Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:6009
• Symbol:RHEB
• Description:Ras homolog, mTORC1 binding

DataSource: http://genomecrispr.dkfz.de/#!/results/RHEB

Export (tab separated) Export to Excel

Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
151519448	151519471	7	+	26472758	Jiyoye	viability	CCGGCCACTCACCCACAGACCGG	RHEB	ENSG00000106615	-1.429325886211247	[199]	[55]	-7	hSpCas9	negative selection	136724
151470610	151470633	7	-	26472758	Jiyoye	viability	GGAAAGCTTTGGCAGAATCTTGG	RHEB	ENSG00000106615	-0.14607825948794462	[134]	[91]	-1	hSpCas9	negative selection	136725
151519491	151519514	7	-	26472758	Jiyoye	viability	AGATGCCGCAGTCCAAGTCCCGG	RHEB	ENSG00000106615	-0.9072386597241823	[382]	[153]	-6	hSpCas9	negative selection	136726
151467202	151467225	7	-	26472758	Jiyoye	viability	TTTCTCTTTTCAGACTGCTGTGG	RHEB	ENSG00000106615	0.3892534735086111	[161]	[159]	3	hSpCas9	negative selection	136727
151467144	151467167	7	-	26472758	Jiyoye	viability	ATGGACGGGGCAGCTTCACAAGG	RHEB	ENSG00000106615	-0.8613134544200284	[105]	[43]	-6	hSpCas9	negative selection	136728
151471557	151471580	7	-	26472758	Jiyoye	viability	GCAAATTGTTGGATATGGTGGGG	RHEB	ENSG00000106615	-1.272944352255623	[140]	[43]	-7	hSpCas9	negative selection	136729
151470632	151470655	7	-	26472758	Jiyoye	viability	AGGGTGATCAGTTATGAAGAAGG	RHEB	ENSG00000106615	-0.4835955487393683	[88]	[47]	-3	hSpCas9	negative selection	136730
151471393	151471416	7	-	26472758	Jiyoye	viability	AGAAAGACCTGCATATGGAAAGG	RHEB	ENSG00000106615	-2.8716839914896033	[164]	[16]	-9	hSpCas9	negative selection	136731
151490944	151490967	7	+	26472758	Jiyoye	viability	GTTTTCTATGGTTGGATCGTAGG	RHEB	ENSG00000106615	-1.2631786104459275	[260]	[81]	-7	hSpCas9	negative selection	136732
151519460	151519483	7	-	26472758	Jiyoye	viability	GATCCTGGGCTACCGGTCTGTGG	RHEB	ENSG00000106615	-2.2005071957153666	[255]	[41]	-8	hSpCas9	negative selection	136733
151519448	151519471	7	+	26472758	KBM7	viability	CCGGCCACTCACCCACAGACCGG	RHEB	ENSG00000106615	-1.164538542221305	[899,777]	[89,251]	-7	hSpCas9	negative selection	327842
151470610	151470633	7	-	26472758	KBM7	viability	GGAAAGCTTTGGCAGAATCTTGG	RHEB	ENSG00000106615	-0.4085347919288532	[517,647]	[164,249]	-4	hSpCas9	negative selection	327843
151519491	151519514	7	-	26472758	KBM7	viability	AGATGCCGCAGTCCAAGTCCCGG	RHEB	ENSG00000106615	-1.6293509315796633	[1730,1403]	[201,267]	-8	hSpCas9	negative selection	327844
151467202	151467225	7	-	26472758	KBM7	viability	TTTCTCTTTTCAGACTGCTGTGG	RHEB	ENSG00000106615	0.6066614694712749	[608,482]	[355,416]	6	hSpCas9	negative selection	327845
151467144	151467167	7	-	26472758	KBM7	viability	ATGGACGGGGCAGCTTCACAAGG	RHEB	ENSG00000106615	-0.3527258980399993	[777,374]	[229,183]	-3	hSpCas9	negative selection	327846
151471557	151471580	7	-	26472758	KBM7	viability	GCAAATTGTTGGATATGGTGGGG	RHEB	ENSG00000106615	-1.4879277664378376	[719,458]	[76,114]	-8	hSpCas9	negative selection	327847
151470632	151470655	7	-	26472758	KBM7	viability	AGGGTGATCAGTTATGAAGAAGG	RHEB	ENSG00000106615	-0.46108876601763243	[579,398]	[129,195]	-4	hSpCas9	negative selection	327848
151471393	151471416	7	-	26472758	KBM7	viability	AGAAAGACCTGCATATGGAAAGG	RHEB	ENSG00000106615	-1.61340029942088	[507,532]	[116,47]	-8	hSpCas9	negative selection	327849
151490944	151490967	7	+	26472758	KBM7	viability	GTTTTCTATGGTTGGATCGTAGG	RHEB	ENSG00000106615	-0.7548604275708616	[1278,1380]	[357,387]	-6	hSpCas9	negative selection	327850
151519460	151519483	7	-	26472758	KBM7	viability	GATCCTGGGCTACCGGTCTGTGG	RHEB	ENSG00000106615	-0.8912745756449756	[707,569]	[132,185]	-6	hSpCas9	negative selection	327851
151519448	151519471	7	+	26472758	Raji	viability	CCGGCCACTCACCCACAGACCGG	RHEB	ENSG00000106615	-2.9075668060923725	[484]	[14]	-9	hSpCas9	negative selection	518960
151470610	151470633	7	-	26472758	Raji	viability	GGAAAGCTTTGGCAGAATCTTGG	RHEB	ENSG00000106615	0.5507497577109376	[352]	[119]	5	hSpCas9	negative selection	518961
151519491	151519514	7	-	26472758	Raji	viability	AGATGCCGCAGTCCAAGTCCCGG	RHEB	ENSG00000106615	-1.3850523503160055	[618]	[54]	-7	hSpCas9	negative selection	518962
151467202	151467225	7	-	26472758	Raji	viability	TTTCTCTTTTCAGACTGCTGTGG	RHEB	ENSG00000106615	0.21927641544449666	[247]	[66]	2	hSpCas9	negative selection	518963
151467144	151467167	7	-	26472758	Raji	viability	ATGGACGGGGCAGCTTCACAAGG	RHEB	ENSG00000106615	0.13496936704549903	[258]	[65]	1	hSpCas9	negative selection	518964
151471557	151471580	7	-	26472758	Raji	viability	GCAAATTGTTGGATATGGTGGGG	RHEB	ENSG00000106615	-3.725506478791142	[341]	[5]	-9	hSpCas9	negative selection	518965
151470632	151470655	7	-	26472758	Raji	viability	AGGGTGATCAGTTATGAAGAAGG	RHEB	ENSG00000106615	-1.0001449289308455	[180]	[20]	-6	hSpCas9	negative selection	518966
151471393	151471416	7	-	26472758	Raji	viability	AGAAAGACCTGCATATGGAAAGG	RHEB	ENSG00000106615	-1.5330740779392602	[211]	[16]	-8	hSpCas9	negative selection	518967
151490944	151490967	7	+	26472758	Raji	viability	GTTTTCTATGGTTGGATCGTAGG	RHEB	ENSG00000106615	-2.7708067479816108	[646]	[21]	-9	hSpCas9	negative selection	518968
151519460	151519483	7	-	26472758	Raji	viability	GATCCTGGGCTACCGGTCTGTGG	RHEB	ENSG00000106615	-2.4614592999842797	[355]	[14]	-9	hSpCas9	negative selection	518969
151519448	151519471	7	+	26472758	K562	viability	CCGGCCACTCACCCACAGACCGG	RHEB	ENSG00000106615	-1.173338272965989	[707]	[264]	-6	hSpCas9	negative selection	710078
151470610	151470633	7	-	26472758	K562	viability	GGAAAGCTTTGGCAGAATCTTGG	RHEB	ENSG00000106615	-1.1740334360251614	[563]	[210]	-6	hSpCas9	negative selection	710079
151519491	151519514	7	-	26472758	K562	viability	AGATGCCGCAGTCCAAGTCCCGG	RHEB	ENSG00000106615	-0.987178855670632	[1152]	[490]	-5	hSpCas9	negative selection	710080
151467202	151467225	7	-	26472758	K562	viability	TTTCTCTTTTCAGACTGCTGTGG	RHEB	ENSG00000106615	0.6908691795767521	[476]	[649]	5	hSpCas9	negative selection	710081
151467144	151467167	7	-	26472758	K562	viability	ATGGACGGGGCAGCTTCACAAGG	RHEB	ENSG00000106615	-2.1505728294106388	[404]	[76]	-7	hSpCas9	negative selection	710082
151471557	151471580	7	-	26472758	K562	viability	GCAAATTGTTGGATATGGTGGGG	RHEB	ENSG00000106615	-2.153265204862129	[605]	[114]	-7	hSpCas9	negative selection	710083
151470632	151470655	7	-	26472758	K562	viability	AGGGTGATCAGTTATGAAGAAGG	RHEB	ENSG00000106615	-1.7902274151404445	[294]	[71]	-7	hSpCas9	negative selection	710084
151471393	151471416	7	-	26472758	K562	viability	AGAAAGACCTGCATATGGAAAGG	RHEB	ENSG00000106615	-3.037616640097403	[427]	[43]	-8	hSpCas9	negative selection	710085
151490944	151490967	7	+	26472758	K562	viability	GTTTTCTATGGTTGGATCGTAGG	RHEB	ENSG00000106615	-1.229803150781978	[1102]	[396]	-6	hSpCas9	negative selection	710086
151519460	151519483	7	-	26472758	K562	viability	GATCCTGGGCTACCGGTCTGTGG	RHEB	ENSG00000106615	-1.295367634502356	[502]	[172]	-6	hSpCas9	negative selection	710087
151520040	151520063	7	-	25494202	A375	resistance to PLX-4720 (puromycin)	GAGGTGTATTTTTAGCTCCCGGG	RHEB	ENSG00000106615	-2.0702175508296863	[536,92]	[26,3]	-9	dCas9-VP64	positive selection	2438342
151520066	151520089	7	+	25494202	A375	resistance to PLX-4720 (puromycin)	GCTACCGCGCTGTTGGGCGCCGG	RHEB	ENSG00000106615	3.0642703808760507	[0,12]	[6,18]	8	dCas9-VP64	positive selection	2438343
151520085	151520108	7	-	25494202	A375	resistance to PLX-4720 (puromycin)	TTGAAGCCTTCAAACCTAGCCGG	RHEB	ENSG00000106615	-1.634534064258511	[379,740]	[9,70]	-8	dCas9-VP64	positive selection	2438344
151520040	151520063	7	-	25494202	A375	resistance to PLX-4720 (zeocin)	GAGGTGTATTTTTAGCTCCCGGG	RHEB	ENSG00000106615	-0.36174578854202655	[223,145]	[68,25]	-4	dCas9-VP64	positive selection	2533597
151520066	151520089	7	+	25494202	A375	resistance to PLX-4720 (zeocin)	GCTACCGCGCTGTTGGGCGCCGG	RHEB	ENSG00000106615	-1.604516898241524	[129,62]	[9,8]	-9	dCas9-VP64	positive selection	2533598
151520085	151520108	7	-	25494202	A375	resistance to PLX-4720 (zeocin)	TTGAAGCCTTCAAACCTAGCCGG	RHEB	ENSG00000106615	1.94991374625211	[151,197]	[417,35]	8	dCas9-VP64	positive selection	2533599
151498126	151498149	7	-	27260157	DLD1	viability	GAGTGGTGTTATAGTTCTGCAGG	RHEB	ENSG00000106615	-0.574250940351685	[]	[]	-5	hSpCas9	negative selection	2574011
151519512	151519535	7	+	27260157	DLD1	viability	CTTGGCGGCCTCCTCAGCCCCGG	RHEB	ENSG00000106615	-2.60157449318631	[]	[]	-9	hSpCas9	negative selection	2575298
151498088	151498111	7	-	27260157	DLD1	viability	CCCATGGGCACATTTAATTTAGG	RHEB	ENSG00000106615	0.173015860071167	[]	[]	3	hSpCas9	negative selection	2579008
151519494	151519517	7	+	27260157	DLD1	viability	GGACTTGGACTGCGGCATCTTGG	RHEB	ENSG00000106615	-1.58712941969272	[]	[]	-8	hSpCas9	negative selection	2581920
151498089	151498112	7	+	27260157	DLD1	viability	CTAAATTAAATGTGCCCATGGGG	RHEB	ENSG00000106615	0.147323996632278	[]	[]	3	hSpCas9	negative selection	2582849
151498148	151498171	7	+	27260157	DLD1	viability	CACAACAGGTGCGTAGGTCCTGG	RHEB	ENSG00000106615	-0.0337930988369131	[]	[]	0	hSpCas9	negative selection	2586070
151498117	151498140	7	-	27260157	DLD1	viability	TATAGTTCTGCAGGGCGCACAGG	RHEB	ENSG00000106615	-0.412726753756123	[]	[]	-3	hSpCas9	negative selection	2586279
151498142	151498165	7	+	27260157	DLD1	viability	ACCACTCACAACAGGTGCGTAGG	RHEB	ENSG00000106615	0.363953370104298	[]	[]	4	hSpCas9	negative selection	2607589
151471425	151471448	7	-	27260157	DLD1	viability	AAATAGAATACCTATTATGTTGG	RHEB	ENSG00000106615	-2.38322502020524	[]	[]	-9	hSpCas9	negative selection	2609796
151498134	151498157	7	+	27260157	DLD1	viability	ACTATAACACCACTCACAACAGG	RHEB	ENSG00000106615	0.860534462509939	[]	[]	9	hSpCas9	negative selection	2610107
151519457	151519480	7	+	27260157	DLD1	viability	CACCCACAGACCGGTAGCCCAGG	RHEB	ENSG00000106615	-0.646460011661525	[]	[]	-5	hSpCas9	negative selection	2614582
151498125	151498148	7	-	27260157	DLD1	viability	AGTGGTGTTATAGTTCTGCAGGG	RHEB	ENSG00000106615	-0.116335536602693	[]	[]	-1	hSpCas9	negative selection	2616987
151498155	151498178	7	+	27260157	DLD1	viability	GGTGCGTAGGTCCTGGCTTGAGG	RHEB	ENSG00000106615	-0.387437134074049	[]	[]	-3	hSpCas9	negative selection	2621483
151519497	151519520	7	+	27260157	DLD1	viability	CTTGGACTGCGGCATCTTGGCGG	RHEB	ENSG00000106615	-0.4719577261274	[]	[]	-4	hSpCas9	negative selection	2621914
151498104	151498127	7	-	27260157	DLD1	viability	GGCGCACAGGTGCATCCCCATGG	RHEB	ENSG00000106615	0.351910106013332	[]	[]	4	hSpCas9	negative selection	2643204
151498143	151498166	7	-	27260157	DLD1	viability	ACCTACGCACCTGTTGTGAGTGG	RHEB	ENSG00000106615	0.313555467945947	[]	[]	4	hSpCas9	negative selection	2644232
151498088	151498111	7	+	27260157	DLD1	viability	CCTAAATTAAATGTGCCCATGGG	RHEB	ENSG00000106615	0.716469099278995	[]	[]	8	hSpCas9	negative selection	2645236
151498103	151498126	7	-	27260157	DLD1	viability	GCGCACAGGTGCATCCCCATGGG	RHEB	ENSG00000106615	0.110905858955839	[]	[]	3	hSpCas9	negative selection	2647206
151498126	151498149	7	-	27260157	HT1080	viability	GAGTGGTGTTATAGTTCTGCAGG	RHEB	ENSG00000106615	0.542358679035041	[]	[]	5	hSpCas9	negative selection	2650141
151519512	151519535	7	+	27260157	HT1080	viability	CTTGGCGGCCTCCTCAGCCCCGG	RHEB	ENSG00000106615	-0.877043018234621	[]	[]	-8	hSpCas9	negative selection	2651428
151498088	151498111	7	-	27260157	HT1080	viability	CCCATGGGCACATTTAATTTAGG	RHEB	ENSG00000106615	0.35949854931351	[]	[]	3	hSpCas9	negative selection	2655138
151519494	151519517	7	+	27260157	HT1080	viability	GGACTTGGACTGCGGCATCTTGG	RHEB	ENSG00000106615	-2.17821300633526	[]	[]	-9	hSpCas9	negative selection	2658050
151498089	151498112	7	+	27260157	HT1080	viability	CTAAATTAAATGTGCCCATGGGG	RHEB	ENSG00000106615	0.696908086110217	[]	[]	6	hSpCas9	negative selection	2658979
151498148	151498171	7	+	27260157	HT1080	viability	CACAACAGGTGCGTAGGTCCTGG	RHEB	ENSG00000106615	0.624941289148211	[]	[]	5	hSpCas9	negative selection	2662200
151498117	151498140	7	-	27260157	HT1080	viability	TATAGTTCTGCAGGGCGCACAGG	RHEB	ENSG00000106615	-0.488292766470837	[]	[]	-7	hSpCas9	negative selection	2662409
151498142	151498165	7	+	27260157	HT1080	viability	ACCACTCACAACAGGTGCGTAGG	RHEB	ENSG00000106615	0.445010652408714	[]	[]	4	hSpCas9	negative selection	2683719
151471425	151471448	7	-	27260157	HT1080	viability	AAATAGAATACCTATTATGTTGG	RHEB	ENSG00000106615	-1.58750496152358	[]	[]	-9	hSpCas9	negative selection	2685926
151498134	151498157	7	+	27260157	HT1080	viability	ACTATAACACCACTCACAACAGG	RHEB	ENSG00000106615	0.888352476933573	[]	[]	7	hSpCas9	negative selection	2686237
151519457	151519480	7	+	27260157	HT1080	viability	CACCCACAGACCGGTAGCCCAGG	RHEB	ENSG00000106615	-0.719379356435582	[]	[]	-8	hSpCas9	negative selection	2690712
151498125	151498148	7	-	27260157	HT1080	viability	AGTGGTGTTATAGTTCTGCAGGG	RHEB	ENSG00000106615	-0.235309101671723	[]	[]	0	hSpCas9	negative selection	2693117
151498155	151498178	7	+	27260157	HT1080	viability	GGTGCGTAGGTCCTGGCTTGAGG	RHEB	ENSG00000106615	-1.24304893961113	[]	[]	-9	hSpCas9	negative selection	2697613
151519497	151519520	7	+	27260157	HT1080	viability	CTTGGACTGCGGCATCTTGGCGG	RHEB	ENSG00000106615	-1.4693893039129	[]	[]	-9	hSpCas9	negative selection	2698044
151498104	151498127	7	-	27260157	HT1080	viability	GGCGCACAGGTGCATCCCCATGG	RHEB	ENSG00000106615	-0.583952281449887	[]	[]	-7	hSpCas9	negative selection	2719334
151498143	151498166	7	-	27260157	HT1080	viability	ACCTACGCACCTGTTGTGAGTGG	RHEB	ENSG00000106615	0.233135285801431	[]	[]	2	hSpCas9	negative selection	2720362
151498088	151498111	7	+	27260157	HT1080	viability	CCTAAATTAAATGTGCCCATGGG	RHEB	ENSG00000106615	0.00721710243300579	[]	[]	0	hSpCas9	negative selection	2721366
151498103	151498126	7	-	27260157	HT1080	viability	GCGCACAGGTGCATCCCCATGGG	RHEB	ENSG00000106615	-0.33448512142095	[]	[]	-7	hSpCas9	negative selection	2723336
151498126	151498149	7	-	27260157	MKN45	viability	GAGTGGTGTTATAGTTCTGCAGG	RHEB	ENSG00000106615	-2.13104722916133	[]	[]	-9	hSpCas9	negative selection	2726271
151519512	151519535	7	+	27260157	MKN45	viability	CTTGGCGGCCTCCTCAGCCCCGG	RHEB	ENSG00000106615	-2.48712830540058	[]	[]	-9	hSpCas9	negative selection	2727558
151498088	151498111	7	-	27260157	MKN45	viability	CCCATGGGCACATTTAATTTAGG	RHEB	ENSG00000106615	0.535287987235514	[]	[]	6	hSpCas9	negative selection	2731268
151519494	151519517	7	+	27260157	MKN45	viability	GGACTTGGACTGCGGCATCTTGG	RHEB	ENSG00000106615	-1.28034407075748	[]	[]	-8	hSpCas9	negative selection	2734180
151498089	151498112	7	+	27260157	MKN45	viability	CTAAATTAAATGTGCCCATGGGG	RHEB	ENSG00000106615	-0.508818379790485	[]	[]	-6	hSpCas9	negative selection	2735109
151498148	151498171	7	+	27260157	MKN45	viability	CACAACAGGTGCGTAGGTCCTGG	RHEB	ENSG00000106615	-0.506070929720259	[]	[]	-6	hSpCas9	negative selection	2738330
151498117	151498140	7	-	27260157	MKN45	viability	TATAGTTCTGCAGGGCGCACAGG	RHEB	ENSG00000106615	0.131682740216886	[]	[]	4	hSpCas9	negative selection	2738539
151498142	151498165	7	+	27260157	MKN45	viability	ACCACTCACAACAGGTGCGTAGG	RHEB	ENSG00000106615	-0.00462719116080687	[]	[]	0	hSpCas9	negative selection	2759849
151471425	151471448	7	-	27260157	MKN45	viability	AAATAGAATACCTATTATGTTGG	RHEB	ENSG00000106615	-1.94744927229177	[]	[]	-9	hSpCas9	negative selection	2762056
151498134	151498157	7	+	27260157	MKN45	viability	ACTATAACACCACTCACAACAGG	RHEB	ENSG00000106615	0.927890279206074	[]	[]	8	hSpCas9	negative selection	2762367
151519457	151519480	7	+	27260157	MKN45	viability	CACCCACAGACCGGTAGCCCAGG	RHEB	ENSG00000106615	-0.844063827965055	[]	[]	-7	hSpCas9	negative selection	2766842
151498125	151498148	7	-	27260157	MKN45	viability	AGTGGTGTTATAGTTCTGCAGGG	RHEB	ENSG00000106615	0.89295071888603	[]	[]	8	hSpCas9	negative selection	2769247
151498155	151498178	7	+	27260157	MKN45	viability	GGTGCGTAGGTCCTGGCTTGAGG	RHEB	ENSG00000106615	-1.05850438202176	[]	[]	-8	hSpCas9	negative selection	2773743
151519497	151519520	7	+	27260157	MKN45	viability	CTTGGACTGCGGCATCTTGGCGG	RHEB	ENSG00000106615	-1.56844485561523	[]	[]	-9	hSpCas9	negative selection	2774174
151498104	151498127	7	-	27260157	MKN45	viability	GGCGCACAGGTGCATCCCCATGG	RHEB	ENSG00000106615	-0.118782716702472	[]	[]	0	hSpCas9	negative selection	2795464
151498143	151498166	7	-	27260157	MKN45	viability	ACCTACGCACCTGTTGTGAGTGG	RHEB	ENSG00000106615	0.183361600055277	[]	[]	5	hSpCas9	negative selection	2796492
151498088	151498111	7	+	27260157	MKN45	viability	CCTAAATTAAATGTGCCCATGGG	RHEB	ENSG00000106615	-0.756300456327546	[]	[]	-7	hSpCas9	negative selection	2797496
151498103	151498126	7	-	27260157	MKN45	viability	GCGCACAGGTGCATCCCCATGGG	RHEB	ENSG00000106615	-0.194010181765326	[]	[]	0	hSpCas9	negative selection	2799466
151498126	151498149	7	-	27260157	RKO	viability	GAGTGGTGTTATAGTTCTGCAGG	RHEB	ENSG00000106615	-1.32195710980367	[]	[]	-8	hSpCas9	negative selection	2802401
151519512	151519535	7	+	27260157	RKO	viability	CTTGGCGGCCTCCTCAGCCCCGG	RHEB	ENSG00000106615	-3.80494446843882	[]	[]	-9	hSpCas9	negative selection	2803688
151498088	151498111	7	-	27260157	RKO	viability	CCCATGGGCACATTTAATTTAGG	RHEB	ENSG00000106615	0.652959158822251	[]	[]	3	hSpCas9	negative selection	2807398
151519494	151519517	7	+	27260157	RKO	viability	GGACTTGGACTGCGGCATCTTGG	RHEB	ENSG00000106615	-1.38039436807154	[]	[]	-8	hSpCas9	negative selection	2810310
151498089	151498112	7	+	27260157	RKO	viability	CTAAATTAAATGTGCCCATGGGG	RHEB	ENSG00000106615	-0.333568101539085	[]	[]	-6	hSpCas9	negative selection	2811239
151498148	151498171	7	+	27260157	RKO	viability	CACAACAGGTGCGTAGGTCCTGG	RHEB	ENSG00000106615	-0.488787836718477	[]	[]	-6	hSpCas9	negative selection	2814460
151498117	151498140	7	-	27260157	RKO	viability	TATAGTTCTGCAGGGCGCACAGG	RHEB	ENSG00000106615	-0.149732927849226	[]	[]	0	hSpCas9	negative selection	2814669
151498142	151498165	7	+	27260157	RKO	viability	ACCACTCACAACAGGTGCGTAGG	RHEB	ENSG00000106615	-0.229621166968357	[]	[]	-1	hSpCas9	negative selection	2835979
151471425	151471448	7	-	27260157	RKO	viability	AAATAGAATACCTATTATGTTGG	RHEB	ENSG00000106615	-2.95776498113949	[]	[]	-9	hSpCas9	negative selection	2838186
151498134	151498157	7	+	27260157	RKO	viability	ACTATAACACCACTCACAACAGG	RHEB	ENSG00000106615	0.0548542193451981	[]	[]	0	hSpCas9	negative selection	2838497
151519457	151519480	7	+	27260157	RKO	viability	CACCCACAGACCGGTAGCCCAGG	RHEB	ENSG00000106615	-0.843716928542515	[]	[]	-7	hSpCas9	negative selection	2842972
151498125	151498148	7	-	27260157	RKO	viability	AGTGGTGTTATAGTTCTGCAGGG	RHEB	ENSG00000106615	-0.174135571565164	[]	[]	-1	hSpCas9	negative selection	2845377
151498155	151498178	7	+	27260157	RKO	viability	GGTGCGTAGGTCCTGGCTTGAGG	RHEB	ENSG00000106615	-0.363420531052558	[]	[]	-6	hSpCas9	negative selection	2849873
151519497	151519520	7	+	27260157	RKO	viability	CTTGGACTGCGGCATCTTGGCGG	RHEB	ENSG00000106615	-0.597184018926871	[]	[]	-7	hSpCas9	negative selection	2850304
151498104	151498127	7	-	27260157	RKO	viability	GGCGCACAGGTGCATCCCCATGG	RHEB	ENSG00000106615	0.317852776441872	[]	[]	1	hSpCas9	negative selection	2871594
151498143	151498166	7	-	27260157	RKO	viability	ACCTACGCACCTGTTGTGAGTGG	RHEB	ENSG00000106615	0.608325603693723	[]	[]	3	hSpCas9	negative selection	2872622
151498088	151498111	7	+	27260157	RKO	viability	CCTAAATTAAATGTGCCCATGGG	RHEB	ENSG00000106615	-0.218911808772905	[]	[]	-1	hSpCas9	negative selection	2873626
151498103	151498126	7	-	27260157	RKO	viability	GCGCACAGGTGCATCCCCATGGG	RHEB	ENSG00000106615	-0.694478232809883	[]	[]	-7	hSpCas9	negative selection	2875596
151498126	151498149	7	-	27260157	SF268	viability	GAGTGGTGTTATAGTTCTGCAGG	RHEB	ENSG00000106615	-0.41639354757029	[]	[]	-3	hSpCas9	negative selection	2878531
151519512	151519535	7	+	27260157	SF268	viability	CTTGGCGGCCTCCTCAGCCCCGG	RHEB	ENSG00000106615	-1.15408381624723	[]	[]	-7	hSpCas9	negative selection	2879818
151498088	151498111	7	-	27260157	SF268	viability	CCCATGGGCACATTTAATTTAGG	RHEB	ENSG00000106615	0.675946976230367	[]	[]	8	hSpCas9	negative selection	2883528
151519494	151519517	7	+	27260157	SF268	viability	GGACTTGGACTGCGGCATCTTGG	RHEB	ENSG00000106615	-0.282778170465525	[]	[]	-2	hSpCas9	negative selection	2886440
151498089	151498112	7	+	27260157	SF268	viability	CTAAATTAAATGTGCCCATGGGG	RHEB	ENSG00000106615	-0.149624547433813	[]	[]	-1	hSpCas9	negative selection	2887369
151498148	151498171	7	+	27260157	SF268	viability	CACAACAGGTGCGTAGGTCCTGG	RHEB	ENSG00000106615	0.58602310536918	[]	[]	8	hSpCas9	negative selection	2890590
151498117	151498140	7	-	27260157	SF268	viability	TATAGTTCTGCAGGGCGCACAGG	RHEB	ENSG00000106615	0.234813692067546	[]	[]	3	hSpCas9	negative selection	2890799
151498142	151498165	7	+	27260157	SF268	viability	ACCACTCACAACAGGTGCGTAGG	RHEB	ENSG00000106615	0.589680976119939	[]	[]	8	hSpCas9	negative selection	2912109
151471425	151471448	7	-	27260157	SF268	viability	AAATAGAATACCTATTATGTTGG	RHEB	ENSG00000106615	-0.934230801826856	[]	[]	-6	hSpCas9	negative selection	2914316
151498134	151498157	7	+	27260157	SF268	viability	ACTATAACACCACTCACAACAGG	RHEB	ENSG00000106615	-0.0961855544526926	[]	[]	0	hSpCas9	negative selection	2914627
151519457	151519480	7	+	27260157	SF268	viability	CACCCACAGACCGGTAGCCCAGG	RHEB	ENSG00000106615	-0.0415700603520192	[]	[]	0	hSpCas9	negative selection	2919102
151498125	151498148	7	-	27260157	SF268	viability	AGTGGTGTTATAGTTCTGCAGGG	RHEB	ENSG00000106615	0.736233210623423	[]	[]	8	hSpCas9	negative selection	2921507
151498155	151498178	7	+	27260157	SF268	viability	GGTGCGTAGGTCCTGGCTTGAGG	RHEB	ENSG00000106615	-1.3319376321048	[]	[]	-7	hSpCas9	negative selection	2926003
151519497	151519520	7	+	27260157	SF268	viability	CTTGGACTGCGGCATCTTGGCGG	RHEB	ENSG00000106615	-0.206074654205791	[]	[]	-2	hSpCas9	negative selection	2926434
151498104	151498127	7	-	27260157	SF268	viability	GGCGCACAGGTGCATCCCCATGG	RHEB	ENSG00000106615	0.0143102037113741	[]	[]	0	hSpCas9	negative selection	2947724
151498143	151498166	7	-	27260157	SF268	viability	ACCTACGCACCTGTTGTGAGTGG	RHEB	ENSG00000106615	0.582041548343126	[]	[]	8	hSpCas9	negative selection	2948752
151498088	151498111	7	+	27260157	SF268	viability	CCTAAATTAAATGTGCCCATGGG	RHEB	ENSG00000106615	0.32525109809274	[]	[]	4	hSpCas9	negative selection	2949756
151498103	151498126	7	-	27260157	SF268	viability	GCGCACAGGTGCATCCCCATGGG	RHEB	ENSG00000106615	0.190160390093471	[]	[]	0	hSpCas9	negative selection	2951726
151477376	151477399	7	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	ATATCTATGGAGTATGTCTGAGG	RHEB	ENSG00000106615	-0.39821428814564513	[3,3]	[2,1]	-5	hSpCas9	positive selection	3016752
151484723	151484746	7	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CCAGAGGTCACTTACTTGCCCGG	RHEB	ENSG00000106615	-0.9014036167591337	[2,2]	[1,0]	-8	hSpCas9	positive selection	3016753
151477376	151477399	7	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	ATATCTATGGAGTATGTCTGAGG	RHEB	ENSG00000106615	-0.3177255118012305	[3,3]	[2,0]	-5	hSpCas9	positive selection	3084610
151484723	151484746	7	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CCAGAGGTCACTTACTTGCCCGG	RHEB	ENSG00000106615	-0.8286819574229718	[2,2]	[1,0]	-9	hSpCas9	positive selection	3084611
151490932	151490955		+	24336571	A375	resistance to PLX after 7 days	ACAATACTTACTGTTTTCTATGG	RHEB	ENSG00000106615	-0.0776506583419374	[5,5]	[5,5]	-2	hSpCas9	positive selection	3140855
151484741	151484764		-	24336571	A375	resistance to PLX after 7 days	CTTCAACTTGTAGACACAGCCGG	RHEB	ENSG00000106615	0.13737507427432616	[9,9]	[10,11]	4	hSpCas9	positive selection	3140856
151490932	151490955		+	24336571	A375	resistance to PLX after 14 days	ACAATACTTACTGTTTTCTATGG	RHEB	ENSG00000106615	0.5097624849164168	[7,3]	[2,3]	5	hSpCas9	positive selection	3198648
151484741	151484764		-	24336571	A375	resistance to PLX after 14 days	CTTCAACTTGTAGACACAGCCGG	RHEB	ENSG00000106615	-0.06278262058524708	[8,7]	[3,3]	0	hSpCas9	positive selection	3198649
151490932	151490955		+	24336571	A375	viability after 7 days	ACAATACTTACTGTTTTCTATGG	RHEB	ENSG00000106615	0.07514827570130089	[5]	[5,5]	1	hSpCas9	negative selection	3256441
151484741	151484764		-	24336571	A375	viability after 7 days	CTTCAACTTGTAGACACAGCCGG	RHEB	ENSG00000106615	-0.5026873453985051	[15]	[9,9]	-6	hSpCas9	negative selection	3256442
151490932	151490955		+	24336571	A375	viability after 14 days	ACAATACTTACTGTTTTCTATGG	RHEB	ENSG00000106615	-0.0677149783329809	[5]	[7,3]	0	hSpCas9	negative selection	3314234
151484741	151484764		-	24336571	A375	viability after 14 days	CTTCAACTTGTAGACACAGCCGG	RHEB	ENSG00000106615	-0.7433402609133397	[15]	[8,7]	-7	hSpCas9	negative selection	3314235
151484741	151484764	7	-	27383988	293T	resistance to West Nile virus (flavivirus)	CTTCAACTTGTAGACACAGCCGG	RHEB	ENSG00000106615	0.009398698002249677	[151,151]	[0,0]	0	hSpCas9	positive selection	3389774
151490981	151491004	7	-	27383988	293T	resistance to West Nile virus (flavivirus)	TTGACGATTCAATTTGTTGAAGG	RHEB	ENSG00000106615	-0.4080097057393411	[202,202]	[0,0]	-3	hSpCas9	positive selection	3389775
151490958	151490981	7	+	27383988	293T	resistance to West Nile virus (flavivirus)	GATCGTAGGAGTCCACAAATTGG	RHEB	ENSG00000106615	1.6134700216711104	[49,49]	[0,0]	6	hSpCas9	positive selection	3389776
151484777	151484800	7	-	26780180	HT29	viability (Avana library 4 designs)	ACAAAGTTGATCACAGTAAATGG	RHEB	ENSG00000106615	1.98296741168361	[]	[]	7	hSpCas9	negative selection	3455094
151477375	151477398	7	+	26780180	HT29	viability (Avana library 4 designs)	ATATCTATGGAGTATGTCTGAGG	RHEB	ENSG00000106615	5.14327811938728	[]	[]	9	hSpCas9	negative selection	3455095
151484722	151484745	7	+	26780180	HT29	viability (Avana library 4 designs)	CCAGAGGTCACTTACTTGCCCGG	RHEB	ENSG00000106615	4.09957251735089	[]	[]	9	hSpCas9	negative selection	3455096
151484740	151484763	7	-	26780180	HT29	viability (Avana library 4 designs)	TTCAACTTGTAGACACAGCCGGG	RHEB	ENSG00000106615	0.0367480106452952	[]	[]	0	hSpCas9	negative selection	3455097
151484740	151484763	7	-	26780180	A375	viability (Avana lentiCRISPRv2)	TTCAACTTGTAGACACAGCCGGG	RHEB	ENSG00000106615	1.87268354945524	[]	[]	2	hSpCas9	negative selection	3552909
151484777	151484800	7	-	26780180	A375	viability (Avana lentiCRISPRv2)	ACAAAGTTGATCACAGTAAATGG	RHEB	ENSG00000106615	-7.05551960779437	[]	[]	-6	hSpCas9	negative selection	3552910
151477375	151477398	7	+	26780180	A375	viability (Avana lentiCRISPRv2)	ATATCTATGGAGTATGTCTGAGG	RHEB	ENSG00000106615	-9.24075520848071	[]	[]	-7	hSpCas9	negative selection	3552911
151484722	151484745	7	+	26780180	A375	viability (Avana lentiCRISPRv2)	CCAGAGGTCACTTACTTGCCCGG	RHEB	ENSG00000106615	0.712646245442119	[]	[]	1	hSpCas9	negative selection	3552912
151484740	151484763	7	-	26780180	A375	viability (Avana lentiGuide)	TTCAACTTGTAGACACAGCCGGG	RHEB	ENSG00000106615	-8.53860531233208	[]	[]	-9	hSpCas9	negative selection	3661568
151484777	151484800	7	-	26780180	A375	viability (Avana lentiGuide)	ACAAAGTTGATCACAGTAAATGG	RHEB	ENSG00000106615	1.72686022910787	[]	[]	2	hSpCas9	negative selection	3661569
151477375	151477398	7	+	26780180	A375	viability (Avana lentiGuide)	ATATCTATGGAGTATGTCTGAGG	RHEB	ENSG00000106615	12.3945559652607	[]	[]	7	hSpCas9	negative selection	3661570
151484722	151484745	7	+	26780180	A375	viability (Avana lentiGuide)	CCAGAGGTCACTTACTTGCCCGG	RHEB	ENSG00000106615	26.838352858921	[]	[]	9	hSpCas9	negative selection	3661571
151484740	151484763	7	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TTCAACTTGTAGACACAGCCGGG	RHEB	ENSG00000106615	0.08832495421514128	[5]	[4,5]	2	hSpCas9	positive selection	3770175
151484777	151484800	7	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ACAAAGTTGATCACAGTAAATGG	RHEB	ENSG00000106615	-0.3540352584183915	[9]	[7,6]	-5	hSpCas9	positive selection	3770176
151477375	151477398	7	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ATATCTATGGAGTATGTCTGAGG	RHEB	ENSG00000106615	-0.45208627278625846	[8]	[6,5]	-6	hSpCas9	positive selection	3770177
151484722	151484745	7	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CCAGAGGTCACTTACTTGCCCGG	RHEB	ENSG00000106615	0.20474126709923401	[4]	[5,5]	5	hSpCas9	positive selection	3770178
151484740	151484763	7	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TTCAACTTGTAGACACAGCCGGG	RHEB	ENSG00000106615	0.450111763846634	[5]	[6,5]	9	hSpCas9	positive selection	3878782
151484777	151484800	7	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ACAAAGTTGATCACAGTAAATGG	RHEB	ENSG00000106615	-0.24305826044611514	[6]	[4,3]	-3	hSpCas9	positive selection	3878783
151477375	151477398	7	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ATATCTATGGAGTATGTCTGAGG	RHEB	ENSG00000106615	-0.19452161205868243	[6]	[4,4]	-3	hSpCas9	positive selection	3878784
151484722	151484745	7	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CCAGAGGTCACTTACTTGCCCGG	RHEB	ENSG00000106615	-0.9893922674565565	[5]	[2,1]	-8	hSpCas9	positive selection	3878785
151471425	151471448	7	-	26780180	A375	viability	AAATAGAATACCTATTATGTTGG	RHEB	ENSG00000106615	1.20747438760667	[]	[]	6	hSpCas9	negative selection	3988917
151477332	151477355	7	-	26780180	A375	viability	ATTCTGTTACATCAATCAAAAGG	RHEB	ENSG00000106615	0.466501376895324	[]	[]	1	hSpCas9	negative selection	3988918
151471386	151471409	7	+	26780180	A375	viability	CTACATACCTTTCCATATGCAGG	RHEB	ENSG00000106615	1.09780483672908	[]	[]	5	hSpCas9	negative selection	3988919
151484741	151484764	7	-	26780180	A375	viability	CTTCAACTTGTAGACACAGCCGG	RHEB	ENSG00000106615	2.01609639919566	[]	[]	9	hSpCas9	negative selection	3988920
151490958	151490981	7	+	26780180	A375	viability	GATCGTAGGAGTCCACAAATTGG	RHEB	ENSG00000106615	1.38878655986447	[]	[]	7	hSpCas9	negative selection	3988921
151490981	151491004	7	-	26780180	A375	viability	TTGACGATTCAATTTGTTGAAGG	RHEB	ENSG00000106615	0.381858769218202	[]	[]	0	hSpCas9	negative selection	3988922
151471425	151471448	7	-	26780180	HT29	viability (GeCKOv2 library)	AAATAGAATACCTATTATGTTGG	RHEB	ENSG00000106615	1.21031351223609	[]	[]	6	hSpCas9	negative selection	4096883
151477332	151477355	7	-	26780180	HT29	viability (GeCKOv2 library)	ATTCTGTTACATCAATCAAAAGG	RHEB	ENSG00000106615	0.652976837660552	[]	[]	2	hSpCas9	negative selection	4096884
151471386	151471409	7	+	26780180	HT29	viability (GeCKOv2 library)	CTACATACCTTTCCATATGCAGG	RHEB	ENSG00000106615	2.15220742164093	[]	[]	9	hSpCas9	negative selection	4096885
151484741	151484764	7	-	26780180	HT29	viability (GeCKOv2 library)	CTTCAACTTGTAGACACAGCCGG	RHEB	ENSG00000106615	2.82052827490775	[]	[]	9	hSpCas9	negative selection	4096886
151490958	151490981	7	+	26780180	HT29	viability (GeCKOv2 library)	GATCGTAGGAGTCCACAAATTGG	RHEB	ENSG00000106615	1.48852653575681	[]	[]	7	hSpCas9	negative selection	4096887
151490981	151491004	7	-	26780180	HT29	viability (GeCKOv2 library)	TTGACGATTCAATTTGTTGAAGG	RHEB	ENSG00000106615	1.00060827255545	[]	[]	4	hSpCas9	negative selection	4096888
151490932	151490955	7	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	ACAATACTTACTGTTTTCTATGG	RHEB	ENSG00000106615	-0.3866767670594975	[2]	[0,1]	-7	hSpCas9	positive selection	4166333
151484741	151484764	7	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CTTCAACTTGTAGACACAGCCGG	RHEB	ENSG00000106615	-0.05255572738250208	[3]	[1,1]	-1	hSpCas9	positive selection	4166334
151490932	151490955	7	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	ACAATACTTACTGTTTTCTATGG	RHEB	ENSG00000106615	2.1195946934777785	[0]	[0,0,0,3]	9	hSpCas9	positive selection	4230355
151484741	151484764	7	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CTTCAACTTGTAGACACAGCCGG	RHEB	ENSG00000106615	-0.6495274638257044	[3]	[0,0,0,0]	-8	hSpCas9	positive selection	4230356
151471386	151471409	7	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CTACATACCTTTCCATATGCAGG	RHEB	ENSG00000106615	-0.177608159587173	[4]	[3,1]	-4	hSpCas9	positive selection	4294785
151477332	151477355	7	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ATTCTGTTACATCAATCAAAAGG	RHEB	ENSG00000106615	0.6957004258986307	[0]	[2,0]	9	hSpCas9	positive selection	4294786
151471425	151471448	7	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AAATAGAATACCTATTATGTTGG	RHEB	ENSG00000106615	0.20183647502871993	[2]	[2,2]	4	hSpCas9	positive selection	4294787
151484741	151484764	7	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CTTCAACTTGTAGACACAGCCGG	RHEB	ENSG00000106615	-0.6922282340368747	[3]	[2,0]	-9	hSpCas9	positive selection	4359040
151490981	151491004	7	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TTGACGATTCAATTTGTTGAAGG	RHEB	ENSG00000106615	0.20570456597031747	[2]	[4,1]	4	hSpCas9	positive selection	4359041
151490958	151490981	7	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GATCGTAGGAGTCCACAAATTGG	RHEB	ENSG00000106615	-0.4056637621793482	[1]	[1,0]	-7	hSpCas9	positive selection	4359042
151471563	151471585	7	+	27760321	OCIAML3	viability	CATATCCAACAATTTGCCATGG	RHEB	ENSG00000106615	-1.3043582154739386	[437,330]	[138,96]	-8	hSpCas9	negative selection	4434521
151477400	151477422	7	+	27760321	OCIAML3	viability	AGATAGAATATTCATCCTGTGG	RHEB	ENSG00000106615	-5.100441556830811	[53,34]	[0,0]	-9	hSpCas9	negative selection	4434522
151484741	151484763	7	-	27760321	OCIAML3	viability	TTCAACTTGTAGACACAGCCGG	RHEB	ENSG00000106615	-1.0333743750070272	[456,384]	[161,157]	-7	hSpCas9	negative selection	4434523
151484777	151484799	7	-	27760321	OCIAML3	viability	CAAAGTTGATCACAGTAAATGG	RHEB	ENSG00000106615	-3.355739800313153	[83,67]	[0,11]	-9	hSpCas9	negative selection	4434524
151490959	151490981	7	+	27760321	OCIAML3	viability	ATCGTAGGAGTCCACAAATTGG	RHEB	ENSG00000106615	-0.11854363031076964	[141,82]	[79,78]	-1	hSpCas9	negative selection	4434525
151471563	151471585	7	+	27760321	OCIAML2	viability	CATATCCAACAATTTGCCATGG	RHEB	ENSG00000106615	-1.3650026597678815	[437,330]	[89,158]	-8	hSpCas9	negative selection	4517984
151477400	151477422	7	+	27760321	OCIAML2	viability	AGATAGAATATTCATCCTGTGG	RHEB	ENSG00000106615	-2.4686851355340846	[53,34]	[8,2]	-9	hSpCas9	negative selection	4517985
151484741	151484763	7	-	27760321	OCIAML2	viability	TTCAACTTGTAGACACAGCCGG	RHEB	ENSG00000106615	-0.19735375275007552	[456,384]	[244,362]	-2	hSpCas9	negative selection	4517986
151484777	151484799	7	-	27760321	OCIAML2	viability	CAAAGTTGATCACAGTAAATGG	RHEB	ENSG00000106615	-2.032630877543315	[83,67]	[1,31]	-9	hSpCas9	negative selection	4517987
151490959	151490981	7	+	27760321	OCIAML2	viability	ATCGTAGGAGTCCACAAATTGG	RHEB	ENSG00000106615	-2.510086213737332	[141,82]	[19,9]	-9	hSpCas9	negative selection	4517988
151471563	151471585	7	+	27760321	MV411	viability	CATATCCAACAATTTGCCATGG	RHEB	ENSG00000106615	-0.33993909804490474	[437,330]	[0,495]	-2	hSpCas9	negative selection	4601447
151477400	151477422	7	+	27760321	MV411	viability	AGATAGAATATTCATCCTGTGG	RHEB	ENSG00000106615	-0.6085692230895456	[53,34]	[0,45]	-4	hSpCas9	negative selection	4601448
151484741	151484763	7	-	27760321	MV411	viability	TTCAACTTGTAGACACAGCCGG	RHEB	ENSG00000106615	-4.2259468214140785	[456,384]	[3,30]	-9	hSpCas9	negative selection	4601449
151484777	151484799	7	-	27760321	MV411	viability	CAAAGTTGATCACAGTAAATGG	RHEB	ENSG00000106615	-2.6780692234876207	[83,67]	[0,17]	-9	hSpCas9	negative selection	4601450
151490959	151490981	7	+	27760321	MV411	viability	ATCGTAGGAGTCCACAAATTGG	RHEB	ENSG00000106615	-1.330717943947639	[141,82]	[0,70]	-7	hSpCas9	negative selection	4601451
151471563	151471585	7	+	27760321	HL60	viability	CATATCCAACAATTTGCCATGG	RHEB	ENSG00000106615	-0.6002632394069906	[437,330]	[105,310]	-6	hSpCas9	negative selection	4684910
151477400	151477422	7	+	27760321	HL60	viability	AGATAGAATATTCATCCTGTGG	RHEB	ENSG00000106615	-1.6175335486249476	[53,34]	[0,22]	-8	hSpCas9	negative selection	4684911
151484741	151484763	7	-	27760321	HL60	viability	TTCAACTTGTAGACACAGCCGG	RHEB	ENSG00000106615	-1.540693561700542	[456,384]	[109,125]	-8	hSpCas9	negative selection	4684912
151484777	151484799	7	-	27760321	HL60	viability	CAAAGTTGATCACAGTAAATGG	RHEB	ENSG00000106615	-3.1470643574492363	[83,67]	[5,7]	-9	hSpCas9	negative selection	4684913
151490959	151490981	7	+	27760321	HL60	viability	ATCGTAGGAGTCCACAAATTGG	RHEB	ENSG00000106615	-1.3541080790360316	[141,82]	[44,24]	-8	hSpCas9	negative selection	4684914
151471563	151471585	7	+	27760321	HT1080	viability	CATATCCAACAATTTGCCATGG	RHEB	ENSG00000106615	-6.874191445397029	[330,257]	[0,0]	-9	hSpCas9	negative selection	4768373
151477400	151477422	7	+	27760321	HT1080	viability	AGATAGAATATTCATCCTGTGG	RHEB	ENSG00000106615	-3.6516721609785625	[34,27]	[0,0]	-8	hSpCas9	negative selection	4768374
151484741	151484763	7	-	27760321	HT1080	viability	TTCAACTTGTAGACACAGCCGG	RHEB	ENSG00000106615	-3.7624557252699553	[384,300]	[0,19]	-8	hSpCas9	negative selection	4768375
151484777	151484799	7	-	27760321	HT1080	viability	CAAAGTTGATCACAGTAAATGG	RHEB	ENSG00000106615	-4.590925769282425	[67,52]	[0,0]	-8	hSpCas9	negative selection	4768376
151490959	151490981	7	+	27760321	HT1080	viability	ATCGTAGGAGTCCACAAATTGG	RHEB	ENSG00000106615	-4.318927664239439	[82,64]	[0,1]	-8	hSpCas9	negative selection	4768377
151471563	151471585	7	+	27760321	HT29	viability after 7 days	CATATCCAACAATTTGCCATGG	RHEB	ENSG00000106615	-0.6628190220952546	[330,257]	[264,159,293]	-7	hSpCas9	negative selection	4851836
151477400	151477422	7	+	27760321	HT29	viability after 7 days	AGATAGAATATTCATCCTGTGG	RHEB	ENSG00000106615	-0.018233958744785284	[34,27]	[27,69,20]	0	hSpCas9	negative selection	4851837
151484741	151484763	7	-	27760321	HT29	viability after 7 days	TTCAACTTGTAGACACAGCCGG	RHEB	ENSG00000106615	-0.31564720875212443	[384,300]	[515,384,189]	-4	hSpCas9	negative selection	4851838
151484777	151484799	7	-	27760321	HT29	viability after 7 days	CAAAGTTGATCACAGTAAATGG	RHEB	ENSG00000106615	-1.059050651604056	[67,52]	[48,39,24]	-8	hSpCas9	negative selection	4851839
151490959	151490981	7	+	27760321	HT29	viability after 7 days	ATCGTAGGAGTCCACAAATTGG	RHEB	ENSG00000106615	-0.570596807286142	[82,64]	[106,18,71]	-7	hSpCas9	negative selection	4851840
151471563	151471585	7	+	27760321	HT29	viability after 25 days	CATATCCAACAATTTGCCATGG	RHEB	ENSG00000106615	-5.480320942146308	[330,257]	[0,5,16]	-9	hSpCas9	negative selection	4935299
151477400	151477422	7	+	27760321	HT29	viability after 25 days	AGATAGAATATTCATCCTGTGG	RHEB	ENSG00000106615	-5.171354425825086	[34,27]	[0,0,0]	-9	hSpCas9	negative selection	4935300
151484741	151484763	7	-	27760321	HT29	viability after 25 days	TTCAACTTGTAGACACAGCCGG	RHEB	ENSG00000106615	-3.465548251736104	[384,300]	[19,37,50]	-9	hSpCas9	negative selection	4935301
151484777	151484799	7	-	27760321	HT29	viability after 25 days	CAAAGTTGATCACAGTAAATGG	RHEB	ENSG00000106615	-4.965752473799926	[67,52]	[0,0,4]	-9	hSpCas9	negative selection	4935302
151490959	151490981	7	+	27760321	HT29	viability after 25 days	ATCGTAGGAGTCCACAAATTGG	RHEB	ENSG00000106615	-5.256767896644452	[82,64]	[0,0,4]	-9	hSpCas9	negative selection	4935303
151471563	151471585	7	+	27760321	HT29	viability after 22 days	CATATCCAACAATTTGCCATGG	RHEB	ENSG00000106615	-3.583846065251193	[330,257]	[11,4,68]	-9	hSpCas9	negative selection	5018762
151477400	151477422	7	+	27760321	HT29	viability after 22 days	AGATAGAATATTCATCCTGTGG	RHEB	ENSG00000106615	-5.188673057684346	[34,27]	[0,0,0]	-9	hSpCas9	negative selection	5018763
151484741	151484763	7	-	27760321	HT29	viability after 22 days	TTCAACTTGTAGACACAGCCGG	RHEB	ENSG00000106615	-5.182521364783708	[384,300]	[0,23,7]	-9	hSpCas9	negative selection	5018764
151484777	151484799	7	-	27760321	HT29	viability after 22 days	CAAAGTTGATCACAGTAAATGG	RHEB	ENSG00000106615	-4.029461050154707	[67,52]	[0,0,10]	-9	hSpCas9	negative selection	5018765
151490959	151490981	7	+	27760321	HT29	viability after 22 days	ATCGTAGGAGTCCACAAATTGG	RHEB	ENSG00000106615	-3.8524179193935124	[82,64]	[0,0,15]	-9	hSpCas9	negative selection	5018766
151471563	151471585	7	+	27760321	HT29	viability after 19 days	CATATCCAACAATTTGCCATGG	RHEB	ENSG00000106615	-4.643233975500649	[330,257]	[27,1,11]	-9	hSpCas9	negative selection	5102225
151477400	151477422	7	+	27760321	HT29	viability after 19 days	AGATAGAATATTCATCCTGTGG	RHEB	ENSG00000106615	-5.172833005261133	[34,27]	[0,0,0]	-9	hSpCas9	negative selection	5102226
151484741	151484763	7	-	27760321	HT29	viability after 19 days	TTCAACTTGTAGACACAGCCGG	RHEB	ENSG00000106615	-2.7679594869304407	[384,300]	[8,109,48]	-8	hSpCas9	negative selection	5102227
151484777	151484799	7	-	27760321	HT29	viability after 19 days	CAAAGTTGATCACAGTAAATGG	RHEB	ENSG00000106615	-6.112086613564994	[67,52]	[0,0,0]	-9	hSpCas9	negative selection	5102228
151490959	151490981	7	+	27760321	HT29	viability after 19 days	ATCGTAGGAGTCCACAAATTGG	RHEB	ENSG00000106615	-4.796691939305916	[82,64]	[0,6,0]	-9	hSpCas9	negative selection	5102229
151471563	151471585	7	+	27760321	HT29	viability after 16 days	CATATCCAACAATTTGCCATGG	RHEB	ENSG00000106615	-3.001111591463698	[330,257]	[18,92,7]	-9	hSpCas9	negative selection	5185688
151477400	151477422	7	+	27760321	HT29	viability after 16 days	AGATAGAATATTCATCCTGTGG	RHEB	ENSG00000106615	-3.223006864710988	[34,27]	[9,0,0]	-9	hSpCas9	negative selection	5185689
151484741	151484763	7	-	27760321	HT29	viability after 16 days	TTCAACTTGTAGACACAGCCGG	RHEB	ENSG00000106615	-2.664071179394009	[384,300]	[96,63,23]	-8	hSpCas9	negative selection	5185690
151484777	151484799	7	-	27760321	HT29	viability after 16 days	CAAAGTTGATCACAGTAAATGG	RHEB	ENSG00000106615	-3.8320367719015542	[67,52]	[0,0,11]	-9	hSpCas9	negative selection	5185691
151490959	151490981	7	+	27760321	HT29	viability after 16 days	ATCGTAGGAGTCCACAAATTGG	RHEB	ENSG00000106615	-5.983302827821923	[82,64]	[1,0,0]	-9	hSpCas9	negative selection	5185692
151471563	151471585	7	+	27760321	HT29	viability after 13 days	CATATCCAACAATTTGCCATGG	RHEB	ENSG00000106615	-2.295997213034254	[330,257]	[55,53,96]	-9	hSpCas9	negative selection	5269151
151477400	151477422	7	+	27760321	HT29	viability after 13 days	AGATAGAATATTCATCCTGTGG	RHEB	ENSG00000106615	-2.212966300336068	[34,27]	[2,0,18]	-9	hSpCas9	negative selection	5269152
151484741	151484763	7	-	27760321	HT29	viability after 13 days	TTCAACTTGTAGACACAGCCGG	RHEB	ENSG00000106615	-2.609059435765839	[384,300]	[63,71,59]	-9	hSpCas9	negative selection	5269153
151484777	151484799	7	-	27760321	HT29	viability after 13 days	CAAAGTTGATCACAGTAAATGG	RHEB	ENSG00000106615	-1.4149369311647213	[67,52]	[66,4,7]	-8	hSpCas9	negative selection	5269154
151490959	151490981	7	+	27760321	HT29	viability after 13 days	ATCGTAGGAGTCCACAAATTGG	RHEB	ENSG00000106615	-1.2276756307487018	[82,64]	[23,31,52]	-8	hSpCas9	negative selection	5269155
151471563	151471585	7	+	27760321	HT29	viability after 10 days	CATATCCAACAATTTGCCATGG	RHEB	ENSG00000106615	-2.2463623649058704	[330,257]	[24,131,76]	-9	hSpCas9	negative selection	5352614
151477400	151477422	7	+	27760321	HT29	viability after 10 days	AGATAGAATATTCATCCTGTGG	RHEB	ENSG00000106615	-0.6481451792606991	[34,27]	[11,22,39]	-6	hSpCas9	negative selection	5352615
151484741	151484763	7	-	27760321	HT29	viability after 10 days	TTCAACTTGTAGACACAGCCGG	RHEB	ENSG00000106615	-1.087146801296693	[384,300]	[280,210,114]	-8	hSpCas9	negative selection	5352616
151484777	151484799	7	-	27760321	HT29	viability after 10 days	CAAAGTTGATCACAGTAAATGG	RHEB	ENSG00000106615	-2.157521165041	[67,52]	[3,26,19]	-9	hSpCas9	negative selection	5352617
151490959	151490981	7	+	27760321	HT29	viability after 10 days	ATCGTAGGAGTCCACAAATTGG	RHEB	ENSG00000106615	-0.4864153934478961	[82,64]	[75,123,0]	-6	hSpCas9	negative selection	5352618
151471563	151471585	7	+	27760321	MOLM13	viability	CATATCCAACAATTTGCCATGG	RHEB	ENSG00000106615	-2.3013865022276088	[437,330]	[7,73]	-8	hSpCas9	negative selection	5436077
151477400	151477422	7	+	27760321	MOLM13	viability	AGATAGAATATTCATCCTGTGG	RHEB	ENSG00000106615	-4.629306175088534	[53,34]	[0,0]	-9	hSpCas9	negative selection	5436078
151484741	151484763	7	-	27760321	MOLM13	viability	TTCAACTTGTAGACACAGCCGG	RHEB	ENSG00000106615	-0.8190483082829028	[456,384]	[165,106]	-5	hSpCas9	negative selection	5436079
151484777	151484799	7	-	27760321	MOLM13	viability	CAAAGTTGATCACAGTAAATGG	RHEB	ENSG00000106615	-5.414443260212304	[83,67]	[0,0]	-9	hSpCas9	negative selection	5436080
151490959	151490981	7	+	27760321	MOLM13	viability	ATCGTAGGAGTCCACAAATTGG	RHEB	ENSG00000106615	-0.32990779919270397	[141,82]	[61,38]	-2	hSpCas9	negative selection	5436081
151519404	151519427	7	+	27661255	K562	viability	GCTCCCAGGCGAGGCCCCGGCGG	RHEB	ENSG00000106615	-0.3548627330578227	[83,152]	[69,75]	-7	dCas9-KRAB	negative selection	5507331
151519452	151519475	7	-	27661255	K562	viability	GCTACCGGTCTGTGGGTGAGTGG	RHEB	ENSG00000106615	-0.10660405449837698	[993,909]	[755,665]	-4	dCas9-KRAB	negative selection	5507332
151471386	151471409	7	+	27260156	BXPC3	viability	CTACATACCTTTCCATATGCAGG	RHEB	ENSG00000106615	-0.31274853667502156	[1245]	[874,1093,1039,1215]	-6	hSpCas9	negative selection	5567245
151477332	151477355	7	-	27260156	BXPC3	viability	ATTCTGTTACATCAATCAAAAGG	RHEB	ENSG00000106615	0.1547273564418732	[41]	[27,69,42,55]	3	hSpCas9	negative selection	5567246
151471425	151471448	7	-	27260156	BXPC3	viability	AAATAGAATACCTATTATGTTGG	RHEB	ENSG00000106615	-0.6574054599127341	[365]	[155,205,253,381]	-8	hSpCas9	negative selection	5567247
151484741	151484764	7	-	27260156	BXPC3	viability	CTTCAACTTGTAGACACAGCCGG	RHEB	ENSG00000106615	-0.5198448236380186	[791]	[469,568,618,672]	-8	hSpCas9	negative selection	5631500
151490981	151491004	7	-	27260156	BXPC3	viability	TTGACGATTCAATTTGTTGAAGG	RHEB	ENSG00000106615	0.3186677071295312	[457]	[536,612,628,613]	7	hSpCas9	negative selection	5631501
151490958	151490981	7	+	27260156	BXPC3	viability	GATCGTAGGAGTCCACAAATTGG	RHEB	ENSG00000106615	-0.7372750291458137	[191]	[113,122,69,180]	-9	hSpCas9	negative selection	5631502
151471386	151471409	7	+	27260156	A673	viability	CTACATACCTTTCCATATGCAGG	RHEB	ENSG00000106615	-0.4306220988879943	[1245]	[1142,1085,1064,1150]	-8	hSpCas9	negative selection	5688496
151477332	151477355	7	-	27260156	A673	viability	ATTCTGTTACATCAATCAAAAGG	RHEB	ENSG00000106615	0.37692438057661093	[41]	[69,66,64,59]	8	hSpCas9	negative selection	5688497
151471425	151471448	7	-	27260156	A673	viability	AAATAGAATACCTATTATGTTGG	RHEB	ENSG00000106615	-0.37234405301324347	[365]	[464,298,320,284]	-7	hSpCas9	negative selection	5688498
151484741	151484764	7	-	27260156	A673	viability	CTTCAACTTGTAGACACAGCCGG	RHEB	ENSG00000106615	-0.5718934736827146	[791]	[667,748,405,742]	-8	hSpCas9	negative selection	5752751
151490981	151491004	7	-	27260156	A673	viability	TTGACGATTCAATTTGTTGAAGG	RHEB	ENSG00000106615	0.28018828355435765	[457]	[643,624,682,718]	6	hSpCas9	negative selection	5752752
151490958	151490981	7	+	27260156	A673	viability	GATCGTAGGAGTCCACAAATTGG	RHEB	ENSG00000106615	-0.7007625641264064	[191]	[208,103,91,172]	-9	hSpCas9	negative selection	5752753
151471386	151471409	7	+	27260156	A375	viability	CTACATACCTTTCCATATGCAGG	RHEB	ENSG00000106615	-0.014603560809145044	[1245]	[1477,1003,1546,1642]	0	hSpCas9	negative selection	5809747
151477332	151477355	7	-	27260156	A375	viability	ATTCTGTTACATCAATCAAAAGG	RHEB	ENSG00000106615	0.8097281099235736	[41]	[106,96,70,71]	9	hSpCas9	negative selection	5809748
151471425	151471448	7	-	27260156	A375	viability	AAATAGAATACCTATTATGTTGG	RHEB	ENSG00000106615	-1.158511275862693	[365]	[242,222,213,100]	-8	hSpCas9	negative selection	5809749
151484741	151484764	7	-	27260156	A375	viability	CTTCAACTTGTAGACACAGCCGG	RHEB	ENSG00000106615	-0.5260103064142977	[791]	[532,661,776,601]	-6	hSpCas9	negative selection	5874002
151490981	151491004	7	-	27260156	A375	viability	TTGACGATTCAATTTGTTGAAGG	RHEB	ENSG00000106615	0.41229391951241356	[457]	[619,989,765,528]	6	hSpCas9	negative selection	5874003
151490958	151490981	7	+	27260156	A375	viability	GATCGTAGGAGTCCACAAATTGG	RHEB	ENSG00000106615	-0.594515068837604	[191]	[78,198,191,131]	-7	hSpCas9	negative selection	5874004
151471386	151471409	7	+	27260156	COLO741	viability	CTACATACCTTTCCATATGCAGG	RHEB	ENSG00000106615	-0.37065563736814955	[1245]	[1305,1140,1248]	-7	hSpCas9	negative selection	5930998
151477332	151477355	7	-	27260156	COLO741	viability	ATTCTGTTACATCAATCAAAAGG	RHEB	ENSG00000106615	0.5922650468846489	[41]	[84,36,117]	9	hSpCas9	negative selection	5930999
151471425	151471448	7	-	27260156	COLO741	viability	AAATAGAATACCTATTATGTTGG	RHEB	ENSG00000106615	-0.4646249082842987	[365]	[347,306,359]	-7	hSpCas9	negative selection	5931000
151484741	151484764	7	-	27260156	COLO741	viability	CTTCAACTTGTAGACACAGCCGG	RHEB	ENSG00000106615	-0.6190291657004479	[791]	[720,609,649]	-8	hSpCas9	negative selection	5995253
151490981	151491004	7	-	27260156	COLO741	viability	TTGACGATTCAATTTGTTGAAGG	RHEB	ENSG00000106615	0.21700907041913375	[457]	[838,530,681]	4	hSpCas9	negative selection	5995254
151490958	151490981	7	+	27260156	COLO741	viability	GATCGTAGGAGTCCACAAATTGG	RHEB	ENSG00000106615	-0.8222209963921459	[191]	[95,213,104]	-9	hSpCas9	negative selection	5995255
151471386	151471409	7	+	27260156	CAL120	viability	CTACATACCTTTCCATATGCAGG	RHEB	ENSG00000106615	-0.3547268654079363	[1245]	[1517,950,1213]	-5	hSpCas9	negative selection	6052249
151477332	151477355	7	-	27260156	CAL120	viability	ATTCTGTTACATCAATCAAAAGG	RHEB	ENSG00000106615	0.24055949904056595	[41]	[40,73,66]	3	hSpCas9	negative selection	6052250
151471425	151471448	7	-	27260156	CAL120	viability	AAATAGAATACCTATTATGTTGG	RHEB	ENSG00000106615	-0.9139490637719005	[365]	[284,228,217]	-8	hSpCas9	negative selection	6052251
151484741	151484764	7	-	27260156	CAL120	viability	CTTCAACTTGTAGACACAGCCGG	RHEB	ENSG00000106615	-0.9509928177507815	[791]	[392,461,653]	-8	hSpCas9	negative selection	6116504
151490981	151491004	7	-	27260156	CAL120	viability	TTGACGATTCAATTTGTTGAAGG	RHEB	ENSG00000106615	0.45340867017460024	[457]	[741,864,728]	6	hSpCas9	negative selection	6116505
151490958	151490981	7	+	27260156	CAL120	viability	GATCGTAGGAGTCCACAAATTGG	RHEB	ENSG00000106615	-0.4795522929392322	[191]	[130,153,221]	-6	hSpCas9	negative selection	6116506
151471386	151471409	7	+	27260156	CADOES1	viability	CTACATACCTTTCCATATGCAGG	RHEB	ENSG00000106615	-0.07833089778589142	[1245]	[912,1188,1167,1121]	-1	hSpCas9	negative selection	6173500
151477332	151477355	7	-	27260156	CADOES1	viability	ATTCTGTTACATCAATCAAAAGG	RHEB	ENSG00000106615	0.3451384383253431	[41]	[50,40,42,63]	6	hSpCas9	negative selection	6173501
151471425	151471448	7	-	27260156	CADOES1	viability	AAATAGAATACCTATTATGTTGG	RHEB	ENSG00000106615	-0.29564188210350406	[365]	[295,238,275,298]	-5	hSpCas9	negative selection	6173502
151484741	151484764	7	-	27260156	CADOES1	viability	CTTCAACTTGTAGACACAGCCGG	RHEB	ENSG00000106615	-0.48314554901180556	[791]	[528,505,516,556]	-7	hSpCas9	negative selection	6237755
151490981	151491004	7	-	27260156	CADOES1	viability	TTGACGATTCAATTTGTTGAAGG	RHEB	ENSG00000106615	0.3776601830382224	[457]	[568,506,445,696]	6	hSpCas9	negative selection	6237756
151490958	151490981	7	+	27260156	CADOES1	viability	GATCGTAGGAGTCCACAAATTGG	RHEB	ENSG00000106615	-0.7945512528813801	[191]	[96,59,169,83]	-8	hSpCas9	negative selection	6237757
151471386	151471409	7	+	27260156	EWS502	viability	CTACATACCTTTCCATATGCAGG	RHEB	ENSG00000106615	-0.43216354666431656	[1245]	[939,936,998,1043]	-6	hSpCas9	negative selection	6294751
151477332	151477355	7	-	27260156	EWS502	viability	ATTCTGTTACATCAATCAAAAGG	RHEB	ENSG00000106615	0.7500085056121946	[41]	[63,63,82,90]	9	hSpCas9	negative selection	6294752
151471425	151471448	7	-	27260156	EWS502	viability	AAATAGAATACCTATTATGTTGG	RHEB	ENSG00000106615	-0.2971453667089339	[365]	[362,278,286,327]	-5	hSpCas9	negative selection	6294753
151484741	151484764	7	-	27260156	EWS502	viability	CTTCAACTTGTAGACACAGCCGG	RHEB	ENSG00000106615	-0.6607238863297497	[791]	[439,651,505,527]	-8	hSpCas9	negative selection	6359006
151490981	151491004	7	-	27260156	EWS502	viability	TTGACGATTCAATTTGTTGAAGG	RHEB	ENSG00000106615	0.3006443440675816	[457]	[685,697,563,410]	5	hSpCas9	negative selection	6359007
151490958	151490981	7	+	27260156	EWS502	viability	GATCGTAGGAGTCCACAAATTGG	RHEB	ENSG00000106615	-0.8092731725215976	[191]	[70,200,144,43]	-8	hSpCas9	negative selection	6359008
151471386	151471409	7	+	27260156	EW8	viability	CTACATACCTTTCCATATGCAGG	RHEB	ENSG00000106615	-0.2469268136205598	[1245]	[1001,901,692,847]	-5	hSpCas9	negative selection	6416002
151477332	151477355	7	-	27260156	EW8	viability	ATTCTGTTACATCAATCAAAAGG	RHEB	ENSG00000106615	0.7562322978143765	[41]	[65,77,50,36]	9	hSpCas9	negative selection	6416003
151471425	151471448	7	-	27260156	EW8	viability	AAATAGAATACCTATTATGTTGG	RHEB	ENSG00000106615	-0.02504722643383217	[365]	[286,215,357,291]	0	hSpCas9	negative selection	6416004
151484741	151484764	7	-	27260156	EW8	viability	CTTCAACTTGTAGACACAGCCGG	RHEB	ENSG00000106615	-0.3220996323484823	[791]	[571,639,385,482]	-5	hSpCas9	negative selection	6480257
151490981	151491004	7	-	27260156	EW8	viability	TTGACGATTCAATTTGTTGAAGG	RHEB	ENSG00000106615	0.48448652451336943	[457]	[540,495,392,668]	8	hSpCas9	negative selection	6480258
151490958	151490981	7	+	27260156	EW8	viability	GATCGTAGGAGTCCACAAATTGG	RHEB	ENSG00000106615	-0.9345942230473097	[191]	[82,62,53,129]	-9	hSpCas9	negative selection	6480259
151471386	151471409	7	+	27260156	CORL105	viability	CTACATACCTTTCCATATGCAGG	RHEB	ENSG00000106615	-0.041751649498974475	[1245]	[1340,1664,1485,1179]	-1	hSpCas9	negative selection	6537253
151477332	151477355	7	-	27260156	CORL105	viability	ATTCTGTTACATCAATCAAAAGG	RHEB	ENSG00000106615	0.41343754134819166	[41]	[47,34,110,74]	7	hSpCas9	negative selection	6537254
151471425	151471448	7	-	27260156	CORL105	viability	AAATAGAATACCTATTATGTTGG	RHEB	ENSG00000106615	-0.2518190348842452	[365]	[318,306,387,428]	-5	hSpCas9	negative selection	6537255
151484741	151484764	7	-	27260156	CORL105	viability	CTTCAACTTGTAGACACAGCCGG	RHEB	ENSG00000106615	-0.44065499789267676	[791]	[595,610,794,745]	-7	hSpCas9	negative selection	6601508
151490981	151491004	7	-	27260156	CORL105	viability	TTGACGATTCAATTTGTTGAAGG	RHEB	ENSG00000106615	0.3383414479662046	[457]	[576,746,756,637]	6	hSpCas9	negative selection	6601509
151490958	151490981	7	+	27260156	CORL105	viability	GATCGTAGGAGTCCACAAATTGG	RHEB	ENSG00000106615	-0.8766763450044461	[191]	[94,81,214,111]	-9	hSpCas9	negative selection	6601510
151471386	151471409	7	+	27260156	HS294T	viability	CTACATACCTTTCCATATGCAGG	RHEB	ENSG00000106615	-0.2997440580659181	[1245]	[228,521,410,417]	-4	hSpCas9	negative selection	6658504
151477332	151477355	7	-	27260156	HS294T	viability	ATTCTGTTACATCAATCAAAAGG	RHEB	ENSG00000106615	0.17266828261343736	[41]	[15,22,16,16]	2	hSpCas9	negative selection	6658505
151471425	151471448	7	-	27260156	HS294T	viability	AAATAGAATACCTATTATGTTGG	RHEB	ENSG00000106615	-0.1598735755809454	[365]	[84,93,157,183]	-2	hSpCas9	negative selection	6658506
151484741	151484764	7	-	27260156	HS294T	viability	CTTCAACTTGTAGACACAGCCGG	RHEB	ENSG00000106615	-0.40020167566587384	[791]	[196,211,257,270]	-5	hSpCas9	negative selection	6722759
151490981	151491004	7	-	27260156	HS294T	viability	TTGACGATTCAATTTGTTGAAGG	RHEB	ENSG00000106615	0.6900411275300082	[457]	[226,283,238,419]	8	hSpCas9	negative selection	6722760
151490958	151490981	7	+	27260156	HS294T	viability	GATCGTAGGAGTCCACAAATTGG	RHEB	ENSG00000106615	-0.9821674306594055	[191]	[25,48,37,37]	-8	hSpCas9	negative selection	6722761
151471386	151471409	7	+	27260156	HCC44	viability	CTACATACCTTTCCATATGCAGG	RHEB	ENSG00000106615	-0.07050525118390638	[1245]	[1211,1139,1828,1278]	-1	hSpCas9	negative selection	6779755
151477332	151477355	7	-	27260156	HCC44	viability	ATTCTGTTACATCAATCAAAAGG	RHEB	ENSG00000106615	-0.3802923538469063	[41]	[13,4,34,91]	-5	hSpCas9	negative selection	6779756
151471425	151471448	7	-	27260156	HCC44	viability	AAATAGAATACCTATTATGTTGG	RHEB	ENSG00000106615	-0.15702762629772526	[365]	[301,259,659,320]	-3	hSpCas9	negative selection	6779757
151484741	151484764	7	-	27260156	HCC44	viability	CTTCAACTTGTAGACACAGCCGG	RHEB	ENSG00000106615	-0.8470638740019695	[791]	[714,361,585,382]	-8	hSpCas9	negative selection	6844010
151490981	151491004	7	-	27260156	HCC44	viability	TTGACGATTCAATTTGTTGAAGG	RHEB	ENSG00000106615	0.3053921767337872	[457]	[852,455,792,528]	5	hSpCas9	negative selection	6844011
151490958	151490981	7	+	27260156	HCC44	viability	GATCGTAGGAGTCCACAAATTGG	RHEB	ENSG00000106615	-0.5329882389933129	[191]	[146,66,312,112]	-7	hSpCas9	negative selection	6844012
151471386	151471409	7	+	27260156	G402	viability	CTACATACCTTTCCATATGCAGG	RHEB	ENSG00000106615	0.09498790853995587	[1245]	[1279,1150,1934,2025]	1	hSpCas9	negative selection	6901006
151477332	151477355	7	-	27260156	G402	viability	ATTCTGTTACATCAATCAAAAGG	RHEB	ENSG00000106615	0.14226535927570927	[41]	[51,85,30,57]	1	hSpCas9	negative selection	6901007
151471425	151471448	7	-	27260156	G402	viability	AAATAGAATACCTATTATGTTGG	RHEB	ENSG00000106615	-0.3255868397407793	[365]	[259,284,609,255]	-4	hSpCas9	negative selection	6901008
151484741	151484764	7	-	27260156	G402	viability	CTTCAACTTGTAGACACAGCCGG	RHEB	ENSG00000106615	-1.0117075928111707	[791]	[604,781,358,217]	-8	hSpCas9	negative selection	6965261
151490981	151491004	7	-	27260156	G402	viability	TTGACGATTCAATTTGTTGAAGG	RHEB	ENSG00000106615	0.7469850495323308	[457]	[809,908,1052,954]	8	hSpCas9	negative selection	6965262
151490958	151490981	7	+	27260156	G402	viability	GATCGTAGGAGTCCACAAATTGG	RHEB	ENSG00000106615	-1.467159564339965	[191]	[164,103,32,50]	-9	hSpCas9	negative selection	6965263
151471386	151471409	7	+	27260156	L33	viability	CTACATACCTTTCCATATGCAGG	RHEB	ENSG00000106615	-0.14315576524980078	[1245]	[1259,417,706,1104]	-3	hSpCas9	negative selection	7022257
151477332	151477355	7	-	27260156	L33	viability	ATTCTGTTACATCAATCAAAAGG	RHEB	ENSG00000106615	0.3032213557375365	[41]	[54,30,22,39]	6	hSpCas9	negative selection	7022258
151471425	151471448	7	-	27260156	L33	viability	AAATAGAATACCTATTATGTTGG	RHEB	ENSG00000106615	0.30450021780490805	[365]	[501,190,259,424]	6	hSpCas9	negative selection	7022259
151484741	151484764	7	-	27260156	L33	viability	CTTCAACTTGTAGACACAGCCGG	RHEB	ENSG00000106615	-0.243366701516742	[791]	[597,299,469,600]	-5	hSpCas9	negative selection	7086512
151490981	151491004	7	-	27260156	L33	viability	TTGACGATTCAATTTGTTGAAGG	RHEB	ENSG00000106615	0.36215021497749456	[457]	[500,340,280,575]	7	hSpCas9	negative selection	7086513
151490958	151490981	7	+	27260156	L33	viability	GATCGTAGGAGTCCACAAATTGG	RHEB	ENSG00000106615	-0.47699359495021154	[191]	[152,41,83,161]	-8	hSpCas9	negative selection	7086514
151471386	151471409	7	+	27260156	K562	viability	CTACATACCTTTCCATATGCAGG	RHEB	ENSG00000106615	-0.3006452325604341	[1245]	[1117,1106,397,982]	-4	hSpCas9	negative selection	7143508
151477332	151477355	7	-	27260156	K562	viability	ATTCTGTTACATCAATCAAAAGG	RHEB	ENSG00000106615	0.5367097973286263	[41]	[10,34,115,49]	6	hSpCas9	negative selection	7143509
151471425	151471448	7	-	27260156	K562	viability	AAATAGAATACCTATTATGTTGG	RHEB	ENSG00000106615	0.09914510538989219	[365]	[345,376,230,427]	1	hSpCas9	negative selection	7143510
151484741	151484764	7	-	27260156	K562	viability	CTTCAACTTGTAGACACAGCCGG	RHEB	ENSG00000106615	-0.6551304591449082	[791]	[613,547,340,314]	-6	hSpCas9	negative selection	7207763
151490981	151491004	7	-	27260156	K562	viability	TTGACGATTCAATTTGTTGAAGG	RHEB	ENSG00000106615	0.6950991122296123	[457]	[901,749,644,388]	8	hSpCas9	negative selection	7207764
151490958	151490981	7	+	27260156	K562	viability	GATCGTAGGAGTCCACAAATTGG	RHEB	ENSG00000106615	-1.4334094634787293	[191]	[32,130,80,13]	-9	hSpCas9	negative selection	7207765
151471386	151471409	7	+	27260156	HT29	viability	CTACATACCTTTCCATATGCAGG	RHEB	ENSG00000106615	-0.28617432548029487	[1245]	[1302,1075,1338,1232]	-5	hSpCas9	negative selection	7264759
151477332	151477355	7	-	27260156	HT29	viability	ATTCTGTTACATCAATCAAAAGG	RHEB	ENSG00000106615	0.19109391316881252	[41]	[86,49,36,59]	4	hSpCas9	negative selection	7264760
151471425	151471448	7	-	27260156	HT29	viability	AAATAGAATACCTATTATGTTGG	RHEB	ENSG00000106615	-1.049273729898831	[365]	[228,236,257,145]	-9	hSpCas9	negative selection	7264761
151484741	151484764	7	-	27260156	HT29	viability	CTTCAACTTGTAGACACAGCCGG	RHEB	ENSG00000106615	-0.9169497053663688	[791]	[507,603,566,380]	-8	hSpCas9	negative selection	7329014
151490981	151491004	7	-	27260156	HT29	viability	TTGACGATTCAATTTGTTGAAGG	RHEB	ENSG00000106615	0.26657164690859037	[457]	[674,602,803,595]	5	hSpCas9	negative selection	7329015
151490958	151490981	7	+	27260156	HT29	viability	GATCGTAGGAGTCCACAAATTGG	RHEB	ENSG00000106615	-0.7327035962783746	[191]	[120,122,228,90]	-8	hSpCas9	negative selection	7329016
151471386	151471409	7	+	27260156	MHHES1	viability	CTACATACCTTTCCATATGCAGG	RHEB	ENSG00000106615	0.017005232760500144	[1245]	[1681,1938,1316,912]	0	hSpCas9	negative selection	7386010
151477332	151477355	7	-	27260156	MHHES1	viability	ATTCTGTTACATCAATCAAAAGG	RHEB	ENSG00000106615	-1.7421448759223743	[41]	[25,4,12,12]	-9	hSpCas9	negative selection	7386011
151471425	151471448	7	-	27260156	MHHES1	viability	AAATAGAATACCTATTATGTTGG	RHEB	ENSG00000106615	-0.5890254326804675	[365]	[349,263,287,210]	-8	hSpCas9	negative selection	7386012
151484741	151484764	7	-	27260156	MHHES1	viability	CTTCAACTTGTAGACACAGCCGG	RHEB	ENSG00000106615	-0.4681935468648629	[791]	[1062,886,448,316]	-7	hSpCas9	negative selection	7450265
151490981	151491004	7	-	27260156	MHHES1	viability	TTGACGATTCAATTTGTTGAAGG	RHEB	ENSG00000106615	0.4207490439861873	[457]	[792,689,616,663]	7	hSpCas9	negative selection	7450266
151490958	151490981	7	+	27260156	MHHES1	viability	GATCGTAGGAGTCCACAAATTGG	RHEB	ENSG00000106615	-0.73433795025309	[191]	[142,127,176,81]	-8	hSpCas9	negative selection	7450267
151471386	151471409	7	+	27260156	MEWO	viability	CTACATACCTTTCCATATGCAGG	RHEB	ENSG00000106615	-0.32795602248772493	[1245]	[1143,835,847]	-6	hSpCas9	negative selection	7507261
151477332	151477355	7	-	27260156	MEWO	viability	ATTCTGTTACATCAATCAAAAGG	RHEB	ENSG00000106615	0.6420754739374042	[41]	[35,69,72]	9	hSpCas9	negative selection	7507262
151471425	151471448	7	-	27260156	MEWO	viability	AAATAGAATACCTATTATGTTGG	RHEB	ENSG00000106615	-0.5134915856191584	[365]	[255,174,291]	-8	hSpCas9	negative selection	7507263
151484741	151484764	7	-	27260156	MEWO	viability	CTTCAACTTGTAGACACAGCCGG	RHEB	ENSG00000106615	-0.49217791649946013	[791]	[617,510,468]	-8	hSpCas9	negative selection	7571516
151490981	151491004	7	-	27260156	MEWO	viability	TTGACGATTCAATTTGTTGAAGG	RHEB	ENSG00000106615	0.07693316863242351	[457]	[573,331,473]	1	hSpCas9	negative selection	7571517
151490958	151490981	7	+	27260156	MEWO	viability	GATCGTAGGAGTCCACAAATTGG	RHEB	ENSG00000106615	-2.363132297463658	[191]	[30,29,42]	-9	hSpCas9	negative selection	7571518
151471386	151471409	7	+	27260156	LNCAPCLONEFGC	viability	CTACATACCTTTCCATATGCAGG	RHEB	ENSG00000106615	-0.09653656099569652	[1245]	[822,1025,1477,963]	-1	hSpCas9	negative selection	7628512
151477332	151477355	7	-	27260156	LNCAPCLONEFGC	viability	ATTCTGTTACATCAATCAAAAGG	RHEB	ENSG00000106615	0.7357950266894728	[41]	[21,45,87,102]	9	hSpCas9	negative selection	7628513
151471425	151471448	7	-	27260156	LNCAPCLONEFGC	viability	AAATAGAATACCTATTATGTTGG	RHEB	ENSG00000106615	-0.5886248530465774	[365]	[207,186,225,263]	-7	hSpCas9	negative selection	7628514
151484741	151484764	7	-	27260156	LNCAPCLONEFGC	viability	CTTCAACTTGTAGACACAGCCGG	RHEB	ENSG00000106615	-0.80112193969832	[791]	[318,429,510,401]	-8	hSpCas9	negative selection	7692767
151490981	151491004	7	-	27260156	LNCAPCLONEFGC	viability	TTGACGATTCAATTTGTTGAAGG	RHEB	ENSG00000106615	0.4573534384925401	[457]	[438,614,766,485]	7	hSpCas9	negative selection	7692768
151490958	151490981	7	+	27260156	LNCAPCLONEFGC	viability	GATCGTAGGAGTCCACAAATTGG	RHEB	ENSG00000106615	-0.8332971565601293	[191]	[133,64,64,122]	-8	hSpCas9	negative selection	7692769
151471386	151471409	7	+	27260156	PANC0327	viability	CTACATACCTTTCCATATGCAGG	RHEB	ENSG00000106615	0.12315925884676915	[1245]	[1107,1009,972,1746]	1	hSpCas9	negative selection	7749763
151477332	151477355	7	-	27260156	PANC0327	viability	ATTCTGTTACATCAATCAAAAGG	RHEB	ENSG00000106615	1.432604351003555	[41]	[176,54,110,71]	9	hSpCas9	negative selection	7749764
151471425	151471448	7	-	27260156	PANC0327	viability	AAATAGAATACCTATTATGTTGG	RHEB	ENSG00000106615	-0.40156551093577286	[365]	[200,191,390,203]	-5	hSpCas9	negative selection	7749765
151484741	151484764	7	-	27260156	PANC0327	viability	CTTCAACTTGTAGACACAGCCGG	RHEB	ENSG00000106615	-0.5344581105147378	[791]	[460,360,584,549]	-6	hSpCas9	negative selection	7814018
151490981	151491004	7	-	27260156	PANC0327	viability	TTGACGATTCAATTTGTTGAAGG	RHEB	ENSG00000106615	0.6914770338720099	[457]	[682,510,739,714]	8	hSpCas9	negative selection	7814019
151490958	151490981	7	+	27260156	PANC0327	viability	GATCGTAGGAGTCCACAAATTGG	RHEB	ENSG00000106615	-1.2127585043271805	[191]	[59,112,15,98]	-9	hSpCas9	negative selection	7814020
151471386	151471409	7	+	27260156	NCIH2009	viability	CTACATACCTTTCCATATGCAGG	RHEB	ENSG00000106615	-0.22350861103005792	[1245]	[2025,1283,1269]	-3	hSpCas9	negative selection	7871014
151477332	151477355	7	-	27260156	NCIH2009	viability	ATTCTGTTACATCAATCAAAAGG	RHEB	ENSG00000106615	-0.19756597110447371	[41]	[32,41,74]	-3	hSpCas9	negative selection	7871015
151471425	151471448	7	-	27260156	NCIH2009	viability	AAATAGAATACCTATTATGTTGG	RHEB	ENSG00000106615	-1.0271184301719787	[365]	[358,233,180]	-8	hSpCas9	negative selection	7871016
151484741	151484764	7	-	27260156	NCIH2009	viability	CTTCAACTTGTAGACACAGCCGG	RHEB	ENSG00000106615	-0.582311842341207	[791]	[890,735,618]	-6	hSpCas9	negative selection	7935269
151490981	151491004	7	-	27260156	NCIH2009	viability	TTGACGATTCAATTTGTTGAAGG	RHEB	ENSG00000106615	0.29751009038611076	[457]	[1072,711,630]	4	hSpCas9	negative selection	7935270
151490958	151490981	7	+	27260156	NCIH2009	viability	GATCGTAGGAGTCCACAAATTGG	RHEB	ENSG00000106615	-1.0719527474546173	[191]	[122,164,92]	-8	hSpCas9	negative selection	7935271
151471386	151471409	7	+	27260156	NCIH1373	viability	CTACATACCTTTCCATATGCAGG	RHEB	ENSG00000106615	0.002426492692735316	[1245]	[1735,1231,1089,425]	0	hSpCas9	negative selection	7992265
151477332	151477355	7	-	27260156	NCIH1373	viability	ATTCTGTTACATCAATCAAAAGG	RHEB	ENSG00000106615	1.0686506015411834	[41]	[174,124,51,12]	9	hSpCas9	negative selection	7992266
151471425	151471448	7	-	27260156	NCIH1373	viability	AAATAGAATACCTATTATGTTGG	RHEB	ENSG00000106615	-0.6506342472677624	[365]	[167,106,422,91]	-6	hSpCas9	negative selection	7992267
151484741	151484764	7	-	27260156	NCIH1373	viability	CTTCAACTTGTAGACACAGCCGG	RHEB	ENSG00000106615	-0.2748386438167075	[791]	[561,458,1011,237]	-3	hSpCas9	negative selection	8056520
151490981	151491004	7	-	27260156	NCIH1373	viability	TTGACGATTCAATTTGTTGAAGG	RHEB	ENSG00000106615	0.32653692275865287	[457]	[444,699,694,182]	3	hSpCas9	negative selection	8056521
151490958	151490981	7	+	27260156	NCIH1373	viability	GATCGTAGGAGTCCACAAATTGG	RHEB	ENSG00000106615	-1.0753872761919712	[191]	[98,92,144,17]	-8	hSpCas9	negative selection	8056522
151471386	151471409	7	+	27260156	PATU8902	viability	CTACATACCTTTCCATATGCAGG	RHEB	ENSG00000106615	-0.22119038538508295	[1245]	[1589,1599,1281,1527]	-2	hSpCas9	negative selection	8113516
151477332	151477355	7	-	27260156	PATU8902	viability	ATTCTGTTACATCAATCAAAAGG	RHEB	ENSG00000106615	-1.0682597185493536	[41]	[90,5,3,13]	-7	hSpCas9	negative selection	8113517
151471425	151471448	7	-	27260156	PATU8902	viability	AAATAGAATACCTATTATGTTGG	RHEB	ENSG00000106615	-2.3297357870201205	[365]	[62,73,31,274]	-9	hSpCas9	negative selection	8113518
151484741	151484764	7	-	27260156	PATU8902	viability	CTTCAACTTGTAGACACAGCCGG	RHEB	ENSG00000106615	-1.0815094032479151	[791]	[292,337,580,900]	-7	hSpCas9	negative selection	8177771
151490981	151491004	7	-	27260156	PATU8902	viability	TTGACGATTCAATTTGTTGAAGG	RHEB	ENSG00000106615	0.7444197276240953	[457]	[955,1408,837,1132]	7	hSpCas9	negative selection	8177772
151490958	151490981	7	+	27260156	PATU8902	viability	GATCGTAGGAGTCCACAAATTGG	RHEB	ENSG00000106615	-2.2446273904178566	[191]	[45,78,34,72]	-9	hSpCas9	negative selection	8177773
151471386	151471409	7	+	27260156	PANC1	viability	CTACATACCTTTCCATATGCAGG	RHEB	ENSG00000106615	-0.48304403688370534	[1245]	[932,800,580,740]	-6	hSpCas9	negative selection	8234767
151477332	151477355	7	-	27260156	PANC1	viability	ATTCTGTTACATCAATCAAAAGG	RHEB	ENSG00000106615	0.5416276618204727	[41]	[37,79,63,35]	8	hSpCas9	negative selection	8234768
151471425	151471448	7	-	27260156	PANC1	viability	AAATAGAATACCTATTATGTTGG	RHEB	ENSG00000106615	-0.5722807271348653	[365]	[294,185,204,157]	-7	hSpCas9	negative selection	8234769
151484741	151484764	7	-	27260156	PANC1	viability	CTTCAACTTGTAGACACAGCCGG	RHEB	ENSG00000106615	-1.2701291642580834	[791]	[256,297,373,210]	-9	hSpCas9	negative selection	8299022
151490981	151491004	7	-	27260156	PANC1	viability	TTGACGATTCAATTTGTTGAAGG	RHEB	ENSG00000106615	0.5215194825883505	[457]	[534,813,533,438]	8	hSpCas9	negative selection	8299023
151490958	151490981	7	+	27260156	PANC1	viability	GATCGTAGGAGTCCACAAATTGG	RHEB	ENSG00000106615	-1.036416526080012	[191]	[68,86,72,90]	-8	hSpCas9	negative selection	8299024
151471386	151471409	7	+	27260156	PANC0813	viability	CTACATACCTTTCCATATGCAGG	RHEB	ENSG00000106615	-0.2570378881789559	[1245]	[1382,1239,1220,1075]	-4	hSpCas9	negative selection	8356018
151477332	151477355	7	-	27260156	PANC0813	viability	ATTCTGTTACATCAATCAAAAGG	RHEB	ENSG00000106615	0.8647826075969411	[41]	[131,76,46,105]	9	hSpCas9	negative selection	8356019
151471425	151471448	7	-	27260156	PANC0813	viability	AAATAGAATACCTATTATGTTGG	RHEB	ENSG00000106615	-0.6878069476890727	[365]	[363,222,274,216]	-7	hSpCas9	negative selection	8356020
151484741	151484764	7	-	27260156	PANC0813	viability	CTTCAACTTGTAGACACAGCCGG	RHEB	ENSG00000106615	-0.5747351011526644	[791]	[605,547,524,805]	-7	hSpCas9	negative selection	8420273
151490981	151491004	7	-	27260156	PANC0813	viability	TTGACGATTCAATTTGTTGAAGG	RHEB	ENSG00000106615	0.35173631597169075	[457]	[703,681,836,532]	5	hSpCas9	negative selection	8420274
151490958	151490981	7	+	27260156	PANC0813	viability	GATCGTAGGAGTCCACAAATTGG	RHEB	ENSG00000106615	-0.3196029511713032	[191]	[109,266,211,129]	-5	hSpCas9	negative selection	8420275
151471386	151471409	7	+	27260156	RDES	viability	CTACATACCTTTCCATATGCAGG	RHEB	ENSG00000106615	-0.06181045269534913	[1245]	[831,1487,1255,2089]	-1	hSpCas9	negative selection	8477269
151477332	151477355	7	-	27260156	RDES	viability	ATTCTGTTACATCAATCAAAAGG	RHEB	ENSG00000106615	0.019877448910377016	[41]	[30,80,44,35]	0	hSpCas9	negative selection	8477270
151471425	151471448	7	-	27260156	RDES	viability	AAATAGAATACCTATTATGTTGG	RHEB	ENSG00000106615	-0.4904788815855686	[365]	[244,198,385,399]	-7	hSpCas9	negative selection	8477271
151484741	151484764	7	-	27260156	RDES	viability	CTTCAACTTGTAGACACAGCCGG	RHEB	ENSG00000106615	-0.5312236448251446	[791]	[640,552,676,635]	-7	hSpCas9	negative selection	8541524
151490981	151491004	7	-	27260156	RDES	viability	TTGACGATTCAATTTGTTGAAGG	RHEB	ENSG00000106615	0.5008413598049726	[457]	[597,701,889,821]	7	hSpCas9	negative selection	8541525
151490958	151490981	7	+	27260156	RDES	viability	GATCGTAGGAGTCCACAAATTGG	RHEB	ENSG00000106615	-1.4888675273418843	[191]	[48,95,77,96]	-9	hSpCas9	negative selection	8541526
151471386	151471409	7	+	27260156	PC3	viability	CTACATACCTTTCCATATGCAGG	RHEB	ENSG00000106615	-0.25919508931271285	[1245]	[692,973,1693,1095]	-5	hSpCas9	negative selection	8598520
151477332	151477355	7	-	27260156	PC3	viability	ATTCTGTTACATCAATCAAAAGG	RHEB	ENSG00000106615	0.4839622523255054	[41]	[23,81,138,28]	8	hSpCas9	negative selection	8598521
151471425	151471448	7	-	27260156	PC3	viability	AAATAGAATACCTATTATGTTGG	RHEB	ENSG00000106615	0.23129205819109283	[365]	[202,566,650,435]	5	hSpCas9	negative selection	8598522
151484741	151484764	7	-	27260156	PC3	viability	CTTCAACTTGTAGACACAGCCGG	RHEB	ENSG00000106615	-0.3653709381232476	[791]	[319,586,1011,773]	-7	hSpCas9	negative selection	8662775
151490981	151491004	7	-	27260156	PC3	viability	TTGACGATTCAATTTGTTGAAGG	RHEB	ENSG00000106615	0.2573645499002271	[457]	[390,719,605,481]	5	hSpCas9	negative selection	8662776
151490958	151490981	7	+	27260156	PC3	viability	GATCGTAGGAGTCCACAAATTGG	RHEB	ENSG00000106615	-0.12014044055464046	[191]	[83,107,554,134]	-3	hSpCas9	negative selection	8662777
151471386	151471409	7	+	27260156	PATU8988T	viability	CTACATACCTTTCCATATGCAGG	RHEB	ENSG00000106615	-0.4538368156836998	[1245]	[836,1112,742,843]	-6	hSpCas9	negative selection	8719771
151477332	151477355	7	-	27260156	PATU8988T	viability	ATTCTGTTACATCAATCAAAAGG	RHEB	ENSG00000106615	0.7857243789714685	[41]	[73,56,72,74]	9	hSpCas9	negative selection	8719772
151471425	151471448	7	-	27260156	PATU8988T	viability	AAATAGAATACCTATTATGTTGG	RHEB	ENSG00000106615	-0.6770795365685531	[365]	[254,205,255,160]	-8	hSpCas9	negative selection	8719773
151484741	151484764	7	-	27260156	PATU8988T	viability	CTTCAACTTGTAGACACAGCCGG	RHEB	ENSG00000106615	-0.7224563406812671	[791]	[530,621,440,259]	-8	hSpCas9	negative selection	8784026
151490981	151491004	7	-	27260156	PATU8988T	viability	TTGACGATTCAATTTGTTGAAGG	RHEB	ENSG00000106615	0.22666489518231844	[457]	[337,508,672,550]	4	hSpCas9	negative selection	8784027
151490958	151490981	7	+	27260156	PATU8988T	viability	GATCGTAGGAGTCCACAAATTGG	RHEB	ENSG00000106615	0.044496787651553404	[191]	[335,59,208,143]	0	hSpCas9	negative selection	8784028
151471386	151471409	7	+	27260156	T47D	viability	CTACATACCTTTCCATATGCAGG	RHEB	ENSG00000106615	-0.033827746456201124	[1245]	[1335,1435,1363,1537]	0	hSpCas9	negative selection	8841022
151477332	151477355	7	-	27260156	T47D	viability	ATTCTGTTACATCAATCAAAAGG	RHEB	ENSG00000106615	0.6417235062283475	[41]	[60,78,64,100]	9	hSpCas9	negative selection	8841023
151471425	151471448	7	-	27260156	T47D	viability	AAATAGAATACCTATTATGTTGG	RHEB	ENSG00000106615	-0.27159931942263227	[365]	[379,356,322,352]	-5	hSpCas9	negative selection	8841024
151484741	151484764	7	-	27260156	T47D	viability	CTTCAACTTGTAGACACAGCCGG	RHEB	ENSG00000106615	-0.3628458255149934	[791]	[695,583,874,723]	-6	hSpCas9	negative selection	8905277
151490981	151491004	7	-	27260156	T47D	viability	TTGACGATTCAATTTGTTGAAGG	RHEB	ENSG00000106615	0.4206480380645715	[457]	[787,572,749,758]	8	hSpCas9	negative selection	8905278
151490958	151490981	7	+	27260156	T47D	viability	GATCGTAGGAGTCCACAAATTGG	RHEB	ENSG00000106615	-0.5162460688181767	[191]	[139,139,196,148]	-8	hSpCas9	negative selection	8905279
151471386	151471409	7	+	27260156	SU8686	viability	CTACATACCTTTCCATATGCAGG	RHEB	ENSG00000106615	-0.15150893770244656	[1245]	[928,1083,1280,1187]	-3	hSpCas9	negative selection	8962273
151477332	151477355	7	-	27260156	SU8686	viability	ATTCTGTTACATCAATCAAAAGG	RHEB	ENSG00000106615	0.6221013746970883	[41]	[62,67,43,82]	9	hSpCas9	negative selection	8962274
151471425	151471448	7	-	27260156	SU8686	viability	AAATAGAATACCTATTATGTTGG	RHEB	ENSG00000106615	-0.6221458062446255	[365]	[301,206,179,248]	-7	hSpCas9	negative selection	8962275
151484741	151484764	7	-	27260156	SU8686	viability	CTTCAACTTGTAGACACAGCCGG	RHEB	ENSG00000106615	-0.586472824078629	[791]	[389,552,587,578]	-7	hSpCas9	negative selection	9026528
151490981	151491004	7	-	27260156	SU8686	viability	TTGACGATTCAATTTGTTGAAGG	RHEB	ENSG00000106615	0.295232915323228	[457]	[496,363,558,890]	5	hSpCas9	negative selection	9026529
151490958	151490981	7	+	27260156	SU8686	viability	GATCGTAGGAGTCCACAAATTGG	RHEB	ENSG00000106615	-1.1095733863451387	[191]	[57,87,113,97]	-8	hSpCas9	negative selection	9026530
151471386	151471409	7	+	27260156	SKES1	viability	CTACATACCTTTCCATATGCAGG	RHEB	ENSG00000106615	-0.21618134264236755	[1245]	[1119,1263,933,991]	-5	hSpCas9	negative selection	9083524
151477332	151477355	7	-	27260156	SKES1	viability	ATTCTGTTACATCAATCAAAAGG	RHEB	ENSG00000106615	0.32755645338092254	[41]	[113,17,35,46]	6	hSpCas9	negative selection	9083525
151471425	151471448	7	-	27260156	SKES1	viability	AAATAGAATACCTATTATGTTGG	RHEB	ENSG00000106615	-0.37461469921186497	[365]	[231,362,283,250]	-7	hSpCas9	negative selection	9083526
151484741	151484764	7	-	27260156	SKES1	viability	CTTCAACTTGTAGACACAGCCGG	RHEB	ENSG00000106615	-0.34244236049881505	[791]	[792,715,498,525]	-6	hSpCas9	negative selection	9147779
151490981	151491004	7	-	27260156	SKES1	viability	TTGACGATTCAATTTGTTGAAGG	RHEB	ENSG00000106615	0.27656989042518815	[457]	[766,534,501,444]	6	hSpCas9	negative selection	9147780
151490958	151490981	7	+	27260156	SKES1	viability	GATCGTAGGAGTCCACAAATTGG	RHEB	ENSG00000106615	-1.2940155123116304	[191]	[78,84,42,102]	-9	hSpCas9	negative selection	9147781
151471386	151471409	7	+	27260156	TOV112D	viability	CTACATACCTTTCCATATGCAGG	RHEB	ENSG00000106615	-0.24305709571916423	[1245]	[912,1107,1094,1099]	-5	hSpCas9	negative selection	9204775
151477332	151477355	7	-	27260156	TOV112D	viability	ATTCTGTTACATCAATCAAAAGG	RHEB	ENSG00000106615	-0.1360678878663184	[41]	[24,31,40,51]	-3	hSpCas9	negative selection	9204776
151471425	151471448	7	-	27260156	TOV112D	viability	AAATAGAATACCTATTATGTTGG	RHEB	ENSG00000106615	-0.5124995827542204	[365]	[307,272,172,280]	-7	hSpCas9	negative selection	9204777
151484741	151484764	7	-	27260156	TOV112D	viability	CTTCAACTTGTAGACACAGCCGG	RHEB	ENSG00000106615	-0.7007577697427442	[791]	[621,463,538,335]	-8	hSpCas9	negative selection	9269030
151490981	151491004	7	-	27260156	TOV112D	viability	TTGACGATTCAATTTGTTGAAGG	RHEB	ENSG00000106615	0.38173736273823855	[457]	[514,901,421,617]	7	hSpCas9	negative selection	9269031
151490958	151490981	7	+	27260156	TOV112D	viability	GATCGTAGGAGTCCACAAATTGG	RHEB	ENSG00000106615	-1.1158411347823165	[191]	[82,116,135,26]	-9	hSpCas9	negative selection	9269032
151471386	151471409	7	+	27260156	TC71	viability	CTACATACCTTTCCATATGCAGG	RHEB	ENSG00000106615	-0.006557426239954145	[1245]	[1336,1370,1118,1508]	0	hSpCas9	negative selection	9326026
151477332	151477355	7	-	27260156	TC71	viability	ATTCTGTTACATCAATCAAAAGG	RHEB	ENSG00000106615	0.15982942809450096	[41]	[53,32,69,42]	4	hSpCas9	negative selection	9326027
151471425	151471448	7	-	27260156	TC71	viability	AAATAGAATACCTATTATGTTGG	RHEB	ENSG00000106615	-0.04509231517626666	[365]	[337,410,347,428]	-1	hSpCas9	negative selection	9326028
151484741	151484764	7	-	27260156	TC71	viability	CTTCAACTTGTAGACACAGCCGG	RHEB	ENSG00000106615	-0.5353947022742058	[791]	[635,553,561,590]	-9	hSpCas9	negative selection	9390281
151490981	151491004	7	-	27260156	TC71	viability	TTGACGATTCAATTTGTTGAAGG	RHEB	ENSG00000106615	0.18880859693155697	[457]	[528,530,548,634]	5	hSpCas9	negative selection	9390282
151490958	151490981	7	+	27260156	TC71	viability	GATCGTAGGAGTCCACAAATTGG	RHEB	ENSG00000106615	-0.5678669943293837	[191]	[128,169,110,146]	-9	hSpCas9	negative selection	9390283
151471386	151471409	7	+	27260156	TC32	viability	CTACATACCTTTCCATATGCAGG	RHEB	ENSG00000106615	0.02242271536809981	[1245]	[958,1193,1467,1131]	0	hSpCas9	negative selection	9447277
151477332	151477355	7	-	27260156	TC32	viability	ATTCTGTTACATCAATCAAAAGG	RHEB	ENSG00000106615	-0.39447045735501085	[41]	[41,0,40,46]	-6	hSpCas9	negative selection	9447278
151471425	151471448	7	-	27260156	TC32	viability	AAATAGAATACCTATTATGTTGG	RHEB	ENSG00000106615	-0.5019946842227432	[365]	[222,93,482,260]	-7	hSpCas9	negative selection	9447279
151484741	151484764	7	-	27260156	TC32	viability	CTTCAACTTGTAGACACAGCCGG	RHEB	ENSG00000106615	-0.33875616256939783	[791]	[625,360,841,617]	-6	hSpCas9	negative selection	9511532
151490981	151491004	7	-	27260156	TC32	viability	TTGACGATTCAATTTGTTGAAGG	RHEB	ENSG00000106615	0.4631475764364223	[457]	[469,491,878,600]	7	hSpCas9	negative selection	9511533
151490958	151490981	7	+	27260156	TC32	viability	GATCGTAGGAGTCCACAAATTGG	RHEB	ENSG00000106615	-1.4326323040201006	[191]	[89,39,35,100]	-9	hSpCas9	negative selection	9511534
151519448	151519471	7	+	28162770	P31FUJ	viability	CCGGCCACTCACCCACAGACCGG	RHEB	ENSG00000106615	-1.737691113437664	[402]	[141]	-8	hSpCas9	negative selection	10225024
151470610	151470633	7	-	28162770	P31FUJ	viability	GGAAAGCTTTGGCAGAATCTTGG	RHEB	ENSG00000106615	-0.19717829468365722	[359]	[368]	-2	hSpCas9	negative selection	10225025
151519491	151519514	7	-	28162770	P31FUJ	viability	AGATGCCGCAGTCCAAGTCCCGG	RHEB	ENSG00000106615	-1.1573948017563562	[409]	[215]	-7	hSpCas9	negative selection	10225026
151467202	151467225	7	-	28162770	P31FUJ	viability	TTTCTCTTTTCAGACTGCTGTGG	RHEB	ENSG00000106615	0.2295410096428218	[134]	[185]	2	hSpCas9	negative selection	10225027
151467144	151467167	7	-	28162770	P31FUJ	viability	ATGGACGGGGCAGCTTCACAAGG	RHEB	ENSG00000106615	-1.872007749919522	[270]	[86]	-8	hSpCas9	negative selection	10225028
151471557	151471580	7	-	28162770	P31FUJ	viability	GCAAATTGTTGGATATGGTGGGG	RHEB	ENSG00000106615	-1.7205960461285366	[243]	[86]	-8	hSpCas9	negative selection	10225029
151470632	151470655	7	-	28162770	P31FUJ	viability	AGGGTGATCAGTTATGAAGAAGG	RHEB	ENSG00000106615	-1.4614265794623411	[231]	[98]	-7	hSpCas9	negative selection	10225030
151471393	151471416	7	-	28162770	P31FUJ	viability	AGAAAGACCTGCATATGGAAAGG	RHEB	ENSG00000106615	-1.3725269680809917	[259]	[117]	-7	hSpCas9	negative selection	10225031
151490944	151490967	7	+	28162770	P31FUJ	viability	GTTTTCTATGGTTGGATCGTAGG	RHEB	ENSG00000106615	-1.3399581584425695	[460]	[213]	-7	hSpCas9	negative selection	10225032
151519460	151519483	7	-	28162770	P31FUJ	viability	GATCCTGGGCTACCGGTCTGTGG	RHEB	ENSG00000106615	-0.7236425277709846	[266]	[189]	-5	hSpCas9	negative selection	10225033
151519448	151519471	7	+	28162770	TF1	viability	CCGGCCACTCACCCACAGACCGG	RHEB	ENSG00000106615	NaN	[NaN]	[71]	1	hSpCas9	negative selection	10394390
151470610	151470633	7	-	28162770	TF1	viability	GGAAAGCTTTGGCAGAATCTTGG	RHEB	ENSG00000106615	NaN	[NaN]	[157]	1	hSpCas9	negative selection	10394391
151519491	151519514	7	-	28162770	TF1	viability	AGATGCCGCAGTCCAAGTCCCGG	RHEB	ENSG00000106615	NaN	[NaN]	[222]	1	hSpCas9	negative selection	10394392
151467202	151467225	7	-	28162770	TF1	viability	TTTCTCTTTTCAGACTGCTGTGG	RHEB	ENSG00000106615	NaN	[NaN]	[135]	1	hSpCas9	negative selection	10394393
151467144	151467167	7	-	28162770	TF1	viability	ATGGACGGGGCAGCTTCACAAGG	RHEB	ENSG00000106615	NaN	[NaN]	[93]	1	hSpCas9	negative selection	10394394
151471557	151471580	7	-	28162770	TF1	viability	GCAAATTGTTGGATATGGTGGGG	RHEB	ENSG00000106615	NaN	[NaN]	[15]	1	hSpCas9	negative selection	10394395
151470632	151470655	7	-	28162770	TF1	viability	AGGGTGATCAGTTATGAAGAAGG	RHEB	ENSG00000106615	NaN	[NaN]	[95]	1	hSpCas9	negative selection	10394396
151471393	151471416	7	-	28162770	TF1	viability	AGAAAGACCTGCATATGGAAAGG	RHEB	ENSG00000106615	NaN	[NaN]	[49]	1	hSpCas9	negative selection	10394397
151490944	151490967	7	+	28162770	TF1	viability	GTTTTCTATGGTTGGATCGTAGG	RHEB	ENSG00000106615	NaN	[NaN]	[249]	1	hSpCas9	negative selection	10394398
151519460	151519483	7	-	28162770	TF1	viability	GATCCTGGGCTACCGGTCTGTGG	RHEB	ENSG00000106615	NaN	[NaN]	[263]	1	hSpCas9	negative selection	10394399
151519448	151519471	7	+	28162770	SKM1	viability	CCGGCCACTCACCCACAGACCGG	RHEB	ENSG00000106615	-1.241378133025187	[110]	[82]	-7	hSpCas9	negative selection	10563756
151470610	151470633	7	-	28162770	SKM1	viability	GGAAAGCTTTGGCAGAATCTTGG	RHEB	ENSG00000106615	-0.6125483323930556	[63]	[73]	-5	hSpCas9	negative selection	10563757
151519491	151519514	7	-	28162770	SKM1	viability	AGATGCCGCAGTCCAAGTCCCGG	RHEB	ENSG00000106615	-0.5922146165144355	[138]	[162]	-5	hSpCas9	negative selection	10563758
151467202	151467225	7	-	28162770	SKM1	viability	TTTCTCTTTTCAGACTGCTGTGG	RHEB	ENSG00000106615	0.1515260906168034	[54]	[107]	1	hSpCas9	negative selection	10563759
151467144	151467167	7	-	28162770	SKM1	viability	ATGGACGGGGCAGCTTCACAAGG	RHEB	ENSG00000106615	-1.109578288118591	[82]	[67]	-7	hSpCas9	negative selection	10563760
151471557	151471580	7	-	28162770	SKM1	viability	GCAAATTGTTGGATATGGTGGGG	RHEB	ENSG00000106615	-1.5305388838616942	[66]	[40]	-7	hSpCas9	negative selection	10563761
151470632	151470655	7	-	28162770	SKM1	viability	AGGGTGATCAGTTATGAAGAAGG	RHEB	ENSG00000106615	-0.5000736031346431	[59]	[74]	-4	hSpCas9	negative selection	10563762
151471393	151471416	7	-	28162770	SKM1	viability	AGAAAGACCTGCATATGGAAAGG	RHEB	ENSG00000106615	-1.1439297929093677	[39]	[31]	-7	hSpCas9	negative selection	10563763
151490944	151490967	7	+	28162770	SKM1	viability	GTTTTCTATGGTTGGATCGTAGG	RHEB	ENSG00000106615	-0.48383296212743215	[105]	[133]	-4	hSpCas9	negative selection	10563764
151519460	151519483	7	-	28162770	SKM1	viability	GATCCTGGGCTACCGGTCTGTGG	RHEB	ENSG00000106615	-1.1183947008022301	[69]	[56]	-7	hSpCas9	negative selection	10563765
151519448	151519471	7	+	28162770	SKM1	viability	CCGGCCACTCACCCACAGACCGG	RHEB	ENSG00000106615	-1.241378133025187	[110]	[82]	-7	hSpCas9	negative selection	10733122
151470610	151470633	7	-	28162770	SKM1	viability	GGAAAGCTTTGGCAGAATCTTGG	RHEB	ENSG00000106615	-0.6125483323930556	[63]	[73]	-5	hSpCas9	negative selection	10733123
151519491	151519514	7	-	28162770	SKM1	viability	AGATGCCGCAGTCCAAGTCCCGG	RHEB	ENSG00000106615	-0.5922146165144355	[138]	[162]	-5	hSpCas9	negative selection	10733124
151467202	151467225	7	-	28162770	SKM1	viability	TTTCTCTTTTCAGACTGCTGTGG	RHEB	ENSG00000106615	0.1515260906168034	[54]	[107]	1	hSpCas9	negative selection	10733125
151467144	151467167	7	-	28162770	SKM1	viability	ATGGACGGGGCAGCTTCACAAGG	RHEB	ENSG00000106615	-1.109578288118591	[82]	[67]	-7	hSpCas9	negative selection	10733126
151471557	151471580	7	-	28162770	SKM1	viability	GCAAATTGTTGGATATGGTGGGG	RHEB	ENSG00000106615	-1.5305388838616942	[66]	[40]	-7	hSpCas9	negative selection	10733127
151470632	151470655	7	-	28162770	SKM1	viability	AGGGTGATCAGTTATGAAGAAGG	RHEB	ENSG00000106615	-0.5000736031346431	[59]	[74]	-4	hSpCas9	negative selection	10733128
151471393	151471416	7	-	28162770	SKM1	viability	AGAAAGACCTGCATATGGAAAGG	RHEB	ENSG00000106615	-1.1439297929093677	[39]	[31]	-7	hSpCas9	negative selection	10733129
151490944	151490967	7	+	28162770	SKM1	viability	GTTTTCTATGGTTGGATCGTAGG	RHEB	ENSG00000106615	-0.48383296212743215	[105]	[133]	-4	hSpCas9	negative selection	10733130
151519460	151519483	7	-	28162770	SKM1	viability	GATCCTGGGCTACCGGTCTGTGG	RHEB	ENSG00000106615	-1.1183947008022301	[69]	[56]	-7	hSpCas9	negative selection	10733131
151519448	151519471	7	+	28162770	PL21	viability	CCGGCCACTCACCCACAGACCGG	RHEB	ENSG00000106615	-2.334449363716717	[393]	[33]	-8	hSpCas9	negative selection	10902488
151470610	151470633	7	-	28162770	PL21	viability	GGAAAGCTTTGGCAGAATCTTGG	RHEB	ENSG00000106615	0.23232002023846998	[265]	[135]	2	hSpCas9	negative selection	10902489
151519491	151519514	7	-	28162770	PL21	viability	AGATGCCGCAGTCCAAGTCCCGG	RHEB	ENSG00000106615	-0.6855567588500749	[472]	[127]	-5	hSpCas9	negative selection	10902490
151467202	151467225	7	-	28162770	PL21	viability	TTTCTCTTTTCAGACTGCTGTGG	RHEB	ENSG00000106615	-0.028129373183797213	[245]	[104]	0	hSpCas9	negative selection	10902491
151467144	151467167	7	-	28162770	PL21	viability	ATGGACGGGGCAGCTTCACAAGG	RHEB	ENSG00000106615	-1.9222570168704065	[208]	[23]	-8	hSpCas9	negative selection	10902492
151471557	151471580	7	-	28162770	PL21	viability	GCAAATTGTTGGATATGGTGGGG	RHEB	ENSG00000106615	-1.1217884803980422	[194]	[38]	-6	hSpCas9	negative selection	10902493
151470632	151470655	7	-	28162770	PL21	viability	AGGGTGATCAGTTATGAAGAAGG	RHEB	ENSG00000106615	1.9424884053524298	[106]	[178]	9	hSpCas9	negative selection	10902494
151471393	151471416	7	-	28162770	PL21	viability	AGAAAGACCTGCATATGGAAAGG	RHEB	ENSG00000106615	-1.015366421261888	[208]	[44]	-6	hSpCas9	negative selection	10902495
151490944	151490967	7	+	28162770	PL21	viability	GTTTTCTATGGTTGGATCGTAGG	RHEB	ENSG00000106615	-1.9056550495332765	[395]	[45]	-8	hSpCas9	negative selection	10902496
151519460	151519483	7	-	28162770	PL21	viability	GATCCTGGGCTACCGGTCTGTGG	RHEB	ENSG00000106615	-0.9018813224511886	[248]	[57]	-6	hSpCas9	negative selection	10902497
151519448	151519471	7	+	28162770	P31FUJ	viability	CCGGCCACTCACCCACAGACCGG	RHEB	ENSG00000106615	-1.737691113437664	[402]	[141]	-8	hSpCas9	negative selection	11071854
151470610	151470633	7	-	28162770	P31FUJ	viability	GGAAAGCTTTGGCAGAATCTTGG	RHEB	ENSG00000106615	-0.19717829468365722	[359]	[368]	-2	hSpCas9	negative selection	11071855
151519491	151519514	7	-	28162770	P31FUJ	viability	AGATGCCGCAGTCCAAGTCCCGG	RHEB	ENSG00000106615	-1.1573948017563562	[409]	[215]	-7	hSpCas9	negative selection	11071856
151467202	151467225	7	-	28162770	P31FUJ	viability	TTTCTCTTTTCAGACTGCTGTGG	RHEB	ENSG00000106615	0.2295410096428218	[134]	[185]	2	hSpCas9	negative selection	11071857
151467144	151467167	7	-	28162770	P31FUJ	viability	ATGGACGGGGCAGCTTCACAAGG	RHEB	ENSG00000106615	-1.872007749919522	[270]	[86]	-8	hSpCas9	negative selection	11071858
151471557	151471580	7	-	28162770	P31FUJ	viability	GCAAATTGTTGGATATGGTGGGG	RHEB	ENSG00000106615	-1.7205960461285366	[243]	[86]	-8	hSpCas9	negative selection	11071859
151470632	151470655	7	-	28162770	P31FUJ	viability	AGGGTGATCAGTTATGAAGAAGG	RHEB	ENSG00000106615	-1.4614265794623411	[231]	[98]	-7	hSpCas9	negative selection	11071860
151471393	151471416	7	-	28162770	P31FUJ	viability	AGAAAGACCTGCATATGGAAAGG	RHEB	ENSG00000106615	-1.3725269680809917	[259]	[117]	-7	hSpCas9	negative selection	11071861
151490944	151490967	7	+	28162770	P31FUJ	viability	GTTTTCTATGGTTGGATCGTAGG	RHEB	ENSG00000106615	-1.3399581584425695	[460]	[213]	-7	hSpCas9	negative selection	11071862
151519460	151519483	7	-	28162770	P31FUJ	viability	GATCCTGGGCTACCGGTCTGTGG	RHEB	ENSG00000106615	-0.7236425277709846	[266]	[189]	-5	hSpCas9	negative selection	11071863
151519448	151519471	7	+	28162770	OCIAML5	viability	CCGGCCACTCACCCACAGACCGG	RHEB	ENSG00000106615	-1.740809819762256	[236]	[127]	-7	hSpCas9	negative selection	11241220
151470610	151470633	7	-	28162770	OCIAML5	viability	GGAAAGCTTTGGCAGAATCTTGG	RHEB	ENSG00000106615	-0.4312234499039475	[185]	[248]	-3	hSpCas9	negative selection	11241221
151519491	151519514	7	-	28162770	OCIAML5	viability	AGATGCCGCAGTCCAAGTCCCGG	RHEB	ENSG00000106615	-1.1820619470194742	[268]	[213]	-6	hSpCas9	negative selection	11241222
151467202	151467225	7	-	28162770	OCIAML5	viability	TTTCTCTTTTCAGACTGCTGTGG	RHEB	ENSG00000106615	0.21039751608265655	[112]	[235]	1	hSpCas9	negative selection	11241223
151467144	151467167	7	-	28162770	OCIAML5	viability	ATGGACGGGGCAGCTTCACAAGG	RHEB	ENSG00000106615	-2.0707068573393372	[127]	[54]	-8	hSpCas9	negative selection	11241224
151471557	151471580	7	-	28162770	OCIAML5	viability	GCAAATTGTTGGATATGGTGGGG	RHEB	ENSG00000106615	-1.4637959811479389	[135]	[88]	-7	hSpCas9	negative selection	11241225
151470632	151470655	7	-	28162770	OCIAML5	viability	AGGGTGATCAGTTATGAAGAAGG	RHEB	ENSG00000106615	-0.9082096489015307	[130]	[125]	-5	hSpCas9	negative selection	11241226
151471393	151471416	7	-	28162770	OCIAML5	viability	AGAAAGACCTGCATATGGAAAGG	RHEB	ENSG00000106615	-1.1366341382474319	[161]	[132]	-6	hSpCas9	negative selection	11241227
151490944	151490967	7	+	28162770	OCIAML5	viability	GTTTTCTATGGTTGGATCGTAGG	RHEB	ENSG00000106615	-1.54742736517249	[318]	[196]	-7	hSpCas9	negative selection	11241228
151519460	151519483	7	-	28162770	OCIAML5	viability	GATCCTGGGCTACCGGTCTGTGG	RHEB	ENSG00000106615	-1.724191748311839	[204]	[111]	-7	hSpCas9	negative selection	11241229
151519448	151519471	7	+	28162770	EOL1	viability	CCGGCCACTCACCCACAGACCGG	RHEB	ENSG00000106615	-1.8334794381235011	[689]	[101]	-8	hSpCas9	negative selection	11410586
151470610	151470633	7	-	28162770	EOL1	viability	GGAAAGCTTTGGCAGAATCTTGG	RHEB	ENSG00000106615	0.09178368548520677	[357]	[200]	0	hSpCas9	negative selection	11410587
151519491	151519514	7	-	28162770	EOL1	viability	AGATGCCGCAGTCCAAGTCCCGG	RHEB	ENSG00000106615	-1.56648304201195	[876]	[155]	-7	hSpCas9	negative selection	11410588
151467202	151467225	7	-	28162770	EOL1	viability	TTTCTCTTTTCAGACTGCTGTGG	RHEB	ENSG00000106615	0.7577286809960436	[347]	[309]	6	hSpCas9	negative selection	11410589
151467144	151467167	7	-	28162770	EOL1	viability	ATGGACGGGGCAGCTTCACAAGG	RHEB	ENSG00000106615	0.32953160618545563	[431]	[285]	3	hSpCas9	negative selection	11410590
151471557	151471580	7	-	28162770	EOL1	viability	GCAAATTGTTGGATATGGTGGGG	RHEB	ENSG00000106615	-2.429801801009205	[449]	[43]	-8	hSpCas9	negative selection	11410591
151470632	151470655	7	-	28162770	EOL1	viability	AGGGTGATCAGTTATGAAGAAGG	RHEB	ENSG00000106615	-1.709088575886311	[210]	[33]	-8	hSpCas9	negative selection	11410592
151471393	151471416	7	-	28162770	EOL1	viability	AGAAAGACCTGCATATGGAAAGG	RHEB	ENSG00000106615	-1.714052692752695	[273]	[43]	-8	hSpCas9	negative selection	11410593
151490944	151490967	7	+	28162770	EOL1	viability	GTTTTCTATGGTTGGATCGTAGG	RHEB	ENSG00000106615	-0.21828700660092026	[487]	[220]	-2	hSpCas9	negative selection	11410594
151519460	151519483	7	-	28162770	EOL1	viability	GATCCTGGGCTACCGGTCTGTGG	RHEB	ENSG00000106615	-1.979995069181561	[306]	[40]	-8	hSpCas9	negative selection	11410595
151519448	151519471	7	+	28162770	MOLM13	viability	CCGGCCACTCACCCACAGACCGG	RHEB	ENSG00000106615	-4.877040538704399	[568]	[13]	-9	hSpCas9	negative selection	11579952
151470610	151470633	7	-	28162770	MOLM13	viability	GGAAAGCTTTGGCAGAATCTTGG	RHEB	ENSG00000106615	-1.7158225716278093	[367]	[80]	-7	hSpCas9	negative selection	11579953
151519491	151519514	7	-	28162770	MOLM13	viability	AGATGCCGCAGTCCAAGTCCCGG	RHEB	ENSG00000106615	-1.2336273766173378	[669]	[205]	-6	hSpCas9	negative selection	11579954
151467202	151467225	7	-	28162770	MOLM13	viability	TTTCTCTTTTCAGACTGCTGTGG	RHEB	ENSG00000106615	-0.4039006361756809	[268]	[146]	-2	hSpCas9	negative selection	11579955
151467144	151467167	7	-	28162770	MOLM13	viability	ATGGACGGGGCAGCTTCACAAGG	RHEB	ENSG00000106615	-1.5321106184554212	[291]	[72]	-6	hSpCas9	negative selection	11579956
151471557	151471580	7	-	28162770	MOLM13	viability	GCAAATTGTTGGATATGGTGGGG	RHEB	ENSG00000106615	-6.002430553235454	[265]	[2]	-9	hSpCas9	negative selection	11579957
151470632	151470655	7	-	28162770	MOLM13	viability	AGGGTGATCAGTTATGAAGAAGG	RHEB	ENSG00000106615	-1.5082638765010534	[239]	[60]	-6	hSpCas9	negative selection	11579958
151471393	151471416	7	-	28162770	MOLM13	viability	AGAAAGACCTGCATATGGAAAGG	RHEB	ENSG00000106615	-2.8540387133427836	[349]	[34]	-8	hSpCas9	negative selection	11579959
151490944	151490967	7	+	28162770	MOLM13	viability	GTTTTCTATGGTTGGATCGTAGG	RHEB	ENSG00000106615	-3.794205463825601	[613]	[31]	-9	hSpCas9	negative selection	11579960
151519460	151519483	7	-	28162770	MOLM13	viability	GATCCTGGGCTACCGGTCTGTGG	RHEB	ENSG00000106615	-1.9177643109531708	[323]	[61]	-7	hSpCas9	negative selection	11579961
151519448	151519471	7	+	28162770	HEL	viability	CCGGCCACTCACCCACAGACCGG	RHEB	ENSG00000106615	0.26765071276922014	[462]	[356]	2	hSpCas9	negative selection	11749318
151470610	151470633	7	-	28162770	HEL	viability	GGAAAGCTTTGGCAGAATCTTGG	RHEB	ENSG00000106615	-0.7864659992050809	[306]	[113]	-5	hSpCas9	negative selection	11749319
151519491	151519514	7	-	28162770	HEL	viability	AGATGCCGCAGTCCAAGTCCCGG	RHEB	ENSG00000106615	0.06771456833531975	[650]	[436]	0	hSpCas9	negative selection	11749320
151467202	151467225	7	-	28162770	HEL	viability	TTTCTCTTTTCAGACTGCTGTGG	RHEB	ENSG00000106615	0.7996448869728077	[234]	[261]	7	hSpCas9	negative selection	11749321
151467144	151467167	7	-	28162770	HEL	viability	ATGGACGGGGCAGCTTCACAAGG	RHEB	ENSG00000106615	-1.0748614372989178	[295]	[89]	-6	hSpCas9	negative selection	11749322
151471557	151471580	7	-	28162770	HEL	viability	GCAAATTGTTGGATATGGTGGGG	RHEB	ENSG00000106615	-0.511294796672064	[315]	[141]	-3	hSpCas9	negative selection	11749323
151470632	151470655	7	-	28162770	HEL	viability	AGGGTGATCAGTTATGAAGAAGG	RHEB	ENSG00000106615	-1.3852755441692397	[207]	[50]	-7	hSpCas9	negative selection	11749324
151471393	151471416	7	-	28162770	HEL	viability	AGAAAGACCTGCATATGGAAAGG	RHEB	ENSG00000106615	-1.4843730859029822	[248]	[56]	-7	hSpCas9	negative selection	11749325
151490944	151490967	7	+	28162770	HEL	viability	GTTTTCTATGGTTGGATCGTAGG	RHEB	ENSG00000106615	-1.833813056491191	[550]	[98]	-7	hSpCas9	negative selection	11749326
151519460	151519483	7	-	28162770	HEL	viability	GATCCTGGGCTACCGGTCTGTGG	RHEB	ENSG00000106615	-0.24066341068579175	[296]	[160]	-2	hSpCas9	negative selection	11749327
151519448	151519471	7	+	28162770	MV411	viability	CCGGCCACTCACCCACAGACCGG	RHEB	ENSG00000106615	-4.744341942412256	[349]	[10]	-9	hSpCas9	negative selection	11918684
151470610	151470633	7	-	28162770	MV411	viability	GGAAAGCTTTGGCAGAATCTTGG	RHEB	ENSG00000106615	0.16711838627103748	[276]	[261]	1	hSpCas9	negative selection	11918685
151519491	151519514	7	-	28162770	MV411	viability	AGATGCCGCAGTCCAAGTCCCGG	RHEB	ENSG00000106615	-1.9541963103868751	[413]	[89]	-8	hSpCas9	negative selection	11918686
151467202	151467225	7	-	28162770	MV411	viability	TTTCTCTTTTCAGACTGCTGTGG	RHEB	ENSG00000106615	-0.14727996411647273	[187]	[142]	-1	hSpCas9	negative selection	11918687
151467144	151467167	7	-	28162770	MV411	viability	ATGGACGGGGCAGCTTCACAAGG	RHEB	ENSG00000106615	-1.9255088026347742	[238]	[52]	-8	hSpCas9	negative selection	11918688
151471557	151471580	7	-	28162770	MV411	viability	GCAAATTGTTGGATATGGTGGGG	RHEB	ENSG00000106615	-3.379345125633008	[209]	[16]	-9	hSpCas9	negative selection	11918689
151470632	151470655	7	-	28162770	MV411	viability	AGGGTGATCAGTTATGAAGAAGG	RHEB	ENSG00000106615	-0.9452075271596206	[159]	[69]	-6	hSpCas9	negative selection	11918690
151471393	151471416	7	-	28162770	MV411	viability	AGAAAGACCTGCATATGGAAAGG	RHEB	ENSG00000106615	-1.852098122768139	[209]	[48]	-8	hSpCas9	negative selection	11918691
151490944	151490967	7	+	28162770	MV411	viability	GTTTTCTATGGTTGGATCGTAGG	RHEB	ENSG00000106615	-0.9215156115922122	[370]	[164]	-6	hSpCas9	negative selection	11918692
151519460	151519483	7	-	28162770	MV411	viability	GATCCTGGGCTACCGGTCTGTGG	RHEB	ENSG00000106615	-0.7790346605784159	[274]	[134]	-5	hSpCas9	negative selection	11918693
151519448	151519471	7	+	28162770	MONOMAC1	viability	CCGGCCACTCACCCACAGACCGG	RHEB	ENSG00000106615	-0.43686386173202235	[221]	[187]	-4	hSpCas9	negative selection	12088050
151470610	151470633	7	-	28162770	MONOMAC1	viability	GGAAAGCTTTGGCAGAATCTTGG	RHEB	ENSG00000106615	-1.1145746868675808	[169]	[89]	-7	hSpCas9	negative selection	12088051
151519491	151519514	7	-	28162770	MONOMAC1	viability	AGATGCCGCAGTCCAAGTCCCGG	RHEB	ENSG00000106615	-2.507530046884632	[376]	[75]	-9	hSpCas9	negative selection	12088052
151467202	151467225	7	-	28162770	MONOMAC1	viability	TTTCTCTTTTCAGACTGCTGTGG	RHEB	ENSG00000106615	-0.6240469880044734	[120]	[89]	-5	hSpCas9	negative selection	12088053
151467144	151467167	7	-	28162770	MONOMAC1	viability	ATGGACGGGGCAGCTTCACAAGG	RHEB	ENSG00000106615	-0.9818687524910185	[142]	[82]	-6	hSpCas9	negative selection	12088054
151471557	151471580	7	-	28162770	MONOMAC1	viability	GCAAATTGTTGGATATGGTGGGG	RHEB	ENSG00000106615	-3.2374511155054617	[180]	[21]	-9	hSpCas9	negative selection	12088055
151470632	151470655	7	-	28162770	MONOMAC1	viability	AGGGTGATCAGTTATGAAGAAGG	RHEB	ENSG00000106615	-0.671945802315796	[81]	[58]	-5	hSpCas9	negative selection	12088056
151471393	151471416	7	-	28162770	MONOMAC1	viability	AGAAAGACCTGCATATGGAAAGG	RHEB	ENSG00000106615	-2.78199934778071	[149]	[24]	-9	hSpCas9	negative selection	12088057
151490944	151490967	7	+	28162770	MONOMAC1	viability	GTTTTCTATGGTTGGATCGTAGG	RHEB	ENSG00000106615	-1.0150390133166662	[237]	[134]	-7	hSpCas9	negative selection	12088058
151519460	151519483	7	-	28162770	MONOMAC1	viability	GATCCTGGGCTACCGGTCTGTGG	RHEB	ENSG00000106615	-1.858234933607795	[135]	[42]	-8	hSpCas9	negative selection	12088059
151519448	151519471	7	+	28162770	OCIAML2	viability	CCGGCCACTCACCCACAGACCGG	RHEB	ENSG00000106615	-1.541513311398671	[72]	[138]	-7	hSpCas9	negative selection	12257416
151470610	151470633	7	-	28162770	OCIAML2	viability	GGAAAGCTTTGGCAGAATCTTGG	RHEB	ENSG00000106615	-1.0691134656169363	[66]	[176]	-6	hSpCas9	negative selection	12257417
151519491	151519514	7	-	28162770	OCIAML2	viability	AGATGCCGCAGTCCAAGTCCCGG	RHEB	ENSG00000106615	-1.3976503798850557	[105]	[222]	-7	hSpCas9	negative selection	12257418
151467202	151467225	7	-	28162770	OCIAML2	viability	TTTCTCTTTTCAGACTGCTGTGG	RHEB	ENSG00000106615	0.7772976882014241	[41]	[398]	7	hSpCas9	negative selection	12257419
151467144	151467167	7	-	28162770	OCIAML2	viability	ATGGACGGGGCAGCTTCACAAGG	RHEB	ENSG00000106615	-0.9391065834824655	[54]	[158]	-6	hSpCas9	negative selection	12257420
151471557	151471580	7	-	28162770	OCIAML2	viability	GCAAATTGTTGGATATGGTGGGG	RHEB	ENSG00000106615	-3.0720804487518865	[43]	[28]	-9	hSpCas9	negative selection	12257421
151470632	151470655	7	-	28162770	OCIAML2	viability	AGGGTGATCAGTTATGAAGAAGG	RHEB	ENSG00000106615	-0.544630406685938	[29]	[113]	-4	hSpCas9	negative selection	12257422
151471393	151471416	7	-	28162770	OCIAML2	viability	AGAAAGACCTGCATATGGAAAGG	RHEB	ENSG00000106615	-1.0955903938952365	[31]	[82]	-6	hSpCas9	negative selection	12257423
151490944	151490967	7	+	28162770	OCIAML2	viability	GTTTTCTATGGTTGGATCGTAGG	RHEB	ENSG00000106615	-0.8989031516776991	[72]	[216]	-6	hSpCas9	negative selection	12257424
151519460	151519483	7	-	28162770	OCIAML2	viability	GATCCTGGGCTACCGGTCTGTGG	RHEB	ENSG00000106615	-0.7612199535965165	[36]	[120]	-5	hSpCas9	negative selection	12257425
151519448	151519471	7	+	28162770	OCIAML3	viability	CCGGCCACTCACCCACAGACCGG	RHEB	ENSG00000106615	-3.2805081675073815	[102]	[31]	-9	hSpCas9	negative selection	12426782
151470610	151470633	7	-	28162770	OCIAML3	viability	GGAAAGCTTTGGCAGAATCTTGG	RHEB	ENSG00000106615	-0.2431004784650348	[68]	[175]	-2	hSpCas9	negative selection	12426783
151519491	151519514	7	-	28162770	OCIAML3	viability	AGATGCCGCAGTCCAAGTCCCGG	RHEB	ENSG00000106615	-1.605595614599375	[124]	[123]	-8	hSpCas9	negative selection	12426784
151467202	151467225	7	-	28162770	OCIAML3	viability	TTTCTCTTTTCAGACTGCTGTGG	RHEB	ENSG00000106615	0.6499179425619261	[56]	[269]	6	hSpCas9	negative selection	12426785
151467144	151467167	7	-	28162770	OCIAML3	viability	ATGGACGGGGCAGCTTCACAAGG	RHEB	ENSG00000106615	0.4409261497852239	[50]	[208]	4	hSpCas9	negative selection	12426786
151471557	151471580	7	-	28162770	OCIAML3	viability	GCAAATTGTTGGATATGGTGGGG	RHEB	ENSG00000106615	-3.039807393373694	[78]	[28]	-9	hSpCas9	negative selection	12426787
151470632	151470655	7	-	28162770	OCIAML3	viability	AGGGTGATCAGTTATGAAGAAGG	RHEB	ENSG00000106615	-0.36080846403113237	[56]	[133]	-3	hSpCas9	negative selection	12426788
151471393	151471416	7	-	28162770	OCIAML3	viability	AGAAAGACCTGCATATGGAAAGG	RHEB	ENSG00000106615	-0.17505509104193612	[45]	[122]	-1	hSpCas9	negative selection	12426789
151490944	151490967	7	+	28162770	OCIAML3	viability	GTTTTCTATGGTTGGATCGTAGG	RHEB	ENSG00000106615	-1.3178832350499257	[127]	[154]	-7	hSpCas9	negative selection	12426790
151519460	151519483	7	-	28162770	OCIAML3	viability	GATCCTGGGCTACCGGTCTGTGG	RHEB	ENSG00000106615	-3.816400061660611	[69]	[14]	-9	hSpCas9	negative selection	12426791