Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:5311
• Symbol:Pkd2
• Description:polycystin 2, transient receptor potential cation channel

DataSource: http://genomecrispr.dkfz.de/#!/results/Pkd2

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
88007898	88007921	4	+	26472758	Jiyoye	viability	GATGCAGCGCATCCGGCAGGCGG	PKD2	ENSG00000118762	0.40717538150587274	[0]	[0]	3	hSpCas9	negative selection	121218
88074932	88074955	4	+	26472758	Jiyoye	viability	GGGAAGGCTGTTGGATGGGGTGG	PKD2	ENSG00000118762	-0.5224352906027288	[199]	[104]	-4	hSpCas9	negative selection	121219
88007962	88007985	4	-	26472758	Jiyoye	viability	CGGGAGCACGACGAGAGCGGAGG	PKD2	ENSG00000118762	0.2036419874207412	[75]	[65]	1	hSpCas9	negative selection	121220
88008034	88008057	4	+	26472758	Jiyoye	viability	GAGGAGGTGGAAGGGGAAGAAGG	PKD2	ENSG00000118762	-7.092670505577332	[180]	[0]	-9	hSpCas9	negative selection	121221
88043317	88043340	4	+	26472758	Jiyoye	viability	GGATTTGTCAAGAACAAGAGAGG	PKD2	ENSG00000118762	1.4489955572005007	[67]	[139]	8	hSpCas9	negative selection	121222
88043394	88043417	4	-	26472758	Jiyoye	viability	GAAGTCAATAAAAGTTGCCCTGG	PKD2	ENSG00000118762	0.5394826736100037	[176]	[193]	4	hSpCas9	negative selection	121223
88065431	88065454	4	+	26472758	Jiyoye	viability	TCAGAGAGTCTGCGGCAAGGAGG	PKD2	ENSG00000118762	0.4449774142182578	[112]	[115]	3	hSpCas9	negative selection	121224
88065857	88065880	4	+	26472758	Jiyoye	viability	GAGACGACTTGGAGAAAGAGAGG	PKD2	ENSG00000118762	0.2771148409415006	[115]	[105]	2	hSpCas9	negative selection	121225
88068000	88068023	4	+	26472758	Jiyoye	viability	GGACATAGCTCCAGAAGGAGGGG	PKD2	ENSG00000118762	2.4642063265422522	[30]	[128]	9	hSpCas9	negative selection	121226
88074901	88074924	4	+	26472758	Jiyoye	viability	AGCGAGCCAAACTGAAGAGGAGG	PKD2	ENSG00000118762	0.4071753815058733	[99]	[99]	3	hSpCas9	negative selection	121227
88007898	88007921	4	+	26472758	KBM7	viability	GATGCAGCGCATCCGGCAGGCGG	PKD2	ENSG00000118762	0.8998430751727007	[0,11]	[1,9]	8	hSpCas9	negative selection	312336
88074932	88074955	4	+	26472758	KBM7	viability	GGGAAGGCTGTTGGATGGGGTGG	PKD2	ENSG00000118762	-0.5132285308307192	[499,483]	[188,138]	-4	hSpCas9	negative selection	312337
88007962	88007985	4	-	26472758	KBM7	viability	CGGGAGCACGACGAGAGCGGAGG	PKD2	ENSG00000118762	0.19632649226078963	[548,321]	[219,237]	2	hSpCas9	negative selection	312338
88008034	88008057	4	+	26472758	KBM7	viability	GAGGAGGTGGAAGGGGAAGAAGG	PKD2	ENSG00000118762	-4.541331890082003	[928,643]	[21,9]	-9	hSpCas9	negative selection	312339
88043317	88043340	4	+	26472758	KBM7	viability	GGATTTGTCAAGAACAAGAGAGG	PKD2	ENSG00000118762	-0.3043706068600557	[785,389]	[183,246]	-3	hSpCas9	negative selection	312340
88043394	88043417	4	-	26472758	KBM7	viability	GAAGTCAATAAAAGTTGCCCTGG	PKD2	ENSG00000118762	0.37908932935301176	[866,403]	[422,333]	4	hSpCas9	negative selection	312341
88065431	88065454	4	+	26472758	KBM7	viability	TCAGAGAGTCTGCGGCAAGGAGG	PKD2	ENSG00000118762	0.3821527386415023	[747,574]	[346,450]	4	hSpCas9	negative selection	312342
88065857	88065880	4	+	26472758	KBM7	viability	GAGACGACTTGGAGAAAGAGAGG	PKD2	ENSG00000118762	-0.30250851815877544	[510,514]	[203,189]	-3	hSpCas9	negative selection	312343
88068000	88068023	4	+	26472758	KBM7	viability	GGACATAGCTCCAGAAGGAGGGG	PKD2	ENSG00000118762	0.32629653228379296	[269,313]	[262,94]	3	hSpCas9	negative selection	312344
88074901	88074924	4	+	26472758	KBM7	viability	AGCGAGCCAAACTGAAGAGGAGG	PKD2	ENSG00000118762	0.41245172390469154	[371,293]	[236,179]	4	hSpCas9	negative selection	312345
88007898	88007921	4	+	26472758	Raji	viability	GATGCAGCGCATCCGGCAGGCGG	PKD2	ENSG00000118762	2.1073835353735992	[0]	[0]	9	hSpCas9	negative selection	503454
88074932	88074955	4	+	26472758	Raji	viability	GGGAAGGCTGTTGGATGGGGTGG	PKD2	ENSG00000118762	-1.6847368729888443	[470]	[33]	-8	hSpCas9	negative selection	503455
88007962	88007985	4	-	26472758	Raji	viability	CGGGAGCACGACGAGAGCGGAGG	PKD2	ENSG00000118762	-0.10120308643781797	[207]	[44]	-1	hSpCas9	negative selection	503456
88008034	88008057	4	+	26472758	Raji	viability	GAGGAGGTGGAAGGGGAAGAAGG	PKD2	ENSG00000118762	-3.137376698991303	[454]	[11]	-9	hSpCas9	negative selection	503457
88043317	88043340	4	+	26472758	Raji	viability	GGATTTGTCAAGAACAAGAGAGG	PKD2	ENSG00000118762	0.6309454914306125	[191]	[68]	6	hSpCas9	negative selection	503458
88043394	88043417	4	-	26472758	Raji	viability	GAAGTCAATAAAAGTTGCCCTGG	PKD2	ENSG00000118762	0.2158553246317888	[396]	[106]	2	hSpCas9	negative selection	503459
88065431	88065454	4	+	26472758	Raji	viability	TCAGAGAGTCTGCGGCAAGGAGG	PKD2	ENSG00000118762	0.4909713960273909	[370]	[120]	4	hSpCas9	negative selection	503460
88065857	88065880	4	+	26472758	Raji	viability	GAGACGACTTGGAGAAAGAGAGG	PKD2	ENSG00000118762	0.9686194654177478	[228]	[103]	8	hSpCas9	negative selection	503461
88068000	88068023	4	+	26472758	Raji	viability	GGACATAGCTCCAGAAGGAGGGG	PKD2	ENSG00000118762	-0.287476081967614	[141]	[26]	-2	hSpCas9	negative selection	503462
88074901	88074924	4	+	26472758	Raji	viability	AGCGAGCCAAACTGAAGAGGAGG	PKD2	ENSG00000118762	-0.6999713866840047	[188]	[26]	-5	hSpCas9	negative selection	503463
88007898	88007921	4	+	26472758	K562	viability	GATGCAGCGCATCCGGCAGGCGG	PKD2	ENSG00000118762	5.859128571781655	[0]	[48]	9	hSpCas9	negative selection	694572
88074932	88074955	4	+	26472758	K562	viability	GGGAAGGCTGTTGGATGGGGTGG	PKD2	ENSG00000118762	-1.5013977840820247	[435]	[129]	-6	hSpCas9	negative selection	694573
88007962	88007985	4	-	26472758	K562	viability	CGGGAGCACGACGAGAGCGGAGG	PKD2	ENSG00000118762	1.2960514960817693	[246]	[511]	9	hSpCas9	negative selection	694574
88008034	88008057	4	+	26472758	K562	viability	GAGGAGGTGGAAGGGGAAGAAGG	PKD2	ENSG00000118762	-9.119715927341604	[658]	[0]	-9	hSpCas9	negative selection	694575
88043317	88043340	4	+	26472758	K562	viability	GGATTTGTCAAGAACAAGAGAGG	PKD2	ENSG00000118762	0.1670853692211815	[478]	[453]	1	hSpCas9	negative selection	694576
88043394	88043417	4	-	26472758	K562	viability	GAAGTCAATAAAAGTTGCCCTGG	PKD2	ENSG00000118762	0.46052830819287394	[525]	[610]	3	hSpCas9	negative selection	694577
88065431	88065454	4	+	26472758	K562	viability	TCAGAGAGTCTGCGGCAAGGAGG	PKD2	ENSG00000118762	0.2676261188277722	[739]	[751]	2	hSpCas9	negative selection	694578
88065857	88065880	4	+	26472758	K562	viability	GAGACGACTTGGAGAAAGAGAGG	PKD2	ENSG00000118762	1.5272410315562182	[530]	[1291]	9	hSpCas9	negative selection	694579
88068000	88068023	4	+	26472758	K562	viability	GGACATAGCTCCAGAAGGAGGGG	PKD2	ENSG00000118762	1.485426827170242	[241]	[571]	9	hSpCas9	negative selection	694580
88074901	88074924	4	+	26472758	K562	viability	AGCGAGCCAAACTGAAGAGGAGG	PKD2	ENSG00000118762	0.5382760569671409	[300]	[368]	4	hSpCas9	negative selection	694581
88008073	88008096	4	+	26627737	DLD1	viability	ATGGACGTAGAGTGGCGCCCGGG	PKD2	ENSG00000118762	-0.764389309819315	[343]	[69,46,70]	-6	hSpCas9	negative selection	826170
88038371	88038394	4	+	26627737	DLD1	viability	CGGCAACTCCGAGTCAGAAATGG	PKD2	ENSG00000118762	0.7851921411266216	[1298]	[700,795,618]	7	hSpCas9	negative selection	826171
88043376	88043399	4	+	26627737	DLD1	viability	TCTGGCTGGACCGAGGAACCAGG	PKD2	ENSG00000118762	0.35344283730675446	[586]	[429,179,109]	3	hSpCas9	negative selection	826172
88056217	88056240	4	-	26627737	DLD1	viability	CGACCTGAGTGCCAAAGACAAGG	PKD2	ENSG00000118762	0.3197249983429282	[3226]	[1172,1354,1253]	3	hSpCas9	negative selection	826173
88065857	88065880	4	+	26627737	DLD1	viability	GAGACGACTTGGAGAAAGAGAGG	PKD2	ENSG00000118762	0.8445081695054522	[125]	[59,141,20]	7	hSpCas9	negative selection	826174
88067995	88068018	4	+	26627737	DLD1	viability	ATAGCGGACATAGCTCCAGAAGG	PKD2	ENSG00000118762	-0.32932093217003366	[248]	[71,118,5]	-3	hSpCas9	negative selection	826175
88008073	88008096	4	+	26627737	GBM cells	viability after 5 days	ATGGACGTAGAGTGGCGCCCGGG	PKD2	ENSG00000118762	0.41217491025265307	[109]	[90,65]	6	hSpCas9	negative selection	908485
88038371	88038394	4	+	26627737	GBM cells	viability after 5 days	CGGCAACTCCGAGTCAGAAATGG	PKD2	ENSG00000118762	0.3559931449814553	[836]	[559,588]	5	hSpCas9	negative selection	908486
88043376	88043399	4	+	26627737	GBM cells	viability after 5 days	TCTGGCTGGACCGAGGAACCAGG	PKD2	ENSG00000118762	0.13655512329108188	[362]	[233,193]	2	hSpCas9	negative selection	908487
88056217	88056240	4	-	26627737	GBM cells	viability after 5 days	CGACCTGAGTGCCAAAGACAAGG	PKD2	ENSG00000118762	0.0916624720073238	[1741]	[1015,974]	1	hSpCas9	negative selection	908488
88065857	88065880	4	+	26627737	GBM cells	viability after 5 days	GAGACGACTTGGAGAAAGAGAGG	PKD2	ENSG00000118762	0.5484166278015522	[101]	[80,78]	7	hSpCas9	negative selection	908489
88067995	88068018	4	+	26627737	GBM cells	viability after 5 days	ATAGCGGACATAGCTCCAGAAGG	PKD2	ENSG00000118762	0.32890171563050086	[143]	[116,76]	5	hSpCas9	negative selection	908490
88008073	88008096	4	+	26627737	GBM cells	viability after 13 days	ATGGACGTAGAGTGGCGCCCGGG	PKD2	ENSG00000118762	0.45790726300613693	[109]	[108,59]	6	hSpCas9	negative selection	990800
88038371	88038394	4	+	26627737	GBM cells	viability after 13 days	CGGCAACTCCGAGTCAGAAATGG	PKD2	ENSG00000118762	0.3130031964376838	[836]	[631,508]	4	hSpCas9	negative selection	990801
88043376	88043399	4	+	26627737	GBM cells	viability after 13 days	TCTGGCTGGACCGAGGAACCAGG	PKD2	ENSG00000118762	0.26585641234188584	[362]	[270,208]	3	hSpCas9	negative selection	990802
88056217	88056240	4	-	26627737	GBM cells	viability after 13 days	CGACCTGAGTGCCAAAGACAAGG	PKD2	ENSG00000118762	0.05476448698904601	[1741]	[1230,778]	0	hSpCas9	negative selection	990803
88065857	88065880	4	+	26627737	GBM cells	viability after 13 days	GAGACGACTTGGAGAAAGAGAGG	PKD2	ENSG00000118762	0.4383550244787292	[101]	[58,87]	5	hSpCas9	negative selection	990804
88067995	88068018	4	+	26627737	GBM cells	viability after 13 days	ATAGCGGACATAGCTCCAGAAGG	PKD2	ENSG00000118762	0.07154012166610324	[143]	[80,82]	0	hSpCas9	negative selection	990805
88008073	88008096	4	+	26627737	GBM cells	viability after 21 days	ATGGACGTAGAGTGGCGCCCGGG	PKD2	ENSG00000118762	-0.2550277755233168	[109]	[59,40]	-2	hSpCas9	negative selection	1073115
88038371	88038394	4	+	26627737	GBM cells	viability after 21 days	CGGCAACTCCGAGTCAGAAATGG	PKD2	ENSG00000118762	0.5268921015334105	[836]	[650,658]	5	hSpCas9	negative selection	1073116
88043376	88043399	4	+	26627737	GBM cells	viability after 21 days	TCTGGCTGGACCGAGGAACCAGG	PKD2	ENSG00000118762	0.47876241709931955	[362]	[278,270]	5	hSpCas9	negative selection	1073117
88056217	88056240	4	-	26627737	GBM cells	viability after 21 days	CGACCTGAGTGCCAAAGACAAGG	PKD2	ENSG00000118762	0.11775315345270121	[1741]	[1064,991]	1	hSpCas9	negative selection	1073118
88065857	88065880	4	+	26627737	GBM cells	viability after 21 days	GAGACGACTTGGAGAAAGAGAGG	PKD2	ENSG00000118762	0.8259487071596445	[101]	[80,113]	7	hSpCas9	negative selection	1073119
88067995	88068018	4	+	26627737	GBM cells	viability after 21 days	ATAGCGGACATAGCTCCAGAAGG	PKD2	ENSG00000118762	0.8640010600226109	[143]	[144,139]	8	hSpCas9	negative selection	1073120
88008073	88008096	4	+	26627737	RPE1	viability after 9 days	ATGGACGTAGAGTGGCGCCCGGG	PKD2	ENSG00000118762	-1.3706092861476367	[831]	[153,31]	-7	hSpCas9	negative selection	1155430
88038371	88038394	4	+	26627737	RPE1	viability after 9 days	CGGCAACTCCGAGTCAGAAATGG	PKD2	ENSG00000118762	1.6449716337134268	[1848]	[1643,2024]	8	hSpCas9	negative selection	1155431
88043376	88043399	4	+	26627737	RPE1	viability after 9 days	TCTGGCTGGACCGAGGAACCAGG	PKD2	ENSG00000118762	0.4702530614229763	[706]	[248,380]	3	hSpCas9	negative selection	1155432
88056217	88056240	4	-	26627737	RPE1	viability after 9 days	CGACCTGAGTGCCAAAGACAAGG	PKD2	ENSG00000118762	0.1653769580391682	[3664]	[857,1839]	1	hSpCas9	negative selection	1155433
88065857	88065880	4	+	26627737	RPE1	viability after 9 days	GAGACGACTTGGAGAAAGAGAGG	PKD2	ENSG00000118762	0.6083323344562828	[307]	[177,106]	4	hSpCas9	negative selection	1155434
88067995	88068018	4	+	26627737	RPE1	viability after 9 days	ATAGCGGACATAGCTCCAGAAGG	PKD2	ENSG00000118762	0.3162874822883351	[679]	[144,419]	2	hSpCas9	negative selection	1155435
88008073	88008096	4	+	26627737	RPE1	viability after 12 days	ATGGACGTAGAGTGGCGCCCGGG	PKD2	ENSG00000118762	-1.848138864231638	[831]	[64,58]	-8	hSpCas9	negative selection	1237745
88038371	88038394	4	+	26627737	RPE1	viability after 12 days	CGGCAACTCCGAGTCAGAAATGG	PKD2	ENSG00000118762	1.7838927285647597	[1848]	[1425,2011]	8	hSpCas9	negative selection	1237746
88043376	88043399	4	+	26627737	RPE1	viability after 12 days	TCTGGCTGGACCGAGGAACCAGG	PKD2	ENSG00000118762	0.39682384504979884	[706]	[218,282]	2	hSpCas9	negative selection	1237747
88056217	88056240	4	-	26627737	RPE1	viability after 12 days	CGACCTGAGTGCCAAAGACAAGG	PKD2	ENSG00000118762	0.45656995235529685	[3664]	[1001,1720]	3	hSpCas9	negative selection	1237748
88065857	88065880	4	+	26627737	RPE1	viability after 12 days	GAGACGACTTGGAGAAAGAGAGG	PKD2	ENSG00000118762	0.8652707032848148	[307]	[107,195]	5	hSpCas9	negative selection	1237749
88067995	88068018	4	+	26627737	RPE1	viability after 12 days	ATAGCGGACATAGCTCCAGAAGG	PKD2	ENSG00000118762	-0.3291126004464726	[679]	[57,237]	-2	hSpCas9	negative selection	1237750
88008073	88008096	4	+	26627737	RPE1	viability after 15 days	ATGGACGTAGAGTGGCGCCCGGG	PKD2	ENSG00000118762	-1.854767185957062	[831]	[32,95]	-8	hSpCas9	negative selection	1320060
88038371	88038394	4	+	26627737	RPE1	viability after 15 days	CGGCAACTCCGAGTCAGAAATGG	PKD2	ENSG00000118762	1.9055225364689263	[1848]	[1956,1961]	8	hSpCas9	negative selection	1320061
88043376	88043399	4	+	26627737	RPE1	viability after 15 days	TCTGGCTGGACCGAGGAACCAGG	PKD2	ENSG00000118762	-0.23609797073071212	[706]	[208,131]	-1	hSpCas9	negative selection	1320062
88056217	88056240	4	-	26627737	RPE1	viability after 15 days	CGACCTGAGTGCCAAAGACAAGG	PKD2	ENSG00000118762	0.35534380003571986	[3664]	[1224,1423]	2	hSpCas9	negative selection	1320063
88065857	88065880	4	+	26627737	RPE1	viability after 15 days	GAGACGACTTGGAGAAAGAGAGG	PKD2	ENSG00000118762	0.4976625835626318	[307]	[93,150]	3	hSpCas9	negative selection	1320064
88067995	88068018	4	+	26627737	RPE1	viability after 15 days	ATAGCGGACATAGCTCCAGAAGG	PKD2	ENSG00000118762	-0.5741899078071114	[679]	[117,139]	-4	hSpCas9	negative selection	1320065
88008073	88008096	4	+	26627737	RPE1	viability after 18 days	ATGGACGTAGAGTGGCGCCCGGG	PKD2	ENSG00000118762	-2.5236171196514867	[831]	[54,21]	-8	hSpCas9	negative selection	1402375
88038371	88038394	4	+	26627737	RPE1	viability after 18 days	CGGCAACTCCGAGTCAGAAATGG	PKD2	ENSG00000118762	1.6193253332135547	[1848]	[1548,1515]	8	hSpCas9	negative selection	1402376
88043376	88043399	4	+	26627737	RPE1	viability after 18 days	TCTGGCTGGACCGAGGAACCAGG	PKD2	ENSG00000118762	-0.33876182827261037	[706]	[146,154]	-2	hSpCas9	negative selection	1402377
88056217	88056240	4	-	26627737	RPE1	viability after 18 days	CGACCTGAGTGCCAAAGACAAGG	PKD2	ENSG00000118762	0.4874678713138745	[3664]	[1230,1552]	3	hSpCas9	negative selection	1402378
88065857	88065880	4	+	26627737	RPE1	viability after 18 days	GAGACGACTTGGAGAAAGAGAGG	PKD2	ENSG00000118762	0.8935257950477096	[307]	[180,125]	5	hSpCas9	negative selection	1402379
88067995	88068018	4	+	26627737	RPE1	viability after 18 days	ATAGCGGACATAGCTCCAGAAGG	PKD2	ENSG00000118762	-1.022788460688378	[679]	[84,95]	-6	hSpCas9	negative selection	1402380
88008073	88008096	4	+	26627737	HeLa	viability after 8 days	ATGGACGTAGAGTGGCGCCCGGG	PKD2	ENSG00000118762	-1.4354936107743261	[570]	[140,17,124]	-9	hSpCas9	negative selection	1484690
88038371	88038394	4	+	26627737	HeLa	viability after 8 days	CGGCAACTCCGAGTCAGAAATGG	PKD2	ENSG00000118762	-0.13465096427921264	[1889]	[782,769,704]	-1	hSpCas9	negative selection	1484691
88043376	88043399	4	+	26627737	HeLa	viability after 8 days	TCTGGCTGGACCGAGGAACCAGG	PKD2	ENSG00000118762	0.08846409114486176	[677]	[415,447,113]	0	hSpCas9	negative selection	1484692
88056217	88056240	4	-	26627737	HeLa	viability after 8 days	CGACCTGAGTGCCAAAGACAAGG	PKD2	ENSG00000118762	0.19214001055559793	[2665]	[1410,1349,1239]	1	hSpCas9	negative selection	1484693
88065857	88065880	4	+	26627737	HeLa	viability after 8 days	GAGACGACTTGGAGAAAGAGAGG	PKD2	ENSG00000118762	0.12750441606604557	[239]	[209,33,118]	1	hSpCas9	negative selection	1484694
88067995	88068018	4	+	26627737	HeLa	viability after 8 days	ATAGCGGACATAGCTCCAGAAGG	PKD2	ENSG00000118762	1.2081039968804472	[167]	[140,78,272]	8	hSpCas9	negative selection	1484695
88008073	88008096	4	+	26627737	HeLa	viability after 12 days	ATGGACGTAGAGTGGCGCCCGGG	PKD2	ENSG00000118762	-1.6642740363283672	[570]	[95,111,11]	-9	hSpCas9	negative selection	1567005
88038371	88038394	4	+	26627737	HeLa	viability after 12 days	CGGCAACTCCGAGTCAGAAATGG	PKD2	ENSG00000118762	-0.2683320755356884	[1889]	[778,575,601]	-2	hSpCas9	negative selection	1567006
88043376	88043399	4	+	26627737	HeLa	viability after 12 days	TCTGGCTGGACCGAGGAACCAGG	PKD2	ENSG00000118762	-0.3801033032417938	[677]	[184,120,348]	-3	hSpCas9	negative selection	1567007
88056217	88056240	4	-	26627737	HeLa	viability after 12 days	CGACCTGAGTGCCAAAGACAAGG	PKD2	ENSG00000118762	0.09982962802780859	[2665]	[1604,1099,857]	0	hSpCas9	negative selection	1567008
88065857	88065880	4	+	26627737	HeLa	viability after 12 days	GAGACGACTTGGAGAAAGAGAGG	PKD2	ENSG00000118762	-0.14251535605986698	[239]	[65,31,176]	-1	hSpCas9	negative selection	1567009
88067995	88068018	4	+	26627737	HeLa	viability after 12 days	ATAGCGGACATAGCTCCAGAAGG	PKD2	ENSG00000118762	0.6351210539788618	[167]	[128,70,127]	5	hSpCas9	negative selection	1567010
88008073	88008096	4	+	26627737	HeLa	viability after 15 days	ATGGACGTAGAGTGGCGCCCGGG	PKD2	ENSG00000118762	-1.5012599543541207	[570]	[106,32,107]	-8	hSpCas9	negative selection	1649320
88038371	88038394	4	+	26627737	HeLa	viability after 15 days	CGGCAACTCCGAGTCAGAAATGG	PKD2	ENSG00000118762	-0.4228594451365728	[1889]	[482,617,625]	-4	hSpCas9	negative selection	1649321
88043376	88043399	4	+	26627737	HeLa	viability after 15 days	TCTGGCTGGACCGAGGAACCAGG	PKD2	ENSG00000118762	-0.030792114116401592	[677]	[406,104,298]	0	hSpCas9	negative selection	1649322
88056217	88056240	4	-	26627737	HeLa	viability after 15 days	CGACCTGAGTGCCAAAGACAAGG	PKD2	ENSG00000118762	0.1268595862980737	[2665]	[1208,1534,779]	1	hSpCas9	negative selection	1649323
88065857	88065880	4	+	26627737	HeLa	viability after 15 days	GAGACGACTTGGAGAAAGAGAGG	PKD2	ENSG00000118762	-0.13739630317542106	[239]	[71,53,144]	-1	hSpCas9	negative selection	1649324
88067995	88068018	4	+	26627737	HeLa	viability after 15 days	ATAGCGGACATAGCTCCAGAAGG	PKD2	ENSG00000118762	1.1502092774332275	[167]	[220,135,92]	7	hSpCas9	negative selection	1649325
88008073	88008096	4	+	26627737	HeLa	viability after 18 days	ATGGACGTAGAGTGGCGCCCGGG	PKD2	ENSG00000118762	-1.5346424603690347	[570]	[65,29,107]	-8	hSpCas9	negative selection	1731635
88038371	88038394	4	+	26627737	HeLa	viability after 18 days	CGGCAACTCCGAGTCAGAAATGG	PKD2	ENSG00000118762	-0.40750318816600584	[1889]	[342,502,625]	-4	hSpCas9	negative selection	1731636
88043376	88043399	4	+	26627737	HeLa	viability after 18 days	TCTGGCTGGACCGAGGAACCAGG	PKD2	ENSG00000118762	0.004893652307891405	[677]	[282,90,298]	0	hSpCas9	negative selection	1731637
88056217	88056240	4	-	26627737	HeLa	viability after 18 days	CGACCTGAGTGCCAAAGACAAGG	PKD2	ENSG00000118762	0.13670471728404765	[2665]	[826,1270,779]	1	hSpCas9	negative selection	1731638
88065857	88065880	4	+	26627737	HeLa	viability after 18 days	GAGACGACTTGGAGAAAGAGAGG	PKD2	ENSG00000118762	-0.12476354789185606	[239]	[47,46,144]	-1	hSpCas9	negative selection	1731639
88067995	88068018	4	+	26627737	HeLa	viability after 18 days	ATAGCGGACATAGCTCCAGAAGG	PKD2	ENSG00000118762	1.1822310140603953	[167]	[156,109,92]	8	hSpCas9	negative selection	1731640
88008073	88008096	4	+	26627737	HCT116	viability after 6 days	ATGGACGTAGAGTGGCGCCCGGG	PKD2	ENSG00000118762	1.3278162646882299	[578]	[232,225]	7	hSpCas9	negative selection	1813950
88038371	88038394	4	+	26627737	HCT116	viability after 6 days	CGGCAACTCCGAGTCAGAAATGG	PKD2	ENSG00000118762	1.4680447655290079	[1937]	[381,1096]	7	hSpCas9	negative selection	1813951
88043376	88043399	4	+	26627737	HCT116	viability after 6 days	TCTGGCTGGACCGAGGAACCAGG	PKD2	ENSG00000118762	1.5122885963875574	[780]	[230,415]	7	hSpCas9	negative selection	1813952
88056217	88056240	4	-	26627737	HCT116	viability after 6 days	CGACCTGAGTGCCAAAGACAAGG	PKD2	ENSG00000118762	0.004356137534852866	[3825]	[572,619]	0	hSpCas9	negative selection	1813953
88065857	88065880	4	+	26627737	HCT116	viability after 6 days	GAGACGACTTGGAGAAAGAGAGG	PKD2	ENSG00000118762	-2.7509363400953815	[469]	[19,5]	-9	hSpCas9	negative selection	1813954
88067995	88068018	4	+	26627737	HCT116	viability after 6 days	ATAGCGGACATAGCTCCAGAAGG	PKD2	ENSG00000118762	-0.11412072661791162	[266]	[12,52]	0	hSpCas9	negative selection	1813955
88008073	88008096	4	+	26627737	HCT116	viability after 8 days	ATGGACGTAGAGTGGCGCCCGGG	PKD2	ENSG00000118762	-0.6317414874990368	[329]	[80,117,151]	-6	hSpCas9	negative selection	1896265
88038371	88038394	4	+	26627737	HCT116	viability after 8 days	CGGCAACTCCGAGTCAGAAATGG	PKD2	ENSG00000118762	-0.21803573012444621	[1189]	[589,561,539]	-2	hSpCas9	negative selection	1896266
88043376	88043399	4	+	26627737	HCT116	viability after 8 days	TCTGGCTGGACCGAGGAACCAGG	PKD2	ENSG00000118762	0.2348816818277124	[470]	[357,236,321]	2	hSpCas9	negative selection	1896267
88056217	88056240	4	-	26627737	HCT116	viability after 8 days	CGACCTGAGTGCCAAAGACAAGG	PKD2	ENSG00000118762	-0.23287464267967595	[2022]	[1143,906,799]	-3	hSpCas9	negative selection	1896268
88065857	88065880	4	+	26627737	HCT116	viability after 8 days	GAGACGACTTGGAGAAAGAGAGG	PKD2	ENSG00000118762	-0.08593706275385471	[145]	[55,91,78]	-1	hSpCas9	negative selection	1896269
88067995	88068018	4	+	26627737	HCT116	viability after 8 days	ATAGCGGACATAGCTCCAGAAGG	PKD2	ENSG00000118762	0.7403861043215973	[122]	[118,124,95]	7	hSpCas9	negative selection	1896270
88008073	88008096	4	+	26627737	HCT116	viability after 9 days	ATGGACGTAGAGTGGCGCCCGGG	PKD2	ENSG00000118762	-0.6854378332028676	[578]	[194,17]	-5	hSpCas9	negative selection	1978580
88038371	88038394	4	+	26627737	HCT116	viability after 9 days	CGGCAACTCCGAGTCAGAAATGG	PKD2	ENSG00000118762	-0.31999365539635294	[1937]	[437,395]	-2	hSpCas9	negative selection	1978581
88043376	88043399	4	+	26627737	HCT116	viability after 9 days	TCTGGCTGGACCGAGGAACCAGG	PKD2	ENSG00000118762	0.34664021406149387	[780]	[334,209]	2	hSpCas9	negative selection	1978582
88056217	88056240	4	-	26627737	HCT116	viability after 9 days	CGACCTGAGTGCCAAAGACAAGG	PKD2	ENSG00000118762	0.06061643876601819	[3825]	[1332,853]	0	hSpCas9	negative selection	1978583
88065857	88065880	4	+	26627737	HCT116	viability after 9 days	GAGACGACTTGGAGAAAGAGAGG	PKD2	ENSG00000118762	-0.8980851375888075	[469]	[44,84]	-6	hSpCas9	negative selection	1978584
88067995	88068018	4	+	26627737	HCT116	viability after 9 days	ATAGCGGACATAGCTCCAGAAGG	PKD2	ENSG00000118762	1.035719950319149	[266]	[239,71]	7	hSpCas9	negative selection	1978585
88008073	88008096	4	+	26627737	HCT116	viability after 12 days	ATGGACGTAGAGTGGCGCCCGGG	PKD2	ENSG00000118762	-1.8375218039927597	[329]	[43,90,11]	-9	hSpCas9	negative selection	2060895
88038371	88038394	4	+	26627737	HCT116	viability after 12 days	CGGCAACTCCGAGTCAGAAATGG	PKD2	ENSG00000118762	-0.6865355320888313	[1189]	[371,504,292]	-6	hSpCas9	negative selection	2060896
88043376	88043399	4	+	26627737	HCT116	viability after 12 days	TCTGGCTGGACCGAGGAACCAGG	PKD2	ENSG00000118762	0.020050105632542947	[470]	[194,255,306]	0	hSpCas9	negative selection	2060897
88056217	88056240	4	-	26627737	HCT116	viability after 12 days	CGACCTGAGTGCCAAAGACAAGG	PKD2	ENSG00000118762	-0.24940765746096138	[2022]	[1008,852,809]	-3	hSpCas9	negative selection	2060898
88065857	88065880	4	+	26627737	HCT116	viability after 12 days	GAGACGACTTGGAGAAAGAGAGG	PKD2	ENSG00000118762	0.6298805098261427	[145]	[46,180,135]	6	hSpCas9	negative selection	2060899
88067995	88068018	4	+	26627737	HCT116	viability after 12 days	ATAGCGGACATAGCTCCAGAAGG	PKD2	ENSG00000118762	0.5771122088575774	[122]	[154,89,38]	5	hSpCas9	negative selection	2060900
88008073	88008096	4	+	26627737	HCT116	viability after 15 days	ATGGACGTAGAGTGGCGCCCGGG	PKD2	ENSG00000118762	-1.4356427758518988	[329]	[45,69,90]	-8	hSpCas9	negative selection	2143210
88038371	88038394	4	+	26627737	HCT116	viability after 15 days	CGGCAACTCCGAGTCAGAAATGG	PKD2	ENSG00000118762	-0.46465635782909476	[1189]	[746,412,357]	-5	hSpCas9	negative selection	2143211
88043376	88043399	4	+	26627737	HCT116	viability after 15 days	TCTGGCTGGACCGAGGAACCAGG	PKD2	ENSG00000118762	0.5056485011659563	[470]	[447,253,456]	5	hSpCas9	negative selection	2143212
88056217	88056240	4	-	26627737	HCT116	viability after 15 days	CGACCTGAGTGCCAAAGACAAGG	PKD2	ENSG00000118762	-0.08097120081104414	[2022]	[1525,871,950]	-1	hSpCas9	negative selection	2143213
88065857	88065880	4	+	26627737	HCT116	viability after 15 days	GAGACGACTTGGAGAAAGAGAGG	PKD2	ENSG00000118762	0.5535196749335805	[145]	[75,126,159]	5	hSpCas9	negative selection	2143214
88067995	88068018	4	+	26627737	HCT116	viability after 15 days	ATAGCGGACATAGCTCCAGAAGG	PKD2	ENSG00000118762	0.48346593309913355	[122]	[142,87,70]	4	hSpCas9	negative selection	2143215
88008073	88008096	4	+	26627737	HCT116	viability after 18 days	ATGGACGTAGAGTGGCGCCCGGG	PKD2	ENSG00000118762	-0.9018884277704144	[329]	[123,27,108]	-7	hSpCas9	negative selection	2225525
88038371	88038394	4	+	26627737	HCT116	viability after 18 days	CGGCAACTCCGAGTCAGAAATGG	PKD2	ENSG00000118762	-0.20751251012348737	[1189]	[470,523,497]	-2	hSpCas9	negative selection	2225526
88043376	88043399	4	+	26627737	HCT116	viability after 18 days	TCTGGCTGGACCGAGGAACCAGG	PKD2	ENSG00000118762	0.8194835972462496	[470]	[461,398,341]	6	hSpCas9	negative selection	2225527
88056217	88056240	4	-	26627737	HCT116	viability after 18 days	CGACCTGAGTGCCAAAGACAAGG	PKD2	ENSG00000118762	0.09032108593156396	[2022]	[1088,1223,786]	0	hSpCas9	negative selection	2225528
88065857	88065880	4	+	26627737	HCT116	viability after 18 days	GAGACGACTTGGAGAAAGAGAGG	PKD2	ENSG00000118762	0.1261050274138129	[145]	[42,48,143]	1	hSpCas9	negative selection	2225529
88067995	88068018	4	+	26627737	HCT116	viability after 18 days	ATAGCGGACATAGCTCCAGAAGG	PKD2	ENSG00000118762	0.7573885352319433	[122]	[162,53,86]	6	hSpCas9	negative selection	2225530
88007744	88007767	4	-	24336569	HL60	viability	CTGCTGAGGCTGCACGCGACTGG	PKD2	ENSG00000118762	1.1012040313436067	[525]	[2387]	8	hSpCas9	negative selection	2284353
88007749	88007772	4	+	24336569	HL60	viability	CGCGTGCAGCCTCAGCAGCCCGG	PKD2	ENSG00000118762	-1.4952907773096924	[396]	[297]	-8	hSpCas9	negative selection	2284354
88007808	88007831	4	-	24336569	HL60	viability	AGCCAGCCATCAGCCGGCCCGGG	PKD2	ENSG00000118762	0.2059622061250415	[346]	[846]	2	hSpCas9	negative selection	2284355
88007814	88007837	4	-	24336569	HL60	viability	CCGCGCAGCCAGCCATCAGCCGG	PKD2	ENSG00000118762	-0.15319307864179188	[834]	[1588]	-1	hSpCas9	negative selection	2284356
88007820	88007843	4	+	24336569	HL60	viability	GATGGCTGGCTGCGCGGCCGTGG	PKD2	ENSG00000118762	0.9444791666233858	[495]	[2019]	7	hSpCas9	negative selection	2284357
88007859	88007882	4	-	24336569	HL60	viability	GCTGCTCGCAGAGGCCGCCCGGG	PKD2	ENSG00000118762	0.7371784685714218	[581]	[2052]	6	hSpCas9	negative selection	2284358
88007886	88007909	4	-	24336569	HL60	viability	TGCGCTGCATCTCGATCTCCAGG	PKD2	ENSG00000118762	-0.7670828147948823	[804]	[1000]	-6	hSpCas9	negative selection	2284359
88007891	88007914	4	+	24336569	HL60	viability	AGATCGAGATGCAGCGCATCCGG	PKD2	ENSG00000118762	-1.3771128707174098	[339]	[276]	-8	hSpCas9	negative selection	2284360
88007898	88007921	4	+	24336569	HL60	viability	GATGCAGCGCATCCGGCAGGCGG	PKD2	ENSG00000118762	-0.6149476991782968	[1107]	[1530]	-5	hSpCas9	negative selection	2284361
88007955	88007978	4	-	24336569	HL60	viability	ACGACGAGAGCGGAGGAGAAGGG	PKD2	ENSG00000118762	-0.05357470345542681	[998]	[2036]	0	hSpCas9	negative selection	2284362
88007744	88007767	4	-	24336569	KBM7	viability	CTGCTGAGGCTGCACGCGACTGG	PKD2	ENSG00000118762	0.5616158316512515	[390]	[1573]	5	hSpCas9	negative selection	2351530
88007749	88007772	4	+	24336569	KBM7	viability	CGCGTGCAGCCTCAGCAGCCCGG	PKD2	ENSG00000118762	0.9339728810248983	[236]	[1234]	7	hSpCas9	negative selection	2351531
88007808	88007831	4	-	24336569	KBM7	viability	AGCCAGCCATCAGCCGGCCCGGG	PKD2	ENSG00000118762	0.15799358384755996	[555]	[1691]	1	hSpCas9	negative selection	2351532
88007814	88007837	4	-	24336569	KBM7	viability	CCGCGCAGCCAGCCATCAGCCGG	PKD2	ENSG00000118762	0.6736836861938417	[401]	[1748]	6	hSpCas9	negative selection	2351533
88007820	88007843	4	+	24336569	KBM7	viability	GATGGCTGGCTGCGCGGCCGTGG	PKD2	ENSG00000118762	0.5484446088141379	[544]	[2173]	5	hSpCas9	negative selection	2351534
88007859	88007882	4	-	24336569	KBM7	viability	GCTGCTCGCAGAGGCCGCCCGGG	PKD2	ENSG00000118762	0.34855545553803635	[460]	[1600]	3	hSpCas9	negative selection	2351535
88007886	88007909	4	-	24336569	KBM7	viability	TGCGCTGCATCTCGATCTCCAGG	PKD2	ENSG00000118762	0.39170858881400983	[599]	[2146]	3	hSpCas9	negative selection	2351536
88007891	88007914	4	+	24336569	KBM7	viability	AGATCGAGATGCAGCGCATCCGG	PKD2	ENSG00000118762	0.9048026948801937	[74]	[382]	7	hSpCas9	negative selection	2351537
88007898	88007921	4	+	24336569	KBM7	viability	GATGCAGCGCATCCGGCAGGCGG	PKD2	ENSG00000118762	-0.553914702205138	[956]	[1777]	-4	hSpCas9	negative selection	2351538
88007955	88007978	4	-	24336569	KBM7	viability	ACGACGAGAGCGGAGGAGAAGGG	PKD2	ENSG00000118762	-0.14489145835817174	[935]	[2308]	-1	hSpCas9	negative selection	2351539
88033382	88033405	4	+	25494202	A375	resistance to PLX-4720 (puromycin)	GTGCCACTGCACTCCAGCCTTGG	PKD2	ENSG00000118762	-0.4511660430985071	[55,91]	[10,11]	-2	dCas9-VP64	positive selection	2390570
88074246	88074269	4	+	25494202	A375	resistance to PLX-4720 (puromycin)	CTCAGGTGATCCTTCCACCTCAG	PKD2	ENSG00000118762	-1.437181231551541	[165,262]	[21,11]	-8	dCas9-VP64	positive selection	2441646
88047294	88047317	4	+	25494202	A375	resistance to PLX-4720 (puromycin)	TGCCTGTAATCCCAGCACTTGGG	PKD2	ENSG00000118762	-1.262579619046977	[170,274]	[19,19]	-7	dCas9-VP64	positive selection	2446349
88033382	88033405	4	+	25494202	A375	resistance to PLX-4720 (zeocin)	GTGCCACTGCACTCCAGCCTTGG	PKD2	ENSG00000118762	-0.10831419915270625	[89,129]	[31,33]	-1	dCas9-VP64	positive selection	2485825
88074246	88074269	4	+	25494202	A375	resistance to PLX-4720 (zeocin)	CTCAGGTGATCCTTCCACCTCAG	PKD2	ENSG00000118762	0.43444246644375656	[171,135]	[90,46]	3	dCas9-VP64	positive selection	2536901
88047294	88047317	4	+	25494202	A375	resistance to PLX-4720 (zeocin)	TGCCTGTAATCCCAGCACTTGGG	PKD2	ENSG00000118762	0.31922581039074327	[700,765]	[259,334]	2	dCas9-VP64	positive selection	2541604
88019543	88019566	4	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	ACAAGACTATGAGAAAAAGGAGG	PKD2	ENSG00000118762	0.46887252637714305	[3,3]	[2,6]	8	hSpCas9	positive selection	3011551
88007907	88007930	4	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCATCCGGCAGGCGGCCGCGCGG	PKD2	ENSG00000118762	0.12918604701109732	[3,3]	[3,3]	2	hSpCas9	positive selection	3011552
88046650	88046673	4	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GTTGAATTCCCAGCAACAGGTGG	PKD2	ENSG00000118762	0.3601002290765594	[2,3]	[3,3]	7	hSpCas9	positive selection	3011553
88038406	88038429	4	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TTTCATCTCTCAAGTCCTGGGGG	PKD2	ENSG00000118762	-0.30425022349915487	[3,3]	[0,3]	-4	hSpCas9	positive selection	3011554
88019543	88019566	4	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	ACAAGACTATGAGAAAAAGGAGG	PKD2	ENSG00000118762	-0.7356325465759357	[3,3]	[2,0]	-8	hSpCas9	positive selection	3079409
88007907	88007930	4	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCATCCGGCAGGCGGCCGCGCGG	PKD2	ENSG00000118762	0.039651500701408465	[3,3]	[3,2]	0	hSpCas9	positive selection	3079410
88046650	88046673	4	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GTTGAATTCCCAGCAACAGGTGG	PKD2	ENSG00000118762	-0.11192186291365386	[2,2]	[3,0]	-2	hSpCas9	positive selection	3079411
88038406	88038429	4	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TTTCATCTCTCAAGTCCTGGGGG	PKD2	ENSG00000118762	0.2966594910164948	[3,3]	[2,3]	5	hSpCas9	positive selection	3079412
88065370	88065393		+	24336571	A375	resistance to PLX after 7 days	ATAGGGCTACCATAAAGCTTTGG	PKD2	ENSG00000118762	0.005520375350244855	[16,17]	[16,17]	0	hSpCas9	positive selection	3135820
88043358	88043381		+	24336571	A375	resistance to PLX after 7 days	CTAGCCTCAAGAAAAATGTCTGG	PKD2	ENSG00000118762	0.4090840336926296	[6,4]	[6,8]	8	hSpCas9	positive selection	3135821
88065473	88065496		+	24336571	A375	resistance to PLX after 7 days	GAACTTCGACAAGATCTCAAAGG	PKD2	ENSG00000118762	0.19232959661199844	[4,4]	[6,4]	6	hSpCas9	positive selection	3135822
88065370	88065393		+	24336571	A375	resistance to PLX after 14 days	ATAGGGCTACCATAAAGCTTTGG	PKD2	ENSG00000118762	-0.3994110771744034	[16,15]	[6,3]	-5	hSpCas9	positive selection	3193613
88043358	88043381		+	24336571	A375	resistance to PLX after 14 days	CTAGCCTCAAGAAAAATGTCTGG	PKD2	ENSG00000118762	3.4363181141664647	[2,7]	[31,29]	9	hSpCas9	positive selection	3193614
88065473	88065496		+	24336571	A375	resistance to PLX after 14 days	GAACTTCGACAAGATCTCAAAGG	PKD2	ENSG00000118762	0.5459045095987117	[5,3]	[2,2]	5	hSpCas9	positive selection	3193615
88065370	88065393		+	24336571	A375	viability after 7 days	ATAGGGCTACCATAAAGCTTTGG	PKD2	ENSG00000118762	-0.04879412874634237	[18]	[16,17]	0	hSpCas9	negative selection	3251406
88043358	88043381		+	24336571	A375	viability after 7 days	CTAGCCTCAAGAAAAATGTCTGG	PKD2	ENSG00000118762	0.0357137461193231	[5]	[6,4]	0	hSpCas9	negative selection	3251407
88065473	88065496		+	24336571	A375	viability after 7 days	GAACTTCGACAAGATCTCAAAGG	PKD2	ENSG00000118762	-1.1646447855523236	[12]	[4,4]	-9	hSpCas9	negative selection	3251408
88065370	88065393		+	24336571	A375	viability after 14 days	ATAGGGCTACCATAAAGCTTTGG	PKD2	ENSG00000118762	-0.10960207855680998	[18]	[16,15]	-1	hSpCas9	negative selection	3309199
88043358	88043381		+	24336571	A375	viability after 14 days	CTAGCCTCAAGAAAAATGTCTGG	PKD2	ENSG00000118762	-0.0061870252993083685	[5]	[2,7]	0	hSpCas9	negative selection	3309200
88065473	88065496		+	24336571	A375	viability after 14 days	GAACTTCGACAAGATCTCAAAGG	PKD2	ENSG00000118762	-1.20312491040678	[12]	[5,3]	-9	hSpCas9	negative selection	3309201
88065796	88065819	4	+	27383988	293T	resistance to West Nile virus (flavivirus)	TTCACAAAGTACGACCAAGATGG	PKD2	ENSG00000118762	-0.9618423090163265	[297,297]	[0,0]	-6	hSpCas9	positive selection	3386022
88043279	88043302	4	+	27383988	293T	resistance to West Nile virus (flavivirus)	GGAATCATTGCAACTTATAGTGG	PKD2	ENSG00000118762	0.9905396707509337	[76,76]	[0,0]	4	hSpCas9	positive selection	3386023
88043272	88043295	4	-	27383988	293T	resistance to West Nile virus (flavivirus)	AAGTTGCAATGATTCCCCAGTGG	PKD2	ENSG00000118762	1.3504356158373165	[59,59]	[0,0]	6	hSpCas9	positive selection	3386024
88019543	88019566	4	-	26780180	HT29	viability (Avana library 4 designs)	ACAAGACTATGAGAAAAAGGAGG	PKD2	ENSG00000118762	0.700933947473695	[]	[]	2	hSpCas9	negative selection	3449640
88007906	88007929	4	+	26780180	HT29	viability (Avana library 4 designs)	GCATCCGGCAGGCGGCCGCGCGG	PKD2	ENSG00000118762	0.667148442229174	[]	[]	2	hSpCas9	negative selection	3449641
88046649	88046672	4	+	26780180	HT29	viability (Avana library 4 designs)	GTTGAATTCCCAGCAACAGGTGG	PKD2	ENSG00000118762	1.48497456909514	[]	[]	6	hSpCas9	negative selection	3449642
88038406	88038429	4	-	26780180	HT29	viability (Avana library 4 designs)	TTTCATCTCTCAAGTCCTGGGGG	PKD2	ENSG00000118762	0.956555063522555	[]	[]	3	hSpCas9	negative selection	3449643
88007906	88007929	4	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCATCCGGCAGGCGGCCGCGCGG	PKD2	ENSG00000118762	3.49769483106084	[]	[]	5	hSpCas9	negative selection	3544498
88019543	88019566	4	-	26780180	A375	viability (Avana lentiCRISPRv2)	ACAAGACTATGAGAAAAAGGAGG	PKD2	ENSG00000118762	-7.73684233227844	[]	[]	-7	hSpCas9	negative selection	3544499
88046649	88046672	4	+	26780180	A375	viability (Avana lentiCRISPRv2)	GTTGAATTCCCAGCAACAGGTGG	PKD2	ENSG00000118762	-3.55906304671953	[]	[]	-4	hSpCas9	negative selection	3544500
88038406	88038429	4	-	26780180	A375	viability (Avana lentiCRISPRv2)	TTTCATCTCTCAAGTCCTGGGGG	PKD2	ENSG00000118762	-2.71223713239593	[]	[]	-3	hSpCas9	negative selection	3544501
88043317	88043340	4	+	26780180	A375	viability (Avana lentiCRISPRv2)	GGATTTGTCAAGAACAAGAGAGG	PKD2	ENSG00000118762	-2.73251992392872	[]	[]	-3	hSpCas9	negative selection	3544502
88007751	88007774	4	+	26780180	A375	viability (Avana lentiCRISPRv2)	CGTGCAGCCTCAGCAGCCCGGGG	PKD2	ENSG00000118762	3.75143021567238	[]	[]	6	hSpCas9	negative selection	3544503
88007906	88007929	4	+	26780180	A375	viability (Avana lentiGuide)	GCATCCGGCAGGCGGCCGCGCGG	PKD2	ENSG00000118762	1.83104885788712	[]	[]	2	hSpCas9	negative selection	3653157
88019543	88019566	4	-	26780180	A375	viability (Avana lentiGuide)	ACAAGACTATGAGAAAAAGGAGG	PKD2	ENSG00000118762	-4.33802803017071	[]	[]	-7	hSpCas9	negative selection	3653158
88046649	88046672	4	+	26780180	A375	viability (Avana lentiGuide)	GTTGAATTCCCAGCAACAGGTGG	PKD2	ENSG00000118762	0.730491524218517	[]	[]	0	hSpCas9	negative selection	3653159
88038406	88038429	4	-	26780180	A375	viability (Avana lentiGuide)	TTTCATCTCTCAAGTCCTGGGGG	PKD2	ENSG00000118762	-3.3767016842692	[]	[]	-6	hSpCas9	negative selection	3653160
88043317	88043340	4	+	26780180	A375	viability (Avana lentiGuide)	GGATTTGTCAAGAACAAGAGAGG	PKD2	ENSG00000118762	-7.6246639915811	[]	[]	-9	hSpCas9	negative selection	3653161
88007751	88007774	4	+	26780180	A375	viability (Avana lentiGuide)	CGTGCAGCCTCAGCAGCCCGGGG	PKD2	ENSG00000118762	5.43851088636161	[]	[]	5	hSpCas9	negative selection	3653162
88007906	88007929	4	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCATCCGGCAGGCGGCCGCGCGG	PKD2	ENSG00000118762	0.2354825623258574	[4]	[5,5]	6	hSpCas9	positive selection	3761816
88019543	88019566	4	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ACAAGACTATGAGAAAAAGGAGG	PKD2	ENSG00000118762	-0.9741115368174389	[5]	[2,2]	-8	hSpCas9	positive selection	3761817
88046649	88046672	4	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GTTGAATTCCCAGCAACAGGTGG	PKD2	ENSG00000118762	-0.46583572505242976	[4]	[2,2]	-6	hSpCas9	positive selection	3761818
88038406	88038429	4	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TTTCATCTCTCAAGTCCTGGGGG	PKD2	ENSG00000118762	-0.02163249947349828	[5]	[4,4]	0	hSpCas9	positive selection	3761819
88043317	88043340	4	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGATTTGTCAAGAACAAGAGAGG	PKD2	ENSG00000118762	-0.19961799343206132	[4]	[4,3]	-3	hSpCas9	positive selection	3761820
88007751	88007774	4	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CGTGCAGCCTCAGCAGCCCGGGG	PKD2	ENSG00000118762	0.18494830792418235	[5]	[5,5]	5	hSpCas9	positive selection	3761821
88007906	88007929	4	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCATCCGGCAGGCGGCCGCGCGG	PKD2	ENSG00000118762	-0.22578522792250333	[6]	[4,3]	-3	hSpCas9	positive selection	3870423
88019543	88019566	4	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ACAAGACTATGAGAAAAAGGAGG	PKD2	ENSG00000118762	-0.1022914373046751	[5]	[4,3]	-1	hSpCas9	positive selection	3870424
88046649	88046672	4	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GTTGAATTCCCAGCAACAGGTGG	PKD2	ENSG00000118762	-0.0886289669261533	[4]	[5,1]	-1	hSpCas9	positive selection	3870425
88038406	88038429	4	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TTTCATCTCTCAAGTCCTGGGGG	PKD2	ENSG00000118762	-0.05191561154718046	[5]	[4,3]	0	hSpCas9	positive selection	3870426
88043317	88043340	4	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGATTTGTCAAGAACAAGAGAGG	PKD2	ENSG00000118762	0.036149259077101176	[5]	[4,4]	0	hSpCas9	positive selection	3870427
88007751	88007774	4	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CGTGCAGCCTCAGCAGCCCGGGG	PKD2	ENSG00000118762	-0.209895479142725	[5]	[4,3]	-3	hSpCas9	positive selection	3870428
88043272	88043295	4	-	26780180	A375	viability	AAGTTGCAATGATTCCCCAGTGG	PKD2	ENSG00000118762	0.60433264694698	[]	[]	2	hSpCas9	negative selection	3981238
88065370	88065393	4	+	26780180	A375	viability	ATAGGGCTACCATAAAGCTTTGG	PKD2	ENSG00000118762	1.25879280655336	[]	[]	6	hSpCas9	negative selection	3981239
88065473	88065496	4	+	26780180	A375	viability	GAACTTCGACAAGATCTCAAAGG	PKD2	ENSG00000118762	0.399625090797073	[]	[]	0	hSpCas9	negative selection	3981240
88043279	88043302	4	+	26780180	A375	viability	GGAATCATTGCAACTTATAGTGG	PKD2	ENSG00000118762	1.18552643743697	[]	[]	6	hSpCas9	negative selection	3981241
88065846	88065869	4	+	26780180	A375	viability	TCAGCAGATGAGAGACGACTTGG	PKD2	ENSG00000118762	1.02754643945116	[]	[]	5	hSpCas9	negative selection	3981242
88065796	88065819	4	+	26780180	A375	viability	TTCACAAAGTACGACCAAGATGG	PKD2	ENSG00000118762	0.679594854306916	[]	[]	2	hSpCas9	negative selection	3981243
88043272	88043295	4	-	26780180	HT29	viability (GeCKOv2 library)	AAGTTGCAATGATTCCCCAGTGG	PKD2	ENSG00000118762	0.920917960038808	[]	[]	4	hSpCas9	negative selection	4089204
88065370	88065393	4	+	26780180	HT29	viability (GeCKOv2 library)	ATAGGGCTACCATAAAGCTTTGG	PKD2	ENSG00000118762	0.916795695478231	[]	[]	4	hSpCas9	negative selection	4089205
88065473	88065496	4	+	26780180	HT29	viability (GeCKOv2 library)	GAACTTCGACAAGATCTCAAAGG	PKD2	ENSG00000118762	0.193294176156096	[]	[]	0	hSpCas9	negative selection	4089206
88043279	88043302	4	+	26780180	HT29	viability (GeCKOv2 library)	GGAATCATTGCAACTTATAGTGG	PKD2	ENSG00000118762	0.89756893506142	[]	[]	4	hSpCas9	negative selection	4089207
88065846	88065869	4	+	26780180	HT29	viability (GeCKOv2 library)	TCAGCAGATGAGAGACGACTTGG	PKD2	ENSG00000118762	0.69748818860222	[]	[]	2	hSpCas9	negative selection	4089208
88065796	88065819	4	+	26780180	HT29	viability (GeCKOv2 library)	TTCACAAAGTACGACCAAGATGG	PKD2	ENSG00000118762	0.246771967161912	[]	[]	0	hSpCas9	negative selection	4089209
88065370	88065393	4	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	ATAGGGCTACCATAAAGCTTTGG	PKD2	ENSG00000118762	-0.143804381336678	[4]	[2,2]	-3	hSpCas9	positive selection	4160798
88043358	88043381	4	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CTAGCCTCAAGAAAAATGTCTGG	PKD2	ENSG00000118762	0.4461757186591295	[2]	[0,4]	8	hSpCas9	positive selection	4160799
88065473	88065496	4	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GAACTTCGACAAGATCTCAAAGG	PKD2	ENSG00000118762	0.116160716863773	[2]	[1,1]	3	hSpCas9	positive selection	4160800
88065370	88065393	4	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	ATAGGGCTACCATAAAGCTTTGG	PKD2	ENSG00000118762	-0.6411506435523467	[3]	[0,1,0,0]	-8	hSpCas9	positive selection	4224820
88043358	88043381	4	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CTAGCCTCAAGAAAAATGTCTGG	PKD2	ENSG00000118762	-0.02917899386298295	[1]	[0,0,0,0]	0	hSpCas9	positive selection	4224821
88065473	88065496	4	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GAACTTCGACAAGATCTCAAAGG	PKD2	ENSG00000118762	1.2829984210244492	[3]	[3,4,1,4]	9	hSpCas9	positive selection	4224822
88065370	88065393	4	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ATAGGGCTACCATAAAGCTTTGG	PKD2	ENSG00000118762	0.411672886142749	[4]	[4,4]	8	hSpCas9	positive selection	4290447
88065473	88065496	4	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GAACTTCGACAAGATCTCAAAGG	PKD2	ENSG00000118762	0.3133567131306678	[0]	[1,0]	6	hSpCas9	positive selection	4290448
88065846	88065869	4	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TCAGCAGATGAGAGACGACTTGG	PKD2	ENSG00000118762	-0.24460338482062266	[2]	[1,0]	-5	hSpCas9	positive selection	4290449
88065796	88065819	4	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TTCACAAAGTACGACCAAGATGG	PKD2	ENSG00000118762	0.33975516732668126	[4]	[4,3]	7	hSpCas9	positive selection	4354699
88043279	88043302	4	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GGAATCATTGCAACTTATAGTGG	PKD2	ENSG00000118762	-0.32025835534360825	[1]	[1,0]	-6	hSpCas9	positive selection	4354700
88043272	88043295	4	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AAGTTGCAATGATTCCCCAGTGG	PKD2	ENSG00000118762	-0.09163256945744752	[2]	[1,1]	-2	hSpCas9	positive selection	4354701
88007892	88007914	4	+	27760321	OCIAML3	viability	GATCGAGATGCAGCGCATCCGG	PKD2	ENSG00000118762	-0.03590406947441138	[377,340]	[240,316]	0	hSpCas9	negative selection	4428088
88007990	88008012	4	+	27760321	OCIAML3	viability	CGTGGAGCCGCGATAACCCCGG	PKD2	ENSG00000118762	0.28713905159225256	[409,366]	[302,457]	3	hSpCas9	negative selection	4428089
88008074	88008096	4	+	27760321	OCIAML3	viability	TGGACGTAGAGTGGCGCCCGGG	PKD2	ENSG00000118762	0.3432577426253509	[633,554]	[532,660]	4	hSpCas9	negative selection	4428090
88036216	88036238	4	-	27760321	OCIAML3	viability	TCATCATGCCGTAGGTCACTGG	PKD2	ENSG00000118762	0.006195093390486683	[623,515]	[390,516]	0	hSpCas9	negative selection	4428091
88038352	88038374	4	+	27760321	OCIAML3	viability	GTTAGGGGTTCCACGAATACGG	PKD2	ENSG00000118762	-0.4021672726261747	[205,187]	[96,141]	-4	hSpCas9	negative selection	4428092
88007892	88007914	4	+	27760321	OCIAML2	viability	GATCGAGATGCAGCGCATCCGG	PKD2	ENSG00000118762	0.029847515366252575	[377,340]	[205,415]	0	hSpCas9	negative selection	4511551
88007990	88008012	4	+	27760321	OCIAML2	viability	CGTGGAGCCGCGATAACCCCGG	PKD2	ENSG00000118762	0.1732697826086674	[409,366]	[299,424]	2	hSpCas9	negative selection	4511552
88008074	88008096	4	+	27760321	OCIAML2	viability	TGGACGTAGAGTGGCGCCCGGG	PKD2	ENSG00000118762	0.09436741958440731	[633,554]	[485,546]	1	hSpCas9	negative selection	4511553
88036216	88036238	4	-	27760321	OCIAML2	viability	TCATCATGCCGTAGGTCACTGG	PKD2	ENSG00000118762	-0.1954419272307917	[623,515]	[355,459]	-2	hSpCas9	negative selection	4511554
88038352	88038374	4	+	27760321	OCIAML2	viability	GTTAGGGGTTCCACGAATACGG	PKD2	ENSG00000118762	-0.20292819794357486	[205,187]	[143,130]	-3	hSpCas9	negative selection	4511555
88007892	88007914	4	+	27760321	MV411	viability	GATCGAGATGCAGCGCATCCGG	PKD2	ENSG00000118762	0.36440211075335793	[377,340]	[444,94]	2	hSpCas9	negative selection	4595014
88007990	88008012	4	+	27760321	MV411	viability	CGTGGAGCCGCGATAACCCCGG	PKD2	ENSG00000118762	0.16034060493936816	[409,366]	[222,380]	1	hSpCas9	negative selection	4595015
88008074	88008096	4	+	27760321	MV411	viability	TGGACGTAGAGTGGCGCCCGGG	PKD2	ENSG00000118762	0.30299061936372085	[633,554]	[655,222]	2	hSpCas9	negative selection	4595016
88036216	88036238	4	-	27760321	MV411	viability	TCATCATGCCGTAGGTCACTGG	PKD2	ENSG00000118762	0.3650547701486235	[623,515]	[325,716]	2	hSpCas9	negative selection	4595017
88038352	88038374	4	+	27760321	MV411	viability	GTTAGGGGTTCCACGAATACGG	PKD2	ENSG00000118762	-1.8290928901512442	[205,187]	[0,89]	-8	hSpCas9	negative selection	4595018
88007892	88007914	4	+	27760321	HL60	viability	GATCGAGATGCAGCGCATCCGG	PKD2	ENSG00000118762	0.16661837821373976	[377,340]	[438,212]	2	hSpCas9	negative selection	4678477
88007990	88008012	4	+	27760321	HL60	viability	CGTGGAGCCGCGATAACCCCGG	PKD2	ENSG00000118762	-0.46691316807123384	[409,366]	[239,217]	-5	hSpCas9	negative selection	4678478
88008074	88008096	4	+	27760321	HL60	viability	TGGACGTAGAGTGGCGCCCGGG	PKD2	ENSG00000118762	0.44509135669119493	[633,554]	[765,546]	5	hSpCas9	negative selection	4678479
88036216	88036238	4	-	27760321	HL60	viability	TCATCATGCCGTAGGTCACTGG	PKD2	ENSG00000118762	-0.6297084338122123	[623,515]	[235,366]	-6	hSpCas9	negative selection	4678480
88038352	88038374	4	+	27760321	HL60	viability	GTTAGGGGTTCCACGAATACGG	PKD2	ENSG00000118762	-0.3423602596167048	[205,187]	[105,148]	-4	hSpCas9	negative selection	4678481
88007892	88007914	4	+	27760321	HT1080	viability	GATCGAGATGCAGCGCATCCGG	PKD2	ENSG00000118762	0.09307025322365894	[340,265]	[106,152]	0	hSpCas9	negative selection	4761940
88007990	88008012	4	+	27760321	HT1080	viability	CGTGGAGCCGCGATAACCCCGG	PKD2	ENSG00000118762	0.01995275016297618	[366,286]	[91,175]	0	hSpCas9	negative selection	4761941
88008074	88008096	4	+	27760321	HT1080	viability	TGGACGTAGAGTGGCGCCCGGG	PKD2	ENSG00000118762	-0.6162826014927403	[554,432]	[188,61]	-3	hSpCas9	negative selection	4761942
88036216	88036238	4	-	27760321	HT1080	viability	TCATCATGCCGTAGGTCACTGG	PKD2	ENSG00000118762	1.0648374536036471	[515,402]	[423,337]	6	hSpCas9	negative selection	4761943
88038352	88038374	4	+	27760321	HT1080	viability	GTTAGGGGTTCCACGAATACGG	PKD2	ENSG00000118762	0.5639039341741956	[187,146]	[143,48]	3	hSpCas9	negative selection	4761944
88007892	88007914	4	+	27760321	HT29	viability after 7 days	GATCGAGATGCAGCGCATCCGG	PKD2	ENSG00000118762	-0.26017854329403467	[340,265]	[314,352,307]	-4	hSpCas9	negative selection	4845403
88007990	88008012	4	+	27760321	HT29	viability after 7 days	CGTGGAGCCGCGATAACCCCGG	PKD2	ENSG00000118762	-0.11451163304334125	[366,286]	[577,267,346]	-2	hSpCas9	negative selection	4845404
88008074	88008096	4	+	27760321	HT29	viability after 7 days	TGGACGTAGAGTGGCGCCCGGG	PKD2	ENSG00000118762	0.29936344074279947	[554,432]	[1068,450,861]	4	hSpCas9	negative selection	4845405
88036216	88036238	4	-	27760321	HT29	viability after 7 days	TCATCATGCCGTAGGTCACTGG	PKD2	ENSG00000118762	0.18156096328841292	[515,402]	[844,769,426]	2	hSpCas9	negative selection	4845406
88038352	88038374	4	+	27760321	HT29	viability after 7 days	GTTAGGGGTTCCACGAATACGG	PKD2	ENSG00000118762	0.010778589323967802	[187,146]	[295,277,91]	0	hSpCas9	negative selection	4845407
88007892	88007914	4	+	27760321	HT29	viability after 25 days	GATCGAGATGCAGCGCATCCGG	PKD2	ENSG00000118762	0.25956313766185174	[340,265]	[237,517,509]	2	hSpCas9	negative selection	4928866
88007990	88008012	4	+	27760321	HT29	viability after 25 days	CGTGGAGCCGCGATAACCCCGG	PKD2	ENSG00000118762	0.0008571453893287118	[366,286]	[259,343,541]	0	hSpCas9	negative selection	4928867
88008074	88008096	4	+	27760321	HT29	viability after 25 days	TGGACGTAGAGTGGCGCCCGGG	PKD2	ENSG00000118762	0.36505379190690973	[554,432]	[593,742,865]	4	hSpCas9	negative selection	4928868
88036216	88036238	4	-	27760321	HT29	viability after 25 days	TCATCATGCCGTAGGTCACTGG	PKD2	ENSG00000118762	-0.10518005902453756	[515,402]	[366,560,549]	-1	hSpCas9	negative selection	4928869
88038352	88038374	4	+	27760321	HT29	viability after 25 days	GTTAGGGGTTCCACGAATACGG	PKD2	ENSG00000118762	-0.019285641007695142	[187,146]	[120,352,85]	0	hSpCas9	negative selection	4928870
88007892	88007914	4	+	27760321	HT29	viability after 22 days	GATCGAGATGCAGCGCATCCGG	PKD2	ENSG00000118762	0.028725908805695394	[340,265]	[270,556,246]	0	hSpCas9	negative selection	5012329
88007990	88008012	4	+	27760321	HT29	viability after 22 days	CGTGGAGCCGCGATAACCCCGG	PKD2	ENSG00000118762	-0.20608824043239274	[366,286]	[175,308,503]	-2	hSpCas9	negative selection	5012330
88008074	88008096	4	+	27760321	HT29	viability after 22 days	TGGACGTAGAGTGGCGCCCGGG	PKD2	ENSG00000118762	0.14798887102866104	[554,432]	[675,389,832]	1	hSpCas9	negative selection	5012331
88036216	88036238	4	-	27760321	HT29	viability after 22 days	TCATCATGCCGTAGGTCACTGG	PKD2	ENSG00000118762	0.23695579277665274	[515,402]	[683,625,565]	2	hSpCas9	negative selection	5012332
88038352	88038374	4	+	27760321	HT29	viability after 22 days	GTTAGGGGTTCCACGAATACGG	PKD2	ENSG00000118762	0.034875495527685096	[187,146]	[135,353,105]	0	hSpCas9	negative selection	5012333
88007892	88007914	4	+	27760321	HT29	viability after 19 days	GATCGAGATGCAGCGCATCCGG	PKD2	ENSG00000118762	0.2387339693281878	[340,265]	[351,584,289]	2	hSpCas9	negative selection	5095792
88007990	88008012	4	+	27760321	HT29	viability after 19 days	CGTGGAGCCGCGATAACCCCGG	PKD2	ENSG00000118762	0.4222812017723778	[366,286]	[309,583,585]	4	hSpCas9	negative selection	5095793
88008074	88008096	4	+	27760321	HT29	viability after 19 days	TGGACGTAGAGTGGCGCCCGGG	PKD2	ENSG00000118762	0.296856674370056	[554,432]	[1056,699,374]	3	hSpCas9	negative selection	5095794
88036216	88036238	4	-	27760321	HT29	viability after 19 days	TCATCATGCCGTAGGTCACTGG	PKD2	ENSG00000118762	-0.11566991280171704	[515,402]	[598,442,426]	-1	hSpCas9	negative selection	5095795
88038352	88038374	4	+	27760321	HT29	viability after 19 days	GTTAGGGGTTCCACGAATACGG	PKD2	ENSG00000118762	0.46983015206752254	[187,146]	[133,299,344]	4	hSpCas9	negative selection	5095796
88007892	88007914	4	+	27760321	HT29	viability after 16 days	GATCGAGATGCAGCGCATCCGG	PKD2	ENSG00000118762	0.1936691497127917	[340,265]	[420,426,318]	2	hSpCas9	negative selection	5179255
88007990	88008012	4	+	27760321	HT29	viability after 16 days	CGTGGAGCCGCGATAACCCCGG	PKD2	ENSG00000118762	0.5882970509165715	[366,286]	[312,390,927]	6	hSpCas9	negative selection	5179256
88008074	88008096	4	+	27760321	HT29	viability after 16 days	TGGACGTAGAGTGGCGCCCGGG	PKD2	ENSG00000118762	0.2715858173100167	[554,432]	[1224,362,473]	3	hSpCas9	negative selection	5179257
88036216	88036238	4	-	27760321	HT29	viability after 16 days	TCATCATGCCGTAGGTCACTGG	PKD2	ENSG00000118762	-0.08512426866808348	[515,402]	[594,534,332]	-1	hSpCas9	negative selection	5179258
88038352	88038374	4	+	27760321	HT29	viability after 16 days	GTTAGGGGTTCCACGAATACGG	PKD2	ENSG00000118762	-0.4297874992650248	[187,146]	[81,176,151]	-4	hSpCas9	negative selection	5179259
88007892	88007914	4	+	27760321	HT29	viability after 13 days	GATCGAGATGCAGCGCATCCGG	PKD2	ENSG00000118762	0.09673395631012868	[340,265]	[433,347,348]	1	hSpCas9	negative selection	5262718
88007990	88008012	4	+	27760321	HT29	viability after 13 days	CGTGGAGCCGCGATAACCCCGG	PKD2	ENSG00000118762	-0.05349103809653441	[366,286]	[341,290,457]	0	hSpCas9	negative selection	5262719
88008074	88008096	4	+	27760321	HT29	viability after 13 days	TGGACGTAGAGTGGCGCCCGGG	PKD2	ENSG00000118762	0.34393144977606843	[554,432]	[922,522,734]	4	hSpCas9	negative selection	5262720
88036216	88036238	4	-	27760321	HT29	viability after 13 days	TCATCATGCCGTAGGTCACTGG	PKD2	ENSG00000118762	0.45693012196003496	[515,402]	[896,724,581]	6	hSpCas9	negative selection	5262721
88038352	88038374	4	+	27760321	HT29	viability after 13 days	GTTAGGGGTTCCACGAATACGG	PKD2	ENSG00000118762	-0.04229117439273633	[187,146]	[211,214,141]	0	hSpCas9	negative selection	5262722
88007892	88007914	4	+	27760321	HT29	viability after 10 days	GATCGAGATGCAGCGCATCCGG	PKD2	ENSG00000118762	-0.09342938312737634	[340,265]	[314,584,175]	-1	hSpCas9	negative selection	5346181
88007990	88008012	4	+	27760321	HT29	viability after 10 days	CGTGGAGCCGCGATAACCCCGG	PKD2	ENSG00000118762	-0.20650476207630616	[366,286]	[292,369,397]	-3	hSpCas9	negative selection	5346182
88008074	88008096	4	+	27760321	HT29	viability after 10 days	TGGACGTAGAGTGGCGCCCGGG	PKD2	ENSG00000118762	0.13556450089102917	[554,432]	[838,494,692]	1	hSpCas9	negative selection	5346183
88036216	88036238	4	-	27760321	HT29	viability after 10 days	TCATCATGCCGTAGGTCACTGG	PKD2	ENSG00000118762	-0.027218541278134667	[515,402]	[598,547,541]	0	hSpCas9	negative selection	5346184
88038352	88038374	4	+	27760321	HT29	viability after 10 days	GTTAGGGGTTCCACGAATACGG	PKD2	ENSG00000118762	-0.3297750014386207	[187,146]	[277,131,89]	-4	hSpCas9	negative selection	5346185
88007892	88007914	4	+	27760321	MOLM13	viability	GATCGAGATGCAGCGCATCCGG	PKD2	ENSG00000118762	0.03910414314946217	[377,340]	[191,221]	0	hSpCas9	negative selection	5429644
88007990	88008012	4	+	27760321	MOLM13	viability	CGTGGAGCCGCGATAACCCCGG	PKD2	ENSG00000118762	1.4269313829671633	[409,366]	[983,251]	8	hSpCas9	negative selection	5429645
88008074	88008096	4	+	27760321	MOLM13	viability	TGGACGTAGAGTGGCGCCCGGG	PKD2	ENSG00000118762	1.1342824892335284	[633,554]	[913,581]	7	hSpCas9	negative selection	5429646
88036216	88036238	4	-	27760321	MOLM13	viability	TCATCATGCCGTAGGTCACTGG	PKD2	ENSG00000118762	0.061109000612458886	[623,515]	[407,270]	0	hSpCas9	negative selection	5429647
88038352	88038374	4	+	27760321	MOLM13	viability	GTTAGGGGTTCCACGAATACGG	PKD2	ENSG00000118762	-1.0716642118423703	[205,187]	[0,96]	-6	hSpCas9	negative selection	5429648
88007675	88007698	4	+	27661255	K562	viability	GAGGCGCACAGCGCCGAGCGCGG	PKD2	ENSG00000118762	-0.3762612371784543	[542,455]	[343,277]	-7	dCas9-KRAB	negative selection	5502125
88007707	88007730	4	-	27661255	K562	viability	GTCACTGGCGTCCGGCGCGCGGG	PKD2	ENSG00000118762	0.3532963748929311	[519,696]	[621,613]	9	dCas9-KRAB	negative selection	5502126
88007722	88007745	4	-	27661255	K562	viability	GAGTTCACCATCGCGGTCACTGG	PKD2	ENSG00000118762	0.08982301153667249	[890,1036]	[860,779]	3	dCas9-KRAB	negative selection	5502127
88007729	88007752	4	-	27661255	K562	viability	GCGACTGGAGTTCACCATCGCGG	PKD2	ENSG00000118762	0.162674936252592	[430,462]	[423,377]	5	dCas9-KRAB	negative selection	5502128
88065370	88065393	4	+	27260156	BXPC3	viability	ATAGGGCTACCATAAAGCTTTGG	PKD2	ENSG00000118762	-0.21897452513738602	[1202]	[948,925,1217,1271]	-5	hSpCas9	negative selection	5562907
88065473	88065496	4	+	27260156	BXPC3	viability	GAACTTCGACAAGATCTCAAAGG	PKD2	ENSG00000118762	-0.14618325552127187	[34]	[8,61,35,24]	-3	hSpCas9	negative selection	5562908
88065846	88065869	4	+	27260156	BXPC3	viability	TCAGCAGATGAGAGACGACTTGG	PKD2	ENSG00000118762	-0.03825397908141559	[213]	[188,291,134,255]	-1	hSpCas9	negative selection	5562909
88065796	88065819	4	+	27260156	BXPC3	viability	TTCACAAAGTACGACCAAGATGG	PKD2	ENSG00000118762	-0.09577128500237753	[1054]	[944,1075,1003,1112]	-2	hSpCas9	negative selection	5627159
88043279	88043302	4	+	27260156	BXPC3	viability	GGAATCATTGCAACTTATAGTGG	PKD2	ENSG00000118762	-0.10476686745291852	[149]	[120,155,159,147]	-2	hSpCas9	negative selection	5627160
88043272	88043295	4	-	27260156	BXPC3	viability	AAGTTGCAATGATTCCCCAGTGG	PKD2	ENSG00000118762	0.14289899397514327	[201]	[182,198,195,377]	3	hSpCas9	negative selection	5627161
88065370	88065393	4	+	27260156	A673	viability	ATAGGGCTACCATAAAGCTTTGG	PKD2	ENSG00000118762	-0.1853486983423187	[1202]	[1442,1233,1148,1274]	-4	hSpCas9	negative selection	5684158
88065473	88065496	4	+	27260156	A673	viability	GAACTTCGACAAGATCTCAAAGG	PKD2	ENSG00000118762	0.2828381608828505	[34]	[34,57,47,61]	6	hSpCas9	negative selection	5684159
88065846	88065869	4	+	27260156	A673	viability	TCAGCAGATGAGAGACGACTTGG	PKD2	ENSG00000118762	0.12770860304415832	[213]	[307,303,237,274]	3	hSpCas9	negative selection	5684160
88065796	88065819	4	+	27260156	A673	viability	TTCACAAAGTACGACCAAGATGG	PKD2	ENSG00000118762	-0.05543930227084992	[1054]	[1267,1292,1089,1227]	-1	hSpCas9	negative selection	5748410
88043279	88043302	4	+	27260156	A673	viability	GGAATCATTGCAACTTATAGTGG	PKD2	ENSG00000118762	0.29624055631324664	[149]	[230,266,174,210]	7	hSpCas9	negative selection	5748411
88043272	88043295	4	-	27260156	A673	viability	AAGTTGCAATGATTCCCCAGTGG	PKD2	ENSG00000118762	0.06417542428031209	[201]	[288,216,270,240]	1	hSpCas9	negative selection	5748412
88065370	88065393	4	+	27260156	A375	viability	ATAGGGCTACCATAAAGCTTTGG	PKD2	ENSG00000118762	-0.05200086773180579	[1202]	[1597,1537,1198,1134]	0	hSpCas9	negative selection	5805409
88065473	88065496	4	+	27260156	A375	viability	GAACTTCGACAAGATCTCAAAGG	PKD2	ENSG00000118762	-0.1642202596224034	[34]	[29,20,22,65]	-2	hSpCas9	negative selection	5805410
88065846	88065869	4	+	27260156	A375	viability	TCAGCAGATGAGAGACGACTTGG	PKD2	ENSG00000118762	0.4148245216525923	[213]	[389,240,334,350]	6	hSpCas9	negative selection	5805411
88065796	88065819	4	+	27260156	A375	viability	TTCACAAAGTACGACCAAGATGG	PKD2	ENSG00000118762	-0.04512850588914086	[1054]	[1177,1255,1291,1069]	0	hSpCas9	negative selection	5869661
88043279	88043302	4	+	27260156	A375	viability	GGAATCATTGCAACTTATAGTGG	PKD2	ENSG00000118762	-0.8575230571098047	[149]	[71,191,52,83]	-8	hSpCas9	negative selection	5869662
88043272	88043295	4	-	27260156	A375	viability	AAGTTGCAATGATTCCCCAGTGG	PKD2	ENSG00000118762	-0.6245442944069317	[201]	[147,219,156,101]	-7	hSpCas9	negative selection	5869663
88065370	88065393	4	+	27260156	COLO741	viability	ATAGGGCTACCATAAAGCTTTGG	PKD2	ENSG00000118762	0.00138007397087625	[1202]	[1831,1342,1466]	0	hSpCas9	negative selection	5926660
88065473	88065496	4	+	27260156	COLO741	viability	GAACTTCGACAAGATCTCAAAGG	PKD2	ENSG00000118762	-0.018248253556666594	[34]	[58,35,38]	0	hSpCas9	negative selection	5926661
88065846	88065869	4	+	27260156	COLO741	viability	TCAGCAGATGAGAGACGACTTGG	PKD2	ENSG00000118762	-0.3448544308936643	[213]	[250,204,193]	-6	hSpCas9	negative selection	5926662
88065796	88065819	4	+	27260156	COLO741	viability	TTCACAAAGTACGACCAAGATGG	PKD2	ENSG00000118762	-0.11556811332688088	[1054]	[1359,1017,1352]	-2	hSpCas9	negative selection	5990912
88043279	88043302	4	+	27260156	COLO741	viability	GGAATCATTGCAACTTATAGTGG	PKD2	ENSG00000118762	0.37911325918275374	[149]	[204,406,139]	7	hSpCas9	negative selection	5990913
88043272	88043295	4	-	27260156	COLO741	viability	AAGTTGCAATGATTCCCCAGTGG	PKD2	ENSG00000118762	0.203666158390702	[201]	[346,248,298]	4	hSpCas9	negative selection	5990914
88065370	88065393	4	+	27260156	CAL120	viability	ATAGGGCTACCATAAAGCTTTGG	PKD2	ENSG00000118762	-0.057531268708062466	[1202]	[1771,1153,1438]	-1	hSpCas9	negative selection	6047911
88065473	88065496	4	+	27260156	CAL120	viability	GAACTTCGACAAGATCTCAAAGG	PKD2	ENSG00000118762	0.4769927793716815	[34]	[123,41,25]	7	hSpCas9	negative selection	6047912
88065846	88065869	4	+	27260156	CAL120	viability	TCAGCAGATGAGAGACGACTTGG	PKD2	ENSG00000118762	-0.42973691138308934	[213]	[254,280,67]	-6	hSpCas9	negative selection	6047913
88065796	88065819	4	+	27260156	CAL120	viability	TTCACAAAGTACGACCAAGATGG	PKD2	ENSG00000118762	-0.08847175238097726	[1054]	[1319,1131,1263]	-1	hSpCas9	negative selection	6112163
88043279	88043302	4	+	27260156	CAL120	viability	GGAATCATTGCAACTTATAGTGG	PKD2	ENSG00000118762	0.664746647386981	[149]	[706,144,100]	8	hSpCas9	negative selection	6112164
88043272	88043295	4	-	27260156	CAL120	viability	AAGTTGCAATGATTCCCCAGTGG	PKD2	ENSG00000118762	0.07452778132401128	[201]	[291,292,213]	1	hSpCas9	negative selection	6112165
88065370	88065393	4	+	27260156	CADOES1	viability	ATAGGGCTACCATAAAGCTTTGG	PKD2	ENSG00000118762	-0.12201603519307747	[1202]	[982,1038,950,1143]	-2	hSpCas9	negative selection	6169162
88065473	88065496	4	+	27260156	CADOES1	viability	GAACTTCGACAAGATCTCAAAGG	PKD2	ENSG00000118762	1.1114694347541016	[34]	[74,73,44,87]	9	hSpCas9	negative selection	6169163
88065846	88065869	4	+	27260156	CADOES1	viability	TCAGCAGATGAGAGACGACTTGG	PKD2	ENSG00000118762	-0.18631378315720393	[213]	[171,194,99,234]	-3	hSpCas9	negative selection	6169164
88065796	88065819	4	+	27260156	CADOES1	viability	TTCACAAAGTACGACCAAGATGG	PKD2	ENSG00000118762	-0.13692662478756956	[1054]	[776,890,1027,872]	-2	hSpCas9	negative selection	6233414
88043279	88043302	4	+	27260156	CADOES1	viability	GGAATCATTGCAACTTATAGTGG	PKD2	ENSG00000118762	0.11025836064734729	[149]	[159,170,104,166]	2	hSpCas9	negative selection	6233415
88043272	88043295	4	-	27260156	CADOES1	viability	AAGTTGCAATGATTCCCCAGTGG	PKD2	ENSG00000118762	-0.3354394196459898	[201]	[159,182,119,131]	-5	hSpCas9	negative selection	6233416
88065370	88065393	4	+	27260156	EWS502	viability	ATAGGGCTACCATAAAGCTTTGG	PKD2	ENSG00000118762	-0.21549087852433102	[1202]	[1033,1271,1081,989]	-4	hSpCas9	negative selection	6290413
88065473	88065496	4	+	27260156	EWS502	viability	GAACTTCGACAAGATCTCAAAGG	PKD2	ENSG00000118762	0.6050895890298502	[34]	[19,65,83,59]	9	hSpCas9	negative selection	6290414
88065846	88065869	4	+	27260156	EWS502	viability	TCAGCAGATGAGAGACGACTTGG	PKD2	ENSG00000118762	-0.488531032574707	[213]	[141,152,187,165]	-7	hSpCas9	negative selection	6290415
88065796	88065819	4	+	27260156	EWS502	viability	TTCACAAAGTACGACCAAGATGG	PKD2	ENSG00000118762	0.0729759008664399	[1054]	[1120,1128,1201,1259]	1	hSpCas9	negative selection	6354665
88043279	88043302	4	+	27260156	EWS502	viability	GGAATCATTGCAACTTATAGTGG	PKD2	ENSG00000118762	-0.3882868843916747	[149]	[121,174,95,86]	-6	hSpCas9	negative selection	6354666
88043272	88043295	4	-	27260156	EWS502	viability	AAGTTGCAATGATTCCCCAGTGG	PKD2	ENSG00000118762	-0.19167342407411092	[201]	[213,100,210,225]	-3	hSpCas9	negative selection	6354667
88065370	88065393	4	+	27260156	EW8	viability	ATAGGGCTACCATAAAGCTTTGG	PKD2	ENSG00000118762	-0.06399346321540622	[1202]	[937,845,858,1096]	-1	hSpCas9	negative selection	6411664
88065473	88065496	4	+	27260156	EW8	viability	GAACTTCGACAAGATCTCAAAGG	PKD2	ENSG00000118762	0.04427077834332005	[34]	[27,53,16,19]	0	hSpCas9	negative selection	6411665
88065846	88065869	4	+	27260156	EW8	viability	TCAGCAGATGAGAGACGACTTGG	PKD2	ENSG00000118762	0.04152468749157667	[213]	[251,113,107,258]	0	hSpCas9	negative selection	6411666
88065796	88065819	4	+	27260156	EW8	viability	TTCACAAAGTACGACCAAGATGG	PKD2	ENSG00000118762	-0.10777207977658354	[1054]	[1018,835,692,665]	-2	hSpCas9	negative selection	6475916
88043279	88043302	4	+	27260156	EW8	viability	GGAATCATTGCAACTTATAGTGG	PKD2	ENSG00000118762	0.12223760102920922	[149]	[118,165,135,105]	2	hSpCas9	negative selection	6475917
88043272	88043295	4	-	27260156	EW8	viability	AAGTTGCAATGATTCCCCAGTGG	PKD2	ENSG00000118762	-0.5459542782019504	[201]	[119,121,112,93]	-7	hSpCas9	negative selection	6475918
88065370	88065393	4	+	27260156	CORL105	viability	ATAGGGCTACCATAAAGCTTTGG	PKD2	ENSG00000118762	-0.05912679011678312	[1202]	[1543,1145,1337,1386]	-1	hSpCas9	negative selection	6532915
88065473	88065496	4	+	27260156	CORL105	viability	GAACTTCGACAAGATCTCAAAGG	PKD2	ENSG00000118762	0.567821520291858	[34]	[27,43,129,50]	9	hSpCas9	negative selection	6532916
88065846	88065869	4	+	27260156	CORL105	viability	TCAGCAGATGAGAGACGACTTGG	PKD2	ENSG00000118762	-0.043698197433192254	[213]	[162,288,190,316]	-1	hSpCas9	negative selection	6532917
88065796	88065819	4	+	27260156	CORL105	viability	TTCACAAAGTACGACCAAGATGG	PKD2	ENSG00000118762	-0.10432297693948134	[1054]	[1239,1269,930,1120]	-2	hSpCas9	negative selection	6597167
88043279	88043302	4	+	27260156	CORL105	viability	GGAATCATTGCAACTTATAGTGG	PKD2	ENSG00000118762	0.07259064596498654	[149]	[198,235,194,109]	1	hSpCas9	negative selection	6597168
88043272	88043295	4	-	27260156	CORL105	viability	AAGTTGCAATGATTCCCCAGTGG	PKD2	ENSG00000118762	0.4687284392601797	[201]	[281,410,327,284]	8	hSpCas9	negative selection	6597169
88065370	88065393	4	+	27260156	HS294T	viability	ATAGGGCTACCATAAAGCTTTGG	PKD2	ENSG00000118762	-0.09359780299273046	[1202]	[275,377,378,784]	-1	hSpCas9	negative selection	6654166
88065473	88065496	4	+	27260156	HS294T	viability	GAACTTCGACAAGATCTCAAAGG	PKD2	ENSG00000118762	0.17446800823515263	[34]	[14,10,20,13]	2	hSpCas9	negative selection	6654167
88065846	88065869	4	+	27260156	HS294T	viability	TCAGCAGATGAGAGACGACTTGG	PKD2	ENSG00000118762	0.20990012677421221	[213]	[94,59,61,180]	3	hSpCas9	negative selection	6654168
88065796	88065819	4	+	27260156	HS294T	viability	TTCACAAAGTACGACCAAGATGG	PKD2	ENSG00000118762	-0.37775848676931734	[1054]	[281,270,338,377]	-5	hSpCas9	negative selection	6718418
88043279	88043302	4	+	27260156	HS294T	viability	GGAATCATTGCAACTTATAGTGG	PKD2	ENSG00000118762	-0.6278529324785602	[149]	[18,14,83,33]	-7	hSpCas9	negative selection	6718419
88043272	88043295	4	-	27260156	HS294T	viability	AAGTTGCAATGATTCCCCAGTGG	PKD2	ENSG00000118762	-0.33257696952739035	[201]	[31,41,82,100]	-5	hSpCas9	negative selection	6718420
88065370	88065393	4	+	27260156	HCC44	viability	ATAGGGCTACCATAAAGCTTTGG	PKD2	ENSG00000118762	0.02332072702114618	[1202]	[2183,846,1796,927]	0	hSpCas9	negative selection	6775417
88065473	88065496	4	+	27260156	HCC44	viability	GAACTTCGACAAGATCTCAAAGG	PKD2	ENSG00000118762	0.7426353758172506	[34]	[22,74,79,82]	9	hSpCas9	negative selection	6775418
88065846	88065869	4	+	27260156	HCC44	viability	TCAGCAGATGAGAGACGACTTGG	PKD2	ENSG00000118762	0.7268295981894978	[213]	[225,559,369,398]	9	hSpCas9	negative selection	6775419
88065796	88065819	4	+	27260156	HCC44	viability	TTCACAAAGTACGACCAAGATGG	PKD2	ENSG00000118762	-0.03670725303161815	[1054]	[1308,768,1504,1187]	0	hSpCas9	negative selection	6839669
88043279	88043302	4	+	27260156	HCC44	viability	GGAATCATTGCAACTTATAGTGG	PKD2	ENSG00000118762	-0.3473763034864954	[149]	[124,117,228,79]	-5	hSpCas9	negative selection	6839670
88043272	88043295	4	-	27260156	HCC44	viability	AAGTTGCAATGATTCCCCAGTGG	PKD2	ENSG00000118762	-0.646973708152504	[201]	[100,139,217,132]	-7	hSpCas9	negative selection	6839671
88065370	88065393	4	+	27260156	G402	viability	ATAGGGCTACCATAAAGCTTTGG	PKD2	ENSG00000118762	-0.12880311789279242	[1202]	[1172,962,2234,965]	-2	hSpCas9	negative selection	6896668
88065473	88065496	4	+	27260156	G402	viability	GAACTTCGACAAGATCTCAAAGG	PKD2	ENSG00000118762	0.49344020677558564	[34]	[0,72,151,8]	6	hSpCas9	negative selection	6896669
88065846	88065869	4	+	27260156	G402	viability	TCAGCAGATGAGAGACGACTTGG	PKD2	ENSG00000118762	0.46412132195549216	[213]	[337,688,208,225]	6	hSpCas9	negative selection	6896670
88065796	88065819	4	+	27260156	G402	viability	TTCACAAAGTACGACCAAGATGG	PKD2	ENSG00000118762	0.19822657375353891	[1054]	[1496,1630,1694,1108]	2	hSpCas9	negative selection	6960920
88043279	88043302	4	+	27260156	G402	viability	GGAATCATTGCAACTTATAGTGG	PKD2	ENSG00000118762	0.19841822370677553	[149]	[300,141,270,137]	2	hSpCas9	negative selection	6960921
88043272	88043295	4	-	27260156	G402	viability	AAGTTGCAATGATTCCCCAGTGG	PKD2	ENSG00000118762	0.165945340759321	[201]	[540,231,119,248]	2	hSpCas9	negative selection	6960922
88065370	88065393	4	+	27260156	L33	viability	ATAGGGCTACCATAAAGCTTTGG	PKD2	ENSG00000118762	-0.3230336805404219	[1202]	[1049,395,571,917]	-6	hSpCas9	negative selection	7017919
88065473	88065496	4	+	27260156	L33	viability	GAACTTCGACAAGATCTCAAAGG	PKD2	ENSG00000118762	0.8533578449372228	[34]	[76,13,63,39]	9	hSpCas9	negative selection	7017920
88065846	88065869	4	+	27260156	L33	viability	TCAGCAGATGAGAGACGACTTGG	PKD2	ENSG00000118762	-0.11260535546782391	[213]	[142,85,159,185]	-3	hSpCas9	negative selection	7017921
88065796	88065819	4	+	27260156	L33	viability	TTCACAAAGTACGACCAAGATGG	PKD2	ENSG00000118762	-0.15837879635020657	[1054]	[879,385,549,1083]	-4	hSpCas9	negative selection	7082171
88043279	88043302	4	+	27260156	L33	viability	GGAATCATTGCAACTTATAGTGG	PKD2	ENSG00000118762	-0.28092640957963777	[149]	[155,46,69,110]	-6	hSpCas9	negative selection	7082172
88043272	88043295	4	-	27260156	L33	viability	AAGTTGCAATGATTCCCCAGTGG	PKD2	ENSG00000118762	-0.2899488074083232	[201]	[142,72,106,169]	-6	hSpCas9	negative selection	7082173
88065370	88065393	4	+	27260156	K562	viability	ATAGGGCTACCATAAAGCTTTGG	PKD2	ENSG00000118762	-0.05956397166996252	[1202]	[637,1108,1501,838]	0	hSpCas9	negative selection	7139170
88065473	88065496	4	+	27260156	K562	viability	GAACTTCGACAAGATCTCAAAGG	PKD2	ENSG00000118762	0.006788813475178568	[34]	[12,1,21,78]	0	hSpCas9	negative selection	7139171
88065846	88065869	4	+	27260156	K562	viability	TCAGCAGATGAGAGACGACTTGG	PKD2	ENSG00000118762	0.3047379108761211	[213]	[319,112,440,81]	4	hSpCas9	negative selection	7139172
88065796	88065819	4	+	27260156	K562	viability	TTCACAAAGTACGACCAAGATGG	PKD2	ENSG00000118762	0.09046317925452985	[1054]	[1029,771,1005,1147]	1	hSpCas9	negative selection	7203422
88043279	88043302	4	+	27260156	K562	viability	GGAATCATTGCAACTTATAGTGG	PKD2	ENSG00000118762	-0.5615326088521881	[149]	[58,13,210,71]	-6	hSpCas9	negative selection	7203423
88043272	88043295	4	-	27260156	K562	viability	AAGTTGCAATGATTCCCCAGTGG	PKD2	ENSG00000118762	0.2803718140746546	[201]	[322,159,169,221]	3	hSpCas9	negative selection	7203424
88065370	88065393	4	+	27260156	HT29	viability	ATAGGGCTACCATAAAGCTTTGG	PKD2	ENSG00000118762	-0.20370521485937765	[1202]	[1332,1279,1383,1099]	-4	hSpCas9	negative selection	7260421
88065473	88065496	4	+	27260156	HT29	viability	GAACTTCGACAAGATCTCAAAGG	PKD2	ENSG00000118762	0.6938333832834527	[34]	[55,63,107,47]	9	hSpCas9	negative selection	7260422
88065846	88065869	4	+	27260156	HT29	viability	TCAGCAGATGAGAGACGACTTGG	PKD2	ENSG00000118762	0.038042187395471494	[213]	[222,205,246,368]	0	hSpCas9	negative selection	7260423
88065796	88065819	4	+	27260156	HT29	viability	TTCACAAAGTACGACCAAGATGG	PKD2	ENSG00000118762	0.03161715998087122	[1054]	[1475,1526,1146,1136]	0	hSpCas9	negative selection	7324673
88043279	88043302	4	+	27260156	HT29	viability	GGAATCATTGCAACTTATAGTGG	PKD2	ENSG00000118762	-0.07048814896821809	[149]	[274,131,147,145]	-1	hSpCas9	negative selection	7324674
88043272	88043295	4	-	27260156	HT29	viability	AAGTTGCAATGATTCCCCAGTGG	PKD2	ENSG00000118762	-0.3134217519011868	[201]	[308,111,142,222]	-6	hSpCas9	negative selection	7324675
88065370	88065393	4	+	27260156	MHHES1	viability	ATAGGGCTACCATAAAGCTTTGG	PKD2	ENSG00000118762	0.10618525026203329	[1202]	[1627,1503,1535,1214]	2	hSpCas9	negative selection	7381672
88065473	88065496	4	+	27260156	MHHES1	viability	GAACTTCGACAAGATCTCAAAGG	PKD2	ENSG00000118762	0.29534559824010076	[34]	[54,14,81,39]	5	hSpCas9	negative selection	7381673
88065846	88065869	4	+	27260156	MHHES1	viability	TCAGCAGATGAGAGACGACTTGG	PKD2	ENSG00000118762	0.08245581301557703	[213]	[182,367,310,174]	1	hSpCas9	negative selection	7381674
88065796	88065819	4	+	27260156	MHHES1	viability	TTCACAAAGTACGACCAAGATGG	PKD2	ENSG00000118762	-0.05855146454664806	[1054]	[1182,1168,1109,1093]	-1	hSpCas9	negative selection	7445924
88043279	88043302	4	+	27260156	MHHES1	viability	GGAATCATTGCAACTTATAGTGG	PKD2	ENSG00000118762	-0.3295421186704506	[149]	[74,144,129,169]	-6	hSpCas9	negative selection	7445925
88043272	88043295	4	-	27260156	MHHES1	viability	AAGTTGCAATGATTCCCCAGTGG	PKD2	ENSG00000118762	-0.23154699169887105	[201]	[194,199,251,137]	-4	hSpCas9	negative selection	7445926
88065370	88065393	4	+	27260156	MEWO	viability	ATAGGGCTACCATAAAGCTTTGG	PKD2	ENSG00000118762	-0.05682856592371732	[1202]	[1296,1171,817]	-1	hSpCas9	negative selection	7502923
88065473	88065496	4	+	27260156	MEWO	viability	GAACTTCGACAAGATCTCAAAGG	PKD2	ENSG00000118762	0.2877612838405641	[34]	[55,42,23]	6	hSpCas9	negative selection	7502924
88065846	88065869	4	+	27260156	MEWO	viability	TCAGCAGATGAGAGACGACTTGG	PKD2	ENSG00000118762	-0.1911132169241625	[213]	[189,155,182]	-4	hSpCas9	negative selection	7502925
88065796	88065819	4	+	27260156	MEWO	viability	TTCACAAAGTACGACCAAGATGG	PKD2	ENSG00000118762	0.18653727540463905	[1054]	[1427,826,1174]	4	hSpCas9	negative selection	7567175
88043279	88043302	4	+	27260156	MEWO	viability	GGAATCATTGCAACTTATAGTGG	PKD2	ENSG00000118762	0.37540834320242356	[149]	[217,192,141]	7	hSpCas9	negative selection	7567176
88043272	88043295	4	-	27260156	MEWO	viability	AAGTTGCAATGATTCCCCAGTGG	PKD2	ENSG00000118762	-0.17999969860288645	[201]	[256,142,117]	-4	hSpCas9	negative selection	7567177
88065370	88065393	4	+	27260156	LNCAPCLONEFGC	viability	ATAGGGCTACCATAAAGCTTTGG	PKD2	ENSG00000118762	0.12359562170923999	[1202]	[991,1364,1226,1161]	2	hSpCas9	negative selection	7624174
88065473	88065496	4	+	27260156	LNCAPCLONEFGC	viability	GAACTTCGACAAGATCTCAAAGG	PKD2	ENSG00000118762	0.6349503129855694	[34]	[126,6,47,15]	8	hSpCas9	negative selection	7624175
88065846	88065869	4	+	27260156	LNCAPCLONEFGC	viability	TCAGCAGATGAGAGACGACTTGG	PKD2	ENSG00000118762	-0.28853905570852323	[213]	[116,121,360,67]	-4	hSpCas9	negative selection	7624176
88065796	88065819	4	+	27260156	LNCAPCLONEFGC	viability	TTCACAAAGTACGACCAAGATGG	PKD2	ENSG00000118762	-0.05912953569989776	[1054]	[928,712,1234,851]	-1	hSpCas9	negative selection	7688426
88043279	88043302	4	+	27260156	LNCAPCLONEFGC	viability	GGAATCATTGCAACTTATAGTGG	PKD2	ENSG00000118762	-0.5557014093260466	[149]	[72,95,79,118]	-7	hSpCas9	negative selection	7688427
88043272	88043295	4	-	27260156	LNCAPCLONEFGC	viability	AAGTTGCAATGATTCCCCAGTGG	PKD2	ENSG00000118762	-0.6487632824965894	[201]	[127,109,136,94]	-7	hSpCas9	negative selection	7688428
88065370	88065393	4	+	27260156	PANC0327	viability	ATAGGGCTACCATAAAGCTTTGG	PKD2	ENSG00000118762	-0.30333989425670116	[1202]	[712,943,838,944]	-4	hSpCas9	negative selection	7745425
88065473	88065496	4	+	27260156	PANC0327	viability	GAACTTCGACAAGATCTCAAAGG	PKD2	ENSG00000118762	-0.7953189981503033	[34]	[2,28,17,18]	-8	hSpCas9	negative selection	7745426
88065846	88065869	4	+	27260156	PANC0327	viability	TCAGCAGATGAGAGACGACTTGG	PKD2	ENSG00000118762	0.5423128483055499	[213]	[364,200,151,405]	7	hSpCas9	negative selection	7745427
88065796	88065819	4	+	27260156	PANC0327	viability	TTCACAAAGTACGACCAAGATGG	PKD2	ENSG00000118762	-0.12945699300698355	[1054]	[638,685,1025,1079]	-2	hSpCas9	negative selection	7809677
88043279	88043302	4	+	27260156	PANC0327	viability	GGAATCATTGCAACTTATAGTGG	PKD2	ENSG00000118762	0.7601034525980739	[149]	[256,258,262,121]	9	hSpCas9	negative selection	7809678
88043272	88043295	4	-	27260156	PANC0327	viability	AAGTTGCAATGATTCCCCAGTGG	PKD2	ENSG00000118762	-0.010924724906151262	[201]	[169,244,165,121]	0	hSpCas9	negative selection	7809679
88065370	88065393	4	+	27260156	NCIH2009	viability	ATAGGGCTACCATAAAGCTTTGG	PKD2	ENSG00000118762	-0.556973954341935	[1202]	[1476,1064,950]	-6	hSpCas9	negative selection	7866676
88065473	88065496	4	+	27260156	NCIH2009	viability	GAACTTCGACAAGATCTCAAAGG	PKD2	ENSG00000118762	1.6113116701264438	[34]	[94,215,124]	9	hSpCas9	negative selection	7866677
88065846	88065869	4	+	27260156	NCIH2009	viability	TCAGCAGATGAGAGACGACTTGG	PKD2	ENSG00000118762	0.17697877000265694	[213]	[343,428,239]	2	hSpCas9	negative selection	7866678
88065796	88065819	4	+	27260156	NCIH2009	viability	TTCACAAAGTACGACCAAGATGG	PKD2	ENSG00000118762	-0.06758438913429665	[1054]	[1281,1605,1300]	-1	hSpCas9	negative selection	7930928
88043279	88043302	4	+	27260156	NCIH2009	viability	GGAATCATTGCAACTTATAGTGG	PKD2	ENSG00000118762	-0.25602307521273926	[149]	[271,189,82]	-3	hSpCas9	negative selection	7930929
88043272	88043295	4	-	27260156	NCIH2009	viability	AAGTTGCAATGATTCCCCAGTGG	PKD2	ENSG00000118762	-0.4229092521322422	[201]	[190,173,262]	-5	hSpCas9	negative selection	7930930
88065370	88065393	4	+	27260156	NCIH1373	viability	ATAGGGCTACCATAAAGCTTTGG	PKD2	ENSG00000118762	-0.11959456279290448	[1202]	[1262,1154,1257,340]	-1	hSpCas9	negative selection	7987927
88065473	88065496	4	+	27260156	NCIH1373	viability	GAACTTCGACAAGATCTCAAAGG	PKD2	ENSG00000118762	-1.8371170436991489	[34]	[24,9,6,0]	-9	hSpCas9	negative selection	7987928
88065846	88065869	4	+	27260156	NCIH1373	viability	TCAGCAGATGAGAGACGACTTGG	PKD2	ENSG00000118762	-0.19473289572444274	[213]	[339,209,138,43]	-2	hSpCas9	negative selection	7987929
88065796	88065819	4	+	27260156	NCIH1373	viability	TTCACAAAGTACGACCAAGATGG	PKD2	ENSG00000118762	-0.6709385313162133	[1054]	[1176,612,601,171]	-6	hSpCas9	negative selection	8052179
88043279	88043302	4	+	27260156	NCIH1373	viability	GGAATCATTGCAACTTATAGTGG	PKD2	ENSG00000118762	0.2778288391224182	[149]	[56,97,83,154]	2	hSpCas9	negative selection	8052180
88043272	88043295	4	-	27260156	NCIH1373	viability	AAGTTGCAATGATTCCCCAGTGG	PKD2	ENSG00000118762	-0.17541084668674167	[201]	[52,74,501,39]	-2	hSpCas9	negative selection	8052181
88065370	88065393	4	+	27260156	PATU8902	viability	ATAGGGCTACCATAAAGCTTTGG	PKD2	ENSG00000118762	0.008282763216236999	[1202]	[1755,2371,1012,1771]	0	hSpCas9	negative selection	8109178
88065473	88065496	4	+	27260156	PATU8902	viability	GAACTTCGACAAGATCTCAAAGG	PKD2	ENSG00000118762	0.8204396301572214	[34]	[136,130,6,88]	8	hSpCas9	negative selection	8109179
88065846	88065869	4	+	27260156	PATU8902	viability	TCAGCAGATGAGAGACGACTTGG	PKD2	ENSG00000118762	0.3013368376626274	[213]	[275,271,552,310]	3	hSpCas9	negative selection	8109180
88065796	88065819	4	+	27260156	PATU8902	viability	TTCACAAAGTACGACCAAGATGG	PKD2	ENSG00000118762	0.08593591985889559	[1054]	[1875,1495,1079,1938]	0	hSpCas9	negative selection	8173430
88043279	88043302	4	+	27260156	PATU8902	viability	GGAATCATTGCAACTTATAGTGG	PKD2	ENSG00000118762	-0.4946406878751237	[149]	[280,117,70,138]	-5	hSpCas9	negative selection	8173431
88043272	88043295	4	-	27260156	PATU8902	viability	AAGTTGCAATGATTCCCCAGTGG	PKD2	ENSG00000118762	0.08252295898904705	[201]	[433,132,151,533]	0	hSpCas9	negative selection	8173432
88065370	88065393	4	+	27260156	PANC1	viability	ATAGGGCTACCATAAAGCTTTGG	PKD2	ENSG00000118762	-0.36153765901870427	[1202]	[731,949,771,783]	-5	hSpCas9	negative selection	8230429
88065473	88065496	4	+	27260156	PANC1	viability	GAACTTCGACAAGATCTCAAAGG	PKD2	ENSG00000118762	0.6314147364346101	[34]	[40,72,63,17]	8	hSpCas9	negative selection	8230430
88065846	88065869	4	+	27260156	PANC1	viability	TCAGCAGATGAGAGACGACTTGG	PKD2	ENSG00000118762	0.557549358424862	[213]	[223,345,220,297]	8	hSpCas9	negative selection	8230431
88065796	88065819	4	+	27260156	PANC1	viability	TTCACAAAGTACGACCAAGATGG	PKD2	ENSG00000118762	-0.18046925550106852	[1054]	[755,1001,573,879]	-3	hSpCas9	negative selection	8294681
88043279	88043302	4	+	27260156	PANC1	viability	GGAATCATTGCAACTTATAGTGG	PKD2	ENSG00000118762	-0.9576628928762776	[149]	[28,72,73,86]	-8	hSpCas9	negative selection	8294682
88043272	88043295	4	-	27260156	PANC1	viability	AAGTTGCAATGATTCCCCAGTGG	PKD2	ENSG00000118762	0.2820681601374202	[201]	[211,379,104,181]	4	hSpCas9	negative selection	8294683
88065370	88065393	4	+	27260156	PANC0813	viability	ATAGGGCTACCATAAAGCTTTGG	PKD2	ENSG00000118762	-0.281391423061488	[1202]	[1378,1214,1209,880]	-4	hSpCas9	negative selection	8351680
88065473	88065496	4	+	27260156	PANC0813	viability	GAACTTCGACAAGATCTCAAAGG	PKD2	ENSG00000118762	0.19872577926146917	[34]	[23,46,74,40]	3	hSpCas9	negative selection	8351681
88065846	88065869	4	+	27260156	PANC0813	viability	TCAGCAGATGAGAGACGACTTGG	PKD2	ENSG00000118762	-0.5412531920905317	[213]	[183,165,139,199]	-7	hSpCas9	negative selection	8351682
88065796	88065819	4	+	27260156	PANC0813	viability	TTCACAAAGTACGACCAAGATGG	PKD2	ENSG00000118762	-0.019629311915105863	[1054]	[1175,1323,1189,1194]	0	hSpCas9	negative selection	8415932
88043279	88043302	4	+	27260156	PANC0813	viability	GGAATCATTGCAACTTATAGTGG	PKD2	ENSG00000118762	-0.1608963590360637	[149]	[185,187,126,132]	-3	hSpCas9	negative selection	8415933
88043272	88043295	4	-	27260156	PANC0813	viability	AAGTTGCAATGATTCCCCAGTGG	PKD2	ENSG00000118762	-0.22978017500619097	[201]	[334,183,239,69]	-4	hSpCas9	negative selection	8415934
88065370	88065393	4	+	27260156	RDES	viability	ATAGGGCTACCATAAAGCTTTGG	PKD2	ENSG00000118762	-0.151685774631948	[1202]	[932,1202,1183,1775]	-3	hSpCas9	negative selection	8472931
88065473	88065496	4	+	27260156	RDES	viability	GAACTTCGACAAGATCTCAAAGG	PKD2	ENSG00000118762	-0.667203157158371	[34]	[8,8,60,28]	-8	hSpCas9	negative selection	8472932
88065846	88065869	4	+	27260156	RDES	viability	TCAGCAGATGAGAGACGACTTGG	PKD2	ENSG00000118762	0.035619150437293357	[213]	[287,251,230,213]	0	hSpCas9	negative selection	8472933
88065796	88065819	4	+	27260156	RDES	viability	TTCACAAAGTACGACCAAGATGG	PKD2	ENSG00000118762	-0.3849618080315609	[1054]	[689,855,1045,1202]	-6	hSpCas9	negative selection	8537183
88043279	88043302	4	+	27260156	RDES	viability	GGAATCATTGCAACTTATAGTGG	PKD2	ENSG00000118762	0.17926009586182312	[149]	[148,262,166,198]	3	hSpCas9	negative selection	8537184
88043272	88043295	4	-	27260156	RDES	viability	AAGTTGCAATGATTCCCCAGTGG	PKD2	ENSG00000118762	-0.3585478096077561	[201]	[115,169,296,151]	-6	hSpCas9	negative selection	8537185
88065370	88065393	4	+	27260156	PC3	viability	ATAGGGCTACCATAAAGCTTTGG	PKD2	ENSG00000118762	-0.13752263298839562	[1202]	[737,990,1971,1047]	-3	hSpCas9	negative selection	8594182
88065473	88065496	4	+	27260156	PC3	viability	GAACTTCGACAAGATCTCAAAGG	PKD2	ENSG00000118762	0.24849054641841706	[34]	[14,46,96,36]	5	hSpCas9	negative selection	8594183
88065846	88065869	4	+	27260156	PC3	viability	TCAGCAGATGAGAGACGACTTGG	PKD2	ENSG00000118762	0.18295733223900246	[213]	[143,316,179,321]	4	hSpCas9	negative selection	8594184
88065796	88065819	4	+	27260156	PC3	viability	TTCACAAAGTACGACCAAGATGG	PKD2	ENSG00000118762	-0.2754472917436026	[1054]	[518,1068,1364,769]	-6	hSpCas9	negative selection	8658434
88043279	88043302	4	+	27260156	PC3	viability	GGAATCATTGCAACTTATAGTGG	PKD2	ENSG00000118762	0.2408714756879693	[149]	[129,240,113,193]	5	hSpCas9	negative selection	8658435
88043272	88043295	4	-	27260156	PC3	viability	AAGTTGCAATGATTCCCCAGTGG	PKD2	ENSG00000118762	-0.39714650336325485	[201]	[100,121,326,137]	-7	hSpCas9	negative selection	8658436
88065370	88065393	4	+	27260156	PATU8988T	viability	ATAGGGCTACCATAAAGCTTTGG	PKD2	ENSG00000118762	-0.37235621872364366	[1202]	[918,854,1009,793]	-6	hSpCas9	negative selection	8715433
88065473	88065496	4	+	27260156	PATU8988T	viability	GAACTTCGACAAGATCTCAAAGG	PKD2	ENSG00000118762	0.5354759254145307	[34]	[39,113,7,39]	8	hSpCas9	negative selection	8715434
88065846	88065869	4	+	27260156	PATU8988T	viability	TCAGCAGATGAGAGACGACTTGG	PKD2	ENSG00000118762	-0.16825954074731064	[213]	[222,191,132,189]	-3	hSpCas9	negative selection	8715435
88065796	88065819	4	+	27260156	PATU8988T	viability	TTCACAAAGTACGACCAAGATGG	PKD2	ENSG00000118762	0.11000959017591994	[1054]	[1318,878,888,1312]	2	hSpCas9	negative selection	8779685
88043279	88043302	4	+	27260156	PATU8988T	viability	GGAATCATTGCAACTTATAGTGG	PKD2	ENSG00000118762	0.051094464346327806	[149]	[203,206,108,80]	0	hSpCas9	negative selection	8779686
88043272	88043295	4	-	27260156	PATU8988T	viability	AAGTTGCAATGATTCCCCAGTGG	PKD2	ENSG00000118762	-0.035011888320224616	[201]	[310,114,174,150]	0	hSpCas9	negative selection	8779687
88065370	88065393	4	+	27260156	T47D	viability	ATAGGGCTACCATAAAGCTTTGG	PKD2	ENSG00000118762	-0.05963952608904455	[1202]	[1388,1225,1359,1415]	-1	hSpCas9	negative selection	8836684
88065473	88065496	4	+	27260156	T47D	viability	GAACTTCGACAAGATCTCAAAGG	PKD2	ENSG00000118762	0.000905637513017421	[34]	[27,37,58,37]	0	hSpCas9	negative selection	8836685
88065846	88065869	4	+	27260156	T47D	viability	TCAGCAGATGAGAGACGACTTGG	PKD2	ENSG00000118762	0.046890572917341	[213]	[317,209,220,286]	1	hSpCas9	negative selection	8836686
88065796	88065819	4	+	27260156	T47D	viability	TTCACAAAGTACGACCAAGATGG	PKD2	ENSG00000118762	-0.16694601894062877	[1054]	[1026,1077,1066,1211]	-4	hSpCas9	negative selection	8900936
88043279	88043302	4	+	27260156	T47D	viability	GGAATCATTGCAACTTATAGTGG	PKD2	ENSG00000118762	-0.13373564703001817	[149]	[171,104,186,177]	-3	hSpCas9	negative selection	8900937
88043272	88043295	4	-	27260156	T47D	viability	AAGTTGCAATGATTCCCCAGTGG	PKD2	ENSG00000118762	-0.16233571972322802	[201]	[187,214,171,267]	-4	hSpCas9	negative selection	8900938
88065370	88065393	4	+	27260156	SU8686	viability	ATAGGGCTACCATAAAGCTTTGG	PKD2	ENSG00000118762	-0.14334672674548554	[1202]	[930,1034,1090,1315]	-3	hSpCas9	negative selection	8957935
88065473	88065496	4	+	27260156	SU8686	viability	GAACTTCGACAAGATCTCAAAGG	PKD2	ENSG00000118762	0.6785674526793088	[34]	[89,42,15,71]	9	hSpCas9	negative selection	8957936
88065846	88065869	4	+	27260156	SU8686	viability	TCAGCAGATGAGAGACGACTTGG	PKD2	ENSG00000118762	-0.3159207581764316	[213]	[168,186,144,177]	-5	hSpCas9	negative selection	8957937
88065796	88065819	4	+	27260156	SU8686	viability	TTCACAAAGTACGACCAAGATGG	PKD2	ENSG00000118762	-0.3565674635742764	[1054]	[713,935,789,816]	-5	hSpCas9	negative selection	9022187
88043279	88043302	4	+	27260156	SU8686	viability	GGAATCATTGCAACTTATAGTGG	PKD2	ENSG00000118762	0.002822579463288566	[149]	[138,123,134,210]	0	hSpCas9	negative selection	9022188
88043272	88043295	4	-	27260156	SU8686	viability	AAGTTGCAATGATTCCCCAGTGG	PKD2	ENSG00000118762	-0.07669016465511502	[201]	[160,240,180,167]	-1	hSpCas9	negative selection	9022189
88065370	88065393	4	+	27260156	SKES1	viability	ATAGGGCTACCATAAAGCTTTGG	PKD2	ENSG00000118762	-0.11614895264506986	[1202]	[983,1308,1125,1015]	-3	hSpCas9	negative selection	9079186
88065473	88065496	4	+	27260156	SKES1	viability	GAACTTCGACAAGATCTCAAAGG	PKD2	ENSG00000118762	0.25647044304367395	[34]	[18,21,52,63]	5	hSpCas9	negative selection	9079187
88065846	88065869	4	+	27260156	SKES1	viability	TCAGCAGATGAGAGACGACTTGG	PKD2	ENSG00000118762	-0.09439819711880215	[213]	[177,268,119,232]	-2	hSpCas9	negative selection	9079188
88065796	88065819	4	+	27260156	SKES1	viability	TTCACAAAGTACGACCAAGATGG	PKD2	ENSG00000118762	-0.1658116468483899	[1054]	[1028,778,954,968]	-4	hSpCas9	negative selection	9143438
88043279	88043302	4	+	27260156	SKES1	viability	GGAATCATTGCAACTTATAGTGG	PKD2	ENSG00000118762	0.045451651376126945	[149]	[169,169,110,167]	1	hSpCas9	negative selection	9143439
88043272	88043295	4	-	27260156	SKES1	viability	AAGTTGCAATGATTCCCCAGTGG	PKD2	ENSG00000118762	0.1383036683007779	[201]	[116,249,192,303]	3	hSpCas9	negative selection	9143440
88065370	88065393	4	+	27260156	TOV112D	viability	ATAGGGCTACCATAAAGCTTTGG	PKD2	ENSG00000118762	-0.10666078774876486	[1202]	[1396,1372,994,803]	-2	hSpCas9	negative selection	9200437
88065473	88065496	4	+	27260156	TOV112D	viability	GAACTTCGACAAGATCTCAAAGG	PKD2	ENSG00000118762	0.26444381187108235	[34]	[31,77,11,53]	5	hSpCas9	negative selection	9200438
88065846	88065869	4	+	27260156	TOV112D	viability	TCAGCAGATGAGAGACGACTTGG	PKD2	ENSG00000118762	-0.127825352215738	[213]	[182,243,208,159]	-2	hSpCas9	negative selection	9200439
88065796	88065819	4	+	27260156	TOV112D	viability	TTCACAAAGTACGACCAAGATGG	PKD2	ENSG00000118762	-0.07298058118462492	[1054]	[1110,1247,1037,696]	-1	hSpCas9	negative selection	9264689
88043279	88043302	4	+	27260156	TOV112D	viability	GGAATCATTGCAACTTATAGTGG	PKD2	ENSG00000118762	0.6386373114497106	[149]	[243,253,209,232]	9	hSpCas9	negative selection	9264690
88043272	88043295	4	-	27260156	TOV112D	viability	AAGTTGCAATGATTCCCCAGTGG	PKD2	ENSG00000118762	0.24776039280908302	[201]	[241,128,348,213]	5	hSpCas9	negative selection	9264691
88065370	88065393	4	+	27260156	TC71	viability	ATAGGGCTACCATAAAGCTTTGG	PKD2	ENSG00000118762	-0.14816589285912496	[1202]	[1126,1168,1178,1180]	-4	hSpCas9	negative selection	9321688
88065473	88065496	4	+	27260156	TC71	viability	GAACTTCGACAAGATCTCAAAGG	PKD2	ENSG00000118762	0.3187851011453233	[34]	[48,56,29,51]	7	hSpCas9	negative selection	9321689
88065846	88065869	4	+	27260156	TC71	viability	TCAGCAGATGAGAGACGACTTGG	PKD2	ENSG00000118762	-0.2743791643033291	[213]	[208,109,200,240]	-6	hSpCas9	negative selection	9321690
88065796	88065819	4	+	27260156	TC71	viability	TTCACAAAGTACGACCAAGATGG	PKD2	ENSG00000118762	-0.045404857372460805	[1054]	[900,1124,984,1398]	-1	hSpCas9	negative selection	9385940
88043279	88043302	4	+	27260156	TC71	viability	GGAATCATTGCAACTTATAGTGG	PKD2	ENSG00000118762	-0.10301303430080311	[149]	[106,161,167,162]	-3	hSpCas9	negative selection	9385941
88043272	88043295	4	-	27260156	TC71	viability	AAGTTGCAATGATTCCCCAGTGG	PKD2	ENSG00000118762	0.17542318851672167	[201]	[191,230,290,264]	4	hSpCas9	negative selection	9385942
88065370	88065393	4	+	27260156	TC32	viability	ATAGGGCTACCATAAAGCTTTGG	PKD2	ENSG00000118762	0.09250599439536455	[1202]	[1050,1170,1359,1221]	1	hSpCas9	negative selection	9442939
88065473	88065496	4	+	27260156	TC32	viability	GAACTTCGACAAGATCTCAAAGG	PKD2	ENSG00000118762	0.8694072319890518	[34]	[38,47,72,87]	9	hSpCas9	negative selection	9442940
88065846	88065869	4	+	27260156	TC32	viability	TCAGCAGATGAGAGACGACTTGG	PKD2	ENSG00000118762	-0.05497969288784188	[213]	[170,89,314,254]	-1	hSpCas9	negative selection	9442941
88065796	88065819	4	+	27260156	TC32	viability	TTCACAAAGTACGACCAAGATGG	PKD2	ENSG00000118762	-0.21901470752761565	[1054]	[674,497,1338,1104]	-4	hSpCas9	negative selection	9507191
88043279	88043302	4	+	27260156	TC32	viability	GGAATCATTGCAACTTATAGTGG	PKD2	ENSG00000118762	-0.5490873420005575	[149]	[84,33,165,134]	-8	hSpCas9	negative selection	9507192
88043272	88043295	4	-	27260156	TC32	viability	AAGTTGCAATGATTCCCCAGTGG	PKD2	ENSG00000118762	-0.3190512451941683	[201]	[118,114,176,214]	-5	hSpCas9	negative selection	9507193
88008073	88008096	4	+	27869803	HPAFII	viability after 27 days	ATGGACGTAGAGTGGCGCCCGGG	PKD2	ENSG00000118762	0.5292603500417935	[155]	[185,61,NaN]	4	hSpCas9	negative selection	9589252
88038371	88038394	4	+	27869803	HPAFII	viability after 27 days	CGGCAACTCCGAGTCAGAAATGG	PKD2	ENSG00000118762	0.9556953128677803	[752]	[769,765,NaN]	7	hSpCas9	negative selection	9589253
88043376	88043399	4	+	27869803	HPAFII	viability after 27 days	TCTGGCTGGACCGAGGAACCAGG	PKD2	ENSG00000118762	-0.21305595885919404	[460]	[177,234,NaN]	-1	hSpCas9	negative selection	9589254
88056217	88056240	4	-	27869803	HPAFII	viability after 27 days	CGACCTGAGTGCCAAAGACAAGG	PKD2	ENSG00000118762	0.8533480931547879	[1518]	[1684,1240,NaN]	7	hSpCas9	negative selection	9589255
88065857	88065880	4	+	27869803	HPAFII	viability after 27 days	GAGACGACTTGGAGAAAGAGAGG	PKD2	ENSG00000118762	0.93386215533437	[124]	[106,140,NaN]	7	hSpCas9	negative selection	9589256
88067995	88068018	4	+	27869803	HPAFII	viability after 27 days	ATAGCGGACATAGCTCCAGAAGG	PKD2	ENSG00000118762	-0.7109843124864426	[166]	[21,79,NaN]	-5	hSpCas9	negative selection	9589257
88008073	88008096	4	+	27869803	HPAFII	viability after 15 days	ATGGACGTAGAGTGGCGCCCGGG	PKD2	ENSG00000118762	0.487194675507311	[155]	[501,68,NaN]	5	hSpCas9	negative selection	9671701
88038371	88038394	4	+	27869803	HPAFII	viability after 15 days	CGGCAACTCCGAGTCAGAAATGG	PKD2	ENSG00000118762	0.735628942269513	[752]	[1735,1105,NaN]	7	hSpCas9	negative selection	9671702
88043376	88043399	4	+	27869803	HPAFII	viability after 15 days	TCTGGCTGGACCGAGGAACCAGG	PKD2	ENSG00000118762	-0.11686482336440218	[460]	[623,352,NaN]	-1	hSpCas9	negative selection	9671703
88056217	88056240	4	-	27869803	HPAFII	viability after 15 days	CGACCTGAGTGCCAAAGACAAGG	PKD2	ENSG00000118762	0.26923898046662265	[1518]	[2781,1460,NaN]	3	hSpCas9	negative selection	9671704
88065857	88065880	4	+	27869803	HPAFII	viability after 15 days	GAGACGACTTGGAGAAAGAGAGG	PKD2	ENSG00000118762	0.6540078867313384	[124]	[285,164,NaN]	7	hSpCas9	negative selection	9671705
88067995	88068018	4	+	27869803	HPAFII	viability after 15 days	ATAGCGGACATAGCTCCAGAAGG	PKD2	ENSG00000118762	-0.5931607183450942	[166]	[208,62,NaN]	-6	hSpCas9	negative selection	9671706
88008073	88008096	4	+	27869803	ASPC1	viability after 36 days	ATGGACGTAGAGTGGCGCCCGGG	PKD2	ENSG00000118762	-1.1740106310449414	[507]	[111,78,53]	-8	hSpCas9	negative selection	9754150
88038371	88038394	4	+	27869803	ASPC1	viability after 36 days	CGGCAACTCCGAGTCAGAAATGG	PKD2	ENSG00000118762	0.5819530246721503	[2062]	[991,1029,1164]	6	hSpCas9	negative selection	9754151
88043376	88043399	4	+	27869803	ASPC1	viability after 36 days	TCTGGCTGGACCGAGGAACCAGG	PKD2	ENSG00000118762	0.9297755147772271	[894]	[510,584,655]	8	hSpCas9	negative selection	9754152
88056217	88056240	4	-	27869803	ASPC1	viability after 36 days	CGACCTGAGTGCCAAAGACAAGG	PKD2	ENSG00000118762	-0.009211569702236577	[3726]	[1367,1636,952]	0	hSpCas9	negative selection	9754153
88065857	88065880	4	+	27869803	ASPC1	viability after 36 days	GAGACGACTTGGAGAAAGAGAGG	PKD2	ENSG00000118762	0.6661058312763847	[265]	[200,144,109]	6	hSpCas9	negative selection	9754154
88067995	88068018	4	+	27869803	ASPC1	viability after 36 days	ATAGCGGACATAGCTCCAGAAGG	PKD2	ENSG00000118762	0.2665774621975503	[303]	[23,264,89]	2	hSpCas9	negative selection	9754155
88008073	88008096	4	+	27869803	PATU8988S	viability after 35 days	ATGGACGTAGAGTGGCGCCCGGG	PKD2	ENSG00000118762	0.3486678049370322	[347]	[166,189,NaN]	4	hSpCas9	negative selection	9836599
88038371	88038394	4	+	27869803	PATU8988S	viability after 35 days	CGGCAACTCCGAGTCAGAAATGG	PKD2	ENSG00000118762	0.2600516737280436	[1662]	[831,771,NaN]	3	hSpCas9	negative selection	9836600
88043376	88043399	4	+	27869803	PATU8988S	viability after 35 days	TCTGGCTGGACCGAGGAACCAGG	PKD2	ENSG00000118762	-0.4217726461118931	[907]	[270,274,NaN]	-4	hSpCas9	negative selection	9836601
88056217	88056240	4	-	27869803	PATU8988S	viability after 35 days	CGACCTGAGTGCCAAAGACAAGG	PKD2	ENSG00000118762	0.5437251491334907	[3117]	[1647,2013,NaN]	6	hSpCas9	negative selection	9836602
88065857	88065880	4	+	27869803	PATU8988S	viability after 35 days	GAGACGACTTGGAGAAAGAGAGG	PKD2	ENSG00000118762	0.5916808022877698	[322]	[214,176,NaN]	6	hSpCas9	negative selection	9836603
88067995	88068018	4	+	27869803	PATU8988S	viability after 35 days	ATAGCGGACATAGCTCCAGAAGG	PKD2	ENSG00000118762	-1.2965239791354324	[289]	[68,25,NaN]	-8	hSpCas9	negative selection	9836604
88008073	88008096	4	+	27869803	PATU8988S	viability after 31 days	ATGGACGTAGAGTGGCGCCCGGG	PKD2	ENSG00000118762	0.40763670910456795	[347]	[136,243,NaN]	5	hSpCas9	negative selection	9919048
88038371	88038394	4	+	27869803	PATU8988S	viability after 31 days	CGGCAACTCCGAGTCAGAAATGG	PKD2	ENSG00000118762	0.21193391069008416	[1662]	[771,762,NaN]	2	hSpCas9	negative selection	9919049
88043376	88043399	4	+	27869803	PATU8988S	viability after 31 days	TCTGGCTGGACCGAGGAACCAGG	PKD2	ENSG00000118762	-0.45942191784501	[907]	[250,278,NaN]	-5	hSpCas9	negative selection	9919050
88056217	88056240	4	-	27869803	PATU8988S	viability after 31 days	CGACCTGAGTGCCAAAGACAAGG	PKD2	ENSG00000118762	0.5165394273921016	[3117]	[1485,2150,NaN]	6	hSpCas9	negative selection	9919051
88065857	88065880	4	+	27869803	PATU8988S	viability after 31 days	GAGACGACTTGGAGAAAGAGAGG	PKD2	ENSG00000118762	0.34377339695264175	[322]	[206,107,NaN]	4	hSpCas9	negative selection	9919052
88067995	88068018	4	+	27869803	PATU8988S	viability after 31 days	ATAGCGGACATAGCTCCAGAAGG	PKD2	ENSG00000118762	-0.5474267229289584	[289]	[90,63,NaN]	-6	hSpCas9	negative selection	9919053
88008073	88008096	4	+	27869803	HPAFII	viability after 35 days	ATGGACGTAGAGTGGCGCCCGGG	PKD2	ENSG00000118762	0.5483613171309774	[155]	[162,61,NaN]	3	hSpCas9	negative selection	10001497
88038371	88038394	4	+	27869803	HPAFII	viability after 35 days	CGGCAACTCCGAGTCAGAAATGG	PKD2	ENSG00000118762	1.1220140413320732	[752]	[800,861,NaN]	7	hSpCas9	negative selection	10001498
88043376	88043399	4	+	27869803	HPAFII	viability after 35 days	TCTGGCTGGACCGAGGAACCAGG	PKD2	ENSG00000118762	0.37162486552697105	[460]	[197,418,NaN]	2	hSpCas9	negative selection	10001499
88056217	88056240	4	-	27869803	HPAFII	viability after 35 days	CGACCTGAGTGCCAAAGACAAGG	PKD2	ENSG00000118762	0.9904843361557818	[1518]	[1493,1565,NaN]	6	hSpCas9	negative selection	10001500
88065857	88065880	4	+	27869803	HPAFII	viability after 35 days	GAGACGACTTGGAGAAAGAGAGG	PKD2	ENSG00000118762	1.2596852530333604	[124]	[135,168,NaN]	8	hSpCas9	negative selection	10001501
88067995	88068018	4	+	27869803	HPAFII	viability after 35 days	ATAGCGGACATAGCTCCAGAAGG	PKD2	ENSG00000118762	-1.8097792988340569	[166]	[17,30,NaN]	-7	hSpCas9	negative selection	10001502
88008073	88008096	4	+	27869803	HPAFII	viability after 31 days	ATGGACGTAGAGTGGCGCCCGGG	PKD2	ENSG00000118762	0.35899956101401176	[155]	[140,80,NaN]	2	hSpCas9	negative selection	10083946
88038371	88038394	4	+	27869803	HPAFII	viability after 31 days	CGGCAACTCCGAGTCAGAAATGG	PKD2	ENSG00000118762	0.9660519650690291	[752]	[736,921,NaN]	7	hSpCas9	negative selection	10083947
88043376	88043399	4	+	27869803	HPAFII	viability after 31 days	TCTGGCTGGACCGAGGAACCAGG	PKD2	ENSG00000118762	-0.2943967661889746	[460]	[131,296,NaN]	-2	hSpCas9	negative selection	10083948
88056217	88056240	4	-	27869803	HPAFII	viability after 31 days	CGACCTGAGTGCCAAAGACAAGG	PKD2	ENSG00000118762	0.8572824442234759	[1518]	[1686,1388,NaN]	6	hSpCas9	negative selection	10083949
88065857	88065880	4	+	27869803	HPAFII	viability after 31 days	GAGACGACTTGGAGAAAGAGAGG	PKD2	ENSG00000118762	1.1969668309360213	[124]	[156,164,NaN]	8	hSpCas9	negative selection	10083950
88067995	88068018	4	+	27869803	HPAFII	viability after 31 days	ATAGCGGACATAGCTCCAGAAGG	PKD2	ENSG00000118762	-1.6098307147604594	[166]	[12,49,NaN]	-7	hSpCas9	negative selection	10083951
88007898	88007921	4	+	28162770	P31FUJ	viability	GATGCAGCGCATCCGGCAGGCGG	PKD2	ENSG00000118762	-1.2328022044143783	[5]	[2]	-7	hSpCas9	negative selection	10211824
88074932	88074955	4	+	28162770	P31FUJ	viability	GGGAAGGCTGTTGGATGGGGTGG	PKD2	ENSG00000118762	-1.1503400442224057	[288]	[152]	-7	hSpCas9	negative selection	10211825
88007962	88007985	4	-	28162770	P31FUJ	viability	CGGGAGCACGACGAGAGCGGAGG	PKD2	ENSG00000118762	0.4666886843331647	[116]	[189]	5	hSpCas9	negative selection	10211826
88008034	88008057	4	+	28162770	P31FUJ	viability	GAGGAGGTGGAAGGGGAAGAAGG	PKD2	ENSG00000118762	-8.109319150979378	[234]	[0]	-9	hSpCas9	negative selection	10211827
88043317	88043340	4	+	28162770	P31FUJ	viability	GGATTTGTCAAGAACAAGAGAGG	PKD2	ENSG00000118762	0.20042841163043487	[196]	[265]	2	hSpCas9	negative selection	10211828
88043394	88043417	4	-	28162770	P31FUJ	viability	GAAGTCAATAAAAGTTGCCCTGG	PKD2	ENSG00000118762	0.10599970903738015	[271]	[343]	1	hSpCas9	negative selection	10211829
88065431	88065454	4	+	28162770	P31FUJ	viability	TCAGAGAGTCTGCGGCAAGGAGG	PKD2	ENSG00000118762	0.5253798756615232	[404]	[684]	6	hSpCas9	negative selection	10211830
88065857	88065880	4	+	28162770	P31FUJ	viability	GAGACGACTTGGAGAAAGAGAGG	PKD2	ENSG00000118762	0.2370376801030522	[225]	[312]	2	hSpCas9	negative selection	10211831
88068000	88068023	4	+	28162770	P31FUJ	viability	GGACATAGCTCCAGAAGGAGGGG	PKD2	ENSG00000118762	0.13211181543862888	[204]	[263]	1	hSpCas9	negative selection	10211832
88074901	88074924	4	+	28162770	P31FUJ	viability	AGCGAGCCAAACTGAAGAGGAGG	PKD2	ENSG00000118762	0.20393036596378417	[197]	[267]	2	hSpCas9	negative selection	10211833
88007898	88007921	4	+	28162770	TF1	viability	GATGCAGCGCATCCGGCAGGCGG	PKD2	ENSG00000118762	NaN	[NaN]	[1]	1	hSpCas9	negative selection	10381190
88074932	88074955	4	+	28162770	TF1	viability	GGGAAGGCTGTTGGATGGGGTGG	PKD2	ENSG00000118762	NaN	[NaN]	[85]	1	hSpCas9	negative selection	10381191
88007962	88007985	4	-	28162770	TF1	viability	CGGGAGCACGACGAGAGCGGAGG	PKD2	ENSG00000118762	NaN	[NaN]	[74]	1	hSpCas9	negative selection	10381192
88008034	88008057	4	+	28162770	TF1	viability	GAGGAGGTGGAAGGGGAAGAAGG	PKD2	ENSG00000118762	NaN	[NaN]	[0]	1	hSpCas9	negative selection	10381193
88043317	88043340	4	+	28162770	TF1	viability	GGATTTGTCAAGAACAAGAGAGG	PKD2	ENSG00000118762	NaN	[NaN]	[176]	1	hSpCas9	negative selection	10381194
88043394	88043417	4	-	28162770	TF1	viability	GAAGTCAATAAAAGTTGCCCTGG	PKD2	ENSG00000118762	NaN	[NaN]	[390]	1	hSpCas9	negative selection	10381195
88065431	88065454	4	+	28162770	TF1	viability	TCAGAGAGTCTGCGGCAAGGAGG	PKD2	ENSG00000118762	NaN	[NaN]	[425]	1	hSpCas9	negative selection	10381196
88065857	88065880	4	+	28162770	TF1	viability	GAGACGACTTGGAGAAAGAGAGG	PKD2	ENSG00000118762	NaN	[NaN]	[316]	1	hSpCas9	negative selection	10381197
88068000	88068023	4	+	28162770	TF1	viability	GGACATAGCTCCAGAAGGAGGGG	PKD2	ENSG00000118762	NaN	[NaN]	[271]	1	hSpCas9	negative selection	10381198
88074901	88074924	4	+	28162770	TF1	viability	AGCGAGCCAAACTGAAGAGGAGG	PKD2	ENSG00000118762	NaN	[NaN]	[213]	1	hSpCas9	negative selection	10381199
88007898	88007921	4	+	28162770	SKM1	viability	GATGCAGCGCATCCGGCAGGCGG	PKD2	ENSG00000118762	-0.8220016980220048	[0]	[0]	-6	hSpCas9	negative selection	10550556
88074932	88074955	4	+	28162770	SKM1	viability	GGGAAGGCTGTTGGATGGGGTGG	PKD2	ENSG00000118762	0.329064276168991	[76]	[170]	3	hSpCas9	negative selection	10550557
88007962	88007985	4	-	28162770	SKM1	viability	CGGGAGCACGACGAGAGCGGAGG	PKD2	ENSG00000118762	0.3706433799203904	[34]	[79]	3	hSpCas9	negative selection	10550558
88008034	88008057	4	+	28162770	SKM1	viability	GAGGAGGTGGAAGGGGAAGAAGG	PKD2	ENSG00000118762	-3.332963617299385	[56]	[9]	-9	hSpCas9	negative selection	10550559
88043317	88043340	4	+	28162770	SKM1	viability	GGATTTGTCAAGAACAAGAGAGG	PKD2	ENSG00000118762	0.35106301095087405	[50]	[114]	3	hSpCas9	negative selection	10550560
88043394	88043417	4	-	28162770	SKM1	viability	GAAGTCAATAAAAGTTGCCCTGG	PKD2	ENSG00000118762	0.31148130745224656	[97]	[214]	3	hSpCas9	negative selection	10550561
88065431	88065454	4	+	28162770	SKM1	viability	TCAGAGAGTCTGCGGCAAGGAGG	PKD2	ENSG00000118762	0.25861676218627905	[86]	[183]	2	hSpCas9	negative selection	10550562
88065857	88065880	4	+	28162770	SKM1	viability	GAGACGACTTGGAGAAAGAGAGG	PKD2	ENSG00000118762	-0.2733810443645696	[66]	[97]	-2	hSpCas9	negative selection	10550563
88068000	88068023	4	+	28162770	SKM1	viability	GGACATAGCTCCAGAAGGAGGGG	PKD2	ENSG00000118762	-0.15903668529957624	[47]	[75]	-1	hSpCas9	negative selection	10550564
88074901	88074924	4	+	28162770	SKM1	viability	AGCGAGCCAAACTGAAGAGGAGG	PKD2	ENSG00000118762	0.9853532240355984	[37]	[132]	8	hSpCas9	negative selection	10550565
88007898	88007921	4	+	28162770	SKM1	viability	GATGCAGCGCATCCGGCAGGCGG	PKD2	ENSG00000118762	-0.8220016980220048	[0]	[0]	-6	hSpCas9	negative selection	10719922
88074932	88074955	4	+	28162770	SKM1	viability	GGGAAGGCTGTTGGATGGGGTGG	PKD2	ENSG00000118762	0.329064276168991	[76]	[170]	3	hSpCas9	negative selection	10719923
88007962	88007985	4	-	28162770	SKM1	viability	CGGGAGCACGACGAGAGCGGAGG	PKD2	ENSG00000118762	0.3706433799203904	[34]	[79]	3	hSpCas9	negative selection	10719924
88008034	88008057	4	+	28162770	SKM1	viability	GAGGAGGTGGAAGGGGAAGAAGG	PKD2	ENSG00000118762	-3.332963617299385	[56]	[9]	-9	hSpCas9	negative selection	10719925
88043317	88043340	4	+	28162770	SKM1	viability	GGATTTGTCAAGAACAAGAGAGG	PKD2	ENSG00000118762	0.35106301095087405	[50]	[114]	3	hSpCas9	negative selection	10719926
88043394	88043417	4	-	28162770	SKM1	viability	GAAGTCAATAAAAGTTGCCCTGG	PKD2	ENSG00000118762	0.31148130745224656	[97]	[214]	3	hSpCas9	negative selection	10719927
88065431	88065454	4	+	28162770	SKM1	viability	TCAGAGAGTCTGCGGCAAGGAGG	PKD2	ENSG00000118762	0.25861676218627905	[86]	[183]	2	hSpCas9	negative selection	10719928
88065857	88065880	4	+	28162770	SKM1	viability	GAGACGACTTGGAGAAAGAGAGG	PKD2	ENSG00000118762	-0.2733810443645696	[66]	[97]	-2	hSpCas9	negative selection	10719929
88068000	88068023	4	+	28162770	SKM1	viability	GGACATAGCTCCAGAAGGAGGGG	PKD2	ENSG00000118762	-0.15903668529957624	[47]	[75]	-1	hSpCas9	negative selection	10719930
88074901	88074924	4	+	28162770	SKM1	viability	AGCGAGCCAAACTGAAGAGGAGG	PKD2	ENSG00000118762	0.9853532240355984	[37]	[132]	8	hSpCas9	negative selection	10719931
88007898	88007921	4	+	28162770	PL21	viability	GATGCAGCGCATCCGGCAGGCGG	PKD2	ENSG00000118762	3.3700646159316325	[1]	[8]	9	hSpCas9	negative selection	10889288
88074932	88074955	4	+	28162770	PL21	viability	GGGAAGGCTGTTGGATGGGGTGG	PKD2	ENSG00000118762	-0.45521221412323404	[251]	[79]	-3	hSpCas9	negative selection	10889289
88007962	88007985	4	-	28162770	PL21	viability	CGGGAGCACGACGAGAGCGGAGG	PKD2	ENSG00000118762	-0.2193992770244645	[106]	[39]	-1	hSpCas9	negative selection	10889290
88008034	88008057	4	+	28162770	PL21	viability	GAGGAGGTGGAAGGGGAAGAAGG	PKD2	ENSG00000118762	-6.694678148818624	[237]	[0]	-9	hSpCas9	negative selection	10889291
88043317	88043340	4	+	28162770	PL21	viability	GGATTTGTCAAGAACAAGAGAGG	PKD2	ENSG00000118762	-0.5610735259235633	[199]	[58]	-4	hSpCas9	negative selection	10889292
88043394	88043417	4	-	28162770	PL21	viability	GAAGTCAATAAAAGTTGCCCTGG	PKD2	ENSG00000118762	0.7185168634608485	[302]	[216]	6	hSpCas9	negative selection	10889293
88065431	88065454	4	+	28162770	PL21	viability	TCAGAGAGTCTGCGGCAAGGAGG	PKD2	ENSG00000118762	0.6821838022649096	[304]	[212]	6	hSpCas9	negative selection	10889294
88065857	88065880	4	+	28162770	PL21	viability	GAGACGACTTGGAGAAAGAGAGG	PKD2	ENSG00000118762	1.3282959659800022	[182]	[199]	9	hSpCas9	negative selection	10889295
88068000	88068023	4	+	28162770	PL21	viability	GGACATAGCTCCAGAAGGAGGGG	PKD2	ENSG00000118762	0.5138000933930821	[139]	[86]	4	hSpCas9	negative selection	10889296
88074901	88074924	4	+	28162770	PL21	viability	AGCGAGCCAAACTGAAGAGGAGG	PKD2	ENSG00000118762	0.7075411319168234	[120]	[85]	6	hSpCas9	negative selection	10889297
88007898	88007921	4	+	28162770	P31FUJ	viability	GATGCAGCGCATCCGGCAGGCGG	PKD2	ENSG00000118762	-1.2328022044143783	[5]	[2]	-7	hSpCas9	negative selection	11058654
88074932	88074955	4	+	28162770	P31FUJ	viability	GGGAAGGCTGTTGGATGGGGTGG	PKD2	ENSG00000118762	-1.1503400442224057	[288]	[152]	-7	hSpCas9	negative selection	11058655
88007962	88007985	4	-	28162770	P31FUJ	viability	CGGGAGCACGACGAGAGCGGAGG	PKD2	ENSG00000118762	0.4666886843331647	[116]	[189]	5	hSpCas9	negative selection	11058656
88008034	88008057	4	+	28162770	P31FUJ	viability	GAGGAGGTGGAAGGGGAAGAAGG	PKD2	ENSG00000118762	-8.109319150979378	[234]	[0]	-9	hSpCas9	negative selection	11058657
88043317	88043340	4	+	28162770	P31FUJ	viability	GGATTTGTCAAGAACAAGAGAGG	PKD2	ENSG00000118762	0.20042841163043487	[196]	[265]	2	hSpCas9	negative selection	11058658
88043394	88043417	4	-	28162770	P31FUJ	viability	GAAGTCAATAAAAGTTGCCCTGG	PKD2	ENSG00000118762	0.10599970903738015	[271]	[343]	1	hSpCas9	negative selection	11058659
88065431	88065454	4	+	28162770	P31FUJ	viability	TCAGAGAGTCTGCGGCAAGGAGG	PKD2	ENSG00000118762	0.5253798756615232	[404]	[684]	6	hSpCas9	negative selection	11058660
88065857	88065880	4	+	28162770	P31FUJ	viability	GAGACGACTTGGAGAAAGAGAGG	PKD2	ENSG00000118762	0.2370376801030522	[225]	[312]	2	hSpCas9	negative selection	11058661
88068000	88068023	4	+	28162770	P31FUJ	viability	GGACATAGCTCCAGAAGGAGGGG	PKD2	ENSG00000118762	0.13211181543862888	[204]	[263]	1	hSpCas9	negative selection	11058662
88074901	88074924	4	+	28162770	P31FUJ	viability	AGCGAGCCAAACTGAAGAGGAGG	PKD2	ENSG00000118762	0.20393036596378417	[197]	[267]	2	hSpCas9	negative selection	11058663
88007898	88007921	4	+	28162770	OCIAML5	viability	GATGCAGCGCATCCGGCAGGCGG	PKD2	ENSG00000118762	-0.8520665708639967	[0]	[0]	-5	hSpCas9	negative selection	11228020
88074932	88074955	4	+	28162770	OCIAML5	viability	GGGAAGGCTGTTGGATGGGGTGG	PKD2	ENSG00000118762	-0.7690772061929654	[151]	[160]	-5	hSpCas9	negative selection	11228021
88007962	88007985	4	-	28162770	OCIAML5	viability	CGGGAGCACGACGAGAGCGGAGG	PKD2	ENSG00000118762	0.2947748174652741	[69]	[154]	2	hSpCas9	negative selection	11228022
88008034	88008057	4	+	28162770	OCIAML5	viability	GAGGAGGTGGAAGGGGAAGAAGG	PKD2	ENSG00000118762	-7.91815576132177	[133]	[0]	-9	hSpCas9	negative selection	11228023
88043317	88043340	4	+	28162770	OCIAML5	viability	GGATTTGTCAAGAACAAGAGAGG	PKD2	ENSG00000118762	0.5726488423172007	[129]	[348]	5	hSpCas9	negative selection	11228024
88043394	88043417	4	-	28162770	OCIAML5	viability	GAAGTCAATAAAAGTTGCCCTGG	PKD2	ENSG00000118762	0.28168481802483036	[174]	[383]	2	hSpCas9	negative selection	11228025
88065431	88065454	4	+	28162770	OCIAML5	viability	TCAGAGAGTCTGCGGCAAGGAGG	PKD2	ENSG00000118762	0.18492763661820466	[230]	[473]	1	hSpCas9	negative selection	11228026
88065857	88065880	4	+	28162770	OCIAML5	viability	GAGACGACTTGGAGAAAGAGAGG	PKD2	ENSG00000118762	0.8840600031908101	[171]	[572]	7	hSpCas9	negative selection	11228027
88068000	88068023	4	+	28162770	OCIAML5	viability	GGACATAGCTCCAGAAGGAGGGG	PKD2	ENSG00000118762	0.5054854337540867	[79]	[204]	4	hSpCas9	negative selection	11228028
88074901	88074924	4	+	28162770	OCIAML5	viability	AGCGAGCCAAACTGAAGAGGAGG	PKD2	ENSG00000118762	-0.27981512189239466	[75]	[112]	-2	hSpCas9	negative selection	11228029
88007898	88007921	4	+	28162770	EOL1	viability	GATGCAGCGCATCCGGCAGGCGG	PKD2	ENSG00000118762	0.924547771570535	[0]	[0]	7	hSpCas9	negative selection	11397386
88074932	88074955	4	+	28162770	EOL1	viability	GGGAAGGCTGTTGGATGGGGTGG	PKD2	ENSG00000118762	-0.42385253467801887	[274]	[107]	-3	hSpCas9	negative selection	11397387
88007962	88007985	4	-	28162770	EOL1	viability	CGGGAGCACGACGAGAGCGGAGG	PKD2	ENSG00000118762	1.5837284383887553	[220]	[348]	9	hSpCas9	negative selection	11397388
88008034	88008057	4	+	28162770	EOL1	viability	GAGGAGGTGGAAGGGGAAGAAGG	PKD2	ENSG00000118762	-6.310668690123498	[451]	[2]	-9	hSpCas9	negative selection	11397389
88043317	88043340	4	+	28162770	EOL1	viability	GGATTTGTCAAGAACAAGAGAGG	PKD2	ENSG00000118762	0.4220474310413513	[356]	[251]	4	hSpCas9	negative selection	11397390
88043394	88043417	4	-	28162770	EOL1	viability	GAAGTCAATAAAAGTTGCCCTGG	PKD2	ENSG00000118762	-0.7443027976710597	[654]	[205]	-5	hSpCas9	negative selection	11397391
88065431	88065454	4	+	28162770	EOL1	viability	TCAGAGAGTCTGCGGCAAGGAGG	PKD2	ENSG00000118762	-1.071876774205638	[402]	[100]	-6	hSpCas9	negative selection	11397392
88065857	88065880	4	+	28162770	EOL1	viability	GAGACGACTTGGAGAAAGAGAGG	PKD2	ENSG00000118762	-0.18573428344437615	[230]	[106]	-1	hSpCas9	negative selection	11397393
88068000	88068023	4	+	28162770	EOL1	viability	GGACATAGCTCCAGAAGGAGGGG	PKD2	ENSG00000118762	-1.7535241335421032	[223]	[34]	-8	hSpCas9	negative selection	11397394
88074901	88074924	4	+	28162770	EOL1	viability	AGCGAGCCAAACTGAAGAGGAGG	PKD2	ENSG00000118762	0.004516076273949565	[192]	[101]	0	hSpCas9	negative selection	11397395
88007898	88007921	4	+	28162770	MOLM13	viability	GATGCAGCGCATCCGGCAGGCGG	PKD2	ENSG00000118762	2.7158168949881647	[3]	[18]	9	hSpCas9	negative selection	11566752
88074932	88074955	4	+	28162770	MOLM13	viability	GGGAAGGCTGTTGGATGGGGTGG	PKD2	ENSG00000118762	-1.284800564914644	[245]	[72]	-6	hSpCas9	negative selection	11566753
88007962	88007985	4	-	28162770	MOLM13	viability	CGGGAGCACGACGAGAGCGGAGG	PKD2	ENSG00000118762	2.1699845158637325	[133]	[435]	9	hSpCas9	negative selection	11566754
88008034	88008057	4	+	28162770	MOLM13	viability	GAGGAGGTGGAAGGGGAAGAAGG	PKD2	ENSG00000118762	-7.962563170120953	[344]	[0]	-9	hSpCas9	negative selection	11566755
88043317	88043340	4	+	28162770	MOLM13	viability	GGATTTGTCAAGAACAAGAGAGG	PKD2	ENSG00000118762	0.08337674927919353	[264]	[202]	0	hSpCas9	negative selection	11566756
88043394	88043417	4	-	28162770	MOLM13	viability	GAAGTCAATAAAAGTTGCCCTGG	PKD2	ENSG00000118762	0.661661124941259	[479]	[548]	5	hSpCas9	negative selection	11566757
88065431	88065454	4	+	28162770	MOLM13	viability	TCAGAGAGTCTGCGGCAAGGAGG	PKD2	ENSG00000118762	0.17628582351401423	[458]	[374]	1	hSpCas9	negative selection	11566758
88065857	88065880	4	+	28162770	MOLM13	viability	GAGACGACTTGGAGAAAGAGAGG	PKD2	ENSG00000118762	-0.4773181456150417	[309]	[160]	-3	hSpCas9	negative selection	11566759
88068000	88068023	4	+	28162770	MOLM13	viability	GGACATAGCTCCAGAAGGAGGGG	PKD2	ENSG00000118762	0.8131566025192483	[232]	[295]	6	hSpCas9	negative selection	11566760
88074901	88074924	4	+	28162770	MOLM13	viability	AGCGAGCCAAACTGAAGAGGAGG	PKD2	ENSG00000118762	-0.4037865214798818	[171]	[93]	-2	hSpCas9	negative selection	11566761
88007898	88007921	4	+	28162770	HEL	viability	GATGCAGCGCATCCGGCAGGCGG	PKD2	ENSG00000118762	-1.942223668720799	[5]	[0]	-8	hSpCas9	negative selection	11736118
88074932	88074955	4	+	28162770	HEL	viability	GGGAAGGCTGTTGGATGGGGTGG	PKD2	ENSG00000118762	-0.1646160900572472	[251]	[143]	-1	hSpCas9	negative selection	11736119
88007962	88007985	4	-	28162770	HEL	viability	CGGGAGCACGACGAGAGCGGAGG	PKD2	ENSG00000118762	1.1345919283300316	[159]	[224]	8	hSpCas9	negative selection	11736120
88008034	88008057	4	+	28162770	HEL	viability	GAGGAGGTGGAAGGGGAAGAAGG	PKD2	ENSG00000118762	-5.001117357774368	[349]	[6]	-9	hSpCas9	negative selection	11736121
88043317	88043340	4	+	28162770	HEL	viability	GGATTTGTCAAGAACAAGAGAGG	PKD2	ENSG00000118762	1.0884559493686274	[220]	[300]	8	hSpCas9	negative selection	11736122
88043394	88043417	4	-	28162770	HEL	viability	GAAGTCAATAAAAGTTGCCCTGG	PKD2	ENSG00000118762	0.9958485821359989	[356]	[455]	8	hSpCas9	negative selection	11736123
88065431	88065454	4	+	28162770	HEL	viability	TCAGAGAGTCTGCGGCAAGGAGG	PKD2	ENSG00000118762	0.03201323521411903	[338]	[221]	0	hSpCas9	negative selection	11736124
88065857	88065880	4	+	28162770	HEL	viability	GAGACGACTTGGAGAAAGAGAGG	PKD2	ENSG00000118762	0.08668902319443966	[246]	[167]	0	hSpCas9	negative selection	11736125
88068000	88068023	4	+	28162770	HEL	viability	GGACATAGCTCCAGAAGGAGGGG	PKD2	ENSG00000118762	-0.3803447811126844	[251]	[123]	-3	hSpCas9	negative selection	11736126
88074901	88074924	4	+	28162770	HEL	viability	AGCGAGCCAAACTGAAGAGGAGG	PKD2	ENSG00000118762	0.43415221018893957	[155]	[134]	3	hSpCas9	negative selection	11736127
88007898	88007921	4	+	28162770	MV411	viability	GATGCAGCGCATCCGGCAGGCGG	PKD2	ENSG00000118762	0.24743755078277552	[0]	[0]	2	hSpCas9	negative selection	11905484
88074932	88074955	4	+	28162770	MV411	viability	GGGAAGGCTGTTGGATGGGGTGG	PKD2	ENSG00000118762	-0.6741745505325086	[196]	[103]	-5	hSpCas9	negative selection	11905485
88007962	88007985	4	-	28162770	MV411	viability	CGGGAGCACGACGAGAGCGGAGG	PKD2	ENSG00000118762	0.027471866840867443	[98]	[84]	0	hSpCas9	negative selection	11905486
88008034	88008057	4	+	28162770	MV411	viability	GAGGAGGTGGAAGGGGAAGAAGG	PKD2	ENSG00000118762	-7.824024811773849	[268]	[0]	-9	hSpCas9	negative selection	11905487
88043317	88043340	4	+	28162770	MV411	viability	GGATTTGTCAAGAACAAGAGAGG	PKD2	ENSG00000118762	1.1208570542176322	[124]	[228]	8	hSpCas9	negative selection	11905488
88043394	88043417	4	-	28162770	MV411	viability	GAAGTCAATAAAAGTTGCCCTGG	PKD2	ENSG00000118762	0.5535406785084552	[329]	[407]	5	hSpCas9	negative selection	11905489
88065431	88065454	4	+	28162770	MV411	viability	TCAGAGAGTCTGCGGCAAGGAGG	PKD2	ENSG00000118762	0.14288161974018554	[328]	[305]	1	hSpCas9	negative selection	11905490
88065857	88065880	4	+	28162770	MV411	viability	GAGACGACTTGGAGAAAGAGAGG	PKD2	ENSG00000118762	0.6266298511148968	[162]	[211]	5	hSpCas9	negative selection	11905491
88068000	88068023	4	+	28162770	MV411	viability	GGACATAGCTCCAGAAGGAGGGG	PKD2	ENSG00000118762	1.436663108184024	[131]	[300]	9	hSpCas9	negative selection	11905492
88074901	88074924	4	+	28162770	MV411	viability	AGCGAGCCAAACTGAAGAGGAGG	PKD2	ENSG00000118762	-0.0827110509095555	[131]	[104]	0	hSpCas9	negative selection	11905493
88007898	88007921	4	+	28162770	MONOMAC1	viability	GATGCAGCGCATCCGGCAGGCGG	PKD2	ENSG00000118762	-1.1970368470595538	[1]	[0]	-7	hSpCas9	negative selection	12074850
88074932	88074955	4	+	28162770	MONOMAC1	viability	GGGAAGGCTGTTGGATGGGGTGG	PKD2	ENSG00000118762	0.0892673380970873	[122]	[149]	0	hSpCas9	negative selection	12074851
88007962	88007985	4	-	28162770	MONOMAC1	viability	CGGGAGCACGACGAGAGCGGAGG	PKD2	ENSG00000118762	0.07257021269772634	[72]	[87]	0	hSpCas9	negative selection	12074852
88008034	88008057	4	+	28162770	MONOMAC1	viability	GAGGAGGTGGAAGGGGAAGAAGG	PKD2	ENSG00000118762	-5.3345403708094885	[175]	[4]	-9	hSpCas9	negative selection	12074853
88043317	88043340	4	+	28162770	MONOMAC1	viability	GGATTTGTCAAGAACAAGAGAGG	PKD2	ENSG00000118762	0.37153121541093376	[117]	[174]	3	hSpCas9	negative selection	12074854
88043394	88043417	4	-	28162770	MONOMAC1	viability	GAAGTCAATAAAAGTTGCCCTGG	PKD2	ENSG00000118762	-0.41343052777455847	[279]	[240]	-4	hSpCas9	negative selection	12074855
88065431	88065454	4	+	28162770	MONOMAC1	viability	TCAGAGAGTCTGCGGCAAGGAGG	PKD2	ENSG00000118762	0.16871974944807178	[200]	[258]	1	hSpCas9	negative selection	12074856
88065857	88065880	4	+	28162770	MONOMAC1	viability	GAGACGACTTGGAGAAAGAGAGG	PKD2	ENSG00000118762	0.6533867968899363	[131]	[237]	6	hSpCas9	negative selection	12074857
88068000	88068023	4	+	28162770	MONOMAC1	viability	GGACATAGCTCCAGAAGGAGGGG	PKD2	ENSG00000118762	0.325803941753805	[86]	[124]	3	hSpCas9	negative selection	12074858
88074901	88074924	4	+	28162770	MONOMAC1	viability	AGCGAGCCAAACTGAAGAGGAGG	PKD2	ENSG00000118762	-0.0912421830369568	[91]	[98]	-1	hSpCas9	negative selection	12074859
88007898	88007921	4	+	28162770	OCIAML2	viability	GATGCAGCGCATCCGGCAGGCGG	PKD2	ENSG00000118762	-2.4706298252421615	[0]	[0]	-8	hSpCas9	negative selection	12244216
88074932	88074955	4	+	28162770	OCIAML2	viability	GGGAAGGCTGTTGGATGGGGTGG	PKD2	ENSG00000118762	-0.9457883169585759	[48]	[140]	-6	hSpCas9	negative selection	12244217
88007962	88007985	4	-	28162770	OCIAML2	viability	CGGGAGCACGACGAGAGCGGAGG	PKD2	ENSG00000118762	-0.45682402571713093	[25]	[104]	-4	hSpCas9	negative selection	12244218
88008034	88008057	4	+	28162770	OCIAML2	viability	GAGGAGGTGGAAGGGGAAGAAGG	PKD2	ENSG00000118762	-5.718557338685747	[56]	[5]	-9	hSpCas9	negative selection	12244219
88043317	88043340	4	+	28162770	OCIAML2	viability	GGATTTGTCAAGAACAAGAGAGG	PKD2	ENSG00000118762	0.45136766275656587	[37]	[287]	4	hSpCas9	negative selection	12244220
88043394	88043417	4	-	28162770	OCIAML2	viability	GAAGTCAATAAAAGTTGCCCTGG	PKD2	ENSG00000118762	-0.20621418901000688	[86]	[417]	-2	hSpCas9	negative selection	12244221
88065431	88065454	4	+	28162770	OCIAML2	viability	TCAGAGAGTCTGCGGCAAGGAGG	PKD2	ENSG00000118762	0.5962016832360475	[57]	[485]	6	hSpCas9	negative selection	12244222
88065857	88065880	4	+	28162770	OCIAML2	viability	GAGACGACTTGGAGAAAGAGAGG	PKD2	ENSG00000118762	0.7600492072792475	[30]	[290]	7	hSpCas9	negative selection	12244223
88068000	88068023	4	+	28162770	OCIAML2	viability	GGACATAGCTCCAGAAGGAGGGG	PKD2	ENSG00000118762	0.09327105995116525	[22]	[135]	0	hSpCas9	negative selection	12244224
88074901	88074924	4	+	28162770	OCIAML2	viability	AGCGAGCCAAACTGAAGAGGAGG	PKD2	ENSG00000118762	-0.18112320804717635	[26]	[131]	-1	hSpCas9	negative selection	12244225
88007898	88007921	4	+	28162770	OCIAML3	viability	GATGCAGCGCATCCGGCAGGCGG	PKD2	ENSG00000118762	-1.594007640324163	[0]	[0]	-8	hSpCas9	negative selection	12413582
88074932	88074955	4	+	28162770	OCIAML3	viability	GGGAAGGCTGTTGGATGGGGTGG	PKD2	ENSG00000118762	-0.6457226768683185	[70]	[136]	-5	hSpCas9	negative selection	12413583
88007962	88007985	4	-	28162770	OCIAML3	viability	CGGGAGCACGACGAGAGCGGAGG	PKD2	ENSG00000118762	0.33199177823206016	[34]	[132]	3	hSpCas9	negative selection	12413584
88008034	88008057	4	+	28162770	OCIAML3	viability	GAGGAGGTGGAAGGGGAAGAAGG	PKD2	ENSG00000118762	-3.6163754533526173	[64]	[15]	-9	hSpCas9	negative selection	12413585
88043317	88043340	4	+	28162770	OCIAML3	viability	GGATTTGTCAAGAACAAGAGAGG	PKD2	ENSG00000118762	-0.00904513960300703	[51]	[155]	0	hSpCas9	negative selection	12413586
88043394	88043417	4	-	28162770	OCIAML3	viability	GAAGTCAATAAAAGTTGCCCTGG	PKD2	ENSG00000118762	0.5588438477592076	[84]	[377]	5	hSpCas9	negative selection	12413587
88065431	88065454	4	+	28162770	OCIAML3	viability	TCAGAGAGTCTGCGGCAAGGAGG	PKD2	ENSG00000118762	-0.2621640765717182	[86]	[218]	-2	hSpCas9	negative selection	12413588
88065857	88065880	4	+	28162770	OCIAML3	viability	GAGACGACTTGGAGAAAGAGAGG	PKD2	ENSG00000118762	-0.0179782643730146	[53]	[160]	0	hSpCas9	negative selection	12413589
88068000	88068023	4	+	28162770	OCIAML3	viability	GGACATAGCTCCAGAAGGAGGGG	PKD2	ENSG00000118762	1.0029275020630688	[39]	[241]	8	hSpCas9	negative selection	12413590
88074901	88074924	4	+	28162770	OCIAML3	viability	AGCGAGCCAAACTGAAGAGGAGG	PKD2	ENSG00000118762	-0.26216407657171814	[28]	[72]	-2	hSpCas9	negative selection	12413591