Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:260434
• Symbol:PYDC1
• Description:pyrin domain containing 1

DataSource: http://genomecrispr.dkfz.de/#!/results/PYDC1

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
31216998	31217021	16	-	26472758	Jiyoye	viability	GAAGCGCGAGGCCATCCTGAAGG	PYDC1	ENSG00000169900	0.8423140868412269	[195]	[264]	6	hSpCas9	negative selection	131746
31216818	31216841	16	-	26472758	Jiyoye	viability	CTACGCAGCCGAGCTCGTCGTGG	PYDC1	ENSG00000169900	-0.0078621177729703	[23]	[17]	0	hSpCas9	negative selection	131747
31216987	31217010	16	+	26472758	Jiyoye	viability	GTTCTCCAGCACCTTCAGGATGG	PYDC1	ENSG00000169900	-0.39605165492905425	[348]	[199]	-3	hSpCas9	negative selection	131748
31216974	31216997	16	-	26472758	Jiyoye	viability	GCTGGAGAACCTGACACCGGAGG	PYDC1	ENSG00000169900	0.41399664736188746	[210]	[211]	3	hSpCas9	negative selection	131749
31216941	31216964	16	-	26472758	Jiyoye	viability	GTTCAAGATGAAGCTGGGGACGG	PYDC1	ENSG00000169900	0.5440571879262603	[210]	[231]	4	hSpCas9	negative selection	131750
31216906	31216929	16	-	26472758	Jiyoye	viability	AGGGCTTTGAGCGCATCCCGCGG	PYDC1	ENSG00000169900	0.8126901066662106	[113]	[150]	6	hSpCas9	negative selection	131751
31216785	31216808	16	-	26472758	Jiyoye	viability	CGACATGCGCATGTTGGAGGAGG	PYDC1	ENSG00000169900	-0.20050719571536618	[95]	[62]	-1	hSpCas9	negative selection	131752
31216768	31216791	16	-	26472758	Jiyoye	viability	AGGAGGCCGCACGGCTGCAGCGG	PYDC1	ENSG00000169900	-1.3061112161908224	[140]	[42]	-7	hSpCas9	negative selection	131753
31217010	31217033	16	-	26472758	Jiyoye	viability	AGCCATGGGAACGAAGCGCGAGG	PYDC1	ENSG00000169900	2.7291034763932354	[0]	[4]	9	hSpCas9	negative selection	131754
31216878	31216901	16	-	26472758	Jiyoye	viability	GCTCGGGCAGCTAGATATCGTGG	PYDC1	ENSG00000169900	0.1441409756720795	[47]	[39]	1	hSpCas9	negative selection	131755
31216998	31217021	16	-	26472758	KBM7	viability	GAAGCGCGAGGCCATCCTGAAGG	PYDC1	ENSG00000169900	0.07453597642064791	[1501,1443]	[978,509]	0	hSpCas9	negative selection	322864
31216818	31216841	16	-	26472758	KBM7	viability	CTACGCAGCCGAGCTCGTCGTGG	PYDC1	ENSG00000169900	1.146394744021955	[68,146]	[133,101]	9	hSpCas9	negative selection	322865
31216987	31217010	16	+	26472758	KBM7	viability	GTTCTCCAGCACCTTCAGGATGG	PYDC1	ENSG00000169900	0.5961024018497703	[1112,845]	[701,678]	6	hSpCas9	negative selection	322866
31216974	31216997	16	-	26472758	KBM7	viability	GCTGGAGAACCTGACACCGGAGG	PYDC1	ENSG00000169900	-0.48746038161088634	[575,296]	[107,172]	-4	hSpCas9	negative selection	322867
31216941	31216964	16	-	26472758	KBM7	viability	GTTCAAGATGAAGCTGGGGACGG	PYDC1	ENSG00000169900	-0.23633956292282418	[696,505]	[343,141]	-2	hSpCas9	negative selection	322868
31216906	31216929	16	-	26472758	KBM7	viability	AGGGCTTTGAGCGCATCCCGCGG	PYDC1	ENSG00000169900	0.6166583510268571	[388,310]	[284,219]	6	hSpCas9	negative selection	322869
31216785	31216808	16	-	26472758	KBM7	viability	CGACATGCGCATGTTGGAGGAGG	PYDC1	ENSG00000169900	1.3398618584859299	[326,414]	[447,449]	9	hSpCas9	negative selection	322870
31216768	31216791	16	-	26472758	KBM7	viability	AGGAGGCCGCACGGCTGCAGCGG	PYDC1	ENSG00000169900	-0.2784793875075287	[336,389]	[120,161]	-3	hSpCas9	negative selection	322871
31217010	31217033	16	-	26472758	KBM7	viability	AGCCATGGGAACGAAGCGCGAGG	PYDC1	ENSG00000169900	1.9704514407378289	[84,0]	[48,91]	9	hSpCas9	negative selection	322872
31216878	31216901	16	-	26472758	KBM7	viability	GCTCGGGCAGCTAGATATCGTGG	PYDC1	ENSG00000169900	0.3813834861938148	[355,297]	[77,307]	4	hSpCas9	negative selection	322873
31216998	31217021	16	-	26472758	Raji	viability	GAAGCGCGAGGCCATCCTGAAGG	PYDC1	ENSG00000169900	0.43309610508847585	[532]	[166]	4	hSpCas9	negative selection	513982
31216818	31216841	16	-	26472758	Raji	viability	CTACGCAGCCGAGCTCGTCGTGG	PYDC1	ENSG00000169900	0.8685966757864827	[58]	[24]	7	hSpCas9	negative selection	513983
31216987	31217010	16	+	26472758	Raji	viability	GTTCTCCAGCACCTTCAGGATGG	PYDC1	ENSG00000169900	0.09165060910900313	[460]	[113]	0	hSpCas9	negative selection	513984
31216974	31216997	16	-	26472758	Raji	viability	GCTGGAGAACCTGACACCGGAGG	PYDC1	ENSG00000169900	0.5792070607440205	[273]	[94]	5	hSpCas9	negative selection	513985
31216941	31216964	16	-	26472758	Raji	viability	GTTCAAGATGAAGCTGGGGACGG	PYDC1	ENSG00000169900	-0.5376037364197743	[318]	[50]	-4	hSpCas9	negative selection	513986
31216906	31216929	16	-	26472758	Raji	viability	AGGGCTTTGAGCGCATCCCGCGG	PYDC1	ENSG00000169900	0.6004235466537164	[215]	[75]	5	hSpCas9	negative selection	513987
31216785	31216808	16	-	26472758	Raji	viability	CGACATGCGCATGTTGGAGGAGG	PYDC1	ENSG00000169900	0.5162688076708482	[234]	[77]	5	hSpCas9	negative selection	513988
31216768	31216791	16	-	26472758	Raji	viability	AGGAGGCCGCACGGCTGCAGCGG	PYDC1	ENSG00000169900	-1.0423635841310828	[283]	[31]	-6	hSpCas9	negative selection	513989
31217010	31217033	16	-	26472758	Raji	viability	AGCCATGGGAACGAAGCGCGAGG	PYDC1	ENSG00000169900	-0.647503966789869	[26]	[3]	-5	hSpCas9	negative selection	513990
31216878	31216901	16	-	26472758	Raji	viability	GCTCGGGCAGCTAGATATCGTGG	PYDC1	ENSG00000169900	-0.8255022687678634	[167]	[21]	-6	hSpCas9	negative selection	513991
31216998	31217021	16	-	26472758	K562	viability	GAAGCGCGAGGCCATCCTGAAGG	PYDC1	ENSG00000169900	0.7517406841833185	[737]	[1048]	6	hSpCas9	negative selection	705100
31216818	31216841	16	-	26472758	K562	viability	CTACGCAGCCGAGCTCGTCGTGG	PYDC1	ENSG00000169900	0.44605258883609733	[119]	[137]	3	hSpCas9	negative selection	705101
31216987	31217010	16	+	26472758	K562	viability	GTTCTCCAGCACCTTCAGGATGG	PYDC1	ENSG00000169900	0.7921870301231775	[811]	[1186]	6	hSpCas9	negative selection	705102
31216974	31216997	16	-	26472758	K562	viability	GCTGGAGAACCTGACACCGGAGG	PYDC1	ENSG00000169900	-0.45441173761298814	[335]	[206]	-3	hSpCas9	negative selection	705103
31216941	31216964	16	-	26472758	K562	viability	GTTCAAGATGAAGCTGGGGACGG	PYDC1	ENSG00000169900	-0.573066874671855	[392]	[222]	-4	hSpCas9	negative selection	705104
31216906	31216929	16	-	26472758	K562	viability	AGGGCTTTGAGCGCATCCCGCGG	PYDC1	ENSG00000169900	0.7372757603121769	[414]	[583]	6	hSpCas9	negative selection	705105
31216785	31216808	16	-	26472758	K562	viability	CGACATGCGCATGTTGGAGGAGG	PYDC1	ENSG00000169900	0.7289607372432442	[465]	[651]	6	hSpCas9	negative selection	705106
31216768	31216791	16	-	26472758	K562	viability	AGGAGGCCGCACGGCTGCAGCGG	PYDC1	ENSG00000169900	0.5173009194565878	[364]	[440]	4	hSpCas9	negative selection	705107
31217010	31217033	16	-	26472758	K562	viability	AGCCATGGGAACGAAGCGCGAGG	PYDC1	ENSG00000169900	0.8400284725871114	[44]	[67]	7	hSpCas9	negative selection	705108
31216878	31216901	16	-	26472758	K562	viability	GCTCGGGCAGCTAGATATCGTGG	PYDC1	ENSG00000169900	0.8909233733895827	[282]	[442]	7	hSpCas9	negative selection	705109
31216777	31216800	16	-	26627737	DLD1	viability	GCATGTTGGAGGAGGCCGCACGG	PYDC1	ENSG00000169900	-1.3872262291852482	[323]	[69,30,17]	-8	hSpCas9	negative selection	793899
31216905	31216928	16	-	26627737	DLD1	viability	GGGCTTTGAGCGCATCCCGCGGG	PYDC1	ENSG00000169900	0.6732949318374359	[229]	[85,171,91]	6	hSpCas9	negative selection	793900
31217008	31217031	16	+	26627737	DLD1	viability	GGCCTCGCGCTTCGTTCCCATGG	PYDC1	ENSG00000169900	0.8363901493080468	[190]	[148,4,153]	7	hSpCas9	negative selection	793901
31217010	31217033	16	-	26627737	DLD1	viability	AGCCATGGGAACGAAGCGCGAGG	PYDC1	ENSG00000169900	-1.461159687213641	[975]	[152,63,112]	-8	hSpCas9	negative selection	793902
31216777	31216800	16	-	26627737	GBM cells	viability after 5 days	GCATGTTGGAGGAGGCCGCACGG	PYDC1	ENSG00000169900	0.5985663105838359	[140]	[106,121]	8	hSpCas9	negative selection	876214
31216905	31216928	16	-	26627737	GBM cells	viability after 5 days	GGGCTTTGAGCGCATCCCGCGGG	PYDC1	ENSG00000169900	0.09531108768918894	[95]	[43,65]	1	hSpCas9	negative selection	876215
31217008	31217031	16	+	26627737	GBM cells	viability after 5 days	GGCCTCGCGCTTCGTTCCCATGG	PYDC1	ENSG00000169900	-0.5941261363944315	[75]	[31,21]	-7	hSpCas9	negative selection	876216
31217010	31217033	16	-	26627737	GBM cells	viability after 5 days	AGCCATGGGAACGAAGCGCGAGG	PYDC1	ENSG00000169900	0.5684406708653146	[126]	[75,125]	7	hSpCas9	negative selection	876217
31216777	31216800	16	-	26627737	GBM cells	viability after 13 days	GCATGTTGGAGGAGGCCGCACGG	PYDC1	ENSG00000169900	0.7448704182833118	[140]	[125,129]	8	hSpCas9	negative selection	958529
31216905	31216928	16	-	26627737	GBM cells	viability after 13 days	GGGCTTTGAGCGCATCCCGCGGG	PYDC1	ENSG00000169900	0.27862396125573574	[95]	[12,103]	3	hSpCas9	negative selection	958530
31217008	31217031	16	+	26627737	GBM cells	viability after 13 days	GGCCTCGCGCTTCGTTCCCATGG	PYDC1	ENSG00000169900	-0.06607765039583802	[75]	[61,20]	-1	hSpCas9	negative selection	958531
31217010	31217033	16	-	26627737	GBM cells	viability after 13 days	AGCCATGGGAACGAAGCGCGAGG	PYDC1	ENSG00000169900	0.3569428100774621	[126]	[106,72]	4	hSpCas9	negative selection	958532
31216777	31216800	16	-	26627737	GBM cells	viability after 21 days	GCATGTTGGAGGAGGCCGCACGG	PYDC1	ENSG00000169900	1.0159787631720427	[140]	[156,152]	8	hSpCas9	negative selection	1040844
31216905	31216928	16	-	26627737	GBM cells	viability after 21 days	GGGCTTTGAGCGCATCCCGCGGG	PYDC1	ENSG00000169900	0.5497220702661326	[95]	[79,72]	5	hSpCas9	negative selection	1040845
31217008	31217031	16	+	26627737	GBM cells	viability after 21 days	GGCCTCGCGCTTCGTTCCCATGG	PYDC1	ENSG00000169900	-0.4459193811334292	[75]	[22,36]	-4	hSpCas9	negative selection	1040846
31217010	31217033	16	-	26627737	GBM cells	viability after 21 days	AGCCATGGGAACGAAGCGCGAGG	PYDC1	ENSG00000169900	0.6830733057993762	[126]	[115,105]	7	hSpCas9	negative selection	1040847
31216777	31216800	16	-	26627737	RPE1	viability after 9 days	GCATGTTGGAGGAGGCCGCACGG	PYDC1	ENSG00000169900	8.938401560338251	[0]	[167,134]	9	hSpCas9	negative selection	1123159
31216905	31216928	16	-	26627737	RPE1	viability after 9 days	GGGCTTTGAGCGCATCCCGCGGG	PYDC1	ENSG00000169900	6.534653190336334	[3]	[102,132]	9	hSpCas9	negative selection	1123160
31217008	31217031	16	+	26627737	RPE1	viability after 9 days	GGCCTCGCGCTTCGTTCCCATGG	PYDC1	ENSG00000169900	0.6075277178435559	[165]	[45,121]	4	hSpCas9	negative selection	1123161
31217010	31217033	16	-	26627737	RPE1	viability after 9 days	AGCCATGGGAACGAAGCGCGAGG	PYDC1	ENSG00000169900	-0.14426118513351688	[806]	[218,240]	-1	hSpCas9	negative selection	1123162
31216777	31216800	16	-	26627737	RPE1	viability after 12 days	GCATGTTGGAGGAGGCCGCACGG	PYDC1	ENSG00000169900	9.097465219451461	[0]	[169,122]	9	hSpCas9	negative selection	1205474
31216905	31216928	16	-	26627737	RPE1	viability after 12 days	GGGCTTTGAGCGCATCCCGCGGG	PYDC1	ENSG00000169900	6.72900142583788	[3]	[96,131]	9	hSpCas9	negative selection	1205475
31217008	31217031	16	+	26627737	RPE1	viability after 12 days	GGCCTCGCGCTTCGTTCCCATGG	PYDC1	ENSG00000169900	-0.6280714589795964	[165]	[23,33]	-4	hSpCas9	negative selection	1205476
31217010	31217033	16	-	26627737	RPE1	viability after 12 days	AGCCATGGGAACGAAGCGCGAGG	PYDC1	ENSG00000169900	-0.9394051185769082	[806]	[80,146]	-6	hSpCas9	negative selection	1205477
31216777	31216800	16	-	26627737	RPE1	viability after 15 days	GCATGTTGGAGGAGGCCGCACGG	PYDC1	ENSG00000169900	7.766543733552288	[0]	[27,93]	9	hSpCas9	negative selection	1287789
31216905	31216928	16	-	26627737	RPE1	viability after 15 days	GGGCTTTGAGCGCATCCCGCGGG	PYDC1	ENSG00000169900	6.829683055414112	[3]	[88,166]	9	hSpCas9	negative selection	1287790
31217008	31217031	16	+	26627737	RPE1	viability after 15 days	GGCCTCGCGCTTCGTTCCCATGG	PYDC1	ENSG00000169900	1.2107854445347264	[165]	[97,118]	7	hSpCas9	negative selection	1287791
31217010	31217033	16	-	26627737	RPE1	viability after 15 days	AGCCATGGGAACGAAGCGCGAGG	PYDC1	ENSG00000169900	-0.2567004141489691	[806]	[186,194]	-2	hSpCas9	negative selection	1287792
31216777	31216800	16	-	26627737	RPE1	viability after 18 days	GCATGTTGGAGGAGGCCGCACGG	PYDC1	ENSG00000169900	8.958866653390446	[0]	[200,62]	9	hSpCas9	negative selection	1370104
31216905	31216928	16	-	26627737	RPE1	viability after 18 days	GGGCTTTGAGCGCATCCCGCGGG	PYDC1	ENSG00000169900	6.825775852950416	[3]	[91,154]	9	hSpCas9	negative selection	1370105
31217008	31217031	16	+	26627737	RPE1	viability after 18 days	GGCCTCGCGCTTCGTTCCCATGG	PYDC1	ENSG00000169900	1.3181937781841624	[165]	[73,151]	7	hSpCas9	negative selection	1370106
31217010	31217033	16	-	26627737	RPE1	viability after 18 days	AGCCATGGGAACGAAGCGCGAGG	PYDC1	ENSG00000169900	0.1415008281953866	[806]	[275,201]	0	hSpCas9	negative selection	1370107
31216777	31216800	16	-	26627737	HeLa	viability after 8 days	GCATGTTGGAGGAGGCCGCACGG	PYDC1	ENSG00000169900	1.2468748892657195	[224]	[124,279,265]	8	hSpCas9	negative selection	1452419
31216905	31216928	16	-	26627737	HeLa	viability after 8 days	GGGCTTTGAGCGCATCCCGCGGG	PYDC1	ENSG00000169900	0.24483237132401064	[296]	[270,55,157]	2	hSpCas9	negative selection	1452420
31217008	31217031	16	+	26627737	HeLa	viability after 8 days	GGCCTCGCGCTTCGTTCCCATGG	PYDC1	ENSG00000169900	0.7283039963317377	[88]	[176,15,26]	6	hSpCas9	negative selection	1452421
31217010	31217033	16	-	26627737	HeLa	viability after 8 days	AGCCATGGGAACGAAGCGCGAGG	PYDC1	ENSG00000169900	-0.01580349125326108	[288]	[61,151,143]	0	hSpCas9	negative selection	1452422
31216777	31216800	16	-	26627737	HeLa	viability after 12 days	GCATGTTGGAGGAGGCCGCACGG	PYDC1	ENSG00000169900	0.18950194372478602	[224]	[12,90,212]	1	hSpCas9	negative selection	1534734
31216905	31216928	16	-	26627737	HeLa	viability after 12 days	GGGCTTTGAGCGCATCCCGCGGG	PYDC1	ENSG00000169900	-0.2661251312706509	[296]	[55,128,116]	-2	hSpCas9	negative selection	1534735
31217008	31217031	16	+	26627737	HeLa	viability after 12 days	GGCCTCGCGCTTCGTTCCCATGG	PYDC1	ENSG00000169900	1.885189453585688	[88]	[192,43,181]	9	hSpCas9	negative selection	1534736
31217010	31217033	16	-	26627737	HeLa	viability after 12 days	AGCCATGGGAACGAAGCGCGAGG	PYDC1	ENSG00000169900	-0.6446980218837479	[288]	[153,4,79]	-5	hSpCas9	negative selection	1534737
31216777	31216800	16	-	26627737	HeLa	viability after 15 days	GCATGTTGGAGGAGGCCGCACGG	PYDC1	ENSG00000169900	1.0817264168779563	[224]	[219,194,163]	7	hSpCas9	negative selection	1617049
31216905	31216928	16	-	26627737	HeLa	viability after 15 days	GGGCTTTGAGCGCATCCCGCGGG	PYDC1	ENSG00000169900	-0.06050278070457199	[296]	[115,137,91]	0	hSpCas9	negative selection	1617050
31217008	31217031	16	+	26627737	HeLa	viability after 15 days	GGCCTCGCGCTTCGTTCCCATGG	PYDC1	ENSG00000169900	1.8915434242921225	[88]	[201,46,154]	9	hSpCas9	negative selection	1617051
31217010	31217033	16	-	26627737	HeLa	viability after 15 days	AGCCATGGGAACGAAGCGCGAGG	PYDC1	ENSG00000169900	0.7234671235226149	[288]	[104,295,181]	6	hSpCas9	negative selection	1617052
31216777	31216800	16	-	26627737	HeLa	viability after 18 days	GCATGTTGGAGGAGGCCGCACGG	PYDC1	ENSG00000169900	1.0570911748534322	[224]	[143,157,163]	7	hSpCas9	negative selection	1699364
31216905	31216928	16	-	26627737	HeLa	viability after 18 days	GGGCTTTGAGCGCATCCCGCGGG	PYDC1	ENSG00000169900	-0.04299399214952182	[296]	[79,114,91]	0	hSpCas9	negative selection	1699365
31217008	31217031	16	+	26627737	HeLa	viability after 18 days	GGCCTCGCGCTTCGTTCCCATGG	PYDC1	ENSG00000169900	1.8767411367894125	[88]	[131,39,154]	9	hSpCas9	negative selection	1699366
31217010	31217033	16	-	26627737	HeLa	viability after 18 days	AGCCATGGGAACGAAGCGCGAGG	PYDC1	ENSG00000169900	0.6998786072051875	[288]	[65,242,181]	5	hSpCas9	negative selection	1699367
31216777	31216800	16	-	26627737	HCT116	viability after 6 days	GCATGTTGGAGGAGGCCGCACGG	PYDC1	ENSG00000169900	-0.2927783416174744	[357]	[121,3]	-2	hSpCas9	negative selection	1781679
31216905	31216928	16	-	26627737	HCT116	viability after 6 days	GGGCTTTGAGCGCATCCCGCGGG	PYDC1	ENSG00000169900	0.6601038002770839	[208]	[136,4]	3	hSpCas9	negative selection	1781680
31217008	31217031	16	+	26627737	HCT116	viability after 6 days	GGCCTCGCGCTTCGTTCCCATGG	PYDC1	ENSG00000169900	0.264481617820441	[173]	[86,2]	1	hSpCas9	negative selection	1781681
31217010	31217033	16	-	26627737	HCT116	viability after 6 days	AGCCATGGGAACGAAGCGCGAGG	PYDC1	ENSG00000169900	-0.9100327643817971	[330]	[8,37]	-5	hSpCas9	negative selection	1781682
31216777	31216800	16	-	26627737	HCT116	viability after 8 days	GCATGTTGGAGGAGGCCGCACGG	PYDC1	ENSG00000169900	-0.8763885201883013	[226]	[62,46,93]	-8	hSpCas9	negative selection	1863994
31216905	31216928	16	-	26627737	HCT116	viability after 8 days	GGGCTTTGAGCGCATCCCGCGGG	PYDC1	ENSG00000169900	0.4463134856665702	[172]	[149,107,131]	4	hSpCas9	negative selection	1863995
31217008	31217031	16	+	26627737	HCT116	viability after 8 days	GGCCTCGCGCTTCGTTCCCATGG	PYDC1	ENSG00000169900	-0.2254526007158213	[117]	[52,74,38]	-3	hSpCas9	negative selection	1863996
31217010	31217033	16	-	26627737	HCT116	viability after 8 days	AGCCATGGGAACGAAGCGCGAGG	PYDC1	ENSG00000169900	1.0398303036711325	[193]	[220,187,249]	8	hSpCas9	negative selection	1863997
31216777	31216800	16	-	26627737	HCT116	viability after 9 days	GCATGTTGGAGGAGGCCGCACGG	PYDC1	ENSG00000169900	-0.4955742581930126	[357]	[83,54]	-4	hSpCas9	negative selection	1946309
31216905	31216928	16	-	26627737	HCT116	viability after 9 days	GGGCTTTGAGCGCATCCCGCGGG	PYDC1	ENSG00000169900	-2.850270865939057	[208]	[14,1]	-9	hSpCas9	negative selection	1946310
31217008	31217031	16	+	26627737	HCT116	viability after 9 days	GGCCTCGCGCTTCGTTCCCATGG	PYDC1	ENSG00000169900	1.0265563183093485	[173]	[97,91]	7	hSpCas9	negative selection	1946311
31217010	31217033	16	-	26627737	HCT116	viability after 9 days	AGCCATGGGAACGAAGCGCGAGG	PYDC1	ENSG00000169900	0.789224609948078	[330]	[159,146]	5	hSpCas9	negative selection	1946312
31216777	31216800	16	-	26627737	HCT116	viability after 12 days	GCATGTTGGAGGAGGCCGCACGG	PYDC1	ENSG00000169900	-0.2769189244778501	[226]	[100,91,101]	-3	hSpCas9	negative selection	2028624
31216905	31216928	16	-	26627737	HCT116	viability after 12 days	GGGCTTTGAGCGCATCCCGCGGG	PYDC1	ENSG00000169900	-0.016970830010420768	[172]	[72,46,149]	0	hSpCas9	negative selection	2028625
31217008	31217031	16	+	26627737	HCT116	viability after 12 days	GGCCTCGCGCTTCGTTCCCATGG	PYDC1	ENSG00000169900	0.4523322891217014	[117]	[127,94,27]	4	hSpCas9	negative selection	2028626
31217010	31217033	16	-	26627737	HCT116	viability after 12 days	AGCCATGGGAACGAAGCGCGAGG	PYDC1	ENSG00000169900	0.7775020051138002	[193]	[275,75,160]	7	hSpCas9	negative selection	2028627
31216777	31216800	16	-	26627737	HCT116	viability after 15 days	GCATGTTGGAGGAGGCCGCACGG	PYDC1	ENSG00000169900	0.7508739167421801	[226]	[75,121,439]	6	hSpCas9	negative selection	2110939
31216905	31216928	16	-	26627737	HCT116	viability after 15 days	GGGCTTTGAGCGCATCCCGCGGG	PYDC1	ENSG00000169900	0.07917154804570425	[172]	[149,118,51]	0	hSpCas9	negative selection	2110940
31217008	31217031	16	+	26627737	HCT116	viability after 15 days	GGCCTCGCGCTTCGTTCCCATGG	PYDC1	ENSG00000169900	0.6771781311043842	[117]	[119,139,66]	6	hSpCas9	negative selection	2110941
31217010	31217033	16	-	26627737	HCT116	viability after 15 days	AGCCATGGGAACGAAGCGCGAGG	PYDC1	ENSG00000169900	0.6418857400771063	[193]	[238,160,129]	6	hSpCas9	negative selection	2110942
31216777	31216800	16	-	26627737	HCT116	viability after 18 days	GCATGTTGGAGGAGGCCGCACGG	PYDC1	ENSG00000169900	0.8880639968155617	[226]	[88,106,429]	7	hSpCas9	negative selection	2193254
31216905	31216928	16	-	26627737	HCT116	viability after 18 days	GGGCTTTGAGCGCATCCCGCGGG	PYDC1	ENSG00000169900	-0.4542285326166451	[172]	[36,54,92]	-4	hSpCas9	negative selection	2193255
31217008	31217031	16	+	26627737	HCT116	viability after 18 days	GGCCTCGCGCTTCGTTCCCATGG	PYDC1	ENSG00000169900	0.19480303262389853	[117]	[46,28,124]	1	hSpCas9	negative selection	2193256
31217010	31217033	16	-	26627737	HCT116	viability after 18 days	AGCCATGGGAACGAAGCGCGAGG	PYDC1	ENSG00000169900	1.2846746778019877	[193]	[413,147,123]	8	hSpCas9	negative selection	2193257
31216916	31216939	16	+	24336569	HL60	viability	CGCTCAAAGCCCTCGCGCAGCGG	PYDC1	ENSG00000169900	-0.06743454072483812	[306]	[619]	0	hSpCas9	negative selection	2287777
31216925	31216948	16	-	24336569	HL60	viability	GGGACGGTGCCGCTGCGCGAGGG	PYDC1	ENSG00000169900	0.06673742265629745	[683]	[1515]	0	hSpCas9	negative selection	2287778
31216946	31216969	16	-	24336569	HL60	viability	AAGAAGTTCAAGATGAAGCTGGG	PYDC1	ENSG00000169900	0.8231070490766639	[1327]	[4971]	6	hSpCas9	negative selection	2287779
31216958	31216981	16	+	24336569	HL60	viability	TTGAACTTCTTGAGCTCCTCCGG	PYDC1	ENSG00000169900	0.5199865228808291	[86]	[263]	4	hSpCas9	negative selection	2287780
31216965	31216988	16	+	24336569	HL60	viability	TCTTGAGCTCCTCCGGTGTCAGG	PYDC1	ENSG00000169900	0.3132056009559857	[641]	[1687]	3	hSpCas9	negative selection	2287781
31216974	31216997	16	-	24336569	HL60	viability	GCTGGAGAACCTGACACCGGAGG	PYDC1	ENSG00000169900	-2.3201486450469417	[563]	[238]	-9	hSpCas9	negative selection	2287782
31216983	31217006	16	+	24336569	HL60	viability	TCAGGTTCTCCAGCACCTTCAGG	PYDC1	ENSG00000169900	-0.1270125739708912	[546]	[1059]	-1	hSpCas9	negative selection	2287783
31216992	31217015	16	-	24336569	HL60	viability	CGAGGCCATCCTGAAGGTGCTGG	PYDC1	ENSG00000169900	0.1458202802556956	[714]	[1673]	1	hSpCas9	negative selection	2287784
31216998	31217021	16	-	24336569	HL60	viability	GAAGCGCGAGGCCATCCTGAAGG	PYDC1	ENSG00000169900	0.4457829022359724	[713]	[2057]	4	hSpCas9	negative selection	2287785
31217008	31217031	16	+	24336569	HL60	viability	GGCCTCGCGCTTCGTTCCCATGG	PYDC1	ENSG00000169900	0.21199733895640552	[562]	[1379]	2	hSpCas9	negative selection	2287786
31216916	31216939	16	+	24336569	KBM7	viability	CGCTCAAAGCCCTCGCGCAGCGG	PYDC1	ENSG00000169900	0.42088181256578316	[174]	[638]	4	hSpCas9	negative selection	2354954
31216925	31216948	16	-	24336569	KBM7	viability	GGGACGGTGCCGCTGCGCGAGGG	PYDC1	ENSG00000169900	-0.22964504526491136	[462]	[1076]	-2	hSpCas9	negative selection	2354955
31216946	31216969	16	-	24336569	KBM7	viability	AAGAAGTTCAAGATGAAGCTGGG	PYDC1	ENSG00000169900	0.19908400384444636	[1334]	[4179]	1	hSpCas9	negative selection	2354956
31216958	31216981	16	+	24336569	KBM7	viability	TTGAACTTCTTGAGCTCCTCCGG	PYDC1	ENSG00000169900	1.0909903986878224	[78]	[458]	8	hSpCas9	negative selection	2354957
31216965	31216988	16	+	24336569	KBM7	viability	TCTTGAGCTCCTCCGGTGTCAGG	PYDC1	ENSG00000169900	0.9355490547752173	[419]	[2190]	7	hSpCas9	negative selection	2354958
31216974	31216997	16	-	24336569	KBM7	viability	GCTGGAGAACCTGACACCGGAGG	PYDC1	ENSG00000169900	-0.9526954852850772	[390]	[550]	-6	hSpCas9	negative selection	2354959
31216983	31217006	16	+	24336569	KBM7	viability	TCAGGTTCTCCAGCACCTTCAGG	PYDC1	ENSG00000169900	0.22169959010574888	[431]	[1373]	2	hSpCas9	negative selection	2354960
31216992	31217015	16	-	24336569	KBM7	viability	CGAGGCCATCCTGAAGGTGCTGG	PYDC1	ENSG00000169900	0.7900506640318199	[591]	[2791]	7	hSpCas9	negative selection	2354961
31216998	31217021	16	-	24336569	KBM7	viability	GAAGCGCGAGGCCATCCTGAAGG	PYDC1	ENSG00000169900	-0.17873411323472455	[763]	[1840]	-1	hSpCas9	negative selection	2354962
31217008	31217031	16	+	24336569	KBM7	viability	GGCCTCGCGCTTCGTTCCCATGG	PYDC1	ENSG00000169900	0.5092113514180783	[465]	[1808]	5	hSpCas9	negative selection	2354963
31217181	31217204	16	+	25494202	A375	resistance to PLX-4720 (puromycin)	ACTCTGCAAACACCGCCTAGAGG	PYDC1	ENSG00000169900	2.272707847997128	[235,1129]	[205,1306]	7	dCas9-VP64	positive selection	2467819
31217148	31217171	16	-	25494202	A375	resistance to PLX-4720 (puromycin)	CAGGAGCCACAGGGTTGAATAGG	PYDC1	ENSG00000169900	1.9081375950467658	[79,274]	[32,272]	6	dCas9-VP64	positive selection	2467820
31217230	31217253	16	+	25494202	A375	resistance to PLX-4720 (puromycin)	GGGGCGCCAAATTGTTGAGGTGG	PYDC1	ENSG00000169900	3.2020259560099404	[0,21]	[36,9]	8	dCas9-VP64	positive selection	2467821
31217181	31217204	16	+	25494202	A375	resistance to PLX-4720 (zeocin)	ACTCTGCAAACACCGCCTAGAGG	PYDC1	ENSG00000169900	-0.4058828955570546	[283,63]	[57,28]	-4	dCas9-VP64	positive selection	2563074
31217148	31217171	16	-	25494202	A375	resistance to PLX-4720 (zeocin)	CAGGAGCCACAGGGTTGAATAGG	PYDC1	ENSG00000169900	2.7118646193619744	[62,135]	[353,79]	9	dCas9-VP64	positive selection	2563075
31217230	31217253	16	+	25494202	A375	resistance to PLX-4720 (zeocin)	GGGGCGCCAAATTGTTGAGGTGG	PYDC1	ENSG00000169900	-0.8158491165034152	[120,36]	[13,14]	-7	dCas9-VP64	positive selection	2563076
31216890	31216913	16	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	AGCTGCCCGAGCGCGCCCCGCGG	PYDC1	ENSG00000169900	0.3874285918906688	[3,3]	[3,4]	7	hSpCas9	positive selection	3014973
31216904	31216927	16	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GGCTTTGAGCGCATCCCGCGGGG	PYDC1	ENSG00000169900	0.5497438489764472	[3,3]	[3,5]	9	hSpCas9	positive selection	3014974
31216925	31216948	16	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GGGACGGTGCCGCTGCGCGAGGG	PYDC1	ENSG00000169900	-0.286830125765566	[2,3]	[2,1]	-4	hSpCas9	positive selection	3014975
31216977	31217000	16	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GGTGCTGGAGAACCTGACACCGG	PYDC1	ENSG00000169900	0.6294365489333363	[3,3]	[3,6]	9	hSpCas9	positive selection	3014976
31216890	31216913	16	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	AGCTGCCCGAGCGCGCCCCGCGG	PYDC1	ENSG00000169900	0.16361202646187756	[3,3]	[3,1]	3	hSpCas9	positive selection	3082831
31216904	31216927	16	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GGCTTTGAGCGCATCCCGCGGGG	PYDC1	ENSG00000169900	-0.29391191515919035	[3,3]	[1,1]	-4	hSpCas9	positive selection	3082832
31216925	31216948	16	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GGGACGGTGCCGCTGCGCGAGGG	PYDC1	ENSG00000169900	0.1282327753992617	[2,2]	[2,1]	2	hSpCas9	positive selection	3082833
31216977	31217000	16	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GGTGCTGGAGAACCTGACACCGG	PYDC1	ENSG00000169900	-0.027156479321490734	[3,3]	[3,1]	0	hSpCas9	positive selection	3082834
31216878	31216901		-	24336571	A375	resistance to PLX after 7 days	GCTCGGGCAGCTAGATATCGTGG	PYDC1	ENSG00000169900	-0.10037092394758271	[10,11]	[10,9]	-3	hSpCas9	positive selection	3139098
31216831	31216854		+	24336571	A375	resistance to PLX after 7 days	GGCTGCGTAGTCCTCGTAGTAGG	PYDC1	ENSG00000169900	-0.11968863851164069	[17,20]	[17,17]	-4	hSpCas9	positive selection	3139099
31216878	31216901		-	24336571	A375	resistance to PLX after 14 days	GCTCGGGCAGCTAGATATCGTGG	PYDC1	ENSG00000169900	-0.22006745313034015	[8,8]	[3,2]	-2	hSpCas9	positive selection	3196891
31216831	31216854		+	24336571	A375	resistance to PLX after 14 days	GGCTGCGTAGTCCTCGTAGTAGG	PYDC1	ENSG00000169900	-0.4561796804237064	[17,19]	[7,4]	-5	hSpCas9	positive selection	3196892
31216878	31216901		-	24336571	A375	viability after 7 days	GCTCGGGCAGCTAGATATCGTGG	PYDC1	ENSG00000169900	0.17522219651422402	[10]	[10,11]	2	hSpCas9	negative selection	3254684
31216831	31216854		+	24336571	A375	viability after 7 days	GGCTGCGTAGTCCTCGTAGTAGG	PYDC1	ENSG00000169900	0.3374422383403554	[15]	[17,20]	5	hSpCas9	negative selection	3254685
31216878	31216901		-	24336571	A375	viability after 14 days	GCTCGGGCAGCTAGATATCGTGG	PYDC1	ENSG00000169900	-0.14159025178642903	[10]	[8,8]	-2	hSpCas9	negative selection	3312477
31216831	31216854		+	24336571	A375	viability after 14 days	GGCTGCGTAGTCCTCGTAGTAGG	PYDC1	ENSG00000169900	0.31622288754726885	[15]	[17,19]	4	hSpCas9	negative selection	3312478
31216878	31216901	16	-	27383988	293T	resistance to West Nile virus (flavivirus)	GCTCGGGCAGCTAGATATCGTGG	PYDC1	ENSG00000169900	1.6134700216711104	[49,49]	[0,0]	6	hSpCas9	positive selection	3388466
31217008	31217031	16	+	27383988	293T	resistance to West Nile virus (flavivirus)	GGCCTCGCGCTTCGTTCCCATGG	PYDC1	ENSG00000169900	0.5158592250446882	[106,106]	[0,0]	2	hSpCas9	positive selection	3388467
31216818	31216841	16	-	27383988	293T	resistance to West Nile virus (flavivirus)	CTACGCAGCCGAGCTCGTCGTGG	PYDC1	ENSG00000169900	-0.2662357446111776	[183,183]	[0,0]	-2	hSpCas9	positive selection	3388468
31216889	31216912	16	+	26780180	HT29	viability (Avana library 4 designs)	AGCTGCCCGAGCGCGCCCCGCGG	PYDC1	ENSG00000169900	0.311931926182003	[]	[]	1	hSpCas9	negative selection	3453223
31216904	31216927	16	-	26780180	HT29	viability (Avana library 4 designs)	GGCTTTGAGCGCATCCCGCGGGG	PYDC1	ENSG00000169900	0.0658671679333436	[]	[]	0	hSpCas9	negative selection	3453224
31216925	31216948	16	-	26780180	HT29	viability (Avana library 4 designs)	GGGACGGTGCCGCTGCGCGAGGG	PYDC1	ENSG00000169900	1.94155145896873	[]	[]	7	hSpCas9	negative selection	3453225
31216977	31217000	16	-	26780180	HT29	viability (Avana library 4 designs)	GGTGCTGGAGAACCTGACACCGG	PYDC1	ENSG00000169900	1.83283825237868	[]	[]	7	hSpCas9	negative selection	3453226
31216925	31216948	16	-	26780180	A375	viability (Avana lentiCRISPRv2)	GGGACGGTGCCGCTGCGCGAGGG	PYDC1	ENSG00000169900	3.14992642456138	[]	[]	5	hSpCas9	negative selection	3549978
31216977	31217000	16	-	26780180	A375	viability (Avana lentiCRISPRv2)	GGTGCTGGAGAACCTGACACCGG	PYDC1	ENSG00000169900	1.06272916593416	[]	[]	1	hSpCas9	negative selection	3549979
31216904	31216927	16	-	26780180	A375	viability (Avana lentiCRISPRv2)	GGCTTTGAGCGCATCCCGCGGGG	PYDC1	ENSG00000169900	6.03869812336344	[]	[]	9	hSpCas9	negative selection	3549980
31216889	31216912	16	+	26780180	A375	viability (Avana lentiCRISPRv2)	AGCTGCCCGAGCGCGCCCCGCGG	PYDC1	ENSG00000169900	6.65231931659313	[]	[]	9	hSpCas9	negative selection	3549981
31216941	31216964	16	-	26780180	A375	viability (Avana lentiCRISPRv2)	GTTCAAGATGAAGCTGGGGACGG	PYDC1	ENSG00000169900	2.99144289479625	[]	[]	4	hSpCas9	negative selection	3549982
31216987	31217010	16	+	26780180	A375	viability (Avana lentiCRISPRv2)	GTTCTCCAGCACCTTCAGGATGG	PYDC1	ENSG00000169900	-6.11032533121324	[]	[]	-6	hSpCas9	negative selection	3549983
31216925	31216948	16	-	26780180	A375	viability (Avana lentiGuide)	GGGACGGTGCCGCTGCGCGAGGG	PYDC1	ENSG00000169900	7.4986338820981	[]	[]	6	hSpCas9	negative selection	3658637
31216977	31217000	16	-	26780180	A375	viability (Avana lentiGuide)	GGTGCTGGAGAACCTGACACCGG	PYDC1	ENSG00000169900	6.20429605919598	[]	[]	5	hSpCas9	negative selection	3658638
31216904	31216927	16	-	26780180	A375	viability (Avana lentiGuide)	GGCTTTGAGCGCATCCCGCGGGG	PYDC1	ENSG00000169900	-1.30296295194669	[]	[]	-2	hSpCas9	negative selection	3658639
31216889	31216912	16	+	26780180	A375	viability (Avana lentiGuide)	AGCTGCCCGAGCGCGCCCCGCGG	PYDC1	ENSG00000169900	2.10107731042961	[]	[]	2	hSpCas9	negative selection	3658640
31216941	31216964	16	-	26780180	A375	viability (Avana lentiGuide)	GTTCAAGATGAAGCTGGGGACGG	PYDC1	ENSG00000169900	0.35383514949917	[]	[]	0	hSpCas9	negative selection	3658641
31216987	31217010	16	+	26780180	A375	viability (Avana lentiGuide)	GTTCTCCAGCACCTTCAGGATGG	PYDC1	ENSG00000169900	4.04842326463919	[]	[]	4	hSpCas9	negative selection	3658642
31216925	31216948	16	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGGACGGTGCCGCTGCGCGAGGG	PYDC1	ENSG00000169900	0.0618534663982227	[4]	[5,4]	1	hSpCas9	positive selection	3767244
31216977	31217000	16	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGTGCTGGAGAACCTGACACCGG	PYDC1	ENSG00000169900	-0.08218647039209737	[5]	[5,4]	-1	hSpCas9	positive selection	3767245
31216904	31216927	16	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGCTTTGAGCGCATCCCGCGGGG	PYDC1	ENSG00000169900	-0.17680312377631363	[4]	[4,2]	-3	hSpCas9	positive selection	3767246
31216889	31216912	16	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AGCTGCCCGAGCGCGCCCCGCGG	PYDC1	ENSG00000169900	0.3766795172931824	[5]	[6,6]	9	hSpCas9	positive selection	3767247
31216941	31216964	16	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GTTCAAGATGAAGCTGGGGACGG	PYDC1	ENSG00000169900	0.08298612275909809	[5]	[6,5]	2	hSpCas9	positive selection	3767248
31216987	31217010	16	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GTTCTCCAGCACCTTCAGGATGG	PYDC1	ENSG00000169900	-0.3597434650254361	[4]	[3,2]	-5	hSpCas9	positive selection	3767249
31216925	31216948	16	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGGACGGTGCCGCTGCGCGAGGG	PYDC1	ENSG00000169900	-0.21876097640790435	[5]	[3,3]	-3	hSpCas9	positive selection	3875851
31216977	31217000	16	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGTGCTGGAGAACCTGACACCGG	PYDC1	ENSG00000169900	-0.3858742109299803	[6]	[2,4]	-5	hSpCas9	positive selection	3875852
31216904	31216927	16	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGCTTTGAGCGCATCCCGCGGGG	PYDC1	ENSG00000169900	0.32328555246029317	[5]	[5,5]	8	hSpCas9	positive selection	3875853
31216889	31216912	16	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AGCTGCCCGAGCGCGCCCCGCGG	PYDC1	ENSG00000169900	0.3210586387806766	[5]	[6,5]	8	hSpCas9	positive selection	3875854
31216941	31216964	16	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GTTCAAGATGAAGCTGGGGACGG	PYDC1	ENSG00000169900	0.08531568192175304	[6]	[5,5]	1	hSpCas9	positive selection	3875855
31216987	31217010	16	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GTTCTCCAGCACCTTCAGGATGG	PYDC1	ENSG00000169900	-0.04455304623032952	[5]	[2,4]	0	hSpCas9	positive selection	3875856
31216795	31216818	16	+	26780180	A375	viability	CATGCGCATGTCGCGCAGCACGG	PYDC1	ENSG00000169900	1.15406677507126	[]	[]	6	hSpCas9	negative selection	3986274
31216818	31216841	16	-	26780180	A375	viability	CTACGCAGCCGAGCTCGTCGTGG	PYDC1	ENSG00000169900	1.45245536334074	[]	[]	8	hSpCas9	negative selection	3986275
31216878	31216901	16	-	26780180	A375	viability	GCTCGGGCAGCTAGATATCGTGG	PYDC1	ENSG00000169900	1.20247404857365	[]	[]	6	hSpCas9	negative selection	3986276
31216791	31216814	16	-	26780180	A375	viability	GCTGCGCGACATGCGCATGTTGG	PYDC1	ENSG00000169900	0.597879493542776	[]	[]	1	hSpCas9	negative selection	3986277
31217008	31217031	16	+	26780180	A375	viability	GGCCTCGCGCTTCGTTCCCATGG	PYDC1	ENSG00000169900	0.19517544114766	[]	[]	0	hSpCas9	negative selection	3986278
31216831	31216854	16	+	26780180	A375	viability	GGCTGCGTAGTCCTCGTAGTAGG	PYDC1	ENSG00000169900	0.425877155140215	[]	[]	1	hSpCas9	negative selection	3986279
31216795	31216818	16	+	26780180	HT29	viability (GeCKOv2 library)	CATGCGCATGTCGCGCAGCACGG	PYDC1	ENSG00000169900	1.19910487640619	[]	[]	6	hSpCas9	negative selection	4094240
31216818	31216841	16	-	26780180	HT29	viability (GeCKOv2 library)	CTACGCAGCCGAGCTCGTCGTGG	PYDC1	ENSG00000169900	1.66965982166693	[]	[]	8	hSpCas9	negative selection	4094241
31216878	31216901	16	-	26780180	HT29	viability (GeCKOv2 library)	GCTCGGGCAGCTAGATATCGTGG	PYDC1	ENSG00000169900	0.807331889730103	[]	[]	3	hSpCas9	negative selection	4094242
31216791	31216814	16	-	26780180	HT29	viability (GeCKOv2 library)	GCTGCGCGACATGCGCATGTTGG	PYDC1	ENSG00000169900	1.0197335419712	[]	[]	4	hSpCas9	negative selection	4094243
31217008	31217031	16	+	26780180	HT29	viability (GeCKOv2 library)	GGCCTCGCGCTTCGTTCCCATGG	PYDC1	ENSG00000169900	0.809804988624951	[]	[]	3	hSpCas9	negative selection	4094244
31216831	31216854	16	+	26780180	HT29	viability (GeCKOv2 library)	GGCTGCGTAGTCCTCGTAGTAGG	PYDC1	ENSG00000169900	0.68672557468718	[]	[]	2	hSpCas9	negative selection	4094245
31216878	31216901	16	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GCTCGGGCAGCTAGATATCGTGG	PYDC1	ENSG00000169900	-0.2172395854961425	[3]	[2,1]	-5	hSpCas9	positive selection	4164404
31216831	31216854	16	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GGCTGCGTAGTCCTCGTAGTAGG	PYDC1	ENSG00000169900	-0.037855039054459	[4]	[2,2]	-1	hSpCas9	positive selection	4164405
31216878	31216901	16	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GCTCGGGCAGCTAGATATCGTGG	PYDC1	ENSG00000169900	-0.3116749525560524	[2]	[0,0,0,0]	-5	hSpCas9	positive selection	4228426
31216831	31216854	16	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GGCTGCGTAGTCCTCGTAGTAGG	PYDC1	ENSG00000169900	1.081484787850149	[4]	[3,2,3,4]	7	hSpCas9	positive selection	4228427
31216791	31216814	16	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GCTGCGCGACATGCGCATGTTGG	PYDC1	ENSG00000169900	0.4155941217550073	[3]	[3,3]	8	hSpCas9	positive selection	4293313
31216795	31216818	16	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CATGCGCATGTCGCGCAGCACGG	PYDC1	ENSG00000169900	-0.4386964775520486	[2]	[1,0]	-7	hSpCas9	positive selection	4293314
31216831	31216854	16	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GGCTGCGTAGTCCTCGTAGTAGG	PYDC1	ENSG00000169900	0.23133998571812173	[3]	[2,3]	4	hSpCas9	positive selection	4293315
31216878	31216901	16	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GCTCGGGCAGCTAGATATCGTGG	PYDC1	ENSG00000169900	0.2133169849882564	[1]	[1,1]	4	hSpCas9	positive selection	4357571
31217008	31217031	16	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GGCCTCGCGCTTCGTTCCCATGG	PYDC1	ENSG00000169900	0.04595568319875265	[2]	[3,0]	0	hSpCas9	positive selection	4357572
31216818	31216841	16	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CTACGCAGCCGAGCTCGTCGTGG	PYDC1	ENSG00000169900	-0.2997861429683404	[3]	[3,0]	-6	hSpCas9	positive selection	4357573
31216835	31216857	16	+	27760321	OCIAML3	viability	GCGTAGTCCTCGTAGTAGGAGG	PYDC1	ENSG00000169900	-0.27577820285810806	[393,309]	[198,260]	-3	hSpCas9	negative selection	4432249
31216855	31216877	16	+	27760321	OCIAML3	viability	GGCGACCAGCTTGTCGGTGAGG	PYDC1	ENSG00000169900	0.295455720136255	[714,612]	[670,588]	3	hSpCas9	negative selection	4432250
31216878	31216900	16	-	27760321	OCIAML3	viability	CTCGGGCAGCTAGATATCGTGG	PYDC1	ENSG00000169900	0.08098148118506676	[707,582]	[458,625]	0	hSpCas9	negative selection	4432251
31216904	31216926	16	-	27760321	OCIAML3	viability	GCTTTGAGCGCATCCCGCGGGG	PYDC1	ENSG00000169900	0.2986179327837737	[1226,1142]	[822,1553]	3	hSpCas9	negative selection	4432252
31216925	31216947	16	-	27760321	OCIAML3	viability	GGACGGTGCCGCTGCGCGAGGG	PYDC1	ENSG00000169900	-0.14524314169944774	[861,851]	[480,772]	-1	hSpCas9	negative selection	4432253
31216835	31216857	16	+	27760321	OCIAML2	viability	GCGTAGTCCTCGTAGTAGGAGG	PYDC1	ENSG00000169900	-0.32848473052626437	[393,309]	[223,226]	-4	hSpCas9	negative selection	4515712
31216855	31216877	16	+	27760321	OCIAML2	viability	GGCGACCAGCTTGTCGGTGAGG	PYDC1	ENSG00000169900	0.13121319481296267	[714,612]	[510,685]	1	hSpCas9	negative selection	4515713
31216878	31216900	16	-	27760321	OCIAML2	viability	CTCGGGCAGCTAGATATCGTGG	PYDC1	ENSG00000169900	-0.025209512047561278	[707,582]	[401,653]	0	hSpCas9	negative selection	4515714
31216904	31216926	16	-	27760321	OCIAML2	viability	GCTTTGAGCGCATCCCGCGGGG	PYDC1	ENSG00000169900	0.23434819750696279	[1226,1142]	[964,1342]	3	hSpCas9	negative selection	4515715
31216925	31216947	16	-	27760321	OCIAML2	viability	GGACGGTGCCGCTGCGCGAGGG	PYDC1	ENSG00000169900	-0.1016080863397858	[861,851]	[530,801]	-1	hSpCas9	negative selection	4515716
31216835	31216857	16	+	27760321	MV411	viability	GCGTAGTCCTCGTAGTAGGAGG	PYDC1	ENSG00000169900	0.4617931058725658	[393,309]	[356,258]	3	hSpCas9	negative selection	4599175
31216855	31216877	16	+	27760321	MV411	viability	GGCGACCAGCTTGTCGGTGAGG	PYDC1	ENSG00000169900	0.7871739164717523	[714,612]	[595,990]	6	hSpCas9	negative selection	4599176
31216878	31216900	16	-	27760321	MV411	viability	CTCGGGCAGCTAGATATCGTGG	PYDC1	ENSG00000169900	-0.5497325696043112	[707,582]	[96,578]	-4	hSpCas9	negative selection	4599177
31216904	31216926	16	-	27760321	MV411	viability	GCTTTGAGCGCATCCCGCGGGG	PYDC1	ENSG00000169900	0.7697945998628957	[1226,1142]	[1334,1331]	5	hSpCas9	negative selection	4599178
31216925	31216947	16	-	27760321	MV411	viability	GGACGGTGCCGCTGCGCGAGGG	PYDC1	ENSG00000169900	0.26090194824175217	[861,851]	[607,786]	1	hSpCas9	negative selection	4599179
31216835	31216857	16	+	27760321	HL60	viability	GCGTAGTCCTCGTAGTAGGAGG	PYDC1	ENSG00000169900	-0.5723888025426626	[393,309]	[228,152]	-6	hSpCas9	negative selection	4682638
31216855	31216877	16	+	27760321	HL60	viability	GGCGACCAGCTTGTCGGTGAGG	PYDC1	ENSG00000169900	0.3660619774049987	[714,612]	[678,715]	4	hSpCas9	negative selection	4682639
31216878	31216900	16	-	27760321	HL60	viability	CTCGGGCAGCTAGATATCGTGG	PYDC1	ENSG00000169900	-0.30533912603949676	[707,582]	[398,451]	-3	hSpCas9	negative selection	4682640
31216904	31216926	16	-	27760321	HL60	viability	GCTTTGAGCGCATCCCGCGGGG	PYDC1	ENSG00000169900	0.4015577296380892	[1226,1142]	[1084,1484]	5	hSpCas9	negative selection	4682641
31216925	31216947	16	-	27760321	HL60	viability	GGACGGTGCCGCTGCGCGAGGG	PYDC1	ENSG00000169900	-0.24918723529223252	[861,851]	[562,619]	-3	hSpCas9	negative selection	4682642
31216835	31216857	16	+	27760321	HT1080	viability	GCGTAGTCCTCGTAGTAGGAGG	PYDC1	ENSG00000169900	-2.984909112336618	[309,241]	[0,27]	-7	hSpCas9	negative selection	4766101
31216855	31216877	16	+	27760321	HT1080	viability	GGCGACCAGCTTGTCGGTGAGG	PYDC1	ENSG00000169900	0.06654112323659445	[612,478]	[370,70]	0	hSpCas9	negative selection	4766102
31216878	31216900	16	-	27760321	HT1080	viability	CTCGGGCAGCTAGATATCGTGG	PYDC1	ENSG00000169900	0.6713633847843796	[582,454]	[334,322]	3	hSpCas9	negative selection	4766103
31216904	31216926	16	-	27760321	HT1080	viability	GCTTTGAGCGCATCCCGCGGGG	PYDC1	ENSG00000169900	-0.35715766052325404	[1142,891]	[209,432]	-2	hSpCas9	negative selection	4766104
31216925	31216947	16	-	27760321	HT1080	viability	GGACGGTGCCGCTGCGCGAGGG	PYDC1	ENSG00000169900	0.07623136667730268	[851,664]	[361,270]	0	hSpCas9	negative selection	4766105
31216835	31216857	16	+	27760321	HT29	viability after 7 days	GCGTAGTCCTCGTAGTAGGAGG	PYDC1	ENSG00000169900	-0.0236204828188612	[309,241]	[253,390,386]	0	hSpCas9	negative selection	4849564
31216855	31216877	16	+	27760321	HT29	viability after 7 days	GGCGACCAGCTTGTCGGTGAGG	PYDC1	ENSG00000169900	0.2569420316014912	[612,478]	[717,868,908]	4	hSpCas9	negative selection	4849565
31216878	31216900	16	-	27760321	HT29	viability after 7 days	CTCGGGCAGCTAGATATCGTGG	PYDC1	ENSG00000169900	0.5186947470006931	[582,454]	[1162,773,958]	7	hSpCas9	negative selection	4849566
31216904	31216926	16	-	27760321	HT29	viability after 7 days	GCTTTGAGCGCATCCCGCGGGG	PYDC1	ENSG00000169900	-0.41329472680366064	[1142,891]	[1141,1213,623]	-6	hSpCas9	negative selection	4849567
31216925	31216947	16	-	27760321	HT29	viability after 7 days	GGACGGTGCCGCTGCGCGAGGG	PYDC1	ENSG00000169900	0.08787704800700125	[851,664]	[1045,986,1074]	1	hSpCas9	negative selection	4849568
31216835	31216857	16	+	27760321	HT29	viability after 25 days	GCGTAGTCCTCGTAGTAGGAGG	PYDC1	ENSG00000169900	0.29364492401292575	[309,241]	[375,396,386]	3	hSpCas9	negative selection	4933027
31216855	31216877	16	+	27760321	HT29	viability after 25 days	GGCGACCAGCTTGTCGGTGAGG	PYDC1	ENSG00000169900	0.484280824710957	[612,478]	[412,1381,848]	5	hSpCas9	negative selection	4933028
31216878	31216900	16	-	27760321	HT29	viability after 25 days	CTCGGGCAGCTAGATATCGTGG	PYDC1	ENSG00000169900	0.3839180262406312	[582,454]	[996,592,709]	4	hSpCas9	negative selection	4933029
31216904	31216926	16	-	27760321	HT29	viability after 25 days	GCTTTGAGCGCATCCCGCGGGG	PYDC1	ENSG00000169900	0.1547747615449262	[1142,891]	[1617,1156,1061]	1	hSpCas9	negative selection	4933030
31216925	31216947	16	-	27760321	HT29	viability after 25 days	GGACGGTGCCGCTGCGCGAGGG	PYDC1	ENSG00000169900	0.00860582526513598	[851,664]	[735,1017,868]	0	hSpCas9	negative selection	4933031
31216835	31216857	16	+	27760321	HT29	viability after 22 days	GCGTAGTCCTCGTAGTAGGAGG	PYDC1	ENSG00000169900	0.2812718195862276	[309,241]	[310,501,351]	3	hSpCas9	negative selection	5016490
31216855	31216877	16	+	27760321	HT29	viability after 22 days	GGCGACCAGCTTGTCGGTGAGG	PYDC1	ENSG00000169900	0.06680924319430914	[612,478]	[386,1035,566]	0	hSpCas9	negative selection	5016491
31216878	31216900	16	-	27760321	HT29	viability after 22 days	CTCGGGCAGCTAGATATCGTGG	PYDC1	ENSG00000169900	0.1199800142738231	[582,454]	[772,502,676]	1	hSpCas9	negative selection	5016492
31216904	31216926	16	-	27760321	HT29	viability after 22 days	GCTTTGAGCGCATCCCGCGGGG	PYDC1	ENSG00000169900	0.15410884470175978	[1142,891]	[1419,1464,1035]	1	hSpCas9	negative selection	5016493
31216925	31216947	16	-	27760321	HT29	viability after 22 days	GGACGGTGCCGCTGCGCGAGGG	PYDC1	ENSG00000169900	-0.2014693037355002	[851,664]	[657,925,705]	-2	hSpCas9	negative selection	5016494
31216835	31216857	16	+	27760321	HT29	viability after 19 days	GCGTAGTCCTCGTAGTAGGAGG	PYDC1	ENSG00000169900	-0.19346056668917705	[309,241]	[410,152,277]	-2	hSpCas9	negative selection	5099953
31216855	31216877	16	+	27760321	HT29	viability after 19 days	GGCGACCAGCTTGTCGGTGAGG	PYDC1	ENSG00000169900	0.019270135805873556	[612,478]	[582,622,684]	0	hSpCas9	negative selection	5099954
31216878	31216900	16	-	27760321	HT29	viability after 19 days	CTCGGGCAGCTAGATATCGTGG	PYDC1	ENSG00000169900	0.09217075142712827	[582,454]	[666,538,692]	0	hSpCas9	negative selection	5099955
31216904	31216926	16	-	27760321	HT29	viability after 19 days	GCTTTGAGCGCATCCCGCGGGG	PYDC1	ENSG00000169900	0.15064943563395805	[1142,891]	[1530,1465,916]	1	hSpCas9	negative selection	5099956
31216925	31216947	16	-	27760321	HT29	viability after 19 days	GGACGGTGCCGCTGCGCGAGGG	PYDC1	ENSG00000169900	0.2383674124393773	[851,664]	[878,1119,1053]	2	hSpCas9	negative selection	5099957
31216835	31216857	16	+	27760321	HT29	viability after 16 days	GCGTAGTCCTCGTAGTAGGAGG	PYDC1	ENSG00000169900	-0.195382547815161	[309,241]	[299,302,207]	-2	hSpCas9	negative selection	5183416
31216855	31216877	16	+	27760321	HT29	viability after 16 days	GGCGACCAGCTTGTCGGTGAGG	PYDC1	ENSG00000169900	0.5033030116560185	[612,478]	[875,851,870]	6	hSpCas9	negative selection	5183417
31216878	31216900	16	-	27760321	HT29	viability after 16 days	CTCGGGCAGCTAGATATCGTGG	PYDC1	ENSG00000169900	0.006644551552389855	[582,454]	[625,504,624]	0	hSpCas9	negative selection	5183418
31216904	31216926	16	-	27760321	HT29	viability after 16 days	GCTTTGAGCGCATCCCGCGGGG	PYDC1	ENSG00000169900	0.23421566249449066	[1142,891]	[1271,1666,1062]	2	hSpCas9	negative selection	5183419
31216925	31216947	16	-	27760321	HT29	viability after 16 days	GGACGGTGCCGCTGCGCGAGGG	PYDC1	ENSG00000169900	0.0589627085388722	[851,664]	[673,1039,913]	0	hSpCas9	negative selection	5183420
31216835	31216857	16	+	27760321	HT29	viability after 13 days	GCGTAGTCCTCGTAGTAGGAGG	PYDC1	ENSG00000169900	-0.2791463185517839	[309,241]	[179,232,371]	-3	hSpCas9	negative selection	5266879
31216855	31216877	16	+	27760321	HT29	viability after 13 days	GGCGACCAGCTTGTCGGTGAGG	PYDC1	ENSG00000169900	0.2235590934939774	[612,478]	[642,733,835]	2	hSpCas9	negative selection	5266880
31216878	31216900	16	-	27760321	HT29	viability after 13 days	CTCGGGCAGCTAGATATCGTGG	PYDC1	ENSG00000169900	0.3654791274585294	[582,454]	[797,874,660]	4	hSpCas9	negative selection	5266881
31216904	31216926	16	-	27760321	HT29	viability after 13 days	GCTTTGAGCGCATCCCGCGGGG	PYDC1	ENSG00000169900	-0.20792332853370898	[1142,891]	[1130,1074,868]	-2	hSpCas9	negative selection	5266882
31216925	31216947	16	-	27760321	HT29	viability after 13 days	GGACGGTGCCGCTGCGCGAGGG	PYDC1	ENSG00000169900	-0.13147461712288921	[851,664]	[801,910,702]	-1	hSpCas9	negative selection	5266883
31216835	31216857	16	+	27760321	HT29	viability after 10 days	GCGTAGTCCTCGTAGTAGGAGG	PYDC1	ENSG00000169900	-0.14335261272884586	[309,241]	[198,382,354]	-2	hSpCas9	negative selection	5350342
31216855	31216877	16	+	27760321	HT29	viability after 10 days	GGCGACCAGCTTGTCGGTGAGG	PYDC1	ENSG00000169900	0.1690173629833548	[612,478]	[627,820,849]	2	hSpCas9	negative selection	5350343
31216878	31216900	16	-	27760321	HT29	viability after 10 days	CTCGGGCAGCTAGATATCGTGG	PYDC1	ENSG00000169900	0.11537764122262939	[582,454]	[746,646,709]	1	hSpCas9	negative selection	5350344
31216904	31216926	16	-	27760321	HT29	viability after 10 days	GCTTTGAGCGCATCCCGCGGGG	PYDC1	ENSG00000169900	0.06468631840711181	[1142,891]	[1068,1509,1409]	0	hSpCas9	negative selection	5350345
31216925	31216947	16	-	27760321	HT29	viability after 10 days	GGACGGTGCCGCTGCGCGAGGG	PYDC1	ENSG00000169900	-0.08118920080681291	[851,664]	[1057,932,699]	-1	hSpCas9	negative selection	5350346
31216835	31216857	16	+	27760321	MOLM13	viability	GCGTAGTCCTCGTAGTAGGAGG	PYDC1	ENSG00000169900	-0.8407815778891361	[393,309]	[33,174]	-5	hSpCas9	negative selection	5433805
31216855	31216877	16	+	27760321	MOLM13	viability	GGCGACCAGCTTGTCGGTGAGG	PYDC1	ENSG00000169900	0.675249620744511	[714,612]	[657,543]	5	hSpCas9	negative selection	5433806
31216878	31216900	16	-	27760321	MOLM13	viability	CTCGGGCAGCTAGATATCGTGG	PYDC1	ENSG00000169900	0.27884841119851167	[707,582]	[435,442]	2	hSpCas9	negative selection	5433807
31216904	31216926	16	-	27760321	MOLM13	viability	GCTTTGAGCGCATCCCGCGGGG	PYDC1	ENSG00000169900	0.561095327855488	[1226,1142]	[1083,903]	4	hSpCas9	negative selection	5433808
31216925	31216947	16	-	27760321	MOLM13	viability	GGACGGTGCCGCTGCGCGAGGG	PYDC1	ENSG00000169900	-0.3490119264082133	[861,851]	[505,273]	-2	hSpCas9	negative selection	5433809
31216625	31216648	16	+	27661255	K562	viability	GAGGTCTGAGGGAGGACCCCAGG	PYDC1	ENSG00000169900	-0.10814549991092062	[680,682]	[553,463]	-4	dCas9-KRAB	negative selection	5505497
31216639	31216662	16	+	27661255	K562	viability	GACCCCAGGAGGGACCCTGAAGG	PYDC1	ENSG00000169900	-0.6188931855223746	[555,497]	[285,264]	-8	dCas9-KRAB	negative selection	5505498
31217068	31217091	16	-	27661255	K562	viability	GCAGGAAAGGTAGGACCTGATGG	PYDC1	ENSG00000169900	0.0009365928416134872	[733,895]	[694,609]	0	dCas9-KRAB	negative selection	5505499
31216791	31216814	16	-	27260156	BXPC3	viability	GCTGCGCGACATGCGCATGTTGG	PYDC1	ENSG00000169900	0.44066997928373597	[659]	[876,889,964,1028]	8	hSpCas9	negative selection	5565773
31216795	31216818	16	+	27260156	BXPC3	viability	CATGCGCATGTCGCGCAGCACGG	PYDC1	ENSG00000169900	0.29175066761051416	[237]	[362,272,279,293]	6	hSpCas9	negative selection	5565774
31216831	31216854	16	+	27260156	BXPC3	viability	GGCTGCGTAGTCCTCGTAGTAGG	PYDC1	ENSG00000169900	0.2577370370639291	[632]	[731,789,715,945]	5	hSpCas9	negative selection	5565775
31216878	31216901	16	-	27260156	BXPC3	viability	GCTCGGGCAGCTAGATATCGTGG	PYDC1	ENSG00000169900	-0.29616631838526586	[138]	[99,88,155,133]	-6	hSpCas9	negative selection	5630031
31217008	31217031	16	+	27260156	BXPC3	viability	GGCCTCGCGCTTCGTTCCCATGG	PYDC1	ENSG00000169900	0.28652053620207096	[265]	[326,303,353,377]	6	hSpCas9	negative selection	5630032
31216818	31216841	16	-	27260156	BXPC3	viability	CTACGCAGCCGAGCTCGTCGTGG	PYDC1	ENSG00000169900	-0.024074034419072687	[527]	[562,483,470,664]	0	hSpCas9	negative selection	5630033
31216791	31216814	16	-	27260156	A673	viability	GCTGCGCGACATGCGCATGTTGG	PYDC1	ENSG00000169900	0.13609754105803373	[659]	[976,896,755,863]	3	hSpCas9	negative selection	5687024
31216795	31216818	16	+	27260156	A673	viability	CATGCGCATGTCGCGCAGCACGG	PYDC1	ENSG00000169900	0.2415097076886541	[237]	[388,280,320,368]	6	hSpCas9	negative selection	5687025
31216831	31216854	16	+	27260156	A673	viability	GGCTGCGTAGTCCTCGTAGTAGG	PYDC1	ENSG00000169900	-0.008988313775063206	[632]	[903,660,701,773]	0	hSpCas9	negative selection	5687026
31216878	31216901	16	-	27260156	A673	viability	GCTCGGGCAGCTAGATATCGTGG	PYDC1	ENSG00000169900	-0.25436565122620736	[138]	[164,132,162,98]	-6	hSpCas9	negative selection	5751282
31217008	31217031	16	+	27260156	A673	viability	GGCCTCGCGCTTCGTTCCCATGG	PYDC1	ENSG00000169900	0.25518431904038197	[265]	[510,326,320,381]	6	hSpCas9	negative selection	5751283
31216818	31216841	16	-	27260156	A673	viability	CTACGCAGCCGAGCTCGTCGTGG	PYDC1	ENSG00000169900	-0.09806003586842413	[527]	[653,597,525,597]	-2	hSpCas9	negative selection	5751284
31216791	31216814	16	-	27260156	A375	viability	GCTGCGCGACATGCGCATGTTGG	PYDC1	ENSG00000169900	0.42395839314711903	[659]	[1197,920,1045,961]	6	hSpCas9	negative selection	5808275
31216795	31216818	16	+	27260156	A375	viability	CATGCGCATGTCGCGCAGCACGG	PYDC1	ENSG00000169900	0.30037329328475804	[237]	[457,430,240,260]	4	hSpCas9	negative selection	5808276
31216831	31216854	16	+	27260156	A375	viability	GGCTGCGTAGTCCTCGTAGTAGG	PYDC1	ENSG00000169900	0.10671160388110051	[632]	[846,806,786,747]	1	hSpCas9	negative selection	5808277
31216878	31216901	16	-	27260156	A375	viability	GCTCGGGCAGCTAGATATCGTGG	PYDC1	ENSG00000169900	-1.1608850649873574	[138]	[28,57,129,70]	-8	hSpCas9	negative selection	5872533
31217008	31217031	16	+	27260156	A375	viability	GGCCTCGCGCTTCGTTCCCATGG	PYDC1	ENSG00000169900	0.4120992995431615	[265]	[236,425,580,408]	6	hSpCas9	negative selection	5872534
31216818	31216841	16	-	27260156	A375	viability	CTACGCAGCCGAGCTCGTCGTGG	PYDC1	ENSG00000169900	0.1568558341468351	[527]	[553,1116,556,589]	2	hSpCas9	negative selection	5872535
31216791	31216814	16	-	27260156	COLO741	viability	GCTGCGCGACATGCGCATGTTGG	PYDC1	ENSG00000169900	0.4012737888208624	[659]	[1163,1109,1071]	7	hSpCas9	negative selection	5929526
31216795	31216818	16	+	27260156	COLO741	viability	CATGCGCATGTCGCGCAGCACGG	PYDC1	ENSG00000169900	0.10614487172749398	[237]	[340,392,253]	2	hSpCas9	negative selection	5929527
31216831	31216854	16	+	27260156	COLO741	viability	GGCTGCGTAGTCCTCGTAGTAGG	PYDC1	ENSG00000169900	0.3151988504336241	[632]	[1209,1047,791]	6	hSpCas9	negative selection	5929528
31216878	31216901	16	-	27260156	COLO741	viability	GCTCGGGCAGCTAGATATCGTGG	PYDC1	ENSG00000169900	-0.8403454991384127	[138]	[89,126,80]	-9	hSpCas9	negative selection	5993784
31217008	31217031	16	+	27260156	COLO741	viability	GGCCTCGCGCTTCGTTCCCATGG	PYDC1	ENSG00000169900	0.39681788619940067	[265]	[428,464,445]	7	hSpCas9	negative selection	5993785
31216818	31216841	16	-	27260156	COLO741	viability	CTACGCAGCCGAGCTCGTCGTGG	PYDC1	ENSG00000169900	-0.03676855261979853	[527]	[668,625,675]	-1	hSpCas9	negative selection	5993786
31216791	31216814	16	-	27260156	CAL120	viability	GCTGCGCGACATGCGCATGTTGG	PYDC1	ENSG00000169900	0.18317323091260151	[659]	[983,954,866]	2	hSpCas9	negative selection	6050777
31216795	31216818	16	+	27260156	CAL120	viability	CATGCGCATGTCGCGCAGCACGG	PYDC1	ENSG00000169900	0.6457817177495857	[237]	[892,233,329]	8	hSpCas9	negative selection	6050778
31216831	31216854	16	+	27260156	CAL120	viability	GGCTGCGTAGTCCTCGTAGTAGG	PYDC1	ENSG00000169900	0.13863896512889845	[632]	[795,849,942]	2	hSpCas9	negative selection	6050779
31216878	31216901	16	-	27260156	CAL120	viability	GCTCGGGCAGCTAGATATCGTGG	PYDC1	ENSG00000169900	-2.140321836429483	[138]	[34,39,41]	-9	hSpCas9	negative selection	6115035
31217008	31217031	16	+	27260156	CAL120	viability	GGCCTCGCGCTTCGTTCCCATGG	PYDC1	ENSG00000169900	1.1266088022240988	[265]	[291,1417,398]	9	hSpCas9	negative selection	6115036
31216818	31216841	16	-	27260156	CAL120	viability	CTACGCAGCCGAGCTCGTCGTGG	PYDC1	ENSG00000169900	-0.16651513992759706	[527]	[631,600,530]	-2	hSpCas9	negative selection	6115037
31216791	31216814	16	-	27260156	CADOES1	viability	GCTGCGCGACATGCGCATGTTGG	PYDC1	ENSG00000169900	0.09876437174569397	[659]	[741,655,678,547]	1	hSpCas9	negative selection	6172028
31216795	31216818	16	+	27260156	CADOES1	viability	CATGCGCATGTCGCGCAGCACGG	PYDC1	ENSG00000169900	0.22907818567287752	[237]	[170,278,252,337]	4	hSpCas9	negative selection	6172029
31216831	31216854	16	+	27260156	CADOES1	viability	GGCTGCGTAGTCCTCGTAGTAGG	PYDC1	ENSG00000169900	-0.1018196065604492	[632]	[463,534,483,717]	-2	hSpCas9	negative selection	6172030
31216878	31216901	16	-	27260156	CADOES1	viability	GCTCGGGCAGCTAGATATCGTGG	PYDC1	ENSG00000169900	-1.1827656026909976	[138]	[55,30,76,63]	-9	hSpCas9	negative selection	6236286
31217008	31217031	16	+	27260156	CADOES1	viability	GGCCTCGCGCTTCGTTCCCATGG	PYDC1	ENSG00000169900	0.07901875585047169	[265]	[251,276,263,251]	1	hSpCas9	negative selection	6236287
31216818	31216841	16	-	27260156	CADOES1	viability	CTACGCAGCCGAGCTCGTCGTGG	PYDC1	ENSG00000169900	-0.1900285356935128	[527]	[321,407,384,613]	-3	hSpCas9	negative selection	6236288
31216791	31216814	16	-	27260156	EWS502	viability	GCTGCGCGACATGCGCATGTTGG	PYDC1	ENSG00000169900	0.1849027497736776	[659]	[560,918,742,988]	3	hSpCas9	negative selection	6293279
31216795	31216818	16	+	27260156	EWS502	viability	CATGCGCATGTCGCGCAGCACGG	PYDC1	ENSG00000169900	0.2350036773706803	[237]	[169,266,447,320]	4	hSpCas9	negative selection	6293280
31216831	31216854	16	+	27260156	EWS502	viability	GGCTGCGTAGTCCTCGTAGTAGG	PYDC1	ENSG00000169900	0.01803743645981748	[632]	[607,688,682,745]	0	hSpCas9	negative selection	6293281
31216878	31216901	16	-	27260156	EWS502	viability	GCTCGGGCAGCTAGATATCGTGG	PYDC1	ENSG00000169900	-0.8180146402732575	[138]	[30,42,139,131]	-8	hSpCas9	negative selection	6357537
31217008	31217031	16	+	27260156	EWS502	viability	GGCCTCGCGCTTCGTTCCCATGG	PYDC1	ENSG00000169900	0.10789506346181599	[265]	[274,349,231,360]	1	hSpCas9	negative selection	6357538
31216818	31216841	16	-	27260156	EWS502	viability	CTACGCAGCCGAGCTCGTCGTGG	PYDC1	ENSG00000169900	0.19599683559224249	[527]	[501,635,659,789]	3	hSpCas9	negative selection	6357539
31216791	31216814	16	-	27260156	EW8	viability	GCTGCGCGACATGCGCATGTTGG	PYDC1	ENSG00000169900	0.1687291448923769	[659]	[669,667,405,699]	3	hSpCas9	negative selection	6414530
31216795	31216818	16	+	27260156	EW8	viability	CATGCGCATGTCGCGCAGCACGG	PYDC1	ENSG00000169900	0.10322440091756724	[237]	[309,214,169,150]	2	hSpCas9	negative selection	6414531
31216831	31216854	16	+	27260156	EW8	viability	GGCTGCGTAGTCCTCGTAGTAGG	PYDC1	ENSG00000169900	0.0945398815080159	[632]	[541,657,376,640]	1	hSpCas9	negative selection	6414532
31216878	31216901	16	-	27260156	EW8	viability	GCTCGGGCAGCTAGATATCGTGG	PYDC1	ENSG00000169900	0.33727232362827664	[138]	[133,276,69,99]	6	hSpCas9	negative selection	6478788
31217008	31217031	16	+	27260156	EW8	viability	GGCCTCGCGCTTCGTTCCCATGG	PYDC1	ENSG00000169900	0.14828452002706394	[265]	[310,253,155,255]	2	hSpCas9	negative selection	6478789
31216818	31216841	16	-	27260156	EW8	viability	CTACGCAGCCGAGCTCGTCGTGG	PYDC1	ENSG00000169900	-0.2820602061713888	[527]	[393,370,336,311]	-5	hSpCas9	negative selection	6478790
31216791	31216814	16	-	27260156	CORL105	viability	GCTGCGCGACATGCGCATGTTGG	PYDC1	ENSG00000169900	0.22315067841163916	[659]	[861,934,787,1001]	4	hSpCas9	negative selection	6535781
31216795	31216818	16	+	27260156	CORL105	viability	CATGCGCATGTCGCGCAGCACGG	PYDC1	ENSG00000169900	0.30935178686112563	[237]	[455,393,223,290]	6	hSpCas9	negative selection	6535782
31216831	31216854	16	+	27260156	CORL105	viability	GGCTGCGTAGTCCTCGTAGTAGG	PYDC1	ENSG00000169900	-0.18207337856531813	[632]	[637,569,701,710]	-3	hSpCas9	negative selection	6535783
31216878	31216901	16	-	27260156	CORL105	viability	GCTCGGGCAGCTAGATATCGTGG	PYDC1	ENSG00000169900	-0.22294104540050186	[138]	[103,132,136,181]	-4	hSpCas9	negative selection	6600039
31217008	31217031	16	+	27260156	CORL105	viability	GGCCTCGCGCTTCGTTCCCATGG	PYDC1	ENSG00000169900	-0.23007729286913958	[265]	[292,264,246,254]	-4	hSpCas9	negative selection	6600040
31216818	31216841	16	-	27260156	CORL105	viability	CTACGCAGCCGAGCTCGTCGTGG	PYDC1	ENSG00000169900	-0.1721253869936473	[527]	[478,576,497,628]	-3	hSpCas9	negative selection	6600041
31216791	31216814	16	-	27260156	HS294T	viability	GCTGCGCGACATGCGCATGTTGG	PYDC1	ENSG00000169900	0.34337217342042403	[659]	[390,297,246,357]	4	hSpCas9	negative selection	6657032
31216795	31216818	16	+	27260156	HS294T	viability	CATGCGCATGTCGCGCAGCACGG	PYDC1	ENSG00000169900	0.1585934302914277	[237]	[112,60,123,114]	2	hSpCas9	negative selection	6657033
31216831	31216854	16	+	27260156	HS294T	viability	GGCTGCGTAGTCCTCGTAGTAGG	PYDC1	ENSG00000169900	0.18668014469990885	[632]	[304,262,265,276]	2	hSpCas9	negative selection	6657034
31216878	31216901	16	-	27260156	HS294T	viability	GCTCGGGCAGCTAGATATCGTGG	PYDC1	ENSG00000169900	-0.8364207436111923	[138]	[13,44,28,33]	-8	hSpCas9	negative selection	6721290
31217008	31217031	16	+	27260156	HS294T	viability	GGCCTCGCGCTTCGTTCCCATGG	PYDC1	ENSG00000169900	0.0326966124676864	[265]	[64,105,129,126]	0	hSpCas9	negative selection	6721291
31216818	31216841	16	-	27260156	HS294T	viability	CTACGCAGCCGAGCTCGTCGTGG	PYDC1	ENSG00000169900	0.548513320223223	[527]	[150,181,493,401]	7	hSpCas9	negative selection	6721292
31216791	31216814	16	-	27260156	HCC44	viability	GCTGCGCGACATGCGCATGTTGG	PYDC1	ENSG00000169900	0.4194541467137346	[659]	[1141,784,926,1156]	7	hSpCas9	negative selection	6778283
31216795	31216818	16	+	27260156	HCC44	viability	CATGCGCATGTCGCGCAGCACGG	PYDC1	ENSG00000169900	0.559633556232666	[237]	[405,321,467,410]	8	hSpCas9	negative selection	6778284
31216831	31216854	16	+	27260156	HCC44	viability	GGCTGCGTAGTCCTCGTAGTAGG	PYDC1	ENSG00000169900	0.3840205333862043	[632]	[1223,748,1063,772]	6	hSpCas9	negative selection	6778285
31216878	31216901	16	-	27260156	HCC44	viability	GCTCGGGCAGCTAGATATCGTGG	PYDC1	ENSG00000169900	-0.04364678577985592	[138]	[183,79,210,156]	0	hSpCas9	negative selection	6842541
31217008	31217031	16	+	27260156	HCC44	viability	GGCCTCGCGCTTCGTTCCCATGG	PYDC1	ENSG00000169900	0.4012815916072658	[265]	[242,359,595,411]	6	hSpCas9	negative selection	6842542
31216818	31216841	16	-	27260156	HCC44	viability	CTACGCAGCCGAGCTCGTCGTGG	PYDC1	ENSG00000169900	0.19319948134626727	[527]	[557,756,684,702]	3	hSpCas9	negative selection	6842543
31216791	31216814	16	-	27260156	G402	viability	GCTGCGCGACATGCGCATGTTGG	PYDC1	ENSG00000169900	0.2607909082434908	[659]	[898,998,872,1071]	3	hSpCas9	negative selection	6899534
31216795	31216818	16	+	27260156	G402	viability	CATGCGCATGTCGCGCAGCACGG	PYDC1	ENSG00000169900	0.6138809743065472	[237]	[442,551,595,202]	7	hSpCas9	negative selection	6899535
31216831	31216854	16	+	27260156	G402	viability	GGCTGCGTAGTCCTCGTAGTAGG	PYDC1	ENSG00000169900	0.13592446126564456	[632]	[822,1011,1046,530]	1	hSpCas9	negative selection	6899536
31216878	31216901	16	-	27260156	G402	viability	GCTCGGGCAGCTAGATATCGTGG	PYDC1	ENSG00000169900	0.01999626293228851	[138]	[25,117,155,353]	0	hSpCas9	negative selection	6963792
31217008	31217031	16	+	27260156	G402	viability	GGCCTCGCGCTTCGTTCCCATGG	PYDC1	ENSG00000169900	0.22135299593413327	[265]	[309,489,314,392]	2	hSpCas9	negative selection	6963793
31216818	31216841	16	-	27260156	G402	viability	CTACGCAGCCGAGCTCGTCGTGG	PYDC1	ENSG00000169900	-0.19000566415306788	[527]	[509,527,880,338]	-2	hSpCas9	negative selection	6963794
31216791	31216814	16	-	27260156	L33	viability	GCTGCGCGACATGCGCATGTTGG	PYDC1	ENSG00000169900	0.19868336969434075	[659]	[830,279,449,796]	4	hSpCas9	negative selection	7020785
31216795	31216818	16	+	27260156	L33	viability	CATGCGCATGTCGCGCAGCACGG	PYDC1	ENSG00000169900	-0.20436987289837139	[237]	[187,76,123,252]	-5	hSpCas9	negative selection	7020786
31216831	31216854	16	+	27260156	L33	viability	GGCTGCGTAGTCCTCGTAGTAGG	PYDC1	ENSG00000169900	0.28425662480761676	[632]	[722,279,546,807]	6	hSpCas9	negative selection	7020787
31216878	31216901	16	-	27260156	L33	viability	GCTCGGGCAGCTAGATATCGTGG	PYDC1	ENSG00000169900	-0.913602256332456	[138]	[62,38,47,60]	-9	hSpCas9	negative selection	7085043
31217008	31217031	16	+	27260156	L33	viability	GGCCTCGCGCTTCGTTCCCATGG	PYDC1	ENSG00000169900	-0.1807358838609202	[265]	[259,72,193,191]	-4	hSpCas9	negative selection	7085044
31216818	31216841	16	-	27260156	L33	viability	CTACGCAGCCGAGCTCGTCGTGG	PYDC1	ENSG00000169900	-0.11133542844652419	[527]	[374,198,323,580]	-3	hSpCas9	negative selection	7085045
31216791	31216814	16	-	27260156	K562	viability	GCTGCGCGACATGCGCATGTTGG	PYDC1	ENSG00000169900	0.7182781605070353	[659]	[910,1402,769,803]	8	hSpCas9	negative selection	7142036
31216795	31216818	16	+	27260156	K562	viability	CATGCGCATGTCGCGCAGCACGG	PYDC1	ENSG00000169900	0.16746537658063843	[237]	[457,121,181,201]	2	hSpCas9	negative selection	7142037
31216831	31216854	16	+	27260156	K562	viability	GGCTGCGTAGTCCTCGTAGTAGG	PYDC1	ENSG00000169900	0.15101252150751915	[632]	[656,534,831,482]	1	hSpCas9	negative selection	7142038
31216878	31216901	16	-	27260156	K562	viability	GCTCGGGCAGCTAGATATCGTGG	PYDC1	ENSG00000169900	-1.6355176368072921	[138]	[62,30,34,31]	-9	hSpCas9	negative selection	7206294
31217008	31217031	16	+	27260156	K562	viability	GGCCTCGCGCTTCGTTCCCATGG	PYDC1	ENSG00000169900	0.01841269529607381	[265]	[315,424,147,98]	0	hSpCas9	negative selection	7206295
31216818	31216841	16	-	27260156	K562	viability	CTACGCAGCCGAGCTCGTCGTGG	PYDC1	ENSG00000169900	-0.310303881460966	[527]	[283,511,313,396]	-4	hSpCas9	negative selection	7206296
31216791	31216814	16	-	27260156	HT29	viability	GCTGCGCGACATGCGCATGTTGG	PYDC1	ENSG00000169900	0.11863419957838095	[659]	[1078,1109,755,602]	2	hSpCas9	negative selection	7263287
31216795	31216818	16	+	27260156	HT29	viability	CATGCGCATGTCGCGCAGCACGG	PYDC1	ENSG00000169900	0.1767907825777959	[237]	[341,398,378,207]	3	hSpCas9	negative selection	7263288
31216831	31216854	16	+	27260156	HT29	viability	GGCTGCGTAGTCCTCGTAGTAGG	PYDC1	ENSG00000169900	0.12204130765837712	[632]	[991,975,693,719]	2	hSpCas9	negative selection	7263289
31216878	31216901	16	-	27260156	HT29	viability	GCTCGGGCAGCTAGATATCGTGG	PYDC1	ENSG00000169900	-0.4900518392005433	[138]	[98,122,181,79]	-7	hSpCas9	negative selection	7327545
31217008	31217031	16	+	27260156	HT29	viability	GGCCTCGCGCTTCGTTCCCATGG	PYDC1	ENSG00000169900	0.3886327682849863	[265]	[574,325,606,211]	7	hSpCas9	negative selection	7327546
31216818	31216841	16	-	27260156	HT29	viability	CTACGCAGCCGAGCTCGTCGTGG	PYDC1	ENSG00000169900	0.026405458558079742	[527]	[590,593,661,741]	0	hSpCas9	negative selection	7327547
31216791	31216814	16	-	27260156	MHHES1	viability	GCTGCGCGACATGCGCATGTTGG	PYDC1	ENSG00000169900	0.1054903698140035	[659]	[805,875,786,734]	2	hSpCas9	negative selection	7384538
31216795	31216818	16	+	27260156	MHHES1	viability	CATGCGCATGTCGCGCAGCACGG	PYDC1	ENSG00000169900	-0.05488245168614192	[237]	[239,417,227,173]	-1	hSpCas9	negative selection	7384539
31216831	31216854	16	+	27260156	MHHES1	viability	GGCTGCGTAGTCCTCGTAGTAGG	PYDC1	ENSG00000169900	0.027165468930667958	[632]	[851,733,788,567]	0	hSpCas9	negative selection	7384540
31216878	31216901	16	-	27260156	MHHES1	viability	GCTCGGGCAGCTAGATATCGTGG	PYDC1	ENSG00000169900	-0.8216923472165087	[138]	[74,62,155,60]	-9	hSpCas9	negative selection	7448796
31217008	31217031	16	+	27260156	MHHES1	viability	GGCCTCGCGCTTCGTTCCCATGG	PYDC1	ENSG00000169900	0.3032080948921332	[265]	[277,552,372,291]	5	hSpCas9	negative selection	7448797
31216818	31216841	16	-	27260156	MHHES1	viability	CTACGCAGCCGAGCTCGTCGTGG	PYDC1	ENSG00000169900	-0.15270291714017908	[527]	[657,774,442,336]	-3	hSpCas9	negative selection	7448798
31216791	31216814	16	-	27260156	MEWO	viability	GCTGCGCGACATGCGCATGTTGG	PYDC1	ENSG00000169900	-0.047994242042416146	[659]	[715,529,568]	-1	hSpCas9	negative selection	7505789
31216795	31216818	16	+	27260156	MEWO	viability	CATGCGCATGTCGCGCAGCACGG	PYDC1	ENSG00000169900	-0.14972888977929388	[237]	[266,187,159]	-3	hSpCas9	negative selection	7505790
31216831	31216854	16	+	27260156	MEWO	viability	GGCTGCGTAGTCCTCGTAGTAGG	PYDC1	ENSG00000169900	0.09026382147399342	[632]	[758,651,504]	2	hSpCas9	negative selection	7505791
31216878	31216901	16	-	27260156	MEWO	viability	GCTCGGGCAGCTAGATATCGTGG	PYDC1	ENSG00000169900	0.34250216852302695	[138]	[232,128,145]	7	hSpCas9	negative selection	7570047
31217008	31217031	16	+	27260156	MEWO	viability	GGCCTCGCGCTTCGTTCCCATGG	PYDC1	ENSG00000169900	0.46611796808716277	[265]	[299,293,428]	8	hSpCas9	negative selection	7570048
31216818	31216841	16	-	27260156	MEWO	viability	CTACGCAGCCGAGCTCGTCGTGG	PYDC1	ENSG00000169900	-0.1650297752420647	[527]	[505,301,526]	-4	hSpCas9	negative selection	7570049
31216791	31216814	16	-	27260156	LNCAPCLONEFGC	viability	GCTGCGCGACATGCGCATGTTGG	PYDC1	ENSG00000169900	0.5682277309118354	[659]	[898,836,1113,731]	8	hSpCas9	negative selection	7627040
31216795	31216818	16	+	27260156	LNCAPCLONEFGC	viability	CATGCGCATGTCGCGCAGCACGG	PYDC1	ENSG00000169900	0.06136434077523201	[237]	[267,173,182,270]	0	hSpCas9	negative selection	7627041
31216831	31216854	16	+	27260156	LNCAPCLONEFGC	viability	GGCTGCGTAGTCCTCGTAGTAGG	PYDC1	ENSG00000169900	0.34414371362263024	[632]	[743,713,817,648]	5	hSpCas9	negative selection	7627042
31216878	31216901	16	-	27260156	LNCAPCLONEFGC	viability	GCTCGGGCAGCTAGATATCGTGG	PYDC1	ENSG00000169900	-0.5272866759634194	[138]	[83,68,75,119]	-7	hSpCas9	negative selection	7691298
31217008	31217031	16	+	27260156	LNCAPCLONEFGC	viability	GGCCTCGCGCTTCGTTCCCATGG	PYDC1	ENSG00000169900	0.2585474318423946	[265]	[291,218,366,290]	4	hSpCas9	negative selection	7691299
31216818	31216841	16	-	27260156	LNCAPCLONEFGC	viability	CTACGCAGCCGAGCTCGTCGTGG	PYDC1	ENSG00000169900	0.09361328227358853	[527]	[508,402,663,494]	1	hSpCas9	negative selection	7691300
31216791	31216814	16	-	27260156	PANC0327	viability	GCTGCGCGACATGCGCATGTTGG	PYDC1	ENSG00000169900	0.6330897814204867	[659]	[1007,764,729,1159]	8	hSpCas9	negative selection	7748291
31216795	31216818	16	+	27260156	PANC0327	viability	CATGCGCATGTCGCGCAGCACGG	PYDC1	ENSG00000169900	0.7584025206740466	[237]	[446,317,395,281]	9	hSpCas9	negative selection	7748292
31216831	31216854	16	+	27260156	PANC0327	viability	GGCTGCGTAGTCCTCGTAGTAGG	PYDC1	ENSG00000169900	0.19939264950379326	[632]	[615,422,860,708]	3	hSpCas9	negative selection	7748293
31216878	31216901	16	-	27260156	PANC0327	viability	GCTCGGGCAGCTAGATATCGTGG	PYDC1	ENSG00000169900	-0.30923004218542505	[138]	[98,203,41,39]	-4	hSpCas9	negative selection	7812549
31217008	31217031	16	+	27260156	PANC0327	viability	GGCCTCGCGCTTCGTTCCCATGG	PYDC1	ENSG00000169900	-0.45235378441180496	[265]	[163,180,200,142]	-6	hSpCas9	negative selection	7812550
31216818	31216841	16	-	27260156	PANC0327	viability	CTACGCAGCCGAGCTCGTCGTGG	PYDC1	ENSG00000169900	0.07312364513224151	[527]	[697,272,624,422]	1	hSpCas9	negative selection	7812551
31216791	31216814	16	-	27260156	NCIH2009	viability	GCTGCGCGACATGCGCATGTTGG	PYDC1	ENSG00000169900	0.47051767292830726	[659]	[1758,1115,1053]	6	hSpCas9	negative selection	7869542
31216795	31216818	16	+	27260156	NCIH2009	viability	CATGCGCATGTCGCGCAGCACGG	PYDC1	ENSG00000169900	0.5079526282119493	[237]	[556,439,437]	7	hSpCas9	negative selection	7869543
31216831	31216854	16	+	27260156	NCIH2009	viability	GGCTGCGTAGTCCTCGTAGTAGG	PYDC1	ENSG00000169900	0.3674455121465973	[632]	[1173,1052,1201]	5	hSpCas9	negative selection	7869544
31216878	31216901	16	-	27260156	NCIH2009	viability	GCTCGGGCAGCTAGATATCGTGG	PYDC1	ENSG00000169900	-0.33149954235849566	[138]	[182,121,163]	-4	hSpCas9	negative selection	7933800
31217008	31217031	16	+	27260156	NCIH2009	viability	GGCCTCGCGCTTCGTTCCCATGG	PYDC1	ENSG00000169900	0.08230583332522001	[265]	[445,288,456]	1	hSpCas9	negative selection	7933801
31216818	31216841	16	-	27260156	NCIH2009	viability	CTACGCAGCCGAGCTCGTCGTGG	PYDC1	ENSG00000169900	0.21791217252370151	[527]	[747,898,902]	3	hSpCas9	negative selection	7933802
31216791	31216814	16	-	27260156	NCIH1373	viability	GCTGCGCGACATGCGCATGTTGG	PYDC1	ENSG00000169900	0.7579424506578393	[659]	[1519,1287,1015,318]	7	hSpCas9	negative selection	7990793
31216795	31216818	16	+	27260156	NCIH1373	viability	CATGCGCATGTCGCGCAGCACGG	PYDC1	ENSG00000169900	0.10288643164079991	[237]	[162,401,160,103]	1	hSpCas9	negative selection	7990794
31216831	31216854	16	+	27260156	NCIH1373	viability	GGCTGCGTAGTCCTCGTAGTAGG	PYDC1	ENSG00000169900	0.2204527014554512	[632]	[833,647,814,272]	2	hSpCas9	negative selection	7990795
31216878	31216901	16	-	27260156	NCIH1373	viability	GCTCGGGCAGCTAGATATCGTGG	PYDC1	ENSG00000169900	-0.9712309769272649	[138]	[143,105,55,3]	-7	hSpCas9	negative selection	8055051
31217008	31217031	16	+	27260156	NCIH1373	viability	GGCCTCGCGCTTCGTTCCCATGG	PYDC1	ENSG00000169900	0.10769060894073001	[265]	[265,331,291,101]	1	hSpCas9	negative selection	8055052
31216818	31216841	16	-	27260156	NCIH1373	viability	CTACGCAGCCGAGCTCGTCGTGG	PYDC1	ENSG00000169900	0.602061989180161	[527]	[439,627,1572,233]	6	hSpCas9	negative selection	8055053
31216791	31216814	16	-	27260156	PATU8902	viability	GCTGCGCGACATGCGCATGTTGG	PYDC1	ENSG00000169900	0.7707348368032855	[659]	[1044,1099,2051,1993]	7	hSpCas9	negative selection	8112044
31216795	31216818	16	+	27260156	PATU8902	viability	CATGCGCATGTCGCGCAGCACGG	PYDC1	ENSG00000169900	0.1785017643710003	[237]	[275,126,441,670]	1	hSpCas9	negative selection	8112045
31216831	31216854	16	+	27260156	PATU8902	viability	GGCTGCGTAGTCCTCGTAGTAGG	PYDC1	ENSG00000169900	-0.006440126670940294	[632]	[1129,921,616,901]	0	hSpCas9	negative selection	8112046
31216878	31216901	16	-	27260156	PATU8902	viability	GCTCGGGCAGCTAGATATCGTGG	PYDC1	ENSG00000169900	-0.610428191143775	[138]	[55,74,257,77]	-5	hSpCas9	negative selection	8176302
31217008	31217031	16	+	27260156	PATU8902	viability	GGCCTCGCGCTTCGTTCCCATGG	PYDC1	ENSG00000169900	0.24441733323606696	[265]	[240,559,225,829]	2	hSpCas9	negative selection	8176303
31216818	31216841	16	-	27260156	PATU8902	viability	CTACGCAGCCGAGCTCGTCGTGG	PYDC1	ENSG00000169900	0.3050524761053015	[527]	[562,970,649,1596]	3	hSpCas9	negative selection	8176304
31216791	31216814	16	-	27260156	PANC1	viability	GCTGCGCGACATGCGCATGTTGG	PYDC1	ENSG00000169900	0.29716724825283347	[659]	[403,997,1000,478]	5	hSpCas9	negative selection	8233295
31216795	31216818	16	+	27260156	PANC1	viability	CATGCGCATGTCGCGCAGCACGG	PYDC1	ENSG00000169900	0.38185307129743307	[237]	[226,397,161,295]	6	hSpCas9	negative selection	8233296
31216831	31216854	16	+	27260156	PANC1	viability	GGCTGCGTAGTCCTCGTAGTAGG	PYDC1	ENSG00000169900	0.10322351560441217	[632]	[513,733,518,589]	1	hSpCas9	negative selection	8233297
31216878	31216901	16	-	27260156	PANC1	viability	GCTCGGGCAGCTAGATATCGTGG	PYDC1	ENSG00000169900	0.034691565421898884	[138]	[105,99,133,139]	0	hSpCas9	negative selection	8297553
31217008	31217031	16	+	27260156	PANC1	viability	GGCCTCGCGCTTCGTTCCCATGG	PYDC1	ENSG00000169900	0.2801717898806868	[265]	[236,258,344,263]	4	hSpCas9	negative selection	8297554
31216818	31216841	16	-	27260156	PANC1	viability	CTACGCAGCCGAGCTCGTCGTGG	PYDC1	ENSG00000169900	0.19178009019498035	[527]	[447,562,543,518]	3	hSpCas9	negative selection	8297555
31216791	31216814	16	-	27260156	PANC0813	viability	GCTGCGCGACATGCGCATGTTGG	PYDC1	ENSG00000169900	0.5130101174917686	[659]	[1110,1377,1026,917]	7	hSpCas9	negative selection	8354546
31216795	31216818	16	+	27260156	PANC0813	viability	CATGCGCATGTCGCGCAGCACGG	PYDC1	ENSG00000169900	0.1502973890876349	[237]	[413,237,406,197]	2	hSpCas9	negative selection	8354547
31216831	31216854	16	+	27260156	PANC0813	viability	GGCTGCGTAGTCCTCGTAGTAGG	PYDC1	ENSG00000169900	0.3449043174973267	[632]	[1065,854,920,944]	5	hSpCas9	negative selection	8354548
31216878	31216901	16	-	27260156	PANC0813	viability	GCTCGGGCAGCTAGATATCGTGG	PYDC1	ENSG00000169900	-0.4983490821698562	[138]	[102,136,140,81]	-6	hSpCas9	negative selection	8418804
31217008	31217031	16	+	27260156	PANC0813	viability	GGCCTCGCGCTTCGTTCCCATGG	PYDC1	ENSG00000169900	0.4801698928085351	[265]	[258,499,587,382]	7	hSpCas9	negative selection	8418805
31216818	31216841	16	-	27260156	PANC0813	viability	CTACGCAGCCGAGCTCGTCGTGG	PYDC1	ENSG00000169900	0.30289556578855115	[527]	[527,599,782,1106]	5	hSpCas9	negative selection	8418806
31216791	31216814	16	-	27260156	RDES	viability	GCTGCGCGACATGCGCATGTTGG	PYDC1	ENSG00000169900	-0.14439069943581523	[659]	[630,607,826,682]	-2	hSpCas9	negative selection	8475797
31216795	31216818	16	+	27260156	RDES	viability	CATGCGCATGTCGCGCAGCACGG	PYDC1	ENSG00000169900	0.4361804091285595	[237]	[164,406,369,607]	7	hSpCas9	negative selection	8475798
31216831	31216854	16	+	27260156	RDES	viability	GGCTGCGTAGTCCTCGTAGTAGG	PYDC1	ENSG00000169900	-0.009201844120792668	[632]	[625,637,747,918]	0	hSpCas9	negative selection	8475799
31216878	31216901	16	-	27260156	RDES	viability	GCTCGGGCAGCTAGATATCGTGG	PYDC1	ENSG00000169900	-0.36403575842847125	[138]	[106,64,135,207]	-6	hSpCas9	negative selection	8540055
31217008	31217031	16	+	27260156	RDES	viability	GGCCTCGCGCTTCGTTCCCATGG	PYDC1	ENSG00000169900	-0.14429270404200245	[265]	[245,319,260,271]	-2	hSpCas9	negative selection	8540056
31216818	31216841	16	-	27260156	RDES	viability	CTACGCAGCCGAGCTCGTCGTGG	PYDC1	ENSG00000169900	-0.09358408276152302	[527]	[538,506,579,657]	-1	hSpCas9	negative selection	8540057
31216791	31216814	16	-	27260156	PC3	viability	GCTGCGCGACATGCGCATGTTGG	PYDC1	ENSG00000169900	0.3648027308618028	[659]	[467,1019,1513,721]	7	hSpCas9	negative selection	8597048
31216795	31216818	16	+	27260156	PC3	viability	CATGCGCATGTCGCGCAGCACGG	PYDC1	ENSG00000169900	-0.007184224857597177	[237]	[125,294,398,210]	0	hSpCas9	negative selection	8597049
31216831	31216854	16	+	27260156	PC3	viability	GGCTGCGTAGTCCTCGTAGTAGG	PYDC1	ENSG00000169900	0.2987895260527333	[632]	[585,747,1117,780]	6	hSpCas9	negative selection	8597050
31216878	31216901	16	-	27260156	PC3	viability	GCTCGGGCAGCTAGATATCGTGG	PYDC1	ENSG00000169900	-0.0949004195574914	[138]	[71,49,288,191]	-2	hSpCas9	negative selection	8661306
31217008	31217031	16	+	27260156	PC3	viability	GGCCTCGCGCTTCGTTCCCATGG	PYDC1	ENSG00000169900	0.08253182398315817	[265]	[176,279,491,273]	1	hSpCas9	negative selection	8661307
31216818	31216841	16	-	27260156	PC3	viability	CTACGCAGCCGAGCTCGTCGTGG	PYDC1	ENSG00000169900	0.099355517369034	[527]	[357,642,849,543]	2	hSpCas9	negative selection	8661308
31216791	31216814	16	-	27260156	PATU8988T	viability	GCTGCGCGACATGCGCATGTTGG	PYDC1	ENSG00000169900	0.2924441636243219	[659]	[650,754,605,1140]	5	hSpCas9	negative selection	8718299
31216795	31216818	16	+	27260156	PATU8988T	viability	CATGCGCATGTCGCGCAGCACGG	PYDC1	ENSG00000169900	0.09734703423583368	[237]	[291,104,343,226]	1	hSpCas9	negative selection	8718300
31216831	31216854	16	+	27260156	PATU8988T	viability	GGCTGCGTAGTCCTCGTAGTAGG	PYDC1	ENSG00000169900	0.3031464763055837	[632]	[541,823,775,893]	5	hSpCas9	negative selection	8718301
31216878	31216901	16	-	27260156	PATU8988T	viability	GCTCGGGCAGCTAGATATCGTGG	PYDC1	ENSG00000169900	-0.8099202609857319	[138]	[94,128,62,19]	-8	hSpCas9	negative selection	8782557
31217008	31217031	16	+	27260156	PATU8988T	viability	GGCCTCGCGCTTCGTTCCCATGG	PYDC1	ENSG00000169900	0.7561992162709852	[265]	[391,445,495,399]	9	hSpCas9	negative selection	8782558
31216818	31216841	16	-	27260156	PATU8988T	viability	CTACGCAGCCGAGCTCGTCGTGG	PYDC1	ENSG00000169900	-0.14063549811471268	[527]	[569,531,431,311]	-2	hSpCas9	negative selection	8782559
31216791	31216814	16	-	27260156	T47D	viability	GCTGCGCGACATGCGCATGTTGG	PYDC1	ENSG00000169900	0.05647439432902135	[659]	[857,728,800,816]	1	hSpCas9	negative selection	8839550
31216795	31216818	16	+	27260156	T47D	viability	CATGCGCATGTCGCGCAGCACGG	PYDC1	ENSG00000169900	0.12944076926210035	[237]	[322,296,247,347]	2	hSpCas9	negative selection	8839551
31216831	31216854	16	+	27260156	T47D	viability	GGCTGCGTAGTCCTCGTAGTAGG	PYDC1	ENSG00000169900	0.09581622826537556	[632]	[706,798,787,858]	2	hSpCas9	negative selection	8839552
31216878	31216901	16	-	27260156	T47D	viability	GCTCGGGCAGCTAGATATCGTGG	PYDC1	ENSG00000169900	-0.29398986666350324	[138]	[122,104,108,195]	-6	hSpCas9	negative selection	8903808
31217008	31217031	16	+	27260156	T47D	viability	GGCCTCGCGCTTCGTTCCCATGG	PYDC1	ENSG00000169900	0.1607161980353765	[265]	[317,356,386,320]	3	hSpCas9	negative selection	8903809
31216818	31216841	16	-	27260156	T47D	viability	CTACGCAGCCGAGCTCGTCGTGG	PYDC1	ENSG00000169900	-0.02486607735759097	[527]	[551,522,720,627]	0	hSpCas9	negative selection	8903810
31216791	31216814	16	-	27260156	SU8686	viability	GCTGCGCGACATGCGCATGTTGG	PYDC1	ENSG00000169900	0.34901323296654585	[659]	[718,749,940,965]	6	hSpCas9	negative selection	8960801
31216795	31216818	16	+	27260156	SU8686	viability	CATGCGCATGTCGCGCAGCACGG	PYDC1	ENSG00000169900	0.12647137090615268	[237]	[193,284,222,342]	2	hSpCas9	negative selection	8960802
31216831	31216854	16	+	27260156	SU8686	viability	GGCTGCGTAGTCCTCGTAGTAGG	PYDC1	ENSG00000169900	0.1725867208187551	[632]	[574,632,711,971]	3	hSpCas9	negative selection	8960803
31216878	31216901	16	-	27260156	SU8686	viability	GCTCGGGCAGCTAGATATCGTGG	PYDC1	ENSG00000169900	-0.4214815192389396	[138]	[144,95,53,111]	-6	hSpCas9	negative selection	9025059
31217008	31217031	16	+	27260156	SU8686	viability	GGCCTCGCGCTTCGTTCCCATGG	PYDC1	ENSG00000169900	0.10349185861659904	[265]	[221,297,282,342]	1	hSpCas9	negative selection	9025060
31216818	31216841	16	-	27260156	SU8686	viability	CTACGCAGCCGAGCTCGTCGTGG	PYDC1	ENSG00000169900	0.039488866558115315	[527]	[458,417,539,797]	0	hSpCas9	negative selection	9025061
31216791	31216814	16	-	27260156	SKES1	viability	GCTGCGCGACATGCGCATGTTGG	PYDC1	ENSG00000169900	0.10692240865305758	[659]	[738,824,674,618]	2	hSpCas9	negative selection	9082052
31216795	31216818	16	+	27260156	SKES1	viability	CATGCGCATGTCGCGCAGCACGG	PYDC1	ENSG00000169900	0.5503610422318492	[237]	[501,293,205,395]	9	hSpCas9	negative selection	9082053
31216831	31216854	16	+	27260156	SKES1	viability	GGCTGCGTAGTCCTCGTAGTAGG	PYDC1	ENSG00000169900	0.1588282431099271	[632]	[603,973,698,569]	3	hSpCas9	negative selection	9082054
31216878	31216901	16	-	27260156	SKES1	viability	GCTCGGGCAGCTAGATATCGTGG	PYDC1	ENSG00000169900	-0.5722641722019903	[138]	[100,67,108,91]	-8	hSpCas9	negative selection	9146310
31217008	31217031	16	+	27260156	SKES1	viability	GGCCTCGCGCTTCGTTCCCATGG	PYDC1	ENSG00000169900	0.41958508661558025	[265]	[348,502,304,284]	8	hSpCas9	negative selection	9146311
31216818	31216841	16	-	27260156	SKES1	viability	CTACGCAGCCGAGCTCGTCGTGG	PYDC1	ENSG00000169900	0.15746225203938943	[527]	[900,574,470,455]	3	hSpCas9	negative selection	9146312
31216791	31216814	16	-	27260156	TOV112D	viability	GCTGCGCGACATGCGCATGTTGG	PYDC1	ENSG00000169900	0.1718876713698585	[659]	[919,1001,623,515]	3	hSpCas9	negative selection	9203303
31216795	31216818	16	+	27260156	TOV112D	viability	CATGCGCATGTCGCGCAGCACGG	PYDC1	ENSG00000169900	-0.15041803833753042	[237]	[278,166,141,262]	-3	hSpCas9	negative selection	9203304
31216831	31216854	16	+	27260156	TOV112D	viability	GGCTGCGTAGTCCTCGTAGTAGG	PYDC1	ENSG00000169900	0.15876074025075299	[632]	[825,1171,466,494]	3	hSpCas9	negative selection	9203305
31216878	31216901	16	-	27260156	TOV112D	viability	GCTCGGGCAGCTAGATATCGTGG	PYDC1	ENSG00000169900	-0.526280595124472	[138]	[69,220,68,55]	-8	hSpCas9	negative selection	9267561
31217008	31217031	16	+	27260156	TOV112D	viability	GGCCTCGCGCTTCGTTCCCATGG	PYDC1	ENSG00000169900	-0.17992627685779528	[265]	[223,316,164,252]	-4	hSpCas9	negative selection	9267562
31216818	31216841	16	-	27260156	TOV112D	viability	CTACGCAGCCGAGCTCGTCGTGG	PYDC1	ENSG00000169900	0.14997807122673443	[527]	[246,857,685,592]	3	hSpCas9	negative selection	9267563
31216791	31216814	16	-	27260156	TC71	viability	GCTGCGCGACATGCGCATGTTGG	PYDC1	ENSG00000169900	0.1487896914591661	[659]	[757,820,736,825]	4	hSpCas9	negative selection	9324554
31216795	31216818	16	+	27260156	TC71	viability	CATGCGCATGTCGCGCAGCACGG	PYDC1	ENSG00000169900	0.21898526358763326	[237]	[255,291,313,327]	5	hSpCas9	negative selection	9324555
31216831	31216854	16	+	27260156	TC71	viability	GGCTGCGTAGTCCTCGTAGTAGG	PYDC1	ENSG00000169900	-0.09184423268939734	[632]	[639,537,694,673]	-2	hSpCas9	negative selection	9324556
31216878	31216901	16	-	27260156	TC71	viability	GCTCGGGCAGCTAGATATCGTGG	PYDC1	ENSG00000169900	-0.49489324356685427	[138]	[123,80,74,145]	-8	hSpCas9	negative selection	9388812
31217008	31217031	16	+	27260156	TC71	viability	GGCCTCGCGCTTCGTTCCCATGG	PYDC1	ENSG00000169900	0.06021914029101727	[265]	[306,336,273,269]	1	hSpCas9	negative selection	9388813
31216818	31216841	16	-	27260156	TC71	viability	CTACGCAGCCGAGCTCGTCGTGG	PYDC1	ENSG00000169900	-0.33767648872475553	[527]	[436,481,389,486]	-7	hSpCas9	negative selection	9388814
31216791	31216814	16	-	27260156	TC32	viability	GCTGCGCGACATGCGCATGTTGG	PYDC1	ENSG00000169900	0.16453957345510384	[659]	[808,520,844,635]	3	hSpCas9	negative selection	9445805
31216795	31216818	16	+	27260156	TC32	viability	CATGCGCATGTCGCGCAGCACGG	PYDC1	ENSG00000169900	0.38438696626612334	[237]	[343,130,486,276]	6	hSpCas9	negative selection	9445806
31216831	31216854	16	+	27260156	TC32	viability	GGCTGCGTAGTCCTCGTAGTAGG	PYDC1	ENSG00000169900	-0.046784017621529894	[632]	[556,377,831,627]	-1	hSpCas9	negative selection	9445807
31216878	31216901	16	-	27260156	TC32	viability	GCTCGGGCAGCTAGATATCGTGG	PYDC1	ENSG00000169900	0.03328574139974494	[138]	[91,142,202,99]	0	hSpCas9	negative selection	9510063
31217008	31217031	16	+	27260156	TC32	viability	GGCCTCGCGCTTCGTTCCCATGG	PYDC1	ENSG00000169900	-0.28093283102036526	[265]	[245,129,294,176]	-5	hSpCas9	negative selection	9510064
31216818	31216841	16	-	27260156	TC32	viability	CTACGCAGCCGAGCTCGTCGTGG	PYDC1	ENSG00000169900	-0.27246251234189944	[527]	[354,264,532,558]	-5	hSpCas9	negative selection	9510065
31216777	31216800	16	-	27869803	HPAFII	viability after 27 days	GCATGTTGGAGGAGGCCGCACGG	PYDC1	ENSG00000169900	-0.8946405148741562	[234]	[108,30,NaN]	-6	hSpCas9	negative selection	9556911
31216905	31216928	16	-	27869803	HPAFII	viability after 27 days	GGGCTTTGAGCGCATCCCGCGGG	PYDC1	ENSG00000169900	0.6061897761609327	[121]	[191,18,NaN]	5	hSpCas9	negative selection	9556912
31217008	31217031	16	+	27869803	HPAFII	viability after 27 days	GGCCTCGCGCTTCGTTCCCATGG	PYDC1	ENSG00000169900	0.49526496366502415	[111]	[172,7,NaN]	4	hSpCas9	negative selection	9556913
31217010	31217033	16	-	27869803	HPAFII	viability after 27 days	AGCCATGGGAACGAAGCGCGAGG	PYDC1	ENSG00000169900	1.4392717584482702	[204]	[288,294,NaN]	9	hSpCas9	negative selection	9556914
31216777	31216800	16	-	27869803	HPAFII	viability after 15 days	GCATGTTGGAGGAGGCCGCACGG	PYDC1	ENSG00000169900	-0.5944078630313693	[234]	[260,108,NaN]	-6	hSpCas9	negative selection	9639360
31216905	31216928	16	-	27869803	HPAFII	viability after 15 days	GGGCTTTGAGCGCATCCCGCGGG	PYDC1	ENSG00000169900	0.8079607733113073	[121]	[416,112,NaN]	8	hSpCas9	negative selection	9639361
31217008	31217031	16	+	27869803	HPAFII	viability after 15 days	GGCCTCGCGCTTCGTTCCCATGG	PYDC1	ENSG00000169900	-0.7359625991452616	[111]	[128,36,NaN]	-7	hSpCas9	negative selection	9639362
31217010	31217033	16	-	27869803	HPAFII	viability after 15 days	AGCCATGGGAACGAAGCGCGAGG	PYDC1	ENSG00000169900	1.0321325863495496	[204]	[592,361,NaN]	9	hSpCas9	negative selection	9639363
31216777	31216800	16	-	27869803	ASPC1	viability after 36 days	GCATGTTGGAGGAGGCCGCACGG	PYDC1	ENSG00000169900	0.05430303276240889	[404]	[211,154,92]	0	hSpCas9	negative selection	9721809
31216905	31216928	16	-	27869803	ASPC1	viability after 36 days	GGGCTTTGAGCGCATCCCGCGGG	PYDC1	ENSG00000169900	-0.058463077605362734	[214]	[44,45,110]	0	hSpCas9	negative selection	9721810
31217008	31217031	16	+	27869803	ASPC1	viability after 36 days	GGCCTCGCGCTTCGTTCCCATGG	PYDC1	ENSG00000169900	0.11829374046470464	[178]	[110,54,46]	1	hSpCas9	negative selection	9721811
31217010	31217033	16	-	27869803	ASPC1	viability after 36 days	AGCCATGGGAACGAAGCGCGAGG	PYDC1	ENSG00000169900	1.223721658831313	[473]	[274,143,652]	9	hSpCas9	negative selection	9721812
31216777	31216800	16	-	27869803	PATU8988S	viability after 35 days	GCATGTTGGAGGAGGCCGCACGG	PYDC1	ENSG00000169900	-0.12576912678908025	[385]	[134,149,NaN]	-1	hSpCas9	negative selection	9804258
31216905	31216928	16	-	27869803	PATU8988S	viability after 35 days	GGGCTTTGAGCGCATCCCGCGGG	PYDC1	ENSG00000169900	-0.7280300174807124	[268]	[24,105,NaN]	-6	hSpCas9	negative selection	9804259
31217008	31217031	16	+	27869803	PATU8988S	viability after 35 days	GGCCTCGCGCTTCGTTCCCATGG	PYDC1	ENSG00000169900	0.6265945148332012	[205]	[168,86,NaN]	7	hSpCas9	negative selection	9804260
31217010	31217033	16	-	27869803	PATU8988S	viability after 35 days	AGCCATGGGAACGAAGCGCGAGG	PYDC1	ENSG00000169900	0.24048443082840393	[492]	[265,202,NaN]	2	hSpCas9	negative selection	9804261
31216777	31216800	16	-	27869803	PATU8988S	viability after 31 days	GCATGTTGGAGGAGGCCGCACGG	PYDC1	ENSG00000169900	-0.03307679432753585	[385]	[83,234,NaN]	0	hSpCas9	negative selection	9886707
31216905	31216928	16	-	27869803	PATU8988S	viability after 31 days	GGGCTTTGAGCGCATCCCGCGGG	PYDC1	ENSG00000169900	0.08522358374530536	[268]	[60,180,NaN]	1	hSpCas9	negative selection	9886708
31217008	31217031	16	+	27869803	PATU8988S	viability after 31 days	GGCCTCGCGCTTCGTTCCCATGG	PYDC1	ENSG00000169900	0.789252947173641	[205]	[115,174,NaN]	8	hSpCas9	negative selection	9886709
31217010	31217033	16	-	27869803	PATU8988S	viability after 31 days	AGCCATGGGAACGAAGCGCGAGG	PYDC1	ENSG00000169900	0.4919164586043223	[492]	[341,192,NaN]	6	hSpCas9	negative selection	9886710
31216777	31216800	16	-	27869803	HPAFII	viability after 35 days	GCATGTTGGAGGAGGCCGCACGG	PYDC1	ENSG00000169900	-2.047699233176576	[234]	[48,5,NaN]	-7	hSpCas9	negative selection	9969156
31216905	31216928	16	-	27869803	HPAFII	viability after 35 days	GGGCTTTGAGCGCATCCCGCGGG	PYDC1	ENSG00000169900	1.0176828220489698	[121]	[220,16,NaN]	7	hSpCas9	negative selection	9969157
31217008	31217031	16	+	27869803	HPAFII	viability after 35 days	GGCCTCGCGCTTCGTTCCCATGG	PYDC1	ENSG00000169900	0.27771036843871044	[111]	[127,1,NaN]	1	hSpCas9	negative selection	9969158
31217010	31217033	16	-	27869803	HPAFII	viability after 35 days	AGCCATGGGAACGAAGCGCGAGG	PYDC1	ENSG00000169900	1.9915843340221215	[204]	[177,676,NaN]	9	hSpCas9	negative selection	9969159
31216777	31216800	16	-	27869803	HPAFII	viability after 31 days	GCATGTTGGAGGAGGCCGCACGG	PYDC1	ENSG00000169900	-1.3369704455981155	[234]	[67,34,NaN]	-7	hSpCas9	negative selection	10051605
31216905	31216928	16	-	27869803	HPAFII	viability after 31 days	GGGCTTTGAGCGCATCCCGCGGG	PYDC1	ENSG00000169900	0.7549181270704196	[121]	[216,4,NaN]	5	hSpCas9	negative selection	10051606
31217008	31217031	16	+	27869803	HPAFII	viability after 31 days	GGCCTCGCGCTTCGTTCCCATGG	PYDC1	ENSG00000169900	0.09686557523744632	[111]	[127,0,NaN]	0	hSpCas9	negative selection	10051607
31217010	31217033	16	-	27869803	HPAFII	viability after 31 days	AGCCATGGGAACGAAGCGCGAGG	PYDC1	ENSG00000169900	1.4884836364278269	[204]	[195,460,NaN]	9	hSpCas9	negative selection	10051608
31216998	31217021	16	-	28162770	P31FUJ	viability	GAAGCGCGAGGCCATCCTGAAGG	PYDC1	ENSG00000169900	0.1144687385874471	[315]	[401]	1	hSpCas9	negative selection	10220494
31216818	31216841	16	-	28162770	P31FUJ	viability	CTACGCAGCCGAGCTCGTCGTGG	PYDC1	ENSG00000169900	-0.2328022044143787	[71]	[71]	-2	hSpCas9	negative selection	10220495
31216987	31217010	16	+	28162770	P31FUJ	viability	GTTCTCCAGCACCTTCAGGATGG	PYDC1	ENSG00000169900	-0.05395412395045007	[393]	[445]	0	hSpCas9	negative selection	10220496
31216974	31216997	16	-	28162770	P31FUJ	viability	GCTGGAGAACCTGACACCGGAGG	PYDC1	ENSG00000169900	-0.9973722599751864	[298]	[175]	-6	hSpCas9	negative selection	10220497
31216941	31216964	16	-	28162770	P31FUJ	viability	GTTCAAGATGAAGCTGGGGACGG	PYDC1	ENSG00000169900	-0.2060021450706636	[159]	[162]	-2	hSpCas9	negative selection	10220498
31216906	31216929	16	-	28162770	P31FUJ	viability	AGGGCTTTGAGCGCATCCCGCGG	PYDC1	ENSG00000169900	-0.26825104041866843	[205]	[200]	-3	hSpCas9	negative selection	10220499
31216785	31216808	16	-	28162770	P31FUJ	viability	CGACATGCGCATGTTGGAGGAGG	PYDC1	ENSG00000169900	0.8352431830087201	[175]	[368]	8	hSpCas9	negative selection	10220500
31216768	31216791	16	-	28162770	P31FUJ	viability	AGGAGGCCGCACGGCTGCAGCGG	PYDC1	ENSG00000169900	0.30635660669365283	[191]	[278]	3	hSpCas9	negative selection	10220501
31217010	31217033	16	-	28162770	P31FUJ	viability	AGCCATGGGAACGAAGCGCGAGG	PYDC1	ENSG00000169900	0.28177096841537974	[13]	[19]	3	hSpCas9	negative selection	10220502
31216878	31216901	16	-	28162770	P31FUJ	viability	GCTCGGGCAGCTAGATATCGTGG	PYDC1	ENSG00000169900	0.39998882139739256	[177]	[275]	4	hSpCas9	negative selection	10220503
31216998	31217021	16	-	28162770	TF1	viability	GAAGCGCGAGGCCATCCTGAAGG	PYDC1	ENSG00000169900	NaN	[NaN]	[298]	1	hSpCas9	negative selection	10389860
31216818	31216841	16	-	28162770	TF1	viability	CTACGCAGCCGAGCTCGTCGTGG	PYDC1	ENSG00000169900	NaN	[NaN]	[40]	1	hSpCas9	negative selection	10389861
31216987	31217010	16	+	28162770	TF1	viability	GTTCTCCAGCACCTTCAGGATGG	PYDC1	ENSG00000169900	NaN	[NaN]	[358]	1	hSpCas9	negative selection	10389862
31216974	31216997	16	-	28162770	TF1	viability	GCTGGAGAACCTGACACCGGAGG	PYDC1	ENSG00000169900	NaN	[NaN]	[42]	1	hSpCas9	negative selection	10389863
31216941	31216964	16	-	28162770	TF1	viability	GTTCAAGATGAAGCTGGGGACGG	PYDC1	ENSG00000169900	NaN	[NaN]	[257]	1	hSpCas9	negative selection	10389864
31216906	31216929	16	-	28162770	TF1	viability	AGGGCTTTGAGCGCATCCCGCGG	PYDC1	ENSG00000169900	NaN	[NaN]	[132]	1	hSpCas9	negative selection	10389865
31216785	31216808	16	-	28162770	TF1	viability	CGACATGCGCATGTTGGAGGAGG	PYDC1	ENSG00000169900	NaN	[NaN]	[131]	1	hSpCas9	negative selection	10389866
31216768	31216791	16	-	28162770	TF1	viability	AGGAGGCCGCACGGCTGCAGCGG	PYDC1	ENSG00000169900	NaN	[NaN]	[140]	1	hSpCas9	negative selection	10389867
31217010	31217033	16	-	28162770	TF1	viability	AGCCATGGGAACGAAGCGCGAGG	PYDC1	ENSG00000169900	NaN	[NaN]	[0]	1	hSpCas9	negative selection	10389868
31216878	31216901	16	-	28162770	TF1	viability	GCTCGGGCAGCTAGATATCGTGG	PYDC1	ENSG00000169900	NaN	[NaN]	[127]	1	hSpCas9	negative selection	10389869
31216998	31217021	16	-	28162770	SKM1	viability	GAAGCGCGAGGCCATCCTGAAGG	PYDC1	ENSG00000169900	-0.11798652565708623	[123]	[201]	-1	hSpCas9	negative selection	10559226
31216818	31216841	16	-	28162770	SKM1	viability	CTACGCAGCCGAGCTCGTCGTGG	PYDC1	ENSG00000169900	-0.03773038907744275	[17]	[30]	0	hSpCas9	negative selection	10559227
31216987	31217010	16	+	28162770	SKM1	viability	GTTCTCCAGCACCTTCAGGATGG	PYDC1	ENSG00000169900	0.08257873689931183	[124]	[233]	0	hSpCas9	negative selection	10559228
31216974	31216997	16	-	28162770	SKM1	viability	GCTGGAGAACCTGACACCGGAGG	PYDC1	ENSG00000169900	-0.7450397162071214	[72]	[76]	-5	hSpCas9	negative selection	10559229
31216941	31216964	16	-	28162770	SKM1	viability	GTTCAAGATGAAGCTGGGGACGG	PYDC1	ENSG00000169900	-0.007033591854526296	[53]	[94]	0	hSpCas9	negative selection	10559230
31216906	31216929	16	-	28162770	SKM1	viability	AGGGCTTTGAGCGCATCCCGCGG	PYDC1	ENSG00000169900	-0.26351140866204026	[54]	[80]	-2	hSpCas9	negative selection	10559231
31216785	31216808	16	-	28162770	SKM1	viability	CGACATGCGCATGTTGGAGGAGG	PYDC1	ENSG00000169900	0.6286597109875597	[29]	[81]	6	hSpCas9	negative selection	10559232
31216768	31216791	16	-	28162770	SKM1	viability	AGGAGGCCGCACGGCTGCAGCGG	PYDC1	ENSG00000169900	0.7059298576627717	[42]	[123]	6	hSpCas9	negative selection	10559233
31217010	31217033	16	-	28162770	SKM1	viability	AGCCATGGGAACGAAGCGCGAGG	PYDC1	ENSG00000169900	-2.6293566200796095	[6]	[1]	-9	hSpCas9	negative selection	10559234
31216878	31216901	16	-	28162770	SKM1	viability	GCTCGGGCAGCTAGATATCGTGG	PYDC1	ENSG00000169900	-0.20666554825733047	[46]	[71]	-2	hSpCas9	negative selection	10559235
31216998	31217021	16	-	28162770	SKM1	viability	GAAGCGCGAGGCCATCCTGAAGG	PYDC1	ENSG00000169900	-0.11798652565708623	[123]	[201]	-1	hSpCas9	negative selection	10728592
31216818	31216841	16	-	28162770	SKM1	viability	CTACGCAGCCGAGCTCGTCGTGG	PYDC1	ENSG00000169900	-0.03773038907744275	[17]	[30]	0	hSpCas9	negative selection	10728593
31216987	31217010	16	+	28162770	SKM1	viability	GTTCTCCAGCACCTTCAGGATGG	PYDC1	ENSG00000169900	0.08257873689931183	[124]	[233]	0	hSpCas9	negative selection	10728594
31216974	31216997	16	-	28162770	SKM1	viability	GCTGGAGAACCTGACACCGGAGG	PYDC1	ENSG00000169900	-0.7450397162071214	[72]	[76]	-5	hSpCas9	negative selection	10728595
31216941	31216964	16	-	28162770	SKM1	viability	GTTCAAGATGAAGCTGGGGACGG	PYDC1	ENSG00000169900	-0.007033591854526296	[53]	[94]	0	hSpCas9	negative selection	10728596
31216906	31216929	16	-	28162770	SKM1	viability	AGGGCTTTGAGCGCATCCCGCGG	PYDC1	ENSG00000169900	-0.26351140866204026	[54]	[80]	-2	hSpCas9	negative selection	10728597
31216785	31216808	16	-	28162770	SKM1	viability	CGACATGCGCATGTTGGAGGAGG	PYDC1	ENSG00000169900	0.6286597109875597	[29]	[81]	6	hSpCas9	negative selection	10728598
31216768	31216791	16	-	28162770	SKM1	viability	AGGAGGCCGCACGGCTGCAGCGG	PYDC1	ENSG00000169900	0.7059298576627717	[42]	[123]	6	hSpCas9	negative selection	10728599
31217010	31217033	16	-	28162770	SKM1	viability	AGCCATGGGAACGAAGCGCGAGG	PYDC1	ENSG00000169900	-2.6293566200796095	[6]	[1]	-9	hSpCas9	negative selection	10728600
31216878	31216901	16	-	28162770	SKM1	viability	GCTCGGGCAGCTAGATATCGTGG	PYDC1	ENSG00000169900	-0.20666554825733047	[46]	[71]	-2	hSpCas9	negative selection	10728601
31216998	31217021	16	-	28162770	PL21	viability	GAAGCGCGAGGCCATCCTGAAGG	PYDC1	ENSG00000169900	-0.27049021075284096	[387]	[139]	-2	hSpCas9	negative selection	10897958
31216818	31216841	16	-	28162770	PL21	viability	CTACGCAGCCGAGCTCGTCGTGG	PYDC1	ENSG00000169900	1.9745799140741893	[37]	[64]	9	hSpCas9	negative selection	10897959
31216987	31217010	16	+	28162770	PL21	viability	GTTCTCCAGCACCTTCAGGATGG	PYDC1	ENSG00000169900	-0.6663932435030573	[422]	[115]	-5	hSpCas9	negative selection	10897960
31216974	31216997	16	-	28162770	PL21	viability	GCTGGAGAACCTGACACCGGAGG	PYDC1	ENSG00000169900	-1.1093692211439743	[346]	[69]	-6	hSpCas9	negative selection	10897961
31216941	31216964	16	-	28162770	PL21	viability	GTTCAAGATGAAGCTGGGGACGG	PYDC1	ENSG00000169900	0.4058882797058964	[136]	[78]	3	hSpCas9	negative selection	10897962
31216906	31216929	16	-	28162770	PL21	viability	AGGGCTTTGAGCGCATCCCGCGG	PYDC1	ENSG00000169900	0.3430975683313631	[191]	[105]	3	hSpCas9	negative selection	10897963
31216785	31216808	16	-	28162770	PL21	viability	CGACATGCGCATGTTGGAGGAGG	PYDC1	ENSG00000169900	1.7600111342476459	[115]	[170]	9	hSpCas9	negative selection	10897964
31216768	31216791	16	-	28162770	PL21	viability	AGGAGGCCGCACGGCTGCAGCGG	PYDC1	ENSG00000169900	0.957438210752533	[154]	[130]	7	hSpCas9	negative selection	10897965
31217010	31217033	16	-	28162770	PL21	viability	AGCCATGGGAACGAAGCGCGAGG	PYDC1	ENSG00000169900	-1.7067509811191988	[14]	[1]	-8	hSpCas9	negative selection	10897966
31216878	31216901	16	-	28162770	PL21	viability	GCTCGGGCAGCTAGATATCGTGG	PYDC1	ENSG00000169900	0.23729261290678605	[114]	[58]	2	hSpCas9	negative selection	10897967
31216998	31217021	16	-	28162770	P31FUJ	viability	GAAGCGCGAGGCCATCCTGAAGG	PYDC1	ENSG00000169900	0.1144687385874471	[315]	[401]	1	hSpCas9	negative selection	11067324
31216818	31216841	16	-	28162770	P31FUJ	viability	CTACGCAGCCGAGCTCGTCGTGG	PYDC1	ENSG00000169900	-0.2328022044143787	[71]	[71]	-2	hSpCas9	negative selection	11067325
31216987	31217010	16	+	28162770	P31FUJ	viability	GTTCTCCAGCACCTTCAGGATGG	PYDC1	ENSG00000169900	-0.05395412395045007	[393]	[445]	0	hSpCas9	negative selection	11067326
31216974	31216997	16	-	28162770	P31FUJ	viability	GCTGGAGAACCTGACACCGGAGG	PYDC1	ENSG00000169900	-0.9973722599751864	[298]	[175]	-6	hSpCas9	negative selection	11067327
31216941	31216964	16	-	28162770	P31FUJ	viability	GTTCAAGATGAAGCTGGGGACGG	PYDC1	ENSG00000169900	-0.2060021450706636	[159]	[162]	-2	hSpCas9	negative selection	11067328
31216906	31216929	16	-	28162770	P31FUJ	viability	AGGGCTTTGAGCGCATCCCGCGG	PYDC1	ENSG00000169900	-0.26825104041866843	[205]	[200]	-3	hSpCas9	negative selection	11067329
31216785	31216808	16	-	28162770	P31FUJ	viability	CGACATGCGCATGTTGGAGGAGG	PYDC1	ENSG00000169900	0.8352431830087201	[175]	[368]	8	hSpCas9	negative selection	11067330
31216768	31216791	16	-	28162770	P31FUJ	viability	AGGAGGCCGCACGGCTGCAGCGG	PYDC1	ENSG00000169900	0.30635660669365283	[191]	[278]	3	hSpCas9	negative selection	11067331
31217010	31217033	16	-	28162770	P31FUJ	viability	AGCCATGGGAACGAAGCGCGAGG	PYDC1	ENSG00000169900	0.28177096841537974	[13]	[19]	3	hSpCas9	negative selection	11067332
31216878	31216901	16	-	28162770	P31FUJ	viability	GCTCGGGCAGCTAGATATCGTGG	PYDC1	ENSG00000169900	0.39998882139739256	[177]	[275]	4	hSpCas9	negative selection	11067333
31216998	31217021	16	-	28162770	OCIAML5	viability	GAAGCGCGAGGCCATCCTGAAGG	PYDC1	ENSG00000169900	0.4780820308283338	[174]	[439]	4	hSpCas9	negative selection	11236690
31216818	31216841	16	-	28162770	OCIAML5	viability	CTACGCAGCCGAGCTCGTCGTGG	PYDC1	ENSG00000169900	0.8330600917825912	[50]	[163]	7	hSpCas9	negative selection	11236691
31216987	31217010	16	+	28162770	OCIAML5	viability	GTTCTCCAGCACCTTCAGGATGG	PYDC1	ENSG00000169900	-0.5880858251859141	[253]	[304]	-4	hSpCas9	negative selection	11236692
31216974	31216997	16	-	28162770	OCIAML5	viability	GCTGGAGAACCTGACACCGGAGG	PYDC1	ENSG00000169900	-0.507537047039502	[151]	[192]	-3	hSpCas9	negative selection	11236693
31216941	31216964	16	-	28162770	OCIAML5	viability	GTTCAAGATGAAGCTGGGGACGG	PYDC1	ENSG00000169900	-0.06887795993714518	[128]	[221]	0	hSpCas9	negative selection	11236694
31216906	31216929	16	-	28162770	OCIAML5	viability	AGGGCTTTGAGCGCATCCCGCGG	PYDC1	ENSG00000169900	0.6776664091367671	[70]	[204]	6	hSpCas9	negative selection	11236695
31216785	31216808	16	-	28162770	OCIAML5	viability	CGACATGCGCATGTTGGAGGAGG	PYDC1	ENSG00000169900	0.3761035716142689	[177]	[416]	3	hSpCas9	negative selection	11236696
31216768	31216791	16	-	28162770	OCIAML5	viability	AGGAGGCCGCACGGCTGCAGCGG	PYDC1	ENSG00000169900	0.6673075882295825	[104]	[300]	6	hSpCas9	negative selection	11236697
31217010	31217033	16	-	28162770	OCIAML5	viability	AGCCATGGGAACGAAGCGCGAGG	PYDC1	ENSG00000169900	3.3443306419395062	[2]	[54]	9	hSpCas9	negative selection	11236698
31216878	31216901	16	-	28162770	OCIAML5	viability	GCTCGGGCAGCTAGATATCGTGG	PYDC1	ENSG00000169900	1.025559430239327	[82]	[304]	8	hSpCas9	negative selection	11236699
31216998	31217021	16	-	28162770	EOL1	viability	GAAGCGCGAGGCCATCCTGAAGG	PYDC1	ENSG00000169900	-0.3636199174161523	[717]	[293]	-3	hSpCas9	negative selection	11406056
31216818	31216841	16	-	28162770	EOL1	viability	CTACGCAGCCGAGCTCGTCGTGG	PYDC1	ENSG00000169900	1.9796893257629955	[76]	[159]	9	hSpCas9	negative selection	11406057
31216987	31217010	16	+	28162770	EOL1	viability	GTTCTCCAGCACCTTCAGGATGG	PYDC1	ENSG00000169900	0.4143530392513506	[657]	[461]	4	hSpCas9	negative selection	11406058
31216974	31216997	16	-	28162770	EOL1	viability	GCTGGAGAACCTGACACCGGAGG	PYDC1	ENSG00000169900	-1.733835798619991	[523]	[82]	-8	hSpCas9	negative selection	11406059
31216941	31216964	16	-	28162770	EOL1	viability	GTTCAAGATGAAGCTGGGGACGG	PYDC1	ENSG00000169900	0.8548387997591302	[317]	[302]	7	hSpCas9	negative selection	11406060
31216906	31216929	16	-	28162770	EOL1	viability	AGGGCTTTGAGCGCATCCCGCGG	PYDC1	ENSG00000169900	-0.06296128424626848	[344]	[173]	0	hSpCas9	negative selection	11406061
31216785	31216808	16	-	28162770	EOL1	viability	CGACATGCGCATGTTGGAGGAGG	PYDC1	ENSG00000169900	0.5432411296042408	[154]	[118]	5	hSpCas9	negative selection	11406062
31216768	31216791	16	-	28162770	EOL1	viability	AGGAGGCCGCACGGCTGCAGCGG	PYDC1	ENSG00000169900	-0.8409869747924423	[203]	[59]	-5	hSpCas9	negative selection	11406063
31217010	31217033	16	-	28162770	EOL1	viability	AGCCATGGGAACGAAGCGCGAGG	PYDC1	ENSG00000169900	1.0944727730128467	[15]	[17]	8	hSpCas9	negative selection	11406064
31216878	31216901	16	-	28162770	EOL1	viability	GCTCGGGCAGCTAGATATCGTGG	PYDC1	ENSG00000169900	-0.2785440938069773	[197]	[85]	-2	hSpCas9	negative selection	11406065
31216998	31217021	16	-	28162770	MOLM13	viability	GAAGCGCGAGGCCATCCTGAAGG	PYDC1	ENSG00000169900	-0.367299748709751	[627]	[351]	-2	hSpCas9	negative selection	11575422
31216818	31216841	16	-	28162770	MOLM13	viability	CTACGCAGCCGAGCTCGTCGTGG	PYDC1	ENSG00000169900	-0.5948463738033838	[93]	[44]	-3	hSpCas9	negative selection	11575423
31216987	31217010	16	+	28162770	MOLM13	viability	GTTCTCCAGCACCTTCAGGATGG	PYDC1	ENSG00000169900	-0.16762206134001345	[667]	[429]	-1	hSpCas9	negative selection	11575424
31216974	31216997	16	-	28162770	MOLM13	viability	GCTGGAGAACCTGACACCGGAGG	PYDC1	ENSG00000169900	-0.05567257451243407	[367]	[255]	0	hSpCas9	negative selection	11575425
31216941	31216964	16	-	28162770	MOLM13	viability	GTTCAAGATGAAGCTGGGGACGG	PYDC1	ENSG00000169900	0.20066717874735146	[206]	[171]	1	hSpCas9	negative selection	11575426
31216906	31216929	16	-	28162770	MOLM13	viability	AGGGCTTTGAGCGCATCCCGCGG	PYDC1	ENSG00000169900	0.7710809138503554	[247]	[305]	6	hSpCas9	negative selection	11575427
31216785	31216808	16	-	28162770	MOLM13	viability	CGACATGCGCATGTTGGAGGAGG	PYDC1	ENSG00000169900	-0.032264731372215874	[255]	[180]	0	hSpCas9	negative selection	11575428
31216768	31216791	16	-	28162770	MOLM13	viability	AGGAGGCCGCACGGCTGCAGCGG	PYDC1	ENSG00000169900	-1.1736566475429449	[233]	[74]	-6	hSpCas9	negative selection	11575429
31217010	31217033	16	-	28162770	MOLM13	viability	AGCCATGGGAACGAAGCGCGAGG	PYDC1	ENSG00000169900	-4.232550336596514	[25]	[0]	-9	hSpCas9	negative selection	11575430
31216878	31216901	16	-	28162770	MOLM13	viability	GCTCGGGCAGCTAGATATCGTGG	PYDC1	ENSG00000169900	-0.8102663113138782	[210]	[86]	-4	hSpCas9	negative selection	11575431
31216998	31217021	16	-	28162770	HEL	viability	GAAGCGCGAGGCCATCCTGAAGG	PYDC1	ENSG00000169900	1.0171343467818548	[485]	[629]	8	hSpCas9	negative selection	11744788
31216818	31216841	16	-	28162770	HEL	viability	CTACGCAGCCGAGCTCGTCGTGG	PYDC1	ENSG00000169900	1.0683455729893883	[101]	[136]	8	hSpCas9	negative selection	11744789
31216987	31217010	16	+	28162770	HEL	viability	GTTCTCCAGCACCTTCAGGATGG	PYDC1	ENSG00000169900	0.3705229495984468	[598]	[495]	3	hSpCas9	negative selection	11744790
31216974	31216997	16	-	28162770	HEL	viability	GCTGGAGAACCTGACACCGGAGG	PYDC1	ENSG00000169900	-0.6178729115665812	[356]	[148]	-4	hSpCas9	negative selection	11744791
31216941	31216964	16	-	28162770	HEL	viability	GTTCAAGATGAAGCTGGGGACGG	PYDC1	ENSG00000169900	-0.1688160785865328	[257]	[146]	-1	hSpCas9	negative selection	11744792
31216906	31216929	16	-	28162770	HEL	viability	AGGGCTTTGAGCGCATCCCGCGG	PYDC1	ENSG00000169900	0.13638616597556735	[249]	[175]	1	hSpCas9	negative selection	11744793
31216785	31216808	16	-	28162770	HEL	viability	CGACATGCGCATGTTGGAGGAGG	PYDC1	ENSG00000169900	0.4017307324965622	[220]	[186]	3	hSpCas9	negative selection	11744794
31216768	31216791	16	-	28162770	HEL	viability	AGGAGGCCGCACGGCTGCAGCGG	PYDC1	ENSG00000169900	-0.8743196042189958	[165]	[57]	-5	hSpCas9	negative selection	11744795
31217010	31217033	16	-	28162770	HEL	viability	AGCCATGGGAACGAAGCGCGAGG	PYDC1	ENSG00000169900	-0.6791892628870055	[4]	[1]	-4	hSpCas9	negative selection	11744796
31216878	31216901	16	-	28162770	HEL	viability	GCTCGGGCAGCTAGATATCGTGG	PYDC1	ENSG00000169900	0.19022662730285034	[155]	[113]	1	hSpCas9	negative selection	11744797
31216998	31217021	16	-	28162770	MV411	viability	GAAGCGCGAGGCCATCCTGAAGG	PYDC1	ENSG00000169900	0.24038279324882494	[409]	[407]	2	hSpCas9	negative selection	11914154
31216818	31216841	16	-	28162770	MV411	viability	CTACGCAGCCGAGCTCGTCGTGG	PYDC1	ENSG00000169900	0.22471747428269162	[63]	[62]	2	hSpCas9	negative selection	11914155
31216987	31217010	16	+	28162770	MV411	viability	GTTCTCCAGCACCTTCAGGATGG	PYDC1	ENSG00000169900	-0.8324432260859205	[426]	[201]	-5	hSpCas9	negative selection	11914156
31216974	31216997	16	-	28162770	MV411	viability	GCTGGAGAACCTGACACCGGAGG	PYDC1	ENSG00000169900	-1.5010236822212604	[251]	[74]	-7	hSpCas9	negative selection	11914157
31216941	31216964	16	-	28162770	MV411	viability	GTTCAAGATGAAGCTGGGGACGG	PYDC1	ENSG00000169900	0.8324000515039316	[119]	[179]	7	hSpCas9	negative selection	11914158
31216906	31216929	16	-	28162770	MV411	viability	AGGGCTTTGAGCGCATCCCGCGG	PYDC1	ENSG00000169900	0.10088888742983347	[175]	[158]	0	hSpCas9	negative selection	11914159
31216785	31216808	16	-	28162770	MV411	viability	CGACATGCGCATGTTGGAGGAGG	PYDC1	ENSG00000169900	0.33385230260024845	[161]	[171]	3	hSpCas9	negative selection	11914160
31216768	31216791	16	-	28162770	MV411	viability	AGGAGGCCGCACGGCTGCAGCGG	PYDC1	ENSG00000169900	1.1869729095188808	[133]	[256]	9	hSpCas9	negative selection	11914161
31217010	31217033	16	-	28162770	MV411	viability	AGCCATGGGAACGAAGCGCGAGG	PYDC1	ENSG00000169900	2.334900392033115	[3]	[16]	9	hSpCas9	negative selection	11914162
31216878	31216901	16	-	28162770	MV411	viability	GCTCGGGCAGCTAGATATCGTGG	PYDC1	ENSG00000169900	0.30585423700809716	[120]	[125]	2	hSpCas9	negative selection	11914163
31216998	31217021	16	-	28162770	MONOMAC1	viability	GAAGCGCGAGGCCATCCTGAAGG	PYDC1	ENSG00000169900	-0.28653499789865633	[265]	[249]	-3	hSpCas9	negative selection	12083520
31216818	31216841	16	-	28162770	MONOMAC1	viability	CTACGCAGCCGAGCTCGTCGTGG	PYDC1	ENSG00000169900	-1.4485756140555182	[49]	[20]	-8	hSpCas9	negative selection	12083521
31216987	31217010	16	+	28162770	MONOMAC1	viability	GTTCTCCAGCACCTTCAGGATGG	PYDC1	ENSG00000169900	-0.16789050140003736	[244]	[249]	-1	hSpCas9	negative selection	12083522
31216974	31216997	16	-	28162770	MONOMAC1	viability	GCTGGAGAACCTGACACCGGAGG	PYDC1	ENSG00000169900	-0.24120443033512207	[198]	[192]	-2	hSpCas9	negative selection	12083523
31216941	31216964	16	-	28162770	MONOMAC1	viability	GTTCAAGATGAAGCTGGGGACGG	PYDC1	ENSG00000169900	-0.10392744266807219	[89]	[95]	-1	hSpCas9	negative selection	12083524
31216906	31216929	16	-	28162770	MONOMAC1	viability	AGGGCTTTGAGCGCATCCCGCGG	PYDC1	ENSG00000169900	0.18998627604969356	[142]	[186]	2	hSpCas9	negative selection	12083525
31216785	31216808	16	-	28162770	MONOMAC1	viability	CGACATGCGCATGTTGGAGGAGG	PYDC1	ENSG00000169900	1.4692257557634507	[91]	[291]	9	hSpCas9	negative selection	12083526
31216768	31216791	16	-	28162770	MONOMAC1	viability	AGGAGGCCGCACGGCTGCAGCGG	PYDC1	ENSG00000169900	0.12258108714060756	[124]	[155]	1	hSpCas9	negative selection	12083527
31217010	31217033	16	-	28162770	MONOMAC1	viability	AGCCATGGGAACGAAGCGCGAGG	PYDC1	ENSG00000169900	-3.197036847059554	[7]	[0]	-9	hSpCas9	negative selection	12083528
31216878	31216901	16	-	28162770	MONOMAC1	viability	GCTCGGGCAGCTAGATATCGTGG	PYDC1	ENSG00000169900	0.45947891468663626	[58]	[92]	4	hSpCas9	negative selection	12083529
31216998	31217021	16	-	28162770	OCIAML2	viability	GAAGCGCGAGGCCATCCTGAAGG	PYDC1	ENSG00000169900	-0.838936274176014	[80]	[250]	-5	hSpCas9	negative selection	12252886
31216818	31216841	16	-	28162770	OCIAML2	viability	CTACGCAGCCGAGCTCGTCGTGG	PYDC1	ENSG00000169900	-0.2689959640725106	[14]	[68]	-2	hSpCas9	negative selection	12252887
31216987	31217010	16	+	28162770	OCIAML2	viability	GTTCTCCAGCACCTTCAGGATGG	PYDC1	ENSG00000169900	0.16744401193855762	[79]	[497]	1	hSpCas9	negative selection	12252888
31216974	31216997	16	-	28162770	OCIAML2	viability	GCTGGAGAACCTGACACCGGAGG	PYDC1	ENSG00000169900	-0.6366397766810905	[68]	[245]	-5	hSpCas9	negative selection	12252889
31216941	31216964	16	-	28162770	OCIAML2	viability	GTTCAAGATGAAGCTGGGGACGG	PYDC1	ENSG00000169900	-0.027281929939940386	[40]	[222]	0	hSpCas9	negative selection	12252890
31216906	31216929	16	-	28162770	OCIAML2	viability	AGGGCTTTGAGCGCATCCCGCGG	PYDC1	ENSG00000169900	0.942672622665935	[25]	[276]	8	hSpCas9	negative selection	12252891
31216785	31216808	16	-	28162770	OCIAML2	viability	CGACATGCGCATGTTGGAGGAGG	PYDC1	ENSG00000169900	0.7937107780922574	[22]	[220]	7	hSpCas9	negative selection	12252892
31216768	31216791	16	-	28162770	OCIAML2	viability	AGGAGGCCGCACGGCTGCAGCGG	PYDC1	ENSG00000169900	-0.00030989046212781535	[23]	[132]	0	hSpCas9	negative selection	12252893
31217010	31217033	16	-	28162770	OCIAML2	viability	AGCCATGGGAACGAAGCGCGAGG	PYDC1	ENSG00000169900	-0.2689959640725106	[4]	[22]	-2	hSpCas9	negative selection	12252894
31216878	31216901	16	-	28162770	OCIAML2	viability	GCTCGGGCAGCTAGATATCGTGG	PYDC1	ENSG00000169900	0.16408571067609445	[18]	[117]	1	hSpCas9	negative selection	12252895
31216998	31217021	16	-	28162770	OCIAML3	viability	GAAGCGCGAGGCCATCCTGAAGG	PYDC1	ENSG00000169900	0.7362197777816859	[103]	[522]	6	hSpCas9	negative selection	12422252
31216818	31216841	16	-	28162770	OCIAML3	viability	CTACGCAGCCGAGCTCGTCGTGG	PYDC1	ENSG00000169900	-0.7272741711876274	[16]	[30]	-5	hSpCas9	negative selection	12422253
31216987	31217010	16	+	28162770	OCIAML3	viability	GTTCTCCAGCACCTTCAGGATGG	PYDC1	ENSG00000169900	-0.7921347832829748	[112]	[196]	-5	hSpCas9	negative selection	12422254
31216974	31216997	16	-	28162770	OCIAML3	viability	GCTGGAGAACCTGACACCGGAGG	PYDC1	ENSG00000169900	-0.819567340739294	[75]	[129]	-6	hSpCas9	negative selection	12422255
31216941	31216964	16	-	28162770	OCIAML3	viability	GTTCAAGATGAAGCTGGGGACGG	PYDC1	ENSG00000169900	-0.009045139603007013	[33]	[101]	0	hSpCas9	negative selection	12422256
31216906	31216929	16	-	28162770	OCIAML3	viability	AGGGCTTTGAGCGCATCCCGCGG	PYDC1	ENSG00000169900	0.05926087378790193	[54]	[172]	0	hSpCas9	negative selection	12422257
31216785	31216808	16	-	28162770	OCIAML3	viability	CGACATGCGCATGTTGGAGGAGG	PYDC1	ENSG00000169900	-0.259588601253604	[45]	[115]	-2	hSpCas9	negative selection	12422258
31216768	31216791	16	-	28162770	OCIAML3	viability	AGGAGGCCGCACGGCTGCAGCGG	PYDC1	ENSG00000169900	-0.5615861626317857	[43]	[89]	-4	hSpCas9	negative selection	12422259
31217010	31217033	16	-	28162770	OCIAML3	viability	AGCCATGGGAACGAAGCGCGAGG	PYDC1	ENSG00000169900	1.2133472817334408	[3]	[27]	8	hSpCas9	negative selection	12422260
31216878	31216901	16	-	28162770	OCIAML3	viability	GCTCGGGCAGCTAGATATCGTGG	PYDC1	ENSG00000169900	1.0148016023513609	[29]	[182]	8	hSpCas9	negative selection	12422261