Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:5908
• Symbol:RAP1B
• Description:RAP1B, member of RAS oncogene family

DataSource: http://genomecrispr.dkfz.de/#!/results/RAP1B

Export (tab separated) Export to Excel

Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
68648760	68648783	12	+	26472758	Jiyoye	viability	AGGCGTTGGAAAGTCTGCTTTGG	RAP1B	ENSG00000127314	0.2282052404605539	[179]	[158]	1	hSpCas9	negative selection	133510
68652030	68652053	12	+	26472758	Jiyoye	viability	AATCTTGGATACTGCAGGAACGG	RAP1B	ENSG00000127314	-0.471518322271993	[341]	[185]	-3	hSpCas9	negative selection	133511
68648737	68648760	12	+	26472758	Jiyoye	viability	AAGCTAGTCGTTCTTGGCTCAGG	RAP1B	ENSG00000127314	0.516673746436388	[278]	[300]	4	hSpCas9	negative selection	133512
68648746	68648769	12	+	26472758	Jiyoye	viability	GTTCTTGGCTCAGGAGGCGTTGG	RAP1B	ENSG00000127314	-0.48590941457761505	[38]	[20]	-3	hSpCas9	negative selection	133513
68656344	68656367	12	+	26472758	Jiyoye	viability	AGATGAAAGAGTTGTAGGGAAGG	RAP1B	ENSG00000127314	-0.2907960810444691	[145]	[89]	-2	hSpCas9	negative selection	133514
68654110	68654133	12	+	26472758	Jiyoye	viability	AGGAGCAATTTACAGCAATGAGG	RAP1B	ENSG00000127314	-0.06895062717237632	[401]	[288]	0	hSpCas9	negative selection	133515
68654176	68654199	12	-	26472758	Jiyoye	viability	AAATGTGGACTGTGCTGTGATGG	RAP1B	ENSG00000127314	-0.9329000600917483	[199]	[78]	-6	hSpCas9	negative selection	133517
68652025	68652048	12	+	26472758	Jiyoye	viability	CTTGAAATCTTGGATACTGCAGG	RAP1B	ENSG00000127314	-0.33502686102647977	[183]	[109]	-2	hSpCas9	negative selection	133518
68656351	68656374	12	+	26472758	Jiyoye	viability	AGAGTTGTAGGGAAGGAACAAGG	RAP1B	ENSG00000127314	-1.3948852408822177	[135]	[38]	-7	hSpCas9	negative selection	133519
68657140	68657163	12	-	26472758	Jiyoye	viability	TTGCGAGCCTTCCCAGGCACTGG	RAP1B	ENSG00000127314	0.6238541516479277	[252]	[293]	4	hSpCas9	negative selection	133520
68648760	68648783	12	+	26472758	KBM7	viability	AGGCGTTGGAAAGTCTGCTTTGG	RAP1B	ENSG00000127314	0.007058347276077459	[1108,693]	[587,265]	0	hSpCas9	negative selection	324628
68652030	68652053	12	+	26472758	KBM7	viability	AATCTTGGATACTGCAGGAACGG	RAP1B	ENSG00000127314	-0.12239519015668154	[1103,973]	[483,415]	-1	hSpCas9	negative selection	324629
68648737	68648760	12	+	26472758	KBM7	viability	AAGCTAGTCGTTCTTGGCTCAGG	RAP1B	ENSG00000127314	0.3254625991943876	[1236,818]	[689,511]	3	hSpCas9	negative selection	324630
68648746	68648769	12	+	26472758	KBM7	viability	GTTCTTGGCTCAGGAGGCGTTGG	RAP1B	ENSG00000127314	0.17314126272826513	[230,181]	[76,136]	1	hSpCas9	negative selection	324631
68656344	68656367	12	+	26472758	KBM7	viability	AGATGAAAGAGTTGTAGGGAAGG	RAP1B	ENSG00000127314	0.17060766183574133	[464,318]	[260,153]	1	hSpCas9	negative selection	324632
68654110	68654133	12	+	26472758	KBM7	viability	AGGAGCAATTTACAGCAATGAGG	RAP1B	ENSG00000127314	0.8633757764608224	[1165,757]	[892,733]	8	hSpCas9	negative selection	324633
68654176	68654199	12	-	26472758	KBM7	viability	AAATGTGGACTGTGCTGTGATGG	RAP1B	ENSG00000127314	0.4660920750643751	[517,566]	[436,282]	5	hSpCas9	negative selection	324635
68652025	68652048	12	+	26472758	KBM7	viability	CTTGAAATCTTGGATACTGCAGG	RAP1B	ENSG00000127314	0.06794851509631761	[869,611]	[407,317]	0	hSpCas9	negative selection	324636
68656351	68656374	12	+	26472758	KBM7	viability	AGAGTTGTAGGGAAGGAACAAGG	RAP1B	ENSG00000127314	0.24997447991324373	[302,418]	[259,157]	2	hSpCas9	negative selection	324637
68657140	68657163	12	-	26472758	KBM7	viability	TTGCGAGCCTTCCCAGGCACTGG	RAP1B	ENSG00000127314	-0.21502826942899	[1323,1395]	[647,471]	-2	hSpCas9	negative selection	324638
68648760	68648783	12	+	26472758	Raji	viability	AGGCGTTGGAAAGTCTGCTTTGG	RAP1B	ENSG00000127314	0.03487103558923155	[407]	[96]	0	hSpCas9	negative selection	515746
68652030	68652053	12	+	26472758	Raji	viability	AATCTTGGATACTGCAGGAACGG	RAP1B	ENSG00000127314	-0.3600093689663808	[635]	[114]	-3	hSpCas9	negative selection	515747
68648737	68648760	12	+	26472758	Raji	viability	AAGCTAGTCGTTCTTGGCTCAGG	RAP1B	ENSG00000127314	0.6720736410684945	[429]	[158]	6	hSpCas9	negative selection	515748
68648746	68648769	12	+	26472758	Raji	viability	GTTCTTGGCTCAGGAGGCGTTGG	RAP1B	ENSG00000127314	-0.18212308182138548	[43]	[8]	-1	hSpCas9	negative selection	515749
68656344	68656367	12	+	26472758	Raji	viability	AGATGAAAGAGTTGTAGGGAAGG	RAP1B	ENSG00000127314	-1.9877736976667404	[187]	[10]	-8	hSpCas9	negative selection	515750
68654110	68654133	12	+	26472758	Raji	viability	AGGAGCAATTTACAGCAATGAGG	RAP1B	ENSG00000127314	0.3834107796523536	[478]	[144]	3	hSpCas9	negative selection	515751
68654176	68654199	12	-	26472758	Raji	viability	AAATGTGGACTGTGCTGTGATGG	RAP1B	ENSG00000127314	-0.45503639669646834	[253]	[42]	-4	hSpCas9	negative selection	515753
68652025	68652048	12	+	26472758	Raji	viability	CTTGAAATCTTGGATACTGCAGG	RAP1B	ENSG00000127314	-0.13859570628046425	[369]	[77]	-1	hSpCas9	negative selection	515754
68656351	68656374	12	+	26472758	Raji	viability	AGAGTTGTAGGGAAGGAACAAGG	RAP1B	ENSG00000127314	-0.10674126997924804	[115]	[24]	-1	hSpCas9	negative selection	515755
68657140	68657163	12	-	26472758	Raji	viability	TTGCGAGCCTTCCCAGGCACTGG	RAP1B	ENSG00000127314	-0.781732358506943	[725]	[97]	-5	hSpCas9	negative selection	515756
68648760	68648783	12	+	26472758	K562	viability	AGGCGTTGGAAAGTCTGCTTTGG	RAP1B	ENSG00000127314	1.1538161788855401	[689]	[1295]	8	hSpCas9	negative selection	706864
68652030	68652053	12	+	26472758	K562	viability	AATCTTGGATACTGCAGGAACGG	RAP1B	ENSG00000127314	-0.06881743730242085	[1116]	[898]	0	hSpCas9	negative selection	706865
68648737	68648760	12	+	26472758	K562	viability	AAGCTAGTCGTTCTTGGCTCAGG	RAP1B	ENSG00000127314	0.4904510183558677	[881]	[1045]	4	hSpCas9	negative selection	706866
68648746	68648769	12	+	26472758	K562	viability	GTTCTTGGCTCAGGAGGCGTTGG	RAP1B	ENSG00000127314	-1.9203260346701854	[138]	[30]	-7	hSpCas9	negative selection	706867
68656344	68656367	12	+	26472758	K562	viability	AGATGAAAGAGTTGTAGGGAAGG	RAP1B	ENSG00000127314	-1.8282090724209508	[386]	[91]	-7	hSpCas9	negative selection	706868
68654110	68654133	12	+	26472758	K562	viability	AGGAGCAATTTACAGCAATGAGG	RAP1B	ENSG00000127314	0.7383349582512928	[822]	[1158]	6	hSpCas9	negative selection	706869
68654176	68654199	12	-	26472758	K562	viability	AAATGTGGACTGTGCTGTGATGG	RAP1B	ENSG00000127314	-0.47402677852896136	[644]	[391]	-3	hSpCas9	negative selection	706871
68652025	68652048	12	+	26472758	K562	viability	CTTGAAATCTTGGATACTGCAGG	RAP1B	ENSG00000127314	0.626212934909478	[438]	[571]	5	hSpCas9	negative selection	706872
68656351	68656374	12	+	26472758	K562	viability	AGAGTTGTAGGGAAGGAACAAGG	RAP1B	ENSG00000127314	-2.8267882228259733	[352]	[41]	-8	hSpCas9	negative selection	706873
68657140	68657163	12	-	26472758	K562	viability	TTGCGAGCCTTCCCAGGCACTGG	RAP1B	ENSG00000127314	-0.6486660684170411	[1156]	[622]	-4	hSpCas9	negative selection	706874
68623893	68623916	12	+	25494202	A375	resistance to PLX-4720 (puromycin)	CGCCAGTAGTCCCAGCTACTCAG	RAP1B	ENSG00000127314	1.7407213706869107	[8,18]	[8,10]	6	dCas9-VP64	positive selection	2429271
68623893	68623916	12	+	25494202	A375	resistance to PLX-4720 (zeocin)	CGCCAGTAGTCCCAGCTACTCAG	RAP1B	ENSG00000127314	0.9029000398623505	[85,44]	[24,53]	6	dCas9-VP64	positive selection	2524526
68652031	68652054	12	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	AATCTTGGATACTGCAGGAACGG	RAP1B	ENSG00000127314	0.41507921910138784	[4,4]	[3,6]	8	hSpCas9	positive selection	3015642
68652026	68652049	12	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CTTGAAATCTTGGATACTGCAGG	RAP1B	ENSG00000127314	0.35761252581711295	[2,3]	[4,3]	7	hSpCas9	positive selection	3015643
68650448	68650471	12	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GATAGAAGATTCTTATAGAAAGG	RAP1B	ENSG00000127314	0.1909924370688722	[3,3]	[2,4]	4	hSpCas9	positive selection	3015644
68656309	68656332	12	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TTATTACCAACAAGAATCATTGG	RAP1B	ENSG00000127314	-0.22495785232490081	[3,3]	[3,2]	-3	hSpCas9	positive selection	3015645
68652031	68652054	12	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	AATCTTGGATACTGCAGGAACGG	RAP1B	ENSG00000127314	0.3438831202540614	[4,4]	[4,3]	6	hSpCas9	positive selection	3083500
68652026	68652049	12	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CTTGAAATCTTGGATACTGCAGG	RAP1B	ENSG00000127314	0.4627973375257131	[2,2]	[4,1]	7	hSpCas9	positive selection	3083501
68650448	68650471	12	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GATAGAAGATTCTTATAGAAAGG	RAP1B	ENSG00000127314	0.6868733576931586	[3,3]	[4,4]	9	hSpCas9	positive selection	3083502
68656309	68656332	12	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TTATTACCAACAAGAATCATTGG	RAP1B	ENSG00000127314	0.26065394226196537	[3,3]	[1,4]	4	hSpCas9	positive selection	3083503
68650397	68650420		+	24336571	A375	resistance to PLX after 7 days	CAGACTGTACAATTTGTTCAAGG	RAP1B	ENSG00000127314	-0.22654750906164578	[34,34]	[31,27]	-7	hSpCas9	positive selection	3139730
68650447	68650470		+	24336571	A375	resistance to PLX after 7 days	GATAGAAGATTCTTATAGAAAGG	RAP1B	ENSG00000127314	0.37700469278046134	[3,4]	[5,5]	8	hSpCas9	positive selection	3139731
68656303	68656326		+	24336571	A375	resistance to PLX after 7 days	TAGGTTCCAATGATTCTTGTTGG	RAP1B	ENSG00000127314	-0.054850494891182766	[5,5]	[5,5]	-1	hSpCas9	positive selection	3139732
68650397	68650420		+	24336571	A375	resistance to PLX after 14 days	CAGACTGTACAATTTGTTCAAGG	RAP1B	ENSG00000127314	-0.7410341796399965	[37,37]	[9,9]	-8	hSpCas9	positive selection	3197523
68650447	68650470		+	24336571	A375	resistance to PLX after 14 days	GATAGAAGATTCTTATAGAAAGG	RAP1B	ENSG00000127314	1.1592418156203674	[2,3]	[2,3]	8	hSpCas9	positive selection	3197524
68656303	68656326		+	24336571	A375	resistance to PLX after 14 days	TAGGTTCCAATGATTCTTGTTGG	RAP1B	ENSG00000127314	1.9864142698045895	[6,7]	[11,16]	9	hSpCas9	positive selection	3197525
68650397	68650420		+	24336571	A375	viability after 7 days	CAGACTGTACAATTTGTTCAAGG	RAP1B	ENSG00000127314	0.4030934845929086	[27]	[34,34]	6	hSpCas9	negative selection	3255316
68650447	68650470		+	24336571	A375	viability after 7 days	GATAGAAGATTCTTATAGAAAGG	RAP1B	ENSG00000127314	-1.2157023619181608	[11]	[3,4]	-9	hSpCas9	negative selection	3255317
68656303	68656326		+	24336571	A375	viability after 7 days	TAGGTTCCAATGATTCTTGTTGG	RAP1B	ENSG00000127314	-0.4178240903764562	[8]	[5,5]	-5	hSpCas9	negative selection	3255318
68650397	68650420		+	24336571	A375	viability after 14 days	CAGACTGTACAATTTGTTCAAGG	RAP1B	ENSG00000127314	0.5170885719012461	[27]	[37,37]	6	hSpCas9	negative selection	3313109
68650447	68650470		+	24336571	A375	viability after 14 days	GATAGAAGATTCTTATAGAAAGG	RAP1B	ENSG00000127314	-1.6401123451271815	[11]	[2,3]	-9	hSpCas9	negative selection	3313110
68656303	68656326		+	24336571	A375	viability after 14 days	TAGGTTCCAATGATTCTTGTTGG	RAP1B	ENSG00000127314	-0.1576518953742515	[8]	[6,7]	-2	hSpCas9	negative selection	3313111
68656428	68656451	12	+	27383988	293T	resistance to West Nile virus (flavivirus)	ATCAAAAATAAATGTTAATGAGG	RAP1B	ENSG00000127314	0.15929412848530838	[136,136]	[0,0]	0	hSpCas9	positive selection	3388965
68652015	68652038	12	+	27383988	293T	resistance to West Nile virus (flavivirus)	ACAGTGTATGCTTGAAATCTTGG	RAP1B	ENSG00000127314	-0.3201026165899134	[190,190]	[0,0]	-2	hSpCas9	positive selection	3388966
68654213	68654236	12	-	27383988	293T	resistance to West Nile virus (flavivirus)	CTCGAAGAATCTGTTCTCTCAGG	RAP1B	ENSG00000127314	-0.2184072195205627	[177,177]	[0,0]	-1	hSpCas9	positive selection	3388967
68652030	68652053	12	+	26780180	HT29	viability (Avana library 4 designs)	AATCTTGGATACTGCAGGAACGG	RAP1B	ENSG00000127314	1.46053978267546	[]	[]	5	hSpCas9	negative selection	3453904
68652025	68652048	12	+	26780180	HT29	viability (Avana library 4 designs)	CTTGAAATCTTGGATACTGCAGG	RAP1B	ENSG00000127314	1.78645772169476	[]	[]	6	hSpCas9	negative selection	3453905
68650447	68650470	12	+	26780180	HT29	viability (Avana library 4 designs)	GATAGAAGATTCTTATAGAAAGG	RAP1B	ENSG00000127314	1.1049570999235	[]	[]	4	hSpCas9	negative selection	3453906
68656309	68656332	12	-	26780180	HT29	viability (Avana library 4 designs)	TTATTACCAACAAGAATCATTGG	RAP1B	ENSG00000127314	1.475562637134	[]	[]	6	hSpCas9	negative selection	3453907
68652030	68652053	12	+	26780180	A375	viability (Avana lentiCRISPRv2)	AATCTTGGATACTGCAGGAACGG	RAP1B	ENSG00000127314	-4.5407787018769	[]	[]	-5	hSpCas9	negative selection	3550993
68650447	68650470	12	+	26780180	A375	viability (Avana lentiCRISPRv2)	GATAGAAGATTCTTATAGAAAGG	RAP1B	ENSG00000127314	-19.7628465710764	[]	[]	-9	hSpCas9	negative selection	3550994
68656309	68656332	12	-	26780180	A375	viability (Avana lentiCRISPRv2)	TTATTACCAACAAGAATCATTGG	RAP1B	ENSG00000127314	-21.0561817390383	[]	[]	-9	hSpCas9	negative selection	3550995
68652025	68652048	12	+	26780180	A375	viability (Avana lentiCRISPRv2)	CTTGAAATCTTGGATACTGCAGG	RAP1B	ENSG00000127314	-1.48769765494827	[]	[]	-2	hSpCas9	negative selection	3550996
68651991	68652014	12	-	26780180	A375	viability (Avana lentiCRISPRv2)	GTGCATCTACTTCAACTTGCTGG	RAP1B	ENSG00000127314	-3.81185441179407	[]	[]	-4	hSpCas9	negative selection	3550997
68652034	68652057	12	+	26780180	A375	viability (Avana lentiCRISPRv2)	TTGGATACTGCAGGAACGGTAGG	RAP1B	ENSG00000127314	-2.54970842988315	[]	[]	-3	hSpCas9	negative selection	3550998
68652030	68652053	12	+	26780180	A375	viability (Avana lentiGuide)	AATCTTGGATACTGCAGGAACGG	RAP1B	ENSG00000127314	8.64060146284305	[]	[]	6	hSpCas9	negative selection	3659652
68650447	68650470	12	+	26780180	A375	viability (Avana lentiGuide)	GATAGAAGATTCTTATAGAAAGG	RAP1B	ENSG00000127314	8.58646289261945	[]	[]	6	hSpCas9	negative selection	3659653
68656309	68656332	12	-	26780180	A375	viability (Avana lentiGuide)	TTATTACCAACAAGAATCATTGG	RAP1B	ENSG00000127314	3.27956726963382	[]	[]	3	hSpCas9	negative selection	3659654
68652025	68652048	12	+	26780180	A375	viability (Avana lentiGuide)	CTTGAAATCTTGGATACTGCAGG	RAP1B	ENSG00000127314	10.6246518953079	[]	[]	7	hSpCas9	negative selection	3659655
68651991	68652014	12	-	26780180	A375	viability (Avana lentiGuide)	GTGCATCTACTTCAACTTGCTGG	RAP1B	ENSG00000127314	-1.7196365577613	[]	[]	-3	hSpCas9	negative selection	3659656
68652034	68652057	12	+	26780180	A375	viability (Avana lentiGuide)	TTGGATACTGCAGGAACGGTAGG	RAP1B	ENSG00000127314	13.7776596242737	[]	[]	7	hSpCas9	negative selection	3659657
68652030	68652053	12	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AATCTTGGATACTGCAGGAACGG	RAP1B	ENSG00000127314	-0.2562658871264879	[6]	[5,5]	-4	hSpCas9	positive selection	3768259
68650447	68650470	12	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GATAGAAGATTCTTATAGAAAGG	RAP1B	ENSG00000127314	-0.7575292942889891	[9]	[5,4]	-8	hSpCas9	positive selection	3768260
68656309	68656332	12	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TTATTACCAACAAGAATCATTGG	RAP1B	ENSG00000127314	-0.9786072224338329	[9]	[5,2]	-8	hSpCas9	positive selection	3768261
68652025	68652048	12	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CTTGAAATCTTGGATACTGCAGG	RAP1B	ENSG00000127314	-0.29655632954847416	[5]	[4,3]	-4	hSpCas9	positive selection	3768262
68651991	68652014	12	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GTGCATCTACTTCAACTTGCTGG	RAP1B	ENSG00000127314	-0.09537674572339103	[5]	[5,3]	-1	hSpCas9	positive selection	3768263
68652034	68652057	12	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TTGGATACTGCAGGAACGGTAGG	RAP1B	ENSG00000127314	0.11519365553407661	[5]	[5,5]	3	hSpCas9	positive selection	3768264
68652030	68652053	12	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AATCTTGGATACTGCAGGAACGG	RAP1B	ENSG00000127314	-0.4054954073621434	[6]	[2,4]	-5	hSpCas9	positive selection	3876866
68650447	68650470	12	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GATAGAAGATTCTTATAGAAAGG	RAP1B	ENSG00000127314	-0.1414619698556803	[5]	[2,4]	-2	hSpCas9	positive selection	3876867
68656309	68656332	12	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TTATTACCAACAAGAATCATTGG	RAP1B	ENSG00000127314	0.1857470868327469	[5]	[5,5]	4	hSpCas9	positive selection	3876868
68652025	68652048	12	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CTTGAAATCTTGGATACTGCAGG	RAP1B	ENSG00000127314	0.13821886992406326	[5]	[4,5]	3	hSpCas9	positive selection	3876869
68651991	68652014	12	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GTGCATCTACTTCAACTTGCTGG	RAP1B	ENSG00000127314	0.241970894745775	[6]	[7,6]	6	hSpCas9	positive selection	3876870
68652034	68652057	12	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TTGGATACTGCAGGAACGGTAGG	RAP1B	ENSG00000127314	0.04200599620400955	[5]	[3,5]	0	hSpCas9	positive selection	3876871
68652015	68652038	12	+	26780180	A375	viability	ACAGTGTATGCTTGAAATCTTGG	RAP1B	ENSG00000127314	0.861868491184744	[]	[]	3	hSpCas9	negative selection	3987275
68656428	68656451	12	+	26780180	A375	viability	ATCAAAAATAAATGTTAATGAGG	RAP1B	ENSG00000127314	0.718968327671532	[]	[]	2	hSpCas9	negative selection	3987276
68650397	68650420	12	+	26780180	A375	viability	CAGACTGTACAATTTGTTCAAGG	RAP1B	ENSG00000127314	1.33928605617046	[]	[]	7	hSpCas9	negative selection	3987277
68650447	68650470	12	+	26780180	A375	viability	GATAGAAGATTCTTATAGAAAGG	RAP1B	ENSG00000127314	0.376201049558414	[]	[]	0	hSpCas9	negative selection	3987278
68656303	68656326	12	+	26780180	A375	viability	TAGGTTCCAATGATTCTTGTTGG	RAP1B	ENSG00000127314	1.28261970620032	[]	[]	7	hSpCas9	negative selection	3987279
68652015	68652038	12	+	26780180	HT29	viability (GeCKOv2 library)	ACAGTGTATGCTTGAAATCTTGG	RAP1B	ENSG00000127314	0.51670804870347	[]	[]	1	hSpCas9	negative selection	4095241
68656428	68656451	12	+	26780180	HT29	viability (GeCKOv2 library)	ATCAAAAATAAATGTTAATGAGG	RAP1B	ENSG00000127314	0.981829658190268	[]	[]	4	hSpCas9	negative selection	4095242
68650397	68650420	12	+	26780180	HT29	viability (GeCKOv2 library)	CAGACTGTACAATTTGTTCAAGG	RAP1B	ENSG00000127314	1.25052331770255	[]	[]	6	hSpCas9	negative selection	4095243
68650447	68650470	12	+	26780180	HT29	viability (GeCKOv2 library)	GATAGAAGATTCTTATAGAAAGG	RAP1B	ENSG00000127314	0.392925589767475	[]	[]	1	hSpCas9	negative selection	4095244
68656303	68656326	12	+	26780180	HT29	viability (GeCKOv2 library)	TAGGTTCCAATGATTCTTGTTGG	RAP1B	ENSG00000127314	1.82663437232178	[]	[]	8	hSpCas9	negative selection	4095245
68650397	68650420	12	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CAGACTGTACAATTTGTTCAAGG	RAP1B	ENSG00000127314	0.16912540542080312	[4]	[3,3]	4	hSpCas9	positive selection	4165088
68650447	68650470	12	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GATAGAAGATTCTTATAGAAAGG	RAP1B	ENSG00000127314	0.3016197523348384	[2]	[3,1]	7	hSpCas9	positive selection	4165089
68656303	68656326	12	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TAGGTTCCAATGATTCTTGTTGG	RAP1B	ENSG00000127314	0.6581922296000147	[2]	[2,3]	9	hSpCas9	positive selection	4165090
68650397	68650420	12	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CAGACTGTACAATTTGTTCAAGG	RAP1B	ENSG00000127314	1.141499982041632	[4]	[5,4,6,3]	8	hSpCas9	positive selection	4229110
68650447	68650470	12	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GATAGAAGATTCTTATAGAAAGG	RAP1B	ENSG00000127314	1.156758613690954	[2]	[0,0,0,4]	8	hSpCas9	positive selection	4229111
68656303	68656326	12	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TAGGTTCCAATGATTCTTGTTGG	RAP1B	ENSG00000127314	0.6501002436773169	[3]	[3,4,4,0]	4	hSpCas9	positive selection	4229112
68650447	68650470	12	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GATAGAAGATTCTTATAGAAAGG	RAP1B	ENSG00000127314	0.4711351322249334	[0]	[0,0]	8	hSpCas9	positive selection	4293855
68656303	68656326	12	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TAGGTTCCAATGATTCTTGTTGG	RAP1B	ENSG00000127314	-0.13232530574904794	[2]	[1,1]	-3	hSpCas9	positive selection	4293856
68650397	68650420	12	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CAGACTGTACAATTTGTTCAAGG	RAP1B	ENSG00000127314	0.36752715897593957	[3]	[3,2]	7	hSpCas9	positive selection	4293857
68656428	68656451	12	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ATCAAAAATAAATGTTAATGAGG	RAP1B	ENSG00000127314	-0.25145915554453435	[2]	[2,0]	-5	hSpCas9	positive selection	4358113
68652015	68652038	12	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ACAGTGTATGCTTGAAATCTTGG	RAP1B	ENSG00000127314	0.2978721081927884	[3]	[3,3]	6	hSpCas9	positive selection	4358114
68650442	68650464	12	-	27760321	OCIAML3	viability	TATAAGAATCTTCTATCGTAGG	RAP1B	ENSG00000127314	-3.158212929956358	[12,9]	[0,0]	-9	hSpCas9	negative selection	4433111
68651991	68652013	12	-	27760321	OCIAML3	viability	TGCATCTACTTCAACTTGCTGG	RAP1B	ENSG00000127314	-0.6200031068806152	[708,501]	[352,241]	-6	hSpCas9	negative selection	4433112
68652031	68652053	12	+	27760321	OCIAML3	viability	ATCTTGGATACTGCAGGAACGG	RAP1B	ENSG00000127314	-1.1803109737551092	[251,248]	[54,127]	-8	hSpCas9	negative selection	4433113
68656321	68656343	12	+	27760321	OCIAML3	viability	GTTGGTAATAAGTGTGACTTGG	RAP1B	ENSG00000127314	-0.010225747681253505	[175,134]	[131,103]	0	hSpCas9	negative selection	4433114
68656352	68656374	12	+	27760321	OCIAML3	viability	GAGTTGTAGGGAAGGAACAAGG	RAP1B	ENSG00000127314	-2.0720697397711056	[199,179]	[33,36]	-9	hSpCas9	negative selection	4433115
68654137	68654159	12	+	27760321	OCIAML3	viability	TATACATGAAAAATGGACAAGG	RAP1B	ENSG00000127314	-2.2292202716167795	[8,12]	[0,2]	-9	hSpCas9	negative selection	4433116
68654176	68654198	12	-	27760321	OCIAML3	viability	AATGTGGACTGTGCTGTGATGG	RAP1B	ENSG00000127314	-0.0678237387436551	[709,631]	[403,624]	0	hSpCas9	negative selection	4433117
68654191	68654213	12	-	27760321	OCIAML3	viability	TCTTGTAAATCGTTAAATGTGG	RAP1B	ENSG00000127314	-1.0439209590791831	[30,32]	[6,18]	-7	hSpCas9	negative selection	4433118
68654213	68654235	12	-	27760321	OCIAML3	viability	TCGAAGAATCTGTTCTCTCAGG	RAP1B	ENSG00000127314	-1.5953592307440503	[220,178]	[57,42]	-8	hSpCas9	negative selection	4433119
68650442	68650464	12	-	27760321	OCIAML2	viability	TATAAGAATCTTCTATCGTAGG	RAP1B	ENSG00000127314	-3.2069582952214066	[12,9]	[0,0]	-9	hSpCas9	negative selection	4516574
68651991	68652013	12	-	27760321	OCIAML2	viability	TGCATCTACTTCAACTTGCTGG	RAP1B	ENSG00000127314	-0.07326762078639637	[708,501]	[356,596]	-1	hSpCas9	negative selection	4516575
68652031	68652053	12	+	27760321	OCIAML2	viability	ATCTTGGATACTGCAGGAACGG	RAP1B	ENSG00000127314	-0.35015467225389196	[251,248]	[139,184]	-4	hSpCas9	negative selection	4516576
68656321	68656343	12	+	27760321	OCIAML2	viability	GTTGGTAATAAGTGTGACTTGG	RAP1B	ENSG00000127314	-0.5349539090860176	[175,134]	[61,117]	-5	hSpCas9	negative selection	4516577
68656352	68656374	12	+	27760321	OCIAML2	viability	GAGTTGTAGGGAAGGAACAAGG	RAP1B	ENSG00000127314	-1.7271490120753759	[199,179]	[32,63]	-9	hSpCas9	negative selection	4516578
68654137	68654159	12	+	27760321	OCIAML2	viability	TATACATGAAAAATGGACAAGG	RAP1B	ENSG00000127314	2.1131406417233496	[8,12]	[30,49]	9	hSpCas9	negative selection	4516579
68654176	68654198	12	-	27760321	OCIAML2	viability	AATGTGGACTGTGCTGTGATGG	RAP1B	ENSG00000127314	-0.04176962417830998	[709,631]	[447,629]	0	hSpCas9	negative selection	4516580
68654191	68654213	12	-	27760321	OCIAML2	viability	TCTTGTAAATCGTTAAATGTGG	RAP1B	ENSG00000127314	-1.1928583366501995	[30,32]	[16,3]	-8	hSpCas9	negative selection	4516581
68654213	68654235	12	-	27760321	OCIAML2	viability	TCGAAGAATCTGTTCTCTCAGG	RAP1B	ENSG00000127314	-0.3298164130294454	[220,178]	[121,135]	-4	hSpCas9	negative selection	4516582
68650442	68650464	12	-	27760321	MV411	viability	TATAAGAATCTTCTATCGTAGG	RAP1B	ENSG00000127314	-2.913134361041676	[12,9]	[0,0]	-9	hSpCas9	negative selection	4600037
68651991	68652013	12	-	27760321	MV411	viability	TGCATCTACTTCAACTTGCTGG	RAP1B	ENSG00000127314	0.1989315458021541	[708,501]	[593,242]	1	hSpCas9	negative selection	4600038
68652031	68652053	12	+	27760321	MV411	viability	ATCTTGGATACTGCAGGAACGG	RAP1B	ENSG00000127314	1.740277336693969	[251,248]	[584,506]	9	hSpCas9	negative selection	4600039
68656321	68656343	12	+	27760321	MV411	viability	GTTGGTAATAAGTGTGACTTGG	RAP1B	ENSG00000127314	1.396965867473437	[175,134]	[262,275]	8	hSpCas9	negative selection	4600040
68656352	68656374	12	+	27760321	MV411	viability	GAGTTGTAGGGAAGGAACAAGG	RAP1B	ENSG00000127314	-1.0153340314103294	[199,179]	[17,127]	-6	hSpCas9	negative selection	4600041
68654137	68654159	12	+	27760321	MV411	viability	TATACATGAAAAATGGACAAGG	RAP1B	ENSG00000127314	-2.8857866307235236	[8,12]	[0,0]	-9	hSpCas9	negative selection	4600042
68654176	68654198	12	-	27760321	MV411	viability	AATGTGGACTGTGCTGTGATGG	RAP1B	ENSG00000127314	0.8619581773931702	[709,631]	[1022,473]	6	hSpCas9	negative selection	4600043
68654191	68654213	12	-	27760321	MV411	viability	TCTTGTAAATCGTTAAATGTGG	RAP1B	ENSG00000127314	-1.3741623515856416	[30,32]	[0,18]	-7	hSpCas9	negative selection	4600044
68654213	68654235	12	-	27760321	MV411	viability	TCGAAGAATCTGTTCTCTCAGG	RAP1B	ENSG00000127314	0.12223961136953587	[220,178]	[2,352]	0	hSpCas9	negative selection	4600045
68650442	68650464	12	-	27760321	HL60	viability	TATAAGAATCTTCTATCGTAGG	RAP1B	ENSG00000127314	-3.2210045228358126	[12,9]	[0,0]	-9	hSpCas9	negative selection	4683500
68651991	68652013	12	-	27760321	HL60	viability	TGCATCTACTTCAACTTGCTGG	RAP1B	ENSG00000127314	0.3519382595152293	[708,501]	[623,624]	4	hSpCas9	negative selection	4683501
68652031	68652053	12	+	27760321	HL60	viability	ATCTTGGATACTGCAGGAACGG	RAP1B	ENSG00000127314	0.04644092503164754	[251,248]	[208,214]	0	hSpCas9	negative selection	4683502
68656321	68656343	12	+	27760321	HL60	viability	GTTGGTAATAAGTGTGACTTGG	RAP1B	ENSG00000127314	-0.2777228981350377	[175,134]	[169,33]	-3	hSpCas9	negative selection	4683503
68656352	68656374	12	+	27760321	HL60	viability	GAGTTGTAGGGAAGGAACAAGG	RAP1B	ENSG00000127314	-0.7006718958114606	[199,179]	[91,98]	-6	hSpCas9	negative selection	4683504
68654137	68654159	12	+	27760321	HL60	viability	TATACATGAAAAATGGACAAGG	RAP1B	ENSG00000127314	1.0983856186136034	[8,12]	[5,33]	9	hSpCas9	negative selection	4683505
68654176	68654198	12	-	27760321	HL60	viability	AATGTGGACTGTGCTGTGATGG	RAP1B	ENSG00000127314	0.11455454295284495	[709,631]	[510,678]	1	hSpCas9	negative selection	4683506
68654191	68654213	12	-	27760321	HL60	viability	TCTTGTAAATCGTTAAATGTGG	RAP1B	ENSG00000127314	-0.732538821958193	[30,32]	[9,21]	-6	hSpCas9	negative selection	4683507
68654213	68654235	12	-	27760321	HL60	viability	TCGAAGAATCTGTTCTCTCAGG	RAP1B	ENSG00000127314	0.8523618986902524	[220,178]	[322,261]	8	hSpCas9	negative selection	4683508
68650442	68650464	12	-	27760321	HT1080	viability	TATAAGAATCTTCTATCGTAGG	RAP1B	ENSG00000127314	-1.8443172389209588	[9,7]	[0,0]	-6	hSpCas9	negative selection	4766963
68651991	68652013	12	-	27760321	HT1080	viability	TGCATCTACTTCAACTTGCTGG	RAP1B	ENSG00000127314	-0.9864083756152238	[501,391]	[118,57]	-4	hSpCas9	negative selection	4766964
68652031	68652053	12	+	27760321	HT1080	viability	ATCTTGGATACTGCAGGAACGG	RAP1B	ENSG00000127314	-2.560013097239588	[248,194]	[14,14]	-7	hSpCas9	negative selection	4766965
68656321	68656343	12	+	27760321	HT1080	viability	GTTGGTAATAAGTGTGACTTGG	RAP1B	ENSG00000127314	-5.585610975063997	[134,105]	[0,0]	-8	hSpCas9	negative selection	4766966
68656352	68656374	12	+	27760321	HT1080	viability	GAGTTGTAGGGAAGGAACAAGG	RAP1B	ENSG00000127314	-1.3907079319477489	[179,140]	[0,49]	-5	hSpCas9	negative selection	4766967
68654137	68654159	12	+	27760321	HT1080	viability	TATACATGAAAAATGGACAAGG	RAP1B	ENSG00000127314	-2.194450976201537	[12,9]	[0,0]	-6	hSpCas9	negative selection	4766968
68654176	68654198	12	-	27760321	HT1080	viability	AATGTGGACTGTGCTGTGATGG	RAP1B	ENSG00000127314	-7.807846426983687	[631,492]	[0,0]	-9	hSpCas9	negative selection	4766969
68654191	68654213	12	-	27760321	HT1080	viability	TCTTGTAAATCGTTAAATGTGG	RAP1B	ENSG00000127314	-3.5556706373749467	[32,25]	[0,0]	-7	hSpCas9	negative selection	4766970
68654213	68654235	12	-	27760321	HT1080	viability	TCGAAGAATCTGTTCTCTCAGG	RAP1B	ENSG00000127314	0.012177038280681174	[178,139]	[86,38]	0	hSpCas9	negative selection	4766971
68650442	68650464	12	-	27760321	HT29	viability after 7 days	TATAAGAATCTTCTATCGTAGG	RAP1B	ENSG00000127314	0.3431737320556998	[9,7]	[10,31,0]	5	hSpCas9	negative selection	4850426
68651991	68652013	12	-	27760321	HT29	viability after 7 days	TGCATCTACTTCAACTTGCTGG	RAP1B	ENSG00000127314	-0.2683512955334352	[501,391]	[578,440,426]	-4	hSpCas9	negative selection	4850427
68652031	68652053	12	+	27760321	HT29	viability after 7 days	ATCTTGGATACTGCAGGAACGG	RAP1B	ENSG00000127314	-0.10547871661708896	[248,194]	[297,352,152]	-1	hSpCas9	negative selection	4850428
68656321	68656343	12	+	27760321	HT29	viability after 7 days	GTTGGTAATAAGTGTGACTTGG	RAP1B	ENSG00000127314	-0.4557656833327395	[134,105]	[34,251,42]	-6	hSpCas9	negative selection	4850429
68656352	68656374	12	+	27760321	HT29	viability after 7 days	GAGTTGTAGGGAAGGAACAAGG	RAP1B	ENSG00000127314	0.07578914413304005	[179,140]	[222,241,188]	1	hSpCas9	negative selection	4850430
68654137	68654159	12	+	27760321	HT29	viability after 7 days	TATACATGAAAAATGGACAAGG	RAP1B	ENSG00000127314	-1.0287626454697874	[12,9]	[15,0,5]	-8	hSpCas9	negative selection	4850431
68654176	68654198	12	-	27760321	HT29	viability after 7 days	AATGTGGACTGTGCTGTGATGG	RAP1B	ENSG00000127314	-0.48047229648407447	[631,492]	[742,505,342]	-6	hSpCas9	negative selection	4850432
68654191	68654213	12	-	27760321	HT29	viability after 7 days	TCTTGTAAATCGTTAAATGTGG	RAP1B	ENSG00000127314	-0.3597438306570466	[32,25]	[35,4,47]	-5	hSpCas9	negative selection	4850433
68654213	68654235	12	-	27760321	HT29	viability after 7 days	TCGAAGAATCTGTTCTCTCAGG	RAP1B	ENSG00000127314	0.024676196498234493	[178,139]	[176,295,149]	0	hSpCas9	negative selection	4850434
68650442	68650464	12	-	27760321	HT29	viability after 25 days	TATAAGAATCTTCTATCGTAGG	RAP1B	ENSG00000127314	-3.3639995037674826	[9,7]	[0,0,0]	-9	hSpCas9	negative selection	4933889
68651991	68652013	12	-	27760321	HT29	viability after 25 days	TGCATCTACTTCAACTTGCTGG	RAP1B	ENSG00000127314	-0.2574669023849957	[501,391]	[417,479,378]	-3	hSpCas9	negative selection	4933890
68652031	68652053	12	+	27760321	HT29	viability after 25 days	ATCTTGGATACTGCAGGAACGG	RAP1B	ENSG00000127314	-0.18576372003494945	[248,194]	[351,161,137]	-2	hSpCas9	negative selection	4933891
68656321	68656343	12	+	27760321	HT29	viability after 25 days	GTTGGTAATAAGTGTGACTTGG	RAP1B	ENSG00000127314	-0.29569497672489486	[134,105]	[107,131,94]	-3	hSpCas9	negative selection	4933892
68656352	68656374	12	+	27760321	HT29	viability after 25 days	GAGTTGTAGGGAAGGAACAAGG	RAP1B	ENSG00000127314	-1.9852336810539877	[179,140]	[27,57,54]	-8	hSpCas9	negative selection	4933893
68654137	68654159	12	+	27760321	HT29	viability after 25 days	TATACATGAAAAATGGACAAGG	RAP1B	ENSG00000127314	0.09450302153547607	[12,9]	[8,30,0]	0	hSpCas9	negative selection	4933894
68654176	68654198	12	-	27760321	HT29	viability after 25 days	AATGTGGACTGTGCTGTGATGG	RAP1B	ENSG00000127314	-0.15153789625119474	[631,492]	[452,652,643]	-1	hSpCas9	negative selection	4933895
68654191	68654213	12	-	27760321	HT29	viability after 25 days	TCTTGTAAATCGTTAAATGTGG	RAP1B	ENSG00000127314	-2.0715602418677124	[32,25]	[1,0,22]	-8	hSpCas9	negative selection	4933896
68654213	68654235	12	-	27760321	HT29	viability after 25 days	TCGAAGAATCTGTTCTCTCAGG	RAP1B	ENSG00000127314	-0.5691947960807451	[178,139]	[47,237,82]	-5	hSpCas9	negative selection	4933897
68650442	68650464	12	-	27760321	HT29	viability after 22 days	TATAAGAATCTTCTATCGTAGG	RAP1B	ENSG00000127314	-3.381318135626742	[9,7]	[0,0,0]	-9	hSpCas9	negative selection	5017352
68651991	68652013	12	-	27760321	HT29	viability after 22 days	TGCATCTACTTCAACTTGCTGG	RAP1B	ENSG00000127314	0.13000876859338711	[501,391]	[479,631,586]	1	hSpCas9	negative selection	5017353
68652031	68652053	12	+	27760321	HT29	viability after 22 days	ATCTTGGATACTGCAGGAACGG	RAP1B	ENSG00000127314	-0.28855542203431583	[248,194]	[366,178,78]	-3	hSpCas9	negative selection	5017354
68656321	68656343	12	+	27760321	HT29	viability after 22 days	GTTGGTAATAAGTGTGACTTGG	RAP1B	ENSG00000127314	-0.1048089522082527	[134,105]	[134,188,63]	-1	hSpCas9	negative selection	5017355
68656352	68656374	12	+	27760321	HT29	viability after 22 days	GAGTTGTAGGGAAGGAACAAGG	RAP1B	ENSG00000127314	-2.5135035778182226	[179,140]	[50,13,31]	-8	hSpCas9	negative selection	5017356
68654137	68654159	12	+	27760321	HT29	viability after 22 days	TATACATGAAAAATGGACAAGG	RAP1B	ENSG00000127314	0.6366099964181497	[12,9]	[13,40,6]	7	hSpCas9	negative selection	5017357
68654176	68654198	12	-	27760321	HT29	viability after 22 days	AATGTGGACTGTGCTGTGATGG	RAP1B	ENSG00000127314	-0.331290907881815	[631,492]	[455,698,395]	-3	hSpCas9	negative selection	5017358
68654191	68654213	12	-	27760321	HT29	viability after 22 days	TCTTGTAAATCGTTAAATGTGG	RAP1B	ENSG00000127314	-1.2030680790612838	[32,25]	[30,0,11]	-7	hSpCas9	negative selection	5017359
68654213	68654235	12	-	27760321	HT29	viability after 22 days	TCGAAGAATCTGTTCTCTCAGG	RAP1B	ENSG00000127314	0.2553797876462408	[178,139]	[181,300,177]	2	hSpCas9	negative selection	5017360
68650442	68650464	12	-	27760321	HT29	viability after 19 days	TATAAGAATCTTCTATCGTAGG	RAP1B	ENSG00000127314	-3.365478083203529	[9,7]	[0,0,0]	-9	hSpCas9	negative selection	5100815
68651991	68652013	12	-	27760321	HT29	viability after 19 days	TGCATCTACTTCAACTTGCTGG	RAP1B	ENSG00000127314	-0.10387112747986557	[501,391]	[522,491,418]	-1	hSpCas9	negative selection	5100816
68652031	68652053	12	+	27760321	HT29	viability after 19 days	ATCTTGGATACTGCAGGAACGG	RAP1B	ENSG00000127314	-0.16950156621279144	[248,194]	[453,124,125]	-1	hSpCas9	negative selection	5100817
68656321	68656343	12	+	27760321	HT29	viability after 19 days	GTTGGTAATAAGTGTGACTTGG	RAP1B	ENSG00000127314	-0.3239513932616209	[134,105]	[206,90,44]	-3	hSpCas9	negative selection	5100818
68656352	68656374	12	+	27760321	HT29	viability after 19 days	GAGTTGTAGGGAAGGAACAAGG	RAP1B	ENSG00000127314	-3.053663217992666	[179,140]	[10,0,51]	-8	hSpCas9	negative selection	5100819
68654137	68654159	12	+	27760321	HT29	viability after 19 days	TATACATGAAAAATGGACAAGG	RAP1B	ENSG00000127314	0.29400349747507537	[12,9]	[16,30,0]	3	hSpCas9	negative selection	5100820
68654176	68654198	12	-	27760321	HT29	viability after 19 days	AATGTGGACTGTGCTGTGATGG	RAP1B	ENSG00000127314	0.2896284783235722	[631,492]	[603,1341,407]	2	hSpCas9	negative selection	5100821
68654191	68654213	12	-	27760321	HT29	viability after 19 days	TCTTGTAAATCGTTAAATGTGG	RAP1B	ENSG00000127314	0.4806022342622067	[32,25]	[12,4,116]	5	hSpCas9	negative selection	5100822
68654213	68654235	12	-	27760321	HT29	viability after 19 days	TCGAAGAATCTGTTCTCTCAGG	RAP1B	ENSG00000127314	-1.3773389617343657	[178,139]	[60,140,9]	-7	hSpCas9	negative selection	5100823
68650442	68650464	12	-	27760321	HT29	viability after 16 days	TATAAGAATCTTCTATCGTAGG	RAP1B	ENSG00000127314	-2.070949866253602	[9,7]	[0,4,0]	-8	hSpCas9	negative selection	5184278
68651991	68652013	12	-	27760321	HT29	viability after 16 days	TGCATCTACTTCAACTTGCTGG	RAP1B	ENSG00000127314	0.09836376411875752	[501,391]	[449,499,648]	1	hSpCas9	negative selection	5184279
68652031	68652053	12	+	27760321	HT29	viability after 16 days	ATCTTGGATACTGCAGGAACGG	RAP1B	ENSG00000127314	-0.3480195551579375	[248,194]	[184,330,64]	-4	hSpCas9	negative selection	5184280
68656321	68656343	12	+	27760321	HT29	viability after 16 days	GTTGGTAATAAGTGTGACTTGG	RAP1B	ENSG00000127314	0.30767562467131726	[134,105]	[159,93,247]	3	hSpCas9	negative selection	5184281
68656352	68656374	12	+	27760321	HT29	viability after 16 days	GAGTTGTAGGGAAGGAACAAGG	RAP1B	ENSG00000127314	-1.985139396128459	[179,140]	[36,56,40]	-8	hSpCas9	negative selection	5184282
68654137	68654159	12	+	27760321	HT29	viability after 16 days	TATACATGAAAAATGGACAAGG	RAP1B	ENSG00000127314	-1.2679276052974382	[12,9]	[3,0,10]	-7	hSpCas9	negative selection	5184283
68654176	68654198	12	-	27760321	HT29	viability after 16 days	AATGTGGACTGTGCTGTGATGG	RAP1B	ENSG00000127314	-0.1389720278235964	[631,492]	[921,439,388]	-1	hSpCas9	negative selection	5184284
68654191	68654213	12	-	27760321	HT29	viability after 16 days	TCTTGTAAATCGTTAAATGTGG	RAP1B	ENSG00000127314	-3.8038781448320496	[32,25]	[0,0,4]	-9	hSpCas9	negative selection	5184285
68654213	68654235	12	-	27760321	HT29	viability after 16 days	TCGAAGAATCTGTTCTCTCAGG	RAP1B	ENSG00000127314	-0.3244523255674101	[178,139]	[76,309,29]	-3	hSpCas9	negative selection	5184286
68650442	68650464	12	-	27760321	HT29	viability after 13 days	TATAAGAATCTTCTATCGTAGG	RAP1B	ENSG00000127314	-3.386301030226745	[9,7]	[0,0,0]	-9	hSpCas9	negative selection	5267741
68651991	68652013	12	-	27760321	HT29	viability after 13 days	TGCATCTACTTCAACTTGCTGG	RAP1B	ENSG00000127314	-0.1510806276706564	[501,391]	[461,454,482]	-2	hSpCas9	negative selection	5267742
68652031	68652053	12	+	27760321	HT29	viability after 13 days	ATCTTGGATACTGCAGGAACGG	RAP1B	ENSG00000127314	-0.308713053681837	[248,194]	[207,260,157]	-4	hSpCas9	negative selection	5267743
68656321	68656343	12	+	27760321	HT29	viability after 13 days	GTTGGTAATAAGTGTGACTTGG	RAP1B	ENSG00000127314	0.14303774729392504	[134,105]	[238,51,170]	1	hSpCas9	negative selection	5267744
68656352	68656374	12	+	27760321	HT29	viability after 13 days	GAGTTGTAGGGAAGGAACAAGG	RAP1B	ENSG00000127314	-0.8551576816012998	[179,140]	[56,217,37]	-7	hSpCas9	negative selection	5267745
68654137	68654159	12	+	27760321	HT29	viability after 13 days	TATACATGAAAAATGGACAAGG	RAP1B	ENSG00000127314	-1.5773248953070347	[12,9]	[0,0,10]	-8	hSpCas9	negative selection	5267746
68654176	68654198	12	-	27760321	HT29	viability after 13 days	AATGTGGACTGTGCTGTGATGG	RAP1B	ENSG00000127314	0.055413389329739826	[631,492]	[500,862,670]	0	hSpCas9	negative selection	5267747
68654191	68654213	12	-	27760321	HT29	viability after 13 days	TCTTGTAAATCGTTAAATGTGG	RAP1B	ENSG00000127314	-0.20739788523259328	[32,25]	[5,69,13]	-2	hSpCas9	negative selection	5267748
68654213	68654235	12	-	27760321	HT29	viability after 13 days	TCGAAGAATCTGTTCTCTCAGG	RAP1B	ENSG00000127314	0.3207947488638505	[178,139]	[259,332,107]	4	hSpCas9	negative selection	5267749
68650442	68650464	12	-	27760321	HT29	viability after 10 days	TATAAGAATCTTCTATCGTAGG	RAP1B	ENSG00000127314	-0.13393038730712092	[9,7]	[18,10,0]	-2	hSpCas9	negative selection	5351204
68651991	68652013	12	-	27760321	HT29	viability after 10 days	TGCATCTACTTCAACTTGCTGG	RAP1B	ENSG00000127314	-0.28402028084964087	[501,391]	[511,532,334]	-4	hSpCas9	negative selection	5351205
68652031	68652053	12	+	27760321	HT29	viability after 10 days	ATCTTGGATACTGCAGGAACGG	RAP1B	ENSG00000127314	-0.23286086164991082	[248,194]	[268,206,230]	-3	hSpCas9	negative selection	5351206
68656321	68656343	12	+	27760321	HT29	viability after 10 days	GTTGGTAATAAGTGTGACTTGG	RAP1B	ENSG00000127314	-0.1365383992060083	[134,105]	[7,159,240]	-2	hSpCas9	negative selection	5351207
68656352	68656374	12	+	27760321	HT29	viability after 10 days	GAGTTGTAGGGAAGGAACAAGG	RAP1B	ENSG00000127314	-1.5962428239172548	[179,140]	[121,23,51]	-8	hSpCas9	negative selection	5351208
68654137	68654159	12	+	27760321	HT29	viability after 10 days	TATACATGAAAAATGGACAAGG	RAP1B	ENSG00000127314	1.1255418427908719	[12,9]	[20,17,53]	9	hSpCas9	negative selection	5351209
68654176	68654198	12	-	27760321	HT29	viability after 10 days	AATGTGGACTGTGCTGTGATGG	RAP1B	ENSG00000127314	-0.30262664978193626	[631,492]	[450,940,331]	-4	hSpCas9	negative selection	5351210
68654191	68654213	12	-	27760321	HT29	viability after 10 days	TCTTGTAAATCGTTAAATGTGG	RAP1B	ENSG00000127314	0.19687463388738635	[32,25]	[3,84,38]	2	hSpCas9	negative selection	5351211
68654213	68654235	12	-	27760321	HT29	viability after 10 days	TCGAAGAATCTGTTCTCTCAGG	RAP1B	ENSG00000127314	0.05234983226347434	[178,139]	[245,317,61]	0	hSpCas9	negative selection	5351212
68650442	68650464	12	-	27760321	MOLM13	viability	TATAAGAATCTTCTATCGTAGG	RAP1B	ENSG00000127314	-2.6870775482140807	[12,9]	[0,0]	-8	hSpCas9	negative selection	5434667
68651991	68652013	12	-	27760321	MOLM13	viability	TGCATCTACTTCAACTTGCTGG	RAP1B	ENSG00000127314	0.45318317848586676	[708,501]	[493,435]	3	hSpCas9	negative selection	5434668
68652031	68652053	12	+	27760321	MOLM13	viability	ATCTTGGATACTGCAGGAACGG	RAP1B	ENSG00000127314	-0.047020534525271995	[251,248]	[201,81]	0	hSpCas9	negative selection	5434669
68656321	68656343	12	+	27760321	MOLM13	viability	GTTGGTAATAAGTGTGACTTGG	RAP1B	ENSG00000127314	1.4570866102416444	[175,134]	[49,399]	8	hSpCas9	negative selection	5434670
68656352	68656374	12	+	27760321	MOLM13	viability	GAGTTGTAGGGAAGGAACAAGG	RAP1B	ENSG00000127314	1.1825457937369808	[199,179]	[443,71]	8	hSpCas9	negative selection	5434671
68654137	68654159	12	+	27760321	MOLM13	viability	TATACATGAAAAATGGACAAGG	RAP1B	ENSG00000127314	-2.6597298178959283	[8,12]	[0,0]	-8	hSpCas9	negative selection	5434672
68654176	68654198	12	-	27760321	MOLM13	viability	AATGTGGACTGTGCTGTGATGG	RAP1B	ENSG00000127314	1.1686301974310835	[709,631]	[1242,514]	7	hSpCas9	negative selection	5434673
68654191	68654213	12	-	27760321	MOLM13	viability	TCTTGTAAATCGTTAAATGTGG	RAP1B	ENSG00000127314	-4.182678687305473	[30,32]	[0,0]	-9	hSpCas9	negative selection	5434674
68654213	68654235	12	-	27760321	MOLM13	viability	TCGAAGAATCTGTTCTCTCAGG	RAP1B	ENSG00000127314	0.4022957562668331	[220,178]	[237,71]	3	hSpCas9	negative selection	5434675
68611281	68611304	12	+	27661255	K562	viability	GAACAGCGCGCTTTGCGGAAGGG	RAP1B	ENSG00000127314	0.25183892861485824	[506,533]	[553,443]	8	dCas9-KRAB	negative selection	5506165
68610885	68610908	12	-	27661255	K562	viability	GGCGATGTCGCCTTGACGTCAGG	RAP1B	ENSG00000127314	-0.06317426938127219	[922,801]	[706,621]	-2	dCas9-KRAB	negative selection	5506166
68611065	68611088	12	-	27661255	K562	viability	GCCGCCGCGGCTTCCCTCAGCGG	RAP1B	ENSG00000127314	-0.02772164160362206	[601,635]	[476,490]	-1	dCas9-KRAB	negative selection	5506167
68611351	68611374	12	-	27661255	K562	viability	GCTGAAGAGAGCGGGCGGGTGGG	RAP1B	ENSG00000127314	0.026328343427128642	[1066,1192]	[1046,806]	0	dCas9-KRAB	negative selection	5506168
68611359	68611382	12	-	27661255	K562	viability	GGACGCGGGCTGAAGAGAGCGGG	RAP1B	ENSG00000127314	0.1252136813492386	[1526,1240]	[1314,1120]	4	dCas9-KRAB	negative selection	5506169
68611374	68611397	12	-	27661255	K562	viability	GGGAGAAGCTGCGGCGGACGCGG	RAP1B	ENSG00000127314	-0.0982414138658485	[1246,1333]	[1085,855]	-4	dCas9-KRAB	negative selection	5506170
68650447	68650470	12	+	27260156	BXPC3	viability	GATAGAAGATTCTTATAGAAAGG	RAP1B	ENSG00000127314	-0.27121275364658004	[33]	[11,21,27,61]	-6	hSpCas9	negative selection	5566315
68656303	68656326	12	+	27260156	BXPC3	viability	TAGGTTCCAATGATTCTTGTTGG	RAP1B	ENSG00000127314	0.44790432063188645	[225]	[244,310,352,396]	8	hSpCas9	negative selection	5566316
68650397	68650420	12	+	27260156	BXPC3	viability	CAGACTGTACAATTTGTTCAAGG	RAP1B	ENSG00000127314	0.12701774566003812	[484]	[440,605,567,612]	3	hSpCas9	negative selection	5566317
68656428	68656451	12	+	27260156	BXPC3	viability	ATCAAAAATAAATGTTAATGAGG	RAP1B	ENSG00000127314	-0.010057718526133241	[356]	[403,348,364,357]	0	hSpCas9	negative selection	5630573
68652015	68652038	12	+	27260156	BXPC3	viability	ACAGTGTATGCTTGAAATCTTGG	RAP1B	ENSG00000127314	0.1545257643841602	[673]	[801,654,772,924]	3	hSpCas9	negative selection	5630574
68650447	68650470	12	+	27260156	A673	viability	GATAGAAGATTCTTATAGAAAGG	RAP1B	ENSG00000127314	0.060255515235610346	[33]	[95,32,18,27]	1	hSpCas9	negative selection	5687566
68656303	68656326	12	+	27260156	A673	viability	TAGGTTCCAATGATTCTTGTTGG	RAP1B	ENSG00000127314	0.29545415222683435	[225]	[305,270,392,360]	7	hSpCas9	negative selection	5687567
68650397	68650420	12	+	27260156	A673	viability	CAGACTGTACAATTTGTTCAAGG	RAP1B	ENSG00000127314	0.16037754162439952	[484]	[689,563,532,832]	4	hSpCas9	negative selection	5687568
68656428	68656451	12	+	27260156	A673	viability	ATCAAAAATAAATGTTAATGAGG	RAP1B	ENSG00000127314	-0.16942634091702785	[356]	[441,416,345,321]	-4	hSpCas9	negative selection	5751824
68652015	68652038	12	+	27260156	A673	viability	ACAGTGTATGCTTGAAATCTTGG	RAP1B	ENSG00000127314	0.18496921889125084	[673]	[1027,853,913,894]	4	hSpCas9	negative selection	5751825
68650447	68650470	12	+	27260156	A375	viability	GATAGAAGATTCTTATAGAAAGG	RAP1B	ENSG00000127314	-0.787604525327394	[33]	[29,6,31,20]	-7	hSpCas9	negative selection	5808817
68656303	68656326	12	+	27260156	A375	viability	TAGGTTCCAATGATTCTTGTTGG	RAP1B	ENSG00000127314	-0.38045540271768896	[225]	[252,289,124,159]	-5	hSpCas9	negative selection	5808818
68650397	68650420	12	+	27260156	A375	viability	CAGACTGTACAATTTGTTCAAGG	RAP1B	ENSG00000127314	0.637238904945356	[484]	[694,1013,1049,789]	8	hSpCas9	negative selection	5808819
68656428	68656451	12	+	27260156	A375	viability	ATCAAAAATAAATGTTAATGAGG	RAP1B	ENSG00000127314	0.15334493489412532	[356]	[711,307,503,325]	2	hSpCas9	negative selection	5873075
68652015	68652038	12	+	27260156	A375	viability	ACAGTGTATGCTTGAAATCTTGG	RAP1B	ENSG00000127314	0.292847089763823	[673]	[1117,1173,1051,585]	4	hSpCas9	negative selection	5873076
68650447	68650470	12	+	27260156	COLO741	viability	GATAGAAGATTCTTATAGAAAGG	RAP1B	ENSG00000127314	-0.06834505504624522	[33]	[20,38,60]	-1	hSpCas9	negative selection	5930068
68656303	68656326	12	+	27260156	COLO741	viability	TAGGTTCCAATGATTCTTGTTGG	RAP1B	ENSG00000127314	0.06258485196319663	[225]	[270,349,281]	1	hSpCas9	negative selection	5930069
68650397	68650420	12	+	27260156	COLO741	viability	CAGACTGTACAATTTGTTCAAGG	RAP1B	ENSG00000127314	0.005504241300355095	[484]	[666,697,511]	0	hSpCas9	negative selection	5930070
68656428	68656451	12	+	27260156	COLO741	viability	ATCAAAAATAAATGTTAATGAGG	RAP1B	ENSG00000127314	-0.3121948010957391	[356]	[468,304,337]	-6	hSpCas9	negative selection	5994326
68652015	68652038	12	+	27260156	COLO741	viability	ACAGTGTATGCTTGAAATCTTGG	RAP1B	ENSG00000127314	0.29217390607996796	[673]	[837,1205,1095]	6	hSpCas9	negative selection	5994327
68650447	68650470	12	+	27260156	CAL120	viability	GATAGAAGATTCTTATAGAAAGG	RAP1B	ENSG00000127314	-0.4684048891111994	[33]	[30,41,18]	-6	hSpCas9	negative selection	6051319
68656303	68656326	12	+	27260156	CAL120	viability	TAGGTTCCAATGATTCTTGTTGG	RAP1B	ENSG00000127314	0.19393757841453374	[225]	[424,261,293]	3	hSpCas9	negative selection	6051320
68650397	68650420	12	+	27260156	CAL120	viability	CAGACTGTACAATTTGTTCAAGG	RAP1B	ENSG00000127314	0.4987612837732581	[484]	[610,519,1380]	7	hSpCas9	negative selection	6051321
68656428	68656451	12	+	27260156	CAL120	viability	ATCAAAAATAAATGTTAATGAGG	RAP1B	ENSG00000127314	0.521266357843823	[356]	[754,695,481]	7	hSpCas9	negative selection	6115577
68652015	68652038	12	+	27260156	CAL120	viability	ACAGTGTATGCTTGAAATCTTGG	RAP1B	ENSG00000127314	0.5265690308717546	[673]	[1164,1494,961]	7	hSpCas9	negative selection	6115578
68650447	68650470	12	+	27260156	CADOES1	viability	GATAGAAGATTCTTATAGAAAGG	RAP1B	ENSG00000127314	0.11005448161463383	[33]	[14,30,44,45]	2	hSpCas9	negative selection	6172570
68656303	68656326	12	+	27260156	CADOES1	viability	TAGGTTCCAATGATTCTTGTTGG	RAP1B	ENSG00000127314	0.4679729201680074	[225]	[179,420,334,224]	7	hSpCas9	negative selection	6172571
68650397	68650420	12	+	27260156	CADOES1	viability	CAGACTGTACAATTTGTTCAAGG	RAP1B	ENSG00000127314	0.538738326282047	[484]	[576,712,610,722]	8	hSpCas9	negative selection	6172572
68656428	68656451	12	+	27260156	CADOES1	viability	ATCAAAAATAAATGTTAATGAGG	RAP1B	ENSG00000127314	0.047872459488523034	[356]	[394,379,302,292]	0	hSpCas9	negative selection	6236828
68652015	68652038	12	+	27260156	CADOES1	viability	ACAGTGTATGCTTGAAATCTTGG	RAP1B	ENSG00000127314	0.20393677911062935	[673]	[762,751,628,744]	3	hSpCas9	negative selection	6236829
68650447	68650470	12	+	27260156	EWS502	viability	GATAGAAGATTCTTATAGAAAGG	RAP1B	ENSG00000127314	0.8292735931336774	[33]	[45,50,111,48]	9	hSpCas9	negative selection	6293821
68656303	68656326	12	+	27260156	EWS502	viability	TAGGTTCCAATGATTCTTGTTGG	RAP1B	ENSG00000127314	0.42977403965225935	[225]	[239,513,279,250]	7	hSpCas9	negative selection	6293822
68650397	68650420	12	+	27260156	EWS502	viability	CAGACTGTACAATTTGTTCAAGG	RAP1B	ENSG00000127314	0.336493364127066	[484]	[510,773,572,751]	6	hSpCas9	negative selection	6293823
68656428	68656451	12	+	27260156	EWS502	viability	ATCAAAAATAAATGTTAATGAGG	RAP1B	ENSG00000127314	0.19408970434401202	[356]	[445,232,494,571]	3	hSpCas9	negative selection	6358079
68652015	68652038	12	+	27260156	EWS502	viability	ACAGTGTATGCTTGAAATCTTGG	RAP1B	ENSG00000127314	0.0016897821137338287	[673]	[518,510,911,966]	0	hSpCas9	negative selection	6358080
68650447	68650470	12	+	27260156	EW8	viability	GATAGAAGATTCTTATAGAAAGG	RAP1B	ENSG00000127314	-0.16345105451169006	[33]	[26,18,21,30]	-3	hSpCas9	negative selection	6415072
68656303	68656326	12	+	27260156	EW8	viability	TAGGTTCCAATGATTCTTGTTGG	RAP1B	ENSG00000127314	0.479761059661283	[225]	[375,309,146,219]	8	hSpCas9	negative selection	6415073
68650397	68650420	12	+	27260156	EW8	viability	CAGACTGTACAATTTGTTCAAGG	RAP1B	ENSG00000127314	0.4884190703268404	[484]	[865,404,433,552]	8	hSpCas9	negative selection	6415074
68656428	68656451	12	+	27260156	EW8	viability	ATCAAAAATAAATGTTAATGAGG	RAP1B	ENSG00000127314	-0.12528510003145005	[356]	[504,176,202,211]	-2	hSpCas9	negative selection	6479330
68652015	68652038	12	+	27260156	EW8	viability	ACAGTGTATGCTTGAAATCTTGG	RAP1B	ENSG00000127314	0.07921043342395384	[673]	[782,714,395,466]	1	hSpCas9	negative selection	6479331
68650447	68650470	12	+	27260156	CORL105	viability	GATAGAAGATTCTTATAGAAAGG	RAP1B	ENSG00000127314	-0.09807768607265643	[33]	[8,66,60,13]	-2	hSpCas9	negative selection	6536323
68656303	68656326	12	+	27260156	CORL105	viability	TAGGTTCCAATGATTCTTGTTGG	RAP1B	ENSG00000127314	-0.038923900813369716	[225]	[238,220,376,211]	0	hSpCas9	negative selection	6536324
68650397	68650420	12	+	27260156	CORL105	viability	CAGACTGTACAATTTGTTCAAGG	RAP1B	ENSG00000127314	0.3977840510212657	[484]	[732,749,889,640]	7	hSpCas9	negative selection	6536325
68656428	68656451	12	+	27260156	CORL105	viability	ATCAAAAATAAATGTTAATGAGG	RAP1B	ENSG00000127314	-0.10144675574605161	[356]	[360,410,372,408]	-2	hSpCas9	negative selection	6600581
68652015	68652038	12	+	27260156	CORL105	viability	ACAGTGTATGCTTGAAATCTTGG	RAP1B	ENSG00000127314	0.0025722822737545004	[673]	[724,797,934,723]	0	hSpCas9	negative selection	6600582
68650447	68650470	12	+	27260156	HS294T	viability	GATAGAAGATTCTTATAGAAAGG	RAP1B	ENSG00000127314	0.01439796138236149	[33]	[11,2,17,21]	0	hSpCas9	negative selection	6657574
68656303	68656326	12	+	27260156	HS294T	viability	TAGGTTCCAATGATTCTTGTTGG	RAP1B	ENSG00000127314	0.5790904100731034	[225]	[102,139,185,87]	7	hSpCas9	negative selection	6657575
68650397	68650420	12	+	27260156	HS294T	viability	CAGACTGTACAATTTGTTCAAGG	RAP1B	ENSG00000127314	0.3459812949781922	[484]	[217,262,252,215]	4	hSpCas9	negative selection	6657576
68656428	68656451	12	+	27260156	HS294T	viability	ATCAAAAATAAATGTTAATGAGG	RAP1B	ENSG00000127314	0.3612391527906009	[356]	[241,107,210,136]	5	hSpCas9	negative selection	6721832
68652015	68652038	12	+	27260156	HS294T	viability	ACAGTGTATGCTTGAAATCTTGG	RAP1B	ENSG00000127314	0.0073668841671772345	[673]	[180,438,174,251]	0	hSpCas9	negative selection	6721833
68650447	68650470	12	+	27260156	HCC44	viability	GATAGAAGATTCTTATAGAAAGG	RAP1B	ENSG00000127314	1.3454167446666117	[33]	[52,97,239,21]	9	hSpCas9	negative selection	6778825
68656303	68656326	12	+	27260156	HCC44	viability	TAGGTTCCAATGATTCTTGTTGG	RAP1B	ENSG00000127314	0.8159406713395504	[225]	[748,260,487,361]	9	hSpCas9	negative selection	6778826
68650397	68650420	12	+	27260156	HCC44	viability	CAGACTGTACAATTTGTTCAAGG	RAP1B	ENSG00000127314	0.33132468617511945	[484]	[842,289,1001,742]	5	hSpCas9	negative selection	6778827
68656428	68656451	12	+	27260156	HCC44	viability	ATCAAAAATAAATGTTAATGAGG	RAP1B	ENSG00000127314	0.22075209707244328	[356]	[438,420,541,491]	3	hSpCas9	negative selection	6843083
68652015	68652038	12	+	27260156	HCC44	viability	ACAGTGTATGCTTGAAATCTTGG	RAP1B	ENSG00000127314	0.36391687625639435	[673]	[955,914,829,1188]	6	hSpCas9	negative selection	6843084
68650447	68650470	12	+	27260156	G402	viability	GATAGAAGATTCTTATAGAAAGG	RAP1B	ENSG00000127314	0.5477017932407926	[33]	[158,38,32,25]	6	hSpCas9	negative selection	6900076
68656303	68656326	12	+	27260156	G402	viability	TAGGTTCCAATGATTCTTGTTGG	RAP1B	ENSG00000127314	0.4832865750916949	[225]	[739,435,146,276]	6	hSpCas9	negative selection	6900077
68650397	68650420	12	+	27260156	G402	viability	CAGACTGTACAATTTGTTCAAGG	RAP1B	ENSG00000127314	1.0293308044964198	[484]	[962,1407,1728,726]	9	hSpCas9	negative selection	6900078
68656428	68656451	12	+	27260156	G402	viability	ATCAAAAATAAATGTTAATGAGG	RAP1B	ENSG00000127314	0.04274238191632618	[356]	[569,434,359,444]	0	hSpCas9	negative selection	6964334
68652015	68652038	12	+	27260156	G402	viability	ACAGTGTATGCTTGAAATCTTGG	RAP1B	ENSG00000127314	0.8418391510862302	[673]	[2059,1533,1449,959]	9	hSpCas9	negative selection	6964335
68650447	68650470	12	+	27260156	L33	viability	GATAGAAGATTCTTATAGAAAGG	RAP1B	ENSG00000127314	0.8713900938285484	[33]	[81,18,15,93]	9	hSpCas9	negative selection	7021327
68656303	68656326	12	+	27260156	L33	viability	TAGGTTCCAATGATTCTTGTTGG	RAP1B	ENSG00000127314	0.29590445699980905	[225]	[312,105,195,225]	6	hSpCas9	negative selection	7021328
68650397	68650420	12	+	27260156	L33	viability	CAGACTGTACAATTTGTTCAAGG	RAP1B	ENSG00000127314	0.45659751735616017	[484]	[549,325,344,768]	8	hSpCas9	negative selection	7021329
68656428	68656451	12	+	27260156	L33	viability	ATCAAAAATAAATGTTAATGAGG	RAP1B	ENSG00000127314	0.1707804531746911	[356]	[422,165,288,319]	4	hSpCas9	negative selection	7085585
68652015	68652038	12	+	27260156	L33	viability	ACAGTGTATGCTTGAAATCTTGG	RAP1B	ENSG00000127314	-0.5442762899106324	[673]	[365,232,305,429]	-8	hSpCas9	negative selection	7085586
68650447	68650470	12	+	27260156	K562	viability	GATAGAAGATTCTTATAGAAAGG	RAP1B	ENSG00000127314	0.7902131672526775	[33]	[35,118,15,40]	8	hSpCas9	negative selection	7142578
68656303	68656326	12	+	27260156	K562	viability	TAGGTTCCAATGATTCTTGTTGG	RAP1B	ENSG00000127314	0.41798303454266417	[225]	[221,314,222,304]	5	hSpCas9	negative selection	7142579
68650397	68650420	12	+	27260156	K562	viability	CAGACTGTACAATTTGTTCAAGG	RAP1B	ENSG00000127314	0.6194818366880939	[484]	[671,954,667,394]	7	hSpCas9	negative selection	7142580
68656428	68656451	12	+	27260156	K562	viability	ATCAAAAATAAATGTTAATGAGG	RAP1B	ENSG00000127314	0.26140793218128827	[356]	[368,419,381,350]	3	hSpCas9	negative selection	7206836
68652015	68652038	12	+	27260156	K562	viability	ACAGTGTATGCTTGAAATCTTGG	RAP1B	ENSG00000127314	0.5083235195783853	[673]	[880,1121,607,809]	6	hSpCas9	negative selection	7206837
68650447	68650470	12	+	27260156	HT29	viability	GATAGAAGATTCTTATAGAAAGG	RAP1B	ENSG00000127314	-0.4826636234324946	[33]	[24,22,28,38]	-7	hSpCas9	negative selection	7263829
68656303	68656326	12	+	27260156	HT29	viability	TAGGTTCCAATGATTCTTGTTGG	RAP1B	ENSG00000127314	0.45345172243652865	[225]	[209,519,452,324]	8	hSpCas9	negative selection	7263830
68650397	68650420	12	+	27260156	HT29	viability	CAGACTGTACAATTTGTTCAAGG	RAP1B	ENSG00000127314	0.36191743754448646	[484]	[901,806,694,649]	7	hSpCas9	negative selection	7263831
68656428	68656451	12	+	27260156	HT29	viability	ATCAAAAATAAATGTTAATGAGG	RAP1B	ENSG00000127314	0.017586614871451856	[356]	[454,581,394,346]	0	hSpCas9	negative selection	7328087
68652015	68652038	12	+	27260156	HT29	viability	ACAGTGTATGCTTGAAATCTTGG	RAP1B	ENSG00000127314	0.3838265602750519	[673]	[1057,1013,1239,963]	7	hSpCas9	negative selection	7328088
68650447	68650470	12	+	27260156	MHHES1	viability	GATAGAAGATTCTTATAGAAAGG	RAP1B	ENSG00000127314	0.39412527626150373	[33]	[25,48,75,46]	7	hSpCas9	negative selection	7385080
68656303	68656326	12	+	27260156	MHHES1	viability	TAGGTTCCAATGATTCTTGTTGG	RAP1B	ENSG00000127314	0.4160210367290206	[225]	[440,292,305,321]	7	hSpCas9	negative selection	7385081
68650397	68650420	12	+	27260156	MHHES1	viability	CAGACTGTACAATTTGTTCAAGG	RAP1B	ENSG00000127314	0.4167988016346793	[484]	[751,832,763,595]	7	hSpCas9	negative selection	7385082
68656428	68656451	12	+	27260156	MHHES1	viability	ATCAAAAATAAATGTTAATGAGG	RAP1B	ENSG00000127314	0.23272189704861238	[356]	[436,303,616,494]	4	hSpCas9	negative selection	7449338
68652015	68652038	12	+	27260156	MHHES1	viability	ACAGTGTATGCTTGAAATCTTGG	RAP1B	ENSG00000127314	0.04737082119205438	[673]	[874,972,617,701]	0	hSpCas9	negative selection	7449339
68650447	68650470	12	+	27260156	MEWO	viability	GATAGAAGATTCTTATAGAAAGG	RAP1B	ENSG00000127314	0.16907320201715503	[33]	[33,23,48]	4	hSpCas9	negative selection	7506331
68656303	68656326	12	+	27260156	MEWO	viability	TAGGTTCCAATGATTCTTGTTGG	RAP1B	ENSG00000127314	-0.10280384243910756	[225]	[264,162,175]	-2	hSpCas9	negative selection	7506332
68650397	68650420	12	+	27260156	MEWO	viability	CAGACTGTACAATTTGTTCAAGG	RAP1B	ENSG00000127314	0.2742236083754358	[484]	[527,562,550]	6	hSpCas9	negative selection	7506333
68656428	68656451	12	+	27260156	MEWO	viability	ATCAAAAATAAATGTTAATGAGG	RAP1B	ENSG00000127314	-0.5143807675388825	[356]	[322,173,221]	-8	hSpCas9	negative selection	7570589
68652015	68652038	12	+	27260156	MEWO	viability	ACAGTGTATGCTTGAAATCTTGG	RAP1B	ENSG00000127314	0.0019458895388498876	[673]	[884,476,581]	0	hSpCas9	negative selection	7570590
68650447	68650470	12	+	27260156	LNCAPCLONEFGC	viability	GATAGAAGATTCTTATAGAAAGG	RAP1B	ENSG00000127314	0.7557173481519182	[33]	[67,36,87,20]	9	hSpCas9	negative selection	7627582
68656303	68656326	12	+	27260156	LNCAPCLONEFGC	viability	TAGGTTCCAATGATTCTTGTTGG	RAP1B	ENSG00000127314	0.2556570919646376	[225]	[277,230,252,216]	4	hSpCas9	negative selection	7627583
68650397	68650420	12	+	27260156	LNCAPCLONEFGC	viability	CAGACTGTACAATTTGTTCAAGG	RAP1B	ENSG00000127314	0.44324483387596547	[484]	[543,423,876,597]	7	hSpCas9	negative selection	7627584
68656428	68656451	12	+	27260156	LNCAPCLONEFGC	viability	ATCAAAAATAAATGTTAATGAGG	RAP1B	ENSG00000127314	-0.20068545387108921	[356]	[269,263,309,286]	-3	hSpCas9	negative selection	7691840
68652015	68652038	12	+	27260156	LNCAPCLONEFGC	viability	ACAGTGTATGCTTGAAATCTTGG	RAP1B	ENSG00000127314	0.3575973780376249	[673]	[596,806,838,895]	5	hSpCas9	negative selection	7691841
68650447	68650470	12	+	27260156	PANC0327	viability	GATAGAAGATTCTTATAGAAAGG	RAP1B	ENSG00000127314	-0.7148508214735152	[33]	[9,40,15,2]	-7	hSpCas9	negative selection	7748833
68656303	68656326	12	+	27260156	PANC0327	viability	TAGGTTCCAATGATTCTTGTTGG	RAP1B	ENSG00000127314	0.22377412344676395	[225]	[158,166,183,429]	3	hSpCas9	negative selection	7748834
68650397	68650420	12	+	27260156	PANC0327	viability	CAGACTGTACAATTTGTTCAAGG	RAP1B	ENSG00000127314	0.5123594137338779	[484]	[758,573,589,551]	7	hSpCas9	negative selection	7748835
68656428	68656451	12	+	27260156	PANC0327	viability	ATCAAAAATAAATGTTAATGAGG	RAP1B	ENSG00000127314	-1.0002915841209554	[356]	[105,132,152,240]	-8	hSpCas9	negative selection	7813091
68652015	68652038	12	+	27260156	PANC0327	viability	ACAGTGTATGCTTGAAATCTTGG	RAP1B	ENSG00000127314	0.4001859222130051	[673]	[653,796,746,949]	6	hSpCas9	negative selection	7813092
68650447	68650470	12	+	27260156	NCIH2009	viability	GATAGAAGATTCTTATAGAAAGG	RAP1B	ENSG00000127314	0.8084404974753441	[33]	[91,37,121]	9	hSpCas9	negative selection	7870084
68656303	68656326	12	+	27260156	NCIH2009	viability	TAGGTTCCAATGATTCTTGTTGG	RAP1B	ENSG00000127314	0.5570458695874763	[225]	[627,309,489]	7	hSpCas9	negative selection	7870085
68650397	68650420	12	+	27260156	NCIH2009	viability	CAGACTGTACAATTTGTTCAAGG	RAP1B	ENSG00000127314	0.5804044196824976	[484]	[886,682,1448]	7	hSpCas9	negative selection	7870086
68656428	68656451	12	+	27260156	NCIH2009	viability	ATCAAAAATAAATGTTAATGAGG	RAP1B	ENSG00000127314	0.25971840058751305	[356]	[712,397,705]	3	hSpCas9	negative selection	7934342
68652015	68652038	12	+	27260156	NCIH2009	viability	ACAGTGTATGCTTGAAATCTTGG	RAP1B	ENSG00000127314	-0.17585052669953505	[673]	[951,714,857]	-2	hSpCas9	negative selection	7934343
68650447	68650470	12	+	27260156	NCIH1373	viability	GATAGAAGATTCTTATAGAAAGG	RAP1B	ENSG00000127314	0.7483092589075562	[33]	[50,119,26,12]	7	hSpCas9	negative selection	7991335
68656303	68656326	12	+	27260156	NCIH1373	viability	TAGGTTCCAATGATTCTTGTTGG	RAP1B	ENSG00000127314	0.36851353899368366	[225]	[372,200,360,103]	3	hSpCas9	negative selection	7991336
68650397	68650420	12	+	27260156	NCIH1373	viability	CAGACTGTACAATTTGTTCAAGG	RAP1B	ENSG00000127314	0.9168782748673504	[484]	[1096,850,1018,307]	8	hSpCas9	negative selection	7991337
68656428	68656451	12	+	27260156	NCIH1373	viability	ATCAAAAATAAATGTTAATGAGG	RAP1B	ENSG00000127314	-0.02726353870788223	[356]	[547,270,296,130]	0	hSpCas9	negative selection	8055593
68652015	68652038	12	+	27260156	NCIH1373	viability	ACAGTGTATGCTTGAAATCTTGG	RAP1B	ENSG00000127314	0.21283898596180384	[673]	[1191,837,1059,112]	2	hSpCas9	negative selection	8055594
68650447	68650470	12	+	27260156	PATU8902	viability	GATAGAAGATTCTTATAGAAAGG	RAP1B	ENSG00000127314	0.07935379677116394	[33]	[7,10,10,197]	0	hSpCas9	negative selection	8112586
68656303	68656326	12	+	27260156	PATU8902	viability	TAGGTTCCAATGATTCTTGTTGG	RAP1B	ENSG00000127314	-0.01094442572815102	[225]	[378,132,486,185]	0	hSpCas9	negative selection	8112587
68650397	68650420	12	+	27260156	PATU8902	viability	CAGACTGTACAATTTGTTCAAGG	RAP1B	ENSG00000127314	0.9691647716377271	[484]	[1451,1272,879,1849]	9	hSpCas9	negative selection	8112588
68656428	68656451	12	+	27260156	PATU8902	viability	ATCAAAAATAAATGTTAATGAGG	RAP1B	ENSG00000127314	-0.33058276418015903	[356]	[420,320,401,436]	-3	hSpCas9	negative selection	8176844
68652015	68652038	12	+	27260156	PATU8902	viability	ACAGTGTATGCTTGAAATCTTGG	RAP1B	ENSG00000127314	-0.5369416163697747	[673]	[903,798,537,328]	-5	hSpCas9	negative selection	8176845
68650447	68650470	12	+	27260156	PANC1	viability	GATAGAAGATTCTTATAGAAAGG	RAP1B	ENSG00000127314	0.5186716950465446	[33]	[60,60,39,12]	8	hSpCas9	negative selection	8233837
68656303	68656326	12	+	27260156	PANC1	viability	TAGGTTCCAATGATTCTTGTTGG	RAP1B	ENSG00000127314	0.5198385012143579	[225]	[250,432,361,121]	8	hSpCas9	negative selection	8233838
68650397	68650420	12	+	27260156	PANC1	viability	CAGACTGTACAATTTGTTCAAGG	RAP1B	ENSG00000127314	0.4252495729388227	[484]	[547,771,578,399]	7	hSpCas9	negative selection	8233839
68656428	68656451	12	+	27260156	PANC1	viability	ATCAAAAATAAATGTTAATGAGG	RAP1B	ENSG00000127314	0.28946411066808897	[356]	[464,456,240,347]	4	hSpCas9	negative selection	8298095
68652015	68652038	12	+	27260156	PANC1	viability	ACAGTGTATGCTTGAAATCTTGG	RAP1B	ENSG00000127314	0.6495189694070471	[673]	[821,1080,849,901]	9	hSpCas9	negative selection	8298096
68650447	68650470	12	+	27260156	PANC0813	viability	GATAGAAGATTCTTATAGAAAGG	RAP1B	ENSG00000127314	0.5592755515539185	[33]	[74,60,63,37]	8	hSpCas9	negative selection	8355088
68656303	68656326	12	+	27260156	PANC0813	viability	TAGGTTCCAATGATTCTTGTTGG	RAP1B	ENSG00000127314	-0.06910595747476567	[225]	[241,301,186,277]	-1	hSpCas9	negative selection	8355089
68650397	68650420	12	+	27260156	PANC0813	viability	CAGACTGTACAATTTGTTCAAGG	RAP1B	ENSG00000127314	0.36111563178317985	[484]	[792,683,681,769]	6	hSpCas9	negative selection	8355090
68656428	68656451	12	+	27260156	PANC0813	viability	ATCAAAAATAAATGTTAATGAGG	RAP1B	ENSG00000127314	0.08766859310380892	[356]	[449,536,509,293]	1	hSpCas9	negative selection	8419346
68652015	68652038	12	+	27260156	PANC0813	viability	ACAGTGTATGCTTGAAATCTTGG	RAP1B	ENSG00000127314	-0.14914840813230246	[673]	[791,555,948,573]	-2	hSpCas9	negative selection	8419347
68650447	68650470	12	+	27260156	RDES	viability	GATAGAAGATTCTTATAGAAAGG	RAP1B	ENSG00000127314	0.2990391202971363	[33]	[15,33,88,64]	5	hSpCas9	negative selection	8476339
68656303	68656326	12	+	27260156	RDES	viability	TAGGTTCCAATGATTCTTGTTGG	RAP1B	ENSG00000127314	0.24906934637373124	[225]	[288,299,254,397]	4	hSpCas9	negative selection	8476340
68650397	68650420	12	+	27260156	RDES	viability	CAGACTGTACAATTTGTTCAAGG	RAP1B	ENSG00000127314	0.4976317586495218	[484]	[557,750,836,1081]	7	hSpCas9	negative selection	8476341
68656428	68656451	12	+	27260156	RDES	viability	ATCAAAAATAAATGTTAATGAGG	RAP1B	ENSG00000127314	0.16363491568913938	[356]	[370,336,480,706]	2	hSpCas9	negative selection	8540597
68652015	68652038	12	+	27260156	RDES	viability	ACAGTGTATGCTTGAAATCTTGG	RAP1B	ENSG00000127314	0.31083030116220256	[673]	[813,1023,912,1110]	5	hSpCas9	negative selection	8540598
68650447	68650470	12	+	27260156	PC3	viability	GATAGAAGATTCTTATAGAAAGG	RAP1B	ENSG00000127314	-0.4674447542576452	[33]	[2,17,21,64]	-8	hSpCas9	negative selection	8597590
68656303	68656326	12	+	27260156	PC3	viability	TAGGTTCCAATGATTCTTGTTGG	RAP1B	ENSG00000127314	0.3551768482341501	[225]	[175,235,664,245]	7	hSpCas9	negative selection	8597591
68650397	68650420	12	+	27260156	PC3	viability	CAGACTGTACAATTTGTTCAAGG	RAP1B	ENSG00000127314	0.21335230884129622	[484]	[287,517,1254,526]	5	hSpCas9	negative selection	8597592
68656428	68656451	12	+	27260156	PC3	viability	ATCAAAAATAAATGTTAATGAGG	RAP1B	ENSG00000127314	0.015711362277977703	[356]	[263,353,631,293]	0	hSpCas9	negative selection	8661848
68652015	68652038	12	+	27260156	PC3	viability	ACAGTGTATGCTTGAAATCTTGG	RAP1B	ENSG00000127314	-0.05046608186460755	[673]	[377,585,1119,762]	-1	hSpCas9	negative selection	8661849
68650447	68650470	12	+	27260156	PATU8988T	viability	GATAGAAGATTCTTATAGAAAGG	RAP1B	ENSG00000127314	-0.14565890898230283	[33]	[20,19,62,11]	-2	hSpCas9	negative selection	8718841
68656303	68656326	12	+	27260156	PATU8988T	viability	TAGGTTCCAATGATTCTTGTTGG	RAP1B	ENSG00000127314	0.11484946819891118	[225]	[270,161,204,306]	2	hSpCas9	negative selection	8718842
68650397	68650420	12	+	27260156	PATU8988T	viability	CAGACTGTACAATTTGTTCAAGG	RAP1B	ENSG00000127314	0.6242573923382377	[484]	[600,651,604,1052]	8	hSpCas9	negative selection	8718843
68656428	68656451	12	+	27260156	PATU8988T	viability	ATCAAAAATAAATGTTAATGAGG	RAP1B	ENSG00000127314	-0.495042183317209	[356]	[257,172,291,248]	-7	hSpCas9	negative selection	8783099
68652015	68652038	12	+	27260156	PATU8988T	viability	ACAGTGTATGCTTGAAATCTTGG	RAP1B	ENSG00000127314	0.18989089251008184	[673]	[517,660,907,885]	3	hSpCas9	negative selection	8783100
68650447	68650470	12	+	27260156	T47D	viability	GATAGAAGATTCTTATAGAAAGG	RAP1B	ENSG00000127314	0.6182018212027018	[33]	[49,53,46,93]	9	hSpCas9	negative selection	8840092
68656303	68656326	12	+	27260156	T47D	viability	TAGGTTCCAATGATTCTTGTTGG	RAP1B	ENSG00000127314	0.277226381681803	[225]	[324,254,356,344]	6	hSpCas9	negative selection	8840093
68650397	68650420	12	+	27260156	T47D	viability	CAGACTGTACAATTTGTTCAAGG	RAP1B	ENSG00000127314	0.30109124238462004	[484]	[777,654,615,741]	6	hSpCas9	negative selection	8840094
68656428	68656451	12	+	27260156	T47D	viability	ATCAAAAATAAATGTTAATGAGG	RAP1B	ENSG00000127314	-0.2646166545309789	[356]	[408,331,277,368]	-5	hSpCas9	negative selection	8904350
68652015	68652038	12	+	27260156	T47D	viability	ACAGTGTATGCTTGAAATCTTGG	RAP1B	ENSG00000127314	0.10662071605555667	[673]	[815,720,937,917]	2	hSpCas9	negative selection	8904351
68650447	68650470	12	+	27260156	SU8686	viability	GATAGAAGATTCTTATAGAAAGG	RAP1B	ENSG00000127314	0.700930068685667	[33]	[45,32,49,100]	9	hSpCas9	negative selection	8961343
68656303	68656326	12	+	27260156	SU8686	viability	TAGGTTCCAATGATTCTTGTTGG	RAP1B	ENSG00000127314	0.21466116327062346	[225]	[161,251,383,254]	3	hSpCas9	negative selection	8961344
68650397	68650420	12	+	27260156	SU8686	viability	CAGACTGTACAATTTGTTCAAGG	RAP1B	ENSG00000127314	0.5548560624628909	[484]	[632,680,732,800]	8	hSpCas9	negative selection	8961345
68656428	68656451	12	+	27260156	SU8686	viability	ATCAAAAATAAATGTTAATGAGG	RAP1B	ENSG00000127314	0.0539871262785348	[356]	[334,355,324,471]	0	hSpCas9	negative selection	9025601
68652015	68652038	12	+	27260156	SU8686	viability	ACAGTGTATGCTTGAAATCTTGG	RAP1B	ENSG00000127314	-0.20873082316485225	[673]	[468,641,493,729]	-4	hSpCas9	negative selection	9025602
68650447	68650470	12	+	27260156	SKES1	viability	GATAGAAGATTCTTATAGAAAGG	RAP1B	ENSG00000127314	0.07372149806436079	[33]	[76,31,22,17]	1	hSpCas9	negative selection	9082594
68656303	68656326	12	+	27260156	SKES1	viability	TAGGTTCCAATGATTCTTGTTGG	RAP1B	ENSG00000127314	0.5431801703910897	[225]	[460,477,225,198]	9	hSpCas9	negative selection	9082595
68650397	68650420	12	+	27260156	SKES1	viability	CAGACTGTACAATTTGTTCAAGG	RAP1B	ENSG00000127314	0.24143018520494083	[484]	[742,506,644,419]	5	hSpCas9	negative selection	9082596
68656428	68656451	12	+	27260156	SKES1	viability	ATCAAAAATAAATGTTAATGAGG	RAP1B	ENSG00000127314	-0.31138941208585863	[356]	[394,294,203,269]	-6	hSpCas9	negative selection	9146852
68652015	68652038	12	+	27260156	SKES1	viability	ACAGTGTATGCTTGAAATCTTGG	RAP1B	ENSG00000127314	0.18780330721987393	[673]	[779,903,723,676]	4	hSpCas9	negative selection	9146853
68650447	68650470	12	+	27260156	TOV112D	viability	GATAGAAGATTCTTATAGAAAGG	RAP1B	ENSG00000127314	-0.5133584980325772	[33]	[32,22,17,21]	-8	hSpCas9	negative selection	9203845
68656303	68656326	12	+	27260156	TOV112D	viability	TAGGTTCCAATGATTCTTGTTGG	RAP1B	ENSG00000127314	0.16420140757342983	[225]	[321,367,175,183]	3	hSpCas9	negative selection	9203846
68650397	68650420	12	+	27260156	TOV112D	viability	CAGACTGTACAATTTGTTCAAGG	RAP1B	ENSG00000127314	0.07397348584873074	[484]	[446,757,539,358]	1	hSpCas9	negative selection	9203847
68656428	68656451	12	+	27260156	TOV112D	viability	ATCAAAAATAAATGTTAATGAGG	RAP1B	ENSG00000127314	0.26363073395722936	[356]	[397,696,308,376]	5	hSpCas9	negative selection	9268103
68652015	68652038	12	+	27260156	TOV112D	viability	ACAGTGTATGCTTGAAATCTTGG	RAP1B	ENSG00000127314	-0.3339138847270864	[673]	[528,579,551,491]	-6	hSpCas9	negative selection	9268104
68650447	68650470	12	+	27260156	TC71	viability	GATAGAAGATTCTTATAGAAAGG	RAP1B	ENSG00000127314	0.103051246342726	[33]	[49,26,62,13]	2	hSpCas9	negative selection	9325096
68656303	68656326	12	+	27260156	TC71	viability	TAGGTTCCAATGATTCTTGTTGG	RAP1B	ENSG00000127314	0.37117221233505526	[225]	[279,275,290,413]	8	hSpCas9	negative selection	9325097
68650397	68650420	12	+	27260156	TC71	viability	CAGACTGTACAATTTGTTCAAGG	RAP1B	ENSG00000127314	0.120764103182772	[484]	[519,690,414,645]	3	hSpCas9	negative selection	9325098
68656428	68656451	12	+	27260156	TC71	viability	ATCAAAAATAAATGTTAATGAGG	RAP1B	ENSG00000127314	-0.1815986256648237	[356]	[390,259,306,394]	-5	hSpCas9	negative selection	9389354
68652015	68652038	12	+	27260156	TC71	viability	ACAGTGTATGCTTGAAATCTTGG	RAP1B	ENSG00000127314	-0.04189702456813571	[673]	[557,777,711,765]	-1	hSpCas9	negative selection	9389355
68650447	68650470	12	+	27260156	TC32	viability	GATAGAAGATTCTTATAGAAAGG	RAP1B	ENSG00000127314	-0.4774685931101734	[33]	[20,18,10,39]	-7	hSpCas9	negative selection	9446347
68656303	68656326	12	+	27260156	TC32	viability	TAGGTTCCAATGATTCTTGTTGG	RAP1B	ENSG00000127314	0.5620244300532913	[225]	[267,337,365,263]	8	hSpCas9	negative selection	9446348
68650397	68650420	12	+	27260156	TC32	viability	CAGACTGTACAATTTGTTCAAGG	RAP1B	ENSG00000127314	0.4398548065680751	[484]	[687,353,839,688]	7	hSpCas9	negative selection	9446349
68656428	68656451	12	+	27260156	TC32	viability	ATCAAAAATAAATGTTAATGAGG	RAP1B	ENSG00000127314	-0.08078397237081725	[356]	[334,201,350,414]	-1	hSpCas9	negative selection	9510605
68652015	68652038	12	+	27260156	TC32	viability	ACAGTGTATGCTTGAAATCTTGG	RAP1B	ENSG00000127314	0.06977312105104394	[673]	[714,393,877,772]	1	hSpCas9	negative selection	9510606
68648760	68648783	12	+	28162770	P31FUJ	viability	AGGCGTTGGAAAGTCTGCTTTGG	RAP1B	ENSG00000127314	0.7597803240231383	[194]	[387]	8	hSpCas9	negative selection	10222182
68652030	68652053	12	+	28162770	P31FUJ	viability	AATCTTGGATACTGCAGGAACGG	RAP1B	ENSG00000127314	-0.2829588793865375	[438]	[423]	-3	hSpCas9	negative selection	10222183
68648737	68648760	12	+	28162770	P31FUJ	viability	AAGCTAGTCGTTCTTGGCTCAGG	RAP1B	ENSG00000127314	-0.13535386429855978	[414]	[443]	-1	hSpCas9	negative selection	10222184
68648746	68648769	12	+	28162770	P31FUJ	viability	GTTCTTGGCTCAGGAGGCGTTGG	RAP1B	ENSG00000127314	-2.0170735133589415	[61]	[17]	-8	hSpCas9	negative selection	10222185
68656344	68656367	12	+	28162770	P31FUJ	viability	AGATGAAAGAGTTGTAGGGAAGG	RAP1B	ENSG00000127314	-0.07314553842589344	[93]	[104]	0	hSpCas9	negative selection	10222186
68654110	68654133	12	+	28162770	P31FUJ	viability	AGGAGCAATTTACAGCAATGAGG	RAP1B	ENSG00000127314	0.5455660887623901	[315]	[541]	6	hSpCas9	negative selection	10222187
68654176	68654199	12	-	28162770	P31FUJ	viability	AAATGTGGACTGTGCTGTGATGG	RAP1B	ENSG00000127314	0.05470829341562217	[262]	[320]	0	hSpCas9	negative selection	10222188
68652025	68652048	12	+	28162770	P31FUJ	viability	CTTGAAATCTTGGATACTGCAGG	RAP1B	ENSG00000127314	-0.16765817909486846	[432]	[452]	-2	hSpCas9	negative selection	10222189
68656351	68656374	12	+	28162770	P31FUJ	viability	AGAGTTGTAGGGAAGGAACAAGG	RAP1B	ENSG00000127314	-0.2905177022706661	[152]	[146]	-3	hSpCas9	negative selection	10222190
68657140	68657163	12	-	28162770	P31FUJ	viability	TTGCGAGCCTTCCCAGGCACTGG	RAP1B	ENSG00000127314	0.4128717102958217	[697]	[1091]	4	hSpCas9	negative selection	10222191
68648760	68648783	12	+	28162770	TF1	viability	AGGCGTTGGAAAGTCTGCTTTGG	RAP1B	ENSG00000127314	NaN	[NaN]	[346]	1	hSpCas9	negative selection	10391548
68652030	68652053	12	+	28162770	TF1	viability	AATCTTGGATACTGCAGGAACGG	RAP1B	ENSG00000127314	NaN	[NaN]	[521]	1	hSpCas9	negative selection	10391549
68648737	68648760	12	+	28162770	TF1	viability	AAGCTAGTCGTTCTTGGCTCAGG	RAP1B	ENSG00000127314	NaN	[NaN]	[318]	1	hSpCas9	negative selection	10391550
68648746	68648769	12	+	28162770	TF1	viability	GTTCTTGGCTCAGGAGGCGTTGG	RAP1B	ENSG00000127314	NaN	[NaN]	[5]	1	hSpCas9	negative selection	10391551
68656344	68656367	12	+	28162770	TF1	viability	AGATGAAAGAGTTGTAGGGAAGG	RAP1B	ENSG00000127314	NaN	[NaN]	[148]	1	hSpCas9	negative selection	10391552
68654110	68654133	12	+	28162770	TF1	viability	AGGAGCAATTTACAGCAATGAGG	RAP1B	ENSG00000127314	NaN	[NaN]	[790]	1	hSpCas9	negative selection	10391553
68654176	68654199	12	-	28162770	TF1	viability	AAATGTGGACTGTGCTGTGATGG	RAP1B	ENSG00000127314	NaN	[NaN]	[199]	1	hSpCas9	negative selection	10391554
68652025	68652048	12	+	28162770	TF1	viability	CTTGAAATCTTGGATACTGCAGG	RAP1B	ENSG00000127314	NaN	[NaN]	[287]	1	hSpCas9	negative selection	10391555
68656351	68656374	12	+	28162770	TF1	viability	AGAGTTGTAGGGAAGGAACAAGG	RAP1B	ENSG00000127314	NaN	[NaN]	[308]	1	hSpCas9	negative selection	10391556
68657140	68657163	12	-	28162770	TF1	viability	TTGCGAGCCTTCCCAGGCACTGG	RAP1B	ENSG00000127314	NaN	[NaN]	[744]	1	hSpCas9	negative selection	10391557
68648760	68648783	12	+	28162770	SKM1	viability	AGGCGTTGGAAAGTCTGCTTTGG	RAP1B	ENSG00000127314	0.9380475092572417	[92]	[314]	8	hSpCas9	negative selection	10560914
68652030	68652053	12	+	28162770	SKM1	viability	AATCTTGGATACTGCAGGAACGG	RAP1B	ENSG00000127314	-0.28696442263253163	[146]	[212]	-2	hSpCas9	negative selection	10560915
68648737	68648760	12	+	28162770	SKM1	viability	AAGCTAGTCGTTCTTGGCTCAGG	RAP1B	ENSG00000127314	0.8837129621597609	[83]	[273]	8	hSpCas9	negative selection	10560916
68648746	68648769	12	+	28162770	SKM1	viability	GTTCTTGGCTCAGGAGGCGTTGG	RAP1B	ENSG00000127314	2.3612201260337646	[11]	[108]	9	hSpCas9	negative selection	10560917
68656344	68656367	12	+	28162770	SKM1	viability	AGATGAAAGAGTTGTAGGGAAGG	RAP1B	ENSG00000127314	0.9782287896022168	[28]	[100]	8	hSpCas9	negative selection	10560918
68654110	68654133	12	+	28162770	SKM1	viability	AGGAGCAATTTACAGCAATGAGG	RAP1B	ENSG00000127314	0.9505878058749221	[95]	[327]	8	hSpCas9	negative selection	10560919
68654176	68654199	12	-	28162770	SKM1	viability	AAATGTGGACTGTGCTGTGATGG	RAP1B	ENSG00000127314	0.476339576547741	[73]	[181]	4	hSpCas9	negative selection	10560920
68652025	68652048	12	+	28162770	SKM1	viability	CTTGAAATCTTGGATACTGCAGG	RAP1B	ENSG00000127314	-0.5265458144958342	[65]	[80]	-4	hSpCas9	negative selection	10560921
68656351	68656374	12	+	28162770	SKM1	viability	AGAGTTGTAGGGAAGGAACAAGG	RAP1B	ENSG00000127314	-0.11305048002539601	[51]	[84]	-1	hSpCas9	negative selection	10560922
68657140	68657163	12	-	28162770	SKM1	viability	TTGCGAGCCTTCCCAGGCACTGG	RAP1B	ENSG00000127314	1.1214147736116271	[142]	[549]	9	hSpCas9	negative selection	10560923
68648760	68648783	12	+	28162770	SKM1	viability	AGGCGTTGGAAAGTCTGCTTTGG	RAP1B	ENSG00000127314	0.9380475092572417	[92]	[314]	8	hSpCas9	negative selection	10730280
68652030	68652053	12	+	28162770	SKM1	viability	AATCTTGGATACTGCAGGAACGG	RAP1B	ENSG00000127314	-0.28696442263253163	[146]	[212]	-2	hSpCas9	negative selection	10730281
68648737	68648760	12	+	28162770	SKM1	viability	AAGCTAGTCGTTCTTGGCTCAGG	RAP1B	ENSG00000127314	0.8837129621597609	[83]	[273]	8	hSpCas9	negative selection	10730282
68648746	68648769	12	+	28162770	SKM1	viability	GTTCTTGGCTCAGGAGGCGTTGG	RAP1B	ENSG00000127314	2.3612201260337646	[11]	[108]	9	hSpCas9	negative selection	10730283
68656344	68656367	12	+	28162770	SKM1	viability	AGATGAAAGAGTTGTAGGGAAGG	RAP1B	ENSG00000127314	0.9782287896022168	[28]	[100]	8	hSpCas9	negative selection	10730284
68654110	68654133	12	+	28162770	SKM1	viability	AGGAGCAATTTACAGCAATGAGG	RAP1B	ENSG00000127314	0.9505878058749221	[95]	[327]	8	hSpCas9	negative selection	10730285
68654176	68654199	12	-	28162770	SKM1	viability	AAATGTGGACTGTGCTGTGATGG	RAP1B	ENSG00000127314	0.476339576547741	[73]	[181]	4	hSpCas9	negative selection	10730286
68652025	68652048	12	+	28162770	SKM1	viability	CTTGAAATCTTGGATACTGCAGG	RAP1B	ENSG00000127314	-0.5265458144958342	[65]	[80]	-4	hSpCas9	negative selection	10730287
68656351	68656374	12	+	28162770	SKM1	viability	AGAGTTGTAGGGAAGGAACAAGG	RAP1B	ENSG00000127314	-0.11305048002539601	[51]	[84]	-1	hSpCas9	negative selection	10730288
68657140	68657163	12	-	28162770	SKM1	viability	TTGCGAGCCTTCCCAGGCACTGG	RAP1B	ENSG00000127314	1.1214147736116271	[142]	[549]	9	hSpCas9	negative selection	10730289
68648760	68648783	12	+	28162770	PL21	viability	AGGCGTTGGAAAGTCTGCTTTGG	RAP1B	ENSG00000127314	0.9381695355506363	[270]	[225]	7	hSpCas9	negative selection	10899646
68652030	68652053	12	+	28162770	PL21	viability	AATCTTGGATACTGCAGGAACGG	RAP1B	ENSG00000127314	-0.046556054529725666	[438]	[184]	0	hSpCas9	negative selection	10899647
68648737	68648760	12	+	28162770	PL21	viability	AAGCTAGTCGTTCTTGGCTCAGG	RAP1B	ENSG00000127314	0.055516051409867595	[324]	[146]	0	hSpCas9	negative selection	10899648
68648746	68648769	12	+	28162770	PL21	viability	GTTCTTGGCTCAGGAGGCGTTGG	RAP1B	ENSG00000127314	0.20013961448932038	[27]	[13]	1	hSpCas9	negative selection	10899649
68656344	68656367	12	+	28162770	PL21	viability	AGATGAAAGAGTTGTAGGGAAGG	RAP1B	ENSG00000127314	-0.15940277219782006	[135]	[52]	-1	hSpCas9	negative selection	10899650
68654110	68654133	12	+	28162770	PL21	viability	AGGAGCAATTTACAGCAATGAGG	RAP1B	ENSG00000127314	0.16896371860614257	[420]	[205]	1	hSpCas9	negative selection	10899651
68654176	68654199	12	-	28162770	PL21	viability	AAATGTGGACTGTGCTGTGATGG	RAP1B	ENSG00000127314	0.1631454070071185	[157]	[76]	1	hSpCas9	negative selection	10899652
68652025	68652048	12	+	28162770	PL21	viability	CTTGAAATCTTGGATACTGCAGG	RAP1B	ENSG00000127314	0.27597102744896607	[314]	[165]	2	hSpCas9	negative selection	10899653
68656351	68656374	12	+	28162770	PL21	viability	AGAGTTGTAGGGAAGGAACAAGG	RAP1B	ENSG00000127314	-0.23181126772587007	[142]	[52]	-2	hSpCas9	negative selection	10899654
68657140	68657163	12	-	28162770	PL21	viability	TTGCGAGCCTTCCCAGGCACTGG	RAP1B	ENSG00000127314	0.4507657165547121	[505]	[300]	4	hSpCas9	negative selection	10899655
68648760	68648783	12	+	28162770	P31FUJ	viability	AGGCGTTGGAAAGTCTGCTTTGG	RAP1B	ENSG00000127314	0.7597803240231383	[194]	[387]	8	hSpCas9	negative selection	11069012
68652030	68652053	12	+	28162770	P31FUJ	viability	AATCTTGGATACTGCAGGAACGG	RAP1B	ENSG00000127314	-0.2829588793865375	[438]	[423]	-3	hSpCas9	negative selection	11069013
68648737	68648760	12	+	28162770	P31FUJ	viability	AAGCTAGTCGTTCTTGGCTCAGG	RAP1B	ENSG00000127314	-0.13535386429855978	[414]	[443]	-1	hSpCas9	negative selection	11069014
68648746	68648769	12	+	28162770	P31FUJ	viability	GTTCTTGGCTCAGGAGGCGTTGG	RAP1B	ENSG00000127314	-2.0170735133589415	[61]	[17]	-8	hSpCas9	negative selection	11069015
68656344	68656367	12	+	28162770	P31FUJ	viability	AGATGAAAGAGTTGTAGGGAAGG	RAP1B	ENSG00000127314	-0.07314553842589344	[93]	[104]	0	hSpCas9	negative selection	11069016
68654110	68654133	12	+	28162770	P31FUJ	viability	AGGAGCAATTTACAGCAATGAGG	RAP1B	ENSG00000127314	0.5455660887623901	[315]	[541]	6	hSpCas9	negative selection	11069017
68654176	68654199	12	-	28162770	P31FUJ	viability	AAATGTGGACTGTGCTGTGATGG	RAP1B	ENSG00000127314	0.05470829341562217	[262]	[320]	0	hSpCas9	negative selection	11069018
68652025	68652048	12	+	28162770	P31FUJ	viability	CTTGAAATCTTGGATACTGCAGG	RAP1B	ENSG00000127314	-0.16765817909486846	[432]	[452]	-2	hSpCas9	negative selection	11069019
68656351	68656374	12	+	28162770	P31FUJ	viability	AGAGTTGTAGGGAAGGAACAAGG	RAP1B	ENSG00000127314	-0.2905177022706661	[152]	[146]	-3	hSpCas9	negative selection	11069020
68657140	68657163	12	-	28162770	P31FUJ	viability	TTGCGAGCCTTCCCAGGCACTGG	RAP1B	ENSG00000127314	0.4128717102958217	[697]	[1091]	4	hSpCas9	negative selection	11069021
68648760	68648783	12	+	28162770	OCIAML5	viability	AGGCGTTGGAAAGTCTGCTTTGG	RAP1B	ENSG00000127314	1.3023620942551473	[103]	[462]	9	hSpCas9	negative selection	11238378
68652030	68652053	12	+	28162770	OCIAML5	viability	AATCTTGGATACTGCAGGAACGG	RAP1B	ENSG00000127314	0.17503865929860085	[289]	[590]	1	hSpCas9	negative selection	11238379
68648737	68648760	12	+	28162770	OCIAML5	viability	AAGCTAGTCGTTCTTGGCTCAGG	RAP1B	ENSG00000127314	0.7571945259805561	[156]	[478]	6	hSpCas9	negative selection	11238380
68648746	68648769	12	+	28162770	OCIAML5	viability	GTTCTTGGCTCAGGAGGCGTTGG	RAP1B	ENSG00000127314	-4.437029071585153	[11]	[0]	-9	hSpCas9	negative selection	11238381
68656344	68656367	12	+	28162770	OCIAML5	viability	AGATGAAAGAGTTGTAGGGAAGG	RAP1B	ENSG00000127314	0.15681158048245603	[80]	[162]	1	hSpCas9	negative selection	11238382
68654110	68654133	12	+	28162770	OCIAML5	viability	AGGAGCAATTTACAGCAATGAGG	RAP1B	ENSG00000127314	0.9910004479130101	[227]	[817]	8	hSpCas9	negative selection	11238383
68654176	68654199	12	-	28162770	OCIAML5	viability	AAATGTGGACTGTGCTGTGATGG	RAP1B	ENSG00000127314	0.3716054026990234	[160]	[375]	3	hSpCas9	negative selection	11238384
68652025	68652048	12	+	28162770	OCIAML5	viability	CTTGAAATCTTGGATACTGCAGG	RAP1B	ENSG00000127314	0.5605961212269435	[227]	[606]	5	hSpCas9	negative selection	11238385
68656351	68656374	12	+	28162770	OCIAML5	viability	AGAGTTGTAGGGAAGGAACAAGG	RAP1B	ENSG00000127314	-0.0887668288843283	[75]	[128]	0	hSpCas9	negative selection	11238386
68657140	68657163	12	-	28162770	OCIAML5	viability	TTGCGAGCCTTCCCAGGCACTGG	RAP1B	ENSG00000127314	0.057518133913784464	[320]	[602]	0	hSpCas9	negative selection	11238387
68648760	68648783	12	+	28162770	EOL1	viability	AGGCGTTGGAAAGTCTGCTTTGG	RAP1B	ENSG00000127314	0.3560562805282792	[478]	[322]	3	hSpCas9	negative selection	11407744
68652030	68652053	12	+	28162770	EOL1	viability	AATCTTGGATACTGCAGGAACGG	RAP1B	ENSG00000127314	0.35450469068511736	[480]	[323]	3	hSpCas9	negative selection	11407745
68648737	68648760	12	+	28162770	EOL1	viability	AAGCTAGTCGTTCTTGGCTCAGG	RAP1B	ENSG00000127314	1.230613480638929	[566]	[700]	8	hSpCas9	negative selection	11407746
68648746	68648769	12	+	28162770	EOL1	viability	GTTCTTGGCTCAGGAGGCGTTGG	RAP1B	ENSG00000127314	-1.1769902548915279	[102]	[23]	-7	hSpCas9	negative selection	11407747
68656344	68656367	12	+	28162770	EOL1	viability	AGATGAAAGAGTTGTAGGGAAGG	RAP1B	ENSG00000127314	0.5438034498455686	[193]	[148]	5	hSpCas9	negative selection	11407748
68654110	68654133	12	+	28162770	EOL1	viability	AGGAGCAATTTACAGCAATGAGG	RAP1B	ENSG00000127314	1.395177596812696	[559]	[775]	9	hSpCas9	negative selection	11407749
68654176	68654199	12	-	28162770	EOL1	viability	AAATGTGGACTGTGCTGTGATGG	RAP1B	ENSG00000127314	0.33701591123724506	[280]	[186]	3	hSpCas9	negative selection	11407750
68652025	68652048	12	+	28162770	EOL1	viability	CTTGAAATCTTGGATACTGCAGG	RAP1B	ENSG00000127314	0.456330234432516	[349]	[252]	4	hSpCas9	negative selection	11407751
68656351	68656374	12	+	28162770	EOL1	viability	AGAGTTGTAGGGAAGGAACAAGG	RAP1B	ENSG00000127314	-1.4199817522539604	[192]	[37]	-7	hSpCas9	negative selection	11407752
68657140	68657163	12	-	28162770	EOL1	viability	TTGCGAGCCTTCCCAGGCACTGG	RAP1B	ENSG00000127314	-0.6467212496880005	[733]	[246]	-5	hSpCas9	negative selection	11407753
68648760	68648783	12	+	28162770	MOLM13	viability	AGGCGTTGGAAAGTCTGCTTTGG	RAP1B	ENSG00000127314	0.4349747590718438	[398]	[389]	3	hSpCas9	negative selection	11577110
68652030	68652053	12	+	28162770	MOLM13	viability	AATCTTGGATACTGCAGGAACGG	RAP1B	ENSG00000127314	0.8462294698072155	[646]	[840]	6	hSpCas9	negative selection	11577111
68648737	68648760	12	+	28162770	MOLM13	viability	AAGCTAGTCGTTCTTGGCTCAGG	RAP1B	ENSG00000127314	1.1722670492105056	[393]	[641]	8	hSpCas9	negative selection	11577112
68648746	68648769	12	+	28162770	MOLM13	viability	GTTCTTGGCTCAGGAGGCGTTGG	RAP1B	ENSG00000127314	-0.42288154870066297	[88]	[47]	-3	hSpCas9	negative selection	11577113
68656344	68656367	12	+	28162770	MOLM13	viability	AGATGAAAGAGTTGTAGGGAAGG	RAP1B	ENSG00000127314	0.14596128665721664	[194]	[155]	1	hSpCas9	negative selection	11577114
68654110	68654133	12	+	28162770	MOLM13	viability	AGGAGCAATTTACAGCAATGAGG	RAP1B	ENSG00000127314	0.9283373405133691	[515]	[709]	7	hSpCas9	negative selection	11577115
68654176	68654199	12	-	28162770	MOLM13	viability	AAATGTGGACTGTGCTGTGATGG	RAP1B	ENSG00000127314	1.0214389296342734	[324]	[476]	7	hSpCas9	negative selection	11577116
68652025	68652048	12	+	28162770	MOLM13	viability	CTTGAAATCTTGGATACTGCAGG	RAP1B	ENSG00000127314	1.0414471189934855	[507]	[755]	7	hSpCas9	negative selection	11577117
68656351	68656374	12	+	28162770	MOLM13	viability	AGAGTTGTAGGGAAGGAACAAGG	RAP1B	ENSG00000127314	0.012588012052007713	[217]	[158]	0	hSpCas9	negative selection	11577118
68657140	68657163	12	-	28162770	MOLM13	viability	TTGCGAGCCTTCCCAGGCACTGG	RAP1B	ENSG00000127314	-0.9711390643007665	[666]	[245]	-5	hSpCas9	negative selection	11577119
68648760	68648783	12	+	28162770	HEL	viability	AGGCGTTGGAAAGTCTGCTTTGG	RAP1B	ENSG00000127314	0.2619641572380582	[318]	[244]	2	hSpCas9	negative selection	11746476
68652030	68652053	12	+	28162770	HEL	viability	AATCTTGGATACTGCAGGAACGG	RAP1B	ENSG00000127314	-0.9363827901317391	[492]	[164]	-5	hSpCas9	negative selection	11746477
68648737	68648760	12	+	28162770	HEL	viability	AAGCTAGTCGTTCTTGGCTCAGG	RAP1B	ENSG00000127314	0.5838451429467885	[374]	[359]	5	hSpCas9	negative selection	11746478
68648746	68648769	12	+	28162770	HEL	viability	GTTCTTGGCTCAGGAGGCGTTGG	RAP1B	ENSG00000127314	-5.8329945989660406	[88]	[0]	-9	hSpCas9	negative selection	11746479
68656344	68656367	12	+	28162770	HEL	viability	AGATGAAAGAGTTGTAGGGAAGG	RAP1B	ENSG00000127314	-0.5195325968985202	[140]	[62]	-4	hSpCas9	negative selection	11746480
68654110	68654133	12	+	28162770	HEL	viability	AGGAGCAATTTACAGCAATGAGG	RAP1B	ENSG00000127314	1.3843939428501941	[429]	[718]	9	hSpCas9	negative selection	11746481
68654176	68654199	12	-	28162770	HEL	viability	AAATGTGGACTGTGCTGTGATGG	RAP1B	ENSG00000127314	0.9667118528727437	[281]	[352]	8	hSpCas9	negative selection	11746482
68652025	68652048	12	+	28162770	HEL	viability	CTTGAAATCTTGGATACTGCAGG	RAP1B	ENSG00000127314	0.891482580283757	[371]	[441]	7	hSpCas9	negative selection	11746483
68656351	68656374	12	+	28162770	HEL	viability	AGAGTTGTAGGGAAGGAACAAGG	RAP1B	ENSG00000127314	-0.41866171266378627	[143]	[68]	-3	hSpCas9	negative selection	11746484
68657140	68657163	12	-	28162770	HEL	viability	TTGCGAGCCTTCCCAGGCACTGG	RAP1B	ENSG00000127314	-0.8960340357007316	[583]	[200]	-5	hSpCas9	negative selection	11746485
68648760	68648783	12	+	28162770	MV411	viability	AGGCGTTGGAAAGTCTGCTTTGG	RAP1B	ENSG00000127314	0.978005373750831	[225]	[374]	8	hSpCas9	negative selection	11915842
68652030	68652053	12	+	28162770	MV411	viability	AATCTTGGATACTGCAGGAACGG	RAP1B	ENSG00000127314	0.3014151718416004	[340]	[353]	2	hSpCas9	negative selection	11915843
68648737	68648760	12	+	28162770	MV411	viability	AAGCTAGTCGTTCTTGGCTCAGG	RAP1B	ENSG00000127314	0.8558590243279204	[304]	[464]	7	hSpCas9	negative selection	11915844
68648746	68648769	12	+	28162770	MV411	viability	GTTCTTGGCTCAGGAGGCGTTGG	RAP1B	ENSG00000127314	-1.716036573192111	[38]	[9]	-8	hSpCas9	negative selection	11915845
68656344	68656367	12	+	28162770	MV411	viability	AGATGAAAGAGTTGTAGGGAAGG	RAP1B	ENSG00000127314	0.19029364367916646	[102]	[98]	1	hSpCas9	negative selection	11915846
68654110	68654133	12	+	28162770	MV411	viability	AGGAGCAATTTACAGCAATGAGG	RAP1B	ENSG00000127314	0.8018656833558193	[381]	[560]	7	hSpCas9	negative selection	11915847
68654176	68654199	12	-	28162770	MV411	viability	AAATGTGGACTGTGCTGTGATGG	RAP1B	ENSG00000127314	-0.2844901876165127	[226]	[156]	-2	hSpCas9	negative selection	11915848
68652025	68652048	12	+	28162770	MV411	viability	CTTGAAATCTTGGATACTGCAGG	RAP1B	ENSG00000127314	0.5031393103821	[262]	[313]	4	hSpCas9	negative selection	11915849
68656351	68656374	12	+	28162770	MV411	viability	AGAGTTGTAGGGAAGGAACAAGG	RAP1B	ENSG00000127314	-0.23289140874778747	[112]	[80]	-2	hSpCas9	negative selection	11915850
68657140	68657163	12	-	28162770	MV411	viability	TTGCGAGCCTTCCCAGGCACTGG	RAP1B	ENSG00000127314	0.04960478281738756	[397]	[346]	0	hSpCas9	negative selection	11915851
68648760	68648783	12	+	28162770	MONOMAC1	viability	AGGCGTTGGAAAGTCTGCTTTGG	RAP1B	ENSG00000127314	0.5698302328205146	[190]	[324]	5	hSpCas9	negative selection	12085208
68652030	68652053	12	+	28162770	MONOMAC1	viability	AATCTTGGATACTGCAGGAACGG	RAP1B	ENSG00000127314	1.5778685486808726	[333]	[1142]	9	hSpCas9	negative selection	12085209
68648737	68648760	12	+	28162770	MONOMAC1	viability	AAGCTAGTCGTTCTTGGCTCAGG	RAP1B	ENSG00000127314	0.09841903646661743	[241]	[296]	1	hSpCas9	negative selection	12085210
68648746	68648769	12	+	28162770	MONOMAC1	viability	GTTCTTGGCTCAGGAGGCGTTGG	RAP1B	ENSG00000127314	-0.7589157346676687	[30]	[20]	-6	hSpCas9	negative selection	12085211
68656344	68656367	12	+	28162770	MONOMAC1	viability	AGATGAAAGAGTTGTAGGGAAGG	RAP1B	ENSG00000127314	-0.16600995143892922	[91]	[93]	-1	hSpCas9	negative selection	12085212
68654110	68654133	12	+	28162770	MONOMAC1	viability	AGGAGCAATTTACAGCAATGAGG	RAP1B	ENSG00000127314	2.232167984145884	[284]	[1534]	9	hSpCas9	negative selection	12085213
68654176	68654199	12	-	28162770	MONOMAC1	viability	AAATGTGGACTGTGCTGTGATGG	RAP1B	ENSG00000127314	-0.26742617495095156	[146]	[139]	-2	hSpCas9	negative selection	12085214
68652025	68652048	12	+	28162770	MONOMAC1	viability	CTTGAAATCTTGGATACTGCAGG	RAP1B	ENSG00000127314	0.330374631099444	[178]	[257]	3	hSpCas9	negative selection	12085215
68656351	68656374	12	+	28162770	MONOMAC1	viability	AGAGTTGTAGGGAAGGAACAAGG	RAP1B	ENSG00000127314	0.34248268290043526	[85]	[124]	3	hSpCas9	negative selection	12085216
68657140	68657163	12	-	28162770	MONOMAC1	viability	TTGCGAGCCTTCCCAGGCACTGG	RAP1B	ENSG00000127314	0.358581692079458	[297]	[437]	3	hSpCas9	negative selection	12085217
68648760	68648783	12	+	28162770	OCIAML2	viability	AGGCGTTGGAAAGTCTGCTTTGG	RAP1B	ENSG00000127314	-0.4486035189121623	[64]	[263]	-4	hSpCas9	negative selection	12254574
68652030	68652053	12	+	28162770	OCIAML2	viability	AATCTTGGATACTGCAGGAACGG	RAP1B	ENSG00000127314	-0.4333702066730789	[85]	[352]	-3	hSpCas9	negative selection	12254575
68648737	68648760	12	+	28162770	OCIAML2	viability	AAGCTAGTCGTTCTTGGCTCAGG	RAP1B	ENSG00000127314	0.4068169924738755	[65]	[484]	4	hSpCas9	negative selection	12254576
68648746	68648769	12	+	28162770	OCIAML2	viability	GTTCTTGGCTCAGGAGGCGTTGG	RAP1B	ENSG00000127314	-1.622632918687211	[9]	[17]	-7	hSpCas9	negative selection	12254577
68656344	68656367	12	+	28162770	OCIAML2	viability	AGATGAAAGAGTTGTAGGGAAGG	RAP1B	ENSG00000127314	-0.7233958956221279	[27]	[93]	-5	hSpCas9	negative selection	12254578
68654110	68654133	12	+	28162770	OCIAML2	viability	AGGAGCAATTTACAGCAATGAGG	RAP1B	ENSG00000127314	0.3278651198952145	[69]	[486]	3	hSpCas9	negative selection	12254579
68654176	68654199	12	-	28162770	OCIAML2	viability	AAATGTGGACTGTGCTGTGATGG	RAP1B	ENSG00000127314	-0.20759541940836734	[49]	[239]	-2	hSpCas9	negative selection	12254580
68652025	68652048	12	+	28162770	OCIAML2	viability	CTTGAAATCTTGGATACTGCAGG	RAP1B	ENSG00000127314	0.21968567562522356	[54]	[354]	2	hSpCas9	negative selection	12254581
68656351	68656374	12	+	28162770	OCIAML2	viability	AGAGTTGTAGGGAAGGAACAAGG	RAP1B	ENSG00000127314	-0.09211820198843142	[34]	[181]	-1	hSpCas9	negative selection	12254582
68657140	68657163	12	-	28162770	OCIAML2	viability	TTGCGAGCCTTCCCAGGCACTGG	RAP1B	ENSG00000127314	-0.2734379580308559	[98]	[453]	-2	hSpCas9	negative selection	12254583
68648760	68648783	12	+	28162770	OCIAML3	viability	AGGCGTTGGAAAGTCTGCTTTGG	RAP1B	ENSG00000127314	0.5597976957548723	[59]	[266]	5	hSpCas9	negative selection	12423940
68652030	68652053	12	+	28162770	OCIAML3	viability	AATCTTGGATACTGCAGGAACGG	RAP1B	ENSG00000127314	0.1920023793350858	[106]	[368]	1	hSpCas9	negative selection	12423941
68648737	68648760	12	+	28162770	OCIAML3	viability	AAGCTAGTCGTTCTTGGCTCAGG	RAP1B	ENSG00000127314	0.2791623374403541	[100]	[369]	2	hSpCas9	negative selection	12423942
68648746	68648769	12	+	28162770	OCIAML3	viability	GTTCTTGGCTCAGGAGGCGTTGG	RAP1B	ENSG00000127314	-2.664396968215561	[20]	[9]	-9	hSpCas9	negative selection	12423943
68656344	68656367	12	+	28162770	OCIAML3	viability	AGATGAAAGAGTTGTAGGGAAGG	RAP1B	ENSG00000127314	0.19026366862039978	[26]	[92]	1	hSpCas9	negative selection	12423944
68654110	68654133	12	+	28162770	OCIAML3	viability	AGGAGCAATTTACAGCAATGAGG	RAP1B	ENSG00000127314	-0.14654866335294192	[98]	[269]	-1	hSpCas9	negative selection	12423945
68654176	68654199	12	-	28162770	OCIAML3	viability	AAATGTGGACTGTGCTGTGATGG	RAP1B	ENSG00000127314	-0.37161521898771527	[53]	[125]	-3	hSpCas9	negative selection	12423946
68652025	68652048	12	+	28162770	OCIAML3	viability	CTTGAAATCTTGGATACTGCAGG	RAP1B	ENSG00000127314	1.1567637533670736	[77]	[524]	8	hSpCas9	negative selection	12423947
68656351	68656374	12	+	28162770	OCIAML3	viability	AGAGTTGTAGGGAAGGAACAAGG	RAP1B	ENSG00000127314	-0.5008982359326815	[29]	[63]	-4	hSpCas9	negative selection	12423948
68657140	68657163	12	-	28162770	OCIAML3	viability	TTGCGAGCCTTCCCAGGCACTGG	RAP1B	ENSG00000127314	0.28763016335244385	[145]	[537]	2	hSpCas9	negative selection	12423949