Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:5163
• Symbol:Pdk1
• Description:pyruvate dehydrogenase kinase 1

DataSource: http://genomecrispr.dkfz.de/#!/results/Pdk1

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
172556212	172556235	2	-	26472758	Jiyoye	viability	GAAGCTGCGGCTGAAGCCGGCGG	PDK1	ENSG00000152256	-0.20287810017811325	[57]	[37]	-1	hSpCas9	negative selection	118308
172556165	172556188	2	+	26472758	Jiyoye	viability	GCTGCTTCGCGGAGCCGCCTTGG	PDK1	ENSG00000152256	1.6872833006986085	[27]	[67]	8	hSpCas9	negative selection	118309
172586275	172586298	2	+	26472758	Jiyoye	viability	TAGATGAGTGACCGAGGAGGTGG	PDK1	ENSG00000152256	-0.09639879237462774	[111]	[78]	0	hSpCas9	negative selection	118310
172586356	172586379	2	-	26472758	Jiyoye	viability	GCGCGGGAGGTCTCAACACGAGG	PDK1	ENSG00000152256	0.9921378822270296	[57]	[86]	6	hSpCas9	negative selection	118311
172556143	172556166	2	+	26472758	Jiyoye	viability	GACTCGGCATGAGGCTGGCGCGG	PDK1	ENSG00000152256	-0.554856768295106	[149]	[76]	-4	hSpCas9	negative selection	118312
172564578	172564601	2	+	26472758	Jiyoye	viability	ATACAAGGAGAGCTTTGGGGTGG	PDK1	ENSG00000152256	-0.015204093114138395	[196]	[146]	0	hSpCas9	negative selection	118313
172570744	172570767	2	+	26472758	Jiyoye	viability	ATGGAACACCATGCCAACAGAGG	PDK1	ENSG00000152256	1.0327798667243757	[34]	[53]	6	hSpCas9	negative selection	118314
172556314	172556337	2	-	26472758	Jiyoye	viability	GAACTGCTTCATGGAGAGCGGGG	PDK1	ENSG00000152256	-0.20050719571536657	[31]	[20]	-1	hSpCas9	negative selection	118315
172570779	172570802	2	+	26472758	Jiyoye	viability	TATTCAAGTTCATGTCACGCTGG	PDK1	ENSG00000152256	0.8222128807847171	[26]	[35]	6	hSpCas9	negative selection	118316
172586372	172586395	2	-	26472758	Jiyoye	viability	ACATACCAGAGGCACTGCGCGGG	PDK1	ENSG00000152256	1.0238467419543675	[44]	[68]	6	hSpCas9	negative selection	118317
172556212	172556235	2	-	26472758	KBM7	viability	GAAGCTGCGGCTGAAGCCGGCGG	PDK1	ENSG00000152256	-1.0776442916290718	[161,69]	[16,31]	-7	hSpCas9	negative selection	309426
172556165	172556188	2	+	26472758	KBM7	viability	GCTGCTTCGCGGAGCCGCCTTGG	PDK1	ENSG00000152256	0.22431066145667833	[346,233]	[153,159]	2	hSpCas9	negative selection	309427
172586275	172586298	2	+	26472758	KBM7	viability	TAGATGAGTGACCGAGGAGGTGG	PDK1	ENSG00000152256	0.9447880812757117	[389,304]	[328,296]	8	hSpCas9	negative selection	309428
172586356	172586379	2	-	26472758	KBM7	viability	GCGCGGGAGGTCTCAACACGAGG	PDK1	ENSG00000152256	1.4300930230605728	[181,192]	[287,195]	9	hSpCas9	negative selection	309429
172556143	172556166	2	+	26472758	KBM7	viability	GACTCGGCATGAGGCTGGCGCGG	PDK1	ENSG00000152256	0.04206016168894283	[572,548]	[275,268]	0	hSpCas9	negative selection	309430
172564578	172564601	2	+	26472758	KBM7	viability	ATACAAGGAGAGCTTTGGGGTGG	PDK1	ENSG00000152256	-0.17152311296440592	[667,278]	[268,119]	-2	hSpCas9	negative selection	309431
172570744	172570767	2	+	26472758	KBM7	viability	ATGGAACACCATGCCAACAGAGG	PDK1	ENSG00000152256	0.7790377622865754	[254,206]	[188,181]	8	hSpCas9	negative selection	309432
172556314	172556337	2	-	26472758	KBM7	viability	GAACTGCTTCATGGAGAGCGGGG	PDK1	ENSG00000152256	0.7863613711457882	[192,221]	[211,132]	8	hSpCas9	negative selection	309433
172570779	172570802	2	+	26472758	KBM7	viability	TATTCAAGTTCATGTCACGCTGG	PDK1	ENSG00000152256	1.331864360539	[145,265]	[199,298]	9	hSpCas9	negative selection	309434
172586372	172586395	2	-	26472758	KBM7	viability	ACATACCAGAGGCACTGCGCGGG	PDK1	ENSG00000152256	-0.3066241158136185	[265,299]	[131,87]	-3	hSpCas9	negative selection	309435
172556212	172556235	2	-	26472758	Raji	viability	GAAGCTGCGGCTGAAGCCGGCGG	PDK1	ENSG00000152256	-0.5791169918096191	[102]	[15]	-4	hSpCas9	negative selection	500544
172556165	172556188	2	+	26472758	Raji	viability	GCTGCTTCGCGGAGCCGCCTTGG	PDK1	ENSG00000152256	0.18138411681737648	[170]	[44]	1	hSpCas9	negative selection	500545
172586275	172586298	2	+	26472758	Raji	viability	TAGATGAGTGACCGAGGAGGTGG	PDK1	ENSG00000152256	0.0037609042994420083	[201]	[46]	0	hSpCas9	negative selection	500546
172586356	172586379	2	-	26472758	Raji	viability	GCGCGGGAGGTCTCAACACGAGG	PDK1	ENSG00000152256	0.7448134559888913	[89]	[34]	7	hSpCas9	negative selection	500547
172556143	172556166	2	+	26472758	Raji	viability	GACTCGGCATGAGGCTGGCGCGG	PDK1	ENSG00000152256	0.5903250991542467	[165]	[57]	5	hSpCas9	negative selection	500548
172564578	172564601	2	+	26472758	Raji	viability	ATACAAGGAGAGCTTTGGGGTGG	PDK1	ENSG00000152256	-0.3769466022410656	[262]	[46]	-3	hSpCas9	negative selection	500549
172570744	172570767	2	+	26472758	Raji	viability	ATGGAACACCATGCCAACAGAGG	PDK1	ENSG00000152256	0.2532344018370545	[140]	[38]	2	hSpCas9	negative selection	500550
172556314	172556337	2	-	26472758	Raji	viability	GAACTGCTTCATGGAGAGCGGGG	PDK1	ENSG00000152256	-0.9857258690178821	[127]	[14]	-6	hSpCas9	negative selection	500551
172570779	172570802	2	+	26472758	Raji	viability	TATTCAAGTTCATGTCACGCTGG	PDK1	ENSG00000152256	-0.42313118132518057	[103]	[17]	-3	hSpCas9	negative selection	500552
172586372	172586395	2	-	26472758	Raji	viability	ACATACCAGAGGCACTGCGCGGG	PDK1	ENSG00000152256	-0.9125160220641055	[145]	[17]	-6	hSpCas9	negative selection	500553
172556212	172556235	2	-	26472758	K562	viability	GAAGCTGCGGCTGAAGCCGGCGG	PDK1	ENSG00000152256	0.18301818300230344	[95]	[91]	1	hSpCas9	negative selection	691662
172556165	172556188	2	+	26472758	K562	viability	GCTGCTTCGCGGAGCCGCCTTGG	PDK1	ENSG00000152256	0.2933283281473934	[173]	[179]	2	hSpCas9	negative selection	691663
172586275	172586298	2	+	26472758	K562	viability	TAGATGAGTGACCGAGGAGGTGG	PDK1	ENSG00000152256	-0.5239110374090945	[464]	[272]	-3	hSpCas9	negative selection	691664
172586356	172586379	2	-	26472758	K562	viability	GCGCGGGAGGTCTCAACACGAGG	PDK1	ENSG00000152256	0.33698484640251947	[165]	[176]	2	hSpCas9	negative selection	691665
172556143	172556166	2	+	26472758	K562	viability	GACTCGGCATGAGGCTGGCGCGG	PDK1	ENSG00000152256	0.930691113880945	[306]	[493]	7	hSpCas9	negative selection	691666
172564578	172564601	2	+	26472758	K562	viability	ATACAAGGAGAGCTTTGGGGTGG	PDK1	ENSG00000152256	-1.3608026120385095	[501]	[164]	-6	hSpCas9	negative selection	691667
172570744	172570767	2	+	26472758	K562	viability	ATGGAACACCATGCCAACAGAGG	PDK1	ENSG00000152256	-0.06536393735882606	[206]	[166]	0	hSpCas9	negative selection	691668
172556314	172556337	2	-	26472758	K562	viability	GAACTGCTTCATGGAGAGCGGGG	PDK1	ENSG00000152256	-1.5874585135252262	[177]	[49]	-7	hSpCas9	negative selection	691669
172570779	172570802	2	+	26472758	K562	viability	TATTCAAGTTCATGTCACGCTGG	PDK1	ENSG00000152256	0.0437213774293177	[153]	[133]	0	hSpCas9	negative selection	691670
172586372	172586395	2	-	26472758	K562	viability	ACATACCAGAGGCACTGCGCGGG	PDK1	ENSG00000152256	-0.7685203280410513	[223]	[110]	-4	hSpCas9	negative selection	691671
172556282	172556305	2	-	26627737	DLD1	viability	AGCGCGCGTAGAAGTCCACCTGG	PDK1	ENSG00000152256	-0.08785348168645024	[179]	[44,94,24]	-1	hSpCas9	negative selection	809287
172558828	172558851	2	+	26627737	DLD1	viability	CCGTTCAATTGGTACAAAGCTGG	PDK1	ENSG00000152256	0.7141049205299843	[806]	[447,465,340]	7	hSpCas9	negative selection	809288
172564563	172564586	2	-	26627737	DLD1	viability	CCTTGTATTCAATCACACCCTGG	PDK1	ENSG00000152256	0.8011261859845277	[320]	[93,280,156]	7	hSpCas9	negative selection	809289
172568748	172568771	2	+	26627737	DLD1	viability	ACCAGGACAGCCAATACAAGTGG	PDK1	ENSG00000152256	-0.4857884508873963	[931]	[271,273,97]	-5	hSpCas9	negative selection	809290
172586372	172586395	2	-	26627737	DLD1	viability	ACATACCAGAGGCACTGCGCGGG	PDK1	ENSG00000152256	-0.13827381422290042	[989]	[210,314,313]	-1	hSpCas9	negative selection	809291
172595859	172595882	2	-	26627737	DLD1	viability	CAGGCAGCTTTGTTATACACTGG	PDK1	ENSG00000152256	0.38575430696076773	[631]	[169,242,346]	4	hSpCas9	negative selection	809292
172556282	172556305	2	-	26627737	GBM cells	viability after 5 days	AGCGCGCGTAGAAGTCCACCTGG	PDK1	ENSG00000152256	-0.6947658429365796	[165]	[54,54]	-8	hSpCas9	negative selection	891602
172558828	172558851	2	+	26627737	GBM cells	viability after 5 days	CCGTTCAATTGGTACAAAGCTGG	PDK1	ENSG00000152256	0.16316625887615088	[591]	[407,302]	2	hSpCas9	negative selection	891603
172564563	172564586	2	-	26627737	GBM cells	viability after 5 days	CCTTGTATTCAATCACACCCTGG	PDK1	ENSG00000152256	0.03356340158046761	[275]	[154,147]	0	hSpCas9	negative selection	891604
172568748	172568771	2	+	26627737	GBM cells	viability after 5 days	ACCAGGACAGCCAATACAAGTGG	PDK1	ENSG00000152256	-0.23688534265200056	[422]	[175,208]	-4	hSpCas9	negative selection	891605
172586372	172586395	2	-	26627737	GBM cells	viability after 5 days	ACATACCAGAGGCACTGCGCGGG	PDK1	ENSG00000152256	-0.6262555409932129	[448]	[154,156]	-7	hSpCas9	negative selection	891606
172595859	172595882	2	-	26627737	GBM cells	viability after 5 days	CAGGCAGCTTTGTTATACACTGG	PDK1	ENSG00000152256	-0.5002405827865032	[541]	[148,261]	-7	hSpCas9	negative selection	891607
172556282	172556305	2	-	26627737	GBM cells	viability after 13 days	AGCGCGCGTAGAAGTCCACCTGG	PDK1	ENSG00000152256	-0.11840819843324513	[165]	[93,73]	-1	hSpCas9	negative selection	973917
172558828	172558851	2	+	26627737	GBM cells	viability after 13 days	CCGTTCAATTGGTACAAAGCTGG	PDK1	ENSG00000152256	-0.15374658330144864	[591]	[387,207]	-2	hSpCas9	negative selection	973918
172564563	172564586	2	-	26627737	GBM cells	viability after 13 days	CCTTGTATTCAATCACACCCTGG	PDK1	ENSG00000152256	0.12256711783691365	[275]	[151,171]	1	hSpCas9	negative selection	973919
172568748	172568771	2	+	26627737	GBM cells	viability after 13 days	ACCAGGACAGCCAATACAAGTGG	PDK1	ENSG00000152256	-0.9055130249035231	[422]	[132,113]	-8	hSpCas9	negative selection	973920
172586372	172586395	2	-	26627737	GBM cells	viability after 13 days	ACATACCAGAGGCACTGCGCGGG	PDK1	ENSG00000152256	-0.015007069822470576	[448]	[223,254]	0	hSpCas9	negative selection	973921
172595859	172595882	2	-	26627737	GBM cells	viability after 13 days	CAGGCAGCTTTGTTATACACTGG	PDK1	ENSG00000152256	-0.3422935625698649	[541]	[301,174]	-4	hSpCas9	negative selection	973922
172556282	172556305	2	-	26627737	GBM cells	viability after 21 days	AGCGCGCGTAGAAGTCCACCTGG	PDK1	ENSG00000152256	0.11219532515781644	[165]	[97,96]	1	hSpCas9	negative selection	1056232
172558828	172558851	2	+	26627737	GBM cells	viability after 21 days	CCGTTCAATTGGTACAAAGCTGG	PDK1	ENSG00000152256	-0.7546475617074097	[591]	[222,160]	-6	hSpCas9	negative selection	1056233
172564563	172564586	2	-	26627737	GBM cells	viability after 21 days	CCTTGTATTCAATCACACCCTGG	PDK1	ENSG00000152256	-0.07111267238551941	[275]	[148,136]	0	hSpCas9	negative selection	1056234
172568748	172568771	2	+	26627737	GBM cells	viability after 21 days	ACCAGGACAGCCAATACAAGTGG	PDK1	ENSG00000152256	-0.7113381939737289	[422]	[131,147]	-6	hSpCas9	negative selection	1056235
172586372	172586395	2	-	26627737	GBM cells	viability after 21 days	ACATACCAGAGGCACTGCGCGGG	PDK1	ENSG00000152256	-0.050142606182390304	[448]	[244,226]	0	hSpCas9	negative selection	1056236
172595859	172595882	2	-	26627737	GBM cells	viability after 21 days	CAGGCAGCTTTGTTATACACTGG	PDK1	ENSG00000152256	-0.7306018107740604	[541]	[201,154]	-6	hSpCas9	negative selection	1056237
172556282	172556305	2	-	26627737	RPE1	viability after 9 days	AGCGCGCGTAGAAGTCCACCTGG	PDK1	ENSG00000152256	-0.9789158018899347	[1087]	[174,169]	-6	hSpCas9	negative selection	1138547
172558828	172558851	2	+	26627737	RPE1	viability after 9 days	CCGTTCAATTGGTACAAAGCTGG	PDK1	ENSG00000152256	0.1433881561381587	[1717]	[404,837]	1	hSpCas9	negative selection	1138548
172564563	172564586	2	-	26627737	RPE1	viability after 9 days	CCTTGTATTCAATCACACCCTGG	PDK1	ENSG00000152256	-0.46774425571700706	[1330]	[206,422]	-3	hSpCas9	negative selection	1138549
172568748	172568771	2	+	26627737	RPE1	viability after 9 days	ACCAGGACAGCCAATACAAGTGG	PDK1	ENSG00000152256	-0.4107619077334832	[1351]	[420,185]	-3	hSpCas9	negative selection	1138550
172586372	172586395	2	-	26627737	RPE1	viability after 9 days	ACATACCAGAGGCACTGCGCGGG	PDK1	ENSG00000152256	-0.3986006727818775	[1513]	[235,518]	-3	hSpCas9	negative selection	1138551
172595859	172595882	2	-	26627737	RPE1	viability after 9 days	CAGGCAGCTTTGTTATACACTGG	PDK1	ENSG00000152256	-0.5618733728248162	[1178]	[177,342]	-4	hSpCas9	negative selection	1138552
172556282	172556305	2	-	26627737	RPE1	viability after 12 days	AGCGCGCGTAGAAGTCCACCTGG	PDK1	ENSG00000152256	-0.9724595789866116	[1087]	[164,131]	-6	hSpCas9	negative selection	1220862
172558828	172558851	2	+	26627737	RPE1	viability after 12 days	CCGTTCAATTGGTACAAAGCTGG	PDK1	ENSG00000152256	-0.22939765881863838	[1717]	[349,439]	-1	hSpCas9	negative selection	1220863
172564563	172564586	2	-	26627737	RPE1	viability after 12 days	CCTTGTATTCAATCACACCCTGG	PDK1	ENSG00000152256	0.21518132713906002	[1330]	[469,356]	1	hSpCas9	negative selection	1220864
172568748	172568771	2	+	26627737	RPE1	viability after 12 days	ACCAGGACAGCCAATACAAGTGG	PDK1	ENSG00000152256	-0.4479368020123704	[1351]	[258,273]	-3	hSpCas9	negative selection	1220865
172586372	172586395	2	-	26627737	RPE1	viability after 12 days	ACATACCAGAGGCACTGCGCGGG	PDK1	ENSG00000152256	-0.42051739714342184	[1513]	[368,234]	-3	hSpCas9	negative selection	1220866
172595859	172595882	2	-	26627737	RPE1	viability after 12 days	CAGGCAGCTTTGTTATACACTGG	PDK1	ENSG00000152256	-0.11755320323164126	[1178]	[273,310]	-1	hSpCas9	negative selection	1220867
172556282	172556305	2	-	26627737	RPE1	viability after 15 days	AGCGCGCGTAGAAGTCCACCTGG	PDK1	ENSG00000152256	-1.0365254024949748	[1087]	[175,124]	-6	hSpCas9	negative selection	1303177
172558828	172558851	2	+	26627737	RPE1	viability after 15 days	CCGTTCAATTGGTACAAAGCTGG	PDK1	ENSG00000152256	0.26977416107055663	[1717]	[393,770]	1	hSpCas9	negative selection	1303178
172564563	172564586	2	-	26627737	RPE1	viability after 15 days	CCTTGTATTCAATCACACCCTGG	PDK1	ENSG00000152256	-0.156342683803961	[1330]	[402,274]	-1	hSpCas9	negative selection	1303179
172568748	172568771	2	+	26627737	RPE1	viability after 15 days	ACCAGGACAGCCAATACAAGTGG	PDK1	ENSG00000152256	-0.6212406436455254	[1351]	[240,255]	-4	hSpCas9	negative selection	1303180
172586372	172586395	2	-	26627737	RPE1	viability after 15 days	ACATACCAGAGGCACTGCGCGGG	PDK1	ENSG00000152256	-0.17638963948155806	[1513]	[463,296]	-1	hSpCas9	negative selection	1303181
172595859	172595882	2	-	26627737	RPE1	viability after 15 days	CAGGCAGCTTTGTTATACACTGG	PDK1	ENSG00000152256	-0.1507581667397489	[1178]	[332,268]	-1	hSpCas9	negative selection	1303182
172556282	172556305	2	-	26627737	RPE1	viability after 18 days	AGCGCGCGTAGAAGTCCACCTGG	PDK1	ENSG00000152256	-0.5629233285600471	[1087]	[147,252]	-4	hSpCas9	negative selection	1385492
172558828	172558851	2	+	26627737	RPE1	viability after 18 days	CCGTTCAATTGGTACAAAGCTGG	PDK1	ENSG00000152256	-0.14004691303335537	[1717]	[354,490]	-1	hSpCas9	negative selection	1385493
172564563	172564586	2	-	26627737	RPE1	viability after 18 days	CCTTGTATTCAATCACACCCTGG	PDK1	ENSG00000152256	-0.17250059017348718	[1330]	[324,311]	-1	hSpCas9	negative selection	1385494
172568748	172568771	2	+	26627737	RPE1	viability after 18 days	ACCAGGACAGCCAATACAAGTGG	PDK1	ENSG00000152256	-0.22438519815805835	[1351]	[262,364]	-1	hSpCas9	negative selection	1385495
172586372	172586395	2	-	26627737	RPE1	viability after 18 days	ACATACCAGAGGCACTGCGCGGG	PDK1	ENSG00000152256	-0.03127474102018857	[1513]	[379,420]	0	hSpCas9	negative selection	1385496
172595859	172595882	2	-	26627737	RPE1	viability after 18 days	CAGGCAGCTTTGTTATACACTGG	PDK1	ENSG00000152256	-0.2675772810582051	[1178]	[185,347]	-2	hSpCas9	negative selection	1385497
172556282	172556305	2	-	26627737	HeLa	viability after 8 days	AGCGCGCGTAGAAGTCCACCTGG	PDK1	ENSG00000152256	1.3592673754107305	[100]	[120,45,168]	8	hSpCas9	negative selection	1467807
172558828	172558851	2	+	26627737	HeLa	viability after 8 days	CCGTTCAATTGGTACAAAGCTGG	PDK1	ENSG00000152256	0.08302067033524185	[885]	[498,425,325]	0	hSpCas9	negative selection	1467808
172564563	172564586	2	-	26627737	HeLa	viability after 8 days	CCTTGTATTCAATCACACCCTGG	PDK1	ENSG00000152256	-0.07450684698871146	[602]	[243,276,226]	0	hSpCas9	negative selection	1467809
172568748	172568771	2	+	26627737	HeLa	viability after 8 days	ACCAGGACAGCCAATACAAGTGG	PDK1	ENSG00000152256	0.48521177363700924	[541]	[430,301,282]	4	hSpCas9	negative selection	1467810
172586372	172586395	2	-	26627737	HeLa	viability after 8 days	ACATACCAGAGGCACTGCGCGGG	PDK1	ENSG00000152256	-0.937528269370409	[532]	[164,57,147]	-7	hSpCas9	negative selection	1467811
172595859	172595882	2	-	26627737	HeLa	viability after 8 days	CAGGCAGCTTTGTTATACACTGG	PDK1	ENSG00000152256	0.2777310320387666	[581]	[362,272,297]	2	hSpCas9	negative selection	1467812
172556282	172556305	2	-	26627737	HeLa	viability after 12 days	AGCGCGCGTAGAAGTCCACCTGG	PDK1	ENSG00000152256	0.25365269303295856	[100]	[26,83,33]	2	hSpCas9	negative selection	1550122
172558828	172558851	2	+	26627737	HeLa	viability after 12 days	CCGTTCAATTGGTACAAAGCTGG	PDK1	ENSG00000152256	0.2789424160439691	[885]	[510,365,465]	2	hSpCas9	negative selection	1550123
172564563	172564586	2	-	26627737	HeLa	viability after 12 days	CCTTGTATTCAATCACACCCTGG	PDK1	ENSG00000152256	0.07358884016292289	[602]	[470,146,186]	0	hSpCas9	negative selection	1550124
172568748	172568771	2	+	26627737	HeLa	viability after 12 days	ACCAGGACAGCCAATACAAGTGG	PDK1	ENSG00000152256	-0.10665192888415725	[541]	[183,239,195]	-1	hSpCas9	negative selection	1550125
172586372	172586395	2	-	26627737	HeLa	viability after 12 days	ACATACCAGAGGCACTGCGCGGG	PDK1	ENSG00000152256	-0.18626193959297555	[532]	[231,201,146]	-2	hSpCas9	negative selection	1550126
172595859	172595882	2	-	26627737	HeLa	viability after 12 days	CAGGCAGCTTTGTTATACACTGG	PDK1	ENSG00000152256	0.7375053638911915	[581]	[389,322,497]	6	hSpCas9	negative selection	1550127
172556282	172556305	2	-	26627737	HeLa	viability after 15 days	AGCGCGCGTAGAAGTCCACCTGG	PDK1	ENSG00000152256	1.2261286464119676	[100]	[67,135,83]	8	hSpCas9	negative selection	1632437
172558828	172558851	2	+	26627737	HeLa	viability after 15 days	CCGTTCAATTGGTACAAAGCTGG	PDK1	ENSG00000152256	0.02863676036540319	[885]	[152,555,399]	0	hSpCas9	negative selection	1632438
172564563	172564586	2	-	26627737	HeLa	viability after 15 days	CCTTGTATTCAATCACACCCTGG	PDK1	ENSG00000152256	0.13825475881044125	[602]	[207,336,265]	1	hSpCas9	negative selection	1632439
172568748	172568771	2	+	26627737	HeLa	viability after 15 days	ACCAGGACAGCCAATACAAGTGG	PDK1	ENSG00000152256	0.3613053394775257	[541]	[286,391,161]	3	hSpCas9	negative selection	1632440
172586372	172586395	2	-	26627737	HeLa	viability after 15 days	ACATACCAGAGGCACTGCGCGGG	PDK1	ENSG00000152256	-0.1653110120457113	[532]	[258,158,158]	-1	hSpCas9	negative selection	1632441
172595859	172595882	2	-	26627737	HeLa	viability after 15 days	CAGGCAGCTTTGTTATACACTGG	PDK1	ENSG00000152256	0.4176400733827911	[581]	[299,316,333]	3	hSpCas9	negative selection	1632442
172556282	172556305	2	-	26627737	HeLa	viability after 18 days	AGCGCGCGTAGAAGTCCACCTGG	PDK1	ENSG00000152256	1.2097278301287255	[100]	[43,111,83]	8	hSpCas9	negative selection	1714752
172558828	172558851	2	+	26627737	HeLa	viability after 18 days	CCGTTCAATTGGTACAAAGCTGG	PDK1	ENSG00000152256	0.030724097276062512	[885]	[107,454,399]	0	hSpCas9	negative selection	1714753
172564563	172564586	2	-	26627737	HeLa	viability after 18 days	CCTTGTATTCAATCACACCCTGG	PDK1	ENSG00000152256	0.17351673812840307	[602]	[146,285,265]	1	hSpCas9	negative selection	1714754
172568748	172568771	2	+	26627737	HeLa	viability after 18 days	ACCAGGACAGCCAATACAAGTGG	PDK1	ENSG00000152256	0.3819942525850149	[541]	[196,328,161]	3	hSpCas9	negative selection	1714755
172586372	172586395	2	-	26627737	HeLa	viability after 18 days	ACATACCAGAGGCACTGCGCGGG	PDK1	ENSG00000152256	-0.10858201261613315	[532]	[190,128,158]	-1	hSpCas9	negative selection	1714756
172595859	172595882	2	-	26627737	HeLa	viability after 18 days	CAGGCAGCTTTGTTATACACTGG	PDK1	ENSG00000152256	0.4146429031884519	[581]	[197,264,333]	3	hSpCas9	negative selection	1714757
172556282	172556305	2	-	26627737	HCT116	viability after 6 days	AGCGCGCGTAGAAGTCCACCTGG	PDK1	ENSG00000152256	0.9923309753835097	[194]	[11,87]	5	hSpCas9	negative selection	1797067
172558828	172558851	2	+	26627737	HCT116	viability after 6 days	CCGTTCAATTGGTACAAAGCTGG	PDK1	ENSG00000152256	-1.004367515529495	[1333]	[197,52]	-5	hSpCas9	negative selection	1797068
172564563	172564586	2	-	26627737	HCT116	viability after 6 days	CCTTGTATTCAATCACACCCTGG	PDK1	ENSG00000152256	-0.1995050889309135	[661]	[40,117]	-1	hSpCas9	negative selection	1797069
172568748	172568771	2	+	26627737	HCT116	viability after 6 days	ACCAGGACAGCCAATACAAGTGG	PDK1	ENSG00000152256	-0.15089028983697284	[1548]	[364,138]	-1	hSpCas9	negative selection	1797070
172586372	172586395	2	-	26627737	HCT116	viability after 6 days	ACATACCAGAGGCACTGCGCGGG	PDK1	ENSG00000152256	1.81650941183336	[562]	[352,288]	8	hSpCas9	negative selection	1797071
172595859	172595882	2	-	26627737	HCT116	viability after 6 days	CAGGCAGCTTTGTTATACACTGG	PDK1	ENSG00000152256	0.20515246241525154	[784]	[285,62]	1	hSpCas9	negative selection	1797072
172556282	172556305	2	-	26627737	HCT116	viability after 8 days	AGCGCGCGTAGAAGTCCACCTGG	PDK1	ENSG00000152256	0.7868053237861796	[74]	[60,104,47]	7	hSpCas9	negative selection	1879382
172558828	172558851	2	+	26627737	HCT116	viability after 8 days	CCGTTCAATTGGTACAAAGCTGG	PDK1	ENSG00000152256	0.05835212341660556	[614]	[351,469,237]	0	hSpCas9	negative selection	1879383
172564563	172564586	2	-	26627737	HCT116	viability after 8 days	CCTTGTATTCAATCACACCCTGG	PDK1	ENSG00000152256	0.1550584762074857	[336]	[182,157,277]	1	hSpCas9	negative selection	1879384
172568748	172568771	2	+	26627737	HCT116	viability after 8 days	ACCAGGACAGCCAATACAAGTGG	PDK1	ENSG00000152256	-0.13481468239677286	[541]	[259,215,338]	-1	hSpCas9	negative selection	1879385
172586372	172586395	2	-	26627737	HCT116	viability after 8 days	ACATACCAGAGGCACTGCGCGGG	PDK1	ENSG00000152256	-0.018959734776865023	[392]	[216,190,232]	0	hSpCas9	negative selection	1879386
172595859	172595882	2	-	26627737	HCT116	viability after 8 days	CAGGCAGCTTTGTTATACACTGG	PDK1	ENSG00000152256	0.0847301744688459	[510]	[399,311,186]	1	hSpCas9	negative selection	1879387
172556282	172556305	2	-	26627737	HCT116	viability after 9 days	AGCGCGCGTAGAAGTCCACCTGG	PDK1	ENSG00000152256	0.1108051276079578	[194]	[96,23]	0	hSpCas9	negative selection	1961697
172558828	172558851	2	+	26627737	HCT116	viability after 9 days	CCGTTCAATTGGTACAAAGCTGG	PDK1	ENSG00000152256	1.1410715083704288	[1333]	[717,838]	7	hSpCas9	negative selection	1961698
172564563	172564586	2	-	26627737	HCT116	viability after 9 days	CCTTGTATTCAATCACACCCTGG	PDK1	ENSG00000152256	-0.3516270163599002	[661]	[80,183]	-2	hSpCas9	negative selection	1961699
172568748	172568771	2	+	26627737	HCT116	viability after 9 days	ACCAGGACAGCCAATACAAGTGG	PDK1	ENSG00000152256	-0.1478459157018699	[1548]	[622,175]	-1	hSpCas9	negative selection	1961700
172586372	172586395	2	-	26627737	HCT116	viability after 9 days	ACATACCAGAGGCACTGCGCGGG	PDK1	ENSG00000152256	1.0898455590446763	[562]	[467,202]	7	hSpCas9	negative selection	1961701
172595859	172595882	2	-	26627737	HCT116	viability after 9 days	CAGGCAGCTTTGTTATACACTGG	PDK1	ENSG00000152256	0.16002713386927325	[784]	[279,197]	1	hSpCas9	negative selection	1961702
172556282	172556305	2	-	26627737	HCT116	viability after 12 days	AGCGCGCGTAGAAGTCCACCTGG	PDK1	ENSG00000152256	0.21596241717883835	[74]	[72,47,13]	2	hSpCas9	negative selection	2044012
172558828	172558851	2	+	26627737	HCT116	viability after 12 days	CCGTTCAATTGGTACAAAGCTGG	PDK1	ENSG00000152256	0.30454757513766273	[614]	[232,560,421]	3	hSpCas9	negative selection	2044013
172564563	172564586	2	-	26627737	HCT116	viability after 12 days	CCTTGTATTCAATCACACCCTGG	PDK1	ENSG00000152256	0.0868633183047886	[336]	[179,105,276]	0	hSpCas9	negative selection	2044014
172568748	172568771	2	+	26627737	HCT116	viability after 12 days	ACCAGGACAGCCAATACAAGTGG	PDK1	ENSG00000152256	-0.7219360632303423	[541]	[212,191,109]	-7	hSpCas9	negative selection	2044015
172586372	172586395	2	-	26627737	HCT116	viability after 12 days	ACATACCAGAGGCACTGCGCGGG	PDK1	ENSG00000152256	0.15649114652801904	[392]	[232,174,280]	1	hSpCas9	negative selection	2044016
172595859	172595882	2	-	26627737	HCT116	viability after 12 days	CAGGCAGCTTTGTTATACACTGG	PDK1	ENSG00000152256	0.032226603778207075	[510]	[286,243,290]	0	hSpCas9	negative selection	2044017
172556282	172556305	2	-	26627737	HCT116	viability after 15 days	AGCGCGCGTAGAAGTCCACCTGG	PDK1	ENSG00000152256	0.11345095600551058	[74]	[57,21,60]	1	hSpCas9	negative selection	2126327
172558828	172558851	2	+	26627737	HCT116	viability after 15 days	CCGTTCAATTGGTACAAAGCTGG	PDK1	ENSG00000152256	0.12972945723474627	[614]	[297,587,263]	1	hSpCas9	negative selection	2126328
172564563	172564586	2	-	26627737	HCT116	viability after 15 days	CCTTGTATTCAATCACACCCTGG	PDK1	ENSG00000152256	0.42701719536550237	[336]	[247,94,433]	4	hSpCas9	negative selection	2126329
172568748	172568771	2	+	26627737	HCT116	viability after 15 days	ACCAGGACAGCCAATACAAGTGG	PDK1	ENSG00000152256	-0.1813677650779959	[541]	[259,226,333]	-2	hSpCas9	negative selection	2126330
172586372	172586395	2	-	26627737	HCT116	viability after 15 days	ACATACCAGAGGCACTGCGCGGG	PDK1	ENSG00000152256	-0.4871139764688858	[392]	[196,91,197]	-5	hSpCas9	negative selection	2126331
172595859	172595882	2	-	26627737	HCT116	viability after 15 days	CAGGCAGCTTTGTTATACACTGG	PDK1	ENSG00000152256	0.07653665189255532	[510]	[285,287,350]	0	hSpCas9	negative selection	2126332
172556282	172556305	2	-	26627737	HCT116	viability after 18 days	AGCGCGCGTAGAAGTCCACCTGG	PDK1	ENSG00000152256	1.0377822572440705	[74]	[120,40,62]	7	hSpCas9	negative selection	2208642
172558828	172558851	2	+	26627737	HCT116	viability after 18 days	CCGTTCAATTGGTACAAAGCTGG	PDK1	ENSG00000152256	-0.27772525771361745	[614]	[222,320,183]	-3	hSpCas9	negative selection	2208643
172564563	172564586	2	-	26627737	HCT116	viability after 18 days	CCTTGTATTCAATCACACCCTGG	PDK1	ENSG00000152256	0.43451928161934655	[336]	[163,110,400]	4	hSpCas9	negative selection	2208644
172568748	172568771	2	+	26627737	HCT116	viability after 18 days	ACCAGGACAGCCAATACAAGTGG	PDK1	ENSG00000152256	0.0781642829261241	[541]	[213,283,333]	0	hSpCas9	negative selection	2208645
172586372	172586395	2	-	26627737	HCT116	viability after 18 days	ACATACCAGAGGCACTGCGCGGG	PDK1	ENSG00000152256	-0.17606730142538204	[392]	[111,186,205]	-2	hSpCas9	negative selection	2208646
172595859	172595882	2	-	26627737	HCT116	viability after 18 days	CAGGCAGCTTTGTTATACACTGG	PDK1	ENSG00000152256	-0.022339941174170708	[510]	[377,219,127]	0	hSpCas9	negative selection	2208647
172556138	172556161	2	+	24336569	HL60	viability	AGCGGGACTCGGCATGAGGCTGG	PDK1	ENSG00000152256	0.26513344709957926	[660]	[1680]	2	hSpCas9	negative selection	2283333
172556143	172556166	2	+	24336569	HL60	viability	GACTCGGCATGAGGCTGGCGCGG	PDK1	ENSG00000152256	0.23297917829544512	[1545]	[3844]	2	hSpCas9	negative selection	2283334
172556154	172556177	2	+	24336569	HL60	viability	AGGCTGGCGCGGCTGCTTCGCGG	PDK1	ENSG00000152256	0.5707717547618015	[411]	[1294]	5	hSpCas9	negative selection	2283335
172556165	172556188	2	+	24336569	HL60	viability	GCTGCTTCGCGGAGCCGCCTTGG	PDK1	ENSG00000152256	1.3614492992586973	[550]	[2995]	8	hSpCas9	negative selection	2283336
172556212	172556235	2	-	24336569	HL60	viability	GAAGCTGCGGCTGAAGCCGGCGG	PDK1	ENSG00000152256	1.5034984000922598	[251]	[1511]	8	hSpCas9	negative selection	2283337
172556225	172556248	2	+	24336569	HL60	viability	CCGCAGCTTCAGCTCGGACTCGG	PDK1	ENSG00000152256	0.5411872709734928	[402]	[1240]	5	hSpCas9	negative selection	2283338
172556237	172556260	2	+	24336569	HL60	viability	CTCGGACTCGGGCTCCAGCCCGG	PDK1	ENSG00000152256	1.1687625289042773	[329]	[1569]	8	hSpCas9	negative selection	2283339
172556250	172556273	2	+	24336569	HL60	viability	TCCAGCCCGGCGTCCGAGCGCGG	PDK1	ENSG00000152256	0.5768715864224792	[459]	[1451]	5	hSpCas9	negative selection	2283340
172556255	172556278	2	-	24336569	HL60	viability	GAACGCCGCGCTCGGACGCCGGG	PDK1	ENSG00000152256	1.2767020221100616	[400]	[2055]	8	hSpCas9	negative selection	2283341
172556263	172556286	2	-	24336569	HL60	viability	CTGGCCCGGAACGCCGCGCTCGG	PDK1	ENSG00000152256	-0.7895238183487252	[699]	[856]	-6	hSpCas9	negative selection	2283342
172556138	172556161	2	+	24336569	KBM7	viability	AGCGGGACTCGGCATGAGGCTGG	PDK1	ENSG00000152256	0.6000102619693778	[409]	[1694]	5	hSpCas9	negative selection	2350510
172556143	172556166	2	+	24336569	KBM7	viability	GACTCGGCATGAGGCTGGCGCGG	PDK1	ENSG00000152256	0.3987508178034298	[865]	[3113]	3	hSpCas9	negative selection	2350511
172556154	172556177	2	+	24336569	KBM7	viability	AGGCTGGCGCGGCTGCTTCGCGG	PDK1	ENSG00000152256	0.8127466486700388	[310]	[1489]	7	hSpCas9	negative selection	2350512
172556165	172556188	2	+	24336569	KBM7	viability	GCTGCTTCGCGGAGCCGCCTTGG	PDK1	ENSG00000152256	0.9911692563933447	[478]	[2596]	8	hSpCas9	negative selection	2350513
172556212	172556235	2	-	24336569	KBM7	viability	GAAGCTGCGGCTGAAGCCGGCGG	PDK1	ENSG00000152256	0.09838917255641007	[349]	[1021]	0	hSpCas9	negative selection	2350514
172556225	172556248	2	+	24336569	KBM7	viability	CCGCAGCTTCAGCTCGGACTCGG	PDK1	ENSG00000152256	0.05806085151086804	[566]	[1609]	0	hSpCas9	negative selection	2350515
172556237	172556260	2	+	24336569	KBM7	viability	CTCGGACTCGGGCTCCAGCCCGG	PDK1	ENSG00000152256	0.9444901913215233	[276]	[1453]	7	hSpCas9	negative selection	2350516
172556250	172556273	2	+	24336569	KBM7	viability	TCCAGCCCGGCGTCCGAGCGCGG	PDK1	ENSG00000152256	0.012418443820996217	[694]	[1911]	0	hSpCas9	negative selection	2350517
172556255	172556278	2	-	24336569	KBM7	viability	GAACGCCGCGCTCGGACGCCGGG	PDK1	ENSG00000152256	1.0552822239573798	[469]	[2663]	8	hSpCas9	negative selection	2350518
172556263	172556286	2	-	24336569	KBM7	viability	CTGGCCCGGAACGCCGCGCTCGG	PDK1	ENSG00000152256	0.42914942854938376	[347]	[1277]	4	hSpCas9	negative selection	2350519
172555771	172555794	2	-	25494202	A375	resistance to PLX-4720 (puromycin)	ATGGGACTGGGGACACTAAGAGG	PDK1	ENSG00000152256	0.14516284090865084	[152,142]	[44,24]	0	dCas9-VP64	positive selection	2430720
172555830	172555853	2	-	25494202	A375	resistance to PLX-4720 (puromycin)	CCGCCCCAGCCGGCGAGGTGTGG	PDK1	ENSG00000152256	0.1912109445538837	[152,2]	[35,0]	0	dCas9-VP64	positive selection	2430721
172555797	172555820	2	-	25494202	A375	resistance to PLX-4720 (puromycin)	TCGGCCGTCCCCGTACACGTCGG	PDK1	ENSG00000152256	0.14498397848546318	[423,138]	[79,54]	0	dCas9-VP64	positive selection	2430722
172581116	172581139	2	+	25494202	A375	resistance to PLX-4720 (puromycin)	GGAGTCTCCCTCTGTTGCCCAGG	PDK1	ENSG00000152256	2.420787887415494	[28,17]	[7,46]	7	dCas9-VP64	positive selection	2430928
172555771	172555794	2	-	25494202	A375	resistance to PLX-4720 (zeocin)	ATGGGACTGGGGACACTAAGAGG	PDK1	ENSG00000152256	-0.12127123175033772	[257,293]	[117,49]	-1	dCas9-VP64	positive selection	2525975
172555830	172555853	2	-	25494202	A375	resistance to PLX-4720 (zeocin)	CCGCCCCAGCCGGCGAGGTGTGG	PDK1	ENSG00000152256	4.935528845499924	[23,39]	[8,616]	9	dCas9-VP64	positive selection	2525976
172555797	172555820	2	-	25494202	A375	resistance to PLX-4720 (zeocin)	TCGGCCGTCCCCGTACACGTCGG	PDK1	ENSG00000152256	0.8444308351634423	[29,90]	[15,52]	5	dCas9-VP64	positive selection	2525977
172581116	172581139	2	+	25494202	A375	resistance to PLX-4720 (zeocin)	GGAGTCTCCCTCTGTTGCCCAGG	PDK1	ENSG00000152256	0.2582242437662712	[17,52]	[13,12]	2	dCas9-VP64	positive selection	2526183
172564579	172564602	2	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	ATACAAGGAGAGCTTTGGGGTGG	PDK1	ENSG00000152256	-0.1502537196291266	[5,5]	[3,3]	-2	hSpCas9	positive selection	3010497
172558828	172558851	2	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CCAGCTTTGTACCAATTGAACGG	PDK1	ENSG00000152256	0.20210426577981977	[5,5]	[5,5]	4	hSpCas9	positive selection	3010498
172565011	172565034	2	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CCATCTCATCGAAAACACATTGG	PDK1	ENSG00000152256	0.1250546678155976	[5,5]	[4,5]	2	hSpCas9	positive selection	3010499
172564984	172565007	2	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TTGTTTGGTGGAAAAGGCAAAGG	PDK1	ENSG00000152256	0.2847354310812816	[3,4]	[4,4]	6	hSpCas9	positive selection	3010500
172564579	172564602	2	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	ATACAAGGAGAGCTTTGGGGTGG	PDK1	ENSG00000152256	-0.020337845280166522	[5,5]	[4,2]	0	hSpCas9	positive selection	3078355
172558828	172558851	2	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CCAGCTTTGTACCAATTGAACGG	PDK1	ENSG00000152256	0.3872572929808923	[5,5]	[4,5]	6	hSpCas9	positive selection	3078356
172565011	172565034	2	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CCATCTCATCGAAAACACATTGG	PDK1	ENSG00000152256	0.295652276376975	[5,5]	[5,4]	5	hSpCas9	positive selection	3078357
172564984	172565007	2	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TTGTTTGGTGGAAAAGGCAAAGG	PDK1	ENSG00000152256	-0.30089068925073603	[3,3]	[2,1]	-4	hSpCas9	positive selection	3078358
172565010	172565033		-	24336571	A375	resistance to PLX after 7 days	CCAATGTGTTTTCGATGAGATGG	PDK1	ENSG00000152256	-0.1327476095794508	[9,8]	[8,7]	-4	hSpCas9	positive selection	3134742
172558828	172558851		-	24336571	A375	resistance to PLX after 7 days	CCAGCTTTGTACCAATTGAACGG	PDK1	ENSG00000152256	-0.1552613121646888	[9,9]	[7,8]	-5	hSpCas9	positive selection	3134743
172565010	172565033		+	24336571	A375	resistance to PLX after 7 days	CCATCTCATCGAAAACACATTGG	PDK1	ENSG00000152256	-0.4550123814530243	[11,8]	[7,7]	-9	hSpCas9	positive selection	3134744
172558828	172558851		+	24336571	A375	resistance to PLX after 7 days	CCGTTCAATTGGTACAAAGCTGG	PDK1	ENSG00000152256	0.011125104174939504	[7,8]	[7,8]	0	hSpCas9	positive selection	3134745
172558732	172558755		-	24336571	A375	resistance to PLX after 7 days	TTGCCGCAGAAACATAAATGAGG	PDK1	ENSG00000152256	-0.3420063567538584	[8,10]	[8,6]	-8	hSpCas9	positive selection	3134746
172565010	172565033		-	24336571	A375	resistance to PLX after 14 days	CCAATGTGTTTTCGATGAGATGG	PDK1	ENSG00000152256	1.3237338845391833	[8,4]	[5,10]	8	hSpCas9	positive selection	3192535
172558828	172558851		-	24336571	A375	resistance to PLX after 14 days	CCAGCTTTGTACCAATTGAACGG	PDK1	ENSG00000152256	-0.3440011890766035	[9,14]	[4,3]	-4	hSpCas9	positive selection	3192536
172565010	172565033		+	24336571	A375	resistance to PLX after 14 days	CCATCTCATCGAAAACACATTGG	PDK1	ENSG00000152256	-0.3191119696443998	[7,8]	[2,2]	-4	hSpCas9	positive selection	3192537
172558828	172558851		+	24336571	A375	resistance to PLX after 14 days	CCGTTCAATTGGTACAAAGCTGG	PDK1	ENSG00000152256	0.3689908194767897	[6,9]	[4,4]	3	hSpCas9	positive selection	3192538
172558732	172558755		-	24336571	A375	resistance to PLX after 14 days	TTGCCGCAGAAACATAAATGAGG	PDK1	ENSG00000152256	-0.9709230741729089	[13,11]	[2,1]	-9	hSpCas9	positive selection	3192539
172565010	172565033		-	24336571	A375	viability after 7 days	CCAATGTGTTTTCGATGAGATGG	PDK1	ENSG00000152256	0.1769574918312899	[8]	[9,8]	2	hSpCas9	negative selection	3250328
172558828	172558851		-	24336571	A375	viability after 7 days	CCAGCTTTGTACCAATTGAACGG	PDK1	ENSG00000152256	-0.5718097216619658	[14]	[9,9]	-7	hSpCas9	negative selection	3250329
172565010	172565033		+	24336571	A375	viability after 7 days	CCATCTCATCGAAAACACATTGG	PDK1	ENSG00000152256	-0.39805796282087713	[14]	[11,8]	-5	hSpCas9	negative selection	3250330
172558828	172558851		+	24336571	A375	viability after 7 days	CCGTTCAATTGGTACAAAGCTGG	PDK1	ENSG00000152256	-0.4319276037727914	[11]	[7,8]	-6	hSpCas9	negative selection	3250331
172558732	172558755		-	24336571	A375	viability after 7 days	TTGCCGCAGAAACATAAATGAGG	PDK1	ENSG00000152256	-0.01737928599115074	[10]	[8,10]	0	hSpCas9	negative selection	3250332
172565010	172565033		-	24336571	A375	viability after 14 days	CCAATGTGTTTTCGATGAGATGG	PDK1	ENSG00000152256	-0.11757437034266316	[8]	[8,4]	-1	hSpCas9	negative selection	3308121
172558828	172558851		-	24336571	A375	viability after 14 days	CCAGCTTTGTACCAATTGAACGG	PDK1	ENSG00000152256	-0.1479659252219513	[14]	[9,14]	-2	hSpCas9	negative selection	3308122
172565010	172565033		+	24336571	A375	viability after 14 days	CCATCTCATCGAAAACACATTGG	PDK1	ENSG00000152256	-0.6513641863860111	[14]	[7,8]	-7	hSpCas9	negative selection	3308123
172558828	172558851		+	24336571	A375	viability after 14 days	CCGTTCAATTGGTACAAAGCTGG	PDK1	ENSG00000152256	-0.4748046062083817	[11]	[6,9]	-5	hSpCas9	negative selection	3308124
172558732	172558755		-	24336571	A375	viability after 14 days	TTGCCGCAGAAACATAAATGAGG	PDK1	ENSG00000152256	0.33286723638020477	[10]	[13,11]	4	hSpCas9	negative selection	3308125
172565043	172565066	2	-	27383988	293T	resistance to West Nile virus (flavivirus)	ACTTCAAGTACATTGCAGTTTGG	PDK1	ENSG00000152256	0.20204377594464537	[132,132]	[0,0]	1	hSpCas9	positive selection	3385213
172566853	172566876	2	+	27383988	293T	resistance to West Nile virus (flavivirus)	TAGATGGCTATGAAAATGCTAGG	PDK1	ENSG00000152256	0.4499712893882311	[111,111]	[0,0]	2	hSpCas9	positive selection	3385214
172566907	172566930	2	-	27383988	293T	resistance to West Nile virus (flavivirus)	TAGTTCTTCAAGTTCTAGTTCGG	PDK1	ENSG00000152256	-1.3973098170821323	[402,402]	[0,0]	-8	hSpCas9	positive selection	3385215
172564578	172564601	2	+	26780180	HT29	viability (Avana library 4 designs)	ATACAAGGAGAGCTTTGGGGTGG	PDK1	ENSG00000152256	2.47591851648244	[]	[]	8	hSpCas9	negative selection	3448554
172558828	172558851	2	-	26780180	HT29	viability (Avana library 4 designs)	CCAGCTTTGTACCAATTGAACGG	PDK1	ENSG00000152256	-0.561287141531735	[]	[]	-7	hSpCas9	negative selection	3448555
172565010	172565033	2	+	26780180	HT29	viability (Avana library 4 designs)	CCATCTCATCGAAAACACATTGG	PDK1	ENSG00000152256	-0.421581375227842	[]	[]	-6	hSpCas9	negative selection	3448556
172564983	172565006	2	+	26780180	HT29	viability (Avana library 4 designs)	TTGTTTGGTGGAAAAGGCAAAGG	PDK1	ENSG00000152256	0.717985097474717	[]	[]	2	hSpCas9	negative selection	3448557
172558828	172558851	2	-	26780180	A375	viability (Avana lentiCRISPRv2)	CCAGCTTTGTACCAATTGAACGG	PDK1	ENSG00000152256	-0.806048508812315	[]	[]	-1	hSpCas9	negative selection	3542890
172564578	172564601	2	+	26780180	A375	viability (Avana lentiCRISPRv2)	ATACAAGGAGAGCTTTGGGGTGG	PDK1	ENSG00000152256	1.01735686968201	[]	[]	1	hSpCas9	negative selection	3542891
172565010	172565033	2	+	26780180	A375	viability (Avana lentiCRISPRv2)	CCATCTCATCGAAAACACATTGG	PDK1	ENSG00000152256	-3.7182309055723	[]	[]	-4	hSpCas9	negative selection	3542892
172564983	172565006	2	+	26780180	A375	viability (Avana lentiCRISPRv2)	TTGTTTGGTGGAAAAGGCAAAGG	PDK1	ENSG00000152256	2.67993669325883	[]	[]	4	hSpCas9	negative selection	3542893
172556219	172556242	2	+	26780180	A375	viability (Avana lentiCRISPRv2)	CTTCAGCCGCAGCTTCAGCTCGG	PDK1	ENSG00000152256	0.60612144782733	[]	[]	0	hSpCas9	negative selection	3542894
172556143	172556166	2	+	26780180	A375	viability (Avana lentiCRISPRv2)	GACTCGGCATGAGGCTGGCGCGG	PDK1	ENSG00000152256	4.24537621186907	[]	[]	7	hSpCas9	negative selection	3542895
172558828	172558851	2	-	26780180	A375	viability (Avana lentiGuide)	CCAGCTTTGTACCAATTGAACGG	PDK1	ENSG00000152256	-5.3484326577633	[]	[]	-8	hSpCas9	negative selection	3651549
172564578	172564601	2	+	26780180	A375	viability (Avana lentiGuide)	ATACAAGGAGAGCTTTGGGGTGG	PDK1	ENSG00000152256	8.26739323742053	[]	[]	6	hSpCas9	negative selection	3651550
172565010	172565033	2	+	26780180	A375	viability (Avana lentiGuide)	CCATCTCATCGAAAACACATTGG	PDK1	ENSG00000152256	-3.78884492951457	[]	[]	-6	hSpCas9	negative selection	3651551
172564983	172565006	2	+	26780180	A375	viability (Avana lentiGuide)	TTGTTTGGTGGAAAAGGCAAAGG	PDK1	ENSG00000152256	1.50435281141596	[]	[]	1	hSpCas9	negative selection	3651552
172556219	172556242	2	+	26780180	A375	viability (Avana lentiGuide)	CTTCAGCCGCAGCTTCAGCTCGG	PDK1	ENSG00000152256	-1.36792267162655	[]	[]	-2	hSpCas9	negative selection	3651553
172556143	172556166	2	+	26780180	A375	viability (Avana lentiGuide)	GACTCGGCATGAGGCTGGCGCGG	PDK1	ENSG00000152256	-2.7012278178161	[]	[]	-5	hSpCas9	negative selection	3651554
172558828	172558851	2	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CCAGCTTTGTACCAATTGAACGG	PDK1	ENSG00000152256	-0.08913643763909704	[6]	[6,4]	-1	hSpCas9	positive selection	3760208
172564578	172564601	2	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ATACAAGGAGAGCTTTGGGGTGG	PDK1	ENSG00000152256	-0.15617009901038487	[6]	[5,5]	-3	hSpCas9	positive selection	3760209
172565010	172565033	2	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CCATCTCATCGAAAACACATTGG	PDK1	ENSG00000152256	-0.28370089036685203	[6]	[4,4]	-4	hSpCas9	positive selection	3760210
172564983	172565006	2	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TTGTTTGGTGGAAAAGGCAAAGG	PDK1	ENSG00000152256	0.09725740733576793	[5]	[6,5]	2	hSpCas9	positive selection	3760211
172556219	172556242	2	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CTTCAGCCGCAGCTTCAGCTCGG	PDK1	ENSG00000152256	0.15021040444476902	[4]	[5,4]	4	hSpCas9	positive selection	3760212
172556143	172556166	2	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GACTCGGCATGAGGCTGGCGCGG	PDK1	ENSG00000152256	0.34647759562893715	[4]	[5,4]	9	hSpCas9	positive selection	3760213
172558828	172558851	2	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CCAGCTTTGTACCAATTGAACGG	PDK1	ENSG00000152256	0.3108504597242803	[6]	[7,7]	8	hSpCas9	positive selection	3868815
172564578	172564601	2	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ATACAAGGAGAGCTTTGGGGTGG	PDK1	ENSG00000152256	-0.5393289408747338	[7]	[6,1]	-6	hSpCas9	positive selection	3868816
172565010	172565033	2	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CCATCTCATCGAAAACACATTGG	PDK1	ENSG00000152256	0.2573358153488864	[7]	[7,7]	7	hSpCas9	positive selection	3868817
172564983	172565006	2	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TTGTTTGGTGGAAAAGGCAAAGG	PDK1	ENSG00000152256	0.1371047237491549	[5]	[5,5]	3	hSpCas9	positive selection	3868818
172556219	172556242	2	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CTTCAGCCGCAGCTTCAGCTCGG	PDK1	ENSG00000152256	0.06156563112426402	[5]	[4,5]	1	hSpCas9	positive selection	3868819
172556143	172556166	2	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GACTCGGCATGAGGCTGGCGCGG	PDK1	ENSG00000152256	-0.08839071694976144	[4]	[4,3]	-1	hSpCas9	positive selection	3868820
172565043	172565066	2	-	26780180	A375	viability	ACTTCAAGTACATTGCAGTTTGG	PDK1	ENSG00000152256	0.570855633826409	[]	[]	1	hSpCas9	negative selection	3979588
172565010	172565033	2	+	26780180	A375	viability	CCATCTCATCGAAAACACATTGG	PDK1	ENSG00000152256	0.360032238175629	[]	[]	0	hSpCas9	negative selection	3979589
172558828	172558851	2	+	26780180	A375	viability	CCGTTCAATTGGTACAAAGCTGG	PDK1	ENSG00000152256	1.24925578348603	[]	[]	6	hSpCas9	negative selection	3979590
172558803	172558826	2	-	26780180	A375	viability	GGTGTCCTGAGAAGATTATCTGG	PDK1	ENSG00000152256	1.21436259568544	[]	[]	6	hSpCas9	negative selection	3979591
172566853	172566876	2	+	26780180	A375	viability	TAGATGGCTATGAAAATGCTAGG	PDK1	ENSG00000152256	1.49268330476002	[]	[]	8	hSpCas9	negative selection	3979592
172566907	172566930	2	-	26780180	A375	viability	TAGTTCTTCAAGTTCTAGTTCGG	PDK1	ENSG00000152256	0.153376070014166	[]	[]	0	hSpCas9	negative selection	3979593
172565043	172565066	2	-	26780180	HT29	viability (GeCKOv2 library)	ACTTCAAGTACATTGCAGTTTGG	PDK1	ENSG00000152256	0.501928014296506	[]	[]	1	hSpCas9	negative selection	4087554
172565010	172565033	2	+	26780180	HT29	viability (GeCKOv2 library)	CCATCTCATCGAAAACACATTGG	PDK1	ENSG00000152256	0.838540910333482	[]	[]	3	hSpCas9	negative selection	4087555
172558828	172558851	2	+	26780180	HT29	viability (GeCKOv2 library)	CCGTTCAATTGGTACAAAGCTGG	PDK1	ENSG00000152256	1.68852452381825	[]	[]	8	hSpCas9	negative selection	4087556
172558803	172558826	2	-	26780180	HT29	viability (GeCKOv2 library)	GGTGTCCTGAGAAGATTATCTGG	PDK1	ENSG00000152256	1.34787127964771	[]	[]	7	hSpCas9	negative selection	4087557
172566853	172566876	2	+	26780180	HT29	viability (GeCKOv2 library)	TAGATGGCTATGAAAATGCTAGG	PDK1	ENSG00000152256	0.507823887942773	[]	[]	1	hSpCas9	negative selection	4087558
172566907	172566930	2	-	26780180	HT29	viability (GeCKOv2 library)	TAGTTCTTCAAGTTCTAGTTCGG	PDK1	ENSG00000152256	0.329604461468858	[]	[]	0	hSpCas9	negative selection	4087559
172565010	172565033	2	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CCAATGTGTTTTCGATGAGATGG	PDK1	ENSG00000152256	0.1774343569031642	[3]	[1,2]	4	hSpCas9	positive selection	4159648
172558828	172558851	2	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CCAGCTTTGTACCAATTGAACGG	PDK1	ENSG00000152256	0.28101726440334973	[3]	[3,1]	7	hSpCas9	positive selection	4159649
172565010	172565033	2	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CCATCTCATCGAAAACACATTGG	PDK1	ENSG00000152256	-0.015487509332381508	[3]	[3,1]	0	hSpCas9	positive selection	4159650
172558828	172558851	2	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CCGTTCAATTGGTACAAAGCTGG	PDK1	ENSG00000152256	-0.051827790983904165	[3]	[1,2]	-1	hSpCas9	positive selection	4159651
172558732	172558755	2	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TTGCCGCAGAAACATAAATGAGG	PDK1	ENSG00000152256	0.11140203995987909	[3]	[3,1]	3	hSpCas9	positive selection	4159652
172565010	172565033	2	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CCAATGTGTTTTCGATGAGATGG	PDK1	ENSG00000152256	0.2788416338551619	[1]	[0,0,0,0]	2	hSpCas9	positive selection	4223670
172558828	172558851	2	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CCAGCTTTGTACCAATTGAACGG	PDK1	ENSG00000152256	0.256729994623917	[3]	[3,2,1,0]	2	hSpCas9	positive selection	4223671
172565010	172565033	2	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CCATCTCATCGAAAACACATTGG	PDK1	ENSG00000152256	1.1001274098923548	[5]	[5,3,2,5]	8	hSpCas9	positive selection	4223672
172558828	172558851	2	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CCGTTCAATTGGTACAAAGCTGG	PDK1	ENSG00000152256	1.53776761157742	[2]	[2,2,2,4]	9	hSpCas9	positive selection	4223673
172558732	172558755	2	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TTGCCGCAGAAACATAAATGAGG	PDK1	ENSG00000152256	0.5158494240872474	[3]	[0,0,0,3]	3	hSpCas9	positive selection	4223674
172558828	172558851	2	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCGTTCAATTGGTACAAAGCTGG	PDK1	ENSG00000152256	-0.11132776437593368	[3]	[3,1]	-2	hSpCas9	positive selection	4289544
172558803	172558826	2	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GGTGTCCTGAGAAGATTATCTGG	PDK1	ENSG00000152256	-0.20891049198554287	[2]	[2,0]	-4	hSpCas9	positive selection	4289545
172565010	172565033	2	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCATCTCATCGAAAACACATTGG	PDK1	ENSG00000152256	0.057482459915725925	[3]	[3,2]	1	hSpCas9	positive selection	4289546
172565043	172565066	2	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ACTTCAAGTACATTGCAGTTTGG	PDK1	ENSG00000152256	0.6949437870190396	[2]	[2,3]	9	hSpCas9	positive selection	4353796
172566853	172566876	2	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TAGATGGCTATGAAAATGCTAGG	PDK1	ENSG00000152256	0.32591954824735203	[2]	[4,1]	6	hSpCas9	positive selection	4353797
172566907	172566930	2	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TAGTTCTTCAAGTTCTAGTTCGG	PDK1	ENSG00000152256	0.5410810773641498	[3]	[4,4]	9	hSpCas9	positive selection	4353798
172556277	172556299	2	-	27760321	OCIAML3	viability	CGTAGAAGTCCACCTGGCCCGG	PDK1	ENSG00000152256	0.5010441355771286	[935,772]	[868,1035]	6	hSpCas9	negative selection	4426710
172558829	172558851	2	+	27760321	OCIAML3	viability	CGTTCAATTGGTACAAAGCTGG	PDK1	ENSG00000152256	-0.4238597886221793	[277,265]	[173,138]	-4	hSpCas9	negative selection	4426711
172564540	172564562	2	+	27760321	OCIAML3	viability	AATGATGTCATTCCCACAATGG	PDK1	ENSG00000152256	0.4687647636385992	[154,139]	[175,137]	5	hSpCas9	negative selection	4426712
172564610	172564632	2	-	27760321	OCIAML3	viability	AAGTACTGAACATTCTGGCTGG	PDK1	ENSG00000152256	0.15335905895220486	[559,486]	[379,550]	1	hSpCas9	negative selection	4426713
172565010	172565032	2	-	27760321	OCIAML3	viability	CAATGTGTTTTCGATGAGATGG	PDK1	ENSG00000152256	0.6106655787632264	[275,214]	[222,379]	7	hSpCas9	negative selection	4426714
172556277	172556299	2	-	27760321	OCIAML2	viability	CGTAGAAGTCCACCTGGCCCGG	PDK1	ENSG00000152256	0.41647952784509357	[935,772]	[775,1105]	5	hSpCas9	negative selection	4510173
172558829	172558851	2	+	27760321	OCIAML2	viability	CGTTCAATTGGTACAAAGCTGG	PDK1	ENSG00000152256	-0.6226054724934915	[277,265]	[124,166]	-6	hSpCas9	negative selection	4510174
172564540	172564562	2	+	27760321	OCIAML2	viability	AATGATGTCATTCCCACAATGG	PDK1	ENSG00000152256	0.1410999004189155	[154,139]	[146,110]	1	hSpCas9	negative selection	4510175
172564610	172564632	2	-	27760321	OCIAML2	viability	AAGTACTGAACATTCTGGCTGG	PDK1	ENSG00000152256	-0.2944029849553302	[559,486]	[274,435]	-4	hSpCas9	negative selection	4510176
172565010	172565032	2	-	27760321	OCIAML2	viability	CAATGTGTTTTCGATGAGATGG	PDK1	ENSG00000152256	0.29173060188151034	[275,214]	[199,295]	4	hSpCas9	negative selection	4510177
172556277	172556299	2	-	27760321	MV411	viability	CGTAGAAGTCCACCTGGCCCGG	PDK1	ENSG00000152256	1.1278105441882085	[935,772]	[1274,1153]	8	hSpCas9	negative selection	4593636
172558829	172558851	2	+	27760321	MV411	viability	CGTTCAATTGGTACAAAGCTGG	PDK1	ENSG00000152256	0.2192928114650169	[277,265]	[48,449]	1	hSpCas9	negative selection	4593637
172564540	172564562	2	+	27760321	MV411	viability	AATGATGTCATTCCCACAATGG	PDK1	ENSG00000152256	0.9592670731028147	[154,139]	[288,38]	7	hSpCas9	negative selection	4593638
172564610	172564632	2	-	27760321	MV411	viability	AAGTACTGAACATTCTGGCTGG	PDK1	ENSG00000152256	0.5014376639563897	[559,486]	[542,404]	3	hSpCas9	negative selection	4593639
172565010	172565032	2	-	27760321	MV411	viability	CAATGTGTTTTCGATGAGATGG	PDK1	ENSG00000152256	-2.060279680821062	[275,214]	[8,82]	-8	hSpCas9	negative selection	4593640
172556277	172556299	2	-	27760321	HL60	viability	CGTAGAAGTCCACCTGGCCCGG	PDK1	ENSG00000152256	0.6037238288416426	[935,772]	[1019,1093]	7	hSpCas9	negative selection	4677099
172558829	172558851	2	+	27760321	HL60	viability	CGTTCAATTGGTACAAAGCTGG	PDK1	ENSG00000152256	-0.8029278899292136	[277,265]	[128,125]	-7	hSpCas9	negative selection	4677100
172564540	172564562	2	+	27760321	HL60	viability	AATGATGTCATTCCCACAATGG	PDK1	ENSG00000152256	0.35146176598582723	[154,139]	[139,167]	4	hSpCas9	negative selection	4677101
172564610	172564632	2	-	27760321	HL60	viability	AAGTACTGAACATTCTGGCTGG	PDK1	ENSG00000152256	0.11670667998560669	[559,486]	[529,390]	1	hSpCas9	negative selection	4677102
172565010	172565032	2	-	27760321	HL60	viability	CAATGTGTTTTCGATGAGATGG	PDK1	ENSG00000152256	0.2426549049300325	[275,214]	[206,265]	3	hSpCas9	negative selection	4677103
172556277	172556299	2	-	27760321	HT1080	viability	CGTAGAAGTCCACCTGGCCCGG	PDK1	ENSG00000152256	1.3228109650705904	[772,602]	[655,717]	7	hSpCas9	negative selection	4760562
172558829	172558851	2	+	27760321	HT1080	viability	CGTTCAATTGGTACAAAGCTGG	PDK1	ENSG00000152256	-1.3253909585800172	[265,207]	[51,21]	-5	hSpCas9	negative selection	4760563
172564540	172564562	2	+	27760321	HT1080	viability	AATGATGTCATTCCCACAATGG	PDK1	ENSG00000152256	-0.15177960071348262	[139,108]	[36,52]	0	hSpCas9	negative selection	4760564
172564610	172564632	2	-	27760321	HT1080	viability	AAGTACTGAACATTCTGGCTGG	PDK1	ENSG00000152256	0.8016020944305389	[486,379]	[395,196]	4	hSpCas9	negative selection	4760565
172565010	172565032	2	-	27760321	HT1080	viability	CAATGTGTTTTCGATGAGATGG	PDK1	ENSG00000152256	0.16433303785730335	[214,167]	[95,73]	0	hSpCas9	negative selection	4760566
172556277	172556299	2	-	27760321	HT29	viability after 7 days	CGTAGAAGTCCACCTGGCCCGG	PDK1	ENSG00000152256	0.2936505641780609	[772,602]	[1226,1136,912]	4	hSpCas9	negative selection	4844025
172558829	172558851	2	+	27760321	HT29	viability after 7 days	CGTTCAATTGGTACAAAGCTGG	PDK1	ENSG00000152256	-0.28989760014969546	[265,207]	[97,254,368]	-4	hSpCas9	negative selection	4844026
172564540	172564562	2	+	27760321	HT29	viability after 7 days	AATGATGTCATTCCCACAATGG	PDK1	ENSG00000152256	0.40575227787600565	[139,108]	[131,236,253]	6	hSpCas9	negative selection	4844027
172564610	172564632	2	-	27760321	HT29	viability after 7 days	AAGTACTGAACATTCTGGCTGG	PDK1	ENSG00000152256	-0.20487899916636512	[486,379]	[439,590,414]	-3	hSpCas9	negative selection	4844028
172565010	172565032	2	-	27760321	HT29	viability after 7 days	CAATGTGTTTTCGATGAGATGG	PDK1	ENSG00000152256	0.009519060801512436	[214,167]	[231,293,215]	0	hSpCas9	negative selection	4844029
172556277	172556299	2	-	27760321	HT29	viability after 25 days	CGTAGAAGTCCACCTGGCCCGG	PDK1	ENSG00000152256	0.49548466877808295	[772,602]	[1011,1154,1168]	5	hSpCas9	negative selection	4927488
172558829	172558851	2	+	27760321	HT29	viability after 25 days	CGTTCAATTGGTACAAAGCTGG	PDK1	ENSG00000152256	-0.8731728249901007	[265,207]	[85,155,211]	-6	hSpCas9	negative selection	4927489
172564540	172564562	2	+	27760321	HT29	viability after 25 days	AATGATGTCATTCCCACAATGG	PDK1	ENSG00000152256	-0.02091961864560954	[139,108]	[139,143,135]	0	hSpCas9	negative selection	4927490
172564610	172564632	2	-	27760321	HT29	viability after 25 days	AAGTACTGAACATTCTGGCTGG	PDK1	ENSG00000152256	-0.2795027692826281	[486,379]	[505,317,391]	-3	hSpCas9	negative selection	4927491
172565010	172565032	2	-	27760321	HT29	viability after 25 days	CAATGTGTTTTCGATGAGATGG	PDK1	ENSG00000152256	0.2540434965272279	[214,167]	[222,283,279]	2	hSpCas9	negative selection	4927492
172556277	172556299	2	-	27760321	HT29	viability after 22 days	CGTAGAAGTCCACCTGGCCCGG	PDK1	ENSG00000152256	0.45297654971317125	[772,602]	[791,1507,972]	5	hSpCas9	negative selection	5010951
172558829	172558851	2	+	27760321	HT29	viability after 22 days	CGTTCAATTGGTACAAAGCTGG	PDK1	ENSG00000152256	-1.0923562638808146	[265,207]	[80,157,147]	-7	hSpCas9	negative selection	5010952
172564540	172564562	2	+	27760321	HT29	viability after 22 days	AATGATGTCATTCCCACAATGG	PDK1	ENSG00000152256	0.09138249653089336	[139,108]	[50,227,183]	0	hSpCas9	negative selection	5010953
172564610	172564632	2	-	27760321	HT29	viability after 22 days	AAGTACTGAACATTCTGGCTGG	PDK1	ENSG00000152256	-0.09916721575036908	[486,379]	[491,534,374]	-1	hSpCas9	negative selection	5010954
172565010	172565032	2	-	27760321	HT29	viability after 22 days	CAATGTGTTTTCGATGAGATGG	PDK1	ENSG00000152256	0.5289242768335343	[214,167]	[257,276,425]	6	hSpCas9	negative selection	5010955
172556277	172556299	2	-	27760321	HT29	viability after 19 days	CGTAGAAGTCCACCTGGCCCGG	PDK1	ENSG00000152256	0.48124780314953	[772,602]	[1047,1059,1177]	5	hSpCas9	negative selection	5094414
172558829	172558851	2	+	27760321	HT29	viability after 19 days	CGTTCAATTGGTACAAAGCTGG	PDK1	ENSG00000152256	-0.05156176478893615	[265,207]	[47,474,239]	0	hSpCas9	negative selection	5094415
172564540	172564562	2	+	27760321	HT29	viability after 19 days	AATGATGTCATTCCCACAATGG	PDK1	ENSG00000152256	-0.2937366278582594	[139,108]	[123,184,42]	-3	hSpCas9	negative selection	5094416
172564610	172564632	2	-	27760321	HT29	viability after 19 days	AAGTACTGAACATTCTGGCTGG	PDK1	ENSG00000152256	0.15722581098420751	[486,379]	[626,620,422]	1	hSpCas9	negative selection	5094417
172565010	172565032	2	-	27760321	HT29	viability after 19 days	CAATGTGTTTTCGATGAGATGG	PDK1	ENSG00000152256	0.4030708644095059	[214,167]	[226,207,421]	4	hSpCas9	negative selection	5094418
172556277	172556299	2	-	27760321	HT29	viability after 16 days	CGTAGAAGTCCACCTGGCCCGG	PDK1	ENSG00000152256	0.6695266082972349	[772,602]	[1479,1023,1197]	7	hSpCas9	negative selection	5177877
172558829	172558851	2	+	27760321	HT29	viability after 16 days	CGTTCAATTGGTACAAAGCTGG	PDK1	ENSG00000152256	-0.7823237485723304	[265,207]	[209,146,110]	-6	hSpCas9	negative selection	5177878
172564540	172564562	2	+	27760321	HT29	viability after 16 days	AATGATGTCATTCCCACAATGG	PDK1	ENSG00000152256	0.852640363959397	[139,108]	[102,343,290]	8	hSpCas9	negative selection	5177879
172564610	172564632	2	-	27760321	HT29	viability after 16 days	AAGTACTGAACATTCTGGCTGG	PDK1	ENSG00000152256	0.051102968376690594	[486,379]	[645,422,453]	0	hSpCas9	negative selection	5177880
172565010	172565032	2	-	27760321	HT29	viability after 16 days	CAATGTGTTTTCGATGAGATGG	PDK1	ENSG00000152256	0.07508233942495635	[214,167]	[361,109,220]	0	hSpCas9	negative selection	5177881
172556277	172556299	2	-	27760321	HT29	viability after 13 days	CGTAGAAGTCCACCTGGCCCGG	PDK1	ENSG00000152256	0.520576163439636	[772,602]	[1520,891,1027]	6	hSpCas9	negative selection	5261340
172558829	172558851	2	+	27760321	HT29	viability after 13 days	CGTTCAATTGGTACAAAGCTGG	PDK1	ENSG00000152256	-0.44265850282692343	[265,207]	[278,248,85]	-5	hSpCas9	negative selection	5261341
172564540	172564562	2	+	27760321	HT29	viability after 13 days	AATGATGTCATTCCCACAATGG	PDK1	ENSG00000152256	-0.2089791045428706	[139,108]	[113,121,137]	-2	hSpCas9	negative selection	5261342
172564610	172564632	2	-	27760321	HT29	viability after 13 days	AAGTACTGAACATTCTGGCTGG	PDK1	ENSG00000152256	0.012167145428278459	[486,379]	[639,457,427]	0	hSpCas9	negative selection	5261343
172565010	172565032	2	-	27760321	HT29	viability after 13 days	CAATGTGTTTTCGATGAGATGG	PDK1	ENSG00000152256	0.558090981027722	[214,167]	[371,261,345]	7	hSpCas9	negative selection	5261344
172556277	172556299	2	-	27760321	HT29	viability after 10 days	CGTAGAAGTCCACCTGGCCCGG	PDK1	ENSG00000152256	0.4840076135775657	[772,602]	[1236,1145,1218]	6	hSpCas9	negative selection	5344803
172558829	172558851	2	+	27760321	HT29	viability after 10 days	CGTTCAATTGGTACAAAGCTGG	PDK1	ENSG00000152256	-0.6608349687421002	[265,207]	[181,238,142]	-6	hSpCas9	negative selection	5344804
172564540	172564562	2	+	27760321	HT29	viability after 10 days	AATGATGTCATTCCCACAATGG	PDK1	ENSG00000152256	0.453890459646221	[139,108]	[262,177,196]	6	hSpCas9	negative selection	5344805
172564610	172564632	2	-	27760321	HT29	viability after 10 days	AAGTACTGAACATTCTGGCTGG	PDK1	ENSG00000152256	-0.40729098172736755	[486,379]	[497,241,477]	-5	hSpCas9	negative selection	5344806
172565010	172565032	2	-	27760321	HT29	viability after 10 days	CAATGTGTTTTCGATGAGATGG	PDK1	ENSG00000152256	-0.07795238726857934	[214,167]	[239,248,191]	-1	hSpCas9	negative selection	5344807
172556277	172556299	2	-	27760321	MOLM13	viability	CGTAGAAGTCCACCTGGCCCGG	PDK1	ENSG00000152256	0.8486407057186244	[935,772]	[766,946]	6	hSpCas9	negative selection	5428266
172558829	172558851	2	+	27760321	MOLM13	viability	CGTTCAATTGGTACAAAGCTGG	PDK1	ENSG00000152256	0.6499151970633434	[277,265]	[487,30]	4	hSpCas9	negative selection	5428267
172564540	172564562	2	+	27760321	MOLM13	viability	AATGATGTCATTCCCACAATGG	PDK1	ENSG00000152256	1.2865424769551637	[154,139]	[184,217]	8	hSpCas9	negative selection	5428268
172564610	172564632	2	-	27760321	MOLM13	viability	AAGTACTGAACATTCTGGCTGG	PDK1	ENSG00000152256	-0.3640765035056031	[559,486]	[155,290]	-2	hSpCas9	negative selection	5428269
172565010	172565032	2	-	27760321	MOLM13	viability	CAATGTGTTTTCGATGAGATGG	PDK1	ENSG00000152256	0.11478984333019682	[275,214]	[68,216]	0	hSpCas9	negative selection	5428270
172556403	172556426	2	+	27661255	K562	viability	GCCGCTGCCCCAGGCCGGGTCGG	PDK1	ENSG00000152256	0.03945515506866126	[456,392]	[405,301]	1	dCas9-KRAB	negative selection	5501016
172556475	172556498	2	-	27661255	K562	viability	GGAAGCACCTAAGGCGCTGGGGG	PDK1	ENSG00000152256	-0.10441538885299809	[1070,861]	[775,673]	-4	dCas9-KRAB	negative selection	5501017
172556503	172556526	2	-	27661255	K562	viability	GCCAGCGCCGGCACTTCGGAGGG	PDK1	ENSG00000152256	-0.16801932210144455	[511,498]	[405,319]	-5	dCas9-KRAB	negative selection	5501018
172558828	172558851	2	+	27260156	BXPC3	viability	CCGTTCAATTGGTACAAAGCTGG	PDK1	ENSG00000152256	-0.3342328916679946	[572]	[416,466,526,496]	-6	hSpCas9	negative selection	5562004
172558803	172558826	2	-	27260156	BXPC3	viability	GGTGTCCTGAGAAGATTATCTGG	PDK1	ENSG00000152256	0.0190972076793198	[408]	[314,381,525,537]	0	hSpCas9	negative selection	5562005
172565010	172565033	2	+	27260156	BXPC3	viability	CCATCTCATCGAAAACACATTGG	PDK1	ENSG00000152256	0.21004145284436637	[950]	[1135,990,1170,1327]	4	hSpCas9	negative selection	5562006
172565043	172565066	2	-	27260156	BXPC3	viability	ACTTCAAGTACATTGCAGTTTGG	PDK1	ENSG00000152256	0.2637809032061611	[250]	[329,363,244,312]	6	hSpCas9	negative selection	5626256
172566853	172566876	2	+	27260156	BXPC3	viability	TAGATGGCTATGAAAATGCTAGG	PDK1	ENSG00000152256	-0.13650581794718414	[417]	[361,378,434,419]	-3	hSpCas9	negative selection	5626257
172566907	172566930	2	-	27260156	BXPC3	viability	TAGTTCTTCAAGTTCTAGTTCGG	PDK1	ENSG00000152256	0.094426845219995	[780]	[819,696,968,1032]	2	hSpCas9	negative selection	5626258
172558828	172558851	2	+	27260156	A673	viability	CCGTTCAATTGGTACAAAGCTGG	PDK1	ENSG00000152256	-0.3383558609771962	[572]	[563,625,554,423]	-7	hSpCas9	negative selection	5683255
172558803	172558826	2	-	27260156	A673	viability	GGTGTCCTGAGAAGATTATCTGG	PDK1	ENSG00000152256	0.11653388325236264	[408]	[615,513,479,528]	2	hSpCas9	negative selection	5683256
172565010	172565033	2	+	27260156	A673	viability	CCATCTCATCGAAAACACATTGG	PDK1	ENSG00000152256	0.21353930322889014	[950]	[1372,1373,1180,1373]	5	hSpCas9	negative selection	5683257
172565043	172565066	2	-	27260156	A673	viability	ACTTCAAGTACATTGCAGTTTGG	PDK1	ENSG00000152256	-0.017326478277774116	[250]	[274,258,303,353]	0	hSpCas9	negative selection	5747507
172566853	172566876	2	+	27260156	A673	viability	TAGATGGCTATGAAAATGCTAGG	PDK1	ENSG00000152256	-0.2960608338801882	[417]	[464,396,435,338]	-6	hSpCas9	negative selection	5747508
172566907	172566930	2	-	27260156	A673	viability	TAGTTCTTCAAGTTCTAGTTCGG	PDK1	ENSG00000152256	0.15931083369756704	[780]	[1215,872,1084,1035]	4	hSpCas9	negative selection	5747509
172558828	172558851	2	+	27260156	A375	viability	CCGTTCAATTGGTACAAAGCTGG	PDK1	ENSG00000152256	-0.10362834551460548	[572]	[479,842,640,561]	-1	hSpCas9	negative selection	5804506
172558803	172558826	2	-	27260156	A375	viability	GGTGTCCTGAGAAGATTATCTGG	PDK1	ENSG00000152256	0.02702986324378659	[408]	[412,756,462,363]	0	hSpCas9	negative selection	5804507
172565010	172565033	2	+	27260156	A375	viability	CCATCTCATCGAAAACACATTGG	PDK1	ENSG00000152256	0.34865160101120307	[950]	[1513,1368,1482,1294]	5	hSpCas9	negative selection	5804508
172565043	172565066	2	-	27260156	A375	viability	ACTTCAAGTACATTGCAGTTTGG	PDK1	ENSG00000152256	0.14326263170174347	[250]	[376,326,306,287]	2	hSpCas9	negative selection	5868758
172566853	172566876	2	+	27260156	A375	viability	TAGATGGCTATGAAAATGCTAGG	PDK1	ENSG00000152256	-0.25347547015181016	[417]	[324,332,378,568]	-4	hSpCas9	negative selection	5868759
172566907	172566930	2	-	27260156	A375	viability	TAGTTCTTCAAGTTCTAGTTCGG	PDK1	ENSG00000152256	0.3646451634009341	[780]	[1050,1346,1101,1211]	5	hSpCas9	negative selection	5868760
172558828	172558851	2	+	27260156	COLO741	viability	CCGTTCAATTGGTACAAAGCTGG	PDK1	ENSG00000152256	-0.2925900527682516	[572]	[694,619,492]	-6	hSpCas9	negative selection	5925757
172558803	172558826	2	-	27260156	COLO741	viability	GGTGTCCTGAGAAGATTATCTGG	PDK1	ENSG00000152256	-0.05532063069256338	[408]	[554,412,540]	-1	hSpCas9	negative selection	5925758
172565010	172565033	2	+	27260156	COLO741	viability	CCATCTCATCGAAAACACATTGG	PDK1	ENSG00000152256	0.23639004372757744	[950]	[1475,1473,1350]	5	hSpCas9	negative selection	5925759
172565043	172565066	2	-	27260156	COLO741	viability	ACTTCAAGTACATTGCAGTTTGG	PDK1	ENSG00000152256	0.3316039288326169	[250]	[467,424,327]	7	hSpCas9	negative selection	5990009
172566853	172566876	2	+	27260156	COLO741	viability	TAGATGGCTATGAAAATGCTAGG	PDK1	ENSG00000152256	-0.42859236605294915	[417]	[468,405,325]	-7	hSpCas9	negative selection	5990010
172566907	172566930	2	-	27260156	COLO741	viability	TAGTTCTTCAAGTTCTAGTTCGG	PDK1	ENSG00000152256	0.09484828613637863	[780]	[1098,1109,993]	2	hSpCas9	negative selection	5990011
172558828	172558851	2	+	27260156	CAL120	viability	CCGTTCAATTGGTACAAAGCTGG	PDK1	ENSG00000152256	-0.35885066870343096	[572]	[811,431,463]	-5	hSpCas9	negative selection	6047008
172558803	172558826	2	-	27260156	CAL120	viability	GGTGTCCTGAGAAGATTATCTGG	PDK1	ENSG00000152256	0.04498352564321664	[408]	[877,386,365]	0	hSpCas9	negative selection	6047009
172565010	172565033	2	+	27260156	CAL120	viability	CCATCTCATCGAAAACACATTGG	PDK1	ENSG00000152256	0.06607201765068726	[950]	[1339,1190,1200]	1	hSpCas9	negative selection	6047010
172565043	172565066	2	-	27260156	CAL120	viability	ACTTCAAGTACATTGCAGTTTGG	PDK1	ENSG00000152256	-0.42077881533078076	[250]	[225,195,275]	-6	hSpCas9	negative selection	6111260
172566853	172566876	2	+	27260156	CAL120	viability	TAGATGGCTATGAAAATGCTAGG	PDK1	ENSG00000152256	-0.12787475982825147	[417]	[676,464,318]	-2	hSpCas9	negative selection	6111261
172566907	172566930	2	-	27260156	CAL120	viability	TAGTTCTTCAAGTTCTAGTTCGG	PDK1	ENSG00000152256	0.13041523857280035	[780]	[1124,999,1074]	2	hSpCas9	negative selection	6111262
172558828	172558851	2	+	27260156	CADOES1	viability	CCGTTCAATTGGTACAAAGCTGG	PDK1	ENSG00000152256	-0.4378411686474472	[572]	[377,300,386,511]	-6	hSpCas9	negative selection	6168259
172558803	172558826	2	-	27260156	CADOES1	viability	GGTGTCCTGAGAAGATTATCTGG	PDK1	ENSG00000152256	-0.20146078772171933	[408]	[337,381,230,373]	-3	hSpCas9	negative selection	6168260
172565010	172565033	2	+	27260156	CADOES1	viability	CCATCTCATCGAAAACACATTGG	PDK1	ENSG00000152256	0.18194308809990356	[950]	[806,869,1068,1277]	3	hSpCas9	negative selection	6168261
172565043	172565066	2	-	27260156	CADOES1	viability	ACTTCAAGTACATTGCAGTTTGG	PDK1	ENSG00000152256	-0.022803655412895862	[250]	[222,159,254,282]	0	hSpCas9	negative selection	6232511
172566853	172566876	2	+	27260156	CADOES1	viability	TAGATGGCTATGAAAATGCTAGG	PDK1	ENSG00000152256	-0.1554860851754642	[417]	[300,221,370,507]	-3	hSpCas9	negative selection	6232512
172566907	172566930	2	-	27260156	CADOES1	viability	TAGTTCTTCAAGTTCTAGTTCGG	PDK1	ENSG00000152256	0.22463547557012864	[780]	[937,739,703,1018]	4	hSpCas9	negative selection	6232513
172558828	172558851	2	+	27260156	EWS502	viability	CCGTTCAATTGGTACAAAGCTGG	PDK1	ENSG00000152256	-0.5274463692474383	[572]	[298,477,516,400]	-7	hSpCas9	negative selection	6289510
172558803	172558826	2	-	27260156	EWS502	viability	GGTGTCCTGAGAAGATTATCTGG	PDK1	ENSG00000152256	-0.12152231823501652	[408]	[374,352,469,398]	-2	hSpCas9	negative selection	6289511
172565010	172565033	2	+	27260156	EWS502	viability	CCATCTCATCGAAAACACATTGG	PDK1	ENSG00000152256	0.20276874060822947	[950]	[1012,1294,1339,986]	3	hSpCas9	negative selection	6289512
172565043	172565066	2	-	27260156	EWS502	viability	ACTTCAAGTACATTGCAGTTTGG	PDK1	ENSG00000152256	0.3880786559662539	[250]	[372,347,314,350]	6	hSpCas9	negative selection	6353762
172566853	172566876	2	+	27260156	EWS502	viability	TAGATGGCTATGAAAATGCTAGG	PDK1	ENSG00000152256	-0.5946854561164334	[417]	[348,322,248,237]	-7	hSpCas9	negative selection	6353763
172566907	172566930	2	-	27260156	EWS502	viability	TAGTTCTTCAAGTTCTAGTTCGG	PDK1	ENSG00000152256	0.19305679086969985	[780]	[746,846,960,1275]	3	hSpCas9	negative selection	6353764
172558828	172558851	2	+	27260156	EW8	viability	CCGTTCAATTGGTACAAAGCTGG	PDK1	ENSG00000152256	-0.3711400148472219	[572]	[262,411,332,420]	-6	hSpCas9	negative selection	6410761
172558803	172558826	2	-	27260156	EW8	viability	GGTGTCCTGAGAAGATTATCTGG	PDK1	ENSG00000152256	0.020448950414525352	[408]	[351,387,329,276]	0	hSpCas9	negative selection	6410762
172565010	172565033	2	+	27260156	EW8	viability	CCATCTCATCGAAAACACATTGG	PDK1	ENSG00000152256	0.5216899302205273	[950]	[1246,1082,759,1405]	8	hSpCas9	negative selection	6410763
172565043	172565066	2	-	27260156	EW8	viability	ACTTCAAGTACATTGCAGTTTGG	PDK1	ENSG00000152256	0.2311720464282937	[250]	[356,237,170,212]	4	hSpCas9	negative selection	6475013
172566853	172566876	2	+	27260156	EW8	viability	TAGATGGCTATGAAAATGCTAGG	PDK1	ENSG00000152256	-0.3783800325435004	[417]	[326,249,206,273]	-6	hSpCas9	negative selection	6475014
172566907	172566930	2	-	27260156	EW8	viability	TAGTTCTTCAAGTTCTAGTTCGG	PDK1	ENSG00000152256	0.27517093635123013	[780]	[847,1054,609,585]	5	hSpCas9	negative selection	6475015
172558828	172558851	2	+	27260156	CORL105	viability	CCGTTCAATTGGTACAAAGCTGG	PDK1	ENSG00000152256	0.1854339010605473	[572]	[598,563,1351,626]	3	hSpCas9	negative selection	6532012
172558803	172558826	2	-	27260156	CORL105	viability	GGTGTCCTGAGAAGATTATCTGG	PDK1	ENSG00000152256	-0.12370283308401048	[408]	[540,297,621,331]	-2	hSpCas9	negative selection	6532013
172565010	172565033	2	+	27260156	CORL105	viability	CCATCTCATCGAAAACACATTGG	PDK1	ENSG00000152256	0.36521424220276955	[950]	[1503,1254,1520,1474]	6	hSpCas9	negative selection	6532014
172565043	172565066	2	-	27260156	CORL105	viability	ACTTCAAGTACATTGCAGTTTGG	PDK1	ENSG00000152256	0.3991384971300145	[250]	[328,515,314,373]	7	hSpCas9	negative selection	6596264
172566853	172566876	2	+	27260156	CORL105	viability	TAGATGGCTATGAAAATGCTAGG	PDK1	ENSG00000152256	-0.4345913692846648	[417]	[323,324,422,384]	-7	hSpCas9	negative selection	6596265
172566907	172566930	2	-	27260156	CORL105	viability	TAGTTCTTCAAGTTCTAGTTCGG	PDK1	ENSG00000152256	0.26788886465631456	[780]	[1067,1002,1198,1148]	5	hSpCas9	negative selection	6596266
172558828	172558851	2	+	27260156	HS294T	viability	CCGTTCAATTGGTACAAAGCTGG	PDK1	ENSG00000152256	0.17566091656905625	[572]	[394,151,178,265]	2	hSpCas9	negative selection	6653263
172558803	172558826	2	-	27260156	HS294T	viability	GGTGTCCTGAGAAGATTATCTGG	PDK1	ENSG00000152256	0.32679383503899634	[408]	[257,115,195,223]	4	hSpCas9	negative selection	6653264
172565010	172565033	2	+	27260156	HS294T	viability	CCATCTCATCGAAAACACATTGG	PDK1	ENSG00000152256	0.6969326040877697	[950]	[758,451,545,617]	8	hSpCas9	negative selection	6653265
172565043	172565066	2	-	27260156	HS294T	viability	ACTTCAAGTACATTGCAGTTTGG	PDK1	ENSG00000152256	0.23856635313092	[250]	[95,75,192,91]	3	hSpCas9	negative selection	6717515
172566853	172566876	2	+	27260156	HS294T	viability	TAGATGGCTATGAAAATGCTAGG	PDK1	ENSG00000152256	-0.15666068750582224	[417]	[200,120,106,145]	-2	hSpCas9	negative selection	6717516
172566907	172566930	2	-	27260156	HS294T	viability	TAGTTCTTCAAGTTCTAGTTCGG	PDK1	ENSG00000152256	0.0689722300872545	[780]	[313,358,273,317]	0	hSpCas9	negative selection	6717517
172558828	172558851	2	+	27260156	HCC44	viability	CCGTTCAATTGGTACAAAGCTGG	PDK1	ENSG00000152256	-0.33870801980740955	[572]	[571,294,823,446]	-5	hSpCas9	negative selection	6774514
172558803	172558826	2	-	27260156	HCC44	viability	GGTGTCCTGAGAAGATTATCTGG	PDK1	ENSG00000152256	-0.026526938235037212	[408]	[337,264,905,399]	0	hSpCas9	negative selection	6774515
172565010	172565033	2	+	27260156	HCC44	viability	CCATCTCATCGAAAACACATTGG	PDK1	ENSG00000152256	0.38834590585832185	[950]	[1644,1181,1936,1013]	6	hSpCas9	negative selection	6774516
172565043	172565066	2	-	27260156	HCC44	viability	ACTTCAAGTACATTGCAGTTTGG	PDK1	ENSG00000152256	0.057856494575530104	[250]	[240,250,346,348]	0	hSpCas9	negative selection	6838766
172566853	172566876	2	+	27260156	HCC44	viability	TAGATGGCTATGAAAATGCTAGG	PDK1	ENSG00000152256	-0.21307139257614716	[417]	[457,325,498,377]	-3	hSpCas9	negative selection	6838767
172566907	172566930	2	-	27260156	HCC44	viability	TAGTTCTTCAAGTTCTAGTTCGG	PDK1	ENSG00000152256	0.44782857057827197	[780]	[994,1364,1453,1002]	7	hSpCas9	negative selection	6838768
172558828	172558851	2	+	27260156	G402	viability	CCGTTCAATTGGTACAAAGCTGG	PDK1	ENSG00000152256	-0.6100575937515618	[572]	[182,556,628,428]	-6	hSpCas9	negative selection	6895765
172558803	172558826	2	-	27260156	G402	viability	GGTGTCCTGAGAAGATTATCTGG	PDK1	ENSG00000152256	-0.5429752948483264	[408]	[248,333,263,499]	-6	hSpCas9	negative selection	6895766
172565010	172565033	2	+	27260156	G402	viability	CCATCTCATCGAAAACACATTGG	PDK1	ENSG00000152256	0.5592657005137658	[950]	[1261,2181,1987,1379]	7	hSpCas9	negative selection	6895767
172565043	172565066	2	-	27260156	G402	viability	ACTTCAAGTACATTGCAGTTTGG	PDK1	ENSG00000152256	0.5224719734357068	[250]	[378,329,533,496]	6	hSpCas9	negative selection	6960017
172566853	172566876	2	+	27260156	G402	viability	TAGATGGCTATGAAAATGCTAGG	PDK1	ENSG00000152256	-0.4404329084913693	[417]	[532,216,443,323]	-5	hSpCas9	negative selection	6960018
172566907	172566930	2	-	27260156	G402	viability	TAGTTCTTCAAGTTCTAGTTCGG	PDK1	ENSG00000152256	0.44290663486877346	[780]	[1441,1203,1070,1466]	5	hSpCas9	negative selection	6960019
172558828	172558851	2	+	27260156	L33	viability	CCGTTCAATTGGTACAAAGCTGG	PDK1	ENSG00000152256	-0.02403961102798058	[572]	[507,256,383,509]	0	hSpCas9	negative selection	7017016
172558803	172558826	2	-	27260156	L33	viability	GGTGTCCTGAGAAGATTATCTGG	PDK1	ENSG00000152256	0.14369037024691272	[408]	[384,181,315,476]	3	hSpCas9	negative selection	7017017
172565010	172565033	2	+	27260156	L33	viability	CCATCTCATCGAAAACACATTGG	PDK1	ENSG00000152256	0.45135018965454554	[950]	[1337,493,906,1214]	8	hSpCas9	negative selection	7017018
172565043	172565066	2	-	27260156	L33	viability	ACTTCAAGTACATTGCAGTTTGG	PDK1	ENSG00000152256	0.24435164052246305	[250]	[325,138,171,249]	5	hSpCas9	negative selection	7081268
172566853	172566876	2	+	27260156	L33	viability	TAGATGGCTATGAAAATGCTAGG	PDK1	ENSG00000152256	-0.17806606186061497	[417]	[260,141,283,420]	-4	hSpCas9	negative selection	7081269
172566907	172566930	2	-	27260156	L33	viability	TAGTTCTTCAAGTTCTAGTTCGG	PDK1	ENSG00000152256	0.07627030111136157	[780]	[724,348,486,942]	1	hSpCas9	negative selection	7081270
172558828	172558851	2	+	27260156	K562	viability	CCGTTCAATTGGTACAAAGCTGG	PDK1	ENSG00000152256	-0.15618916037771804	[572]	[560,435,463,378]	-2	hSpCas9	negative selection	7138267
172558803	172558826	2	-	27260156	K562	viability	GGTGTCCTGAGAAGATTATCTGG	PDK1	ENSG00000152256	0.7428296388984608	[408]	[612,375,985,457]	8	hSpCas9	negative selection	7138268
172565010	172565033	2	+	27260156	K562	viability	CCATCTCATCGAAAACACATTGG	PDK1	ENSG00000152256	0.4081176377478899	[950]	[1306,860,1259,1055]	5	hSpCas9	negative selection	7138269
172565043	172565066	2	-	27260156	K562	viability	ACTTCAAGTACATTGCAGTTTGG	PDK1	ENSG00000152256	0.4990560481712764	[250]	[259,258,336,385]	6	hSpCas9	negative selection	7202519
172566853	172566876	2	+	27260156	K562	viability	TAGATGGCTATGAAAATGCTAGG	PDK1	ENSG00000152256	-0.757287881866723	[417]	[153,409,111,206]	-7	hSpCas9	negative selection	7202520
172566907	172566930	2	-	27260156	K562	viability	TAGTTCTTCAAGTTCTAGTTCGG	PDK1	ENSG00000152256	0.24483802414626554	[780]	[862,850,962,631]	3	hSpCas9	negative selection	7202521
172558828	172558851	2	+	27260156	HT29	viability	CCGTTCAATTGGTACAAAGCTGG	PDK1	ENSG00000152256	-0.4288187979203175	[572]	[480,615,576,410]	-7	hSpCas9	negative selection	7259518
172558803	172558826	2	-	27260156	HT29	viability	GGTGTCCTGAGAAGATTATCTGG	PDK1	ENSG00000152256	0.027831133500715005	[408]	[552,469,465,531]	0	hSpCas9	negative selection	7259519
172565010	172565033	2	+	27260156	HT29	viability	CCATCTCATCGAAAACACATTGG	PDK1	ENSG00000152256	0.16294229769230428	[950]	[1631,1378,1192,1029]	3	hSpCas9	negative selection	7259520
172565043	172565066	2	-	27260156	HT29	viability	ACTTCAAGTACATTGCAGTTTGG	PDK1	ENSG00000152256	0.3185411260573935	[250]	[348,438,309,418]	6	hSpCas9	negative selection	7323770
172566853	172566876	2	+	27260156	HT29	viability	TAGATGGCTATGAAAATGCTAGG	PDK1	ENSG00000152256	-0.18593262972571106	[417]	[445,415,482,436]	-4	hSpCas9	negative selection	7323771
172566907	172566930	2	-	27260156	HT29	viability	TAGTTCTTCAAGTTCTAGTTCGG	PDK1	ENSG00000152256	0.3559782306220799	[780]	[1219,1317,1298,1044]	7	hSpCas9	negative selection	7323772
172558828	172558851	2	+	27260156	MHHES1	viability	CCGTTCAATTGGTACAAAGCTGG	PDK1	ENSG00000152256	0.09951066547524118	[572]	[903,891,527,512]	1	hSpCas9	negative selection	7380769
172558803	172558826	2	-	27260156	MHHES1	viability	GGTGTCCTGAGAAGATTATCTGG	PDK1	ENSG00000152256	-0.1591099386774324	[408]	[410,486,425,340]	-3	hSpCas9	negative selection	7380770
172565010	172565033	2	+	27260156	MHHES1	viability	CCATCTCATCGAAAACACATTGG	PDK1	ENSG00000152256	0.3769137765680046	[950]	[1917,1469,1366,951]	6	hSpCas9	negative selection	7380771
172565043	172565066	2	-	27260156	MHHES1	viability	ACTTCAAGTACATTGCAGTTTGG	PDK1	ENSG00000152256	0.44400661148218173	[250]	[396,458,343,346]	7	hSpCas9	negative selection	7445021
172566853	172566876	2	+	27260156	MHHES1	viability	TAGATGGCTATGAAAATGCTAGG	PDK1	ENSG00000152256	-0.5902267708530268	[417]	[537,299,237,215]	-8	hSpCas9	negative selection	7445022
172566907	172566930	2	-	27260156	MHHES1	viability	TAGTTCTTCAAGTTCTAGTTCGG	PDK1	ENSG00000152256	0.12583899043608782	[780]	[1034,1012,1063,765]	2	hSpCas9	negative selection	7445023
172558828	172558851	2	+	27260156	MEWO	viability	CCGTTCAATTGGTACAAAGCTGG	PDK1	ENSG00000152256	0.12155043527225645	[572]	[577,677,491]	2	hSpCas9	negative selection	7502020
172558803	172558826	2	-	27260156	MEWO	viability	GGTGTCCTGAGAAGATTATCTGG	PDK1	ENSG00000152256	0.004142793970977332	[408]	[357,416,370]	0	hSpCas9	negative selection	7502021
172565010	172565033	2	+	27260156	MEWO	viability	CCATCTCATCGAAAACACATTGG	PDK1	ENSG00000152256	0.15970046085030232	[950]	[1131,816,1059]	3	hSpCas9	negative selection	7502022
172565043	172565066	2	-	27260156	MEWO	viability	ACTTCAAGTACATTGCAGTTTGG	PDK1	ENSG00000152256	0.2685896251751113	[250]	[356,268,236]	6	hSpCas9	negative selection	7566272
172566853	172566876	2	+	27260156	MEWO	viability	TAGATGGCTATGAAAATGCTAGG	PDK1	ENSG00000152256	0.04637280332833678	[417]	[406,411,392]	1	hSpCas9	negative selection	7566273
172566907	172566930	2	-	27260156	MEWO	viability	TAGTTCTTCAAGTTCTAGTTCGG	PDK1	ENSG00000152256	0.1971405363177906	[780]	[960,774,800]	4	hSpCas9	negative selection	7566274
172558828	172558851	2	+	27260156	LNCAPCLONEFGC	viability	CCGTTCAATTGGTACAAAGCTGG	PDK1	ENSG00000152256	-0.056538872559108194	[572]	[438,439,652,491]	-1	hSpCas9	negative selection	7623271
172558803	172558826	2	-	27260156	LNCAPCLONEFGC	viability	GGTGTCCTGAGAAGATTATCTGG	PDK1	ENSG00000152256	-0.0727431402377709	[408]	[320,327,499,283]	-1	hSpCas9	negative selection	7623272
172565010	172565033	2	+	27260156	LNCAPCLONEFGC	viability	CCATCTCATCGAAAACACATTGG	PDK1	ENSG00000152256	0.29979638685749554	[950]	[997,918,1244,1116]	5	hSpCas9	negative selection	7623273
172565043	172565066	2	-	27260156	LNCAPCLONEFGC	viability	ACTTCAAGTACATTGCAGTTTGG	PDK1	ENSG00000152256	0.4587852035846502	[250]	[229,383,287,340]	7	hSpCas9	negative selection	7687523
172566853	172566876	2	+	27260156	LNCAPCLONEFGC	viability	TAGATGGCTATGAAAATGCTAGG	PDK1	ENSG00000152256	-0.18699288343720627	[417]	[263,285,435,363]	-3	hSpCas9	negative selection	7687524
172566907	172566930	2	-	27260156	LNCAPCLONEFGC	viability	TAGTTCTTCAAGTTCTAGTTCGG	PDK1	ENSG00000152256	0.3475467407366689	[780]	[797,736,1257,872]	5	hSpCas9	negative selection	7687525
172558828	172558851	2	+	27260156	PANC0327	viability	CCGTTCAATTGGTACAAAGCTGG	PDK1	ENSG00000152256	-0.49458524283134914	[572]	[327,441,417,243]	-6	hSpCas9	negative selection	7744522
172558803	172558826	2	-	27260156	PANC0327	viability	GGTGTCCTGAGAAGATTATCTGG	PDK1	ENSG00000152256	-0.018965993436260098	[408]	[347,280,245,567]	0	hSpCas9	negative selection	7744523
172565010	172565033	2	+	27260156	PANC0327	viability	CCATCTCATCGAAAACACATTGG	PDK1	ENSG00000152256	0.4479552222656924	[950]	[1241,857,1440,1113]	6	hSpCas9	negative selection	7744524
172565043	172565066	2	-	27260156	PANC0327	viability	ACTTCAAGTACATTGCAGTTTGG	PDK1	ENSG00000152256	-0.006724386334446275	[250]	[136,180,270,296]	0	hSpCas9	negative selection	7808774
172566853	172566876	2	+	27260156	PANC0327	viability	TAGATGGCTATGAAAATGCTAGG	PDK1	ENSG00000152256	-0.016377084335135073	[417]	[545,234,320,397]	0	hSpCas9	negative selection	7808775
172566907	172566930	2	-	27260156	PANC0327	viability	TAGTTCTTCAAGTTCTAGTTCGG	PDK1	ENSG00000152256	0.23412364138896602	[780]	[738,707,1122,701]	3	hSpCas9	negative selection	7808776
172558828	172558851	2	+	27260156	NCIH2009	viability	CCGTTCAATTGGTACAAAGCTGG	PDK1	ENSG00000152256	-0.07078623803235998	[572]	[1098,485,771]	-1	hSpCas9	negative selection	7865773
172558803	172558826	2	-	27260156	NCIH2009	viability	GGTGTCCTGAGAAGATTATCTGG	PDK1	ENSG00000152256	0.2286037223529505	[408]	[528,489,963]	3	hSpCas9	negative selection	7865774
172565010	172565033	2	+	27260156	NCIH2009	viability	CCATCTCATCGAAAACACATTGG	PDK1	ENSG00000152256	0.5936385907008623	[950]	[2204,1856,1991]	7	hSpCas9	negative selection	7865775
172565043	172565066	2	-	27260156	NCIH2009	viability	ACTTCAAGTACATTGCAGTTTGG	PDK1	ENSG00000152256	0.3552360362991851	[250]	[490,415,446]	5	hSpCas9	negative selection	7930025
172566853	172566876	2	+	27260156	NCIH2009	viability	TAGATGGCTATGAAAATGCTAGG	PDK1	ENSG00000152256	-0.32327780212499385	[417]	[551,376,488]	-4	hSpCas9	negative selection	7930026
172566907	172566930	2	-	27260156	NCIH2009	viability	TAGTTCTTCAAGTTCTAGTTCGG	PDK1	ENSG00000152256	-0.013749419886189385	[780]	[1384,792,1127]	0	hSpCas9	negative selection	7930027
172558828	172558851	2	+	27260156	NCIH1373	viability	CCGTTCAATTGGTACAAAGCTGG	PDK1	ENSG00000152256	-0.03293780674368185	[572]	[864,743,343,152]	0	hSpCas9	negative selection	7987024
172558803	172558826	2	-	27260156	NCIH1373	viability	GGTGTCCTGAGAAGATTATCTGG	PDK1	ENSG00000152256	0.5590912789185547	[408]	[803,886,543,117]	5	hSpCas9	negative selection	7987025
172565010	172565033	2	+	27260156	NCIH1373	viability	CCATCTCATCGAAAACACATTGG	PDK1	ENSG00000152256	0.3761067018093964	[950]	[2069,890,1229,395]	3	hSpCas9	negative selection	7987026
172565043	172565066	2	-	27260156	NCIH1373	viability	ACTTCAAGTACATTGCAGTTTGG	PDK1	ENSG00000152256	0.5340613829369397	[250]	[321,201,453,176]	5	hSpCas9	negative selection	8051276
172566853	172566876	2	+	27260156	NCIH1373	viability	TAGATGGCTATGAAAATGCTAGG	PDK1	ENSG00000152256	-0.8850383831094015	[417]	[247,178,196,106]	-7	hSpCas9	negative selection	8051277
172566907	172566930	2	-	27260156	NCIH1373	viability	TAGTTCTTCAAGTTCTAGTTCGG	PDK1	ENSG00000152256	0.29130139209305195	[780]	[815,1157,1379,224]	3	hSpCas9	negative selection	8051278
172558828	172558851	2	+	27260156	PATU8902	viability	CCGTTCAATTGGTACAAAGCTGG	PDK1	ENSG00000152256	-0.17473640711563224	[572]	[627,755,722,712]	-2	hSpCas9	negative selection	8108275
172558803	172558826	2	-	27260156	PATU8902	viability	GGTGTCCTGAGAAGATTATCTGG	PDK1	ENSG00000152256	0.5744401869809083	[408]	[1160,1059,492,748]	6	hSpCas9	negative selection	8108276
172565010	172565033	2	+	27260156	PATU8902	viability	CCATCTCATCGAAAACACATTGG	PDK1	ENSG00000152256	0.43266954670414126	[950]	[2308,1499,1264,2244]	4	hSpCas9	negative selection	8108277
172565043	172565066	2	-	27260156	PATU8902	viability	ACTTCAAGTACATTGCAGTTTGG	PDK1	ENSG00000152256	0.45171809192410556	[250]	[710,227,572,352]	5	hSpCas9	negative selection	8172527
172566853	172566876	2	+	27260156	PATU8902	viability	TAGATGGCTATGAAAATGCTAGG	PDK1	ENSG00000152256	-0.5336911364243917	[417]	[755,320,172,410]	-5	hSpCas9	negative selection	8172528
172566907	172566930	2	-	27260156	PATU8902	viability	TAGTTCTTCAAGTTCTAGTTCGG	PDK1	ENSG00000152256	0.5062465926389884	[780]	[1433,1094,1664,1995]	5	hSpCas9	negative selection	8172529
172558828	172558851	2	+	27260156	PANC1	viability	CCGTTCAATTGGTACAAAGCTGG	PDK1	ENSG00000152256	-0.46553469809413484	[572]	[477,517,273,204]	-6	hSpCas9	negative selection	8229526
172558803	172558826	2	-	27260156	PANC1	viability	GGTGTCCTGAGAAGATTATCTGG	PDK1	ENSG00000152256	0.14134148723617038	[408]	[369,520,355,332]	2	hSpCas9	negative selection	8229527
172565010	172565033	2	+	27260156	PANC1	viability	CCATCTCATCGAAAACACATTGG	PDK1	ENSG00000152256	0.25933548021639563	[950]	[979,1397,842,789]	4	hSpCas9	negative selection	8229528
172565043	172565066	2	-	27260156	PANC1	viability	ACTTCAAGTACATTGCAGTTTGG	PDK1	ENSG00000152256	0.5711702244445429	[250]	[195,571,309,261]	8	hSpCas9	negative selection	8293778
172566853	172566876	2	+	27260156	PANC1	viability	TAGATGGCTATGAAAATGCTAGG	PDK1	ENSG00000152256	-0.295969803673423	[417]	[217,541,225,239]	-5	hSpCas9	negative selection	8293779
172566907	172566930	2	-	27260156	PANC1	viability	TAGTTCTTCAAGTTCTAGTTCGG	PDK1	ENSG00000152256	0.2711664229907519	[780]	[791,843,827,773]	4	hSpCas9	negative selection	8293780
172558828	172558851	2	+	27260156	PANC0813	viability	CCGTTCAATTGGTACAAAGCTGG	PDK1	ENSG00000152256	0.27735328990806973	[572]	[906,812,842,712]	4	hSpCas9	negative selection	8350777
172558803	172558826	2	-	27260156	PANC0813	viability	GGTGTCCTGAGAAGATTATCTGG	PDK1	ENSG00000152256	0.22334535947542056	[408]	[499,528,709,501]	3	hSpCas9	negative selection	8350778
172565010	172565033	2	+	27260156	PANC0813	viability	CCATCTCATCGAAAACACATTGG	PDK1	ENSG00000152256	0.5100300678928666	[950]	[1652,1675,1503,1535]	7	hSpCas9	negative selection	8350779
172565043	172565066	2	-	27260156	PANC0813	viability	ACTTCAAGTACATTGCAGTTTGG	PDK1	ENSG00000152256	0.172287153532375	[250]	[451,267,350,271]	3	hSpCas9	negative selection	8415029
172566853	172566876	2	+	27260156	PANC0813	viability	TAGATGGCTATGAAAATGCTAGG	PDK1	ENSG00000152256	-0.1618285827249829	[417]	[415,447,418,467]	-3	hSpCas9	negative selection	8415030
172566907	172566930	2	-	27260156	PANC0813	viability	TAGTTCTTCAAGTTCTAGTTCGG	PDK1	ENSG00000152256	0.19164057202601636	[780]	[1339,877,1107,898]	3	hSpCas9	negative selection	8415031
172558828	172558851	2	+	27260156	RDES	viability	CCGTTCAATTGGTACAAAGCTGG	PDK1	ENSG00000152256	-0.2430476177870859	[572]	[419,422,798,632]	-4	hSpCas9	negative selection	8472028
172558803	172558826	2	-	27260156	RDES	viability	GGTGTCCTGAGAAGATTATCTGG	PDK1	ENSG00000152256	0.027497242105142816	[408]	[345,492,511,599]	0	hSpCas9	negative selection	8472029
172565010	172565033	2	+	27260156	RDES	viability	CCATCTCATCGAAAACACATTGG	PDK1	ENSG00000152256	0.23210433671767738	[950]	[1134,1304,1387,1305]	4	hSpCas9	negative selection	8472030
172565043	172565066	2	-	27260156	RDES	viability	ACTTCAAGTACATTGCAGTTTGG	PDK1	ENSG00000152256	0.39214423453922087	[250]	[276,375,426,460]	6	hSpCas9	negative selection	8536280
172566853	172566876	2	+	27260156	RDES	viability	TAGATGGCTATGAAAATGCTAGG	PDK1	ENSG00000152256	-0.44032292766605563	[417]	[294,306,384,452]	-6	hSpCas9	negative selection	8536281
172566907	172566930	2	-	27260156	RDES	viability	TAGTTCTTCAAGTTCTAGTTCGG	PDK1	ENSG00000152256	0.1457399253104793	[780]	[819,836,1054,1340]	2	hSpCas9	negative selection	8536282
172558828	172558851	2	+	27260156	PC3	viability	CCGTTCAATTGGTACAAAGCTGG	PDK1	ENSG00000152256	-0.2338348957603665	[572]	[231,532,681,649]	-5	hSpCas9	negative selection	8593279
172558803	172558826	2	-	27260156	PC3	viability	GGTGTCCTGAGAAGATTATCTGG	PDK1	ENSG00000152256	-0.14291547224131063	[408]	[276,472,493,267]	-3	hSpCas9	negative selection	8593280
172565010	172565033	2	+	27260156	PC3	viability	CCATCTCATCGAAAACACATTGG	PDK1	ENSG00000152256	0.102675643445723	[950]	[604,1008,1630,1157]	2	hSpCas9	negative selection	8593281
172565043	172565066	2	-	27260156	PC3	viability	ACTTCAAGTACATTGCAGTTTGG	PDK1	ENSG00000152256	0.41654529640258114	[250]	[271,287,428,373]	8	hSpCas9	negative selection	8657531
172566853	172566876	2	+	27260156	PC3	viability	TAGATGGCTATGAAAATGCTAGG	PDK1	ENSG00000152256	-0.345890115303792	[417]	[193,379,284,465]	-7	hSpCas9	negative selection	8657532
172566907	172566930	2	-	27260156	PC3	viability	TAGTTCTTCAAGTTCTAGTTCGG	PDK1	ENSG00000152256	0.06535026689800738	[780]	[489,694,1462,941]	1	hSpCas9	negative selection	8657533
172558828	172558851	2	+	27260156	PATU8988T	viability	CCGTTCAATTGGTACAAAGCTGG	PDK1	ENSG00000152256	0.08010733712690954	[572]	[527,515,634,660]	1	hSpCas9	negative selection	8714530
172558803	172558826	2	-	27260156	PATU8988T	viability	GGTGTCCTGAGAAGATTATCTGG	PDK1	ENSG00000152256	0.21062688181500222	[408]	[454,446,440,487]	3	hSpCas9	negative selection	8714531
172565010	172565033	2	+	27260156	PATU8988T	viability	CCATCTCATCGAAAACACATTGG	PDK1	ENSG00000152256	0.3185845947360504	[950]	[1041,1400,1005,1161]	5	hSpCas9	negative selection	8714532
172565043	172565066	2	-	27260156	PATU8988T	viability	ACTTCAAGTACATTGCAGTTTGG	PDK1	ENSG00000152256	0.3267763299914531	[250]	[275,336,339,262]	5	hSpCas9	negative selection	8778782
172566853	172566876	2	+	27260156	PATU8988T	viability	TAGATGGCTATGAAAATGCTAGG	PDK1	ENSG00000152256	-0.04046977658163006	[417]	[509,470,253,340]	0	hSpCas9	negative selection	8778783
172566907	172566930	2	-	27260156	PATU8988T	viability	TAGTTCTTCAAGTTCTAGTTCGG	PDK1	ENSG00000152256	0.20906317202237057	[780]	[835,844,823,991]	3	hSpCas9	negative selection	8778784
172558828	172558851	2	+	27260156	T47D	viability	CCGTTCAATTGGTACAAAGCTGG	PDK1	ENSG00000152256	-0.3437567437922795	[572]	[527,401,587,597]	-6	hSpCas9	negative selection	8835781
172558803	172558826	2	-	27260156	T47D	viability	GGTGTCCTGAGAAGATTATCTGG	PDK1	ENSG00000152256	-0.012622298132327264	[408]	[474,498,467,443]	0	hSpCas9	negative selection	8835782
172565010	172565033	2	+	27260156	T47D	viability	CCATCTCATCGAAAACACATTGG	PDK1	ENSG00000152256	0.28030987092048965	[950]	[1208,1201,1488,1495]	6	hSpCas9	negative selection	8835783
172565043	172565066	2	-	27260156	T47D	viability	ACTTCAAGTACATTGCAGTTTGG	PDK1	ENSG00000152256	0.2818164593850132	[250]	[333,423,355,299]	6	hSpCas9	negative selection	8900033
172566853	172566876	2	+	27260156	T47D	viability	TAGATGGCTATGAAAATGCTAGG	PDK1	ENSG00000152256	-0.06370908704136272	[417]	[414,479,511,453]	-1	hSpCas9	negative selection	8900034
172566907	172566930	2	-	27260156	T47D	viability	TAGTTCTTCAAGTTCTAGTTCGG	PDK1	ENSG00000152256	0.29733088856269163	[780]	[1099,1085,1207,1077]	6	hSpCas9	negative selection	8900035
172558828	172558851	2	+	27260156	SU8686	viability	CCGTTCAATTGGTACAAAGCTGG	PDK1	ENSG00000152256	-0.03556080150614155	[572]	[538,516,523,654]	0	hSpCas9	negative selection	8957032
172558803	172558826	2	-	27260156	SU8686	viability	GGTGTCCTGAGAAGATTATCTGG	PDK1	ENSG00000152256	0.017991943082482698	[408]	[413,463,284,475]	0	hSpCas9	negative selection	8957033
172565010	172565033	2	+	27260156	SU8686	viability	CCATCTCATCGAAAACACATTGG	PDK1	ENSG00000152256	0.5577739577308658	[950]	[1389,1117,1373,1752]	8	hSpCas9	negative selection	8957034
172565043	172565066	2	-	27260156	SU8686	viability	ACTTCAAGTACATTGCAGTTTGG	PDK1	ENSG00000152256	0.18355972431902978	[250]	[275,244,190,445]	3	hSpCas9	negative selection	9021284
172566853	172566876	2	+	27260156	SU8686	viability	TAGATGGCTATGAAAATGCTAGG	PDK1	ENSG00000152256	-0.29767065643192947	[417]	[375,270,236,487]	-5	hSpCas9	negative selection	9021285
172566907	172566930	2	-	27260156	SU8686	viability	TAGTTCTTCAAGTTCTAGTTCGG	PDK1	ENSG00000152256	-0.013670187955092783	[780]	[616,686,777,1054]	0	hSpCas9	negative selection	9021286
172558828	172558851	2	+	27260156	SKES1	viability	CCGTTCAATTGGTACAAAGCTGG	PDK1	ENSG00000152256	-0.28358953315114044	[572]	[594,454,481,368]	-6	hSpCas9	negative selection	9078283
172558803	172558826	2	-	27260156	SKES1	viability	GGTGTCCTGAGAAGATTATCTGG	PDK1	ENSG00000152256	0.09151771189572588	[408]	[654,396,406,315]	2	hSpCas9	negative selection	9078284
172565010	172565033	2	+	27260156	SKES1	viability	CCATCTCATCGAAAACACATTGG	PDK1	ENSG00000152256	0.24387134938725596	[950]	[1177,1194,1103,1031]	5	hSpCas9	negative selection	9078285
172565043	172565066	2	-	27260156	SKES1	viability	ACTTCAAGTACATTGCAGTTTGG	PDK1	ENSG00000152256	0.1899190389005444	[250]	[295,324,299,230]	4	hSpCas9	negative selection	9142535
172566853	172566876	2	+	27260156	SKES1	viability	TAGATGGCTATGAAAATGCTAGG	PDK1	ENSG00000152256	-0.44218830408173626	[417]	[486,238,256,263]	-7	hSpCas9	negative selection	9142536
172566907	172566930	2	-	27260156	SKES1	viability	TAGTTCTTCAAGTTCTAGTTCGG	PDK1	ENSG00000152256	0.2362067082494076	[780]	[1058,916,807,899]	5	hSpCas9	negative selection	9142537
172558828	172558851	2	+	27260156	TOV112D	viability	CCGTTCAATTGGTACAAAGCTGG	PDK1	ENSG00000152256	-0.4780373483892155	[572]	[558,348,313,421]	-7	hSpCas9	negative selection	9199534
172558803	172558826	2	-	27260156	TOV112D	viability	GGTGTCCTGAGAAGATTATCTGG	PDK1	ENSG00000152256	0.0019445747671557878	[408]	[434,486,362,376]	0	hSpCas9	negative selection	9199535
172565010	172565033	2	+	27260156	TOV112D	viability	CCATCTCATCGAAAACACATTGG	PDK1	ENSG00000152256	0.26625867092724254	[950]	[948,1421,1089,1169]	5	hSpCas9	negative selection	9199536
172565043	172565066	2	-	27260156	TOV112D	viability	ACTTCAAGTACATTGCAGTTTGG	PDK1	ENSG00000152256	0.3739283045764127	[250]	[243,471,302,312]	7	hSpCas9	negative selection	9263786
172566853	172566876	2	+	27260156	TOV112D	viability	TAGATGGCTATGAAAATGCTAGG	PDK1	ENSG00000152256	0.3418958018677573	[417]	[504,584,556,486]	6	hSpCas9	negative selection	9263787
172566907	172566930	2	-	27260156	TOV112D	viability	TAGTTCTTCAAGTTCTAGTTCGG	PDK1	ENSG00000152256	0.3472846949865803	[780]	[838,1181,864,1121]	6	hSpCas9	negative selection	9263788
172558828	172558851	2	+	27260156	TC71	viability	CCGTTCAATTGGTACAAAGCTGG	PDK1	ENSG00000152256	-0.34272132650916637	[572]	[358,553,503,524]	-7	hSpCas9	negative selection	9320785
172558803	172558826	2	-	27260156	TC71	viability	GGTGTCCTGAGAAGATTATCTGG	PDK1	ENSG00000152256	0.2960102710729352	[408]	[541,451,521,643]	7	hSpCas9	negative selection	9320786
172565010	172565033	2	+	27260156	TC71	viability	CCATCTCATCGAAAACACATTGG	PDK1	ENSG00000152256	0.11956396164086303	[950]	[1182,1159,1014,1070]	3	hSpCas9	negative selection	9320787
172565043	172565066	2	-	27260156	TC71	viability	ACTTCAAGTACATTGCAGTTTGG	PDK1	ENSG00000152256	0.07610649115049584	[250]	[289,327,253,261]	2	hSpCas9	negative selection	9385037
172566853	172566876	2	+	27260156	TC71	viability	TAGATGGCTATGAAAATGCTAGG	PDK1	ENSG00000152256	-0.434099289634447	[417]	[277,393,343,309]	-8	hSpCas9	negative selection	9385038
172566907	172566930	2	-	27260156	TC71	viability	TAGTTCTTCAAGTTCTAGTTCGG	PDK1	ENSG00000152256	0.31478603442025743	[780]	[938,1106,921,1213]	7	hSpCas9	negative selection	9385039
172558828	172558851	2	+	27260156	TC32	viability	CCGTTCAATTGGTACAAAGCTGG	PDK1	ENSG00000152256	-0.03662400129777152	[572]	[378,522,660,547]	0	hSpCas9	negative selection	9442036
172558803	172558826	2	-	27260156	TC32	viability	GGTGTCCTGAGAAGATTATCTGG	PDK1	ENSG00000152256	-0.037937811737542654	[408]	[400,287,530,306]	0	hSpCas9	negative selection	9442037
172565010	172565033	2	+	27260156	TC32	viability	CCATCTCATCGAAAACACATTGG	PDK1	ENSG00000152256	0.0847619724287072	[950]	[914,752,1247,946]	1	hSpCas9	negative selection	9442038
172565043	172565066	2	-	27260156	TC32	viability	ACTTCAAGTACATTGCAGTTTGG	PDK1	ENSG00000152256	0.06734996959872153	[250]	[279,191,270,250]	1	hSpCas9	negative selection	9506288
172566853	172566876	2	+	27260156	TC32	viability	TAGATGGCTATGAAAATGCTAGG	PDK1	ENSG00000152256	-0.3844352621778805	[417]	[347,164,358,373]	-6	hSpCas9	negative selection	9506289
172566907	172566930	2	-	27260156	TC32	viability	TAGTTCTTCAAGTTCTAGTTCGG	PDK1	ENSG00000152256	0.29048212557999753	[780]	[955,708,1325,668]	5	hSpCas9	negative selection	9506290
172556282	172556305	2	-	27869803	HPAFII	viability after 27 days	AGCGCGCGTAGAAGTCCACCTGG	PDK1	ENSG00000152256	-0.2717283538477031	[123]	[89,23,NaN]	-2	hSpCas9	negative selection	9572335
172558828	172558851	2	+	27869803	HPAFII	viability after 27 days	CCGTTCAATTGGTACAAAGCTGG	PDK1	ENSG00000152256	0.5441236663926967	[533]	[392,422,NaN]	4	hSpCas9	negative selection	9572336
172564563	172564586	2	-	27869803	HPAFII	viability after 27 days	CCTTGTATTCAATCACACCCTGG	PDK1	ENSG00000152256	0.35001063685540224	[406]	[287,259,NaN]	3	hSpCas9	negative selection	9572337
172568748	172568771	2	+	27869803	HPAFII	viability after 27 days	ACCAGGACAGCCAATACAAGTGG	PDK1	ENSG00000152256	-0.326137484071776	[521]	[129,292,NaN]	-2	hSpCas9	negative selection	9572338
172586372	172586395	2	-	27869803	HPAFII	viability after 27 days	ACATACCAGAGGCACTGCGCGGG	PDK1	ENSG00000152256	-1.235973501740783	[379]	[98,72,NaN]	-7	hSpCas9	negative selection	9572339
172595859	172595882	2	-	27869803	HPAFII	viability after 27 days	CAGGCAGCTTTGTTATACACTGG	PDK1	ENSG00000152256	-0.22204931009835305	[453]	[238,175,NaN]	-2	hSpCas9	negative selection	9572340
172556282	172556305	2	-	27869803	HPAFII	viability after 15 days	AGCGCGCGTAGAAGTCCACCTGG	PDK1	ENSG00000152256	-0.36109251609193915	[123]	[186,51,NaN]	-4	hSpCas9	negative selection	9654784
172558828	172558851	2	+	27869803	HPAFII	viability after 15 days	CCGTTCAATTGGTACAAAGCTGG	PDK1	ENSG00000152256	-0.0009494288878073576	[533]	[694,497,NaN]	0	hSpCas9	negative selection	9654785
172564563	172564586	2	-	27869803	HPAFII	viability after 15 days	CCTTGTATTCAATCACACCCTGG	PDK1	ENSG00000152256	0.16856686846419988	[406]	[794,302,NaN]	2	hSpCas9	negative selection	9654786
172568748	172568771	2	+	27869803	HPAFII	viability after 15 days	ACCAGGACAGCCAATACAAGTGG	PDK1	ENSG00000152256	-0.5392911801281968	[521]	[406,372,NaN]	-5	hSpCas9	negative selection	9654787
172586372	172586395	2	-	27869803	HPAFII	viability after 15 days	ACATACCAGAGGCACTGCGCGGG	PDK1	ENSG00000152256	-1.051027821001324	[379]	[222,180,NaN]	-8	hSpCas9	negative selection	9654788
172595859	172595882	2	-	27869803	HPAFII	viability after 15 days	CAGGCAGCTTTGTTATACACTGG	PDK1	ENSG00000152256	-0.5897447522607248	[453]	[412,268,NaN]	-6	hSpCas9	negative selection	9654789
172556282	172556305	2	-	27869803	ASPC1	viability after 36 days	AGCGCGCGTAGAAGTCCACCTGG	PDK1	ENSG00000152256	0.588748455451822	[414]	[272,315,98]	6	hSpCas9	negative selection	9737233
172558828	172558851	2	+	27869803	ASPC1	viability after 36 days	CCGTTCAATTGGTACAAAGCTGG	PDK1	ENSG00000152256	0.29391087510056435	[1252]	[499,670,448]	3	hSpCas9	negative selection	9737234
172564563	172564586	2	-	27869803	ASPC1	viability after 36 days	CCTTGTATTCAATCACACCCTGG	PDK1	ENSG00000152256	-0.3425165822779894	[738]	[453,57,140]	-4	hSpCas9	negative selection	9737235
172568748	172568771	2	+	27869803	ASPC1	viability after 36 days	ACCAGGACAGCCAATACAAGTGG	PDK1	ENSG00000152256	-0.652817732453544	[1101]	[419,206,148]	-6	hSpCas9	negative selection	9737236
172586372	172586395	2	-	27869803	ASPC1	viability after 36 days	ACATACCAGAGGCACTGCGCGGG	PDK1	ENSG00000152256	0.38559526085695844	[812]	[947,95,179]	4	hSpCas9	negative selection	9737237
172595859	172595882	2	-	27869803	ASPC1	viability after 36 days	CAGGCAGCTTTGTTATACACTGG	PDK1	ENSG00000152256	-0.09247651535434365	[1488]	[458,492,497]	-1	hSpCas9	negative selection	9737238
172556282	172556305	2	-	27869803	PATU8988S	viability after 35 days	AGCGCGCGTAGAAGTCCACCTGG	PDK1	ENSG00000152256	0.12622681626210408	[228]	[171,28,NaN]	1	hSpCas9	negative selection	9819682
172558828	172558851	2	+	27869803	PATU8988S	viability after 35 days	CCGTTCAATTGGTACAAAGCTGG	PDK1	ENSG00000152256	0.3430518294876639	[1159]	[636,547,NaN]	4	hSpCas9	negative selection	9819683
172564563	172564586	2	-	27869803	PATU8988S	viability after 35 days	CCTTGTATTCAATCACACCCTGG	PDK1	ENSG00000152256	0.23472545380726473	[649]	[325,289,NaN]	2	hSpCas9	negative selection	9819684
172568748	172568771	2	+	27869803	PATU8988S	viability after 35 days	ACCAGGACAGCCAATACAAGTGG	PDK1	ENSG00000152256	-0.24778172811538174	[845]	[267,305,NaN]	-3	hSpCas9	negative selection	9819685
172586372	172586395	2	-	27869803	PATU8988S	viability after 35 days	ACATACCAGAGGCACTGCGCGGG	PDK1	ENSG00000152256	0.9323784174241997	[716]	[593,507,NaN]	8	hSpCas9	negative selection	9819686
172595859	172595882	2	-	27869803	PATU8988S	viability after 35 days	CAGGCAGCTTTGTTATACACTGG	PDK1	ENSG00000152256	-0.16574909400059057	[1155]	[435,393,NaN]	-2	hSpCas9	negative selection	9819687
172556282	172556305	2	-	27869803	PATU8988S	viability after 31 days	AGCGCGCGTAGAAGTCCACCTGG	PDK1	ENSG00000152256	0.03522461558475354	[228]	[137,36,NaN]	0	hSpCas9	negative selection	9902131
172558828	172558851	2	+	27869803	PATU8988S	viability after 31 days	CCGTTCAATTGGTACAAAGCTGG	PDK1	ENSG00000152256	0.2319327008196752	[1159]	[412,708,NaN]	3	hSpCas9	negative selection	9902132
172564563	172564586	2	-	27869803	PATU8988S	viability after 31 days	CCTTGTATTCAATCACACCCTGG	PDK1	ENSG00000152256	0.4551452648224485	[649]	[353,356,NaN]	5	hSpCas9	negative selection	9902133
172568748	172568771	2	+	27869803	PATU8988S	viability after 31 days	ACCAGGACAGCCAATACAAGTGG	PDK1	ENSG00000152256	-0.7973077701954985	[845]	[150,248,NaN]	-7	hSpCas9	negative selection	9902134
172586372	172586395	2	-	27869803	PATU8988S	viability after 31 days	ACATACCAGAGGCACTGCGCGGG	PDK1	ENSG00000152256	0.6545208478032011	[716]	[409,500,NaN]	7	hSpCas9	negative selection	9902135
172595859	172595882	2	-	27869803	PATU8988S	viability after 31 days	CAGGCAGCTTTGTTATACACTGG	PDK1	ENSG00000152256	-0.6621898151805055	[1155]	[296,283,NaN]	-6	hSpCas9	negative selection	9902136
172556282	172556305	2	-	27869803	HPAFII	viability after 35 days	AGCGCGCGTAGAAGTCCACCTGG	PDK1	ENSG00000152256	0.1754692307209167	[123]	[92,45,NaN]	1	hSpCas9	negative selection	9984580
172558828	172558851	2	+	27869803	HPAFII	viability after 35 days	CCGTTCAATTGGTACAAAGCTGG	PDK1	ENSG00000152256	0.43978531885805694	[533]	[202,550,NaN]	3	hSpCas9	negative selection	9984581
172564563	172564586	2	-	27869803	HPAFII	viability after 35 days	CCTTGTATTCAATCACACCCTGG	PDK1	ENSG00000152256	0.4438911242003062	[406]	[236,328,NaN]	3	hSpCas9	negative selection	9984582
172568748	172568771	2	+	27869803	HPAFII	viability after 35 days	ACCAGGACAGCCAATACAAGTGG	PDK1	ENSG00000152256	-0.38673111271175353	[521]	[92,324,NaN]	-2	hSpCas9	negative selection	9984583
172586372	172586395	2	-	27869803	HPAFII	viability after 35 days	ACATACCAGAGGCACTGCGCGGG	PDK1	ENSG00000152256	-0.7437653419093347	[379]	[112,116,NaN]	-4	hSpCas9	negative selection	9984584
172595859	172595882	2	-	27869803	HPAFII	viability after 35 days	CAGGCAGCTTTGTTATACACTGG	PDK1	ENSG00000152256	-0.24208014289769642	[453]	[270,107,NaN]	-1	hSpCas9	negative selection	9984585
172556282	172556305	2	-	27869803	HPAFII	viability after 31 days	AGCGCGCGTAGAAGTCCACCTGG	PDK1	ENSG00000152256	-0.4449688633398481	[123]	[64,35,NaN]	-3	hSpCas9	negative selection	10067029
172558828	172558851	2	+	27869803	HPAFII	viability after 31 days	CCGTTCAATTGGTACAAAGCTGG	PDK1	ENSG00000152256	0.75348808224368	[533]	[342,681,NaN]	5	hSpCas9	negative selection	10067030
172564563	172564586	2	-	27869803	HPAFII	viability after 31 days	CCTTGTATTCAATCACACCCTGG	PDK1	ENSG00000152256	0.11943027296157838	[406]	[250,244,NaN]	0	hSpCas9	negative selection	10067031
172568748	172568771	2	+	27869803	HPAFII	viability after 31 days	ACCAGGACAGCCAATACAAGTGG	PDK1	ENSG00000152256	-0.6344203625676859	[521]	[148,231,NaN]	-4	hSpCas9	negative selection	10067032
172586372	172586395	2	-	27869803	HPAFII	viability after 31 days	ACATACCAGAGGCACTGCGCGGG	PDK1	ENSG00000152256	-1.4592966570713728	[379]	[89,63,NaN]	-7	hSpCas9	negative selection	10067033
172595859	172595882	2	-	27869803	HPAFII	viability after 31 days	CAGGCAGCTTTGTTATACACTGG	PDK1	ENSG00000152256	-0.12026060444111342	[453]	[198,272,NaN]	-1	hSpCas9	negative selection	10067034
172556212	172556235	2	-	28162770	P31FUJ	viability	GAAGCTGCGGCTGAAGCCGGCGG	PDK1	ENSG00000152256	0.2786981343657564	[46]	[66]	3	hSpCas9	negative selection	10209056
172556165	172556188	2	+	28162770	P31FUJ	viability	GCTGCTTCGCGGAGCCGCCTTGG	PDK1	ENSG00000152256	0.4880437243885507	[161]	[266]	5	hSpCas9	negative selection	10209057
172586275	172586298	2	+	28162770	P31FUJ	viability	TAGATGAGTGACCGAGGAGGTGG	PDK1	ENSG00000152256	0.14364004955188708	[160]	[208]	1	hSpCas9	negative selection	10209058
172586356	172586379	2	-	28162770	P31FUJ	viability	GCGCGGGAGGTCTCAACACGAGG	PDK1	ENSG00000152256	0.7006466026770153	[121]	[232]	7	hSpCas9	negative selection	10209059
172556143	172556166	2	+	28162770	P31FUJ	viability	GACTCGGCATGAGGCTGGCGCGG	PDK1	ENSG00000152256	1.849175097752231	[123]	[524]	9	hSpCas9	negative selection	10209060
172564578	172564601	2	+	28162770	P31FUJ	viability	ATACAAGGAGAGCTTTGGGGTGG	PDK1	ENSG00000152256	-0.44252079571571623	[169]	[146]	-4	hSpCas9	negative selection	10209061
172570744	172570767	2	+	28162770	P31FUJ	viability	ATGGAACACCATGCCAACAGAGG	PDK1	ENSG00000152256	-0.1790309479733978	[78]	[81]	-2	hSpCas9	negative selection	10209062
172556314	172556337	2	-	28162770	P31FUJ	viability	GAACTGCTTCATGGAGAGCGGGG	PDK1	ENSG00000152256	0.2478236364920421	[85]	[119]	2	hSpCas9	negative selection	10209063
172570779	172570802	2	+	28162770	P31FUJ	viability	TATTCAAGTTCATGTCACGCTGG	PDK1	ENSG00000152256	0.272662375992408	[142]	[202]	3	hSpCas9	negative selection	10209064
172586372	172586395	2	-	28162770	P31FUJ	viability	ACATACCAGAGGCACTGCGCGGG	PDK1	ENSG00000152256	-0.0723375322211326	[101]	[113]	0	hSpCas9	negative selection	10209065
172556212	172556235	2	-	28162770	TF1	viability	GAAGCTGCGGCTGAAGCCGGCGG	PDK1	ENSG00000152256	NaN	[NaN]	[61]	1	hSpCas9	negative selection	10378422
172556165	172556188	2	+	28162770	TF1	viability	GCTGCTTCGCGGAGCCGCCTTGG	PDK1	ENSG00000152256	NaN	[NaN]	[144]	1	hSpCas9	negative selection	10378423
172586275	172586298	2	+	28162770	TF1	viability	TAGATGAGTGACCGAGGAGGTGG	PDK1	ENSG00000152256	NaN	[NaN]	[265]	1	hSpCas9	negative selection	10378424
172586356	172586379	2	-	28162770	TF1	viability	GCGCGGGAGGTCTCAACACGAGG	PDK1	ENSG00000152256	NaN	[NaN]	[96]	1	hSpCas9	negative selection	10378425
172556143	172556166	2	+	28162770	TF1	viability	GACTCGGCATGAGGCTGGCGCGG	PDK1	ENSG00000152256	NaN	[NaN]	[183]	1	hSpCas9	negative selection	10378426
172564578	172564601	2	+	28162770	TF1	viability	ATACAAGGAGAGCTTTGGGGTGG	PDK1	ENSG00000152256	NaN	[NaN]	[61]	1	hSpCas9	negative selection	10378427
172570744	172570767	2	+	28162770	TF1	viability	ATGGAACACCATGCCAACAGAGG	PDK1	ENSG00000152256	NaN	[NaN]	[235]	1	hSpCas9	negative selection	10378428
172556314	172556337	2	-	28162770	TF1	viability	GAACTGCTTCATGGAGAGCGGGG	PDK1	ENSG00000152256	NaN	[NaN]	[18]	1	hSpCas9	negative selection	10378429
172570779	172570802	2	+	28162770	TF1	viability	TATTCAAGTTCATGTCACGCTGG	PDK1	ENSG00000152256	NaN	[NaN]	[342]	1	hSpCas9	negative selection	10378430
172586372	172586395	2	-	28162770	TF1	viability	ACATACCAGAGGCACTGCGCGGG	PDK1	ENSG00000152256	NaN	[NaN]	[81]	1	hSpCas9	negative selection	10378431
172556212	172556235	2	-	28162770	SKM1	viability	GAAGCTGCGGCTGAAGCCGGCGG	PDK1	ENSG00000152256	0.17799830197799427	[17]	[35]	1	hSpCas9	negative selection	10547788
172556165	172556188	2	+	28162770	SKM1	viability	GCTGCTTCGCGGAGCCGCCTTGG	PDK1	ENSG00000152256	0.6950567381973469	[28]	[82]	6	hSpCas9	negative selection	10547789
172586275	172586298	2	+	28162770	SKM1	viability	TAGATGAGTGACCGAGGAGGTGG	PDK1	ENSG00000152256	0.021879100060712697	[38]	[69]	0	hSpCas9	negative selection	10547790
172586356	172586379	2	-	28162770	SKM1	viability	GCGCGGGAGGTCTCAACACGAGG	PDK1	ENSG00000152256	0.30138071748327655	[27]	[60]	3	hSpCas9	negative selection	10547791
172556143	172556166	2	+	28162770	SKM1	viability	GACTCGGCATGAGGCTGGCGCGG	PDK1	ENSG00000152256	0.910714423142843	[33]	[112]	8	hSpCas9	negative selection	10547792
172564578	172564601	2	+	28162770	SKM1	viability	ATACAAGGAGAGCTTTGGGGTGG	PDK1	ENSG00000152256	0.6586241428844151	[42]	[119]	6	hSpCas9	negative selection	10547793
172570744	172570767	2	+	28162770	SKM1	viability	ATGGAACACCATGCCAACAGAGG	PDK1	ENSG00000152256	0.9582170940980848	[22]	[78]	8	hSpCas9	negative selection	10547794
172556314	172556337	2	-	28162770	SKM1	viability	GAACTGCTTCATGGAGAGCGGGG	PDK1	ENSG00000152256	0.8660542956632542	[26]	[86]	7	hSpCas9	negative selection	10547795
172570779	172570802	2	+	28162770	SKM1	viability	TATTCAAGTTCATGTCACGCTGG	PDK1	ENSG00000152256	0.5158679407343784	[35]	[90]	5	hSpCas9	negative selection	10547796
172586372	172586395	2	-	28162770	SKM1	viability	ACATACCAGAGGCACTGCGCGGG	PDK1	ENSG00000152256	0.4003907233144426	[20]	[48]	4	hSpCas9	negative selection	10547797
172556212	172556235	2	-	28162770	SKM1	viability	GAAGCTGCGGCTGAAGCCGGCGG	PDK1	ENSG00000152256	0.17799830197799427	[17]	[35]	1	hSpCas9	negative selection	10717154
172556165	172556188	2	+	28162770	SKM1	viability	GCTGCTTCGCGGAGCCGCCTTGG	PDK1	ENSG00000152256	0.6950567381973469	[28]	[82]	6	hSpCas9	negative selection	10717155
172586275	172586298	2	+	28162770	SKM1	viability	TAGATGAGTGACCGAGGAGGTGG	PDK1	ENSG00000152256	0.021879100060712697	[38]	[69]	0	hSpCas9	negative selection	10717156
172586356	172586379	2	-	28162770	SKM1	viability	GCGCGGGAGGTCTCAACACGAGG	PDK1	ENSG00000152256	0.30138071748327655	[27]	[60]	3	hSpCas9	negative selection	10717157
172556143	172556166	2	+	28162770	SKM1	viability	GACTCGGCATGAGGCTGGCGCGG	PDK1	ENSG00000152256	0.910714423142843	[33]	[112]	8	hSpCas9	negative selection	10717158
172564578	172564601	2	+	28162770	SKM1	viability	ATACAAGGAGAGCTTTGGGGTGG	PDK1	ENSG00000152256	0.6586241428844151	[42]	[119]	6	hSpCas9	negative selection	10717159
172570744	172570767	2	+	28162770	SKM1	viability	ATGGAACACCATGCCAACAGAGG	PDK1	ENSG00000152256	0.9582170940980848	[22]	[78]	8	hSpCas9	negative selection	10717160
172556314	172556337	2	-	28162770	SKM1	viability	GAACTGCTTCATGGAGAGCGGGG	PDK1	ENSG00000152256	0.8660542956632542	[26]	[86]	7	hSpCas9	negative selection	10717161
172570779	172570802	2	+	28162770	SKM1	viability	TATTCAAGTTCATGTCACGCTGG	PDK1	ENSG00000152256	0.5158679407343784	[35]	[90]	5	hSpCas9	negative selection	10717162
172586372	172586395	2	-	28162770	SKM1	viability	ACATACCAGAGGCACTGCGCGGG	PDK1	ENSG00000152256	0.4003907233144426	[20]	[48]	4	hSpCas9	negative selection	10717163
172556212	172556235	2	-	28162770	PL21	viability	GAAGCTGCGGCTGAAGCCGGCGG	PDK1	ENSG00000152256	-2.072878879917096	[86]	[8]	-8	hSpCas9	negative selection	10886520
172556165	172556188	2	+	28162770	PL21	viability	GCTGCTTCGCGGAGCCGCCTTGG	PDK1	ENSG00000152256	-0.29084673802282235	[103]	[36]	-2	hSpCas9	negative selection	10886521
172586275	172586298	2	+	28162770	PL21	viability	TAGATGAGTGACCGAGGAGGTGG	PDK1	ENSG00000152256	0.05996195644105984	[107]	[48]	0	hSpCas9	negative selection	10886522
172586356	172586379	2	-	28162770	PL21	viability	GCGCGGGAGGTCTCAACACGAGG	PDK1	ENSG00000152256	0.9404957978563004	[84]	[70]	7	hSpCas9	negative selection	10886523
172556143	172556166	2	+	28162770	PL21	viability	GACTCGGCATGAGGCTGGCGCGG	PDK1	ENSG00000152256	1.1872005587818222	[111]	[110]	8	hSpCas9	negative selection	10886524
172564578	172564601	2	+	28162770	PL21	viability	ATACAAGGAGAGCTTTGGGGTGG	PDK1	ENSG00000152256	-0.8786374988947969	[206]	[48]	-6	hSpCas9	negative selection	10886525
172570744	172570767	2	+	28162770	PL21	viability	ATGGAACACCATGCCAACAGAGG	PDK1	ENSG00000152256	-0.31832747444492926	[105]	[36]	-2	hSpCas9	negative selection	10886526
172556314	172556337	2	-	28162770	PL21	viability	GAACTGCTTCATGGAGAGCGGGG	PDK1	ENSG00000152256	-1.3675448948000004	[82]	[13]	-7	hSpCas9	negative selection	10886527
172570779	172570802	2	+	28162770	PL21	viability	TATTCAAGTTCATGTCACGCTGG	PDK1	ENSG00000152256	0.7280711701740975	[85]	[61]	6	hSpCas9	negative selection	10886528
172586372	172586395	2	-	28162770	PL21	viability	ACATACCAGAGGCACTGCGCGGG	PDK1	ENSG00000152256	0.6735937999934859	[120]	[83]	6	hSpCas9	negative selection	10886529
172556212	172556235	2	-	28162770	P31FUJ	viability	GAAGCTGCGGCTGAAGCCGGCGG	PDK1	ENSG00000152256	0.2786981343657564	[46]	[66]	3	hSpCas9	negative selection	11055886
172556165	172556188	2	+	28162770	P31FUJ	viability	GCTGCTTCGCGGAGCCGCCTTGG	PDK1	ENSG00000152256	0.4880437243885507	[161]	[266]	5	hSpCas9	negative selection	11055887
172586275	172586298	2	+	28162770	P31FUJ	viability	TAGATGAGTGACCGAGGAGGTGG	PDK1	ENSG00000152256	0.14364004955188708	[160]	[208]	1	hSpCas9	negative selection	11055888
172586356	172586379	2	-	28162770	P31FUJ	viability	GCGCGGGAGGTCTCAACACGAGG	PDK1	ENSG00000152256	0.7006466026770153	[121]	[232]	7	hSpCas9	negative selection	11055889
172556143	172556166	2	+	28162770	P31FUJ	viability	GACTCGGCATGAGGCTGGCGCGG	PDK1	ENSG00000152256	1.849175097752231	[123]	[524]	9	hSpCas9	negative selection	11055890
172564578	172564601	2	+	28162770	P31FUJ	viability	ATACAAGGAGAGCTTTGGGGTGG	PDK1	ENSG00000152256	-0.44252079571571623	[169]	[146]	-4	hSpCas9	negative selection	11055891
172570744	172570767	2	+	28162770	P31FUJ	viability	ATGGAACACCATGCCAACAGAGG	PDK1	ENSG00000152256	-0.1790309479733978	[78]	[81]	-2	hSpCas9	negative selection	11055892
172556314	172556337	2	-	28162770	P31FUJ	viability	GAACTGCTTCATGGAGAGCGGGG	PDK1	ENSG00000152256	0.2478236364920421	[85]	[119]	2	hSpCas9	negative selection	11055893
172570779	172570802	2	+	28162770	P31FUJ	viability	TATTCAAGTTCATGTCACGCTGG	PDK1	ENSG00000152256	0.272662375992408	[142]	[202]	3	hSpCas9	negative selection	11055894
172586372	172586395	2	-	28162770	P31FUJ	viability	ACATACCAGAGGCACTGCGCGGG	PDK1	ENSG00000152256	-0.0723375322211326	[101]	[113]	0	hSpCas9	negative selection	11055895
172556212	172556235	2	-	28162770	OCIAML5	viability	GAAGCTGCGGCTGAAGCCGGCGG	PDK1	ENSG00000152256	-1.5890321650302033	[34]	[20]	-7	hSpCas9	negative selection	11225252
172556165	172556188	2	+	28162770	OCIAML5	viability	GCTGCTTCGCGGAGCCGCCTTGG	PDK1	ENSG00000152256	0.22428431526611786	[91]	[193]	1	hSpCas9	negative selection	11225253
172586275	172586298	2	+	28162770	OCIAML5	viability	TAGATGAGTGACCGAGGAGGTGG	PDK1	ENSG00000152256	-0.0773588827062398	[82]	[141]	0	hSpCas9	negative selection	11225254
172586356	172586379	2	-	28162770	OCIAML5	viability	GCGCGGGAGGTCTCAACACGAGG	PDK1	ENSG00000152256	0.3301367603567522	[51]	[117]	3	hSpCas9	negative selection	11225255
172556143	172556166	2	+	28162770	OCIAML5	viability	GACTCGGCATGAGGCTGGCGCGG	PDK1	ENSG00000152256	0.1740857169919714	[81]	[166]	1	hSpCas9	negative selection	11225256
172564578	172564601	2	+	28162770	OCIAML5	viability	ATACAAGGAGAGCTTTGGGGTGG	PDK1	ENSG00000152256	-2.018424957286117	[100]	[44]	-8	hSpCas9	negative selection	11225257
172570744	172570767	2	+	28162770	OCIAML5	viability	ATGGAACACCATGCCAACAGAGG	PDK1	ENSG00000152256	0.6954212244384963	[64]	[189]	6	hSpCas9	negative selection	11225258
172556314	172556337	2	-	28162770	OCIAML5	viability	GAACTGCTTCATGGAGAGCGGGG	PDK1	ENSG00000152256	-0.5143711601183181	[90]	[114]	-4	hSpCas9	negative selection	11225259
172570779	172570802	2	+	28162770	OCIAML5	viability	TATTCAAGTTCATGTCACGCTGG	PDK1	ENSG00000152256	-0.9589817747805088	[83]	[77]	-6	hSpCas9	negative selection	11225260
172586372	172586395	2	-	28162770	OCIAML5	viability	ACATACCAGAGGCACTGCGCGGG	PDK1	ENSG00000152256	0.3446253401411008	[88]	[203]	3	hSpCas9	negative selection	11225261
172556212	172556235	2	-	28162770	EOL1	viability	GAAGCTGCGGCTGAAGCCGGCGG	PDK1	ENSG00000152256	0.0025502835718076433	[107]	[56]	0	hSpCas9	negative selection	11394618
172556165	172556188	2	+	28162770	EOL1	viability	GCTGCTTCGCGGAGCCGCCTTGG	PDK1	ENSG00000152256	1.2121243616671198	[135]	[165]	8	hSpCas9	negative selection	11394619
172586275	172586298	2	+	28162770	EOL1	viability	TAGATGAGTGACCGAGGAGGTGG	PDK1	ENSG00000152256	-0.911222832651156	[281]	[78]	-6	hSpCas9	negative selection	11394620
172586356	172586379	2	-	28162770	EOL1	viability	GCGCGGGAGGTCTCAACACGAGG	PDK1	ENSG00000152256	0.35031167744243696	[200]	[134]	3	hSpCas9	negative selection	11394621
172556143	172556166	2	+	28162770	EOL1	viability	GACTCGGCATGAGGCTGGCGCGG	PDK1	ENSG00000152256	-0.7525329311390531	[290]	[90]	-5	hSpCas9	negative selection	11394622
172564578	172564601	2	+	28162770	EOL1	viability	ATACAAGGAGAGCTTTGGGGTGG	PDK1	ENSG00000152256	0.26117237766459883	[292]	[184]	2	hSpCas9	negative selection	11394623
172570744	172570767	2	+	28162770	EOL1	viability	ATGGAACACCATGCCAACAGAGG	PDK1	ENSG00000152256	-0.25177500106992867	[112]	[49]	-2	hSpCas9	negative selection	11394624
172556314	172556337	2	-	28162770	EOL1	viability	GAACTGCTTCATGGAGAGCGGGG	PDK1	ENSG00000152256	-0.47538283531810066	[94]	[35]	-4	hSpCas9	negative selection	11394625
172570779	172570802	2	+	28162770	EOL1	viability	TATTCAAGTTCATGTCACGCTGG	PDK1	ENSG00000152256	0.3078764111220401	[137]	[89]	3	hSpCas9	negative selection	11394626
172586372	172586395	2	-	28162770	EOL1	viability	ACATACCAGAGGCACTGCGCGGG	PDK1	ENSG00000152256	0.04841942973270308	[144]	[78]	0	hSpCas9	negative selection	11394627
172556212	172556235	2	-	28162770	MOLM13	viability	GAAGCTGCGGCTGAAGCCGGCGG	PDK1	ENSG00000152256	-2.9145802552778344	[72]	[6]	-8	hSpCas9	negative selection	11563984
172556165	172556188	2	+	28162770	MOLM13	viability	GCTGCTTCGCGGAGCCGCCTTGG	PDK1	ENSG00000152256	0.7669430101793545	[177]	[218]	6	hSpCas9	negative selection	11563985
172586275	172586298	2	+	28162770	MOLM13	viability	TAGATGAGTGACCGAGGAGGTGG	PDK1	ENSG00000152256	1.1043421974554772	[210]	[327]	8	hSpCas9	negative selection	11563986
172586356	172586379	2	-	28162770	MOLM13	viability	GCGCGGGAGGTCTCAACACGAGG	PDK1	ENSG00000152256	1.0013215816256529	[113]	[164]	7	hSpCas9	negative selection	11563987
172556143	172556166	2	+	28162770	MOLM13	viability	GACTCGGCATGAGGCTGGCGCGG	PDK1	ENSG00000152256	0.5684933224829845	[179]	[192]	4	hSpCas9	negative selection	11563988
172564578	172564601	2	+	28162770	MOLM13	viability	ATACAAGGAGAGCTTTGGGGTGG	PDK1	ENSG00000152256	0.46788938154457876	[219]	[219]	3	hSpCas9	negative selection	11563989
172570744	172570767	2	+	28162770	MOLM13	viability	ATGGAACACCATGCCAACAGAGG	PDK1	ENSG00000152256	0.1592581092706742	[134]	[108]	1	hSpCas9	negative selection	11563990
172556314	172556337	2	-	28162770	MOLM13	viability	GAACTGCTTCATGGAGAGCGGGG	PDK1	ENSG00000152256	1.1988934174720682	[96]	[160]	8	hSpCas9	negative selection	11563991
172570779	172570802	2	+	28162770	MOLM13	viability	TATTCAAGTTCATGTCACGCTGG	PDK1	ENSG00000152256	0.4756667321362981	[184]	[185]	3	hSpCas9	negative selection	11563992
172586372	172586395	2	-	28162770	MOLM13	viability	ACATACCAGAGGCACTGCGCGGG	PDK1	ENSG00000152256	-0.32901875307790973	[171]	[98]	-2	hSpCas9	negative selection	11563993
172556212	172556235	2	-	28162770	HEL	viability	GAAGCTGCGGCTGAAGCCGGCGG	PDK1	ENSG00000152256	0.8568636373532044	[99]	[115]	7	hSpCas9	negative selection	11733350
172556165	172556188	2	+	28162770	HEL	viability	GCTGCTTCGCGGAGCCGCCTTGG	PDK1	ENSG00000152256	1.605264126581694	[155]	[303]	9	hSpCas9	negative selection	11733351
172586275	172586298	2	+	28162770	HEL	viability	TAGATGAGTGACCGAGGAGGTGG	PDK1	ENSG00000152256	-0.02996656336246528	[160]	[100]	0	hSpCas9	negative selection	11733352
172586356	172586379	2	-	28162770	HEL	viability	GCGCGGGAGGTCTCAACACGAGG	PDK1	ENSG00000152256	-0.11625306849584816	[131]	[77]	-1	hSpCas9	negative selection	11733353
172556143	172556166	2	+	28162770	HEL	viability	GACTCGGCATGAGGCTGGCGCGG	PDK1	ENSG00000152256	1.9612278429209482	[167]	[418]	9	hSpCas9	negative selection	11733354
172564578	172564601	2	+	28162770	HEL	viability	ATACAAGGAGAGCTTTGGGGTGG	PDK1	ENSG00000152256	-1.2257563848711512	[240]	[65]	-6	hSpCas9	negative selection	11733355
172570744	172570767	2	+	28162770	HEL	viability	ATGGAACACCATGCCAACAGAGG	PDK1	ENSG00000152256	-0.08388481794439007	[138]	[83]	0	hSpCas9	negative selection	11733356
172556314	172556337	2	-	28162770	HEL	viability	GAACTGCTTCATGGAGAGCGGGG	PDK1	ENSG00000152256	0.4071105835072151	[72]	[61]	3	hSpCas9	negative selection	11733357
172570779	172570802	2	+	28162770	HEL	viability	TATTCAAGTTCATGTCACGCTGG	PDK1	ENSG00000152256	0.6312431931625273	[125]	[124]	5	hSpCas9	negative selection	11733358
172586372	172586395	2	-	28162770	HEL	viability	ACATACCAGAGGCACTGCGCGGG	PDK1	ENSG00000152256	-0.3803447811126842	[125]	[61]	-3	hSpCas9	negative selection	11733359
172556212	172556235	2	-	28162770	MV411	viability	GAAGCTGCGGCTGAAGCCGGCGG	PDK1	ENSG00000152256	-0.06743578657063654	[50]	[40]	0	hSpCas9	negative selection	11902716
172556165	172556188	2	+	28162770	MV411	viability	GCTGCTTCGCGGAGCCGCCTTGG	PDK1	ENSG00000152256	-0.6843909465756453	[123]	[64]	-5	hSpCas9	negative selection	11902717
172586275	172586298	2	+	28162770	MV411	viability	TAGATGAGTGACCGAGGAGGTGG	PDK1	ENSG00000152256	1.3818638710037017	[127]	[280]	9	hSpCas9	negative selection	11902718
172586356	172586379	2	-	28162770	MV411	viability	GCGCGGGAGGTCTCAACACGAGG	PDK1	ENSG00000152256	0.8524656745580371	[118]	[180]	7	hSpCas9	negative selection	11902719
172556143	172556166	2	+	28162770	MV411	viability	GACTCGGCATGAGGCTGGCGCGG	PDK1	ENSG00000152256	0.4939495007039069	[160]	[190]	4	hSpCas9	negative selection	11902720
172564578	172564601	2	+	28162770	MV411	viability	ATACAAGGAGAGCTTTGGGGTGG	PDK1	ENSG00000152256	-0.2841755253454471	[145]	[100]	-2	hSpCas9	negative selection	11902721
172570744	172570767	2	+	28162770	MV411	viability	ATGGAACACCATGCCAACAGAGG	PDK1	ENSG00000152256	0.5182914610758684	[91]	[110]	4	hSpCas9	negative selection	11902722
172556314	172556337	2	-	28162770	MV411	viability	GAACTGCTTCATGGAGAGCGGGG	PDK1	ENSG00000152256	1.7213687391151877	[44]	[124]	9	hSpCas9	negative selection	11902723
172570779	172570802	2	+	28162770	MV411	viability	TATTCAAGTTCATGTCACGCTGG	PDK1	ENSG00000152256	1.103528139384062	[78]	[142]	8	hSpCas9	negative selection	11902724
172586372	172586395	2	-	28162770	MV411	viability	ACATACCAGAGGCACTGCGCGGG	PDK1	ENSG00000152256	0.08078768137332393	[109]	[97]	0	hSpCas9	negative selection	11902725
172556212	172556235	2	-	28162770	MONOMAC1	viability	GAAGCTGCGGCTGAAGCCGGCGG	PDK1	ENSG00000152256	-0.7022721553099758	[43]	[30]	-5	hSpCas9	negative selection	12072082
172556165	172556188	2	+	28162770	MONOMAC1	viability	GCTGCTTCGCGGAGCCGCCTTGG	PDK1	ENSG00000152256	0.8765442853215536	[85]	[180]	7	hSpCas9	negative selection	12072083
172586275	172586298	2	+	28162770	MONOMAC1	viability	TAGATGAGTGACCGAGGAGGTGG	PDK1	ENSG00000152256	-0.32680472202988337	[92]	[84]	-3	hSpCas9	negative selection	12072084
172586356	172586379	2	-	28162770	MONOMAC1	viability	GCGCGGGAGGTCTCAACACGAGG	PDK1	ENSG00000152256	-0.7085371858396887	[66]	[46]	-5	hSpCas9	negative selection	12072085
172556143	172556166	2	+	28162770	MONOMAC1	viability	GACTCGGCATGAGGCTGGCGCGG	PDK1	ENSG00000152256	-0.011821974592646334	[72]	[82]	0	hSpCas9	negative selection	12072086
172564578	172564601	2	+	28162770	MONOMAC1	viability	ATACAAGGAGAGCTTTGGGGTGG	PDK1	ENSG00000152256	-0.412049738030404	[129]	[111]	-4	hSpCas9	negative selection	12072087
172570744	172570767	2	+	28162770	MONOMAC1	viability	ATGGAACACCATGCCAACAGAGG	PDK1	ENSG00000152256	0.39732435166385205	[50]	[76]	4	hSpCas9	negative selection	12072088
172556314	172556337	2	-	28162770	MONOMAC1	viability	GAACTGCTTCATGGAGAGCGGGG	PDK1	ENSG00000152256	-1.9340024412257597	[49]	[14]	-8	hSpCas9	negative selection	12072089
172570779	172570802	2	+	28162770	MONOMAC1	viability	TATTCAAGTTCATGTCACGCTGG	PDK1	ENSG00000152256	0.7892882160433696	[52]	[104]	7	hSpCas9	negative selection	12072090
172586372	172586395	2	-	28162770	MONOMAC1	viability	ACATACCAGAGGCACTGCGCGGG	PDK1	ENSG00000152256	0.7370752172839893	[55]	[106]	7	hSpCas9	negative selection	12072091
172556212	172556235	2	-	28162770	OCIAML2	viability	GAAGCTGCGGCTGAAGCCGGCGG	PDK1	ENSG00000152256	-1.1487017303547988	[7]	[19]	-6	hSpCas9	negative selection	12241448
172556165	172556188	2	+	28162770	OCIAML2	viability	GCTGCTTCGCGGAGCCGCCTTGG	PDK1	ENSG00000152256	1.0476954824487046	[23]	[274]	8	hSpCas9	negative selection	12241449
172586275	172586298	2	+	28162770	OCIAML2	viability	TAGATGAGTGACCGAGGAGGTGG	PDK1	ENSG00000152256	1.1381794174333628	[19]	[243]	9	hSpCas9	negative selection	12241450
172586356	172586379	2	-	28162770	OCIAML2	viability	GCGCGGGAGGTCTCAACACGAGG	PDK1	ENSG00000152256	-0.20759541940836734	[19]	[95]	-2	hSpCas9	negative selection	12241451
172556143	172556166	2	+	28162770	OCIAML2	viability	GACTCGGCATGAGGCTGGCGCGG	PDK1	ENSG00000152256	0.35534077498279	[21]	[155]	3	hSpCas9	negative selection	12241452
172564578	172564601	2	+	28162770	OCIAML2	viability	ATACAAGGAGAGCTTTGGGGTGG	PDK1	ENSG00000152256	-0.20592659904774874	[35]	[172]	-2	hSpCas9	negative selection	12241453
172570744	172570767	2	+	28162770	OCIAML2	viability	ATGGAACACCATGCCAACAGAGG	PDK1	ENSG00000152256	0.1833743199086464	[16]	[106]	1	hSpCas9	negative selection	12241454
172556314	172556337	2	-	28162770	OCIAML2	viability	GAACTGCTTCATGGAGAGCGGGG	PDK1	ENSG00000152256	0.5688985389444763	[17]	[147]	5	hSpCas9	negative selection	12241455
172570779	172570802	2	+	28162770	OCIAML2	viability	TATTCAAGTTCATGTCACGCTGG	PDK1	ENSG00000152256	0.8608843184743993	[14]	[150]	8	hSpCas9	negative selection	12241456
172586372	172586395	2	-	28162770	OCIAML2	viability	ACATACCAGAGGCACTGCGCGGG	PDK1	ENSG00000152256	-1.0783124024634008	[23]	[62]	-6	hSpCas9	negative selection	12241457
172556212	172556235	2	-	28162770	OCIAML3	viability	GAAGCTGCGGCTGAAGCCGGCGG	PDK1	ENSG00000152256	-1.2016902175454027	[15]	[20]	-7	hSpCas9	negative selection	12410814
172556165	172556188	2	+	28162770	OCIAML3	viability	GCTGCTTCGCGGAGCCGCCTTGG	PDK1	ENSG00000152256	0.9528868195634734	[31]	[186]	8	hSpCas9	negative selection	12410815
172586275	172586298	2	+	28162770	OCIAML3	viability	TAGATGAGTGACCGAGGAGGTGG	PDK1	ENSG00000152256	1.5198833262038214	[34]	[302]	9	hSpCas9	negative selection	12410816
172586356	172586379	2	-	28162770	OCIAML3	viability	GCGCGGGAGGTCTCAACACGAGG	PDK1	ENSG00000152256	0.07584375798350607	[32]	[104]	0	hSpCas9	negative selection	12410817
172556143	172556166	2	+	28162770	OCIAML3	viability	GACTCGGCATGAGGCTGGCGCGG	PDK1	ENSG00000152256	0.8978454560055115	[23]	[134]	7	hSpCas9	negative selection	12410818
172564578	172564601	2	+	28162770	OCIAML3	viability	ATACAAGGAGAGCTTTGGGGTGG	PDK1	ENSG00000152256	0.7339191951846422	[47]	[240]	6	hSpCas9	negative selection	12410819
172570744	172570767	2	+	28162770	OCIAML3	viability	ATGGAACACCATGCCAACAGAGG	PDK1	ENSG00000152256	-0.17367584137580627	[33]	[90]	-1	hSpCas9	negative selection	12410820
172556314	172556337	2	-	28162770	OCIAML3	viability	GAACTGCTTCATGGAGAGCGGGG	PDK1	ENSG00000152256	0.053690615744955705	[14]	[46]	0	hSpCas9	negative selection	12410821
172570779	172570802	2	+	28162770	OCIAML3	viability	TATTCAAGTTCATGTCACGCTGG	PDK1	ENSG00000152256	-0.5565329349055004	[37]	[77]	-4	hSpCas9	negative selection	12410822
172586372	172586395	2	-	28162770	OCIAML3	viability	ACATACCAGAGGCACTGCGCGGG	PDK1	ENSG00000152256	-0.3569684430233139	[27]	[65]	-3	hSpCas9	negative selection	12410823