| 144517620 | 144517643 | 8 | - | 24336569 | HL60 | viability | TTTACAGGACGACGTGGAGGCGG | RECQL4 | ENSG00000160957 | -0.7413052686644475 | [518] | [656] | -6 | hSpCas9 | negative selection | 2289132 | 144517626 | 144517649 | 8 | - | 24336569 | HL60 | viability | GTTCCCTTTACAGGACGACGTGG | RECQL4 | ENSG00000160957 | -0.26768290941185924 | [383] | [674] | -2 | hSpCas9 | negative selection | 2289133 | 144517687 | 144517710 | 8 | + | 24336569 | HL60 | viability | TGGGCAGCCCGCACCTGGCTCGG | RECQL4 | ENSG00000160957 | 0.8186373293169832 | [283] | [1059] | 6 | hSpCas9 | negative selection | 2289134 | 144517716 | 144517739 | 8 | - | 24336569 | HL60 | viability | GCGCGTTCCGACGGCAGCGCGGG | RECQL4 | ENSG00000160957 | -0.3281490182841813 | [543] | [916] | -3 | hSpCas9 | negative selection | 2289135 | 144517725 | 144517748 | 8 | - | 24336569 | HL60 | viability | CGTGGGAGCGCGCGTTCCGACGG | RECQL4 | ENSG00000160957 | -0.49495613104983704 | [310] | [466] | -4 | hSpCas9 | negative selection | 2289136 | 144517742 | 144517765 | 8 | - | 24336569 | HL60 | viability | GCGGGAGCGGCTGCAGGCGTGGG | RECQL4 | ENSG00000160957 | -1.0174000011303093 | [946] | [989] | -7 | hSpCas9 | negative selection | 2289137 | 144517748 | 144517771 | 8 | - | 24336569 | HL60 | viability | GGACGTGCGGGAGCGGCTGCAGG | RECQL4 | ENSG00000160957 | 0.2895295533408173 | [1109] | [2870] | 2 | hSpCas9 | negative selection | 2289138 | 144517755 | 144517778 | 8 | - | 24336569 | HL60 | viability | GGCTGCGGGACGTGCGGGAGCGG | RECQL4 | ENSG00000160957 | -0.594425923655007 | [766] | [1074] | -5 | hSpCas9 | negative selection | 2289139 | 144517760 | 144517783 | 8 | - | 24336569 | HL60 | viability | GGAGCGGCTGCGGGACGTGCGGG | RECQL4 | ENSG00000160957 | -0.9239228236424164 | [545] | [608] | -7 | hSpCas9 | negative selection | 2289140 | 144517769 | 144517792 | 8 | - | 24336569 | HL60 | viability | GCGCGCCATGGAGCGGCTGCGGG | RECQL4 | ENSG00000160957 | -0.16031952134013594 | [281] | [533] | -1 | hSpCas9 | negative selection | 2289141 | 144517620 | 144517643 | 8 | - | 24336569 | KBM7 | viability | TTTACAGGACGACGTGGAGGCGG | RECQL4 | ENSG00000160957 | -0.48751794191902653 | [585] | [1139] | -4 | hSpCas9 | negative selection | 2356309 | 144517626 | 144517649 | 8 | - | 24336569 | KBM7 | viability | GTTCCCTTTACAGGACGACGTGG | RECQL4 | ENSG00000160957 | -0.5865024629499428 | [304] | [553] | -5 | hSpCas9 | negative selection | 2356310 | 144517687 | 144517710 | 8 | + | 24336569 | KBM7 | viability | TGGGCAGCCCGCACCTGGCTCGG | RECQL4 | ENSG00000160957 | -0.39770328990931303 | [397] | [823] | -3 | hSpCas9 | negative selection | 2356311 | 144517716 | 144517739 | 8 | - | 24336569 | KBM7 | viability | GCGCGTTCCGACGGCAGCGCGGG | RECQL4 | ENSG00000160957 | -1.0612734158133548 | [709] | [927] | -6 | hSpCas9 | negative selection | 2356312 | 144517725 | 144517748 | 8 | - | 24336569 | KBM7 | viability | CGTGGGAGCGCGCGTTCCGACGG | RECQL4 | ENSG00000160957 | -0.07513357399450671 | [274] | [711] | 0 | hSpCas9 | negative selection | 2356313 | 144517742 | 144517765 | 8 | - | 24336569 | KBM7 | viability | GCGGGAGCGGCTGCAGGCGTGGG | RECQL4 | ENSG00000160957 | -1.4249777676117497 | [759] | [771] | -7 | hSpCas9 | negative selection | 2356314 | 144517748 | 144517771 | 8 | - | 24336569 | KBM7 | viability | GGACGTGCGGGAGCGGCTGCAGG | RECQL4 | ENSG00000160957 | -0.8227023262766753 | [807] | [1245] | -6 | hSpCas9 | negative selection | 2356315 | 144517755 | 144517778 | 8 | - | 24336569 | KBM7 | viability | GGCTGCGGGACGTGCGGGAGCGG | RECQL4 | ENSG00000160957 | 0.19994161716826425 | [518] | [1625] | 1 | hSpCas9 | negative selection | 2356316 | 144517760 | 144517783 | 8 | - | 24336569 | KBM7 | viability | GGAGCGGCTGCGGGACGTGCGGG | RECQL4 | ENSG00000160957 | -1.741798307568202 | [476] | [388] | -8 | hSpCas9 | negative selection | 2356317 | 144517769 | 144517792 | 8 | - | 24336569 | KBM7 | viability | GCGCGCCATGGAGCGGCTGCGGG | RECQL4 | ENSG00000160957 | 0.49523097331457877 | [237] | [914] | 4 | hSpCas9 | negative selection | 2356318 | 144517800 | 144517823 | 8 | - | 25494202 | A375 | resistance to PLX-4720 (puromycin) | ACGATCGCAAGCGCGGAGGCCGG | RECQL4 | ENSG00000160957 | 0.5865374748065965 | [86,224] | [28,75] | 2 | dCas9-VP64 | positive selection | 2444754 | 144517823 | 144517846 | 8 | - | 25494202 | A375 | resistance to PLX-4720 (puromycin) | CGGCTGCGCGGGAGATTCGCTGG | RECQL4 | ENSG00000160957 | 5.176087694795539 | [64,63] | [959,44] | 9 | dCas9-VP64 | positive selection | 2444755 | 144517800 | 144517823 | 8 | - | 25494202 | A375 | resistance to PLX-4720 (zeocin) | ACGATCGCAAGCGCGGAGGCCGG | RECQL4 | ENSG00000160957 | -0.3945952060694746 | [169,55] | [36,19] | -4 | dCas9-VP64 | positive selection | 2540009 | 144517823 | 144517846 | 8 | - | 25494202 | A375 | resistance to PLX-4720 (zeocin) | CGGCTGCGCGGGAGATTCGCTGG | RECQL4 | ENSG00000160957 | -0.5045633184234422 | [33,106] | [8,21] | -5 | dCas9-VP64 | positive selection | 2540010 | 144517725 | 144517748 | 8 | - | 27383988 | 293T | resistance to West Nile virus (flavivirus) | CGTGGGAGCGCGCGTTCCGACGG | RECQL4 | ENSG00000160957 | 0.5568864933047428 | [103,103] | [0,0] | 3 | hSpCas9 | positive selection | 3389429 | 144517075 | 144517098 | 8 | + | 27383988 | 293T | resistance to West Nile virus (flavivirus) | TTGAGCCGCTGCCCGTAGTCCGG | RECQL4 | ENSG00000160957 | 0.07741712143090065 | [144,144] | [0,0] | 0 | hSpCas9 | positive selection | 3389430 | 144517595 | 144517618 | 8 | + | 27383988 | 293T | resistance to West Nile virus (flavivirus) | CGCTCACCGCGGGTCTCCTCCGG | RECQL4 | ENSG00000160957 | 2.2129320920873816 | [32,32] | [0,0] | 7 | hSpCas9 | positive selection | 3389431 | 144517120 | 144517143 | 8 | - | 26780180 | A375 | viability | AAGAGTCCACAGTCTACGCCAGG | RECQL4 | ENSG00000160957 | 1.65554493558246 | [] | [] | 8 | hSpCas9 | negative selection | 3988242 | 144517623 | 144517646 | 8 | - | 26780180 | A375 | viability | CCCTTTACAGGACGACGTGGAGG | RECQL4 | ENSG00000160957 | 1.73944638277058 | [] | [] | 9 | hSpCas9 | negative selection | 3988243 | 144517595 | 144517618 | 8 | + | 26780180 | A375 | viability | CGCTCACCGCGGGTCTCCTCCGG | RECQL4 | ENSG00000160957 | 0.620580553658477 | [] | [] | 2 | hSpCas9 | negative selection | 3988244 | 144517725 | 144517748 | 8 | - | 26780180 | A375 | viability | CGTGGGAGCGCGCGTTCCGACGG | RECQL4 | ENSG00000160957 | 1.57912482594592 | [] | [] | 8 | hSpCas9 | negative selection | 3988245 | 144517807 | 144517830 | 8 | - | 26780180 | A375 | viability | TCGCTGGACGATCGCAAGCGCGG | RECQL4 | ENSG00000160957 | 0.743914430846183 | [] | [] | 2 | hSpCas9 | negative selection | 3988246 | 144517075 | 144517098 | 8 | + | 26780180 | A375 | viability | TTGAGCCGCTGCCCGTAGTCCGG | RECQL4 | ENSG00000160957 | 1.29282602851327 | [] | [] | 7 | hSpCas9 | negative selection | 3988247 | 144517120 | 144517143 | 8 | - | 26780180 | HT29 | viability (GeCKOv2 library) | AAGAGTCCACAGTCTACGCCAGG | RECQL4 | ENSG00000160957 | 2.12330536065236 | [] | [] | 9 | hSpCas9 | negative selection | 4096208 | 144517623 | 144517646 | 8 | - | 26780180 | HT29 | viability (GeCKOv2 library) | CCCTTTACAGGACGACGTGGAGG | RECQL4 | ENSG00000160957 | 1.74277523159003 | [] | [] | 8 | hSpCas9 | negative selection | 4096209 | 144517595 | 144517618 | 8 | + | 26780180 | HT29 | viability (GeCKOv2 library) | CGCTCACCGCGGGTCTCCTCCGG | RECQL4 | ENSG00000160957 | 1.08389919565402 | [] | [] | 5 | hSpCas9 | negative selection | 4096210 | 144517725 | 144517748 | 8 | - | 26780180 | HT29 | viability (GeCKOv2 library) | CGTGGGAGCGCGCGTTCCGACGG | RECQL4 | ENSG00000160957 | 1.8494399432908 | [] | [] | 8 | hSpCas9 | negative selection | 4096211 | 144517807 | 144517830 | 8 | - | 26780180 | HT29 | viability (GeCKOv2 library) | TCGCTGGACGATCGCAAGCGCGG | RECQL4 | ENSG00000160957 | 0.505112192689629 | [] | [] | 1 | hSpCas9 | negative selection | 4096212 | 144517075 | 144517098 | 8 | + | 26780180 | HT29 | viability (GeCKOv2 library) | TTGAGCCGCTGCCCGTAGTCCGG | RECQL4 | ENSG00000160957 | 2.20462626643423 | [] | [] | 9 | hSpCas9 | negative selection | 4096213 | 144517807 | 144517830 | 8 | - | 26780180 | A375 | resistance to vemurafenib (GeCKOv2 lentiGuide) | TCGCTGGACGATCGCAAGCGCGG | RECQL4 | ENSG00000160957 | 0.08349705710903088 | [1] | [1,0] | 1 | hSpCas9 | positive selection | 4294401 | 144517623 | 144517646 | 8 | - | 26780180 | A375 | resistance to vemurafenib (GeCKOv2 lentiGuide) | CCCTTTACAGGACGACGTGGAGG | RECQL4 | ENSG00000160957 | -0.4235609963592992 | [2] | [1,0] | -7 | hSpCas9 | positive selection | 4294402 | 144517120 | 144517143 | 8 | - | 26780180 | A375 | resistance to vemurafenib (GeCKOv2 lentiGuide) | AAGAGTCCACAGTCTACGCCAGG | RECQL4 | ENSG00000160957 | 0.17046659012350907 | [2] | [2,2] | 3 | hSpCas9 | positive selection | 4294403 | 144517725 | 144517748 | 8 | - | 26780180 | A375 | resistance to vemurafenib (GeCKOv2 lentiGuide) | CGTGGGAGCGCGCGTTCCGACGG | RECQL4 | ENSG00000160957 | -0.5094170167739814 | [2] | [2,0] | -8 | hSpCas9 | positive selection | 4358657 | 144517075 | 144517098 | 8 | + | 26780180 | A375 | resistance to vemurafenib (GeCKOv2 lentiGuide) | TTGAGCCGCTGCCCGTAGTCCGG | RECQL4 | ENSG00000160957 | -0.624489528846651 | [2] | [1,0] | -8 | hSpCas9 | positive selection | 4358658 | 144517595 | 144517618 | 8 | + | 26780180 | A375 | resistance to vemurafenib (GeCKOv2 lentiGuide) | CGCTCACCGCGGGTCTCCTCCGG | RECQL4 | ENSG00000160957 | -0.5975214512852501 | [1] | [0,0] | -8 | hSpCas9 | positive selection | 4358659 | 144517557 | 144517580 | 8 | - | 27661255 | K562 | viability | GGGGCGAGAAGACACCGGGTCGG | RECQL4 | ENSG00000160957 | -1.3755489971036328 | [776,897] | [254,258] | -9 | dCas9-KRAB | negative selection | 5506822 | 144517601 | 144517624 | 8 | - | 27661255 | K562 | viability | GCGGCGCCGGAGGAGACCCGCGG | RECQL4 | ENSG00000160957 | 0.07489097318112448 | [410,477] | [440,314] | 2 | dCas9-KRAB | negative selection | 5506823 | 144517760 | 144517783 | 8 | - | 27661255 | K562 | viability | GGAGCGGCTGCGGGACGTGCGGG | RECQL4 | ENSG00000160957 | 0.35900757571755026 | [497,608] | [591,541] | 9 | dCas9-KRAB | negative selection | 5506824 | 144517807 | 144517830 | 8 | - | 27260156 | BXPC3 | viability | TCGCTGGACGATCGCAAGCGCGG | RECQL4 | ENSG00000160957 | 0.4195550799583936 | [87] | [131,119,118,118] | 8 | hSpCas9 | negative selection | 5566861 | 144517623 | 144517646 | 8 | - | 27260156 | BXPC3 | viability | CCCTTTACAGGACGACGTGGAGG | RECQL4 | ENSG00000160957 | -0.16787299071179718 | [255] | [161,216,270,321] | -4 | hSpCas9 | negative selection | 5566862 | 144517120 | 144517143 | 8 | - | 27260156 | BXPC3 | viability | AAGAGTCCACAGTCTACGCCAGG | RECQL4 | ENSG00000160957 | 0.3969062467766324 | [417] | [554,529,592,631] | 8 | hSpCas9 | negative selection | 5566863 | 144517725 | 144517748 | 8 | - | 27260156 | BXPC3 | viability | CGTGGGAGCGCGCGTTCCGACGG | RECQL4 | ENSG00000160957 | -0.4589844602756339 | [425] | [297,365,320,306] | -7 | hSpCas9 | negative selection | 5631117 | 144517075 | 144517098 | 8 | + | 27260156 | BXPC3 | viability | TTGAGCCGCTGCCCGTAGTCCGG | RECQL4 | ENSG00000160957 | 0.44371581075375555 | [335] | [358,371,612,600] | 8 | hSpCas9 | negative selection | 5631118 | 144517595 | 144517618 | 8 | + | 27260156 | BXPC3 | viability | CGCTCACCGCGGGTCTCCTCCGG | RECQL4 | ENSG00000160957 | 0.8622848434208326 | [102] | [156,91,349,195] | 9 | hSpCas9 | negative selection | 5631119 | 144517807 | 144517830 | 8 | - | 27260156 | A673 | viability | TCGCTGGACGATCGCAAGCGCGG | RECQL4 | ENSG00000160957 | 0.14083416007119443 | [87] | [109,113,109,131] | 3 | hSpCas9 | negative selection | 5688112 | 144517623 | 144517646 | 8 | - | 27260156 | A673 | viability | CCCTTTACAGGACGACGTGGAGG | RECQL4 | ENSG00000160957 | -0.24362560095833208 | [255] | [231,266,296,236] | -5 | hSpCas9 | negative selection | 5688113 | 144517120 | 144517143 | 8 | - | 27260156 | A673 | viability | AAGAGTCCACAGTCTACGCCAGG | RECQL4 | ENSG00000160957 | 0.4012240729908684 | [417] | [682,683,667,613] | 8 | hSpCas9 | negative selection | 5688114 | 144517725 | 144517748 | 8 | - | 27260156 | A673 | viability | CGTGGGAGCGCGCGTTCCGACGG | RECQL4 | ENSG00000160957 | -0.42753291026558105 | [425] | [400,382,446,285] | -8 | hSpCas9 | negative selection | 5752368 | 144517075 | 144517098 | 8 | + | 27260156 | A673 | viability | TTGAGCCGCTGCCCGTAGTCCGG | RECQL4 | ENSG00000160957 | 0.22416265794853346 | [335] | [582,394,481,436] | 5 | hSpCas9 | negative selection | 5752369 | 144517595 | 144517618 | 8 | + | 27260156 | A673 | viability | CGCTCACCGCGGGTCTCCTCCGG | RECQL4 | ENSG00000160957 | 0.27351435145215786 | [102] | [177,191,116,110] | 6 | hSpCas9 | negative selection | 5752370 | 144517807 | 144517830 | 8 | - | 27260156 | A375 | viability | TCGCTGGACGATCGCAAGCGCGG | RECQL4 | ENSG00000160957 | -0.00517560745078427 | [87] | [72,189,62,95] | 0 | hSpCas9 | negative selection | 5809363 | 144517623 | 144517646 | 8 | - | 27260156 | A375 | viability | CCCTTTACAGGACGACGTGGAGG | RECQL4 | ENSG00000160957 | -1.08380056561768 | [255] | [208,67,153,124] | -8 | hSpCas9 | negative selection | 5809364 | 144517120 | 144517143 | 8 | - | 27260156 | A375 | viability | AAGAGTCCACAGTCTACGCCAGG | RECQL4 | ENSG00000160957 | 0.7234441750835764 | [417] | [753,774,792,884] | 9 | hSpCas9 | negative selection | 5809365 | 144517725 | 144517748 | 8 | - | 27260156 | A375 | viability | CGTGGGAGCGCGCGTTCCGACGG | RECQL4 | ENSG00000160957 | -1.2409536141666606 | [425] | [160,164,255,247] | -8 | hSpCas9 | negative selection | 5873619 | 144517075 | 144517098 | 8 | + | 27260156 | A375 | viability | TTGAGCCGCTGCCCGTAGTCCGG | RECQL4 | ENSG00000160957 | -0.08988271193124614 | [335] | [251,495,397,346] | -1 | hSpCas9 | negative selection | 5873620 | 144517595 | 144517618 | 8 | + | 27260156 | A375 | viability | CGCTCACCGCGGGTCTCCTCCGG | RECQL4 | ENSG00000160957 | -1.4411097326518427 | [102] | [70,77,16,18] | -9 | hSpCas9 | negative selection | 5873621 | 144517807 | 144517830 | 8 | - | 27260156 | COLO741 | viability | TCGCTGGACGATCGCAAGCGCGG | RECQL4 | ENSG00000160957 | 0.38202143542389333 | [87] | [155,150,133] | 7 | hSpCas9 | negative selection | 5930614 | 144517623 | 144517646 | 8 | - | 27260156 | COLO741 | viability | CCCTTTACAGGACGACGTGGAGG | RECQL4 | ENSG00000160957 | -0.10510950230363769 | [255] | [323,308,281] | -2 | hSpCas9 | negative selection | 5930615 | 144517120 | 144517143 | 8 | - | 27260156 | COLO741 | viability | AAGAGTCCACAGTCTACGCCAGG | RECQL4 | ENSG00000160957 | 0.4169769766383342 | [417] | [892,692,576] | 8 | hSpCas9 | negative selection | 5930616 | 144517725 | 144517748 | 8 | - | 27260156 | COLO741 | viability | CGTGGGAGCGCGCGTTCCGACGG | RECQL4 | ENSG00000160957 | -0.5933921694575452 | [425] | [396,403,288] | -8 | hSpCas9 | negative selection | 5994870 | 144517075 | 144517098 | 8 | + | 27260156 | COLO741 | viability | TTGAGCCGCTGCCCGTAGTCCGG | RECQL4 | ENSG00000160957 | 0.03343013177393417 | [335] | [581,419,334] | 0 | hSpCas9 | negative selection | 5994871 | 144517595 | 144517618 | 8 | + | 27260156 | COLO741 | viability | CGCTCACCGCGGGTCTCCTCCGG | RECQL4 | ENSG00000160957 | 0.18800645894080414 | [102] | [197,71,180] | 4 | hSpCas9 | negative selection | 5994872 | 144517807 | 144517830 | 8 | - | 27260156 | CAL120 | viability | TCGCTGGACGATCGCAAGCGCGG | RECQL4 | ENSG00000160957 | -0.18937071871386113 | [87] | [50,117,111] | -3 | hSpCas9 | negative selection | 6051865 | 144517623 | 144517646 | 8 | - | 27260156 | CAL120 | viability | CCCTTTACAGGACGACGTGGAGG | RECQL4 | ENSG00000160957 | -0.21489100076170276 | [255] | [196,414,200] | -3 | hSpCas9 | negative selection | 6051866 | 144517120 | 144517143 | 8 | - | 27260156 | CAL120 | viability | AAGAGTCCACAGTCTACGCCAGG | RECQL4 | ENSG00000160957 | 0.13084743666566553 | [417] | [886,347,521] | 2 | hSpCas9 | negative selection | 6051867 | 144517725 | 144517748 | 8 | - | 27260156 | CAL120 | viability | CGTGGGAGCGCGCGTTCCGACGG | RECQL4 | ENSG00000160957 | -0.6281564620189841 | [425] | [370,317,343] | -7 | hSpCas9 | negative selection | 6116121 | 144517075 | 144517098 | 8 | + | 27260156 | CAL120 | viability | TTGAGCCGCTGCCCGTAGTCCGG | RECQL4 | ENSG00000160957 | 0.2815750080277314 | [335] | [431,460,617] | 4 | hSpCas9 | negative selection | 6116122 | 144517595 | 144517618 | 8 | + | 27260156 | CAL120 | viability | CGCTCACCGCGGGTCTCCTCCGG | RECQL4 | ENSG00000160957 | -0.7222858964048053 | [102] | [36,116,72] | -7 | hSpCas9 | negative selection | 6116123 | 144517807 | 144517830 | 8 | - | 27260156 | CADOES1 | viability | TCGCTGGACGATCGCAAGCGCGG | RECQL4 | ENSG00000160957 | 0.041060808641874225 | [87] | [134,64,94,39] | 0 | hSpCas9 | negative selection | 6173116 | 144517623 | 144517646 | 8 | - | 27260156 | CADOES1 | viability | CCCTTTACAGGACGACGTGGAGG | RECQL4 | ENSG00000160957 | -0.6085070147663224 | [255] | [137,131,188,165] | -8 | hSpCas9 | negative selection | 6173117 | 144517120 | 144517143 | 8 | - | 27260156 | CADOES1 | viability | AAGAGTCCACAGTCTACGCCAGG | RECQL4 | ENSG00000160957 | 0.2982512377827537 | [417] | [556,446,427,479] | 5 | hSpCas9 | negative selection | 6173118 | 144517725 | 144517748 | 8 | - | 27260156 | CADOES1 | viability | CGTGGGAGCGCGCGTTCCGACGG | RECQL4 | ENSG00000160957 | -1.0424729680242422 | [425] | [226,139,189,212] | -9 | hSpCas9 | negative selection | 6237372 | 144517075 | 144517098 | 8 | + | 27260156 | CADOES1 | viability | TTGAGCCGCTGCCCGTAGTCCGG | RECQL4 | ENSG00000160957 | 0.2947615018836731 | [335] | [524,438,316,246] | 5 | hSpCas9 | negative selection | 6237373 | 144517595 | 144517618 | 8 | + | 27260156 | CADOES1 | viability | CGCTCACCGCGGGTCTCCTCCGG | RECQL4 | ENSG00000160957 | -0.38844629076124315 | [102] | [37,81,69,103] | -6 | hSpCas9 | negative selection | 6237374 | 144517807 | 144517830 | 8 | - | 27260156 | EWS502 | viability | TCGCTGGACGATCGCAAGCGCGG | RECQL4 | ENSG00000160957 | 0.03745427815371061 | [87] | [86,120,62,111] | 0 | hSpCas9 | negative selection | 6294367 | 144517623 | 144517646 | 8 | - | 27260156 | EWS502 | viability | CCCTTTACAGGACGACGTGGAGG | RECQL4 | ENSG00000160957 | -0.5922064285394918 | [255] | [134,184,121,288] | -7 | hSpCas9 | negative selection | 6294368 | 144517120 | 144517143 | 8 | - | 27260156 | EWS502 | viability | AAGAGTCCACAGTCTACGCCAGG | RECQL4 | ENSG00000160957 | 0.4010077702913475 | [417] | [548,534,686,571] | 7 | hSpCas9 | negative selection | 6294369 | 144517725 | 144517748 | 8 | - | 27260156 | EWS502 | viability | CGTGGGAGCGCGCGTTCCGACGG | RECQL4 | ENSG00000160957 | -0.37276279630404774 | [425] | [315,399,507,158] | -6 | hSpCas9 | negative selection | 6358623 | 144517075 | 144517098 | 8 | + | 27260156 | EWS502 | viability | TTGAGCCGCTGCCCGTAGTCCGG | RECQL4 | ENSG00000160957 | 0.7199133562498661 | [335] | [348,756,631,629] | 9 | hSpCas9 | negative selection | 6358624 | 144517595 | 144517618 | 8 | + | 27260156 | EWS502 | viability | CGCTCACCGCGGGTCTCCTCCGG | RECQL4 | ENSG00000160957 | -0.16324741014117983 | [102] | [73,99,110,107] | -3 | hSpCas9 | negative selection | 6358625 | 144517807 | 144517830 | 8 | - | 27260156 | EW8 | viability | TCGCTGGACGATCGCAAGCGCGG | RECQL4 | ENSG00000160957 | -0.22007096698979245 | [87] | [69,27,105,33] | -4 | hSpCas9 | negative selection | 6415618 | 144517623 | 144517646 | 8 | - | 27260156 | EW8 | viability | CCCTTTACAGGACGACGTGGAGG | RECQL4 | ENSG00000160957 | -0.601496169738546 | [255] | [220,113,117,105] | -8 | hSpCas9 | negative selection | 6415619 | 144517120 | 144517143 | 8 | - | 27260156 | EW8 | viability | AAGAGTCCACAGTCTACGCCAGG | RECQL4 | ENSG00000160957 | 0.5845274990133942 | [417] | [506,467,453,609] | 8 | hSpCas9 | negative selection | 6415620 | 144517725 | 144517748 | 8 | - | 27260156 | EW8 | viability | CGTGGGAGCGCGCGTTCCGACGG | RECQL4 | ENSG00000160957 | -0.6894920315595201 | [425] | [255,182,202,219] | -8 | hSpCas9 | negative selection | 6479874 | 144517075 | 144517098 | 8 | + | 27260156 | EW8 | viability | TTGAGCCGCTGCCCGTAGTCCGG | RECQL4 | ENSG00000160957 | 0.16899031733280812 | [335] | [268,285,337,320] | 3 | hSpCas9 | negative selection | 6479875 | 144517595 | 144517618 | 8 | + | 27260156 | EW8 | viability | CGCTCACCGCGGGTCTCCTCCGG | RECQL4 | ENSG00000160957 | 0.14117320862656957 | [102] | [85,99,63,121] | 2 | hSpCas9 | negative selection | 6479876 | 144517807 | 144517830 | 8 | - | 27260156 | CORL105 | viability | TCGCTGGACGATCGCAAGCGCGG | RECQL4 | ENSG00000160957 | -0.036135491293096234 | [87] | [60,129,94,112] | 0 | hSpCas9 | negative selection | 6536869 | 144517623 | 144517646 | 8 | - | 27260156 | CORL105 | viability | CCCTTTACAGGACGACGTGGAGG | RECQL4 | ENSG00000160957 | -1.0769806126288461 | [255] | [142,132,120,167] | -9 | hSpCas9 | negative selection | 6536870 | 144517120 | 144517143 | 8 | - | 27260156 | CORL105 | viability | AAGAGTCCACAGTCTACGCCAGG | RECQL4 | ENSG00000160957 | 0.124592550461741 | [417] | [702,591,424,401] | 2 | hSpCas9 | negative selection | 6536871 | 144517725 | 144517748 | 8 | - | 27260156 | CORL105 | viability | CGTGGGAGCGCGCGTTCCGACGG | RECQL4 | ENSG00000160957 | -0.6181479482794008 | [425] | [341,283,475,222] | -8 | hSpCas9 | negative selection | 6601125 | 144517075 | 144517098 | 8 | + | 27260156 | CORL105 | viability | TTGAGCCGCTGCCCGTAGTCCGG | RECQL4 | ENSG00000160957 | 0.03646965209116809 | [335] | [468,293,504,365] | 0 | hSpCas9 | negative selection | 6601126 | 144517595 | 144517618 | 8 | + | 27260156 | CORL105 | viability | CGCTCACCGCGGGTCTCCTCCGG | RECQL4 | ENSG00000160957 | -0.5834649899374171 | [102] | [83,79,92,66] | -8 | hSpCas9 | negative selection | 6601127 | 144517807 | 144517830 | 8 | - | 27260156 | HS294T | viability | TCGCTGGACGATCGCAAGCGCGG | RECQL4 | ENSG00000160957 | -0.5255932863964623 | [87] | [10,35,20,27] | -6 | hSpCas9 | negative selection | 6658120 | 144517623 | 144517646 | 8 | - | 27260156 | HS294T | viability | CCCTTTACAGGACGACGTGGAGG | RECQL4 | ENSG00000160957 | -0.9549588491248514 | [255] | [48,48,51,54] | -8 | hSpCas9 | negative selection | 6658121 | 144517120 | 144517143 | 8 | - | 27260156 | HS294T | viability | AAGAGTCCACAGTCTACGCCAGG | RECQL4 | ENSG00000160957 | 0.5801868985512629 | [417] | [223,274,261,197] | 7 | hSpCas9 | negative selection | 6658122 | 144517725 | 144517748 | 8 | - | 27260156 | HS294T | viability | CGTGGGAGCGCGCGTTCCGACGG | RECQL4 | ENSG00000160957 | -0.8643608768443312 | [425] | [50,134,76,102] | -8 | hSpCas9 | negative selection | 6722376 | 144517075 | 144517098 | 8 | + | 27260156 | HS294T | viability | TTGAGCCGCTGCCCGTAGTCCGG | RECQL4 | ENSG00000160957 | 0.7105206491749501 | [335] | [263,145,183,260] | 8 | hSpCas9 | negative selection | 6722377 | 144517595 | 144517618 | 8 | + | 27260156 | HS294T | viability | CGCTCACCGCGGGTCTCCTCCGG | RECQL4 | ENSG00000160957 | -0.2209343766288394 | [102] | [14,16,32,81] | -3 | hSpCas9 | negative selection | 6722378 | 144517807 | 144517830 | 8 | - | 27260156 | HCC44 | viability | TCGCTGGACGATCGCAAGCGCGG | RECQL4 | ENSG00000160957 | -0.6013421891478252 | [87] | [35,72,72,76] | -7 | hSpCas9 | negative selection | 6779371 | 144517623 | 144517646 | 8 | - | 27260156 | HCC44 | viability | CCCTTTACAGGACGACGTGGAGG | RECQL4 | ENSG00000160957 | -0.6149054771102945 | [255] | [155,145,287,184] | -7 | hSpCas9 | negative selection | 6779372 | 144517120 | 144517143 | 8 | - | 27260156 | HCC44 | viability | AAGAGTCCACAGTCTACGCCAGG | RECQL4 | ENSG00000160957 | 0.6910112055078224 | [417] | [731,604,899,849] | 9 | hSpCas9 | negative selection | 6779373 | 144517725 | 144517748 | 8 | - | 27260156 | HCC44 | viability | CGTGGGAGCGCGCGTTCCGACGG | RECQL4 | ENSG00000160957 | -0.7262352104323462 | [425] | [370,159,435,247] | -8 | hSpCas9 | negative selection | 6843627 | 144517075 | 144517098 | 8 | + | 27260156 | HCC44 | viability | TTGAGCCGCTGCCCGTAGTCCGG | RECQL4 | ENSG00000160957 | 0.2709140388743762 | [335] | [327,449,470,568] | 4 | hSpCas9 | negative selection | 6843628 | 144517595 | 144517618 | 8 | + | 27260156 | HCC44 | viability | CGCTCACCGCGGGTCTCCTCCGG | RECQL4 | ENSG00000160957 | -0.4415226292154082 | [102] | [56,66,60,150] | -6 | hSpCas9 | negative selection | 6843629 | 144517807 | 144517830 | 8 | - | 27260156 | G402 | viability | TCGCTGGACGATCGCAAGCGCGG | RECQL4 | ENSG00000160957 | 0.12521445328323066 | [87] | [139,106,154,70] | 1 | hSpCas9 | negative selection | 6900622 | 144517623 | 144517646 | 8 | - | 27260156 | G402 | viability | CCCTTTACAGGACGACGTGGAGG | RECQL4 | ENSG00000160957 | -0.4727620866091734 | [255] | [193,258,261,183] | -5 | hSpCas9 | negative selection | 6900623 | 144517120 | 144517143 | 8 | - | 27260156 | G402 | viability | AAGAGTCCACAGTCTACGCCAGG | RECQL4 | ENSG00000160957 | 0.626566696811454 | [417] | [908,903,653,707] | 7 | hSpCas9 | negative selection | 6900624 | 144517725 | 144517748 | 8 | - | 27260156 | G402 | viability | CGTGGGAGCGCGCGTTCCGACGG | RECQL4 | ENSG00000160957 | -0.8768705639093304 | [425] | [200,239,248,419] | -8 | hSpCas9 | negative selection | 6964878 | 144517075 | 144517098 | 8 | + | 27260156 | G402 | viability | TTGAGCCGCTGCCCGTAGTCCGG | RECQL4 | ENSG00000160957 | 0.280589873043891 | [335] | [709,413,566,332] | 3 | hSpCas9 | negative selection | 6964879 | 144517595 | 144517618 | 8 | + | 27260156 | G402 | viability | CGCTCACCGCGGGTCTCCTCCGG | RECQL4 | ENSG00000160957 | -1.4649488470554308 | [102] | [56,84,21,22] | -9 | hSpCas9 | negative selection | 6964880 | 144517807 | 144517830 | 8 | - | 27260156 | L33 | viability | TCGCTGGACGATCGCAAGCGCGG | RECQL4 | ENSG00000160957 | 0.13497506294035722 | [87] | [97,54,61,55] | 3 | hSpCas9 | negative selection | 7021873 | 144517623 | 144517646 | 8 | - | 27260156 | L33 | viability | CCCTTTACAGGACGACGTGGAGG | RECQL4 | ENSG00000160957 | -0.3076633892452948 | [255] | [147,100,140,209] | -6 | hSpCas9 | negative selection | 7021874 | 144517120 | 144517143 | 8 | - | 27260156 | L33 | viability | AAGAGTCCACAGTCTACGCCAGG | RECQL4 | ENSG00000160957 | 0.2883491633343276 | [417] | [571,157,370,492] | 6 | hSpCas9 | negative selection | 7021875 | 144517725 | 144517748 | 8 | - | 27260156 | L33 | viability | CGTGGGAGCGCGCGTTCCGACGG | RECQL4 | ENSG00000160957 | -0.588189424747104 | [425] | [221,141,209,232] | -8 | hSpCas9 | negative selection | 7086129 | 144517075 | 144517098 | 8 | + | 27260156 | L33 | viability | TTGAGCCGCTGCCCGTAGTCCGG | RECQL4 | ENSG00000160957 | 0.5936972476532776 | [335] | [513,201,368,434] | 9 | hSpCas9 | negative selection | 7086130 | 144517595 | 144517618 | 8 | + | 27260156 | L33 | viability | CGCTCACCGCGGGTCTCCTCCGG | RECQL4 | ENSG00000160957 | -0.1952654325546459 | [102] | [93,42,53,74] | -4 | hSpCas9 | negative selection | 7086131 | 144517807 | 144517830 | 8 | - | 27260156 | K562 | viability | TCGCTGGACGATCGCAAGCGCGG | RECQL4 | ENSG00000160957 | -0.08662416189738709 | [87] | [72,196,19,16] | -1 | hSpCas9 | negative selection | 7143124 | 144517623 | 144517646 | 8 | - | 27260156 | K562 | viability | CCCTTTACAGGACGACGTGGAGG | RECQL4 | ENSG00000160957 | -0.29655534552721463 | [255] | [96,296,226,123] | -4 | hSpCas9 | negative selection | 7143125 | 144517120 | 144517143 | 8 | - | 27260156 | K562 | viability | AAGAGTCCACAGTCTACGCCAGG | RECQL4 | ENSG00000160957 | 0.06332367579225982 | [417] | [391,301,202,619] | 0 | hSpCas9 | negative selection | 7143126 | 144517725 | 144517748 | 8 | - | 27260156 | K562 | viability | CGTGGGAGCGCGCGTTCCGACGG | RECQL4 | ENSG00000160957 | -0.26304859588801865 | [425] | [386,287,449,156] | -3 | hSpCas9 | negative selection | 7207380 | 144517075 | 144517098 | 8 | + | 27260156 | K562 | viability | TTGAGCCGCTGCCCGTAGTCCGG | RECQL4 | ENSG00000160957 | 0.7074418963016851 | [335] | [283,502,648,492] | 8 | hSpCas9 | negative selection | 7207381 | 144517595 | 144517618 | 8 | + | 27260156 | K562 | viability | CGCTCACCGCGGGTCTCCTCCGG | RECQL4 | ENSG00000160957 | -0.2835469636560499 | [102] | [43,44,56,141] | -4 | hSpCas9 | negative selection | 7207382 | 144517807 | 144517830 | 8 | - | 27260156 | HT29 | viability | TCGCTGGACGATCGCAAGCGCGG | RECQL4 | ENSG00000160957 | 0.0025003134341852196 | [87] | [161,140,51,82] | 0 | hSpCas9 | negative selection | 7264375 | 144517623 | 144517646 | 8 | - | 27260156 | HT29 | viability | CCCTTTACAGGACGACGTGGAGG | RECQL4 | ENSG00000160957 | -0.9186977253062364 | [255] | [204,250,84,130] | -8 | hSpCas9 | negative selection | 7264376 | 144517120 | 144517143 | 8 | - | 27260156 | HT29 | viability | AAGAGTCCACAGTCTACGCCAGG | RECQL4 | ENSG00000160957 | -0.048830317250469074 | [417] | [455,563,544,409] | -1 | hSpCas9 | negative selection | 7264377 | 144517725 | 144517748 | 8 | - | 27260156 | HT29 | viability | CGTGGGAGCGCGCGTTCCGACGG | RECQL4 | ENSG00000160957 | -0.859919448043488 | [425] | [271,353,222,293] | -8 | hSpCas9 | negative selection | 7328631 | 144517075 | 144517098 | 8 | + | 27260156 | HT29 | viability | TTGAGCCGCTGCCCGTAGTCCGG | RECQL4 | ENSG00000160957 | -0.10237878899478575 | [335] | [384,411,477,261] | -2 | hSpCas9 | negative selection | 7328632 | 144517595 | 144517618 | 8 | + | 27260156 | HT29 | viability | CGCTCACCGCGGGTCTCCTCCGG | RECQL4 | ENSG00000160957 | -0.8775367505814136 | [102] | [102,46,90,35] | -8 | hSpCas9 | negative selection | 7328633 | 144517807 | 144517830 | 8 | - | 27260156 | MHHES1 | viability | TCGCTGGACGATCGCAAGCGCGG | RECQL4 | ENSG00000160957 | 0.5702158415025298 | [87] | [136,144,266,56] | 8 | hSpCas9 | negative selection | 7385626 | 144517623 | 144517646 | 8 | - | 27260156 | MHHES1 | viability | CCCTTTACAGGACGACGTGGAGG | RECQL4 | ENSG00000160957 | -0.2726732696294506 | [255] | [302,181,125,319] | -5 | hSpCas9 | negative selection | 7385627 | 144517120 | 144517143 | 8 | - | 27260156 | MHHES1 | viability | AAGAGTCCACAGTCTACGCCAGG | RECQL4 | ENSG00000160957 | 0.33005148494825576 | [417] | [701,699,623,397] | 6 | hSpCas9 | negative selection | 7385628 | 144517725 | 144517748 | 8 | - | 27260156 | MHHES1 | viability | CGTGGGAGCGCGCGTTCCGACGG | RECQL4 | ENSG00000160957 | -0.6959512644782982 | [425] | [278,353,270,280] | -8 | hSpCas9 | negative selection | 7449882 | 144517075 | 144517098 | 8 | + | 27260156 | MHHES1 | viability | TTGAGCCGCTGCCCGTAGTCCGG | RECQL4 | ENSG00000160957 | -0.1155897031635949 | [335] | [519,378,236,289] | -2 | hSpCas9 | negative selection | 7449883 | 144517595 | 144517618 | 8 | + | 27260156 | MHHES1 | viability | CGCTCACCGCGGGTCTCCTCCGG | RECQL4 | ENSG00000160957 | -0.7568196349036773 | [102] | [94,51,91,41] | -8 | hSpCas9 | negative selection | 7449884 | 144517807 | 144517830 | 8 | - | 27260156 | MEWO | viability | TCGCTGGACGATCGCAAGCGCGG | RECQL4 | ENSG00000160957 | 0.2917741139737231 | [87] | [98,96,105] | 6 | hSpCas9 | negative selection | 7506877 | 144517623 | 144517646 | 8 | - | 27260156 | MEWO | viability | CCCTTTACAGGACGACGTGGAGG | RECQL4 | ENSG00000160957 | -0.19000964953627697 | [255] | [262,225,150] | -4 | hSpCas9 | negative selection | 7506878 | 144517120 | 144517143 | 8 | - | 27260156 | MEWO | viability | AAGAGTCCACAGTCTACGCCAGG | RECQL4 | ENSG00000160957 | 0.2450186875538657 | [417] | [619,378,421] | 5 | hSpCas9 | negative selection | 7506879 | 144517725 | 144517748 | 8 | - | 27260156 | MEWO | viability | CGTGGGAGCGCGCGTTCCGACGG | RECQL4 | ENSG00000160957 | -0.6122220176334287 | [425] | [279,230,274] | -8 | hSpCas9 | negative selection | 7571133 | 144517075 | 144517098 | 8 | + | 27260156 | MEWO | viability | TTGAGCCGCTGCCCGTAGTCCGG | RECQL4 | ENSG00000160957 | -0.042235120908449 | [335] | [361,255,308] | -1 | hSpCas9 | negative selection | 7571134 | 144517595 | 144517618 | 8 | + | 27260156 | MEWO | viability | CGCTCACCGCGGGTCTCCTCCGG | RECQL4 | ENSG00000160957 | -0.11000582763534794 | [102] | [120,86,65] | -2 | hSpCas9 | negative selection | 7571135 | 144517807 | 144517830 | 8 | - | 27260156 | LNCAPCLONEFGC | viability | TCGCTGGACGATCGCAAGCGCGG | RECQL4 | ENSG00000160957 | 0.5636874722515512 | [87] | [128,121,112,105] | 8 | hSpCas9 | negative selection | 7628128 | 144517623 | 144517646 | 8 | - | 27260156 | LNCAPCLONEFGC | viability | CCCTTTACAGGACGACGTGGAGG | RECQL4 | ENSG00000160957 | -1.607699550573788 | [255] | [83,84,78,55] | -9 | hSpCas9 | negative selection | 7628129 | 144517120 | 144517143 | 8 | - | 27260156 | LNCAPCLONEFGC | viability | AAGAGTCCACAGTCTACGCCAGG | RECQL4 | ENSG00000160957 | 0.3623646312904998 | [417] | [381,424,689,485] | 6 | hSpCas9 | negative selection | 7628130 | 144517725 | 144517748 | 8 | - | 27260156 | LNCAPCLONEFGC | viability | CGTGGGAGCGCGCGTTCCGACGG | RECQL4 | ENSG00000160957 | -1.4696812702239737 | [425] | [137,86,120,211] | -9 | hSpCas9 | negative selection | 7692384 | 144517075 | 144517098 | 8 | + | 27260156 | LNCAPCLONEFGC | viability | TTGAGCCGCTGCCCGTAGTCCGG | RECQL4 | ENSG00000160957 | 0.18547801752571608 | [335] | [296,329,478,299] | 3 | hSpCas9 | negative selection | 7692385 | 144517595 | 144517618 | 8 | + | 27260156 | LNCAPCLONEFGC | viability | CGCTCACCGCGGGTCTCCTCCGG | RECQL4 | ENSG00000160957 | -0.7232816420079269 | [102] | [104,46,44,26] | -8 | hSpCas9 | negative selection | 7692386 | 144517807 | 144517830 | 8 | - | 27260156 | PANC0327 | viability | TCGCTGGACGATCGCAAGCGCGG | RECQL4 | ENSG00000160957 | -1.1114256983353639 | [87] | [32,39,53,16] | -8 | hSpCas9 | negative selection | 7749379 | 144517623 | 144517646 | 8 | - | 27260156 | PANC0327 | viability | CCCTTTACAGGACGACGTGGAGG | RECQL4 | ENSG00000160957 | -0.7266290869908986 | [255] | [120,100,146,183] | -7 | hSpCas9 | negative selection | 7749380 | 144517120 | 144517143 | 8 | - | 27260156 | PANC0327 | viability | AAGAGTCCACAGTCTACGCCAGG | RECQL4 | ENSG00000160957 | 0.06584236022422177 | [417] | [417,349,441,351] | 1 | hSpCas9 | negative selection | 7749381 | 144517725 | 144517748 | 8 | - | 27260156 | PANC0327 | viability | CGTGGGAGCGCGCGTTCCGACGG | RECQL4 | ENSG00000160957 | -0.8986062386091191 | [425] | [170,142,228,273] | -8 | hSpCas9 | negative selection | 7813635 | 144517075 | 144517098 | 8 | + | 27260156 | PANC0327 | viability | TTGAGCCGCTGCCCGTAGTCCGG | RECQL4 | ENSG00000160957 | 0.3235630744789605 | [335] | [423,226,410,454] | 5 | hSpCas9 | negative selection | 7813636 | 144517595 | 144517618 | 8 | + | 27260156 | PANC0327 | viability | CGCTCACCGCGGGTCTCCTCCGG | RECQL4 | ENSG00000160957 | -0.1822989501118979 | [102] | [85,56,83,98] | -3 | hSpCas9 | negative selection | 7813637 | 144517807 | 144517830 | 8 | - | 27260156 | NCIH2009 | viability | TCGCTGGACGATCGCAAGCGCGG | RECQL4 | ENSG00000160957 | 1.3200580419823487 | [87] | [190,553,147] | 9 | hSpCas9 | negative selection | 7870630 | 144517623 | 144517646 | 8 | - | 27260156 | NCIH2009 | viability | CCCTTTACAGGACGACGTGGAGG | RECQL4 | ENSG00000160957 | -0.8915913031498787 | [255] | [267,132,192] | -8 | hSpCas9 | negative selection | 7870631 | 144517120 | 144517143 | 8 | - | 27260156 | NCIH2009 | viability | AAGAGTCCACAGTCTACGCCAGG | RECQL4 | ENSG00000160957 | 0.5032485368206256 | [417] | [851,646,990] | 7 | hSpCas9 | negative selection | 7870632 | 144517725 | 144517748 | 8 | - | 27260156 | NCIH2009 | viability | CGTGGGAGCGCGCGTTCCGACGG | RECQL4 | ENSG00000160957 | -1.0416673320995933 | [425] | [341,196,339] | -8 | hSpCas9 | negative selection | 7934886 | 144517075 | 144517098 | 8 | + | 27260156 | NCIH2009 | viability | TTGAGCCGCTGCCCGTAGTCCGG | RECQL4 | ENSG00000160957 | -0.10232667331119555 | [335] | [406,556,338] | -1 | hSpCas9 | negative selection | 7934887 | 144517595 | 144517618 | 8 | + | 27260156 | NCIH2009 | viability | CGCTCACCGCGGGTCTCCTCCGG | RECQL4 | ENSG00000160957 | -0.5288697860538032 | [102] | [80,63,150] | -6 | hSpCas9 | negative selection | 7934888 | 144517807 | 144517830 | 8 | - | 27260156 | NCIH1373 | viability | TCGCTGGACGATCGCAAGCGCGG | RECQL4 | ENSG00000160957 | 0.020028068425202328 | [87] | [203,152,26,5] | 0 | hSpCas9 | negative selection | 7991881 | 144517623 | 144517646 | 8 | - | 27260156 | NCIH1373 | viability | CCCTTTACAGGACGACGTGGAGG | RECQL4 | ENSG00000160957 | -1.0685429353616995 | [255] | [143,145,140,29] | -8 | hSpCas9 | negative selection | 7991882 | 144517120 | 144517143 | 8 | - | 27260156 | NCIH1373 | viability | AAGAGTCCACAGTCTACGCCAGG | RECQL4 | ENSG00000160957 | 0.5604521482839558 | [417] | [797,768,634,146] | 5 | hSpCas9 | negative selection | 7991883 | 144517725 | 144517748 | 8 | - | 27260156 | NCIH1373 | viability | CGTGGGAGCGCGCGTTCCGACGG | RECQL4 | ENSG00000160957 | -0.7025597426037701 | [425] | [461,180,288,72] | -6 | hSpCas9 | negative selection | 8056137 | 144517075 | 144517098 | 8 | + | 27260156 | NCIH1373 | viability | TTGAGCCGCTGCCCGTAGTCCGG | RECQL4 | ENSG00000160957 | -0.021445101520183585 | [335] | [549,214,423,87] | 0 | hSpCas9 | negative selection | 8056138 | 144517595 | 144517618 | 8 | + | 27260156 | NCIH1373 | viability | CGCTCACCGCGGGTCTCCTCCGG | RECQL4 | ENSG00000160957 | -1.326484552471976 | [102] | [43,49,32,14] | -8 | hSpCas9 | negative selection | 8056139 | 144517807 | 144517830 | 8 | - | 27260156 | PATU8902 | viability | TCGCTGGACGATCGCAAGCGCGG | RECQL4 | ENSG00000160957 | -0.6369485643162176 | [87] | [33,29,10,281] | -6 | hSpCas9 | negative selection | 8113132 | 144517623 | 144517646 | 8 | - | 27260156 | PATU8902 | viability | CCCTTTACAGGACGACGTGGAGG | RECQL4 | ENSG00000160957 | -0.6065614151149848 | [255] | [304,204,230,187] | -5 | hSpCas9 | negative selection | 8113133 | 144517120 | 144517143 | 8 | - | 27260156 | PATU8902 | viability | AAGAGTCCACAGTCTACGCCAGG | RECQL4 | ENSG00000160957 | 0.37357882825159705 | [417] | [699,796,687,855] | 4 | hSpCas9 | negative selection | 8113134 | 144517725 | 144517748 | 8 | - | 27260156 | PATU8902 | viability | CGTGGGAGCGCGCGTTCCGACGG | RECQL4 | ENSG00000160957 | -1.5414510068135914 | [425] | [180,249,237,126] | -8 | hSpCas9 | negative selection | 8177388 | 144517075 | 144517098 | 8 | + | 27260156 | PATU8902 | viability | TTGAGCCGCTGCCCGTAGTCCGG | RECQL4 | ENSG00000160957 | 0.23050926535168925 | [335] | [649,648,387,544] | 2 | hSpCas9 | negative selection | 8177389 | 144517595 | 144517618 | 8 | + | 27260156 | PATU8902 | viability | CGCTCACCGCGGGTCTCCTCCGG | RECQL4 | ENSG00000160957 | -0.8688851999610359 | [102] | [34,154,31,107] | -7 | hSpCas9 | negative selection | 8177390 | 144517807 | 144517830 | 8 | - | 27260156 | PANC1 | viability | TCGCTGGACGATCGCAAGCGCGG | RECQL4 | ENSG00000160957 | -0.0009722827915497056 | [87] | [152,52,71,24] | 0 | hSpCas9 | negative selection | 8234383 | 144517623 | 144517646 | 8 | - | 27260156 | PANC1 | viability | CCCTTTACAGGACGACGTGGAGG | RECQL4 | ENSG00000160957 | -0.6391834610760535 | [255] | [131,150,182,104] | -7 | hSpCas9 | negative selection | 8234384 | 144517120 | 144517143 | 8 | - | 27260156 | PANC1 | viability | AAGAGTCCACAGTCTACGCCAGG | RECQL4 | ENSG00000160957 | 0.29432516080037874 | [417] | [432,650,312,404] | 5 | hSpCas9 | negative selection | 8234385 | 144517725 | 144517748 | 8 | - | 27260156 | PANC1 | viability | CGTGGGAGCGCGCGTTCCGACGG | RECQL4 | ENSG00000160957 | -0.8027239043335885 | [425] | [188,235,230,188] | -8 | hSpCas9 | negative selection | 8298639 | 144517075 | 144517098 | 8 | + | 27260156 | PANC1 | viability | TTGAGCCGCTGCCCGTAGTCCGG | RECQL4 | ENSG00000160957 | -0.0016139558706695367 | [335] | [253,379,261,273] | 0 | hSpCas9 | negative selection | 8298640 | 144517595 | 144517618 | 8 | + | 27260156 | PANC1 | viability | CGCTCACCGCGGGTCTCCTCCGG | RECQL4 | ENSG00000160957 | -0.1743928620639581 | [102] | [60,145,45,73] | -3 | hSpCas9 | negative selection | 8298641 | 144517807 | 144517830 | 8 | - | 27260156 | PANC0813 | viability | TCGCTGGACGATCGCAAGCGCGG | RECQL4 | ENSG00000160957 | 0.23468897544535228 | [87] | [106,164,111,101] | 4 | hSpCas9 | negative selection | 8355634 | 144517623 | 144517646 | 8 | - | 27260156 | PANC0813 | viability | CCCTTTACAGGACGACGTGGAGG | RECQL4 | ENSG00000160957 | -0.5606742542240989 | [255] | [294,130,217,180] | -7 | hSpCas9 | negative selection | 8355635 | 144517120 | 144517143 | 8 | - | 27260156 | PANC0813 | viability | AAGAGTCCACAGTCTACGCCAGG | RECQL4 | ENSG00000160957 | 0.37492050892295875 | [417] | [643,762,660,486] | 6 | hSpCas9 | negative selection | 8355636 | 144517725 | 144517748 | 8 | - | 27260156 | PANC0813 | viability | CGTGGGAGCGCGCGTTCCGACGG | RECQL4 | ENSG00000160957 | -0.7638994017991356 | [425] | [395,394,158,239] | -8 | hSpCas9 | negative selection | 8419890 | 144517075 | 144517098 | 8 | + | 27260156 | PANC0813 | viability | TTGAGCCGCTGCCCGTAGTCCGG | RECQL4 | ENSG00000160957 | -0.08003865972205898 | [335] | [419,337,413,327] | -1 | hSpCas9 | negative selection | 8419891 | 144517595 | 144517618 | 8 | + | 27260156 | PANC0813 | viability | CGCTCACCGCGGGTCTCCTCCGG | RECQL4 | ENSG00000160957 | -0.4270033658389747 | [102] | [101,109,79,69] | -6 | hSpCas9 | negative selection | 8419892 | 144517807 | 144517830 | 8 | - | 27260156 | RDES | viability | TCGCTGGACGATCGCAAGCGCGG | RECQL4 | ENSG00000160957 | 0.8157356253267605 | [87] | [241,97,213,140] | 9 | hSpCas9 | negative selection | 8476885 | 144517623 | 144517646 | 8 | - | 27260156 | RDES | viability | CCCTTTACAGGACGACGTGGAGG | RECQL4 | ENSG00000160957 | -0.23501868173053142 | [255] | [359,191,154,262] | -4 | hSpCas9 | negative selection | 8476886 | 144517120 | 144517143 | 8 | - | 27260156 | RDES | viability | AAGAGTCCACAGTCTACGCCAGG | RECQL4 | ENSG00000160957 | 0.6626415790634846 | [417] | [584,707,898,898] | 9 | hSpCas9 | negative selection | 8476887 | 144517725 | 144517748 | 8 | - | 27260156 | RDES | viability | CGTGGGAGCGCGCGTTCCGACGG | RECQL4 | ENSG00000160957 | -0.6346484669408464 | [425] | [245,311,303,421] | -8 | hSpCas9 | negative selection | 8541141 | 144517075 | 144517098 | 8 | + | 27260156 | RDES | viability | TTGAGCCGCTGCCCGTAGTCCGG | RECQL4 | ENSG00000160957 | 0.5296261197883239 | [335] | [480,450,616,718] | 8 | hSpCas9 | negative selection | 8541142 | 144517595 | 144517618 | 8 | + | 27260156 | RDES | viability | CGCTCACCGCGGGTCTCCTCCGG | RECQL4 | ENSG00000160957 | 0.1665165156274493 | [102] | [116,136,157,116] | 2 | hSpCas9 | negative selection | 8541143 | 144517807 | 144517830 | 8 | - | 27260156 | PC3 | viability | TCGCTGGACGATCGCAAGCGCGG | RECQL4 | ENSG00000160957 | 0.377722477378565 | [87] | [15,190,240,90] | 7 | hSpCas9 | negative selection | 8598136 | 144517623 | 144517646 | 8 | - | 27260156 | PC3 | viability | CCCTTTACAGGACGACGTGGAGG | RECQL4 | ENSG00000160957 | -0.5950420800557307 | [255] | [133,110,420,103] | -8 | hSpCas9 | negative selection | 8598137 | 144517120 | 144517143 | 8 | - | 27260156 | PC3 | viability | AAGAGTCCACAGTCTACGCCAGG | RECQL4 | ENSG00000160957 | 0.2669649035828 | [417] | [376,486,925,372] | 6 | hSpCas9 | negative selection | 8598138 | 144517725 | 144517748 | 8 | - | 27260156 | PC3 | viability | CGTGGGAGCGCGCGTTCCGACGG | RECQL4 | ENSG00000160957 | -0.4424844488984907 | [425] | [242,367,528,177] | -7 | hSpCas9 | negative selection | 8662392 | 144517075 | 144517098 | 8 | + | 27260156 | PC3 | viability | TTGAGCCGCTGCCCGTAGTCCGG | RECQL4 | ENSG00000160957 | 0.017736265201202916 | [335] | [259,330,451,352] | 0 | hSpCas9 | negative selection | 8662393 | 144517595 | 144517618 | 8 | + | 27260156 | PC3 | viability | CGCTCACCGCGGGTCTCCTCCGG | RECQL4 | ENSG00000160957 | 0.623942328467836 | [102] | [91,148,325,145] | 9 | hSpCas9 | negative selection | 8662394 | 144517807 | 144517830 | 8 | - | 27260156 | PATU8988T | viability | TCGCTGGACGATCGCAAGCGCGG | RECQL4 | ENSG00000160957 | -0.4357348674795509 | [87] | [60,25,92,67] | -6 | hSpCas9 | negative selection | 8719387 | 144517623 | 144517646 | 8 | - | 27260156 | PATU8988T | viability | CCCTTTACAGGACGACGTGGAGG | RECQL4 | ENSG00000160957 | -0.4042183651661527 | [255] | [89,206,229,224] | -6 | hSpCas9 | negative selection | 8719388 | 144517120 | 144517143 | 8 | - | 27260156 | PATU8988T | viability | AAGAGTCCACAGTCTACGCCAGG | RECQL4 | ENSG00000160957 | 0.11238264509551169 | [417] | [545,323,370,500] | 2 | hSpCas9 | negative selection | 8719389 | 144517725 | 144517748 | 8 | - | 27260156 | PATU8988T | viability | CGTGGGAGCGCGCGTTCCGACGG | RECQL4 | ENSG00000160957 | -0.8406296595741979 | [425] | [151,246,282,238] | -8 | hSpCas9 | negative selection | 8783643 | 144517075 | 144517098 | 8 | + | 27260156 | PATU8988T | viability | TTGAGCCGCTGCCCGTAGTCCGG | RECQL4 | ENSG00000160957 | -0.005248859607554446 | [335] | [279,417,255,351] | 0 | hSpCas9 | negative selection | 8783644 | 144517595 | 144517618 | 8 | + | 27260156 | PATU8988T | viability | CGCTCACCGCGGGTCTCCTCCGG | RECQL4 | ENSG00000160957 | 0.3040804239193693 | [102] | [104,163,99,126] | 5 | hSpCas9 | negative selection | 8783645 | 144517807 | 144517830 | 8 | - | 27260156 | T47D | viability | TCGCTGGACGATCGCAAGCGCGG | RECQL4 | ENSG00000160957 | 0.2879689484909531 | [87] | [174,80,137,109] | 6 | hSpCas9 | negative selection | 8840638 | 144517623 | 144517646 | 8 | - | 27260156 | T47D | viability | CCCTTTACAGGACGACGTGGAGG | RECQL4 | ENSG00000160957 | -0.20120712207190328 | [255] | [246,268,253,266] | -4 | hSpCas9 | negative selection | 8840639 | 144517120 | 144517143 | 8 | - | 27260156 | T47D | viability | AAGAGTCCACAGTCTACGCCAGG | RECQL4 | ENSG00000160957 | 0.3759231109685396 | [417] | [709,579,704,532] | 7 | hSpCas9 | negative selection | 8840640 | 144517725 | 144517748 | 8 | - | 27260156 | T47D | viability | CGTGGGAGCGCGCGTTCCGACGG | RECQL4 | ENSG00000160957 | -0.6507031954947183 | [425] | [342,326,239,355] | -8 | hSpCas9 | negative selection | 8904894 | 144517075 | 144517098 | 8 | + | 27260156 | T47D | viability | TTGAGCCGCTGCCCGTAGTCCGG | RECQL4 | ENSG00000160957 | 0.27601991461242636 | [335] | [479,459,539,413] | 6 | hSpCas9 | negative selection | 8904895 | 144517595 | 144517618 | 8 | + | 27260156 | T47D | viability | CGCTCACCGCGGGTCTCCTCCGG | RECQL4 | ENSG00000160957 | -0.13641487812117203 | [102] | [83,108,136,105] | -3 | hSpCas9 | negative selection | 8904896 | 144517807 | 144517830 | 8 | - | 27260156 | SU8686 | viability | TCGCTGGACGATCGCAAGCGCGG | RECQL4 | ENSG00000160957 | 0.44133245545095456 | [87] | [77,122,171,102] | 7 | hSpCas9 | negative selection | 8961889 | 144517623 | 144517646 | 8 | - | 27260156 | SU8686 | viability | CCCTTTACAGGACGACGTGGAGG | RECQL4 | ENSG00000160957 | -0.47279783423493005 | [255] | [106,186,260,185] | -6 | hSpCas9 | negative selection | 8961890 | 144517120 | 144517143 | 8 | - | 27260156 | SU8686 | viability | AAGAGTCCACAGTCTACGCCAGG | RECQL4 | ENSG00000160957 | 0.4884750466181963 | [417] | [530,503,563,767] | 7 | hSpCas9 | negative selection | 8961891 | 144517725 | 144517748 | 8 | - | 27260156 | SU8686 | viability | CGTGGGAGCGCGCGTTCCGACGG | RECQL4 | ENSG00000160957 | -0.635757977210351 | [425] | [253,281,272,277] | -7 | hSpCas9 | negative selection | 9026145 | 144517075 | 144517098 | 8 | + | 27260156 | SU8686 | viability | TTGAGCCGCTGCCCGTAGTCCGG | RECQL4 | ENSG00000160957 | -0.1569703125393786 | [335] | [232,273,384,316] | -3 | hSpCas9 | negative selection | 9026146 | 144517595 | 144517618 | 8 | + | 27260156 | SU8686 | viability | CGCTCACCGCGGGTCTCCTCCGG | RECQL4 | ENSG00000160957 | -0.2539614351457704 | [102] | [78,72,143,42] | -4 | hSpCas9 | negative selection | 9026147 | 144517807 | 144517830 | 8 | - | 27260156 | SKES1 | viability | TCGCTGGACGATCGCAAGCGCGG | RECQL4 | ENSG00000160957 | 0.165263724076965 | [87] | [106,134,80,77] | 3 | hSpCas9 | negative selection | 9083140 | 144517623 | 144517646 | 8 | - | 27260156 | SKES1 | viability | CCCTTTACAGGACGACGTGGAGG | RECQL4 | ENSG00000160957 | -0.12230228434067136 | [255] | [334,277,204,147] | -3 | hSpCas9 | negative selection | 9083141 | 144517120 | 144517143 | 8 | - | 27260156 | SKES1 | viability | AAGAGTCCACAGTCTACGCCAGG | RECQL4 | ENSG00000160957 | 0.4570836148580754 | [417] | [757,564,534,463] | 8 | hSpCas9 | negative selection | 9083142 | 144517725 | 144517748 | 8 | - | 27260156 | SKES1 | viability | CGTGGGAGCGCGCGTTCCGACGG | RECQL4 | ENSG00000160957 | 0.02871227617525421 | [425] | [618,420,306,410] | 0 | hSpCas9 | negative selection | 9147396 | 144517075 | 144517098 | 8 | + | 27260156 | SKES1 | viability | TTGAGCCGCTGCCCGTAGTCCGG | RECQL4 | ENSG00000160957 | 0.4443770119100128 | [335] | [406,403,493,495] | 8 | hSpCas9 | negative selection | 9147397 | 144517595 | 144517618 | 8 | + | 27260156 | SKES1 | viability | CGCTCACCGCGGGTCTCCTCCGG | RECQL4 | ENSG00000160957 | -0.3105709074507632 | [102] | [39,54,127,95] | -6 | hSpCas9 | negative selection | 9147398 | 144517807 | 144517830 | 8 | - | 27260156 | TOV112D | viability | TCGCTGGACGATCGCAAGCGCGG | RECQL4 | ENSG00000160957 | 0.05096313710542866 | [87] | [41,97,146,75] | 1 | hSpCas9 | negative selection | 9204391 | 144517623 | 144517646 | 8 | - | 27260156 | TOV112D | viability | CCCTTTACAGGACGACGTGGAGG | RECQL4 | ENSG00000160957 | -0.39231613861508585 | [255] | [242,270,104,184] | -7 | hSpCas9 | negative selection | 9204392 | 144517120 | 144517143 | 8 | - | 27260156 | TOV112D | viability | AAGAGTCCACAGTCTACGCCAGG | RECQL4 | ENSG00000160957 | 0.4519572603673555 | [417] | [632,1087,322,382] | 8 | hSpCas9 | negative selection | 9204393 | 144517725 | 144517748 | 8 | - | 27260156 | TOV112D | viability | CGTGGGAGCGCGCGTTCCGACGG | RECQL4 | ENSG00000160957 | -0.3521521686676228 | [425] | [251,408,282,401] | -6 | hSpCas9 | negative selection | 9268647 | 144517075 | 144517098 | 8 | + | 27260156 | TOV112D | viability | TTGAGCCGCTGCCCGTAGTCCGG | RECQL4 | ENSG00000160957 | 0.6645233844535867 | [335] | [668,418,458,567] | 9 | hSpCas9 | negative selection | 9268648 | 144517595 | 144517618 | 8 | + | 27260156 | TOV112D | viability | CGCTCACCGCGGGTCTCCTCCGG | RECQL4 | ENSG00000160957 | 0.7984380839538601 | [102] | [18,287,222,199] | 9 | hSpCas9 | negative selection | 9268649 | 144517807 | 144517830 | 8 | - | 27260156 | TC71 | viability | TCGCTGGACGATCGCAAGCGCGG | RECQL4 | ENSG00000160957 | 0.6741843270994448 | [87] | [196,131,131,139] | 9 | hSpCas9 | negative selection | 9325642 | 144517623 | 144517646 | 8 | - | 27260156 | TC71 | viability | CCCTTTACAGGACGACGTGGAGG | RECQL4 | ENSG00000160957 | -0.05637350559154708 | [255] | [288,187,266,313] | -1 | hSpCas9 | negative selection | 9325643 | 144517120 | 144517143 | 8 | - | 27260156 | TC71 | viability | AAGAGTCCACAGTCTACGCCAGG | RECQL4 | ENSG00000160957 | 0.28314540971427404 | [417] | [551,559,428,649] | 7 | hSpCas9 | negative selection | 9325644 | 144517725 | 144517748 | 8 | - | 27260156 | TC71 | viability | CGTGGGAGCGCGCGTTCCGACGG | RECQL4 | ENSG00000160957 | -0.5249471259704005 | [425] | [362,226,319,360] | -9 | hSpCas9 | negative selection | 9389898 | 144517075 | 144517098 | 8 | + | 27260156 | TC71 | viability | TTGAGCCGCTGCCCGTAGTCCGG | RECQL4 | ENSG00000160957 | 0.14523821197326864 | [335] | [418,427,352,393] | 3 | hSpCas9 | negative selection | 9389899 | 144517595 | 144517618 | 8 | + | 27260156 | TC71 | viability | CGCTCACCGCGGGTCTCCTCCGG | RECQL4 | ENSG00000160957 | 0.26675535586108823 | [102] | [148,116,131,132] | 6 | hSpCas9 | negative selection | 9389900 | 144517807 | 144517830 | 8 | - | 27260156 | TC32 | viability | TCGCTGGACGATCGCAAGCGCGG | RECQL4 | ENSG00000160957 | -0.4377593000347417 | [87] | [60,27,76,91] | -7 | hSpCas9 | negative selection | 9446893 | 144517623 | 144517646 | 8 | - | 27260156 | TC32 | viability | CCCTTTACAGGACGACGTGGAGG | RECQL4 | ENSG00000160957 | -0.6603249414061921 | [255] | [110,173,175,137] | -8 | hSpCas9 | negative selection | 9446894 | 144517120 | 144517143 | 8 | - | 27260156 | TC32 | viability | AAGAGTCCACAGTCTACGCCAGG | RECQL4 | ENSG00000160957 | 0.15226682159363475 | [417] | [389,270,575,585] | 2 | hSpCas9 | negative selection | 9446895 | 144517725 | 144517748 | 8 | - | 27260156 | TC32 | viability | CGTGGGAGCGCGCGTTCCGACGG | RECQL4 | ENSG00000160957 | -0.9252862323520397 | [425] | [204,140,310,218] | -9 | hSpCas9 | negative selection | 9511149 | 144517075 | 144517098 | 8 | + | 27260156 | TC32 | viability | TTGAGCCGCTGCCCGTAGTCCGG | RECQL4 | ENSG00000160957 | 0.3134654793050877 | [335] | [379,418,358,368] | 5 | hSpCas9 | negative selection | 9511150 | 144517595 | 144517618 | 8 | + | 27260156 | TC32 | viability | CGCTCACCGCGGGTCTCCTCCGG | RECQL4 | ENSG00000160957 | -0.23571804434652632 | [102] | [61,91,86,81] | -4 | hSpCas9 | negative selection | 9511151 | 144517119 | 144517142 | 8 | - | 28162770 | P31FUJ | viability | AGAGTCCACAGTCTACGCCAGGG | RECQL4 | ENSG00000160957 | -1.8084569629093068 | [926] | [310] | -8 | hSpCas9 | negative selection | 10223819 | 144515351 | 144515374 | 8 | + | 28162770 | P31FUJ | viability | GGAGTAGAGTGGCAGCACGGTGG | RECQL4 | ENSG00000160957 | -1.1133870374696078 | [787] | [427] | -7 | hSpCas9 | negative selection | 10223820 | 144516333 | 144516356 | 8 | - | 28162770 | P31FUJ | viability | GCAGCAGTGGAGGCGAGAAGCGG | RECQL4 | ENSG00000160957 | -2.0383945177727227 | [1635] | [467] | -8 | hSpCas9 | negative selection | 10223821 | 144516312 | 144516335 | 8 | - | 28162770 | P31FUJ | viability | GGAGATGGAACGAGGAGCCCTGG | RECQL4 | ENSG00000160957 | -0.5512072327380436 | [408] | [327] | -5 | hSpCas9 | negative selection | 10223822 | 144516175 | 144516198 | 8 | + | 28162770 | P31FUJ | viability | GATGGGCTGCTGCAGGGCTGAGG | RECQL4 | ENSG00000160957 | -0.8969349185691426 | [411] | [259] | -6 | hSpCas9 | negative selection | 10223823 | 144516067 | 144516090 | 8 | - | 28162770 | P31FUJ | viability | CGGCTGGCCCGCCATGACAGGGG | RECQL4 | ENSG00000160957 | 0.4452697006982591 | [4] | [7] | 5 | hSpCas9 | negative selection | 10223824 | 144516023 | 144516046 | 8 | - | 28162770 | P31FUJ | viability | GAAGCAGAAACACTACGTGCGGG | RECQL4 | ENSG00000160957 | -0.8647900399614221 | [1028] | [663] | -6 | hSpCas9 | negative selection | 10223825 | 144515978 | 144516001 | 8 | + | 28162770 | P31FUJ | viability | GCTGTCTTACCTGCTTGCGGAGG | RECQL4 | ENSG00000160957 | -0.23200403286379068 | [1806] | [1807] | -2 | hSpCas9 | negative selection | 10223826 | 144515860 | 144515883 | 8 | - | 28162770 | P31FUJ | viability | GCAGAAGTGGCGGAAGAAAGGGG | RECQL4 | ENSG00000160957 | -0.5734686780207086 | [2595] | [2049] | -5 | hSpCas9 | negative selection | 10223827 | 144515751 | 144515774 | 8 | + | 28162770 | P31FUJ | viability | GCAGATGTCTCACCTGGCCGGGG | RECQL4 | ENSG00000160957 | 0.5823828320656497 | [1259] | [2216] | 6 | hSpCas9 | negative selection | 10223828 | 144517119 | 144517142 | 8 | - | 28162770 | TF1 | viability | AGAGTCCACAGTCTACGCCAGGG | RECQL4 | ENSG00000160957 | NaN | [NaN] | [102] | 1 | hSpCas9 | negative selection | 10393185 | 144515351 | 144515374 | 8 | + | 28162770 | TF1 | viability | GGAGTAGAGTGGCAGCACGGTGG | RECQL4 | ENSG00000160957 | NaN | [NaN] | [44] | 1 | hSpCas9 | negative selection | 10393186 | 144516333 | 144516356 | 8 | - | 28162770 | TF1 | viability | GCAGCAGTGGAGGCGAGAAGCGG | RECQL4 | ENSG00000160957 | NaN | [NaN] | [88] | 1 | hSpCas9 | negative selection | 10393187 | 144516312 | 144516335 | 8 | - | 28162770 | TF1 | viability | GGAGATGGAACGAGGAGCCCTGG | RECQL4 | ENSG00000160957 | NaN | [NaN] | [40] | 1 | hSpCas9 | negative selection | 10393188 | 144516175 | 144516198 | 8 | + | 28162770 | TF1 | viability | GATGGGCTGCTGCAGGGCTGAGG | RECQL4 | ENSG00000160957 | NaN | [NaN] | [60] | 1 | hSpCas9 | negative selection | 10393189 | 144516067 | 144516090 | 8 | - | 28162770 | TF1 | viability | CGGCTGGCCCGCCATGACAGGGG | RECQL4 | ENSG00000160957 | NaN | [NaN] | [1] | 1 | hSpCas9 | negative selection | 10393190 | 144516023 | 144516046 | 8 | - | 28162770 | TF1 | viability | GAAGCAGAAACACTACGTGCGGG | RECQL4 | ENSG00000160957 | NaN | [NaN] | [115] | 1 | hSpCas9 | negative selection | 10393191 | 144515978 | 144516001 | 8 | + | 28162770 | TF1 | viability | GCTGTCTTACCTGCTTGCGGAGG | RECQL4 | ENSG00000160957 | NaN | [NaN] | [155] | 1 | hSpCas9 | negative selection | 10393192 | 144515860 | 144515883 | 8 | - | 28162770 | TF1 | viability | GCAGAAGTGGCGGAAGAAAGGGG | RECQL4 | ENSG00000160957 | NaN | [NaN] | [248] | 1 | hSpCas9 | negative selection | 10393193 | 144515751 | 144515774 | 8 | + | 28162770 | TF1 | viability | GCAGATGTCTCACCTGGCCGGGG | RECQL4 | ENSG00000160957 | NaN | [NaN] | [260] | 1 | hSpCas9 | negative selection | 10393194 | 144517119 | 144517142 | 8 | - | 28162770 | SKM1 | viability | AGAGTCCACAGTCTACGCCAGGG | RECQL4 | ENSG00000160957 | -0.718908205057902 | [53] | [57] | -5 | hSpCas9 | negative selection | 10562551 | 144515351 | 144515374 | 8 | + | 28162770 | SKM1 | viability | GGAGTAGAGTGGCAGCACGGTGG | RECQL4 | ENSG00000160957 | -0.8960022794657823 | [59] | [56] | -6 | hSpCas9 | negative selection | 10562552 | 144516333 | 144516356 | 8 | - | 28162770 | SKM1 | viability | GCAGCAGTGGAGGCGAGAAGCGG | RECQL4 | ENSG00000160957 | -1.7665065854303017 | [101] | [52] | -8 | hSpCas9 | negative selection | 10562553 | 144516312 | 144516335 | 8 | - | 28162770 | SKM1 | viability | GGAGATGGAACGAGGAGCCCTGG | RECQL4 | ENSG00000160957 | 0.3200173068504224 | [28] | [63] | 3 | hSpCas9 | negative selection | 10562554 | 144516175 | 144516198 | 8 | + | 28162770 | SKM1 | viability | GATGGGCTGCTGCAGGGCTGAGG | RECQL4 | ENSG00000160957 | -0.17430344195288672 | [29] | [46] | -1 | hSpCas9 | negative selection | 10562555 | 144516067 | 144516090 | 8 | - | 28162770 | SKM1 | viability | CGGCTGGCCCGCCATGACAGGGG | RECQL4 | ENSG00000160957 | -0.8220016980220048 | [0] | [0] | -6 | hSpCas9 | negative selection | 10562556 | 144516023 | 144516046 | 8 | - | 28162770 | SKM1 | viability | GAAGCAGAAACACTACGTGCGGG | RECQL4 | ENSG00000160957 | -0.3297963382207017 | [90] | [127] | -3 | hSpCas9 | negative selection | 10562557 | 144515978 | 144516001 | 8 | + | 28162770 | SKM1 | viability | GCTGTCTTACCTGCTTGCGGAGG | RECQL4 | ENSG00000160957 | 0.0524674198941355 | [107] | [197] | 0 | hSpCas9 | negative selection | 10562558 | 144515860 | 144515883 | 8 | - | 28162770 | SKM1 | viability | GCAGAAGTGGCGGAAGAAAGGGG | RECQL4 | ENSG00000160957 | -0.33792255431351026 | [152] | [213] | -3 | hSpCas9 | negative selection | 10562559 | 144515751 | 144515774 | 8 | + | 28162770 | SKM1 | viability | GCAGATGTCTCACCTGGCCGGGG | RECQL4 | ENSG00000160957 | 0.5451151706316122 | [87] | [226] | 5 | hSpCas9 | negative selection | 10562560 | 144517119 | 144517142 | 8 | - | 28162770 | SKM1 | viability | AGAGTCCACAGTCTACGCCAGGG | RECQL4 | ENSG00000160957 | -0.718908205057902 | [53] | [57] | -5 | hSpCas9 | negative selection | 10731917 | 144515351 | 144515374 | 8 | + | 28162770 | SKM1 | viability | GGAGTAGAGTGGCAGCACGGTGG | RECQL4 | ENSG00000160957 | -0.8960022794657823 | [59] | [56] | -6 | hSpCas9 | negative selection | 10731918 | 144516333 | 144516356 | 8 | - | 28162770 | SKM1 | viability | GCAGCAGTGGAGGCGAGAAGCGG | RECQL4 | ENSG00000160957 | -1.7665065854303017 | [101] | [52] | -8 | hSpCas9 | negative selection | 10731919 | 144516312 | 144516335 | 8 | - | 28162770 | SKM1 | viability | GGAGATGGAACGAGGAGCCCTGG | RECQL4 | ENSG00000160957 | 0.3200173068504224 | [28] | [63] | 3 | hSpCas9 | negative selection | 10731920 | 144516175 | 144516198 | 8 | + | 28162770 | SKM1 | viability | GATGGGCTGCTGCAGGGCTGAGG | RECQL4 | ENSG00000160957 | -0.17430344195288672 | [29] | [46] | -1 | hSpCas9 | negative selection | 10731921 | 144516067 | 144516090 | 8 | - | 28162770 | SKM1 | viability | CGGCTGGCCCGCCATGACAGGGG | RECQL4 | ENSG00000160957 | -0.8220016980220048 | [0] | [0] | -6 | hSpCas9 | negative selection | 10731922 | 144516023 | 144516046 | 8 | - | 28162770 | SKM1 | viability | GAAGCAGAAACACTACGTGCGGG | RECQL4 | ENSG00000160957 | -0.3297963382207017 | [90] | [127] | -3 | hSpCas9 | negative selection | 10731923 | 144515978 | 144516001 | 8 | + | 28162770 | SKM1 | viability | GCTGTCTTACCTGCTTGCGGAGG | RECQL4 | ENSG00000160957 | 0.0524674198941355 | [107] | [197] | 0 | hSpCas9 | negative selection | 10731924 | 144515860 | 144515883 | 8 | - | 28162770 | SKM1 | viability | GCAGAAGTGGCGGAAGAAAGGGG | RECQL4 | ENSG00000160957 | -0.33792255431351026 | [152] | [213] | -3 | hSpCas9 | negative selection | 10731925 | 144515751 | 144515774 | 8 | + | 28162770 | SKM1 | viability | GCAGATGTCTCACCTGGCCGGGG | RECQL4 | ENSG00000160957 | 0.5451151706316122 | [87] | [226] | 5 | hSpCas9 | negative selection | 10731926 | 144517119 | 144517142 | 8 | - | 28162770 | PL21 | viability | AGAGTCCACAGTCTACGCCAGGG | RECQL4 | ENSG00000160957 | 0.5078738277939282 | [285] | [176] | 4 | hSpCas9 | negative selection | 10901283 | 144515351 | 144515374 | 8 | + | 28162770 | PL21 | viability | GGAGTAGAGTGGCAGCACGGTGG | RECQL4 | ENSG00000160957 | -0.9901915976148292 | [177] | [38] | -6 | hSpCas9 | negative selection | 10901284 | 144516333 | 144516356 | 8 | - | 28162770 | PL21 | viability | GCAGCAGTGGAGGCGAGAAGCGG | RECQL4 | ENSG00000160957 | -1.4170632232320441 | [361] | [58] | -7 | hSpCas9 | negative selection | 10901285 | 144516312 | 144516335 | 8 | - | 28162770 | PL21 | viability | GGAGATGGAACGAGGAGCCCTGG | RECQL4 | ENSG00000160957 | 0.017936283268571218 | [117] | [51] | 0 | hSpCas9 | negative selection | 10901286 | 144516175 | 144516198 | 8 | + | 28162770 | PL21 | viability | GATGGGCTGCTGCAGGGCTGAGG | RECQL4 | ENSG00000160957 | -0.05765814297832661 | [109] | [45] | 0 | hSpCas9 | negative selection | 10901287 | 144516067 | 144516090 | 8 | - | 28162770 | PL21 | viability | CGGCTGGCCCGCCATGACAGGGG | RECQL4 | ENSG00000160957 | 1.20013961448932 | [0] | [0] | 8 | hSpCas9 | negative selection | 10901288 | 144516023 | 144516046 | 8 | - | 28162770 | PL21 | viability | GAAGCAGAAACACTACGTGCGGG | RECQL4 | ENSG00000160957 | -0.6703496525142756 | [361] | [98] | -5 | hSpCas9 | negative selection | 10901289 | 144515978 | 144516001 | 8 | + | 28162770 | PL21 | viability | GCTGTCTTACCTGCTTGCGGAGG | RECQL4 | ENSG00000160957 | 0.2657279561168968 | [429] | [224] | 2 | hSpCas9 | negative selection | 10901290 | 144515860 | 144515883 | 8 | - | 28162770 | PL21 | viability | GCAGAAGTGGCGGAAGAAAGGGG | RECQL4 | ENSG00000160957 | -0.6167380816867906 | [531] | [150] | -4 | hSpCas9 | negative selection | 10901291 | 144515751 | 144515774 | 8 | + | 28162770 | PL21 | viability | GCAGATGTCTCACCTGGCCGGGG | RECQL4 | ENSG00000160957 | 0.7167151402302263 | [287] | [205] | 6 | hSpCas9 | negative selection | 10901292 | 144517119 | 144517142 | 8 | - | 28162770 | P31FUJ | viability | AGAGTCCACAGTCTACGCCAGGG | RECQL4 | ENSG00000160957 | -1.8084569629093068 | [926] | [310] | -8 | hSpCas9 | negative selection | 11070649 | 144515351 | 144515374 | 8 | + | 28162770 | P31FUJ | viability | GGAGTAGAGTGGCAGCACGGTGG | RECQL4 | ENSG00000160957 | -1.1133870374696078 | [787] | [427] | -7 | hSpCas9 | negative selection | 11070650 | 144516333 | 144516356 | 8 | - | 28162770 | P31FUJ | viability | GCAGCAGTGGAGGCGAGAAGCGG | RECQL4 | ENSG00000160957 | -2.0383945177727227 | [1635] | [467] | -8 | hSpCas9 | negative selection | 11070651 | 144516312 | 144516335 | 8 | - | 28162770 | P31FUJ | viability | GGAGATGGAACGAGGAGCCCTGG | RECQL4 | ENSG00000160957 | -0.5512072327380436 | [408] | [327] | -5 | hSpCas9 | negative selection | 11070652 | 144516175 | 144516198 | 8 | + | 28162770 | P31FUJ | viability | GATGGGCTGCTGCAGGGCTGAGG | RECQL4 | ENSG00000160957 | -0.8969349185691426 | [411] | [259] | -6 | hSpCas9 | negative selection | 11070653 | 144516067 | 144516090 | 8 | - | 28162770 | P31FUJ | viability | CGGCTGGCCCGCCATGACAGGGG | RECQL4 | ENSG00000160957 | 0.4452697006982591 | [4] | [7] | 5 | hSpCas9 | negative selection | 11070654 | 144516023 | 144516046 | 8 | - | 28162770 | P31FUJ | viability | GAAGCAGAAACACTACGTGCGGG | RECQL4 | ENSG00000160957 | -0.8647900399614221 | [1028] | [663] | -6 | hSpCas9 | negative selection | 11070655 | 144515978 | 144516001 | 8 | + | 28162770 | P31FUJ | viability | GCTGTCTTACCTGCTTGCGGAGG | RECQL4 | ENSG00000160957 | -0.23200403286379068 | [1806] | [1807] | -2 | hSpCas9 | negative selection | 11070656 | 144515860 | 144515883 | 8 | - | 28162770 | P31FUJ | viability | GCAGAAGTGGCGGAAGAAAGGGG | RECQL4 | ENSG00000160957 | -0.5734686780207086 | [2595] | [2049] | -5 | hSpCas9 | negative selection | 11070657 | 144515751 | 144515774 | 8 | + | 28162770 | P31FUJ | viability | GCAGATGTCTCACCTGGCCGGGG | RECQL4 | ENSG00000160957 | 0.5823828320656497 | [1259] | [2216] | 6 | hSpCas9 | negative selection | 11070658 | 144517119 | 144517142 | 8 | - | 28162770 | OCIAML5 | viability | AGAGTCCACAGTCTACGCCAGGG | RECQL4 | ENSG00000160957 | -2.4507040084822296 | [105] | [34] | -8 | hSpCas9 | negative selection | 11240015 | 144515351 | 144515374 | 8 | + | 28162770 | OCIAML5 | viability | GGAGTAGAGTGGCAGCACGGTGG | RECQL4 | ENSG00000160957 | -0.5573233053028648 | [74] | [91] | -4 | hSpCas9 | negative selection | 11240016 | 144516333 | 144516356 | 8 | - | 28162770 | OCIAML5 | viability | GCAGCAGTGGAGGCGAGAAGCGG | RECQL4 | ENSG00000160957 | -3.35668696326755 | [226] | [39] | -9 | hSpCas9 | negative selection | 11240017 | 144516312 | 144516335 | 8 | - | 28162770 | OCIAML5 | viability | GGAGATGGAACGAGGAGCCCTGG | RECQL4 | ENSG00000160957 | 0.8234984786380658 | [35] | [114] | 7 | hSpCas9 | negative selection | 11240018 | 144516175 | 144516198 | 8 | + | 28162770 | OCIAML5 | viability | GATGGGCTGCTGCAGGGCTGAGG | RECQL4 | ENSG00000160957 | -1.6472467789754988 | [58] | [33] | -7 | hSpCas9 | negative selection | 11240019 | 144516067 | 144516090 | 8 | - | 28162770 | OCIAML5 | viability | CGGCTGGCCCGCCATGACAGGGG | RECQL4 | ENSG00000160957 | -1.8520665708639967 | [25] | [12] | -7 | hSpCas9 | negative selection | 11240020 | 144516023 | 144516046 | 8 | - | 28162770 | OCIAML5 | viability | GAAGCAGAAACACTACGTGCGGG | RECQL4 | ENSG00000160957 | -2.0340069484631504 | [210] | [92] | -8 | hSpCas9 | negative selection | 11240021 | 144515978 | 144516001 | 8 | + | 28162770 | OCIAML5 | viability | GCTGTCTTACCTGCTTGCGGAGG | RECQL4 | ENSG00000160957 | -0.9829140503236187 | [172] | [157] | -6 | hSpCas9 | negative selection | 11240022 | 144515860 | 144515883 | 8 | - | 28162770 | OCIAML5 | viability | GCAGAAGTGGCGGAAGAAAGGGG | RECQL4 | ENSG00000160957 | -0.6594214929216011 | [251] | [287] | -4 | hSpCas9 | negative selection | 11240023 | 144515751 | 144515774 | 8 | + | 28162770 | OCIAML5 | viability | GCAGATGTCTCACCTGGCCGGGG | RECQL4 | ENSG00000160957 | 1.107615973948515 | [126] | [493] | 8 | hSpCas9 | negative selection | 11240024 | 144517119 | 144517142 | 8 | - | 28162770 | EOL1 | viability | AGAGTCCACAGTCTACGCCAGGG | RECQL4 | ENSG00000160957 | -1.3406577333048866 | [398] | [82] | -7 | hSpCas9 | negative selection | 11409381 | 144515351 | 144515374 | 8 | + | 28162770 | EOL1 | viability | GGAGTAGAGTGGCAGCACGGTGG | RECQL4 | ENSG00000160957 | -0.7144914019064144 | [298] | [95] | -5 | hSpCas9 | negative selection | 11409382 | 144516333 | 144516356 | 8 | - | 28162770 | EOL1 | viability | GCAGCAGTGGAGGCGAGAAGCGG | RECQL4 | ENSG00000160957 | -1.411879893011943 | [499] | [98] | -7 | hSpCas9 | negative selection | 11409383 | 144516312 | 144516335 | 8 | - | 28162770 | EOL1 | viability | GGAGATGGAACGAGGAGCCCTGG | RECQL4 | ENSG00000160957 | -0.09213096957609601 | [173] | [85] | 0 | hSpCas9 | negative selection | 11409384 | 144516175 | 144516198 | 8 | + | 28162770 | EOL1 | viability | GATGGGCTGCTGCAGGGCTGAGG | RECQL4 | ENSG00000160957 | -0.7687908901954137 | [151] | [46] | -5 | hSpCas9 | negative selection | 11409385 | 144516067 | 144516090 | 8 | - | 28162770 | EOL1 | viability | CGGCTGGCCCGCCATGACAGGGG | RECQL4 | ENSG00000160957 | 0.18758217740432848 | [4] | [2] | 1 | hSpCas9 | negative selection | 11409386 | 144516023 | 144516046 | 8 | - | 28162770 | EOL1 | viability | GAAGCAGAAACACTACGTGCGGG | RECQL4 | ENSG00000160957 | -2.108875229966916 | [392] | [47] | -8 | hSpCas9 | negative selection | 11409387 | 144515978 | 144516001 | 8 | + | 28162770 | EOL1 | viability | GCTGTCTTACCTGCTTGCGGAGG | RECQL4 | ENSG00000160957 | -0.5585351151314082 | [614] | [219] | -4 | hSpCas9 | negative selection | 11409388 | 144515860 | 144515883 | 8 | - | 28162770 | EOL1 | viability | GCAGAAGTGGCGGAAGAAAGGGG | RECQL4 | ENSG00000160957 | -0.2182528288284895 | [763] | [345] | -2 | hSpCas9 | negative selection | 11409389 | 144515751 | 144515774 | 8 | + | 28162770 | EOL1 | viability | GCAGATGTCTCACCTGGCCGGGG | RECQL4 | ENSG00000160957 | -0.3973803233168278 | [364] | [145] | -3 | hSpCas9 | negative selection | 11409390 | 144517119 | 144517142 | 8 | - | 28162770 | MOLM13 | viability | AGAGTCCACAGTCTACGCCAGGG | RECQL4 | ENSG00000160957 | -1.3455743500956707 | [354] | [100] | -6 | hSpCas9 | negative selection | 11578747 | 144515351 | 144515374 | 8 | + | 28162770 | MOLM13 | viability | GGAGTAGAGTGGCAGCACGGTGG | RECQL4 | ENSG00000160957 | -0.5606797706521921 | [152] | [74] | -3 | hSpCas9 | negative selection | 11578748 | 144516333 | 144516356 | 8 | - | 28162770 | MOLM13 | viability | GCAGCAGTGGAGGCGAGAAGCGG | RECQL4 | ENSG00000160957 | -1.6719335881083146 | [497] | [112] | -7 | hSpCas9 | negative selection | 11578749 | 144516312 | 144516335 | 8 | - | 28162770 | MOLM13 | viability | GGAGATGGAACGAGGAGCCCTGG | RECQL4 | ENSG00000160957 | 0.6507534386943892 | [147] | [167] | 5 | hSpCas9 | negative selection | 11578750 | 144516175 | 144516198 | 8 | + | 28162770 | MOLM13 | viability | GATGGGCTGCTGCAGGGCTGAGG | RECQL4 | ENSG00000160957 | -3.684113711900471 | [159] | [8] | -9 | hSpCas9 | negative selection | 11578751 | 144516067 | 144516090 | 8 | - | 28162770 | MOLM13 | viability | CGGCTGGCCCGCCATGACAGGGG | RECQL4 | ENSG00000160957 | -4.7415639840843715 | [36] | [0] | -9 | hSpCas9 | negative selection | 11578752 | 144516023 | 144516046 | 8 | - | 28162770 | MOLM13 | viability | GAAGCAGAAACACTACGTGCGGG | RECQL4 | ENSG00000160957 | -1.7383110062892835 | [442] | [95] | -7 | hSpCas9 | negative selection | 11578753 | 144515978 | 144516001 | 8 | + | 28162770 | MOLM13 | viability | GCTGTCTTACCTGCTTGCGGAGG | RECQL4 | ENSG00000160957 | -0.8990156220611675 | [618] | [239] | -5 | hSpCas9 | negative selection | 11578754 | 144515860 | 144515883 | 8 | - | 28162770 | MOLM13 | viability | GCAGAAGTGGCGGAAGAAAGGGG | RECQL4 | ENSG00000160957 | -1.2041298534458007 | [665] | [208] | -6 | hSpCas9 | negative selection | 11578755 | 144515751 | 144515774 | 8 | + | 28162770 | MOLM13 | viability | GCAGATGTCTCACCTGGCCGGGG | RECQL4 | ENSG00000160957 | -0.21525351311548074 | [341] | [212] | -1 | hSpCas9 | negative selection | 11578756 | 144517119 | 144517142 | 8 | - | 28162770 | HEL | viability | AGAGTCCACAGTCTACGCCAGGG | RECQL4 | ENSG00000160957 | 1.4790496323542213 | [302] | [540] | 9 | hSpCas9 | negative selection | 11748113 | 144515351 | 144515374 | 8 | + | 28162770 | HEL | viability | GGAGTAGAGTGGCAGCACGGTGG | RECQL4 | ENSG00000160957 | 0.08292980850753898 | [198] | [134] | 0 | hSpCas9 | negative selection | 11748114 | 144516333 | 144516356 | 8 | - | 28162770 | HEL | viability | GCAGCAGTGGAGGCGAGAAGCGG | RECQL4 | ENSG00000160957 | -0.8305132812237827 | [471] | [169] | -5 | hSpCas9 | negative selection | 11748115 | 144516312 | 144516335 | 8 | - | 28162770 | HEL | viability | GGAGATGGAACGAGGAGCCCTGG | RECQL4 | ENSG00000160957 | 0.8749122741293902 | [125] | [147] | 7 | hSpCas9 | negative selection | 11748116 | 144516175 | 144516198 | 8 | + | 28162770 | HEL | viability | GATGGGCTGCTGCAGGGCTGAGG | RECQL4 | ENSG00000160957 | 0.9364700350570673 | [92] | [113] | 7 | hSpCas9 | negative selection | 11748117 | 144516067 | 144516090 | 8 | - | 28162770 | HEL | viability | CGGCTGGCCCGCCATGACAGGGG | RECQL4 | ENSG00000160957 | -2.12279591436262 | [33] | [4] | -8 | hSpCas9 | negative selection | 11748118 | 144516023 | 144516046 | 8 | - | 28162770 | HEL | viability | GAAGCAGAAACACTACGTGCGGG | RECQL4 | ENSG00000160957 | 0.5717723106462133 | [374] | [356] | 5 | hSpCas9 | negative selection | 11748119 | 144515978 | 144516001 | 8 | + | 28162770 | HEL | viability | GCTGTCTTACCTGCTTGCGGAGG | RECQL4 | ENSG00000160957 | -0.29489528703926937 | [497] | [259] | -2 | hSpCas9 | negative selection | 11748120 | 144515860 | 144515883 | 8 | - | 28162770 | HEL | viability | GCAGAAGTGGCGGAAGAAAGGGG | RECQL4 | ENSG00000160957 | -0.31637669336963303 | [660] | [339] | -2 | hSpCas9 | negative selection | 11748121 | 144515751 | 144515774 | 8 | + | 28162770 | HEL | viability | GCAGATGTCTCACCTGGCCGGGG | RECQL4 | ENSG00000160957 | 0.8742622650889331 | [269] | [316] | 7 | hSpCas9 | negative selection | 11748122 | 144517119 | 144517142 | 8 | - | 28162770 | MV411 | viability | AGAGTCCACAGTCTACGCCAGGG | RECQL4 | ENSG00000160957 | -1.3854196400426924 | [244] | [78] | -7 | hSpCas9 | negative selection | 11917479 | 144515351 | 144515374 | 8 | + | 28162770 | MV411 | viability | GGAGTAGAGTGGCAGCACGGTGG | RECQL4 | ENSG00000160957 | -1.048018332743396 | [188] | [76] | -6 | hSpCas9 | negative selection | 11917480 | 144516333 | 144516356 | 8 | - | 28162770 | MV411 | viability | GCAGCAGTGGAGGCGAGAAGCGG | RECQL4 | ENSG00000160957 | -2.2793103359930855 | [339] | [58] | -8 | hSpCas9 | negative selection | 11917481 | 144516312 | 144516335 | 8 | - | 28162770 | MV411 | viability | GGAGATGGAACGAGGAGCCCTGG | RECQL4 | ENSG00000160957 | -0.3095105737687842 | [152] | [103] | -2 | hSpCas9 | negative selection | 11917482 | 144516175 | 144516198 | 8 | + | 28162770 | MV411 | viability | GATGGGCTGCTGCAGGGCTGAGG | RECQL4 | ENSG00000160957 | -0.20507465391473134 | [129] | [94] | -1 | hSpCas9 | negative selection | 11917483 | 144516067 | 144516090 | 8 | - | 28162770 | MV411 | viability | CGGCTGGCCCGCCATGACAGGGG | RECQL4 | ENSG00000160957 | 0.6624750500616194 | [2] | [3] | 6 | hSpCas9 | negative selection | 11917484 | 144516023 | 144516046 | 8 | - | 28162770 | MV411 | viability | GAAGCAGAAACACTACGTGCGGG | RECQL4 | ENSG00000160957 | -0.82513107516787 | [264] | [125] | -5 | hSpCas9 | negative selection | 11917485 | 144515978 | 144516001 | 8 | + | 28162770 | MV411 | viability | GCTGTCTTACCTGCTTGCGGAGG | RECQL4 | ENSG00000160957 | -0.7697171702562915 | [422] | [208] | -5 | hSpCas9 | negative selection | 11917486 | 144515860 | 144515883 | 8 | - | 28162770 | MV411 | viability | GCAGAAGTGGCGGAAGAAAGGGG | RECQL4 | ENSG00000160957 | -1.2522971130713498 | [607] | [214] | -7 | hSpCas9 | negative selection | 11917487 | 144515751 | 144515774 | 8 | + | 28162770 | MV411 | viability | GCAGATGTCTCACCTGGCCGGGG | RECQL4 | ENSG00000160957 | 1.0792522035255594 | [258] | [460] | 8 | hSpCas9 | negative selection | 11917488 | 144517119 | 144517142 | 8 | - | 28162770 | MONOMAC1 | viability | AGAGTCCACAGTCTACGCCAGGG | RECQL4 | ENSG00000160957 | -1.3884629177127883 | [168] | [73] | -8 | hSpCas9 | negative selection | 12086845 | 144515351 | 144515374 | 8 | + | 28162770 | MONOMAC1 | viability | GGAGTAGAGTGGCAGCACGGTGG | RECQL4 | ENSG00000160957 | 0.35420503581760127 | [100] | [147] | 3 | hSpCas9 | negative selection | 12086846 | 144516333 | 144516356 | 8 | - | 28162770 | MONOMAC1 | viability | GCAGCAGTGGAGGCGAGAAGCGG | RECQL4 | ENSG00000160957 | -0.8952700467370452 | [244] | [150] | -6 | hSpCas9 | negative selection | 12086847 | 144516312 | 144516335 | 8 | - | 28162770 | MONOMAC1 | viability | GGAGATGGAACGAGGAGCCCTGG | RECQL4 | ENSG00000160957 | -0.39448291126577084 | [85] | [74] | -3 | hSpCas9 | negative selection | 12086848 | 144516175 | 144516198 | 8 | + | 28162770 | MONOMAC1 | viability | GATGGGCTGCTGCAGGGCTGAGG | RECQL4 | ENSG00000160957 | -0.8858351587652497 | [107] | [66] | -6 | hSpCas9 | negative selection | 12086849 | 144516067 | 144516090 | 8 | - | 28162770 | MONOMAC1 | viability | CGGCTGGCCCGCCATGACAGGGG | RECQL4 | ENSG00000160957 | -0.19703684705955382 | [0] | [0] | -2 | hSpCas9 | negative selection | 12086850 | 144516023 | 144516046 | 8 | - | 28162770 | MONOMAC1 | viability | GAAGCAGAAACACTACGTGCGGG | RECQL4 | ENSG00000160957 | -0.520926458280202 | [183] | [146] | -4 | hSpCas9 | negative selection | 12086851 | 144515978 | 144516001 | 8 | + | 28162770 | MONOMAC1 | viability | GCTGTCTTACCTGCTTGCGGAGG | RECQL4 | ENSG00000160957 | 0.15456211450415136 | [307] | [392] | 1 | hSpCas9 | negative selection | 12086852 | 144515860 | 144515883 | 8 | - | 28162770 | MONOMAC1 | viability | GCAGAAGTGGCGGAAGAAAGGGG | RECQL4 | ENSG00000160957 | -0.7461986263528632 | [397] | [271] | -6 | hSpCas9 | negative selection | 12086853 | 144515751 | 144515774 | 8 | + | 28162770 | MONOMAC1 | viability | GCAGATGTCTCACCTGGCCGGGG | RECQL4 | ENSG00000160957 | 0.4281147437773013 | [176] | [272] | 4 | hSpCas9 | negative selection | 12086854 | 144517119 | 144517142 | 8 | - | 28162770 | OCIAML2 | viability | AGAGTCCACAGTCTACGCCAGGG | RECQL4 | ENSG00000160957 | -1.1710695433832534 | [51] | [127] | -6 | hSpCas9 | negative selection | 12256211 | 144515351 | 144515374 | 8 | + | 28162770 | OCIAML2 | viability | GGAGTAGAGTGGCAGCACGGTGG | RECQL4 | ENSG00000160957 | -0.10289804074167411 | [30] | [159] | -1 | hSpCas9 | negative selection | 12256212 | 144516333 | 144516356 | 8 | - | 28162770 | OCIAML2 | viability | GCAGCAGTGGAGGCGAGAAGCGG | RECQL4 | ENSG00000160957 | -1.6770807027095875 | [74] | [129] | -7 | hSpCas9 | negative selection | 12256213 | 144516312 | 144516335 | 8 | - | 28162770 | OCIAML2 | viability | GGAGATGGAACGAGGAGCCCTGG | RECQL4 | ENSG00000160957 | 0.12474929142433339 | [22] | [138] | 1 | hSpCas9 | negative selection | 12256214 | 144516175 | 144516198 | 8 | + | 28162770 | OCIAML2 | viability | GATGGGCTGCTGCAGGGCTGAGG | RECQL4 | ENSG00000160957 | 0.04594570049874491 | [17] | [102] | 0 | hSpCas9 | negative selection | 12256215 | 144516067 | 144516090 | 8 | - | 28162770 | OCIAML2 | viability | CGGCTGGCCCGCCATGACAGGGG | RECQL4 | ENSG00000160957 | -0.8856673245210054 | [0] | [2] | -6 | hSpCas9 | negative selection | 12256216 | 144516023 | 144516046 | 8 | - | 28162770 | OCIAML2 | viability | GAAGCAGAAACACTACGTGCGGG | RECQL4 | ENSG00000160957 | -0.699571032407547 | [45] | [156] | -5 | hSpCas9 | negative selection | 12256217 | 144515978 | 144516001 | 8 | + | 28162770 | OCIAML2 | viability | GCTGTCTTACCTGCTTGCGGAGG | RECQL4 | ENSG00000160957 | -0.6632749031845572 | [87] | [307] | -5 | hSpCas9 | negative selection | 12256218 | 144515860 | 144515883 | 8 | - | 28162770 | OCIAML2 | viability | GCAGAAGTGGCGGAAGAAAGGGG | RECQL4 | ENSG00000160957 | -0.6944429212782364 | [126] | [434] | -5 | hSpCas9 | negative selection | 12256219 | 144515751 | 144515774 | 8 | + | 28162770 | OCIAML2 | viability | GCAGATGTCTCACCTGGCCGGGG | RECQL4 | ENSG00000160957 | 0.266335768924045 | [56] | [379] | 2 | hSpCas9 | negative selection | 12256220 | 144517119 | 144517142 | 8 | - | 28162770 | OCIAML3 | viability | AGAGTCCACAGTCTACGCCAGGG | RECQL4 | ENSG00000160957 | -1.2364556357060794 | [63] | [81] | -7 | hSpCas9 | negative selection | 12425577 | 144515351 | 144515374 | 8 | + | 28162770 | OCIAML3 | viability | GGAGTAGAGTGGCAGCACGGTGG | RECQL4 | ENSG00000160957 | -0.8640968036919077 | [40] | [67] | -6 | hSpCas9 | negative selection | 12425578 | 144516333 | 144516356 | 8 | - | 28162770 | OCIAML3 | viability | GCAGCAGTGGAGGCGAGAAGCGG | RECQL4 | ENSG00000160957 | -1.4206760374386014 | [93] | [105] | -7 | hSpCas9 | negative selection | 12425579 | 144516312 | 144516335 | 8 | - | 28162770 | OCIAML3 | viability | GGAGATGGAACGAGGAGCCCTGG | RECQL4 | ENSG00000160957 | 0.8522485895654008 | [19] | [108] | 7 | hSpCas9 | negative selection | 12425580 | 144516175 | 144516198 | 8 | + | 28162770 | OCIAML3 | viability | GATGGGCTGCTGCAGGGCTGAGG | RECQL4 | ENSG00000160957 | -0.7113645909623219 | [31] | [58] | -5 | hSpCas9 | negative selection | 12425581 | 144516067 | 144516090 | 8 | - | 28162770 | OCIAML3 | viability | CGGCTGGCCCGCCATGACAGGGG | RECQL4 | ENSG00000160957 | -1.594007640324163 | [0] | [0] | -8 | hSpCas9 | negative selection | 12425582 | 144516023 | 144516046 | 8 | - | 28162770 | OCIAML3 | viability | GAAGCAGAAACACTACGTGCGGG | RECQL4 | ENSG00000160957 | 0.5325247656047686 | [59] | [261] | 5 | hSpCas9 | negative selection | 12425583 | 144515978 | 144516001 | 8 | + | 28162770 | OCIAML3 | viability | GCTGTCTTACCTGCTTGCGGAGG | RECQL4 | ENSG00000160957 | -0.12007645199175088 | [98] | [274] | -1 | hSpCas9 | negative selection | 12425584 | 144515860 | 144515883 | 8 | - | 28162770 | OCIAML3 | viability | GCAGAAGTGGCGGAAGAAAGGGG | RECQL4 | ENSG00000160957 | -0.6089065167035016 | [145] | [288] | -5 | hSpCas9 | negative selection | 12425585 | 144515751 | 144515774 | 8 | + | 28162770 | OCIAML3 | viability | GCAGATGTCTCACCTGGCCGGGG | RECQL4 | ENSG00000160957 | 1.1791585955576143 | [60] | [416] | 8 | hSpCas9 | negative selection | 12425586 |