| 31201617 | 31201640 | 16 | + | 26627737 | DLD1 | viability | ACTGGGACTCCCTTAGGGCCTGG | PYCARD | ENSG00000103490 | -1.303263879937926 | [366] | [22,125,0] | -8 | hSpCas9 | negative selection | 793895 | 31201797 | 31201820 | 16 | - | 26627737 | DLD1 | viability | CCGGGCTGCGCTTATCGCGAGGG | PYCARD | ENSG00000103490 | -0.8387052959188557 | [834] | [253,161,38] | -7 | hSpCas9 | negative selection | 793896 | 31201617 | 31201640 | 16 | + | 26627737 | GBM cells | viability after 5 days | ACTGGGACTCCCTTAGGGCCTGG | PYCARD | ENSG00000103490 | 0.1514559069018372 | [114] | [63,72] | 2 | hSpCas9 | negative selection | 876210 | 31201797 | 31201820 | 16 | - | 26627737 | GBM cells | viability after 5 days | CCGGGCTGCGCTTATCGCGAGGG | PYCARD | ENSG00000103490 | 0.3369189357116559 | [295] | [168,231] | 5 | hSpCas9 | negative selection | 876211 | 31201617 | 31201640 | 16 | + | 26627737 | GBM cells | viability after 13 days | ACTGGGACTCCCTTAGGGCCTGG | PYCARD | ENSG00000103490 | 1.0628923974329212 | [114] | [147,115] | 9 | hSpCas9 | negative selection | 958525 | 31201797 | 31201820 | 16 | - | 26627737 | GBM cells | viability after 13 days | CCGGGCTGCGCTTATCGCGAGGG | PYCARD | ENSG00000103490 | 0.7355688855170059 | [295] | [262,270] | 8 | hSpCas9 | negative selection | 958526 | 31201617 | 31201640 | 16 | + | 26627737 | GBM cells | viability after 21 days | ACTGGGACTCCCTTAGGGCCTGG | PYCARD | ENSG00000103490 | 1.2530508441245225 | [114] | [150,146] | 9 | hSpCas9 | negative selection | 1040840 | 31201797 | 31201820 | 16 | - | 26627737 | GBM cells | viability after 21 days | CCGGGCTGCGCTTATCGCGAGGG | PYCARD | ENSG00000103490 | 0.649204399427566 | [295] | [270,234] | 6 | hSpCas9 | negative selection | 1040841 | 31201617 | 31201640 | 16 | + | 26627737 | RPE1 | viability after 9 days | ACTGGGACTCCCTTAGGGCCTGG | PYCARD | ENSG00000103490 | -1.7851808571774144 | [186] | [9,25] | -8 | hSpCas9 | negative selection | 1123155 | 31201797 | 31201820 | 16 | - | 26627737 | RPE1 | viability after 9 days | CCGGGCTGCGCTTATCGCGAGGG | PYCARD | ENSG00000103490 | -0.18469021457522833 | [1184] | [311,344] | -1 | hSpCas9 | negative selection | 1123156 | 31201617 | 31201640 | 16 | + | 26627737 | RPE1 | viability after 12 days | ACTGGGACTCCCTTAGGGCCTGG | PYCARD | ENSG00000103490 | 0.3671388597827636 | [186] | [74,53] | 2 | hSpCas9 | negative selection | 1205470 | 31201797 | 31201820 | 16 | - | 26627737 | RPE1 | viability after 12 days | CCGGGCTGCGCTTATCGCGAGGG | PYCARD | ENSG00000103490 | -1.1394916273942117 | [1184] | [110,179] | -7 | hSpCas9 | negative selection | 1205471 | 31201617 | 31201640 | 16 | + | 26627737 | RPE1 | viability after 15 days | ACTGGGACTCCCTTAGGGCCTGG | PYCARD | ENSG00000103490 | -1.3081713778031805 | [186] | [0,40] | -7 | hSpCas9 | negative selection | 1287785 | 31201797 | 31201820 | 16 | - | 26627737 | RPE1 | viability after 15 days | CCGGGCTGCGCTTATCGCGAGGG | PYCARD | ENSG00000103490 | -0.6803144944205431 | [1184] | [198,218] | -4 | hSpCas9 | negative selection | 1287786 | 31201617 | 31201640 | 16 | + | 26627737 | RPE1 | viability after 18 days | ACTGGGACTCCCTTAGGGCCTGG | PYCARD | ENSG00000103490 | -1.07625771596756 | [186] | [21,25] | -6 | hSpCas9 | negative selection | 1370100 | 31201797 | 31201820 | 16 | - | 26627737 | RPE1 | viability after 18 days | CCGGGCTGCGCTTATCGCGAGGG | PYCARD | ENSG00000103490 | -1.5435023436218045 | [1184] | [71,149] | -7 | hSpCas9 | negative selection | 1370101 | 31201617 | 31201640 | 16 | + | 26627737 | HeLa | viability after 8 days | ACTGGGACTCCCTTAGGGCCTGG | PYCARD | ENSG00000103490 | -0.3679842937804342 | [235] | [54,108,69] | -4 | hSpCas9 | negative selection | 1452415 | 31201797 | 31201820 | 16 | - | 26627737 | HeLa | viability after 8 days | CCGGGCTGCGCTTATCGCGAGGG | PYCARD | ENSG00000103490 | -0.9007463412469368 | [910] | [259,286,107] | -7 | hSpCas9 | negative selection | 1452416 | 31201617 | 31201640 | 16 | + | 26627737 | HeLa | viability after 12 days | ACTGGGACTCCCTTAGGGCCTGG | PYCARD | ENSG00000103490 | -0.25427083838243747 | [235] | [54,133,49] | -2 | hSpCas9 | negative selection | 1534730 | 31201797 | 31201820 | 16 | - | 26627737 | HeLa | viability after 12 days | CCGGGCTGCGCTTATCGCGAGGG | PYCARD | ENSG00000103490 | -1.2771021264941573 | [910] | [177,76,219] | -8 | hSpCas9 | negative selection | 1534731 | 31201617 | 31201640 | 16 | + | 26627737 | HeLa | viability after 15 days | ACTGGGACTCCCTTAGGGCCTGG | PYCARD | ENSG00000103490 | 0.8833342349386488 | [235] | [288,90,147] | 6 | hSpCas9 | negative selection | 1617045 | 31201797 | 31201820 | 16 | - | 26627737 | HeLa | viability after 15 days | CCGGGCTGCGCTTATCGCGAGGG | PYCARD | ENSG00000103490 | -0.9940353287356151 | [910] | [194,291,61] | -7 | hSpCas9 | negative selection | 1617046 | 31201617 | 31201640 | 16 | + | 26627737 | HeLa | viability after 18 days | ACTGGGACTCCCTTAGGGCCTGG | PYCARD | ENSG00000103490 | 0.8605992417473107 | [235] | [187,75,147] | 6 | hSpCas9 | negative selection | 1699360 | 31201797 | 31201820 | 16 | - | 26627737 | HeLa | viability after 18 days | CCGGGCTGCGCTTATCGCGAGGG | PYCARD | ENSG00000103490 | -0.9441824495123962 | [910] | [140,244,61] | -7 | hSpCas9 | negative selection | 1699361 | 31201617 | 31201640 | 16 | + | 26627737 | HCT116 | viability after 6 days | ACTGGGACTCCCTTAGGGCCTGG | PYCARD | ENSG00000103490 | 0.9521336135536499 | [322] | [250,13] | 5 | hSpCas9 | negative selection | 1781675 | 31201797 | 31201820 | 16 | - | 26627737 | HCT116 | viability after 6 days | CCGGGCTGCGCTTATCGCGAGGG | PYCARD | ENSG00000103490 | 0.8961153868588548 | [862] | [256,249] | 5 | hSpCas9 | negative selection | 1781676 | 31201617 | 31201640 | 16 | + | 26627737 | HCT116 | viability after 8 days | ACTGGGACTCCCTTAGGGCCTGG | PYCARD | ENSG00000103490 | 0.7420086011002587 | [78] | [41,113,61] | 7 | hSpCas9 | negative selection | 1863990 | 31201797 | 31201820 | 16 | - | 26627737 | HCT116 | viability after 8 days | CCGGGCTGCGCTTATCGCGAGGG | PYCARD | ENSG00000103490 | -0.6170883687405953 | [592] | [183,273,180] | -6 | hSpCas9 | negative selection | 1863991 | 31201617 | 31201640 | 16 | + | 26627737 | HCT116 | viability after 9 days | ACTGGGACTCCCTTAGGGCCTGG | PYCARD | ENSG00000103490 | -0.07364127188199032 | [322] | [172,9] | 0 | hSpCas9 | negative selection | 1946305 | 31201797 | 31201820 | 16 | - | 26627737 | HCT116 | viability after 9 days | CCGGGCTGCGCTTATCGCGAGGG | PYCARD | ENSG00000103490 | 0.35810547023579764 | [862] | [186,380] | 2 | hSpCas9 | negative selection | 1946306 | 31201617 | 31201640 | 16 | + | 26627737 | HCT116 | viability after 12 days | ACTGGGACTCCCTTAGGGCCTGG | PYCARD | ENSG00000103490 | 1.9706969024174195 | [78] | [65,175,254] | 9 | hSpCas9 | negative selection | 2028620 | 31201797 | 31201820 | 16 | - | 26627737 | HCT116 | viability after 12 days | CCGGGCTGCGCTTATCGCGAGGG | PYCARD | ENSG00000103490 | -0.17264747447015316 | [592] | [210,184,436] | -2 | hSpCas9 | negative selection | 2028621 | 31201617 | 31201640 | 16 | + | 26627737 | HCT116 | viability after 15 days | ACTGGGACTCCCTTAGGGCCTGG | PYCARD | ENSG00000103490 | 1.190718846572754 | [78] | [74,110,120] | 8 | hSpCas9 | negative selection | 2110935 | 31201797 | 31201820 | 16 | - | 26627737 | HCT116 | viability after 15 days | CCGGGCTGCGCTTATCGCGAGGG | PYCARD | ENSG00000103490 | -0.40199666255035615 | [592] | [239,185,343] | -4 | hSpCas9 | negative selection | 2110936 | 31201617 | 31201640 | 16 | + | 26627737 | HCT116 | viability after 18 days | ACTGGGACTCCCTTAGGGCCTGG | PYCARD | ENSG00000103490 | 1.2444486495836105 | [78] | [121,72,76] | 8 | hSpCas9 | negative selection | 2193250 | 31201797 | 31201820 | 16 | - | 26627737 | HCT116 | viability after 18 days | CCGGGCTGCGCTTATCGCGAGGG | PYCARD | ENSG00000103490 | -0.11188677921913293 | [592] | [177,282,336] | -1 | hSpCas9 | negative selection | 2193251 | 31201797 | 31201820 | | + | 24336571 | A375 | resistance to PLX after 7 days | CCCTCGCGATAAGCGCAGCCCGG | PYCARD | ENSG00000103490 | 0.12482039798315508 | [15,15] | [17,15] | 4 | hSpCas9 | positive selection | 3139083 | 31201780 | 31201803 | | - | 24336571 | A375 | resistance to PLX after 7 days | CGAGGGTCACAAACGTTGAGTGG | PYCARD | ENSG00000103490 | 0.17441061729307605 | [15,14] | [15,18] | 5 | hSpCas9 | positive selection | 3139084 | 31201797 | 31201820 | | + | 24336571 | A375 | resistance to PLX after 14 days | CCCTCGCGATAAGCGCAGCCCGG | PYCARD | ENSG00000103490 | 0.09696033530008619 | [18,18] | [8,9] | 1 | hSpCas9 | positive selection | 3196876 | 31201780 | 31201803 | | - | 24336571 | A375 | resistance to PLX after 14 days | CGAGGGTCACAAACGTTGAGTGG | PYCARD | ENSG00000103490 | 0.48993790903311873 | [14,11] | [9,6] | 4 | hSpCas9 | positive selection | 3196877 | 31201797 | 31201820 | | + | 24336571 | A375 | viability after 7 days | CCCTCGCGATAAGCGCAGCCCGG | PYCARD | ENSG00000103490 | -0.16595243689274963 | [18] | [15,15] | -2 | hSpCas9 | negative selection | 3254669 | 31201780 | 31201803 | | - | 24336571 | A375 | viability after 7 days | CGAGGGTCACAAACGTTGAGTGG | PYCARD | ENSG00000103490 | -0.33722172836760433 | [20] | [15,14] | -5 | hSpCas9 | negative selection | 3254670 | 31201797 | 31201820 | | + | 24336571 | A375 | viability after 14 days | CCCTCGCGATAAGCGCAGCCCGG | PYCARD | ENSG00000103490 | 0.12220719307475653 | [18] | [18,18] | 1 | hSpCas9 | negative selection | 3312462 | 31201780 | 31201803 | | - | 24336571 | A375 | viability after 14 days | CGAGGGTCACAAACGTTGAGTGG | PYCARD | ENSG00000103490 | -0.5081651896468785 | [20] | [14,11] | -6 | hSpCas9 | negative selection | 3312463 | 31201797 | 31201820 | 16 | + | 27383988 | 293T | resistance to West Nile virus (flavivirus) | CCCTCGCGATAAGCGCAGCCCGG | PYCARD | ENSG00000103490 | 0.8143827155971068 | [86,86] | [0,0] | 4 | hSpCas9 | positive selection | 3388457 | 31201797 | 31201820 | 16 | + | 26780180 | A375 | viability | CCCTCGCGATAAGCGCAGCCCGG | PYCARD | ENSG00000103490 | 1.23081835946479 | [] | [] | 6 | hSpCas9 | negative selection | 3986256 | 31201780 | 31201803 | 16 | - | 26780180 | A375 | viability | CGAGGGTCACAAACGTTGAGTGG | PYCARD | ENSG00000103490 | 1.26434781734997 | [] | [] | 6 | hSpCas9 | negative selection | 3986257 | 31201797 | 31201820 | 16 | + | 26780180 | HT29 | viability (GeCKOv2 library) | CCCTCGCGATAAGCGCAGCCCGG | PYCARD | ENSG00000103490 | 1.68670802633239 | [] | [] | 8 | hSpCas9 | negative selection | 4094222 | 31201780 | 31201803 | 16 | - | 26780180 | HT29 | viability (GeCKOv2 library) | CGAGGGTCACAAACGTTGAGTGG | PYCARD | ENSG00000103490 | 1.08612968435839 | [] | [] | 5 | hSpCas9 | negative selection | 4094223 | 31201797 | 31201820 | 16 | + | 26780180 | A375 | resistance to vemurafenib (GeCKOv1 lentiCRISPRv1) | CCCTCGCGATAAGCGCAGCCCGG | PYCARD | ENSG00000103490 | -0.17278732636612879 | [4] | [1,3] | -4 | hSpCas9 | positive selection | 4164386 | 31201780 | 31201803 | 16 | - | 26780180 | A375 | resistance to vemurafenib (GeCKOv1 lentiCRISPRv1) | CGAGGGTCACAAACGTTGAGTGG | PYCARD | ENSG00000103490 | -0.13954557669561116 | [4] | [1,3] | -3 | hSpCas9 | positive selection | 4164388 | 31201797 | 31201820 | 16 | + | 26780180 | A375 | resistance to vemurafenib (GeCKOv1 lentiGuide) | CCCTCGCGATAAGCGCAGCCCGG | PYCARD | ENSG00000103490 | 0.9220105730160115 | [4] | [5,3,2,3] | 6 | hSpCas9 | positive selection | 4228408 | 31201780 | 31201803 | 16 | - | 26780180 | A375 | resistance to vemurafenib (GeCKOv1 lentiGuide) | CGAGGGTCACAAACGTTGAGTGG | PYCARD | ENSG00000103490 | -0.15157087716367573 | [4] | [0,0,5,0] | -2 | hSpCas9 | positive selection | 4228410 | 31201780 | 31201803 | 16 | - | 26780180 | A375 | resistance to vemurafenib (GeCKOv2 lentiGuide) | CGAGGGTCACAAACGTTGAGTGG | PYCARD | ENSG00000103490 | 0.33597134634816983 | [2] | [1,2] | 6 | hSpCas9 | positive selection | 4293303 | 31201797 | 31201820 | 16 | + | 26780180 | A375 | resistance to vemurafenib (GeCKOv2 lentiGuide) | CCCTCGCGATAAGCGCAGCCCGG | PYCARD | ENSG00000103490 | -0.07844158893033026 | [2] | [1,0] | -1 | hSpCas9 | positive selection | 4357559 | 31201773 | 31201795 | 16 | - | 27760321 | OCIAML3 | viability | ACAAACGTTGAGTGGCTGCTGG | PYCARD | ENSG00000103490 | 0.02194334127253561 | [816,720] | [579,647] | 0 | hSpCas9 | negative selection | 4432231 | 31201798 | 31201820 | 16 | + | 27760321 | OCIAML3 | viability | CCTCGCGATAAGCGCAGCCCGG | PYCARD | ENSG00000103490 | 0.6593937884495078 | [534,434] | [506,711] | 7 | hSpCas9 | negative selection | 4432232 | 31201816 | 31201838 | 16 | - | 27760321 | OCIAML3 | viability | GCACTTTATAGACCAGCACCGG | PYCARD | ENSG00000103490 | 0.5647350548058847 | [472,423] | [479,567] | 6 | hSpCas9 | negative selection | 4432233 | 31201773 | 31201795 | 16 | - | 27760321 | OCIAML2 | viability | ACAAACGTTGAGTGGCTGCTGG | PYCARD | ENSG00000103490 | -0.30733361326644437 | [816,720] | [383,656] | -4 | hSpCas9 | negative selection | 4515694 | 31201798 | 31201820 | 16 | + | 27760321 | OCIAML2 | viability | CCTCGCGATAAGCGCAGCCCGG | PYCARD | ENSG00000103490 | 0.4093059863231827 | [534,434] | [403,668] | 5 | hSpCas9 | negative selection | 4515695 | 31201816 | 31201838 | 16 | - | 27760321 | OCIAML2 | viability | GCACTTTATAGACCAGCACCGG | PYCARD | ENSG00000103490 | 0.42220312010117544 | [472,423] | [441,542] | 6 | hSpCas9 | negative selection | 4515696 | 31201773 | 31201795 | 16 | - | 27760321 | MV411 | viability | ACAAACGTTGAGTGGCTGCTGG | PYCARD | ENSG00000103490 | 0.5706059477593487 | [816,720] | [597,983] | 4 | hSpCas9 | negative selection | 4599157 | 31201798 | 31201820 | 16 | + | 27760321 | MV411 | viability | CCTCGCGATAAGCGCAGCCCGG | PYCARD | ENSG00000103490 | 1.3066692853806126 | [534,434] | [1042,403] | 8 | hSpCas9 | negative selection | 4599158 | 31201816 | 31201838 | 16 | - | 27760321 | MV411 | viability | GCACTTTATAGACCAGCACCGG | PYCARD | ENSG00000103490 | 0.32117466364665403 | [472,423] | [272,513] | 2 | hSpCas9 | negative selection | 4599159 | 31201773 | 31201795 | 16 | - | 27760321 | HL60 | viability | ACAAACGTTGAGTGGCTGCTGG | PYCARD | ENSG00000103490 | 1.01115764833343 | [816,720] | [891,1657] | 9 | hSpCas9 | negative selection | 4682620 | 31201798 | 31201820 | 16 | + | 27760321 | HL60 | viability | CCTCGCGATAAGCGCAGCCCGG | PYCARD | ENSG00000103490 | -0.14081860178866115 | [534,434] | [389,322] | -1 | hSpCas9 | negative selection | 4682621 | 31201816 | 31201838 | 16 | - | 27760321 | HL60 | viability | GCACTTTATAGACCAGCACCGG | PYCARD | ENSG00000103490 | 0.02276153380106884 | [472,423] | [379,362] | 0 | hSpCas9 | negative selection | 4682622 | 31201773 | 31201795 | 16 | - | 27760321 | HT1080 | viability | ACAAACGTTGAGTGGCTGCTGG | PYCARD | ENSG00000103490 | 1.4993539671636125 | [720,562] | [787,651] | 7 | hSpCas9 | negative selection | 4766083 | 31201798 | 31201820 | 16 | + | 27760321 | HT1080 | viability | CCTCGCGATAAGCGCAGCCCGG | PYCARD | ENSG00000103490 | 0.20996287216134574 | [434,339] | [179,176] | 1 | hSpCas9 | negative selection | 4766084 | 31201816 | 31201838 | 16 | - | 27760321 | HT1080 | viability | GCACTTTATAGACCAGCACCGG | PYCARD | ENSG00000103490 | 0.4738825109890487 | [423,330] | [68,361] | 2 | hSpCas9 | negative selection | 4766085 | 31201773 | 31201795 | 16 | - | 27760321 | HT29 | viability after 7 days | ACAAACGTTGAGTGGCTGCTGG | PYCARD | ENSG00000103490 | -0.24626326543396282 | [720,562] | [719,572,793] | -4 | hSpCas9 | negative selection | 4849546 | 31201798 | 31201820 | 16 | + | 27760321 | HT29 | viability after 7 days | CCTCGCGATAAGCGCAGCCCGG | PYCARD | ENSG00000103490 | 0.45262628768839 | [434,339] | [864,435,766] | 7 | hSpCas9 | negative selection | 4849547 | 31201816 | 31201838 | 16 | - | 27760321 | HT29 | viability after 7 days | GCACTTTATAGACCAGCACCGG | PYCARD | ENSG00000103490 | 0.19353742680730385 | [423,330] | [718,422,545] | 3 | hSpCas9 | negative selection | 4849548 | 31201773 | 31201795 | 16 | - | 27760321 | HT29 | viability after 25 days | ACAAACGTTGAGTGGCTGCTGG | PYCARD | ENSG00000103490 | 0.04929380829583285 | [720,562] | [820,645,810] | 0 | hSpCas9 | negative selection | 4933009 | 31201798 | 31201820 | 16 | + | 27760321 | HT29 | viability after 25 days | CCTCGCGATAAGCGCAGCCCGG | PYCARD | ENSG00000103490 | 0.8296740902694864 | [434,339] | [698,618,1077] | 8 | hSpCas9 | negative selection | 4933010 | 31201816 | 31201838 | 16 | - | 27760321 | HT29 | viability after 25 days | GCACTTTATAGACCAGCACCGG | PYCARD | ENSG00000103490 | 0.020259136085299306 | [423,330] | [443,485,374] | 0 | hSpCas9 | negative selection | 4933011 | 31201773 | 31201795 | 16 | - | 27760321 | HT29 | viability after 22 days | ACAAACGTTGAGTGGCTGCTGG | PYCARD | ENSG00000103490 | 0.16996000239424425 | [720,562] | [962,652,885] | 1 | hSpCas9 | negative selection | 5016472 | 31201798 | 31201820 | 16 | + | 27760321 | HT29 | viability after 22 days | CCTCGCGATAAGCGCAGCCCGG | PYCARD | ENSG00000103490 | 0.6627748576967015 | [434,339] | [817,471,835] | 7 | hSpCas9 | negative selection | 5016473 | 31201816 | 31201838 | 16 | - | 27760321 | HT29 | viability after 22 days | GCACTTTATAGACCAGCACCGG | PYCARD | ENSG00000103490 | 0.1760962989066294 | [423,330] | [493,509,474] | 1 | hSpCas9 | negative selection | 5016474 | 31201773 | 31201795 | 16 | - | 27760321 | HT29 | viability after 19 days | ACAAACGTTGAGTGGCTGCTGG | PYCARD | ENSG00000103490 | -0.1526305217193903 | [720,562] | [816,852,339] | -1 | hSpCas9 | negative selection | 5099935 | 31201798 | 31201820 | 16 | + | 27760321 | HT29 | viability after 19 days | CCTCGCGATAAGCGCAGCCCGG | PYCARD | ENSG00000103490 | 1.2716442811258497 | [434,339] | [1291,662,1269] | 9 | hSpCas9 | negative selection | 5099936 | 31201816 | 31201838 | 16 | - | 27760321 | HT29 | viability after 19 days | GCACTTTATAGACCAGCACCGG | PYCARD | ENSG00000103490 | -0.33890075330585545 | [423,330] | [563,271,215] | -3 | hSpCas9 | negative selection | 5099937 | 31201773 | 31201795 | 16 | - | 27760321 | HT29 | viability after 16 days | ACAAACGTTGAGTGGCTGCTGG | PYCARD | ENSG00000103490 | 0.2573949056731888 | [720,562] | [910,995,669] | 3 | hSpCas9 | negative selection | 5183398 | 31201798 | 31201820 | 16 | + | 27760321 | HT29 | viability after 16 days | CCTCGCGATAAGCGCAGCCCGG | PYCARD | ENSG00000103490 | 0.7249954787429601 | [434,339] | [1310,371,531] | 8 | hSpCas9 | negative selection | 5183399 | 31201816 | 31201838 | 16 | - | 27760321 | HT29 | viability after 16 days | GCACTTTATAGACCAGCACCGG | PYCARD | ENSG00000103490 | 0.5969473845101154 | [423,330] | [790,321,825] | 7 | hSpCas9 | negative selection | 5183400 | 31201773 | 31201795 | 16 | - | 27760321 | HT29 | viability after 13 days | ACAAACGTTGAGTGGCTGCTGG | PYCARD | ENSG00000103490 | -0.010298815365880842 | [720,562] | [890,671,659] | 0 | hSpCas9 | negative selection | 5266861 | 31201798 | 31201820 | 16 | + | 27760321 | HT29 | viability after 13 days | CCTCGCGATAAGCGCAGCCCGG | PYCARD | ENSG00000103490 | 0.796966243537762 | [434,339] | [875,719,748] | 9 | hSpCas9 | negative selection | 5266862 | 31201816 | 31201838 | 16 | - | 27760321 | HT29 | viability after 13 days | GCACTTTATAGACCAGCACCGG | PYCARD | ENSG00000103490 | 0.16315456630716343 | [423,330] | [494,535,442] | 2 | hSpCas9 | negative selection | 5266863 | 31201773 | 31201795 | 16 | - | 27760321 | HT29 | viability after 10 days | ACAAACGTTGAGTGGCTGCTGG | PYCARD | ENSG00000103490 | 0.14790426748534158 | [720,562] | [548,773,1327] | 2 | hSpCas9 | negative selection | 5350324 | 31201798 | 31201820 | 16 | + | 27760321 | HT29 | viability after 10 days | CCTCGCGATAAGCGCAGCCCGG | PYCARD | ENSG00000103490 | 0.5531119725547109 | [434,339] | [671,812,648] | 7 | hSpCas9 | negative selection | 5350325 | 31201816 | 31201838 | 16 | - | 27760321 | HT29 | viability after 10 days | GCACTTTATAGACCAGCACCGG | PYCARD | ENSG00000103490 | 0.04133244205549666 | [423,330] | [545,356,546] | 0 | hSpCas9 | negative selection | 5350326 | 31201773 | 31201795 | 16 | - | 27760321 | MOLM13 | viability | ACAAACGTTGAGTGGCTGCTGG | PYCARD | ENSG00000103490 | -0.0653177324680091 | [816,720] | [690,177] | 0 | hSpCas9 | negative selection | 5433787 | 31201798 | 31201820 | 16 | + | 27760321 | MOLM13 | viability | CCTCGCGATAAGCGCAGCCCGG | PYCARD | ENSG00000103490 | 1.166062591240912 | [534,434] | [975,299] | 7 | hSpCas9 | negative selection | 5433788 | 31201816 | 31201838 | 16 | - | 27760321 | MOLM13 | viability | GCACTTTATAGACCAGCACCGG | PYCARD | ENSG00000103490 | 0.07654970985475783 | [472,423] | [299,237] | 0 | hSpCas9 | negative selection | 5433789 | 31201780 | 31201803 | 16 | - | 27260156 | BXPC3 | viability | CGAGGGTCACAAACGTTGAGTGG | PYCARD | ENSG00000103490 | 0.30638368815246764 | [201] | [229,244,205,379] | 6 | hSpCas9 | negative selection | 5565763 | 31201797 | 31201820 | 16 | + | 27260156 | BXPC3 | viability | CCCTCGCGATAAGCGCAGCCCGG | PYCARD | ENSG00000103490 | 0.30759881031507763 | [211] | [251,250,199,411] | 6 | hSpCas9 | negative selection | 5630019 | 31201780 | 31201803 | 16 | - | 27260156 | A673 | viability | CGAGGGTCACAAACGTTGAGTGG | PYCARD | ENSG00000103490 | 0.17458173795355814 | [201] | [368,200,269,266] | 4 | hSpCas9 | negative selection | 5687014 | 31201797 | 31201820 | 16 | + | 27260156 | A673 | viability | CCCTCGCGATAAGCGCAGCCCGG | PYCARD | ENSG00000103490 | 0.12168053121843658 | [211] | [236,152,370,347] | 3 | hSpCas9 | negative selection | 5751270 | 31201780 | 31201803 | 16 | - | 27260156 | A375 | viability | CGAGGGTCACAAACGTTGAGTGG | PYCARD | ENSG00000103490 | -0.3489229021743665 | [201] | [228,228,87,198] | -5 | hSpCas9 | negative selection | 5808265 | 31201797 | 31201820 | 16 | + | 27260156 | A375 | viability | CCCTCGCGATAAGCGCAGCCCGG | PYCARD | ENSG00000103490 | 0.4037952952787667 | [211] | [260,343,360,342] | 6 | hSpCas9 | negative selection | 5872521 | 31201780 | 31201803 | 16 | - | 27260156 | COLO741 | viability | CGAGGGTCACAAACGTTGAGTGG | PYCARD | ENSG00000103490 | 0.03913248117713719 | [201] | [291,278,228] | 0 | hSpCas9 | negative selection | 5929516 | 31201797 | 31201820 | 16 | + | 27260156 | COLO741 | viability | CCCTCGCGATAAGCGCAGCCCGG | PYCARD | ENSG00000103490 | 0.16220127005107576 | [211] | [337,290,283] | 3 | hSpCas9 | negative selection | 5993772 | 31201780 | 31201803 | 16 | - | 27260156 | CAL120 | viability | CGAGGGTCACAAACGTTGAGTGG | PYCARD | ENSG00000103490 | 0.5867527953324287 | [201] | [470,383,292] | 8 | hSpCas9 | negative selection | 6050767 | 31201797 | 31201820 | 16 | + | 27260156 | CAL120 | viability | CCCTCGCGATAAGCGCAGCCCGG | PYCARD | ENSG00000103490 | 0.37708481786047 | [211] | [265,341,406] | 5 | hSpCas9 | negative selection | 6115023 | 31201780 | 31201803 | 16 | - | 27260156 | CADOES1 | viability | CGAGGGTCACAAACGTTGAGTGG | PYCARD | ENSG00000103490 | 0.3646982045025373 | [201] | [215,286,191,273] | 6 | hSpCas9 | negative selection | 6172018 | 31201797 | 31201820 | 16 | + | 27260156 | CADOES1 | viability | CCCTCGCGATAAGCGCAGCCCGG | PYCARD | ENSG00000103490 | 0.5496713020509639 | [211] | [258,469,211,210] | 8 | hSpCas9 | negative selection | 6236274 | 31201780 | 31201803 | 16 | - | 27260156 | EWS502 | viability | CGAGGGTCACAAACGTTGAGTGG | PYCARD | ENSG00000103490 | -0.2023231629183393 | [201] | [101,215,199,237] | -4 | hSpCas9 | negative selection | 6293269 | 31201797 | 31201820 | 16 | + | 27260156 | EWS502 | viability | CCCTCGCGATAAGCGCAGCCCGG | PYCARD | ENSG00000103490 | 0.2510632441811329 | [211] | [320,243,257,236] | 4 | hSpCas9 | negative selection | 6357525 | 31201780 | 31201803 | 16 | - | 27260156 | EW8 | viability | CGAGGGTCACAAACGTTGAGTGG | PYCARD | ENSG00000103490 | -0.07269063266459042 | [201] | [201,259,114,57] | -1 | hSpCas9 | negative selection | 6414520 | 31201797 | 31201820 | 16 | + | 27260156 | EW8 | viability | CCCTCGCGATAAGCGCAGCCCGG | PYCARD | ENSG00000103490 | 0.3555875422546815 | [211] | [241,221,178,244] | 6 | hSpCas9 | negative selection | 6478776 | 31201780 | 31201803 | 16 | - | 27260156 | CORL105 | viability | CGAGGGTCACAAACGTTGAGTGG | PYCARD | ENSG00000103490 | -0.252941262019021 | [201] | [262,175,194,161] | -5 | hSpCas9 | negative selection | 6535771 | 31201797 | 31201820 | 16 | + | 27260156 | CORL105 | viability | CCCTCGCGATAAGCGCAGCCCGG | PYCARD | ENSG00000103490 | 0.030333342379327055 | [211] | [224,199,337,263] | 0 | hSpCas9 | negative selection | 6600027 | 31201780 | 31201803 | 16 | - | 27260156 | HS294T | viability | CGAGGGTCACAAACGTTGAGTGG | PYCARD | ENSG00000103490 | -0.13645738539313323 | [201] | [66,42,85,92] | -2 | hSpCas9 | negative selection | 6657022 | 31201797 | 31201820 | 16 | + | 27260156 | HS294T | viability | CCCTCGCGATAAGCGCAGCCCGG | PYCARD | ENSG00000103490 | 0.24292243818953962 | [211] | [66,133,67,124] | 3 | hSpCas9 | negative selection | 6721278 | 31201780 | 31201803 | 16 | - | 27260156 | HCC44 | viability | CGAGGGTCACAAACGTTGAGTGG | PYCARD | ENSG00000103490 | 0.22574083102021714 | [201] | [491,168,271,171] | 3 | hSpCas9 | negative selection | 6778273 | 31201797 | 31201820 | 16 | + | 27260156 | HCC44 | viability | CCCTCGCGATAAGCGCAGCCCGG | PYCARD | ENSG00000103490 | -0.05895769671480222 | [211] | [198,261,336,134] | -1 | hSpCas9 | negative selection | 6842529 | 31201780 | 31201803 | 16 | - | 27260156 | G402 | viability | CGAGGGTCACAAACGTTGAGTGG | PYCARD | ENSG00000103490 | 0.1415925752194096 | [201] | [127,505,186,258] | 1 | hSpCas9 | negative selection | 6899524 | 31201797 | 31201820 | 16 | + | 27260156 | G402 | viability | CCCTCGCGATAAGCGCAGCCCGG | PYCARD | ENSG00000103490 | 0.411345888454436 | [211] | [297,249,286,518] | 5 | hSpCas9 | negative selection | 6963780 | 31201780 | 31201803 | 16 | - | 27260156 | L33 | viability | CGAGGGTCACAAACGTTGAGTGG | PYCARD | ENSG00000103490 | 0.001228254673523832 | [201] | [276,59,97,226] | 0 | hSpCas9 | negative selection | 7020775 | 31201797 | 31201820 | 16 | + | 27260156 | L33 | viability | CCCTCGCGATAAGCGCAGCCCGG | PYCARD | ENSG00000103490 | 0.11556610088009722 | [211] | [323,68,131,213] | 2 | hSpCas9 | negative selection | 7085031 | 31201780 | 31201803 | 16 | - | 27260156 | K562 | viability | CGAGGGTCACAAACGTTGAGTGG | PYCARD | ENSG00000103490 | 0.24281848199382539 | [201] | [306,202,284,75] | 3 | hSpCas9 | negative selection | 7142026 | 31201797 | 31201820 | 16 | + | 27260156 | K562 | viability | CCCTCGCGATAAGCGCAGCCCGG | PYCARD | ENSG00000103490 | 0.12424455548416602 | [211] | [201,139,365,117] | 1 | hSpCas9 | negative selection | 7206282 | 31201780 | 31201803 | 16 | - | 27260156 | HT29 | viability | CGAGGGTCACAAACGTTGAGTGG | PYCARD | ENSG00000103490 | -0.026411376035606393 | [201] | [325,251,203,193] | 0 | hSpCas9 | negative selection | 7263277 | 31201797 | 31201820 | 16 | + | 27260156 | HT29 | viability | CCCTCGCGATAAGCGCAGCCCGG | PYCARD | ENSG00000103490 | 0.2258487746534189 | [211] | [307,361,335,213] | 4 | hSpCas9 | negative selection | 7327533 | 31201780 | 31201803 | 16 | - | 27260156 | MHHES1 | viability | CGAGGGTCACAAACGTTGAGTGG | PYCARD | ENSG00000103490 | 0.1239879708178826 | [201] | [242,285,262,206] | 2 | hSpCas9 | negative selection | 7384528 | 31201797 | 31201820 | 16 | + | 27260156 | MHHES1 | viability | CCCTCGCGATAAGCGCAGCCCGG | PYCARD | ENSG00000103490 | -0.13506351440857167 | [211] | [199,231,244,192] | -3 | hSpCas9 | negative selection | 7448784 | 31201780 | 31201803 | 16 | - | 27260156 | MEWO | viability | CGAGGGTCACAAACGTTGAGTGG | PYCARD | ENSG00000103490 | -0.26946658698863657 | [201] | [210,120,148] | -5 | hSpCas9 | negative selection | 7505779 | 31201797 | 31201820 | 16 | + | 27260156 | MEWO | viability | CCCTCGCGATAAGCGCAGCCCGG | PYCARD | ENSG00000103490 | 0.41051304269335576 | [211] | [310,261,226] | 8 | hSpCas9 | negative selection | 7570035 | 31201780 | 31201803 | 16 | - | 27260156 | LNCAPCLONEFGC | viability | CGAGGGTCACAAACGTTGAGTGG | PYCARD | ENSG00000103490 | 0.27337546031911586 | [201] | [328,211,200,137] | 4 | hSpCas9 | negative selection | 7627030 | 31201797 | 31201820 | 16 | + | 27260156 | LNCAPCLONEFGC | viability | CCCTCGCGATAAGCGCAGCCCGG | PYCARD | ENSG00000103490 | 0.567278769228027 | [211] | [230,218,537,192] | 8 | hSpCas9 | negative selection | 7691286 | 31201780 | 31201803 | 16 | - | 27260156 | PANC0327 | viability | CGAGGGTCACAAACGTTGAGTGG | PYCARD | ENSG00000103490 | 0.11031291932203535 | [201] | [167,152,265,190] | 1 | hSpCas9 | negative selection | 7748281 | 31201797 | 31201820 | 16 | + | 27260156 | PANC0327 | viability | CCCTCGCGATAAGCGCAGCCCGG | PYCARD | ENSG00000103490 | 0.22839617482382046 | [211] | [311,311,113,139] | 3 | hSpCas9 | negative selection | 7812537 | 31201780 | 31201803 | 16 | - | 27260156 | NCIH2009 | viability | CGAGGGTCACAAACGTTGAGTGG | PYCARD | ENSG00000103490 | 0.021360019068416003 | [201] | [245,331,271] | 0 | hSpCas9 | negative selection | 7869532 | 31201797 | 31201820 | 16 | + | 27260156 | NCIH2009 | viability | CCCTCGCGATAAGCGCAGCCCGG | PYCARD | ENSG00000103490 | -0.007835026208782958 | [211] | [295,159,429] | 0 | hSpCas9 | negative selection | 7933788 | 31201780 | 31201803 | 16 | - | 27260156 | NCIH1373 | viability | CGAGGGTCACAAACGTTGAGTGG | PYCARD | ENSG00000103490 | -0.03497325562324938 | [201] | [157,256,176,73] | 0 | hSpCas9 | negative selection | 7990783 | 31201797 | 31201820 | 16 | + | 27260156 | NCIH1373 | viability | CCCTCGCGATAAGCGCAGCCCGG | PYCARD | ENSG00000103490 | 0.49437406641596937 | [211] | [442,312,259,89] | 5 | hSpCas9 | negative selection | 8055039 | 31201780 | 31201803 | 16 | - | 27260156 | PATU8902 | viability | CGAGGGTCACAAACGTTGAGTGG | PYCARD | ENSG00000103490 | -0.3006711278467007 | [201] | [182,265,277,164] | -3 | hSpCas9 | negative selection | 8112034 | 31201797 | 31201820 | 16 | + | 27260156 | PATU8902 | viability | CCCTCGCGATAAGCGCAGCCCGG | PYCARD | ENSG00000103490 | 0.764337346807471 | [211] | [716,395,433,464] | 7 | hSpCas9 | negative selection | 8176290 | 31201780 | 31201803 | 16 | - | 27260156 | PANC1 | viability | CGAGGGTCACAAACGTTGAGTGG | PYCARD | ENSG00000103490 | 0.24528483685223357 | [201] | [133,363,209,153] | 4 | hSpCas9 | negative selection | 8233285 | 31201797 | 31201820 | 16 | + | 27260156 | PANC1 | viability | CCCTCGCGATAAGCGCAGCCCGG | PYCARD | ENSG00000103490 | -0.22839441295164842 | [211] | [170,223,119,122] | -4 | hSpCas9 | negative selection | 8297541 | 31201780 | 31201803 | 16 | - | 27260156 | PANC0813 | viability | CGAGGGTCACAAACGTTGAGTGG | PYCARD | ENSG00000103490 | 0.3668130453592381 | [201] | [336,371,180,333] | 6 | hSpCas9 | negative selection | 8354536 | 31201797 | 31201820 | 16 | + | 27260156 | PANC0813 | viability | CCCTCGCGATAAGCGCAGCCCGG | PYCARD | ENSG00000103490 | 0.1405357696545788 | [211] | [388,218,277,224] | 2 | hSpCas9 | negative selection | 8418792 | 31201780 | 31201803 | 16 | - | 27260156 | RDES | viability | CGAGGGTCACAAACGTTGAGTGG | PYCARD | ENSG00000103490 | -0.40983901943644896 | [201] | [134,156,189,231] | -6 | hSpCas9 | negative selection | 8475787 | 31201797 | 31201820 | 16 | + | 27260156 | RDES | viability | CCCTCGCGATAAGCGCAGCCCGG | PYCARD | ENSG00000103490 | 0.24867192081834333 | [211] | [252,369,276,240] | 4 | hSpCas9 | negative selection | 8540043 | 31201780 | 31201803 | 16 | - | 27260156 | PC3 | viability | CGAGGGTCACAAACGTTGAGTGG | PYCARD | ENSG00000103490 | -0.12398606579026739 | [201] | [127,192,396,104] | -3 | hSpCas9 | negative selection | 8597038 | 31201797 | 31201820 | 16 | + | 27260156 | PC3 | viability | CCCTCGCGATAAGCGCAGCCCGG | PYCARD | ENSG00000103490 | 0.7013809535052022 | [211] | [265,437,412,267] | 9 | hSpCas9 | negative selection | 8661294 | 31201780 | 31201803 | 16 | - | 27260156 | PATU8988T | viability | CGAGGGTCACAAACGTTGAGTGG | PYCARD | ENSG00000103490 | 0.06968173284078416 | [201] | [206,400,126,94] | 1 | hSpCas9 | negative selection | 8718289 | 31201797 | 31201820 | 16 | + | 27260156 | PATU8988T | viability | CCCTCGCGATAAGCGCAGCCCGG | PYCARD | ENSG00000103490 | 0.38426055243758583 | [211] | [299,317,172,285] | 6 | hSpCas9 | negative selection | 8782545 | 31201780 | 31201803 | 16 | - | 27260156 | T47D | viability | CGAGGGTCACAAACGTTGAGTGG | PYCARD | ENSG00000103490 | 0.25646534391648124 | [201] | [346,252,258,267] | 5 | hSpCas9 | negative selection | 8839540 | 31201797 | 31201820 | 16 | + | 27260156 | T47D | viability | CCCTCGCGATAAGCGCAGCCCGG | PYCARD | ENSG00000103490 | 0.1179634124529374 | [211] | [240,294,215,319] | 2 | hSpCas9 | negative selection | 8903796 | 31201780 | 31201803 | 16 | - | 27260156 | SU8686 | viability | CGAGGGTCACAAACGTTGAGTGG | PYCARD | ENSG00000103490 | 0.43622720151401484 | [201] | [171,241,322,378] | 7 | hSpCas9 | negative selection | 8960791 | 31201797 | 31201820 | 16 | + | 27260156 | SU8686 | viability | CCCTCGCGATAAGCGCAGCCCGG | PYCARD | ENSG00000103490 | 0.308363016817665 | [211] | [180,245,371,252] | 5 | hSpCas9 | negative selection | 9025047 | 31201780 | 31201803 | 16 | - | 27260156 | SKES1 | viability | CGAGGGTCACAAACGTTGAGTGG | PYCARD | ENSG00000103490 | 0.16528421777534774 | [201] | [137,361,229,180] | 3 | hSpCas9 | negative selection | 9082042 | 31201797 | 31201820 | 16 | + | 27260156 | SKES1 | viability | CCCTCGCGATAAGCGCAGCCCGG | PYCARD | ENSG00000103490 | 0.36971957534661404 | [211] | [238,400,262,205] | 7 | hSpCas9 | negative selection | 9146298 | 31201780 | 31201803 | 16 | - | 27260156 | TOV112D | viability | CGAGGGTCACAAACGTTGAGTGG | PYCARD | ENSG00000103490 | -0.2070802496857982 | [201] | [62,89,257,256] | -4 | hSpCas9 | negative selection | 9203293 | 31201797 | 31201820 | 16 | + | 27260156 | TOV112D | viability | CCCTCGCGATAAGCGCAGCCCGG | PYCARD | ENSG00000103490 | 0.18942553287274655 | [211] | [339,170,175,270] | 3 | hSpCas9 | negative selection | 9267549 | 31201780 | 31201803 | 16 | - | 27260156 | TC71 | viability | CGAGGGTCACAAACGTTGAGTGG | PYCARD | ENSG00000103490 | -0.04951006616409637 | [201] | [262,149,188,235] | -1 | hSpCas9 | negative selection | 9324544 | 31201797 | 31201820 | 16 | + | 27260156 | TC71 | viability | CCCTCGCGATAAGCGCAGCCCGG | PYCARD | ENSG00000103490 | 0.20953386524661732 | [211] | [248,202,264,338] | 5 | hSpCas9 | negative selection | 9388800 | 31201780 | 31201803 | 16 | - | 27260156 | TC32 | viability | CGAGGGTCACAAACGTTGAGTGG | PYCARD | ENSG00000103490 | 0.0038001381863288497 | [201] | [207,185,196,155] | 0 | hSpCas9 | negative selection | 9445795 | 31201797 | 31201820 | 16 | + | 27260156 | TC32 | viability | CCCTCGCGATAAGCGCAGCCCGG | PYCARD | ENSG00000103490 | 0.26131660778016863 | [211] | [297,89,259,352] | 4 | hSpCas9 | negative selection | 9510051 | 31201617 | 31201640 | 16 | + | 27869803 | HPAFII | viability after 27 days | ACTGGGACTCCCTTAGGGCCTGG | PYCARD | ENSG00000103490 | 1.497896179132458 | [140] | [234,187,NaN] | 9 | hSpCas9 | negative selection | 9556907 | 31201797 | 31201820 | 16 | - | 27869803 | HPAFII | viability after 27 days | CCGGGCTGCGCTTATCGCGAGGG | PYCARD | ENSG00000103490 | 0.12686298424024434 | [482] | [531,64,NaN] | 1 | hSpCas9 | negative selection | 9556908 | 31201617 | 31201640 | 16 | + | 27869803 | HPAFII | viability after 15 days | ACTGGGACTCCCTTAGGGCCTGG | PYCARD | ENSG00000103490 | 0.916684330056883 | [140] | [290,282,NaN] | 8 | hSpCas9 | negative selection | 9639356 | 31201797 | 31201820 | 16 | - | 27869803 | HPAFII | viability after 15 days | CCGGGCTGCGCTTATCGCGAGGG | PYCARD | ENSG00000103490 | -0.7082938725141698 | [482] | [580,153,NaN] | -6 | hSpCas9 | negative selection | 9639357 | 31201617 | 31201640 | 16 | + | 27869803 | ASPC1 | viability after 36 days | ACTGGGACTCCCTTAGGGCCTGG | PYCARD | ENSG00000103490 | -0.7639681157740389 | [411] | [59,104,84] | -6 | hSpCas9 | negative selection | 9721805 | 31201797 | 31201820 | 16 | - | 27869803 | ASPC1 | viability after 36 days | CCGGGCTGCGCTTATCGCGAGGG | PYCARD | ENSG00000103490 | -0.36785650156955896 | [1126] | [487,260,207] | -4 | hSpCas9 | negative selection | 9721806 | 31201617 | 31201640 | 16 | + | 27869803 | PATU8988S | viability after 35 days | ACTGGGACTCCCTTAGGGCCTGG | PYCARD | ENSG00000103490 | 0.24718996300044815 | [248] | [130,106,NaN] | 3 | hSpCas9 | negative selection | 9804254 | 31201797 | 31201820 | 16 | - | 27869803 | PATU8988S | viability after 35 days | CCGGGCTGCGCTTATCGCGAGGG | PYCARD | ENSG00000103490 | 0.24840467168805402 | [922] | [259,623,NaN] | 3 | hSpCas9 | negative selection | 9804255 | 31201617 | 31201640 | 16 | + | 27869803 | PATU8988S | viability after 31 days | ACTGGGACTCCCTTAGGGCCTGG | PYCARD | ENSG00000103490 | 0.2878676924483714 | [248] | [184,39,NaN] | 3 | hSpCas9 | negative selection | 9886703 | 31201797 | 31201820 | 16 | - | 27869803 | PATU8988S | viability after 31 days | CCGGGCTGCGCTTATCGCGAGGG | PYCARD | ENSG00000103490 | 0.28485423997878556 | [922] | [344,579,NaN] | 3 | hSpCas9 | negative selection | 9886704 | 31201617 | 31201640 | 16 | + | 27869803 | HPAFII | viability after 35 days | ACTGGGACTCCCTTAGGGCCTGG | PYCARD | ENSG00000103490 | 2.497229827042349 | [140] | [553,232,NaN] | 9 | hSpCas9 | negative selection | 9969152 | 31201797 | 31201820 | 16 | - | 27869803 | HPAFII | viability after 35 days | CCGGGCTGCGCTTATCGCGAGGG | PYCARD | ENSG00000103490 | 0.23103662335907316 | [482] | [492,54,NaN] | 1 | hSpCas9 | negative selection | 9969153 | 31201617 | 31201640 | 16 | + | 27869803 | HPAFII | viability after 31 days | ACTGGGACTCCCTTAGGGCCTGG | PYCARD | ENSG00000103490 | 2.0319194892283754 | [140] | [392,247,NaN] | 9 | hSpCas9 | negative selection | 10051601 | 31201797 | 31201820 | 16 | - | 27869803 | HPAFII | viability after 31 days | CCGGGCTGCGCTTATCGCGAGGG | PYCARD | ENSG00000103490 | 0.5976252579462432 | [482] | [726,64,NaN] | 4 | hSpCas9 | negative selection | 10051602 |