| 675777 | 675800 | 16 | + | 26627737 | DLD1 | viability | CCCGGCCAGGCTCTATGGACAGG | RHBDL1 | ENSG00000103269 | 0.06442915391363702 | [931] | [338,167,387] | 0 | hSpCas9 | negative selection | 795318 | 676443 | 676466 | 16 | + | 26627737 | DLD1 | viability | CCTGGCTCAGAGCAACGAGCAGG | RHBDL1 | ENSG00000103269 | 0.08116947289638976 | [283] | [23,137,117] | 0 | hSpCas9 | negative selection | 795319 | 676824 | 676847 | 16 | - | 26627737 | DLD1 | viability | GACGGTAGAAGTACCAGCGGCGG | RHBDL1 | ENSG00000103269 | -0.5043087365133281 | [157] | [57,19,26] | -5 | hSpCas9 | negative selection | 795320 | 677083 | 677106 | 16 | - | 26627737 | DLD1 | viability | CATGTAGGTGAGGAAGCGCCAGG | RHBDL1 | ENSG00000103269 | 0.6290220034266139 | [128] | [47,72,65] | 6 | hSpCas9 | negative selection | 795321 | 677360 | 677383 | 16 | - | 26627737 | DLD1 | viability | GCACGCCTGCCAGGTAGAGCAGG | RHBDL1 | ENSG00000103269 | 0.4883137924789578 | [288] | [179,95,105] | 5 | hSpCas9 | negative selection | 795322 | 677541 | 677564 | 16 | - | 26627737 | DLD1 | viability | TTACCATGACAACGTTGGCCAGG | RHBDL1 | ENSG00000103269 | -0.05388631720541098 | [420] | [141,240,18] | 0 | hSpCas9 | negative selection | 795323 | 675777 | 675800 | 16 | + | 26627737 | GBM cells | viability after 5 days | CCCGGCCAGGCTCTATGGACAGG | RHBDL1 | ENSG00000103269 | 0.15950510479115076 | [393] | [190,280] | 2 | hSpCas9 | negative selection | 877633 | 676443 | 676466 | 16 | + | 26627737 | GBM cells | viability after 5 days | CCTGGCTCAGAGCAACGAGCAGG | RHBDL1 | ENSG00000103269 | 0.8124991230682124 | [85] | [71,89] | 9 | hSpCas9 | negative selection | 877634 | 676824 | 676847 | 16 | - | 26627737 | GBM cells | viability after 5 days | GACGGTAGAAGTACCAGCGGCGG | RHBDL1 | ENSG00000103269 | -0.19320432710274593 | [96] | [47,42] | -3 | hSpCas9 | negative selection | 877635 | 677083 | 677106 | 16 | - | 26627737 | GBM cells | viability after 5 days | CATGTAGGTGAGGAAGCGCCAGG | RHBDL1 | ENSG00000103269 | -0.8229842711915787 | [126] | [30,45] | -8 | hSpCas9 | negative selection | 877636 | 677360 | 677383 | 16 | - | 26627737 | GBM cells | viability after 5 days | GCACGCCTGCCAGGTAGAGCAGG | RHBDL1 | ENSG00000103269 | 0.6829097815117855 | [168] | [140,149] | 8 | hSpCas9 | negative selection | 877637 | 677541 | 677564 | 16 | - | 26627737 | GBM cells | viability after 5 days | TTACCATGACAACGTTGGCCAGG | RHBDL1 | ENSG00000103269 | 0.6790370514680208 | [190] | [186,140] | 8 | hSpCas9 | negative selection | 877638 | 675777 | 675800 | 16 | + | 26627737 | GBM cells | viability after 13 days | CCCGGCCAGGCTCTATGGACAGG | RHBDL1 | ENSG00000103269 | 0.4671733162371664 | [393] | [305,286] | 6 | hSpCas9 | negative selection | 959948 | 676443 | 676466 | 16 | + | 26627737 | GBM cells | viability after 13 days | CCTGGCTCAGAGCAACGAGCAGG | RHBDL1 | ENSG00000103269 | 0.30354057722970507 | [85] | [61,53] | 4 | hSpCas9 | negative selection | 959949 | 676824 | 676847 | 16 | - | 26627737 | GBM cells | viability after 13 days | GACGGTAGAAGTACCAGCGGCGG | RHBDL1 | ENSG00000103269 | 0.4544707038317618 | [96] | [102,46] | 6 | hSpCas9 | negative selection | 959950 | 677083 | 677106 | 16 | - | 26627737 | GBM cells | viability after 13 days | CATGTAGGTGAGGAAGCGCCAGG | RHBDL1 | ENSG00000103269 | -0.7152747849682941 | [126] | [52,32] | -7 | hSpCas9 | negative selection | 959951 | 677360 | 677383 | 16 | - | 26627737 | GBM cells | viability after 13 days | GCACGCCTGCCAGGTAGAGCAGG | RHBDL1 | ENSG00000103269 | 0.9901253366471441 | [168] | [185,178] | 9 | hSpCas9 | negative selection | 959952 | 677541 | 677564 | 16 | - | 26627737 | GBM cells | viability after 13 days | TTACCATGACAACGTTGGCCAGG | RHBDL1 | ENSG00000103269 | 0.6494270933343558 | [190] | [161,162] | 7 | hSpCas9 | negative selection | 959953 | 675777 | 675800 | 16 | + | 26627737 | GBM cells | viability after 21 days | CCCGGCCAGGCTCTATGGACAGG | RHBDL1 | ENSG00000103269 | 0.32719854575493723 | [393] | [290,247] | 3 | hSpCas9 | negative selection | 1042263 | 676443 | 676466 | 16 | + | 26627737 | GBM cells | viability after 21 days | CCTGGCTCAGAGCAACGAGCAGG | RHBDL1 | ENSG00000103269 | 0.4753495623899384 | [85] | [65,63] | 5 | hSpCas9 | negative selection | 1042264 | 676824 | 676847 | 16 | - | 26627737 | GBM cells | viability after 21 days | GACGGTAGAAGTACCAGCGGCGG | RHBDL1 | ENSG00000103269 | 0.9801435074512836 | [96] | [104,102] | 8 | hSpCas9 | negative selection | 1042265 | 677083 | 677106 | 16 | - | 26627737 | GBM cells | viability after 21 days | CATGTAGGTGAGGAAGCGCCAGG | RHBDL1 | ENSG00000103269 | -0.14523417619821855 | [126] | [64,59] | -1 | hSpCas9 | negative selection | 1042266 | 677360 | 677383 | 16 | - | 26627737 | GBM cells | viability after 21 days | GCACGCCTGCCAGGTAGAGCAGG | RHBDL1 | ENSG00000103269 | 0.6422486627082574 | [168] | [147,138] | 6 | hSpCas9 | negative selection | 1042267 | 677541 | 677564 | 16 | - | 26627737 | GBM cells | viability after 21 days | TTACCATGACAACGTTGGCCAGG | RHBDL1 | ENSG00000103269 | 0.11458944478993854 | [190] | [115,108] | 1 | hSpCas9 | negative selection | 1042268 | 675777 | 675800 | 16 | + | 26627737 | RPE1 | viability after 9 days | CCCGGCCAGGCTCTATGGACAGG | RHBDL1 | ENSG00000103269 | -0.7235564756098289 | [1510] | [337,219] | -5 | hSpCas9 | negative selection | 1124578 | 676443 | 676466 | 16 | + | 26627737 | RPE1 | viability after 9 days | CCTGGCTCAGAGCAACGAGCAGG | RHBDL1 | ENSG00000103269 | -2.2746884557447915 | [651] | [39,44] | -9 | hSpCas9 | negative selection | 1124579 | 676824 | 676847 | 16 | - | 26627737 | RPE1 | viability after 9 days | GACGGTAGAAGTACCAGCGGCGG | RHBDL1 | ENSG00000103269 | -3.6052903238872633 | [673] | [29,0] | -9 | hSpCas9 | negative selection | 1124580 | 677083 | 677106 | 16 | - | 26627737 | RPE1 | viability after 9 days | CATGTAGGTGAGGAAGCGCCAGG | RHBDL1 | ENSG00000103269 | -0.09842483980283556 | [373] | [135,74] | 0 | hSpCas9 | negative selection | 1124581 | 677360 | 677383 | 16 | - | 26627737 | RPE1 | viability after 9 days | GCACGCCTGCCAGGTAGAGCAGG | RHBDL1 | ENSG00000103269 | 6.950915314109523 | [3] | [119,199] | 9 | hSpCas9 | negative selection | 1124582 | 677541 | 677564 | 16 | - | 26627737 | RPE1 | viability after 9 days | TTACCATGACAACGTTGGCCAGG | RHBDL1 | ENSG00000103269 | -0.017267875647900555 | [1066] | [333,324] | 0 | hSpCas9 | negative selection | 1124583 | 675777 | 675800 | 16 | + | 26627737 | RPE1 | viability after 12 days | CCCGGCCAGGCTCTATGGACAGG | RHBDL1 | ENSG00000103269 | -0.6134626308569359 | [1510] | [361,162] | -4 | hSpCas9 | negative selection | 1206893 | 676443 | 676466 | 16 | + | 26627737 | RPE1 | viability after 12 days | CCTGGCTCAGAGCAACGAGCAGG | RHBDL1 | ENSG00000103269 | -2.034041253444489 | [651] | [51,32] | -8 | hSpCas9 | negative selection | 1206894 | 676824 | 676847 | 16 | - | 26627737 | RPE1 | viability after 12 days | GACGGTAGAAGTACCAGCGGCGG | RHBDL1 | ENSG00000103269 | -3.252565856065135 | [673] | [35,0] | -9 | hSpCas9 | negative selection | 1206895 | 677083 | 677106 | 16 | - | 26627737 | RPE1 | viability after 12 days | CATGTAGGTGAGGAAGCGCCAGG | RHBDL1 | ENSG00000103269 | -0.1452550149877474 | [373] | [153,23] | -1 | hSpCas9 | negative selection | 1206896 | 677360 | 677383 | 16 | - | 26627737 | RPE1 | viability after 12 days | GCACGCCTGCCAGGTAGAGCAGG | RHBDL1 | ENSG00000103269 | 7.405716776980433 | [3] | [121,245] | 9 | hSpCas9 | negative selection | 1206897 | 677541 | 677564 | 16 | - | 26627737 | RPE1 | viability after 12 days | TTACCATGACAACGTTGGCCAGG | RHBDL1 | ENSG00000103269 | 0.31539213471932104 | [1066] | [431,276] | 2 | hSpCas9 | negative selection | 1206898 | 675777 | 675800 | 16 | + | 26627737 | RPE1 | viability after 15 days | CCCGGCCAGGCTCTATGGACAGG | RHBDL1 | ENSG00000103269 | -0.541488543574197 | [1510] | [255,329] | -3 | hSpCas9 | negative selection | 1289208 | 676443 | 676466 | 16 | + | 26627737 | RPE1 | viability after 15 days | CCTGGCTCAGAGCAACGAGCAGG | RHBDL1 | ENSG00000103269 | -1.2262178053332886 | [651] | [59,96] | -6 | hSpCas9 | negative selection | 1289209 | 676824 | 676847 | 16 | - | 26627737 | RPE1 | viability after 15 days | GACGGTAGAAGTACCAGCGGCGG | RHBDL1 | ENSG00000103269 | -2.1743241595878313 | [673] | [84,0] | -8 | hSpCas9 | negative selection | 1289210 | 677083 | 677106 | 16 | - | 26627737 | RPE1 | viability after 15 days | CATGTAGGTGAGGAAGCGCCAGG | RHBDL1 | ENSG00000103269 | -0.14253100627560755 | [373] | [188,5] | -1 | hSpCas9 | negative selection | 1289211 | 677360 | 677383 | 16 | - | 26627737 | RPE1 | viability after 15 days | GCACGCCTGCCAGGTAGAGCAGG | RHBDL1 | ENSG00000103269 | 6.591339932304291 | [3] | [74,141] | 9 | hSpCas9 | negative selection | 1289212 | 677541 | 677564 | 16 | - | 26627737 | RPE1 | viability after 15 days | TTACCATGACAACGTTGGCCAGG | RHBDL1 | ENSG00000103269 | 0.3361886655646714 | [1066] | [603,165] | 2 | hSpCas9 | negative selection | 1289213 | 675777 | 675800 | 16 | + | 26627737 | RPE1 | viability after 18 days | CCCGGCCAGGCTCTATGGACAGG | RHBDL1 | ENSG00000103269 | -1.2785698677992245 | [1510] | [155,180] | -7 | hSpCas9 | negative selection | 1371523 | 676443 | 676466 | 16 | + | 26627737 | RPE1 | viability after 18 days | CCTGGCTCAGAGCAACGAGCAGG | RHBDL1 | ENSG00000103269 | -1.2233292050944766 | [651] | [12,141] | -6 | hSpCas9 | negative selection | 1371524 | 676824 | 676847 | 16 | - | 26627737 | RPE1 | viability after 18 days | GACGGTAGAAGTACCAGCGGCGG | RHBDL1 | ENSG00000103269 | -4.559150725522054 | [673] | [13,0] | -9 | hSpCas9 | negative selection | 1371525 | 677083 | 677106 | 16 | - | 26627737 | RPE1 | viability after 18 days | CATGTAGGTGAGGAAGCGCCAGG | RHBDL1 | ENSG00000103269 | -0.34421424239748655 | [373] | [137,16] | -2 | hSpCas9 | negative selection | 1371526 | 677360 | 677383 | 16 | - | 26627737 | RPE1 | viability after 18 days | GCACGCCTGCCAGGTAGAGCAGG | RHBDL1 | ENSG00000103269 | 7.126351297960454 | [3] | [130,171] | 9 | hSpCas9 | negative selection | 1371527 | 677541 | 677564 | 16 | - | 26627737 | RPE1 | viability after 18 days | TTACCATGACAACGTTGGCCAGG | RHBDL1 | ENSG00000103269 | -0.47794094931159425 | [1066] | [315,89] | -3 | hSpCas9 | negative selection | 1371528 | 675777 | 675800 | 16 | + | 26627737 | HeLa | viability after 8 days | CCCGGCCAGGCTCTATGGACAGG | RHBDL1 | ENSG00000103269 | -0.6418666420976173 | [944] | [358,268,188] | -6 | hSpCas9 | negative selection | 1453838 | 676443 | 676466 | 16 | + | 26627737 | HeLa | viability after 8 days | CCTGGCTCAGAGCAACGAGCAGG | RHBDL1 | ENSG00000103269 | 0.34337303033608224 | [126] | [101,39,74] | 3 | hSpCas9 | negative selection | 1453839 | 676824 | 676847 | 16 | - | 26627737 | HeLa | viability after 8 days | GACGGTAGAAGTACCAGCGGCGG | RHBDL1 | ENSG00000103269 | 0.22207242925387333 | [313] | [62,161,226] | 2 | hSpCas9 | negative selection | 1453840 | 677083 | 677106 | 16 | - | 26627737 | HeLa | viability after 8 days | CATGTAGGTGAGGAAGCGCCAGG | RHBDL1 | ENSG00000103269 | 1.7894422639744485 | [70] | [197,13,126] | 9 | hSpCas9 | negative selection | 1453841 | 677360 | 677383 | 16 | - | 26627737 | HeLa | viability after 8 days | GCACGCCTGCCAGGTAGAGCAGG | RHBDL1 | ENSG00000103269 | -0.24522528388973142 | [591] | [157,308,174] | -2 | hSpCas9 | negative selection | 1453842 | 677541 | 677564 | 16 | - | 26627737 | HeLa | viability after 8 days | TTACCATGACAACGTTGGCCAGG | RHBDL1 | ENSG00000103269 | 1.0963330881170648 | [283] | [302,230,266] | 8 | hSpCas9 | negative selection | 1453843 | 675777 | 675800 | 16 | + | 26627737 | HeLa | viability after 12 days | CCCGGCCAGGCTCTATGGACAGG | RHBDL1 | ENSG00000103269 | -0.259026125252086 | [944] | [408,207,376] | -2 | hSpCas9 | negative selection | 1536153 | 676443 | 676466 | 16 | + | 26627737 | HeLa | viability after 12 days | CCTGGCTCAGAGCAACGAGCAGG | RHBDL1 | ENSG00000103269 | -0.4889635945688886 | [126] | [55,15,42] | -4 | hSpCas9 | negative selection | 1536154 | 676824 | 676847 | 16 | - | 26627737 | HeLa | viability after 12 days | GACGGTAGAAGTACCAGCGGCGG | RHBDL1 | ENSG00000103269 | 0.2907811576733284 | [313] | [265,10,217] | 2 | hSpCas9 | negative selection | 1536155 | 677083 | 677106 | 16 | - | 26627737 | HeLa | viability after 12 days | CATGTAGGTGAGGAAGCGCCAGG | RHBDL1 | ENSG00000103269 | 1.530784759204099 | [70] | [101,54,100] | 8 | hSpCas9 | negative selection | 1536156 | 677360 | 677383 | 16 | - | 26627737 | HeLa | viability after 12 days | GCACGCCTGCCAGGTAGAGCAGG | RHBDL1 | ENSG00000103269 | -0.7070715520897316 | [591] | [22,148,273] | -6 | hSpCas9 | negative selection | 1536157 | 677541 | 677564 | 16 | - | 26627737 | HeLa | viability after 12 days | TTACCATGACAACGTTGGCCAGG | RHBDL1 | ENSG00000103269 | 1.249546827153704 | [283] | [303,230,307] | 8 | hSpCas9 | negative selection | 1536158 | 675777 | 675800 | 16 | + | 26627737 | HeLa | viability after 15 days | CCCGGCCAGGCTCTATGGACAGG | RHBDL1 | ENSG00000103269 | -0.8709518380684371 | [944] | [108,232,296] | -6 | hSpCas9 | negative selection | 1618468 | 676443 | 676466 | 16 | + | 26627737 | HeLa | viability after 15 days | CCTGGCTCAGAGCAACGAGCAGG | RHBDL1 | ENSG00000103269 | 0.7061134704214578 | [126] | [48,101,103] | 5 | hSpCas9 | negative selection | 1618469 | 676824 | 676847 | 16 | - | 26627737 | HeLa | viability after 15 days | GACGGTAGAAGTACCAGCGGCGG | RHBDL1 | ENSG00000103269 | -0.05011186248549648 | [313] | [80,32,267] | 0 | hSpCas9 | negative selection | 1618470 | 677083 | 677106 | 16 | - | 26627737 | HeLa | viability after 15 days | CATGTAGGTGAGGAAGCGCCAGG | RHBDL1 | ENSG00000103269 | 1.9519809163738142 | [70] | [87,36,218] | 9 | hSpCas9 | negative selection | 1618471 | 677360 | 677383 | 16 | - | 26627737 | HeLa | viability after 15 days | GCACGCCTGCCAGGTAGAGCAGG | RHBDL1 | ENSG00000103269 | -0.7641654940615005 | [591] | [8,184,240] | -6 | hSpCas9 | negative selection | 1618472 | 677541 | 677564 | 16 | - | 26627737 | HeLa | viability after 15 days | TTACCATGACAACGTTGGCCAGG | RHBDL1 | ENSG00000103269 | 1.3043469599392645 | [283] | [169,403,283] | 8 | hSpCas9 | negative selection | 1618473 | 675777 | 675800 | 16 | + | 26627737 | HeLa | viability after 18 days | CCCGGCCAGGCTCTATGGACAGG | RHBDL1 | ENSG00000103269 | -0.8453686089022907 | [944] | [73,200,296] | -6 | hSpCas9 | negative selection | 1700783 | 676443 | 676466 | 16 | + | 26627737 | HeLa | viability after 18 days | CCTGGCTCAGAGCAACGAGCAGG | RHBDL1 | ENSG00000103269 | 0.7004368185480127 | [126] | [34,80,103] | 5 | hSpCas9 | negative selection | 1700784 | 676824 | 676847 | 16 | - | 26627737 | HeLa | viability after 18 days | GACGGTAGAAGTACCAGCGGCGG | RHBDL1 | ENSG00000103269 | -0.05256644486568124 | [313] | [50,30,267] | 0 | hSpCas9 | negative selection | 1700785 | 677083 | 677106 | 16 | - | 26627737 | HeLa | viability after 18 days | CATGTAGGTGAGGAAGCGCCAGG | RHBDL1 | ENSG00000103269 | 1.9335946212404258 | [70] | [55,30,218] | 9 | hSpCas9 | negative selection | 1700786 | 677360 | 677383 | 16 | - | 26627737 | HeLa | viability after 18 days | GCACGCCTGCCAGGTAGAGCAGG | RHBDL1 | ENSG00000103269 | -0.7310271910883912 | [591] | [6,159,240] | -6 | hSpCas9 | negative selection | 1700787 | 677541 | 677564 | 16 | - | 26627737 | HeLa | viability after 18 days | TTACCATGACAACGTTGGCCAGG | RHBDL1 | ENSG00000103269 | 1.2926569625381714 | [283] | [109,333,283] | 8 | hSpCas9 | negative selection | 1700788 | 675777 | 675800 | 16 | + | 26627737 | HCT116 | viability after 6 days | CCCGGCCAGGCTCTATGGACAGG | RHBDL1 | ENSG00000103269 | -0.2905242215382662 | [2023] | [419,171] | -2 | hSpCas9 | negative selection | 1783098 | 676443 | 676466 | 16 | + | 26627737 | HCT116 | viability after 6 days | CCTGGCTCAGAGCAACGAGCAGG | RHBDL1 | ENSG00000103269 | 1.5062163647784552 | [198] | [84,90] | 7 | hSpCas9 | negative selection | 1783099 | 676824 | 676847 | 16 | - | 26627737 | HCT116 | viability after 6 days | GACGGTAGAAGTACCAGCGGCGG | RHBDL1 | ENSG00000103269 | 0.26992595333975306 | [441] | [193,22] | 1 | hSpCas9 | negative selection | 1783100 | 677083 | 677106 | 16 | - | 26627737 | HCT116 | viability after 6 days | CATGTAGGTGAGGAAGCGCCAGG | RHBDL1 | ENSG00000103269 | -1.261292297148568 | [517] | [71,12] | -6 | hSpCas9 | negative selection | 1783101 | 677360 | 677383 | 16 | - | 26627737 | HCT116 | viability after 6 days | GCACGCCTGCCAGGTAGAGCAGG | RHBDL1 | ENSG00000103269 | 1.0214749768196605 | [439] | [307,47] | 5 | hSpCas9 | negative selection | 1783102 | 677541 | 677564 | 16 | - | 26627737 | HCT116 | viability after 6 days | TTACCATGACAACGTTGGCCAGG | RHBDL1 | ENSG00000103269 | 0.7405815223127535 | [540] | [47,193] | 4 | hSpCas9 | negative selection | 1783103 | 675777 | 675800 | 16 | + | 26627737 | HCT116 | viability after 8 days | CCCGGCCAGGCTCTATGGACAGG | RHBDL1 | ENSG00000103269 | 0.1366198718370013 | [614] | [394,430,292] | 1 | hSpCas9 | negative selection | 1865413 | 676443 | 676466 | 16 | + | 26627737 | HCT116 | viability after 8 days | CCTGGCTCAGAGCAACGAGCAGG | RHBDL1 | ENSG00000103269 | -0.3484675300442671 | [192] | [77,48,122] | -4 | hSpCas9 | negative selection | 1865414 | 676824 | 676847 | 16 | - | 26627737 | HCT116 | viability after 8 days | GACGGTAGAAGTACCAGCGGCGG | RHBDL1 | ENSG00000103269 | 0.235316957909251 | [177] | [106,104,133] | 2 | hSpCas9 | negative selection | 1865415 | 677083 | 677106 | 16 | - | 26627737 | HCT116 | viability after 8 days | CATGTAGGTGAGGAAGCGCCAGG | RHBDL1 | ENSG00000103269 | 0.16602281305594946 | [169] | [97,97,118] | 2 | hSpCas9 | negative selection | 1865416 | 677360 | 677383 | 16 | - | 26627737 | HCT116 | viability after 8 days | GCACGCCTGCCAGGTAGAGCAGG | RHBDL1 | ENSG00000103269 | -0.865173511521693 | [520] | [153,181,136] | -8 | hSpCas9 | negative selection | 1865417 | 677541 | 677564 | 16 | - | 26627737 | HCT116 | viability after 8 days | TTACCATGACAACGTTGGCCAGG | RHBDL1 | ENSG00000103269 | 1.7800719576993922 | [81] | [163,170,130] | 9 | hSpCas9 | negative selection | 1865418 | 675777 | 675800 | 16 | + | 26627737 | HCT116 | viability after 9 days | CCCGGCCAGGCTCTATGGACAGG | RHBDL1 | ENSG00000103269 | -0.685725023380142 | [2023] | [502,203] | -5 | hSpCas9 | negative selection | 1947728 | 676443 | 676466 | 16 | + | 26627737 | HCT116 | viability after 9 days | CCTGGCTCAGAGCAACGAGCAGG | RHBDL1 | ENSG00000103269 | 1.3598363161571705 | [198] | [189,93] | 8 | hSpCas9 | negative selection | 1947729 | 676824 | 676847 | 16 | - | 26627737 | HCT116 | viability after 9 days | GACGGTAGAAGTACCAGCGGCGG | RHBDL1 | ENSG00000103269 | -0.476430009349625 | [441] | [33,124] | -3 | hSpCas9 | negative selection | 1947730 | 677083 | 677106 | 16 | - | 26627737 | HCT116 | viability after 9 days | CATGTAGGTGAGGAAGCGCCAGG | RHBDL1 | ENSG00000103269 | 0.5138574619191241 | [517] | [311,106] | 4 | hSpCas9 | negative selection | 1947731 | 677360 | 677383 | 16 | - | 26627737 | HCT116 | viability after 9 days | GCACGCCTGCCAGGTAGAGCAGG | RHBDL1 | ENSG00000103269 | 0.32489306580412847 | [439] | [178,121] | 2 | hSpCas9 | negative selection | 1947732 | 677541 | 677564 | 16 | - | 26627737 | HCT116 | viability after 9 days | TTACCATGACAACGTTGGCCAGG | RHBDL1 | ENSG00000103269 | 1.2424451660716993 | [540] | [629,113] | 7 | hSpCas9 | negative selection | 1947733 | 675777 | 675800 | 16 | + | 26627737 | HCT116 | viability after 12 days | CCCGGCCAGGCTCTATGGACAGG | RHBDL1 | ENSG00000103269 | -0.2710160374726247 | [614] | [223,292,290] | -3 | hSpCas9 | negative selection | 2030043 | 676443 | 676466 | 16 | + | 26627737 | HCT116 | viability after 12 days | CCTGGCTCAGAGCAACGAGCAGG | RHBDL1 | ENSG00000103269 | -0.22720804086301305 | [192] | [124,62,67] | -2 | hSpCas9 | negative selection | 2030044 | 676824 | 676847 | 16 | - | 26627737 | HCT116 | viability after 12 days | GACGGTAGAAGTACCAGCGGCGG | RHBDL1 | ENSG00000103269 | 0.16656312644566318 | [177] | [59,107,150] | 1 | hSpCas9 | negative selection | 2030045 | 677083 | 677106 | 16 | - | 26627737 | HCT116 | viability after 12 days | CATGTAGGTGAGGAAGCGCCAGG | RHBDL1 | ENSG00000103269 | -0.011843660265562939 | [169] | [32,182,56] | 0 | hSpCas9 | negative selection | 2030046 | 677360 | 677383 | 16 | - | 26627737 | HCT116 | viability after 12 days | GCACGCCTGCCAGGTAGAGCAGG | RHBDL1 | ENSG00000103269 | -0.5885701779600994 | [520] | [272,171,92] | -6 | hSpCas9 | negative selection | 2030047 | 677541 | 677564 | 16 | - | 26627737 | HCT116 | viability after 12 days | TTACCATGACAACGTTGGCCAGG | RHBDL1 | ENSG00000103269 | 1.9241319259980547 | [81] | [227,164,91] | 9 | hSpCas9 | negative selection | 2030048 | 675777 | 675800 | 16 | + | 26627737 | HCT116 | viability after 15 days | CCCGGCCAGGCTCTATGGACAGG | RHBDL1 | ENSG00000103269 | 0.12867379639151988 | [614] | [439,423,301] | 1 | hSpCas9 | negative selection | 2112358 | 676443 | 676466 | 16 | + | 26627737 | HCT116 | viability after 15 days | CCTGGCTCAGAGCAACGAGCAGG | RHBDL1 | ENSG00000103269 | -0.025180713702939506 | [192] | [122,56,147] | 0 | hSpCas9 | negative selection | 2112359 | 676824 | 676847 | 16 | - | 26627737 | HCT116 | viability after 15 days | GACGGTAGAAGTACCAGCGGCGG | RHBDL1 | ENSG00000103269 | -0.19339504442774003 | [177] | [78,103,83] | -2 | hSpCas9 | negative selection | 2112360 | 677083 | 677106 | 16 | - | 26627737 | HCT116 | viability after 15 days | CATGTAGGTGAGGAAGCGCCAGG | RHBDL1 | ENSG00000103269 | 0.016172036658774314 | [169] | [11,121,150] | 0 | hSpCas9 | negative selection | 2112361 | 677360 | 677383 | 16 | - | 26627737 | HCT116 | viability after 15 days | GCACGCCTGCCAGGTAGAGCAGG | RHBDL1 | ENSG00000103269 | -0.45717743727304494 | [520] | [271,301,87] | -5 | hSpCas9 | negative selection | 2112362 | 677541 | 677564 | 16 | - | 26627737 | HCT116 | viability after 15 days | TTACCATGACAACGTTGGCCAGG | RHBDL1 | ENSG00000103269 | 1.9172730181689812 | [81] | [198,226,110] | 9 | hSpCas9 | negative selection | 2112363 | 675777 | 675800 | 16 | + | 26627737 | HCT116 | viability after 18 days | CCCGGCCAGGCTCTATGGACAGG | RHBDL1 | ENSG00000103269 | -0.23056349280848698 | [614] | [165,256,340] | -2 | hSpCas9 | negative selection | 2194673 | 676443 | 676466 | 16 | + | 26627737 | HCT116 | viability after 18 days | CCTGGCTCAGAGCAACGAGCAGG | RHBDL1 | ENSG00000103269 | 0.14724459753888008 | [192] | [155,55,100] | 1 | hSpCas9 | negative selection | 2194674 | 676824 | 676847 | 16 | - | 26627737 | HCT116 | viability after 18 days | GACGGTAGAAGTACCAGCGGCGG | RHBDL1 | ENSG00000103269 | 0.2860541404218315 | [177] | [11,183,113] | 2 | hSpCas9 | negative selection | 2194675 | 677083 | 677106 | 16 | - | 26627737 | HCT116 | viability after 18 days | CATGTAGGTGAGGAAGCGCCAGG | RHBDL1 | ENSG00000103269 | -0.14140039684898265 | [169] | [85,82,52] | -1 | hSpCas9 | negative selection | 2194676 | 677360 | 677383 | 16 | - | 26627737 | HCT116 | viability after 18 days | GCACGCCTGCCAGGTAGAGCAGG | RHBDL1 | ENSG00000103269 | -0.7040564732557844 | [520] | [268,131,59] | -6 | hSpCas9 | negative selection | 2194677 | 677541 | 677564 | 16 | - | 26627737 | HCT116 | viability after 18 days | TTACCATGACAACGTTGGCCAGG | RHBDL1 | ENSG00000103269 | 1.4249093010323866 | [81] | [195,80,40] | 8 | hSpCas9 | negative selection | 2194678 | 676744 | 676767 | 16 | - | 27453484 | HT29 | resistance to T3SS1-dependent cytotoxicity | CCTAGGCCTGGCTCATCCAGCGG | RHBDL1 | ENSG00000103269 | -0.36005001646024387 | [3,3] | [3,1] | -5 | hSpCas9 | positive selection | 3016728 | 676862 | 676885 | 16 | - | 27453484 | HT29 | resistance to T3SS1-dependent cytotoxicity | GACCGAGGCCATGAACACGGGGG | RHBDL1 | ENSG00000103269 | -0.366194496946469 | [2,2] | [1,0] | -5 | hSpCas9 | positive selection | 3016729 | 676827 | 676850 | 16 | - | 27453484 | HT29 | resistance to T3SS1-dependent cytotoxicity | GGTGACGGTAGAAGTACCAGCGG | RHBDL1 | ENSG00000103269 | -0.006467613740958916 | [3,3] | [4,0] | 0 | hSpCas9 | positive selection | 3016730 | 676732 | 676755 | 16 | - | 27453484 | HT29 | resistance to T3SS1-dependent cytotoxicity | TCATCCAGCGGCCCGTCCCGGGG | RHBDL1 | ENSG00000103269 | 0.4998812402994066 | [2,2] | [2,3] | 8 | hSpCas9 | positive selection | 3016731 | 676744 | 676767 | 16 | - | 27453484 | HT29 | resistance to T3SS2-dependent cytotoxicity | CCTAGGCCTGGCTCATCCAGCGG | RHBDL1 | ENSG00000103269 | 0.6896642041740504 | [3,3] | [4,4] | 9 | hSpCas9 | positive selection | 3084586 | 676862 | 676885 | 16 | - | 27453484 | HT29 | resistance to T3SS2-dependent cytotoxicity | GACCGAGGCCATGAACACGGGGG | RHBDL1 | ENSG00000103269 | -0.4838045026492938 | [2,2] | [0,0] | -7 | hSpCas9 | positive selection | 3084587 | 676827 | 676850 | 16 | - | 27453484 | HT29 | resistance to T3SS2-dependent cytotoxicity | GGTGACGGTAGAAGTACCAGCGG | RHBDL1 | ENSG00000103269 | 0.40760292751817967 | [3,3] | [2,3] | 7 | hSpCas9 | positive selection | 3084588 | 676732 | 676755 | 16 | - | 27453484 | HT29 | resistance to T3SS2-dependent cytotoxicity | TCATCCAGCGGCCCGTCCCGGGG | RHBDL1 | ENSG00000103269 | 0.7176008595551476 | [2,2] | [1,3] | 9 | hSpCas9 | positive selection | 3084589 | 676773 | 676796 | | + | 24336571 | A375 | resistance to PLX after 7 days | CAAGCGGTTTGTGCGTTACGTGG | RHBDL1 | ENSG00000103269 | -0.1968764495626485 | [6,8] | [5,7] | -6 | hSpCas9 | positive selection | 3140834 | 677303 | 677326 | | - | 24336571 | A375 | resistance to PLX after 7 days | GCACCCCGATCATCAGCTGCAGG | RHBDL1 | ENSG00000103269 | -0.14552010341232877 | [15,15] | [13,13] | -5 | hSpCas9 | positive selection | 3140835 | 676706 | 676729 | | - | 24336571 | A375 | resistance to PLX after 7 days | TGCCCGCTGTCCGTTAGCAATGG | RHBDL1 | ENSG00000103269 | -0.4904493135649149 | [18,17] | [13,11] | -9 | hSpCas9 | positive selection | 3140836 | 676773 | 676796 | | + | 24336571 | A375 | resistance to PLX after 14 days | CAAGCGGTTTGTGCGTTACGTGG | RHBDL1 | ENSG00000103269 | -0.31945132070090576 | [8,6] | [1,2] | -4 | hSpCas9 | positive selection | 3198627 | 677303 | 677326 | | - | 24336571 | A375 | resistance to PLX after 14 days | GCACCCCGATCATCAGCTGCAGG | RHBDL1 | ENSG00000103269 | -0.29079569297573293 | [13,12] | [3,5] | -3 | hSpCas9 | positive selection | 3198628 | 676706 | 676729 | | - | 24336571 | A375 | resistance to PLX after 14 days | TGCCCGCTGTCCGTTAGCAATGG | RHBDL1 | ENSG00000103269 | 0.1308210457199988 | [9,13] | [4,6] | 1 | hSpCas9 | positive selection | 3198629 | 676773 | 676796 | | + | 24336571 | A375 | viability after 7 days | CAAGCGGTTTGTGCGTTACGTGG | RHBDL1 | ENSG00000103269 | 0.8332324586410601 | [4] | [6,8] | 9 | hSpCas9 | negative selection | 3256420 | 677303 | 677326 | | - | 24336571 | A375 | viability after 7 days | GCACCCCGATCATCAGCTGCAGG | RHBDL1 | ENSG00000103269 | -0.2902485750205943 | [20] | [15,15] | -4 | hSpCas9 | negative selection | 3256421 | 676706 | 676729 | | - | 24336571 | A375 | viability after 7 days | TGCCCGCTGTCCGTTAGCAATGG | RHBDL1 | ENSG00000103269 | -0.050346579624153565 | [19] | [18,17] | 0 | hSpCas9 | negative selection | 3256422 | 676773 | 676796 | | + | 24336571 | A375 | viability after 14 days | CAAGCGGTTTGTGCGTTACGTGG | RHBDL1 | ENSG00000103269 | 0.8147535913526629 | [4] | [8,6] | 8 | hSpCas9 | negative selection | 3314213 | 677303 | 677326 | | - | 24336571 | A375 | viability after 14 days | GCACCCCGATCATCAGCTGCAGG | RHBDL1 | ENSG00000103269 | -0.5045144000805671 | [20] | [13,12] | -6 | hSpCas9 | negative selection | 3314214 | 676706 | 676729 | | - | 24336571 | A375 | viability after 14 days | TGCCCGCTGTCCGTTAGCAATGG | RHBDL1 | ENSG00000103269 | -0.6601900745614544 | [19] | [9,13] | -7 | hSpCas9 | negative selection | 3314215 | 676744 | 676767 | 16 | - | 26780180 | HT29 | viability (Avana library 4 designs) | CCTAGGCCTGGCTCATCCAGCGG | RHBDL1 | ENSG00000103269 | 1.27951704145678 | [] | [] | 5 | hSpCas9 | negative selection | 3455070 | 676862 | 676885 | 16 | - | 26780180 | HT29 | viability (Avana library 4 designs) | GACCGAGGCCATGAACACGGGGG | RHBDL1 | ENSG00000103269 | 0.919619402579249 | [] | [] | 3 | hSpCas9 | negative selection | 3455071 | 676827 | 676850 | 16 | - | 26780180 | HT29 | viability (Avana library 4 designs) | GGTGACGGTAGAAGTACCAGCGG | RHBDL1 | ENSG00000103269 | 0.958730598459985 | [] | [] | 4 | hSpCas9 | negative selection | 3455072 | 676732 | 676755 | 16 | - | 26780180 | HT29 | viability (Avana library 4 designs) | TCATCCAGCGGCCCGTCCCGGGG | RHBDL1 | ENSG00000103269 | 1.86551228024195 | [] | [] | 7 | hSpCas9 | negative selection | 3455073 | 676827 | 676850 | 16 | - | 26780180 | A375 | viability (Avana lentiCRISPRv2) | GGTGACGGTAGAAGTACCAGCGG | RHBDL1 | ENSG00000103269 | 3.71801225304354 | [] | [] | 6 | hSpCas9 | negative selection | 3552873 | 676732 | 676755 | 16 | - | 26780180 | A375 | viability (Avana lentiCRISPRv2) | TCATCCAGCGGCCCGTCCCGGGG | RHBDL1 | ENSG00000103269 | 3.38742694927613 | [] | [] | 5 | hSpCas9 | negative selection | 3552874 | 676744 | 676767 | 16 | - | 26780180 | A375 | viability (Avana lentiCRISPRv2) | CCTAGGCCTGGCTCATCCAGCGG | RHBDL1 | ENSG00000103269 | 2.23373913912753 | [] | [] | 3 | hSpCas9 | negative selection | 3552875 | 676862 | 676885 | 16 | - | 26780180 | A375 | viability (Avana lentiCRISPRv2) | GACCGAGGCCATGAACACGGGGG | RHBDL1 | ENSG00000103269 | -1.1703728227379 | [] | [] | -1 | hSpCas9 | negative selection | 3552876 | 676824 | 676847 | 16 | - | 26780180 | A375 | viability (Avana lentiCRISPRv2) | GACGGTAGAAGTACCAGCGGCGG | RHBDL1 | ENSG00000103269 | 0.313587462711403 | [] | [] | 0 | hSpCas9 | negative selection | 3552877 | 676973 | 676996 | 16 | + | 26780180 | A375 | viability (Avana lentiCRISPRv2) | CATCGTGTTCCTGTGTTACGGGG | RHBDL1 | ENSG00000103269 | 5.38548253243507 | [] | [] | 8 | hSpCas9 | negative selection | 3552878 | 676827 | 676850 | 16 | - | 26780180 | A375 | viability (Avana lentiGuide) | GGTGACGGTAGAAGTACCAGCGG | RHBDL1 | ENSG00000103269 | 5.2820423274138 | [] | [] | 5 | hSpCas9 | negative selection | 3661532 | 676732 | 676755 | 16 | - | 26780180 | A375 | viability (Avana lentiGuide) | TCATCCAGCGGCCCGTCCCGGGG | RHBDL1 | ENSG00000103269 | 9.10745658151403 | [] | [] | 6 | hSpCas9 | negative selection | 3661533 | 676744 | 676767 | 16 | - | 26780180 | A375 | viability (Avana lentiGuide) | CCTAGGCCTGGCTCATCCAGCGG | RHBDL1 | ENSG00000103269 | 10.5116891942513 | [] | [] | 7 | hSpCas9 | negative selection | 3661534 | 676862 | 676885 | 16 | - | 26780180 | A375 | viability (Avana lentiGuide) | GACCGAGGCCATGAACACGGGGG | RHBDL1 | ENSG00000103269 | 16.0071920015934 | [] | [] | 8 | hSpCas9 | negative selection | 3661535 | 676824 | 676847 | 16 | - | 26780180 | A375 | viability (Avana lentiGuide) | GACGGTAGAAGTACCAGCGGCGG | RHBDL1 | ENSG00000103269 | 6.08948399422384 | [] | [] | 5 | hSpCas9 | negative selection | 3661536 | 676973 | 676996 | 16 | + | 26780180 | A375 | viability (Avana lentiGuide) | CATCGTGTTCCTGTGTTACGGGG | RHBDL1 | ENSG00000103269 | 5.94994545174363 | [] | [] | 5 | hSpCas9 | negative selection | 3661537 | 676827 | 676850 | 16 | - | 26780180 | A375 | resistance to vemurafenib (Avana lentiCRISPRv2) | GGTGACGGTAGAAGTACCAGCGG | RHBDL1 | ENSG00000103269 | 0.020185863842023227 | [4] | [5,3] | 0 | hSpCas9 | positive selection | 3770139 | 676732 | 676755 | 16 | - | 26780180 | A375 | resistance to vemurafenib (Avana lentiCRISPRv2) | TCATCCAGCGGCCCGTCCCGGGG | RHBDL1 | ENSG00000103269 | 0.05325685120365567 | [4] | [4,3] | 1 | hSpCas9 | positive selection | 3770140 | 676744 | 676767 | 16 | - | 26780180 | A375 | resistance to vemurafenib (Avana lentiCRISPRv2) | CCTAGGCCTGGCTCATCCAGCGG | RHBDL1 | ENSG00000103269 | -0.1434707792742468 | [5] | [5,3] | -2 | hSpCas9 | positive selection | 3770141 | 676862 | 676885 | 16 | - | 26780180 | A375 | resistance to vemurafenib (Avana lentiCRISPRv2) | GACCGAGGCCATGAACACGGGGG | RHBDL1 | ENSG00000103269 | -0.9722277950593874 | [4] | [2,0] | -8 | hSpCas9 | positive selection | 3770142 | 676824 | 676847 | 16 | - | 26780180 | A375 | resistance to vemurafenib (Avana lentiCRISPRv2) | GACGGTAGAAGTACCAGCGGCGG | RHBDL1 | ENSG00000103269 | -0.059425371835286595 | [4] | [4,3] | -1 | hSpCas9 | positive selection | 3770143 | 676973 | 676996 | 16 | + | 26780180 | A375 | resistance to vemurafenib (Avana lentiCRISPRv2) | CATCGTGTTCCTGTGTTACGGGG | RHBDL1 | ENSG00000103269 | 0.19057584130262586 | [5] | [6,4] | 5 | hSpCas9 | positive selection | 3770144 | 676827 | 676850 | 16 | - | 26780180 | A375 | resistance to vemurafenib (Avana lentiGuide) | GGTGACGGTAGAAGTACCAGCGG | RHBDL1 | ENSG00000103269 | -0.531728758732443 | [5] | [1,4] | -6 | hSpCas9 | positive selection | 3878746 | 676732 | 676755 | 16 | - | 26780180 | A375 | resistance to vemurafenib (Avana lentiGuide) | TCATCCAGCGGCCCGTCCCGGGG | RHBDL1 | ENSG00000103269 | -1.2933185131910894 | [4] | [0,1] | -9 | hSpCas9 | positive selection | 3878747 | 676744 | 676767 | 16 | - | 26780180 | A375 | resistance to vemurafenib (Avana lentiGuide) | CCTAGGCCTGGCTCATCCAGCGG | RHBDL1 | ENSG00000103269 | -0.13771292364383494 | [5] | [4,3] | -2 | hSpCas9 | positive selection | 3878748 | 676862 | 676885 | 16 | - | 26780180 | A375 | resistance to vemurafenib (Avana lentiGuide) | GACCGAGGCCATGAACACGGGGG | RHBDL1 | ENSG00000103269 | -1.274230036515624 | [4] | [1,0] | -9 | hSpCas9 | positive selection | 3878749 | 676824 | 676847 | 16 | - | 26780180 | A375 | resistance to vemurafenib (Avana lentiGuide) | GACGGTAGAAGTACCAGCGGCGG | RHBDL1 | ENSG00000103269 | 0.12516354780701375 | [5] | [4,4] | 3 | hSpCas9 | positive selection | 3878750 | 676973 | 676996 | 16 | + | 26780180 | A375 | resistance to vemurafenib (Avana lentiGuide) | CATCGTGTTCCTGTGTTACGGGG | RHBDL1 | ENSG00000103269 | 0.0633056408833257 | [5] | [4,4] | 1 | hSpCas9 | positive selection | 3878751 | 676773 | 676796 | 16 | + | 26780180 | A375 | resistance to vemurafenib (GeCKOv1 lentiCRISPRv1) | CAAGCGGTTTGTGCGTTACGTGG | RHBDL1 | ENSG00000103269 | -0.5338276457677955 | [3] | [1,1] | -8 | hSpCas9 | positive selection | 4166310 | 677303 | 677326 | 16 | - | 26780180 | A375 | resistance to vemurafenib (GeCKOv1 lentiCRISPRv1) | GCACCCCGATCATCAGCTGCAGG | RHBDL1 | ENSG00000103269 | -0.11680168864152465 | [3] | [2,2] | -3 | hSpCas9 | positive selection | 4166311 | 676706 | 676729 | 16 | - | 26780180 | A375 | resistance to vemurafenib (GeCKOv1 lentiCRISPRv1) | TGCCCGCTGTCCGTTAGCAATGG | RHBDL1 | ENSG00000103269 | -0.1819744613697726 | [4] | [2,2] | -4 | hSpCas9 | positive selection | 4166312 | 676773 | 676796 | 16 | + | 26780180 | A375 | resistance to vemurafenib (GeCKOv1 lentiGuide) | CAAGCGGTTTGTGCGTTACGTGG | RHBDL1 | ENSG00000103269 | 0.2734420882635086 | [2] | [0,0,4,0] | 2 | hSpCas9 | positive selection | 4230332 | 677303 | 677326 | 16 | - | 26780180 | A375 | resistance to vemurafenib (GeCKOv1 lentiGuide) | GCACCCCGATCATCAGCTGCAGG | RHBDL1 | ENSG00000103269 | 0.852102499478059 | [4] | [1,3,1,4] | 5 | hSpCas9 | positive selection | 4230333 | 676706 | 676729 | 16 | - | 26780180 | A375 | resistance to vemurafenib (GeCKOv1 lentiGuide) | TGCCCGCTGTCCGTTAGCAATGG | RHBDL1 | ENSG00000103269 | 0.19352009432090123 | [3] | [4,0,3,0] | 1 | hSpCas9 | positive selection | 4230334 | 676706 | 676728 | 16 | - | 27760321 | OCIAML3 | viability | GCCCGCTGTCCGTTAGCAATGG | RHBDL1 | ENSG00000103269 | 0.6278115923203381 | [740,653] | [777,923] | 7 | hSpCas9 | negative selection | 4434491 | 676761 | 676783 | 16 | - | 27760321 | OCIAML3 | viability | AAACCGCTTGTAGACACCTAGG | RHBDL1 | ENSG00000103269 | 0.4388021991515362 | [725,594] | [622,792] | 5 | hSpCas9 | negative selection | 4434492 | 676812 | 676834 | 16 | + | 27760321 | OCIAML3 | viability | TTGTGAGGTGGACCGCCGCTGG | RHBDL1 | ENSG00000103269 | 0.09555856292050646 | [630,614] | [483,570] | 1 | hSpCas9 | negative selection | 4434493 | 676862 | 676884 | 16 | - | 27760321 | OCIAML3 | viability | ACCGAGGCCATGAACACGGGGG | RHBDL1 | ENSG00000103269 | 0.0744939678867563 | [564,472] | [459,380] | 0 | hSpCas9 | negative selection | 4434494 | 676991 | 677013 | 16 | + | 27760321 | OCIAML3 | viability | CGGGGCCCGCCTCAACAAGTGG | RHBDL1 | ENSG00000103269 | 0.4153867354313692 | [330,299] | [386,252] | 5 | hSpCas9 | negative selection | 4434495 | 676706 | 676728 | 16 | - | 27760321 | OCIAML2 | viability | GCCCGCTGTCCGTTAGCAATGG | RHBDL1 | ENSG00000103269 | -0.3097043386198358 | [740,653] | [415,504] | -4 | hSpCas9 | negative selection | 4517954 | 676761 | 676783 | 16 | - | 27760321 | OCIAML2 | viability | AAACCGCTTGTAGACACCTAGG | RHBDL1 | ENSG00000103269 | -0.14015793201818677 | [725,594] | [409,577] | -2 | hSpCas9 | negative selection | 4517955 | 676812 | 676834 | 16 | + | 27760321 | OCIAML2 | viability | TTGTGAGGTGGACCGCCGCTGG | RHBDL1 | ENSG00000103269 | 0.12224181181293847 | [630,614] | [478,642] | 1 | hSpCas9 | negative selection | 4517956 | 676862 | 676884 | 16 | - | 27760321 | OCIAML2 | viability | ACCGAGGCCATGAACACGGGGG | RHBDL1 | ENSG00000103269 | -1.050199152374768 | [564,472] | [210,189] | -7 | hSpCas9 | negative selection | 4517957 | 676991 | 677013 | 16 | + | 27760321 | OCIAML2 | viability | CGGGGCCCGCCTCAACAAGTGG | RHBDL1 | ENSG00000103269 | -0.05046551264279575 | [330,299] | [206,297] | 0 | hSpCas9 | negative selection | 4517958 | 676706 | 676728 | 16 | - | 27760321 | MV411 | viability | GCCCGCTGTCCGTTAGCAATGG | RHBDL1 | ENSG00000103269 | 0.8674969944708909 | [740,653] | [643,1129] | 6 | hSpCas9 | negative selection | 4601417 | 676761 | 676783 | 16 | - | 27760321 | MV411 | viability | AAACCGCTTGTAGACACCTAGG | RHBDL1 | ENSG00000103269 | -0.4178090376904796 | [725,594] | [187,529] | -3 | hSpCas9 | negative selection | 4601418 | 676812 | 676834 | 16 | + | 27760321 | MV411 | viability | TTGTGAGGTGGACCGCCGCTGG | RHBDL1 | ENSG00000103269 | 1.0583638870570076 | [630,614] | [1208,330] | 7 | hSpCas9 | negative selection | 4601419 | 676862 | 676884 | 16 | - | 27760321 | MV411 | viability | ACCGAGGCCATGAACACGGGGG | RHBDL1 | ENSG00000103269 | 0.08259410958058108 | [564,472] | [385,323] | 0 | hSpCas9 | negative selection | 4601420 | 676991 | 677013 | 16 | + | 27760321 | MV411 | viability | CGGGGCCCGCCTCAACAAGTGG | RHBDL1 | ENSG00000103269 | 0.6066658878664628 | [330,299] | [309,326] | 4 | hSpCas9 | negative selection | 4601421 | 676706 | 676728 | 16 | - | 27760321 | HL60 | viability | GCCCGCTGTCCGTTAGCAATGG | RHBDL1 | ENSG00000103269 | 0.5513427039676165 | [740,653] | [615,1063] | 6 | hSpCas9 | negative selection | 4684880 | 676761 | 676783 | 16 | - | 27760321 | HL60 | viability | AAACCGCTTGTAGACACCTAGG | RHBDL1 | ENSG00000103269 | 0.6892915634151632 | [725,594] | [659,1083] | 7 | hSpCas9 | negative selection | 4684881 | 676812 | 676834 | 16 | + | 27760321 | HL60 | viability | TTGTGAGGTGGACCGCCGCTGG | RHBDL1 | ENSG00000103269 | 1.3902947936214531 | [630,614] | [1071,1617] | 9 | hSpCas9 | negative selection | 4684882 | 676862 | 676884 | 16 | - | 27760321 | HL60 | viability | ACCGAGGCCATGAACACGGGGG | RHBDL1 | ENSG00000103269 | -0.09116256897254776 | [564,472] | [525,258] | -1 | hSpCas9 | negative selection | 4684883 | 676991 | 677013 | 16 | + | 27760321 | HL60 | viability | CGGGGCCCGCCTCAACAAGTGG | RHBDL1 | ENSG00000103269 | 0.15823351580543343 | [330,299] | [266,308] | 2 | hSpCas9 | negative selection | 4684884 | 676706 | 676728 | 16 | - | 27760321 | HT1080 | viability | GCCCGCTGTCCGTTAGCAATGG | RHBDL1 | ENSG00000103269 | 1.0381295073892955 | [653,510] | [635,301] | 5 | hSpCas9 | negative selection | 4768343 | 676761 | 676783 | 16 | - | 27760321 | HT1080 | viability | AAACCGCTTGTAGACACCTAGG | RHBDL1 | ENSG00000103269 | 0.6305956662871869 | [594,463] | [116,555] | 3 | hSpCas9 | negative selection | 4768344 | 676812 | 676834 | 16 | + | 27760321 | HT1080 | viability | TTGTGAGGTGGACCGCCGCTGG | RHBDL1 | ENSG00000103269 | 0.2488387203062592 | [614,479] | [209,312] | 1 | hSpCas9 | negative selection | 4768345 | 676862 | 676884 | 16 | - | 27760321 | HT1080 | viability | ACCGAGGCCATGAACACGGGGG | RHBDL1 | ENSG00000103269 | 0.9446510129505505 | [472,368] | [465,165] | 5 | hSpCas9 | negative selection | 4768346 | 676991 | 677013 | 16 | + | 27760321 | HT1080 | viability | CGGGGCCCGCCTCAACAAGTGG | RHBDL1 | ENSG00000103269 | -0.16365826265984146 | [299,233] | [93,95] | -1 | hSpCas9 | negative selection | 4768347 | 676706 | 676728 | 16 | - | 27760321 | HT29 | viability after 7 days | GCCCGCTGTCCGTTAGCAATGG | RHBDL1 | ENSG00000103269 | 0.5367729563401508 | [653,510] | [1338,896,1058] | 7 | hSpCas9 | negative selection | 4851806 | 676761 | 676783 | 16 | - | 27760321 | HT29 | viability after 7 days | AAACCGCTTGTAGACACCTAGG | RHBDL1 | ENSG00000103269 | 0.3423581146508984 | [594,463] | [892,923,777] | 5 | hSpCas9 | negative selection | 4851807 | 676812 | 676834 | 16 | + | 27760321 | HT29 | viability after 7 days | TTGTGAGGTGGACCGCCGCTGG | RHBDL1 | ENSG00000103269 | -0.4134274024693957 | [614,479] | [765,587,272] | -6 | hSpCas9 | negative selection | 4851808 | 676862 | 676884 | 16 | - | 27760321 | HT29 | viability after 7 days | ACCGAGGCCATGAACACGGGGG | RHBDL1 | ENSG00000103269 | 0.40440690314573446 | [472,368] | [771,410,964] | 6 | hSpCas9 | negative selection | 4851809 | 676991 | 677013 | 16 | + | 27760321 | HT29 | viability after 7 days | CGGGGCCCGCCTCAACAAGTGG | RHBDL1 | ENSG00000103269 | 0.47111968074877736 | [299,233] | [499,413,514] | 7 | hSpCas9 | negative selection | 4851810 | 676706 | 676728 | 16 | - | 27760321 | HT29 | viability after 25 days | GCCCGCTGTCCGTTAGCAATGG | RHBDL1 | ENSG00000103269 | 0.6905953752544797 | [653,510] | [1060,1040,1125] | 7 | hSpCas9 | negative selection | 4935269 | 676761 | 676783 | 16 | - | 27760321 | HT29 | viability after 25 days | AAACCGCTTGTAGACACCTAGG | RHBDL1 | ENSG00000103269 | 0.12142283886649174 | [594,463] | [642,497,853] | 1 | hSpCas9 | negative selection | 4935270 | 676812 | 676834 | 16 | + | 27760321 | HT29 | viability after 25 days | TTGTGAGGTGGACCGCCGCTGG | RHBDL1 | ENSG00000103269 | -0.09975675248314786 | [614,479] | [555,582,616] | -1 | hSpCas9 | negative selection | 4935271 | 676862 | 676884 | 16 | - | 27760321 | HT29 | viability after 25 days | ACCGAGGCCATGAACACGGGGG | RHBDL1 | ENSG00000103269 | 0.19900011888019525 | [472,368] | [528,536,595] | 2 | hSpCas9 | negative selection | 4935272 | 676991 | 677013 | 16 | + | 27760321 | HT29 | viability after 25 days | CGGGGCCCGCCTCAACAAGTGG | RHBDL1 | ENSG00000103269 | 0.44793174838456734 | [299,233] | [377,364,517] | 5 | hSpCas9 | negative selection | 4935273 | 676706 | 676728 | 16 | - | 27760321 | HT29 | viability after 22 days | GCCCGCTGTCCGTTAGCAATGG | RHBDL1 | ENSG00000103269 | 0.6821039656788789 | [653,510] | [1144,888,1206] | 7 | hSpCas9 | negative selection | 5018732 | 676761 | 676783 | 16 | - | 27760321 | HT29 | viability after 22 days | AAACCGCTTGTAGACACCTAGG | RHBDL1 | ENSG00000103269 | 0.05871451947877815 | [594,463] | [706,321,883] | 0 | hSpCas9 | negative selection | 5018733 | 676812 | 676834 | 16 | + | 27760321 | HT29 | viability after 22 days | TTGTGAGGTGGACCGCCGCTGG | RHBDL1 | ENSG00000103269 | 0.3370729782396026 | [614,479] | [944,712,735] | 3 | hSpCas9 | negative selection | 5018734 | 676862 | 676884 | 16 | - | 27760321 | HT29 | viability after 22 days | ACCGAGGCCATGAACACGGGGG | RHBDL1 | ENSG00000103269 | 0.4095555176180118 | [472,368] | [482,682,778] | 4 | hSpCas9 | negative selection | 5018735 | 676991 | 677013 | 16 | + | 27760321 | HT29 | viability after 22 days | CGGGGCCCGCCTCAACAAGTGG | RHBDL1 | ENSG00000103269 | 0.9756824979616261 | [299,233] | [588,565,666] | 9 | hSpCas9 | negative selection | 5018736 | 676706 | 676728 | 16 | - | 27760321 | HT29 | viability after 19 days | GCCCGCTGTCCGTTAGCAATGG | RHBDL1 | ENSG00000103269 | 0.8787602478582736 | [653,510] | [877,1452,1303] | 8 | hSpCas9 | negative selection | 5102195 | 676761 | 676783 | 16 | - | 27760321 | HT29 | viability after 19 days | AAACCGCTTGTAGACACCTAGG | RHBDL1 | ENSG00000103269 | 0.1273028879382201 | [594,463] | [741,609,640] | 1 | hSpCas9 | negative selection | 5102196 | 676812 | 676834 | 16 | + | 27760321 | HT29 | viability after 19 days | TTGTGAGGTGGACCGCCGCTGG | RHBDL1 | ENSG00000103269 | 0.16911067682734726 | [614,479] | [665,612,823] | 1 | hSpCas9 | negative selection | 5102197 | 676862 | 676884 | 16 | - | 27760321 | HT29 | viability after 19 days | ACCGAGGCCATGAACACGGGGG | RHBDL1 | ENSG00000103269 | 0.4327795155009412 | [472,368] | [699,777,482] | 4 | hSpCas9 | negative selection | 5102198 | 676991 | 677013 | 16 | + | 27760321 | HT29 | viability after 19 days | CGGGGCCCGCCTCAACAAGTGG | RHBDL1 | ENSG00000103269 | 0.6420221001897872 | [299,233] | [237,790,378] | 6 | hSpCas9 | negative selection | 5102199 | 676706 | 676728 | 16 | - | 27760321 | HT29 | viability after 16 days | GCCCGCTGTCCGTTAGCAATGG | RHBDL1 | ENSG00000103269 | 0.3694686787961493 | [653,510] | [716,726,1072] | 4 | hSpCas9 | negative selection | 5185658 | 676761 | 676783 | 16 | - | 27760321 | HT29 | viability after 16 days | AAACCGCTTGTAGACACCTAGG | RHBDL1 | ENSG00000103269 | 0.2128005806289257 | [594,463] | [828,568,677] | 2 | hSpCas9 | negative selection | 5185659 | 676812 | 676834 | 16 | + | 27760321 | HT29 | viability after 16 days | TTGTGAGGTGGACCGCCGCTGG | RHBDL1 | ENSG00000103269 | -0.47698212072444757 | [614,479] | [321,557,425] | -5 | hSpCas9 | negative selection | 5185660 | 676862 | 676884 | 16 | - | 27760321 | HT29 | viability after 16 days | ACCGAGGCCATGAACACGGGGG | RHBDL1 | ENSG00000103269 | 0.835874263067935 | [472,368] | [699,867,939] | 8 | hSpCas9 | negative selection | 5185661 | 676991 | 677013 | 16 | + | 27760321 | HT29 | viability after 16 days | CGGGGCCCGCCTCAACAAGTGG | RHBDL1 | ENSG00000103269 | 0.4255606048251128 | [299,233] | [395,478,325] | 5 | hSpCas9 | negative selection | 5185662 | 676706 | 676728 | 16 | - | 27760321 | HT29 | viability after 13 days | GCCCGCTGTCCGTTAGCAATGG | RHBDL1 | ENSG00000103269 | 0.4802666155445915 | [653,510] | [1046,908,875] | 6 | hSpCas9 | negative selection | 5269121 | 676761 | 676783 | 16 | - | 27760321 | HT29 | viability after 13 days | AAACCGCTTGTAGACACCTAGG | RHBDL1 | ENSG00000103269 | 0.05964104424992067 | [594,463] | [578,572,760] | 0 | hSpCas9 | negative selection | 5269122 | 676812 | 676834 | 16 | + | 27760321 | HT29 | viability after 13 days | TTGTGAGGTGGACCGCCGCTGG | RHBDL1 | ENSG00000103269 | 0.07219366642649516 | [614,479] | [545,952,513] | 0 | hSpCas9 | negative selection | 5269123 | 676862 | 676884 | 16 | - | 27760321 | HT29 | viability after 13 days | ACCGAGGCCATGAACACGGGGG | RHBDL1 | ENSG00000103269 | 0.20325930034548334 | [472,368] | [644,503,538] | 2 | hSpCas9 | negative selection | 5269124 | 676991 | 677013 | 16 | + | 27760321 | HT29 | viability after 13 days | CGGGGCCCGCCTCAACAAGTGG | RHBDL1 | ENSG00000103269 | 0.7831790827298417 | [299,233] | [574,645,386] | 8 | hSpCas9 | negative selection | 5269125 | 676706 | 676728 | 16 | - | 27760321 | HT29 | viability after 10 days | GCCCGCTGTCCGTTAGCAATGG | RHBDL1 | ENSG00000103269 | 0.5215312424962307 | [653,510] | [1243,1073,819] | 7 | hSpCas9 | negative selection | 5352584 | 676761 | 676783 | 16 | - | 27760321 | HT29 | viability after 10 days | AAACCGCTTGTAGACACCTAGG | RHBDL1 | ENSG00000103269 | 0.1293572380250082 | [594,463] | [845,624,695] | 1 | hSpCas9 | negative selection | 5352585 | 676812 | 676834 | 16 | + | 27760321 | HT29 | viability after 10 days | TTGTGAGGTGGACCGCCGCTGG | RHBDL1 | ENSG00000103269 | -0.2962084442090567 | [614,479] | [748,369,545] | -4 | hSpCas9 | negative selection | 5352586 | 676862 | 676884 | 16 | - | 27760321 | HT29 | viability after 10 days | ACCGAGGCCATGAACACGGGGG | RHBDL1 | ENSG00000103269 | 0.6818312359113956 | [472,368] | [1053,859,620] | 8 | hSpCas9 | negative selection | 5352587 | 676991 | 677013 | 16 | + | 27760321 | HT29 | viability after 10 days | CGGGGCCCGCCTCAACAAGTGG | RHBDL1 | ENSG00000103269 | 0.454087232883199 | [299,233] | [553,514,305] | 6 | hSpCas9 | negative selection | 5352588 | 676706 | 676728 | 16 | - | 27760321 | MOLM13 | viability | GCCCGCTGTCCGTTAGCAATGG | RHBDL1 | ENSG00000103269 | 0.061328782359612366 | [740,653] | [673,184] | 0 | hSpCas9 | negative selection | 5436047 | 676761 | 676783 | 16 | - | 27760321 | MOLM13 | viability | AAACCGCTTGTAGACACCTAGG | RHBDL1 | ENSG00000103269 | -0.0851179416615454 | [725,594] | [233,447] | 0 | hSpCas9 | negative selection | 5436048 | 676812 | 676834 | 16 | + | 27760321 | MOLM13 | viability | TTGTGAGGTGGACCGCCGCTGG | RHBDL1 | ENSG00000103269 | -0.45540418536580834 | [630,614] | [331,192] | -3 | hSpCas9 | negative selection | 5436049 | 676862 | 676884 | 16 | - | 27760321 | MOLM13 | viability | ACCGAGGCCATGAACACGGGGG | RHBDL1 | ENSG00000103269 | 1.2663213681840741 | [564,472] | [794,621] | 8 | hSpCas9 | negative selection | 5436050 | 676991 | 677013 | 16 | + | 27760321 | MOLM13 | viability | CGGGGCCCGCCTCAACAAGTGG | RHBDL1 | ENSG00000103269 | 0.8529581640517441 | [330,299] | [357,289] | 6 | hSpCas9 | negative selection | 5436051 | 675975 | 675998 | 16 | + | 27661255 | K562 | viability | GACCCCAGGAGAGGACTGACTGG | RHBDL1 | ENSG00000103269 | 0.13489591432225145 | [679,792] | [715,582] | 5 | dCas9-KRAB | negative selection | 5507307 | 676010 | 676033 | 16 | + | 27661255 | K562 | viability | GGCTGGAGAAGGGAGAGTCGGGG | RHBDL1 | ENSG00000103269 | -0.1362916372891838 | [622,731] | [612,386] | -5 | dCas9-KRAB | negative selection | 5507308 | 676113 | 676136 | 16 | + | 27661255 | K562 | viability | GGAAGACGGGGGAACAACTGAGG | RHBDL1 | ENSG00000103269 | -0.002846550554425731 | [1561,1452] | [1265,1149] | 0 | dCas9-KRAB | negative selection | 5507309 | 676122 | 676145 | 16 | + | 27661255 | K562 | viability | GGGAACAACTGAGGAGCTGGAGG | RHBDL1 | ENSG00000103269 | -0.07098631216264517 | [894,964] | [810,616] | -3 | dCas9-KRAB | negative selection | 5507310 | 675926 | 675949 | 16 | - | 27661255 | K562 | viability | GGGATGAGGTAGGTACCGAGCGG | RHBDL1 | ENSG00000103269 | 0.21083657477995477 | [1132,1320] | [1330,960] | 7 | dCas9-KRAB | negative selection | 5507311 | 675777 | 675800 | 16 | + | 27869803 | HPAFII | viability after 27 days | CCCGGCCAGGCTCTATGGACAGG | RHBDL1 | ENSG00000103269 | 0.6111067895804494 | [437] | [306,388,NaN] | 5 | hSpCas9 | negative selection | 9558336 | 676443 | 676466 | 16 | + | 27869803 | HPAFII | viability after 27 days | CCTGGCTCAGAGCAACGAGCAGG | RHBDL1 | ENSG00000103269 | -0.35545459459096596 | [172] | [57,81,NaN] | -3 | hSpCas9 | negative selection | 9558337 | 676824 | 676847 | 16 | - | 27869803 | HPAFII | viability after 27 days | GACGGTAGAAGTACCAGCGGCGG | RHBDL1 | ENSG00000103269 | 0.7846566548415155 | [159] | [25,243,NaN] | 6 | hSpCas9 | negative selection | 9558338 | 677083 | 677106 | 16 | - | 27869803 | HPAFII | viability after 27 days | CATGTAGGTGAGGAAGCGCCAGG | RHBDL1 | ENSG00000103269 | 0.4532908770112931 | [121] | [173,15,NaN] | 3 | hSpCas9 | negative selection | 9558339 | 677360 | 677383 | 16 | - | 27869803 | HPAFII | viability after 27 days | GCACGCCTGCCAGGTAGAGCAGG | RHBDL1 | ENSG00000103269 | 0.417719408895266 | [261] | [255,123,NaN] | 3 | hSpCas9 | negative selection | 9558340 | 677541 | 677564 | 16 | - | 27869803 | HPAFII | viability after 27 days | TTACCATGACAACGTTGGCCAGG | RHBDL1 | ENSG00000103269 | 1.2620262538784697 | [168] | [199,223,NaN] | 9 | hSpCas9 | negative selection | 9558341 | 675777 | 675800 | 16 | + | 27869803 | HPAFII | viability after 15 days | CCCGGCCAGGCTCTATGGACAGG | RHBDL1 | ENSG00000103269 | 0.6068973155108237 | [437] | [875,617,NaN] | 7 | hSpCas9 | negative selection | 9640785 | 676443 | 676466 | 16 | + | 27869803 | HPAFII | viability after 15 days | CCTGGCTCAGAGCAACGAGCAGG | RHBDL1 | ENSG00000103269 | -0.014348077212467891 | [172] | [410,42,NaN] | 0 | hSpCas9 | negative selection | 9640786 | 676824 | 676847 | 16 | - | 27869803 | HPAFII | viability after 15 days | GACGGTAGAAGTACCAGCGGCGG | RHBDL1 | ENSG00000103269 | -0.6611597051265525 | [159] | [6,171,NaN] | -6 | hSpCas9 | negative selection | 9640787 | 677083 | 677106 | 16 | - | 27869803 | HPAFII | viability after 15 days | CATGTAGGTGAGGAAGCGCCAGG | RHBDL1 | ENSG00000103269 | 0.5346206904591756 | [121] | [340,95,NaN] | 6 | hSpCas9 | negative selection | 9640788 | 677360 | 677383 | 16 | - | 27869803 | HPAFII | viability after 15 days | GCACGCCTGCCAGGTAGAGCAGG | RHBDL1 | ENSG00000103269 | 0.3628991711898386 | [261] | [498,276,NaN] | 4 | hSpCas9 | negative selection | 9640789 | 677541 | 677564 | 16 | - | 27869803 | HPAFII | viability after 15 days | TTACCATGACAACGTTGGCCAGG | RHBDL1 | ENSG00000103269 | 0.10039673596276782 | [168] | [219,178,NaN] | 1 | hSpCas9 | negative selection | 9640790 | 675777 | 675800 | 16 | + | 27869803 | ASPC1 | viability after 36 days | CCCGGCCAGGCTCTATGGACAGG | RHBDL1 | ENSG00000103269 | -0.28021360208853907 | [1212] | [212,227,535] | -3 | hSpCas9 | negative selection | 9723234 | 676443 | 676466 | 16 | + | 27869803 | ASPC1 | viability after 36 days | CCTGGCTCAGAGCAACGAGCAGG | RHBDL1 | ENSG00000103269 | -0.04496733489386717 | [331] | [28,97,180] | 0 | hSpCas9 | negative selection | 9723235 | 676824 | 676847 | 16 | - | 27869803 | ASPC1 | viability after 36 days | GACGGTAGAAGTACCAGCGGCGG | RHBDL1 | ENSG00000103269 | 0.9149623088058858 | [483] | [575,113,296] | 8 | hSpCas9 | negative selection | 9723236 | 677083 | 677106 | 16 | - | 27869803 | ASPC1 | viability after 36 days | CATGTAGGTGAGGAAGCGCCAGG | RHBDL1 | ENSG00000103269 | -1.23532319238461 | [358] | [46,114,7] | -8 | hSpCas9 | negative selection | 9723237 | 677360 | 677383 | 16 | - | 27869803 | ASPC1 | viability after 36 days | GCACGCCTGCCAGGTAGAGCAGG | RHBDL1 | ENSG00000103269 | -0.8624726276418602 | [714] | [121,239,64] | -7 | hSpCas9 | negative selection | 9723238 | 677541 | 677564 | 16 | - | 27869803 | ASPC1 | viability after 36 days | TTACCATGACAACGTTGGCCAGG | RHBDL1 | ENSG00000103269 | -0.5559326986936992 | [536] | [112,297,0] | -5 | hSpCas9 | negative selection | 9723239 | 675777 | 675800 | 16 | + | 27869803 | PATU8988S | viability after 35 days | CCCGGCCAGGCTCTATGGACAGG | RHBDL1 | ENSG00000103269 | -0.24593315405367844 | [850] | [298,278,NaN] | -3 | hSpCas9 | negative selection | 9805683 | 676443 | 676466 | 16 | + | 27869803 | PATU8988S | viability after 35 days | CCTGGCTCAGAGCAACGAGCAGG | RHBDL1 | ENSG00000103269 | -0.9678602667476763 | [290] | [24,94,NaN] | -7 | hSpCas9 | negative selection | 9805684 | 676824 | 676847 | 16 | - | 27869803 | PATU8988S | viability after 35 days | GACGGTAGAAGTACCAGCGGCGG | RHBDL1 | ENSG00000103269 | 0.1814714109436334 | [303] | [71,205,NaN] | 2 | hSpCas9 | negative selection | 9805685 | 677083 | 677106 | 16 | - | 27869803 | PATU8988S | viability after 35 days | CATGTAGGTGAGGAAGCGCCAGG | RHBDL1 | ENSG00000103269 | 0.5149091993031378 | [372] | [283,144,NaN] | 6 | hSpCas9 | negative selection | 9805686 | 677360 | 677383 | 16 | - | 27869803 | PATU8988S | viability after 35 days | GCACGCCTGCCAGGTAGAGCAGG | RHBDL1 | ENSG00000103269 | -0.4462035507124268 | [520] | [158,148,NaN] | -4 | hSpCas9 | negative selection | 9805687 | 677541 | 677564 | 16 | - | 27869803 | PATU8988S | viability after 35 days | TTACCATGACAACGTTGGCCAGG | RHBDL1 | ENSG00000103269 | 0.5191806492612068 | [512] | [340,250,NaN] | 6 | hSpCas9 | negative selection | 9805688 | 675777 | 675800 | 16 | + | 27869803 | PATU8988S | viability after 31 days | CCCGGCCAGGCTCTATGGACAGG | RHBDL1 | ENSG00000103269 | -0.2017995640926919 | [850] | [276,317,NaN] | -2 | hSpCas9 | negative selection | 9888132 | 676443 | 676466 | 16 | + | 27869803 | PATU8988S | viability after 31 days | CCTGGCTCAGAGCAACGAGCAGG | RHBDL1 | ENSG00000103269 | -0.6909843162163236 | [290] | [48,100,NaN] | -6 | hSpCas9 | negative selection | 9888133 | 676824 | 676847 | 16 | - | 27869803 | PATU8988S | viability after 31 days | GACGGTAGAAGTACCAGCGGCGG | RHBDL1 | ENSG00000103269 | 0.30493548630821166 | [303] | [92,221,NaN] | 4 | hSpCas9 | negative selection | 9888134 | 677083 | 677106 | 16 | - | 27869803 | PATU8988S | viability after 31 days | CATGTAGGTGAGGAAGCGCCAGG | RHBDL1 | ENSG00000103269 | 0.24682072570051633 | [372] | [190,157,NaN] | 3 | hSpCas9 | negative selection | 9888135 | 677360 | 677383 | 16 | - | 27869803 | PATU8988S | viability after 31 days | GCACGCCTGCCAGGTAGAGCAGG | RHBDL1 | ENSG00000103269 | -0.17704967673678665 | [520] | [148,227,NaN] | -2 | hSpCas9 | negative selection | 9888136 | 677541 | 677564 | 16 | - | 27869803 | PATU8988S | viability after 31 days | TTACCATGACAACGTTGGCCAGG | RHBDL1 | ENSG00000103269 | 0.1167411819497165 | [512] | [201,246,NaN] | 1 | hSpCas9 | negative selection | 9888137 | 675777 | 675800 | 16 | + | 27869803 | HPAFII | viability after 35 days | CCCGGCCAGGCTCTATGGACAGG | RHBDL1 | ENSG00000103269 | 0.04951517266475747 | [437] | [125,345,NaN] | 0 | hSpCas9 | negative selection | 9970581 | 676443 | 676466 | 16 | + | 27869803 | HPAFII | viability after 35 days | CCTGGCTCAGAGCAACGAGCAGG | RHBDL1 | ENSG00000103269 | -3.2450912305515343 | [172] | [12,4,NaN] | -8 | hSpCas9 | negative selection | 9970582 | 676824 | 676847 | 16 | - | 27869803 | HPAFII | viability after 35 days | GACGGTAGAAGTACCAGCGGCGG | RHBDL1 | ENSG00000103269 | 0.5964957916019031 | [159] | [10,247,NaN] | 4 | hSpCas9 | negative selection | 9970583 | 677083 | 677106 | 16 | - | 27869803 | HPAFII | viability after 35 days | CATGTAGGTGAGGAAGCGCCAGG | RHBDL1 | ENSG00000103269 | -0.43030274119912426 | [121] | [66,21,NaN] | -3 | hSpCas9 | negative selection | 9970584 | 677360 | 677383 | 16 | - | 27869803 | HPAFII | viability after 35 days | GCACGCCTGCCAGGTAGAGCAGG | RHBDL1 | ENSG00000103269 | 0.8897885684181305 | [261] | [241,249,NaN] | 6 | hSpCas9 | negative selection | 9970585 | 677541 | 677564 | 16 | - | 27869803 | HPAFII | viability after 35 days | TTACCATGACAACGTTGGCCAGG | RHBDL1 | ENSG00000103269 | 0.9629315910480034 | [168] | [59,286,NaN] | 6 | hSpCas9 | negative selection | 9970586 | 675777 | 675800 | 16 | + | 27869803 | HPAFII | viability after 31 days | CCCGGCCAGGCTCTATGGACAGG | RHBDL1 | ENSG00000103269 | 0.4654572567097699 | [437] | [247,438,NaN] | 3 | hSpCas9 | negative selection | 10053030 | 676443 | 676466 | 16 | + | 27869803 | HPAFII | viability after 31 days | CCTGGCTCAGAGCAACGAGCAGG | RHBDL1 | ENSG00000103269 | -1.0873602769808848 | [172] | [49,40,NaN] | -6 | hSpCas9 | negative selection | 10053031 | 676824 | 676847 | 16 | - | 27869803 | HPAFII | viability after 31 days | GACGGTAGAAGTACCAGCGGCGG | RHBDL1 | ENSG00000103269 | 0.5951123728797887 | [159] | [15,265,NaN] | 4 | hSpCas9 | negative selection | 10053032 | 677083 | 677106 | 16 | - | 27869803 | HPAFII | viability after 31 days | CATGTAGGTGAGGAAGCGCCAGG | RHBDL1 | ENSG00000103269 | -1.0845420975300448 | [121] | [60,0,NaN] | -6 | hSpCas9 | negative selection | 10053033 | 677360 | 677383 | 16 | - | 27869803 | HPAFII | viability after 31 days | GCACGCCTGCCAGGTAGAGCAGG | RHBDL1 | ENSG00000103269 | 0.3966704123214371 | [261] | [183,203,NaN] | 3 | hSpCas9 | negative selection | 10053034 | 677541 | 677564 | 16 | - | 27869803 | HPAFII | viability after 31 days | TTACCATGACAACGTTGGCCAGG | RHBDL1 | ENSG00000103269 | 0.7745029171153789 | [168] | [55,277,NaN] | 5 | hSpCas9 | negative selection | 10053035 | 676350 | 676373 | 16 | + | 28162770 | P31FUJ | viability | GAACACAGGCTTCATCGGTGCGG | RHBDL1 | ENSG00000103269 | 0.2873671547995795 | [2572] | [3689] | 3 | hSpCas9 | negative selection | 10224954 | 676744 | 676767 | 16 | - | 28162770 | P31FUJ | viability | CCTAGGCCTGGCTCATCCAGCGG | RHBDL1 | ENSG00000103269 | 0.10907547981722843 | [1263] | [1601] | 1 | hSpCas9 | negative selection | 10224955 | 676376 | 676399 | 16 | - | 28162770 | P31FUJ | viability | GCTGTGCACCAGGCCAGTGAAGG | RHBDL1 | ENSG00000103269 | -1.01670702153914 | [1311] | [761] | -6 | hSpCas9 | negative selection | 10224956 | 676824 | 676847 | 16 | - | 28162770 | P31FUJ | viability | GACGGTAGAAGTACCAGCGGCGG | RHBDL1 | ENSG00000103269 | 0.017236879451856923 | [538] | [640] | 0 | hSpCas9 | negative selection | 10224957 | 676997 | 677020 | 16 | - | 28162770 | P31FUJ | viability | GCAGCACCCACTTGTTGAGGCGG | RHBDL1 | ENSG00000103269 | 0.2478721916469775 | [2475] | [3454] | 2 | hSpCas9 | negative selection | 10224958 | 677077 | 677100 | 16 | - | 28162770 | P31FUJ | viability | GGTGAGGAAGCGCCAGGCGCGGG | RHBDL1 | ENSG00000103269 | 0.06718333759230657 | [211] | [260] | 0 | hSpCas9 | negative selection | 10224959 | 675808 | 675831 | 16 | + | 28162770 | P31FUJ | viability | GCTGCAGCTCATCCAGGAGCAGG | RHBDL1 | ENSG00000103269 | -0.312091114219018 | [373] | [353] | -3 | hSpCas9 | negative selection | 10224960 | 676419 | 676442 | 16 | + | 28162770 | P31FUJ | viability | GGCCAAGCTGGACATGCTGGTGG | RHBDL1 | ENSG00000103269 | -0.1438433322241517 | [1870] | [1989] | -1 | hSpCas9 | negative selection | 10224961 | 676470 | 676493 | 16 | + | 28162770 | P31FUJ | viability | GGTCTGCTACCAGGAGCTGGTGG | RHBDL1 | ENSG00000103269 | -0.395652680096421 | [355] | [317] | -4 | hSpCas9 | negative selection | 10224962 | 676703 | 676726 | 16 | + | 28162770 | P31FUJ | viability | GGGCCATTGCTAACGGACAGCGG | RHBDL1 | ENSG00000103269 | 0.3687909708508983 | [459] | [697] | 4 | hSpCas9 | negative selection | 10224963 | 676350 | 676373 | 16 | + | 28162770 | TF1 | viability | GAACACAGGCTTCATCGGTGCGG | RHBDL1 | ENSG00000103269 | NaN | [NaN] | [459] | 1 | hSpCas9 | negative selection | 10394320 | 676744 | 676767 | 16 | - | 28162770 | TF1 | viability | CCTAGGCCTGGCTCATCCAGCGG | RHBDL1 | ENSG00000103269 | NaN | [NaN] | [150] | 1 | hSpCas9 | negative selection | 10394321 | 676376 | 676399 | 16 | - | 28162770 | TF1 | viability | GCTGTGCACCAGGCCAGTGAAGG | RHBDL1 | ENSG00000103269 | NaN | [NaN] | [145] | 1 | hSpCas9 | negative selection | 10394322 | 676824 | 676847 | 16 | - | 28162770 | TF1 | viability | GACGGTAGAAGTACCAGCGGCGG | RHBDL1 | ENSG00000103269 | NaN | [NaN] | [101] | 1 | hSpCas9 | negative selection | 10394323 | 676997 | 677020 | 16 | - | 28162770 | TF1 | viability | GCAGCACCCACTTGTTGAGGCGG | RHBDL1 | ENSG00000103269 | NaN | [NaN] | [364] | 1 | hSpCas9 | negative selection | 10394324 | 677077 | 677100 | 16 | - | 28162770 | TF1 | viability | GGTGAGGAAGCGCCAGGCGCGGG | RHBDL1 | ENSG00000103269 | NaN | [NaN] | [111] | 1 | hSpCas9 | negative selection | 10394325 | 675808 | 675831 | 16 | + | 28162770 | TF1 | viability | GCTGCAGCTCATCCAGGAGCAGG | RHBDL1 | ENSG00000103269 | NaN | [NaN] | [33] | 1 | hSpCas9 | negative selection | 10394326 | 676419 | 676442 | 16 | + | 28162770 | TF1 | viability | GGCCAAGCTGGACATGCTGGTGG | RHBDL1 | ENSG00000103269 | NaN | [NaN] | [182] | 1 | hSpCas9 | negative selection | 10394327 | 676470 | 676493 | 16 | + | 28162770 | TF1 | viability | GGTCTGCTACCAGGAGCTGGTGG | RHBDL1 | ENSG00000103269 | NaN | [NaN] | [86] | 1 | hSpCas9 | negative selection | 10394328 | 676703 | 676726 | 16 | + | 28162770 | TF1 | viability | GGGCCATTGCTAACGGACAGCGG | RHBDL1 | ENSG00000103269 | NaN | [NaN] | [205] | 1 | hSpCas9 | negative selection | 10394329 | 676350 | 676373 | 16 | + | 28162770 | SKM1 | viability | GAACACAGGCTTCATCGGTGCGG | RHBDL1 | ENSG00000103269 | -0.0048657551718158665 | [188] | [332] | 0 | hSpCas9 | negative selection | 10563686 | 676744 | 676767 | 16 | - | 28162770 | SKM1 | viability | CCTAGGCCTGGCTCATCCAGCGG | RHBDL1 | ENSG00000103269 | -0.503472179596508 | [84] | [105] | -4 | hSpCas9 | negative selection | 10563687 | 676376 | 676399 | 16 | - | 28162770 | SKM1 | viability | GCTGTGCACCAGGCCAGTGAAGG | RHBDL1 | ENSG00000103269 | -1.3684900509285263 | [110] | [75] | -7 | hSpCas9 | negative selection | 10563688 | 676824 | 676847 | 16 | - | 28162770 | SKM1 | viability | GACGGTAGAAGTACCAGCGGCGG | RHBDL1 | ENSG00000103269 | -0.6597302691231285 | [41] | [46] | -5 | hSpCas9 | negative selection | 10563689 | 676997 | 677020 | 16 | - | 28162770 | SKM1 | viability | GCAGCACCCACTTGTTGAGGCGG | RHBDL1 | ENSG00000103269 | -0.36632221424581557 | [174] | [239] | -3 | hSpCas9 | negative selection | 10563690 | 677077 | 677100 | 16 | - | 28162770 | SKM1 | viability | GGTGAGGAAGCGCCAGGCGCGGG | RHBDL1 | ENSG00000103269 | 0.025995208532944458 | [14] | [26] | 0 | hSpCas9 | negative selection | 10563691 | 675808 | 675831 | 16 | + | 28162770 | SKM1 | viability | GCTGCAGCTCATCCAGGAGCAGG | RHBDL1 | ENSG00000103269 | 0.4003907233144426 | [23] | [55] | 4 | hSpCas9 | negative selection | 10563692 | 676419 | 676442 | 16 | + | 28162770 | SKM1 | viability | GGCCAAGCTGGACATGCTGGTGG | RHBDL1 | ENSG00000103269 | 0.11526254663003166 | [140] | [269] | 1 | hSpCas9 | negative selection | 10563693 | 676470 | 676493 | 16 | + | 28162770 | SKM1 | viability | GGTCTGCTACCAGGAGCTGGTGG | RHBDL1 | ENSG00000103269 | 0.08488889758651319 | [23] | [44] | 0 | hSpCas9 | negative selection | 10563694 | 676703 | 676726 | 16 | + | 28162770 | SKM1 | viability | GGGCCATTGCTAACGGACAGCGG | RHBDL1 | ENSG00000103269 | -0.09209086138974976 | [40] | [67] | -1 | hSpCas9 | negative selection | 10563695 | 676350 | 676373 | 16 | + | 28162770 | SKM1 | viability | GAACACAGGCTTCATCGGTGCGG | RHBDL1 | ENSG00000103269 | -0.0048657551718158665 | [188] | [332] | 0 | hSpCas9 | negative selection | 10733052 | 676744 | 676767 | 16 | - | 28162770 | SKM1 | viability | CCTAGGCCTGGCTCATCCAGCGG | RHBDL1 | ENSG00000103269 | -0.503472179596508 | [84] | [105] | -4 | hSpCas9 | negative selection | 10733053 | 676376 | 676399 | 16 | - | 28162770 | SKM1 | viability | GCTGTGCACCAGGCCAGTGAAGG | RHBDL1 | ENSG00000103269 | -1.3684900509285263 | [110] | [75] | -7 | hSpCas9 | negative selection | 10733054 | 676824 | 676847 | 16 | - | 28162770 | SKM1 | viability | GACGGTAGAAGTACCAGCGGCGG | RHBDL1 | ENSG00000103269 | -0.6597302691231285 | [41] | [46] | -5 | hSpCas9 | negative selection | 10733055 | 676997 | 677020 | 16 | - | 28162770 | SKM1 | viability | GCAGCACCCACTTGTTGAGGCGG | RHBDL1 | ENSG00000103269 | -0.36632221424581557 | [174] | [239] | -3 | hSpCas9 | negative selection | 10733056 | 677077 | 677100 | 16 | - | 28162770 | SKM1 | viability | GGTGAGGAAGCGCCAGGCGCGGG | RHBDL1 | ENSG00000103269 | 0.025995208532944458 | [14] | [26] | 0 | hSpCas9 | negative selection | 10733057 | 675808 | 675831 | 16 | + | 28162770 | SKM1 | viability | GCTGCAGCTCATCCAGGAGCAGG | RHBDL1 | ENSG00000103269 | 0.4003907233144426 | [23] | [55] | 4 | hSpCas9 | negative selection | 10733058 | 676419 | 676442 | 16 | + | 28162770 | SKM1 | viability | GGCCAAGCTGGACATGCTGGTGG | RHBDL1 | ENSG00000103269 | 0.11526254663003166 | [140] | [269] | 1 | hSpCas9 | negative selection | 10733059 | 676470 | 676493 | 16 | + | 28162770 | SKM1 | viability | GGTCTGCTACCAGGAGCTGGTGG | RHBDL1 | ENSG00000103269 | 0.08488889758651319 | [23] | [44] | 0 | hSpCas9 | negative selection | 10733060 | 676703 | 676726 | 16 | + | 28162770 | SKM1 | viability | GGGCCATTGCTAACGGACAGCGG | RHBDL1 | ENSG00000103269 | -0.09209086138974976 | [40] | [67] | -1 | hSpCas9 | negative selection | 10733061 | 676350 | 676373 | 16 | + | 28162770 | PL21 | viability | GAACACAGGCTTCATCGGTGCGG | RHBDL1 | ENSG00000103269 | -0.6703007517417637 | [595] | [162] | -5 | hSpCas9 | negative selection | 10902418 | 676744 | 676767 | 16 | - | 28162770 | PL21 | viability | CCTAGGCCTGGCTCATCCAGCGG | RHBDL1 | ENSG00000103269 | -0.5958464934890867 | [315] | [90] | -4 | hSpCas9 | negative selection | 10902419 | 676376 | 676399 | 16 | - | 28162770 | PL21 | viability | GCTGTGCACCAGGCCAGTGAAGG | RHBDL1 | ENSG00000103269 | -0.5448187704304166 | [361] | [107] | -4 | hSpCas9 | negative selection | 10902420 | 676824 | 676847 | 16 | - | 28162770 | PL21 | viability | GACGGTAGAAGTACCAGCGGCGG | RHBDL1 | ENSG00000103269 | -0.23874462674389152 | [121] | [44] | -2 | hSpCas9 | negative selection | 10902421 | 676997 | 677020 | 16 | - | 28162770 | PL21 | viability | GCAGCACCCACTTGTTGAGGCGG | RHBDL1 | ENSG00000103269 | 0.1490654298950509 | [689] | [332] | 1 | hSpCas9 | negative selection | 10902422 | 677077 | 677100 | 16 | - | 28162770 | PL21 | viability | GGTGAGGAAGCGCCAGGCGCGGG | RHBDL1 | ENSG00000103269 | -0.18452423574600507 | [46] | [17] | -1 | hSpCas9 | negative selection | 10902423 | 675808 | 675831 | 16 | + | 28162770 | PL21 | viability | GCTGCAGCTCATCCAGGAGCAGG | RHBDL1 | ENSG00000103269 | 0.3851715083218409 | [94] | [53] | 3 | hSpCas9 | negative selection | 10902424 | 676419 | 676442 | 16 | + | 28162770 | PL21 | viability | GGCCAAGCTGGACATGCTGGTGG | RHBDL1 | ENSG00000103269 | 0.1330254186307831 | [439] | [209] | 1 | hSpCas9 | negative selection | 10902425 | 676470 | 676493 | 16 | + | 28162770 | PL21 | viability | GGTCTGCTACCAGGAGCTGGTGG | RHBDL1 | ENSG00000103269 | 0.13142686440530582 | [85] | [40] | 1 | hSpCas9 | negative selection | 10902426 | 676703 | 676726 | 16 | + | 28162770 | PL21 | viability | GGGCCATTGCTAACGGACAGCGG | RHBDL1 | ENSG00000103269 | -0.3249514302544374 | [117] | [40] | -2 | hSpCas9 | negative selection | 10902427 | 676350 | 676373 | 16 | + | 28162770 | P31FUJ | viability | GAACACAGGCTTCATCGGTGCGG | RHBDL1 | ENSG00000103269 | 0.2873671547995795 | [2572] | [3689] | 3 | hSpCas9 | negative selection | 11071784 | 676744 | 676767 | 16 | - | 28162770 | P31FUJ | viability | CCTAGGCCTGGCTCATCCAGCGG | RHBDL1 | ENSG00000103269 | 0.10907547981722843 | [1263] | [1601] | 1 | hSpCas9 | negative selection | 11071785 | 676376 | 676399 | 16 | - | 28162770 | P31FUJ | viability | GCTGTGCACCAGGCCAGTGAAGG | RHBDL1 | ENSG00000103269 | -1.01670702153914 | [1311] | [761] | -6 | hSpCas9 | negative selection | 11071786 | 676824 | 676847 | 16 | - | 28162770 | P31FUJ | viability | GACGGTAGAAGTACCAGCGGCGG | RHBDL1 | ENSG00000103269 | 0.017236879451856923 | [538] | [640] | 0 | hSpCas9 | negative selection | 11071787 | 676997 | 677020 | 16 | - | 28162770 | P31FUJ | viability | GCAGCACCCACTTGTTGAGGCGG | RHBDL1 | ENSG00000103269 | 0.2478721916469775 | [2475] | [3454] | 2 | hSpCas9 | negative selection | 11071788 | 677077 | 677100 | 16 | - | 28162770 | P31FUJ | viability | GGTGAGGAAGCGCCAGGCGCGGG | RHBDL1 | ENSG00000103269 | 0.06718333759230657 | [211] | [260] | 0 | hSpCas9 | negative selection | 11071789 | 675808 | 675831 | 16 | + | 28162770 | P31FUJ | viability | GCTGCAGCTCATCCAGGAGCAGG | RHBDL1 | ENSG00000103269 | -0.312091114219018 | [373] | [353] | -3 | hSpCas9 | negative selection | 11071790 | 676419 | 676442 | 16 | + | 28162770 | P31FUJ | viability | GGCCAAGCTGGACATGCTGGTGG | RHBDL1 | ENSG00000103269 | -0.1438433322241517 | [1870] | [1989] | -1 | hSpCas9 | negative selection | 11071791 | 676470 | 676493 | 16 | + | 28162770 | P31FUJ | viability | GGTCTGCTACCAGGAGCTGGTGG | RHBDL1 | ENSG00000103269 | -0.395652680096421 | [355] | [317] | -4 | hSpCas9 | negative selection | 11071792 | 676703 | 676726 | 16 | + | 28162770 | P31FUJ | viability | GGGCCATTGCTAACGGACAGCGG | RHBDL1 | ENSG00000103269 | 0.3687909708508983 | [459] | [697] | 4 | hSpCas9 | negative selection | 11071793 | 676350 | 676373 | 16 | + | 28162770 | OCIAML5 | viability | GAACACAGGCTTCATCGGTGCGG | RHBDL1 | ENSG00000103269 | -0.3861432406749281 | [382] | [528] | -3 | hSpCas9 | negative selection | 11241150 | 676744 | 676767 | 16 | - | 28162770 | OCIAML5 | viability | CCTAGGCCTGGCTCATCCAGCGG | RHBDL1 | ENSG00000103269 | 0.235989605801199 | [142] | [303] | 2 | hSpCas9 | negative selection | 11241151 | 676376 | 676399 | 16 | - | 28162770 | OCIAML5 | viability | GCTGTGCACCAGGCCAGTGAAGG | RHBDL1 | ENSG00000103269 | -0.6132797112768804 | [149] | [176] | -4 | hSpCas9 | negative selection | 11241152 | 676824 | 676847 | 16 | - | 28162770 | OCIAML5 | viability | GACGGTAGAAGTACCAGCGGCGG | RHBDL1 | ENSG00000103269 | -1.1179606308370316 | [100] | [83] | -6 | hSpCas9 | negative selection | 11241153 | 676997 | 677020 | 16 | - | 28162770 | OCIAML5 | viability | GCAGCACCCACTTGTTGAGGCGG | RHBDL1 | ENSG00000103269 | 0.7972647489768789 | [262] | [824] | 7 | hSpCas9 | negative selection | 11241154 | 677077 | 677100 | 16 | - | 28162770 | OCIAML5 | viability | GGTGAGGAAGCGCCAGGCGCGGG | RHBDL1 | ENSG00000103269 | -0.5968095156219222 | [30] | [36] | -4 | hSpCas9 | negative selection | 11241155 | 675808 | 675831 | 16 | + | 28162770 | OCIAML5 | viability | GCTGCAGCTCATCCAGGAGCAGG | RHBDL1 | ENSG00000103269 | -0.8351927522996008 | [84] | [85] | -5 | hSpCas9 | negative selection | 11241156 | 676419 | 676442 | 16 | + | 28162770 | OCIAML5 | viability | GGCCAAGCTGGACATGCTGGTGG | RHBDL1 | ENSG00000103269 | -0.102610032514594 | [275] | [463] | 0 | hSpCas9 | negative selection | 11241157 | 676470 | 676493 | 16 | + | 28162770 | OCIAML5 | viability | GGTCTGCTACCAGGAGCTGGTGG | RHBDL1 | ENSG00000103269 | -0.2541650144353427 | [36] | [55] | -2 | hSpCas9 | negative selection | 11241158 | 676703 | 676726 | 16 | + | 28162770 | OCIAML5 | viability | GGGCCATTGCTAACGGACAGCGG | RHBDL1 | ENSG00000103269 | 0.4240578344102405 | [63] | [154] | 3 | hSpCas9 | negative selection | 11241159 | 676350 | 676373 | 16 | + | 28162770 | EOL1 | viability | GAACACAGGCTTCATCGGTGCGG | RHBDL1 | ENSG00000103269 | 0.2432875888268493 | [905] | [564] | 2 | hSpCas9 | negative selection | 11410516 | 676744 | 676767 | 16 | - | 28162770 | EOL1 | viability | CCTAGGCCTGGCTCATCCAGCGG | RHBDL1 | ENSG00000103269 | -0.5215166233289337 | [375] | [137] | -4 | hSpCas9 | negative selection | 11410517 | 676376 | 676399 | 16 | - | 28162770 | EOL1 | viability | GCTGTGCACCAGGCCAGTGAAGG | RHBDL1 | ENSG00000103269 | -0.20882983409306827 | [418] | [190] | -1 | hSpCas9 | negative selection | 11410518 | 676824 | 676847 | 16 | - | 28162770 | EOL1 | viability | GACGGTAGAAGTACCAGCGGCGG | RHBDL1 | ENSG00000103269 | -0.23895096071234478 | [167] | [74] | -2 | hSpCas9 | negative selection | 11410519 | 676997 | 677020 | 16 | - | 28162770 | EOL1 | viability | GCAGCACCCACTTGTTGAGGCGG | RHBDL1 | ENSG00000103269 | -0.36125215784995657 | [906] | [371] | -3 | hSpCas9 | negative selection | 11410520 | 677077 | 677100 | 16 | - | 28162770 | EOL1 | viability | GGTGAGGAAGCGCCAGGCGCGGG | RHBDL1 | ENSG00000103269 | 0.5736406097114064 | [87] | [68] | 5 | hSpCas9 | negative selection | 11410521 | 675808 | 675831 | 16 | + | 28162770 | EOL1 | viability | GCTGCAGCTCATCCAGGAGCAGG | RHBDL1 | ENSG00000103269 | -0.023921927789383624 | [109] | [56] | 0 | hSpCas9 | negative selection | 11410522 | 676419 | 676442 | 16 | + | 28162770 | EOL1 | viability | GGCCAAGCTGGACATGCTGGTGG | RHBDL1 | ENSG00000103269 | -0.2045973797294428 | [653] | [298] | -1 | hSpCas9 | negative selection | 11410523 | 676470 | 676493 | 16 | + | 28162770 | EOL1 | viability | GGTCTGCTACCAGGAGCTGGTGG | RHBDL1 | ENSG00000103269 | -1.0242269050742923 | [165] | [42] | -6 | hSpCas9 | negative selection | 11410524 | 676703 | 676726 | 16 | + | 28162770 | EOL1 | viability | GGGCCATTGCTAACGGACAGCGG | RHBDL1 | ENSG00000103269 | 0.7180968941031082 | [194] | [168] | 6 | hSpCas9 | negative selection | 11410525 | 676350 | 676373 | 16 | + | 28162770 | MOLM13 | viability | GAACACAGGCTTCATCGGTGCGG | RHBDL1 | ENSG00000103269 | 0.6777589692394697 | [842] | [974] | 5 | hSpCas9 | negative selection | 11579882 | 676744 | 676767 | 16 | - | 28162770 | MOLM13 | viability | CCTAGGCCTGGCTCATCCAGCGG | RHBDL1 | ENSG00000103269 | -0.49677754534314056 | [362] | [185] | -3 | hSpCas9 | negative selection | 11579883 | 676376 | 676399 | 16 | - | 28162770 | MOLM13 | viability | GCTGTGCACCAGGCCAGTGAAGG | RHBDL1 | ENSG00000103269 | -1.6848138793691467 | [457] | [102] | -7 | hSpCas9 | negative selection | 11579884 | 676824 | 676847 | 16 | - | 28162770 | MOLM13 | viability | GACGGTAGAAGTACCAGCGGCGG | RHBDL1 | ENSG00000103269 | 0.7922401386987967 | [118] | [148] | 6 | hSpCas9 | negative selection | 11579885 | 676997 | 677020 | 16 | - | 28162770 | MOLM13 | viability | GCAGCACCCACTTGTTGAGGCGG | RHBDL1 | ENSG00000103269 | 0.9520111927589074 | [789] | [1104] | 7 | hSpCas9 | negative selection | 11579886 | 677077 | 677100 | 16 | - | 28162770 | MOLM13 | viability | GGTGAGGAAGCGCCAGGCGCGGG | RHBDL1 | ENSG00000103269 | 0.7695450814056799 | [42] | [52] | 6 | hSpCas9 | negative selection | 11579887 | 675808 | 675831 | 16 | + | 28162770 | MOLM13 | viability | GCTGCAGCTCATCCAGGAGCAGG | RHBDL1 | ENSG00000103269 | 1.4137336114976733 | [94] | [182] | 9 | hSpCas9 | negative selection | 11579888 | 676419 | 676442 | 16 | + | 28162770 | MOLM13 | viability | GGCCAAGCTGGACATGCTGGTGG | RHBDL1 | ENSG00000103269 | 0.2958447731964431 | [595] | [528] | 2 | hSpCas9 | negative selection | 11579889 | 676470 | 676493 | 16 | + | 28162770 | MOLM13 | viability | GGTCTGCTACCAGGAGCTGGTGG | RHBDL1 | ENSG00000103269 | -0.6316462920063355 | [119] | [55] | -4 | hSpCas9 | negative selection | 11579890 | 676703 | 676726 | 16 | + | 28162770 | MOLM13 | viability | GGGCCATTGCTAACGGACAGCGG | RHBDL1 | ENSG00000103269 | -0.388985676356824 | [162] | [89] | -2 | hSpCas9 | negative selection | 11579891 | 676350 | 676373 | 16 | + | 28162770 | HEL | viability | GAACACAGGCTTCATCGGTGCGG | RHBDL1 | ENSG00000103269 | -0.20053566431219005 | [792] | [441] | -1 | hSpCas9 | negative selection | 11749248 | 676744 | 676767 | 16 | - | 28162770 | HEL | viability | CCTAGGCCTGGCTCATCCAGCGG | RHBDL1 | ENSG00000103269 | 0.8822047666957462 | [287] | [339] | 7 | hSpCas9 | negative selection | 11749249 | 676376 | 676399 | 16 | - | 28162770 | HEL | viability | GCTGTGCACCAGGCCAGTGAAGG | RHBDL1 | ENSG00000103269 | -1.5200441001979357 | [402] | [89] | -7 | hSpCas9 | negative selection | 11749250 | 676824 | 676847 | 16 | - | 28162770 | HEL | viability | GACGGTAGAAGTACCAGCGGCGG | RHBDL1 | ENSG00000103269 | 0.698954841566905 | [150] | [156] | 6 | hSpCas9 | negative selection | 11749251 | 676997 | 677020 | 16 | - | 28162770 | HEL | viability | GCAGCACCCACTTGTTGAGGCGG | RHBDL1 | ENSG00000103269 | -0.7473447399462053 | [725] | [276] | -5 | hSpCas9 | negative selection | 11749252 | 677077 | 677100 | 16 | - | 28162770 | HEL | viability | GGTGAGGAAGCGCCAGGCGCGGG | RHBDL1 | ENSG00000103269 | 0.8503342514087244 | [83] | [96] | 7 | hSpCas9 | negative selection | 11749253 | 675808 | 675831 | 16 | + | 28162770 | HEL | viability | GCTGCAGCTCATCCAGGAGCAGG | RHBDL1 | ENSG00000103269 | -0.835308464804287 | [116] | [41] | -5 | hSpCas9 | negative selection | 11749254 | 676419 | 676442 | 16 | + | 28162770 | HEL | viability | GGCCAAGCTGGACATGCTGGTGG | RHBDL1 | ENSG00000103269 | 0.738316491982588 | [510] | [545] | 6 | hSpCas9 | negative selection | 11749255 | 676470 | 676493 | 16 | + | 28162770 | HEL | viability | GGTCTGCTACCAGGAGCTGGTGG | RHBDL1 | ENSG00000103269 | 0.9057732378341506 | [94] | [113] | 7 | hSpCas9 | negative selection | 11749256 | 676703 | 676726 | 16 | + | 28162770 | HEL | viability | GGGCCATTGCTAACGGACAGCGG | RHBDL1 | ENSG00000103269 | 0.7056700877268138 | [156] | [163] | 6 | hSpCas9 | negative selection | 11749257 | 676350 | 676373 | 16 | + | 28162770 | MV411 | viability | GAACACAGGCTTCATCGGTGCGG | RHBDL1 | ENSG00000103269 | 0.188959085517046 | [578] | [555] | 1 | hSpCas9 | negative selection | 11918614 | 676744 | 676767 | 16 | - | 28162770 | MV411 | viability | CCTAGGCCTGGCTCATCCAGCGG | RHBDL1 | ENSG00000103269 | -1.3103034812033565 | [314] | [106] | -7 | hSpCas9 | negative selection | 11918615 | 676376 | 676399 | 16 | - | 28162770 | MV411 | viability | GCTGTGCACCAGGCCAGTGAAGG | RHBDL1 | ENSG00000103269 | -0.24954156203224487 | [325] | [230] | -2 | hSpCas9 | negative selection | 11918616 | 676824 | 676847 | 16 | - | 28162770 | MV411 | viability | GACGGTAGAAGTACCAGCGGCGG | RHBDL1 | ENSG00000103269 | -0.567347576750317 | [145] | [82] | -4 | hSpCas9 | negative selection | 11918617 | 676997 | 677020 | 16 | - | 28162770 | MV411 | viability | GCAGCACCCACTTGTTGAGGCGG | RHBDL1 | ENSG00000103269 | 0.1973140713569388 | [614] | [593] | 1 | hSpCas9 | negative selection | 11918618 | 677077 | 677100 | 16 | - | 28162770 | MV411 | viability | GGTGAGGAAGCGCCAGGCGCGGG | RHBDL1 | ENSG00000103269 | -0.09359936705229144 | [56] | [44] | 0 | hSpCas9 | negative selection | 11918619 | 675808 | 675831 | 16 | + | 28162770 | MV411 | viability | GCTGCAGCTCATCCAGGAGCAGG | RHBDL1 | ENSG00000103269 | 1.3178268786741731 | [69] | [146] | 9 | hSpCas9 | negative selection | 11918620 | 676419 | 676442 | 16 | + | 28162770 | MV411 | viability | GGCCAAGCTGGACATGCTGGTGG | RHBDL1 | ENSG00000103269 | -0.49869531833284886 | [420] | [250] | -4 | hSpCas9 | negative selection | 11918621 | 676470 | 676493 | 16 | + | 28162770 | MV411 | viability | GGTCTGCTACCAGGAGCTGGTGG | RHBDL1 | ENSG00000103269 | -0.8650371784756372 | [79] | [36] | -5 | hSpCas9 | negative selection | 11918622 | 676703 | 676726 | 16 | + | 28162770 | MV411 | viability | GGGCCATTGCTAACGGACAGCGG | RHBDL1 | ENSG00000103269 | 1.734315051821742 | [70] | [198] | 9 | hSpCas9 | negative selection | 11918623 | 676350 | 676373 | 16 | + | 28162770 | MONOMAC1 | viability | GAACACAGGCTTCATCGGTGCGG | RHBDL1 | ENSG00000103269 | 0.43327933078132874 | [333] | [516] | 4 | hSpCas9 | negative selection | 12087980 | 676744 | 676767 | 16 | - | 28162770 | MONOMAC1 | viability | CCTAGGCCTGGCTCATCCAGCGG | RHBDL1 | ENSG00000103269 | -0.2576996289661778 | [169] | [162] | -2 | hSpCas9 | negative selection | 12087981 | 676376 | 676399 | 16 | - | 28162770 | MONOMAC1 | viability | GCTGTGCACCAGGCCAGTGAAGG | RHBDL1 | ENSG00000103269 | -0.33653626004765674 | [216] | [196] | -3 | hSpCas9 | negative selection | 12087982 | 676824 | 676847 | 16 | - | 28162770 | MONOMAC1 | viability | GACGGTAGAAGTACCAGCGGCGG | RHBDL1 | ENSG00000103269 | -0.7231056587271413 | [71] | [49] | -5 | hSpCas9 | negative selection | 12087983 | 676997 | 677020 | 16 | - | 28162770 | MONOMAC1 | viability | GCAGCACCCACTTGTTGAGGCGG | RHBDL1 | ENSG00000103269 | 0.677795532860493 | [360] | [661] | 6 | hSpCas9 | negative selection | 12087984 | 677077 | 677100 | 16 | - | 28162770 | MONOMAC1 | viability | GGTGAGGAAGCGCCAGGCGCGGG | RHBDL1 | ENSG00000103269 | -0.7376052284222567 | [31] | [21] | -6 | hSpCas9 | negative selection | 12087985 | 675808 | 675831 | 16 | + | 28162770 | MONOMAC1 | viability | GCTGCAGCTCATCCAGGAGCAGG | RHBDL1 | ENSG00000103269 | -0.6609839468193439 | [39] | [28] | -5 | hSpCas9 | negative selection | 12087986 | 676419 | 676442 | 16 | + | 28162770 | MONOMAC1 | viability | GGCCAAGCTGGACATGCTGGTGG | RHBDL1 | ENSG00000103269 | 0.17447327667836898 | [285] | [369] | 1 | hSpCas9 | negative selection | 12087987 | 676470 | 676493 | 16 | + | 28162770 | MONOMAC1 | viability | GGTCTGCTACCAGGAGCTGGTGG | RHBDL1 | ENSG00000103269 | -0.054078893217510915 | [47] | [52] | 0 | hSpCas9 | negative selection | 12087988 | 676703 | 676726 | 16 | + | 28162770 | MONOMAC1 | viability | GGGCCATTGCTAACGGACAGCGG | RHBDL1 | ENSG00000103269 | 0.22267713942876355 | [76] | [102] | 2 | hSpCas9 | negative selection | 12087989 | 676350 | 676373 | 16 | + | 28162770 | OCIAML2 | viability | GAACACAGGCTTCATCGGTGCGG | RHBDL1 | ENSG00000103269 | 0.20744207987047658 | [114] | [735] | 2 | hSpCas9 | negative selection | 12257346 | 676744 | 676767 | 16 | - | 28162770 | OCIAML2 | viability | CCTAGGCCTGGCTCATCCAGCGG | RHBDL1 | ENSG00000103269 | -0.22487341084020296 | [69] | [331] | -2 | hSpCas9 | negative selection | 12257347 | 676376 | 676399 | 16 | - | 28162770 | OCIAML2 | viability | GCTGTGCACCAGGCCAGTGAAGG | RHBDL1 | ENSG00000103269 | -1.952162736307912 | [73] | [105] | -8 | hSpCas9 | negative selection | 12257348 | 676824 | 676847 | 16 | - | 28162770 | OCIAML2 | viability | GACGGTAGAAGTACCAGCGGCGG | RHBDL1 | ENSG00000103269 | -0.7925579201295235 | [29] | [95] | -5 | hSpCas9 | negative selection | 12257349 | 676997 | 677020 | 16 | - | 28162770 | OCIAML2 | viability | GCAGCACCCACTTGTTGAGGCGG | RHBDL1 | ENSG00000103269 | -0.25375440887327905 | [130] | [608] | -2 | hSpCas9 | negative selection | 12257350 | 677077 | 677100 | 16 | - | 28162770 | OCIAML2 | viability | GGTGAGGAAGCGCCAGGCGCGGG | RHBDL1 | ENSG00000103269 | 0.24208822267736774 | [8] | [58] | 2 | hSpCas9 | negative selection | 12257351 | 675808 | 675831 | 16 | + | 28162770 | OCIAML2 | viability | GCTGCAGCTCATCCAGGAGCAGG | RHBDL1 | ENSG00000103269 | -0.06034585593395181 | [18] | [100] | 0 | hSpCas9 | negative selection | 12257352 | 676419 | 676442 | 16 | + | 28162770 | OCIAML2 | viability | GGCCAAGCTGGACATGCTGGTGG | RHBDL1 | ENSG00000103269 | 0.13531770060833082 | [90] | [553] | 1 | hSpCas9 | negative selection | 12257353 | 676470 | 676493 | 16 | + | 28162770 | OCIAML2 | viability | GGTCTGCTACCAGGAGCTGGTGG | RHBDL1 | ENSG00000103269 | -0.47062982524216146 | [13] | [55] | -4 | hSpCas9 | negative selection | 12257354 | 676703 | 676726 | 16 | + | 28162770 | OCIAML2 | viability | GGGCCATTGCTAACGGACAGCGG | RHBDL1 | ENSG00000103269 | -0.19450541996792356 | [31] | [154] | -2 | hSpCas9 | negative selection | 12257355 | 676350 | 676373 | 16 | + | 28162770 | OCIAML3 | viability | GAACACAGGCTTCATCGGTGCGG | RHBDL1 | ENSG00000103269 | 0.5991646420972914 | [170] | [781] | 5 | hSpCas9 | negative selection | 12426712 | 676744 | 676767 | 16 | - | 28162770 | OCIAML3 | viability | CCTAGGCCTGGCTCATCCAGCGG | RHBDL1 | ENSG00000103269 | -0.7009228442406753 | [90] | [168] | -5 | hSpCas9 | negative selection | 12426713 | 676376 | 676399 | 16 | - | 28162770 | OCIAML3 | viability | GCTGTGCACCAGGCCAGTGAAGG | RHBDL1 | ENSG00000103269 | -0.7408490286534343 | [92] | [167] | -5 | hSpCas9 | negative selection | 12426714 | 676824 | 676847 | 16 | - | 28162770 | OCIAML3 | viability | GACGGTAGAAGTACCAGCGGCGG | RHBDL1 | ENSG00000103269 | -0.38964914181797705 | [22] | [52] | -3 | hSpCas9 | negative selection | 12426715 | 676997 | 677020 | 16 | - | 28162770 | OCIAML3 | viability | GCAGCACCCACTTGTTGAGGCGG | RHBDL1 | ENSG00000103269 | 0.41460548998054514 | [166] | [671] | 4 | hSpCas9 | negative selection | 12426716 | 677077 | 677100 | 16 | - | 28162770 | OCIAML3 | viability | GGTGAGGAAGCGCCAGGCGCGGG | RHBDL1 | ENSG00000103269 | -1.0704456842671504 | [15] | [22] | -6 | hSpCas9 | negative selection | 12426717 | 675808 | 675831 | 16 | + | 28162770 | OCIAML3 | viability | GCTGCAGCTCATCCAGGAGCAGG | RHBDL1 | ENSG00000103269 | 1.005030045608716 | [16] | [102] | 8 | hSpCas9 | negative selection | 12426718 | 676419 | 676442 | 16 | + | 28162770 | OCIAML3 | viability | GGCCAAGCTGGACATGCTGGTGG | RHBDL1 | ENSG00000103269 | 0.22396839749001352 | [115] | [408] | 2 | hSpCas9 | negative selection | 12426719 | 676470 | 676493 | 16 | + | 28162770 | OCIAML3 | viability | GGTCTGCTACCAGGAGCTGGTGG | RHBDL1 | ENSG00000103269 | -1.6814704815745023 | [16] | [15] | -8 | hSpCas9 | negative selection | 12426720 | 676703 | 676726 | 16 | + | 28162770 | OCIAML3 | viability | GGGCCATTGCTAACGGACAGCGG | RHBDL1 | ENSG00000103269 | 1.0063849009665993 | [30] | [187] | 8 | hSpCas9 | negative selection | 12426721 |