Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:5894
• Symbol:RAF1
• Description:Raf-1 proto-oncogene, serine/threonine kinase

DataSource: http://genomecrispr.dkfz.de/#!/results/RAF1

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
12618514	12618537	3	-	26472758	Jiyoye	viability	GCCGAACAAGCAAAGAACAGTGG	RAF1	ENSG00000132155	0.5082615066201877	[123]	[132]	4	hSpCas9	negative selection	133190
12618641	12618664	3	+	26472758	Jiyoye	viability	GCAGCTGGAGCCATCAAACACGG	RAF1	ENSG00000132155	-0.39809622605124173	[345]	[197]	-3	hSpCas9	negative selection	133191
12590891	12590914	3	-	26472758	Jiyoye	viability	ATTGTGACCCAGTGGTGCGAGGG	RAF1	ENSG00000132155	1.0155968550510186	[121]	[185]	6	hSpCas9	negative selection	133192
12618681	12618704	3	-	26472758	Jiyoye	viability	GCTTGGAAGACGATCAGCAATGG	RAF1	ENSG00000132155	0.426284204453578	[74]	[75]	3	hSpCas9	negative selection	133193
12612002	12612025	3	-	26472758	Jiyoye	viability	TATGAAAGCACTCAAGGTGAGGG	RAF1	ENSG00000132155	0.20554152033622303	[137]	[119]	1	hSpCas9	negative selection	133194
12604214	12604237	3	+	26472758	Jiyoye	viability	GGAGAGGGAACCTTCAGATGAGG	RAF1	ENSG00000132155	0.3222864839193602	[419]	[395]	2	hSpCas9	negative selection	133195
12604172	12604195	3	+	26472758	Jiyoye	viability	GACCATGTGGACATTAGGTGTGG	RAF1	ENSG00000132155	-0.4659125060119072	[173]	[94]	-3	hSpCas9	negative selection	133196
12600187	12600210	3	-	26472758	Jiyoye	viability	CGTGCCAGCACAAAGAGAGCGGG	RAF1	ENSG00000132155	-0.5210339354261162	[195]	[102]	-4	hSpCas9	negative selection	133197
12591718	12591741	3	-	26472758	Jiyoye	viability	CCAGGCCTTCAGGAATGAGGTGG	RAF1	ENSG00000132155	-1.1517919106823382	[164]	[55]	-7	hSpCas9	negative selection	133198
12585244	12585267	3	-	26472758	Jiyoye	viability	GTGATACATGTAGGCCCCAGAGG	RAF1	ENSG00000132155	-0.5128025350629215	[262]	[138]	-4	hSpCas9	negative selection	133199
12618514	12618537	3	-	26472758	KBM7	viability	GCCGAACAAGCAAAGAACAGTGG	RAF1	ENSG00000132155	-1.363640223171079	[423,428]	[99,58]	-7	hSpCas9	negative selection	324308
12618641	12618664	3	+	26472758	KBM7	viability	GCAGCTGGAGCCATCAAACACGG	RAF1	ENSG00000132155	-0.10021478627019109	[706,780]	[308,347]	-1	hSpCas9	negative selection	324309
12590891	12590914	3	-	26472758	KBM7	viability	ATTGTGACCCAGTGGTGCGAGGG	RAF1	ENSG00000132155	-1.8857272858023446	[777,619]	[62,110]	-8	hSpCas9	negative selection	324310
12618681	12618704	3	-	26472758	KBM7	viability	GCTTGGAAGACGATCAGCAATGG	RAF1	ENSG00000132155	0.2811098245548127	[298,268]	[224,105]	3	hSpCas9	negative selection	324311
12612002	12612025	3	-	26472758	KBM7	viability	TATGAAAGCACTCAAGGTGAGGG	RAF1	ENSG00000132155	-1.2274270789963684	[510,345]	[107,63]	-7	hSpCas9	negative selection	324312
12604214	12604237	3	+	26472758	KBM7	viability	GGAGAGGGAACCTTCAGATGAGG	RAF1	ENSG00000132155	-0.668278798598557	[2017,1159]	[554,373]	-5	hSpCas9	negative selection	324313
12604172	12604195	3	+	26472758	KBM7	viability	GACCATGTGGACATTAGGTGTGG	RAF1	ENSG00000132155	-0.23768017538711966	[469,508]	[282,119]	-2	hSpCas9	negative selection	324314
12600187	12600210	3	-	26472758	KBM7	viability	CGTGCCAGCACAAAGAGAGCGGG	RAF1	ENSG00000132155	-0.591136309504475	[507,587]	[141,200]	-5	hSpCas9	negative selection	324315
12591718	12591741	3	-	26472758	KBM7	viability	CCAGGCCTTCAGGAATGAGGTGG	RAF1	ENSG00000132155	-1.3937211274823023	[436,168]	[41,60]	-7	hSpCas9	negative selection	324316
12585244	12585267	3	-	26472758	KBM7	viability	GTGATACATGTAGGCCCCAGAGG	RAF1	ENSG00000132155	-1.1886653246654222	[522,555]	[89,131]	-7	hSpCas9	negative selection	324317
12618514	12618537	3	-	26472758	Raji	viability	GCCGAACAAGCAAAGAACAGTGG	RAF1	ENSG00000132155	0.6686417755034872	[224]	[82]	6	hSpCas9	negative selection	515426
12618641	12618664	3	+	26472758	Raji	viability	GCAGCTGGAGCCATCAAACACGG	RAF1	ENSG00000132155	0.34325218896651144	[410]	[120]	3	hSpCas9	negative selection	515427
12590891	12590914	3	-	26472758	Raji	viability	ATTGTGACCCAGTGGTGCGAGGG	RAF1	ENSG00000132155	0.1203225910810975	[221]	[55]	1	hSpCas9	negative selection	515428
12618681	12618704	3	-	26472758	Raji	viability	GCTTGGAAGACGATCAGCAATGG	RAF1	ENSG00000132155	-0.06770317118449187	[139]	[30]	0	hSpCas9	negative selection	515429
12612002	12612025	3	-	26472758	Raji	viability	TATGAAAGCACTCAAGGTGAGGG	RAF1	ENSG00000132155	-0.20909012942165472	[263]	[52]	-2	hSpCas9	negative selection	515430
12604214	12604237	3	+	26472758	Raji	viability	GGAGAGGGAACCTTCAGATGAGG	RAF1	ENSG00000132155	0.1377571844171186	[704]	[179]	1	hSpCas9	negative selection	515431
12604172	12604195	3	+	26472758	Raji	viability	GACCATGTGGACATTAGGTGTGG	RAF1	ENSG00000132155	-0.7048701860968436	[294]	[41]	-5	hSpCas9	negative selection	515432
12600187	12600210	3	-	26472758	Raji	viability	CGTGCCAGCACAAAGAGAGCGGG	RAF1	ENSG00000132155	0.03002465266735979	[248]	[58]	0	hSpCas9	negative selection	515433
12591718	12591741	3	-	26472758	Raji	viability	CCAGGCCTTCAGGAATGAGGTGG	RAF1	ENSG00000132155	-0.7318202527233445	[228]	[31]	-5	hSpCas9	negative selection	515434
12585244	12585267	3	-	26472758	Raji	viability	GTGATACATGTAGGCCCCAGAGG	RAF1	ENSG00000132155	-0.014606989005010895	[369]	[84]	0	hSpCas9	negative selection	515435
12618514	12618537	3	-	26472758	K562	viability	GCCGAACAAGCAAAGAACAGTGG	RAF1	ENSG00000132155	-3.8848642892785197	[524]	[29]	-9	hSpCas9	negative selection	706544
12618641	12618664	3	+	26472758	K562	viability	GCAGCTGGAGCCATCAAACACGG	RAF1	ENSG00000132155	-1.0290108495297254	[584]	[241]	-5	hSpCas9	negative selection	706545
12590891	12590914	3	-	26472758	K562	viability	ATTGTGACCCAGTGGTGCGAGGG	RAF1	ENSG00000132155	-1.5386143226484235	[646]	[187]	-6	hSpCas9	negative selection	706546
12618681	12618704	3	-	26472758	K562	viability	GCTTGGAAGACGATCAGCAATGG	RAF1	ENSG00000132155	-0.6378277408414135	[340]	[184]	-4	hSpCas9	negative selection	706547
12612002	12612025	3	-	26472758	K562	viability	TATGAAAGCACTCAAGGTGAGGG	RAF1	ENSG00000132155	-2.2208735423920927	[369]	[66]	-7	hSpCas9	negative selection	706548
12604214	12604237	3	+	26472758	K562	viability	GGAGAGGGAACCTTCAGATGAGG	RAF1	ENSG00000132155	-1.6693802372842494	[1412]	[374]	-7	hSpCas9	negative selection	706549
12604172	12604195	3	+	26472758	K562	viability	GACCATGTGGACATTAGGTGTGG	RAF1	ENSG00000132155	-0.20923208301904272	[466]	[340]	-1	hSpCas9	negative selection	706550
12600187	12600210	3	-	26472758	K562	viability	CGTGCCAGCACAAAGAGAGCGGG	RAF1	ENSG00000132155	-0.2652021402693199	[456]	[320]	-2	hSpCas9	negative selection	706551
12591718	12591741	3	-	26472758	K562	viability	CCAGGCCTTCAGGAATGAGGTGG	RAF1	ENSG00000132155	-2.9685749956677516	[305]	[32]	-8	hSpCas9	negative selection	706552
12585244	12585267	3	-	26472758	K562	viability	GTGATACATGTAGGCCCCAGAGG	RAF1	ENSG00000132155	-1.5148739536170228	[368]	[108]	-6	hSpCas9	negative selection	706553
12590899	12590922	3	-	26627737	DLD1	viability	ACCTGGCAATTGTGACCCAGTGG	RAF1	ENSG00000132155	-0.9871091156825375	[413]	[69,44,77]	-7	hSpCas9	negative selection	819290
12600187	12600210	3	-	26627737	DLD1	viability	CGTGCCAGCACAAAGAGAGCGGG	RAF1	ENSG00000132155	-1.0382089413116704	[726]	[135,96,99]	-7	hSpCas9	negative selection	819294
12603510	12603533	3	-	26627737	DLD1	viability	CAACCTGAGTGCTTCTCCCAGGG	RAF1	ENSG00000132155	-0.871259600443363	[673]	[146,69,124]	-7	hSpCas9	negative selection	819297
12604220	12604243	3	+	26627737	DLD1	viability	GGAACCTTCAGATGAGGGACTGG	RAF1	ENSG00000132155	-1.1909716582888015	[322]	[70,36,26]	-8	hSpCas9	negative selection	819300
12608851	12608874	3	+	26627737	DLD1	viability	GACATCGAAATCCATTGAGCAGG	RAF1	ENSG00000132155	-0.2674247296909653	[236]	[63,20,92]	-3	hSpCas9	negative selection	819301
12618599	12618622	3	-	26627737	DLD1	viability	AGCAGTTTGGCTATCAGCGCCGG	RAF1	ENSG00000132155	-0.7315368911634401	[585]	[75,78,165]	-6	hSpCas9	negative selection	819303
12590899	12590922	3	-	26627737	GBM cells	viability after 5 days	ACCTGGCAATTGTGACCCAGTGG	RAF1	ENSG00000132155	0.23333291395624473	[160]	[124,77]	3	hSpCas9	negative selection	901605
12600187	12600210	3	-	26627737	GBM cells	viability after 5 days	CGTGCCAGCACAAAGAGAGCGGG	RAF1	ENSG00000132155	-0.6719390264200348	[406]	[116,156]	-8	hSpCas9	negative selection	901609
12603510	12603533	3	-	26627737	GBM cells	viability after 5 days	CAACCTGAGTGCTTCTCCCAGGG	RAF1	ENSG00000132155	-0.6043648282417624	[308]	[138,78]	-7	hSpCas9	negative selection	901612
12604220	12604243	3	+	26627737	GBM cells	viability after 5 days	GGAACCTTCAGATGAGGGACTGG	RAF1	ENSG00000132155	-0.13503345703765224	[171]	[72,94]	-2	hSpCas9	negative selection	901615
12608851	12608874	3	+	26627737	GBM cells	viability after 5 days	GACATCGAAATCCATTGAGCAGG	RAF1	ENSG00000132155	0.9054567207524575	[109]	[127,92]	9	hSpCas9	negative selection	901616
12618599	12618622	3	-	26627737	GBM cells	viability after 5 days	AGCAGTTTGGCTATCAGCGCCGG	RAF1	ENSG00000132155	0.41172658985100646	[245]	[184,165]	6	hSpCas9	negative selection	901618
12590899	12590922	3	-	26627737	GBM cells	viability after 13 days	ACCTGGCAATTGTGACCCAGTGG	RAF1	ENSG00000132155	-0.7962850811022834	[160]	[30,65]	-7	hSpCas9	negative selection	983920
12600187	12600210	3	-	26627737	GBM cells	viability after 13 days	CGTGCCAGCACAAAGAGAGCGGG	RAF1	ENSG00000132155	-0.6999431574705082	[406]	[157,117]	-7	hSpCas9	negative selection	983924
12603510	12603533	3	-	26627737	GBM cells	viability after 13 days	CAACCTGAGTGCTTCTCCCAGGG	RAF1	ENSG00000132155	-0.14541590480083935	[308]	[214,99]	-2	hSpCas9	negative selection	983927
12604220	12604243	3	+	26627737	GBM cells	viability after 13 days	GGAACCTTCAGATGAGGGACTGG	RAF1	ENSG00000132155	-0.44473646234402764	[171]	[99,42]	-5	hSpCas9	negative selection	983930
12608851	12608874	3	+	26627737	GBM cells	viability after 13 days	GACATCGAAATCCATTGAGCAGG	RAF1	ENSG00000132155	1.0344340650060215	[109]	[140,106]	9	hSpCas9	negative selection	983931
12618599	12618622	3	-	26627737	GBM cells	viability after 13 days	AGCAGTTTGGCTATCAGCGCCGG	RAF1	ENSG00000132155	0.05003354472522231	[245]	[162,117]	0	hSpCas9	negative selection	983933
12590899	12590922	3	-	26627737	GBM cells	viability after 21 days	ACCTGGCAATTGTGACCCAGTGG	RAF1	ENSG00000132155	-2.941128480435825	[160]	[13,8]	-9	hSpCas9	negative selection	1066235
12600187	12600210	3	-	26627737	GBM cells	viability after 21 days	CGTGCCAGCACAAAGAGAGCGGG	RAF1	ENSG00000132155	-0.19494933436527306	[406]	[200,185]	-2	hSpCas9	negative selection	1066239
12603510	12603533	3	-	26627737	GBM cells	viability after 21 days	CAACCTGAGTGCTTCTCCCAGGG	RAF1	ENSG00000132155	-0.571760229886296	[308]	[125,100]	-5	hSpCas9	negative selection	1066242
12604220	12604243	3	+	26627737	GBM cells	viability after 21 days	GGAACCTTCAGATGAGGGACTGG	RAF1	ENSG00000132155	-0.3257875003285686	[171]	[84,64]	-3	hSpCas9	negative selection	1066245
12608851	12608874	3	+	26627737	GBM cells	viability after 21 days	GACATCGAAATCCATTGAGCAGG	RAF1	ENSG00000132155	0.6678852663248259	[109]	[107,82]	6	hSpCas9	negative selection	1066246
12618599	12618622	3	-	26627737	GBM cells	viability after 21 days	AGCAGTTTGGCTATCAGCGCCGG	RAF1	ENSG00000132155	0.36835718840528686	[245]	[171,172]	4	hSpCas9	negative selection	1066248
12590899	12590922	3	-	26627737	RPE1	viability after 9 days	ACCTGGCAATTGTGACCCAGTGG	RAF1	ENSG00000132155	-3.251908167853415	[299]	[1,19]	-9	hSpCas9	negative selection	1148550
12600187	12600210	3	-	26627737	RPE1	viability after 9 days	CGTGCCAGCACAAAGAGAGCGGG	RAF1	ENSG00000132155	-2.036907909441184	[1756]	[61,226]	-8	hSpCas9	negative selection	1148554
12603510	12603533	3	-	26627737	RPE1	viability after 9 days	CAACCTGAGTGCTTCTCCCAGGG	RAF1	ENSG00000132155	-1.68497958996252	[321]	[50,5]	-8	hSpCas9	negative selection	1148557
12604220	12604243	3	+	26627737	RPE1	viability after 9 days	GGAACCTTCAGATGAGGGACTGG	RAF1	ENSG00000132155	-0.3730805079275949	[748]	[146,224]	-3	hSpCas9	negative selection	1148560
12608851	12608874	3	+	26627737	RPE1	viability after 9 days	GACATCGAAATCCATTGAGCAGG	RAF1	ENSG00000132155	-4.191425270866275	[673]	[4,19]	-9	hSpCas9	negative selection	1148561
12618599	12618622	3	-	26627737	RPE1	viability after 9 days	AGCAGTTTGGCTATCAGCGCCGG	RAF1	ENSG00000132155	-0.15388618140063937	[1191]	[265,424]	-1	hSpCas9	negative selection	1148563
12590899	12590922	3	-	26627737	RPE1	viability after 12 days	ACCTGGCAATTGTGACCCAGTGG	RAF1	ENSG00000132155	-4.7754897685844915	[299]	[0,4]	-9	hSpCas9	negative selection	1230865
12600187	12600210	3	-	26627737	RPE1	viability after 12 days	CGTGCCAGCACAAAGAGAGCGGG	RAF1	ENSG00000132155	-4.322072109860759	[1756]	[26,19]	-9	hSpCas9	negative selection	1230869
12603510	12603533	3	-	26627737	RPE1	viability after 12 days	CAACCTGAGTGCTTCTCCCAGGG	RAF1	ENSG00000132155	-6.43480546644148	[321]	[0,0]	-9	hSpCas9	negative selection	1230872
12604220	12604243	3	+	26627737	RPE1	viability after 12 days	GGAACCTTCAGATGAGGGACTGG	RAF1	ENSG00000132155	-0.9562396808474666	[748]	[76,131]	-6	hSpCas9	negative selection	1230875
12608851	12608874	3	+	26627737	RPE1	viability after 12 days	GACATCGAAATCCATTGAGCAGG	RAF1	ENSG00000132155	-5.943275859270469	[673]	[0,4]	-9	hSpCas9	negative selection	1230876
12618599	12618622	3	-	26627737	RPE1	viability after 12 days	AGCAGTTTGGCTATCAGCGCCGG	RAF1	ENSG00000132155	-1.1292853653923438	[1191]	[57,239]	-7	hSpCas9	negative selection	1230878
12590899	12590922	3	-	26627737	RPE1	viability after 15 days	ACCTGGCAATTGTGACCCAGTGG	RAF1	ENSG00000132155	-3.146826121795857	[299]	[4,13]	-9	hSpCas9	negative selection	1313180
12600187	12600210	3	-	26627737	RPE1	viability after 15 days	CGTGCCAGCACAAAGAGAGCGGG	RAF1	ENSG00000132155	-4.222838461416253	[1756]	[19,32]	-9	hSpCas9	negative selection	1313184
12603510	12603533	3	-	26627737	RPE1	viability after 15 days	CAACCTGAGTGCTTCTCCCAGGG	RAF1	ENSG00000132155	-2.6022774086342038	[321]	[14,14]	-8	hSpCas9	negative selection	1313187
12604220	12604243	3	+	26627737	RPE1	viability after 15 days	GGAACCTTCAGATGAGGGACTGG	RAF1	ENSG00000132155	-1.2029080711894498	[748]	[117,66]	-6	hSpCas9	negative selection	1313190
12608851	12608874	3	+	26627737	RPE1	viability after 15 days	GACATCGAAATCCATTGAGCAGG	RAF1	ENSG00000132155	-7.574855907309964	[673]	[0,0]	-9	hSpCas9	negative selection	1313191
12618599	12618622	3	-	26627737	RPE1	viability after 15 days	AGCAGTTTGGCTATCAGCGCCGG	RAF1	ENSG00000132155	-0.8848623913849603	[1191]	[204,160]	-5	hSpCas9	negative selection	1313193
12590899	12590922	3	-	26627737	RPE1	viability after 18 days	ACCTGGCAATTGTGACCCAGTGG	RAF1	ENSG00000132155	-3.5987701718161675	[299]	[11,0]	-9	hSpCas9	negative selection	1395495
12600187	12600210	3	-	26627737	RPE1	viability after 18 days	CGTGCCAGCACAAAGAGAGCGGG	RAF1	ENSG00000132155	-4.191422673356919	[1756]	[9,42]	-9	hSpCas9	negative selection	1395499
12603510	12603533	3	-	26627737	RPE1	viability after 18 days	CAACCTGAGTGCTTCTCCCAGGG	RAF1	ENSG00000132155	-6.441248618013875	[321]	[0,0]	-9	hSpCas9	negative selection	1395502
12604220	12604243	3	+	26627737	RPE1	viability after 18 days	GGAACCTTCAGATGAGGGACTGG	RAF1	ENSG00000132155	-0.9736492053373179	[748]	[129,73]	-6	hSpCas9	negative selection	1395505
12608851	12608874	3	+	26627737	RPE1	viability after 18 days	GACATCGAAATCCATTGAGCAGG	RAF1	ENSG00000132155	-5.008867189326139	[673]	[9,0]	-9	hSpCas9	negative selection	1395506
12618599	12618622	3	-	26627737	RPE1	viability after 18 days	AGCAGTTTGGCTATCAGCGCCGG	RAF1	ENSG00000132155	-1.8803613967319555	[1191]	[141,28]	-8	hSpCas9	negative selection	1395508
12590899	12590922	3	-	26627737	HeLa	viability after 8 days	ACCTGGCAATTGTGACCCAGTGG	RAF1	ENSG00000132155	0.7017835185357804	[225]	[69,332,63]	6	hSpCas9	negative selection	1477810
12600187	12600210	3	-	26627737	HeLa	viability after 8 days	CGTGCCAGCACAAAGAGAGCGGG	RAF1	ENSG00000132155	0.4768635259385835	[617]	[303,246,543]	4	hSpCas9	negative selection	1477814
12603510	12603533	3	-	26627737	HeLa	viability after 8 days	CAACCTGAGTGCTTCTCCCAGGG	RAF1	ENSG00000132155	1.5419444512304876	[113]	[380,42,66]	9	hSpCas9	negative selection	1477817
12604220	12604243	3	+	26627737	HeLa	viability after 8 days	GGAACCTTCAGATGAGGGACTGG	RAF1	ENSG00000132155	0.8292042684278053	[331]	[287,203,282]	6	hSpCas9	negative selection	1477820
12608851	12608874	3	+	26627737	HeLa	viability after 8 days	GACATCGAAATCCATTGAGCAGG	RAF1	ENSG00000132155	-0.06587657343785025	[223]	[62,90,116]	0	hSpCas9	negative selection	1477821
12618599	12618622	3	-	26627737	HeLa	viability after 8 days	AGCAGTTTGGCTATCAGCGCCGG	RAF1	ENSG00000132155	0.4706226268889999	[341]	[260,241,132]	4	hSpCas9	negative selection	1477823
12590899	12590922	3	-	26627737	HeLa	viability after 12 days	ACCTGGCAATTGTGACCCAGTGG	RAF1	ENSG00000132155	0.6668126653067646	[225]	[191,101,156]	5	hSpCas9	negative selection	1560125
12600187	12600210	3	-	26627737	HeLa	viability after 12 days	CGTGCCAGCACAAAGAGAGCGGG	RAF1	ENSG00000132155	0.4021803266483458	[617]	[357,366,284]	3	hSpCas9	negative selection	1560129
12603510	12603533	3	-	26627737	HeLa	viability after 12 days	CAACCTGAGTGCTTCTCCCAGGG	RAF1	ENSG00000132155	1.0878668532228057	[113]	[25,130,137]	7	hSpCas9	negative selection	1560132
12604220	12604243	3	+	26627737	HeLa	viability after 12 days	GGAACCTTCAGATGAGGGACTGG	RAF1	ENSG00000132155	-0.5601311673224681	[331]	[121,45,116]	-5	hSpCas9	negative selection	1560135
12608851	12608874	3	+	26627737	HeLa	viability after 12 days	GACATCGAAATCCATTGAGCAGG	RAF1	ENSG00000132155	-0.434221342030783	[223]	[55,88,57]	-4	hSpCas9	negative selection	1560136
12618599	12618622	3	-	26627737	HeLa	viability after 12 days	AGCAGTTTGGCTATCAGCGCCGG	RAF1	ENSG00000132155	0.9881191702860376	[341]	[276,213,356]	7	hSpCas9	negative selection	1560138
12590899	12590922	3	-	26627737	HeLa	viability after 15 days	ACCTGGCAATTGTGACCCAGTGG	RAF1	ENSG00000132155	-0.367339159619648	[225]	[83,31,99]	-3	hSpCas9	negative selection	1642440
12600187	12600210	3	-	26627737	HeLa	viability after 15 days	CGTGCCAGCACAAAGAGAGCGGG	RAF1	ENSG00000132155	0.08116119920217035	[617]	[133,268,407]	0	hSpCas9	negative selection	1642444
12603510	12603533	3	-	26627737	HeLa	viability after 15 days	CAACCTGAGTGCTTCTCCCAGGG	RAF1	ENSG00000132155	1.8616544578732372	[113]	[129,249,122]	9	hSpCas9	negative selection	1642447
12604220	12604243	3	+	26627737	HeLa	viability after 15 days	GGAACCTTCAGATGAGGGACTGG	RAF1	ENSG00000132155	-0.092107882791546	[331]	[248,24,102]	-1	hSpCas9	negative selection	1642450
12608851	12608874	3	+	26627737	HeLa	viability after 15 days	GACATCGAAATCCATTGAGCAGG	RAF1	ENSG00000132155	0.3940015402083096	[223]	[146,105,104]	3	hSpCas9	negative selection	1642451
12618599	12618622	3	-	26627737	HeLa	viability after 15 days	AGCAGTTTGGCTATCAGCGCCGG	RAF1	ENSG00000132155	0.9200763176146449	[341]	[203,300,287]	7	hSpCas9	negative selection	1642453
12590899	12590922	3	-	26627737	HeLa	viability after 18 days	ACCTGGCAATTGTGACCCAGTGG	RAF1	ENSG00000132155	-0.3689908543070921	[225]	[54,27,99]	-3	hSpCas9	negative selection	1724755
12600187	12600210	3	-	26627737	HeLa	viability after 18 days	CGTGCCAGCACAAAGAGAGCGGG	RAF1	ENSG00000132155	0.060105661404863286	[617]	[86,216,407]	0	hSpCas9	negative selection	1724759
12603510	12603533	3	-	26627737	HeLa	viability after 18 days	CAACCTGAGTGCTTCTCCCAGGG	RAF1	ENSG00000132155	1.8473764192369304	[113]	[79,211,122]	9	hSpCas9	negative selection	1724762
12604220	12604243	3	+	26627737	HeLa	viability after 18 days	GGAACCTTCAGATGAGGGACTGG	RAF1	ENSG00000132155	-0.10286075094178057	[331]	[164,20,102]	-1	hSpCas9	negative selection	1724765
12608851	12608874	3	+	26627737	HeLa	viability after 18 days	GACATCGAAATCCATTGAGCAGG	RAF1	ENSG00000132155	0.4097065145888848	[223]	[92,97,104]	3	hSpCas9	negative selection	1724766
12618599	12618622	3	-	26627737	HeLa	viability after 18 days	AGCAGTTTGGCTATCAGCGCCGG	RAF1	ENSG00000132155	0.9028971631086197	[341]	[130,248,287]	6	hSpCas9	negative selection	1724768
12590899	12590922	3	-	26627737	HCT116	viability after 6 days	ACCTGGCAATTGTGACCCAGTGG	RAF1	ENSG00000132155	-2.5099451526903476	[152]	[0,5]	-8	hSpCas9	negative selection	1807070
12600187	12600210	3	-	26627737	HCT116	viability after 6 days	CGTGCCAGCACAAAGAGAGCGGG	RAF1	ENSG00000132155	0.3295144794596393	[1106]	[121,271]	1	hSpCas9	negative selection	1807074
12603510	12603533	3	-	26627737	HCT116	viability after 6 days	CAACCTGAGTGCTTCTCCCAGGG	RAF1	ENSG00000132155	-1.7042124606088227	[867]	[115,0]	-7	hSpCas9	negative selection	1807077
12604220	12604243	3	+	26627737	HCT116	viability after 6 days	GGAACCTTCAGATGAGGGACTGG	RAF1	ENSG00000132155	0.7088267378675821	[382]	[22,139]	4	hSpCas9	negative selection	1807080
12608851	12608874	3	+	26627737	HCT116	viability after 6 days	GACATCGAAATCCATTGAGCAGG	RAF1	ENSG00000132155	2.412690080756591	[182]	[245,101]	9	hSpCas9	negative selection	1807081
12618599	12618622	3	-	26627737	HCT116	viability after 6 days	AGCAGTTTGGCTATCAGCGCCGG	RAF1	ENSG00000132155	-1.180127786228697	[832]	[109,28]	-6	hSpCas9	negative selection	1807083
12590899	12590922	3	-	26627737	HCT116	viability after 8 days	ACCTGGCAATTGTGACCCAGTGG	RAF1	ENSG00000132155	-2.2324127586667855	[129]	[25,10,8]	-9	hSpCas9	negative selection	1889385
12600187	12600210	3	-	26627737	HCT116	viability after 8 days	CGTGCCAGCACAAAGAGAGCGGG	RAF1	ENSG00000132155	-1.4535802763299273	[515]	[65,77,165]	-9	hSpCas9	negative selection	1889389
12603510	12603533	3	-	26627737	HCT116	viability after 8 days	CAACCTGAGTGCTTCTCCCAGGG	RAF1	ENSG00000132155	-0.6889975472693671	[318]	[115,83,126]	-7	hSpCas9	negative selection	1889392
12604220	12604243	3	+	26627737	HCT116	viability after 8 days	GGAACCTTCAGATGAGGGACTGG	RAF1	ENSG00000132155	-0.41587931830926905	[279]	[50,113,179]	-5	hSpCas9	negative selection	1889395
12608851	12608874	3	+	26627737	HCT116	viability after 8 days	GACATCGAAATCCATTGAGCAGG	RAF1	ENSG00000132155	-0.7716779250737027	[233]	[132,51,42]	-7	hSpCas9	negative selection	1889396
12618599	12618622	3	-	26627737	HCT116	viability after 8 days	AGCAGTTTGGCTATCAGCGCCGG	RAF1	ENSG00000132155	-2.1341028746966817	[755]	[106,89,87]	-9	hSpCas9	negative selection	1889398
12590899	12590922	3	-	26627737	HCT116	viability after 9 days	ACCTGGCAATTGTGACCCAGTGG	RAF1	ENSG00000132155	-3.6710804667228913	[152]	[5,0]	-9	hSpCas9	negative selection	1971700
12600187	12600210	3	-	26627737	HCT116	viability after 9 days	CGTGCCAGCACAAAGAGAGCGGG	RAF1	ENSG00000132155	-2.447036920348336	[1106]	[56,51]	-9	hSpCas9	negative selection	1971704
12603510	12603533	3	-	26627737	HCT116	viability after 9 days	CAACCTGAGTGCTTCTCCCAGGG	RAF1	ENSG00000132155	-4.794551758815586	[867]	[4,10]	-9	hSpCas9	negative selection	1971707
12604220	12604243	3	+	26627737	HCT116	viability after 9 days	GGAACCTTCAGATGAGGGACTGG	RAF1	ENSG00000132155	0.3085797235000195	[382]	[24,206]	2	hSpCas9	negative selection	1971710
12608851	12608874	3	+	26627737	HCT116	viability after 9 days	GACATCGAAATCCATTGAGCAGG	RAF1	ENSG00000132155	0.6511731212696574	[182]	[83,70]	5	hSpCas9	negative selection	1971711
12618599	12618622	3	-	26627737	HCT116	viability after 9 days	AGCAGTTTGGCTATCAGCGCCGG	RAF1	ENSG00000132155	-1.101249234622898	[832]	[39,153]	-7	hSpCas9	negative selection	1971713
12590899	12590922	3	-	26627737	HCT116	viability after 12 days	ACCTGGCAATTGTGACCCAGTGG	RAF1	ENSG00000132155	-3.2591994382641687	[129]	[11,7,0]	-9	hSpCas9	negative selection	2054015
12600187	12600210	3	-	26627737	HCT116	viability after 12 days	CGTGCCAGCACAAAGAGAGCGGG	RAF1	ENSG00000132155	-2.75264279942814	[515]	[60,44,12]	-9	hSpCas9	negative selection	2054019
12603510	12603533	3	-	26627737	HCT116	viability after 12 days	CAACCTGAGTGCTTCTCCCAGGG	RAF1	ENSG00000132155	-1.1966128733829875	[318]	[80,83,53]	-8	hSpCas9	negative selection	2054022
12604220	12604243	3	+	26627737	HCT116	viability after 12 days	GGAACCTTCAGATGAGGGACTGG	RAF1	ENSG00000132155	-1.4702551089836304	[279]	[23,57,79]	-9	hSpCas9	negative selection	2054025
12608851	12608874	3	+	26627737	HCT116	viability after 12 days	GACATCGAAATCCATTGAGCAGG	RAF1	ENSG00000132155	0.09305507878938712	[233]	[185,102,98]	1	hSpCas9	negative selection	2054026
12618599	12618622	3	-	26627737	HCT116	viability after 12 days	AGCAGTTTGGCTATCAGCGCCGG	RAF1	ENSG00000132155	-1.6812922408101443	[755]	[165,43,155]	-9	hSpCas9	negative selection	2054028
12590899	12590922	3	-	26627737	HCT116	viability after 15 days	ACCTGGCAATTGTGACCCAGTGG	RAF1	ENSG00000132155	-4.065314511438039	[129]	[0,10,0]	-9	hSpCas9	negative selection	2136330
12600187	12600210	3	-	26627737	HCT116	viability after 15 days	CGTGCCAGCACAAAGAGAGCGGG	RAF1	ENSG00000132155	-3.26223133478567	[515]	[71,22,2]	-9	hSpCas9	negative selection	2136334
12603510	12603533	3	-	26627737	HCT116	viability after 15 days	CAACCTGAGTGCTTCTCCCAGGG	RAF1	ENSG00000132155	-0.836213786374241	[318]	[156,99,57]	-7	hSpCas9	negative selection	2136337
12604220	12604243	3	+	26627737	HCT116	viability after 15 days	GGAACCTTCAGATGAGGGACTGG	RAF1	ENSG00000132155	-1.079224180573912	[279]	[24,29,165]	-8	hSpCas9	negative selection	2136340
12608851	12608874	3	+	26627737	HCT116	viability after 15 days	GACATCGAAATCCATTGAGCAGG	RAF1	ENSG00000132155	0.2639428385824305	[233]	[215,134,139]	2	hSpCas9	negative selection	2136341
12618599	12618622	3	-	26627737	HCT116	viability after 15 days	AGCAGTTTGGCTATCAGCGCCGG	RAF1	ENSG00000132155	-2.9744585138014936	[755]	[51,30,81]	-9	hSpCas9	negative selection	2136343
12590899	12590922	3	-	26627737	HCT116	viability after 18 days	ACCTGGCAATTGTGACCCAGTGG	RAF1	ENSG00000132155	-5.973815437373033	[129]	[0,0,0]	-9	hSpCas9	negative selection	2218645
12600187	12600210	3	-	26627737	HCT116	viability after 18 days	CGTGCCAGCACAAAGAGAGCGGG	RAF1	ENSG00000132155	-2.357074799557771	[515]	[52,38,54]	-9	hSpCas9	negative selection	2218649
12603510	12603533	3	-	26627737	HCT116	viability after 18 days	CAACCTGAGTGCTTCTCCCAGGG	RAF1	ENSG00000132155	-1.213091390356674	[318]	[87,53,57]	-8	hSpCas9	negative selection	2218652
12604220	12604243	3	+	26627737	HCT116	viability after 18 days	GGAACCTTCAGATGAGGGACTGG	RAF1	ENSG00000132155	-1.8084518661451394	[279]	[29,15,72]	-8	hSpCas9	negative selection	2218655
12608851	12608874	3	+	26627737	HCT116	viability after 18 days	GACATCGAAATCCATTGAGCAGG	RAF1	ENSG00000132155	0.26421445064767385	[233]	[118,164,120]	2	hSpCas9	negative selection	2218656
12618599	12618622	3	-	26627737	HCT116	viability after 18 days	AGCAGTTTGGCTATCAGCGCCGG	RAF1	ENSG00000132155	-2.7289727752174917	[755]	[106,19,39]	-9	hSpCas9	negative selection	2218658
12618549	12618572	3	+	24336569	HL60	viability	ATAGTGTTGCTTGTCTTAGAAGG	RAF1	ENSG00000132155	0.9092580857830928	[194]	[774]	7	hSpCas9	negative selection	2288202
12618585	12618608	3	-	24336569	HL60	viability	CAGCGCCGGGCATCAGATGATGG	RAF1	ENSG00000132155	-1.1882593348941073	[924]	[858]	-8	hSpCas9	negative selection	2288203
12618598	12618621	3	-	24336569	HL60	viability	GCAGTTTGGCTATCAGCGCCGGG	RAF1	ENSG00000132155	-0.9060639691204326	[262]	[296]	-7	hSpCas9	negative selection	2288204
12618612	12618635	3	-	24336569	HL60	viability	CCTACAATAGTTCAGCAGTTTGG	RAF1	ENSG00000132155	0.985765951085225	[282]	[1185]	7	hSpCas9	negative selection	2288205
12618626	12618649	3	+	24336569	HL60	viability	TATTGTAGGAGAGATGCAGCTGG	RAF1	ENSG00000132155	-0.518126358234714	[1657]	[2449]	-5	hSpCas9	negative selection	2288206
12618641	12618664	3	+	24336569	HL60	viability	GCAGCTGGAGCCATCAAACACGG	RAF1	ENSG00000132155	-1.4057618019195863	[913]	[729]	-8	hSpCas9	negative selection	2288207
12618651	12618674	3	-	24336569	HL60	viability	TTCAAAGATGCCGTGTTTGATGG	RAF1	ENSG00000132155	-0.2590508037792755	[1061]	[1877]	-2	hSpCas9	negative selection	2288208
12618681	12618704	3	-	24336569	HL60	viability	GCTTGGAAGACGATCAGCAATGG	RAF1	ENSG00000132155	-0.18580076044363186	[730]	[1359]	-2	hSpCas9	negative selection	2288209
12618698	12618721	3	-	24336569	HL60	viability	TGGAGCACATACAGGGAGCTTGG	RAF1	ENSG00000132155	-0.3730756293723131	[723]	[1182]	-3	hSpCas9	negative selection	2288210
12618705	12618728	3	-	24336569	HL60	viability	GCATCAATGGAGCACATACAGGG	RAF1	ENSG00000132155	-0.45981874710853216	[918]	[1413]	-4	hSpCas9	negative selection	2288211
12618549	12618572	3	+	24336569	KBM7	viability	ATAGTGTTGCTTGTCTTAGAAGG	RAF1	ENSG00000132155	1.27266900267239	[216]	[1429]	9	hSpCas9	negative selection	2355379
12618585	12618608	3	-	24336569	KBM7	viability	CAGCGCCGGGCATCAGATGATGG	RAF1	ENSG00000132155	-0.26700695090706145	[584]	[1325]	-2	hSpCas9	negative selection	2355380
12618598	12618621	3	-	24336569	KBM7	viability	GCAGTTTGGCTATCAGCGCCGGG	RAF1	ENSG00000132155	-0.9716273177464316	[370]	[515]	-6	hSpCas9	negative selection	2355381
12618612	12618635	3	-	24336569	KBM7	viability	CCTACAATAGTTCAGCAGTTTGG	RAF1	ENSG00000132155	0.819539902841461	[337]	[1626]	7	hSpCas9	negative selection	2355382
12618626	12618649	3	+	24336569	KBM7	viability	TATTGTAGGAGAGATGCAGCTGG	RAF1	ENSG00000132155	-0.14628446592066835	[1168]	[2880]	-1	hSpCas9	negative selection	2355383
12618641	12618664	3	+	24336569	KBM7	viability	GCAGCTGGAGCCATCAAACACGG	RAF1	ENSG00000132155	-0.3022278109762625	[749]	[1658]	-3	hSpCas9	negative selection	2355384
12618651	12618674	3	-	24336569	KBM7	viability	TTCAAAGATGCCGTGTTTGATGG	RAF1	ENSG00000132155	0.7741507999442598	[777]	[3628]	7	hSpCas9	negative selection	2355385
12618681	12618704	3	-	24336569	KBM7	viability	GCTTGGAAGACGATCAGCAATGG	RAF1	ENSG00000132155	-0.8122583984403371	[928]	[1442]	-6	hSpCas9	negative selection	2355386
12618698	12618721	3	-	24336569	KBM7	viability	TGGAGCACATACAGGGAGCTTGG	RAF1	ENSG00000132155	0.04382086318077827	[636]	[1790]	0	hSpCas9	negative selection	2355387
12618705	12618728	3	-	24336569	KBM7	viability	GCATCAATGGAGCACATACAGGG	RAF1	ENSG00000132155	-0.3601163552985431	[519]	[1104]	-3	hSpCas9	negative selection	2355388
12620190	12620213	3	+	25494202	A375	resistance to PLX-4720 (puromycin)	GGAGTGTAGTGGCGCGATCTTGG	RAF1	ENSG00000132155	3.1722237697093507	[103,9]	[210,6]	8	dCas9-VP64	positive selection	2392296
12641952	12641975	3	-	25494202	A375	resistance to PLX-4720 (puromycin)	AGGGTTTCACCATGTTGGCCCAG	RAF1	ENSG00000132155	0.051094447397205506	[27,110]	[6,24]	0	dCas9-VP64	positive selection	2397817
12633889	12633912	3	+	25494202	A375	resistance to PLX-4720 (puromycin)	TGTGCCATTGCACTCCAGCCAGG	RAF1	ENSG00000132155	-1.8772669929253083	[207,39]	[9,2]	-9	dCas9-VP64	positive selection	2411656
12642391	12642414	3	+	25494202	A375	resistance to PLX-4720 (puromycin)	CCCAGCTAGTCGGGAGGCTGAGG	RAF1	ENSG00000132155	2.1714672198883793	[6,0]	[5,0]	7	dCas9-VP64	positive selection	2426448
12606578	12606601	3	+	25494202	A375	resistance to PLX-4720 (puromycin)	TTGCCCAGGCTGGAGTGCAGAGG	RAF1	ENSG00000132155	0.9977856233970179	[9,4]	[4,0]	4	dCas9-VP64	positive selection	2435961
12641342	12641365	3	+	25494202	A375	resistance to PLX-4720 (puromycin)	CACATGTACTCTAGAACTTAAAG	RAF1	ENSG00000132155	2.392838046057667	[630,78]	[768,13]	7	dCas9-VP64	positive selection	2447970
12652685	12652708	3	+	25494202	A375	resistance to PLX-4720 (puromycin)	CATCTGTAATCCCAGCACTTGGG	RAF1	ENSG00000132155	0.936948372456865	[294,1308]	[29,678]	4	dCas9-VP64	positive selection	2456761
12654019	12654042	3	+	25494202	A375	resistance to PLX-4720 (puromycin)	TCTTGTTCTGTTGCCCAGGCTAG	RAF1	ENSG00000132155	-0.6863317618464422	[59,137]	[14,10]	-3	dCas9-VP64	positive selection	2464085
12600837	12600860	3	+	25494202	A375	resistance to PLX-4720 (puromycin)	CAGGCGTGAGCCACCGTGCCAAG	RAF1	ENSG00000132155	0.40998119487686246	[103,58]	[28,16]	1	dCas9-VP64	positive selection	2466068
12634407	12634430	3	+	25494202	A375	resistance to PLX-4720 (puromycin)	TCCCAAAATGCTGGGATTACGGG	RAF1	ENSG00000132155	0.20161513672590614	[46,60]	[10,15]	1	dCas9-VP64	positive selection	2475366
12620190	12620213	3	+	25494202	A375	resistance to PLX-4720 (zeocin)	GGAGTGTAGTGGCGCGATCTTGG	RAF1	ENSG00000132155	0.8627698723325049	[50,145]	[36,76]	6	dCas9-VP64	positive selection	2487551
12641952	12641975	3	-	25494202	A375	resistance to PLX-4720 (zeocin)	AGGGTTTCACCATGTTGGCCCAG	RAF1	ENSG00000132155	-0.16706931973118405	[70,280]	[30,67]	-2	dCas9-VP64	positive selection	2493072
12633889	12633912	3	+	25494202	A375	resistance to PLX-4720 (zeocin)	TGTGCCATTGCACTCCAGCCAGG	RAF1	ENSG00000132155	1.3157553862059514	[45,21]	[16,37]	7	dCas9-VP64	positive selection	2506911
12642391	12642414	3	+	25494202	A375	resistance to PLX-4720 (zeocin)	CCCAGCTAGTCGGGAGGCTGAGG	RAF1	ENSG00000132155	0.040699992828052034	[136,33]	[49,8]	0	dCas9-VP64	positive selection	2521703
12606578	12606601	3	+	25494202	A375	resistance to PLX-4720 (zeocin)	TTGCCCAGGCTGGAGTGCAGAGG	RAF1	ENSG00000132155	-0.1814090993543942	[50,40]	[18,6]	-2	dCas9-VP64	positive selection	2531216
12641342	12641365	3	+	25494202	A375	resistance to PLX-4720 (zeocin)	CACATGTACTCTAGAACTTAAAG	RAF1	ENSG00000132155	2.165488173425687	[88,62]	[27,190]	8	dCas9-VP64	positive selection	2543225
12652685	12652708	3	+	25494202	A375	resistance to PLX-4720 (zeocin)	CATCTGTAATCCCAGCACTTGGG	RAF1	ENSG00000132155	-0.19682723409902197	[171,197]	[36,65]	-2	dCas9-VP64	positive selection	2552016
12654019	12654042	3	+	25494202	A375	resistance to PLX-4720 (zeocin)	TCTTGTTCTGTTGCCCAGGCTAG	RAF1	ENSG00000132155	-0.6931781766025115	[37,108]	[16,10]	-6	dCas9-VP64	positive selection	2559340
12600837	12600860	3	+	25494202	A375	resistance to PLX-4720 (zeocin)	CAGGCGTGAGCCACCGTGCCAAG	RAF1	ENSG00000132155	0.6377058725861018	[58,96]	[43,34]	5	dCas9-VP64	positive selection	2561323
12634407	12634430	3	+	25494202	A375	resistance to PLX-4720 (zeocin)	TCCCAAAATGCTGGGATTACGGG	RAF1	ENSG00000132155	-0.42275240861415275	[53,301]	[32,50]	-4	dCas9-VP64	positive selection	2570621
12591692	12591715	3	-	27013184	SW480	treatment with recombinant TRAIL	TTCTGCGGTGAGTAGAAAGCTGG	RAF1	ENSG00000132155	-2.391919958506846	[418,431]	[36,31]	-8	hSpCas9	positive selection	2959830
12591718	12591741	3	-	27013184	SW480	treatment with recombinant TRAIL	CCAGGCCTTCAGGAATGAGGTGG	RAF1	ENSG00000132155	3.645504421071793	[3,28]	[111,41]	9	hSpCas9	positive selection	2959831
12591728	12591751	3	-	27013184	SW480	treatment with recombinant TRAIL	CAGAGCAATTCCAGGCCTTCAGG	RAF1	ENSG00000132155	-0.34643294247708156	[545,572]	[179,202]	-1	hSpCas9	positive selection	2959832
12591766	12591789	3	-	27013184	SW480	treatment with recombinant TRAIL	TGTTGCAGTAAAGATCCTAAAGG	RAF1	ENSG00000132155	-0.2883656757961499	[16,27]	[1,15]	-1	hSpCas9	positive selection	2959833
12591792	12591815	3	-	27013184	SW480	treatment with recombinant TRAIL	TGACTGCCAACTAATTTTGCAGG	RAF1	ENSG00000132155	-1.9825357106779085	[232,352]	[4,68]	-7	hSpCas9	positive selection	2959834
12608784	12608807	3	+	27013184	SW480	treatment with recombinant TRAIL	CTCCAGTCCACACACATAGTAGG	RAF1	ENSG00000132155	-1.054554173962576	[157,212]	[49,20]	-5	hSpCas9	positive selection	2959835
12608851	12608874	3	+	27013184	SW480	treatment with recombinant TRAIL	GACATCGAAATCCATTGAGCAGG	RAF1	ENSG00000132155	2.05594343947013	[171,124]	[308,214]	8	hSpCas9	positive selection	2959836
12609244	12609267	3	+	27013184	SW480	treatment with recombinant TRAIL	TTGTGAGGGGAACATGATCCAGG	RAF1	ENSG00000132155	1.4384466323830158	[12,28]	[38,1]	6	hSpCas9	positive selection	2959837
12611971	12611994	3	+	27013184	SW480	treatment with recombinant TRAIL	CTGAACACTGCACAGCACTCTGG	RAF1	ENSG00000132155	2.796781652076678	[186,31]	[147,634]	9	hSpCas9	positive selection	2959838
12611978	12612001	3	+	27013184	SW480	treatment with recombinant TRAIL	CTGCACAGCACTCTGGTTGCAGG	RAF1	ENSG00000132155	1.9558958534738133	[210,278]	[251,622]	8	hSpCas9	positive selection	2959839
12618651	12618674	3	-	27013184	SW480	treatment with recombinant TRAIL	TTCAAAGATGCCGTGTTTGATGG	RAF1	ENSG00000132155	-1.0063138737053858	[379,380]	[70,96]	-4	hSpCas9	positive selection	2959840
12618675	12618698	3	-	27013184	SW480	treatment with recombinant TRAIL	AAGACGATCAGCAATGGTTTTGG	RAF1	ENSG00000132155	3.8362078750252713	[55,84]	[400,462]	9	hSpCas9	positive selection	2959841
12618698	12618721	3	-	27013184	SW480	treatment with recombinant TRAIL	TGGAGCACATACAGGGAGCTTGG	RAF1	ENSG00000132155	1.0198526161960317	[182,173]	[125,199]	5	hSpCas9	positive selection	2959842
12618705	12618728	3	-	27013184	SW480	treatment with recombinant TRAIL	GCATCAATGGAGCACATACAGGG	RAF1	ENSG00000132155	2.7693696107678734	[226,458]	[1294,528]	9	hSpCas9	positive selection	2959843
12618706	12618729	3	-	27013184	SW480	treatment with recombinant TRAIL	TGCATCAATGGAGCACATACAGG	RAF1	ENSG00000132155	-0.8678337249436765	[93,104]	[22,23]	-4	hSpCas9	positive selection	2959844
12618718	12618741	3	-	27013184	SW480	treatment with recombinant TRAIL	AATTGTTTAAGCTGCATCAATGG	RAF1	ENSG00000132155	0.23408473878434077	[393,535]	[290,149]	1	hSpCas9	positive selection	2959845
12591718	12591741	3	+	27013184	SW480	treatment with recombinant TRAIL	CCACCTCATTCCTGAAGGCCTGG	RAF1	ENSG00000132155	0.4445389702341427	[618,613]	[310,434]	2	hSpCas9	positive selection	2959846
12591729	12591752	3	+	27013184	SW480	treatment with recombinant TRAIL	CTGAAGGCCTGGAATTGCTCTGG	RAF1	ENSG00000132155	3.6684569516907537	[706,721]	[2846,5438]	9	hSpCas9	positive selection	2959847
12591730	12591753	3	+	27013184	SW480	treatment with recombinant TRAIL	TGAAGGCCTGGAATTGCTCTGGG	RAF1	ENSG00000132155	0.9101903794767155	[98,116]	[36,157]	4	hSpCas9	positive selection	2959848
12591731	12591754	3	+	27013184	SW480	treatment with recombinant TRAIL	GAAGGCCTGGAATTGCTCTGGGG	RAF1	ENSG00000132155	1.1259928824394678	[259,260]	[163,360]	5	hSpCas9	positive selection	2959849
12591751	12591774	3	+	27013184	SW480	treatment with recombinant TRAIL	GGGTTGGGTCGACAACCTTTAGG	RAF1	ENSG00000132155	0.4254517861002175	[146,212]	[114,84]	2	hSpCas9	positive selection	2959850
12591786	12591809	3	+	27013184	SW480	treatment with recombinant TRAIL	ACATCTCCTGCAAAATTAGTTGG	RAF1	ENSG00000132155	0.5135781927363965	[531,532]	[216,485]	2	hSpCas9	positive selection	2959851
12608760	12608783	3	-	27013184	SW480	treatment with recombinant TRAIL	AACATCAGACAACTCTTGTAAGG	RAF1	ENSG00000132155	2.350234940147917	[175,251]	[389,567]	8	hSpCas9	positive selection	2959852
12608786	12608809	3	-	27013184	SW480	treatment with recombinant TRAIL	TACCTACTATGTGTGTGGACTGG	RAF1	ENSG00000132155	0.41421111638770325	[339,360]	[193,210]	2	hSpCas9	positive selection	2959853
12608841	12608864	3	-	27013184	SW480	treatment with recombinant TRAIL	GGATTTCGATGTCAGACTTGTGG	RAF1	ENSG00000132155	1.8480856765346854	[150,264]	[292,346]	7	hSpCas9	positive selection	2959854
12608862	12608885	3	-	27013184	SW480	treatment with recombinant TRAIL	TGTCAGAAATTCCTGCTCAATGG	RAF1	ENSG00000132155	0.09495955764509745	[505,596]	[241,266]	0	hSpCas9	positive selection	2959855
12611949	12611972	3	-	27013184	SW480	treatment with recombinant TRAIL	GACTTCTCCACGAACACAAAGGG	RAF1	ENSG00000132155	0.7036731170007575	[196,245]	[64,280]	3	hSpCas9	positive selection	2959856
12611950	12611973	3	-	27013184	SW480	treatment with recombinant TRAIL	AGACTTCTCCACGAACACAAAGG	RAF1	ENSG00000132155	2.349937892670265	[239,259]	[559,530]	8	hSpCas9	positive selection	2959857
12612001	12612024	3	-	27013184	SW480	treatment with recombinant TRAIL	ATGAAAGCACTCAAGGTGAGGGG	RAF1	ENSG00000132155	1.7465859588585178	[167,133]	[108,379]	7	hSpCas9	positive selection	2959858
12612002	12612025	3	-	27013184	SW480	treatment with recombinant TRAIL	TATGAAAGCACTCAAGGTGAGGG	RAF1	ENSG00000132155	2.0739568518489513	[275,458]	[803,437]	8	hSpCas9	positive selection	2959860
12611949	12611972	3	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GACTTCTCCACGAACACAAAGGG	RAF1	ENSG00000132155	0.05235770992886854	[3,3]	[4,1]	1	hSpCas9	positive selection	3015520
12618705	12618728	3	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCATCAATGGAGCACATACAGGG	RAF1	ENSG00000132155	0.06934445633495828	[4,4]	[4,3]	1	hSpCas9	positive selection	3015521
12618514	12618537	3	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCCGAACAAGCAAAGAACAGTGG	RAF1	ENSG00000132155	0.3094387645849013	[4,4]	[3,6]	6	hSpCas9	positive selection	3015522
12618527	12618550	3	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCTTGTTCGGCAAGAAAACACGG	RAF1	ENSG00000132155	-0.18321966771112908	[2,3]	[3,0]	-3	hSpCas9	positive selection	3015523
12611949	12611972	3	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GACTTCTCCACGAACACAAAGGG	RAF1	ENSG00000132155	0.4711582715849528	[3,3]	[3,3]	7	hSpCas9	positive selection	3083378
12618705	12618728	3	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCATCAATGGAGCACATACAGGG	RAF1	ENSG00000132155	-0.25513753049402965	[4,4]	[3,1]	-4	hSpCas9	positive selection	3083379
12618514	12618537	3	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCCGAACAAGCAAAGAACAGTGG	RAF1	ENSG00000132155	0.26561673176359935	[4,4]	[5,3]	5	hSpCas9	positive selection	3083380
12618527	12618550	3	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCTTGTTCGGCAAGAAAACACGG	RAF1	ENSG00000132155	-0.2608713752738038	[2,2]	[1,1]	-4	hSpCas9	positive selection	3083381
12618585	12618608		-	24336571	A375	resistance to PLX after 7 days	CAGCGCCGGGCATCAGATGATGG	RAF1	ENSG00000132155	-0.15474767549722812	[7,6]	[7,5]	-5	hSpCas9	positive selection	3139615
12618681	12618704		-	24336571	A375	resistance to PLX after 7 days	GCTTGGAAGACGATCAGCAATGG	RAF1	ENSG00000132155	-0.1091587206043434	[5,5]	[5,4]	-3	hSpCas9	positive selection	3139616
12609314	12609337		-	24336571	A375	resistance to PLX after 7 days	GTAAAAAAGCACGCTTAGATTGG	RAF1	ENSG00000132155	0.3400119895865208	[3,4]	[5,5]	8	hSpCas9	positive selection	3139618
12618706	12618729		-	24336571	A375	resistance to PLX after 7 days	TGCATCAATGGAGCACATACAGG	RAF1	ENSG00000132155	-0.295685810293365	[10,8]	[7,8]	-8	hSpCas9	positive selection	3139619
12618585	12618608		-	24336571	A375	resistance to PLX after 14 days	CAGCGCCGGGCATCAGATGATGG	RAF1	ENSG00000132155	-0.2569037191121393	[7,7]	[2,2]	-3	hSpCas9	positive selection	3197408
12618681	12618704		-	24336571	A375	resistance to PLX after 14 days	GCTTGGAAGACGATCAGCAATGG	RAF1	ENSG00000132155	0.38863388143703004	[4,3]	[1,2]	4	hSpCas9	positive selection	3197409
12609314	12609337		-	24336571	A375	resistance to PLX after 14 days	GTAAAAAAGCACGCTTAGATTGG	RAF1	ENSG00000132155	1.7225231691198393	[3,3]	[8,3]	9	hSpCas9	positive selection	3197411
12618706	12618729		-	24336571	A375	resistance to PLX after 14 days	TGCATCAATGGAGCACATACAGG	RAF1	ENSG00000132155	-0.5091342993018246	[8,9]	[2,1]	-6	hSpCas9	positive selection	3197412
12618585	12618608		-	24336571	A375	viability after 7 days	CAGCGCCGGGCATCAGATGATGG	RAF1	ENSG00000132155	0.14881171560302198	[6]	[7,6]	2	hSpCas9	negative selection	3255201
12618681	12618704		-	24336571	A375	viability after 7 days	GCTTGGAAGACGATCAGCAATGG	RAF1	ENSG00000132155	0.3737004184338224	[4]	[5,5]	5	hSpCas9	negative selection	3255202
12609314	12609337		-	24336571	A375	viability after 7 days	GTAAAAAAGCACGCTTAGATTGG	RAF1	ENSG00000132155	-0.953868657933294	[9]	[3,4]	-8	hSpCas9	negative selection	3255204
12618706	12618729		-	24336571	A375	viability after 7 days	TGCATCAATGGAGCACATACAGG	RAF1	ENSG00000132155	-0.7183916155106258	[17]	[10,8]	-8	hSpCas9	negative selection	3255205
12618585	12618608		-	24336571	A375	viability after 14 days	CAGCGCCGGGCATCAGATGATGG	RAF1	ENSG00000132155	0.20881259605357416	[6]	[7,7]	2	hSpCas9	negative selection	3312994
12618681	12618704		-	24336571	A375	viability after 14 days	GCTTGGAAGACGATCAGCAATGG	RAF1	ENSG00000132155	0.014386515818007428	[4]	[4,3]	0	hSpCas9	negative selection	3312995
12609314	12609337		-	24336571	A375	viability after 14 days	GTAAAAAAGCACGCTTAGATTGG	RAF1	ENSG00000132155	-1.105638363367155	[9]	[3,3]	-8	hSpCas9	negative selection	3312997
12618706	12618729		-	24336571	A375	viability after 14 days	TGCATCAATGGAGCACATACAGG	RAF1	ENSG00000132155	-0.8318004064605924	[17]	[8,9]	-8	hSpCas9	negative selection	3312998
12609288	12609311	3	-	27383988	293T	resistance to West Nile virus (flavivirus)	ACTGATGCTGCGTCTTTGATTGG	RAF1	ENSG00000132155	0.9353981165584726	[319,319]	[3,3]	4	hSpCas9	positive selection	3388876
12604174	12604197	3	-	27383988	293T	resistance to West Nile virus (flavivirus)	ATCCACACCTAATGTCCACATGG	RAF1	ENSG00000132155	-0.5692222758450799	[226,226]	[0,0]	-4	hSpCas9	positive selection	3388877
12604167	12604190	3	+	27383988	293T	resistance to West Nile virus (flavivirus)	GTGCTGACCATGTGGACATTAGG	RAF1	ENSG00000132155	-0.38652997832888963	[199,199]	[0,0]	-2	hSpCas9	positive selection	3388878
12611949	12611972	3	-	26780180	HT29	viability (Avana library 4 designs)	GACTTCTCCACGAACACAAAGGG	RAF1	ENSG00000132155	-0.209725499718835	[]	[]	-3	hSpCas9	negative selection	3453780
12618705	12618728	3	-	26780180	HT29	viability (Avana library 4 designs)	GCATCAATGGAGCACATACAGGG	RAF1	ENSG00000132155	0.283567322435234	[]	[]	1	hSpCas9	negative selection	3453781
12618514	12618537	3	-	26780180	HT29	viability (Avana library 4 designs)	GCCGAACAAGCAAAGAACAGTGG	RAF1	ENSG00000132155	0.391796589990741	[]	[]	1	hSpCas9	negative selection	3453782
12618526	12618549	3	+	26780180	HT29	viability (Avana library 4 designs)	GCTTGTTCGGCAAGAAAACACGG	RAF1	ENSG00000132155	1.62764773231321	[]	[]	6	hSpCas9	negative selection	3453783
12618705	12618728	3	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCATCAATGGAGCACATACAGGG	RAF1	ENSG00000132155	1.99176277565193	[]	[]	3	hSpCas9	negative selection	3550809
12618526	12618549	3	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCTTGTTCGGCAAGAAAACACGG	RAF1	ENSG00000132155	-12.7717761144865	[]	[]	-8	hSpCas9	negative selection	3550810
12611949	12611972	3	-	26780180	A375	viability (Avana lentiCRISPRv2)	GACTTCTCCACGAACACAAAGGG	RAF1	ENSG00000132155	-2.34965448725751	[]	[]	-3	hSpCas9	negative selection	3550811
12618514	12618537	3	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCCGAACAAGCAAAGAACAGTGG	RAF1	ENSG00000132155	-2.56889451348207	[]	[]	-3	hSpCas9	negative selection	3550812
12604137	12604160	3	+	26780180	A375	viability (Avana lentiCRISPRv2)	TCAATCATCCTGCTGTCCACAGG	RAF1	ENSG00000132155	-4.5895949181445	[]	[]	-5	hSpCas9	negative selection	3550813
12618681	12618704	3	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCTTGGAAGACGATCAGCAATGG	RAF1	ENSG00000132155	-3.76545949717058	[]	[]	-4	hSpCas9	negative selection	3550814
12618705	12618728	3	-	26780180	A375	viability (Avana lentiGuide)	GCATCAATGGAGCACATACAGGG	RAF1	ENSG00000132155	-2.13890113350587	[]	[]	-4	hSpCas9	negative selection	3659468
12618526	12618549	3	+	26780180	A375	viability (Avana lentiGuide)	GCTTGTTCGGCAAGAAAACACGG	RAF1	ENSG00000132155	-4.48151068340754	[]	[]	-7	hSpCas9	negative selection	3659469
12611949	12611972	3	-	26780180	A375	viability (Avana lentiGuide)	GACTTCTCCACGAACACAAAGGG	RAF1	ENSG00000132155	-3.43674439557406	[]	[]	-6	hSpCas9	negative selection	3659470
12618514	12618537	3	-	26780180	A375	viability (Avana lentiGuide)	GCCGAACAAGCAAAGAACAGTGG	RAF1	ENSG00000132155	-2.30786521130423	[]	[]	-4	hSpCas9	negative selection	3659471
12604137	12604160	3	+	26780180	A375	viability (Avana lentiGuide)	TCAATCATCCTGCTGTCCACAGG	RAF1	ENSG00000132155	1.68406899598135	[]	[]	2	hSpCas9	negative selection	3659472
12618681	12618704	3	-	26780180	A375	viability (Avana lentiGuide)	GCTTGGAAGACGATCAGCAATGG	RAF1	ENSG00000132155	8.53232791425125	[]	[]	6	hSpCas9	negative selection	3659473
12618705	12618728	3	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCATCAATGGAGCACATACAGGG	RAF1	ENSG00000132155	0.1659461606646381	[5]	[7,5]	4	hSpCas9	positive selection	3768075
12618526	12618549	3	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCTTGTTCGGCAAGAAAACACGG	RAF1	ENSG00000132155	-2.1046640298012935	[4]	[0,0]	-9	hSpCas9	positive selection	3768076
12611949	12611972	3	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GACTTCTCCACGAACACAAAGGG	RAF1	ENSG00000132155	-0.2682664411884686	[4]	[4,2]	-4	hSpCas9	positive selection	3768077
12618514	12618537	3	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCCGAACAAGCAAAGAACAGTGG	RAF1	ENSG00000132155	-0.10265054960303077	[5]	[4,4]	-2	hSpCas9	positive selection	3768078
12604137	12604160	3	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TCAATCATCCTGCTGTCCACAGG	RAF1	ENSG00000132155	-0.2491965538012841	[5]	[4,4]	-4	hSpCas9	positive selection	3768079
12618681	12618704	3	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCTTGGAAGACGATCAGCAATGG	RAF1	ENSG00000132155	-0.3033293483532122	[4]	[2,4]	-4	hSpCas9	positive selection	3768080
12618705	12618728	3	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCATCAATGGAGCACATACAGGG	RAF1	ENSG00000132155	0.21905719339263857	[6]	[6,5]	5	hSpCas9	positive selection	3876682
12618526	12618549	3	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCTTGTTCGGCAAGAAAACACGG	RAF1	ENSG00000132155	-0.08716973955708104	[5]	[4,2]	-1	hSpCas9	positive selection	3876683
12611949	12611972	3	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GACTTCTCCACGAACACAAAGGG	RAF1	ENSG00000132155	-0.025343486673924293	[5]	[6,2]	0	hSpCas9	positive selection	3876684
12618514	12618537	3	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCCGAACAAGCAAAGAACAGTGG	RAF1	ENSG00000132155	0.15432456443798936	[6]	[5,6]	3	hSpCas9	positive selection	3876685
12604137	12604160	3	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TCAATCATCCTGCTGTCCACAGG	RAF1	ENSG00000132155	0.020123836762091202	[6]	[4,5]	0	hSpCas9	positive selection	3876686
12618681	12618704	3	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCTTGGAAGACGATCAGCAATGG	RAF1	ENSG00000132155	-0.10039970311774568	[4]	[3,3]	-1	hSpCas9	positive selection	3876687
12609288	12609311	3	-	26780180	A375	viability	ACTGATGCTGCGTCTTTGATTGG	RAF1	ENSG00000132155	0.773089932847207	[]	[]	3	hSpCas9	negative selection	3987095
12604174	12604197	3	-	26780180	A375	viability	ATCCACACCTAATGTCCACATGG	RAF1	ENSG00000132155	1.26843354125573	[]	[]	7	hSpCas9	negative selection	3987096
12618585	12618608	3	-	26780180	A375	viability	CAGCGCCGGGCATCAGATGATGG	RAF1	ENSG00000132155	1.07807598318988	[]	[]	5	hSpCas9	negative selection	3987097
12618681	12618704	3	-	26780180	A375	viability	GCTTGGAAGACGATCAGCAATGG	RAF1	ENSG00000132155	0.775279712003811	[]	[]	3	hSpCas9	negative selection	3987098
12609314	12609337	3	-	26780180	A375	viability	GTAAAAAAGCACGCTTAGATTGG	RAF1	ENSG00000132155	0.86070393978924	[]	[]	3	hSpCas9	negative selection	3987099
12604167	12604190	3	+	26780180	A375	viability	GTGCTGACCATGTGGACATTAGG	RAF1	ENSG00000132155	0.424110676914585	[]	[]	1	hSpCas9	negative selection	3987100
12609288	12609311	3	-	26780180	HT29	viability (GeCKOv2 library)	ACTGATGCTGCGTCTTTGATTGG	RAF1	ENSG00000132155	0.692148388185556	[]	[]	2	hSpCas9	negative selection	4095061
12604174	12604197	3	-	26780180	HT29	viability (GeCKOv2 library)	ATCCACACCTAATGTCCACATGG	RAF1	ENSG00000132155	0.762945103953763	[]	[]	3	hSpCas9	negative selection	4095062
12618585	12618608	3	-	26780180	HT29	viability (GeCKOv2 library)	CAGCGCCGGGCATCAGATGATGG	RAF1	ENSG00000132155	1.99312814156193	[]	[]	9	hSpCas9	negative selection	4095063
12618681	12618704	3	-	26780180	HT29	viability (GeCKOv2 library)	GCTTGGAAGACGATCAGCAATGG	RAF1	ENSG00000132155	0.949608988973309	[]	[]	4	hSpCas9	negative selection	4095064
12609314	12609337	3	-	26780180	HT29	viability (GeCKOv2 library)	GTAAAAAAGCACGCTTAGATTGG	RAF1	ENSG00000132155	0.50731699943969	[]	[]	1	hSpCas9	negative selection	4095065
12604167	12604190	3	+	26780180	HT29	viability (GeCKOv2 library)	GTGCTGACCATGTGGACATTAGG	RAF1	ENSG00000132155	1.00708239098947	[]	[]	4	hSpCas9	negative selection	4095066
12618585	12618608	3	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CAGCGCCGGGCATCAGATGATGG	RAF1	ENSG00000132155	-0.3423301928903265	[2]	[0,1]	-7	hSpCas9	positive selection	4164968
12618681	12618704	3	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GCTTGGAAGACGATCAGCAATGG	RAF1	ENSG00000132155	0.1744966646271222	[1]	[0,1]	4	hSpCas9	positive selection	4164969
12609314	12609337	3	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GTAAAAAAGCACGCTTAGATTGG	RAF1	ENSG00000132155	0.27741439171298243	[2]	[1,2]	7	hSpCas9	positive selection	4164971
12618706	12618729	3	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TGCATCAATGGAGCACATACAGG	RAF1	ENSG00000132155	-0.2257524712830684	[2]	[1,1]	-5	hSpCas9	positive selection	4164972
12618585	12618608	3	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CAGCGCCGGGCATCAGATGATGG	RAF1	ENSG00000132155	-0.15976610192425877	[2]	[0,0,0,0]	-2	hSpCas9	positive selection	4228990
12618681	12618704	3	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GCTTGGAAGACGATCAGCAATGG	RAF1	ENSG00000132155	0.23892083007132686	[3]	[2,0,3,0]	2	hSpCas9	positive selection	4228991
12609314	12609337	3	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GTAAAAAAGCACGCTTAGATTGG	RAF1	ENSG00000132155	-0.9052526346884271	[3]	[0,0,0,0]	-9	hSpCas9	positive selection	4228993
12618706	12618729	3	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TGCATCAATGGAGCACATACAGG	RAF1	ENSG00000132155	0.09827147694292071	[3]	[4,2,0,0]	0	hSpCas9	positive selection	4228994
12609314	12609337	3	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GTAAAAAAGCACGCTTAGATTGG	RAF1	ENSG00000132155	0.1988421925448794	[2]	[1,1]	4	hSpCas9	positive selection	4293760
12618585	12618608	3	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CAGCGCCGGGCATCAGATGATGG	RAF1	ENSG00000132155	-0.34210917986607164	[2]	[0,1]	-6	hSpCas9	positive selection	4293761
12618681	12618704	3	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GCTTGGAAGACGATCAGCAATGG	RAF1	ENSG00000132155	-0.03714001992021532	[3]	[2,2]	0	hSpCas9	positive selection	4293762
12609288	12609311	3	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ACTGATGCTGCGTCTTTGATTGG	RAF1	ENSG00000132155	-0.11385834799276165	[3]	[3,1]	-2	hSpCas9	positive selection	4358018
12604174	12604197	3	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ATCCACACCTAATGTCCACATGG	RAF1	ENSG00000132155	0.15603434889555834	[3]	[3,3]	3	hSpCas9	positive selection	4358019
12604167	12604190	3	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GTGCTGACCATGTGGACATTAGG	RAF1	ENSG00000132155	0.13024410928186314	[2]	[3,1]	2	hSpCas9	positive selection	4358020
12606195	12606217	3	+	27760321	OCIAML3	viability	AATTACCTAACAGGCATCCTGG	RAF1	ENSG00000132155	-1.6238424844071664	[419,309]	[63,127]	-8	hSpCas9	negative selection	4432956
12606267	12606289	3	-	27760321	OCIAML3	viability	ATTCCACTATTGGTGATAGTGG	RAF1	ENSG00000132155	-0.4535914946734465	[81,82]	[12,91]	-4	hSpCas9	negative selection	4432957
12612046	12612068	3	-	27760321	OCIAML3	viability	TGTAGGTCAATGTGCGAAATGG	RAF1	ENSG00000132155	-1.4722611268295829	[256,229]	[58,80]	-8	hSpCas9	negative selection	4432958
12618585	12618607	3	-	27760321	OCIAML3	viability	AGCGCCGGGCATCAGATGATGG	RAF1	ENSG00000132155	-0.4552000403085356	[667,531]	[311,376]	-4	hSpCas9	negative selection	4432959
12600387	12600409	3	-	27760321	OCIAML3	viability	TTCGAAGTCACAGCGAATCAGG	RAF1	ENSG00000132155	-2.1061366589149197	[363,288]	[51,67]	-9	hSpCas9	negative selection	4432960
12606195	12606217	3	+	27760321	OCIAML2	viability	AATTACCTAACAGGCATCCTGG	RAF1	ENSG00000132155	-1.2038105342048906	[419,309]	[123,130]	-8	hSpCas9	negative selection	4516419
12606267	12606289	3	-	27760321	OCIAML2	viability	ATTCCACTATTGGTGATAGTGG	RAF1	ENSG00000132155	-0.5986117254445564	[81,82]	[29,62]	-6	hSpCas9	negative selection	4516420
12612046	12612068	3	-	27760321	OCIAML2	viability	TGTAGGTCAATGTGCGAAATGG	RAF1	ENSG00000132155	0.47002913548202907	[256,229]	[240,313]	6	hSpCas9	negative selection	4516421
12618585	12618607	3	-	27760321	OCIAML2	viability	AGCGCCGGGCATCAGATGATGG	RAF1	ENSG00000132155	0.4011210917728825	[667,531]	[580,710]	5	hSpCas9	negative selection	4516422
12600387	12600409	3	-	27760321	OCIAML2	viability	TTCGAAGTCACAGCGAATCAGG	RAF1	ENSG00000132155	-1.7066527449950248	[363,288]	[101,51]	-9	hSpCas9	negative selection	4516423
12606195	12606217	3	+	27760321	MV411	viability	AATTACCTAACAGGCATCCTGG	RAF1	ENSG00000132155	-0.05448873217011602	[419,309]	[23,538]	0	hSpCas9	negative selection	4599882
12606267	12606289	3	-	27760321	MV411	viability	ATTCCACTATTGGTGATAGTGG	RAF1	ENSG00000132155	1.944092106229349	[81,82]	[67,423]	9	hSpCas9	negative selection	4599883
12612046	12612068	3	-	27760321	MV411	viability	TGTAGGTCAATGTGCGAAATGG	RAF1	ENSG00000132155	-0.4339276427898652	[256,229]	[113,125]	-3	hSpCas9	negative selection	4599884
12618585	12618607	3	-	27760321	MV411	viability	AGCGCCGGGCATCAGATGATGG	RAF1	ENSG00000132155	-0.012541599095923617	[667,531]	[89,840]	0	hSpCas9	negative selection	4599885
12600387	12600409	3	-	27760321	MV411	viability	TTCGAAGTCACAGCGAATCAGG	RAF1	ENSG00000132155	-2.87444006415157	[363,288]	[29,27]	-9	hSpCas9	negative selection	4599886
12606195	12606217	3	+	27760321	HL60	viability	AATTACCTAACAGGCATCCTGG	RAF1	ENSG00000132155	-0.4707927612671782	[419,309]	[119,311]	-5	hSpCas9	negative selection	4683345
12606267	12606289	3	-	27760321	HL60	viability	ATTCCACTATTGGTGATAGTGG	RAF1	ENSG00000132155	-1.531677246184148	[81,82]	[19,26]	-8	hSpCas9	negative selection	4683346
12612046	12612068	3	-	27760321	HL60	viability	TGTAGGTCAATGTGCGAAATGG	RAF1	ENSG00000132155	-0.2921681429366695	[256,229]	[136,188]	-3	hSpCas9	negative selection	4683347
12618585	12618607	3	-	27760321	HL60	viability	AGCGCCGGGCATCAGATGATGG	RAF1	ENSG00000132155	-1.4931487050939931	[667,531]	[141,205]	-8	hSpCas9	negative selection	4683348
12600387	12600409	3	-	27760321	HL60	viability	TTCGAAGTCACAGCGAATCAGG	RAF1	ENSG00000132155	-0.6645124145085035	[363,288]	[174,158]	-6	hSpCas9	negative selection	4683349
12606195	12606217	3	+	27760321	HT1080	viability	AATTACCTAACAGGCATCCTGG	RAF1	ENSG00000132155	-2.402603286920438	[309,241]	[26,13]	-7	hSpCas9	negative selection	4766808
12606267	12606289	3	-	27760321	HT1080	viability	ATTCCACTATTGGTGATAGTGG	RAF1	ENSG00000132155	-4.27535864930204	[82,64]	[1,0]	-8	hSpCas9	negative selection	4766809
12612046	12612068	3	-	27760321	HT1080	viability	TGTAGGTCAATGTGCGAAATGG	RAF1	ENSG00000132155	-2.249150554301532	[229,179]	[20,12]	-6	hSpCas9	negative selection	4766810
12618585	12618607	3	-	27760321	HT1080	viability	AGCGCCGGGCATCAGATGATGG	RAF1	ENSG00000132155	-7.55935911815726	[531,414]	[0,0]	-9	hSpCas9	negative selection	4766811
12600387	12600409	3	-	27760321	HT1080	viability	TTCGAAGTCACAGCGAATCAGG	RAF1	ENSG00000132155	-3.5254584700698466	[288,225]	[6,10]	-7	hSpCas9	negative selection	4766812
12606195	12606217	3	+	27760321	HT29	viability after 7 days	AATTACCTAACAGGCATCCTGG	RAF1	ENSG00000132155	0.046118184535447915	[309,241]	[418,379,308]	0	hSpCas9	negative selection	4850271
12606267	12606289	3	-	27760321	HT29	viability after 7 days	ATTCCACTATTGGTGATAGTGG	RAF1	ENSG00000132155	0.10056568948772115	[82,64]	[96,66,139]	1	hSpCas9	negative selection	4850272
12612046	12612068	3	-	27760321	HT29	viability after 7 days	TGTAGGTCAATGTGCGAAATGG	RAF1	ENSG00000132155	0.2288873233837625	[229,179]	[263,379,276]	3	hSpCas9	negative selection	4850273
12618585	12618607	3	-	27760321	HT29	viability after 7 days	AGCGCCGGGCATCAGATGATGG	RAF1	ENSG00000132155	0.5148646644896752	[531,414]	[837,1158,614]	7	hSpCas9	negative selection	4850274
12600387	12600409	3	-	27760321	HT29	viability after 7 days	TTCGAAGTCACAGCGAATCAGG	RAF1	ENSG00000132155	-0.3009371240219224	[288,225]	[197,238,355]	-4	hSpCas9	negative selection	4850275
12606195	12606217	3	+	27760321	HT29	viability after 25 days	AATTACCTAACAGGCATCCTGG	RAF1	ENSG00000132155	-0.44209527757158357	[309,241]	[326,192,162]	-4	hSpCas9	negative selection	4933734
12606267	12606289	3	-	27760321	HT29	viability after 25 days	ATTCCACTATTGGTGATAGTGG	RAF1	ENSG00000132155	0.15831485431075754	[82,64]	[146,104,19]	1	hSpCas9	negative selection	4933735
12612046	12612068	3	-	27760321	HT29	viability after 25 days	TGTAGGTCAATGTGCGAAATGG	RAF1	ENSG00000132155	-0.04740671514157835	[229,179]	[126,376,176]	0	hSpCas9	negative selection	4933736
12618585	12618607	3	-	27760321	HT29	viability after 25 days	AGCGCCGGGCATCAGATGATGG	RAF1	ENSG00000132155	0.933048008112602	[531,414]	[1010,841,1270]	9	hSpCas9	negative selection	4933737
12600387	12600409	3	-	27760321	HT29	viability after 25 days	TTCGAAGTCACAGCGAATCAGG	RAF1	ENSG00000132155	0.44152481155081863	[288,225]	[334,437,432]	5	hSpCas9	negative selection	4933738
12606195	12606217	3	+	27760321	HT29	viability after 22 days	AATTACCTAACAGGCATCCTGG	RAF1	ENSG00000132155	0.13596991205041814	[309,241]	[468,292,285]	1	hSpCas9	negative selection	5017197
12606267	12606289	3	-	27760321	HT29	viability after 22 days	ATTCCACTATTGGTGATAGTGG	RAF1	ENSG00000132155	0.5759395975447819	[82,64]	[119,118,143]	6	hSpCas9	negative selection	5017198
12612046	12612068	3	-	27760321	HT29	viability after 22 days	TGTAGGTCAATGTGCGAAATGG	RAF1	ENSG00000132155	-0.030577298419188326	[229,179]	[164,298,233]	0	hSpCas9	negative selection	5017199
12618585	12618607	3	-	27760321	HT29	viability after 22 days	AGCGCCGGGCATCAGATGATGG	RAF1	ENSG00000132155	0.8297259984691217	[531,414]	[986,873,1057]	8	hSpCas9	negative selection	5017200
12600387	12600409	3	-	27760321	HT29	viability after 22 days	TTCGAAGTCACAGCGAATCAGG	RAF1	ENSG00000132155	0.07986162677737518	[288,225]	[349,280,311]	0	hSpCas9	negative selection	5017201
12606195	12606217	3	+	27760321	HT29	viability after 19 days	AATTACCTAACAGGCATCCTGG	RAF1	ENSG00000132155	-0.11604154528710542	[309,241]	[367,419,100]	-1	hSpCas9	negative selection	5100660
12606267	12606289	3	-	27760321	HT29	viability after 19 days	ATTCCACTATTGGTGATAGTGG	RAF1	ENSG00000132155	-0.3119792588080954	[82,64]	[104,51,51]	-3	hSpCas9	negative selection	5100661
12612046	12612068	3	-	27760321	HT29	viability after 19 days	TGTAGGTCAATGTGCGAAATGG	RAF1	ENSG00000132155	-0.3741730045684031	[229,179]	[357,70,133]	-3	hSpCas9	negative selection	5100662
12618585	12618607	3	-	27760321	HT29	viability after 19 days	AGCGCCGGGCATCAGATGATGG	RAF1	ENSG00000132155	0.2886862571013379	[531,414]	[846,671,490]	2	hSpCas9	negative selection	5100663
12600387	12600409	3	-	27760321	HT29	viability after 19 days	TTCGAAGTCACAGCGAATCAGG	RAF1	ENSG00000132155	0.10708285041666588	[288,225]	[430,231,300]	1	hSpCas9	negative selection	5100664
12606195	12606217	3	+	27760321	HT29	viability after 16 days	AATTACCTAACAGGCATCCTGG	RAF1	ENSG00000132155	0.02269146927799809	[309,241]	[228,390,310]	0	hSpCas9	negative selection	5184123
12606267	12606289	3	-	27760321	HT29	viability after 16 days	ATTCCACTATTGGTGATAGTGG	RAF1	ENSG00000132155	-1.557897538713613	[82,64]	[41,15,27]	-8	hSpCas9	negative selection	5184124
12612046	12612068	3	-	27760321	HT29	viability after 16 days	TGTAGGTCAATGTGCGAAATGG	RAF1	ENSG00000132155	0.04368070161250448	[229,179]	[132,179,387]	0	hSpCas9	negative selection	5184125
12618585	12618607	3	-	27760321	HT29	viability after 16 days	AGCGCCGGGCATCAGATGATGG	RAF1	ENSG00000132155	0.7352430802382555	[531,414]	[759,991,878]	8	hSpCas9	negative selection	5184126
12600387	12600409	3	-	27760321	HT29	viability after 16 days	TTCGAAGTCACAGCGAATCAGG	RAF1	ENSG00000132155	-0.5380891704559082	[288,225]	[149,300,136]	-5	hSpCas9	negative selection	5184127
12606195	12606217	3	+	27760321	HT29	viability after 13 days	AATTACCTAACAGGCATCCTGG	RAF1	ENSG00000132155	-0.14866632021920106	[309,241]	[316,389,166]	-2	hSpCas9	negative selection	5267586
12606267	12606289	3	-	27760321	HT29	viability after 13 days	ATTCCACTATTGGTGATAGTGG	RAF1	ENSG00000132155	0.062375442654169166	[82,64]	[140,91,38]	0	hSpCas9	negative selection	5267587
12612046	12612068	3	-	27760321	HT29	viability after 13 days	TGTAGGTCAATGTGCGAAATGG	RAF1	ENSG00000132155	0.15761824530516955	[229,179]	[347,118,324]	2	hSpCas9	negative selection	5267588
12618585	12618607	3	-	27760321	HT29	viability after 13 days	AGCGCCGGGCATCAGATGATGG	RAF1	ENSG00000132155	0.7644234066417868	[531,414]	[1069,748,976]	8	hSpCas9	negative selection	5267589
12600387	12600409	3	-	27760321	HT29	viability after 13 days	TTCGAAGTCACAGCGAATCAGG	RAF1	ENSG00000132155	-0.36207324272665253	[288,225]	[221,168,301]	-4	hSpCas9	negative selection	5267590
12606195	12606217	3	+	27760321	HT29	viability after 10 days	AATTACCTAACAGGCATCCTGG	RAF1	ENSG00000132155	-0.28035589833786506	[309,241]	[312,306,232]	-4	hSpCas9	negative selection	5351049
12606267	12606289	3	-	27760321	HT29	viability after 10 days	ATTCCACTATTGGTGATAGTGG	RAF1	ENSG00000132155	0.9412114648491208	[82,64]	[113,339,84]	9	hSpCas9	negative selection	5351050
12612046	12612068	3	-	27760321	HT29	viability after 10 days	TGTAGGTCAATGTGCGAAATGG	RAF1	ENSG00000132155	-0.8160330305676977	[229,179]	[61,278,99]	-7	hSpCas9	negative selection	5351051
12618585	12618607	3	-	27760321	HT29	viability after 10 days	AGCGCCGGGCATCAGATGATGG	RAF1	ENSG00000132155	0.25417839680913157	[531,414]	[721,755,639]	3	hSpCas9	negative selection	5351052
12600387	12600409	3	-	27760321	HT29	viability after 10 days	TTCGAAGTCACAGCGAATCAGG	RAF1	ENSG00000132155	-0.38848026003283975	[288,225]	[223,297,216]	-5	hSpCas9	negative selection	5351053
12606195	12606217	3	+	27760321	MOLM13	viability	AATTACCTAACAGGCATCCTGG	RAF1	ENSG00000132155	1.2180794690112149	[419,309]	[612,356]	8	hSpCas9	negative selection	5434512
12606267	12606289	3	-	27760321	MOLM13	viability	ATTCCACTATTGGTGATAGTGG	RAF1	ENSG00000132155	0.1886503093409888	[81,82]	[22,78]	1	hSpCas9	negative selection	5434513
12612046	12612068	3	-	27760321	MOLM13	viability	TGTAGGTCAATGTGCGAAATGG	RAF1	ENSG00000132155	-0.4803397548407252	[256,229]	[59,130]	-3	hSpCas9	negative selection	5434514
12618585	12618607	3	-	27760321	MOLM13	viability	AGCGCCGGGCATCAGATGATGG	RAF1	ENSG00000132155	1.091136831729595	[667,531]	[106,1235]	7	hSpCas9	negative selection	5434515
12600387	12600409	3	-	27760321	MOLM13	viability	TTCGAAGTCACAGCGAATCAGG	RAF1	ENSG00000132155	0.15168960748113464	[363,288]	[83,304]	1	hSpCas9	negative selection	5434516
12663661	12663684	3	-	27661255	K562	viability	GCCAGGCCGTTGTCACCCTGGGG	RAF1	ENSG00000132155	0.32863008533147353	[319,387]	[368,340]	9	dCas9-KRAB	negative selection	5506047
12664057	12664080	3	-	27661255	K562	viability	GTAAGAGGAAAACGATTGTGAGG	RAF1	ENSG00000132155	0.26102715133637266	[1013,1151]	[1070,1002]	8	dCas9-KRAB	negative selection	5506048
12664085	12664108	3	-	27661255	K562	viability	GCTTGGGCCGCCATCTTAGATGG	RAF1	ENSG00000132155	-0.10492750832395914	[219,182]	[147,151]	-4	dCas9-KRAB	negative selection	5506049
12609314	12609337	3	-	27260156	BXPC3	viability	GTAAAAAAGCACGCTTAGATTGG	RAF1	ENSG00000132155	0.399725020132498	[198]	[243,292,224,343]	8	hSpCas9	negative selection	5566220
12618585	12618608	3	-	27260156	BXPC3	viability	CAGCGCCGGGCATCAGATGATGG	RAF1	ENSG00000132155	0.3097295851859717	[201]	[230,359,183,266]	6	hSpCas9	negative selection	5566221
12618681	12618704	3	-	27260156	BXPC3	viability	GCTTGGAAGACGATCAGCAATGG	RAF1	ENSG00000132155	0.37618037490164835	[567]	[649,735,939,769]	7	hSpCas9	negative selection	5566222
12609288	12609311	3	-	27260156	BXPC3	viability	ACTGATGCTGCGTCTTTGATTGG	RAF1	ENSG00000132155	0.24442612469777514	[754]	[834,934,899,1093]	5	hSpCas9	negative selection	5630478
12604174	12604197	3	-	27260156	BXPC3	viability	ATCCACACCTAATGTCCACATGG	RAF1	ENSG00000132155	-0.17378682973486292	[862]	[701,781,808,928]	-4	hSpCas9	negative selection	5630479
12604167	12604190	3	+	27260156	BXPC3	viability	GTGCTGACCATGTGGACATTAGG	RAF1	ENSG00000132155	0.31142982508936157	[425]	[546,427,520,741]	6	hSpCas9	negative selection	5630480
12609314	12609337	3	-	27260156	A673	viability	GTAAAAAAGCACGCTTAGATTGG	RAF1	ENSG00000132155	0.24099735891185503	[198]	[388,277,195,278]	6	hSpCas9	negative selection	5687471
12618585	12618608	3	-	27260156	A673	viability	CAGCGCCGGGCATCAGATGATGG	RAF1	ENSG00000132155	0.203358392661672	[201]	[334,257,232,298]	5	hSpCas9	negative selection	5687472
12618681	12618704	3	-	27260156	A673	viability	GCTTGGAAGACGATCAGCAATGG	RAF1	ENSG00000132155	0.06721329907416118	[567]	[846,606,704,715]	1	hSpCas9	negative selection	5687473
12609288	12609311	3	-	27260156	A673	viability	ACTGATGCTGCGTCTTTGATTGG	RAF1	ENSG00000132155	0.16087676008228247	[754]	[1379,940,871,897]	4	hSpCas9	negative selection	5751729
12604174	12604197	3	-	27260156	A673	viability	ATCCACACCTAATGTCCACATGG	RAF1	ENSG00000132155	-0.2608475783697225	[862]	[873,744,856,992]	-6	hSpCas9	negative selection	5751730
12604167	12604190	3	+	27260156	A673	viability	GTGCTGACCATGTGGACATTAGG	RAF1	ENSG00000132155	-0.020568963477372443	[425]	[540,486,457,536]	0	hSpCas9	negative selection	5751731
12609314	12609337	3	-	27260156	A375	viability	GTAAAAAAGCACGCTTAGATTGG	RAF1	ENSG00000132155	0.39894784333518685	[198]	[357,499,170,231]	6	hSpCas9	negative selection	5808722
12618585	12618608	3	-	27260156	A375	viability	CAGCGCCGGGCATCAGATGATGG	RAF1	ENSG00000132155	0.12616864633953484	[201]	[231,262,391,154]	1	hSpCas9	negative selection	5808723
12618681	12618704	3	-	27260156	A375	viability	GCTTGGAAGACGATCAGCAATGG	RAF1	ENSG00000132155	-0.00450812795095179	[567]	[716,749,512,673]	0	hSpCas9	negative selection	5808724
12609288	12609311	3	-	27260156	A375	viability	ACTGATGCTGCGTCTTTGATTGG	RAF1	ENSG00000132155	0.10667277978817935	[754]	[1036,938,1038,796]	1	hSpCas9	negative selection	5872980
12604174	12604197	3	-	27260156	A375	viability	ATCCACACCTAATGTCCACATGG	RAF1	ENSG00000132155	-0.08992934630447047	[862]	[980,1089,955,795]	-1	hSpCas9	negative selection	5872981
12604167	12604190	3	+	27260156	A375	viability	GTGCTGACCATGTGGACATTAGG	RAF1	ENSG00000132155	0.4469646895395273	[425]	[553,838,698,643]	6	hSpCas9	negative selection	5872982
12609314	12609337	3	-	27260156	COLO741	viability	GTAAAAAAGCACGCTTAGATTGG	RAF1	ENSG00000132155	0.1862490253821092	[198]	[460,291,139]	4	hSpCas9	negative selection	5929973
12618585	12618608	3	-	27260156	COLO741	viability	CAGCGCCGGGCATCAGATGATGG	RAF1	ENSG00000132155	0.25853633704421264	[201]	[368,286,276]	5	hSpCas9	negative selection	5929974
12618681	12618704	3	-	27260156	COLO741	viability	GCTTGGAAGACGATCAGCAATGG	RAF1	ENSG00000132155	-0.01572160578339382	[567]	[881,696,595]	0	hSpCas9	negative selection	5929975
12609288	12609311	3	-	27260156	COLO741	viability	ACTGATGCTGCGTCTTTGATTGG	RAF1	ENSG00000132155	0.34848152436027124	[754]	[1368,1324,1015]	7	hSpCas9	negative selection	5994231
12604174	12604197	3	-	27260156	COLO741	viability	ATCCACACCTAATGTCCACATGG	RAF1	ENSG00000132155	-0.34620248637212425	[862]	[944,895,772]	-6	hSpCas9	negative selection	5994232
12604167	12604190	3	+	27260156	COLO741	viability	GTGCTGACCATGTGGACATTAGG	RAF1	ENSG00000132155	0.09962031048655312	[425]	[727,597,444]	2	hSpCas9	negative selection	5994233
12609314	12609337	3	-	27260156	CAL120	viability	GTAAAAAAGCACGCTTAGATTGG	RAF1	ENSG00000132155	-0.13851785442565134	[198]	[329,213,147]	-2	hSpCas9	negative selection	6051224
12618585	12618608	3	-	27260156	CAL120	viability	CAGCGCCGGGCATCAGATGATGG	RAF1	ENSG00000132155	0.08710773589203824	[201]	[409,176,235]	1	hSpCas9	negative selection	6051225
12618681	12618704	3	-	27260156	CAL120	viability	GCTTGGAAGACGATCAGCAATGG	RAF1	ENSG00000132155	-0.42923786847208417	[567]	[449,461,648]	-6	hSpCas9	negative selection	6051226
12609288	12609311	3	-	27260156	CAL120	viability	ACTGATGCTGCGTCTTTGATTGG	RAF1	ENSG00000132155	0.050890768094054795	[754]	[1098,851,986]	0	hSpCas9	negative selection	6115482
12604174	12604197	3	-	27260156	CAL120	viability	ATCCACACCTAATGTCCACATGG	RAF1	ENSG00000132155	-1.029728226296327	[862]	[607,560,422]	-8	hSpCas9	negative selection	6115483
12604167	12604190	3	+	27260156	CAL120	viability	GTGCTGACCATGTGGACATTAGG	RAF1	ENSG00000132155	0.06261921042147255	[425]	[542,503,610]	0	hSpCas9	negative selection	6115484
12609314	12609337	3	-	27260156	CADOES1	viability	GTAAAAAAGCACGCTTAGATTGG	RAF1	ENSG00000132155	0.4014495539791898	[198]	[198,386,154,236]	6	hSpCas9	negative selection	6172475
12618585	12618608	3	-	27260156	CADOES1	viability	CAGCGCCGGGCATCAGATGATGG	RAF1	ENSG00000132155	0.19632915327139266	[201]	[259,191,266,138]	3	hSpCas9	negative selection	6172476
12618681	12618704	3	-	27260156	CADOES1	viability	GCTTGGAAGACGATCAGCAATGG	RAF1	ENSG00000132155	-0.11930722811231334	[567]	[568,420,494,458]	-2	hSpCas9	negative selection	6172477
12609288	12609311	3	-	27260156	CADOES1	viability	ACTGATGCTGCGTCTTTGATTGG	RAF1	ENSG00000132155	0.3123629170585124	[754]	[765,953,824,945]	5	hSpCas9	negative selection	6236733
12604174	12604197	3	-	27260156	CADOES1	viability	ATCCACACCTAATGTCCACATGG	RAF1	ENSG00000132155	-0.3811492761368254	[862]	[510,554,712,688]	-6	hSpCas9	negative selection	6236734
12604167	12604190	3	+	27260156	CADOES1	viability	GTGCTGACCATGTGGACATTAGG	RAF1	ENSG00000132155	0.039225717867398396	[425]	[440,259,572,351]	0	hSpCas9	negative selection	6236735
12609314	12609337	3	-	27260156	EWS502	viability	GTAAAAAAGCACGCTTAGATTGG	RAF1	ENSG00000132155	0.6598005037935959	[198]	[373,289,208,461]	9	hSpCas9	negative selection	6293726
12618585	12618608	3	-	27260156	EWS502	viability	CAGCGCCGGGCATCAGATGATGG	RAF1	ENSG00000132155	-0.006804762173084011	[201]	[188,182,204,282]	0	hSpCas9	negative selection	6293727
12618681	12618704	3	-	27260156	EWS502	viability	GCTTGGAAGACGATCAGCAATGG	RAF1	ENSG00000132155	-0.2597144891303325	[567]	[457,474,461,627]	-4	hSpCas9	negative selection	6293728
12609288	12609311	3	-	27260156	EWS502	viability	ACTGATGCTGCGTCTTTGATTGG	RAF1	ENSG00000132155	0.27994079181917886	[754]	[844,1042,843,1172]	5	hSpCas9	negative selection	6357984
12604174	12604197	3	-	27260156	EWS502	viability	ATCCACACCTAATGTCCACATGG	RAF1	ENSG00000132155	-0.37746039863492875	[862]	[663,722,679,751]	-6	hSpCas9	negative selection	6357985
12604167	12604190	3	+	27260156	EWS502	viability	GTGCTGACCATGTGGACATTAGG	RAF1	ENSG00000132155	0.40967740591831736	[425]	[506,526,759,618]	7	hSpCas9	negative selection	6357986
12609314	12609337	3	-	27260156	EW8	viability	GTAAAAAAGCACGCTTAGATTGG	RAF1	ENSG00000132155	0.43808181241778155	[198]	[323,197,188,178]	7	hSpCas9	negative selection	6414977
12618585	12618608	3	-	27260156	EW8	viability	CAGCGCCGGGCATCAGATGATGG	RAF1	ENSG00000132155	0.3845203011794128	[201]	[182,212,211,242]	7	hSpCas9	negative selection	6414978
12618681	12618704	3	-	27260156	EW8	viability	GCTTGGAAGACGATCAGCAATGG	RAF1	ENSG00000132155	0.22007321715671857	[567]	[617,377,482,680]	4	hSpCas9	negative selection	6414979
12609288	12609311	3	-	27260156	EW8	viability	ACTGATGCTGCGTCTTTGATTGG	RAF1	ENSG00000132155	0.12481746271847949	[754]	[762,749,673,489]	2	hSpCas9	negative selection	6479235
12604174	12604197	3	-	27260156	EW8	viability	ATCCACACCTAATGTCCACATGG	RAF1	ENSG00000132155	-0.4194381663373551	[862]	[718,517,356,545]	-6	hSpCas9	negative selection	6479236
12604167	12604190	3	+	27260156	EW8	viability	GTGCTGACCATGTGGACATTAGG	RAF1	ENSG00000132155	0.059257683571151465	[425]	[336,270,332,497]	1	hSpCas9	negative selection	6479237
12609314	12609337	3	-	27260156	CORL105	viability	GTAAAAAAGCACGCTTAGATTGG	RAF1	ENSG00000132155	0.776551566013292	[198]	[357,430,435,374]	9	hSpCas9	negative selection	6536228
12618585	12618608	3	-	27260156	CORL105	viability	CAGCGCCGGGCATCAGATGATGG	RAF1	ENSG00000132155	0.4529070626105399	[201]	[281,362,395,262]	8	hSpCas9	negative selection	6536229
12618681	12618704	3	-	27260156	CORL105	viability	GCTTGGAAGACGATCAGCAATGG	RAF1	ENSG00000132155	-0.17122327650417202	[567]	[670,590,677,438]	-3	hSpCas9	negative selection	6536230
12609288	12609311	3	-	27260156	CORL105	viability	ACTGATGCTGCGTCTTTGATTGG	RAF1	ENSG00000132155	0.25925425415111303	[754]	[1060,980,1217,997]	5	hSpCas9	negative selection	6600486
12604174	12604197	3	-	27260156	CORL105	viability	ATCCACACCTAATGTCCACATGG	RAF1	ENSG00000132155	-0.1428930003276362	[862]	[896,780,1263,774]	-3	hSpCas9	negative selection	6600487
12604167	12604190	3	+	27260156	CORL105	viability	GTGCTGACCATGTGGACATTAGG	RAF1	ENSG00000132155	-0.3289538659523429	[425]	[496,255,321,506]	-6	hSpCas9	negative selection	6600488
12609314	12609337	3	-	27260156	HS294T	viability	GTAAAAAAGCACGCTTAGATTGG	RAF1	ENSG00000132155	0.9207891456768649	[198]	[104,160,206,105]	9	hSpCas9	negative selection	6657479
12618585	12618608	3	-	27260156	HS294T	viability	CAGCGCCGGGCATCAGATGATGG	RAF1	ENSG00000132155	0.20215341887335048	[201]	[56,55,82,182]	2	hSpCas9	negative selection	6657480
12618681	12618704	3	-	27260156	HS294T	viability	GCTTGGAAGACGATCAGCAATGG	RAF1	ENSG00000132155	0.43025840956464023	[567]	[176,382,251,395]	6	hSpCas9	negative selection	6657481
12609288	12609311	3	-	27260156	HS294T	viability	ACTGATGCTGCGTCTTTGATTGG	RAF1	ENSG00000132155	0.1870503011104061	[754]	[281,314,347,399]	2	hSpCas9	negative selection	6721737
12604174	12604197	3	-	27260156	HS294T	viability	ATCCACACCTAATGTCCACATGG	RAF1	ENSG00000132155	0.42689764873339486	[862]	[421,350,360,707]	6	hSpCas9	negative selection	6721738
12604167	12604190	3	+	27260156	HS294T	viability	GTGCTGACCATGTGGACATTAGG	RAF1	ENSG00000132155	0.6485834047882391	[425]	[213,274,181,385]	8	hSpCas9	negative selection	6721739
12609314	12609337	3	-	27260156	HCC44	viability	GTAAAAAAGCACGCTTAGATTGG	RAF1	ENSG00000132155	-0.22264908336194145	[198]	[243,186,193,151]	-4	hSpCas9	negative selection	6778730
12618585	12618608	3	-	27260156	HCC44	viability	CAGCGCCGGGCATCAGATGATGG	RAF1	ENSG00000132155	-0.08474088841337402	[201]	[219,173,265,214]	-1	hSpCas9	negative selection	6778731
12618681	12618704	3	-	27260156	HCC44	viability	GCTTGGAAGACGATCAGCAATGG	RAF1	ENSG00000132155	-0.29394461791065124	[567]	[511,545,498,525]	-5	hSpCas9	negative selection	6778732
12609288	12609311	3	-	27260156	HCC44	viability	ACTGATGCTGCGTCTTTGATTGG	RAF1	ENSG00000132155	0.010299474789225438	[754]	[795,768,959,929]	0	hSpCas9	negative selection	6842988
12604174	12604197	3	-	27260156	HCC44	viability	ATCCACACCTAATGTCCACATGG	RAF1	ENSG00000132155	-0.27298984046662944	[862]	[955,781,690,792]	-4	hSpCas9	negative selection	6842989
12604167	12604190	3	+	27260156	HCC44	viability	GTGCTGACCATGTGGACATTAGG	RAF1	ENSG00000132155	0.3563234667756965	[425]	[767,401,650,688]	6	hSpCas9	negative selection	6842990
12609314	12609337	3	-	27260156	G402	viability	GTAAAAAAGCACGCTTAGATTGG	RAF1	ENSG00000132155	0.6625615703473553	[198]	[226,583,290,420]	7	hSpCas9	negative selection	6899981
12618585	12618608	3	-	27260156	G402	viability	CAGCGCCGGGCATCAGATGATGG	RAF1	ENSG00000132155	0.18822520677221255	[201]	[118,420,391,179]	2	hSpCas9	negative selection	6899982
12618681	12618704	3	-	27260156	G402	viability	GCTTGGAAGACGATCAGCAATGG	RAF1	ENSG00000132155	-0.5810677942821485	[567]	[642,476,524,243]	-6	hSpCas9	negative selection	6899983
12609288	12609311	3	-	27260156	G402	viability	ACTGATGCTGCGTCTTTGATTGG	RAF1	ENSG00000132155	0.34363528909474583	[754]	[1230,1009,937,1476]	4	hSpCas9	negative selection	6964239
12604174	12604197	3	-	27260156	G402	viability	ATCCACACCTAATGTCCACATGG	RAF1	ENSG00000132155	-0.34605787526021736	[862]	[986,961,727,671]	-4	hSpCas9	negative selection	6964240
12604167	12604190	3	+	27260156	G402	viability	GTGCTGACCATGTGGACATTAGG	RAF1	ENSG00000132155	-0.03597074992421573	[425]	[569,345,691,421]	0	hSpCas9	negative selection	6964241
12609314	12609337	3	-	27260156	L33	viability	GTAAAAAAGCACGCTTAGATTGG	RAF1	ENSG00000132155	-0.13575928413288274	[198]	[121,59,124,257]	-3	hSpCas9	negative selection	7021232
12618585	12618608	3	-	27260156	L33	viability	CAGCGCCGGGCATCAGATGATGG	RAF1	ENSG00000132155	0.5859057928716092	[201]	[330,137,146,309]	9	hSpCas9	negative selection	7021233
12618681	12618704	3	-	27260156	L33	viability	GCTTGGAAGACGATCAGCAATGG	RAF1	ENSG00000132155	0.165343530201137	[567]	[560,265,428,656]	3	hSpCas9	negative selection	7021234
12609288	12609311	3	-	27260156	L33	viability	ACTGATGCTGCGTCTTTGATTGG	RAF1	ENSG00000132155	0.26423223242994864	[754]	[792,330,620,1039]	5	hSpCas9	negative selection	7085490
12604174	12604197	3	-	27260156	L33	viability	ATCCACACCTAATGTCCACATGG	RAF1	ENSG00000132155	-0.2065972502361052	[862]	[903,299,409,698]	-5	hSpCas9	negative selection	7085491
12604167	12604190	3	+	27260156	L33	viability	GTGCTGACCATGTGGACATTAGG	RAF1	ENSG00000132155	0.2367438603503665	[425]	[558,226,274,455]	5	hSpCas9	negative selection	7085492
12609314	12609337	3	-	27260156	K562	viability	GTAAAAAAGCACGCTTAGATTGG	RAF1	ENSG00000132155	0.622418565438805	[198]	[501,107,303,191]	7	hSpCas9	negative selection	7142483
12618585	12618608	3	-	27260156	K562	viability	CAGCGCCGGGCATCAGATGATGG	RAF1	ENSG00000132155	0.2352254414146142	[201]	[302,170,346,46]	3	hSpCas9	negative selection	7142484
12618681	12618704	3	-	27260156	K562	viability	GCTTGGAAGACGATCAGCAATGG	RAF1	ENSG00000132155	-1.0854657592510626	[567]	[279,350,131,199]	-8	hSpCas9	negative selection	7142485
12609288	12609311	3	-	27260156	K562	viability	ACTGATGCTGCGTCTTTGATTGG	RAF1	ENSG00000132155	0.04340983763699624	[754]	[553,587,1009,600]	0	hSpCas9	negative selection	7206741
12604174	12604197	3	-	27260156	K562	viability	ATCCACACCTAATGTCCACATGG	RAF1	ENSG00000132155	-0.5699598367815152	[862]	[586,545,383,547]	-6	hSpCas9	negative selection	7206742
12604167	12604190	3	+	27260156	K562	viability	GTGCTGACCATGTGGACATTAGG	RAF1	ENSG00000132155	-0.13647481121907243	[425]	[481,364,302,247]	-2	hSpCas9	negative selection	7206743
12609314	12609337	3	-	27260156	HT29	viability	GTAAAAAAGCACGCTTAGATTGG	RAF1	ENSG00000132155	0.2518572266184863	[198]	[218,365,336,235]	5	hSpCas9	negative selection	7263734
12618585	12618608	3	-	27260156	HT29	viability	CAGCGCCGGGCATCAGATGATGG	RAF1	ENSG00000132155	0.14559167998804723	[201]	[379,197,267,243]	3	hSpCas9	negative selection	7263735
12618681	12618704	3	-	27260156	HT29	viability	GCTTGGAAGACGATCAGCAATGG	RAF1	ENSG00000132155	0.08650185896111778	[567]	[826,778,694,647]	1	hSpCas9	negative selection	7263736
12609288	12609311	3	-	27260156	HT29	viability	ACTGATGCTGCGTCTTTGATTGG	RAF1	ENSG00000132155	0.2353697861984997	[754]	[1074,1080,1090,1067]	4	hSpCas9	negative selection	7327992
12604174	12604197	3	-	27260156	HT29	viability	ATCCACACCTAATGTCCACATGG	RAF1	ENSG00000132155	-0.23177654731212372	[862]	[813,990,769,982]	-4	hSpCas9	negative selection	7327993
12604167	12604190	3	+	27260156	HT29	viability	GTGCTGACCATGTGGACATTAGG	RAF1	ENSG00000132155	-0.06965581257441794	[425]	[541,426,512,486]	-1	hSpCas9	negative selection	7327994
12609314	12609337	3	-	27260156	MHHES1	viability	GTAAAAAAGCACGCTTAGATTGG	RAF1	ENSG00000132155	0.2432582977786425	[198]	[209,254,278,295]	4	hSpCas9	negative selection	7384985
12618585	12618608	3	-	27260156	MHHES1	viability	CAGCGCCGGGCATCAGATGATGG	RAF1	ENSG00000132155	0.21115892409296233	[201]	[346,216,237,252]	4	hSpCas9	negative selection	7384986
12618681	12618704	3	-	27260156	MHHES1	viability	GCTTGGAAGACGATCAGCAATGG	RAF1	ENSG00000132155	0.028445363894248787	[567]	[763,658,714,505]	0	hSpCas9	negative selection	7384987
12609288	12609311	3	-	27260156	MHHES1	viability	ACTGATGCTGCGTCTTTGATTGG	RAF1	ENSG00000132155	0.022369429494926263	[754]	[1283,938,864,492]	0	hSpCas9	negative selection	7449243
12604174	12604197	3	-	27260156	MHHES1	viability	ATCCACACCTAATGTCCACATGG	RAF1	ENSG00000132155	-0.28365390116386036	[862]	[1396,533,864,496]	-5	hSpCas9	negative selection	7449244
12604167	12604190	3	+	27260156	MHHES1	viability	GTGCTGACCATGTGGACATTAGG	RAF1	ENSG00000132155	0.11914081253765664	[425]	[577,487,576,449]	2	hSpCas9	negative selection	7449245
12609314	12609337	3	-	27260156	MEWO	viability	GTAAAAAAGCACGCTTAGATTGG	RAF1	ENSG00000132155	0.3052764132794549	[198]	[326,205,175]	6	hSpCas9	negative selection	7506236
12618585	12618608	3	-	27260156	MEWO	viability	CAGCGCCGGGCATCAGATGATGG	RAF1	ENSG00000132155	-0.4651615096072206	[201]	[153,131,127]	-7	hSpCas9	negative selection	7506237
12618681	12618704	3	-	27260156	MEWO	viability	GCTTGGAAGACGATCAGCAATGG	RAF1	ENSG00000132155	-0.1795668158042541	[567]	[541,391,487]	-4	hSpCas9	negative selection	7506238
12609288	12609311	3	-	27260156	MEWO	viability	ACTGATGCTGCGTCTTTGATTGG	RAF1	ENSG00000132155	0.13961148494238462	[754]	[903,690,763]	3	hSpCas9	negative selection	7570494
12604174	12604197	3	-	27260156	MEWO	viability	ATCCACACCTAATGTCCACATGG	RAF1	ENSG00000132155	-0.6594923659476787	[862]	[621,477,454]	-8	hSpCas9	negative selection	7570495
12604167	12604190	3	+	27260156	MEWO	viability	GTGCTGACCATGTGGACATTAGG	RAF1	ENSG00000132155	-0.14953522771074282	[425]	[451,318,324]	-3	hSpCas9	negative selection	7570496
12609314	12609337	3	-	27260156	LNCAPCLONEFGC	viability	GTAAAAAAGCACGCTTAGATTGG	RAF1	ENSG00000132155	0.6389725387662808	[198]	[264,418,254,170]	8	hSpCas9	negative selection	7627487
12618585	12618608	3	-	27260156	LNCAPCLONEFGC	viability	CAGCGCCGGGCATCAGATGATGG	RAF1	ENSG00000132155	0.7057245943897303	[201]	[171,450,298,263]	9	hSpCas9	negative selection	7627488
12618681	12618704	3	-	27260156	LNCAPCLONEFGC	viability	GCTTGGAAGACGATCAGCAATGG	RAF1	ENSG00000132155	-0.1652856281172103	[567]	[375,385,556,536]	-3	hSpCas9	negative selection	7627489
12609288	12609311	3	-	27260156	LNCAPCLONEFGC	viability	ACTGATGCTGCGTCTTTGATTGG	RAF1	ENSG00000132155	0.427060045073661	[754]	[925,703,1211,892]	6	hSpCas9	negative selection	7691745
12604174	12604197	3	-	27260156	LNCAPCLONEFGC	viability	ATCCACACCTAATGTCCACATGG	RAF1	ENSG00000132155	-0.46632306373706917	[862]	[474,572,617,605]	-6	hSpCas9	negative selection	7691746
12604167	12604190	3	+	27260156	LNCAPCLONEFGC	viability	GTGCTGACCATGTGGACATTAGG	RAF1	ENSG00000132155	-0.014997669491306959	[425]	[279,358,483,422]	0	hSpCas9	negative selection	7691747
12609314	12609337	3	-	27260156	PANC0327	viability	GTAAAAAAGCACGCTTAGATTGG	RAF1	ENSG00000132155	0.35080413060436255	[198]	[187,222,272,214]	5	hSpCas9	negative selection	7748738
12618585	12618608	3	-	27260156	PANC0327	viability	CAGCGCCGGGCATCAGATGATGG	RAF1	ENSG00000132155	0.6864831011351314	[201]	[343,238,295,286]	8	hSpCas9	negative selection	7748739
12618681	12618704	3	-	27260156	PANC0327	viability	GCTTGGAAGACGATCAGCAATGG	RAF1	ENSG00000132155	-0.47056489176409455	[567]	[453,431,309,258]	-6	hSpCas9	negative selection	7748740
12609288	12609311	3	-	27260156	PANC0327	viability	ACTGATGCTGCGTCTTTGATTGG	RAF1	ENSG00000132155	-0.02081486279878675	[754]	[563,485,866,741]	0	hSpCas9	negative selection	7812996
12604174	12604197	3	-	27260156	PANC0327	viability	ATCCACACCTAATGTCCACATGG	RAF1	ENSG00000132155	-0.31938788111756067	[862]	[765,767,572,342]	-5	hSpCas9	negative selection	7812997
12604167	12604190	3	+	27260156	PANC0327	viability	GTGCTGACCATGTGGACATTAGG	RAF1	ENSG00000132155	-0.17019350224156718	[425]	[153,396,213,556]	-3	hSpCas9	negative selection	7812998
12609314	12609337	3	-	27260156	NCIH2009	viability	GTAAAAAAGCACGCTTAGATTGG	RAF1	ENSG00000132155	0.27392367120491634	[198]	[480,256,299]	4	hSpCas9	negative selection	7869989
12618585	12618608	3	-	27260156	NCIH2009	viability	CAGCGCCGGGCATCAGATGATGG	RAF1	ENSG00000132155	0.2168686129415336	[201]	[405,265,327]	3	hSpCas9	negative selection	7869990
12618681	12618704	3	-	27260156	NCIH2009	viability	GCTTGGAAGACGATCAGCAATGG	RAF1	ENSG00000132155	-1.1206005485173551	[567]	[437,294,376]	-8	hSpCas9	negative selection	7869991
12609288	12609311	3	-	27260156	NCIH2009	viability	ACTGATGCTGCGTCTTTGATTGG	RAF1	ENSG00000132155	-0.402738270901531	[754]	[1168,617,681]	-5	hSpCas9	negative selection	7934247
12604174	12604197	3	-	27260156	NCIH2009	viability	ATCCACACCTAATGTCCACATGG	RAF1	ENSG00000132155	-0.8139339590236705	[862]	[759,579,732]	-7	hSpCas9	negative selection	7934248
12604167	12604190	3	+	27260156	NCIH2009	viability	GTGCTGACCATGTGGACATTAGG	RAF1	ENSG00000132155	-0.8266428783434783	[425]	[421,240,361]	-7	hSpCas9	negative selection	7934249
12609314	12609337	3	-	27260156	NCIH1373	viability	GTAAAAAAGCACGCTTAGATTGG	RAF1	ENSG00000132155	0.5448481109693033	[198]	[351,323,444,44]	5	hSpCas9	negative selection	7991240
12618585	12618608	3	-	27260156	NCIH1373	viability	CAGCGCCGGGCATCAGATGATGG	RAF1	ENSG00000132155	0.22868843019714657	[201]	[364,100,239,103]	2	hSpCas9	negative selection	7991241
12618681	12618704	3	-	27260156	NCIH1373	viability	GCTTGGAAGACGATCAGCAATGG	RAF1	ENSG00000132155	-0.821364068273407	[567]	[386,202,260,164]	-7	hSpCas9	negative selection	7991242
12609288	12609311	3	-	27260156	NCIH1373	viability	ACTGATGCTGCGTCTTTGATTGG	RAF1	ENSG00000132155	0.21259000954113005	[754]	[1175,660,1215,241]	2	hSpCas9	negative selection	8055498
12604174	12604197	3	-	27260156	NCIH1373	viability	ATCCACACCTAATGTCCACATGG	RAF1	ENSG00000132155	-0.8076052981391366	[862]	[593,447,573,160]	-7	hSpCas9	negative selection	8055499
12604167	12604190	3	+	27260156	NCIH1373	viability	GTGCTGACCATGTGGACATTAGG	RAF1	ENSG00000132155	-0.33756024437513865	[425]	[577,173,243,152]	-3	hSpCas9	negative selection	8055500
12609314	12609337	3	-	27260156	PATU8902	viability	GTAAAAAAGCACGCTTAGATTGG	RAF1	ENSG00000132155	0.22091419352043862	[198]	[636,206,169,308]	2	hSpCas9	negative selection	8112491
12618585	12618608	3	-	27260156	PATU8902	viability	CAGCGCCGGGCATCAGATGATGG	RAF1	ENSG00000132155	0.06619700048135768	[201]	[494,185,260,231]	0	hSpCas9	negative selection	8112492
12618681	12618704	3	-	27260156	PATU8902	viability	GCTTGGAAGACGATCAGCAATGG	RAF1	ENSG00000132155	-1.7276124121561294	[567]	[344,134,43,510]	-8	hSpCas9	negative selection	8112493
12609288	12609311	3	-	27260156	PATU8902	viability	ACTGATGCTGCGTCTTTGATTGG	RAF1	ENSG00000132155	-1.274379549988694	[754]	[339,514,386,516]	-8	hSpCas9	negative selection	8176749
12604174	12604197	3	-	27260156	PATU8902	viability	ATCCACACCTAATGTCCACATGG	RAF1	ENSG00000132155	-0.7673737882762766	[862]	[590,555,731,964]	-6	hSpCas9	negative selection	8176750
12604167	12604190	3	+	27260156	PATU8902	viability	GTGCTGACCATGTGGACATTAGG	RAF1	ENSG00000132155	-1.5418745754629817	[425]	[280,294,111,140]	-8	hSpCas9	negative selection	8176751
12609314	12609337	3	-	27260156	PANC1	viability	GTAAAAAAGCACGCTTAGATTGG	RAF1	ENSG00000132155	0.1806436638241926	[198]	[99,150,261,243]	3	hSpCas9	negative selection	8233742
12618585	12618608	3	-	27260156	PANC1	viability	CAGCGCCGGGCATCAGATGATGG	RAF1	ENSG00000132155	0.5372552089207532	[201]	[171,384,349,143]	8	hSpCas9	negative selection	8233743
12618681	12618704	3	-	27260156	PANC1	viability	GCTTGGAAGACGATCAGCAATGG	RAF1	ENSG00000132155	-0.7876959452321978	[567]	[193,285,273,360]	-8	hSpCas9	negative selection	8233744
12609288	12609311	3	-	27260156	PANC1	viability	ACTGATGCTGCGTCTTTGATTGG	RAF1	ENSG00000132155	0.18065257527977518	[754]	[777,747,920,519]	3	hSpCas9	negative selection	8298000
12604174	12604197	3	-	27260156	PANC1	viability	ATCCACACCTAATGTCCACATGG	RAF1	ENSG00000132155	-0.622936503962735	[862]	[553,399,590,372]	-7	hSpCas9	negative selection	8298001
12604167	12604190	3	+	27260156	PANC1	viability	GTGCTGACCATGTGGACATTAGG	RAF1	ENSG00000132155	-0.21803432966088013	[425]	[301,484,256,253]	-4	hSpCas9	negative selection	8298002
12609314	12609337	3	-	27260156	PANC0813	viability	GTAAAAAAGCACGCTTAGATTGG	RAF1	ENSG00000132155	0.48976165012653183	[198]	[341,338,328,304]	7	hSpCas9	negative selection	8354993
12618585	12618608	3	-	27260156	PANC0813	viability	CAGCGCCGGGCATCAGATGATGG	RAF1	ENSG00000132155	0.16014162714274716	[201]	[291,200,307,261]	2	hSpCas9	negative selection	8354994
12618681	12618704	3	-	27260156	PANC0813	viability	GCTTGGAAGACGATCAGCAATGG	RAF1	ENSG00000132155	-0.7331974564415192	[567]	[453,275,270,596]	-8	hSpCas9	negative selection	8354995
12609288	12609311	3	-	27260156	PANC0813	viability	ACTGATGCTGCGTCTTTGATTGG	RAF1	ENSG00000132155	-0.619472760804112	[754]	[795,518,406,603]	-7	hSpCas9	negative selection	8419251
12604174	12604197	3	-	27260156	PANC0813	viability	ATCCACACCTAATGTCCACATGG	RAF1	ENSG00000132155	-0.9612404432793542	[862]	[479,562,394,632]	-8	hSpCas9	negative selection	8419252
12604167	12604190	3	+	27260156	PANC0813	viability	GTGCTGACCATGTGGACATTAGG	RAF1	ENSG00000132155	-0.7511168787924306	[425]	[357,265,302,268]	-8	hSpCas9	negative selection	8419253
12609314	12609337	3	-	27260156	RDES	viability	GTAAAAAAGCACGCTTAGATTGG	RAF1	ENSG00000132155	0.48507128595095106	[198]	[334,231,334,383]	7	hSpCas9	negative selection	8476244
12618585	12618608	3	-	27260156	RDES	viability	CAGCGCCGGGCATCAGATGATGG	RAF1	ENSG00000132155	0.047053603532443145	[201]	[270,151,191,353]	0	hSpCas9	negative selection	8476245
12618681	12618704	3	-	27260156	RDES	viability	GCTTGGAAGACGATCAGCAATGG	RAF1	ENSG00000132155	-0.00994064024881497	[567]	[515,579,731,810]	0	hSpCas9	negative selection	8476246
12609288	12609311	3	-	27260156	RDES	viability	ACTGATGCTGCGTCTTTGATTGG	RAF1	ENSG00000132155	0.48703061538245773	[754]	[965,921,1509,1584]	7	hSpCas9	negative selection	8540502
12604174	12604197	3	-	27260156	RDES	viability	ATCCACACCTAATGTCCACATGG	RAF1	ENSG00000132155	-0.2102701063972119	[862]	[741,678,900,1175]	-4	hSpCas9	negative selection	8540503
12604167	12604190	3	+	27260156	RDES	viability	GTGCTGACCATGTGGACATTAGG	RAF1	ENSG00000132155	0.37613816143612494	[425]	[509,624,822,594]	6	hSpCas9	negative selection	8540504
12609314	12609337	3	-	27260156	PC3	viability	GTAAAAAAGCACGCTTAGATTGG	RAF1	ENSG00000132155	0.2149619661793385	[198]	[194,150,382,242]	5	hSpCas9	negative selection	8597495
12618585	12618608	3	-	27260156	PC3	viability	CAGCGCCGGGCATCAGATGATGG	RAF1	ENSG00000132155	-0.21569314358932545	[201]	[81,232,239,187]	-5	hSpCas9	negative selection	8597496
12618681	12618704	3	-	27260156	PC3	viability	GCTTGGAAGACGATCAGCAATGG	RAF1	ENSG00000132155	0.005606255502428492	[567]	[328,515,1023,641]	0	hSpCas9	negative selection	8597497
12609288	12609311	3	-	27260156	PC3	viability	ACTGATGCTGCGTCTTTGATTGG	RAF1	ENSG00000132155	0.4031693936278893	[754]	[607,973,1721,1037]	8	hSpCas9	negative selection	8661753
12604174	12604197	3	-	27260156	PC3	viability	ATCCACACCTAATGTCCACATGG	RAF1	ENSG00000132155	-0.2638667417342394	[862]	[518,745,1047,684]	-5	hSpCas9	negative selection	8661754
12604167	12604190	3	+	27260156	PC3	viability	GTGCTGACCATGTGGACATTAGG	RAF1	ENSG00000132155	0.12013554842933546	[425]	[224,551,844,433]	2	hSpCas9	negative selection	8661755
12609314	12609337	3	-	27260156	PATU8988T	viability	GTAAAAAAGCACGCTTAGATTGG	RAF1	ENSG00000132155	0.21127818248739771	[198]	[137,190,401,147]	3	hSpCas9	negative selection	8718746
12618585	12618608	3	-	27260156	PATU8988T	viability	CAGCGCCGGGCATCAGATGATGG	RAF1	ENSG00000132155	0.7166463218579361	[201]	[229,295,384,372]	9	hSpCas9	negative selection	8718747
12618681	12618704	3	-	27260156	PATU8988T	viability	GCTTGGAAGACGATCAGCAATGG	RAF1	ENSG00000132155	-0.5843592785938765	[567]	[289,441,452,277]	-7	hSpCas9	negative selection	8718748
12609288	12609311	3	-	27260156	PATU8988T	viability	ACTGATGCTGCGTCTTTGATTGG	RAF1	ENSG00000132155	-0.2523902870812321	[754]	[271,772,697,729]	-4	hSpCas9	negative selection	8783004
12604174	12604197	3	-	27260156	PATU8988T	viability	ATCCACACCTAATGTCCACATGG	RAF1	ENSG00000132155	-0.3346078682674428	[862]	[758,613,522,753]	-5	hSpCas9	negative selection	8783005
12604167	12604190	3	+	27260156	PATU8988T	viability	GTGCTGACCATGTGGACATTAGG	RAF1	ENSG00000132155	-0.3865437531100463	[425]	[558,185,288,204]	-6	hSpCas9	negative selection	8783006
12609314	12609337	3	-	27260156	T47D	viability	GTAAAAAAGCACGCTTAGATTGG	RAF1	ENSG00000132155	0.41382376430446965	[198]	[291,347,246,346]	8	hSpCas9	negative selection	8839997
12618585	12618608	3	-	27260156	T47D	viability	CAGCGCCGGGCATCAGATGATGG	RAF1	ENSG00000132155	0.3292457842576618	[201]	[340,263,236,345]	7	hSpCas9	negative selection	8839998
12618681	12618704	3	-	27260156	T47D	viability	GCTTGGAAGACGATCAGCAATGG	RAF1	ENSG00000132155	0.07587608440226679	[567]	[630,639,666,861]	1	hSpCas9	negative selection	8839999
12609288	12609311	3	-	27260156	T47D	viability	ACTGATGCTGCGTCTTTGATTGG	RAF1	ENSG00000132155	0.20436713611099422	[754]	[1037,1021,922,1072]	4	hSpCas9	negative selection	8904255
12604174	12604197	3	-	27260156	T47D	viability	ATCCACACCTAATGTCCACATGG	RAF1	ENSG00000132155	-0.38342652482440154	[862]	[799,653,835,802]	-7	hSpCas9	negative selection	8904256
12604167	12604190	3	+	27260156	T47D	viability	GTGCTGACCATGTGGACATTAGG	RAF1	ENSG00000132155	-0.1944738686509759	[425]	[477,452,392,408]	-4	hSpCas9	negative selection	8904257
12609314	12609337	3	-	27260156	SU8686	viability	GTAAAAAAGCACGCTTAGATTGG	RAF1	ENSG00000132155	0.45999204941201743	[198]	[250,181,321,357]	7	hSpCas9	negative selection	8961248
12618585	12618608	3	-	27260156	SU8686	viability	CAGCGCCGGGCATCAGATGATGG	RAF1	ENSG00000132155	-0.01756404674537082	[201]	[175,190,248,174]	0	hSpCas9	negative selection	8961249
12618681	12618704	3	-	27260156	SU8686	viability	GCTTGGAAGACGATCAGCAATGG	RAF1	ENSG00000132155	0.05761669551129295	[567]	[641,539,471,700]	1	hSpCas9	negative selection	8961250
12609288	12609311	3	-	27260156	SU8686	viability	ACTGATGCTGCGTCTTTGATTGG	RAF1	ENSG00000132155	0.2819919472722755	[754]	[610,837,1074,1205]	5	hSpCas9	negative selection	9025506
12604174	12604197	3	-	27260156	SU8686	viability	ATCCACACCTAATGTCCACATGG	RAF1	ENSG00000132155	-0.20443016765458655	[862]	[904,499,715,877]	-4	hSpCas9	negative selection	9025507
12604167	12604190	3	+	27260156	SU8686	viability	GTGCTGACCATGTGGACATTAGG	RAF1	ENSG00000132155	0.45161474999673035	[425]	[466,432,635,846]	7	hSpCas9	negative selection	9025508
12609314	12609337	3	-	27260156	SKES1	viability	GTAAAAAAGCACGCTTAGATTGG	RAF1	ENSG00000132155	0.19781674304601315	[198]	[274,189,212,231]	4	hSpCas9	negative selection	9082499
12618585	12618608	3	-	27260156	SKES1	viability	CAGCGCCGGGCATCAGATGATGG	RAF1	ENSG00000132155	0.5569045420723895	[201]	[533,262,204,219]	9	hSpCas9	negative selection	9082500
12618681	12618704	3	-	27260156	SKES1	viability	GCTTGGAAGACGATCAGCAATGG	RAF1	ENSG00000132155	0.1225363149695588	[567]	[527,675,641,609]	2	hSpCas9	negative selection	9082501
12609288	12609311	3	-	27260156	SKES1	viability	ACTGATGCTGCGTCTTTGATTGG	RAF1	ENSG00000132155	0.0421803516709407	[754]	[846,761,741,753]	0	hSpCas9	negative selection	9146757
12604174	12604197	3	-	27260156	SKES1	viability	ATCCACACCTAATGTCCACATGG	RAF1	ENSG00000132155	-0.33085254984936485	[862]	[677,682,637,725]	-6	hSpCas9	negative selection	9146758
12604167	12604190	3	+	27260156	SKES1	viability	GTGCTGACCATGTGGACATTAGG	RAF1	ENSG00000132155	0.208273196694834	[425]	[595,537,442,411]	4	hSpCas9	negative selection	9146759
12609314	12609337	3	-	27260156	TOV112D	viability	GTAAAAAAGCACGCTTAGATTGG	RAF1	ENSG00000132155	0.01684236749105894	[198]	[221,225,92,270]	0	hSpCas9	negative selection	9203750
12618585	12618608	3	-	27260156	TOV112D	viability	CAGCGCCGGGCATCAGATGATGG	RAF1	ENSG00000132155	0.7980083473356508	[201]	[468,263,246,412]	9	hSpCas9	negative selection	9203751
12618681	12618704	3	-	27260156	TOV112D	viability	GCTTGGAAGACGATCAGCAATGG	RAF1	ENSG00000132155	0.08524889922236784	[567]	[776,652,448,561]	1	hSpCas9	negative selection	9203752
12609288	12609311	3	-	27260156	TOV112D	viability	ACTGATGCTGCGTCTTTGATTGG	RAF1	ENSG00000132155	-0.02007404012034053	[754]	[808,953,665,612]	0	hSpCas9	negative selection	9268008
12604174	12604197	3	-	27260156	TOV112D	viability	ATCCACACCTAATGTCCACATGG	RAF1	ENSG00000132155	-0.07767209373946027	[862]	[723,1078,753,774]	-1	hSpCas9	negative selection	9268009
12604167	12604190	3	+	27260156	TOV112D	viability	GTGCTGACCATGTGGACATTAGG	RAF1	ENSG00000132155	0.421802455324481	[425]	[800,644,425,453]	7	hSpCas9	negative selection	9268010
12609314	12609337	3	-	27260156	TC71	viability	GTAAAAAAGCACGCTTAGATTGG	RAF1	ENSG00000132155	-0.04892172166737341	[198]	[180,194,213,236]	-1	hSpCas9	negative selection	9325001
12618585	12618608	3	-	27260156	TC71	viability	CAGCGCCGGGCATCAGATGATGG	RAF1	ENSG00000132155	0.08528754099613067	[201]	[239,263,156,261]	2	hSpCas9	negative selection	9325002
12618681	12618704	3	-	27260156	TC71	viability	GCTTGGAAGACGATCAGCAATGG	RAF1	ENSG00000132155	0.05849163889501813	[567]	[655,793,481,606]	1	hSpCas9	negative selection	9325003
12609288	12609311	3	-	27260156	TC71	viability	ACTGATGCTGCGTCTTTGATTGG	RAF1	ENSG00000132155	0.07186055558422166	[754]	[881,800,730,1000]	1	hSpCas9	negative selection	9389259
12604174	12604197	3	-	27260156	TC71	viability	ATCCACACCTAATGTCCACATGG	RAF1	ENSG00000132155	-0.4408002390693211	[862]	[638,721,633,736]	-8	hSpCas9	negative selection	9389260
12604167	12604190	3	+	27260156	TC71	viability	GTGCTGACCATGTGGACATTAGG	RAF1	ENSG00000132155	-0.11065154807699598	[425]	[387,425,428,450]	-3	hSpCas9	negative selection	9389261
12609314	12609337	3	-	27260156	TC32	viability	GTAAAAAAGCACGCTTAGATTGG	RAF1	ENSG00000132155	0.24519706546481623	[198]	[189,80,500,208]	4	hSpCas9	negative selection	9446252
12618585	12618608	3	-	27260156	TC32	viability	CAGCGCCGGGCATCAGATGATGG	RAF1	ENSG00000132155	-0.04624531940867538	[201]	[138,124,332,181]	-1	hSpCas9	negative selection	9446253
12618681	12618704	3	-	27260156	TC32	viability	GCTTGGAAGACGATCAGCAATGG	RAF1	ENSG00000132155	-0.034261484924410335	[567]	[501,346,777,541]	0	hSpCas9	negative selection	9446254
12609288	12609311	3	-	27260156	TC32	viability	ACTGATGCTGCGTCTTTGATTGG	RAF1	ENSG00000132155	0.09013061727483629	[754]	[581,775,888,762]	1	hSpCas9	negative selection	9510510
12604174	12604197	3	-	27260156	TC32	viability	ATCCACACCTAATGTCCACATGG	RAF1	ENSG00000132155	-0.16900482995244304	[862]	[494,806,788,756]	-3	hSpCas9	negative selection	9510511
12604167	12604190	3	+	27260156	TC32	viability	GTGCTGACCATGTGGACATTAGG	RAF1	ENSG00000132155	0.02807283190822589	[425]	[249,397,449,548]	0	hSpCas9	negative selection	9510512
12590899	12590922	3	-	27869803	HPAFII	viability after 27 days	ACCTGGCAATTGTGACCCAGTGG	RAF1	ENSG00000132155	-1.494761845526374	[95]	[12,21,NaN]	-7	hSpCas9	negative selection	9582361
12600187	12600210	3	-	27869803	HPAFII	viability after 27 days	CGTGCCAGCACAAAGAGAGCGGG	RAF1	ENSG00000132155	-1.0783934466689291	[615]	[142,161,NaN]	-6	hSpCas9	negative selection	9582365
12603510	12603533	3	-	27869803	HPAFII	viability after 27 days	CAACCTGAGTGCTTCTCCCAGGG	RAF1	ENSG00000132155	-0.34904044642377363	[160]	[24,100,NaN]	-3	hSpCas9	negative selection	9582368
12604220	12604243	3	+	27869803	HPAFII	viability after 27 days	GGAACCTTCAGATGAGGGACTGG	RAF1	ENSG00000132155	0.14666267531334143	[203]	[163,80,NaN]	1	hSpCas9	negative selection	9582371
12608851	12608874	3	+	27869803	HPAFII	viability after 27 days	GACATCGAAATCCATTGAGCAGG	RAF1	ENSG00000132155	-2.386000297798139	[140]	[11,15,NaN]	-8	hSpCas9	negative selection	9582372
12618599	12618622	3	-	27869803	HPAFII	viability after 27 days	AGCAGTTTGGCTATCAGCGCCGG	RAF1	ENSG00000132155	-1.6260416440434067	[355]	[82,41,NaN]	-7	hSpCas9	negative selection	9582374
12590899	12590922	3	-	27869803	HPAFII	viability after 15 days	ACCTGGCAATTGTGACCCAGTGG	RAF1	ENSG00000132155	-0.4845211766134281	[95]	[164,16,NaN]	-5	hSpCas9	negative selection	9664810
12600187	12600210	3	-	27869803	HPAFII	viability after 15 days	CGTGCCAGCACAAAGAGAGCGGG	RAF1	ENSG00000132155	-0.7061156697204404	[615]	[464,368,NaN]	-6	hSpCas9	negative selection	9664814
12603510	12603533	3	-	27869803	HPAFII	viability after 15 days	CAACCTGAGTGCTTCTCCCAGGG	RAF1	ENSG00000132155	-0.10887464481495357	[160]	[202,133,NaN]	-1	hSpCas9	negative selection	9664817
12604220	12604243	3	+	27869803	HPAFII	viability after 15 days	GGAACCTTCAGATGAGGGACTGG	RAF1	ENSG00000132155	0.2562838016653301	[203]	[251,267,NaN]	3	hSpCas9	negative selection	9664820
12608851	12608874	3	+	27869803	HPAFII	viability after 15 days	GACATCGAAATCCATTGAGCAGG	RAF1	ENSG00000132155	0.699703636203396	[140]	[300,211,NaN]	7	hSpCas9	negative selection	9664821
12618599	12618622	3	-	27869803	HPAFII	viability after 15 days	AGCAGTTTGGCTATCAGCGCCGG	RAF1	ENSG00000132155	-0.2980602475631916	[355]	[370,273,NaN]	-3	hSpCas9	negative selection	9664823
12590899	12590922	3	-	27869803	ASPC1	viability after 36 days	ACCTGGCAATTGTGACCCAGTGG	RAF1	ENSG00000132155	-1.60356224514502	[326]	[111,5,9]	-8	hSpCas9	negative selection	9747259
12600187	12600210	3	-	27869803	ASPC1	viability after 36 days	CGTGCCAGCACAAAGAGAGCGGG	RAF1	ENSG00000132155	-0.15574786139279195	[1076]	[354,365,298]	-2	hSpCas9	negative selection	9747263
12603510	12603533	3	-	27869803	ASPC1	viability after 36 days	CAACCTGAGTGCTTCTCCCAGGG	RAF1	ENSG00000132155	0.9685714562843435	[425]	[214,182,426]	8	hSpCas9	negative selection	9747266
12604220	12604243	3	+	27869803	ASPC1	viability after 36 days	GGAACCTTCAGATGAGGGACTGG	RAF1	ENSG00000132155	-0.46193442866708445	[394]	[11,75,179]	-5	hSpCas9	negative selection	9747269
12608851	12608874	3	+	27869803	ASPC1	viability after 36 days	GACATCGAAATCCATTGAGCAGG	RAF1	ENSG00000132155	-0.6969123045691172	[284]	[5,114,56]	-6	hSpCas9	negative selection	9747270
12618599	12618622	3	-	27869803	ASPC1	viability after 36 days	AGCAGTTTGGCTATCAGCGCCGG	RAF1	ENSG00000132155	-0.7070704714477893	[912]	[219,296,94]	-6	hSpCas9	negative selection	9747272
12590899	12590922	3	-	27869803	PATU8988S	viability after 35 days	ACCTGGCAATTGTGACCCAGTGG	RAF1	ENSG00000132155	-1.771339162413249	[270]	[19,43,NaN]	-8	hSpCas9	negative selection	9829708
12600187	12600210	3	-	27869803	PATU8988S	viability after 35 days	CGTGCCAGCACAAAGAGAGCGGG	RAF1	ENSG00000132155	-1.3149640169125596	[966]	[172,139,NaN]	-8	hSpCas9	negative selection	9829712
12603510	12603533	3	-	27869803	PATU8988S	viability after 35 days	CAACCTGAGTGCTTCTCCCAGGG	RAF1	ENSG00000132155	-0.02688837649779295	[539]	[199,226,NaN]	0	hSpCas9	negative selection	9829715
12604220	12604243	3	+	27869803	PATU8988S	viability after 35 days	GGAACCTTCAGATGAGGGACTGG	RAF1	ENSG00000132155	-0.5352970158986583	[431]	[143,95,NaN]	-5	hSpCas9	negative selection	9829718
12608851	12608874	3	+	27869803	PATU8988S	viability after 35 days	GACATCGAAATCCATTGAGCAGG	RAF1	ENSG00000132155	-1.1039427752312478	[266]	[62,36,NaN]	-8	hSpCas9	negative selection	9829719
12618599	12618622	3	-	27869803	PATU8988S	viability after 35 days	AGCAGTTTGGCTATCAGCGCCGG	RAF1	ENSG00000132155	-0.8613514081167901	[799]	[111,242,NaN]	-7	hSpCas9	negative selection	9829721
12590899	12590922	3	-	27869803	PATU8988S	viability after 31 days	ACCTGGCAATTGTGACCCAGTGG	RAF1	ENSG00000132155	-1.1598556303724152	[270]	[61,30,NaN]	-8	hSpCas9	negative selection	9912157
12600187	12600210	3	-	27869803	PATU8988S	viability after 31 days	CGTGCCAGCACAAAGAGAGCGGG	RAF1	ENSG00000132155	-0.8075094107052532	[966]	[174,277,NaN]	-7	hSpCas9	negative selection	9912161
12603510	12603533	3	-	27869803	PATU8988S	viability after 31 days	CAACCTGAGTGCTTCTCCCAGGG	RAF1	ENSG00000132155	-0.2840742156685032	[539]	[160,196,NaN]	-3	hSpCas9	negative selection	9912164
12604220	12604243	3	+	27869803	PATU8988S	viability after 31 days	GGAACCTTCAGATGAGGGACTGG	RAF1	ENSG00000132155	-0.15669262930789318	[431]	[194,102,NaN]	-2	hSpCas9	negative selection	9912167
12608851	12608874	3	+	27869803	PATU8988S	viability after 31 days	GACATCGAAATCCATTGAGCAGG	RAF1	ENSG00000132155	-0.920578411648467	[266]	[79,25,NaN]	-7	hSpCas9	negative selection	9912168
12618599	12618622	3	-	27869803	PATU8988S	viability after 31 days	AGCAGTTTGGCTATCAGCGCCGG	RAF1	ENSG00000132155	-0.7644542042969588	[799]	[112,282,NaN]	-7	hSpCas9	negative selection	9912170
12590899	12590922	3	-	27869803	HPAFII	viability after 35 days	ACCTGGCAATTGTGACCCAGTGG	RAF1	ENSG00000132155	-4.333202089968543	[95]	[0,3,NaN]	-9	hSpCas9	negative selection	9994606
12600187	12600210	3	-	27869803	HPAFII	viability after 35 days	CGTGCCAGCACAAAGAGAGCGGG	RAF1	ENSG00000132155	-1.2178855458519822	[615]	[31,248,NaN]	-6	hSpCas9	negative selection	9994610
12603510	12603533	3	-	27869803	HPAFII	viability after 35 days	CAACCTGAGTGCTTCTCCCAGGG	RAF1	ENSG00000132155	0.8731694598600751	[160]	[26,286,NaN]	6	hSpCas9	negative selection	9994613
12604220	12604243	3	+	27869803	HPAFII	viability after 35 days	GGAACCTTCAGATGAGGGACTGG	RAF1	ENSG00000132155	0.07234396033300347	[203]	[101,115,NaN]	0	hSpCas9	negative selection	9994616
12608851	12608874	3	+	27869803	HPAFII	viability after 35 days	GACATCGAAATCCATTGAGCAGG	RAF1	ENSG00000132155	-5.544266617952019	[140]	[1,0,NaN]	-9	hSpCas9	negative selection	9994617
12618599	12618622	3	-	27869803	HPAFII	viability after 35 days	AGCAGTTTGGCTATCAGCGCCGG	RAF1	ENSG00000132155	-1.8042131106925372	[355]	[84,13,NaN]	-7	hSpCas9	negative selection	9994619
12590899	12590922	3	-	27869803	HPAFII	viability after 31 days	ACCTGGCAATTGTGACCCAGTGG	RAF1	ENSG00000132155	-3.9354304816129533	[95]	[3,2,NaN]	-9	hSpCas9	negative selection	10077055
12600187	12600210	3	-	27869803	HPAFII	viability after 31 days	CGTGCCAGCACAAAGAGAGCGGG	RAF1	ENSG00000132155	-1.7066619581454545	[615]	[103,107,NaN]	-7	hSpCas9	negative selection	10077059
12603510	12603533	3	-	27869803	HPAFII	viability after 31 days	CAACCTGAGTGCTTCTCCCAGGG	RAF1	ENSG00000132155	0.2452689914235341	[160]	[19,201,NaN]	1	hSpCas9	negative selection	10077062
12604220	12604243	3	+	27869803	HPAFII	viability after 31 days	GGAACCTTCAGATGAGGGACTGG	RAF1	ENSG00000132155	0.2844021798733822	[203]	[137,140,NaN]	2	hSpCas9	negative selection	10077065
12608851	12608874	3	+	27869803	HPAFII	viability after 31 days	GACATCGAAATCCATTGAGCAGG	RAF1	ENSG00000132155	-4.971938796397323	[140]	[2,1,NaN]	-9	hSpCas9	negative selection	10077066
12618599	12618622	3	-	27869803	HPAFII	viability after 31 days	AGCAGTTTGGCTATCAGCGCCGG	RAF1	ENSG00000132155	-1.3685000425663105	[355]	[96,55,NaN]	-7	hSpCas9	negative selection	10077068
12618514	12618537	3	-	28162770	P31FUJ	viability	GCCGAACAAGCAAAGAACAGTGG	RAF1	ENSG00000132155	-3.11544525377622	[235]	[31]	-9	hSpCas9	negative selection	10221873
12618641	12618664	3	+	28162770	P31FUJ	viability	GCAGCTGGAGCCATCAAACACGG	RAF1	ENSG00000132155	-1.4598711129602997	[514]	[219]	-7	hSpCas9	negative selection	10221874
12590891	12590914	3	-	28162770	P31FUJ	viability	ATTGTGACCCAGTGGTGCGAGGG	RAF1	ENSG00000132155	-1.8115861302064102	[232]	[77]	-8	hSpCas9	negative selection	10221875
12618681	12618704	3	-	28162770	P31FUJ	viability	GCTTGGAAGACGATCAGCAATGG	RAF1	ENSG00000132155	-2.2502896311432194	[165]	[40]	-8	hSpCas9	negative selection	10221876
12612002	12612025	3	-	28162770	P31FUJ	viability	TATGAAAGCACTCAAGGTGAGGG	RAF1	ENSG00000132155	-1.243371446124566	[136]	[67]	-7	hSpCas9	negative selection	10221877
12604214	12604237	3	+	28162770	P31FUJ	viability	GGAGAGGGAACCTTCAGATGAGG	RAF1	ENSG00000132155	-0.840112136653335	[552]	[362]	-6	hSpCas9	negative selection	10221878
12604172	12604195	3	+	28162770	P31FUJ	viability	GACCATGTGGACATTAGGTGTGG	RAF1	ENSG00000132155	-1.1508605908782026	[307]	[162]	-7	hSpCas9	negative selection	10221879
12600187	12600210	3	-	28162770	P31FUJ	viability	CGTGCCAGCACAAAGAGAGCGGG	RAF1	ENSG00000132155	-1.6000792864766145	[306]	[118]	-7	hSpCas9	negative selection	10221880
12591718	12591741	3	-	28162770	P31FUJ	viability	CCAGGCCTTCAGGAATGAGGTGG	RAF1	ENSG00000132155	-2.206806995881434	[164]	[41]	-8	hSpCas9	negative selection	10221881
12585244	12585267	3	-	28162770	P31FUJ	viability	GTGATACATGTAGGCCCCAGAGG	RAF1	ENSG00000132155	-2.3468184647060344	[328]	[75]	-8	hSpCas9	negative selection	10221882
12618514	12618537	3	-	28162770	TF1	viability	GCCGAACAAGCAAAGAACAGTGG	RAF1	ENSG00000132155	NaN	[NaN]	[39]	1	hSpCas9	negative selection	10391239
12618641	12618664	3	+	28162770	TF1	viability	GCAGCTGGAGCCATCAAACACGG	RAF1	ENSG00000132155	NaN	[NaN]	[132]	1	hSpCas9	negative selection	10391240
12590891	12590914	3	-	28162770	TF1	viability	ATTGTGACCCAGTGGTGCGAGGG	RAF1	ENSG00000132155	NaN	[NaN]	[8]	1	hSpCas9	negative selection	10391241
12618681	12618704	3	-	28162770	TF1	viability	GCTTGGAAGACGATCAGCAATGG	RAF1	ENSG00000132155	NaN	[NaN]	[182]	1	hSpCas9	negative selection	10391242
12612002	12612025	3	-	28162770	TF1	viability	TATGAAAGCACTCAAGGTGAGGG	RAF1	ENSG00000132155	NaN	[NaN]	[24]	1	hSpCas9	negative selection	10391243
12604214	12604237	3	+	28162770	TF1	viability	GGAGAGGGAACCTTCAGATGAGG	RAF1	ENSG00000132155	NaN	[NaN]	[98]	1	hSpCas9	negative selection	10391244
12604172	12604195	3	+	28162770	TF1	viability	GACCATGTGGACATTAGGTGTGG	RAF1	ENSG00000132155	NaN	[NaN]	[56]	1	hSpCas9	negative selection	10391245
12600187	12600210	3	-	28162770	TF1	viability	CGTGCCAGCACAAAGAGAGCGGG	RAF1	ENSG00000132155	NaN	[NaN]	[114]	1	hSpCas9	negative selection	10391246
12591718	12591741	3	-	28162770	TF1	viability	CCAGGCCTTCAGGAATGAGGTGG	RAF1	ENSG00000132155	NaN	[NaN]	[43]	1	hSpCas9	negative selection	10391247
12585244	12585267	3	-	28162770	TF1	viability	GTGATACATGTAGGCCCCAGAGG	RAF1	ENSG00000132155	NaN	[NaN]	[180]	1	hSpCas9	negative selection	10391248
12618514	12618537	3	-	28162770	SKM1	viability	GCCGAACAAGCAAAGAACAGTGG	RAF1	ENSG00000132155	-6.799281621521922	[62]	[0]	-9	hSpCas9	negative selection	10560605
12618641	12618664	3	+	28162770	SKM1	viability	GCAGCTGGAGCCATCAAACACGG	RAF1	ENSG00000132155	-3.5165886899176604	[122]	[18]	-9	hSpCas9	negative selection	10560606
12590891	12590914	3	-	28162770	SKM1	viability	ATTGTGACCCAGTGGTGCGAGGG	RAF1	ENSG00000132155	-6.088788238716907	[76]	[1]	-9	hSpCas9	negative selection	10560607
12618681	12618704	3	-	28162770	SKM1	viability	GCTTGGAAGACGATCAGCAATGG	RAF1	ENSG00000132155	-3.991926699464318	[35]	[3]	-9	hSpCas9	negative selection	10560608
12612002	12612025	3	-	28162770	SKM1	viability	TATGAAAGCACTCAAGGTGAGGG	RAF1	ENSG00000132155	-6.1074039168842535	[38]	[0]	-9	hSpCas9	negative selection	10560609
12604214	12604237	3	+	28162770	SKM1	viability	GGAGAGGGAACCTTCAGATGAGG	RAF1	ENSG00000132155	-2.536247215688128	[209]	[63]	-9	hSpCas9	negative selection	10560610
12604172	12604195	3	+	28162770	SKM1	viability	GACCATGTGGACATTAGGTGTGG	RAF1	ENSG00000132155	1.5041633897518278	[67]	[340]	9	hSpCas9	negative selection	10560611
12600187	12600210	3	-	28162770	SKM1	viability	CGTGCCAGCACAAAGAGAGCGGG	RAF1	ENSG00000132155	-3.406964198743162	[53]	[8]	-9	hSpCas9	negative selection	10560612
12591718	12591741	3	-	28162770	SKM1	viability	CCAGGCCTTCAGGAATGAGGTGG	RAF1	ENSG00000132155	-3.6293566200796095	[27]	[3]	-9	hSpCas9	negative selection	10560613
12585244	12585267	3	-	28162770	SKM1	viability	GTGATACATGTAGGCCCCAGAGG	RAF1	ENSG00000132155	-4.366322214245816	[69]	[5]	-9	hSpCas9	negative selection	10560614
12618514	12618537	3	-	28162770	SKM1	viability	GCCGAACAAGCAAAGAACAGTGG	RAF1	ENSG00000132155	-6.799281621521922	[62]	[0]	-9	hSpCas9	negative selection	10729971
12618641	12618664	3	+	28162770	SKM1	viability	GCAGCTGGAGCCATCAAACACGG	RAF1	ENSG00000132155	-3.5165886899176604	[122]	[18]	-9	hSpCas9	negative selection	10729972
12590891	12590914	3	-	28162770	SKM1	viability	ATTGTGACCCAGTGGTGCGAGGG	RAF1	ENSG00000132155	-6.088788238716907	[76]	[1]	-9	hSpCas9	negative selection	10729973
12618681	12618704	3	-	28162770	SKM1	viability	GCTTGGAAGACGATCAGCAATGG	RAF1	ENSG00000132155	-3.991926699464318	[35]	[3]	-9	hSpCas9	negative selection	10729974
12612002	12612025	3	-	28162770	SKM1	viability	TATGAAAGCACTCAAGGTGAGGG	RAF1	ENSG00000132155	-6.1074039168842535	[38]	[0]	-9	hSpCas9	negative selection	10729975
12604214	12604237	3	+	28162770	SKM1	viability	GGAGAGGGAACCTTCAGATGAGG	RAF1	ENSG00000132155	-2.536247215688128	[209]	[63]	-9	hSpCas9	negative selection	10729976
12604172	12604195	3	+	28162770	SKM1	viability	GACCATGTGGACATTAGGTGTGG	RAF1	ENSG00000132155	1.5041633897518278	[67]	[340]	9	hSpCas9	negative selection	10729977
12600187	12600210	3	-	28162770	SKM1	viability	CGTGCCAGCACAAAGAGAGCGGG	RAF1	ENSG00000132155	-3.406964198743162	[53]	[8]	-9	hSpCas9	negative selection	10729978
12591718	12591741	3	-	28162770	SKM1	viability	CCAGGCCTTCAGGAATGAGGTGG	RAF1	ENSG00000132155	-3.6293566200796095	[27]	[3]	-9	hSpCas9	negative selection	10729979
12585244	12585267	3	-	28162770	SKM1	viability	GTGATACATGTAGGCCCCAGAGG	RAF1	ENSG00000132155	-4.366322214245816	[69]	[5]	-9	hSpCas9	negative selection	10729980
12618514	12618537	3	-	28162770	PL21	viability	GCCGAACAAGCAAAGAACAGTGG	RAF1	ENSG00000132155	-4.097540934151365	[235]	[5]	-9	hSpCas9	negative selection	10899337
12618641	12618664	3	+	28162770	PL21	viability	GCAGCTGGAGCCATCAAACACGG	RAF1	ENSG00000132155	-2.86163658309737	[333]	[19]	-9	hSpCas9	negative selection	10899338
12590891	12590914	3	-	28162770	PL21	viability	ATTGTGACCCAGTGGTGCGAGGG	RAF1	ENSG00000132155	-1.2027084757816096	[274]	[51]	-7	hSpCas9	negative selection	10899339
12618681	12618704	3	-	28162770	PL21	viability	GCTTGGAAGACGATCAGCAATGG	RAF1	ENSG00000132155	-1.8136661850357103	[104]	[12]	-8	hSpCas9	negative selection	10899340
12612002	12612025	3	-	28162770	PL21	viability	TATGAAAGCACTCAAGGTGAGGG	RAF1	ENSG00000132155	-2	[192]	[20]	-8	hSpCas9	negative selection	10899341
12604214	12604237	3	+	28162770	PL21	viability	GGAGAGGGAACCTTCAGATGAGG	RAF1	ENSG00000132155	-0.9921714676092667	[616]	[134]	-6	hSpCas9	negative selection	10899342
12604172	12604195	3	+	28162770	PL21	viability	GACCATGTGGACATTAGGTGTGG	RAF1	ENSG00000132155	0.7803328710626044	[201]	[150]	6	hSpCas9	negative selection	10899343
12600187	12600210	3	-	28162770	PL21	viability	CGTGCCAGCACAAAGAGAGCGGG	RAF1	ENSG00000132155	-4.143268207808494	[202]	[4]	-9	hSpCas9	negative selection	10899344
12591718	12591741	3	-	28162770	PL21	viability	CCAGGCCTTCAGGAATGAGGTGG	RAF1	ENSG00000132155	-1.8751485128149168	[117]	[13]	-8	hSpCas9	negative selection	10899345
12585244	12585267	3	-	28162770	PL21	viability	GTGATACATGTAGGCCCCAGAGG	RAF1	ENSG00000132155	-4.031424452745378	[262]	[6]	-9	hSpCas9	negative selection	10899346
12618514	12618537	3	-	28162770	P31FUJ	viability	GCCGAACAAGCAAAGAACAGTGG	RAF1	ENSG00000132155	-3.11544525377622	[235]	[31]	-9	hSpCas9	negative selection	11068703
12618641	12618664	3	+	28162770	P31FUJ	viability	GCAGCTGGAGCCATCAAACACGG	RAF1	ENSG00000132155	-1.4598711129602997	[514]	[219]	-7	hSpCas9	negative selection	11068704
12590891	12590914	3	-	28162770	P31FUJ	viability	ATTGTGACCCAGTGGTGCGAGGG	RAF1	ENSG00000132155	-1.8115861302064102	[232]	[77]	-8	hSpCas9	negative selection	11068705
12618681	12618704	3	-	28162770	P31FUJ	viability	GCTTGGAAGACGATCAGCAATGG	RAF1	ENSG00000132155	-2.2502896311432194	[165]	[40]	-8	hSpCas9	negative selection	11068706
12612002	12612025	3	-	28162770	P31FUJ	viability	TATGAAAGCACTCAAGGTGAGGG	RAF1	ENSG00000132155	-1.243371446124566	[136]	[67]	-7	hSpCas9	negative selection	11068707
12604214	12604237	3	+	28162770	P31FUJ	viability	GGAGAGGGAACCTTCAGATGAGG	RAF1	ENSG00000132155	-0.840112136653335	[552]	[362]	-6	hSpCas9	negative selection	11068708
12604172	12604195	3	+	28162770	P31FUJ	viability	GACCATGTGGACATTAGGTGTGG	RAF1	ENSG00000132155	-1.1508605908782026	[307]	[162]	-7	hSpCas9	negative selection	11068709
12600187	12600210	3	-	28162770	P31FUJ	viability	CGTGCCAGCACAAAGAGAGCGGG	RAF1	ENSG00000132155	-1.6000792864766145	[306]	[118]	-7	hSpCas9	negative selection	11068710
12591718	12591741	3	-	28162770	P31FUJ	viability	CCAGGCCTTCAGGAATGAGGTGG	RAF1	ENSG00000132155	-2.206806995881434	[164]	[41]	-8	hSpCas9	negative selection	11068711
12585244	12585267	3	-	28162770	P31FUJ	viability	GTGATACATGTAGGCCCCAGAGG	RAF1	ENSG00000132155	-2.3468184647060344	[328]	[75]	-8	hSpCas9	negative selection	11068712
12618514	12618537	3	-	28162770	OCIAML5	viability	GCCGAACAAGCAAAGAACAGTGG	RAF1	ENSG00000132155	-2.154629340884428	[110]	[44]	-8	hSpCas9	negative selection	11238069
12618641	12618664	3	+	28162770	OCIAML5	viability	GCAGCTGGAGCCATCAAACACGG	RAF1	ENSG00000132155	-1.5009563983747036	[322]	[205]	-7	hSpCas9	negative selection	11238070
12590891	12590914	3	-	28162770	OCIAML5	viability	ATTGTGACCCAGTGGTGCGAGGG	RAF1	ENSG00000132155	-1.8357647585348966	[175]	[88]	-7	hSpCas9	negative selection	11238071
12618681	12618704	3	-	28162770	OCIAML5	viability	GCTTGGAAGACGATCAGCAATGG	RAF1	ENSG00000132155	-1.5807645490466027	[115]	[69]	-7	hSpCas9	negative selection	11238072
12612002	12612025	3	-	28162770	OCIAML5	viability	TATGAAAGCACTCAAGGTGAGGG	RAF1	ENSG00000132155	-0.48097241917275	[74]	[96]	-3	hSpCas9	negative selection	11238073
12604214	12604237	3	+	28162770	OCIAML5	viability	GGAGAGGGAACCTTCAGATGAGG	RAF1	ENSG00000132155	-1.1844701094099217	[310]	[246]	-6	hSpCas9	negative selection	11238074
12604172	12604195	3	+	28162770	OCIAML5	viability	GACCATGTGGACATTAGGTGTGG	RAF1	ENSG00000132155	0.37741527525877017	[144]	[339]	3	hSpCas9	negative selection	11238075
12600187	12600210	3	-	28162770	OCIAML5	viability	CGTGCCAGCACAAAGAGAGCGGG	RAF1	ENSG00000132155	-1.071379599268473	[155]	[133]	-6	hSpCas9	negative selection	11238076
12591718	12591741	3	-	28162770	OCIAML5	viability	CCAGGCCTTCAGGAATGAGGTGG	RAF1	ENSG00000132155	-2.318384575086534	[104]	[37]	-8	hSpCas9	negative selection	11238077
12585244	12585267	3	-	28162770	OCIAML5	viability	GTGATACATGTAGGCCCCAGAGG	RAF1	ENSG00000132155	-1.1788768871311055	[147]	[117]	-6	hSpCas9	negative selection	11238078
12618514	12618537	3	-	28162770	EOL1	viability	GCCGAACAAGCAAAGAACAGTGG	RAF1	ENSG00000132155	-1.648031004694789	[463]	[77]	-8	hSpCas9	negative selection	11407435
12618641	12618664	3	+	28162770	EOL1	viability	GCAGCTGGAGCCATCAAACACGG	RAF1	ENSG00000132155	-0.19715065014644018	[580]	[266]	-1	hSpCas9	negative selection	11407436
12590891	12590914	3	-	28162770	EOL1	viability	ATTGTGACCCAGTGGTGCGAGGG	RAF1	ENSG00000132155	-1.2685668572436675	[438]	[95]	-7	hSpCas9	negative selection	11407437
12618681	12618704	3	-	28162770	EOL1	viability	GCTTGGAAGACGATCAGCAATGG	RAF1	ENSG00000132155	0.13670100840214416	[201]	[116]	1	hSpCas9	negative selection	11407438
12612002	12612025	3	-	28162770	EOL1	viability	TATGAAAGCACTCAAGGTGAGGG	RAF1	ENSG00000132155	-0.1143712177217677	[262]	[127]	-1	hSpCas9	negative selection	11407439
12604214	12604237	3	+	28162770	EOL1	viability	GGAGAGGGAACCTTCAGATGAGG	RAF1	ENSG00000132155	-1.2403195733654113	[1138]	[253]	-7	hSpCas9	negative selection	11407440
12604172	12604195	3	+	28162770	EOL1	viability	GACCATGTGGACATTAGGTGTGG	RAF1	ENSG00000132155	-0.7425158093655153	[234]	[73]	-5	hSpCas9	negative selection	11407441
12600187	12600210	3	-	28162770	EOL1	viability	CGTGCCAGCACAAAGAGAGCGGG	RAF1	ENSG00000132155	0.027447679154825516	[256]	[137]	0	hSpCas9	negative selection	11407442
12591718	12591741	3	-	28162770	EOL1	viability	CCAGGCCTTCAGGAATGAGGTGG	RAF1	ENSG00000132155	-0.36273418050993644	[143]	[58]	-3	hSpCas9	negative selection	11407443
12585244	12585267	3	-	28162770	EOL1	viability	GTGATACATGTAGGCCCCAGAGG	RAF1	ENSG00000132155	-0.7009425357332322	[360]	[116]	-5	hSpCas9	negative selection	11407444
12618514	12618537	3	-	28162770	MOLM13	viability	GCCGAACAAGCAAAGAACAGTGG	RAF1	ENSG00000132155	-0.011918373124502835	[409]	[293]	0	hSpCas9	negative selection	11576801
12618641	12618664	3	+	28162770	MOLM13	viability	GCAGCTGGAGCCATCAAACACGG	RAF1	ENSG00000132155	0.5542736874441883	[550]	[584]	4	hSpCas9	negative selection	11576802
12590891	12590914	3	-	28162770	MOLM13	viability	ATTGTGACCCAGTGGTGCGAGGG	RAF1	ENSG00000132155	1.5636949682955785	[283]	[606]	9	hSpCas9	negative selection	11576803
12618681	12618704	3	-	28162770	MOLM13	viability	GCTTGGAAGACGATCAGCAATGG	RAF1	ENSG00000132155	0.2850253243947684	[209]	[184]	2	hSpCas9	negative selection	11576804
12612002	12612025	3	-	28162770	MOLM13	viability	TATGAAAGCACTCAAGGTGAGGG	RAF1	ENSG00000132155	1.4551032265887356	[169]	[336]	9	hSpCas9	negative selection	11576805
12604214	12604237	3	+	28162770	MOLM13	viability	GGAGAGGGAACCTTCAGATGAGG	RAF1	ENSG00000132155	-1.181342840688077	[940]	[299]	-6	hSpCas9	negative selection	11576806
12604172	12604195	3	+	28162770	MOLM13	viability	GACCATGTGGACATTAGGTGTGG	RAF1	ENSG00000132155	-0.6467137400952773	[274]	[126]	-4	hSpCas9	negative selection	11576807
12600187	12600210	3	-	28162770	MOLM13	viability	CGTGCCAGCACAAAGAGAGCGGG	RAF1	ENSG00000132155	-0.2508469713783293	[366]	[222]	-1	hSpCas9	negative selection	11576808
12591718	12591741	3	-	28162770	MOLM13	viability	CCAGGCCTTCAGGAATGAGGTGG	RAF1	ENSG00000132155	-0.3815509418800397	[199]	[110]	-2	hSpCas9	negative selection	11576809
12585244	12585267	3	-	28162770	MOLM13	viability	GTGATACATGTAGGCCCCAGAGG	RAF1	ENSG00000132155	-0.987562386180173	[361]	[131]	-5	hSpCas9	negative selection	11576810
12618514	12618537	3	-	28162770	HEL	viability	GCCGAACAAGCAAAGAACAGTGG	RAF1	ENSG00000132155	-0.15444428499995602	[317]	[182]	-1	hSpCas9	negative selection	11746167
12618641	12618664	3	+	28162770	HEL	viability	GCAGCTGGAGCCATCAAACACGG	RAF1	ENSG00000132155	-0.4381811633832104	[439]	[207]	-3	hSpCas9	negative selection	11746168
12590891	12590914	3	-	28162770	HEL	viability	ATTGTGACCCAGTGGTGCGAGGG	RAF1	ENSG00000132155	0.01383298369160374	[299]	[193]	0	hSpCas9	negative selection	11746169
12618681	12618704	3	-	28162770	HEL	viability	GCTTGGAAGACGATCAGCAATGG	RAF1	ENSG00000132155	0.6634973921671542	[206]	[209]	5	hSpCas9	negative selection	11746170
12612002	12612025	3	-	28162770	HEL	viability	TATGAAAGCACTCAAGGTGAGGG	RAF1	ENSG00000132155	0.5742074503295416	[193]	[184]	5	hSpCas9	negative selection	11746171
12604214	12604237	3	+	28162770	HEL	viability	GGAGAGGGAACCTTCAGATGAGG	RAF1	ENSG00000132155	0.08421389120850331	[756]	[513]	0	hSpCas9	negative selection	11746172
12604172	12604195	3	+	28162770	HEL	viability	GACCATGTGGACATTAGGTGTGG	RAF1	ENSG00000132155	-0.27272765778797525	[231]	[122]	-2	hSpCas9	negative selection	11746173
12600187	12600210	3	-	28162770	HEL	viability	CGTGCCAGCACAAAGAGAGCGGG	RAF1	ENSG00000132155	-0.6190682704494346	[234]	[97]	-4	hSpCas9	negative selection	11746174
12591718	12591741	3	-	28162770	HEL	viability	CCAGGCCTTCAGGAATGAGGTGG	RAF1	ENSG00000132155	-0.3973386073749783	[145]	[70]	-3	hSpCas9	negative selection	11746175
12585244	12585267	3	-	28162770	HEL	viability	GTGATACATGTAGGCCCCAGAGG	RAF1	ENSG00000132155	-0.29796398431587096	[285]	[148]	-2	hSpCas9	negative selection	11746176
12618514	12618537	3	-	28162770	MV411	viability	GCCGAACAAGCAAAGAACAGTGG	RAF1	ENSG00000132155	-0.5260539194085447	[199]	[116]	-4	hSpCas9	negative selection	11915533
12618641	12618664	3	+	28162770	MV411	viability	GCAGCTGGAGCCATCAAACACGG	RAF1	ENSG00000132155	-0.4739311883324123	[459]	[278]	-3	hSpCas9	negative selection	11915534
12590891	12590914	3	-	28162770	MV411	viability	ATTGTGACCCAGTGGTGCGAGGG	RAF1	ENSG00000132155	-1.7150877437985619	[303]	[77]	-8	hSpCas9	negative selection	11915535
12618681	12618704	3	-	28162770	MV411	viability	GCTTGGAAGACGATCAGCAATGG	RAF1	ENSG00000132155	-1.600559355772175	[143]	[39]	-7	hSpCas9	negative selection	11915536
12612002	12612025	3	-	28162770	MV411	viability	TATGAAAGCACTCAAGGTGAGGG	RAF1	ENSG00000132155	-0.3642918595011662	[135]	[88]	-3	hSpCas9	negative selection	11915537
12604214	12604237	3	+	28162770	MV411	viability	GGAGAGGGAACCTTCAGATGAGG	RAF1	ENSG00000132155	-1.0440252633775358	[491]	[200]	-6	hSpCas9	negative selection	11915538
12604172	12604195	3	+	28162770	MV411	viability	GACCATGTGGACATTAGGTGTGG	RAF1	ENSG00000132155	-0.8004969262809268	[152]	[73]	-5	hSpCas9	negative selection	11915539
12600187	12600210	3	-	28162770	MV411	viability	CGTGCCAGCACAAAGAGAGCGGG	RAF1	ENSG00000132155	-0.3826128394669189	[194]	[125]	-3	hSpCas9	negative selection	11915540
12591718	12591741	3	-	28162770	MV411	viability	CCAGGCCTTCAGGAATGAGGTGG	RAF1	ENSG00000132155	-0.4588312461605144	[92]	[56]	-3	hSpCas9	negative selection	11915541
12585244	12585267	3	-	28162770	MV411	viability	GTGATACATGTAGGCCCCAGAGG	RAF1	ENSG00000132155	-0.6978853565969104	[232]	[120]	-5	hSpCas9	negative selection	11915542
12618514	12618537	3	-	28162770	MONOMAC1	viability	GCCGAACAAGCAAAGAACAGTGG	RAF1	ENSG00000132155	-0.9998044996215059	[156]	[89]	-7	hSpCas9	negative selection	12084899
12618641	12618664	3	+	28162770	MONOMAC1	viability	GCAGCTGGAGCCATCAAACACGG	RAF1	ENSG00000132155	-0.3125140644794895	[259]	[239]	-3	hSpCas9	negative selection	12084900
12590891	12590914	3	-	28162770	MONOMAC1	viability	ATTGTGACCCAGTGGTGCGAGGG	RAF1	ENSG00000132155	-0.3896819250019496	[167]	[146]	-3	hSpCas9	negative selection	12084901
12618681	12618704	3	-	28162770	MONOMAC1	viability	GCTTGGAAGACGATCAGCAATGG	RAF1	ENSG00000132155	-1.7484467880696832	[84]	[28]	-8	hSpCas9	negative selection	12084902
12612002	12612025	3	-	28162770	MONOMAC1	viability	TATGAAAGCACTCAAGGTGAGGG	RAF1	ENSG00000132155	-0.8630359198716164	[118]	[74]	-6	hSpCas9	negative selection	12084903
12604214	12604237	3	+	28162770	MONOMAC1	viability	GGAGAGGGAACCTTCAGATGAGG	RAF1	ENSG00000132155	-0.6133047899446582	[390]	[292]	-5	hSpCas9	negative selection	12084904
12604172	12604195	3	+	28162770	MONOMAC1	viability	GACCATGTGGACATTAGGTGTGG	RAF1	ENSG00000132155	0.6298984439675669	[114]	[203]	6	hSpCas9	negative selection	12084905
12600187	12600210	3	-	28162770	MONOMAC1	viability	CGTGCCAGCACAAAGAGAGCGGG	RAF1	ENSG00000132155	-0.3307152822915229	[112]	[102]	-3	hSpCas9	negative selection	12084906
12591718	12591741	3	-	28162770	MONOMAC1	viability	CCAGGCCTTCAGGAATGAGGTGG	RAF1	ENSG00000132155	-1.9684124720115912	[98]	[28]	-8	hSpCas9	negative selection	12084907
12585244	12585267	3	-	28162770	MONOMAC1	viability	GTGATACATGTAGGCCCCAGAGG	RAF1	ENSG00000132155	-0.5872709553378248	[172]	[131]	-5	hSpCas9	negative selection	12084908
12618514	12618537	3	-	28162770	OCIAML2	viability	GCCGAACAAGCAAAGAACAGTGG	RAF1	ENSG00000132155	-0.15819317933209665	[60]	[302]	-1	hSpCas9	negative selection	12254265
12618641	12618664	3	+	28162770	OCIAML2	viability	GCAGCTGGAGCCATCAAACACGG	RAF1	ENSG00000132155	0.6168330160081783	[71]	[611]	6	hSpCas9	negative selection	12254266
12590891	12590914	3	-	28162770	OCIAML2	viability	ATTGTGACCCAGTGGTGCGAGGG	RAF1	ENSG00000132155	-3.220651572233814	[36]	[21]	-9	hSpCas9	negative selection	12254267
12618681	12618704	3	-	28162770	OCIAML2	viability	GCTTGGAAGACGATCAGCAATGG	RAF1	ENSG00000132155	0.4679696300936954	[23]	[183]	4	hSpCas9	negative selection	12254268
12612002	12612025	3	-	28162770	OCIAML2	viability	TATGAAAGCACTCAAGGTGAGGG	RAF1	ENSG00000132155	0.529370174757839	[35]	[287]	5	hSpCas9	negative selection	12254269
12604214	12604237	3	+	28162770	OCIAML2	viability	GGAGAGGGAACCTTCAGATGAGG	RAF1	ENSG00000132155	-3.2432193291390887	[122]	[71]	-9	hSpCas9	negative selection	12254270
12604172	12604195	3	+	28162770	OCIAML2	viability	GACCATGTGGACATTAGGTGTGG	RAF1	ENSG00000132155	-3.693022246578609	[41]	[17]	-9	hSpCas9	negative selection	12254271
12600187	12600210	3	-	28162770	OCIAML2	viability	CGTGCCAGCACAAAGAGAGCGGG	RAF1	ENSG00000132155	-1.371094151691247	[20]	[44]	-7	hSpCas9	negative selection	12254272
12591718	12591741	3	-	28162770	OCIAML2	viability	CCAGGCCTTCAGGAATGAGGTGG	RAF1	ENSG00000132155	-6.5580926664925006	[16]	[0]	-9	hSpCas9	negative selection	12254273
12585244	12585267	3	-	28162770	OCIAML2	viability	GTGATACATGTAGGCCCCAGAGG	RAF1	ENSG00000132155	-4.127742111719153	[40]	[12]	-9	hSpCas9	negative selection	12254274
12618514	12618537	3	-	28162770	OCIAML3	viability	GCCGAACAAGCAAAGAACAGTGG	RAF1	ENSG00000132155	-5.841935153767749	[56]	[2]	-9	hSpCas9	negative selection	12423631
12618641	12618664	3	+	28162770	OCIAML3	viability	GCAGCTGGAGCCATCAAACACGG	RAF1	ENSG00000132155	-1.7653760586361444	[124]	[110]	-8	hSpCas9	negative selection	12423632
12590891	12590914	3	-	28162770	OCIAML3	viability	ATTGTGACCCAGTGGTGCGAGGG	RAF1	ENSG00000132155	-2.2488721542754755	[73]	[46]	-8	hSpCas9	negative selection	12423633
12618681	12618704	3	-	28162770	OCIAML3	viability	GCTTGGAAGACGATCAGCAATGG	RAF1	ENSG00000132155	-1.049687124100353	[23]	[34]	-6	hSpCas9	negative selection	12423634
12612002	12612025	3	-	28162770	OCIAML3	viability	TATGAAAGCACTCAAGGTGAGGG	RAF1	ENSG00000132155	-1.405562550911053	[42]	[48]	-7	hSpCas9	negative selection	12423635
12604214	12604237	3	+	28162770	OCIAML3	viability	GGAGAGGGAACCTTCAGATGAGG	RAF1	ENSG00000132155	-1.3804121672248741	[187]	[217]	-7	hSpCas9	negative selection	12423636
12604172	12604195	3	+	28162770	OCIAML3	viability	GACCATGTGGACATTAGGTGTGG	RAF1	ENSG00000132155	-1.0965079808533464	[67]	[95]	-7	hSpCas9	negative selection	12423637
12600187	12600210	3	-	28162770	OCIAML3	viability	CGTGCCAGCACAAAGAGAGCGGG	RAF1	ENSG00000132155	-1.8055117455178749	[65]	[56]	-8	hSpCas9	negative selection	12423638
12591718	12591741	3	-	28162770	OCIAML3	viability	CCAGGCCTTCAGGAATGAGGTGG	RAF1	ENSG00000132155	-3.6296315500548846	[40]	[9]	-9	hSpCas9	negative selection	12423639
12585244	12585267	3	-	28162770	OCIAML3	viability	GTGATACATGTAGGCCCCAGAGG	RAF1	ENSG00000132155	-2.7394380798457267	[72]	[32]	-9	hSpCas9	negative selection	12423640