Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:5728
• Symbol:Pten
• Description:phosphatase and tensin homolog

DataSource: http://genomecrispr.dkfz.de/#!/results/Pten

Export (tab separated) Export to Excel

Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
87931068	87931091	10	+	26472758	Jiyoye	viability	ACCGCCAAATTTAATTGCAGAGG	PTEN	ENSG00000171862	1.2007245040384469	[89]	[155]	7	hSpCas9	negative selection	130568
87933132	87933155	10	+	26472758	Jiyoye	viability	AAAGCTGGAAAGGGACGAACTGG	PTEN	ENSG00000171862	0.1240033301010034	[100]	[82]	0	hSpCas9	negative selection	130569
87957910	87957933	10	-	26472758	Jiyoye	viability	GAACTTGTCTTCCCGTCGTGTGG	PTEN	ENSG00000171862	0.1537270245012775	[179]	[150]	1	hSpCas9	negative selection	130570
87957899	87957922	10	+	26472758	Jiyoye	viability	CAATTCAGGACCCACACGACGGG	PTEN	ENSG00000171862	0.6275654499311735	[205]	[239]	4	hSpCas9	negative selection	130571
87952177	87952200	10	+	26472758	Jiyoye	viability	TCATCTGGATTATAGACCAGTGG	PTEN	ENSG00000171862	0.45123056158380903	[257]	[265]	3	hSpCas9	negative selection	130572
87933045	87933068	10	-	26472758	Jiyoye	viability	GGTTTGATAAGTTCTAGCTGTGG	PTEN	ENSG00000171862	0.14844111310570507	[66]	[55]	1	hSpCas9	negative selection	130573
87961010	87961033	10	+	26472758	Jiyoye	viability	AGAGCGTGCAGATAATGACAAGG	PTEN	ENSG00000171862	-1.5277295902722419	[129]	[33]	-7	hSpCas9	negative selection	130574
87952235	87952258	10	-	26472758	Jiyoye	viability	CAAGTTCCGCCACTGAACATTGG	PTEN	ENSG00000171862	0.00745868151078577	[561]	[425]	0	hSpCas9	negative selection	130575
87864477	87864500	10	-	26472758	Jiyoye	viability	GCTAACGATCTCTTTGATGATGG	PTEN	ENSG00000171862	0.5796425775106389	[188]	[212]	4	hSpCas9	negative selection	130576
87933117	87933140	10	+	26472758	Jiyoye	viability	GCAGCAATTCACTGTAAAGCTGG	PTEN	ENSG00000171862	-0.5257104226355898	[188]	[98]	-4	hSpCas9	negative selection	130577
87931068	87931091	10	+	26472758	KBM7	viability	ACCGCCAAATTTAATTGCAGAGG	PTEN	ENSG00000171862	0.5163090775609805	[285,397]	[329,149]	5	hSpCas9	negative selection	321686
87933132	87933155	10	+	26472758	KBM7	viability	AAAGCTGGAAAGGGACGAACTGG	PTEN	ENSG00000171862	0.10271760089161391	[382,380]	[188,197]	1	hSpCas9	negative selection	321687
87957910	87957933	10	-	26472758	KBM7	viability	GAACTTGTCTTCCCGTCGTGTGG	PTEN	ENSG00000171862	0.9710344757341314	[637,507]	[815,263]	9	hSpCas9	negative selection	321688
87957899	87957922	10	+	26472758	KBM7	viability	CAATTCAGGACCCACACGACGGG	PTEN	ENSG00000171862	0.6649641626843099	[1524,1403]	[1328,880]	7	hSpCas9	negative selection	321689
87952177	87952200	10	+	26472758	KBM7	viability	TCATCTGGATTATAGACCAGTGG	PTEN	ENSG00000171862	-0.09910667529359651	[1294,849]	[583,354]	-1	hSpCas9	negative selection	321690
87933045	87933068	10	-	26472758	KBM7	viability	GGTTTGATAAGTTCTAGCTGTGG	PTEN	ENSG00000171862	-0.734091027467077	[461,144]	[116,49]	-6	hSpCas9	negative selection	321691
87961010	87961033	10	+	26472758	KBM7	viability	AGAGCGTGCAGATAATGACAAGG	PTEN	ENSG00000171862	0.1921410406453246	[313,344]	[136,215]	2	hSpCas9	negative selection	321692
87952235	87952258	10	-	26472758	KBM7	viability	CAAGTTCCGCCACTGAACATTGG	PTEN	ENSG00000171862	-0.05903759908765438	[1738,1709]	[791,771]	0	hSpCas9	negative selection	321693
87864477	87864500	10	-	26472758	KBM7	viability	GCTAACGATCTCTTTGATGATGG	PTEN	ENSG00000171862	0.4560424609069986	[935,979]	[794,467]	5	hSpCas9	negative selection	321694
87933117	87933140	10	+	26472758	KBM7	viability	GCAGCAATTCACTGTAAAGCTGG	PTEN	ENSG00000171862	-0.009809945210308868	[673,603]	[303,292]	0	hSpCas9	negative selection	321695
87931068	87931091	10	+	26472758	Raji	viability	ACCGCCAAATTTAATTGCAGAGG	PTEN	ENSG00000171862	1.6709723853021887	[271]	[200]	9	hSpCas9	negative selection	512804
87933132	87933155	10	+	26472758	Raji	viability	AAAGCTGGAAAGGGACGAACTGG	PTEN	ENSG00000171862	2.1513268829611967	[96]	[99]	9	hSpCas9	negative selection	512805
87957910	87957933	10	-	26472758	Raji	viability	GAACTTGTCTTCCCGTCGTGTGG	PTEN	ENSG00000171862	1.0474014305453672	[220]	[105]	8	hSpCas9	negative selection	512806
87957899	87957922	10	+	26472758	Raji	viability	CAATTCAGGACCCACACGACGGG	PTEN	ENSG00000171862	1.362173947112485	[584]	[348]	9	hSpCas9	negative selection	512807
87952177	87952200	10	+	26472758	Raji	viability	TCATCTGGATTATAGACCAGTGG	PTEN	ENSG00000171862	1.1987063202910664	[504]	[268]	9	hSpCas9	negative selection	512808
87933045	87933068	10	-	26472758	Raji	viability	GGTTTGATAAGTTCTAGCTGTGG	PTEN	ENSG00000171862	-0.1405439780699862	[132]	[27]	-1	hSpCas9	negative selection	512809
87961010	87961033	10	+	26472758	Raji	viability	AGAGCGTGCAGATAATGACAAGG	PTEN	ENSG00000171862	-0.3780432917966424	[167]	[29]	-3	hSpCas9	negative selection	512810
87952235	87952258	10	-	26472758	Raji	viability	CAAGTTCCGCCACTGAACATTGG	PTEN	ENSG00000171862	0.9530967927918303	[1123]	[504]	8	hSpCas9	negative selection	512811
87864477	87864500	10	-	26472758	Raji	viability	GCTAACGATCTCTTTGATGATGG	PTEN	ENSG00000171862	1.303713660123851	[390]	[223]	9	hSpCas9	negative selection	512812
87933117	87933140	10	+	26472758	Raji	viability	GCAGCAATTCACTGTAAAGCTGG	PTEN	ENSG00000171862	1.2260280318722183	[244]	[132]	9	hSpCas9	negative selection	512813
87931068	87931091	10	+	26472758	K562	viability	ACCGCCAAATTTAATTGCAGAGG	PTEN	ENSG00000171862	0.4814579249672963	[363]	[428]	4	hSpCas9	negative selection	703922
87933132	87933155	10	+	26472758	K562	viability	AAAGCTGGAAAGGGACGAACTGG	PTEN	ENSG00000171862	-2.231314703299951	[266]	[47]	-7	hSpCas9	negative selection	703923
87957910	87957933	10	-	26472758	K562	viability	GAACTTGTCTTCCCGTCGTGTGG	PTEN	ENSG00000171862	-0.6436883922626558	[495]	[267]	-4	hSpCas9	negative selection	703924
87957899	87957922	10	+	26472758	K562	viability	CAATTCAGGACCCACACGACGGG	PTEN	ENSG00000171862	-1.5705027941183007	[1146]	[325]	-7	hSpCas9	negative selection	703925
87952177	87952200	10	+	26472758	K562	viability	TCATCTGGATTATAGACCAGTGG	PTEN	ENSG00000171862	-1.1657553596933572	[690]	[259]	-6	hSpCas9	negative selection	703926
87933045	87933068	10	-	26472758	K562	viability	GGTTTGATAAGTTCTAGCTGTGG	PTEN	ENSG00000171862	-2.5856562708912407	[255]	[35]	-8	hSpCas9	negative selection	703927
87961010	87961033	10	+	26472758	K562	viability	AGAGCGTGCAGATAATGACAAGG	PTEN	ENSG00000171862	-2.593830202336941	[235]	[32]	-8	hSpCas9	negative selection	703928
87952235	87952258	10	-	26472758	K562	viability	CAAGTTCCGCCACTGAACATTGG	PTEN	ENSG00000171862	-1.3395288626780744	[1420]	[473]	-6	hSpCas9	negative selection	703929
87864477	87864500	10	-	26472758	K562	viability	GCTAACGATCTCTTTGATGATGG	PTEN	ENSG00000171862	-0.9159519670626167	[902]	[403]	-5	hSpCas9	negative selection	703930
87933117	87933140	10	+	26472758	K562	viability	GCAGCAATTCACTGTAAAGCTGG	PTEN	ENSG00000171862	-1.12207491965436	[525]	[203]	-6	hSpCas9	negative selection	703931
87863546	87863569	10	-	25494202	A375	resistance to PLX-4720 (puromycin)	CCCGCCACATCACCGCCCGCCGG	PTEN	ENSG00000171862	-0.9228404249595894	[35,32]	[3,2]	-5	dCas9-VP64	positive selection	2397312
87863580	87863603	10	+	25494202	A375	resistance to PLX-4720 (puromycin)	GCTGCGGCAGGATACGCGCTCGG	PTEN	ENSG00000171862	0.2859704055171742	[5,111]	[2,28]	1	dCas9-VP64	positive selection	2397313
87863527	87863550	10	+	25494202	A375	resistance to PLX-4720 (puromycin)	GGCGGAGGGGGCGGGCAGGCCGG	PTEN	ENSG00000171862	-2.583020045914306	[53,0]	[0,0]	-9	dCas9-VP64	positive selection	2397314
87878082	87878105	10	+	25494202	A375	resistance to PLX-4720 (puromycin)	TTTTTTTTTGAGACGGAGTCTAG	PTEN	ENSG00000171862	-0.0033727294007129816	[93,134]	[41,5]	0	dCas9-VP64	positive selection	2412602
87921467	87921490	10	-	25494202	A375	resistance to PLX-4720 (puromycin)	CGAGACTAGCCTGGCCAACACAG	PTEN	ENSG00000171862	0.3601150748164519	[269,268]	[95,53]	1	dCas9-VP64	positive selection	2458909
87964331	87964354	10	-	25494202	A375	resistance to PLX-4720 (puromycin)	CAGGCTGGTCTCAAACTCCTTAG	PTEN	ENSG00000171862	1.754298476960665	[131,229]	[162,104]	6	dCas9-VP64	positive selection	2469876
87863546	87863569	10	-	25494202	A375	resistance to PLX-4720 (zeocin)	CCCGCCACATCACCGCCCGCCGG	PTEN	ENSG00000171862	1.3787531034518568	[80,93]	[100,49]	7	dCas9-VP64	positive selection	2492567
87863580	87863603	10	+	25494202	A375	resistance to PLX-4720 (zeocin)	GCTGCGGCAGGATACGCGCTCGG	PTEN	ENSG00000171862	-0.6594777977323185	[28,66]	[10,7]	-6	dCas9-VP64	positive selection	2492568
87863527	87863550	10	+	25494202	A375	resistance to PLX-4720 (zeocin)	GGCGGAGGGGGCGGGCAGGCCGG	PTEN	ENSG00000171862	-1.7641557787710018	[1,106]	[1,6]	-9	dCas9-VP64	positive selection	2492569
87878082	87878105	10	+	25494202	A375	resistance to PLX-4720 (zeocin)	TTTTTTTTTGAGACGGAGTCTAG	PTEN	ENSG00000171862	-0.5948176551250917	[72,353]	[48,41]	-6	dCas9-VP64	positive selection	2507857
87921467	87921490	10	-	25494202	A375	resistance to PLX-4720 (zeocin)	CGAGACTAGCCTGGCCAACACAG	PTEN	ENSG00000171862	-0.8374586120276372	[108,300]	[27,44]	-7	dCas9-VP64	positive selection	2554164
87964331	87964354	10	-	25494202	A375	resistance to PLX-4720 (zeocin)	CAGGCTGGTCTCAAACTCCTTAG	PTEN	ENSG00000171862	0.3544513964898359	[322,573]	[129,237]	3	dCas9-VP64	positive selection	2565131
87931069	87931092	10	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	ACCTCTGCAATTAAATTTGGCGG	PTEN	ENSG00000171862	0.6817037574705394	[4,4]	[7,6]	9	hSpCas9	positive selection	3014538
87933207	87933230	10	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	AGAGGCCCTAGATTTCTATGGGG	PTEN	ENSG00000171862	-0.018537817266100903	[4,4]	[4,2]	0	hSpCas9	positive selection	3014539
87952120	87952143	10	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GAGTAACTATTCCCAGTCAGAGG	PTEN	ENSG00000171862	0.05471353149285951	[5,5]	[6,3]	1	hSpCas9	positive selection	3014540
87933024	87933047	10	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GGTGGGTTATGGTCTTCAAAAGG	PTEN	ENSG00000171862	-0.10325320869024257	[2,3]	[4,0]	-1	hSpCas9	positive selection	3014541
87931069	87931092	10	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	ACCTCTGCAATTAAATTTGGCGG	PTEN	ENSG00000171862	-0.05495313286769199	[4,4]	[6,0]	-1	hSpCas9	positive selection	3082396
87933207	87933230	10	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	AGAGGCCCTAGATTTCTATGGGG	PTEN	ENSG00000171862	0.8603659129185626	[4,4]	[5,5]	9	hSpCas9	positive selection	3082397
87952120	87952143	10	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GAGTAACTATTCCCAGTCAGAGG	PTEN	ENSG00000171862	0.741764936031766	[5,5]	[6,6]	9	hSpCas9	positive selection	3082398
87933024	87933047	10	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GGTGGGTTATGGTCTTCAAAAGG	PTEN	ENSG00000171862	0.30099886590310787	[2,2]	[2,2]	5	hSpCas9	positive selection	3082399
87931068	87931091		+	24336571	A375	resistance to PLX after 7 days	ACCGCCAAATTTAATTGCAGAGG	PTEN	ENSG00000171862	0.3211811011011002	[4,4]	[4,6]	8	hSpCas9	positive selection	3138618
87931072	87931095		-	24336571	A375	resistance to PLX after 7 days	CCTACCTCTGCAATTAAATTTGG	PTEN	ENSG00000171862	0.021639491861625948	[6,6]	[6,5]	0	hSpCas9	positive selection	3138619
87894029	87894052		+	24336571	A375	resistance to PLX after 7 days	TTATCCAAACATTATTGCTATGG	PTEN	ENSG00000171862	0.19479442056092555	[5,5]	[6,6]	6	hSpCas9	positive selection	3138621
87931068	87931091		+	24336571	A375	resistance to PLX after 14 days	ACCGCCAAATTTAATTGCAGAGG	PTEN	ENSG00000171862	-0.010364019979827721	[6,6]	[2,1]	0	hSpCas9	positive selection	3196411
87931072	87931095		-	24336571	A375	resistance to PLX after 14 days	CCTACCTCTGCAATTAAATTTGG	PTEN	ENSG00000171862	-0.39264271260229255	[6,9]	[2,1]	-5	hSpCas9	positive selection	3196412
87894029	87894052		+	24336571	A375	resistance to PLX after 14 days	TTATCCAAACATTATTGCTATGG	PTEN	ENSG00000171862	0.8892415102286287	[7,5]	[4,6]	7	hSpCas9	positive selection	3196414
87931068	87931091		+	24336571	A375	viability after 7 days	ACCGCCAAATTTAATTGCAGAGG	PTEN	ENSG00000171862	-0.2452202149754814	[5]	[4,4]	-3	hSpCas9	negative selection	3254204
87931072	87931095		-	24336571	A375	viability after 7 days	CCTACCTCTGCAATTAAATTTGG	PTEN	ENSG00000171862	-1.068689626433629	[14]	[6,6]	-9	hSpCas9	negative selection	3254205
87894029	87894052		+	24336571	A375	viability after 7 days	TTATCCAAACATTATTGCTATGG	PTEN	ENSG00000171862	-0.5252631193120724	[8]	[5,5]	-6	hSpCas9	negative selection	3254207
87931068	87931091		+	24336571	A375	viability after 14 days	ACCGCCAAATTTAATTGCAGAGG	PTEN	ENSG00000171862	0.1791409670684022	[5]	[6,6]	2	hSpCas9	negative selection	3311997
87931072	87931095		-	24336571	A375	viability after 14 days	CCTACCTCTGCAATTAAATTTGG	PTEN	ENSG00000171862	-0.7756282876364817	[14]	[6,9]	-7	hSpCas9	negative selection	3311998
87894029	87894052		+	24336571	A375	viability after 14 days	TTATCCAAACATTATTGCTATGG	PTEN	ENSG00000171862	-0.2750961689158863	[8]	[7,5]	-3	hSpCas9	negative selection	3312000
87925537	87925560	10	-	27383988	293T	resistance to West Nile virus (flavivirus)	ACAGATTGTATATCTTGTAATGG	PTEN	ENSG00000171862	0.7815927804794374	[88,88]	[0,0]	4	hSpCas9	positive selection	3388140
87894057	87894080	10	-	27383988	293T	resistance to West Nile virus (flavivirus)	ACGCCTTCAAGTCTTTCTGCAGG	PTEN	ENSG00000171862	5.441038164618224	[161,161]	[45,45]	9	hSpCas9	positive selection	3388141
87965431	87965454	10	-	27383988	293T	resistance to West Nile virus (flavivirus)	GTATGCTGATCTTCATCAAAAGG	PTEN	ENSG00000171862	-0.2425196756373702	[180,180]	[0,0]	-1	hSpCas9	positive selection	3388142
87931069	87931092	10	-	26780180	HT29	viability (Avana library 4 designs)	ACCTCTGCAATTAAATTTGGCGG	PTEN	ENSG00000171862	-2.99838174830351	[]	[]	-9	hSpCas9	negative selection	3452778
87933206	87933229	10	+	26780180	HT29	viability (Avana library 4 designs)	AGAGGCCCTAGATTTCTATGGGG	PTEN	ENSG00000171862	-3.02525531185284	[]	[]	-9	hSpCas9	negative selection	3452779
87952119	87952142	10	+	26780180	HT29	viability (Avana library 4 designs)	GAGTAACTATTCCCAGTCAGAGG	PTEN	ENSG00000171862	-3.14538500547593	[]	[]	-9	hSpCas9	negative selection	3452780
87933024	87933047	10	-	26780180	HT29	viability (Avana library 4 designs)	GGTGGGTTATGGTCTTCAAAAGG	PTEN	ENSG00000171862	0.0222193050308656	[]	[]	0	hSpCas9	negative selection	3452781
87933206	87933229	10	+	26780180	A375	viability (Avana lentiCRISPRv2)	AGAGGCCCTAGATTTCTATGGGG	PTEN	ENSG00000171862	7.06630615842261	[]	[]	9	hSpCas9	negative selection	3549312
87952119	87952142	10	+	26780180	A375	viability (Avana lentiCRISPRv2)	GAGTAACTATTCCCAGTCAGAGG	PTEN	ENSG00000171862	7.71380248098276	[]	[]	9	hSpCas9	negative selection	3549313
87933024	87933047	10	-	26780180	A375	viability (Avana lentiCRISPRv2)	GGTGGGTTATGGTCTTCAAAAGG	PTEN	ENSG00000171862	5.82453701915217	[]	[]	9	hSpCas9	negative selection	3549314
87931069	87931092	10	-	26780180	A375	viability (Avana lentiCRISPRv2)	ACCTCTGCAATTAAATTTGGCGG	PTEN	ENSG00000171862	0.28966974674544	[]	[]	0	hSpCas9	negative selection	3549315
87952177	87952200	10	+	26780180	A375	viability (Avana lentiCRISPRv2)	TCATCTGGATTATAGACCAGTGG	PTEN	ENSG00000171862	7.10880826502717	[]	[]	9	hSpCas9	negative selection	3549316
87933066	87933089	10	-	26780180	A375	viability (Avana lentiCRISPRv2)	TGGTCAAGATCTTCACAAAAGGG	PTEN	ENSG00000171862	-6.30639410681653	[]	[]	-6	hSpCas9	negative selection	3549317
87933206	87933229	10	+	26780180	A375	viability (Avana lentiGuide)	AGAGGCCCTAGATTTCTATGGGG	PTEN	ENSG00000171862	-9.05184855534218	[]	[]	-9	hSpCas9	negative selection	3657971
87952119	87952142	10	+	26780180	A375	viability (Avana lentiGuide)	GAGTAACTATTCCCAGTCAGAGG	PTEN	ENSG00000171862	-9.04986446648381	[]	[]	-9	hSpCas9	negative selection	3657972
87933024	87933047	10	-	26780180	A375	viability (Avana lentiGuide)	GGTGGGTTATGGTCTTCAAAAGG	PTEN	ENSG00000171862	-6.74767597520604	[]	[]	-9	hSpCas9	negative selection	3657973
87931069	87931092	10	-	26780180	A375	viability (Avana lentiGuide)	ACCTCTGCAATTAAATTTGGCGG	PTEN	ENSG00000171862	-7.75582213389132	[]	[]	-9	hSpCas9	negative selection	3657974
87952177	87952200	10	+	26780180	A375	viability (Avana lentiGuide)	TCATCTGGATTATAGACCAGTGG	PTEN	ENSG00000171862	-5.51274729308284	[]	[]	-8	hSpCas9	negative selection	3657975
87933066	87933089	10	-	26780180	A375	viability (Avana lentiGuide)	TGGTCAAGATCTTCACAAAAGGG	PTEN	ENSG00000171862	-13.5205468071931	[]	[]	-9	hSpCas9	negative selection	3657976
87933206	87933229	10	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AGAGGCCCTAGATTTCTATGGGG	PTEN	ENSG00000171862	0.4825447898096391	[5]	[8,7]	9	hSpCas9	positive selection	3766578
87952119	87952142	10	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GAGTAACTATTCCCAGTCAGAGG	PTEN	ENSG00000171862	0.48655695036262947	[6]	[9,7]	9	hSpCas9	positive selection	3766579
87933024	87933047	10	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGTGGGTTATGGTCTTCAAAAGG	PTEN	ENSG00000171862	0.1213367283052942	[4]	[5,4]	3	hSpCas9	positive selection	3766580
87931069	87931092	10	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ACCTCTGCAATTAAATTTGGCGG	PTEN	ENSG00000171862	0.2732233090652738	[5]	[6,6]	7	hSpCas9	positive selection	3766581
87952177	87952200	10	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TCATCTGGATTATAGACCAGTGG	PTEN	ENSG00000171862	0.48182923918468007	[4]	[7,6]	9	hSpCas9	positive selection	3766582
87933066	87933089	10	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TGGTCAAGATCTTCACAAAAGGG	PTEN	ENSG00000171862	-0.3660347272596423	[6]	[5,4]	-5	hSpCas9	positive selection	3766583
87933206	87933229	10	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AGAGGCCCTAGATTTCTATGGGG	PTEN	ENSG00000171862	0.5113961788613055	[5]	[6,7]	9	hSpCas9	positive selection	3875185
87952119	87952142	10	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GAGTAACTATTCCCAGTCAGAGG	PTEN	ENSG00000171862	0.466992284750466	[6]	[8,7]	9	hSpCas9	positive selection	3875186
87933024	87933047	10	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGTGGGTTATGGTCTTCAAAAGG	PTEN	ENSG00000171862	0.04247746699897653	[4]	[2,5]	0	hSpCas9	positive selection	3875187
87931069	87931092	10	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ACCTCTGCAATTAAATTTGGCGG	PTEN	ENSG00000171862	0.7022501602956311	[5]	[8,7]	9	hSpCas9	positive selection	3875188
87952177	87952200	10	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TCATCTGGATTATAGACCAGTGG	PTEN	ENSG00000171862	0.6825280404573553	[4]	[6,6]	9	hSpCas9	positive selection	3875189
87933066	87933089	10	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TGGTCAAGATCTTCACAAAAGGG	PTEN	ENSG00000171862	0.5739810623809853	[5]	[6,6]	9	hSpCas9	positive selection	3875190
87925537	87925560	10	-	26780180	A375	viability	ACAGATTGTATATCTTGTAATGG	PTEN	ENSG00000171862	0.226055102963906	[]	[]	0	hSpCas9	negative selection	3985622
87931068	87931091	10	+	26780180	A375	viability	ACCGCCAAATTTAATTGCAGAGG	PTEN	ENSG00000171862	-0.451838840341533	[]	[]	-9	hSpCas9	negative selection	3985623
87931072	87931095	10	-	26780180	A375	viability	CCTACCTCTGCAATTAAATTTGG	PTEN	ENSG00000171862	0.907763247175804	[]	[]	4	hSpCas9	negative selection	3985624
87894029	87894052	10	+	26780180	A375	viability	TTATCCAAACATTATTGCTATGG	PTEN	ENSG00000171862	0.378737086970662	[]	[]	0	hSpCas9	negative selection	3985625
87925537	87925560	10	-	26780180	HT29	viability (GeCKOv2 library)	ACAGATTGTATATCTTGTAATGG	PTEN	ENSG00000171862	1.11886345131034	[]	[]	5	hSpCas9	negative selection	4093588
87931068	87931091	10	+	26780180	HT29	viability (GeCKOv2 library)	ACCGCCAAATTTAATTGCAGAGG	PTEN	ENSG00000171862	-0.481741386014445	[]	[]	-9	hSpCas9	negative selection	4093589
87931072	87931095	10	-	26780180	HT29	viability (GeCKOv2 library)	CCTACCTCTGCAATTAAATTTGG	PTEN	ENSG00000171862	0.657195354520764	[]	[]	2	hSpCas9	negative selection	4093590
87894029	87894052	10	+	26780180	HT29	viability (GeCKOv2 library)	TTATCCAAACATTATTGCTATGG	PTEN	ENSG00000171862	0.457879554523294	[]	[]	1	hSpCas9	negative selection	4093591
87931068	87931091	10	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	ACCGCCAAATTTAATTGCAGAGG	PTEN	ENSG00000171862	-0.06646214894304209	[2]	[1,1]	-1	hSpCas9	positive selection	4163872
87931072	87931095	10	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CCTACCTCTGCAATTAAATTTGG	PTEN	ENSG00000171862	0.09494577886406819	[2]	[2,1]	2	hSpCas9	positive selection	4163873
87894029	87894052	10	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TTATCCAAACATTATTGCTATGG	PTEN	ENSG00000171862	0.2558432205613965	[2]	[1,2]	6	hSpCas9	positive selection	4163875
87931068	87931091	10	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	ACCGCCAAATTTAATTGCAGAGG	PTEN	ENSG00000171862	-0.023780021784472805	[2]	[0,0,1,0]	0	hSpCas9	positive selection	4227894
87931072	87931095	10	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CCTACCTCTGCAATTAAATTTGG	PTEN	ENSG00000171862	0.31115554548873187	[3]	[0,2,4,0]	2	hSpCas9	positive selection	4227895
87894029	87894052	10	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TTATCCAAACATTATTGCTATGG	PTEN	ENSG00000171862	-0.029938131032810723	[3]	[3,1,1,0]	0	hSpCas9	positive selection	4227897
87931068	87931091	10	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ACCGCCAAATTTAATTGCAGAGG	PTEN	ENSG00000171862	1.0030850865728302	[2]	[4,4]	9	hSpCas9	positive selection	4292927
87931072	87931095	10	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCTACCTCTGCAATTAAATTTGG	PTEN	ENSG00000171862	0.23681607795653187	[1]	[2,0]	5	hSpCas9	positive selection	4292928
87894029	87894052	10	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TTATCCAAACATTATTGCTATGG	PTEN	ENSG00000171862	0.09053724321812542	[2]	[3,0]	1	hSpCas9	positive selection	4292929
87925537	87925560	10	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ACAGATTGTATATCTTGTAATGG	PTEN	ENSG00000171862	0.16381702743163173	[2]	[2,1]	3	hSpCas9	positive selection	4357186
87894065	87894087	10	+	27760321	OCIAML3	viability	AAGACTTGAAGGCGTATACAGG	PTEN	ENSG00000171862	0.349869932207314	[0,0]	[0,0]	4	hSpCas9	negative selection	4431678
87931069	87931091	10	+	27760321	OCIAML3	viability	CCGCCAAATTTAATTGCAGAGG	PTEN	ENSG00000171862	1.2494706577326202	[354,289]	[475,753]	9	hSpCas9	negative selection	4431679
87933041	87933063	10	-	27760321	OCIAML3	viability	GATAAGTTCTAGCTGTGGTGGG	PTEN	ENSG00000171862	0.5479394678752458	[594,534]	[551,766]	6	hSpCas9	negative selection	4431680
87952114	87952136	10	-	27760321	OCIAML3	viability	ACTGGGAATAGTTACTCCCTGG	PTEN	ENSG00000171862	0.5983160274283398	[206,163]	[196,245]	7	hSpCas9	negative selection	4431681
87952165	87952187	10	-	27760321	OCIAML3	viability	ATCCAGATGATTCTTTAACAGG	PTEN	ENSG00000171862	-1.1220080545667495	[56,44]	[12,24]	-7	hSpCas9	negative selection	4431682
87894065	87894087	10	+	27760321	OCIAML2	viability	AAGACTTGAAGGCGTATACAGG	PTEN	ENSG00000171862	0.3011245669422653	[0,0]	[0,0]	4	hSpCas9	negative selection	4515141
87931069	87931091	10	+	27760321	OCIAML2	viability	CCGCCAAATTTAATTGCAGAGG	PTEN	ENSG00000171862	1.3298993602376386	[354,289]	[548,788]	9	hSpCas9	negative selection	4515142
87933041	87933063	10	-	27760321	OCIAML2	viability	GATAAGTTCTAGCTGTGGTGGG	PTEN	ENSG00000171862	1.6959519190065402	[594,534]	[1171,1883]	9	hSpCas9	negative selection	4515143
87952114	87952136	10	-	27760321	OCIAML2	viability	ACTGGGAATAGTTACTCCCTGG	PTEN	ENSG00000171862	1.857009606898307	[206,163]	[465,637]	9	hSpCas9	negative selection	4515144
87952165	87952187	10	-	27760321	OCIAML2	viability	ATCCAGATGATTCTTTAACAGG	PTEN	ENSG00000171862	2.232471574419943	[56,44]	[139,261]	9	hSpCas9	negative selection	4515145
87894065	87894087	10	+	27760321	MV411	viability	AAGACTTGAAGGCGTATACAGG	PTEN	ENSG00000171862	0.5949485011219959	[0,0]	[0,0]	4	hSpCas9	negative selection	4598604
87931069	87931091	10	+	27760321	MV411	viability	CCGCCAAATTTAATTGCAGAGG	PTEN	ENSG00000171862	0.25788465685631196	[354,289]	[255,248]	1	hSpCas9	negative selection	4598605
87933041	87933063	10	-	27760321	MV411	viability	GATAAGTTCTAGCTGTGGTGGG	PTEN	ENSG00000171862	-0.5670193919784206	[594,534]	[254,245]	-4	hSpCas9	negative selection	4598606
87952114	87952136	10	-	27760321	MV411	viability	ACTGGGAATAGTTACTCCCTGG	PTEN	ENSG00000171862	3.470616906616716	[206,163]	[2015,345]	9	hSpCas9	negative selection	4598607
87952165	87952187	10	-	27760321	MV411	viability	ATCCAGATGATTCTTTAACAGG	PTEN	ENSG00000171862	-5.063522669334737	[56,44]	[0,0]	-9	hSpCas9	negative selection	4598608
87894065	87894087	10	+	27760321	HL60	viability	AAGACTTGAAGGCGTATACAGG	PTEN	ENSG00000171862	0.2870783393278593	[0,0]	[0,0]	3	hSpCas9	negative selection	4682067
87931069	87931091	10	+	27760321	HL60	viability	CCGCCAAATTTAATTGCAGAGG	PTEN	ENSG00000171862	2.680080851296762	[354,289]	[1628,1733]	9	hSpCas9	negative selection	4682068
87933041	87933063	10	-	27760321	HL60	viability	GATAAGTTCTAGCTGTGGTGGG	PTEN	ENSG00000171862	1.6016613890386617	[594,534]	[1737,1039]	9	hSpCas9	negative selection	4682069
87952114	87952136	10	-	27760321	HL60	viability	ACTGGGAATAGTTACTCCCTGG	PTEN	ENSG00000171862	1.26709502172205	[206,163]	[475,241]	9	hSpCas9	negative selection	4682070
87952165	87952187	10	-	27760321	HL60	viability	ATCCAGATGATTCTTTAACAGG	PTEN	ENSG00000171862	3.2093663812883095	[56,44]	[378,386]	9	hSpCas9	negative selection	4682071
87894065	87894087	10	+	27760321	HT1080	viability	AAGACTTGAAGGCGTATACAGG	PTEN	ENSG00000171862	1.3056276939190559	[0,0]	[0,0]	7	hSpCas9	negative selection	4765530
87931069	87931091	10	+	27760321	HT1080	viability	CCGCCAAATTTAATTGCAGAGG	PTEN	ENSG00000171862	2.236421734360546	[289,226]	[555,407]	9	hSpCas9	negative selection	4765531
87933041	87933063	10	-	27760321	HT1080	viability	GATAAGTTCTAGCTGTGGTGGG	PTEN	ENSG00000171862	0.7196874258599333	[534,417]	[230,401]	4	hSpCas9	negative selection	4765532
87952114	87952136	10	-	27760321	HT1080	viability	ACTGGGAATAGTTACTCCCTGG	PTEN	ENSG00000171862	1.6522604659202156	[163,127]	[315,36]	8	hSpCas9	negative selection	4765533
87952165	87952187	10	-	27760321	HT1080	viability	ATCCAGATGATTCTTTAACAGG	PTEN	ENSG00000171862	-3.9938032550165907	[44,34]	[0,0]	-8	hSpCas9	negative selection	4765534
87894065	87894087	10	+	27760321	HT29	viability after 7 days	AAGACTTGAAGGCGTATACAGG	PTEN	ENSG00000171862	-0.3840325596302083	[0,0]	[0,0,0]	-5	hSpCas9	negative selection	4848993
87931069	87931091	10	+	27760321	HT29	viability after 7 days	CCGCCAAATTTAATTGCAGAGG	PTEN	ENSG00000171862	0.8524017054662806	[289,226]	[678,629,504]	9	hSpCas9	negative selection	4848994
87933041	87933063	10	-	27760321	HT29	viability after 7 days	GATAAGTTCTAGCTGTGGTGGG	PTEN	ENSG00000171862	0.20114924529984735	[534,417]	[657,856,593]	3	hSpCas9	negative selection	4848995
87952114	87952136	10	-	27760321	HT29	viability after 7 days	ACTGGGAATAGTTACTCCCTGG	PTEN	ENSG00000171862	1.3052739515959464	[163,127]	[631,509,278]	9	hSpCas9	negative selection	4848996
87952165	87952187	10	-	27760321	HT29	viability after 7 days	ATCCAGATGATTCTTTAACAGG	PTEN	ENSG00000171862	-0.21853460230866073	[44,34]	[16,110,1]	-3	hSpCas9	negative selection	4848997
87894065	87894087	10	+	27760321	HT29	viability after 25 days	AAGACTTGAAGGCGTATACAGG	PTEN	ENSG00000171862	-0.21405457092746794	[0,0]	[0,0,0]	-2	hSpCas9	negative selection	4932456
87931069	87931091	10	+	27760321	HT29	viability after 25 days	CCGCCAAATTTAATTGCAGAGG	PTEN	ENSG00000171862	3.2999828429949774	[289,226]	[2830,2868,3044]	9	hSpCas9	negative selection	4932457
87933041	87933063	10	-	27760321	HT29	viability after 25 days	GATAAGTTCTAGCTGTGGTGGG	PTEN	ENSG00000171862	2.785264801854469	[534,417]	[2980,3593,4843]	9	hSpCas9	negative selection	4932458
87952114	87952136	10	-	27760321	HT29	viability after 25 days	ACTGGGAATAGTTACTCCCTGG	PTEN	ENSG00000171862	3.7717381707584163	[163,127]	[2429,1993,2413]	9	hSpCas9	negative selection	4932459
87952165	87952187	10	-	27760321	HT29	viability after 25 days	ATCCAGATGATTCTTTAACAGG	PTEN	ENSG00000171862	2.401202608689882	[44,34]	[126,423,172]	9	hSpCas9	negative selection	4932460
87894065	87894087	10	+	27760321	HT29	viability after 22 days	AAGACTTGAAGGCGTATACAGG	PTEN	ENSG00000171862	-0.23137320278672746	[0,0]	[0,0,0]	-2	hSpCas9	negative selection	5015919
87931069	87931091	10	+	27760321	HT29	viability after 22 days	CCGCCAAATTTAATTGCAGAGG	PTEN	ENSG00000171862	3.0436525823108047	[289,226]	[2057,2849,2496]	9	hSpCas9	negative selection	5015920
87933041	87933063	10	-	27760321	HT29	viability after 22 days	GATAAGTTCTAGCTGTGGTGGG	PTEN	ENSG00000171862	2.304544924873257	[534,417]	[2380,2395,3402]	9	hSpCas9	negative selection	5015921
87952114	87952136	10	-	27760321	HT29	viability after 22 days	ACTGGGAATAGTTACTCCCTGG	PTEN	ENSG00000171862	3.5073121972126327	[163,127]	[1719,2031,2011]	9	hSpCas9	negative selection	5015922
87952165	87952187	10	-	27760321	HT29	viability after 22 days	ATCCAGATGATTCTTTAACAGG	PTEN	ENSG00000171862	1.5884052071381196	[44,34]	[49,280,87]	9	hSpCas9	negative selection	5015923
87894065	87894087	10	+	27760321	HT29	viability after 19 days	AAGACTTGAAGGCGTATACAGG	PTEN	ENSG00000171862	-0.21553315036351428	[0,0]	[0,0,0]	-2	hSpCas9	negative selection	5099382
87931069	87931091	10	+	27760321	HT29	viability after 19 days	CCGCCAAATTTAATTGCAGAGG	PTEN	ENSG00000171862	2.820109771712514	[289,226]	[1930,2901,1438]	9	hSpCas9	negative selection	5099383
87933041	87933063	10	-	27760321	HT29	viability after 19 days	GATAAGTTCTAGCTGTGGTGGG	PTEN	ENSG00000171862	2.0948904041328937	[534,417]	[2342,2083,2548]	9	hSpCas9	negative selection	5099384
87952114	87952136	10	-	27760321	HT29	viability after 19 days	ACTGGGAATAGTTACTCCCTGG	PTEN	ENSG00000171862	3.2053688373858176	[163,127]	[1709,1862,1081]	9	hSpCas9	negative selection	5099385
87952165	87952187	10	-	27760321	HT29	viability after 19 days	ATCCAGATGATTCTTTAACAGG	PTEN	ENSG00000171862	2.854849374625871	[44,34]	[141,321,501]	9	hSpCas9	negative selection	5099386
87894065	87894087	10	+	27760321	HT29	viability after 16 days	AAGACTTGAAGGCGTATACAGG	PTEN	ENSG00000171862	-0.1840686979425925	[0,0]	[0,0,0]	-2	hSpCas9	negative selection	5182845
87931069	87931091	10	+	27760321	HT29	viability after 16 days	CCGCCAAATTTAATTGCAGAGG	PTEN	ENSG00000171862	2.2790071882570904	[289,226]	[1390,1377,1441]	9	hSpCas9	negative selection	5182846
87933041	87933063	10	-	27760321	HT29	viability after 16 days	GATAAGTTCTAGCTGTGGTGGG	PTEN	ENSG00000171862	1.5783627180863338	[534,417]	[1522,1845,1393]	9	hSpCas9	negative selection	5182847
87952114	87952136	10	-	27760321	HT29	viability after 16 days	ACTGGGAATAGTTACTCCCTGG	PTEN	ENSG00000171862	2.766878416472526	[163,127]	[897,1340,1069]	9	hSpCas9	negative selection	5182848
87952165	87952187	10	-	27760321	HT29	viability after 16 days	ATCCAGATGATTCTTTAACAGG	PTEN	ENSG00000171862	1.6195633021149043	[44,34]	[211,193,11]	9	hSpCas9	negative selection	5182849
87894065	87894087	10	+	27760321	HT29	viability after 13 days	AAGACTTGAAGGCGTATACAGG	PTEN	ENSG00000171862	-0.23635609738673047	[0,0]	[0,0,0]	-3	hSpCas9	negative selection	5266308
87931069	87931091	10	+	27760321	HT29	viability after 13 days	CCGCCAAATTTAATTGCAGAGG	PTEN	ENSG00000171862	1.7686815418584376	[289,226]	[1025,1087,955]	9	hSpCas9	negative selection	5266309
87933041	87933063	10	-	27760321	HT29	viability after 13 days	GATAAGTTCTAGCTGTGGTGGG	PTEN	ENSG00000171862	0.9568788491237974	[534,417]	[881,1118,1209]	9	hSpCas9	negative selection	5266310
87952114	87952136	10	-	27760321	HT29	viability after 13 days	ACTGGGAATAGTTACTCCCTGG	PTEN	ENSG00000171862	2.048990668244012	[163,127]	[677,746,678]	9	hSpCas9	negative selection	5266311
87952165	87952187	10	-	27760321	HT29	viability after 13 days	ATCCAGATGATTCTTTAACAGG	PTEN	ENSG00000171862	1.7992332556179458	[44,34]	[327,79,80]	9	hSpCas9	negative selection	5266312
87894065	87894087	10	+	27760321	HT29	viability after 10 days	AAGACTTGAAGGCGTATACAGG	PTEN	ENSG00000171862	-0.34236740454707437	[0,0]	[0,0,0]	-4	hSpCas9	negative selection	5349771
87931069	87931091	10	+	27760321	HT29	viability after 10 days	CCGCCAAATTTAATTGCAGAGG	PTEN	ENSG00000171862	1.2774844158771592	[289,226]	[786,990,579]	9	hSpCas9	negative selection	5349772
87933041	87933063	10	-	27760321	HT29	viability after 10 days	GATAAGTTCTAGCTGTGGTGGG	PTEN	ENSG00000171862	0.9121708711577319	[534,417]	[1054,1131,1170]	9	hSpCas9	negative selection	5349773
87952114	87952136	10	-	27760321	HT29	viability after 10 days	ACTGGGAATAGTTACTCCCTGG	PTEN	ENSG00000171862	1.7812343670540511	[163,127]	[424,764,691]	9	hSpCas9	negative selection	5349774
87952165	87952187	10	-	27760321	HT29	viability after 10 days	ATCCAGATGATTCTTTAACAGG	PTEN	ENSG00000171862	0.7743785510081986	[44,34]	[74,85,94]	9	hSpCas9	negative selection	5349775
87894065	87894087	10	+	27760321	MOLM13	viability	AAGACTTGAAGGCGTATACAGG	PTEN	ENSG00000171862	0.8210053139495912	[0,0]	[0,0]	6	hSpCas9	negative selection	5433234
87931069	87931091	10	+	27760321	MOLM13	viability	CCGCCAAATTTAATTGCAGAGG	PTEN	ENSG00000171862	1.1435856526670873	[354,289]	[527,290]	7	hSpCas9	negative selection	5433235
87933041	87933063	10	-	27760321	MOLM13	viability	GATAAGTTCTAGCTGTGGTGGG	PTEN	ENSG00000171862	1.2848496136760565	[594,534]	[743,802]	8	hSpCas9	negative selection	5433236
87952114	87952136	10	-	27760321	MOLM13	viability	ACTGGGAATAGTTACTCCCTGG	PTEN	ENSG00000171862	1.7561564118555744	[206,163]	[588,148]	9	hSpCas9	negative selection	5433237
87952165	87952187	10	-	27760321	MOLM13	viability	ATCCAGATGATTCTTTAACAGG	PTEN	ENSG00000171862	-4.837465856507142	[56,44]	[0,0]	-9	hSpCas9	negative selection	5433238
87863580	87863603	10	+	27661255	K562	viability	GCTGCGGCAGGATACGCGCTCGG	PTEN	ENSG00000171862	0.30248113733490267	[388,424]	[456,351]	8	dCas9-KRAB	negative selection	5505063
87863700	87863723	10	+	27661255	K562	viability	GCGAGGGAGATGAGAGACGGCGG	PTEN	ENSG00000171862	0.31033521587990404	[648,642]	[734,558]	8	dCas9-KRAB	negative selection	5505064
87863748	87863771	10	+	27661255	K562	viability	GCGCCTGTGAGCAGCCGCGGGGG	PTEN	ENSG00000171862	0.1743030500076525	[512,584]	[524,466]	6	dCas9-KRAB	negative selection	5505065
87863826	87863849	10	-	27661255	K562	viability	GGTTAGAAAAGACGAAGAGGAGG	PTEN	ENSG00000171862	0.1423218049709758	[1081,945]	[1022,787]	5	dCas9-KRAB	negative selection	5505066
87931068	87931091	10	+	27260156	BXPC3	viability	ACCGCCAAATTTAATTGCAGAGG	PTEN	ENSG00000171862	2.0132036770584625	[338]	[1333,1412,1473,1514]	9	hSpCas9	negative selection	5565387
87931072	87931095	10	-	27260156	BXPC3	viability	CCTACCTCTGCAATTAAATTTGG	PTEN	ENSG00000171862	0.9175742523242391	[166]	[309,245,391,383]	9	hSpCas9	negative selection	5565388
87894029	87894052	10	+	27260156	BXPC3	viability	TTATCCAAACATTATTGCTATGG	PTEN	ENSG00000171862	1.0086867364044165	[307]	[614,580,700,705]	9	hSpCas9	negative selection	5565389
87925537	87925560	10	-	27260156	BXPC3	viability	ACAGATTGTATATCTTGTAATGG	PTEN	ENSG00000171862	0.7668935283436233	[350]	[464,836,572,621]	9	hSpCas9	negative selection	5629646
87931068	87931091	10	+	27260156	A673	viability	ACCGCCAAATTTAATTGCAGAGG	PTEN	ENSG00000171862	1.0685574792778447	[338]	[889,856,766,906]	9	hSpCas9	negative selection	5686638
87931072	87931095	10	-	27260156	A673	viability	CCTACCTCTGCAATTAAATTTGG	PTEN	ENSG00000171862	0.3849746874251698	[166]	[314,299,201,233]	8	hSpCas9	negative selection	5686639
87894029	87894052	10	+	27260156	A673	viability	TTATCCAAACATTATTGCTATGG	PTEN	ENSG00000171862	0.7000176790966764	[307]	[651,599,588,564]	9	hSpCas9	negative selection	5686640
87925537	87925560	10	-	27260156	A673	viability	ACAGATTGTATATCTTGTAATGG	PTEN	ENSG00000171862	0.34679162697206134	[350]	[800,459,391,522]	7	hSpCas9	negative selection	5750897
87931068	87931091	10	+	27260156	A375	viability	ACCGCCAAATTTAATTGCAGAGG	PTEN	ENSG00000171862	1.2646173901469817	[338]	[907,965,1233,722]	9	hSpCas9	negative selection	5807889
87931072	87931095	10	-	27260156	A375	viability	CCTACCTCTGCAATTAAATTTGG	PTEN	ENSG00000171862	0.8851974415111483	[166]	[239,428,341,428]	9	hSpCas9	negative selection	5807890
87894029	87894052	10	+	27260156	A375	viability	TTATCCAAACATTATTGCTATGG	PTEN	ENSG00000171862	0.7164071406135437	[307]	[435,675,579,670]	9	hSpCas9	negative selection	5807891
87925537	87925560	10	-	27260156	A375	viability	ACAGATTGTATATCTTGTAATGG	PTEN	ENSG00000171862	0.43234157567723014	[350]	[357,639,666,555]	6	hSpCas9	negative selection	5872148
87931068	87931091	10	+	27260156	COLO741	viability	ACCGCCAAATTTAATTGCAGAGG	PTEN	ENSG00000171862	0.35636236953091166	[338]	[672,554,451]	7	hSpCas9	negative selection	5929140
87931072	87931095	10	-	27260156	COLO741	viability	CCTACCTCTGCAATTAAATTTGG	PTEN	ENSG00000171862	0.40259166315242356	[166]	[313,360,180]	7	hSpCas9	negative selection	5929141
87894029	87894052	10	+	27260156	COLO741	viability	TTATCCAAACATTATTGCTATGG	PTEN	ENSG00000171862	0.501800807527019	[307]	[807,378,507]	8	hSpCas9	negative selection	5929142
87925537	87925560	10	-	27260156	COLO741	viability	ACAGATTGTATATCTTGTAATGG	PTEN	ENSG00000171862	-0.5470295537238858	[350]	[321,258,337]	-8	hSpCas9	negative selection	5993399
87931068	87931091	10	+	27260156	CAL120	viability	ACCGCCAAATTTAATTGCAGAGG	PTEN	ENSG00000171862	0.6149637629730118	[338]	[1034,401,560]	8	hSpCas9	negative selection	6050391
87931072	87931095	10	-	27260156	CAL120	viability	CCTACCTCTGCAATTAAATTTGG	PTEN	ENSG00000171862	0.32439477211147216	[166]	[381,276,141]	5	hSpCas9	negative selection	6050392
87894029	87894052	10	+	27260156	CAL120	viability	TTATCCAAACATTATTGCTATGG	PTEN	ENSG00000171862	0.37210074515499747	[307]	[533,483,475]	5	hSpCas9	negative selection	6050393
87925537	87925560	10	-	27260156	CAL120	viability	ACAGATTGTATATCTTGTAATGG	PTEN	ENSG00000171862	-0.005906368782934435	[350]	[325,336,621]	0	hSpCas9	negative selection	6114650
87931068	87931091	10	+	27260156	CADOES1	viability	ACCGCCAAATTTAATTGCAGAGG	PTEN	ENSG00000171862	2.0252032955829886	[338]	[1668,1883,603,964]	9	hSpCas9	negative selection	6171642
87931072	87931095	10	-	27260156	CADOES1	viability	CCTACCTCTGCAATTAAATTTGG	PTEN	ENSG00000171862	0.5590817457339213	[166]	[209,316,123,265]	8	hSpCas9	negative selection	6171643
87894029	87894052	10	+	27260156	CADOES1	viability	TTATCCAAACATTATTGCTATGG	PTEN	ENSG00000171862	0.7898357838299104	[307]	[328,691,486,472]	9	hSpCas9	negative selection	6171644
87925537	87925560	10	-	27260156	CADOES1	viability	ACAGATTGTATATCTTGTAATGG	PTEN	ENSG00000171862	1.1553750473831834	[350]	[780,636,488,1011]	9	hSpCas9	negative selection	6235901
87931068	87931091	10	+	27260156	EWS502	viability	ACCGCCAAATTTAATTGCAGAGG	PTEN	ENSG00000171862	0.6004525288272992	[338]	[414,476,502,817]	9	hSpCas9	negative selection	6292893
87931072	87931095	10	-	27260156	EWS502	viability	CCTACCTCTGCAATTAAATTTGG	PTEN	ENSG00000171862	0.5156109897139299	[166]	[341,193,188,277]	8	hSpCas9	negative selection	6292894
87894029	87894052	10	+	27260156	EWS502	viability	TTATCCAAACATTATTGCTATGG	PTEN	ENSG00000171862	0.8491376877243011	[307]	[578,412,638,736]	9	hSpCas9	negative selection	6292895
87925537	87925560	10	-	27260156	EWS502	viability	ACAGATTGTATATCTTGTAATGG	PTEN	ENSG00000171862	-0.7309981596077715	[350]	[137,232,268,268]	-8	hSpCas9	negative selection	6357152
87931068	87931091	10	+	27260156	EW8	viability	ACCGCCAAATTTAATTGCAGAGG	PTEN	ENSG00000171862	0.7247662288955861	[338]	[404,549,471,379]	9	hSpCas9	negative selection	6414144
87931072	87931095	10	-	27260156	EW8	viability	CCTACCTCTGCAATTAAATTTGG	PTEN	ENSG00000171862	0.5454312153248259	[166]	[178,282,125,211]	8	hSpCas9	negative selection	6414145
87894029	87894052	10	+	27260156	EW8	viability	TTATCCAAACATTATTGCTATGG	PTEN	ENSG00000171862	0.6695609171987007	[307]	[407,481,371,330]	9	hSpCas9	negative selection	6414146
87925537	87925560	10	-	27260156	EW8	viability	ACAGATTGTATATCTTGTAATGG	PTEN	ENSG00000171862	-0.10585185650571932	[350]	[306,251,277,221]	-2	hSpCas9	negative selection	6478403
87931068	87931091	10	+	27260156	CORL105	viability	ACCGCCAAATTTAATTGCAGAGG	PTEN	ENSG00000171862	0.043109699633805953	[338]	[303,309,427,593]	0	hSpCas9	negative selection	6535395
87931072	87931095	10	-	27260156	CORL105	viability	CCTACCTCTGCAATTAAATTTGG	PTEN	ENSG00000171862	0.48192636610959405	[166]	[203,195,362,341]	8	hSpCas9	negative selection	6535396
87894029	87894052	10	+	27260156	CORL105	viability	TTATCCAAACATTATTGCTATGG	PTEN	ENSG00000171862	0.4635324562744487	[307]	[520,313,719,472]	8	hSpCas9	negative selection	6535397
87925537	87925560	10	-	27260156	CORL105	viability	ACAGATTGTATATCTTGTAATGG	PTEN	ENSG00000171862	-0.23564919214710384	[350]	[217,409,299,453]	-4	hSpCas9	negative selection	6599654
87931068	87931091	10	+	27260156	HS294T	viability	ACCGCCAAATTTAATTGCAGAGG	PTEN	ENSG00000171862	0.18859037480584012	[338]	[102,138,194,167]	2	hSpCas9	negative selection	6656646
87931072	87931095	10	-	27260156	HS294T	viability	CCTACCTCTGCAATTAAATTTGG	PTEN	ENSG00000171862	0.5368186067597143	[166]	[76,90,99,110]	7	hSpCas9	negative selection	6656647
87894029	87894052	10	+	27260156	HS294T	viability	TTATCCAAACATTATTGCTATGG	PTEN	ENSG00000171862	0.6446002846886278	[307]	[208,165,198,164]	8	hSpCas9	negative selection	6656648
87925537	87925560	10	-	27260156	HS294T	viability	ACAGATTGTATATCTTGTAATGG	PTEN	ENSG00000171862	0.04363025485187921	[350]	[87,109,137,246]	0	hSpCas9	negative selection	6720905
87931068	87931091	10	+	27260156	HCC44	viability	ACCGCCAAATTTAATTGCAGAGG	PTEN	ENSG00000171862	0.0491024530994405	[338]	[388,269,511,447]	0	hSpCas9	negative selection	6777897
87931072	87931095	10	-	27260156	HCC44	viability	CCTACCTCTGCAATTAAATTTGG	PTEN	ENSG00000171862	1.0654909416413645	[166]	[322,342,310,580]	9	hSpCas9	negative selection	6777898
87894029	87894052	10	+	27260156	HCC44	viability	TTATCCAAACATTATTGCTATGG	PTEN	ENSG00000171862	0.39943996087966627	[307]	[537,325,605,416]	6	hSpCas9	negative selection	6777899
87925537	87925560	10	-	27260156	HCC44	viability	ACAGATTGTATATCTTGTAATGG	PTEN	ENSG00000171862	0.294307916270769	[350]	[549,452,488,462]	5	hSpCas9	negative selection	6842156
87931068	87931091	10	+	27260156	G402	viability	ACCGCCAAATTTAATTGCAGAGG	PTEN	ENSG00000171862	2.1924560380802074	[338]	[1412,2012,2099,1963]	9	hSpCas9	negative selection	6899148
87931072	87931095	10	-	27260156	G402	viability	CCTACCTCTGCAATTAAATTTGG	PTEN	ENSG00000171862	0.6617517464730536	[166]	[480,332,222,276]	7	hSpCas9	negative selection	6899149
87894029	87894052	10	+	27260156	G402	viability	TTATCCAAACATTATTGCTATGG	PTEN	ENSG00000171862	1.3870327518380778	[307]	[781,672,1106,1302]	9	hSpCas9	negative selection	6899150
87925537	87925560	10	-	27260156	G402	viability	ACAGATTGTATATCTTGTAATGG	PTEN	ENSG00000171862	1.527776500371824	[350]	[1431,741,1424,1330]	9	hSpCas9	negative selection	6963407
87931068	87931091	10	+	27260156	L33	viability	ACCGCCAAATTTAATTGCAGAGG	PTEN	ENSG00000171862	1.6213692203190895	[338]	[1059,426,637,1053]	9	hSpCas9	negative selection	7020399
87931072	87931095	10	-	27260156	L33	viability	CCTACCTCTGCAATTAAATTTGG	PTEN	ENSG00000171862	0.8530495368849278	[166]	[309,131,214,232]	9	hSpCas9	negative selection	7020400
87894029	87894052	10	+	27260156	L33	viability	TTATCCAAACATTATTGCTATGG	PTEN	ENSG00000171862	0.1177653802263448	[307]	[340,146,209,302]	2	hSpCas9	negative selection	7020401
87925537	87925560	10	-	27260156	L33	viability	ACAGATTGTATATCTTGTAATGG	PTEN	ENSG00000171862	-0.043093322352850016	[350]	[318,224,196,182]	-1	hSpCas9	negative selection	7084658
87931068	87931091	10	+	27260156	K562	viability	ACCGCCAAATTTAATTGCAGAGG	PTEN	ENSG00000171862	-1.662874720768421	[338]	[72,171,61,76]	-9	hSpCas9	negative selection	7141650
87931072	87931095	10	-	27260156	K562	viability	CCTACCTCTGCAATTAAATTTGG	PTEN	ENSG00000171862	0.9284731791873778	[166]	[473,419,237,45]	9	hSpCas9	negative selection	7141651
87894029	87894052	10	+	27260156	K562	viability	TTATCCAAACATTATTGCTATGG	PTEN	ENSG00000171862	0.9897172327190078	[307]	[334,593,668,554]	9	hSpCas9	negative selection	7141652
87925537	87925560	10	-	27260156	K562	viability	ACAGATTGTATATCTTGTAATGG	PTEN	ENSG00000171862	-0.46271761888521984	[350]	[343,260,124,188]	-5	hSpCas9	negative selection	7205909
87931068	87931091	10	+	27260156	HT29	viability	ACCGCCAAATTTAATTGCAGAGG	PTEN	ENSG00000171862	1.0976304448898508	[338]	[991,1012,825,728]	9	hSpCas9	negative selection	7262901
87931072	87931095	10	-	27260156	HT29	viability	CCTACCTCTGCAATTAAATTTGG	PTEN	ENSG00000171862	0.7925503106826881	[166]	[430,346,282,348]	9	hSpCas9	negative selection	7262902
87894029	87894052	10	+	27260156	HT29	viability	TTATCCAAACATTATTGCTATGG	PTEN	ENSG00000171862	0.5499626464447371	[307]	[597,447,626,514]	9	hSpCas9	negative selection	7262903
87925537	87925560	10	-	27260156	HT29	viability	ACAGATTGTATATCTTGTAATGG	PTEN	ENSG00000171862	-0.044205342820200444	[350]	[640,310,466,260]	-1	hSpCas9	negative selection	7327160
87931068	87931091	10	+	27260156	MHHES1	viability	ACCGCCAAATTTAATTGCAGAGG	PTEN	ENSG00000171862	2.115051217348176	[338]	[1116,1958,2287,1273]	9	hSpCas9	negative selection	7384152
87931072	87931095	10	-	27260156	MHHES1	viability	CCTACCTCTGCAATTAAATTTGG	PTEN	ENSG00000171862	0.9594806494010876	[166]	[443,539,291,235]	9	hSpCas9	negative selection	7384153
87894029	87894052	10	+	27260156	MHHES1	viability	TTATCCAAACATTATTGCTATGG	PTEN	ENSG00000171862	1.464234231172394	[307]	[719,1021,1227,842]	9	hSpCas9	negative selection	7384154
87925537	87925560	10	-	27260156	MHHES1	viability	ACAGATTGTATATCTTGTAATGG	PTEN	ENSG00000171862	1.095543987319905	[350]	[1004,799,908,695]	9	hSpCas9	negative selection	7448411
87931068	87931091	10	+	27260156	MEWO	viability	ACCGCCAAATTTAATTGCAGAGG	PTEN	ENSG00000171862	1.0905466666595967	[338]	[548,788,662]	9	hSpCas9	negative selection	7505403
87931072	87931095	10	-	27260156	MEWO	viability	CCTACCTCTGCAATTAAATTTGG	PTEN	ENSG00000171862	-0.04758386396207781	[166]	[199,137,124]	-1	hSpCas9	negative selection	7505404
87894029	87894052	10	+	27260156	MEWO	viability	TTATCCAAACATTATTGCTATGG	PTEN	ENSG00000171862	0.3575783784557461	[307]	[421,318,376]	7	hSpCas9	negative selection	7505405
87925537	87925560	10	-	27260156	MEWO	viability	ACAGATTGTATATCTTGTAATGG	PTEN	ENSG00000171862	-0.33302298027087524	[350]	[254,243,281]	-6	hSpCas9	negative selection	7569662
87931068	87931091	10	+	27260156	LNCAPCLONEFGC	viability	ACCGCCAAATTTAATTGCAGAGG	PTEN	ENSG00000171862	0.30575509158000214	[338]	[266,381,405,468]	5	hSpCas9	negative selection	7626654
87931072	87931095	10	-	27260156	LNCAPCLONEFGC	viability	CCTACCTCTGCAATTAAATTTGG	PTEN	ENSG00000171862	1.1143951441841127	[166]	[342,445,234,263]	9	hSpCas9	negative selection	7626655
87894029	87894052	10	+	27260156	LNCAPCLONEFGC	viability	TTATCCAAACATTATTGCTATGG	PTEN	ENSG00000171862	0.5671598179748925	[307]	[335,441,636,270]	8	hSpCas9	negative selection	7626656
87925537	87925560	10	-	27260156	LNCAPCLONEFGC	viability	ACAGATTGTATATCTTGTAATGG	PTEN	ENSG00000171862	-0.47672683009829536	[350]	[193,133,216,373]	-6	hSpCas9	negative selection	7690913
87931068	87931091	10	+	27260156	PANC0327	viability	ACCGCCAAATTTAATTGCAGAGG	PTEN	ENSG00000171862	1.0983001323748236	[338]	[591,266,691,1071]	9	hSpCas9	negative selection	7747905
87931072	87931095	10	-	27260156	PANC0327	viability	CCTACCTCTGCAATTAAATTTGG	PTEN	ENSG00000171862	0.49409478313836985	[166]	[263,115,138,332]	7	hSpCas9	negative selection	7747906
87894029	87894052	10	+	27260156	PANC0327	viability	TTATCCAAACATTATTGCTATGG	PTEN	ENSG00000171862	0.7461829099847714	[307]	[457,219,825,362]	9	hSpCas9	negative selection	7747907
87925537	87925560	10	-	27260156	PANC0327	viability	ACAGATTGTATATCTTGTAATGG	PTEN	ENSG00000171862	1.1324992182178262	[350]	[1472,303,671,398]	9	hSpCas9	negative selection	7812164
87931068	87931091	10	+	27260156	NCIH2009	viability	ACCGCCAAATTTAATTGCAGAGG	PTEN	ENSG00000171862	1.716154053734901	[338]	[2074,1469,1224]	9	hSpCas9	negative selection	7869156
87931072	87931095	10	-	27260156	NCIH2009	viability	CCTACCTCTGCAATTAAATTTGG	PTEN	ENSG00000171862	0.6076478802095711	[166]	[445,348,288]	8	hSpCas9	negative selection	7869157
87894029	87894052	10	+	27260156	NCIH2009	viability	TTATCCAAACATTATTGCTATGG	PTEN	ENSG00000171862	0.8127195091805337	[307]	[705,671,879]	9	hSpCas9	negative selection	7869158
87925537	87925560	10	-	27260156	NCIH2009	viability	ACAGATTGTATATCTTGTAATGG	PTEN	ENSG00000171862	1.0793232300722995	[350]	[844,879,1346]	9	hSpCas9	negative selection	7933415
87931068	87931091	10	+	27260156	NCIH1373	viability	ACCGCCAAATTTAATTGCAGAGG	PTEN	ENSG00000171862	1.6214233724625535	[338]	[1472,1181,1251,205]	9	hSpCas9	negative selection	7990407
87931072	87931095	10	-	27260156	NCIH1373	viability	CCTACCTCTGCAATTAAATTTGG	PTEN	ENSG00000171862	0.655152549356263	[166]	[201,198,457,81]	6	hSpCas9	negative selection	7990408
87894029	87894052	10	+	27260156	NCIH1373	viability	TTATCCAAACATTATTGCTATGG	PTEN	ENSG00000171862	1.0390699907698213	[307]	[695,425,402,363]	9	hSpCas9	negative selection	7990409
87925537	87925560	10	-	27260156	NCIH1373	viability	ACAGATTGTATATCTTGTAATGG	PTEN	ENSG00000171862	-0.22489335173957165	[350]	[196,312,550,66]	-2	hSpCas9	negative selection	8054666
87931068	87931091	10	+	27260156	PATU8902	viability	ACCGCCAAATTTAATTGCAGAGG	PTEN	ENSG00000171862	1.4405753907928043	[338]	[1487,1054,819,1948]	9	hSpCas9	negative selection	8111658
87931072	87931095	10	-	27260156	PATU8902	viability	CCTACCTCTGCAATTAAATTTGG	PTEN	ENSG00000171862	0.8552440365453795	[166]	[499,243,333,649]	8	hSpCas9	negative selection	8111659
87894029	87894052	10	+	27260156	PATU8902	viability	TTATCCAAACATTATTGCTATGG	PTEN	ENSG00000171862	1.6150128912657133	[307]	[2163,970,895,1309]	9	hSpCas9	negative selection	8111660
87925537	87925560	10	-	27260156	PATU8902	viability	ACAGATTGTATATCTTGTAATGG	PTEN	ENSG00000171862	1.0147961177260107	[350]	[638,1629,747,995]	9	hSpCas9	negative selection	8175917
87931068	87931091	10	+	27260156	PANC1	viability	ACCGCCAAATTTAATTGCAGAGG	PTEN	ENSG00000171862	1.7480877292913308	[338]	[1096,1034,1147,676]	9	hSpCas9	negative selection	8232909
87931072	87931095	10	-	27260156	PANC1	viability	CCTACCTCTGCAATTAAATTTGG	PTEN	ENSG00000171862	0.5471236183795066	[166]	[249,227,220,148]	8	hSpCas9	negative selection	8232910
87894029	87894052	10	+	27260156	PANC1	viability	TTATCCAAACATTATTGCTATGG	PTEN	ENSG00000171862	1.111309099938318	[307]	[520,718,665,426]	9	hSpCas9	negative selection	8232911
87925537	87925560	10	-	27260156	PANC1	viability	ACAGATTGTATATCTTGTAATGG	PTEN	ENSG00000171862	0.7106738002667531	[350]	[376,303,458,745]	9	hSpCas9	negative selection	8297168
87931068	87931091	10	+	27260156	PANC0813	viability	ACCGCCAAATTTAATTGCAGAGG	PTEN	ENSG00000171862	1.5285596461626656	[338]	[1490,889,925,1307]	9	hSpCas9	negative selection	8354160
87931072	87931095	10	-	27260156	PANC0813	viability	CCTACCTCTGCAATTAAATTTGG	PTEN	ENSG00000171862	1.0002446901556556	[166]	[394,292,562,322]	9	hSpCas9	negative selection	8354161
87894029	87894052	10	+	27260156	PANC0813	viability	TTATCCAAACATTATTGCTATGG	PTEN	ENSG00000171862	0.6341733332820614	[307]	[587,507,525,621]	8	hSpCas9	negative selection	8354162
87925537	87925560	10	-	27260156	PANC0813	viability	ACAGATTGTATATCTTGTAATGG	PTEN	ENSG00000171862	0.6277690144390687	[350]	[1070,662,397,463]	8	hSpCas9	negative selection	8418419
87931068	87931091	10	+	27260156	RDES	viability	ACCGCCAAATTTAATTGCAGAGG	PTEN	ENSG00000171862	1.6430434354175079	[338]	[962,1171,1230,1583]	9	hSpCas9	negative selection	8475411
87931072	87931095	10	-	27260156	RDES	viability	CCTACCTCTGCAATTAAATTTGG	PTEN	ENSG00000171862	0.7187335944619021	[166]	[253,380,346,273]	9	hSpCas9	negative selection	8475412
87894029	87894052	10	+	27260156	RDES	viability	TTATCCAAACATTATTGCTATGG	PTEN	ENSG00000171862	1.021812510516185	[307]	[613,656,840,785]	9	hSpCas9	negative selection	8475413
87925537	87925560	10	-	27260156	RDES	viability	ACAGATTGTATATCTTGTAATGG	PTEN	ENSG00000171862	0.5303780327857311	[350]	[516,427,593,844]	8	hSpCas9	negative selection	8539670
87931068	87931091	10	+	27260156	PC3	viability	ACCGCCAAATTTAATTGCAGAGG	PTEN	ENSG00000171862	0.47607974786256035	[338]	[170,424,1026,584]	8	hSpCas9	negative selection	8596662
87931072	87931095	10	-	27260156	PC3	viability	CCTACCTCTGCAATTAAATTTGG	PTEN	ENSG00000171862	0.3567924801420861	[166]	[152,167,360,234]	7	hSpCas9	negative selection	8596663
87894029	87894052	10	+	27260156	PC3	viability	TTATCCAAACATTATTGCTATGG	PTEN	ENSG00000171862	0.7481233739672348	[307]	[320,334,1281,468]	9	hSpCas9	negative selection	8596664
87925537	87925560	10	-	27260156	PC3	viability	ACAGATTGTATATCTTGTAATGG	PTEN	ENSG00000171862	-0.43495815564474544	[350]	[111,217,735,201]	-7	hSpCas9	negative selection	8660921
87931068	87931091	10	+	27260156	PATU8988T	viability	ACCGCCAAATTTAATTGCAGAGG	PTEN	ENSG00000171862	0.9472030911651093	[338]	[299,590,881,755]	9	hSpCas9	negative selection	8717913
87931072	87931095	10	-	27260156	PATU8988T	viability	CCTACCTCTGCAATTAAATTTGG	PTEN	ENSG00000171862	0.28667231750029876	[166]	[208,211,191,173]	5	hSpCas9	negative selection	8717914
87894029	87894052	10	+	27260156	PATU8988T	viability	TTATCCAAACATTATTGCTATGG	PTEN	ENSG00000171862	0.9614329185685081	[307]	[743,597,549,414]	9	hSpCas9	negative selection	8717915
87925537	87925560	10	-	27260156	PATU8988T	viability	ACAGATTGTATATCTTGTAATGG	PTEN	ENSG00000171862	0.3269602030847273	[350]	[211,555,573,364]	5	hSpCas9	negative selection	8782172
87931068	87931091	10	+	27260156	T47D	viability	ACCGCCAAATTTAATTGCAGAGG	PTEN	ENSG00000171862	0.1872138094574634	[338]	[455,389,461,496]	4	hSpCas9	negative selection	8839164
87931072	87931095	10	-	27260156	T47D	viability	CCTACCTCTGCAATTAAATTTGG	PTEN	ENSG00000171862	0.5997088407226597	[166]	[275,271,305,327]	9	hSpCas9	negative selection	8839165
87894029	87894052	10	+	27260156	T47D	viability	TTATCCAAACATTATTGCTATGG	PTEN	ENSG00000171862	0.6137527123461006	[307]	[501,525,574,595]	9	hSpCas9	negative selection	8839166
87925537	87925560	10	-	27260156	T47D	viability	ACAGATTGTATATCTTGTAATGG	PTEN	ENSG00000171862	-0.22377102928796583	[350]	[379,379,288,349]	-5	hSpCas9	negative selection	8903423
87931068	87931091	10	+	27260156	SU8686	viability	ACCGCCAAATTTAATTGCAGAGG	PTEN	ENSG00000171862	-0.09712634315865343	[338]	[273,324,298,367]	-2	hSpCas9	negative selection	8960415
87931072	87931095	10	-	27260156	SU8686	viability	CCTACCTCTGCAATTAAATTTGG	PTEN	ENSG00000171862	0.6397798390896009	[166]	[223,98,378,374]	9	hSpCas9	negative selection	8960416
87894029	87894052	10	+	27260156	SU8686	viability	TTATCCAAACATTATTGCTATGG	PTEN	ENSG00000171862	0.5402610969856462	[307]	[382,427,481,498]	8	hSpCas9	negative selection	8960417
87925537	87925560	10	-	27260156	SU8686	viability	ACAGATTGTATATCTTGTAATGG	PTEN	ENSG00000171862	-0.4029375523831911	[350]	[262,249,300,234]	-6	hSpCas9	negative selection	9024674
87931068	87931091	10	+	27260156	SKES1	viability	ACCGCCAAATTTAATTGCAGAGG	PTEN	ENSG00000171862	0.9586558290765836	[338]	[790,650,705,508]	9	hSpCas9	negative selection	9081666
87931072	87931095	10	-	27260156	SKES1	viability	CCTACCTCTGCAATTAAATTTGG	PTEN	ENSG00000171862	0.6133717198684132	[166]	[342,209,246,226]	9	hSpCas9	negative selection	9081667
87894029	87894052	10	+	27260156	SKES1	viability	TTATCCAAACATTATTGCTATGG	PTEN	ENSG00000171862	0.6309950193044745	[307]	[636,473,447,373]	9	hSpCas9	negative selection	9081668
87925537	87925560	10	-	27260156	SKES1	viability	ACAGATTGTATATCTTGTAATGG	PTEN	ENSG00000171862	-0.5814740703149537	[350]	[353,257,163,183]	-8	hSpCas9	negative selection	9145925
87931068	87931091	10	+	27260156	TOV112D	viability	ACCGCCAAATTTAATTGCAGAGG	PTEN	ENSG00000171862	0.6659117644729741	[338]	[493,756,348,601]	9	hSpCas9	negative selection	9202917
87931072	87931095	10	-	27260156	TOV112D	viability	CCTACCTCTGCAATTAAATTTGG	PTEN	ENSG00000171862	-0.1631696348550009	[166]	[72,204,158,166]	-3	hSpCas9	negative selection	9202918
87894029	87894052	10	+	27260156	TOV112D	viability	TTATCCAAACATTATTGCTATGG	PTEN	ENSG00000171862	0.34450553953950386	[307]	[394,449,354,380]	6	hSpCas9	negative selection	9202919
87925537	87925560	10	-	27260156	TOV112D	viability	ACAGATTGTATATCTTGTAATGG	PTEN	ENSG00000171862	-0.6675747696759546	[350]	[236,226,251,172]	-8	hSpCas9	negative selection	9267176
87931068	87931091	10	+	27260156	TC71	viability	ACCGCCAAATTTAATTGCAGAGG	PTEN	ENSG00000171862	1.2547257365332716	[338]	[642,999,774,1070]	9	hSpCas9	negative selection	9324168
87931072	87931095	10	-	27260156	TC71	viability	CCTACCTCTGCAATTAAATTTGG	PTEN	ENSG00000171862	0.5293948965518803	[166]	[233,204,249,350]	9	hSpCas9	negative selection	9324169
87894029	87894052	10	+	27260156	TC71	viability	TTATCCAAACATTATTGCTATGG	PTEN	ENSG00000171862	0.5384430948285581	[307]	[486,409,458,567]	9	hSpCas9	negative selection	9324170
87925537	87925560	10	-	27260156	TC71	viability	ACAGATTGTATATCTTGTAATGG	PTEN	ENSG00000171862	0.07726316896295982	[350]	[339,377,387,488]	2	hSpCas9	negative selection	9388427
87931068	87931091	10	+	27260156	TC32	viability	ACCGCCAAATTTAATTGCAGAGG	PTEN	ENSG00000171862	5.480743524989114	[338]	[13424,9983,13808,20856]	10	hSpCas9	negative selection	9445419
87931072	87931095	10	-	27260156	TC32	viability	CCTACCTCTGCAATTAAATTTGG	PTEN	ENSG00000171862	1.959904638893988	[166]	[469,681,712,540]	9	hSpCas9	negative selection	9445420
87894029	87894052	10	+	27260156	TC32	viability	TTATCCAAACATTATTGCTATGG	PTEN	ENSG00000171862	2.7871897099929894	[307]	[1928,775,3579,2372]	9	hSpCas9	negative selection	9445421
87925537	87925560	10	-	27260156	TC32	viability	ACAGATTGTATATCTTGTAATGG	PTEN	ENSG00000171862	3.856897578024152	[350]	[4311,3385,7762,4465]	9	hSpCas9	negative selection	9509678
87931068	87931091	10	+	28162770	P31FUJ	viability	ACCGCCAAATTTAATTGCAGAGG	PTEN	ENSG00000171862	0.38017467247637415	[203]	[311]	4	hSpCas9	negative selection	10219381
87933132	87933155	10	+	28162770	P31FUJ	viability	AAAGCTGGAAAGGGACGAACTGG	PTEN	ENSG00000171862	0.14215785548913012	[218]	[283]	1	hSpCas9	negative selection	10219382
87957910	87957933	10	-	28162770	P31FUJ	viability	GAACTTGTCTTCCCGTCGTGTGG	PTEN	ENSG00000171862	0.6433915939712236	[151]	[278]	7	hSpCas9	negative selection	10219383
87957899	87957922	10	+	28162770	P31FUJ	viability	CAATTCAGGACCCACACGACGGG	PTEN	ENSG00000171862	0.9780945780842398	[377]	[874]	9	hSpCas9	negative selection	10219384
87952177	87952200	10	+	28162770	P31FUJ	viability	TCATCTGGATTATAGACCAGTGG	PTEN	ENSG00000171862	-0.17514741199416872	[465]	[484]	-2	hSpCas9	negative selection	10219385
87933045	87933068	10	-	28162770	P31FUJ	viability	GGTTTGATAAGTTCTAGCTGTGG	PTEN	ENSG00000171862	1.1721816302005423	[53]	[142]	9	hSpCas9	negative selection	10219386
87961010	87961033	10	+	28162770	P31FUJ	viability	AGAGCGTGCAGATAATGACAAGG	PTEN	ENSG00000171862	0.13803549095393008	[115]	[149]	1	hSpCas9	negative selection	10219387
87952235	87952258	10	-	28162770	P31FUJ	viability	CAAGTTCCGCCACTGAACATTGG	PTEN	ENSG00000171862	-0.1169877117057323	[657]	[712]	-1	hSpCas9	negative selection	10219388
87864477	87864500	10	-	28162770	P31FUJ	viability	GCTAACGATCTCTTTGATGATGG	PTEN	ENSG00000171862	0.8006479893093846	[404]	[828]	8	hSpCas9	negative selection	10219389
87933117	87933140	10	+	28162770	P31FUJ	viability	GCAGCAATTCACTGTAAAGCTGG	PTEN	ENSG00000171862	0.32070286478518006	[339]	[498]	3	hSpCas9	negative selection	10219390
87931068	87931091	10	+	28162770	TF1	viability	ACCGCCAAATTTAATTGCAGAGG	PTEN	ENSG00000171862	NaN	[NaN]	[197]	1	hSpCas9	negative selection	10388747
87933132	87933155	10	+	28162770	TF1	viability	AAAGCTGGAAAGGGACGAACTGG	PTEN	ENSG00000171862	NaN	[NaN]	[82]	1	hSpCas9	negative selection	10388748
87957910	87957933	10	-	28162770	TF1	viability	GAACTTGTCTTCCCGTCGTGTGG	PTEN	ENSG00000171862	NaN	[NaN]	[103]	1	hSpCas9	negative selection	10388749
87957899	87957922	10	+	28162770	TF1	viability	CAATTCAGGACCCACACGACGGG	PTEN	ENSG00000171862	NaN	[NaN]	[301]	1	hSpCas9	negative selection	10388750
87952177	87952200	10	+	28162770	TF1	viability	TCATCTGGATTATAGACCAGTGG	PTEN	ENSG00000171862	NaN	[NaN]	[111]	1	hSpCas9	negative selection	10388751
87933045	87933068	10	-	28162770	TF1	viability	GGTTTGATAAGTTCTAGCTGTGG	PTEN	ENSG00000171862	NaN	[NaN]	[12]	1	hSpCas9	negative selection	10388752
87961010	87961033	10	+	28162770	TF1	viability	AGAGCGTGCAGATAATGACAAGG	PTEN	ENSG00000171862	NaN	[NaN]	[81]	1	hSpCas9	negative selection	10388753
87952235	87952258	10	-	28162770	TF1	viability	CAAGTTCCGCCACTGAACATTGG	PTEN	ENSG00000171862	NaN	[NaN]	[581]	1	hSpCas9	negative selection	10388754
87864477	87864500	10	-	28162770	TF1	viability	GCTAACGATCTCTTTGATGATGG	PTEN	ENSG00000171862	NaN	[NaN]	[488]	1	hSpCas9	negative selection	10388755
87933117	87933140	10	+	28162770	TF1	viability	GCAGCAATTCACTGTAAAGCTGG	PTEN	ENSG00000171862	NaN	[NaN]	[200]	1	hSpCas9	negative selection	10388756
87931068	87931091	10	+	28162770	SKM1	viability	ACCGCCAAATTTAATTGCAGAGG	PTEN	ENSG00000171862	3.4835008489522457	[52]	[1047]	9	hSpCas9	negative selection	10558113
87933132	87933155	10	+	28162770	SKM1	viability	AAAGCTGGAAAGGGACGAACTGG	PTEN	ENSG00000171862	1.9487346327994448	[56]	[388]	9	hSpCas9	negative selection	10558114
87957910	87957933	10	-	28162770	SKM1	viability	GAACTTGTCTTCCCGTCGTGTGG	PTEN	ENSG00000171862	3.2249617809485813	[50]	[842]	9	hSpCas9	negative selection	10558115
87957899	87957922	10	+	28162770	SKM1	viability	CAATTCAGGACCCACACGACGGG	PTEN	ENSG00000171862	4.099889655611379	[117]	[3576]	9	hSpCas9	negative selection	10558116
87952177	87952200	10	+	28162770	SKM1	viability	TCATCTGGATTATAGACCAGTGG	PTEN	ENSG00000171862	3.2437344531483356	[121]	[2042]	9	hSpCas9	negative selection	10558117
87933045	87933068	10	-	28162770	SKM1	viability	GGTTTGATAAGTTCTAGCTGTGG	PTEN	ENSG00000171862	4.046306435267462	[23]	[700]	9	hSpCas9	negative selection	10558118
87961010	87961033	10	+	28162770	SKM1	viability	AGAGCGTGCAGATAATGACAAGG	PTEN	ENSG00000171862	2.4089527368178665	[35]	[337]	9	hSpCas9	negative selection	10558119
87952235	87952258	10	-	28162770	SKM1	viability	CAAGTTCCGCCACTGAACATTGG	PTEN	ENSG00000171862	3.1965851996348245	[240]	[3905]	9	hSpCas9	negative selection	10558120
87864477	87864500	10	-	28162770	SKM1	viability	GCTAACGATCTCTTTGATGATGG	PTEN	ENSG00000171862	2.9963824077311383	[120]	[1706]	9	hSpCas9	negative selection	10558121
87933117	87933140	10	+	28162770	SKM1	viability	GCAGCAATTCACTGTAAAGCTGG	PTEN	ENSG00000171862	3.374020740122711	[69]	[1282]	9	hSpCas9	negative selection	10558122
87931068	87931091	10	+	28162770	SKM1	viability	ACCGCCAAATTTAATTGCAGAGG	PTEN	ENSG00000171862	3.4835008489522457	[52]	[1047]	9	hSpCas9	negative selection	10727479
87933132	87933155	10	+	28162770	SKM1	viability	AAAGCTGGAAAGGGACGAACTGG	PTEN	ENSG00000171862	1.9487346327994448	[56]	[388]	9	hSpCas9	negative selection	10727480
87957910	87957933	10	-	28162770	SKM1	viability	GAACTTGTCTTCCCGTCGTGTGG	PTEN	ENSG00000171862	3.2249617809485813	[50]	[842]	9	hSpCas9	negative selection	10727481
87957899	87957922	10	+	28162770	SKM1	viability	CAATTCAGGACCCACACGACGGG	PTEN	ENSG00000171862	4.099889655611379	[117]	[3576]	9	hSpCas9	negative selection	10727482
87952177	87952200	10	+	28162770	SKM1	viability	TCATCTGGATTATAGACCAGTGG	PTEN	ENSG00000171862	3.2437344531483356	[121]	[2042]	9	hSpCas9	negative selection	10727483
87933045	87933068	10	-	28162770	SKM1	viability	GGTTTGATAAGTTCTAGCTGTGG	PTEN	ENSG00000171862	4.046306435267462	[23]	[700]	9	hSpCas9	negative selection	10727484
87961010	87961033	10	+	28162770	SKM1	viability	AGAGCGTGCAGATAATGACAAGG	PTEN	ENSG00000171862	2.4089527368178665	[35]	[337]	9	hSpCas9	negative selection	10727485
87952235	87952258	10	-	28162770	SKM1	viability	CAAGTTCCGCCACTGAACATTGG	PTEN	ENSG00000171862	3.1965851996348245	[240]	[3905]	9	hSpCas9	negative selection	10727486
87864477	87864500	10	-	28162770	SKM1	viability	GCTAACGATCTCTTTGATGATGG	PTEN	ENSG00000171862	2.9963824077311383	[120]	[1706]	9	hSpCas9	negative selection	10727487
87933117	87933140	10	+	28162770	SKM1	viability	GCAGCAATTCACTGTAAAGCTGG	PTEN	ENSG00000171862	3.374020740122711	[69]	[1282]	9	hSpCas9	negative selection	10727488
87931068	87931091	10	+	28162770	PL21	viability	ACCGCCAAATTTAATTGCAGAGG	PTEN	ENSG00000171862	0.40900504489004635	[198]	[114]	3	hSpCas9	negative selection	10896845
87933132	87933155	10	+	28162770	PL21	viability	AAAGCTGGAAAGGGACGAACTGG	PTEN	ENSG00000171862	-0.14678285986491157	[261]	[102]	-1	hSpCas9	negative selection	10896846
87957910	87957933	10	-	28162770	PL21	viability	GAACTTGTCTTCCCGTCGTGTGG	PTEN	ENSG00000171862	-0.6463151272572243	[186]	[51]	-4	hSpCas9	negative selection	10896847
87957899	87957922	10	+	28162770	PL21	viability	CAATTCAGGACCCACACGACGGG	PTEN	ENSG00000171862	1.9726507472511066	[448]	[766]	9	hSpCas9	negative selection	10896848
87952177	87952200	10	+	28162770	PL21	viability	TCATCTGGATTATAGACCAGTGG	PTEN	ENSG00000171862	0.47160264239369454	[511]	[308]	4	hSpCas9	negative selection	10896849
87933045	87933068	10	-	28162770	PL21	viability	GGTTTGATAAGTTCTAGCTGTGG	PTEN	ENSG00000171862	0.5627096938740285	[83]	[53]	5	hSpCas9	negative selection	10896850
87961010	87961033	10	+	28162770	PL21	viability	AGAGCGTGCAGATAATGACAAGG	PTEN	ENSG00000171862	2.3457449367362195	[112]	[249]	9	hSpCas9	negative selection	10896851
87952235	87952258	10	-	28162770	PL21	viability	CAAGTTCCGCCACTGAACATTGG	PTEN	ENSG00000171862	0.25231507950218224	[705]	[365]	2	hSpCas9	negative selection	10896852
87864477	87864500	10	-	28162770	PL21	viability	GCTAACGATCTCTTTGATGATGG	PTEN	ENSG00000171862	0.3995579210271425	[424]	[243]	3	hSpCas9	negative selection	10896853
87933117	87933140	10	+	28162770	PL21	viability	GCAGCAATTCACTGTAAAGCTGG	PTEN	ENSG00000171862	0.9550271166527888	[223]	[188]	7	hSpCas9	negative selection	10896854
87931068	87931091	10	+	28162770	P31FUJ	viability	ACCGCCAAATTTAATTGCAGAGG	PTEN	ENSG00000171862	0.38017467247637415	[203]	[311]	4	hSpCas9	negative selection	11066211
87933132	87933155	10	+	28162770	P31FUJ	viability	AAAGCTGGAAAGGGACGAACTGG	PTEN	ENSG00000171862	0.14215785548913012	[218]	[283]	1	hSpCas9	negative selection	11066212
87957910	87957933	10	-	28162770	P31FUJ	viability	GAACTTGTCTTCCCGTCGTGTGG	PTEN	ENSG00000171862	0.6433915939712236	[151]	[278]	7	hSpCas9	negative selection	11066213
87957899	87957922	10	+	28162770	P31FUJ	viability	CAATTCAGGACCCACACGACGGG	PTEN	ENSG00000171862	0.9780945780842398	[377]	[874]	9	hSpCas9	negative selection	11066214
87952177	87952200	10	+	28162770	P31FUJ	viability	TCATCTGGATTATAGACCAGTGG	PTEN	ENSG00000171862	-0.17514741199416872	[465]	[484]	-2	hSpCas9	negative selection	11066215
87933045	87933068	10	-	28162770	P31FUJ	viability	GGTTTGATAAGTTCTAGCTGTGG	PTEN	ENSG00000171862	1.1721816302005423	[53]	[142]	9	hSpCas9	negative selection	11066216
87961010	87961033	10	+	28162770	P31FUJ	viability	AGAGCGTGCAGATAATGACAAGG	PTEN	ENSG00000171862	0.13803549095393008	[115]	[149]	1	hSpCas9	negative selection	11066217
87952235	87952258	10	-	28162770	P31FUJ	viability	CAAGTTCCGCCACTGAACATTGG	PTEN	ENSG00000171862	-0.1169877117057323	[657]	[712]	-1	hSpCas9	negative selection	11066218
87864477	87864500	10	-	28162770	P31FUJ	viability	GCTAACGATCTCTTTGATGATGG	PTEN	ENSG00000171862	0.8006479893093846	[404]	[828]	8	hSpCas9	negative selection	11066219
87933117	87933140	10	+	28162770	P31FUJ	viability	GCAGCAATTCACTGTAAAGCTGG	PTEN	ENSG00000171862	0.32070286478518006	[339]	[498]	3	hSpCas9	negative selection	11066220
87931068	87931091	10	+	28162770	OCIAML5	viability	ACCGCCAAATTTAATTGCAGAGG	PTEN	ENSG00000171862	0.5506225359872019	[131]	[348]	5	hSpCas9	negative selection	11235577
87933132	87933155	10	+	28162770	OCIAML5	viability	AAAGCTGGAAAGGGACGAACTGG	PTEN	ENSG00000171862	1.0059144242635751	[127]	[463]	8	hSpCas9	negative selection	11235578
87957910	87957933	10	-	28162770	OCIAML5	viability	GAACTTGTCTTCCCGTCGTGTGG	PTEN	ENSG00000171862	1.1511501418195458	[111]	[448]	8	hSpCas9	negative selection	11235579
87957899	87957922	10	+	28162770	OCIAML5	viability	CAATTCAGGACCCACACGACGGG	PTEN	ENSG00000171862	1.3548958099028452	[187]	[867]	9	hSpCas9	negative selection	11235580
87952177	87952200	10	+	28162770	OCIAML5	viability	TCATCTGGATTATAGACCAGTGG	PTEN	ENSG00000171862	1.7742798506222788	[188]	[1166]	9	hSpCas9	negative selection	11235581
87933045	87933068	10	-	28162770	OCIAML5	viability	GGTTTGATAAGTTCTAGCTGTGG	PTEN	ENSG00000171862	1.9076703309608671	[21]	[148]	9	hSpCas9	negative selection	11235582
87961010	87961033	10	+	28162770	OCIAML5	viability	AGAGCGTGCAGATAATGACAAGG	PTEN	ENSG00000171862	0.7269466635259728	[80]	[241]	6	hSpCas9	negative selection	11235583
87952235	87952258	10	-	28162770	OCIAML5	viability	CAAGTTCCGCCACTGAACATTGG	PTEN	ENSG00000171862	0.30993791473855214	[689]	[1543]	2	hSpCas9	negative selection	11235584
87864477	87864500	10	-	28162770	OCIAML5	viability	GCTAACGATCTCTTTGATGATGG	PTEN	ENSG00000171862	0.7298682371595908	[317]	[951]	6	hSpCas9	negative selection	11235585
87933117	87933140	10	+	28162770	OCIAML5	viability	GCAGCAATTCACTGTAAAGCTGG	PTEN	ENSG00000171862	0.944270685963871	[168]	[586]	7	hSpCas9	negative selection	11235586
87931068	87931091	10	+	28162770	EOL1	viability	ACCGCCAAATTTAATTGCAGAGG	PTEN	ENSG00000171862	0.5619776921858264	[314]	[244]	5	hSpCas9	negative selection	11404943
87933132	87933155	10	+	28162770	EOL1	viability	AAAGCTGGAAAGGGACGAACTGG	PTEN	ENSG00000171862	-0.931716750968016	[209]	[57]	-6	hSpCas9	negative selection	11404944
87957910	87957933	10	-	28162770	EOL1	viability	GAACTTGTCTTCCCGTCGTGTGG	PTEN	ENSG00000171862	-1.596989349008988	[355]	[61]	-7	hSpCas9	negative selection	11404945
87957899	87957922	10	+	28162770	EOL1	viability	CAATTCAGGACCCACACGACGGG	PTEN	ENSG00000171862	-0.8621391010038798	[796]	[230]	-6	hSpCas9	negative selection	11404946
87952177	87952200	10	+	28162770	EOL1	viability	TCATCTGGATTATAGACCAGTGG	PTEN	ENSG00000171862	-1.6409782496862115	[810]	[136]	-7	hSpCas9	negative selection	11404947
87933045	87933068	10	-	28162770	EOL1	viability	GGTTTGATAAGTTCTAGCTGTGG	PTEN	ENSG00000171862	-3.640236847212991	[141]	[5]	-9	hSpCas9	negative selection	11404948
87961010	87961033	10	+	28162770	EOL1	viability	AGAGCGTGCAGATAATGACAAGG	PTEN	ENSG00000171862	-0.6723873708166976	[120]	[39]	-5	hSpCas9	negative selection	11404949
87952235	87952258	10	-	28162770	EOL1	viability	CAAGTTCCGCCACTGAACATTGG	PTEN	ENSG00000171862	-2.563738709738948	[807]	[71]	-8	hSpCas9	negative selection	11404950
87864477	87864500	10	-	28162770	EOL1	viability	GCTAACGATCTCTTTGATGATGG	PTEN	ENSG00000171862	-0.6030124181056997	[541]	[187]	-4	hSpCas9	negative selection	11404951
87933117	87933140	10	+	28162770	EOL1	viability	GCAGCAATTCACTGTAAAGCTGG	PTEN	ENSG00000171862	0.031462975487046435	[324]	[174]	0	hSpCas9	negative selection	11404952
87931068	87931091	10	+	28162770	MOLM13	viability	ACCGCCAAATTTAATTGCAGAGG	PTEN	ENSG00000171862	-0.2720025727342864	[328]	[196]	-2	hSpCas9	negative selection	11574309
87933132	87933155	10	+	28162770	MOLM13	viability	AAAGCTGGAAAGGGACGAACTGG	PTEN	ENSG00000171862	0.3101499185503844	[279]	[250]	2	hSpCas9	negative selection	11574310
87957910	87957933	10	-	28162770	MOLM13	viability	GAACTTGTCTTCCCGTCGTGTGG	PTEN	ENSG00000171862	0.9046604027707041	[279]	[378]	7	hSpCas9	negative selection	11574311
87957899	87957922	10	+	28162770	MOLM13	viability	CAATTCAGGACCCACACGACGGG	PTEN	ENSG00000171862	0.9218783285226306	[675]	[925]	7	hSpCas9	negative selection	11574312
87952177	87952200	10	+	28162770	MOLM13	viability	TCATCTGGATTATAGACCAGTGG	PTEN	ENSG00000171862	1.1604926054537048	[567]	[917]	8	hSpCas9	negative selection	11574313
87933045	87933068	10	-	28162770	MOLM13	viability	GGTTTGATAAGTTCTAGCTGTGG	PTEN	ENSG00000171862	1.7666514918528984	[112]	[277]	9	hSpCas9	negative selection	11574314
87961010	87961033	10	+	28162770	MOLM13	viability	AGAGCGTGCAGATAATGACAAGG	PTEN	ENSG00000171862	-0.8021997818231654	[204]	[84]	-4	hSpCas9	negative selection	11574315
87952235	87952258	10	-	28162770	MOLM13	viability	CAAGTTCCGCCACTGAACATTGG	PTEN	ENSG00000171862	0.8684273111283076	[1224]	[1616]	6	hSpCas9	negative selection	11574316
87864477	87864500	10	-	28162770	MOLM13	viability	GCTAACGATCTCTTTGATGATGG	PTEN	ENSG00000171862	0.014082312101159955	[703]	[513]	0	hSpCas9	negative selection	11574317
87933117	87933140	10	+	28162770	MOLM13	viability	GCAGCAATTCACTGTAAAGCTGG	PTEN	ENSG00000171862	1.0987266248494418	[422]	[654]	8	hSpCas9	negative selection	11574318
87931068	87931091	10	+	28162770	HEL	viability	ACCGCCAAATTTAATTGCAGAGG	PTEN	ENSG00000171862	0.4522768995553499	[282]	[247]	4	hSpCas9	negative selection	11743675
87933132	87933155	10	+	28162770	HEL	viability	AAAGCTGGAAAGGGACGAACTGG	PTEN	ENSG00000171862	0.06096460891024823	[225]	[150]	0	hSpCas9	negative selection	11743676
87957910	87957933	10	-	28162770	HEL	viability	GAACTTGTCTTCCCGTCGTGTGG	PTEN	ENSG00000171862	1.155600284193218	[252]	[360]	8	hSpCas9	negative selection	11743677
87957899	87957922	10	+	28162770	HEL	viability	CAATTCAGGACCCACACGACGGG	PTEN	ENSG00000171862	0.6966511143496503	[498]	[517]	6	hSpCas9	negative selection	11743678
87952177	87952200	10	+	28162770	HEL	viability	TCATCTGGATTATAGACCAGTGG	PTEN	ENSG00000171862	0.2975299132770861	[530]	[417]	2	hSpCas9	negative selection	11743679
87933045	87933068	10	-	28162770	HEL	viability	GGTTTGATAAGTTCTAGCTGTGG	PTEN	ENSG00000171862	0.7026102879777556	[117]	[122]	6	hSpCas9	negative selection	11743680
87961010	87961033	10	+	28162770	HEL	viability	AGAGCGTGCAGATAATGACAAGG	PTEN	ENSG00000171862	-0.6982980858347101	[151]	[59]	-4	hSpCas9	negative selection	11743681
87952235	87952258	10	-	28162770	HEL	viability	CAAGTTCCGCCACTGAACATTGG	PTEN	ENSG00000171862	0.1037371784378438	[1003]	[690]	0	hSpCas9	negative selection	11743682
87864477	87864500	10	-	28162770	HEL	viability	GCTAACGATCTCTTTGATGATGG	PTEN	ENSG00000171862	-0.09885821089749514	[519]	[310]	0	hSpCas9	negative selection	11743683
87933117	87933140	10	+	28162770	HEL	viability	GCAGCAATTCACTGTAAAGCTGG	PTEN	ENSG00000171862	-0.3350995180754843	[322]	[163]	-2	hSpCas9	negative selection	11743684
87931068	87931091	10	+	28162770	MV411	viability	ACCGCCAAATTTAATTGCAGAGG	PTEN	ENSG00000171862	0.052865024269265065	[213]	[186]	0	hSpCas9	negative selection	11913041
87933132	87933155	10	+	28162770	MV411	viability	AAAGCTGGAAAGGGACGAACTGG	PTEN	ENSG00000171862	0.24743755078277532	[202]	[202]	2	hSpCas9	negative selection	11913042
87957910	87957933	10	-	28162770	MV411	viability	GAACTTGTCTTCCCGTCGTGTGG	PTEN	ENSG00000171862	0.5646277266634745	[182]	[227]	5	hSpCas9	negative selection	11913043
87957899	87957922	10	+	28162770	MV411	viability	CAATTCAGGACCCACACGACGGG	PTEN	ENSG00000171862	1.9193833530985713	[412]	[1315]	9	hSpCas9	negative selection	11913044
87952177	87952200	10	+	28162770	MV411	viability	TCATCTGGATTATAGACCAGTGG	PTEN	ENSG00000171862	0.3965809900885846	[403]	[447]	3	hSpCas9	negative selection	11913045
87933045	87933068	10	-	28162770	MV411	viability	GGTTTGATAAGTTCTAGCTGTGG	PTEN	ENSG00000171862	-0.031538398920039956	[90]	[74]	0	hSpCas9	negative selection	11913046
87961010	87961033	10	+	28162770	MV411	viability	AGAGCGTGCAGATAATGACAAGG	PTEN	ENSG00000171862	0.956987687368581	[84]	[138]	8	hSpCas9	negative selection	11913047
87952235	87952258	10	-	28162770	MV411	viability	CAAGTTCCGCCACTGAACATTGG	PTEN	ENSG00000171862	0.34712279615911945	[642]	[688]	3	hSpCas9	negative selection	11913048
87864477	87864500	10	-	28162770	MV411	viability	GCTAACGATCTCTTTGATGATGG	PTEN	ENSG00000171862	0.20921822855228522	[458]	[446]	1	hSpCas9	negative selection	11913049
87933117	87933140	10	+	28162770	MV411	viability	GCAGCAATTCACTGTAAAGCTGG	PTEN	ENSG00000171862	1.7139032888686219	[185]	[513]	9	hSpCas9	negative selection	11913050
87931068	87931091	10	+	28162770	MONOMAC1	viability	ACCGCCAAATTTAATTGCAGAGG	PTEN	ENSG00000171862	0.8430405923157814	[141]	[291]	7	hSpCas9	negative selection	12082407
87933132	87933155	10	+	28162770	MONOMAC1	viability	AAAGCTGGAAAGGGACGAACTGG	PTEN	ENSG00000171862	1.3356311462193897	[102]	[297]	9	hSpCas9	negative selection	12082408
87957910	87957933	10	-	28162770	MONOMAC1	viability	GAACTTGTCTTCCCGTCGTGTGG	PTEN	ENSG00000171862	0.48389471219232466	[125]	[201]	5	hSpCas9	negative selection	12082409
87957899	87957922	10	+	28162770	MONOMAC1	viability	CAATTCAGGACCCACACGACGGG	PTEN	ENSG00000171862	0.5952864618062379	[316]	[548]	6	hSpCas9	negative selection	12082410
87952177	87952200	10	+	28162770	MONOMAC1	viability	TCATCTGGATTATAGACCAGTGG	PTEN	ENSG00000171862	1.185596110648401	[241]	[630]	9	hSpCas9	negative selection	12082411
87933045	87933068	10	-	28162770	MONOMAC1	viability	GGTTTGATAAGTTCTAGCTGTGG	PTEN	ENSG00000171862	1.2312001499741494	[67]	[182]	9	hSpCas9	negative selection	12082412
87961010	87961033	10	+	28162770	MONOMAC1	viability	AGAGCGTGCAGATAATGACAAGG	PTEN	ENSG00000171862	0.11747377626532562	[77]	[96]	1	hSpCas9	negative selection	12082413
87952235	87952258	10	-	28162770	MONOMAC1	viability	CAAGTTCCGCCACTGAACATTGG	PTEN	ENSG00000171862	1.111216310930732	[423]	[1049]	8	hSpCas9	negative selection	12082414
87864477	87864500	10	-	28162770	MONOMAC1	viability	GCTAACGATCTCTTTGATGATGG	PTEN	ENSG00000171862	0.6123572202716492	[302]	[530]	6	hSpCas9	negative selection	12082415
87933117	87933140	10	+	28162770	MONOMAC1	viability	GCAGCAATTCACTGTAAAGCTGG	PTEN	ENSG00000171862	1.401757926841172	[172]	[523]	9	hSpCas9	negative selection	12082416
87931068	87931091	10	+	28162770	OCIAML2	viability	ACCGCCAAATTTAATTGCAGAGG	PTEN	ENSG00000171862	-0.2934368233358098	[43]	[198]	-2	hSpCas9	negative selection	12251773
87933132	87933155	10	+	28162770	OCIAML2	viability	AAAGCTGGAAAGGGACGAACTGG	PTEN	ENSG00000171862	0.5077401587862962	[41]	[330]	5	hSpCas9	negative selection	12251774
87957910	87957933	10	-	28162770	OCIAML2	viability	GAACTTGTCTTCCCGTCGTGTGG	PTEN	ENSG00000171862	1.4272156307633506	[31]	[476]	9	hSpCas9	negative selection	12251775
87957899	87957922	10	+	28162770	OCIAML2	viability	CAATTCAGGACCCACACGACGGG	PTEN	ENSG00000171862	0.7864722503819345	[65]	[630]	7	hSpCas9	negative selection	12251776
87952177	87952200	10	+	28162770	OCIAML2	viability	TCATCTGGATTATAGACCAGTGG	PTEN	ENSG00000171862	0.4698133300773837	[101]	[782]	4	hSpCas9	negative selection	12251777
87933045	87933068	10	-	28162770	OCIAML2	viability	GGTTTGATAAGTTCTAGCTGTGG	PTEN	ENSG00000171862	0.37736708131278895	[9]	[71]	3	hSpCas9	negative selection	12251778
87961010	87961033	10	+	28162770	OCIAML2	viability	AGAGCGTGCAGATAATGACAAGG	PTEN	ENSG00000171862	1.0257960008773377	[20]	[236]	8	hSpCas9	negative selection	12251779
87952235	87952258	10	-	28162770	OCIAML2	viability	CAAGTTCCGCCACTGAACATTGG	PTEN	ENSG00000171862	0.9245236413846023	[120]	[1272]	8	hSpCas9	negative selection	12251780
87864477	87864500	10	-	28162770	OCIAML2	viability	GCTAACGATCTCTTTGATGATGG	PTEN	ENSG00000171862	0.3695897307210695	[61]	[443]	3	hSpCas9	negative selection	12251781
87933117	87933140	10	+	28162770	OCIAML2	viability	GCAGCAATTCACTGTAAAGCTGG	PTEN	ENSG00000171862	0.6094345636870178	[45]	[388]	6	hSpCas9	negative selection	12251782
87931068	87931091	10	+	28162770	OCIAML3	viability	ACCGCCAAATTTAATTGCAGAGG	PTEN	ENSG00000171862	4.062037958458475	[65]	[3327]	9	hSpCas9	negative selection	12421139
87933132	87933155	10	+	28162770	OCIAML3	viability	AAAGCTGGAAAGGGACGAACTGG	PTEN	ENSG00000171862	3.656151420418005	[50]	[1940]	9	hSpCas9	negative selection	12421140
87957910	87957933	10	-	28162770	OCIAML3	viability	GAACTTGTCTTCCCGTCGTGTGG	PTEN	ENSG00000171862	3.3608831081222763	[66]	[2077]	9	hSpCas9	negative selection	12421141
87957899	87957922	10	+	28162770	OCIAML3	viability	CAATTCAGGACCCACACGACGGG	PTEN	ENSG00000171862	4.521903014094943	[95]	[6657]	9	hSpCas9	negative selection	12421142
87952177	87952200	10	+	28162770	OCIAML3	viability	TCATCTGGATTATAGACCAGTGG	PTEN	ENSG00000171862	4.256096929192778	[132]	[7671]	9	hSpCas9	negative selection	12421143
87933045	87933068	10	-	28162770	OCIAML3	viability	GGTTTGATAAGTTCTAGCTGTGG	PTEN	ENSG00000171862	5.210123380859154	[27]	[3128]	9	hSpCas9	negative selection	12421144
87961010	87961033	10	+	28162770	OCIAML3	viability	AGAGCGTGCAGATAATGACAAGG	PTEN	ENSG00000171862	3.461274795177027	[35]	[1196]	9	hSpCas9	negative selection	12421145
87952235	87952258	10	-	28162770	OCIAML3	viability	CAAGTTCCGCCACTGAACATTGG	PTEN	ENSG00000171862	4.459906014200641	[221]	[14748]	9	hSpCas9	negative selection	12421146
87864477	87864500	10	-	28162770	OCIAML3	viability	GCTAACGATCTCTTTGATGATGG	PTEN	ENSG00000171862	3.761196609437498	[119]	[4911]	9	hSpCas9	negative selection	12421147
87933117	87933140	10	+	28162770	OCIAML3	viability	GCAGCAATTCACTGTAAAGCTGG	PTEN	ENSG00000171862	4.927832151542939	[81]	[7534]	9	hSpCas9	negative selection	12421148