Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:55781
• Symbol:RIOK2
• Description:RIO kinase 2

DataSource: http://genomecrispr.dkfz.de/#!/results/RIOK2

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
97167774	97167797	5	-	26472758	Jiyoye	viability	GAACTGTCTAGAAGAATCAGAGG	RIOK2	ENSG00000058729	0.12477565080514852	[134]	[110]	1	hSpCas9	negative selection	137311
97171196	97171219	5	+	26472758	Jiyoye	viability	AAGTACGTACCACTCAGCATTGG	RIOK2	ENSG00000058729	-1.7571140852670064	[510]	[113]	-8	hSpCas9	negative selection	137312
97167554	97167577	5	-	26472758	Jiyoye	viability	GATGGTCAGAGAGTTCAAGGAGG	RIOK2	ENSG00000058729	-0.4312807578394706	[210]	[117]	-3	hSpCas9	negative selection	137313
97179117	97179140	5	-	26472758	Jiyoye	viability	ATAGCCAGCCTTAAACATGGTGG	RIOK2	ENSG00000058729	0.21873029209276318	[48]	[42]	1	hSpCas9	negative selection	137314
97177743	97177766	5	-	26472758	Jiyoye	viability	GTTGGAAACCAGATGGGTGTTGG	RIOK2	ENSG00000058729	3.5771003829481853	[0]	[8]	9	hSpCas9	negative selection	137315
97167953	97167976	5	-	26472758	Jiyoye	viability	GATGTGGAGGTTTCTGCCAGTGG	RIOK2	ENSG00000058729	-2.1522520271081453	[111]	[18]	-8	hSpCas9	negative selection	137316
97167494	97167517	5	+	26472758	Jiyoye	viability	GACGACAAGGCAATTAGATGAGG	RIOK2	ENSG00000058729	-2.9407479219144337	[111]	[10]	-9	hSpCas9	negative selection	137317
97183125	97183148	5	-	26472758	Jiyoye	viability	TGACTTCAGGGTCTTGACCGCGG	RIOK2	ENSG00000058729	-3.762749619936439	[269]	[14]	-9	hSpCas9	negative selection	137318
97177164	97177187	5	-	26472758	Jiyoye	viability	AACATAGGCACAATGTGTCATGG	RIOK2	ENSG00000058729	0.170475123485542	[151]	[128]	1	hSpCas9	negative selection	137319
97171221	97171244	5	+	26472758	Jiyoye	viability	TGAGAAGTTGAAACCATCTGTGG	RIOK2	ENSG00000058729	-2.6056486588517105	[338]	[41]	-9	hSpCas9	negative selection	137320
97167774	97167797	5	-	26472758	KBM7	viability	GAACTGTCTAGAAGAATCAGAGG	RIOK2	ENSG00000058729	-0.5402257645371882	[988,732]	[331,224]	-5	hSpCas9	negative selection	328429
97171196	97171219	5	+	26472758	KBM7	viability	AAGTACGTACCACTCAGCATTGG	RIOK2	ENSG00000058729	-0.7551886375840817	[1902,2048]	[503,600]	-6	hSpCas9	negative selection	328430
97167554	97167577	5	-	26472758	KBM7	viability	GATGGTCAGAGAGTTCAAGGAGG	RIOK2	ENSG00000058729	-0.3693075292861578	[921,779]	[428,200]	-3	hSpCas9	negative selection	328431
97179117	97179140	5	-	26472758	KBM7	viability	ATAGCCAGCCTTAAACATGGTGG	RIOK2	ENSG00000058729	-1.3286961948886276	[534,399]	[64,105]	-7	hSpCas9	negative selection	328432
97177743	97177766	5	-	26472758	KBM7	viability	GTTGGAAACCAGATGGGTGTTGG	RIOK2	ENSG00000058729	-1.7430272349922702	[88,85]	[24,0]	-8	hSpCas9	negative selection	328433
97167953	97167976	5	-	26472758	KBM7	viability	GATGTGGAGGTTTCTGCCAGTGG	RIOK2	ENSG00000058729	-1.2565083172681275	[340,262]	[78,40]	-7	hSpCas9	negative selection	328434
97167494	97167517	5	+	26472758	KBM7	viability	GACGACAAGGCAATTAGATGAGG	RIOK2	ENSG00000058729	-0.9276669689203741	[394,457]	[158,59]	-6	hSpCas9	negative selection	328435
97183125	97183148	5	-	26472758	KBM7	viability	TGACTTCAGGGTCTTGACCGCGG	RIOK2	ENSG00000058729	-3.0846652865581037	[1390,1168]	[95,47]	-9	hSpCas9	negative selection	328436
97177164	97177187	5	-	26472758	KBM7	viability	AACATAGGCACAATGTGTCATGG	RIOK2	ENSG00000058729	0.4280050778918747	[928,978]	[446,751]	4	hSpCas9	negative selection	328437
97171221	97171244	5	+	26472758	KBM7	viability	TGAGAAGTTGAAACCATCTGTGG	RIOK2	ENSG00000058729	-1.3800893988015535	[1002,1197]	[171,227]	-7	hSpCas9	negative selection	328438
97167774	97167797	5	-	26472758	Raji	viability	GAACTGTCTAGAAGAATCAGAGG	RIOK2	ENSG00000058729	-1.3930454551358888	[463]	[40]	-7	hSpCas9	negative selection	519547
97171196	97171219	5	+	26472758	Raji	viability	AAGTACGTACCACTCAGCATTGG	RIOK2	ENSG00000058729	-1.873889256557495	[994]	[62]	-8	hSpCas9	negative selection	519548
97167554	97167577	5	-	26472758	Raji	viability	GATGGTCAGAGAGTTCAAGGAGG	RIOK2	ENSG00000058729	-1.178018683488649	[428]	[43]	-7	hSpCas9	negative selection	519549
97179117	97179140	5	-	26472758	Raji	viability	ATAGCCAGCCTTAAACATGGTGG	RIOK2	ENSG00000058729	-2.10506608271527	[240]	[12]	-8	hSpCas9	negative selection	519550
97177743	97177766	5	-	26472758	Raji	viability	GTTGGAAACCAGATGGGTGTTGG	RIOK2	ENSG00000058729	-2.593056182767493	[25]	[0]	-9	hSpCas9	negative selection	519551
97167953	97167976	5	-	26472758	Raji	viability	GATGTGGAGGTTTCTGCCAGTGG	RIOK2	ENSG00000058729	-2.4908757879610146	[217]	[8]	-9	hSpCas9	negative selection	519552
97167494	97167517	5	+	26472758	Raji	viability	GACGACAAGGCAATTAGATGAGG	RIOK2	ENSG00000058729	-1.9706189766276738	[151]	[8]	-8	hSpCas9	negative selection	519553
97183125	97183148	5	-	26472758	Raji	viability	TGACTTCAGGGTCTTGACCGCGG	RIOK2	ENSG00000058729	-3.740195864293503	[690]	[11]	-9	hSpCas9	negative selection	519554
97177164	97177187	5	-	26472758	Raji	viability	AACATAGGCACAATGTGTCATGG	RIOK2	ENSG00000058729	0.4231064807342537	[465]	[144]	4	hSpCas9	negative selection	519555
97171221	97171244	5	+	26472758	Raji	viability	TGAGAAGTTGAAACCATCTGTGG	RIOK2	ENSG00000058729	-0.9105383726236629	[566]	[69]	-6	hSpCas9	negative selection	519556
97167774	97167797	5	-	26472758	K562	viability	GAACTGTCTAGAAGAATCAGAGG	RIOK2	ENSG00000058729	-0.21911237862821464	[836]	[606]	-1	hSpCas9	negative selection	710665
97171196	97171219	5	+	26472758	K562	viability	AAGTACGTACCACTCAGCATTGG	RIOK2	ENSG00000058729	-2.387849487833066	[1518]	[244]	-8	hSpCas9	negative selection	710666
97167554	97167577	5	-	26472758	K562	viability	GATGGTCAGAGAGTTCAAGGAGG	RIOK2	ENSG00000058729	-0.4336531774461906	[895]	[559]	-3	hSpCas9	negative selection	710667
97179117	97179140	5	-	26472758	K562	viability	ATAGCCAGCCTTAAACATGGTGG	RIOK2	ENSG00000058729	-1.2091283347189936	[366]	[133]	-6	hSpCas9	negative selection	710668
97177743	97177766	5	-	26472758	K562	viability	GTTGGAAACCAGATGGGTGTTGG	RIOK2	ENSG00000058729	-0.6401040549136168	[23]	[12]	-4	hSpCas9	negative selection	710669
97167953	97167976	5	-	26472758	K562	viability	GATGTGGAGGTTTCTGCCAGTGG	RIOK2	ENSG00000058729	-0.6539410104577156	[273]	[146]	-4	hSpCas9	negative selection	710670
97167494	97167517	5	+	26472758	K562	viability	GACGACAAGGCAATTAGATGAGG	RIOK2	ENSG00000058729	-2.6144052093728587	[427]	[58]	-8	hSpCas9	negative selection	710671
97183125	97183148	5	-	26472758	K562	viability	TGACTTCAGGGTCTTGACCGCGG	RIOK2	ENSG00000058729	-3.0615873719327427	[810]	[81]	-8	hSpCas9	negative selection	710672
97177164	97177187	5	-	26472758	K562	viability	AACATAGGCACAATGTGTCATGG	RIOK2	ENSG00000058729	-0.19159492701871428	[992]	[733]	-1	hSpCas9	negative selection	710673
97171221	97171244	5	+	26472758	K562	viability	TGAGAAGTTGAAACCATCTGTGG	RIOK2	ENSG00000058729	-3.2205831490137964	[1037]	[93]	-8	hSpCas9	negative selection	710674
97167953	97167976	5	-	26627737	DLD1	viability	GATGTGGAGGTTTCTGCCAGTGG	RIOK2	ENSG00000058729	-2.75411129523574	[206]	[10,3,12]	-9	hSpCas9	negative selection	829846
97171363	97171386	5	+	26627737	DLD1	viability	CTGATGCAGGATCTTCAACATGG	RIOK2	ENSG00000058729	-1.914209188148439	[1339]	[42,149,137]	-8	hSpCas9	negative selection	829847
97177822	97177845	5	+	26627737	DLD1	viability	CATTTGTCAACCGATAGCCCTGG	RIOK2	ENSG00000058729	-4.181565162309389	[581]	[8,21,0]	-9	hSpCas9	negative selection	829848
97179113	97179136	5	+	26627737	DLD1	viability	ACAGCCACCATGTTTAAGGCTGG	RIOK2	ENSG00000058729	-2.6681376191281005	[383]	[8,45,4]	-9	hSpCas9	negative selection	829849
97183095	97183118	5	+	26627737	DLD1	viability	GAAGGGAGAACAGGAACGGCGGG	RIOK2	ENSG00000058729	-0.1978511171744124	[145]	[68,14,34]	-2	hSpCas9	negative selection	829850
97167953	97167976	5	-	26627737	GBM cells	viability after 5 days	GATGTGGAGGTTTCTGCCAGTGG	RIOK2	ENSG00000058729	-2.5473423550038783	[108]	[15,3]	-9	hSpCas9	negative selection	912161
97171363	97171386	5	+	26627737	GBM cells	viability after 5 days	CTGATGCAGGATCTTCAACATGG	RIOK2	ENSG00000058729	-0.7942302775648868	[788]	[251,235]	-8	hSpCas9	negative selection	912162
97177822	97177845	5	+	26627737	GBM cells	viability after 5 days	CATTTGTCAACCGATAGCCCTGG	RIOK2	ENSG00000058729	-1.4014810584520354	[132]	[19,33]	-9	hSpCas9	negative selection	912163
97179113	97179136	5	+	26627737	GBM cells	viability after 5 days	ACAGCCACCATGTTTAAGGCTGG	RIOK2	ENSG00000058729	-0.6565226735322987	[265]	[107,72]	-8	hSpCas9	negative selection	912164
97183095	97183118	5	+	26627737	GBM cells	viability after 5 days	GAAGGGAGAACAGGAACGGCGGG	RIOK2	ENSG00000058729	0.2708826522726433	[50]	[48,16]	4	hSpCas9	negative selection	912165
97167953	97167976	5	-	26627737	GBM cells	viability after 13 days	GATGTGGAGGTTTCTGCCAGTGG	RIOK2	ENSG00000058729	-1.2537274394306919	[108]	[42,9]	-8	hSpCas9	negative selection	994476
97171363	97171386	5	+	26627737	GBM cells	viability after 13 days	CTGATGCAGGATCTTCAACATGG	RIOK2	ENSG00000058729	-1.6710260110215214	[788]	[177,98]	-9	hSpCas9	negative selection	994477
97177822	97177845	5	+	26627737	GBM cells	viability after 13 days	CATTTGTCAACCGATAGCCCTGG	RIOK2	ENSG00000058729	-2.4460596872668052	[132]	[15,10]	-9	hSpCas9	negative selection	994478
97179113	97179136	5	+	26627737	GBM cells	viability after 13 days	ACAGCCACCATGTTTAAGGCTGG	RIOK2	ENSG00000058729	-0.975673501569059	[265]	[95,54]	-8	hSpCas9	negative selection	994479
97183095	97183118	5	+	26627737	GBM cells	viability after 13 days	GAAGGGAGAACAGGAACGGCGGG	RIOK2	ENSG00000058729	-1.3630710055049007	[50]	[7,12]	-8	hSpCas9	negative selection	994480
97167953	97167976	5	-	26627737	GBM cells	viability after 21 days	GATGTGGAGGTTTCTGCCAGTGG	RIOK2	ENSG00000058729	-5.887951025161268	[108]	[0,0]	-9	hSpCas9	negative selection	1076791
97171363	97171386	5	+	26627737	GBM cells	viability after 21 days	CTGATGCAGGATCTTCAACATGG	RIOK2	ENSG00000058729	-2.3907955223155373	[788]	[87,75]	-9	hSpCas9	negative selection	1076792
97177822	97177845	5	+	26627737	GBM cells	viability after 21 days	CATTTGTCAACCGATAGCCCTGG	RIOK2	ENSG00000058729	-1.7156175172482337	[132]	[21,21]	-8	hSpCas9	negative selection	1076793
97179113	97179136	5	+	26627737	GBM cells	viability after 21 days	ACAGCCACCATGTTTAAGGCTGG	RIOK2	ENSG00000058729	-1.466310094525952	[265]	[56,47]	-8	hSpCas9	negative selection	1076794
97183095	97183118	5	+	26627737	GBM cells	viability after 21 days	GAAGGGAGAACAGGAACGGCGGG	RIOK2	ENSG00000058729	-3.457496651394597	[50]	[1,2]	-9	hSpCas9	negative selection	1076795
97167953	97167976	5	-	26627737	RPE1	viability after 9 days	GATGTGGAGGTTTCTGCCAGTGG	RIOK2	ENSG00000058729	-4.251525845063079	[538]	[0,18]	-9	hSpCas9	negative selection	1159106
97171363	97171386	5	+	26627737	RPE1	viability after 9 days	CTGATGCAGGATCTTCAACATGG	RIOK2	ENSG00000058729	-3.0441588482887694	[2125]	[112,38]	-9	hSpCas9	negative selection	1159107
97177822	97177845	5	+	26627737	RPE1	viability after 9 days	CATTTGTCAACCGATAGCCCTGG	RIOK2	ENSG00000058729	-3.014388632595443	[272]	[17,0]	-9	hSpCas9	negative selection	1159108
97179113	97179136	5	+	26627737	RPE1	viability after 9 days	ACAGCCACCATGTTTAAGGCTGG	RIOK2	ENSG00000058729	-2.3634759257096616	[1098]	[27,116]	-9	hSpCas9	negative selection	1159109
97183095	97183118	5	+	26627737	RPE1	viability after 9 days	GAAGGGAGAACAGGAACGGCGGG	RIOK2	ENSG00000058729	-3.6925815941191074	[291]	[10,1]	-9	hSpCas9	negative selection	1159110
97167953	97167976	5	-	26627737	RPE1	viability after 12 days	GATGTGGAGGTTTCTGCCAGTGG	RIOK2	ENSG00000058729	-7.178030051079368	[538]	[0,0]	-9	hSpCas9	negative selection	1241421
97171363	97171386	5	+	26627737	RPE1	viability after 12 days	CTGATGCAGGATCTTCAACATGG	RIOK2	ENSG00000058729	-4.759620480742537	[2125]	[23,17]	-9	hSpCas9	negative selection	1241422
97177822	97177845	5	+	26627737	RPE1	viability after 12 days	CATTTGTCAACCGATAGCCCTGG	RIOK2	ENSG00000058729	-3.5844617597905337	[272]	[9,1]	-9	hSpCas9	negative selection	1241423
97179113	97179136	5	+	26627737	RPE1	viability after 12 days	ACAGCCACCATGTTTAAGGCTGG	RIOK2	ENSG00000058729	-2.04628120205524	[1098]	[19,125]	-8	hSpCas9	negative selection	1241424
97183095	97183118	5	+	26627737	RPE1	viability after 12 days	GAAGGGAGAACAGGAACGGCGGG	RIOK2	ENSG00000058729	-3.93918038688759	[291]	[8,0]	-9	hSpCas9	negative selection	1241425
97167953	97167976	5	-	26627737	RPE1	viability after 15 days	GATGTGGAGGTTTCTGCCAGTGG	RIOK2	ENSG00000058729	-5.650126192071859	[538]	[0,4]	-9	hSpCas9	negative selection	1323736
97171363	97171386	5	+	26627737	RPE1	viability after 15 days	CTGATGCAGGATCTTCAACATGG	RIOK2	ENSG00000058729	-4.324307539430832	[2125]	[56,3]	-9	hSpCas9	negative selection	1323737
97177822	97177845	5	+	26627737	RPE1	viability after 15 days	CATTTGTCAACCGATAGCCCTGG	RIOK2	ENSG00000058729	-0.8704765193258253	[272]	[84,0]	-5	hSpCas9	negative selection	1323738
97179113	97179136	5	+	26627737	RPE1	viability after 15 days	ACAGCCACCATGTTTAAGGCTGG	RIOK2	ENSG00000058729	-2.9556898496872157	[1098]	[35,43]	-9	hSpCas9	negative selection	1323739
97183095	97183118	5	+	26627737	RPE1	viability after 15 days	GAAGGGAGAACAGGAACGGCGGG	RIOK2	ENSG00000058729	-5.381191184798381	[291]	[2,0]	-9	hSpCas9	negative selection	1323740
97167953	97167976	5	-	26627737	RPE1	viability after 18 days	GATGTGGAGGTTTCTGCCAGTGG	RIOK2	ENSG00000058729	-4.639957344874491	[538]	[0,10]	-9	hSpCas9	negative selection	1406051
97171363	97171386	5	+	26627737	RPE1	viability after 18 days	CTGATGCAGGATCTTCAACATGG	RIOK2	ENSG00000058729	-4.406839962461097	[2125]	[42,9]	-9	hSpCas9	negative selection	1406052
97177822	97177845	5	+	26627737	RPE1	viability after 18 days	CATTTGTCAACCGATAGCCCTGG	RIOK2	ENSG00000058729	-6.203088880819109	[272]	[0,0]	-9	hSpCas9	negative selection	1406053
97179113	97179136	5	+	26627737	RPE1	viability after 18 days	ACAGCCACCATGTTTAAGGCTGG	RIOK2	ENSG00000058729	-1.8875616346967865	[1098]	[40,121]	-8	hSpCas9	negative selection	1406054
97183095	97183118	5	+	26627737	RPE1	viability after 18 days	GAAGGGAGAACAGGAACGGCGGG	RIOK2	ENSG00000058729	-1.5876700463359659	[291]	[17,34]	-7	hSpCas9	negative selection	1406055
97167953	97167976	5	-	26627737	HeLa	viability after 8 days	GATGTGGAGGTTTCTGCCAGTGG	RIOK2	ENSG00000058729	0.16021249712844576	[137]	[40,93,60]	1	hSpCas9	negative selection	1488366
97171363	97171386	5	+	26627737	HeLa	viability after 8 days	CTGATGCAGGATCTTCAACATGG	RIOK2	ENSG00000058729	-0.05973512516699642	[1185]	[798,490,277]	0	hSpCas9	negative selection	1488367
97177822	97177845	5	+	26627737	HeLa	viability after 8 days	CATTTGTCAACCGATAGCCCTGG	RIOK2	ENSG00000058729	-2.5930401148522337	[204]	[0,5,32]	-9	hSpCas9	negative selection	1488368
97179113	97179136	5	+	26627737	HeLa	viability after 8 days	ACAGCCACCATGTTTAAGGCTGG	RIOK2	ENSG00000058729	0.2709642617430228	[172]	[55,164,46]	2	hSpCas9	negative selection	1488369
97183095	97183118	5	+	26627737	HeLa	viability after 8 days	GAAGGGAGAACAGGAACGGCGGG	RIOK2	ENSG00000058729	-1.4291103249855455	[189]	[61,35,2]	-9	hSpCas9	negative selection	1488370
97167953	97167976	5	-	26627737	HeLa	viability after 12 days	GATGTGGAGGTTTCTGCCAGTGG	RIOK2	ENSG00000058729	-0.09786587064243135	[137]	[1,37,119]	-1	hSpCas9	negative selection	1570681
97171363	97171386	5	+	26627737	HeLa	viability after 12 days	CTGATGCAGGATCTTCAACATGG	RIOK2	ENSG00000058729	-0.021535192303875794	[1185]	[407,486,550]	0	hSpCas9	negative selection	1570682
97177822	97177845	5	+	26627737	HeLa	viability after 12 days	CATTTGTCAACCGATAGCCCTGG	RIOK2	ENSG00000058729	-5.682149930071927	[204]	[0,0,2]	-9	hSpCas9	negative selection	1570683
97179113	97179136	5	+	26627737	HeLa	viability after 12 days	ACAGCCACCATGTTTAAGGCTGG	RIOK2	ENSG00000058729	-0.49654405080664854	[172]	[49,12,92]	-4	hSpCas9	negative selection	1570684
97183095	97183118	5	+	26627737	HeLa	viability after 12 days	GAAGGGAGAACAGGAACGGCGGG	RIOK2	ENSG00000058729	-1.1004460055536078	[189]	[12,75,15]	-7	hSpCas9	negative selection	1570685
97167953	97167976	5	-	26627737	HeLa	viability after 15 days	GATGTGGAGGTTTCTGCCAGTGG	RIOK2	ENSG00000058729	-3.5811864123074644	[137]	[0,9,2]	-9	hSpCas9	negative selection	1652996
97171363	97171386	5	+	26627737	HeLa	viability after 15 days	CTGATGCAGGATCTTCAACATGG	RIOK2	ENSG00000058729	-0.23219229990607015	[1185]	[420,376,436]	-2	hSpCas9	negative selection	1652997
97177822	97177845	5	+	26627737	HeLa	viability after 15 days	CATTTGTCAACCGATAGCCCTGG	RIOK2	ENSG00000058729	-3.1690331645978627	[204]	[24,0,0]	-9	hSpCas9	negative selection	1652998
97179113	97179136	5	+	26627737	HeLa	viability after 15 days	ACAGCCACCATGTTTAAGGCTGG	RIOK2	ENSG00000058729	0.21471724994171681	[172]	[152,36,51]	1	hSpCas9	negative selection	1652999
97183095	97183118	5	+	26627737	HeLa	viability after 15 days	GAAGGGAGAACAGGAACGGCGGG	RIOK2	ENSG00000058729	-1.107061320970382	[189]	[63,35,4]	-7	hSpCas9	negative selection	1653000
97167953	97167976	5	-	26627737	HeLa	viability after 18 days	GATGTGGAGGTTTCTGCCAGTGG	RIOK2	ENSG00000058729	-3.3342084462304076	[137]	[0,9,2]	-9	hSpCas9	negative selection	1735311
97171363	97171386	5	+	26627737	HeLa	viability after 18 days	CTGATGCAGGATCTTCAACATGG	RIOK2	ENSG00000058729	-0.272463425696708	[1185]	[258,313,436]	-2	hSpCas9	negative selection	1735312
97177822	97177845	5	+	26627737	HeLa	viability after 18 days	CATTTGTCAACCGATAGCCCTGG	RIOK2	ENSG00000058729	-3.3061720283324703	[204]	[14,0,0]	-9	hSpCas9	negative selection	1735313
97179113	97179136	5	+	26627737	HeLa	viability after 18 days	ACAGCCACCATGTTTAAGGCTGG	RIOK2	ENSG00000058729	0.1967502253327187	[172]	[101,28,51]	1	hSpCas9	negative selection	1735314
97183095	97183118	5	+	26627737	HeLa	viability after 18 days	GAAGGGAGAACAGGAACGGCGGG	RIOK2	ENSG00000058729	-1.2454571376389183	[189]	[37,27,4]	-8	hSpCas9	negative selection	1735315
97167953	97167976	5	-	26627737	HCT116	viability after 6 days	GATGTGGAGGTTTCTGCCAGTGG	RIOK2	ENSG00000058729	-1.846490263651008	[370]	[41,1]	-8	hSpCas9	negative selection	1817626
97171363	97171386	5	+	26627737	HCT116	viability after 6 days	CTGATGCAGGATCTTCAACATGG	RIOK2	ENSG00000058729	-0.0407512513216306	[1842]	[572,120]	0	hSpCas9	negative selection	1817627
97177822	97177845	5	+	26627737	HCT116	viability after 6 days	CATTTGTCAACCGATAGCCCTGG	RIOK2	ENSG00000058729	0.21536559991872262	[492]	[205,25]	1	hSpCas9	negative selection	1817628
97179113	97179136	5	+	26627737	HCT116	viability after 6 days	ACAGCCACCATGTTTAAGGCTGG	RIOK2	ENSG00000058729	-1.1371004740884143	[549]	[28,44]	-6	hSpCas9	negative selection	1817629
97183095	97183118	5	+	26627737	HCT116	viability after 6 days	GAAGGGAGAACAGGAACGGCGGG	RIOK2	ENSG00000058729	-2.061135139908576	[252]	[24,0]	-8	hSpCas9	negative selection	1817630
97167953	97167976	5	-	26627737	HCT116	viability after 8 days	GATGTGGAGGTTTCTGCCAGTGG	RIOK2	ENSG00000058729	-1.7293349669520697	[226]	[62,43,6]	-9	hSpCas9	negative selection	1899941
97171363	97171386	5	+	26627737	HCT116	viability after 8 days	CTGATGCAGGATCTTCAACATGG	RIOK2	ENSG00000058729	-0.8518300372655817	[1003]	[383,313,223]	-8	hSpCas9	negative selection	1899942
97177822	97177845	5	+	26627737	HCT116	viability after 8 days	CATTTGTCAACCGATAGCCCTGG	RIOK2	ENSG00000058729	0.9410508749347832	[55]	[37,50,87]	8	hSpCas9	negative selection	1899943
97179113	97179136	5	+	26627737	HCT116	viability after 8 days	ACAGCCACCATGTTTAAGGCTGG	RIOK2	ENSG00000058729	-1.7919019485834526	[560]	[67,73,124]	-9	hSpCas9	negative selection	1899944
97183095	97183118	5	+	26627737	HCT116	viability after 8 days	GAAGGGAGAACAGGAACGGCGGG	RIOK2	ENSG00000058729	0.3203277565668854	[42]	[33,38,15]	3	hSpCas9	negative selection	1899945
97167953	97167976	5	-	26627737	HCT116	viability after 9 days	GATGTGGAGGTTTCTGCCAGTGG	RIOK2	ENSG00000058729	-0.7403911204930915	[370]	[127,4]	-5	hSpCas9	negative selection	1982256
97171363	97171386	5	+	26627737	HCT116	viability after 9 days	CTGATGCAGGATCTTCAACATGG	RIOK2	ENSG00000058729	-0.5765677161830547	[1842]	[372,295]	-4	hSpCas9	negative selection	1982257
97177822	97177845	5	+	26627737	HCT116	viability after 9 days	CATTTGTCAACCGATAGCCCTGG	RIOK2	ENSG00000058729	-2.214191849239139	[492]	[0,49]	-9	hSpCas9	negative selection	1982258
97179113	97179136	5	+	26627737	HCT116	viability after 9 days	ACAGCCACCATGTTTAAGGCTGG	RIOK2	ENSG00000058729	1.316584842694737	[549]	[238,465]	8	hSpCas9	negative selection	1982259
97183095	97183118	5	+	26627737	HCT116	viability after 9 days	GAAGGGAGAACAGGAACGGCGGG	RIOK2	ENSG00000058729	-2.2457979773325767	[252]	[30,0]	-9	hSpCas9	negative selection	1982260
97167953	97167976	5	-	26627737	HCT116	viability after 12 days	GATGTGGAGGTTTCTGCCAGTGG	RIOK2	ENSG00000058729	-3.5974377367748436	[226]	[7,20,0]	-9	hSpCas9	negative selection	2064571
97171363	97171386	5	+	26627737	HCT116	viability after 12 days	CTGATGCAGGATCTTCAACATGG	RIOK2	ENSG00000058729	-1.1948744480590294	[1003]	[282,154,246]	-8	hSpCas9	negative selection	2064572
97177822	97177845	5	+	26627737	HCT116	viability after 12 days	CATTTGTCAACCGATAGCCCTGG	RIOK2	ENSG00000058729	0.7540147593259388	[55]	[37,52,58]	6	hSpCas9	negative selection	2064573
97179113	97179136	5	+	26627737	HCT116	viability after 12 days	ACAGCCACCATGTTTAAGGCTGG	RIOK2	ENSG00000058729	-2.132725165446688	[560]	[37,56,108]	-9	hSpCas9	negative selection	2064574
97183095	97183118	5	+	26627737	HCT116	viability after 12 days	GAAGGGAGAACAGGAACGGCGGG	RIOK2	ENSG00000058729	0.7917828376847971	[42]	[65,38,9]	7	hSpCas9	negative selection	2064575
97167953	97167976	5	-	26627737	HCT116	viability after 15 days	GATGTGGAGGTTTCTGCCAGTGG	RIOK2	ENSG00000058729	-2.5995141731596862	[226]	[8,31,21]	-9	hSpCas9	negative selection	2146886
97171363	97171386	5	+	26627737	HCT116	viability after 15 days	CTGATGCAGGATCTTCAACATGG	RIOK2	ENSG00000058729	-1.7395832578147068	[1003]	[189,148,180]	-9	hSpCas9	negative selection	2146887
97177822	97177845	5	+	26627737	HCT116	viability after 15 days	CATTTGTCAACCGATAGCCCTGG	RIOK2	ENSG00000058729	-0.26592538614177075	[55]	[25,14,38]	-3	hSpCas9	negative selection	2146888
97179113	97179136	5	+	26627737	HCT116	viability after 15 days	ACAGCCACCATGTTTAAGGCTGG	RIOK2	ENSG00000058729	-2.45279145854498	[560]	[60,72,42]	-9	hSpCas9	negative selection	2146889
97183095	97183118	5	+	26627737	HCT116	viability after 15 days	GAAGGGAGAACAGGAACGGCGGG	RIOK2	ENSG00000058729	0.8881980514077772	[42]	[65,61,11]	7	hSpCas9	negative selection	2146890
97167953	97167976	5	-	26627737	HCT116	viability after 18 days	GATGTGGAGGTTTCTGCCAGTGG	RIOK2	ENSG00000058729	-2.5453266263917405	[226]	[1,11,43]	-9	hSpCas9	negative selection	2229201
97171363	97171386	5	+	26627737	HCT116	viability after 18 days	CTGATGCAGGATCTTCAACATGG	RIOK2	ENSG00000058729	-2.504307896352826	[1003]	[86,21,154]	-9	hSpCas9	negative selection	2229202
97177822	97177845	5	+	26627737	HCT116	viability after 18 days	CATTTGTCAACCGATAGCCCTGG	RIOK2	ENSG00000058729	-0.10233348558182609	[55]	[12,52,6]	-1	hSpCas9	negative selection	2229203
97179113	97179136	5	+	26627737	HCT116	viability after 18 days	ACAGCCACCATGTTTAAGGCTGG	RIOK2	ENSG00000058729	-2.797187839712193	[560]	[7,17,94]	-9	hSpCas9	negative selection	2229204
97183095	97183118	5	+	26627737	HCT116	viability after 18 days	GAAGGGAGAACAGGAACGGCGGG	RIOK2	ENSG00000058729	1.2032961622738485	[42]	[33,92,11]	8	hSpCas9	negative selection	2229205
97179109	97179132	5	+	24336569	HL60	viability	TATTACAGCCACCATGTTTAAGG	RIOK2	ENSG00000058729	0.2133814873579597	[612]	[1503]	2	hSpCas9	negative selection	2289685
97179117	97179140	5	-	24336569	HL60	viability	ATAGCCAGCCTTAAACATGGTGG	RIOK2	ENSG00000058729	-1.8958480014671175	[822]	[467]	-9	hSpCas9	negative selection	2289686
97179137	97179160	5	+	24336569	HL60	viability	TATAGAAGCAATCAAACTGCCGG	RIOK2	ENSG00000058729	-0.7424913091098333	[588]	[744]	-6	hSpCas9	negative selection	2289687
97179151	97179174	5	+	24336569	HL60	viability	AACTGCCGGGAACAATTTCATGG	RIOK2	ENSG00000058729	1.4857963983588007	[40]	[242]	8	hSpCas9	negative selection	2289688
97179156	97179179	5	-	24336569	HL60	viability	AAGAACCATGAAATTGTTCCCGG	RIOK2	ENSG00000058729	-0.3543226244146582	[1502]	[2487]	-3	hSpCas9	negative selection	2289689
97179183	97179206	5	-	24336569	HL60	viability	CTTTAATTTCAGGTTGAAATGGG	RIOK2	ENSG00000058729	2.2745897781630924	[187]	[1924]	9	hSpCas9	negative selection	2289690
97183125	97183148	5	-	24336569	HL60	viability	TGACTTCAGGGTCTTGACCGCGG	RIOK2	ENSG00000058729	-5.609201732657102	[345]	[14]	-9	hSpCas9	negative selection	2289691
97183131	97183154	5	+	24336569	HL60	viability	TCAAGACCCTGAAGTCATCTCGG	RIOK2	ENSG00000058729	-0.2936403209248595	[1242]	[2145]	-3	hSpCas9	negative selection	2289692
97183137	97183160	5	-	24336569	HL60	viability	CATGAGCCGAGATGACTTCAGGG	RIOK2	ENSG00000058729	-1.3417356041674624	[938]	[783]	-8	hSpCas9	negative selection	2289693
97183150	97183173	5	+	24336569	HL60	viability	TCGGCTCATGTAACGCAACTTGG	RIOK2	ENSG00000058729	0.07392330275466463	[808]	[1801]	0	hSpCas9	negative selection	2289694
97179109	97179132	5	+	24336569	KBM7	viability	TATTACAGCCACCATGTTTAAGG	RIOK2	ENSG00000058729	0.7710227524952906	[734]	[3420]	7	hSpCas9	negative selection	2356862
97179117	97179140	5	-	24336569	KBM7	viability	ATAGCCAGCCTTAAACATGGTGG	RIOK2	ENSG00000058729	-2.2147450284907877	[1061]	[623]	-8	hSpCas9	negative selection	2356863
97179137	97179160	5	+	24336569	KBM7	viability	TATAGAAGCAATCAAACTGCCGG	RIOK2	ENSG00000058729	-0.17614590726941776	[470]	[1136]	-1	hSpCas9	negative selection	2356864
97179151	97179174	5	+	24336569	KBM7	viability	AACTGCCGGGAACAATTTCATGG	RIOK2	ENSG00000058729	0.6064156930918467	[176]	[734]	5	hSpCas9	negative selection	2356865
97179156	97179179	5	-	24336569	KBM7	viability	AAGAACCATGAAATTGTTCCCGG	RIOK2	ENSG00000058729	-0.21811559310683748	[1162]	[2726]	-2	hSpCas9	negative selection	2356866
97179183	97179206	5	-	24336569	KBM7	viability	CTTTAATTTCAGGTTGAAATGGG	RIOK2	ENSG00000058729	0.398860564640773	[514]	[1851]	3	hSpCas9	negative selection	2356867
97183125	97183148	5	-	24336569	KBM7	viability	TGACTTCAGGGTCTTGACCGCGG	RIOK2	ENSG00000058729	-3.3132781048372912	[491]	[134]	-9	hSpCas9	negative selection	2356868
97183131	97183154	5	+	24336569	KBM7	viability	TCAAGACCCTGAAGTCATCTCGG	RIOK2	ENSG00000058729	-0.1521233130227111	[1198]	[2942]	-1	hSpCas9	negative selection	2356869
97183137	97183160	5	-	24336569	KBM7	viability	CATGAGCCGAGATGACTTCAGGG	RIOK2	ENSG00000058729	-2.401130273861959	[977]	[504]	-8	hSpCas9	negative selection	2356870
97183150	97183173	5	+	24336569	KBM7	viability	TCGGCTCATGTAACGCAACTTGG	RIOK2	ENSG00000058729	-0.09514323683466441	[626]	[1600]	-1	hSpCas9	negative selection	2356871
97179151	97179174	5	+	27260157	DLD1	viability	AACTGCCGGGAACAATTTCATGG	RIOK2	ENSG00000058729	-0.968707438958555	[]	[]	-7	hSpCas9	negative selection	2574117
97177735	97177758	5	+	27260157	DLD1	viability	ATTCTTTGCCAACACCCATCTGG	RIOK2	ENSG00000058729	-2.49565914821048	[]	[]	-9	hSpCas9	negative selection	2577197
97179183	97179206	5	-	27260157	DLD1	viability	CTTTAATTTCAGGTTGAAATGGG	RIOK2	ENSG00000058729	-0.317853980376456	[]	[]	-3	hSpCas9	negative selection	2586038
97171363	97171386	5	+	27260157	DLD1	viability	CTGATGCAGGATCTTCAACATGG	RIOK2	ENSG00000058729	-2.40118543009822	[]	[]	-9	hSpCas9	negative selection	2587277
97177761	97177784	5	-	27260157	DLD1	viability	AGGCAAGTAGTTGAGTCTGTTGG	RIOK2	ENSG00000058729	-0.971938801780653	[]	[]	-7	hSpCas9	negative selection	2604529
97177818	97177841	5	-	27260157	DLD1	viability	GGCTATCGGTTGACAAATGCAGG	RIOK2	ENSG00000058729	-0.365646376155361	[]	[]	-3	hSpCas9	negative selection	2606441
97173197	97173220	5	-	27260157	DLD1	viability	CAATCGTCATGCAGTGGTCATGG	RIOK2	ENSG00000058729	-0.534076448397993	[]	[]	-4	hSpCas9	negative selection	2607140
97179113	97179136	5	+	27260157	DLD1	viability	ACAGCCACCATGTTTAAGGCTGG	RIOK2	ENSG00000058729	-1.5351377069903	[]	[]	-8	hSpCas9	negative selection	2609496
97183131	97183154	5	+	27260157	DLD1	viability	TCAAGACCCTGAAGTCATCTCGG	RIOK2	ENSG00000058729	-1.99501633978438	[]	[]	-8	hSpCas9	negative selection	2613357
97177822	97177845	5	+	27260157	DLD1	viability	CATTTGTCAACCGATAGCCCTGG	RIOK2	ENSG00000058729	-1.19465252156175	[]	[]	-7	hSpCas9	negative selection	2614328
97183137	97183160	5	-	27260157	DLD1	viability	CATGAGCCGAGATGACTTCAGGG	RIOK2	ENSG00000058729	-3.47107049092199	[]	[]	-9	hSpCas9	negative selection	2616959
97179156	97179179	5	-	27260157	DLD1	viability	AAGAACCATGAAATTGTTCCCGG	RIOK2	ENSG00000058729	-2.13786178674498	[]	[]	-9	hSpCas9	negative selection	2617668
97179109	97179132	5	+	27260157	DLD1	viability	TATTACAGCCACCATGTTTAAGG	RIOK2	ENSG00000058729	-2.70678647155937	[]	[]	-9	hSpCas9	negative selection	2618589
97183150	97183173	5	+	27260157	DLD1	viability	TCGGCTCATGTAACGCAACTTGG	RIOK2	ENSG00000058729	-3.43394813312408	[]	[]	-9	hSpCas9	negative selection	2620160
97177743	97177766	5	-	27260157	DLD1	viability	GTTGGAAACCAGATGGGTGTTGG	RIOK2	ENSG00000058729	-4.28108860752039	[]	[]	-9	hSpCas9	negative selection	2621771
97179117	97179140	5	-	27260157	DLD1	viability	ATAGCCAGCCTTAAACATGGTGG	RIOK2	ENSG00000058729	-2.62168031858918	[]	[]	-9	hSpCas9	negative selection	2642521
97177133	97177156	5	-	27260157	DLD1	viability	ATCTCGTCTCTCTGCCATGAAGG	RIOK2	ENSG00000058729	-0.137623114438077	[]	[]	-1	hSpCas9	negative selection	2643666
97183125	97183148	5	-	27260157	DLD1	viability	TGACTTCAGGGTCTTGACCGCGG	RIOK2	ENSG00000058729	-3.82175352884072	[]	[]	-9	hSpCas9	negative selection	2646541
97177832	97177855	5	-	27260157	DLD1	viability	GTCTAGCTGTCCAGGGCTATCGG	RIOK2	ENSG00000058729	-0.561164176357463	[]	[]	-4	hSpCas9	negative selection	2646719
97179137	97179160	5	+	27260157	DLD1	viability	TATAGAAGCAATCAAACTGCCGG	RIOK2	ENSG00000058729	-2.605403065099	[]	[]	-9	hSpCas9	negative selection	2647499
97179151	97179174	5	+	27260157	HT1080	viability	AACTGCCGGGAACAATTTCATGG	RIOK2	ENSG00000058729	-1.07561442916681	[]	[]	-8	hSpCas9	negative selection	2650247
97177735	97177758	5	+	27260157	HT1080	viability	ATTCTTTGCCAACACCCATCTGG	RIOK2	ENSG00000058729	-2.07418855370008	[]	[]	-9	hSpCas9	negative selection	2653327
97179183	97179206	5	-	27260157	HT1080	viability	CTTTAATTTCAGGTTGAAATGGG	RIOK2	ENSG00000058729	0.411872135909295	[]	[]	4	hSpCas9	negative selection	2662168
97171363	97171386	5	+	27260157	HT1080	viability	CTGATGCAGGATCTTCAACATGG	RIOK2	ENSG00000058729	-1.78298066595559	[]	[]	-9	hSpCas9	negative selection	2663407
97177761	97177784	5	-	27260157	HT1080	viability	AGGCAAGTAGTTGAGTCTGTTGG	RIOK2	ENSG00000058729	0.412070363113951	[]	[]	4	hSpCas9	negative selection	2680659
97177818	97177841	5	-	27260157	HT1080	viability	GGCTATCGGTTGACAAATGCAGG	RIOK2	ENSG00000058729	-2.41975156734941	[]	[]	-9	hSpCas9	negative selection	2682571
97173197	97173220	5	-	27260157	HT1080	viability	CAATCGTCATGCAGTGGTCATGG	RIOK2	ENSG00000058729	-1.76190501376715	[]	[]	-9	hSpCas9	negative selection	2683270
97179113	97179136	5	+	27260157	HT1080	viability	ACAGCCACCATGTTTAAGGCTGG	RIOK2	ENSG00000058729	-1.66665913841094	[]	[]	-9	hSpCas9	negative selection	2685626
97183131	97183154	5	+	27260157	HT1080	viability	TCAAGACCCTGAAGTCATCTCGG	RIOK2	ENSG00000058729	-0.452723550172287	[]	[]	-7	hSpCas9	negative selection	2689487
97177822	97177845	5	+	27260157	HT1080	viability	CATTTGTCAACCGATAGCCCTGG	RIOK2	ENSG00000058729	-1.12558228147561	[]	[]	-8	hSpCas9	negative selection	2690458
97183137	97183160	5	-	27260157	HT1080	viability	CATGAGCCGAGATGACTTCAGGG	RIOK2	ENSG00000058729	-2.14127541526814	[]	[]	-9	hSpCas9	negative selection	2693089
97179156	97179179	5	-	27260157	HT1080	viability	AAGAACCATGAAATTGTTCCCGG	RIOK2	ENSG00000058729	-1.12189295014871	[]	[]	-8	hSpCas9	negative selection	2693798
97179109	97179132	5	+	27260157	HT1080	viability	TATTACAGCCACCATGTTTAAGG	RIOK2	ENSG00000058729	-2.18677073268247	[]	[]	-9	hSpCas9	negative selection	2694719
97183150	97183173	5	+	27260157	HT1080	viability	TCGGCTCATGTAACGCAACTTGG	RIOK2	ENSG00000058729	-2.38820159769082	[]	[]	-9	hSpCas9	negative selection	2696290
97177743	97177766	5	-	27260157	HT1080	viability	GTTGGAAACCAGATGGGTGTTGG	RIOK2	ENSG00000058729	-2.20448505830973	[]	[]	-9	hSpCas9	negative selection	2697901
97179117	97179140	5	-	27260157	HT1080	viability	ATAGCCAGCCTTAAACATGGTGG	RIOK2	ENSG00000058729	-2.22384344814566	[]	[]	-9	hSpCas9	negative selection	2718651
97177133	97177156	5	-	27260157	HT1080	viability	ATCTCGTCTCTCTGCCATGAAGG	RIOK2	ENSG00000058729	-0.0426590317442447	[]	[]	0	hSpCas9	negative selection	2719796
97183125	97183148	5	-	27260157	HT1080	viability	TGACTTCAGGGTCTTGACCGCGG	RIOK2	ENSG00000058729	-2.3080441126792	[]	[]	-9	hSpCas9	negative selection	2722671
97177832	97177855	5	-	27260157	HT1080	viability	GTCTAGCTGTCCAGGGCTATCGG	RIOK2	ENSG00000058729	-2.47267203499523	[]	[]	-9	hSpCas9	negative selection	2722849
97179137	97179160	5	+	27260157	HT1080	viability	TATAGAAGCAATCAAACTGCCGG	RIOK2	ENSG00000058729	-1.99652240126593	[]	[]	-9	hSpCas9	negative selection	2723629
97179151	97179174	5	+	27260157	MKN45	viability	AACTGCCGGGAACAATTTCATGG	RIOK2	ENSG00000058729	-0.080381428633332	[]	[]	0	hSpCas9	negative selection	2726377
97177735	97177758	5	+	27260157	MKN45	viability	ATTCTTTGCCAACACCCATCTGG	RIOK2	ENSG00000058729	-1.28141307172008	[]	[]	-8	hSpCas9	negative selection	2729457
97179183	97179206	5	-	27260157	MKN45	viability	CTTTAATTTCAGGTTGAAATGGG	RIOK2	ENSG00000058729	0.127262068890738	[]	[]	4	hSpCas9	negative selection	2738298
97171363	97171386	5	+	27260157	MKN45	viability	CTGATGCAGGATCTTCAACATGG	RIOK2	ENSG00000058729	-0.621564406114695	[]	[]	-6	hSpCas9	negative selection	2739537
97177761	97177784	5	-	27260157	MKN45	viability	AGGCAAGTAGTTGAGTCTGTTGG	RIOK2	ENSG00000058729	0.186096532617804	[]	[]	5	hSpCas9	negative selection	2756789
97177818	97177841	5	-	27260157	MKN45	viability	GGCTATCGGTTGACAAATGCAGG	RIOK2	ENSG00000058729	-0.576128556576294	[]	[]	-6	hSpCas9	negative selection	2758701
97173197	97173220	5	-	27260157	MKN45	viability	CAATCGTCATGCAGTGGTCATGG	RIOK2	ENSG00000058729	-0.77619707608299	[]	[]	-7	hSpCas9	negative selection	2759400
97179113	97179136	5	+	27260157	MKN45	viability	ACAGCCACCATGTTTAAGGCTGG	RIOK2	ENSG00000058729	0.0145743961608758	[]	[]	0	hSpCas9	negative selection	2761756
97183131	97183154	5	+	27260157	MKN45	viability	TCAAGACCCTGAAGTCATCTCGG	RIOK2	ENSG00000058729	-0.419676362063781	[]	[]	-6	hSpCas9	negative selection	2765617
97177822	97177845	5	+	27260157	MKN45	viability	CATTTGTCAACCGATAGCCCTGG	RIOK2	ENSG00000058729	-0.786171007453474	[]	[]	-7	hSpCas9	negative selection	2766588
97183137	97183160	5	-	27260157	MKN45	viability	CATGAGCCGAGATGACTTCAGGG	RIOK2	ENSG00000058729	-1.13614867430882	[]	[]	-8	hSpCas9	negative selection	2769219
97179156	97179179	5	-	27260157	MKN45	viability	AAGAACCATGAAATTGTTCCCGG	RIOK2	ENSG00000058729	-0.671016804125452	[]	[]	-7	hSpCas9	negative selection	2769928
97179109	97179132	5	+	27260157	MKN45	viability	TATTACAGCCACCATGTTTAAGG	RIOK2	ENSG00000058729	-0.24626580734507	[]	[]	-1	hSpCas9	negative selection	2770849
97183150	97183173	5	+	27260157	MKN45	viability	TCGGCTCATGTAACGCAACTTGG	RIOK2	ENSG00000058729	-1.41411484562728	[]	[]	-8	hSpCas9	negative selection	2772420
97177743	97177766	5	-	27260157	MKN45	viability	GTTGGAAACCAGATGGGTGTTGG	RIOK2	ENSG00000058729	-2.71027524597982	[]	[]	-9	hSpCas9	negative selection	2774031
97179117	97179140	5	-	27260157	MKN45	viability	ATAGCCAGCCTTAAACATGGTGG	RIOK2	ENSG00000058729	-1.69579279781638	[]	[]	-9	hSpCas9	negative selection	2794781
97177133	97177156	5	-	27260157	MKN45	viability	ATCTCGTCTCTCTGCCATGAAGG	RIOK2	ENSG00000058729	0.78634108057276	[]	[]	7	hSpCas9	negative selection	2795926
97183125	97183148	5	-	27260157	MKN45	viability	TGACTTCAGGGTCTTGACCGCGG	RIOK2	ENSG00000058729	-2.84863600168589	[]	[]	-9	hSpCas9	negative selection	2798801
97177832	97177855	5	-	27260157	MKN45	viability	GTCTAGCTGTCCAGGGCTATCGG	RIOK2	ENSG00000058729	-1.56061542298979	[]	[]	-9	hSpCas9	negative selection	2798979
97179137	97179160	5	+	27260157	MKN45	viability	TATAGAAGCAATCAAACTGCCGG	RIOK2	ENSG00000058729	-1.74406697281277	[]	[]	-9	hSpCas9	negative selection	2799759
97179151	97179174	5	+	27260157	RKO	viability	AACTGCCGGGAACAATTTCATGG	RIOK2	ENSG00000058729	-0.955634744052682	[]	[]	-8	hSpCas9	negative selection	2802507
97177735	97177758	5	+	27260157	RKO	viability	ATTCTTTGCCAACACCCATCTGG	RIOK2	ENSG00000058729	-2.86425091449075	[]	[]	-9	hSpCas9	negative selection	2805587
97179183	97179206	5	-	27260157	RKO	viability	CTTTAATTTCAGGTTGAAATGGG	RIOK2	ENSG00000058729	0.198830338870323	[]	[]	1	hSpCas9	negative selection	2814428
97171363	97171386	5	+	27260157	RKO	viability	CTGATGCAGGATCTTCAACATGG	RIOK2	ENSG00000058729	-1.74548150492458	[]	[]	-9	hSpCas9	negative selection	2815667
97177761	97177784	5	-	27260157	RKO	viability	AGGCAAGTAGTTGAGTCTGTTGG	RIOK2	ENSG00000058729	-1.65082421381478	[]	[]	-9	hSpCas9	negative selection	2832919
97177818	97177841	5	-	27260157	RKO	viability	GGCTATCGGTTGACAAATGCAGG	RIOK2	ENSG00000058729	-2.34851635284756	[]	[]	-9	hSpCas9	negative selection	2834831
97173197	97173220	5	-	27260157	RKO	viability	CAATCGTCATGCAGTGGTCATGG	RIOK2	ENSG00000058729	-1.3245261190489	[]	[]	-8	hSpCas9	negative selection	2835530
97179113	97179136	5	+	27260157	RKO	viability	ACAGCCACCATGTTTAAGGCTGG	RIOK2	ENSG00000058729	-0.966470372535179	[]	[]	-8	hSpCas9	negative selection	2837886
97183131	97183154	5	+	27260157	RKO	viability	TCAAGACCCTGAAGTCATCTCGG	RIOK2	ENSG00000058729	-1.40274220427522	[]	[]	-8	hSpCas9	negative selection	2841747
97177822	97177845	5	+	27260157	RKO	viability	CATTTGTCAACCGATAGCCCTGG	RIOK2	ENSG00000058729	-1.96538723981242	[]	[]	-9	hSpCas9	negative selection	2842718
97183137	97183160	5	-	27260157	RKO	viability	CATGAGCCGAGATGACTTCAGGG	RIOK2	ENSG00000058729	-2.1423874818574	[]	[]	-9	hSpCas9	negative selection	2845349
97179156	97179179	5	-	27260157	RKO	viability	AAGAACCATGAAATTGTTCCCGG	RIOK2	ENSG00000058729	-1.83398001880612	[]	[]	-9	hSpCas9	negative selection	2846058
97179109	97179132	5	+	27260157	RKO	viability	TATTACAGCCACCATGTTTAAGG	RIOK2	ENSG00000058729	-1.30818426013019	[]	[]	-8	hSpCas9	negative selection	2846979
97183150	97183173	5	+	27260157	RKO	viability	TCGGCTCATGTAACGCAACTTGG	RIOK2	ENSG00000058729	-1.5549877288261	[]	[]	-9	hSpCas9	negative selection	2848550
97177743	97177766	5	-	27260157	RKO	viability	GTTGGAAACCAGATGGGTGTTGG	RIOK2	ENSG00000058729	-3.02563513281989	[]	[]	-9	hSpCas9	negative selection	2850161
97179117	97179140	5	-	27260157	RKO	viability	ATAGCCAGCCTTAAACATGGTGG	RIOK2	ENSG00000058729	-2.35662653270614	[]	[]	-9	hSpCas9	negative selection	2870911
97177133	97177156	5	-	27260157	RKO	viability	ATCTCGTCTCTCTGCCATGAAGG	RIOK2	ENSG00000058729	-0.727762577923672	[]	[]	-7	hSpCas9	negative selection	2872056
97183125	97183148	5	-	27260157	RKO	viability	TGACTTCAGGGTCTTGACCGCGG	RIOK2	ENSG00000058729	-3.16512506531626	[]	[]	-9	hSpCas9	negative selection	2874931
97177832	97177855	5	-	27260157	RKO	viability	GTCTAGCTGTCCAGGGCTATCGG	RIOK2	ENSG00000058729	-2.52362641648812	[]	[]	-9	hSpCas9	negative selection	2875109
97179137	97179160	5	+	27260157	RKO	viability	TATAGAAGCAATCAAACTGCCGG	RIOK2	ENSG00000058729	-1.32777960520082	[]	[]	-8	hSpCas9	negative selection	2875889
97179151	97179174	5	+	27260157	SF268	viability	AACTGCCGGGAACAATTTCATGG	RIOK2	ENSG00000058729	-1.6630316934276	[]	[]	-8	hSpCas9	negative selection	2878637
97177735	97177758	5	+	27260157	SF268	viability	ATTCTTTGCCAACACCCATCTGG	RIOK2	ENSG00000058729	-3.31660798942184	[]	[]	-9	hSpCas9	negative selection	2881717
97179183	97179206	5	-	27260157	SF268	viability	CTTTAATTTCAGGTTGAAATGGG	RIOK2	ENSG00000058729	0.573441893273505	[]	[]	8	hSpCas9	negative selection	2890558
97171363	97171386	5	+	27260157	SF268	viability	CTGATGCAGGATCTTCAACATGG	RIOK2	ENSG00000058729	-1.78256962079736	[]	[]	-8	hSpCas9	negative selection	2891797
97177761	97177784	5	-	27260157	SF268	viability	AGGCAAGTAGTTGAGTCTGTTGG	RIOK2	ENSG00000058729	-3.1815483085101	[]	[]	-9	hSpCas9	negative selection	2909049
97177818	97177841	5	-	27260157	SF268	viability	GGCTATCGGTTGACAAATGCAGG	RIOK2	ENSG00000058729	-1.59719051109778	[]	[]	-8	hSpCas9	negative selection	2910961
97173197	97173220	5	-	27260157	SF268	viability	CAATCGTCATGCAGTGGTCATGG	RIOK2	ENSG00000058729	-1.43810924917953	[]	[]	-8	hSpCas9	negative selection	2911660
97179113	97179136	5	+	27260157	SF268	viability	ACAGCCACCATGTTTAAGGCTGG	RIOK2	ENSG00000058729	-1.09733202087758	[]	[]	-7	hSpCas9	negative selection	2914016
97183131	97183154	5	+	27260157	SF268	viability	TCAAGACCCTGAAGTCATCTCGG	RIOK2	ENSG00000058729	-1.79531005114564	[]	[]	-8	hSpCas9	negative selection	2917877
97177822	97177845	5	+	27260157	SF268	viability	CATTTGTCAACCGATAGCCCTGG	RIOK2	ENSG00000058729	-2.23898365663987	[]	[]	-9	hSpCas9	negative selection	2918848
97183137	97183160	5	-	27260157	SF268	viability	CATGAGCCGAGATGACTTCAGGG	RIOK2	ENSG00000058729	-2.20012455889245	[]	[]	-9	hSpCas9	negative selection	2921479
97179156	97179179	5	-	27260157	SF268	viability	AAGAACCATGAAATTGTTCCCGG	RIOK2	ENSG00000058729	-1.511370501551	[]	[]	-8	hSpCas9	negative selection	2922188
97179109	97179132	5	+	27260157	SF268	viability	TATTACAGCCACCATGTTTAAGG	RIOK2	ENSG00000058729	-1.51242911250013	[]	[]	-8	hSpCas9	negative selection	2923109
97183150	97183173	5	+	27260157	SF268	viability	TCGGCTCATGTAACGCAACTTGG	RIOK2	ENSG00000058729	-1.72311303906016	[]	[]	-8	hSpCas9	negative selection	2924680
97177743	97177766	5	-	27260157	SF268	viability	GTTGGAAACCAGATGGGTGTTGG	RIOK2	ENSG00000058729	-2.54174313826941	[]	[]	-9	hSpCas9	negative selection	2926291
97179117	97179140	5	-	27260157	SF268	viability	ATAGCCAGCCTTAAACATGGTGG	RIOK2	ENSG00000058729	-2.2787291549741	[]	[]	-9	hSpCas9	negative selection	2947041
97177133	97177156	5	-	27260157	SF268	viability	ATCTCGTCTCTCTGCCATGAAGG	RIOK2	ENSG00000058729	-1.72112938319742	[]	[]	-8	hSpCas9	negative selection	2948186
97183125	97183148	5	-	27260157	SF268	viability	TGACTTCAGGGTCTTGACCGCGG	RIOK2	ENSG00000058729	-3.95317381932468	[]	[]	-9	hSpCas9	negative selection	2951061
97177832	97177855	5	-	27260157	SF268	viability	GTCTAGCTGTCCAGGGCTATCGG	RIOK2	ENSG00000058729	-1.64769126723815	[]	[]	-8	hSpCas9	negative selection	2951239
97179137	97179160	5	+	27260157	SF268	viability	TATAGAAGCAATCAAACTGCCGG	RIOK2	ENSG00000058729	-2.45087848432097	[]	[]	-9	hSpCas9	negative selection	2952019
97179117	97179140	5	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	ATAGCCAGCCTTAAACATGGTGG	RIOK2	ENSG00000058729	-0.8969633252672369	[3,2]	[1,0]	-8	hSpCas9	positive selection	3016932
97173209	97173232	5	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCATGACGATTGTAATCAATTGG	RIOK2	ENSG00000058729	0.4238425289300729	[5,5]	[4,7]	8	hSpCas9	positive selection	3016933
97183125	97183148	5	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TGACTTCAGGGTCTTGACCGCGG	RIOK2	ENSG00000058729	-0.6267019588721918	[2,2]	[0,1]	-7	hSpCas9	positive selection	3016934
97177750	97177773	5	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TGAGTCTGTTGGAAACCAGATGG	RIOK2	ENSG00000058729	-0.856374514386387	[2,2]	[0,0]	-8	hSpCas9	positive selection	3016935
97179117	97179140	5	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	ATAGCCAGCCTTAAACATGGTGG	RIOK2	ENSG00000058729	-0.7727514786144415	[3,3]	[2,0]	-9	hSpCas9	positive selection	3084790
97173209	97173232	5	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCATGACGATTGTAATCAATTGG	RIOK2	ENSG00000058729	0.3463201053041454	[5,5]	[7,3]	6	hSpCas9	positive selection	3084791
97183125	97183148	5	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TGACTTCAGGGTCTTGACCGCGG	RIOK2	ENSG00000058729	-0.13944831954795178	[2,2]	[1,1]	-2	hSpCas9	positive selection	3084792
97177750	97177773	5	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TGAGTCTGTTGGAAACCAGATGG	RIOK2	ENSG00000058729	-0.8573924115653146	[2,2]	[1,0]	-9	hSpCas9	positive selection	3084793
97177735	97177758		+	24336571	A375	resistance to PLX after 7 days	ATTCTTTGCCAACACCCATCTGG	RIOK2	ENSG00000058729	-0.12510039609561452	[39,39]	[38,32]	-4	hSpCas9	positive selection	3141036
97177822	97177845		+	24336571	A375	resistance to PLX after 7 days	CATTTGTCAACCGATAGCCCTGG	RIOK2	ENSG00000058729	-0.531973774584731	[17,13]	[8,11]	-9	hSpCas9	positive selection	3141037
97179109	97179132		+	24336571	A375	resistance to PLX after 7 days	TATTACAGCCACCATGTTTAAGG	RIOK2	ENSG00000058729	-0.09157233264067188	[26,25]	[22,26]	-3	hSpCas9	positive selection	3141038
97179120	97179143		-	24336571	A375	resistance to PLX after 7 days	TCTATAGCCAGCCTTAAACATGG	RIOK2	ENSG00000058729	0.2458423319786054	[4,4]	[5,4]	7	hSpCas9	positive selection	3141039
97177735	97177758		+	24336571	A375	resistance to PLX after 14 days	ATTCTTTGCCAACACCCATCTGG	RIOK2	ENSG00000058729	-0.5183537642270731	[33,40]	[10,11]	-6	hSpCas9	positive selection	3198829
97177822	97177845		+	24336571	A375	resistance to PLX after 14 days	CATTTGTCAACCGATAGCCCTGG	RIOK2	ENSG00000058729	-0.9020957408505339	[19,13]	[3,3]	-9	hSpCas9	positive selection	3198830
97179109	97179132		+	24336571	A375	resistance to PLX after 14 days	TATTACAGCCACCATGTTTAAGG	RIOK2	ENSG00000058729	-0.10560319306985766	[27,18]	[9,9]	-1	hSpCas9	positive selection	3198831
97179120	97179143		-	24336571	A375	resistance to PLX after 14 days	TCTATAGCCAGCCTTAAACATGG	RIOK2	ENSG00000058729	0.050510018509783094	[3,3]	[1,1]	0	hSpCas9	positive selection	3198832
97177735	97177758		+	24336571	A375	viability after 7 days	ATTCTTTGCCAACACCCATCTGG	RIOK2	ENSG00000058729	0.36560061967097046	[31]	[39,39]	5	hSpCas9	negative selection	3256622
97177822	97177845		+	24336571	A375	viability after 7 days	CATTTGTCAACCGATAGCCCTGG	RIOK2	ENSG00000058729	-0.5956149643182096	[25]	[17,13]	-7	hSpCas9	negative selection	3256623
97179109	97179132		+	24336571	A375	viability after 7 days	TATTACAGCCACCATGTTTAAGG	RIOK2	ENSG00000058729	0.4066619878283385	[20]	[26,25]	6	hSpCas9	negative selection	3256624
97179120	97179143		-	24336571	A375	viability after 7 days	TCTATAGCCAGCCTTAAACATGG	RIOK2	ENSG00000058729	-1.466139979093351	[14]	[4,4]	-9	hSpCas9	negative selection	3256625
97177735	97177758		+	24336571	A375	viability after 14 days	ATTCTTTGCCAACACCCATCTGG	RIOK2	ENSG00000058729	0.28437735501253636	[31]	[33,40]	3	hSpCas9	negative selection	3314415
97177822	97177845		+	24336571	A375	viability after 14 days	CATTTGTCAACCGATAGCCCTGG	RIOK2	ENSG00000058729	-0.4548782403609248	[25]	[19,13]	-5	hSpCas9	negative selection	3314416
97179109	97179132		+	24336571	A375	viability after 14 days	TATTACAGCCACCATGTTTAAGG	RIOK2	ENSG00000058729	0.21702568633797314	[20]	[27,18]	3	hSpCas9	negative selection	3314417
97179120	97179143		-	24336571	A375	viability after 14 days	TCTATAGCCAGCCTTAAACATGG	RIOK2	ENSG00000058729	-1.7050331050982506	[14]	[3,3]	-9	hSpCas9	negative selection	3314418
97177735	97177758	5	+	27383988	293T	resistance to West Nile virus (flavivirus)	ATTCTTTGCCAACACCCATCTGG	RIOK2	ENSG00000058729	0.3265888738829487	[121,121]	[0,0]	1	hSpCas9	positive selection	3389909
97177179	97177202	5	-	27383988	293T	resistance to West Nile virus (flavivirus)	AACGCGATTATCATAAACATAGG	RIOK2	ENSG00000058729	3.733764255388822	[114,114]	[9,9]	9	hSpCas9	positive selection	3389910
97177133	97177156	5	-	27383988	293T	resistance to West Nile virus (flavivirus)	ATCTCGTCTCTCTGCCATGAAGG	RIOK2	ENSG00000058729	-0.6615370258287593	[241,241]	[0,0]	-4	hSpCas9	positive selection	3389911
97179117	97179140	5	-	26780180	HT29	viability (Avana library 4 designs)	ATAGCCAGCCTTAAACATGGTGG	RIOK2	ENSG00000058729	4.12531445064603	[]	[]	9	hSpCas9	negative selection	3455297
97173208	97173231	5	+	26780180	HT29	viability (Avana library 4 designs)	GCATGACGATTGTAATCAATTGG	RIOK2	ENSG00000058729	0.258548078695699	[]	[]	0	hSpCas9	negative selection	3455298
97183125	97183148	5	-	26780180	HT29	viability (Avana library 4 designs)	TGACTTCAGGGTCTTGACCGCGG	RIOK2	ENSG00000058729	6.00637747507437	[]	[]	9	hSpCas9	negative selection	3455299
97177750	97177773	5	-	26780180	HT29	viability (Avana library 4 designs)	TGAGTCTGTTGGAAACCAGATGG	RIOK2	ENSG00000058729	4.74868501477223	[]	[]	9	hSpCas9	negative selection	3455300
97183125	97183148	5	-	26780180	A375	viability (Avana lentiCRISPRv2)	TGACTTCAGGGTCTTGACCGCGG	RIOK2	ENSG00000058729	-12.5202061693047	[]	[]	-8	hSpCas9	negative selection	3553222
97179117	97179140	5	-	26780180	A375	viability (Avana lentiCRISPRv2)	ATAGCCAGCCTTAAACATGGTGG	RIOK2	ENSG00000058729	-10.6631347019148	[]	[]	-8	hSpCas9	negative selection	3553223
97177750	97177773	5	-	26780180	A375	viability (Avana lentiCRISPRv2)	TGAGTCTGTTGGAAACCAGATGG	RIOK2	ENSG00000058729	0.200054604610376	[]	[]	0	hSpCas9	negative selection	3553224
97173208	97173231	5	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCATGACGATTGTAATCAATTGG	RIOK2	ENSG00000058729	-3.91442174966391	[]	[]	-4	hSpCas9	negative selection	3553225
97179138	97179161	5	+	26780180	A375	viability (Avana lentiCRISPRv2)	ATAGAAGCAATCAAACTGCCGGG	RIOK2	ENSG00000058729	-9.41335651338166	[]	[]	-7	hSpCas9	negative selection	3553226
97183171	97183194	5	+	26780180	A375	viability (Avana lentiCRISPRv2)	GGCCACATTCACTTTCCCCATGG	RIOK2	ENSG00000058729	-17.6763828999561	[]	[]	-9	hSpCas9	negative selection	3553227
97183125	97183148	5	-	26780180	A375	viability (Avana lentiGuide)	TGACTTCAGGGTCTTGACCGCGG	RIOK2	ENSG00000058729	30.542585586234	[]	[]	9	hSpCas9	negative selection	3661881
97179117	97179140	5	-	26780180	A375	viability (Avana lentiGuide)	ATAGCCAGCCTTAAACATGGTGG	RIOK2	ENSG00000058729	31.0977211713544	[]	[]	9	hSpCas9	negative selection	3661882
97177750	97177773	5	-	26780180	A375	viability (Avana lentiGuide)	TGAGTCTGTTGGAAACCAGATGG	RIOK2	ENSG00000058729	-0.0964364046837045	[]	[]	0	hSpCas9	negative selection	3661883
97173208	97173231	5	+	26780180	A375	viability (Avana lentiGuide)	GCATGACGATTGTAATCAATTGG	RIOK2	ENSG00000058729	-2.33487339615775	[]	[]	-4	hSpCas9	negative selection	3661884
97179138	97179161	5	+	26780180	A375	viability (Avana lentiGuide)	ATAGAAGCAATCAAACTGCCGGG	RIOK2	ENSG00000058729	20.9776205156306	[]	[]	8	hSpCas9	negative selection	3661885
97183171	97183194	5	+	26780180	A375	viability (Avana lentiGuide)	GGCCACATTCACTTTCCCCATGG	RIOK2	ENSG00000058729	25.1322191023321	[]	[]	9	hSpCas9	negative selection	3661886
97183125	97183148	5	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TGACTTCAGGGTCTTGACCGCGG	RIOK2	ENSG00000058729	-1.6812976016917556	[5]	[1,0]	-9	hSpCas9	positive selection	3770488
97179117	97179140	5	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ATAGCCAGCCTTAAACATGGTGG	RIOK2	ENSG00000058729	-1.6862780644462267	[5]	[1,0]	-9	hSpCas9	positive selection	3770489
97177750	97177773	5	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TGAGTCTGTTGGAAACCAGATGG	RIOK2	ENSG00000058729	-0.4835661866787412	[4]	[3,2]	-6	hSpCas9	positive selection	3770490
97173208	97173231	5	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCATGACGATTGTAATCAATTGG	RIOK2	ENSG00000058729	-0.028724918850684122	[6]	[6,6]	0	hSpCas9	positive selection	3770491
97179138	97179161	5	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ATAGAAGCAATCAAACTGCCGGG	RIOK2	ENSG00000058729	-0.35214788546230524	[4]	[3,3]	-5	hSpCas9	positive selection	3770492
97183171	97183194	5	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGCCACATTCACTTTCCCCATGG	RIOK2	ENSG00000058729	-1.320068368040602	[5]	[2,0]	-9	hSpCas9	positive selection	3770493
97183125	97183148	5	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TGACTTCAGGGTCTTGACCGCGG	RIOK2	ENSG00000058729	-0.7299829018257391	[6]	[2,2]	-7	hSpCas9	positive selection	3879095
97179117	97179140	5	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ATAGCCAGCCTTAAACATGGTGG	RIOK2	ENSG00000058729	-2.011964617644826	[5]	[0,0]	-9	hSpCas9	positive selection	3879096
97177750	97177773	5	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TGAGTCTGTTGGAAACCAGATGG	RIOK2	ENSG00000058729	-0.17426366213539565	[5]	[2,4]	-2	hSpCas9	positive selection	3879097
97173208	97173231	5	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCATGACGATTGTAATCAATTGG	RIOK2	ENSG00000058729	0.3420573374918707	[7]	[7,7]	8	hSpCas9	positive selection	3879098
97179138	97179161	5	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ATAGAAGCAATCAAACTGCCGGG	RIOK2	ENSG00000058729	-1.4655197727089442	[4]	[0,0]	-9	hSpCas9	positive selection	3879099
97183171	97183194	5	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGCCACATTCACTTTCCCCATGG	RIOK2	ENSG00000058729	-1.8738782597236259	[5]	[0,1]	-9	hSpCas9	positive selection	3879100
97177179	97177202	5	-	26780180	A375	viability	AACGCGATTATCATAAACATAGG	RIOK2	ENSG00000058729	1.31634764551635	[]	[]	7	hSpCas9	negative selection	3989199
97163118	97163141	5	-	26780180	A375	viability	ATATATTTACCAAGCAACGTAGG	RIOK2	ENSG00000058729	1.35814555067866	[]	[]	7	hSpCas9	negative selection	3989200
97177133	97177156	5	-	26780180	A375	viability	ATCTCGTCTCTCTGCCATGAAGG	RIOK2	ENSG00000058729	1.07455064961041	[]	[]	5	hSpCas9	negative selection	3989201
97177735	97177758	5	+	26780180	A375	viability	ATTCTTTGCCAACACCCATCTGG	RIOK2	ENSG00000058729	1.43581753277146	[]	[]	8	hSpCas9	negative selection	3989202
97177822	97177845	5	+	26780180	A375	viability	CATTTGTCAACCGATAGCCCTGG	RIOK2	ENSG00000058729	2.00487520372397	[]	[]	9	hSpCas9	negative selection	3989203
97163149	97163172	5	-	26780180	A375	viability	GTCAGACGTCGATTGCAGAAAGG	RIOK2	ENSG00000058729	0.85531454753485	[]	[]	3	hSpCas9	negative selection	3989204
97177179	97177202	5	-	26780180	HT29	viability (GeCKOv2 library)	AACGCGATTATCATAAACATAGG	RIOK2	ENSG00000058729	0.758471392773211	[]	[]	3	hSpCas9	negative selection	4097165
97163118	97163141	5	-	26780180	HT29	viability (GeCKOv2 library)	ATATATTTACCAAGCAACGTAGG	RIOK2	ENSG00000058729	1.51472885750285	[]	[]	7	hSpCas9	negative selection	4097166
97177133	97177156	5	-	26780180	HT29	viability (GeCKOv2 library)	ATCTCGTCTCTCTGCCATGAAGG	RIOK2	ENSG00000058729	0.791495821010566	[]	[]	3	hSpCas9	negative selection	4097167
97177735	97177758	5	+	26780180	HT29	viability (GeCKOv2 library)	ATTCTTTGCCAACACCCATCTGG	RIOK2	ENSG00000058729	1.99704009384959	[]	[]	9	hSpCas9	negative selection	4097168
97177822	97177845	5	+	26780180	HT29	viability (GeCKOv2 library)	CATTTGTCAACCGATAGCCCTGG	RIOK2	ENSG00000058729	2.674293766321	[]	[]	9	hSpCas9	negative selection	4097169
97163149	97163172	5	-	26780180	HT29	viability (GeCKOv2 library)	GTCAGACGTCGATTGCAGAAAGG	RIOK2	ENSG00000058729	1.2301748478987	[]	[]	6	hSpCas9	negative selection	4097170
97177735	97177758	5	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	ATTCTTTGCCAACACCCATCTGG	RIOK2	ENSG00000058729	0.08554522181825691	[5]	[3,3]	2	hSpCas9	positive selection	4166532
97177822	97177845	5	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CATTTGTCAACCGATAGCCCTGG	RIOK2	ENSG00000058729	-0.24682421038018654	[4]	[2,1]	-5	hSpCas9	positive selection	4166533
97179109	97179132	5	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TATTACAGCCACCATGTTTAAGG	RIOK2	ENSG00000058729	0.0353910088605115	[4]	[3,3]	0	hSpCas9	positive selection	4166534
97179120	97179143	5	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TCTATAGCCAGCCTTAAACATGG	RIOK2	ENSG00000058729	-0.7161534656143174	[2]	[0,0]	-9	hSpCas9	positive selection	4166535
97177735	97177758	5	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	ATTCTTTGCCAACACCCATCTGG	RIOK2	ENSG00000058729	0.9611807630082407	[4]	[3,1,5,4]	6	hSpCas9	positive selection	4230554
97177822	97177845	5	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CATTTGTCAACCGATAGCCCTGG	RIOK2	ENSG00000058729	0.7137870622675103	[4]	[1,0,0,4]	4	hSpCas9	positive selection	4230555
97179109	97179132	5	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TATTACAGCCACCATGTTTAAGG	RIOK2	ENSG00000058729	0.6476505129267238	[3]	[0,0,2,3]	4	hSpCas9	positive selection	4230556
97179120	97179143	5	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TCTATAGCCAGCCTTAAACATGG	RIOK2	ENSG00000058729	-0.6961589672094157	[2]	[0,0,0,0]	-8	hSpCas9	positive selection	4230557
97177822	97177845	5	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CATTTGTCAACCGATAGCCCTGG	RIOK2	ENSG00000058729	-0.7676260606408349	[2]	[0,0]	-9	hSpCas9	positive selection	4294941
97163149	97163172	5	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GTCAGACGTCGATTGCAGAAAGG	RIOK2	ENSG00000058729	-0.36666164471062107	[2]	[2,0]	-7	hSpCas9	positive selection	4294942
97163118	97163141	5	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ATATATTTACCAAGCAACGTAGG	RIOK2	ENSG00000058729	0.04268006755275028	[4]	[3,2]	0	hSpCas9	positive selection	4294943
97177735	97177758	5	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ATTCTTTGCCAACACCCATCTGG	RIOK2	ENSG00000058729	0.3260264882673447	[2]	[1,2]	6	hSpCas9	positive selection	4359195
97177179	97177202	5	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AACGCGATTATCATAAACATAGG	RIOK2	ENSG00000058729	-0.09643043973080388	[2]	[1,1]	-2	hSpCas9	positive selection	4359196
97177133	97177156	5	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ATCTCGTCTCTCTGCCATGAAGG	RIOK2	ENSG00000058729	0.13755897746438717	[3]	[3,2]	2	hSpCas9	positive selection	4359197
97173203	97173225	5	-	27760321	OCIAML3	viability	GATTACAATCGTCATGCAGTGG	RIOK2	ENSG00000058729	-2.0583682119106523	[510,446]	[64,121]	-9	hSpCas9	negative selection	4434760
97177179	97177201	5	-	27760321	OCIAML3	viability	ACGCGATTATCATAAACATAGG	RIOK2	ENSG00000058729	0.534593302603263	[81,39]	[59,76]	6	hSpCas9	negative selection	4434761
97177736	97177758	5	+	27760321	OCIAML3	viability	TTCTTTGCCAACACCCATCTGG	RIOK2	ENSG00000058729	-0.1677155917972194	[578,507]	[361,397]	-2	hSpCas9	negative selection	4434762
97177823	97177845	5	+	27760321	OCIAML3	viability	ATTTGTCAACCGATAGCCCTGG	RIOK2	ENSG00000058729	-1.1050380167448934	[822,675]	[209,350]	-7	hSpCas9	negative selection	4434763
97179120	97179142	5	-	27760321	OCIAML3	viability	CTATAGCCAGCCTTAAACATGG	RIOK2	ENSG00000058729	-0.7334910682162921	[203,165]	[63,115]	-6	hSpCas9	negative selection	4434764
97173203	97173225	5	-	27760321	OCIAML2	viability	GATTACAATCGTCATGCAGTGG	RIOK2	ENSG00000058729	-1.4835952329469173	[510,446]	[120,160]	-8	hSpCas9	negative selection	4518223
97177179	97177201	5	-	27760321	OCIAML2	viability	ACGCGATTATCATAAACATAGG	RIOK2	ENSG00000058729	-0.5837240016496459	[81,39]	[16,51]	-6	hSpCas9	negative selection	4518224
97177736	97177758	5	+	27760321	OCIAML2	viability	TTCTTTGCCAACACCCATCTGG	RIOK2	ENSG00000058729	-1.0687766260749538	[578,507]	[184,240]	-7	hSpCas9	negative selection	4518225
97177823	97177845	5	+	27760321	OCIAML2	viability	ATTTGTCAACCGATAGCCCTGG	RIOK2	ENSG00000058729	-1.0005968931869682	[822,675]	[298,304]	-7	hSpCas9	negative selection	4518226
97179120	97179142	5	-	27760321	OCIAML2	viability	CTATAGCCAGCCTTAAACATGG	RIOK2	ENSG00000058729	-1.713119601769385	[203,165]	[47,41]	-9	hSpCas9	negative selection	4518227
97173203	97173225	5	-	27760321	MV411	viability	GATTACAATCGTCATGCAGTGG	RIOK2	ENSG00000058729	-3.444200521822475	[510,446]	[0,70]	-9	hSpCas9	negative selection	4601686
97177179	97177201	5	-	27760321	MV411	viability	ACGCGATTATCATAAACATAGG	RIOK2	ENSG00000058729	-5.294569289750324	[81,39]	[0,0]	-9	hSpCas9	negative selection	4601687
97177736	97177758	5	+	27760321	MV411	viability	TTCTTTGCCAACACCCATCTGG	RIOK2	ENSG00000058729	-0.2624912584514589	[578,507]	[263,349]	-2	hSpCas9	negative selection	4601688
97177823	97177845	5	+	27760321	MV411	viability	ATTTGTCAACCGATAGCCCTGG	RIOK2	ENSG00000058729	-1.1734610874974418	[822,675]	[21,512]	-6	hSpCas9	negative selection	4601689
97179120	97179142	5	-	27760321	MV411	viability	CTATAGCCAGCCTTAAACATGG	RIOK2	ENSG00000058729	-0.11551607060399993	[203,165]	[0,278]	-1	hSpCas9	negative selection	4601690
97173203	97173225	5	-	27760321	HL60	viability	GATTACAATCGTCATGCAGTGG	RIOK2	ENSG00000058729	-1.2721422325830296	[510,446]	[232,85]	-8	hSpCas9	negative selection	4685149
97177179	97177201	5	-	27760321	HL60	viability	ACGCGATTATCATAAACATAGG	RIOK2	ENSG00000058729	-4.2553787460816235	[81,39]	[3,0]	-9	hSpCas9	negative selection	4685150
97177736	97177758	5	+	27760321	HL60	viability	TTCTTTGCCAACACCCATCTGG	RIOK2	ENSG00000058729	-1.1238222278251695	[578,507]	[229,174]	-8	hSpCas9	negative selection	4685151
97177823	97177845	5	+	27760321	HL60	viability	ATTTGTCAACCGATAGCCCTGG	RIOK2	ENSG00000058729	-0.8297939202940706	[822,675]	[402,278]	-7	hSpCas9	negative selection	4685152
97179120	97179142	5	-	27760321	HL60	viability	CTATAGCCAGCCTTAAACATGG	RIOK2	ENSG00000058729	-1.5069446017862143	[203,165]	[32,73]	-8	hSpCas9	negative selection	4685153
97173203	97173225	5	-	27760321	HT1080	viability	GATTACAATCGTCATGCAGTGG	RIOK2	ENSG00000058729	-7.308841551287687	[446,348]	[0,0]	-9	hSpCas9	negative selection	4768612
97177179	97177201	5	-	27760321	HT1080	viability	ACGCGATTATCATAAACATAGG	RIOK2	ENSG00000058729	-3.8213028996417866	[39,30]	[0,0]	-8	hSpCas9	negative selection	4768613
97177736	97177758	5	+	27760321	HT1080	viability	TTCTTTGCCAACACCCATCTGG	RIOK2	ENSG00000058729	-7.494074989723459	[507,396]	[0,0]	-9	hSpCas9	negative selection	4768614
97177823	97177845	5	+	27760321	HT1080	viability	ATTTGTCAACCGATAGCCCTGG	RIOK2	ENSG00000058729	-4.877252989617453	[675,527]	[0,15]	-8	hSpCas9	negative selection	4768615
97179120	97179142	5	-	27760321	HT1080	viability	CTATAGCCAGCCTTAAACATGG	RIOK2	ENSG00000058729	-5.881941192126951	[165,129]	[0,0]	-8	hSpCas9	negative selection	4768616
97173203	97173225	5	-	27760321	HT29	viability after 7 days	GATTACAATCGTCATGCAGTGG	RIOK2	ENSG00000058729	-1.2977877890128757	[446,348]	[149,230,233]	-9	hSpCas9	negative selection	4852075
97177179	97177201	5	-	27760321	HT29	viability after 7 days	ACGCGATTATCATAAACATAGG	RIOK2	ENSG00000058729	-0.7774242764985275	[39,30]	[37,2,39]	-8	hSpCas9	negative selection	4852076
97177736	97177758	5	+	27760321	HT29	viability after 7 days	TTCTTTGCCAACACCCATCTGG	RIOK2	ENSG00000058729	-0.5132731043880603	[507,396]	[321,602,288]	-6	hSpCas9	negative selection	4852077
97177823	97177845	5	+	27760321	HT29	viability after 7 days	ATTTGTCAACCGATAGCCCTGG	RIOK2	ENSG00000058729	0.032905555005706244	[675,527]	[845,672,860]	0	hSpCas9	negative selection	4852078
97179120	97179142	5	-	27760321	HT29	viability after 7 days	CTATAGCCAGCCTTAAACATGG	RIOK2	ENSG00000058729	-0.8940761544204041	[165,129]	[46,111,138]	-8	hSpCas9	negative selection	4852079
97173203	97173225	5	-	27760321	HT29	viability after 25 days	GATTACAATCGTCATGCAGTGG	RIOK2	ENSG00000058729	-6.236521846234935	[446,348]	[14,0,0]	-9	hSpCas9	negative selection	4935538
97177179	97177201	5	-	27760321	HT29	viability after 25 days	ACGCGATTATCATAAACATAGG	RIOK2	ENSG00000058729	-0.27398796390458724	[39,30]	[34,35,28]	-3	hSpCas9	negative selection	4935539
97177736	97177758	5	+	27760321	HT29	viability after 25 days	TTCTTTGCCAACACCCATCTGG	RIOK2	ENSG00000058729	-4.125659762621618	[507,396]	[3,8,82]	-9	hSpCas9	negative selection	4935540
97177823	97177845	5	+	27760321	HT29	viability after 25 days	ATTTGTCAACCGATAGCCCTGG	RIOK2	ENSG00000058729	-3.3436022672202803	[675,527]	[59,38,108]	-8	hSpCas9	negative selection	4935541
97179120	97179142	5	-	27760321	HT29	viability after 25 days	CTATAGCCAGCCTTAAACATGG	RIOK2	ENSG00000058729	-0.9221387822620253	[165,129]	[200,44,5]	-6	hSpCas9	negative selection	4935542
97173203	97173225	5	-	27760321	HT29	viability after 22 days	GATTACAATCGTCATGCAGTGG	RIOK2	ENSG00000058729	-8.84584244799347	[446,348]	[0,0,0]	-9	hSpCas9	negative selection	5019001
97177179	97177201	5	-	27760321	HT29	viability after 22 days	ACGCGATTATCATAAACATAGG	RIOK2	ENSG00000058729	-0.568502103654819	[39,30]	[29,16,35]	-5	hSpCas9	negative selection	5019002
97177736	97177758	5	+	27760321	HT29	viability after 22 days	TTCTTTGCCAACACCCATCTGG	RIOK2	ENSG00000058729	-4.794213925246605	[507,396]	[6,18,30]	-9	hSpCas9	negative selection	5019003
97177823	97177845	5	+	27760321	HT29	viability after 22 days	ATTTGTCAACCGATAGCCCTGG	RIOK2	ENSG00000058729	-3.174528575747476	[675,527]	[19,113,98]	-8	hSpCas9	negative selection	5019004
97179120	97179142	5	-	27760321	HT29	viability after 22 days	CTATAGCCAGCCTTAAACATGG	RIOK2	ENSG00000058729	-0.6709435117199702	[165,129]	[156,68,94]	-5	hSpCas9	negative selection	5019005
97173203	97173225	5	-	27760321	HT29	viability after 19 days	GATTACAATCGTCATGCAGTGG	RIOK2	ENSG00000058729	-4.677574109530649	[446,348]	[55,0,0]	-9	hSpCas9	negative selection	5102464
97177179	97177201	5	-	27760321	HT29	viability after 19 days	ACGCGATTATCATAAACATAGG	RIOK2	ENSG00000058729	0.5844913690328437	[39,30]	[45,74,59]	6	hSpCas9	negative selection	5102465
97177736	97177758	5	+	27760321	HT29	viability after 19 days	TTCTTTGCCAACACCCATCTGG	RIOK2	ENSG00000058729	-2.8351503553041226	[507,396]	[40,174,0]	-8	hSpCas9	negative selection	5102466
97177823	97177845	5	+	27760321	HT29	viability after 19 days	ATTTGTCAACCGATAGCCCTGG	RIOK2	ENSG00000058729	-3.4222069475225947	[675,527]	[166,14,22]	-9	hSpCas9	negative selection	5102467
97179120	97179142	5	-	27760321	HT29	viability after 19 days	CTATAGCCAGCCTTAAACATGG	RIOK2	ENSG00000058729	-0.7561088543550847	[165,129]	[132,148,24]	-5	hSpCas9	negative selection	5102468
97173203	97173225	5	-	27760321	HT29	viability after 16 days	GATTACAATCGTCATGCAGTGG	RIOK2	ENSG00000058729	-6.524879392828229	[446,348]	[8,0,4]	-9	hSpCas9	negative selection	5185927
97177179	97177201	5	-	27760321	HT29	viability after 16 days	ACGCGATTATCATAAACATAGG	RIOK2	ENSG00000058729	0.8152153435136182	[39,30]	[3,5,194]	8	hSpCas9	negative selection	5185928
97177736	97177758	5	+	27760321	HT29	viability after 16 days	TTCTTTGCCAACACCCATCTGG	RIOK2	ENSG00000058729	-2.116329553437773	[507,396]	[0,91,246]	-8	hSpCas9	negative selection	5185929
97177823	97177845	5	+	27760321	HT29	viability after 16 days	ATTTGTCAACCGATAGCCCTGG	RIOK2	ENSG00000058729	-3.053229425150639	[675,527]	[58,131,48]	-9	hSpCas9	negative selection	5185930
97179120	97179142	5	-	27760321	HT29	viability after 16 days	CTATAGCCAGCCTTAAACATGG	RIOK2	ENSG00000058729	-2.389513520604587	[165,129]	[17,51,22]	-8	hSpCas9	negative selection	5185931
97173203	97173225	5	-	27760321	HT29	viability after 13 days	GATTACAATCGTCATGCAGTGG	RIOK2	ENSG00000058729	-2.768935205965147	[446,348]	[17,128,56]	-9	hSpCas9	negative selection	5269390
97177179	97177201	5	-	27760321	HT29	viability after 13 days	ACGCGATTATCATAAACATAGG	RIOK2	ENSG00000058729	0.23812751748150118	[39,30]	[73,29,41]	3	hSpCas9	negative selection	5269391
97177736	97177758	5	+	27760321	HT29	viability after 13 days	TTCTTTGCCAACACCCATCTGG	RIOK2	ENSG00000058729	-2.7372976491006815	[507,396]	[64,122,49]	-9	hSpCas9	negative selection	5269392
97177823	97177845	5	+	27760321	HT29	viability after 13 days	ATTTGTCAACCGATAGCCCTGG	RIOK2	ENSG00000058729	-2.2680870223965623	[675,527]	[98,206,129]	-9	hSpCas9	negative selection	5269393
97179120	97179142	5	-	27760321	HT29	viability after 13 days	CTATAGCCAGCCTTAAACATGG	RIOK2	ENSG00000058729	-2.390158224976864	[165,129]	[8,67,21]	-9	hSpCas9	negative selection	5269394
97173203	97173225	5	-	27760321	HT29	viability after 10 days	GATTACAATCGTCATGCAGTGG	RIOK2	ENSG00000058729	-2.570459260214671	[446,348]	[48,159,44]	-9	hSpCas9	negative selection	5352853
97177179	97177201	5	-	27760321	HT29	viability after 10 days	ACGCGATTATCATAAACATAGG	RIOK2	ENSG00000058729	-0.061892559771251854	[39,30]	[17,106,4]	-1	hSpCas9	negative selection	5352854
97177736	97177758	5	+	27760321	HT29	viability after 10 days	TTCTTTGCCAACACCCATCTGG	RIOK2	ENSG00000058729	-1.2394652006045217	[507,396]	[397,170,148]	-8	hSpCas9	negative selection	5352855
97177823	97177845	5	+	27760321	HT29	viability after 10 days	ATTTGTCAACCGATAGCCCTGG	RIOK2	ENSG00000058729	-1.5388518296449547	[675,527]	[204,281,288]	-8	hSpCas9	negative selection	5352856
97179120	97179142	5	-	27760321	HT29	viability after 10 days	CTATAGCCAGCCTTAAACATGG	RIOK2	ENSG00000058729	-1.6724171685750115	[165,129]	[102,58,12]	-8	hSpCas9	negative selection	5352857
97173203	97173225	5	-	27760321	MOLM13	viability	GATTACAATCGTCATGCAGTGG	RIOK2	ENSG00000058729	-3.01694489370817	[510,446]	[55,13]	-9	hSpCas9	negative selection	5436316
97177179	97177201	5	-	27760321	MOLM13	viability	ACGCGATTATCATAAACATAGG	RIOK2	ENSG00000058729	1.9088824014414245	[81,39]	[24,211]	9	hSpCas9	negative selection	5436317
97177736	97177758	5	+	27760321	MOLM13	viability	TTCTTTGCCAACACCCATCTGG	RIOK2	ENSG00000058729	-0.369415066675559	[578,507]	[251,223]	-2	hSpCas9	negative selection	5436318
97177823	97177845	5	+	27760321	MOLM13	viability	ATTTGTCAACCGATAGCCCTGG	RIOK2	ENSG00000058729	-1.48224837251275	[822,675]	[168,134]	-7	hSpCas9	negative selection	5436319
97179120	97179142	5	-	27760321	MOLM13	viability	CTATAGCCAGCCTTAAACATGG	RIOK2	ENSG00000058729	-0.6459722758244786	[203,165]	[0,121]	-4	hSpCas9	negative selection	5436320
97183224	97183247	5	+	27661255	K562	viability	GACGACAGCCGCAAAGCGTAAGG	RIOK2	ENSG00000058729	-4.135621676772182	[736,635]	[40,22]	-9	dCas9-KRAB	negative selection	5507573
97183028	97183051	5	-	27661255	K562	viability	GGATCTGAGCAGGCACACTCTGG	RIOK2	ENSG00000058729	-1.0623612090857923	[487,419]	[212,140]	-8	dCas9-KRAB	negative selection	5507574
97183204	97183227	5	-	27661255	K562	viability	GTCGGAGAGGCATCTGGGTTCGG	RIOK2	ENSG00000058729	-3.3711538707333015	[364,306]	[18,31]	-9	dCas9-KRAB	negative selection	5507575
97177822	97177845	5	+	27260156	BXPC3	viability	CATTTGTCAACCGATAGCCCTGG	RIOK2	ENSG00000058729	-0.07559660968884019	[336]	[300,255,417,374]	-2	hSpCas9	negative selection	5567401
97163149	97163172	5	-	27260156	BXPC3	viability	GTCAGACGTCGATTGCAGAAAGG	RIOK2	ENSG00000058729	-0.055706882306160055	[338]	[333,289,331,418]	-1	hSpCas9	negative selection	5567402
97163118	97163141	5	-	27260156	BXPC3	viability	ATATATTTACCAAGCAACGTAGG	RIOK2	ENSG00000058729	-0.4341482020722599	[1008]	[772,699,689,983]	-7	hSpCas9	negative selection	5567403
97177735	97177758	5	+	27260156	BXPC3	viability	ATTCTTTGCCAACACCCATCTGG	RIOK2	ENSG00000058729	0.277465387834506	[296]	[429,331,305,437]	6	hSpCas9	negative selection	5631655
97177179	97177202	5	-	27260156	BXPC3	viability	AACGCGATTATCATAAACATAGG	RIOK2	ENSG00000058729	-0.25232649501551496	[359]	[415,242,266,329]	-5	hSpCas9	negative selection	5631656
97177133	97177156	5	-	27260156	BXPC3	viability	ATCTCGTCTCTCTGCCATGAAGG	RIOK2	ENSG00000058729	-0.3485710508372122	[849]	[624,727,692,753]	-7	hSpCas9	negative selection	5631657
97177822	97177845	5	+	27260156	A673	viability	CATTTGTCAACCGATAGCCCTGG	RIOK2	ENSG00000058729	-0.09441895158865188	[336]	[421,376,380,337]	-2	hSpCas9	negative selection	5688652
97163149	97163172	5	-	27260156	A673	viability	GTCAGACGTCGATTGCAGAAAGG	RIOK2	ENSG00000058729	-0.3370263120895223	[338]	[314,246,312,419]	-7	hSpCas9	negative selection	5688653
97163118	97163141	5	-	27260156	A673	viability	ATATATTTACCAAGCAACGTAGG	RIOK2	ENSG00000058729	-0.5311732302074812	[1008]	[838,769,891,852]	-8	hSpCas9	negative selection	5688654
97177735	97177758	5	+	27260156	A673	viability	ATTCTTTGCCAACACCCATCTGG	RIOK2	ENSG00000058729	0.08229219603971194	[296]	[416,294,421,381]	2	hSpCas9	negative selection	5752906
97177179	97177202	5	-	27260156	A673	viability	AACGCGATTATCATAAACATAGG	RIOK2	ENSG00000058729	-0.22967020613469802	[359]	[400,372,287,418]	-5	hSpCas9	negative selection	5752907
97177133	97177156	5	-	27260156	A673	viability	ATCTCGTCTCTCTGCCATGAAGG	RIOK2	ENSG00000058729	-0.2825378310633042	[849]	[955,750,789,875]	-6	hSpCas9	negative selection	5752908
97177822	97177845	5	+	27260156	A375	viability	CATTTGTCAACCGATAGCCCTGG	RIOK2	ENSG00000058729	0.16043470620972766	[336]	[356,435,488,470]	2	hSpCas9	negative selection	5809903
97163149	97163172	5	-	27260156	A375	viability	GTCAGACGTCGATTGCAGAAAGG	RIOK2	ENSG00000058729	-0.539412747536655	[338]	[259,169,414,233]	-6	hSpCas9	negative selection	5809904
97163118	97163141	5	-	27260156	A375	viability	ATATATTTACCAAGCAACGTAGG	RIOK2	ENSG00000058729	-0.870688114672906	[1008]	[745,827,597,452]	-8	hSpCas9	negative selection	5809905
97177735	97177758	5	+	27260156	A375	viability	ATTCTTTGCCAACACCCATCTGG	RIOK2	ENSG00000058729	-0.22178889638645227	[296]	[314,379,352,167]	-3	hSpCas9	negative selection	5874157
97177179	97177202	5	-	27260156	A375	viability	AACGCGATTATCATAAACATAGG	RIOK2	ENSG00000058729	-0.9805395665735042	[359]	[237,204,188,217]	-8	hSpCas9	negative selection	5874158
97177133	97177156	5	-	27260156	A375	viability	ATCTCGTCTCTCTGCCATGAAGG	RIOK2	ENSG00000058729	-0.6130888257013177	[849]	[735,600,834,440]	-7	hSpCas9	negative selection	5874159
97177822	97177845	5	+	27260156	COLO741	viability	CATTTGTCAACCGATAGCCCTGG	RIOK2	ENSG00000058729	0.2288409694035607	[336]	[602,387,527]	5	hSpCas9	negative selection	5931154
97163149	97163172	5	-	27260156	COLO741	viability	GTCAGACGTCGATTGCAGAAAGG	RIOK2	ENSG00000058729	0.013744461832355837	[338]	[462,328,514]	0	hSpCas9	negative selection	5931155
97163118	97163141	5	-	27260156	COLO741	viability	ATATATTTACCAAGCAACGTAGG	RIOK2	ENSG00000058729	-0.21987762798511112	[1008]	[1348,1015,982]	-5	hSpCas9	negative selection	5931156
97177735	97177758	5	+	27260156	COLO741	viability	ATTCTTTGCCAACACCCATCTGG	RIOK2	ENSG00000058729	0.21905763952252605	[296]	[580,317,436]	4	hSpCas9	negative selection	5995408
97177179	97177202	5	-	27260156	COLO741	viability	AACGCGATTATCATAAACATAGG	RIOK2	ENSG00000058729	-0.535898352442575	[359]	[304,354,291]	-8	hSpCas9	negative selection	5995409
97177133	97177156	5	-	27260156	COLO741	viability	ATCTCGTCTCTCTGCCATGAAGG	RIOK2	ENSG00000058729	-0.22732821078023813	[849]	[1150,963,701]	-5	hSpCas9	negative selection	5995410
97177822	97177845	5	+	27260156	CAL120	viability	CATTTGTCAACCGATAGCCCTGG	RIOK2	ENSG00000058729	0.3543169058110913	[336]	[686,419,523]	5	hSpCas9	negative selection	6052405
97163149	97163172	5	-	27260156	CAL120	viability	GTCAGACGTCGATTGCAGAAAGG	RIOK2	ENSG00000058729	0.27985113476009366	[338]	[249,633,610]	4	hSpCas9	negative selection	6052406
97163118	97163141	5	-	27260156	CAL120	viability	ATATATTTACCAAGCAACGTAGG	RIOK2	ENSG00000058729	-0.21761058953364443	[1008]	[1132,1149,965]	-3	hSpCas9	negative selection	6052407
97177735	97177758	5	+	27260156	CAL120	viability	ATTCTTTGCCAACACCCATCTGG	RIOK2	ENSG00000058729	0.193750413309421	[296]	[587,236,466]	3	hSpCas9	negative selection	6116659
97177179	97177202	5	-	27260156	CAL120	viability	AACGCGATTATCATAAACATAGG	RIOK2	ENSG00000058729	-0.6617658767283507	[359]	[288,318,242]	-7	hSpCas9	negative selection	6116660
97177133	97177156	5	-	27260156	CAL120	viability	ATCTCGTCTCTCTGCCATGAAGG	RIOK2	ENSG00000058729	0.08576155190471946	[849]	[1441,730,1239]	1	hSpCas9	negative selection	6116661
97177822	97177845	5	+	27260156	CADOES1	viability	CATTTGTCAACCGATAGCCCTGG	RIOK2	ENSG00000058729	0.29037660629147966	[336]	[306,360,516,346]	5	hSpCas9	negative selection	6173656
97163149	97163172	5	-	27260156	CADOES1	viability	GTCAGACGTCGATTGCAGAAAGG	RIOK2	ENSG00000058729	-0.2637837151112956	[338]	[259,160,345,283]	-4	hSpCas9	negative selection	6173657
97163118	97163141	5	-	27260156	CADOES1	viability	ATATATTTACCAAGCAACGTAGG	RIOK2	ENSG00000058729	-0.38725071793053933	[1008]	[629,893,670,673]	-6	hSpCas9	negative selection	6173658
97177735	97177758	5	+	27260156	CADOES1	viability	ATTCTTTGCCAACACCCATCTGG	RIOK2	ENSG00000058729	-0.24076044388001605	[296]	[281,167,220,264]	-4	hSpCas9	negative selection	6237910
97177179	97177202	5	-	27260156	CADOES1	viability	AACGCGATTATCATAAACATAGG	RIOK2	ENSG00000058729	-1.0679407096532005	[359]	[192,94,180,169]	-9	hSpCas9	negative selection	6237911
97177133	97177156	5	-	27260156	CADOES1	viability	ATCTCGTCTCTCTGCCATGAAGG	RIOK2	ENSG00000058729	-0.34927315820128446	[849]	[626,536,545,777]	-6	hSpCas9	negative selection	6237912
97177822	97177845	5	+	27260156	EWS502	viability	CATTTGTCAACCGATAGCCCTGG	RIOK2	ENSG00000058729	-0.42041926761409887	[336]	[310,233,177,342]	-6	hSpCas9	negative selection	6294907
97163149	97163172	5	-	27260156	EWS502	viability	GTCAGACGTCGATTGCAGAAAGG	RIOK2	ENSG00000058729	-0.2190466512641932	[338]	[269,339,417,201]	-4	hSpCas9	negative selection	6294908
97163118	97163141	5	-	27260156	EWS502	viability	ATATATTTACCAAGCAACGTAGG	RIOK2	ENSG00000058729	-0.7416042659318067	[1008]	[568,586,717,695]	-8	hSpCas9	negative selection	6294909
97177735	97177758	5	+	27260156	EWS502	viability	ATTCTTTGCCAACACCCATCTGG	RIOK2	ENSG00000058729	-0.1511677376616074	[296]	[201,259,293,394]	-3	hSpCas9	negative selection	6359161
97177179	97177202	5	-	27260156	EWS502	viability	AACGCGATTATCATAAACATAGG	RIOK2	ENSG00000058729	-0.510111738838126	[359]	[243,375,197,247]	-7	hSpCas9	negative selection	6359162
97177133	97177156	5	-	27260156	EWS502	viability	ATCTCGTCTCTCTGCCATGAAGG	RIOK2	ENSG00000058729	-0.13224560516803419	[849]	[647,764,985,915]	-2	hSpCas9	negative selection	6359163
97177822	97177845	5	+	27260156	EW8	viability	CATTTGTCAACCGATAGCCCTGG	RIOK2	ENSG00000058729	-0.2970112453099091	[336]	[216,181,237,247]	-5	hSpCas9	negative selection	6416158
97163149	97163172	5	-	27260156	EW8	viability	GTCAGACGTCGATTGCAGAAAGG	RIOK2	ENSG00000058729	-0.3800682466578609	[338]	[349,146,144,227]	-6	hSpCas9	negative selection	6416159
97163118	97163141	5	-	27260156	EW8	viability	ATATATTTACCAAGCAACGTAGG	RIOK2	ENSG00000058729	-0.6974568128755223	[1008]	[708,481,446,409]	-8	hSpCas9	negative selection	6416160
97177735	97177758	5	+	27260156	EW8	viability	ATTCTTTGCCAACACCCATCTGG	RIOK2	ENSG00000058729	-0.2246246946954481	[296]	[234,296,123,184]	-4	hSpCas9	negative selection	6480412
97177179	97177202	5	-	27260156	EW8	viability	AACGCGATTATCATAAACATAGG	RIOK2	ENSG00000058729	-0.0684912335569921	[359]	[397,238,165,340]	-1	hSpCas9	negative selection	6480413
97177133	97177156	5	-	27260156	EW8	viability	ATCTCGTCTCTCTGCCATGAAGG	RIOK2	ENSG00000058729	-0.4983064257635904	[849]	[513,575,480,382]	-7	hSpCas9	negative selection	6480414
97177822	97177845	5	+	27260156	CORL105	viability	CATTTGTCAACCGATAGCCCTGG	RIOK2	ENSG00000058729	-0.1076383135307476	[336]	[403,293,471,313]	-2	hSpCas9	negative selection	6537409
97163149	97163172	5	-	27260156	CORL105	viability	GTCAGACGTCGATTGCAGAAAGG	RIOK2	ENSG00000058729	-0.29405229602164207	[338]	[239,287,473,313]	-5	hSpCas9	negative selection	6537410
97163118	97163141	5	-	27260156	CORL105	viability	ATATATTTACCAAGCAACGTAGG	RIOK2	ENSG00000058729	-0.6667947567017998	[1008]	[698,816,730,723]	-8	hSpCas9	negative selection	6537411
97177735	97177758	5	+	27260156	CORL105	viability	ATTCTTTGCCAACACCCATCTGG	RIOK2	ENSG00000058729	-0.01212468297244862	[296]	[463,224,416,290]	0	hSpCas9	negative selection	6601663
97177179	97177202	5	-	27260156	CORL105	viability	AACGCGATTATCATAAACATAGG	RIOK2	ENSG00000058729	-0.852893010809384	[359]	[268,243,223,195]	-9	hSpCas9	negative selection	6601664
97177133	97177156	5	-	27260156	CORL105	viability	ATCTCGTCTCTCTGCCATGAAGG	RIOK2	ENSG00000058729	-0.8532008348073808	[849]	[491,548,638,534]	-9	hSpCas9	negative selection	6601665
97177822	97177845	5	+	27260156	HS294T	viability	CATTTGTCAACCGATAGCCCTGG	RIOK2	ENSG00000058729	0.6699089618156967	[336]	[181,195,232,222]	8	hSpCas9	negative selection	6658660
97163149	97163172	5	-	27260156	HS294T	viability	GTCAGACGTCGATTGCAGAAAGG	RIOK2	ENSG00000058729	-0.12744064017324197	[338]	[47,112,74,276]	-2	hSpCas9	negative selection	6658661
97163118	97163141	5	-	27260156	HS294T	viability	ATATATTTACCAAGCAACGTAGG	RIOK2	ENSG00000058729	-0.33404588200905727	[1008]	[324,299,264,352]	-5	hSpCas9	negative selection	6658662
97177735	97177758	5	+	27260156	HS294T	viability	ATTCTTTGCCAACACCCATCTGG	RIOK2	ENSG00000058729	-0.11688918356821876	[296]	[118,109,75,118]	-2	hSpCas9	negative selection	6722914
97177179	97177202	5	-	27260156	HS294T	viability	AACGCGATTATCATAAACATAGG	RIOK2	ENSG00000058729	0.13838977955455695	[359]	[207,73,87,256]	2	hSpCas9	negative selection	6722915
97177133	97177156	5	-	27260156	HS294T	viability	ATCTCGTCTCTCTGCCATGAAGG	RIOK2	ENSG00000058729	-0.423703667799853	[849]	[164,216,290,328]	-6	hSpCas9	negative selection	6722916
97177822	97177845	5	+	27260156	HCC44	viability	CATTTGTCAACCGATAGCCCTGG	RIOK2	ENSG00000058729	-0.1326757442827371	[336]	[420,390,331,244]	-2	hSpCas9	negative selection	6779911
97163149	97163172	5	-	27260156	HCC44	viability	GTCAGACGTCGATTGCAGAAAGG	RIOK2	ENSG00000058729	0.006346078498806529	[338]	[524,215,489,361]	0	hSpCas9	negative selection	6779912
97163118	97163141	5	-	27260156	HCC44	viability	ATATATTTACCAAGCAACGTAGG	RIOK2	ENSG00000058729	-0.6689731371510872	[1008]	[489,783,959,644]	-7	hSpCas9	negative selection	6779913
97177735	97177758	5	+	27260156	HCC44	viability	ATTCTTTGCCAACACCCATCTGG	RIOK2	ENSG00000058729	0.3216459356793352	[296]	[267,356,684,406]	5	hSpCas9	negative selection	6844165
97177179	97177202	5	-	27260156	HCC44	viability	AACGCGATTATCATAAACATAGG	RIOK2	ENSG00000058729	0.006740738251907852	[359]	[419,457,588,197]	0	hSpCas9	negative selection	6844166
97177133	97177156	5	-	27260156	HCC44	viability	ATCTCGTCTCTCTGCCATGAAGG	RIOK2	ENSG00000058729	-0.009331995038464602	[849]	[1088,678,1068,1043]	0	hSpCas9	negative selection	6844167
97177822	97177845	5	+	27260156	G402	viability	CATTTGTCAACCGATAGCCCTGG	RIOK2	ENSG00000058729	-0.10736124149444304	[336]	[508,365,373,297]	-1	hSpCas9	negative selection	6901162
97163149	97163172	5	-	27260156	G402	viability	GTCAGACGTCGATTGCAGAAAGG	RIOK2	ENSG00000058729	-0.4318290128866067	[338]	[240,371,284,320]	-5	hSpCas9	negative selection	6901163
97163118	97163141	5	-	27260156	G402	viability	ATATATTTACCAAGCAACGTAGG	RIOK2	ENSG00000058729	-0.5694733376199228	[1008]	[1192,880,809,502]	-6	hSpCas9	negative selection	6901164
97177735	97177758	5	+	27260156	G402	viability	ATTCTTTGCCAACACCCATCTGG	RIOK2	ENSG00000058729	0.38106735021574356	[296]	[343,611,433,484]	5	hSpCas9	negative selection	6965416
97177179	97177202	5	-	27260156	G402	viability	AACGCGATTATCATAAACATAGG	RIOK2	ENSG00000058729	-1.3797194247029096	[359]	[102,254,204,109]	-9	hSpCas9	negative selection	6965417
97177133	97177156	5	-	27260156	G402	viability	ATCTCGTCTCTCTGCCATGAAGG	RIOK2	ENSG00000058729	0.0048177577152354045	[849]	[741,749,1406,1191]	0	hSpCas9	negative selection	6965418
97177822	97177845	5	+	27260156	L33	viability	CATTTGTCAACCGATAGCCCTGG	RIOK2	ENSG00000058729	0.4258372473391431	[336]	[424,185,238,550]	8	hSpCas9	negative selection	7022413
97163149	97163172	5	-	27260156	L33	viability	GTCAGACGTCGATTGCAGAAAGG	RIOK2	ENSG00000058729	0.025784324373689105	[338]	[242,116,254,447]	0	hSpCas9	negative selection	7022414
97163118	97163141	5	-	27260156	L33	viability	ATATATTTACCAAGCAACGTAGG	RIOK2	ENSG00000058729	-0.10345062602161814	[1008]	[881,386,572,1018]	-2	hSpCas9	negative selection	7022415
97177735	97177758	5	+	27260156	L33	viability	ATTCTTTGCCAACACCCATCTGG	RIOK2	ENSG00000058729	0.13124320278150936	[296]	[214,158,243,312]	3	hSpCas9	negative selection	7086667
97177179	97177202	5	-	27260156	L33	viability	AACGCGATTATCATAAACATAGG	RIOK2	ENSG00000058729	-0.15825963087622175	[359]	[315,120,230,311]	-4	hSpCas9	negative selection	7086668
97177133	97177156	5	-	27260156	L33	viability	ATCTCGTCTCTCTGCCATGAAGG	RIOK2	ENSG00000058729	-0.15413665466527526	[849]	[835,307,498,672]	-4	hSpCas9	negative selection	7086669
97177822	97177845	5	+	27260156	K562	viability	CATTTGTCAACCGATAGCCCTGG	RIOK2	ENSG00000058729	0.05492552141038132	[336]	[567,272,132,288]	0	hSpCas9	negative selection	7143664
97163149	97163172	5	-	27260156	K562	viability	GTCAGACGTCGATTGCAGAAAGG	RIOK2	ENSG00000058729	-0.3929032544416293	[338]	[207,172,160,353]	-5	hSpCas9	negative selection	7143665
97163118	97163141	5	-	27260156	K562	viability	ATATATTTACCAAGCAACGTAGG	RIOK2	ENSG00000058729	-0.47939484290097867	[1008]	[524,755,783,512]	-5	hSpCas9	negative selection	7143666
97177735	97177758	5	+	27260156	K562	viability	ATTCTTTGCCAACACCCATCTGG	RIOK2	ENSG00000058729	0.5948777884101802	[296]	[383,293,243,633]	7	hSpCas9	negative selection	7207918
97177179	97177202	5	-	27260156	K562	viability	AACGCGATTATCATAAACATAGG	RIOK2	ENSG00000058729	0.3516098847980369	[359]	[218,393,198,758]	4	hSpCas9	negative selection	7207919
97177133	97177156	5	-	27260156	K562	viability	ATCTCGTCTCTCTGCCATGAAGG	RIOK2	ENSG00000058729	-0.014965137658273231	[849]	[666,1101,591,645]	0	hSpCas9	negative selection	7207920
97177822	97177845	5	+	27260156	HT29	viability	CATTTGTCAACCGATAGCCCTGG	RIOK2	ENSG00000058729	-0.08199133528319491	[336]	[444,357,354,388]	-2	hSpCas9	negative selection	7264915
97163149	97163172	5	-	27260156	HT29	viability	GTCAGACGTCGATTGCAGAAAGG	RIOK2	ENSG00000058729	-0.1408018691546985	[338]	[345,369,391,380]	-3	hSpCas9	negative selection	7264916
97163118	97163141	5	-	27260156	HT29	viability	ATATATTTACCAAGCAACGTAGG	RIOK2	ENSG00000058729	-0.6793855713627142	[1008]	[772,932,646,724]	-8	hSpCas9	negative selection	7264917
97177735	97177758	5	+	27260156	HT29	viability	ATTCTTTGCCAACACCCATCTGG	RIOK2	ENSG00000058729	0.021966845129171242	[296]	[452,331,330,352]	0	hSpCas9	negative selection	7329169
97177179	97177202	5	-	27260156	HT29	viability	AACGCGATTATCATAAACATAGG	RIOK2	ENSG00000058729	-0.20185310136448797	[359]	[557,282,352,335]	-4	hSpCas9	negative selection	7329170
97177133	97177156	5	-	27260156	HT29	viability	ATCTCGTCTCTCTGCCATGAAGG	RIOK2	ENSG00000058729	-0.17710012820099075	[849]	[852,1048,921,840]	-4	hSpCas9	negative selection	7329171
97177822	97177845	5	+	27260156	MHHES1	viability	CATTTGTCAACCGATAGCCCTGG	RIOK2	ENSG00000058729	-0.1450271093558928	[336]	[481,343,302,269]	-3	hSpCas9	negative selection	7386166
97163149	97163172	5	-	27260156	MHHES1	viability	GTCAGACGTCGATTGCAGAAAGG	RIOK2	ENSG00000058729	-0.3688310957166967	[338]	[364,283,325,224]	-6	hSpCas9	negative selection	7386167
97163118	97163141	5	-	27260156	MHHES1	viability	ATATATTTACCAAGCAACGTAGG	RIOK2	ENSG00000058729	-0.30647805691254193	[1008]	[840,675,1034,1039]	-5	hSpCas9	negative selection	7386168
97177735	97177758	5	+	27260156	MHHES1	viability	ATTCTTTGCCAACACCCATCTGG	RIOK2	ENSG00000058729	-0.6766131378578486	[296]	[245,270,149,181]	-8	hSpCas9	negative selection	7450420
97177179	97177202	5	-	27260156	MHHES1	viability	AACGCGATTATCATAAACATAGG	RIOK2	ENSG00000058729	-0.3495400425337234	[359]	[312,312,343,298]	-6	hSpCas9	negative selection	7450421
97177133	97177156	5	-	27260156	MHHES1	viability	ATCTCGTCTCTCTGCCATGAAGG	RIOK2	ENSG00000058729	-0.6830528781903484	[849]	[626,560,585,596]	-8	hSpCas9	negative selection	7450422
97177822	97177845	5	+	27260156	MEWO	viability	CATTTGTCAACCGATAGCCCTGG	RIOK2	ENSG00000058729	-0.04266613145907827	[336]	[438,299,204]	-1	hSpCas9	negative selection	7507417
97163149	97163172	5	-	27260156	MEWO	viability	GTCAGACGTCGATTGCAGAAAGG	RIOK2	ENSG00000058729	-0.28864909831291297	[338]	[300,236,248]	-6	hSpCas9	negative selection	7507418
97163118	97163141	5	-	27260156	MEWO	viability	ATATATTTACCAAGCAACGTAGG	RIOK2	ENSG00000058729	-0.15802129612839344	[1008]	[1178,734,688]	-3	hSpCas9	negative selection	7507419
97177735	97177758	5	+	27260156	MEWO	viability	ATTCTTTGCCAACACCCATCTGG	RIOK2	ENSG00000058729	0.11653129408921237	[296]	[451,270,209]	2	hSpCas9	negative selection	7571671
97177179	97177202	5	-	27260156	MEWO	viability	AACGCGATTATCATAAACATAGG	RIOK2	ENSG00000058729	-0.5784920365644995	[359]	[299,226,163]	-8	hSpCas9	negative selection	7571672
97177133	97177156	5	-	27260156	MEWO	viability	ATCTCGTCTCTCTGCCATGAAGG	RIOK2	ENSG00000058729	-0.36161659128782925	[849]	[513,678,642]	-7	hSpCas9	negative selection	7571673
97177822	97177845	5	+	27260156	LNCAPCLONEFGC	viability	CATTTGTCAACCGATAGCCCTGG	RIOK2	ENSG00000058729	0.0052095761106640825	[336]	[296,233,499,227]	0	hSpCas9	negative selection	7628668
97163149	97163172	5	-	27260156	LNCAPCLONEFGC	viability	GTCAGACGTCGATTGCAGAAAGG	RIOK2	ENSG00000058729	-0.0605765359631687	[338]	[232,333,319,292]	-1	hSpCas9	negative selection	7628669
97163118	97163141	5	-	27260156	LNCAPCLONEFGC	viability	ATATATTTACCAAGCAACGTAGG	RIOK2	ENSG00000058729	-0.31385246371467423	[1008]	[726,678,784,760]	-5	hSpCas9	negative selection	7628670
97177735	97177758	5	+	27260156	LNCAPCLONEFGC	viability	ATTCTTTGCCAACACCCATCTGG	RIOK2	ENSG00000058729	0.2683366222298058	[296]	[264,288,435,325]	4	hSpCas9	negative selection	7692922
97177179	97177202	5	-	27260156	LNCAPCLONEFGC	viability	AACGCGATTATCATAAACATAGG	RIOK2	ENSG00000058729	-0.2881883135535859	[359]	[272,293,265,232]	-4	hSpCas9	negative selection	7692923
97177133	97177156	5	-	27260156	LNCAPCLONEFGC	viability	ATCTCGTCTCTCTGCCATGAAGG	RIOK2	ENSG00000058729	-0.09306853965548911	[849]	[706,636,890,682]	-1	hSpCas9	negative selection	7692924
97177822	97177845	5	+	27260156	PANC0327	viability	CATTTGTCAACCGATAGCCCTGG	RIOK2	ENSG00000058729	-0.14350719360408148	[336]	[580,179,157,201]	-2	hSpCas9	negative selection	7749919
97163149	97163172	5	-	27260156	PANC0327	viability	GTCAGACGTCGATTGCAGAAAGG	RIOK2	ENSG00000058729	-0.5298376654265398	[338]	[167,184,242,237]	-6	hSpCas9	negative selection	7749920
97163118	97163141	5	-	27260156	PANC0327	viability	ATATATTTACCAAGCAACGTAGG	RIOK2	ENSG00000058729	-0.40300282846000035	[1008]	[752,343,557,1104]	-5	hSpCas9	negative selection	7749921
97177735	97177758	5	+	27260156	PANC0327	viability	ATTCTTTGCCAACACCCATCTGG	RIOK2	ENSG00000058729	-0.49345105020488633	[296]	[191,186,192,177]	-6	hSpCas9	negative selection	7814173
97177179	97177202	5	-	27260156	PANC0327	viability	AACGCGATTATCATAAACATAGG	RIOK2	ENSG00000058729	-0.4525274231889749	[359]	[343,168,187,250]	-6	hSpCas9	negative selection	7814174
97177133	97177156	5	-	27260156	PANC0327	viability	ATCTCGTCTCTCTGCCATGAAGG	RIOK2	ENSG00000058729	0.11632942446086803	[849]	[689,756,861,961]	1	hSpCas9	negative selection	7814175
97177822	97177845	5	+	27260156	NCIH2009	viability	CATTTGTCAACCGATAGCCCTGG	RIOK2	ENSG00000058729	0.24285140829007526	[336]	[623,377,684]	3	hSpCas9	negative selection	7871170
97163149	97163172	5	-	27260156	NCIH2009	viability	GTCAGACGTCGATTGCAGAAAGG	RIOK2	ENSG00000058729	-0.14477932663685733	[338]	[582,431,299]	-2	hSpCas9	negative selection	7871171
97163118	97163141	5	-	27260156	NCIH2009	viability	ATATATTTACCAAGCAACGTAGG	RIOK2	ENSG00000058729	-0.5838278633018668	[1008]	[1249,843,788]	-6	hSpCas9	negative selection	7871172
97177735	97177758	5	+	27260156	NCIH2009	viability	ATTCTTTGCCAACACCCATCTGG	RIOK2	ENSG00000058729	0.14221140168032842	[296]	[331,686,324]	2	hSpCas9	negative selection	7935424
97177179	97177202	5	-	27260156	NCIH2009	viability	AACGCGATTATCATAAACATAGG	RIOK2	ENSG00000058729	-0.1882129627115664	[359]	[529,172,642]	-3	hSpCas9	negative selection	7935425
97177133	97177156	5	-	27260156	NCIH2009	viability	ATCTCGTCTCTCTGCCATGAAGG	RIOK2	ENSG00000058729	-0.5314198402235384	[849]	[848,1040,574]	-6	hSpCas9	negative selection	7935426
97177822	97177845	5	+	27260156	NCIH1373	viability	CATTTGTCAACCGATAGCCCTGG	RIOK2	ENSG00000058729	0.40731650997590735	[336]	[751,402,605,71]	4	hSpCas9	negative selection	7992421
97163149	97163172	5	-	27260156	NCIH1373	viability	GTCAGACGTCGATTGCAGAAAGG	RIOK2	ENSG00000058729	-0.6033636699954783	[338]	[223,330,170,68]	-5	hSpCas9	negative selection	7992422
97163118	97163141	5	-	27260156	NCIH1373	viability	ATATATTTACCAAGCAACGTAGG	RIOK2	ENSG00000058729	-0.872908389767784	[1008]	[478,608,521,223]	-7	hSpCas9	negative selection	7992423
97177735	97177758	5	+	27260156	NCIH1373	viability	ATTCTTTGCCAACACCCATCTGG	RIOK2	ENSG00000058729	0.26478984752689	[296]	[492,466,447,47]	2	hSpCas9	negative selection	8056675
97177179	97177202	5	-	27260156	NCIH1373	viability	AACGCGATTATCATAAACATAGG	RIOK2	ENSG00000058729	-0.14356216929382937	[359]	[575,115,340,129]	-1	hSpCas9	negative selection	8056676
97177133	97177156	5	-	27260156	NCIH1373	viability	ATCTCGTCTCTCTGCCATGAAGG	RIOK2	ENSG00000058729	-0.8278318822388314	[849]	[616,408,469,179]	-7	hSpCas9	negative selection	8056677
97177822	97177845	5	+	27260156	PATU8902	viability	CATTTGTCAACCGATAGCCCTGG	RIOK2	ENSG00000058729	0.5201911936533985	[336]	[832,736,553,580]	5	hSpCas9	negative selection	8113672
97163149	97163172	5	-	27260156	PATU8902	viability	GTCAGACGTCGATTGCAGAAAGG	RIOK2	ENSG00000058729	-0.2985959396351756	[338]	[201,181,608,495]	-3	hSpCas9	negative selection	8113673
97163118	97163141	5	-	27260156	PATU8902	viability	ATATATTTACCAAGCAACGTAGG	RIOK2	ENSG00000058729	-1.0251308037171516	[1008]	[543,1085,317,937]	-7	hSpCas9	negative selection	8113674
97177735	97177758	5	+	27260156	PATU8902	viability	ATTCTTTGCCAACACCCATCTGG	RIOK2	ENSG00000058729	-0.11963873675740178	[296]	[349,924,106,187]	-1	hSpCas9	negative selection	8177926
97177179	97177202	5	-	27260156	PATU8902	viability	AACGCGATTATCATAAACATAGG	RIOK2	ENSG00000058729	-1.0819540382953652	[359]	[411,248,104,207]	-7	hSpCas9	negative selection	8177927
97177133	97177156	5	-	27260156	PATU8902	viability	ATCTCGTCTCTCTGCCATGAAGG	RIOK2	ENSG00000058729	-1.8918365294303237	[849]	[327,481,193,299]	-9	hSpCas9	negative selection	8177928
97177822	97177845	5	+	27260156	PANC1	viability	CATTTGTCAACCGATAGCCCTGG	RIOK2	ENSG00000058729	-0.2975983086436975	[336]	[80,308,322,242]	-5	hSpCas9	negative selection	8234923
97163149	97163172	5	-	27260156	PANC1	viability	GTCAGACGTCGATTGCAGAAAGG	RIOK2	ENSG00000058729	-0.391442832344313	[338]	[252,255,198,187]	-6	hSpCas9	negative selection	8234924
97163118	97163141	5	-	27260156	PANC1	viability	ATATATTTACCAAGCAACGTAGG	RIOK2	ENSG00000058729	-0.7479059902588403	[1008]	[400,599,593,485]	-8	hSpCas9	negative selection	8234925
97177735	97177758	5	+	27260156	PANC1	viability	ATTCTTTGCCAACACCCATCTGG	RIOK2	ENSG00000058729	-0.18836130090699033	[296]	[269,196,187,228]	-3	hSpCas9	negative selection	8299177
97177179	97177202	5	-	27260156	PANC1	viability	AACGCGATTATCATAAACATAGG	RIOK2	ENSG00000058729	-0.043346971356254316	[359]	[348,293,325,234]	0	hSpCas9	negative selection	8299178
97177133	97177156	5	-	27260156	PANC1	viability	ATCTCGTCTCTCTGCCATGAAGG	RIOK2	ENSG00000058729	-0.487632994211816	[849]	[511,699,371,524]	-6	hSpCas9	negative selection	8299179
97177822	97177845	5	+	27260156	PANC0813	viability	CATTTGTCAACCGATAGCCCTGG	RIOK2	ENSG00000058729	-0.2620981740463729	[336]	[369,366,270,315]	-4	hSpCas9	negative selection	8356174
97163149	97163172	5	-	27260156	PANC0813	viability	GTCAGACGTCGATTGCAGAAAGG	RIOK2	ENSG00000058729	-0.5838040127744093	[338]	[285,282,263,232]	-7	hSpCas9	negative selection	8356175
97163118	97163141	5	-	27260156	PANC0813	viability	ATATATTTACCAAGCAACGTAGG	RIOK2	ENSG00000058729	-0.5477273770265599	[1008]	[923,894,769,670]	-7	hSpCas9	negative selection	8356176
97177735	97177758	5	+	27260156	PANC0813	viability	ATTCTTTGCCAACACCCATCTGG	RIOK2	ENSG00000058729	0.016838297340560304	[296]	[394,515,268,240]	0	hSpCas9	negative selection	8420428
97177179	97177202	5	-	27260156	PANC0813	viability	AACGCGATTATCATAAACATAGG	RIOK2	ENSG00000058729	-0.7128602437039953	[359]	[219,228,314,263]	-7	hSpCas9	negative selection	8420429
97177133	97177156	5	-	27260156	PANC0813	viability	ATCTCGTCTCTCTGCCATGAAGG	RIOK2	ENSG00000058729	-0.6970123583358186	[849]	[623,587,542,702]	-7	hSpCas9	negative selection	8420430
97177822	97177845	5	+	27260156	RDES	viability	CATTTGTCAACCGATAGCCCTGG	RIOK2	ENSG00000058729	-0.001920828659712659	[336]	[285,377,413,499]	0	hSpCas9	negative selection	8477425
97163149	97163172	5	-	27260156	RDES	viability	GTCAGACGTCGATTGCAGAAAGG	RIOK2	ENSG00000058729	-0.2210667632422112	[338]	[260,284,356,466]	-4	hSpCas9	negative selection	8477426
97163118	97163141	5	-	27260156	RDES	viability	ATATATTTACCAAGCAACGTAGG	RIOK2	ENSG00000058729	-0.7109348913898135	[1008]	[563,698,791,809]	-8	hSpCas9	negative selection	8477427
97177735	97177758	5	+	27260156	RDES	viability	ATTCTTTGCCAACACCCATCTGG	RIOK2	ENSG00000058729	-0.029123742828823684	[296]	[291,301,259,510]	0	hSpCas9	negative selection	8541679
97177179	97177202	5	-	27260156	RDES	viability	AACGCGATTATCATAAACATAGG	RIOK2	ENSG00000058729	-0.48444817638290816	[359]	[272,218,349,355]	-7	hSpCas9	negative selection	8541680
97177133	97177156	5	-	27260156	RDES	viability	ATCTCGTCTCTCTGCCATGAAGG	RIOK2	ENSG00000058729	-0.2853160618144138	[849]	[740,795,804,862]	-5	hSpCas9	negative selection	8541681
97177822	97177845	5	+	27260156	PC3	viability	CATTTGTCAACCGATAGCCCTGG	RIOK2	ENSG00000058729	0.006832549204949689	[336]	[251,411,428,283]	0	hSpCas9	negative selection	8598676
97163149	97163172	5	-	27260156	PC3	viability	GTCAGACGTCGATTGCAGAAAGG	RIOK2	ENSG00000058729	0.030384319065911047	[338]	[177,300,876,276]	0	hSpCas9	negative selection	8598677
97163118	97163141	5	-	27260156	PC3	viability	ATATATTTACCAAGCAACGTAGG	RIOK2	ENSG00000058729	-0.27581700096557504	[1008]	[479,766,1124,1161]	-6	hSpCas9	negative selection	8598678
97177735	97177758	5	+	27260156	PC3	viability	ATTCTTTGCCAACACCCATCTGG	RIOK2	ENSG00000058729	0.30070412703090577	[296]	[300,399,462,309]	6	hSpCas9	negative selection	8662930
97177179	97177202	5	-	27260156	PC3	viability	AACGCGATTATCATAAACATAGG	RIOK2	ENSG00000058729	-0.11470840164038554	[359]	[218,329,758,193]	-3	hSpCas9	negative selection	8662931
97177133	97177156	5	-	27260156	PC3	viability	ATCTCGTCTCTCTGCCATGAAGG	RIOK2	ENSG00000058729	-0.05384956100895577	[849]	[663,885,970,761]	-1	hSpCas9	negative selection	8662932
97177822	97177845	5	+	27260156	PATU8988T	viability	CATTTGTCAACCGATAGCCCTGG	RIOK2	ENSG00000058729	-0.715111309584161	[336]	[210,217,135,233]	-8	hSpCas9	negative selection	8719927
97163149	97163172	5	-	27260156	PATU8988T	viability	GTCAGACGTCGATTGCAGAAAGG	RIOK2	ENSG00000058729	-0.1522355087602304	[338]	[335,307,251,283]	-3	hSpCas9	negative selection	8719928
97163118	97163141	5	-	27260156	PATU8988T	viability	ATATATTTACCAAGCAACGTAGG	RIOK2	ENSG00000058729	-0.5291324854219006	[1008]	[581,653,570,913]	-7	hSpCas9	negative selection	8719929
97177735	97177758	5	+	27260156	PATU8988T	viability	ATTCTTTGCCAACACCCATCTGG	RIOK2	ENSG00000058729	-0.0346294582519453	[296]	[288,194,491,120]	0	hSpCas9	negative selection	8784181
97177179	97177202	5	-	27260156	PATU8988T	viability	AACGCGATTATCATAAACATAGG	RIOK2	ENSG00000058729	-0.23153039251313068	[359]	[232,472,131,371]	-4	hSpCas9	negative selection	8784182
97177133	97177156	5	-	27260156	PATU8988T	viability	ATCTCGTCTCTCTGCCATGAAGG	RIOK2	ENSG00000058729	-0.15052180691187833	[849]	[687,894,676,712]	-3	hSpCas9	negative selection	8784183
97177822	97177845	5	+	27260156	T47D	viability	CATTTGTCAACCGATAGCCCTGG	RIOK2	ENSG00000058729	-0.239775100428666	[336]	[340,264,329,401]	-5	hSpCas9	negative selection	8841178
97163149	97163172	5	-	27260156	T47D	viability	GTCAGACGTCGATTGCAGAAAGG	RIOK2	ENSG00000058729	0.17210207618618728	[338]	[396,452,385,546]	3	hSpCas9	negative selection	8841179
97163118	97163141	5	-	27260156	T47D	viability	ATATATTTACCAAGCAACGTAGG	RIOK2	ENSG00000058729	-0.19985832012340565	[1008]	[1035,876,1041,1154]	-4	hSpCas9	negative selection	8841180
97177735	97177758	5	+	27260156	T47D	viability	ATTCTTTGCCAACACCCATCTGG	RIOK2	ENSG00000058729	0.16589065100168282	[296]	[459,370,277,448]	3	hSpCas9	negative selection	8905432
97177179	97177202	5	-	27260156	T47D	viability	AACGCGATTATCATAAACATAGG	RIOK2	ENSG00000058729	-0.15927064317319672	[359]	[378,420,322,375]	-4	hSpCas9	negative selection	8905433
97177133	97177156	5	-	27260156	T47D	viability	ATCTCGTCTCTCTGCCATGAAGG	RIOK2	ENSG00000058729	-0.014531544366537918	[849]	[958,877,1022,1071]	0	hSpCas9	negative selection	8905434
97177822	97177845	5	+	27260156	SU8686	viability	CATTTGTCAACCGATAGCCCTGG	RIOK2	ENSG00000058729	-0.20387817204992087	[336]	[205,359,277,318]	-4	hSpCas9	negative selection	8962429
97163149	97163172	5	-	27260156	SU8686	viability	GTCAGACGTCGATTGCAGAAAGG	RIOK2	ENSG00000058729	-0.3448126588555325	[338]	[239,222,257,358]	-5	hSpCas9	negative selection	8962430
97163118	97163141	5	-	27260156	SU8686	viability	ATATATTTACCAAGCAACGTAGG	RIOK2	ENSG00000058729	-0.5695804351984368	[1008]	[722,539,809,625]	-7	hSpCas9	negative selection	8962431
97177735	97177758	5	+	27260156	SU8686	viability	ATTCTTTGCCAACACCCATCTGG	RIOK2	ENSG00000058729	0.20404485632244262	[296]	[238,250,349,575]	3	hSpCas9	negative selection	9026683
97177179	97177202	5	-	27260156	SU8686	viability	AACGCGATTATCATAAACATAGG	RIOK2	ENSG00000058729	-0.6048841616573609	[359]	[240,252,197,241]	-7	hSpCas9	negative selection	9026684
97177133	97177156	5	-	27260156	SU8686	viability	ATCTCGTCTCTCTGCCATGAAGG	RIOK2	ENSG00000058729	-0.5006893249532581	[849]	[391,578,733,722]	-7	hSpCas9	negative selection	9026685
97177822	97177845	5	+	27260156	SKES1	viability	CATTTGTCAACCGATAGCCCTGG	RIOK2	ENSG00000058729	0.04316551088152554	[336]	[416,322,350,302]	1	hSpCas9	negative selection	9083680
97163149	97163172	5	-	27260156	SKES1	viability	GTCAGACGTCGATTGCAGAAAGG	RIOK2	ENSG00000058729	0.046220595041590484	[338]	[431,382,256,338]	1	hSpCas9	negative selection	9083681
97163118	97163141	5	-	27260156	SKES1	viability	ATATATTTACCAAGCAACGTAGG	RIOK2	ENSG00000058729	-0.18715290685272257	[1008]	[804,1117,957,685]	-4	hSpCas9	negative selection	9083682
97177735	97177758	5	+	27260156	SKES1	viability	ATTCTTTGCCAACACCCATCTGG	RIOK2	ENSG00000058729	0.15908261775299226	[296]	[504,284,282,272]	3	hSpCas9	negative selection	9147934
97177179	97177202	5	-	27260156	SKES1	viability	AACGCGATTATCATAAACATAGG	RIOK2	ENSG00000058729	-0.18761789832396947	[359]	[505,296,267,222]	-4	hSpCas9	negative selection	9147935
97177133	97177156	5	-	27260156	SKES1	viability	ATCTCGTCTCTCTGCCATGAAGG	RIOK2	ENSG00000058729	-0.4275974915722844	[849]	[577,749,637,563]	-7	hSpCas9	negative selection	9147936
97177822	97177845	5	+	27260156	TOV112D	viability	CATTTGTCAACCGATAGCCCTGG	RIOK2	ENSG00000058729	-0.06539532173249063	[336]	[339,323,248,376]	-1	hSpCas9	negative selection	9204931
97163149	97163172	5	-	27260156	TOV112D	viability	GTCAGACGTCGATTGCAGAAAGG	RIOK2	ENSG00000058729	-0.2502889631368642	[338]	[247,460,245,227]	-5	hSpCas9	negative selection	9204932
97163118	97163141	5	-	27260156	TOV112D	viability	ATATATTTACCAAGCAACGTAGG	RIOK2	ENSG00000058729	-0.32124081015349215	[1008]	[828,791,998,616]	-6	hSpCas9	negative selection	9204933
97177735	97177758	5	+	27260156	TOV112D	viability	ATTCTTTGCCAACACCCATCTGG	RIOK2	ENSG00000058729	-0.04858538124952072	[296]	[312,307,352,185]	-1	hSpCas9	negative selection	9269185
97177179	97177202	5	-	27260156	TOV112D	viability	AACGCGATTATCATAAACATAGG	RIOK2	ENSG00000058729	-0.08050463460519225	[359]	[222,522,265,384]	-1	hSpCas9	negative selection	9269186
97177133	97177156	5	-	27260156	TOV112D	viability	ATCTCGTCTCTCTGCCATGAAGG	RIOK2	ENSG00000058729	-0.29693229368939167	[849]	[588,920,685,623]	-5	hSpCas9	negative selection	9269187
97177822	97177845	5	+	27260156	TC71	viability	CATTTGTCAACCGATAGCCCTGG	RIOK2	ENSG00000058729	-0.21364718112634973	[336]	[379,303,265,294]	-5	hSpCas9	negative selection	9326182
97163149	97163172	5	-	27260156	TC71	viability	GTCAGACGTCGATTGCAGAAAGG	RIOK2	ENSG00000058729	-0.13792092251700083	[338]	[338,250,393,334]	-4	hSpCas9	negative selection	9326183
97163118	97163141	5	-	27260156	TC71	viability	ATATATTTACCAAGCAACGTAGG	RIOK2	ENSG00000058729	-0.34120557696748766	[1008]	[958,722,865,864]	-7	hSpCas9	negative selection	9326184
97177735	97177758	5	+	27260156	TC71	viability	ATTCTTTGCCAACACCCATCTGG	RIOK2	ENSG00000058729	0.24798986567272296	[296]	[346,390,389,384]	6	hSpCas9	negative selection	9390436
97177179	97177202	5	-	27260156	TC71	viability	AACGCGATTATCATAAACATAGG	RIOK2	ENSG00000058729	-0.18484367137368463	[359]	[415,335,292,310]	-5	hSpCas9	negative selection	9390437
97177133	97177156	5	-	27260156	TC71	viability	ATCTCGTCTCTCTGCCATGAAGG	RIOK2	ENSG00000058729	-0.18364996409778522	[849]	[765,732,798,918]	-5	hSpCas9	negative selection	9390438
97177822	97177845	5	+	27260156	TC32	viability	CATTTGTCAACCGATAGCCCTGG	RIOK2	ENSG00000058729	0.06112164795814429	[336]	[397,231,298,398]	1	hSpCas9	negative selection	9447433
97163149	97163172	5	-	27260156	TC32	viability	GTCAGACGTCGATTGCAGAAAGG	RIOK2	ENSG00000058729	-0.4431753558479029	[338]	[218,170,412,173]	-7	hSpCas9	negative selection	9447434
97163118	97163141	5	-	27260156	TC32	viability	ATATATTTACCAAGCAACGTAGG	RIOK2	ENSG00000058729	-0.6885182380359363	[1008]	[639,448,742,555]	-8	hSpCas9	negative selection	9447435
97177735	97177758	5	+	27260156	TC32	viability	ATTCTTTGCCAACACCCATCTGG	RIOK2	ENSG00000058729	-0.0812078635704957	[296]	[200,245,260,349]	-1	hSpCas9	negative selection	9511687
97177179	97177202	5	-	27260156	TC32	viability	AACGCGATTATCATAAACATAGG	RIOK2	ENSG00000058729	-0.36946759167962795	[359]	[238,203,294,327]	-6	hSpCas9	negative selection	9511688
97177133	97177156	5	-	27260156	TC32	viability	ATCTCGTCTCTCTGCCATGAAGG	RIOK2	ENSG00000058729	-0.44908697313394	[849]	[637,419,742,586]	-7	hSpCas9	negative selection	9511689
97167953	97167976	5	-	27869803	HPAFII	viability after 27 days	GATGTGGAGGTTTCTGCCAGTGG	RIOK2	ENSG00000058729	-1.8537792591489564	[129]	[31,7,NaN]	-8	hSpCas9	negative selection	9592950
97171363	97171386	5	+	27869803	HPAFII	viability after 27 days	CTGATGCAGGATCTTCAACATGG	RIOK2	ENSG00000058729	-2.193629262033581	[809]	[127,63,NaN]	-8	hSpCas9	negative selection	9592951
97177822	97177845	5	+	27869803	HPAFII	viability after 27 days	CATTTGTCAACCGATAGCCCTGG	RIOK2	ENSG00000058729	-5.021236005000519	[145]	[3,0,NaN]	-9	hSpCas9	negative selection	9592952
97179113	97179136	5	+	27869803	HPAFII	viability after 27 days	ACAGCCACCATGTTTAAGGCTGG	RIOK2	ENSG00000058729	-3.663641036817135	[251]	[4,14,NaN]	-9	hSpCas9	negative selection	9592953
97183095	97183118	5	+	27869803	HPAFII	viability after 27 days	GAAGGGAGAACAGGAACGGCGGG	RIOK2	ENSG00000058729	-0.5238583735080632	[134]	[20,72,NaN]	-4	hSpCas9	negative selection	9592954
97167953	97167976	5	-	27869803	HPAFII	viability after 15 days	GATGTGGAGGTTTCTGCCAGTGG	RIOK2	ENSG00000058729	-1.6403350492970494	[129]	[58,35,NaN]	-8	hSpCas9	negative selection	9675399
97171363	97171386	5	+	27869803	HPAFII	viability after 15 days	CTGATGCAGGATCTTCAACATGG	RIOK2	ENSG00000058729	-2.0865582880115565	[809]	[302,143,NaN]	-9	hSpCas9	negative selection	9675400
97177822	97177845	5	+	27869803	HPAFII	viability after 15 days	CATTTGTCAACCGATAGCCCTGG	RIOK2	ENSG00000058729	-2.6857628436416663	[145]	[61,0,NaN]	-9	hSpCas9	negative selection	9675401
97179113	97179136	5	+	27869803	HPAFII	viability after 15 days	ACAGCCACCATGTTTAAGGCTGG	RIOK2	ENSG00000058729	-2.6394244674599756	[251]	[40,44,NaN]	-9	hSpCas9	negative selection	9675402
97183095	97183118	5	+	27869803	HPAFII	viability after 15 days	GAAGGGAGAACAGGAACGGCGGG	RIOK2	ENSG00000058729	-0.9766508234861236	[134]	[16,108,NaN]	-7	hSpCas9	negative selection	9675403
97167953	97167976	5	-	27869803	ASPC1	viability after 36 days	GATGTGGAGGTTTCTGCCAGTGG	RIOK2	ENSG00000058729	1.201540073202345	[313]	[855,19,9]	9	hSpCas9	negative selection	9757848
97171363	97171386	5	+	27869803	ASPC1	viability after 36 days	CTGATGCAGGATCTTCAACATGG	RIOK2	ENSG00000058729	-0.2617548869001278	[1858]	[354,470,721]	-3	hSpCas9	negative selection	9757849
97177822	97177845	5	+	27869803	ASPC1	viability after 36 days	CATTTGTCAACCGATAGCCCTGG	RIOK2	ENSG00000058729	-1.8943414492946566	[403]	[30,45,35]	-9	hSpCas9	negative selection	9757850
97179113	97179136	5	+	27869803	ASPC1	viability after 36 days	ACAGCCACCATGTTTAAGGCTGG	RIOK2	ENSG00000058729	-1.101866027639212	[547]	[69,201,11]	-8	hSpCas9	negative selection	9757851
97183095	97183118	5	+	27869803	ASPC1	viability after 36 days	GAAGGGAGAACAGGAACGGCGGG	RIOK2	ENSG00000058729	0.08956518237535072	[249]	[58,235,1]	0	hSpCas9	negative selection	9757852
97167953	97167976	5	-	27869803	PATU8988S	viability after 35 days	GATGTGGAGGTTTCTGCCAGTGG	RIOK2	ENSG00000058729	-4.710325036954641	[324]	[4,4,NaN]	-9	hSpCas9	negative selection	9840297
97171363	97171386	5	+	27869803	PATU8988S	viability after 35 days	CTGATGCAGGATCTTCAACATGG	RIOK2	ENSG00000058729	-1.366799084917627	[1600]	[259,239,NaN]	-8	hSpCas9	negative selection	9840298
97177822	97177845	5	+	27869803	PATU8988S	viability after 35 days	CATTTGTCAACCGATAGCCCTGG	RIOK2	ENSG00000058729	-1.0474698158003672	[307]	[66,52,NaN]	-7	hSpCas9	negative selection	9840299
97179113	97179136	5	+	27869803	PATU8988S	viability after 35 days	ACAGCCACCATGTTTAAGGCTGG	RIOK2	ENSG00000058729	-1.8185446426219607	[459]	[62,41,NaN]	-8	hSpCas9	negative selection	9840300
97183095	97183118	5	+	27869803	PATU8988S	viability after 35 days	GAAGGGAGAACAGGAACGGCGGG	RIOK2	ENSG00000058729	-0.12366976449665379	[183]	[75,59,NaN]	-1	hSpCas9	negative selection	9840301
97167953	97167976	5	-	27869803	PATU8988S	viability after 31 days	GATGTGGAGGTTTCTGCCAGTGG	RIOK2	ENSG00000058729	-5.138016277475362	[324]	[4,1,NaN]	-9	hSpCas9	negative selection	9922746
97171363	97171386	5	+	27869803	PATU8988S	viability after 31 days	CTGATGCAGGATCTTCAACATGG	RIOK2	ENSG00000058729	-1.7612500703945193	[1600]	[186,189,NaN]	-9	hSpCas9	negative selection	9922747
97177822	97177845	5	+	27869803	PATU8988S	viability after 31 days	CATTTGTCAACCGATAGCCCTGG	RIOK2	ENSG00000058729	-1.5661078634247936	[307]	[22,64,NaN]	-8	hSpCas9	negative selection	9922748
97179113	97179136	5	+	27869803	PATU8988S	viability after 31 days	ACAGCCACCATGTTTAAGGCTGG	RIOK2	ENSG00000058729	-1.3586254466264667	[459]	[100,33,NaN]	-8	hSpCas9	negative selection	9922749
97183095	97183118	5	+	27869803	PATU8988S	viability after 31 days	GAAGGGAGAACAGGAACGGCGGG	RIOK2	ENSG00000058729	-0.11575475064551366	[183]	[28,116,NaN]	-1	hSpCas9	negative selection	9922750
97167953	97167976	5	-	27869803	HPAFII	viability after 35 days	GATGTGGAGGTTTCTGCCAGTGG	RIOK2	ENSG00000058729	-1.7965596101071268	[129]	[25,10,NaN]	-7	hSpCas9	negative selection	10005195
97171363	97171386	5	+	27869803	HPAFII	viability after 35 days	CTGATGCAGGATCTTCAACATGG	RIOK2	ENSG00000058729	-1.9506935757438673	[809]	[146,59,NaN]	-7	hSpCas9	negative selection	10005196
97177822	97177845	5	+	27869803	HPAFII	viability after 35 days	CATTTGTCAACCGATAGCCCTGG	RIOK2	ENSG00000058729	-2.375746644150862	[145]	[25,0,NaN]	-8	hSpCas9	negative selection	10005197
97179113	97179136	5	+	27869803	HPAFII	viability after 35 days	ACAGCCACCATGTTTAAGGCTGG	RIOK2	ENSG00000058729	-3.3894703096152874	[251]	[6,17,NaN]	-8	hSpCas9	negative selection	10005198
97183095	97183118	5	+	27869803	HPAFII	viability after 35 days	GAAGGGAGAACAGGAACGGCGGG	RIOK2	ENSG00000058729	-1.6244499847378426	[134]	[0,45,NaN]	-7	hSpCas9	negative selection	10005199
97167953	97167976	5	-	27869803	HPAFII	viability after 31 days	GATGTGGAGGTTTCTGCCAGTGG	RIOK2	ENSG00000058729	-1.738492300771172	[129]	[29,12,NaN]	-7	hSpCas9	negative selection	10087644
97171363	97171386	5	+	27869803	HPAFII	viability after 31 days	CTGATGCAGGATCTTCAACATGG	RIOK2	ENSG00000058729	-2.335981417295794	[809]	[101,76,NaN]	-8	hSpCas9	negative selection	10087645
97177822	97177845	5	+	27869803	HPAFII	viability after 31 days	CATTTGTCAACCGATAGCCCTGG	RIOK2	ENSG00000058729	-2.9799248222301316	[145]	[18,0,NaN]	-8	hSpCas9	negative selection	10087646
97179113	97179136	5	+	27869803	HPAFII	viability after 31 days	ACAGCCACCATGTTTAAGGCTGG	RIOK2	ENSG00000058729	-3.4005168604990192	[251]	[10,15,NaN]	-9	hSpCas9	negative selection	10087647
97183095	97183118	5	+	27869803	HPAFII	viability after 31 days	GAAGGGAGAACAGGAACGGCGGG	RIOK2	ENSG00000058729	-0.8282458920097492	[134]	[12,74,NaN]	-5	hSpCas9	negative selection	10087648
97167774	97167797	5	-	28162770	P31FUJ	viability	GAACTGTCTAGAAGAATCAGAGG	RIOK2	ENSG00000058729	-0.853947041442181	[322]	[209]	-6	hSpCas9	negative selection	10225509
97171196	97171219	5	+	28162770	P31FUJ	viability	AAGTACGTACCACTCAGCATTGG	RIOK2	ENSG00000058729	-0.7515475015594708	[840]	[586]	-5	hSpCas9	negative selection	10225510
97167554	97167577	5	-	28162770	P31FUJ	viability	GATGGTCAGAGAGTTCAAGGAGG	RIOK2	ENSG00000058729	-0.805890604847243	[362]	[243]	-6	hSpCas9	negative selection	10225511
97179117	97179140	5	-	28162770	P31FUJ	viability	ATAGCCAGCCTTAAACATGGTGG	RIOK2	ENSG00000058729	-0.7223866570582764	[138]	[98]	-5	hSpCas9	negative selection	10225512
97177743	97177766	5	-	28162770	P31FUJ	viability	GTTGGAAACCAGATGGGTGTTGG	RIOK2	ENSG00000058729	-2.71822903158462	[27]	[4]	-9	hSpCas9	negative selection	10225513
97167953	97167976	5	-	28162770	P31FUJ	viability	GATGTGGAGGTTTCTGCCAGTGG	RIOK2	ENSG00000058729	-1.7275668961639563	[123]	[43]	-8	hSpCas9	negative selection	10225514
97167494	97167517	5	+	28162770	P31FUJ	viability	GACGACAAGGCAATTAGATGAGG	RIOK2	ENSG00000058729	-1.7242780762574255	[238]	[84]	-8	hSpCas9	negative selection	10225515
97183125	97183148	5	-	28162770	P31FUJ	viability	TGACTTCAGGGTCTTGACCGCGG	RIOK2	ENSG00000058729	-3.7705995970568544	[661]	[56]	-9	hSpCas9	negative selection	10225516
97177164	97177187	5	-	28162770	P31FUJ	viability	AACATAGGCACAATGTGTCATGG	RIOK2	ENSG00000058729	0.7358714613917159	[418]	[819]	8	hSpCas9	negative selection	10225517
97171221	97171244	5	+	28162770	P31FUJ	viability	TGAGAAGTTGAAACCATCTGTGG	RIOK2	ENSG00000058729	-2.294517988900794	[596]	[142]	-8	hSpCas9	negative selection	10225518
97167774	97167797	5	-	28162770	TF1	viability	GAACTGTCTAGAAGAATCAGAGG	RIOK2	ENSG00000058729	NaN	[NaN]	[164]	1	hSpCas9	negative selection	10394875
97171196	97171219	5	+	28162770	TF1	viability	AAGTACGTACCACTCAGCATTGG	RIOK2	ENSG00000058729	NaN	[NaN]	[168]	1	hSpCas9	negative selection	10394876
97167554	97167577	5	-	28162770	TF1	viability	GATGGTCAGAGAGTTCAAGGAGG	RIOK2	ENSG00000058729	NaN	[NaN]	[34]	1	hSpCas9	negative selection	10394877
97179117	97179140	5	-	28162770	TF1	viability	ATAGCCAGCCTTAAACATGGTGG	RIOK2	ENSG00000058729	NaN	[NaN]	[59]	1	hSpCas9	negative selection	10394878
97177743	97177766	5	-	28162770	TF1	viability	GTTGGAAACCAGATGGGTGTTGG	RIOK2	ENSG00000058729	NaN	[NaN]	[0]	1	hSpCas9	negative selection	10394879
97167953	97167976	5	-	28162770	TF1	viability	GATGTGGAGGTTTCTGCCAGTGG	RIOK2	ENSG00000058729	NaN	[NaN]	[68]	1	hSpCas9	negative selection	10394880
97167494	97167517	5	+	28162770	TF1	viability	GACGACAAGGCAATTAGATGAGG	RIOK2	ENSG00000058729	NaN	[NaN]	[31]	1	hSpCas9	negative selection	10394881
97183125	97183148	5	-	28162770	TF1	viability	TGACTTCAGGGTCTTGACCGCGG	RIOK2	ENSG00000058729	NaN	[NaN]	[176]	1	hSpCas9	negative selection	10394882
97177164	97177187	5	-	28162770	TF1	viability	AACATAGGCACAATGTGTCATGG	RIOK2	ENSG00000058729	NaN	[NaN]	[270]	1	hSpCas9	negative selection	10394883
97171221	97171244	5	+	28162770	TF1	viability	TGAGAAGTTGAAACCATCTGTGG	RIOK2	ENSG00000058729	NaN	[NaN]	[136]	1	hSpCas9	negative selection	10394884
97167774	97167797	5	-	28162770	SKM1	viability	GAACTGTCTAGAAGAATCAGAGG	RIOK2	ENSG00000058729	-0.19581653457433634	[91]	[141]	-2	hSpCas9	negative selection	10564241
97171196	97171219	5	+	28162770	SKM1	viability	AAGTACGTACCACTCAGCATTGG	RIOK2	ENSG00000058729	-1.5787305470096418	[195]	[115]	-8	hSpCas9	negative selection	10564242
97167554	97167577	5	-	28162770	SKM1	viability	GATGGTCAGAGAGTTCAAGGAGG	RIOK2	ENSG00000058729	0.3271417412838038	[100]	[223]	3	hSpCas9	negative selection	10564243
97179117	97179140	5	-	28162770	SKM1	viability	ATAGCCAGCCTTAAACATGGTGG	RIOK2	ENSG00000058729	-2.6699986045769557	[53]	[14]	-9	hSpCas9	negative selection	10564244
97177743	97177766	5	-	28162770	SKM1	viability	GTTGGAAACCAGATGGGTGTTGG	RIOK2	ENSG00000058729	-3.6293566200796095	[6]	[0]	-9	hSpCas9	negative selection	10564245
97167953	97167976	5	-	28162770	SKM1	viability	GATGTGGAGGTTTCTGCCAGTGG	RIOK2	ENSG00000058729	-0.9701003370111393	[40]	[36]	-6	hSpCas9	negative selection	10564246
97167494	97167517	5	+	28162770	SKM1	viability	GACGACAAGGCAATTAGATGAGG	RIOK2	ENSG00000058729	-0.4409115306664994	[42]	[55]	-4	hSpCas9	negative selection	10564247
97183125	97183148	5	-	28162770	SKM1	viability	TGACTTCAGGGTCTTGACCGCGG	RIOK2	ENSG00000058729	-3.6799826931495776	[144]	[19]	-9	hSpCas9	negative selection	10564248
97177164	97177187	5	-	28162770	SKM1	viability	AACATAGGCACAATGTGTCATGG	RIOK2	ENSG00000058729	0.6754979614488112	[101]	[287]	6	hSpCas9	negative selection	10564249
97171221	97171244	5	+	28162770	SKM1	viability	TGAGAAGTTGAAACCATCTGTGG	RIOK2	ENSG00000058729	-0.7734215175769439	[145]	[150]	-5	hSpCas9	negative selection	10564250
97167774	97167797	5	-	28162770	SKM1	viability	GAACTGTCTAGAAGAATCAGAGG	RIOK2	ENSG00000058729	-0.19581653457433634	[91]	[141]	-2	hSpCas9	negative selection	10733607
97171196	97171219	5	+	28162770	SKM1	viability	AAGTACGTACCACTCAGCATTGG	RIOK2	ENSG00000058729	-1.5787305470096418	[195]	[115]	-8	hSpCas9	negative selection	10733608
97167554	97167577	5	-	28162770	SKM1	viability	GATGGTCAGAGAGTTCAAGGAGG	RIOK2	ENSG00000058729	0.3271417412838038	[100]	[223]	3	hSpCas9	negative selection	10733609
97179117	97179140	5	-	28162770	SKM1	viability	ATAGCCAGCCTTAAACATGGTGG	RIOK2	ENSG00000058729	-2.6699986045769557	[53]	[14]	-9	hSpCas9	negative selection	10733610
97177743	97177766	5	-	28162770	SKM1	viability	GTTGGAAACCAGATGGGTGTTGG	RIOK2	ENSG00000058729	-3.6293566200796095	[6]	[0]	-9	hSpCas9	negative selection	10733611
97167953	97167976	5	-	28162770	SKM1	viability	GATGTGGAGGTTTCTGCCAGTGG	RIOK2	ENSG00000058729	-0.9701003370111393	[40]	[36]	-6	hSpCas9	negative selection	10733612
97167494	97167517	5	+	28162770	SKM1	viability	GACGACAAGGCAATTAGATGAGG	RIOK2	ENSG00000058729	-0.4409115306664994	[42]	[55]	-4	hSpCas9	negative selection	10733613
97183125	97183148	5	-	28162770	SKM1	viability	TGACTTCAGGGTCTTGACCGCGG	RIOK2	ENSG00000058729	-3.6799826931495776	[144]	[19]	-9	hSpCas9	negative selection	10733614
97177164	97177187	5	-	28162770	SKM1	viability	AACATAGGCACAATGTGTCATGG	RIOK2	ENSG00000058729	0.6754979614488112	[101]	[287]	6	hSpCas9	negative selection	10733615
97171221	97171244	5	+	28162770	SKM1	viability	TGAGAAGTTGAAACCATCTGTGG	RIOK2	ENSG00000058729	-0.7734215175769439	[145]	[150]	-5	hSpCas9	negative selection	10733616
97167774	97167797	5	-	28162770	PL21	viability	GAACTGTCTAGAAGAATCAGAGG	RIOK2	ENSG00000058729	0.04724071533968077	[357]	[160]	0	hSpCas9	negative selection	10902973
97171196	97171219	5	+	28162770	PL21	viability	AAGTACGTACCACTCAGCATTGG	RIOK2	ENSG00000058729	-1.1096308659718068	[708]	[142]	-6	hSpCas9	negative selection	10902974
97167554	97167577	5	-	28162770	PL21	viability	GATGGTCAGAGAGTTCAAGGAGG	RIOK2	ENSG00000058729	-2.2734016035634133	[410]	[36]	-8	hSpCas9	negative selection	10902975
97179117	97179140	5	-	28162770	PL21	viability	ATAGCCAGCCTTAAACATGGTGG	RIOK2	ENSG00000058729	-3.826660444854395	[162]	[4]	-9	hSpCas9	negative selection	10902976
97177743	97177766	5	-	28162770	PL21	viability	GTTGGAAACCAGATGGGTGTTGG	RIOK2	ENSG00000058729	-1.5003001036517727	[25]	[3]	-7	hSpCas9	negative selection	10902977
97167953	97167976	5	-	28162770	PL21	viability	GATGTGGAGGTTTCTGCCAGTGG	RIOK2	ENSG00000058729	-0.07088758209800428	[180]	[74]	0	hSpCas9	negative selection	10902978
97167494	97167517	5	+	28162770	PL21	viability	GACGACAAGGCAATTAGATGAGG	RIOK2	ENSG00000058729	-0.8665314251559677	[154]	[36]	-5	hSpCas9	negative selection	10902979
97183125	97183148	5	-	28162770	PL21	viability	TGACTTCAGGGTCTTGACCGCGG	RIOK2	ENSG00000058729	-2.86163658309737	[500]	[29]	-9	hSpCas9	negative selection	10902980
97177164	97177187	5	-	28162770	PL21	viability	AACATAGGCACAATGTGTCATGG	RIOK2	ENSG00000058729	0.5585935854017966	[272]	[174]	5	hSpCas9	negative selection	10902981
97171221	97171244	5	+	28162770	PL21	viability	TGAGAAGTTGAAACCATCTGTGG	RIOK2	ENSG00000058729	-0.8066495511733188	[425]	[105]	-5	hSpCas9	negative selection	10902982
97167774	97167797	5	-	28162770	P31FUJ	viability	GAACTGTCTAGAAGAATCAGAGG	RIOK2	ENSG00000058729	-0.853947041442181	[322]	[209]	-6	hSpCas9	negative selection	11072339
97171196	97171219	5	+	28162770	P31FUJ	viability	AAGTACGTACCACTCAGCATTGG	RIOK2	ENSG00000058729	-0.7515475015594708	[840]	[586]	-5	hSpCas9	negative selection	11072340
97167554	97167577	5	-	28162770	P31FUJ	viability	GATGGTCAGAGAGTTCAAGGAGG	RIOK2	ENSG00000058729	-0.805890604847243	[362]	[243]	-6	hSpCas9	negative selection	11072341
97179117	97179140	5	-	28162770	P31FUJ	viability	ATAGCCAGCCTTAAACATGGTGG	RIOK2	ENSG00000058729	-0.7223866570582764	[138]	[98]	-5	hSpCas9	negative selection	11072342
97177743	97177766	5	-	28162770	P31FUJ	viability	GTTGGAAACCAGATGGGTGTTGG	RIOK2	ENSG00000058729	-2.71822903158462	[27]	[4]	-9	hSpCas9	negative selection	11072343
97167953	97167976	5	-	28162770	P31FUJ	viability	GATGTGGAGGTTTCTGCCAGTGG	RIOK2	ENSG00000058729	-1.7275668961639563	[123]	[43]	-8	hSpCas9	negative selection	11072344
97167494	97167517	5	+	28162770	P31FUJ	viability	GACGACAAGGCAATTAGATGAGG	RIOK2	ENSG00000058729	-1.7242780762574255	[238]	[84]	-8	hSpCas9	negative selection	11072345
97183125	97183148	5	-	28162770	P31FUJ	viability	TGACTTCAGGGTCTTGACCGCGG	RIOK2	ENSG00000058729	-3.7705995970568544	[661]	[56]	-9	hSpCas9	negative selection	11072346
97177164	97177187	5	-	28162770	P31FUJ	viability	AACATAGGCACAATGTGTCATGG	RIOK2	ENSG00000058729	0.7358714613917159	[418]	[819]	8	hSpCas9	negative selection	11072347
97171221	97171244	5	+	28162770	P31FUJ	viability	TGAGAAGTTGAAACCATCTGTGG	RIOK2	ENSG00000058729	-2.294517988900794	[596]	[142]	-8	hSpCas9	negative selection	11072348
97167774	97167797	5	-	28162770	OCIAML5	viability	GAACTGTCTAGAAGAATCAGAGG	RIOK2	ENSG00000058729	-1.3528339441687247	[207]	[146]	-7	hSpCas9	negative selection	11241705
97171196	97171219	5	+	28162770	OCIAML5	viability	AAGTACGTACCACTCAGCATTGG	RIOK2	ENSG00000058729	-1.997389599073231	[406]	[183]	-8	hSpCas9	negative selection	11241706
97167554	97167577	5	-	28162770	OCIAML5	viability	GATGGTCAGAGAGTTCAAGGAGG	RIOK2	ENSG00000058729	-1.6550297238044434	[245]	[140]	-7	hSpCas9	negative selection	11241707
97179117	97179140	5	-	28162770	OCIAML5	viability	ATAGCCAGCCTTAAACATGGTGG	RIOK2	ENSG00000058729	-1.6210610192228412	[166]	[97]	-7	hSpCas9	negative selection	11241708
97177743	97177766	5	-	28162770	OCIAML5	viability	GTTGGAAACCAGATGGGTGTTGG	RIOK2	ENSG00000058729	-4.437029071585153	[11]	[0]	-9	hSpCas9	negative selection	11241709
97167953	97167976	5	-	28162770	OCIAML5	viability	GATGTGGAGGTTTCTGCCAGTGG	RIOK2	ENSG00000058729	-1.3259977591964092	[74]	[53]	-6	hSpCas9	negative selection	11241710
97167494	97167517	5	+	28162770	OCIAML5	viability	GACGACAAGGCAATTAGATGAGG	RIOK2	ENSG00000058729	-1.6977384244727032	[123]	[68]	-7	hSpCas9	negative selection	11241711
97183125	97183148	5	-	28162770	OCIAML5	viability	TGACTTCAGGGTCTTGACCGCGG	RIOK2	ENSG00000058729	-4.4287138033731495	[345]	[28]	-9	hSpCas9	negative selection	11241712
97177164	97177187	5	-	28162770	OCIAML5	viability	AACATAGGCACAATGTGTCATGG	RIOK2	ENSG00000058729	0.15853373428974948	[338]	[682]	1	hSpCas9	negative selection	11241713
97171221	97171244	5	+	28162770	OCIAML5	viability	TGAGAAGTTGAAACCATCTGTGG	RIOK2	ENSG00000058729	-1.818707973917566	[341]	[174]	-7	hSpCas9	negative selection	11241714
97167774	97167797	5	-	28162770	EOL1	viability	GAACTGTCTAGAAGAATCAGAGG	RIOK2	ENSG00000058729	-2.2107681929416363	[658]	[74]	-8	hSpCas9	negative selection	11411071
97171196	97171219	5	+	28162770	EOL1	viability	AAGTACGTACCACTCAGCATTGG	RIOK2	ENSG00000058729	-0.7352499620732116	[909]	[287]	-5	hSpCas9	negative selection	11411072
97167554	97167577	5	-	28162770	EOL1	viability	GATGGTCAGAGAGTTCAAGGAGG	RIOK2	ENSG00000058729	-1.7535241335421032	[671]	[104]	-8	hSpCas9	negative selection	11411073
97179117	97179140	5	-	28162770	EOL1	viability	ATAGCCAGCCTTAAACATGGTGG	RIOK2	ENSG00000058729	-1.122757943207822	[309]	[74]	-6	hSpCas9	negative selection	11411074
97177743	97177766	5	-	28162770	EOL1	viability	GTTGGAAACCAGATGGGTGTTGG	RIOK2	ENSG00000058729	-4.630041080107103	[46]	[0]	-9	hSpCas9	negative selection	11411075
97167953	97167976	5	-	28162770	EOL1	viability	GATGTGGAGGTTTCTGCCAGTGG	RIOK2	ENSG00000058729	-2.3207590417139157	[274]	[28]	-8	hSpCas9	negative selection	11411076
97167494	97167517	5	+	28162770	EOL1	viability	GACGACAAGGCAATTAGATGAGG	RIOK2	ENSG00000058729	-2.701891365126781	[246]	[19]	-9	hSpCas9	negative selection	11411077
97183125	97183148	5	-	28162770	EOL1	viability	TGACTTCAGGGTCTTGACCGCGG	RIOK2	ENSG00000058729	-4.014764301730361	[674]	[21]	-9	hSpCas9	negative selection	11411078
97177164	97177187	5	-	28162770	EOL1	viability	AACATAGGCACAATGTGTCATGG	RIOK2	ENSG00000058729	-0.6574246865448101	[481]	[160]	-5	hSpCas9	negative selection	11411079
97171221	97171244	5	+	28162770	EOL1	viability	TGAGAAGTTGAAACCATCTGTGG	RIOK2	ENSG00000058729	-0.14030337277943328	[545]	[260]	-1	hSpCas9	negative selection	11411080
97167774	97167797	5	-	28162770	MOLM13	viability	GAACTGTCTAGAAGAATCAGAGG	RIOK2	ENSG00000058729	-0.46423850556296253	[518]	[271]	-3	hSpCas9	negative selection	11580437
97171196	97171219	5	+	28162770	MOLM13	viability	AAGTACGTACCACTCAGCATTGG	RIOK2	ENSG00000058729	-2.887742017010991	[1125]	[109]	-8	hSpCas9	negative selection	11580438
97167554	97167577	5	-	28162770	MOLM13	viability	GATGGTCAGAGAGTTCAAGGAGG	RIOK2	ENSG00000058729	-1.3424493989518467	[483]	[137]	-6	hSpCas9	negative selection	11580439
97179117	97179140	5	-	28162770	MOLM13	viability	ATAGCCAGCCTTAAACATGGTGG	RIOK2	ENSG00000058729	-1.8946806978401294	[287]	[55]	-7	hSpCas9	negative selection	11580440
97177743	97177766	5	-	28162770	MOLM13	viability	GTTGGAAACCAGATGGGTGTTGG	RIOK2	ENSG00000058729	-4.7415639840843715	[36]	[0]	-9	hSpCas9	negative selection	11580441
97167953	97167976	5	-	28162770	MOLM13	viability	GATGTGGAGGTTTCTGCCAGTGG	RIOK2	ENSG00000058729	-1.473558436100308	[168]	[43]	-6	hSpCas9	negative selection	11580442
97167494	97167517	5	+	28162770	MOLM13	viability	GACGACAAGGCAATTAGATGAGG	RIOK2	ENSG00000058729	-0.1901365813663008	[242]	[153]	-1	hSpCas9	negative selection	11580443
97183125	97183148	5	-	28162770	MOLM13	viability	TGACTTCAGGGTCTTGACCGCGG	RIOK2	ENSG00000058729	-9.005816368074838	[710]	[0]	-9	hSpCas9	negative selection	11580444
97177164	97177187	5	-	28162770	MOLM13	viability	AACATAGGCACAATGTGTCATGG	RIOK2	ENSG00000058729	0.6090392639054979	[466]	[514]	4	hSpCas9	negative selection	11580445
97171221	97171244	5	+	28162770	MOLM13	viability	TGAGAAGTTGAAACCATCTGTGG	RIOK2	ENSG00000058729	-3.0104562084568043	[690]	[61]	-8	hSpCas9	negative selection	11580446
97167774	97167797	5	-	28162770	HEL	viability	GAACTGTCTAGAAGAATCAGAGG	RIOK2	ENSG00000058729	-1.0100957816132579	[543]	[172]	-6	hSpCas9	negative selection	11749803
97171196	97171219	5	+	28162770	HEL	viability	AAGTACGTACCACTCAGCATTGG	RIOK2	ENSG00000058729	-2.210971725748987	[758]	[104]	-8	hSpCas9	negative selection	11749804
97167554	97167577	5	-	28162770	HEL	viability	GATGGTCAGAGAGTTCAAGGAGG	RIOK2	ENSG00000058729	-0.8311923563320553	[449]	[161]	-5	hSpCas9	negative selection	11749805
97179117	97179140	5	-	28162770	HEL	viability	ATAGCCAGCCTTAAACATGGTGG	RIOK2	ENSG00000058729	-3.574491884220312	[278]	[14]	-9	hSpCas9	negative selection	11749806
97177743	97177766	5	-	28162770	HEL	viability	GTTGGAAACCAGATGGGTGTTGG	RIOK2	ENSG00000058729	-4.057700886140735	[25]	[0]	-9	hSpCas9	negative selection	11749807
97167953	97167976	5	-	28162770	HEL	viability	GATGTGGAGGTTTCTGCCAGTGG	RIOK2	ENSG00000058729	-1.620295573833437	[167]	[34]	-7	hSpCas9	negative selection	11749808
97167494	97167517	5	+	28162770	HEL	viability	GACGACAAGGCAATTAGATGAGG	RIOK2	ENSG00000058729	-3.7077584150837763	[203]	[9]	-9	hSpCas9	negative selection	11749809
97183125	97183148	5	-	28162770	HEL	viability	TGACTTCAGGGTCTTGACCGCGG	RIOK2	ENSG00000058729	-1.8741346788786297	[537]	[93]	-7	hSpCas9	negative selection	11749810
97177164	97177187	5	-	28162770	HEL	viability	AACATAGGCACAATGTGTCATGG	RIOK2	ENSG00000058729	0.49073573855530717	[409]	[368]	4	hSpCas9	negative selection	11749811
97171221	97171244	5	+	28162770	HEL	viability	TGAGAAGTTGAAACCATCTGTGG	RIOK2	ENSG00000058729	-3.6821917510485287	[480]	[23]	-9	hSpCas9	negative selection	11749812
97167774	97167797	5	-	28162770	MV411	viability	GAACTGTCTAGAAGAATCAGAGG	RIOK2	ENSG00000058729	-1.140833038933283	[355]	[135]	-6	hSpCas9	negative selection	11919169
97171196	97171219	5	+	28162770	MV411	viability	AAGTACGTACCACTCAGCATTGG	RIOK2	ENSG00000058729	-0.5443464143692855	[598]	[345]	-4	hSpCas9	negative selection	11919170
97167554	97167577	5	-	28162770	MV411	viability	GATGGTCAGAGAGTTCAAGGAGG	RIOK2	ENSG00000058729	-1.1389171937919835	[331]	[126]	-6	hSpCas9	negative selection	11919171
97179117	97179140	5	-	28162770	MV411	viability	ATAGCCAGCCTTAAACATGGTGG	RIOK2	ENSG00000058729	-1.4232548239642648	[155]	[48]	-7	hSpCas9	negative selection	11919172
97177743	97177766	5	-	28162770	MV411	viability	GTTGGAAACCAGATGGGTGTTGG	RIOK2	ENSG00000058729	-4.706758759604099	[30]	[0]	-9	hSpCas9	negative selection	11919173
97167953	97167976	5	-	28162770	MV411	viability	GATGTGGAGGTTTCTGCCAGTGG	RIOK2	ENSG00000058729	-0.6632951111201373	[140]	[74]	-5	hSpCas9	negative selection	11919174
97167494	97167517	5	+	28162770	MV411	viability	GACGACAAGGCAATTAGATGAGG	RIOK2	ENSG00000058729	-1.284576069989422	[106]	[36]	-7	hSpCas9	negative selection	11919175
97183125	97183148	5	-	28162770	MV411	viability	TGACTTCAGGGTCTTGACCGCGG	RIOK2	ENSG00000058729	-4.969087863521676	[408]	[10]	-9	hSpCas9	negative selection	11919176
97177164	97177187	5	-	28162770	MV411	viability	AACATAGGCACAATGTGTCATGG	RIOK2	ENSG00000058729	0.8156243387531047	[345]	[512]	7	hSpCas9	negative selection	11919177
97171221	97171244	5	+	28162770	MV411	viability	TGAGAAGTTGAAACCATCTGTGG	RIOK2	ENSG00000058729	-0.8034633475172627	[374]	[180]	-5	hSpCas9	negative selection	11919178
97167774	97167797	5	-	28162770	MONOMAC1	viability	GAACTGTCTAGAAGAATCAGAGG	RIOK2	ENSG00000058729	-1.2443425618379103	[216]	[104]	-7	hSpCas9	negative selection	12088535
97171196	97171219	5	+	28162770	MONOMAC1	viability	AAGTACGTACCACTCAGCATTGG	RIOK2	ENSG00000058729	-0.8495974259315204	[425]	[270]	-6	hSpCas9	negative selection	12088536
97167554	97167577	5	-	28162770	MONOMAC1	viability	GATGGTCAGAGAGTTCAAGGAGG	RIOK2	ENSG00000058729	-0.5491971433663312	[216]	[169]	-5	hSpCas9	negative selection	12088537
97179117	97179140	5	-	28162770	MONOMAC1	viability	ATAGCCAGCCTTAAACATGGTGG	RIOK2	ENSG00000058729	-1.0616849941646673	[121]	[66]	-7	hSpCas9	negative selection	12088538
97177743	97177766	5	-	28162770	MONOMAC1	viability	GTTGGAAACCAGATGGGTGTTGG	RIOK2	ENSG00000058729	-3.197036847059554	[7]	[0]	-9	hSpCas9	negative selection	12088539
97167953	97167976	5	-	28162770	MONOMAC1	viability	GATGTGGAGGTTTCTGCCAGTGG	RIOK2	ENSG00000058729	-1.8344667676748452	[139]	[44]	-8	hSpCas9	negative selection	12088540
97167494	97167517	5	+	28162770	MONOMAC1	viability	GACGACAAGGCAATTAGATGAGG	RIOK2	ENSG00000058729	-2.8194740531993725	[116]	[18]	-9	hSpCas9	negative selection	12088541
97183125	97183148	5	-	28162770	MONOMAC1	viability	TGACTTCAGGGTCTTGACCGCGG	RIOK2	ENSG00000058729	-3.605842392626883	[307]	[28]	-9	hSpCas9	negative selection	12088542
97177164	97177187	5	-	28162770	MONOMAC1	viability	AACATAGGCACAATGTGTCATGG	RIOK2	ENSG00000058729	0.14026647371472445	[223]	[282]	1	hSpCas9	negative selection	12088543
97171221	97171244	5	+	28162770	MONOMAC1	viability	TGAGAAGTTGAAACCATCTGTGG	RIOK2	ENSG00000058729	-1.4983710072200063	[312]	[126]	-8	hSpCas9	negative selection	12088544
97167774	97167797	5	-	28162770	OCIAML2	viability	GAACTGTCTAGAAGAATCAGAGG	RIOK2	ENSG00000058729	-0.7524007936575408	[61]	[203]	-5	hSpCas9	negative selection	12257901
97171196	97171219	5	+	28162770	OCIAML2	viability	AAGTACGTACCACTCAGCATTGG	RIOK2	ENSG00000058729	-0.8823545904801695	[144]	[435]	-6	hSpCas9	negative selection	12257902
97167554	97167577	5	-	28162770	OCIAML2	viability	GATGGTCAGAGAGTTCAAGGAGG	RIOK2	ENSG00000058729	-1.172949276601476	[71]	[176]	-6	hSpCas9	negative selection	12257903
97179117	97179140	5	-	28162770	OCIAML2	viability	ATAGCCAGCCTTAAACATGGTGG	RIOK2	ENSG00000058729	-1.7601364424371462	[32]	[53]	-8	hSpCas9	negative selection	12257904
97177743	97177766	5	-	28162770	OCIAML2	viability	GTTGGAAACCAGATGGGTGTTGG	RIOK2	ENSG00000058729	-1.470629825242161	[4]	[9]	-7	hSpCas9	negative selection	12257905
97167953	97167976	5	-	28162770	OCIAML2	viability	GATGTGGAGGTTTCTGCCAGTGG	RIOK2	ENSG00000058729	-0.4200037521721932	[20]	[86]	-3	hSpCas9	negative selection	12257906
97167494	97167517	5	+	28162770	OCIAML2	viability	GACGACAAGGCAATTAGATGAGG	RIOK2	ENSG00000058729	-3.310165153048915	[33]	[18]	-9	hSpCas9	negative selection	12257907
97183125	97183148	5	-	28162770	OCIAML2	viability	TGACTTCAGGGTCTTGACCGCGG	RIOK2	ENSG00000058729	-3.979643472730019	[73]	[25]	-9	hSpCas9	negative selection	12257908
97177164	97177187	5	-	28162770	OCIAML2	viability	AACATAGGCACAATGTGTCATGG	RIOK2	ENSG00000058729	0.11433267547899506	[52]	[317]	1	hSpCas9	negative selection	12257909
97171221	97171244	5	+	28162770	OCIAML2	viability	TGAGAAGTTGAAACCATCTGTGG	RIOK2	ENSG00000058729	-1.0555923259633173	[83]	[223]	-6	hSpCas9	negative selection	12257910
97167774	97167797	5	-	28162770	OCIAML3	viability	GAACTGTCTAGAAGAATCAGAGG	RIOK2	ENSG00000058729	-1.0144586357893712	[88]	[132]	-6	hSpCas9	negative selection	12427267
97171196	97171219	5	+	28162770	OCIAML3	viability	AAGTACGTACCACTCAGCATTGG	RIOK2	ENSG00000058729	-0.8809801008147122	[157]	[258]	-6	hSpCas9	negative selection	12427268
97167554	97167577	5	-	28162770	OCIAML3	viability	GATGGTCAGAGAGTTCAAGGAGG	RIOK2	ENSG00000058729	0.03604274992553114	[104]	[324]	0	hSpCas9	negative selection	12427269
97179117	97179140	5	-	28162770	OCIAML3	viability	ATAGCCAGCCTTAAACATGGTGG	RIOK2	ENSG00000058729	-0.3558479031293986	[38]	[91]	-3	hSpCas9	negative selection	12427270
97177743	97177766	5	-	28162770	OCIAML3	viability	GTTGGAAACCAGATGGGTGTTGG	RIOK2	ENSG00000058729	-1.4240826388818504	[7]	[8]	-7	hSpCas9	negative selection	12427271
97167953	97167976	5	-	28162770	OCIAML3	viability	GATGTGGAGGTTTCTGCCAGTGG	RIOK2	ENSG00000058729	-1.0980501456617517	[38]	[54]	-7	hSpCas9	negative selection	12427272
97167494	97167517	5	+	28162770	OCIAML3	viability	GACGACAAGGCAATTAGATGAGG	RIOK2	ENSG00000058729	-2.153435048938182	[55]	[37]	-8	hSpCas9	negative selection	12427273
97183125	97183148	5	-	28162770	OCIAML3	viability	TGACTTCAGGGTCTTGACCGCGG	RIOK2	ENSG00000058729	-2.51048428476188	[150]	[79]	-9	hSpCas9	negative selection	12427274
97177164	97177187	5	-	28162770	OCIAML3	viability	AACATAGGCACAATGTGTCATGG	RIOK2	ENSG00000058729	0.9597361297862728	[108]	[639]	8	hSpCas9	negative selection	12427275
97171221	97171244	5	+	28162770	OCIAML3	viability	TGAGAAGTTGAAACCATCTGTGG	RIOK2	ENSG00000058729	-1.0127207977464052	[130]	[195]	-6	hSpCas9	negative selection	12427276