispr.dkfz.de/#!/results/PUF60

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
143818256	143818279	8	+	26472758	Jiyoye	viability	GGGGACCTCATACTCCACGAAGG	PUF60	ENSG00000179950	-3.7627496199364394	[35]	[1]	-9	hSpCas9	negative selection	131401
143805263	143805286	CHR_HSCHR8_3_CTG7	+	26472758	Jiyoye	viability	GGGGACCTCATACTCCACGAAGG	PUF60	ENSG00000274081	-3.7627496199364394	[35]	[1]	-9	hSpCas9	negative selection	131402
143821596	143821619	8	-	26472758	Jiyoye	viability	GCAGCAGCTCACCAACCTGCAGG	PUF60	ENSG00000179950	-1.7303281422440615	[87]	[19]	-8	hSpCas9	negative selection	131403
143808603	143808626	CHR_HSCHR8_3_CTG7	-	26472758	Jiyoye	viability	GCAGCAGCTCACCAACCTGCAGG	PUF60	ENSG00000274081	-1.7303281422440615	[87]	[19]	-8	hSpCas9	negative selection	131404
143816909	143816932	8	-	26472758	Jiyoye	viability	GAAGCTGCTCCGCAAGCAGGAGG	PUF60	ENSG00000179950	-0.17778711921528245	[8]	[5]	-1	hSpCas9	negative selection	131405
143803916	143803939	CHR_HSCHR8_3_CTG7	-	26472758	Jiyoye	viability	GAAGCTGCTCCGCAAGCAGGAGG	PUF60	ENSG00000274081	-0.17778711921528245	[8]	[5]	-1	hSpCas9	negative selection	131406
143808867	143808890	CHR_HSCHR8_3_CTG7	-	26472758	Jiyoye	viability	AGAGCACAGCCGCCAAGCTGGGG	PUF60	ENSG00000274081	0.40717538150587274	[0]	[0]	3	hSpCas9	negative selection	131407
143821860	143821883	8	-	26472758	Jiyoye	viability	AGAGCACAGCCGCCAAGCTGGGG	PUF60	ENSG00000179950	0.40717538150587274	[0]	[0]	3	hSpCas9	negative selection	131408
143821829	143821852	8	-	26472758	Jiyoye	viability	CCTGACGCCCGAGCAGCAGGAGG	PUF60	ENSG00000179950	-0.5928246184941266	[35]	[17]	-4	hSpCas9	negative selection	131409
143808836	143808859	CHR_HSCHR8_3_CTG7	-	26472758	Jiyoye	viability	CCTGACGCCCGAGCAGCAGGAGG	PUF60	ENSG00000274081	-0.5928246184941266	[35]	[17]	-4	hSpCas9	negative selection	131410
143817702	143817725	8	-	26472758	Jiyoye	viability	GGGTGGCCAGTACTTGCGGGTGG	PUF60	ENSG00000179950	-4.3477121206575955	[26]	[0]	-9	hSpCas9	negative selection	131411
143804709	143804732	CHR_HSCHR8_3_CTG7	-	26472758	Jiyoye	viability	GGGTGGCCAGTACTTGCGGGTGG	PUF60	ENSG00000274081	-4.3477121206575955	[26]	[0]	-9	hSpCas9	negative selection	131412
143804627	143804650	CHR_HSCHR8_3_CTG7	+	26472758	Jiyoye	viability	GCAGCTGCCACAGCAGCGGCAGG	PUF60	ENSG00000274081	0.40717538150587274	[0]	[0]	3	hSpCas9	negative selection	131413
143817620	143817643	8	+	26472758	Jiyoye	viability	GCAGCTGCCACAGCAGCGGCAGG	PUF60	ENSG00000179950	0.40717538150587274	[0]	[0]	3	hSpCas9	negative selection	131414
143804092	143804115	CHR_HSCHR8_3_CTG7	+	26472758	Jiyoye	viability	GGGTTCACCACTCCCACCGAGGG	PUF60	ENSG00000274081	-1.15986521121802	[79]	[26]	-7	hSpCas9	negative selection	131415
143817085	143817108	8	+	26472758	Jiyoye	viability	GGGTTCACCACTCCCACCGAGGG	PUF60	ENSG00000179950	-1.15986521121802	[79]	[26]	-7	hSpCas9	negative selection	131416
143821668	143821691	8	-	26472758	Jiyoye	viability	TCAGGCCAAGAAGTACGCCATGG	PUF60	ENSG00000179950	-3.490945004474913	[163]	[10]	-9	hSpCas9	negative selection	131417
143808675	143808698	CHR_HSCHR8_3_CTG7	-	26472758	Jiyoye	viability	TCAGGCCAAGAAGTACGCCATGG	PUF60	ENSG00000274081	-3.490945004474913	[163]	[10]	-9	hSpCas9	negative selection	131418
143808651	143808674	CHR_HSCHR8_3_CTG7	-	26472758	Jiyoye	viability	GCAGAGCATCAAGAGTGTGCTGG	PUF60	ENSG00000274081	-5.361008943271052	[326]	[5]	-9	hSpCas9	negative selection	131419
143821644	143821667	8	-	26472758	Jiyoye	viability	GCAGAGCATCAAGAGTGTGCTGG	PUF60	ENSG00000179950	-5.361008943271052	[326]	[5]	-9	hSpCas9	negative selection	131420
143818256	143818279	8	+	26472758	KBM7	viability	GGGGACCTCATACTCCACGAAGG	PUF60	ENSG00000179950	-3.286501436130598	[80,109]	[0,7]	-9	hSpCas9	negative selection	322519
143805263	143805286	CHR_HSCHR8_3_CTG7	+	26472758	KBM7	viability	GGGGACCTCATACTCCACGAAGG	PUF60	ENSG00000274081	-3.286501436130598	[80,109]	[0,7]	-9	hSpCas9	negative selection	322520
143821596	143821619	8	-	26472758	KBM7	viability	GCAGCAGCTCACCAACCTGCAGG	PUF60	ENSG00000179950	-0.8047318339248558	[832,665]	[182,215]	-6	hSpCas9	negative selection	322521
143808603	143808626	CHR_HSCHR8_3_CTG7	-	26472758	KBM7	viability	GCAGCAGCTCACCAACCTGCAGG	PUF60	ENSG00000274081	-0.8047318339248558	[832,665]	[182,215]	-6	hSpCas9	negative selection	322522
143816909	143816932	8	-	26472758	KBM7	viability	GAAGCTGCTCCGCAAGCAGGAGG	PUF60	ENSG00000179950	-1.2197513258989359	[484,395]	[98,78]	-7	hSpCas9	negative selection	322523
143803916	143803939	CHR_HSCHR8_3_CTG7	-	26472758	KBM7	viability	GAAGCTGCTCCGCAAGCAGGAGG	PUF60	ENSG00000274081	-1.2197513258989359	[484,395]	[98,78]	-7	hSpCas9	negative selection	322524
143808867	143808890	CHR_HSCHR8_3_CTG7	-	26472758	KBM7	viability	AGAGCACAGCCGCCAAGCTGGGG	PUF60	ENSG00000274081	-2.3172475847284404	[80,67]	[6,6]	-9	hSpCas9	negative selection	322525
143821860	143821883	8	-	26472758	KBM7	viability	AGAGCACAGCCGCCAAGCTGGGG	PUF60	ENSG00000179950	-2.3172475847284404	[80,67]	[6,6]	-9	hSpCas9	negative selection	322526
143821829	143821852	8	-	26472758	KBM7	viability	CCTGACGCCCGAGCAGCAGGAGG	PUF60	ENSG00000179950	-1.44347437563159	[497,393]	[65,85]	-7	hSpCas9	negative selection	322527
143808836	143808859	CHR_HSCHR8_3_CTG7	-	26472758	KBM7	viability	CCTGACGCCCGAGCAGCAGGAGG	PUF60	ENSG00000274081	-1.44347437563159	[497,393]	[65,85]	-7	hSpCas9	negative selection	322528
143817702	143817725	8	-	26472758	KBM7	viability	GGGTGGCCAGTACTTGCGGGTGG	PUF60	ENSG00000179950	0.21607310696281323	[202,122]	[167,14]	2	hSpCas9	negative selection	322529
143804709	143804732	CHR_HSCHR8_3_CTG7	-	26472758	KBM7	viability	GGGTGGCCAGTACTTGCGGGTGG	PUF60	ENSG00000274081	0.21607310696281323	[202,122]	[167,14]	2	hSpCas9	negative selection	322530
143804627	143804650	CHR_HSCHR8_3_CTG7	+	26472758	KBM7	viability	GCAGCTGCCACAGCAGCGGCAGG	PUF60	ENSG00000274081	0.48838885802848875	[1,3]	[0,2]	5	hSpCas9	negative selection	322531
143817620	143817643	8	+	26472758	KBM7	viability	GCAGCTGCCACAGCAGCGGCAGG	PUF60	ENSG00000179950	0.48838885802848875	[1,3]	[0,2]	5	hSpCas9	negative selection	322532
143804092	143804115	CHR_HSCHR8_3_CTG7	+	26472758	KBM7	viability	GGGTTCACCACTCCCACCGAGGG	PUF60	ENSG00000274081	-0.9447708385832772	[488,503]	[120,122]	-6	hSpCas9	negative selection	322533
143817085	143817108	8	+	26472758	KBM7	viability	GGGTTCACCACTCCCACCGAGGG	PUF60	ENSG00000179950	-0.9447708385832772	[488,503]	[120,122]	-6	hSpCas9	negative selection	322534
143821668	143821691	8	-	26472758	KBM7	viability	TCAGGCCAAGAAGTACGCCATGG	PUF60	ENSG00000179950	-2.58451026713466	[806,764]	[75,48]	-9	hSpCas9	negative selection	322535
143808675	143808698	CHR_HSCHR8_3_CTG7	-	26472758	KBM7	viability	TCAGGCCAAGAAGTACGCCATGG	PUF60	ENSG00000274081	-2.58451026713466	[806,764]	[75,48]	-9	hSpCas9	negative selection	322536
143808651	143808674	CHR_HSCHR8_3_CTG7	-	26472758	KBM7	viability	GCAGAGCATCAAGAGTGTGCTGG	PUF60	ENSG00000274081	-1.504207979696588	[926,967]	[173,143]	-8	hSpCas9	negative selection	322537
143821644	143821667	8	-	26472758	KBM7	viability	GCAGAGCATCAAGAGTGTGCTGG	PUF60	ENSG00000179950	-1.504207979696588	[926,967]	[173,143]	-8	hSpCas9	negative selection	322538
143818256	143818279	8	+	26472758	Raji	viability	GGGGACCTCATACTCCACGAAGG	PUF60	ENSG00000179950	-4.00114092140457	[68]	[0]	-9	hSpCas9	negative selection	513637
143805263	143805286	CHR_HSCHR8_3_CTG7	+	26472758	Raji	viability	GGGGACCTCATACTCCACGAAGG	PUF60	ENSG00000274081	-4.00114092140457	[68]	[0]	-9	hSpCas9	negative selection	513638
143821596	143821619	8	-	26472758	Raji	viability	GCAGCAGCTCACCAACCTGCAGG	PUF60	ENSG00000179950	-1.6961496757315961	[376]	[26]	-8	hSpCas9	negative selection	513639
143808603	143808626	CHR_HSCHR8_3_CTG7	-	26472758	Raji	viability	GCAGCAGCTCACCAACCTGCAGG	PUF60	ENSG00000274081	-1.6961496757315961	[376]	[26]	-8	hSpCas9	negative selection	513640
143816909	143816932	8	-	26472758	Raji	viability	GAAGCTGCTCCGCAAGCAGGAGG	PUF60	ENSG00000179950	-0.23978185101278576	[172]	[33]	-2	hSpCas9	negative selection	513641
143803916	143803939	CHR_HSCHR8_3_CTG7	-	26472758	Raji	viability	GAAGCTGCTCCGCAAGCAGGAGG	PUF60	ENSG00000274081	-0.23978185101278576	[172]	[33]	-2	hSpCas9	negative selection	513642
143808867	143808890	CHR_HSCHR8_3_CTG7	-	26472758	Raji	viability	AGAGCACAGCCGCCAAGCTGGGG	PUF60	ENSG00000274081	-1.3020074007641023	[84]	[7]	-7	hSpCas9	negative selection	513643
143821860	143821883	8	-	26472758	Raji	viability	AGAGCACAGCCGCCAAGCTGGGG	PUF60	ENSG00000179950	-1.3020074007641023	[84]	[7]	-7	hSpCas9	negative selection	513644
143821829	143821852	8	-	26472758	Raji	viability	CCTGACGCCCGAGCAGCAGGAGG	PUF60	ENSG00000179950	-2.569077319833053	[178]	[6]	-9	hSpCas9	negative selection	513645
143808836	143808859	CHR_HSCHR8_3_CTG7	-	26472758	Raji	viability	CCTGACGCCCGAGCAGCAGGAGG	PUF60	ENSG00000274081	-2.569077319833053	[178]	[6]	-9	hSpCas9	negative selection	513646
143817702	143817725	8	-	26472758	Raji	viability	GGGTGGCCAGTACTTGCGGGTGG	PUF60	ENSG00000179950	-1.9800793058767403	[50]	[2]	-8	hSpCas9	negative selection	513647
143804709	143804732	CHR_HSCHR8_3_CTG7	-	26472758	Raji	viability	GGGTGGCCAGTACTTGCGGGTGG	PUF60	ENSG00000274081	-1.9800793058767403	[50]	[2]	-8	hSpCas9	negative selection	513648
143804627	143804650	CHR_HSCHR8_3_CTG7	+	26472758	Raji	viability	GCAGCTGCCACAGCAGCGGCAGG	PUF60	ENSG00000274081	2.1073835353735992	[0]	[0]	9	hSpCas9	negative selection	513649
143817620	143817643	8	+	26472758	Raji	viability	GCAGCTGCCACAGCAGCGGCAGG	PUF60	ENSG00000179950	2.1073835353735992	[0]	[0]	9	hSpCas9	negative selection	513650
143804092	143804115	CHR_HSCHR8_3_CTG7	+	26472758	Raji	viability	GGGTTCACCACTCCCACCGAGGG	PUF60	ENSG00000274081	-1.5638113629916357	[292]	[22]	-8	hSpCas9	negative selection	513651
143817085	143817108	8	+	26472758	Raji	viability	GGGTTCACCACTCCCACCGAGGG	PUF60	ENSG00000179950	-1.5638113629916357	[292]	[22]	-8	hSpCas9	negative selection	513652
143821668	143821691	8	-	26472758	Raji	viability	TCAGGCCAAGAAGTACGCCATGG	PUF60	ENSG00000179950	-2.250168469244484	[327]	[15]	-9	hSpCas9	negative selection	513653
143808675	143808698	CHR_HSCHR8_3_CTG7	-	26472758	Raji	viability	TCAGGCCAAGAAGTACGCCATGG	PUF60	ENSG00000274081	-2.250168469244484	[327]	[15]	-9	hSpCas9	negative selection	513654
143808651	143808674	CHR_HSCHR8_3_CTG7	-	26472758	Raji	viability	GCAGAGCATCAAGAGTGTGCTGG	PUF60	ENSG00000274081	-2.5536819444333485	[505]	[19]	-9	hSpCas9	negative selection	513655
143821644	143821667	8	-	26472758	Raji	viability	GCAGAGCATCAAGAGTGTGCTGG	PUF60	ENSG00000179950	-2.5536819444333485	[505]	[19]	-9	hSpCas9	negative selection	513656
143818256	143818279	8	+	26472758	K562	viability	GGGGACCTCATACTCCACGAAGG	PUF60	ENSG00000179950	-2.5884712864982946	[113]	[15]	-8	hSpCas9	negative selection	704755
143805263	143805286	CHR_HSCHR8_3_CTG7	+	26472758	K562	viability	GGGGACCTCATACTCCACGAAGG	PUF60	ENSG00000274081	-2.5884712864982946	[113]	[15]	-8	hSpCas9	negative selection	704756
143821596	143821619	8	-	26472758	K562	viability	GCAGCAGCTCACCAACCTGCAGG	PUF60	ENSG00000179950	-3.3761676827854306	[491]	[39]	-8	hSpCas9	negative selection	704757
143808603	143808626	CHR_HSCHR8_3_CTG7	-	26472758	K562	viability	GCAGCAGCTCACCAACCTGCAGG	PUF60	ENSG00000274081	-3.3761676827854306	[491]	[39]	-8	hSpCas9	negative selection	704758
143816909	143816932	8	-	26472758	K562	viability	GAAGCTGCTCCGCAAGCAGGAGG	PUF60	ENSG00000179950	-0.5664650058714038	[306]	[174]	-4	hSpCas9	negative selection	704759
143803916	143803939	CHR_HSCHR8_3_CTG7	-	26472758	K562	viability	GAAGCTGCTCCGCAAGCAGGAGG	PUF60	ENSG00000274081	-0.5664650058714038	[306]	[174]	-4	hSpCas9	negative selection	704760
143808867	143808890	CHR_HSCHR8_3_CTG7	-	26472758	K562	viability	AGAGCACAGCCGCCAAGCTGGGG	PUF60	ENSG00000274081	-3.325436880664501	[94]	[7]	-8	hSpCas9	negative selection	704761
143821860	143821883	8	-	26472758	K562	viability	AGAGCACAGCCGCCAAGCTGGGG	PUF60	ENSG00000179950	-3.325436880664501	[94]	[7]	-8	hSpCas9	negative selection	704762
143821829	143821852	8	-	26472758	K562	viability	CCTGACGCCCGAGCAGCAGGAGG	PUF60	ENSG00000179950	-2.5875982486254263	[412]	[57]	-8	hSpCas9	negative selection	704763
143808836	143808859	CHR_HSCHR8_3_CTG7	-	26472758	K562	viability	CCTGACGCCCGAGCAGCAGGAGG	PUF60	ENSG00000274081	-2.5875982486254263	[412]	[57]	-8	hSpCas9	negative selection	704764
143817702	143817725	8	-	26472758	K562	viability	GGGTGGCCAGTACTTGCGGGTGG	PUF60	ENSG00000179950	-5.310170124011191	[140]	[2]	-9	hSpCas9	negative selection	704765
143804709	143804732	CHR_HSCHR8_3_CTG7	-	26472758	K562	viability	GGGTGGCCAGTACTTGCGGGTGG	PUF60	ENSG00000274081	-5.310170124011191	[140]	[2]	-9	hSpCas9	negative selection	704766
143804627	143804650	CHR_HSCHR8_3_CTG7	+	26472758	K562	viability	GCAGCTGCCACAGCAGCGGCAGG	PUF60	ENSG00000274081	0.24441872766644757	[0]	[0]	2	hSpCas9	negative selection	704767
143817620	143817643	8	+	26472758	K562	viability	GCAGCTGCCACAGCAGCGGCAGG	PUF60	ENSG00000179950	0.24441872766644757	[0]	[0]	2	hSpCas9	negative selection	704768
143804092	143804115	CHR_HSCHR8_3_CTG7	+	26472758	K562	viability	GGGTTCACCACTCCCACCGAGGG	PUF60	ENSG00000274081	-1.2454540045349871	[454]	[161]	-6	hSpCas9	negative selection	704769
143817085	143817108	8	+	26472758	K562	viability	GGGTTCACCACTCCCACCGAGGG	PUF60	ENSG00000179950	-1.2454540045349871	[454]	[161]	-6	hSpCas9	negative selection	704770
143821668	143821691	8	-	26472758	K562	viability	TCAGGCCAAGAAGTACGCCATGG	PUF60	ENSG00000179950	-4.662471867942072	[509]	[16]	-9	hSpCas9	negative selection	704771
143808675	143808698	CHR_HSCHR8_3_CTG7	-	26472758	K562	viability	TCAGGCCAAGAAGTACGCCATGG	PUF60	ENSG00000274081	-4.662471867942072	[509]	[16]	-9	hSpCas9	negative selection	704772
143808651	143808674	CHR_HSCHR8_3_CTG7	-	26472758	K562	viability	GCAGAGCATCAAGAGTGTGCTGG	PUF60	ENSG00000274081	-4.277118392913076	[711]	[30]	-9	hSpCas9	negative selection	704773
143821644	143821667	8	-	26472758	K562	viability	GCAGAGCATCAAGAGTGTGCTGG	PUF60	ENSG00000179950	-4.277118392913076	[711]	[30]	-9	hSpCas9	negative selection	704774
143817914	143817937	8	+	26627737	DLD1	viability	GCAGGACTTGATCTTGCCAAAGG	PUF60	ENSG00000179950	0.7711336086766033	[160]	[127,60,69]	7	hSpCas9	negative selection	838549
143818372	143818395	8	-	26627737	DLD1	viability	CTCCGTCACCATGAAGCACAAGG	PUF60	ENSG00000179950	-0.880029140237967	[935]	[209,113,151]	-7	hSpCas9	negative selection	838550
143820664	143820687	8	+	26627737	DLD1	viability	ACCGATTGCAAAGGTGAGAGAGG	PUF60	ENSG00000179950	-1.7849575160559632	[619]	[14,147,15]	-8	hSpCas9	negative selection	838551
143821668	143821691	8	-	26627737	DLD1	viability	TCAGGCCAAGAAGTACGCCATGG	PUF60	ENSG00000179950	-4.470812359819445	[356]	[1,0,10]	-9	hSpCas9	negative selection	838552
143824376	143824399	8	-	26627737	DLD1	viability	AGGTCAATGGCCAGCAAGGAGGG	PUF60	ENSG00000179950	-0.6503404562928706	[624]	[78,133,155]	-6	hSpCas9	negative selection	838553
143829294	143829317	8	-	26627737	DLD1	viability	CGACGGACGCAAGATGGCGACGG	PUF60	ENSG00000179950	-3.181433415970348	[1328]	[2,6,114]	-9	hSpCas9	negative selection	838554
143817914	143817937	8	+	26627737	GBM cells	viability after 5 days	GCAGGACTTGATCTTGCCAAAGG	PUF60	ENSG00000179950	1.947823475366632	[28]	[57,61]	9	hSpCas9	negative selection	920864
143818372	143818395	8	-	26627737	GBM cells	viability after 5 days	CTCCGTCACCATGAAGCACAAGG	PUF60	ENSG00000179950	0.49007619194177177	[386]	[261,320]	7	hSpCas9	negative selection	920865
143820664	143820687	8	+	26627737	GBM cells	viability after 5 days	ACCGATTGCAAAGGTGAGAGAGG	PUF60	ENSG00000179950	0.4441926741343596	[515]	[374,377]	6	hSpCas9	negative selection	920866
143821668	143821691	8	-	26627737	GBM cells	viability after 5 days	TCAGGCCAAGAAGTACGCCATGG	PUF60	ENSG00000179950	-2.4569615519250148	[214]	[27,13]	-9	hSpCas9	negative selection	920867
143824376	143824399	8	-	26627737	GBM cells	viability after 5 days	AGGTCAATGGCCAGCAAGGAGGG	PUF60	ENSG00000179950	0.05049629620619528	[342]	[164,215]	0	hSpCas9	negative selection	920868
143829294	143829317	8	-	26627737	GBM cells	viability after 5 days	CGACGGACGCAAGATGGCGACGG	PUF60	ENSG00000179950	-1.644707830454571	[343]	[84,32]	-9	hSpCas9	negative selection	920869
143817914	143817937	8	+	26627737	GBM cells	viability after 13 days	GCAGGACTTGATCTTGCCAAAGG	PUF60	ENSG00000179950	1.6390484471768714	[28]	[64,35]	9	hSpCas9	negative selection	1003179
143818372	143818395	8	-	26627737	GBM cells	viability after 13 days	CTCCGTCACCATGAAGCACAAGG	PUF60	ENSG00000179950	0.2915379166279153	[386]	[331,195]	4	hSpCas9	negative selection	1003180
143820664	143820687	8	+	26627737	GBM cells	viability after 13 days	ACCGATTGCAAAGGTGAGAGAGG	PUF60	ENSG00000179950	0.8194148798247187	[515]	[621,389]	8	hSpCas9	negative selection	1003181
143821668	143821691	8	-	26627737	GBM cells	viability after 13 days	TCAGGCCAAGAAGTACGCCATGG	PUF60	ENSG00000179950	-1.8611257514810973	[214]	[46,19]	-9	hSpCas9	negative selection	1003182
143824376	143824399	8	-	26627737	GBM cells	viability after 13 days	AGGTCAATGGCCAGCAAGGAGGG	PUF60	ENSG00000179950	-0.35188192775798194	[342]	[136,152]	-4	hSpCas9	negative selection	1003183
143829294	143829317	8	-	26627737	GBM cells	viability after 13 days	CGACGGACGCAAGATGGCGACGG	PUF60	ENSG00000179950	-2.6386861362081766	[343]	[40,20]	-9	hSpCas9	negative selection	1003184
143817914	143817937	8	+	26627737	GBM cells	viability after 21 days	GCAGGACTTGATCTTGCCAAAGG	PUF60	ENSG00000179950	1.7631199161232838	[28]	[53,52]	9	hSpCas9	negative selection	1085494
143818372	143818395	8	-	26627737	GBM cells	viability after 21 days	CTCCGTCACCATGAAGCACAAGG	PUF60	ENSG00000179950	0.4591910766629512	[386]	[287,289]	5	hSpCas9	negative selection	1085495
143820664	143820687	8	+	26627737	GBM cells	viability after 21 days	ACCGATTGCAAAGGTGAGAGAGG	PUF60	ENSG00000179950	0.6398350902248944	[515]	[464,410]	6	hSpCas9	negative selection	1085496
143821668	143821691	8	-	26627737	GBM cells	viability after 21 days	TCAGGCCAAGAAGTACGCCATGG	PUF60	ENSG00000179950	-4.272349805053136	[214]	[4,6]	-9	hSpCas9	negative selection	1085497
143824376	143824399	8	-	26627737	GBM cells	viability after 21 days	AGGTCAATGGCCAGCAAGGAGGG	PUF60	ENSG00000179950	0.0384480412804053	[342]	[205,177]	0	hSpCas9	negative selection	1085498
143829294	143829317	8	-	26627737	GBM cells	viability after 21 days	CGACGGACGCAAGATGGCGACGG	PUF60	ENSG00000179950	-3.4039811420675954	[343]	[13,20]	-9	hSpCas9	negative selection	1085499
143817914	143817937	8	+	26627737	RPE1	viability after 9 days	GCAGGACTTGATCTTGCCAAAGG	PUF60	ENSG00000179950	-0.15134529949877207	[350]	[70,134]	-1	hSpCas9	negative selection	1167809
143818372	143818395	8	-	26627737	RPE1	viability after 9 days	CTCCGTCACCATGAAGCACAAGG	PUF60	ENSG00000179950	-2.2082097466427744	[2612]	[252,78]	-9	hSpCas9	negative selection	1167810
143820664	143820687	8	+	26627737	RPE1	viability after 9 days	ACCGATTGCAAAGGTGAGAGAGG	PUF60	ENSG00000179950	0.7773508839536452	[783]	[390,458]	5	hSpCas9	negative selection	1167811
143821668	143821691	8	-	26627737	RPE1	viability after 9 days	TCAGGCCAAGAAGTACGCCATGG	PUF60	ENSG00000179950	-6.890607507856272	[378]	[0,0]	-9	hSpCas9	negative selection	1167812
143824376	143824399	8	-	26627737	RPE1	viability after 9 days	AGGTCAATGGCCAGCAAGGAGGG	PUF60	ENSG00000179950	0.7618028129010694	[589]	[255,386]	5	hSpCas9	negative selection	1167813
143829294	143829317	8	-	26627737	RPE1	viability after 9 days	CGACGGACGCAAGATGGCGACGG	PUF60	ENSG00000179950	-0.5016079351855978	[309]	[61,76]	-4	hSpCas9	negative selection	1167814
143817914	143817937	8	+	26627737	RPE1	viability after 12 days	GCAGGACTTGATCTTGCCAAAGG	PUF60	ENSG00000179950	-0.7350298633475412	[350]	[78,32]	-5	hSpCas9	negative selection	1250124
143818372	143818395	8	-	26627737	RPE1	viability after 12 days	CTCCGTCACCATGAAGCACAAGG	PUF60	ENSG00000179950	-3.1443128953912876	[2612]	[109,46]	-9	hSpCas9	negative selection	1250125
143820664	143820687	8	+	26627737	RPE1	viability after 12 days	ACCGATTGCAAAGGTGAGAGAGG	PUF60	ENSG00000179950	0.1990720019196907	[783]	[285,194]	1	hSpCas9	negative selection	1250126
143821668	143821691	8	-	26627737	RPE1	viability after 12 days	TCAGGCCAAGAAGTACGCCATGG	PUF60	ENSG00000179950	-6.669942626497955	[378]	[0,0]	-9	hSpCas9	negative selection	1250127
143824376	143824399	8	-	26627737	RPE1	viability after 12 days	AGGTCAATGGCCAGCAAGGAGGG	PUF60	ENSG00000179950	0.5300238782734814	[589]	[241,214]	3	hSpCas9	negative selection	1250128
143829294	143829317	8	-	26627737	RPE1	viability after 12 days	CGACGGACGCAAGATGGCGACGG	PUF60	ENSG00000179950	-0.5327318871307365	[309]	[76,36]	-4	hSpCas9	negative selection	1250129
143817914	143817937	8	+	26627737	RPE1	viability after 15 days	GCAGGACTTGATCTTGCCAAAGG	PUF60	ENSG00000179950	-0.2226138610593762	[350]	[107,62]	-1	hSpCas9	negative selection	1332439
143818372	143818395	8	-	26627737	RPE1	viability after 15 days	CTCCGTCACCATGAAGCACAAGG	PUF60	ENSG00000179950	-2.958993893946671	[2612]	[147,43]	-9	hSpCas9	negative selection	1332440
143820664	143820687	8	+	26627737	RPE1	viability after 15 days	ACCGATTGCAAAGGTGAGAGAGG	PUF60	ENSG00000179950	0.4841738731316249	[783]	[297,321]	3	hSpCas9	negative selection	1332441
143821668	143821691	8	-	26627737	RPE1	viability after 15 days	TCAGGCCAAGAAGTACGCCATGG	PUF60	ENSG00000179950	-6.744305164299197	[378]	[0,0]	-9	hSpCas9	negative selection	1332442
143824376	143824399	8	-	26627737	RPE1	viability after 15 days	AGGTCAATGGCCAGCAAGGAGGG	PUF60	ENSG00000179950	0.9730170999929058	[589]	[461,197]	6	hSpCas9	negative selection	1332443
143829294	143829317	8	-	26627737	RPE1	viability after 15 days	CGACGGACGCAAGATGGCGACGG	PUF60	ENSG00000179950	-0.4787544741041845	[309]	[66,58]	-3	hSpCas9	negative selection	1332444
143817914	143817937	8	+	26627737	RPE1	viability after 18 days	GCAGGACTTGATCTTGCCAAAGG	PUF60	ENSG00000179950	-0.5285349341842782	[350]	[55,75]	-3	hSpCas9	negative selection	1414754
143818372	143818395	8	-	26627737	RPE1	viability after 18 days	CTCCGTCACCATGAAGCACAAGG	PUF60	ENSG00000179950	-3.820978564191222	[2612]	[75,21]	-9	hSpCas9	negative selection	1414755
143820664	143820687	8	+	26627737	RPE1	viability after 18 days	ACCGATTGCAAAGGTGAGAGAGG	PUF60	ENSG00000179950	0.18313045805066921	[783]	[158,326]	1	hSpCas9	negative selection	1414756
143821668	143821691	8	-	26627737	RPE1	viability after 18 days	TCAGGCCAAGAAGTACGCCATGG	PUF60	ENSG00000179950	-6.676385778070349	[378]	[0,0]	-9	hSpCas9	negative selection	1414757
143824376	143824399	8	-	26627737	RPE1	viability after 18 days	AGGTCAATGGCCAGCAAGGAGGG	PUF60	ENSG00000179950	0.6945742033788993	[589]	[233,282]	4	hSpCas9	negative selection	1414758
143829294	143829317	8	-	26627737	RPE1	viability after 18 days	CGACGGACGCAAGATGGCGACGG	PUF60	ENSG00000179950	-1.425877678670988	[309]	[5,57]	-7	hSpCas9	negative selection	1414759
143817914	143817937	8	+	26627737	HeLa	viability after 8 days	GCAGGACTTGATCTTGCCAAAGG	PUF60	ENSG00000179950	-0.27562451008700206	[306]	[209,91,54]	-3	hSpCas9	negative selection	1497069
143818372	143818395	8	-	26627737	HeLa	viability after 8 days	CTCCGTCACCATGAAGCACAAGG	PUF60	ENSG00000179950	1.21929081718821	[308]	[249,431,247]	8	hSpCas9	negative selection	1497070
143820664	143820687	8	+	26627737	HeLa	viability after 8 days	ACCGATTGCAAAGGTGAGAGAGG	PUF60	ENSG00000179950	-0.22089154607846506	[897]	[396,443,188]	-2	hSpCas9	negative selection	1497071
143821668	143821691	8	-	26627737	HeLa	viability after 8 days	TCAGGCCAAGAAGTACGCCATGG	PUF60	ENSG00000179950	-1.8361644890100395	[293]	[38,0,65]	-9	hSpCas9	negative selection	1497072
143824376	143824399	8	-	26627737	HeLa	viability after 8 days	AGGTCAATGGCCAGCAAGGAGGG	PUF60	ENSG00000179950	-0.5728026999147302	[630]	[282,204,93]	-5	hSpCas9	negative selection	1497073
143829294	143829317	8	-	26627737	HeLa	viability after 8 days	CGACGGACGCAAGATGGCGACGG	PUF60	ENSG00000179950	-0.79507671340379	[824]	[197,69,340]	-7	hSpCas9	negative selection	1497074
143817914	143817937	8	+	26627737	HeLa	viability after 12 days	GCAGGACTTGATCTTGCCAAAGG	PUF60	ENSG00000179950	-0.2565320981334084	[306]	[156,40,128]	-2	hSpCas9	negative selection	1579384
143818372	143818395	8	-	26627737	HeLa	viability after 12 days	CTCCGTCACCATGAAGCACAAGG	PUF60	ENSG00000179950	0.6790131402098609	[308]	[144,115,359]	5	hSpCas9	negative selection	1579385
143820664	143820687	8	+	26627737	HeLa	viability after 12 days	ACCGATTGCAAAGGTGAGAGAGG	PUF60	ENSG00000179950	0.06569953912125981	[897]	[306,301,562]	0	hSpCas9	negative selection	1579386
143821668	143821691	8	-	26627737	HeLa	viability after 12 days	TCAGGCCAAGAAGTACGCCATGG	PUF60	ENSG00000179950	-2.298003902709247	[293]	[2,0,71]	-9	hSpCas9	negative selection	1579387
143824376	143824399	8	-	26627737	HeLa	viability after 12 days	AGGTCAATGGCCAGCAAGGAGGG	PUF60	ENSG00000179950	-0.5544801730832024	[630]	[243,154,137]	-5	hSpCas9	negative selection	1579388
143829294	143829317	8	-	26627737	HeLa	viability after 12 days	CGACGGACGCAAGATGGCGACGG	PUF60	ENSG00000179950	-1.114061005033875	[824]	[75,26,380]	-7	hSpCas9	negative selection	1579389
143817914	143817937	8	+	26627737	HeLa	viability after 15 days	GCAGGACTTGATCTTGCCAAAGG	PUF60	ENSG00000179950	-0.23866274463335746	[306]	[113,129,70]	-2	hSpCas9	negative selection	1661699
143818372	143818395	8	-	26627737	HeLa	viability after 15 days	CTCCGTCACCATGAAGCACAAGG	PUF60	ENSG00000179950	1.5400149902766698	[308]	[331,337,432]	8	hSpCas9	negative selection	1661700
143820664	143820687	8	+	26627737	HeLa	viability after 15 days	ACCGATTGCAAAGGTGAGAGAGG	PUF60	ENSG00000179950	-0.5577063286796475	[897]	[213,325,201]	-5	hSpCas9	negative selection	1661701
143821668	143821691	8	-	26627737	HeLa	viability after 15 days	TCAGGCCAAGAAGTACGCCATGG	PUF60	ENSG00000179950	-6.903139232528359	[293]	[0,0,0]	-9	hSpCas9	negative selection	1661702
143824376	143824399	8	-	26627737	HeLa	viability after 15 days	AGGTCAATGGCCAGCAAGGAGGG	PUF60	ENSG00000179950	-0.3454838942972827	[630]	[256,216,125]	-3	hSpCas9	negative selection	1661703
143829294	143829317	8	-	26627737	HeLa	viability after 15 days	CGACGGACGCAAGATGGCGACGG	PUF60	ENSG00000179950	-0.9172528459155174	[824]	[104,51,393]	-7	hSpCas9	negative selection	1661704
143817914	143817937	8	+	26627737	HeLa	viability after 18 days	GCAGGACTTGATCTTGCCAAAGG	PUF60	ENSG00000179950	-0.28277764628684976	[306]	[69,107,70]	-2	hSpCas9	negative selection	1744014
143818372	143818395	8	-	26627737	HeLa	viability after 18 days	CTCCGTCACCATGAAGCACAAGG	PUF60	ENSG00000179950	1.53012866286834	[308]	[220,275,432]	8	hSpCas9	negative selection	1744015
143820664	143820687	8	+	26627737	HeLa	viability after 18 days	ACCGATTGCAAAGGTGAGAGAGG	PUF60	ENSG00000179950	-0.636683695148312	[897]	[128,255,201]	-5	hSpCas9	negative selection	1744016
143821668	143821691	8	-	26627737	HeLa	viability after 18 days	TCAGGCCAAGAAGTACGCCATGG	PUF60	ENSG00000179950	-6.592933580874492	[293]	[0,0,0]	-9	hSpCas9	negative selection	1744017
143824376	143824399	8	-	26627737	HeLa	viability after 18 days	AGGTCAATGGCCAGCAAGGAGGG	PUF60	ENSG00000179950	-0.3042004661063539	[630]	[181,181,125]	-3	hSpCas9	negative selection	1744018
143829294	143829317	8	-	26627737	HeLa	viability after 18 days	CGACGGACGCAAGATGGCGACGG	PUF60	ENSG00000179950	-0.9043715909999067	[824]	[75,39,393]	-7	hSpCas9	negative selection	1744019
143817914	143817937	8	+	26627737	HCT116	viability after 6 days	GCAGGACTTGATCTTGCCAAAGG	PUF60	ENSG00000179950	0.3830737317677018	[556]	[12,169]	2	hSpCas9	negative selection	1826329
143818372	143818395	8	-	26627737	HCT116	viability after 6 days	CTCCGTCACCATGAAGCACAAGG	PUF60	ENSG00000179950	0.06641645249037509	[862]	[308,49]	0	hSpCas9	negative selection	1826330
143820664	143820687	8	+	26627737	HCT116	viability after 6 days	ACCGATTGCAAAGGTGAGAGAGG	PUF60	ENSG00000179950	-0.5064606217439777	[1674]	[127,216]	-3	hSpCas9	negative selection	1826331
143821668	143821691	8	-	26627737	HCT116	viability after 6 days	TCAGGCCAAGAAGTACGCCATGG	PUF60	ENSG00000179950	-5.225588538605061	[660]	[5,0]	-9	hSpCas9	negative selection	1826332
143824376	143824399	8	-	26627737	HCT116	viability after 6 days	AGGTCAATGGCCAGCAAGGAGGG	PUF60	ENSG00000179950	1.9942530755726324	[771]	[935,233]	8	hSpCas9	negative selection	1826333
143829294	143829317	8	-	26627737	HCT116	viability after 6 days	CGACGGACGCAAGATGGCGACGG	PUF60	ENSG00000179950	-1.9956772506641107	[739]	[72,4]	-8	hSpCas9	negative selection	1826334
143817914	143817937	8	+	26627737	HCT116	viability after 8 days	GCAGGACTTGATCTTGCCAAAGG	PUF60	ENSG00000179950	1.2900248881074032	[96]	[144,86,159]	9	hSpCas9	negative selection	1908644
143818372	143818395	8	-	26627737	HCT116	viability after 8 days	CTCCGTCACCATGAAGCACAAGG	PUF60	ENSG00000179950	-0.36850658100411393	[686]	[221,247,406]	-4	hSpCas9	negative selection	1908645
143820664	143820687	8	+	26627737	HCT116	viability after 8 days	ACCGATTGCAAAGGTGAGAGAGG	PUF60	ENSG00000179950	-0.5169640608877296	[684]	[234,223,330]	-6	hSpCas9	negative selection	1908646
143821668	143821691	8	-	26627737	HCT116	viability after 8 days	TCAGGCCAAGAAGTACGCCATGG	PUF60	ENSG00000179950	-4.4825937498450505	[299]	[0,7,12]	-9	hSpCas9	negative selection	1908647
143824376	143824399	8	-	26627737	HCT116	viability after 8 days	AGGTCAATGGCCAGCAAGGAGGG	PUF60	ENSG00000179950	0.16582131014382062	[460]	[279,305,268]	2	hSpCas9	negative selection	1908648
143829294	143829317	8	-	26627737	HCT116	viability after 8 days	CGACGGACGCAAGATGGCGACGG	PUF60	ENSG00000179950	-0.20481390610203004	[347]	[138,139,218]	-2	hSpCas9	negative selection	1908649
143817914	143817937	8	+	26627737	HCT116	viability after 9 days	GCAGGACTTGATCTTGCCAAAGG	PUF60	ENSG00000179950	0.06944160507948408	[556]	[288,50]	0	hSpCas9	negative selection	1990959
143818372	143818395	8	-	26627737	HCT116	viability after 9 days	CTCCGTCACCATGAAGCACAAGG	PUF60	ENSG00000179950	0.8106278298350306	[862]	[411,397]	6	hSpCas9	negative selection	1990960
143820664	143820687	8	+	26627737	HCT116	viability after 9 days	ACCGATTGCAAAGGTGAGAGAGG	PUF60	ENSG00000179950	-0.2772320235373189	[1674]	[191,508]	-2	hSpCas9	negative selection	1990961
143821668	143821691	8	-	26627737	HCT116	viability after 9 days	TCAGGCCAAGAAGTACGCCATGG	PUF60	ENSG00000179950	-3.5030450143408602	[660]	[33,0]	-9	hSpCas9	negative selection	1990962
143824376	143824399	8	-	26627737	HCT116	viability after 9 days	AGGTCAATGGCCAGCAAGGAGGG	PUF60	ENSG00000179950	-0.2257481328821483	[771]	[206,151]	-1	hSpCas9	negative selection	1990963
143829294	143829317	8	-	26627737	HCT116	viability after 9 days	CGACGGACGCAAGATGGCGACGG	PUF60	ENSG00000179950	-0.20777926117347942	[739]	[360,20]	-1	hSpCas9	negative selection	1990964
143817914	143817937	8	+	26627737	HCT116	viability after 12 days	GCAGGACTTGATCTTGCCAAAGG	PUF60	ENSG00000179950	1.0326371993304768	[96]	[109,130,71]	8	hSpCas9	negative selection	2073274
143818372	143818395	8	-	26627737	HCT116	viability after 12 days	CTCCGTCACCATGAAGCACAAGG	PUF60	ENSG00000179950	-0.33472873762187083	[686]	[363,285,201]	-4	hSpCas9	negative selection	2073275
143820664	143820687	8	+	26627737	HCT116	viability after 12 days	ACCGATTGCAAAGGTGAGAGAGG	PUF60	ENSG00000179950	-0.7793679991615351	[684]	[167,214,249]	-7	hSpCas9	negative selection	2073276
143821668	143821691	8	-	26627737	HCT116	viability after 12 days	TCAGGCCAAGAAGTACGCCATGG	PUF60	ENSG00000179950	-5.0752037669737495	[299]	[3,0,8]	-9	hSpCas9	negative selection	2073277
143824376	143824399	8	-	26627737	HCT116	viability after 12 days	AGGTCAATGGCCAGCAAGGAGGG	PUF60	ENSG00000179950	0.07960121108978824	[460]	[211,383,178]	0	hSpCas9	negative selection	2073278
143829294	143829317	8	-	26627737	HCT116	viability after 12 days	CGACGGACGCAAGATGGCGACGG	PUF60	ENSG00000179950	-0.09013205598619109	[347]	[316,102,80]	-1	hSpCas9	negative selection	2073279
143817914	143817937	8	+	26627737	HCT116	viability after 15 days	GCAGGACTTGATCTTGCCAAAGG	PUF60	ENSG00000179950	0.9261098282197515	[96]	[133,82,103]	7	hSpCas9	negative selection	2155589
143818372	143818395	8	-	26627737	HCT116	viability after 15 days	CTCCGTCACCATGAAGCACAAGG	PUF60	ENSG00000179950	-0.8522709510076237	[686]	[414,250,15]	-7	hSpCas9	negative selection	2155590
143820664	143820687	8	+	26627737	HCT116	viability after 15 days	ACCGATTGCAAAGGTGAGAGAGG	PUF60	ENSG00000179950	-0.9470775692978527	[684]	[238,223,153]	-7	hSpCas9	negative selection	2155591
143821668	143821691	8	-	26627737	HCT116	viability after 15 days	TCAGGCCAAGAAGTACGCCATGG	PUF60	ENSG00000179950	-3.0390983324988268	[299]	[0,0,57]	-9	hSpCas9	negative selection	2155592
143824376	143824399	8	-	26627737	HCT116	viability after 15 days	AGGTCAATGGCCAGCAAGGAGGG	PUF60	ENSG00000179950	-0.043775751721704004	[460]	[370,205,207]	0	hSpCas9	negative selection	2155593
143829294	143829317	8	-	26627737	HCT116	viability after 15 days	CGACGGACGCAAGATGGCGACGG	PUF60	ENSG00000179950	-0.25214435021963577	[347]	[325,55,140]	-3	hSpCas9	negative selection	2155594
143817914	143817937	8	+	26627737	HCT116	viability after 18 days	GCAGGACTTGATCTTGCCAAAGG	PUF60	ENSG00000179950	1.283442325801462	[96]	[209,52,81]	8	hSpCas9	negative selection	2237904
143818372	143818395	8	-	26627737	HCT116	viability after 18 days	CTCCGTCACCATGAAGCACAAGG	PUF60	ENSG00000179950	-0.40148892991379703	[686]	[285,342,112]	-4	hSpCas9	negative selection	2237905
143820664	143820687	8	+	26627737	HCT116	viability after 18 days	ACCGATTGCAAAGGTGAGAGAGG	PUF60	ENSG00000179950	-0.43754373143491243	[684]	[258,157,325]	-4	hSpCas9	negative selection	2237906
143821668	143821691	8	-	26627737	HCT116	viability after 18 days	TCAGGCCAAGAAGTACGCCATGG	PUF60	ENSG00000179950	-3.193748761765736	[299]	[0,0,47]	-9	hSpCas9	negative selection	2237907
143824376	143824399	8	-	26627737	HCT116	viability after 18 days	AGGTCAATGGCCAGCAAGGAGGG	PUF60	ENSG00000179950	0.39386908146009425	[460]	[271,416,175]	3	hSpCas9	negative selection	2237908
143829294	143829317	8	-	26627737	HCT116	viability after 18 days	CGACGGACGCAAGATGGCGACGG	PUF60	ENSG00000179950	0.16563948235151849	[347]	[224,114,232]	1	hSpCas9	negative selection	2237909
143821602	143821625	8	+	24336569	HL60	viability	GGTTGGTGAGCTGCTGCTGCTGG	PUF60	ENSG00000179950	-0.9166890788398823	[685]	[768]	-7	hSpCas9	negative selection	2287687
143821612	143821635	8	+	24336569	HL60	viability	CTGCTGCTGCTGGTGCGCGATGG	PUF60	ENSG00000179950	5.525866213120715	[1]	[194]	9	hSpCas9	negative selection	2287688
143821644	143821667	8	-	24336569	HL60	viability	GCAGAGCATCAAGAGTGTGCTGG	PUF60	ENSG00000179950	-1.414990520929518	[561]	[445]	-8	hSpCas9	negative selection	2287689
143821651	143821674	8	+	24336569	HL60	viability	ACTCTTGATGCTCTGCTCCATGG	PUF60	ENSG00000179950	-1.2115880940132335	[428]	[391]	-8	hSpCas9	negative selection	2287690
143821663	143821686	8	+	24336569	HL60	viability	CTGCTCCATGGCGTACTTCTTGG	PUF60	ENSG00000179950	-0.341331227384007	[545]	[911]	-3	hSpCas9	negative selection	2287691
143821668	143821691	8	-	24336569	HL60	viability	TCAGGCCAAGAAGTACGCCATGG	PUF60	ENSG00000179950	-3.1598519993136125	[831]	[196]	-9	hSpCas9	negative selection	2287692
143821805	143821828	8	+	24336569	HL60	viability	GGTCCATGCTCACCTTCTGAAGG	PUF60	ENSG00000179950	-1.7137323161284093	[681]	[439]	-9	hSpCas9	negative selection	2287693
143821817	143821840	8	-	24336569	HL60	viability	GCAGCAGGAGGCCCTTCAGAAGG	PUF60	ENSG00000179950	-0.03526031070142832	[337]	[697]	0	hSpCas9	negative selection	2287694
143821829	143821852	8	-	24336569	HL60	viability	CCTGACGCCCGAGCAGCAGGAGG	PUF60	ENSG00000179950	-1.66128787805108	[1120]	[749]	-9	hSpCas9	negative selection	2287695
143821861	143821884	8	-	24336569	HL60	viability	CAGAGCACAGCCGCCAAGCTGGG	PUF60	ENSG00000179950	-0.8771056021227102	[505]	[582]	-7	hSpCas9	negative selection	2287696
143821602	143821625	8	+	24336569	KBM7	viability	GGTTGGTGAGCTGCTGCTGCTGG	PUF60	ENSG00000179950	-0.673662466209785	[423]	[724]	-5	hSpCas9	negative selection	2354864
143821612	143821635	8	+	24336569	KBM7	viability	CTGCTGCTGCTGGTGCGCGATGG	PUF60	ENSG00000179950	-0.6370569954125958	[64]	[113]	-5	hSpCas9	negative selection	2354865
143821644	143821667	8	-	24336569	KBM7	viability	GCAGAGCATCAAGAGTGTGCTGG	PUF60	ENSG00000179950	-0.5712376642999709	[419]	[770]	-4	hSpCas9	negative selection	2354866
143821651	143821674	8	+	24336569	KBM7	viability	ACTCTTGATGCTCTGCTCCATGG	PUF60	ENSG00000179950	-3.6893369427522615	[349]	[73]	-9	hSpCas9	negative selection	2354867
143821663	143821686	8	+	24336569	KBM7	viability	CTGCTCCATGGCGTACTTCTTGG	PUF60	ENSG00000179950	-0.4129609996793066	[349]	[716]	-3	hSpCas9	negative selection	2354868
143821668	143821691	8	-	24336569	KBM7	viability	TCAGGCCAAGAAGTACGCCATGG	PUF60	ENSG00000179950	-3.8954599525147433	[621]	[113]	-9	hSpCas9	negative selection	2354869
143821805	143821828	8	+	24336569	KBM7	viability	GGTCCATGCTCACCTTCTGAAGG	PUF60	ENSG00000179950	0.4917580215444934	[254]	[977]	4	hSpCas9	negative selection	2354870
143821817	143821840	8	-	24336569	KBM7	viability	GCAGCAGGAGGCCCTTCAGAAGG	PUF60	ENSG00000179950	-4.034686969101595	[672]	[111]	-9	hSpCas9	negative selection	2354871
143821829	143821852	8	-	24336569	KBM7	viability	CCTGACGCCCGAGCAGCAGGAGG	PUF60	ENSG00000179950	-2.2138782846732554	[943]	[554]	-8	hSpCas9	negative selection	2354872
143821861	143821884	8	-	24336569	KBM7	viability	CAGAGCACAGCCGCCAAGCTGGG	PUF60	ENSG00000179950	-0.5844610029692695	[347]	[632]	-5	hSpCas9	negative selection	2354873
143829226	143829249	8	+	25494202	A375	resistance to PLX-4720 (puromycin)	CGACCCGGCCCCGCAAGCCGAGG	PUF60	ENSG00000179950	-0.007388840116451245	[232,467]	[41,114]	0	dCas9-VP64	positive selection	2399889
143829247	143829270	8	+	25494202	A375	resistance to PLX-4720 (puromycin)	GGGCCGCCCGCGCTCATGGGGGG	PUF60	ENSG00000179950	0.3276987168014389	[9,9]	[2,1]	1	dCas9-VP64	positive selection	2399890
143829268	143829291	8	+	25494202	A375	resistance to PLX-4720 (puromycin)	GGGCTCACTTACGAGAGCTATGG	PUF60	ENSG00000179950	2.141560564890696	[161,63]	[100,117]	7	dCas9-VP64	positive selection	2399891
143829511	143829534	8	+	25494202	A375	resistance to PLX-4720 (puromycin)	GCGTCTAGGGGCGTGCGCCGCGG	PUF60	ENSG00000179950	0.5027033135308683	[24,65]	[15,11]	2	dCas9-VP64	positive selection	2443714
143829564	143829587	8	-	25494202	A375	resistance to PLX-4720 (puromycin)	GGTACTACGCACGCCCGCGTCGG	PUF60	ENSG00000179950	1.415736368939713	[333,203]	[226,81]	5	dCas9-VP64	positive selection	2443715
143829541	143829564	8	+	25494202	A375	resistance to PLX-4720 (puromycin)	GTCGGGCGTATCTCTCCGCGTGG	PUF60	ENSG00000179950	2.987421964423922	[8,24]	[24,35]	8	dCas9-VP64	positive selection	2443716
143829226	143829249	8	+	25494202	A375	resistance to PLX-4720 (zeocin)	CGACCCGGCCCCGCAAGCCGAGG	PUF60	ENSG00000179950	1.389013290277171	[75,73]	[50,75]	7	dCas9-VP64	positive selection	2495144
143829247	143829270	8	+	25494202	A375	resistance to PLX-4720 (zeocin)	GGGCCGCCCGCGCTCATGGGGGG	PUF60	ENSG00000179950	-0.6361910302464423	[111,107]	[22,21]	-6	dCas9-VP64	positive selection	2495145
143829268	143829291	8	+	25494202	A375	resistance to PLX-4720 (zeocin)	GGGCTCACTTACGAGAGCTATGG	PUF60	ENSG00000179950	-0.22003974686102667	[392,237]	[112,65]	-2	dCas9-VP64	positive selection	2495146
143829511	143829534	8	+	25494202	A375	resistance to PLX-4720 (zeocin)	GCGTCTAGGGGCGTGCGCCGCGG	PUF60	ENSG00000179950	0.08108009638876282	[32,197]	[23,52]	0	dCas9-VP64	positive selection	2538969
143829564	143829587	8	-	25494202	A375	resistance to PLX-4720 (zeocin)	GGTACTACGCACGCCCGCGTCGG	PUF60	ENSG00000179950	0.993747372181595	[138,123]	[51,115]	6	dCas9-VP64	positive selection	2538970
143829541	143829564	8	+	25494202	A375	resistance to PLX-4720 (zeocin)	GTCGGGCGTATCTCTCCGCGTGG	PUF60	ENSG00000179950	-0.21346512497353848	[68,213]	[25,51]	-2	dCas9-VP64	positive selection	2538971
143818475	143818498	8	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	AGATAGAGCCCACGTAGACGCGG	PUF60	ENSG00000179950	0.5611467750545451	[2,2]	[2,4]	9	hSpCas9	positive selection	3014847
143821596	143821619	8	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCAGCAGCTCACCAACCTGCAGG	PUF60	ENSG00000179950	-0.7476941142227567	[2,2]	[1,0]	-8	hSpCas9	positive selection	3014848
143818460	143818483	8	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCTCTATCTACTATGAGCTGGGG	PUF60	ENSG00000179950	0.5277412367686917	[1,2]	[2,2]	9	hSpCas9	positive selection	3014849
143821668	143821691	8	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TCAGGCCAAGAAGTACGCCATGG	PUF60	ENSG00000179950	0.7485903249112497	[1,0]	[3,1]	9	hSpCas9	positive selection	3014850
143818475	143818498	8	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	AGATAGAGCCCACGTAGACGCGG	PUF60	ENSG00000179950	-0.46297363002300057	[2,2]	[2,0]	-6	hSpCas9	positive selection	3082705
143821596	143821619	8	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCAGCAGCTCACCAACCTGCAGG	PUF60	ENSG00000179950	-0.9718628312401663	[2,2]	[0,0]	-9	hSpCas9	positive selection	3082706
143818460	143818483	8	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCTCTATCTACTATGAGCTGGGG	PUF60	ENSG00000179950	0.7201933593137825	[1,1]	[0,2]	9	hSpCas9	positive selection	3082707
143821668	143821691	8	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TCAGGCCAAGAAGTACGCCATGG	PUF60	ENSG00000179950	-0.8986713165481518	[1,1]	[0,0]	-9	hSpCas9	positive selection	3082708
143818483	143818506		-	24336571	A375	resistance to PLX after 7 days	CATCATGTGCCGCGTCTACGTGG	PUF60	ENSG00000179950	0.08150039531208708	[16,26]	[22,23]	3	hSpCas9	positive selection	3138952
143821881	143821904		+	24336571	A375	resistance to PLX after 7 days	CTGCCCGTTCTCCATCTTGATGG	PUF60	ENSG00000179950	0.0132212385958963	[22,18]	[20,20]	0	hSpCas9	positive selection	3138954
143821862	143821885		-	24336571	A375	resistance to PLX after 7 days	GCAGAGCACAGCCGCCAAGCTGG	PUF60	ENSG00000179950	-0.21071801962253434	[7,5]	[4,5]	-6	hSpCas9	positive selection	3138955
143818397	143818420		-	24336571	A375	resistance to PLX after 7 days	TCAAGAGCATCGACATGTCCTGG	PUF60	ENSG00000179950	0.13513175964184088	[55,60]	[65,60]	4	hSpCas9	positive selection	3138956
143821832	143821855		-	24336571	A375	resistance to PLX after 7 days	TCCCCTGACGCCCGAGCAGCAGG	PUF60	ENSG00000179950	-0.21031304656939964	[28,28]	[23,25]	-6	hSpCas9	positive selection	3138957
143818483	143818506		-	24336571	A375	resistance to PLX after 14 days	CATCATGTGCCGCGTCTACGTGG	PUF60	ENSG00000179950	-0.3135964457048978	[13,17]	[6,4]	-4	hSpCas9	positive selection	3196745
143821881	143821904		+	24336571	A375	resistance to PLX after 14 days	CTGCCCGTTCTCCATCTTGATGG	PUF60	ENSG00000179950	-0.46843392174123377	[18,11]	[3,5]	-5	hSpCas9	positive selection	3196747
143821862	143821885		-	24336571	A375	resistance to PLX after 14 days	GCAGAGCACAGCCGCCAAGCTGG	PUF60	ENSG00000179950	-0.39835004997625933	[7,6]	[1,1]	-5	hSpCas9	positive selection	3196748
143818397	143818420		-	24336571	A375	resistance to PLX after 14 days	TCAAGAGCATCGACATGTCCTGG	PUF60	ENSG00000179950	-0.3138223627175627	[51,49]	[17,19]	-4	hSpCas9	positive selection	3196749
143821832	143821855		-	24336571	A375	resistance to PLX after 14 days	TCCCCTGACGCCCGAGCAGCAGG	PUF60	ENSG00000179950	-0.39263162509752425	[23,23]	[6,8]	-5	hSpCas9	positive selection	3196750
143818483	143818506		-	24336571	A375	viability after 7 days	CATCATGTGCCGCGTCTACGTGG	PUF60	ENSG00000179950	-0.7824112822923632	[40]	[16,26]	-8	hSpCas9	negative selection	3254538
143821881	143821904		+	24336571	A375	viability after 7 days	CTGCCCGTTCTCCATCTTGATGG	PUF60	ENSG00000179950	-0.25552073200301517	[25]	[22,18]	-4	hSpCas9	negative selection	3254540
143821862	143821885		-	24336571	A375	viability after 7 days	GCAGAGCACAGCCGCCAAGCTGG	PUF60	ENSG00000179950	0.06285997713354496	[6]	[7,5]	0	hSpCas9	negative selection	3254541
143818397	143818420		-	24336571	A375	viability after 7 days	TCAAGAGCATCGACATGTCCTGG	PUF60	ENSG00000179950	-0.2026942078526215	[70]	[55,60]	-3	hSpCas9	negative selection	3254542
143821832	143821855		-	24336571	A375	viability after 7 days	TCCCCTGACGCCCGAGCAGCAGG	PUF60	ENSG00000179950	-0.18743286986004604	[34]	[28,28]	-3	hSpCas9	negative selection	3254543
143818483	143818506		-	24336571	A375	viability after 14 days	CATCATGTGCCGCGTCTACGTGG	PUF60	ENSG00000179950	-1.2110632573164475	[40]	[13,17]	-9	hSpCas9	negative selection	3312331
143821881	143821904		+	24336571	A375	viability after 14 days	CTGCCCGTTCTCCATCTTGATGG	PUF60	ENSG00000179950	-0.6740133860267269	[25]	[18,11]	-7	hSpCas9	negative selection	3312333
143821862	143821885		-	24336571	A375	viability after 14 days	GCAGAGCACAGCCGCCAAGCTGG	PUF60	ENSG00000179950	0.2177743079813902	[6]	[7,6]	3	hSpCas9	negative selection	3312334
143818397	143818420		-	24336571	A375	viability after 14 days	TCAAGAGCATCGACATGTCCTGG	PUF60	ENSG00000179950	-0.369364456176533	[70]	[51,49]	-4	hSpCas9	negative selection	3312335
143821832	143821855		-	24336571	A375	viability after 14 days	TCCCCTGACGCCCGAGCAGCAGG	PUF60	ENSG00000179950	-0.4314619102093724	[34]	[23,23]	-5	hSpCas9	negative selection	3312336
143817430	143817453	8	-	27383988	293T	resistance to West Nile virus (flavivirus)	AGCAGCGGTGCTGGGTACCCTGG	PUF60	ENSG00000179950	0.07741712143090065	[144,144]	[0,0]	0	hSpCas9	positive selection	3388374
143821884	143821907	8	-	27383988	293T	resistance to West Nile virus (flavivirus)	ACTCCATCAAGATGGAGAACGGG	PUF60	ENSG00000179950	-0.5692222758450799	[226,226]	[0,0]	-4	hSpCas9	positive selection	3388375
143821861	143821884	8	-	27383988	293T	resistance to West Nile virus (flavivirus)	CAGAGCACAGCCGCCAAGCTGGG	PUF60	ENSG00000179950	0.11777485904704146	[140,140]	[0,0]	0	hSpCas9	positive selection	3388376
143818474	143818497	8	+	26780180	HT29	viability (Avana library 4 designs)	AGATAGAGCCCACGTAGACGCGG	PUF60	ENSG00000179950	6.05157869957604	[]	[]	9	hSpCas9	negative selection	3453097
143821596	143821619	8	-	26780180	HT29	viability (Avana library 4 designs)	GCAGCAGCTCACCAACCTGCAGG	PUF60	ENSG00000179950	3.7462071478692	[]	[]	9	hSpCas9	negative selection	3453098
143818460	143818483	8	-	26780180	HT29	viability (Avana library 4 designs)	GCTCTATCTACTATGAGCTGGGG	PUF60	ENSG00000179950	4.52752162245866	[]	[]	9	hSpCas9	negative selection	3453099
143821668	143821691	8	-	26780180	HT29	viability (Avana library 4 designs)	TCAGGCCAAGAAGTACGCCATGG	PUF60	ENSG00000179950	4.72011384652453	[]	[]	9	hSpCas9	negative selection	3453100
143818474	143818497	8	+	26780180	A375	viability (Avana lentiCRISPRv2)	AGATAGAGCCCACGTAGACGCGG	PUF60	ENSG00000179950	-17.7294607415317	[]	[]	-9	hSpCas9	negative selection	3549792
143821668	143821691	8	-	26780180	A375	viability (Avana lentiCRISPRv2)	TCAGGCCAAGAAGTACGCCATGG	PUF60	ENSG00000179950	-10.0903008870094	[]	[]	-7	hSpCas9	negative selection	3549793
143818460	143818483	8	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCTCTATCTACTATGAGCTGGGG	PUF60	ENSG00000179950	-11.8437860673339	[]	[]	-8	hSpCas9	negative selection	3549794
143821596	143821619	8	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCAGCAGCTCACCAACCTGCAGG	PUF60	ENSG00000179950	-6.24976215852355	[]	[]	-6	hSpCas9	negative selection	3549795
143818410	143818433	8	+	26780180	A375	viability (Avana lentiCRISPRv2)	ATGCTCTTGATGGGGCCAAAGGG	PUF60	ENSG00000179950	4.07219125572211	[]	[]	6	hSpCas9	negative selection	3549796
143821806	143821829	8	+	26780180	A375	viability (Avana lentiCRISPRv2)	GTCCATGCTCACCTTCTGAAGGG	PUF60	ENSG00000179950	-1.24949251218367	[]	[]	-1	hSpCas9	negative selection	3549797
143818474	143818497	8	+	26780180	A375	viability (Avana lentiGuide)	AGATAGAGCCCACGTAGACGCGG	PUF60	ENSG00000179950	27.032603086372	[]	[]	9	hSpCas9	negative selection	3658451
143821668	143821691	8	-	26780180	A375	viability (Avana lentiGuide)	TCAGGCCAAGAAGTACGCCATGG	PUF60	ENSG00000179950	25.5360884300056	[]	[]	9	hSpCas9	negative selection	3658452
143818460	143818483	8	-	26780180	A375	viability (Avana lentiGuide)	GCTCTATCTACTATGAGCTGGGG	PUF60	ENSG00000179950	22.2292888897685	[]	[]	9	hSpCas9	negative selection	3658453
143821596	143821619	8	-	26780180	A375	viability (Avana lentiGuide)	GCAGCAGCTCACCAACCTGCAGG	PUF60	ENSG00000179950	20.8239283250132	[]	[]	8	hSpCas9	negative selection	3658454
143818410	143818433	8	+	26780180	A375	viability (Avana lentiGuide)	ATGCTCTTGATGGGGCCAAAGGG	PUF60	ENSG00000179950	3.60610158119013	[]	[]	3	hSpCas9	negative selection	3658455
143821806	143821829	8	+	26780180	A375	viability (Avana lentiGuide)	GTCCATGCTCACCTTCTGAAGGG	PUF60	ENSG00000179950	19.9333515951129	[]	[]	8	hSpCas9	negative selection	3658456
143818474	143818497	8	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AGATAGAGCCCACGTAGACGCGG	PUF60	ENSG00000179950	-1.5693376747181473	[6]	[1,1]	-9	hSpCas9	positive selection	3767058
143821668	143821691	8	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TCAGGCCAAGAAGTACGCCATGG	PUF60	ENSG00000179950	-1.5436946882108116	[3]	[0,0]	-9	hSpCas9	positive selection	3767059
143818460	143818483	8	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCTCTATCTACTATGAGCTGGGG	PUF60	ENSG00000179950	-0.6613718250991927	[5]	[3,2]	-7	hSpCas9	positive selection	3767060
143821596	143821619	8	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCAGCAGCTCACCAACCTGCAGG	PUF60	ENSG00000179950	-0.20659956651565053	[4]	[3,2]	-3	hSpCas9	positive selection	3767061
143818410	143818433	8	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ATGCTCTTGATGGGGCCAAAGGG	PUF60	ENSG00000179950	0.22805558813831378	[4]	[5,5]	6	hSpCas9	positive selection	3767062
143821806	143821829	8	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GTCCATGCTCACCTTCTGAAGGG	PUF60	ENSG00000179950	-0.09711593609684717	[5]	[4,4]	-2	hSpCas9	positive selection	3767063
143818474	143818497	8	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AGATAGAGCCCACGTAGACGCGG	PUF60	ENSG00000179950	-1.220263699676045	[6]	[0,2]	-9	hSpCas9	positive selection	3875665
143821668	143821691	8	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TCAGGCCAAGAAGTACGCCATGG	PUF60	ENSG00000179950	-2.3115080515823334	[4]	[0,0]	-9	hSpCas9	positive selection	3875666
143818460	143818483	8	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCTCTATCTACTATGAGCTGGGG	PUF60	ENSG00000179950	-2.0350280202244293	[5]	[0,0]	-9	hSpCas9	positive selection	3875667
143821596	143821619	8	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCAGCAGCTCACCAACCTGCAGG	PUF60	ENSG00000179950	-1.013554208831222	[4]	[2,0]	-8	hSpCas9	positive selection	3875668
143818410	143818433	8	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ATGCTCTTGATGGGGCCAAAGGG	PUF60	ENSG00000179950	0.19585992130354535	[5]	[4,4]	5	hSpCas9	positive selection	3875669
143821806	143821829	8	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GTCCATGCTCACCTTCTGAAGGG	PUF60	ENSG00000179950	-1.4535064355494642	[5]	[2,0]	-9	hSpCas9	positive selection	3875670
143821884	143821907	8	-	26780180	A375	viability	ACTCCATCAAGATGGAGAACGGG	PUF60	ENSG00000179950	2.49874257130269	[]	[]	9	hSpCas9	negative selection	3986087
143818474	143818497	8	+	26780180	A375	viability	AGATAGAGCCCACGTAGACGCGG	PUF60	ENSG00000179950	2.17753554060707	[]	[]	9	hSpCas9	negative selection	3986088
143817430	143817453	8	-	26780180	A375	viability	AGCAGCGGTGCTGGGTACCCTGG	PUF60	ENSG00000179950	1.5019233463096	[]	[]	8	hSpCas9	negative selection	3986089
143821861	143821884	8	-	26780180	A375	viability	CAGAGCACAGCCGCCAAGCTGGG	PUF60	ENSG00000179950	2.3875348394133	[]	[]	9	hSpCas9	negative selection	3986090
143818483	143818506	8	-	26780180	A375	viability	CATCATGTGCCGCGTCTACGTGG	PUF60	ENSG00000179950	1.25634775081399	[]	[]	6	hSpCas9	negative selection	3986091
143817434	143817457	8	+	26780180	A375	viability	GGTACCCAGCACCGCTGCTCCGG	PUF60	ENSG00000179950	0.72755732033027	[]	[]	2	hSpCas9	negative selection	3986092
143821884	143821907	8	-	26780180	HT29	viability (GeCKOv2 library)	ACTCCATCAAGATGGAGAACGGG	PUF60	ENSG00000179950	3.20255927896461	[]	[]	9	hSpCas9	negative selection	4094053
143818474	143818497	8	+	26780180	HT29	viability (GeCKOv2 library)	AGATAGAGCCCACGTAGACGCGG	PUF60	ENSG00000179950	3.00761709815426	[]	[]	9	hSpCas9	negative selection	4094054
143817430	143817453	8	-	26780180	HT29	viability (GeCKOv2 library)	AGCAGCGGTGCTGGGTACCCTGG	PUF60	ENSG00000179950	2.16475730782928	[]	[]	9	hSpCas9	negative selection	4094055
143821861	143821884	8	-	26780180	HT29	viability (GeCKOv2 library)	CAGAGCACAGCCGCCAAGCTGGG	PUF60	ENSG00000179950	2.04219759672593	[]	[]	9	hSpCas9	negative selection	4094056
143818483	143818506	8	-	26780180	HT29	viability (GeCKOv2 library)	CATCATGTGCCGCGTCTACGTGG	PUF60	ENSG00000179950	1.983402751118	[]	[]	9	hSpCas9	negative selection	4094057
143817434	143817457	8	+	26780180	HT29	viability (GeCKOv2 library)	GGTACCCAGCACCGCTGCTCCGG	PUF60	ENSG00000179950	1.20945143531015	[]	[]	6	hSpCas9	negative selection	4094058
143818483	143818506	8	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CATCATGTGCCGCGTCTACGTGG	PUF60	ENSG00000179950	-0.2649490284883298	[5]	[2,2]	-6	hSpCas9	positive selection	4164250
143821881	143821904	8	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CTGCCCGTTCTCCATCTTGATGG	PUF60	ENSG00000179950	-0.36786900949696155	[4]	[2,2]	-7	hSpCas9	positive selection	4164252
143821862	143821885	8	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GCAGAGCACAGCCGCCAAGCTGG	PUF60	ENSG00000179950	-0.535602672026485	[2]	[0,0]	-8	hSpCas9	positive selection	4164253
143818397	143818420	8	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TCAAGAGCATCGACATGTCCTGG	PUF60	ENSG00000179950	0.14935658853824318	[6]	[4,4]	4	hSpCas9	positive selection	4164254
143821832	143821855	8	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TCCCCTGACGCCCGAGCAGCAGG	PUF60	ENSG00000179950	0.024654947712200392	[4]	[3,2]	0	hSpCas9	positive selection	4164255
143818483	143818506	8	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CATCATGTGCCGCGTCTACGTGG	PUF60	ENSG00000179950	-0.05207136480045549	[4]	[2,2,1,0]	0	hSpCas9	positive selection	4228272
143821881	143821904	8	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CTGCCCGTTCTCCATCTTGATGG	PUF60	ENSG00000179950	0.7990311553042329	[4]	[4,4,0,3]	5	hSpCas9	positive selection	4228274
143821862	143821885	8	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GCAGAGCACAGCCGCCAAGCTGG	PUF60	ENSG00000179950	0.007210049983604962	[3]	[0,3,2,0]	0	hSpCas9	positive selection	4228275
143818397	143818420	8	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TCAAGAGCATCGACATGTCCTGG	PUF60	ENSG00000179950	0.9485577110316635	[5]	[5,5,5,4]	6	hSpCas9	positive selection	4228276
143821832	143821855	8	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TCCCCTGACGCCCGAGCAGCAGG	PUF60	ENSG00000179950	0.23339705062884353	[3]	[3,3,1,0]	1	hSpCas9	positive selection	4228277
143818483	143818506	8	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CATCATGTGCCGCGTCTACGTGG	PUF60	ENSG00000179950	-0.47951769604302463	[1]	[0,0]	-8	hSpCas9	positive selection	4293209
143818474	143818497	8	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AGATAGAGCCCACGTAGACGCGG	PUF60	ENSG00000179950	-1.3318655358427067	[2]	[0,0]	-9	hSpCas9	positive selection	4293210
143817434	143817457	8	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GGTACCCAGCACCGCTGCTCCGG	PUF60	ENSG00000179950	-0.16394354181972914	[1]	[0,0]	-3	hSpCas9	positive selection	4293211
143817430	143817453	8	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AGCAGCGGTGCTGGGTACCCTGG	PUF60	ENSG00000179950	-0.9149664557846575	[2]	[0,0]	-9	hSpCas9	positive selection	4357467
143821884	143821907	8	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ACTCCATCAAGATGGAGAACGGG	PUF60	ENSG00000179950	-1.2674352382450922	[3]	[0,0]	-9	hSpCas9	positive selection	4357468
143821861	143821884	8	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CAGAGCACAGCCGCCAAGCTGGG	PUF60	ENSG00000179950	-0.20299563895395312	[3]	[3,1]	-4	hSpCas9	positive selection	4357469
143817885	143817907	8	+	27760321	OCIAML3	viability	TTGCCAGTTGTGGGGTCCCGGG	PUF60	ENSG00000179950	-1.2792923654107495	[774,662]	[256,196]	-8	hSpCas9	negative selection	4432085
143818025	143818047	8	+	27760321	OCIAML3	viability	CAACTGGTCTATGATGGGCTGG	PUF60	ENSG00000179950	-0.9753188501805683	[1043,873]	[270,521]	-7	hSpCas9	negative selection	4432086
143818053	143818075	8	-	27760321	OCIAML3	viability	TGGGCAGACCCAGCAACATAGG	PUF60	ENSG00000179950	-2.1498174616044854	[523,360]	[60,97]	-9	hSpCas9	negative selection	4432087
143818257	143818279	8	+	27760321	OCIAML3	viability	GGGACCTCATACTCCACGAAGG	PUF60	ENSG00000179950	-2.5218875939940313	[674,587]	[34,151]	-9	hSpCas9	negative selection	4432088
143818485	143818507	8	+	27760321	OCIAML3	viability	ACGTAGACGCGGCACATGATGG	PUF60	ENSG00000179950	-0.7509411999446444	[500,385]	[247,147]	-6	hSpCas9	negative selection	4432089
143817885	143817907	8	+	27760321	OCIAML2	viability	TTGCCAGTTGTGGGGTCCCGGG	PUF60	ENSG00000179950	-1.8357387720389717	[774,662]	[139,191]	-9	hSpCas9	negative selection	4515548
143818025	143818047	8	+	27760321	OCIAML2	viability	CAACTGGTCTATGATGGGCTGG	PUF60	ENSG00000179950	-1.166418802983881	[1043,873]	[285,420]	-8	hSpCas9	negative selection	4515549
143818053	143818075	8	-	27760321	OCIAML2	viability	TGGGCAGACCCAGCAACATAGG	PUF60	ENSG00000179950	-2.245046387280756	[523,360]	[46,110]	-9	hSpCas9	negative selection	4515550
143818257	143818279	8	+	27760321	OCIAML2	viability	GGGACCTCATACTCCACGAAGG	PUF60	ENSG00000179950	-1.5791532961095065	[674,587]	[170,169]	-8	hSpCas9	negative selection	4515551
143818485	143818507	8	+	27760321	OCIAML2	viability	ACGTAGACGCGGCACATGATGG	PUF60	ENSG00000179950	-2.251698036741684	[500,385]	[85,59]	-9	hSpCas9	negative selection	4515552
143817885	143817907	8	+	27760321	MV411	viability	TTGCCAGTTGTGGGGTCCCGGG	PUF60	ENSG00000179950	-1.4168684140369558	[774,662]	[113,271]	-7	hSpCas9	negative selection	4599011
143818025	143818047	8	+	27760321	MV411	viability	CAACTGGTCTATGATGGGCTGG	PUF60	ENSG00000179950	-1.9007301988940497	[1043,873]	[173,160]	-8	hSpCas9	negative selection	4599012
143818053	143818075	8	-	27760321	MV411	viability	TGGGCAGACCCAGCAACATAGG	PUF60	ENSG00000179950	0.36002722850536667	[523,360]	[297,478]	2	hSpCas9	negative selection	4599013
143818257	143818279	8	+	27760321	MV411	viability	GGGACCTCATACTCCACGAAGG	PUF60	ENSG00000179950	-0.7530787356753592	[674,587]	[93,475]	-5	hSpCas9	negative selection	4599014
143818485	143818507	8	+	27760321	MV411	viability	ACGTAGACGCGGCACATGATGG	PUF60	ENSG00000179950	-1.7363536966339619	[500,385]	[75,103]	-8	hSpCas9	negative selection	4599015
143817885	143817907	8	+	27760321	HL60	viability	TTGCCAGTTGTGGGGTCCCGGG	PUF60	ENSG00000179950	-1.3940821171498738	[774,662]	[231,212]	-8	hSpCas9	negative selection	4682474
143818025	143818047	8	+	27760321	HL60	viability	CAACTGGTCTATGATGGGCTGG	PUF60	ENSG00000179950	-1.4193694722048726	[1043,873]	[298,283]	-8	hSpCas9	negative selection	4682475
143818053	143818075	8	-	27760321	HL60	viability	TGGGCAGACCCAGCAACATAGG	PUF60	ENSG00000179950	-1.7546234437817143	[523,360]	[100,110]	-9	hSpCas9	negative selection	4682476
143818257	143818279	8	+	27760321	HL60	viability	GGGACCTCATACTCCACGAAGG	PUF60	ENSG00000179950	-1.0107824857245937	[674,587]	[218,293]	-7	hSpCas9	negative selection	4682477
143818485	143818507	8	+	27760321	HL60	viability	ACGTAGACGCGGCACATGATGG	PUF60	ENSG00000179950	-3.399671393383142	[500,385]	[19,48]	-9	hSpCas9	negative selection	4682478
143817885	143817907	8	+	27760321	HT1080	viability	TTGCCAGTTGTGGGGTCCCGGG	PUF60	ENSG00000179950	-4.033499703222294	[662,517]	[0,28]	-8	hSpCas9	negative selection	4765937
143818025	143818047	8	+	27760321	HT1080	viability	CAACTGGTCTATGATGGGCTGG	PUF60	ENSG00000179950	-5.870844226800444	[873,681]	[0,9]	-8	hSpCas9	negative selection	4765938
143818053	143818075	8	-	27760321	HT1080	viability	TGGGCAGACCCAGCAACATAGG	PUF60	ENSG00000179950	-6.394355374561223	[360,281]	[1,0]	-9	hSpCas9	negative selection	4765939
143818257	143818279	8	+	27760321	HT1080	viability	GGGACCTCATACTCCACGAAGG	PUF60	ENSG00000179950	-7.70424568530466	[587,458]	[0,0]	-9	hSpCas9	negative selection	4765940
143818485	143818507	8	+	27760321	HT1080	viability	ACGTAGACGCGGCACATGATGG	PUF60	ENSG00000179950	-7.096272455615608	[385,300]	[0,0]	-9	hSpCas9	negative selection	4765941
143817885	143817907	8	+	27760321	HT29	viability after 7 days	TTGCCAGTTGTGGGGTCCCGGG	PUF60	ENSG00000179950	-2.5753486103207317	[662,517]	[201,106,84]	-9	hSpCas9	negative selection	4849400
143818025	143818047	8	+	27760321	HT29	viability after 7 days	CAACTGGTCTATGATGGGCTGG	PUF60	ENSG00000179950	-2.161043377815389	[873,681]	[287,173,217]	-9	hSpCas9	negative selection	4849401
143818053	143818075	8	-	27760321	HT29	viability after 7 days	TGGGCAGACCCAGCAACATAGG	PUF60	ENSG00000179950	-4.043470188164674	[360,281]	[7,47,16]	-9	hSpCas9	negative selection	4849402
143818257	143818279	8	+	27760321	HT29	viability after 7 days	GGGACCTCATACTCCACGAAGG	PUF60	ENSG00000179950	-3.1922920423481136	[587,458]	[158,32,41]	-9	hSpCas9	negative selection	4849403
143818485	143818507	8	+	27760321	HT29	viability after 7 days	ACGTAGACGCGGCACATGATGG	PUF60	ENSG00000179950	-3.8351186651991522	[385,300]	[0,71,15]	-9	hSpCas9	negative selection	4849404
143817885	143817907	8	+	27760321	HT29	viability after 25 days	TTGCCAGTTGTGGGGTCCCGGG	PUF60	ENSG00000179950	-4.847093003838331	[662,517]	[12,16,42]	-9	hSpCas9	negative selection	4932863
143818025	143818047	8	+	27760321	HT29	viability after 25 days	CAACTGGTCTATGATGGGCTGG	PUF60	ENSG00000179950	-5.25490065408183	[873,681]	[62,0,0]	-9	hSpCas9	negative selection	4932864
143818053	143818075	8	-	27760321	HT29	viability after 25 days	TGGGCAGACCCAGCAACATAGG	PUF60	ENSG00000179950	-8.520620182232658	[360,281]	[0,0,0]	-9	hSpCas9	negative selection	4932865
143818257	143818279	8	+	27760321	HT29	viability after 25 days	GGGACCTCATACTCCACGAAGG	PUF60	ENSG00000179950	-8.442796343364964	[587,458]	[2,0,0]	-9	hSpCas9	negative selection	4932866
143818485	143818507	8	+	27760321	HT29	viability after 25 days	ACGTAGACGCGGCACATGATGG	PUF60	ENSG00000179950	-8.615954720462133	[385,300]	[0,0,0]	-9	hSpCas9	negative selection	4932867
143817885	143817907	8	+	27760321	HT29	viability after 22 days	TTGCCAGTTGTGGGGTCCCGGG	PUF60	ENSG00000179950	-6.42285556272931	[662,517]	[5,1,15]	-9	hSpCas9	negative selection	5016326
143818025	143818047	8	+	27760321	HT29	viability after 22 days	CAACTGGTCTATGATGGGCTGG	PUF60	ENSG00000179950	-8.378895687979414	[873,681]	[5,0,0]	-9	hSpCas9	negative selection	5016327
143818053	143818075	8	-	27760321	HT29	viability after 22 days	TGGGCAGACCCAGCAACATAGG	PUF60	ENSG00000179950	-7.128154553783231	[360,281]	[0,5,0]	-9	hSpCas9	negative selection	5016328
143818257	143818279	8	+	27760321	HT29	viability after 22 days	GGGACCTCATACTCCACGAAGG	PUF60	ENSG00000179950	-7.831462321701758	[587,458]	[0,5,0]	-9	hSpCas9	negative selection	5016329
143818485	143818507	8	+	27760321	HT29	viability after 22 days	ACGTAGACGCGGCACATGATGG	PUF60	ENSG00000179950	-8.633273352321392	[385,300]	[0,0,0]	-9	hSpCas9	negative selection	5016330
143817885	143817907	8	+	27760321	HT29	viability after 19 days	TTGCCAGTTGTGGGGTCCCGGG	PUF60	ENSG00000179950	-5.550566502204035	[662,517]	[35,8,0]	-9	hSpCas9	negative selection	5099789
143818025	143818047	8	+	27760321	HT29	viability after 19 days	CAACTGGTCTATGATGGGCTGG	PUF60	ENSG00000179950	-7.398592175161956	[873,681]	[14,0,0]	-9	hSpCas9	negative selection	5099790
143818053	143818075	8	-	27760321	HT29	viability after 19 days	TGGGCAGACCCAGCAACATAGG	PUF60	ENSG00000179950	-5.434961043010966	[360,281]	[0,22,0]	-9	hSpCas9	negative selection	5099791
143818257	143818279	8	+	27760321	HT29	viability after 19 days	GGGACCTCATACTCCACGAAGG	PUF60	ENSG00000179950	-8.538084598279703	[587,458]	[2,0,0]	-9	hSpCas9	negative selection	5099792
143818485	143818507	8	+	27760321	HT29	viability after 19 days	ACGTAGACGCGGCACATGATGG	PUF60	ENSG00000179950	-8.61743329989818	[385,300]	[0,0,0]	-9	hSpCas9	negative selection	5099793
143817885	143817907	8	+	27760321	HT29	viability after 16 days	TTGCCAGTTGTGGGGTCCCGGG	PUF60	ENSG00000179950	-6.055167879533837	[662,517]	[11,9,7]	-9	hSpCas9	negative selection	5183252
143818025	143818047	8	+	27760321	HT29	viability after 16 days	CAACTGGTCTATGATGGGCTGG	PUF60	ENSG00000179950	-5.088319355944565	[873,681]	[31,0,44]	-9	hSpCas9	negative selection	5183253
143818053	143818075	8	-	27760321	HT29	viability after 16 days	TGGGCAGACCCAGCAACATAGG	PUF60	ENSG00000179950	-8.490634309247783	[360,281]	[0,0,0]	-9	hSpCas9	negative selection	5183254
143818257	143818279	8	+	27760321	HT29	viability after 16 days	GGGACCTCATACTCCACGAAGG	PUF60	ENSG00000179950	-5.217353918230107	[587,458]	[16,28,0]	-9	hSpCas9	negative selection	5183255
143818485	143818507	8	+	27760321	HT29	viability after 16 days	ACGTAGACGCGGCACATGATGG	PUF60	ENSG00000179950	-8.585968847477258	[385,300]	[0,0,0]	-9	hSpCas9	negative selection	5183256
143817885	143817907	8	+	27760321	HT29	viability after 13 days	TTGCCAGTTGTGGGGTCCCGGG	PUF60	ENSG00000179950	-4.021830298968103	[662,517]	[27,46,50]	-9	hSpCas9	negative selection	5266715
143818025	143818047	8	+	27760321	HT29	viability after 13 days	CAACTGGTCTATGATGGGCTGG	PUF60	ENSG00000179950	-5.536428480874231	[873,681]	[14,17,24]	-9	hSpCas9	negative selection	5266716
143818053	143818075	8	-	27760321	HT29	viability after 13 days	TGGGCAGACCCAGCAACATAGG	PUF60	ENSG00000179950	-8.542921708691921	[360,281]	[0,0,0]	-9	hSpCas9	negative selection	5266717
143818257	143818279	8	+	27760321	HT29	viability after 13 days	GGGACCTCATACTCCACGAAGG	PUF60	ENSG00000179950	-5.335132126726861	[587,458]	[17,26,0]	-9	hSpCas9	negative selection	5266718
143818485	143818507	8	+	27760321	HT29	viability after 13 days	ACGTAGACGCGGCACATGATGG	PUF60	ENSG00000179950	-8.638256246921395	[385,300]	[0,0,0]	-9	hSpCas9	negative selection	5266719
143817885	143817907	8	+	27760321	HT29	viability after 10 days	TTGCCAGTTGTGGGGTCCCGGG	PUF60	ENSG00000179950	-3.9840302842915207	[662,517]	[41,12,82]	-9	hSpCas9	negative selection	5350178
143818025	143818047	8	+	27760321	HT29	viability after 10 days	CAACTGGTCTATGATGGGCTGG	PUF60	ENSG00000179950	-4.0563535214496795	[873,681]	[72,68,33]	-9	hSpCas9	negative selection	5350179
143818053	143818075	8	-	27760321	HT29	viability after 10 days	TGGGCAGACCCAGCAACATAGG	PUF60	ENSG00000179950	-8.648933015852265	[360,281]	[0,0,0]	-9	hSpCas9	negative selection	5350180
143818257	143818279	8	+	27760321	HT29	viability after 10 days	GGGACCTCATACTCCACGAAGG	PUF60	ENSG00000179950	-5.568444890248022	[587,458]	[27,0,11]	-9	hSpCas9	negative selection	5350181
143818485	143818507	8	+	27760321	HT29	viability after 10 days	ACGTAGACGCGGCACATGATGG	PUF60	ENSG00000179950	-8.328583614976171	[385,300]	[1,0,0]	-9	hSpCas9	negative selection	5350182
143817885	143817907	8	+	27760321	MOLM13	viability	TTGCCAGTTGTGGGGTCCCGGG	PUF60	ENSG00000179950	-0.8750373813772201	[774,662]	[112,311]	-5	hSpCas9	negative selection	5433641
143818025	143818047	8	+	27760321	MOLM13	viability	CAACTGGTCTATGATGGGCTGG	PUF60	ENSG00000179950	-1.7418492777355352	[1043,873]	[145,173]	-7	hSpCas9	negative selection	5433642
143818053	143818075	8	-	27760321	MOLM13	viability	TGGGCAGACCCAGCAACATAGG	PUF60	ENSG00000179950	-3.0337571062833955	[523,360]	[14,42]	-9	hSpCas9	negative selection	5433643
143818257	143818279	8	+	27760321	MOLM13	viability	GGGACCTCATACTCCACGAAGG	PUF60	ENSG00000179950	1.1275974567097224	[674,587]	[283,1195]	7	hSpCas9	negative selection	5433644
143818485	143818507	8	+	27760321	MOLM13	viability	ACGTAGACGCGGCACATGATGG	PUF60	ENSG00000179950	-3.0130843830157223	[500,385]	[6,50]	-9	hSpCas9	negative selection	5433645
143829248	143829271	8	+	27661255	K562	viability	GGCCGCCCGCGCTCATGGGGGGG	PUF60	ENSG00000179950	-2.500804902232435	[337,307]	[56,35]	-9	dCas9-KRAB	negative selection	5505378
143829268	143829291	8	+	27661255	K562	viability	GGGCTCACTTACGAGAGCTATGG	PUF60	ENSG00000179950	-1.591932825262759	[490,637]	[136,158]	-9	dCas9-KRAB	negative selection	5505379
143828845	143828868	8	-	27661255	K562	viability	GGGACGGGACCTGTAGAAAGGGG	PUF60	ENSG00000179950	-0.5340646086549083	[1224,1237]	[763,606]	-7	dCas9-KRAB	negative selection	5505380
143829311	143829334	8	-	27661255	K562	viability	GGCGCGCGCGGAGGCCGCGACGG	PUF60	ENSG00000179950	-1.8488980203479344	[311,229]	[74,47]	-9	dCas9-KRAB	negative selection	5505381
143818483	143818506	8	-	27260156	BXPC3	viability	CATCATGTGCCGCGTCTACGTGG	PUF60	ENSG00000179950	-0.6010746482217826	[165]	[75,116,134,135]	-8	hSpCas9	negative selection	5565669
143818474	143818497	8	+	27260156	BXPC3	viability	AGATAGAGCCCACGTAGACGCGG	PUF60	ENSG00000179950	-1.7360420962914593	[384]	[70,129,85,210]	-9	hSpCas9	negative selection	5565670
143817434	143817457	8	+	27260156	BXPC3	viability	GGTACCCAGCACCGCTGCTCCGG	PUF60	ENSG00000179950	-0.17339738262979187	[69]	[74,77,69,29]	-4	hSpCas9	negative selection	5565671
143817430	143817453	8	-	27260156	BXPC3	viability	AGCAGCGGTGCTGGGTACCCTGG	PUF60	ENSG00000179950	-0.0009502740646614161	[239]	[223,254,277,246]	0	hSpCas9	negative selection	5629927
143821884	143821907	8	-	27260156	BXPC3	viability	ACTCCATCAAGATGGAGAACGGG	PUF60	ENSG00000179950	0.022896074468754912	[591]	[602,611,676,622]	0	hSpCas9	negative selection	5629928
143821861	143821884	8	-	27260156	BXPC3	viability	CAGAGCACAGCCGCCAAGCTGGG	PUF60	ENSG00000179950	-0.3449507130812518	[692]	[521,515,600,658]	-6	hSpCas9	negative selection	5629929
143818483	143818506	8	-	27260156	A673	viability	CATCATGTGCCGCGTCTACGTGG	PUF60	ENSG00000179950	-0.5274647505219319	[165]	[142,160,96,152]	-8	hSpCas9	negative selection	5686920
143818474	143818497	8	+	27260156	A673	viability	AGATAGAGCCCACGTAGACGCGG	PUF60	ENSG00000179950	-1.4795251129484337	[384]	[176,145,182,157]	-9	hSpCas9	negative selection	5686921
143817434	143817457	8	+	27260156	A673	viability	GGTACCCAGCACCGCTGCTCCGG	PUF60	ENSG00000179950	-0.10000921619896808	[69]	[105,47,76,86]	-2	hSpCas9	negative selection	5686922
143817430	143817453	8	-	27260156	A673	viability	AGCAGCGGTGCTGGGTACCCTGG	PUF60	ENSG00000179950	-0.07962712275054695	[239]	[310,235,240,309]	-2	hSpCas9	negative selection	5751178
143821884	143821907	8	-	27260156	A673	viability	ACTCCATCAAGATGGAGAACGGG	PUF60	ENSG00000179950	-0.10557323417651174	[591]	[723,558,632,739]	-3	hSpCas9	negative selection	5751179
143821861	143821884	8	-	27260156	A673	viability	CAGAGCACAGCCGCCAAGCTGGG	PUF60	ENSG00000179950	-0.2250666679099514	[692]	[727,737,724,652]	-5	hSpCas9	negative selection	5751180
143818483	143818506	8	-	27260156	A375	viability	CATCATGTGCCGCGTCTACGTGG	PUF60	ENSG00000179950	-1.1826606436438452	[165]	[34,123,61,120]	-8	hSpCas9	negative selection	5808171
143818474	143818497	8	+	27260156	A375	viability	AGATAGAGCCCACGTAGACGCGG	PUF60	ENSG00000179950	-3.5258784642928562	[384]	[24,37,18,69]	-9	hSpCas9	negative selection	5808172
143817434	143817457	8	+	27260156	A375	viability	GGTACCCAGCACCGCTGCTCCGG	PUF60	ENSG00000179950	-0.9204689604298211	[69]	[45,88,9,34]	-8	hSpCas9	negative selection	5808173
143817430	143817453	8	-	27260156	A375	viability	AGCAGCGGTGCTGGGTACCCTGG	PUF60	ENSG00000179950	-0.18936060128484278	[239]	[151,306,264,263]	-3	hSpCas9	negative selection	5872429
143821884	143821907	8	-	27260156	A375	viability	ACTCCATCAAGATGGAGAACGGG	PUF60	ENSG00000179950	0.01849286755122259	[591]	[648,834,594,733]	0	hSpCas9	negative selection	5872430
143821861	143821884	8	-	27260156	A375	viability	CAGAGCACAGCCGCCAAGCTGGG	PUF60	ENSG00000179950	-1.6647517740179394	[692]	[212,213,376,214]	-9	hSpCas9	negative selection	5872431
143818483	143818506	8	-	27260156	COLO741	viability	CATCATGTGCCGCGTCTACGTGG	PUF60	ENSG00000179950	-0.22458872034758248	[165]	[170,130,236]	-5	hSpCas9	negative selection	5929422
143818474	143818497	8	+	27260156	COLO741	viability	AGATAGAGCCCACGTAGACGCGG	PUF60	ENSG00000179950	-1.3554731044467194	[384]	[231,174,173]	-9	hSpCas9	negative selection	5929423
143817434	143817457	8	+	27260156	COLO741	viability	GGTACCCAGCACCGCTGCTCCGG	PUF60	ENSG00000179950	-0.3024149589967018	[69]	[27,102,81]	-6	hSpCas9	negative selection	5929424
143817430	143817453	8	-	27260156	COLO741	viability	AGCAGCGGTGCTGGGTACCCTGG	PUF60	ENSG00000179950	-0.22462858959515009	[239]	[174,390,216]	-5	hSpCas9	negative selection	5993680
143821884	143821907	8	-	27260156	COLO741	viability	ACTCCATCAAGATGGAGAACGGG	PUF60	ENSG00000179950	0.1761491108912312	[591]	[817,900,840]	4	hSpCas9	negative selection	5993681
143821861	143821884	8	-	27260156	COLO741	viability	CAGAGCACAGCCGCCAAGCTGGG	PUF60	ENSG00000179950	-0.537200292548545	[692]	[614,568,642]	-8	hSpCas9	negative selection	5993682
143818483	143818506	8	-	27260156	CAL120	viability	CATCATGTGCCGCGTCTACGTGG	PUF60	ENSG00000179950	-2.157474136737574	[165]	[32,63,39]	-9	hSpCas9	negative selection	6050673
143818474	143818497	8	+	27260156	CAL120	viability	AGATAGAGCCCACGTAGACGCGG	PUF60	ENSG00000179950	-3.7673509111105044	[384]	[41,53,10]	-9	hSpCas9	negative selection	6050674
143817434	143817457	8	+	27260156	CAL120	viability	GGTACCCAGCACCGCTGCTCCGG	PUF60	ENSG00000179950	-1.8085038228692727	[69]	[40,9,25]	-9	hSpCas9	negative selection	6050675
143817430	143817453	8	-	27260156	CAL120	viability	AGCAGCGGTGCTGGGTACCCTGG	PUF60	ENSG00000179950	-0.25368947359408156	[239]	[411,186,177]	-4	hSpCas9	negative selection	6114931
143821884	143821907	8	-	27260156	CAL120	viability	ACTCCATCAAGATGGAGAACGGG	PUF60	ENSG00000179950	0.006186149880960612	[591]	[708,900,606]	0	hSpCas9	negative selection	6114932
143821861	143821884	8	-	27260156	CAL120	viability	CAGAGCACAGCCGCCAAGCTGGG	PUF60	ENSG00000179950	-1.6404235711338466	[692]	[161,402,247]	-9	hSpCas9	negative selection	6114933
143818483	143818506	8	-	27260156	CADOES1	viability	CATCATGTGCCGCGTCTACGTGG	PUF60	ENSG00000179950	-1.1337449613673307	[165]	[69,64,86,58]	-9	hSpCas9	negative selection	6171924
143818474	143818497	8	+	27260156	CADOES1	viability	AGATAGAGCCCACGTAGACGCGG	PUF60	ENSG00000179950	-1.6644819641932214	[384]	[68,125,91,166]	-9	hSpCas9	negative selection	6171925
143817434	143817457	8	+	27260156	CADOES1	viability	GGTACCCAGCACCGCTGCTCCGG	PUF60	ENSG00000179950	-0.9314517459016329	[69]	[34,46,34,18]	-9	hSpCas9	negative selection	6171926
143817430	143817453	8	-	27260156	CADOES1	viability	AGCAGCGGTGCTGGGTACCCTGG	PUF60	ENSG00000179950	-0.055559121353929264	[239]	[178,284,189,204]	-1	hSpCas9	negative selection	6236182
143821884	143821907	8	-	27260156	CADOES1	viability	ACTCCATCAAGATGGAGAACGGG	PUF60	ENSG00000179950	0.19574846770438703	[591]	[560,877,431,652]	3	hSpCas9	negative selection	6236183
143821861	143821884	8	-	27260156	CADOES1	viability	CAGAGCACAGCCGCCAAGCTGGG	PUF60	ENSG00000179950	-0.5554846143766319	[692]	[433,417,442,459]	-7	hSpCas9	negative selection	6236184
143818483	143818506	8	-	27260156	EWS502	viability	CATCATGTGCCGCGTCTACGTGG	PUF60	ENSG00000179950	-1.03386549655387	[165]	[144,70,79,36]	-9	hSpCas9	negative selection	6293175
143818474	143818497	8	+	27260156	EWS502	viability	AGATAGAGCCCACGTAGACGCGG	PUF60	ENSG00000179950	-2.6001429338240905	[384]	[69,46,60,92]	-9	hSpCas9	negative selection	6293176
143817434	143817457	8	+	27260156	EWS502	viability	GGTACCCAGCACCGCTGCTCCGG	PUF60	ENSG00000179950	0.018038809464591576	[69]	[86,36,76,100]	0	hSpCas9	negative selection	6293177
143817430	143817453	8	-	27260156	EWS502	viability	AGCAGCGGTGCTGGGTACCCTGG	PUF60	ENSG00000179950	0.22832202110969024	[239]	[184,352,356,307]	4	hSpCas9	negative selection	6357433
143821884	143821907	8	-	27260156	EWS502	viability	ACTCCATCAAGATGGAGAACGGG	PUF60	ENSG00000179950	-0.09664009905685303	[591]	[595,472,568,717]	-2	hSpCas9	negative selection	6357434
143821861	143821884	8	-	27260156	EWS502	viability	CAGAGCACAGCCGCCAAGCTGGG	PUF60	ENSG00000179950	-0.5011983381689746	[692]	[342,584,689,471]	-7	hSpCas9	negative selection	6357435
143818483	143818506	8	-	27260156	EW8	viability	CATCATGTGCCGCGTCTACGTGG	PUF60	ENSG00000179950	-0.6332214587599263	[165]	[95,18,63,171]	-8	hSpCas9	negative selection	6414426
143818474	143818497	8	+	27260156	EW8	viability	AGATAGAGCCCACGTAGACGCGG	PUF60	ENSG00000179950	-1.8334144125375544	[384]	[58,154,64,71]	-9	hSpCas9	negative selection	6414427
143817434	143817457	8	+	27260156	EW8	viability	GGTACCCAGCACCGCTGCTCCGG	PUF60	ENSG00000179950	-0.5687365077664404	[69]	[52,48,47,2]	-8	hSpCas9	negative selection	6414428
143817430	143817453	8	-	27260156	EW8	viability	AGCAGCGGTGCTGGGTACCCTGG	PUF60	ENSG00000179950	0.11127397593813892	[239]	[223,293,149,183]	2	hSpCas9	negative selection	6478684
143821884	143821907	8	-	27260156	EW8	viability	ACTCCATCAAGATGGAGAACGGG	PUF60	ENSG00000179950	0.20026711739732583	[591]	[570,573,458,616]	3	hSpCas9	negative selection	6478685
143821861	143821884	8	-	27260156	EW8	viability	CAGAGCACAGCCGCCAAGCTGGG	PUF60	ENSG00000179950	-0.2385768949192238	[692]	[476,524,500,395]	-4	hSpCas9	negative selection	6478686
143818483	143818506	8	-	27260156	CORL105	viability	CATCATGTGCCGCGTCTACGTGG	PUF60	ENSG00000179950	-1.2112655573546145	[165]	[133,46,63,89]	-9	hSpCas9	negative selection	6535677
143818474	143818497	8	+	27260156	CORL105	viability	AGATAGAGCCCACGTAGACGCGG	PUF60	ENSG00000179950	-2.063197941008622	[384]	[150,81,123,78]	-9	hSpCas9	negative selection	6535678
143817434	143817457	8	+	27260156	CORL105	viability	GGTACCCAGCACCGCTGCTCCGG	PUF60	ENSG00000179950	0.27863221384868453	[69]	[116,39,41,190]	5	hSpCas9	negative selection	6535679
143817430	143817453	8	-	27260156	CORL105	viability	AGCAGCGGTGCTGGGTACCCTGG	PUF60	ENSG00000179950	-0.511870084448574	[239]	[137,239,170,231]	-7	hSpCas9	negative selection	6599935
143821884	143821907	8	-	27260156	CORL105	viability	ACTCCATCAAGATGGAGAACGGG	PUF60	ENSG00000179950	-0.030376970809952997	[591]	[641,656,827,609]	0	hSpCas9	negative selection	6599936
143821861	143821884	8	-	27260156	CORL105	viability	CAGAGCACAGCCGCCAAGCTGGG	PUF60	ENSG00000179950	-0.6389400447140459	[692]	[545,346,611,596]	-8	hSpCas9	negative selection	6599937
143818483	143818506	8	-	27260156	HS294T	viability	CATCATGTGCCGCGTCTACGTGG	PUF60	ENSG00000179950	-1.2137225818822244	[165]	[13,7,30,65]	-9	hSpCas9	negative selection	6656928
143818474	143818497	8	+	27260156	HS294T	viability	AGATAGAGCCCACGTAGACGCGG	PUF60	ENSG00000179950	-0.5039465325688459	[384]	[33,219,90,71]	-6	hSpCas9	negative selection	6656929
143817434	143817457	8	+	27260156	HS294T	viability	GGTACCCAGCACCGCTGCTCCGG	PUF60	ENSG00000179950	-0.33759743284509813	[69]	[10,17,24,34]	-5	hSpCas9	negative selection	6656930
143817430	143817453	8	-	27260156	HS294T	viability	AGCAGCGGTGCTGGGTACCCTGG	PUF60	ENSG00000179950	-0.3751102756311404	[239]	[82,44,74,84]	-5	hSpCas9	negative selection	6721186
143821884	143821907	8	-	27260156	HS294T	viability	ACTCCATCAAGATGGAGAACGGG	PUF60	ENSG00000179950	0.029247003370502123	[591]	[199,249,208,285]	0	hSpCas9	negative selection	6721187
143821861	143821884	8	-	27260156	HS294T	viability	CAGAGCACAGCCGCCAAGCTGGG	PUF60	ENSG00000179950	-0.3134899565813041	[692]	[124,214,242,301]	-4	hSpCas9	negative selection	6721188
143818483	143818506	8	-	27260156	HCC44	viability	CATCATGTGCCGCGTCTACGTGG	PUF60	ENSG00000179950	-1.544174062766786	[165]	[78,70,33,67]	-9	hSpCas9	negative selection	6778179
143818474	143818497	8	+	27260156	HCC44	viability	AGATAGAGCCCACGTAGACGCGG	PUF60	ENSG00000179950	-2.835177672724614	[384]	[43,31,37,125]	-9	hSpCas9	negative selection	6778180
143817434	143817457	8	+	27260156	HCC44	viability	GGTACCCAGCACCGCTGCTCCGG	PUF60	ENSG00000179950	-0.44255990198744444	[69]	[63,76,81,12]	-6	hSpCas9	negative selection	6778181
143817430	143817453	8	-	27260156	HCC44	viability	AGCAGCGGTGCTGGGTACCCTGG	PUF60	ENSG00000179950	-0.3865972681494412	[239]	[239,116,255,238]	-6	hSpCas9	negative selection	6842437
143821884	143821907	8	-	27260156	HCC44	viability	ACTCCATCAAGATGGAGAACGGG	PUF60	ENSG00000179950	0.1850079130341501	[591]	[1020,488,877,733]	3	hSpCas9	negative selection	6842438
143821861	143821884	8	-	27260156	HCC44	viability	CAGAGCACAGCCGCCAAGCTGGG	PUF60	ENSG00000179950	-1.0071619711907809	[692]	[481,270,357,462]	-8	hSpCas9	negative selection	6842439
143818483	143818506	8	-	27260156	G402	viability	CATCATGTGCCGCGTCTACGTGG	PUF60	ENSG00000179950	-0.7302228684591157	[165]	[17,108,92,245]	-7	hSpCas9	negative selection	6899430
143818474	143818497	8	+	27260156	G402	viability	AGATAGAGCCCACGTAGACGCGG	PUF60	ENSG00000179950	-2.1043494749002707	[384]	[202,210,16,28]	-9	hSpCas9	negative selection	6899431
143817434	143817457	8	+	27260156	G402	viability	GGTACCCAGCACCGCTGCTCCGG	PUF60	ENSG00000179950	-1.4710057703824648	[69]	[0,38,20,56]	-9	hSpCas9	negative selection	6899432
143817430	143817453	8	-	27260156	G402	viability	AGCAGCGGTGCTGGGTACCCTGG	PUF60	ENSG00000179950	-0.3232077607828068	[239]	[267,229,185,254]	-4	hSpCas9	negative selection	6963688
143821884	143821907	8	-	27260156	G402	viability	ACTCCATCAAGATGGAGAACGGG	PUF60	ENSG00000179950	0.34425778475915136	[591]	[942,1070,782,881]	4	hSpCas9	negative selection	6963689
143821861	143821884	8	-	27260156	G402	viability	CAGAGCACAGCCGCCAAGCTGGG	PUF60	ENSG00000179950	-0.8560755707077823	[692]	[386,432,560,471]	-7	hSpCas9	negative selection	6963690
143818483	143818506	8	-	27260156	L33	viability	CATCATGTGCCGCGTCTACGTGG	PUF60	ENSG00000179950	-0.19233223204207928	[165]	[147,71,44,184]	-4	hSpCas9	negative selection	7020681
143818474	143818497	8	+	27260156	L33	viability	AGATAGAGCCCACGTAGACGCGG	PUF60	ENSG00000179950	-1.11157396043117	[384]	[169,54,125,207]	-9	hSpCas9	negative selection	7020682
143817434	143817457	8	+	27260156	L33	viability	GGTACCCAGCACCGCTGCTCCGG	PUF60	ENSG00000179950	0.21564797770904542	[69]	[78,30,40,104]	5	hSpCas9	negative selection	7020683
143817430	143817453	8	-	27260156	L33	viability	AGCAGCGGTGCTGGGTACCCTGG	PUF60	ENSG00000179950	-0.01627294122973255	[239]	[191,94,125,324]	0	hSpCas9	negative selection	7084939
143821884	143821907	8	-	27260156	L33	viability	ACTCCATCAAGATGGAGAACGGG	PUF60	ENSG00000179950	0.0002748788467122343	[591]	[590,232,337,669]	0	hSpCas9	negative selection	7084940
143821861	143821884	8	-	27260156	L33	viability	CAGAGCACAGCCGCCAAGCTGGG	PUF60	ENSG00000179950	-0.018479463151696796	[692]	[743,245,428,707]	0	hSpCas9	negative selection	7084941
143818483	143818506	8	-	27260156	K562	viability	CATCATGTGCCGCGTCTACGTGG	PUF60	ENSG00000179950	-1.170499315996047	[165]	[41,111,13,90]	-8	hSpCas9	negative selection	7141932
143818474	143818497	8	+	27260156	K562	viability	AGATAGAGCCCACGTAGACGCGG	PUF60	ENSG00000179950	-1.6299000055321473	[384]	[16,79,55,260]	-9	hSpCas9	negative selection	7141933
143817434	143817457	8	+	27260156	K562	viability	GGTACCCAGCACCGCTGCTCCGG	PUF60	ENSG00000179950	0.321653949590992	[69]	[138,46,128,6]	4	hSpCas9	negative selection	7141934
143817430	143817453	8	-	27260156	K562	viability	AGCAGCGGTGCTGGGTACCCTGG	PUF60	ENSG00000179950	0.05919166222954586	[239]	[233,121,394,140]	0	hSpCas9	negative selection	7206190
143821884	143821907	8	-	27260156	K562	viability	ACTCCATCAAGATGGAGAACGGG	PUF60	ENSG00000179950	0.4346239192220739	[591]	[682,812,762,594]	5	hSpCas9	negative selection	7206191
143821861	143821884	8	-	27260156	K562	viability	CAGAGCACAGCCGCCAAGCTGGG	PUF60	ENSG00000179950	0.026314135074739564	[692]	[538,506,475,930]	0	hSpCas9	negative selection	7206192
143818483	143818506	8	-	27260156	HT29	viability	CATCATGTGCCGCGTCTACGTGG	PUF60	ENSG00000179950	-1.586051085587604	[165]	[63,53,63,82]	-9	hSpCas9	negative selection	7263183
143818474	143818497	8	+	27260156	HT29	viability	AGATAGAGCCCACGTAGACGCGG	PUF60	ENSG00000179950	-2.8398238729023895	[384]	[108,45,62,46]	-9	hSpCas9	negative selection	7263184
143817434	143817457	8	+	27260156	HT29	viability	GGTACCCAGCACCGCTGCTCCGG	PUF60	ENSG00000179950	-1.4762086249827155	[69]	[33,49,26,14]	-9	hSpCas9	negative selection	7263185
143817430	143817453	8	-	27260156	HT29	viability	AGCAGCGGTGCTGGGTACCCTGG	PUF60	ENSG00000179950	-0.5591240677578966	[239]	[222,208,239,129]	-7	hSpCas9	negative selection	7327441
143821884	143821907	8	-	27260156	HT29	viability	ACTCCATCAAGATGGAGAACGGG	PUF60	ENSG00000179950	0.021044746623648247	[591]	[929,849,608,571]	0	hSpCas9	negative selection	7327442
143821861	143821884	8	-	27260156	HT29	viability	CAGAGCACAGCCGCCAAGCTGGG	PUF60	ENSG00000179950	-1.3564183261984195	[692]	[408,282,412,223]	-9	hSpCas9	negative selection	7327443
143818483	143818506	8	-	27260156	MHHES1	viability	CATCATGTGCCGCGTCTACGTGG	PUF60	ENSG00000179950	-0.9455398860886985	[165]	[81,217,29,71]	-9	hSpCas9	negative selection	7384434
143818474	143818497	8	+	27260156	MHHES1	viability	AGATAGAGCCCACGTAGACGCGG	PUF60	ENSG00000179950	-2.0802574226481365	[384]	[24,84,193,94]	-9	hSpCas9	negative selection	7384435
143817434	143817457	8	+	27260156	MHHES1	viability	GGTACCCAGCACCGCTGCTCCGG	PUF60	ENSG00000179950	-0.33644268494239205	[69]	[87,40,71,50]	-6	hSpCas9	negative selection	7384436
143817430	143817453	8	-	27260156	MHHES1	viability	AGCAGCGGTGCTGGGTACCCTGG	PUF60	ENSG00000179950	-0.43519641583659663	[239]	[290,166,147,196]	-7	hSpCas9	negative selection	7448692
143821884	143821907	8	-	27260156	MHHES1	viability	ACTCCATCAAGATGGAGAACGGG	PUF60	ENSG00000179950	0.28426131070231775	[591]	[949,685,1064,586]	5	hSpCas9	negative selection	7448693
143821861	143821884	8	-	27260156	MHHES1	viability	CAGAGCACAGCCGCCAAGCTGGG	PUF60	ENSG00000179950	-0.8385872941458632	[692]	[469,455,589,266]	-9	hSpCas9	negative selection	7448694
143818483	143818506	8	-	27260156	MEWO	viability	CATCATGTGCCGCGTCTACGTGG	PUF60	ENSG00000179950	-0.6299196545687051	[165]	[47,81,160]	-8	hSpCas9	negative selection	7505685
143818474	143818497	8	+	27260156	MEWO	viability	AGATAGAGCCCACGTAGACGCGG	PUF60	ENSG00000179950	-2.070832242030748	[384]	[115,94,51]	-9	hSpCas9	negative selection	7505686
143817434	143817457	8	+	27260156	MEWO	viability	GGTACCCAGCACCGCTGCTCCGG	PUF60	ENSG00000179950	-0.36027362308076105	[69]	[91,46,21]	-7	hSpCas9	negative selection	7505687
143817430	143817453	8	-	27260156	MEWO	viability	AGCAGCGGTGCTGGGTACCCTGG	PUF60	ENSG00000179950	-0.12905111459055774	[239]	[180,247,181]	-3	hSpCas9	negative selection	7569943
143821884	143821907	8	-	27260156	MEWO	viability	ACTCCATCAAGATGGAGAACGGG	PUF60	ENSG00000179950	0.10160910849644483	[591]	[807,404,611]	2	hSpCas9	negative selection	7569944
143821861	143821884	8	-	27260156	MEWO	viability	CAGAGCACAGCCGCCAAGCTGGG	PUF60	ENSG00000179950	-0.46391816482345705	[692]	[605,348,481]	-7	hSpCas9	negative selection	7569945
143818483	143818506	8	-	27260156	LNCAPCLONEFGC	viability	CATCATGTGCCGCGTCTACGTGG	PUF60	ENSG00000179950	-0.784986828322138	[165]	[73,68,83,122]	-8	hSpCas9	negative selection	7626936
143818474	143818497	8	+	27260156	LNCAPCLONEFGC	viability	AGATAGAGCCCACGTAGACGCGG	PUF60	ENSG00000179950	-2.077052830640599	[384]	[56,104,71,93]	-9	hSpCas9	negative selection	7626937
143817434	143817457	8	+	27260156	LNCAPCLONEFGC	viability	GGTACCCAGCACCGCTGCTCCGG	PUF60	ENSG00000179950	-0.05281033270599966	[69]	[37,27,93,91]	-1	hSpCas9	negative selection	7626938
143817430	143817453	8	-	27260156	LNCAPCLONEFGC	viability	AGCAGCGGTGCTGGGTACCCTGG	PUF60	ENSG00000179950	-0.3354061711540479	[239]	[154,168,214,156]	-5	hSpCas9	negative selection	7691194
143821884	143821907	8	-	27260156	LNCAPCLONEFGC	viability	ACTCCATCAAGATGGAGAACGGG	PUF60	ENSG00000179950	0.4268480058423375	[591]	[802,576,868,663]	6	hSpCas9	negative selection	7691195
143821861	143821884	8	-	27260156	LNCAPCLONEFGC	viability	CAGAGCACAGCCGCCAAGCTGGG	PUF60	ENSG00000179950	-1.0099935072531807	[692]	[318,339,320,265]	-8	hSpCas9	negative selection	7691196
143818483	143818506	8	-	27260156	PANC0327	viability	CATCATGTGCCGCGTCTACGTGG	PUF60	ENSG00000179950	-0.8390990618567686	[165]	[90,15,114,116]	-8	hSpCas9	negative selection	7748187
143818474	143818497	8	+	27260156	PANC0327	viability	AGATAGAGCCCACGTAGACGCGG	PUF60	ENSG00000179950	-5.193024033827386	[384]	[18,2,6,9]	-9	hSpCas9	negative selection	7748188
143817434	143817457	8	+	27260156	PANC0327	viability	GGTACCCAGCACCGCTGCTCCGG	PUF60	ENSG00000179950	-1.7863308585668318	[69]	[34,13,8,15]	-9	hSpCas9	negative selection	7748189
143817430	143817453	8	-	27260156	PANC0327	viability	AGCAGCGGTGCTGGGTACCCTGG	PUF60	ENSG00000179950	-0.010967666404392062	[239]	[371,74,196,232]	0	hSpCas9	negative selection	7812445
143821884	143821907	8	-	27260156	PANC0327	viability	ACTCCATCAAGATGGAGAACGGG	PUF60	ENSG00000179950	0.5113345021845053	[591]	[1378,578,773,339]	7	hSpCas9	negative selection	7812446
143821861	143821884	8	-	27260156	PANC0327	viability	CAGAGCACAGCCGCCAAGCTGGG	PUF60	ENSG00000179950	-0.4695544338623482	[692]	[475,315,329,674]	-6	hSpCas9	negative selection	7812447
143818483	143818506	8	-	27260156	NCIH2009	viability	CATCATGTGCCGCGTCTACGTGG	PUF60	ENSG00000179950	-1.8304451507004122	[165]	[64,91,37]	-9	hSpCas9	negative selection	7869438
143818474	143818497	8	+	27260156	NCIH2009	viability	AGATAGAGCCCACGTAGACGCGG	PUF60	ENSG00000179950	-3.260132346999037	[384]	[57,94,14]	-9	hSpCas9	negative selection	7869439
143817434	143817457	8	+	27260156	NCIH2009	viability	GGTACCCAGCACCGCTGCTCCGG	PUF60	ENSG00000179950	-0.9054417053989487	[69]	[52,35,67]	-8	hSpCas9	negative selection	7869440
143817430	143817453	8	-	27260156	NCIH2009	viability	AGCAGCGGTGCTGGGTACCCTGG	PUF60	ENSG00000179950	-0.20506555627322132	[239]	[317,319,238]	-3	hSpCas9	negative selection	7933696
143821884	143821907	8	-	27260156	NCIH2009	viability	ACTCCATCAAGATGGAGAACGGG	PUF60	ENSG00000179950	0.01869875176975966	[591]	[922,623,985]	0	hSpCas9	negative selection	7933697
143821861	143821884	8	-	27260156	NCIH2009	viability	CAGAGCACAGCCGCCAAGCTGGG	PUF60	ENSG00000179950	-1.5932326960911412	[692]	[284,378,289]	-9	hSpCas9	negative selection	7933698
143818483	143818506	8	-	27260156	NCIH1373	viability	CATCATGTGCCGCGTCTACGTGG	PUF60	ENSG00000179950	-0.5549542525171933	[165]	[372,22,119,8]	-5	hSpCas9	negative selection	7990689
143818474	143818497	8	+	27260156	NCIH1373	viability	AGATAGAGCCCACGTAGACGCGG	PUF60	ENSG00000179950	-2.8407241203995923	[384]	[98,77,42,5]	-9	hSpCas9	negative selection	7990690
143817434	143817457	8	+	27260156	NCIH1373	viability	GGTACCCAGCACCGCTGCTCCGG	PUF60	ENSG00000179950	-0.1517664855168368	[69]	[13,13,92,42]	-1	hSpCas9	negative selection	7990691
143817430	143817453	8	-	27260156	NCIH1373	viability	AGCAGCGGTGCTGGGTACCCTGG	PUF60	ENSG00000179950	-0.6670286346883807	[239]	[238,102,254,23]	-6	hSpCas9	negative selection	8054947
143821884	143821907	8	-	27260156	NCIH1373	viability	ACTCCATCAAGATGGAGAACGGG	PUF60	ENSG00000179950	0.38598992430629264	[591]	[807,836,967,220]	4	hSpCas9	negative selection	8054948
143821861	143821884	8	-	27260156	NCIH1373	viability	CAGAGCACAGCCGCCAAGCTGGG	PUF60	ENSG00000179950	-1.0651727938038675	[692]	[650,315,311,64]	-8	hSpCas9	negative selection	8054949
143818483	143818506	8	-	27260156	PATU8902	viability	CATCATGTGCCGCGTCTACGTGG	PUF60	ENSG00000179950	-2.524469058079889	[165]	[114,6,24,12]	-9	hSpCas9	negative selection	8111940
143818474	143818497	8	+	27260156	PATU8902	viability	AGATAGAGCCCACGTAGACGCGG	PUF60	ENSG00000179950	-5.615631122493269	[384]	[8,31,1,1]	-9	hSpCas9	negative selection	8111941
143817434	143817457	8	+	27260156	PATU8902	viability	GGTACCCAGCACCGCTGCTCCGG	PUF60	ENSG00000179950	-3.814738494079345	[69]	[3,0,1,23]	-9	hSpCas9	negative selection	8111942
143817430	143817453	8	-	27260156	PATU8902	viability	AGCAGCGGTGCTGGGTACCCTGG	PUF60	ENSG00000179950	-0.3621752716138269	[239]	[106,827,52,86]	-4	hSpCas9	negative selection	8176198
143821884	143821907	8	-	27260156	PATU8902	viability	ACTCCATCAAGATGGAGAACGGG	PUF60	ENSG00000179950	0.4303625266697868	[591]	[1368,1548,396,1329]	4	hSpCas9	negative selection	8176199
143821861	143821884	8	-	27260156	PATU8902	viability	CAGAGCACAGCCGCCAAGCTGGG	PUF60	ENSG00000179950	-2.055715269136877	[692]	[336,110,286,167]	-9	hSpCas9	negative selection	8176200
143818483	143818506	8	-	27260156	PANC1	viability	CATCATGTGCCGCGTCTACGTGG	PUF60	ENSG00000179950	-2.1436345734957887	[165]	[10,60,37,25]	-9	hSpCas9	negative selection	8233191
143818474	143818497	8	+	27260156	PANC1	viability	AGATAGAGCCCACGTAGACGCGG	PUF60	ENSG00000179950	-3.7292325498114027	[384]	[13,11,5,58]	-9	hSpCas9	negative selection	8233192
143817434	143817457	8	+	27260156	PANC1	viability	GGTACCCAGCACCGCTGCTCCGG	PUF60	ENSG00000179950	-0.9420707397174617	[69]	[38,28,24,30]	-8	hSpCas9	negative selection	8233193
143817430	143817453	8	-	27260156	PANC1	viability	AGCAGCGGTGCTGGGTACCCTGG	PUF60	ENSG00000179950	-0.5373186840608233	[239]	[127,104,118,196]	-7	hSpCas9	negative selection	8297449
143821884	143821907	8	-	27260156	PANC1	viability	ACTCCATCAAGATGGAGAACGGG	PUF60	ENSG00000179950	0.0006674850862143922	[591]	[457,823,448,381]	0	hSpCas9	negative selection	8297450
143821861	143821884	8	-	27260156	PANC1	viability	CAGAGCACAGCCGCCAAGCTGGG	PUF60	ENSG00000179950	-0.8742280612304869	[692]	[384,281,244,363]	-8	hSpCas9	negative selection	8297451
143818483	143818506	8	-	27260156	PANC0813	viability	CATCATGTGCCGCGTCTACGTGG	PUF60	ENSG00000179950	-1.3520478044493447	[165]	[41,127,53,77]	-9	hSpCas9	negative selection	8354442
143818474	143818497	8	+	27260156	PANC0813	viability	AGATAGAGCCCACGTAGACGCGG	PUF60	ENSG00000179950	-2.2815923745133304	[384]	[96,93,66,112]	-9	hSpCas9	negative selection	8354443
143817434	143817457	8	+	27260156	PANC0813	viability	GGTACCCAGCACCGCTGCTCCGG	PUF60	ENSG00000179950	-1.2062336608582291	[69]	[24,42,11,59]	-9	hSpCas9	negative selection	8354444
143817430	143817453	8	-	27260156	PANC0813	viability	AGCAGCGGTGCTGGGTACCCTGG	PUF60	ENSG00000179950	-0.07870540922187219	[239]	[260,222,297,283]	-1	hSpCas9	negative selection	8418700
143821884	143821907	8	-	27260156	PANC0813	viability	ACTCCATCAAGATGGAGAACGGG	PUF60	ENSG00000179950	-0.17728879658017987	[591]	[614,680,452,703]	-3	hSpCas9	negative selection	8418701
143821861	143821884	8	-	27260156	PANC0813	viability	CAGAGCACAGCCGCCAAGCTGGG	PUF60	ENSG00000179950	-0.9445599853474156	[692]	[307,482,437,449]	-8	hSpCas9	negative selection	8418702
143818483	143818506	8	-	27260156	RDES	viability	CATCATGTGCCGCGTCTACGTGG	PUF60	ENSG00000179950	-1.3141180994970787	[165]	[56,56,113,85]	-9	hSpCas9	negative selection	8475693
143818474	143818497	8	+	27260156	RDES	viability	AGATAGAGCCCACGTAGACGCGG	PUF60	ENSG00000179950	-2.6732494405651477	[384]	[68,30,73,111]	-9	hSpCas9	negative selection	8475694
143817434	143817457	8	+	27260156	RDES	viability	GGTACCCAGCACCGCTGCTCCGG	PUF60	ENSG00000179950	-0.6575626757891779	[69]	[20,90,12,83]	-8	hSpCas9	negative selection	8475695
143817430	143817453	8	-	27260156	RDES	viability	AGCAGCGGTGCTGGGTACCCTGG	PUF60	ENSG00000179950	0.26172621031664656	[239]	[262,396,259,410]	4	hSpCas9	negative selection	8539951
143821884	143821907	8	-	27260156	RDES	viability	ACTCCATCAAGATGGAGAACGGG	PUF60	ENSG00000179950	0.1570568795780063	[591]	[651,777,750,868]	2	hSpCas9	negative selection	8539952
143821861	143821884	8	-	27260156	RDES	viability	CAGAGCACAGCCGCCAAGCTGGG	PUF60	ENSG00000179950	-0.65571590094446	[692]	[389,515,594,539]	-8	hSpCas9	negative selection	8539953
143818483	143818506	8	-	27260156	PC3	viability	CATCATGTGCCGCGTCTACGTGG	PUF60	ENSG00000179950	0.02118576392515159	[165]	[188,73,318,114]	0	hSpCas9	negative selection	8596944
143818474	143818497	8	+	27260156	PC3	viability	AGATAGAGCCCACGTAGACGCGG	PUF60	ENSG00000179950	-1.4662069485620732	[384]	[89,184,143,142]	-9	hSpCas9	negative selection	8596945
143817434	143817457	8	+	27260156	PC3	viability	GGTACCCAGCACCGCTGCTCCGG	PUF60	ENSG00000179950	0.1371095540674956	[69]	[43,125,69,67]	3	hSpCas9	negative selection	8596946
143817430	143817453	8	-	27260156	PC3	viability	AGCAGCGGTGCTGGGTACCCTGG	PUF60	ENSG00000179950	-0.11414313177574886	[239]	[168,87,346,339]	-3	hSpCas9	negative selection	8661202
143821884	143821907	8	-	27260156	PC3	viability	ACTCCATCAAGATGGAGAACGGG	PUF60	ENSG00000179950	0.11353472104037154	[591]	[425,380,1217,805]	2	hSpCas9	negative selection	8661203
143821861	143821884	8	-	27260156	PC3	viability	CAGAGCACAGCCGCCAAGCTGGG	PUF60	ENSG00000179950	-0.01460881044362905	[692]	[350,754,1083,790]	0	hSpCas9	negative selection	8661204
143818483	143818506	8	-	27260156	PATU8988T	viability	CATCATGTGCCGCGTCTACGTGG	PUF60	ENSG00000179950	-1.4833207336835335	[165]	[15,15,149,40]	-9	hSpCas9	negative selection	8718195
143818474	143818497	8	+	27260156	PATU8988T	viability	AGATAGAGCCCACGTAGACGCGG	PUF60	ENSG00000179950	-2.1541902073152137	[384]	[50,84,133,61]	-9	hSpCas9	negative selection	8718196
143817434	143817457	8	+	27260156	PATU8988T	viability	GGTACCCAGCACCGCTGCTCCGG	PUF60	ENSG00000179950	-1.1279668927546425	[69]	[1,14,21,87]	-9	hSpCas9	negative selection	8718197
143817430	143817453	8	-	27260156	PATU8988T	viability	AGCAGCGGTGCTGGGTACCCTGG	PUF60	ENSG00000179950	0.2982402479430015	[239]	[250,433,233,231]	5	hSpCas9	negative selection	8782453
143821884	143821907	8	-	27260156	PATU8988T	viability	ACTCCATCAAGATGGAGAACGGG	PUF60	ENSG00000179950	-0.08042699010475796	[591]	[327,681,644,518]	-1	hSpCas9	negative selection	8782454
143821861	143821884	8	-	27260156	PATU8988T	viability	CAGAGCACAGCCGCCAAGCTGGG	PUF60	ENSG00000179950	-0.7708580771164399	[692]	[334,445,387,406]	-8	hSpCas9	negative selection	8782455
143818483	143818506	8	-	27260156	T47D	viability	CATCATGTGCCGCGTCTACGTGG	PUF60	ENSG00000179950	-0.5746909973886853	[165]	[143,122,104,148]	-8	hSpCas9	negative selection	8839446
143818474	143818497	8	+	27260156	T47D	viability	AGATAGAGCCCACGTAGACGCGG	PUF60	ENSG00000179950	-1.4995783144256059	[384]	[149,141,152,191]	-9	hSpCas9	negative selection	8839447
143817434	143817457	8	+	27260156	T47D	viability	GGTACCCAGCACCGCTGCTCCGG	PUF60	ENSG00000179950	-0.8351046493504701	[69]	[66,54,26,32]	-9	hSpCas9	negative selection	8839448
143817430	143817453	8	-	27260156	T47D	viability	AGCAGCGGTGCTGGGTACCCTGG	PUF60	ENSG00000179950	-0.1439615561123211	[239]	[295,261,247,203]	-3	hSpCas9	negative selection	8903704
143821884	143821907	8	-	27260156	T47D	viability	ACTCCATCAAGATGGAGAACGGG	PUF60	ENSG00000179950	0.17769840614869392	[591]	[792,710,721,904]	4	hSpCas9	negative selection	8903705
143821861	143821884	8	-	27260156	T47D	viability	CAGAGCACAGCCGCCAAGCTGGG	PUF60	ENSG00000179950	-0.6666607444686118	[692]	[570,496,504,460]	-8	hSpCas9	negative selection	8903706
143818483	143818506	8	-	27260156	SU8686	viability	CATCATGTGCCGCGTCTACGTGG	PUF60	ENSG00000179950	-3.207063809112922	[165]	[27,6,14,21]	-9	hSpCas9	negative selection	8960697
143818474	143818497	8	+	27260156	SU8686	viability	AGATAGAGCCCACGTAGACGCGG	PUF60	ENSG00000179950	-2.931875111943305	[384]	[16,19,37,147]	-9	hSpCas9	negative selection	8960698
143817434	143817457	8	+	27260156	SU8686	viability	GGTACCCAGCACCGCTGCTCCGG	PUF60	ENSG00000179950	-0.4908030368284968	[69]	[74,75,13,19]	-7	hSpCas9	negative selection	8960699
143817430	143817453	8	-	27260156	SU8686	viability	AGCAGCGGTGCTGGGTACCCTGG	PUF60	ENSG00000179950	-0.5776281414241762	[239]	[165,159,127,184]	-7	hSpCas9	negative selection	9024955
143821884	143821907	8	-	27260156	SU8686	viability	ACTCCATCAAGATGGAGAACGGG	PUF60	ENSG00000179950	0.0873950863295977	[591]	[429,565,703,859]	1	hSpCas9	negative selection	9024956
143821861	143821884	8	-	27260156	SU8686	viability	CAGAGCACAGCCGCCAAGCTGGG	PUF60	ENSG00000179950	-1.210367494026273	[692]	[299,203,324,382]	-9	hSpCas9	negative selection	9024957
143818483	143818506	8	-	27260156	SKES1	viability	CATCATGTGCCGCGTCTACGTGG	PUF60	ENSG00000179950	-0.49908865190805196	[165]	[155,122,87,107]	-8	hSpCas9	negative selection	9081948
143818474	143818497	8	+	27260156	SKES1	viability	AGATAGAGCCCACGTAGACGCGG	PUF60	ENSG00000179950	-1.2450947683034816	[384]	[186,232,92,147]	-9	hSpCas9	negative selection	9081949
143817434	143817457	8	+	27260156	SKES1	viability	GGTACCCAGCACCGCTGCTCCGG	PUF60	ENSG00000179950	0.13200753419002131	[69]	[82,130,59,42]	3	hSpCas9	negative selection	9081950
143817430	143817453	8	-	27260156	SKES1	viability	AGCAGCGGTGCTGGGTACCCTGG	PUF60	ENSG00000179950	0.3745881644015704	[239]	[202,430,292,310]	7	hSpCas9	negative selection	9146206
143821884	143821907	8	-	27260156	SKES1	viability	ACTCCATCAAGATGGAGAACGGG	PUF60	ENSG00000179950	0.10113294147886204	[591]	[589,572,689,656]	2	hSpCas9	negative selection	9146207
143821861	143821884	8	-	27260156	SKES1	viability	CAGAGCACAGCCGCCAAGCTGGG	PUF60	ENSG00000179950	-0.42871111367653725	[692]	[546,512,377,605]	-7	hSpCas9	negative selection	9146208
143818483	143818506	8	-	27260156	TOV112D	viability	CATCATGTGCCGCGTCTACGTGG	PUF60	ENSG00000179950	-0.051233503264544344	[165]	[68,196,112,260]	-1	hSpCas9	negative selection	9203199
143818474	143818497	8	+	27260156	TOV112D	viability	AGATAGAGCCCACGTAGACGCGG	PUF60	ENSG00000179950	-1.120461566761958	[384]	[121,186,153,241]	-9	hSpCas9	negative selection	9203200
143817434	143817457	8	+	27260156	TOV112D	viability	GGTACCCAGCACCGCTGCTCCGG	PUF60	ENSG00000179950	0.00741334145833239	[69]	[89,132,48,27]	0	hSpCas9	negative selection	9203201
143817430	143817453	8	-	27260156	TOV112D	viability	AGCAGCGGTGCTGGGTACCCTGG	PUF60	ENSG00000179950	-0.05740694922296097	[239]	[274,186,169,282]	-1	hSpCas9	negative selection	9267457
143821884	143821907	8	-	27260156	TOV112D	viability	ACTCCATCAAGATGGAGAACGGG	PUF60	ENSG00000179950	0.18954706556246137	[591]	[654,736,911,419]	3	hSpCas9	negative selection	9267458
143821861	143821884	8	-	27260156	TOV112D	viability	CAGAGCACAGCCGCCAAGCTGGG	PUF60	ENSG00000179950	-0.3976350271534511	[692]	[470,651,565,445]	-7	hSpCas9	negative selection	9267459
143818483	143818506	8	-	27260156	TC71	viability	CATCATGTGCCGCGTCTACGTGG	PUF60	ENSG00000179950	0.004148479274979522	[165]	[202,143,196,167]	0	hSpCas9	negative selection	9324450
143818474	143818497	8	+	27260156	TC71	viability	AGATAGAGCCCACGTAGACGCGG	PUF60	ENSG00000179950	-1.1240314593792418	[384]	[160,171,169,259]	-9	hSpCas9	negative selection	9324451
143817434	143817457	8	+	27260156	TC71	viability	GGTACCCAGCACCGCTGCTCCGG	PUF60	ENSG00000179950	-0.20801723906955027	[69]	[35,63,39,124]	-5	hSpCas9	negative selection	9324452
143817430	143817453	8	-	27260156	TC71	viability	AGCAGCGGTGCTGGGTACCCTGG	PUF60	ENSG00000179950	0.1150046242282321	[239]	[285,272,269,285]	3	hSpCas9	negative selection	9388708
143821884	143821907	8	-	27260156	TC71	viability	ACTCCATCAAGATGGAGAACGGG	PUF60	ENSG00000179950	0.026283479090031314	[591]	[488,720,557,834]	0	hSpCas9	negative selection	9388709
143821861	143821884	8	-	27260156	TC71	viability	CAGAGCACAGCCGCCAAGCTGGG	PUF60	ENSG00000179950	-0.3448774537722855	[692]	[587,586,486,686]	-7	hSpCas9	negative selection	9388710
143818483	143818506	8	-	27260156	TC32	viability	CATCATGTGCCGCGTCTACGTGG	PUF60	ENSG00000179950	-0.5187239784464936	[165]	[117,91,147,80]	-7	hSpCas9	negative selection	9445701
143818474	143818497	8	+	27260156	TC32	viability	AGATAGAGCCCACGTAGACGCGG	PUF60	ENSG00000179950	-1.2770643225581968	[384]	[113,157,191,130]	-9	hSpCas9	negative selection	9445702
143817434	143817457	8	+	27260156	TC32	viability	GGTACCCAGCACCGCTGCTCCGG	PUF60	ENSG00000179950	-0.40983721243230287	[69]	[20,64,41,63]	-6	hSpCas9	negative selection	9445703
143817430	143817453	8	-	27260156	TC32	viability	AGCAGCGGTGCTGGGTACCCTGG	PUF60	ENSG00000179950	0.17886206586079367	[239]	[245,194,299,298]	3	hSpCas9	negative selection	9509959
143821884	143821907	8	-	27260156	TC32	viability	ACTCCATCAAGATGGAGAACGGG	PUF60	ENSG00000179950	0.22869701970127243	[591]	[576,443,945,747]	4	hSpCas9	negative selection	9509960
143821861	143821884	8	-	27260156	TC32	viability	CAGAGCACAGCCGCCAAGCTGGG	PUF60	ENSG00000179950	-0.34678912613109253	[692]	[517,340,662,590]	-6	hSpCas9	negative selection	9509961
143817914	143817937	8	+	27869803	HPAFII	viability after 27 days	GCAGGACTTGATCTTGCCAAAGG	PUF60	ENSG00000179950	0.10589875081899747	[160]	[101,81,NaN]	0	hSpCas9	negative selection	9601653
143818372	143818395	8	-	27869803	HPAFII	viability after 27 days	CTCCGTCACCATGAAGCACAAGG	PUF60	ENSG00000179950	-0.31940154617272437	[363]	[208,106,NaN]	-2	hSpCas9	negative selection	9601654
143820664	143820687	8	+	27869803	HPAFII	viability after 27 days	ACCGATTGCAAAGGTGAGAGAGG	PUF60	ENSG00000179950	0.32612983086597824	[427]	[58,467,NaN]	2	hSpCas9	negative selection	9601655
143821668	143821691	8	-	27869803	HPAFII	viability after 27 days	TCAGGCCAAGAAGTACGCCATGG	PUF60	ENSG00000179950	-6.66838999720936	[298]	[0,1,NaN]	-9	hSpCas9	negative selection	9601656
143824376	143824399	8	-	27869803	HPAFII	viability after 27 days	AGGTCAATGGCCAGCAAGGAGGG	PUF60	ENSG00000179950	0.3393759409623953	[242]	[123,192,NaN]	2	hSpCas9	negative selection	9601657
143829294	143829317	8	-	27869803	HPAFII	viability after 27 days	CGACGGACGCAAGATGGCGACGG	PUF60	ENSG00000179950	-2.036219555085296	[482]	[122,10,NaN]	-8	hSpCas9	negative selection	9601658
143817914	143817937	8	+	27869803	HPAFII	viability after 15 days	GCAGGACTTGATCTTGCCAAAGG	PUF60	ENSG00000179950	-0.1221845585123934	[160]	[129,176,NaN]	-1	hSpCas9	negative selection	9684102
143818372	143818395	8	-	27869803	HPAFII	viability after 15 days	CTCCGTCACCATGAAGCACAAGG	PUF60	ENSG00000179950	-0.025937127933782	[363]	[538,287,NaN]	0	hSpCas9	negative selection	9684103
143820664	143820687	8	+	27869803	HPAFII	viability after 15 days	ACCGATTGCAAAGGTGAGAGAGG	PUF60	ENSG00000179950	-0.02876852565668886	[427]	[305,540,NaN]	0	hSpCas9	negative selection	9684104
143821668	143821691	8	-	27869803	HPAFII	viability after 15 days	TCAGGCCAAGAAGTACGCCATGG	PUF60	ENSG00000179950	-5.944668559650202	[298]	[11,0,NaN]	-9	hSpCas9	negative selection	9684105
143824376	143824399	8	-	27869803	HPAFII	viability after 15 days	AGGTCAATGGCCAGCAAGGAGGG	PUF60	ENSG00000179950	0.5364801629352393	[242]	[482,313,NaN]	6	hSpCas9	negative selection	9684106
143829294	143829317	8	-	27869803	HPAFII	viability after 15 days	CGACGGACGCAAGATGGCGACGG	PUF60	ENSG00000179950	-1.3023709955204306	[482]	[437,68,NaN]	-8	hSpCas9	negative selection	9684107
143817914	143817937	8	+	27869803	ASPC1	viability after 36 days	GCAGGACTTGATCTTGCCAAAGG	PUF60	ENSG00000179950	0.004220880333884125	[274]	[83,177,38]	0	hSpCas9	negative selection	9766551
143818372	143818395	8	-	27869803	ASPC1	viability after 36 days	CTCCGTCACCATGAAGCACAAGG	PUF60	ENSG00000179950	-0.9414748684869154	[750]	[168,156,95]	-7	hSpCas9	negative selection	9766552
143820664	143820687	8	+	27869803	ASPC1	viability after 36 days	ACCGATTGCAAAGGTGAGAGAGG	PUF60	ENSG00000179950	-0.45983174651555475	[1041]	[276,320,207]	-5	hSpCas9	negative selection	9766553
143821668	143821691	8	-	27869803	ASPC1	viability after 36 days	TCAGGCCAAGAAGTACGCCATGG	PUF60	ENSG00000179950	-2.6744793738661996	[562]	[0,0,74]	-9	hSpCas9	negative selection	9766554
143824376	143824399	8	-	27869803	ASPC1	viability after 36 days	AGGTCAATGGCCAGCAAGGAGGG	PUF60	ENSG00000179950	0.22265289396213955	[830]	[588,407,103]	2	hSpCas9	negative selection	9766555
143829294	143829317	8	-	27869803	ASPC1	viability after 36 days	CGACGGACGCAAGATGGCGACGG	PUF60	ENSG00000179950	-0.8310860847658424	[876]	[299,139,105]	-7	hSpCas9	negative selection	9766556
143817914	143817937	8	+	27869803	PATU8988S	viability after 35 days	GCAGGACTTGATCTTGCCAAAGG	PUF60	ENSG00000179950	-0.20481996911876443	[314]	[142,76,NaN]	-2	hSpCas9	negative selection	9849000
143818372	143818395	8	-	27869803	PATU8988S	viability after 35 days	CTCCGTCACCATGAAGCACAAGG	PUF60	ENSG00000179950	-0.4865003785905591	[669]	[236,147,NaN]	-5	hSpCas9	negative selection	9849001
143820664	143820687	8	+	27869803	PATU8988S	viability after 35 days	ACCGATTGCAAAGGTGAGAGAGG	PUF60	ENSG00000179950	-0.1304871027988047	[853]	[184,443,NaN]	-1	hSpCas9	negative selection	9849002
143821668	143821691	8	-	27869803	PATU8988S	viability after 35 days	TCAGGCCAAGAAGTACGCCATGG	PUF60	ENSG00000179950	-3.689467946026418	[591]	[9,26,NaN]	-9	hSpCas9	negative selection	9849003
143824376	143824399	8	-	27869803	PATU8988S	viability after 35 days	AGGTCAATGGCCAGCAAGGAGGG	PUF60	ENSG00000179950	0.23130581144343565	[568]	[275,261,NaN]	2	hSpCas9	negative selection	9849004
143829294	143829317	8	-	27869803	PATU8988S	viability after 35 days	CGACGGACGCAAGATGGCGACGG	PUF60	ENSG00000179950	-0.8547122033887642	[669]	[243,53,NaN]	-7	hSpCas9	negative selection	9849005
143817914	143817937	8	+	27869803	PATU8988S	viability after 31 days	GCAGGACTTGATCTTGCCAAAGG	PUF60	ENSG00000179950	-0.24364807654235832	[314]	[135,67,NaN]	-3	hSpCas9	negative selection	9931449
143818372	143818395	8	-	27869803	PATU8988S	viability after 31 days	CTCCGTCACCATGAAGCACAAGG	PUF60	ENSG00000179950	0.05443426134477769	[669]	[232,333,NaN]	0	hSpCas9	negative selection	9931450
143820664	143820687	8	+	27869803	PATU8988S	viability after 31 days	ACCGATTGCAAAGGTGAGAGAGG	PUF60	ENSG00000179950	0.1346044585165359	[853]	[313,449,NaN]	1	hSpCas9	negative selection	9931451
143821668	143821691	8	-	27869803	PATU8988S	viability after 31 days	TCAGGCCAAGAAGTACGCCATGG	PUF60	ENSG00000179950	-2.830091634674044	[591]	[8,63,NaN]	-9	hSpCas9	negative selection	9931452
143824376	143824399	8	-	27869803	PATU8988S	viability after 31 days	AGGTCAATGGCCAGCAAGGAGGG	PUF60	ENSG00000179950	0.13298820732318287	[568]	[217,287,NaN]	1	hSpCas9	negative selection	9931453
143829294	143829317	8	-	27869803	PATU8988S	viability after 31 days	CGACGGACGCAAGATGGCGACGG	PUF60	ENSG00000179950	-0.6162771248454901	[669]	[179,166,NaN]	-6	hSpCas9	negative selection	9931454
143817914	143817937	8	+	27869803	HPAFII	viability after 35 days	GCAGGACTTGATCTTGCCAAAGG	PUF60	ENSG00000179950	-1.7155028028353865	[160]	[13,36,NaN]	-7	hSpCas9	negative selection	10013898
143818372	143818395	8	-	27869803	HPAFII	viability after 35 days	CTCCGTCACCATGAAGCACAAGG	PUF60	ENSG00000179950	-2.186771567008969	[363]	[47,31,NaN]	-8	hSpCas9	negative selection	10013899
143820664	143820687	8	+	27869803	HPAFII	viability after 35 days	ACCGATTGCAAAGGTGAGAGAGG	PUF60	ENSG00000179950	0.5771766374782964	[427]	[17,666,NaN]	4	hSpCas9	negative selection	10013900
143821668	143821691	8	-	27869803	HPAFII	viability after 35 days	TCAGGCCAAGAAGTACGCCATGG	PUF60	ENSG00000179950	-7.2419131212014305	[298]	[0,0,NaN]	-9	hSpCas9	negative selection	10013901
143824376	143824399	8	-	27869803	HPAFII	viability after 35 days	AGGTCAATGGCCAGCAAGGAGGG	PUF60	ENSG00000179950	0.38599531780989993	[242]	[140,182,NaN]	2	hSpCas9	negative selection	10013902
143829294	143829317	8	-	27869803	HPAFII	viability after 35 days	CGACGGACGCAAGATGGCGACGG	PUF60	ENSG00000179950	-2.1003006889365476	[482]	[104,2,NaN]	-8	hSpCas9	negative selection	10013903
143817914	143817937	8	+	27869803	HPAFII	viability after 31 days	GCAGGACTTGATCTTGCCAAAGG	PUF60	ENSG00000179950	-0.7380854464860669	[160]	[57,49,NaN]	-5	hSpCas9	negative selection	10096347
143818372	143818395	8	-	27869803	HPAFII	viability after 31 days	CTCCGTCACCATGAAGCACAAGG	PUF60	ENSG00000179950	-1.552371992809548	[363]	[72,65,NaN]	-7	hSpCas9	negative selection	10096348
143820664	143820687	8	+	27869803	HPAFII	viability after 31 days	ACCGATTGCAAAGGTGAGAGAGG	PUF60	ENSG00000179950	0.1734447151099905	[427]	[44,516,NaN]	1	hSpCas9	negative selection	10096349
143821668	143821691	8	-	27869803	HPAFII	viability after 31 days	TCAGGCCAAGAAGTACGCCATGG	PUF60	ENSG00000179950	-7.3906304745228475	[298]	[0,0,NaN]	-9	hSpCas9	negative selection	10096350
143824376	143824399	8	-	27869803	HPAFII	viability after 31 days	AGGTCAATGGCCAGCAAGGAGGG	PUF60	ENSG00000179950	0.6633984892747609	[242]	[159,276,NaN]	5	hSpCas9	negative selection	10096351
143829294	143829317	8	-	27869803	HPAFII	viability after 31 days	CGACGGACGCAAGATGGCGACGG	PUF60	ENSG00000179950	-2.424092652134158	[482]	[72,25,NaN]	-8	hSpCas9	negative selection	10096352
143818256	143818279	8	+	28162770	P31FUJ	viability	GGGGACCTCATACTCCACGAAGG	PUF60	ENSG00000179950	-2.4551946257508264	[27]	[5]	-8	hSpCas9	negative selection	10220177
143821596	143821619	8	-	28162770	P31FUJ	viability	GCAGCAGCTCACCAACCTGCAGG	PUF60	ENSG00000179950	-2.647839703693222	[367]	[68]	-9	hSpCas9	negative selection	10220178
143816909	143816932	8	-	28162770	P31FUJ	viability	GAAGCTGCTCCGCAAGCAGGAGG	PUF60	ENSG00000179950	-2.766234404495453	[109]	[18]	-9	hSpCas9	negative selection	10220179
143821860	143821883	8	-	28162770	P31FUJ	viability	AGAGCACAGCCGCCAAGCTGGGG	PUF60	ENSG00000179950	-4.6922338230516765	[21]	[0]	-9	hSpCas9	negative selection	10220180
143821829	143821852	8	-	28162770	P31FUJ	viability	CCTGACGCCCGAGCAGCAGGAGG	PUF60	ENSG00000179950	-3.090783199541951	[144]	[19]	-9	hSpCas9	negative selection	10220181
143817702	143817725	8	-	28162770	P31FUJ	viability	GGGTGGCCAGTACTTGCGGGTGG	PUF60	ENSG00000179950	-5.724655300744053	[44]	[0]	-9	hSpCas9	negative selection	10220182
143817620	143817643	8	+	28162770	P31FUJ	viability	GCAGCTGCCACAGCAGCGGCAGG	PUF60	ENSG00000179950	3.67408839119414	[1]	[29]	9	hSpCas9	negative selection	10220183
143817085	143817108	8	+	28162770	P31FUJ	viability	GGGTTCACCACTCCCACCGAGGG	PUF60	ENSG00000179950	-1.143387283580639	[390]	[207]	-7	hSpCas9	negative selection	10220184
143821668	143821691	8	-	28162770	P31FUJ	viability	TCAGGCCAAGAAGTACGCCATGG	PUF60	ENSG00000179950	-5.132806414437658	[417]	[13]	-9	hSpCas9	negative selection	10220185
143821644	143821667	8	-	28162770	P31FUJ	viability	GCAGAGCATCAAGAGTGTGCTGG	PUF60	ENSG00000179950	-3.7697431902725915	[324]	[27]	-9	hSpCas9	negative selection	10220186
143818256	143818279	8	+	28162770	TF1	viability	GGGGACCTCATACTCCACGAAGG	PUF60	ENSG00000179950	NaN	[NaN]	[0]	1	hSpCas9	negative selection	10389543
143821596	143821619	8	-	28162770	TF1	viability	GCAGCAGCTCACCAACCTGCAGG	PUF60	ENSG00000179950	NaN	[NaN]	[84]	1	hSpCas9	negative selection	10389544
143816909	143816932	8	-	28162770	TF1	viability	GAAGCTGCTCCGCAAGCAGGAGG	PUF60	ENSG00000179950	NaN	[NaN]	[13]	1	hSpCas9	negative selection	10389545
143821860	143821883	8	-	28162770	TF1	viability	AGAGCACAGCCGCCAAGCTGGGG	PUF60	ENSG00000179950	NaN	[NaN]	[1]	1	hSpCas9	negative selection	10389546
143821829	143821852	8	-	28162770	TF1	viability	CCTGACGCCCGAGCAGCAGGAGG	PUF60	ENSG00000179950	NaN	[NaN]	[1]	1	hSpCas9	negative selection	10389547
143817702	143817725	8	-	28162770	TF1	viability	GGGTGGCCAGTACTTGCGGGTGG	PUF60	ENSG00000179950	NaN	[NaN]	[0]	1	hSpCas9	negative selection	10389548
143817620	143817643	8	+	28162770	TF1	viability	GCAGCTGCCACAGCAGCGGCAGG	PUF60	ENSG00000179950	NaN	[NaN]	[5]	1	hSpCas9	negative selection	10389549
143817085	143817108	8	+	28162770	TF1	viability	GGGTTCACCACTCCCACCGAGGG	PUF60	ENSG00000179950	NaN	[NaN]	[203]	1	hSpCas9	negative selection	10389550
143821668	143821691	8	-	28162770	TF1	viability	TCAGGCCAAGAAGTACGCCATGG	PUF60	ENSG00000179950	NaN	[NaN]	[37]	1	hSpCas9	negative selection	10389551
143821644	143821667	8	-	28162770	TF1	viability	GCAGAGCATCAAGAGTGTGCTGG	PUF60	ENSG00000179950	NaN	[NaN]	[75]	1	hSpCas9	negative selection	10389552
143818256	143818279	8	+	28162770	SKM1	viability	GGGGACCTCATACTCCACGAAGG	PUF60	ENSG00000179950	-5.069929211465591	[18]	[0]	-9	hSpCas9	negative selection	10558909
143821596	143821619	8	-	28162770	SKM1	viability	GCAGCAGCTCACCAACCTGCAGG	PUF60	ENSG00000179950	-1.2300864366590822	[68]	[51]	-7	hSpCas9	negative selection	10558910
143816909	143816932	8	-	28162770	SKM1	viability	GAAGCTGCTCCGCAAGCAGGAGG	PUF60	ENSG00000179950	-1.9512847149669716	[34]	[15]	-8	hSpCas9	negative selection	10558911
143821860	143821883	8	-	28162770	SKM1	viability	AGAGCACAGCCGCCAAGCTGGGG	PUF60	ENSG00000179950	-3.2814333166593026	[10]	[1]	-9	hSpCas9	negative selection	10558912
143821829	143821852	8	-	28162770	SKM1	viability	CCTGACGCCCGAGCAGCAGGAGG	PUF60	ENSG00000179950	-0.9767242928206475	[58]	[52]	-6	hSpCas9	negative selection	10558913
143817702	143817725	8	-	28162770	SKM1	viability	GGGTGGCCAGTACTTGCGGGTGG	PUF60	ENSG00000179950	0.07108309806148272	[6]	[12]	0	hSpCas9	negative selection	10558914
143817620	143817643	8	+	28162770	SKM1	viability	GCAGCTGCCACAGCAGCGGCAGG	PUF60	ENSG00000179950	-0.8220016980220048	[0]	[0]	-6	hSpCas9	negative selection	10558915
143817085	143817108	8	+	28162770	SKM1	viability	GGGTTCACCACTCCCACCGAGGG	PUF60	ENSG00000179950	-1.2124611745801834	[96]	[73]	-7	hSpCas9	negative selection	10558916
143821668	143821691	8	-	28162770	SKM1	viability	TCAGGCCAAGAAGTACGCCATGG	PUF60	ENSG00000179950	-5.0850361038558	[95]	[4]	-9	hSpCas9	negative selection	10558917
143821644	143821667	8	-	28162770	SKM1	viability	GCAGAGCATCAAGAGTGTGCTGG	PUF60	ENSG00000179950	-0.8040797900247431	[79]	[80]	-6	hSpCas9	negative selection	10558918
143818256	143818279	8	+	28162770	SKM1	viability	GGGGACCTCATACTCCACGAAGG	PUF60	ENSG00000179950	-5.069929211465591	[18]	[0]	-9	hSpCas9	negative selection	10728275
143821596	143821619	8	-	28162770	SKM1	viability	GCAGCAGCTCACCAACCTGCAGG	PUF60	ENSG00000179950	-1.2300864366590822	[68]	[51]	-7	hSpCas9	negative selection	10728276
143816909	143816932	8	-	28162770	SKM1	viability	GAAGCTGCTCCGCAAGCAGGAGG	PUF60	ENSG00000179950	-1.9512847149669716	[34]	[15]	-8	hSpCas9	negative selection	10728277
143821860	143821883	8	-	28162770	SKM1	viability	AGAGCACAGCCGCCAAGCTGGGG	PUF60	ENSG00000179950	-3.2814333166593026	[10]	[1]	-9	hSpCas9	negative selection	10728278
143821829	143821852	8	-	28162770	SKM1	viability	CCTGACGCCCGAGCAGCAGGAGG	PUF60	ENSG00000179950	-0.9767242928206475	[58]	[52]	-6	hSpCas9	negative selection	10728279
143817702	143817725	8	-	28162770	SKM1	viability	GGGTGGCCAGTACTTGCGGGTGG	PUF60	ENSG00000179950	0.07108309806148272	[6]	[12]	0	hSpCas9	negative selection	10728280
143817620	143817643	8	+	28162770	SKM1	viability	GCAGCTGCCACAGCAGCGGCAGG	PUF60	ENSG00000179950	-0.8220016980220048	[0]	[0]	-6	hSpCas9	negative selection	10728281
143817085	143817108	8	+	28162770	SKM1	viability	GGGTTCACCACTCCCACCGAGGG	PUF60	ENSG00000179950	-1.2124611745801834	[96]	[73]	-7	hSpCas9	negative selection	10728282
143821668	143821691	8	-	28162770	SKM1	viability	TCAGGCCAAGAAGTACGCCATGG	PUF60	ENSG00000179950	-5.0850361038558	[95]	[4]	-9	hSpCas9	negative selection	10728283
143821644	143821667	8	-	28162770	SKM1	viability	GCAGAGCATCAAGAGTGTGCTGG	PUF60	ENSG00000179950	-0.8040797900247431	[79]	[80]	-6	hSpCas9	negative selection	10728284
143818256	143818279	8	+	28162770	PL21	viability	GGGGACCTCATACTCCACGAAGG	PUF60	ENSG00000179950	-0.4145702296258882	[48]	[15]	-3	hSpCas9	negative selection	10897641
143821596	143821619	8	-	28162770	PL21	viability	GCAGCAGCTCACCAACCTGCAGG	PUF60	ENSG00000179950	-0.2988927074446599	[276]	[97]	-2	hSpCas9	negative selection	10897642
143816909	143816932	8	-	28162770	PL21	viability	GAAGCTGCTCCGCAAGCAGGAGG	PUF60	ENSG00000179950	-6.226125140212778	[171]	[0]	-9	hSpCas9	negative selection	10897643
143821860	143821883	8	-	28162770	PL21	viability	AGAGCACAGCCGCCAAGCTGGGG	PUF60	ENSG00000179950	-1.5003001036517727	[25]	[3]	-7	hSpCas9	negative selection	10897644
143821829	143821852	8	-	28162770	PL21	viability	CCTGACGCCCGAGCAGCAGGAGG	PUF60	ENSG00000179950	-3.4682388944194735	[177]	[6]	-9	hSpCas9	negative selection	10897645
143817702	143817725	8	-	28162770	PL21	viability	GGGTGGCCAGTACTTGCGGGTGG	PUF60	ENSG00000179950	-2.5440214810810904	[66]	[4]	-9	hSpCas9	negative selection	10897646
143817620	143817643	8	+	28162770	PL21	viability	GCAGCTGCCACAGCAGCGGCAGG	PUF60	ENSG00000179950	0.20013961448931994	[1]	[0]	1	hSpCas9	negative selection	10897647
143817085	143817108	8	+	28162770	PL21	viability	GGGTTCACCACTCCCACCGAGGG	PUF60	ENSG00000179950	-0.8088491687379346	[321]	[79]	-5	hSpCas9	negative selection	10897648
143821668	143821691	8	-	28162770	PL21	viability	TCAGGCCAAGAAGTACGCCATGG	PUF60	ENSG00000179950	-3.074341317995582	[328]	[16]	-9	hSpCas9	negative selection	10897649
143821644	143821667	8	-	28162770	PL21	viability	GCAGAGCATCAAGAGTGTGCTGG	PUF60	ENSG00000179950	-0.5864567474014867	[275]	[79]	-4	hSpCas9	negative selection	10897650
143818256	143818279	8	+	28162770	P31FUJ	viability	GGGGACCTCATACTCCACGAAGG	PUF60	ENSG00000179950	-2.4551946257508264	[27]	[5]	-8	hSpCas9	negative selection	11067007
143821596	143821619	8	-	28162770	P31FUJ	viability	GCAGCAGCTCACCAACCTGCAGG	PUF60	ENSG00000179950	-2.647839703693222	[367]	[68]	-9	hSpCas9	negative selection	11067008
143816909	143816932	8	-	28162770	P31FUJ	viability	GAAGCTGCTCCGCAAGCAGGAGG	PUF60	ENSG00000179950	-2.766234404495453	[109]	[18]	-9	hSpCas9	negative selection	11067009
143821860	143821883	8	-	28162770	P31FUJ	viability	AGAGCACAGCCGCCAAGCTGGGG	PUF60	ENSG00000179950	-4.6922338230516765	[21]	[0]	-9	hSpCas9	negative selection	11067010
143821829	143821852	8	-	28162770	P31FUJ	viability	CCTGACGCCCGAGCAGCAGGAGG	PUF60	ENSG00000179950	-3.090783199541951	[144]	[19]	-9	hSpCas9	negative selection	11067011
143817702	143817725	8	-	28162770	P31FUJ	viability	GGGTGGCCAGTACTTGCGGGTGG	PUF60	ENSG00000179950	-5.724655300744053	[44]	[0]	-9	hSpCas9	negative selection	11067012
143817620	143817643	8	+	28162770	P31FUJ	viability	GCAGCTGCCACAGCAGCGGCAGG	PUF60	ENSG00000179950	3.67408839119414	[1]	[29]	9	hSpCas9	negative selection	11067013
143817085	143817108	8	+	28162770	P31FUJ	viability	GGGTTCACCACTCCCACCGAGGG	PUF60	ENSG00000179950	-1.143387283580639	[390]	[207]	-7	hSpCas9	negative selection	11067014
143821668	143821691	8	-	28162770	P31FUJ	viability	TCAGGCCAAGAAGTACGCCATGG	PUF60	ENSG00000179950	-5.132806414437658	[417]	[13]	-9	hSpCas9	negative selection	11067015
143821644	143821667	8	-	28162770	P31FUJ	viability	GCAGAGCATCAAGAGTGTGCTGG	PUF60	ENSG00000179950	-3.7697431902725915	[324]	[27]	-9	hSpCas9	negative selection	11067016
143818256	143818279	8	+	28162770	OCIAML5	viability	GGGGACCTCATACTCCACGAAGG	PUF60	ENSG00000179950	-4.659421492921601	[13]	[0]	-9	hSpCas9	negative selection	11236373
143821596	143821619	8	-	28162770	OCIAML5	viability	GCAGCAGCTCACCAACCTGCAGG	PUF60	ENSG00000179950	-1.2805999126270637	[178]	[132]	-6	hSpCas9	negative selection	11236374
143816909	143816932	8	-	28162770	OCIAML5	viability	GAAGCTGCTCCGCAAGCAGGAGG	PUF60	ENSG00000179950	-2.521917969171666	[69]	[21]	-8	hSpCas9	negative selection	11236375
143821860	143821883	8	-	28162770	OCIAML5	viability	AGAGCACAGCCGCCAAGCTGGGG	PUF60	ENSG00000179950	-1.682141569421685	[15]	[8]	-7	hSpCas9	negative selection	11236376
143821829	143821852	8	-	28162770	OCIAML5	viability	CCTGACGCCCGAGCAGCAGGAGG	PUF60	ENSG00000179950	-2.3639656093954295	[76]	[26]	-8	hSpCas9	negative selection	11236377
143817702	143817725	8	-	28162770	OCIAML5	viability	GGGTGGCCAGTACTTGCGGGTGG	PUF60	ENSG00000179950	-5.021991572306309	[17]	[0]	-9	hSpCas9	negative selection	11236378
143817620	143817643	8	+	28162770	OCIAML5	viability	GCAGCTGCCACAGCAGCGGCAGG	PUF60	ENSG00000179950	-0.8520665708639967	[0]	[0]	-5	hSpCas9	negative selection	11236379
143817085	143817108	8	+	28162770	OCIAML5	viability	GGGTTCACCACTCCCACCGAGGG	PUF60	ENSG00000179950	-1.3602134745343224	[191]	[134]	-7	hSpCas9	negative selection	11236380
143821668	143821691	8	-	28162770	OCIAML5	viability	TCAGGCCAAGAAGTACGCCATGG	PUF60	ENSG00000179950	-5.889155889599217	[196]	[5]	-9	hSpCas9	negative selection	11236381
143821644	143821667	8	-	28162770	OCIAML5	viability	GCAGAGCATCAAGAGTGTGCTGG	PUF60	ENSG00000179950	-2.973081971825363	[260]	[59]	-8	hSpCas9	negative selection	11236382
143818256	143818279	8	+	28162770	EOL1	viability	GGGGACCTCATACTCCACGAAGG	PUF60	ENSG00000179950	-2.8828071504870696	[111]	[7]	-9	hSpCas9	negative selection	11405739
143821596	143821619	8	-	28162770	EOL1	viability	GCAGCAGCTCACCAACCTGCAGG	PUF60	ENSG00000179950	-0.3769162207571121	[349]	[141]	-3	hSpCas9	negative selection	11405740
143816909	143816932	8	-	28162770	EOL1	viability	GAAGCTGCTCCGCAAGCAGGAGG	PUF60	ENSG00000179950	-2.4740016049197404	[231]	[21]	-8	hSpCas9	negative selection	11405741
143821860	143821883	8	-	28162770	EOL1	viability	AGAGCACAGCCGCCAAGCTGGGG	PUF60	ENSG00000179950	-4.599014184486478	[45]	[0]	-9	hSpCas9	negative selection	11405742
143821829	143821852	8	-	28162770	EOL1	viability	CCTGACGCCCGAGCAGCAGGAGG	PUF60	ENSG00000179950	-2.308112985219741	[328]	[34]	-8	hSpCas9	negative selection	11405743
143817702	143817725	8	-	28162770	EOL1	viability	GGGTGGCCAGTACTTGCGGGTGG	PUF60	ENSG00000179950	-5.284905594058415	[73]	[0]	-9	hSpCas9	negative selection	11405744
143817620	143817643	8	+	28162770	EOL1	viability	GCAGCTGCCACAGCAGCGGCAGG	PUF60	ENSG00000179950	0.924547771570535	[0]	[0]	7	hSpCas9	negative selection	11405745
143817085	143817108	8	+	28162770	EOL1	viability	GGGTTCACCACTCCCACCGAGGG	PUF60	ENSG00000179950	-1.3023672084566074	[425]	[90]	-7	hSpCas9	negative selection	11405746
143821668	143821691	8	-	28162770	EOL1	viability	TCAGGCCAAGAAGTACGCCATGG	PUF60	ENSG00000179950	-5.292682944650134	[371]	[4]	-9	hSpCas9	negative selection	11405747
143821644	143821667	8	-	28162770	EOL1	viability	GCAGAGCATCAAGAGTGTGCTGG	PUF60	ENSG00000179950	0.10857971920822235	[293]	[166]	1	hSpCas9	negative selection	11405748
143818256	143818279	8	+	28162770	MOLM13	viability	GGGGACCTCATACTCCACGAAGG	PUF60	ENSG00000179950	-5.532110618455421	[63]	[0]	-9	hSpCas9	negative selection	11575105
143821596	143821619	8	-	28162770	MOLM13	viability	GCAGCAGCTCACCAACCTGCAGG	PUF60	ENSG00000179950	-2.0357730170747295	[413]	[72]	-7	hSpCas9	negative selection	11575106
143816909	143816932	8	-	28162770	MOLM13	viability	GAAGCTGCTCCGCAAGCAGGAGG	PUF60	ENSG00000179950	-2.8977600907721017	[133]	[12]	-8	hSpCas9	negative selection	11575107
143821860	143821883	8	-	28162770	MOLM13	viability	AGAGCACAGCCGCCAAGCTGGGG	PUF60	ENSG00000179950	-2.1468204625706298	[48]	[7]	-7	hSpCas9	negative selection	11575108
143821829	143821852	8	-	28162770	MOLM13	viability	CCTGACGCCCGAGCAGCAGGAGG	PUF60	ENSG00000179950	-1.7311819655572498	[224]	[48]	-7	hSpCas9	negative selection	11575109
143817702	143817725	8	-	28162770	MOLM13	viability	GGGTGGCCAGTACTTGCGGGTGG	PUF60	ENSG00000179950	-0.37164594626217484	[33]	[18]	-2	hSpCas9	negative selection	11575110
143817620	143817643	8	+	28162770	MOLM13	viability	GCAGCTGCCACAGCAGCGGCAGG	PUF60	ENSG00000179950	0.4678893815445777	[0]	[0]	3	hSpCas9	negative selection	11575111
143817085	143817108	8	+	28162770	MOLM13	viability	GGGTTCACCACTCCCACCGAGGG	PUF60	ENSG00000179950	-2.300103108242252	[469]	[68]	-8	hSpCas9	negative selection	11575112
143821668	143821691	8	-	28162770	MOLM13	viability	TCAGGCCAAGAAGTACGCCATGG	PUF60	ENSG00000179950	-6.94996313334132	[341]	[1]	-9	hSpCas9	negative selection	11575113
143821644	143821667	8	-	28162770	MOLM13	viability	GCAGAGCATCAAGAGTGTGCTGG	PUF60	ENSG00000179950	-3.5747549558639147	[411]	[24]	-8	hSpCas9	negative selection	11575114
143818256	143818279	8	+	28162770	HEL	viability	GGGGACCTCATACTCCACGAAGG	PUF60	ENSG00000179950	-5.766652104137345	[84]	[0]	-9	hSpCas9	negative selection	11744471
143821596	143821619	8	-	28162770	HEL	viability	GCAGCAGCTCACCAACCTGCAGG	PUF60	ENSG00000179950	0.08085994439224187	[340]	[230]	0	hSpCas9	negative selection	11744472
143816909	143816932	8	-	28162770	HEL	viability	GAAGCTGCTCCGCAAGCAGGAGG	PUF60	ENSG00000179950	-1.835308464804287	[155]	[27]	-7	hSpCas9	negative selection	11744473
143821860	143821883	8	-	28162770	HEL	viability	AGAGCACAGCCGCCAAGCTGGGG	PUF60	ENSG00000179950	-2.2503459640831314	[51]	[6]	-8	hSpCas9	negative selection	11744474
143821829	143821852	8	-	28162770	HEL	viability	CCTGACGCCCGAGCAGCAGGAGG	PUF60	ENSG00000179950	-1.0866135780559738	[188]	[56]	-6	hSpCas9	negative selection	11744475
143817702	143817725	8	-	28162770	HEL	viability	GGGTGGCCAGTACTTGCGGGTGG	PUF60	ENSG00000179950	-4.81669278663694	[43]	[0]	-9	hSpCas9	negative selection	11744476
143817620	143817643	8	+	28162770	HEL	viability	GCAGCTGCCACAGCAGCGGCAGG	PUF60	ENSG00000179950	-0.3572611679996429	[1]	[0]	-2	hSpCas9	negative selection	11744477
143817085	143817108	8	+	28162770	HEL	viability	GGGTTCACCACTCCCACCGAGGG	PUF60	ENSG00000179950	-1.494019305506756	[386]	[87]	-7	hSpCas9	negative selection	11744478
143821668	143821691	8	-	28162770	HEL	viability	TCAGGCCAAGAAGTACGCCATGG	PUF60	ENSG00000179950	-3.021581460334083	[354]	[27]	-8	hSpCas9	negative selection	11744479
143821644	143821667	8	-	28162770	HEL	viability	GCAGAGCATCAAGAGTGTGCTGG	PUF60	ENSG00000179950	-1.2622646540638962	[381]	[101]	-6	hSpCas9	negative selection	11744480
143818256	143818279	8	+	28162770	MV411	viability	GGGGACCTCATACTCCACGAAGG	PUF60	ENSG00000179950	-5.635205498579066	[58]	[0]	-9	hSpCas9	negative selection	11913837
143821596	143821619	8	-	28162770	MV411	viability	GCAGCAGCTCACCAACCTGCAGG	PUF60	ENSG00000179950	-0.7885417463227912	[202]	[98]	-5	hSpCas9	negative selection	11913838
143816909	143816932	8	-	28162770	MV411	viability	GAAGCTGCTCCGCAAGCAGGAGG	PUF60	ENSG00000179950	-5.494029435618372	[106]	[1]	-9	hSpCas9	negative selection	11913839
143821860	143821883	8	-	28162770	MV411	viability	AGAGCACAGCCGCCAAGCTGGGG	PUF60	ENSG00000179950	-4.559917371274828	[27]	[0]	-9	hSpCas9	negative selection	11913840
143821829	143821852	8	-	28162770	MV411	viability	CCTGACGCCCGAGCAGCAGGAGG	PUF60	ENSG00000179950	-2.8568991090319606	[171]	[19]	-9	hSpCas9	negative selection	11913841
143817702	143817725	8	-	28162770	MV411	viability	GGGTGGCCAGTACTTGCGGGTGG	PUF60	ENSG00000179950	-2.337524949938381	[71]	[11]	-8	hSpCas9	negative selection	11913842
143817620	143817643	8	+	28162770	MV411	viability	GCAGCTGCCACAGCAGCGGCAGG	PUF60	ENSG00000179950	-0.7525624492172245	[1]	[0]	-5	hSpCas9	negative selection	11913843
143817085	143817108	8	+	28162770	MV411	viability	GGGTTCACCACTCCCACCGAGGG	PUF60	ENSG00000179950	-2.5386225929116004	[268]	[38]	-8	hSpCas9	negative selection	11913844
143821668	143821691	8	-	28162770	MV411	viability	TCAGGCCAAGAAGTACGCCATGG	PUF60	ENSG00000179950	-3.211994067854522	[274]	[24]	-9	hSpCas9	negative selection	11913845
143821644	143821667	8	-	28162770	MV411	viability	GCAGAGCATCAAGAGTGTGCTGG	PUF60	ENSG00000179950	-0.5908113792206124	[235]	[131]	-4	hSpCas9	negative selection	11913846
143818256	143818279	8	+	28162770	MONOMAC1	viability	GGGGACCTCATACTCCACGAAGG	PUF60	ENSG00000179950	-4.004391769117158	[41]	[2]	-9	hSpCas9	negative selection	12083203
143821596	143821619	8	-	28162770	MONOMAC1	viability	GCAGCAGCTCACCAACCTGCAGG	PUF60	ENSG00000179950	-0.653415141719297	[176]	[128]	-5	hSpCas9	negative selection	12083204
143816909	143816932	8	-	28162770	MONOMAC1	viability	GAAGCTGCTCCGCAAGCAGGAGG	PUF60	ENSG00000179950	-3.6934626731790523	[78]	[6]	-9	hSpCas9	negative selection	12083205
143821860	143821883	8	-	28162770	MONOMAC1	viability	AGAGCACAGCCGCCAAGCTGGGG	PUF60	ENSG00000179950	-1.419429268396002	[13]	[5]	-8	hSpCas9	negative selection	12083206
143821829	143821852	8	-	28162770	MONOMAC1	viability	CCTGACGCCCGAGCAGCAGGAGG	PUF60	ENSG00000179950	-2.3914148922264054	[118]	[25]	-9	hSpCas9	negative selection	12083207
143817702	143817725	8	-	28162770	MONOMAC1	viability	GGGTGGCCAGTACTTGCGGGTGG	PUF60	ENSG00000179950	-2.9132438810589623	[45]	[6]	-9	hSpCas9	negative selection	12083208
143817620	143817643	8	+	28162770	MONOMAC1	viability	GCAGCTGCCACAGCAGCGGCAGG	PUF60	ENSG00000179950	-0.19703684705955382	[0]	[0]	-2	hSpCas9	negative selection	12083209
143817085	143817108	8	+	28162770	MONOMAC1	viability	GGGTTCACCACTCCCACCGAGGG	PUF60	ENSG00000179950	-2.320419262564836	[182]	[41]	-9	hSpCas9	negative selection	12083210
143821668	143821691	8	-	28162770	MONOMAC1	viability	TCAGGCCAAGAAGTACGCCATGG	PUF60	ENSG00000179950	-0.6903688723151417	[182]	[129]	-5	hSpCas9	negative selection	12083211
143821644	143821667	8	-	28162770	MONOMAC1	viability	GCAGAGCATCAAGAGTGTGCTGG	PUF60	ENSG00000179950	1.4156173875306506	[171]	[525]	9	hSpCas9	negative selection	12083212
143818256	143818279	8	+	28162770	OCIAML2	viability	GGGGACCTCATACTCCACGAAGG	PUF60	ENSG00000179950	-2.98520299807192	[9]	[6]	-9	hSpCas9	negative selection	12252569
143821596	143821619	8	-	28162770	OCIAML2	viability	GCAGCAGCTCACCAACCTGCAGG	PUF60	ENSG00000179950	-1.286205254104734	[43]	[99]	-7	hSpCas9	negative selection	12252570
143816909	143816932	8	-	28162770	OCIAML2	viability	GAAGCTGCTCCGCAAGCAGGAGG	PUF60	ENSG00000179950	-3.869179201732436	[28]	[10]	-9	hSpCas9	negative selection	12252571
143821860	143821883	8	-	28162770	OCIAML2	viability	AGAGCACAGCCGCCAAGCTGGGG	PUF60	ENSG00000179950	-2.318626731797111	[8]	[9]	-8	hSpCas9	negative selection	12252572
143821829	143821852	8	-	28162770	OCIAML2	viability	CCTGACGCCCGAGCAGCAGGAGG	PUF60	ENSG00000179950	-2.2713210170187548	[26]	[30]	-8	hSpCas9	negative selection	12252573
143817702	143817725	8	-	28162770	OCIAML2	viability	GGGTGGCCAGTACTTGCGGGTGG	PUF60	ENSG00000179950	-2.733664231075955	[5]	[4]	-9	hSpCas9	negative selection	12252574
143817620	143817643	8	+	28162770	OCIAML2	viability	GCAGCTGCCACAGCAGCGGCAGG	PUF60	ENSG00000179950	-2.4706298252421615	[0]	[0]	-8	hSpCas9	negative selection	12252575
143817085	143817108	8	+	28162770	OCIAML2	viability	GGGTTCACCACTCCCACCGAGGG	PUF60	ENSG00000179950	-1.816126391267928	[53]	[84]	-8	hSpCas9	negative selection	12252576
143821668	143821691	8	-	28162770	OCIAML2	viability	TCAGGCCAAGAAGTACGCCATGG	PUF60	ENSG00000179950	-2.4171905662807007	[52]	[54]	-8	hSpCas9	negative selection	12252577
143821644	143821667	8	-	28162770	OCIAML2	viability	GCAGAGCATCAAGAGTGTGCTGG	PUF60	ENSG00000179950	-1.9890969141764105	[52]	[73]	-8	hSpCas9	negative selection	12252578
143818256	143818279	8	+	28162770	OCIAML3	viability	GGGGACCTCATACTCCACGAAGG	PUF60	ENSG00000179950	-3.272079545436801	[15]	[4]	-9	hSpCas9	negative selection	12421935
143821596	143821619	8	-	28162770	OCIAML3	viability	GCAGCAGCTCACCAACCTGCAGG	PUF60	ENSG00000179950	-0.2760375590054841	[72]	[181]	-2	hSpCas9	negative selection	12421936
143816909	143816932	8	-	28162770	OCIAML3	viability	GAAGCTGCTCCGCAAGCAGGAGG	PUF60	ENSG00000179950	-2.94193094374447	[27]	[10]	-9	hSpCas9	negative selection	12421937
143821860	143821883	8	-	28162770	OCIAML3	viability	AGAGCACAGCCGCCAAGCTGGGG	PUF60	ENSG00000179950	-4.9159357352115265	[9]	[0]	-9	hSpCas9	negative selection	12421938
143821829	143821852	8	-	28162770	OCIAML3	viability	CCTGACGCCCGAGCAGCAGGAGG	PUF60	ENSG00000179950	-0.8636147000814434	[43]	[72]	-6	hSpCas9	negative selection	12421939
143817702	143817725	8	-	28162770	OCIAML3	viability	GGGTGGCCAGTACTTGCGGGTGG	PUF60	ENSG00000179950	-2.731511164074098	[10]	[4]	-9	hSpCas9	negative selection	12421940
143817620	143817643	8	+	28162770	OCIAML3	viability	GCAGCTGCCACAGCAGCGGCAGG	PUF60	ENSG00000179950	-1.594007640324163	[0]	[0]	-8	hSpCas9	negative selection	12421941
143817085	143817108	8	+	28162770	OCIAML3	viability	GGGTTCACCACTCCCACCGAGGG	PUF60	ENSG00000179950	-1.748041268996584	[78]	[70]	-8	hSpCas9	negative selection	12421942
143821668	143821691	8	-	28162770	OCIAML3	viability	TCAGGCCAAGAAGTACGCCATGG	PUF60	ENSG00000179950	-4.278505814596234	[89]	[13]	-9	hSpCas9	negative selection	12421943
143821644	143821667	8	-	28162770	OCIAML3	viability	GCAGAGCATCAAGAGTGTGCTGG	PUF60	ENSG00000179950	-1.0143394392725202	[90]	[135]	-6	hSpCas9	negative selection	12421944