Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:5906
• Symbol:RAP1A
• Description:RAP1A, member of RAS oncogene family

DataSource: http://genomecrispr.dkfz.de/#!/results/RAP1A

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
111542220	111542243	1	-	26472758	Jiyoye	viability	GTGTTTCCGTCAGTACGCGAAGG	RAP1A	ENSG00000116473	-2.1777871192152833	[5]	[0]	-8	hSpCas9	negative selection	140140
111542220	111542243	1	-	26472758	KBM7	viability	GTGTTTCCGTCAGTACGCGAAGG	RAP1A	ENSG00000116473	-5.384890429415551	[126,56]	[0,0]	-9	hSpCas9	negative selection	331258
111542220	111542243	1	-	26472758	Raji	viability	GTGTTTCCGTCAGTACGCGAAGG	RAP1A	ENSG00000116473	-3.1405439780699864	[37]	[0]	-9	hSpCas9	negative selection	522376
111542220	111542243	1	-	26472758	K562	viability	GTGTTTCCGTCAGTACGCGAAGG	RAP1A	ENSG00000116473	-4.2791432283905655	[22]	[0]	-9	hSpCas9	negative selection	713494
111564150	111564173	1	+	25494202	A375	resistance to PLX-4720 (puromycin)	ATGAAAATCTGGTCATTGTGTGG	RAP1A	ENSG00000116473	1.4520887409224779	[38,18]	[11,22]	5	dCas9-VP64	positive selection	2394046
111564087	111564110	1	-	25494202	A375	resistance to PLX-4720 (puromycin)	TCATGAGTTTTAGGAGCTTAAGG	RAP1A	ENSG00000116473	-0.8188687000701497	[130,56]	[15,6]	-4	dCas9-VP64	positive selection	2394047
111564123	111564146	1	-	25494202	A375	resistance to PLX-4720 (puromycin)	TTATGTGTAAAACTTGAGGCAGG	RAP1A	ENSG00000116473	-0.4189025580790919	[59,118]	[2,25]	-2	dCas9-VP64	positive selection	2394048
111619657	111619680	1	-	25494202	A375	resistance to PLX-4720 (puromycin)	GCGTTCCGGAGTCCGCTTAAAGG	RAP1A	ENSG00000116473	3.3481839878244473	[66,87]	[15,347]	8	dCas9-VP64	positive selection	2431622
111619636	111619659	1	-	25494202	A375	resistance to PLX-4720 (puromycin)	GGAGCCGCGCACACTGGAGCCGG	RAP1A	ENSG00000116473	1.0316242308522194	[75,73]	[10,57]	4	dCas9-VP64	positive selection	2431623
111619586	111619609	1	-	25494202	A375	resistance to PLX-4720 (puromycin)	GGGGAGTTTTAGCTTTGCGTAGG	RAP1A	ENSG00000116473	0.8649697641580636	[68,59]	[42,6]	3	dCas9-VP64	positive selection	2431624
111564150	111564173	1	+	25494202	A375	resistance to PLX-4720 (zeocin)	ATGAAAATCTGGTCATTGTGTGG	RAP1A	ENSG00000116473	-0.41517033722141916	[218,260]	[29,84]	-4	dCas9-VP64	positive selection	2489301
111564087	111564110	1	-	25494202	A375	resistance to PLX-4720 (zeocin)	TCATGAGTTTTAGGAGCTTAAGG	RAP1A	ENSG00000116473	2.367133148151975	[64,197]	[411,40]	9	dCas9-VP64	positive selection	2489302
111564123	111564146	1	-	25494202	A375	resistance to PLX-4720 (zeocin)	TTATGTGTAAAACTTGAGGCAGG	RAP1A	ENSG00000116473	0.08183925504472422	[59,119]	[16,42]	0	dCas9-VP64	positive selection	2489303
111619657	111619680	1	-	25494202	A375	resistance to PLX-4720 (zeocin)	GCGTTCCGGAGTCCGCTTAAAGG	RAP1A	ENSG00000116473	-0.2373418783136169	[42,220]	[34,36]	-2	dCas9-VP64	positive selection	2526877
111619636	111619659	1	-	25494202	A375	resistance to PLX-4720 (zeocin)	GGAGCCGCGCACACTGGAGCCGG	RAP1A	ENSG00000116473	0.3545615000816873	[121,47]	[52,18]	3	dCas9-VP64	positive selection	2526878
111619586	111619609	1	-	25494202	A375	resistance to PLX-4720 (zeocin)	GGGGAGTTTTAGCTTTGCGTAGG	RAP1A	ENSG00000116473	0.40567160596666696	[44,18]	[17,9]	3	dCas9-VP64	positive selection	2526879
111563933	111563956	1	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CCAATGGAAGGGTCTCCAGCAGG	RAP1A	ENSG00000116473	0.23885576682105852	[2]	[2,2]	6	hSpCas9	positive selection	4129095
111563933	111563956	1	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CCAATGGAAGGGTCTCCAGCAGG	RAP1A	ENSG00000116473	1.7308757385784062	[0]	[0,2,0,0]	9	hSpCas9	positive selection	4193117
111619848	111619871	1	+	27661255	K562	viability	GAGCAGGAGCCACGGCCGAGAGG	RAP1A	ENSG00000116473	0.044049075478173494	[1611,1609]	[1545,1139]	1	dCas9-KRAB	negative selection	5506161
111620060	111620083	1	-	27661255	K562	viability	GGCCGCCGCCCCGACACCGATGG	RAP1A	ENSG00000116473	0.030013617881700816	[935,987]	[846,729]	1	dCas9-KRAB	negative selection	5506162
111620261	111620284	1	-	27661255	K562	viability	GGCTTGTGCTATGACACCTCGGG	RAP1A	ENSG00000116473	0.07510888879312005	[1207,1355]	[1217,955]	2	dCas9-KRAB	negative selection	5506163
111620301	111620324	1	-	27661255	K562	viability	GTACGAGGGCACCGTGTCTGGGG	RAP1A	ENSG00000116473	0.1272941013638509	[1478,1643]	[1524,1218]	4	dCas9-KRAB	negative selection	5506164