Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:8767
• Symbol:RIPK2
• Description:receptor interacting serine/threonine kinase 2

DataSource: http://genomecrispr.dkfz.de/#!/results/RIPK2

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
89758051	89758074	8	+	26472758	Jiyoye	viability	GCCCGGGACCATGAACGGGGAGG	RIPK2	ENSG00000104312	0.08524728661851144	[14]	[11]	0	hSpCas9	negative selection	137341
89765399	89765422	8	-	26472758	Jiyoye	viability	GTGCAGGTAATTTACACCAAGGG	RIPK2	ENSG00000104312	-1.3903317545953837	[72]	[20]	-7	hSpCas9	negative selection	137342
89758118	89758141	8	+	26472758	Jiyoye	viability	GACCTGCGCTACCTGAGCCGCGG	RIPK2	ENSG00000104312	0.40717538150587346	[165]	[165]	3	hSpCas9	negative selection	137343
89758074	89758097	8	-	26472758	Jiyoye	viability	GGTGGGCAGGGCGCTGCAGATGG	RIPK2	ENSG00000104312	2.5501333353479163	[11]	[52]	9	hSpCas9	negative selection	137344
89758092	89758115	8	-	26472758	Jiyoye	viability	GAGTTTGTGGTAGGGAATGGTGG	RIPK2	ENSG00000104312	4.407175381505873	[0]	[15]	9	hSpCas9	negative selection	137345
89758165	89758188	8	-	26472758	Jiyoye	viability	GGACGCGCCAGTCTGCGTGGCGG	RIPK2	ENSG00000104312	0.5912073291435614	[146]	[166]	4	hSpCas9	negative selection	137346
89769829	89769852	8	+	26472758	Jiyoye	viability	AGCAAATCTGCACCAGAAGGAGG	RIPK2	ENSG00000104312	0.9867243860406651	[88]	[132]	6	hSpCas9	negative selection	137347
89758143	89758166	8	-	26472758	Jiyoye	viability	GGCGGACGACACAGTGCCAGAGG	RIPK2	ENSG00000104312	-0.12333933519290641	[64]	[44]	-1	hSpCas9	negative selection	137348
89758204	89758227	8	-	26472758	Jiyoye	viability	GCAGCGGAGTGTGGATGTGCAGG	RIPK2	ENSG00000104312	-0.03974617879275644	[243]	[178]	0	hSpCas9	negative selection	137349
89758220	89758243	8	-	26472758	Jiyoye	viability	ACTGCCTACCTGTCGAGCAGCGG	RIPK2	ENSG00000104312	0.9921378822270295	[15]	[23]	6	hSpCas9	negative selection	137350
89758051	89758074	8	+	26472758	KBM7	viability	GCCCGGGACCATGAACGGGGAGG	RIPK2	ENSG00000104312	-0.33187103974039056	[59,55]	[17,24]	-3	hSpCas9	negative selection	328459
89765399	89765422	8	-	26472758	KBM7	viability	GTGCAGGTAATTTACACCAAGGG	RIPK2	ENSG00000104312	-0.16988676811147907	[284,160]	[71,107]	-2	hSpCas9	negative selection	328460
89758118	89758141	8	+	26472758	KBM7	viability	GACCTGCGCTACCTGAGCCGCGG	RIPK2	ENSG00000104312	0.474937724811032	[668,474]	[309,421]	5	hSpCas9	negative selection	328461
89758074	89758097	8	-	26472758	KBM7	viability	GGTGGGCAGGGCGCTGCAGATGG	RIPK2	ENSG00000104312	-0.2496106349910877	[322,179]	[95,97]	-2	hSpCas9	negative selection	328462
89758092	89758115	8	-	26472758	KBM7	viability	GAGTTTGTGGTAGGGAATGGTGG	RIPK2	ENSG00000104312	-0.2666570271488511	[181,56]	[73,17]	-3	hSpCas9	negative selection	328463
89758165	89758188	8	-	26472758	KBM7	viability	GGACGCGCCAGTCTGCGTGGCGG	RIPK2	ENSG00000104312	0.5409952797176831	[564,448]	[344,343]	6	hSpCas9	negative selection	328464
89769829	89769852	8	+	26472758	KBM7	viability	AGCAAATCTGCACCAGAAGGAGG	RIPK2	ENSG00000104312	0.5204663622471097	[514,401]	[290,320]	5	hSpCas9	negative selection	328465
89758143	89758166	8	-	26472758	KBM7	viability	GGCGGACGACACAGTGCCAGAGG	RIPK2	ENSG00000104312	0.2985162116471016	[91,206]	[103,77]	3	hSpCas9	negative selection	328466
89758204	89758227	8	-	26472758	KBM7	viability	GCAGCGGAGTGTGGATGTGCAGG	RIPK2	ENSG00000104312	0.5528594568452677	[973,728]	[693,480]	6	hSpCas9	negative selection	328467
89758220	89758243	8	-	26472758	KBM7	viability	ACTGCCTACCTGTCGAGCAGCGG	RIPK2	ENSG00000104312	-0.1640636077182831	[124,203]	[50,88]	-1	hSpCas9	negative selection	328468
89758051	89758074	8	+	26472758	Raji	viability	GCCCGGGACCATGAACGGGGAGG	RIPK2	ENSG00000104312	0.0629894160151463	[32]	[7]	0	hSpCas9	negative selection	519577
89765399	89765422	8	-	26472758	Raji	viability	GTGCAGGTAATTTACACCAAGGG	RIPK2	ENSG00000104312	0.029381023372326398	[113]	[26]	0	hSpCas9	negative selection	519578
89758118	89758141	8	+	26472758	Raji	viability	GACCTGCGCTACCTGAGCCGCGG	RIPK2	ENSG00000104312	0.9358402555329044	[222]	[98]	8	hSpCas9	negative selection	519579
89758074	89758097	8	-	26472758	Raji	viability	GGTGGGCAGGGCGCTGCAGATGG	RIPK2	ENSG00000104312	1.5053475212935017	[84]	[55]	9	hSpCas9	negative selection	519580
89758092	89758115	8	-	26472758	Raji	viability	GAGTTTGTGGTAGGGAATGGTGG	RIPK2	ENSG00000104312	-0.3374013072992965	[48]	[8]	-3	hSpCas9	negative selection	519581
89758165	89758188	8	-	26472758	Raji	viability	GGACGCGCCAGTCTGCGTGGCGG	RIPK2	ENSG00000104312	0.44441852265117016	[227]	[71]	4	hSpCas9	negative selection	519582
89769829	89769852	8	+	26472758	Raji	viability	AGCAAATCTGCACCAGAAGGAGG	RIPK2	ENSG00000104312	0.31270244335110586	[339]	[97]	3	hSpCas9	negative selection	519583
89758143	89758166	8	-	26472758	Raji	viability	GGCGGACGACACAGTGCCAGAGG	RIPK2	ENSG00000104312	-0.49252930681352836	[96]	[15]	-4	hSpCas9	negative selection	519584
89758204	89758227	8	-	26472758	Raji	viability	GCAGCGGAGTGTGGATGTGCAGG	RIPK2	ENSG00000104312	0.31923921728183025	[372]	[107]	3	hSpCas9	negative selection	519585
89758220	89758243	8	-	26472758	Raji	viability	ACTGCCTACCTGTCGAGCAGCGG	RIPK2	ENSG00000104312	0.6316501044072016	[88]	[31]	6	hSpCas9	negative selection	519586
89758051	89758074	8	+	26472758	K562	viability	GCCCGGGACCATGAACGGGGAGG	RIPK2	ENSG00000104312	-0.7066716718526065	[57]	[29]	-4	hSpCas9	negative selection	710695
89765399	89765422	8	-	26472758	K562	viability	GTGCAGGTAATTTACACCAAGGG	RIPK2	ENSG00000104312	-0.030203652442558848	[149]	[123]	0	hSpCas9	negative selection	710696
89758118	89758141	8	+	26472758	K562	viability	GACCTGCGCTACCTGAGCCGCGG	RIPK2	ENSG00000104312	-0.11867855619731997	[390]	[303]	-1	hSpCas9	negative selection	710697
89758074	89758097	8	-	26472758	K562	viability	GGTGGGCAGGGCGCTGCAGATGG	RIPK2	ENSG00000104312	0.13896942908271714	[226]	[210]	1	hSpCas9	negative selection	710698
89758092	89758115	8	-	26472758	K562	viability	GAGTTTGTGGTAGGGAATGGTGG	RIPK2	ENSG00000104312	1.0238195881530496	[66]	[114]	8	hSpCas9	negative selection	710699
89758165	89758188	8	-	26472758	K562	viability	GGACGCGCCAGTCTGCGTGGCGG	RIPK2	ENSG00000104312	1.1476939562047255	[292]	[547]	8	hSpCas9	negative selection	710700
89769829	89769852	8	+	26472758	K562	viability	AGCAAATCTGCACCAGAAGGAGG	RIPK2	ENSG00000104312	0.06333068114645063	[372]	[328]	0	hSpCas9	negative selection	710701
89758143	89758166	8	-	26472758	K562	viability	GGCGGACGACACAGTGCCAGAGG	RIPK2	ENSG00000104312	0.37934830775255524	[152]	[167]	3	hSpCas9	negative selection	710702
89758204	89758227	8	-	26472758	K562	viability	GCAGCGGAGTGTGGATGTGCAGG	RIPK2	ENSG00000104312	0.24693871964496228	[571]	[572]	2	hSpCas9	negative selection	710703
89758220	89758243	8	-	26472758	K562	viability	ACTGCCTACCTGTCGAGCAGCGG	RIPK2	ENSG00000104312	0.7672595164798055	[86]	[124]	6	hSpCas9	negative selection	710704
89758047	89758070	8	+	26627737	DLD1	viability	GAGCGCCCGGGACCATGAACGGG	RIPK2	ENSG00000104312	-0.38188841814771757	[193]	[30,54,52]	-4	hSpCas9	negative selection	840265
89758095	89758118	8	-	26627737	DLD1	viability	GGCGAGTTTGTGGTAGGGAATGG	RIPK2	ENSG00000104312	-0.00688178358892938	[362]	[208,91,46]	0	hSpCas9	negative selection	840266
89758212	89758235	8	+	26627737	DLD1	viability	TCCACACTCCGCTGCTCGACAGG	RIPK2	ENSG00000104312	0.31742978394018595	[544]	[333,234,87]	3	hSpCas9	negative selection	840267
89789387	89789410	8	-	26627737	DLD1	viability	AGCCCTTTGAGATCCAGAAATGG	RIPK2	ENSG00000104312	0.3842899401780045	[291]	[136,131,92]	4	hSpCas9	negative selection	840268
89789458	89789481	8	-	26627737	DLD1	viability	GAGTTTCCTGCAGTTGAGAGTGG	RIPK2	ENSG00000104312	1.0707307600785787	[154]	[139,110,60]	8	hSpCas9	negative selection	840269
89790179	89790202	8	-	26627737	DLD1	viability	TGATCAAGTCCCTGGACAGAAGG	RIPK2	ENSG00000104312	-0.4455189616323762	[439]	[72,145,87]	-4	hSpCas9	negative selection	840270
89758047	89758070	8	+	26627737	GBM cells	viability after 5 days	GAGCGCCCGGGACCATGAACGGG	RIPK2	ENSG00000104312	-0.5066008502746518	[150]	[39,73]	-7	hSpCas9	negative selection	922580
89758095	89758118	8	-	26627737	GBM cells	viability after 5 days	GGCGAGTTTGTGGTAGGGAATGG	RIPK2	ENSG00000104312	-0.3674408892397197	[260]	[109,106]	-5	hSpCas9	negative selection	922581
89758212	89758235	8	+	26627737	GBM cells	viability after 5 days	TCCACACTCCGCTGCTCGACAGG	RIPK2	ENSG00000104312	-0.10999167833620621	[324]	[145,176]	-2	hSpCas9	negative selection	922582
89789387	89789410	8	-	26627737	GBM cells	viability after 5 days	AGCCCTTTGAGATCCAGAAATGG	RIPK2	ENSG00000104312	0.12937534693112684	[432]	[226,280]	2	hSpCas9	negative selection	922583
89789458	89789481	8	-	26627737	GBM cells	viability after 5 days	GAGTTTCCTGCAGTTGAGAGTGG	RIPK2	ENSG00000104312	0.6373286856889617	[198]	[149,181]	8	hSpCas9	negative selection	922584
89790179	89790202	8	-	26627737	GBM cells	viability after 5 days	TGATCAAGTCCCTGGACAGAAGG	RIPK2	ENSG00000104312	0.2412371905241188	[294]	[194,178]	4	hSpCas9	negative selection	922585
89758047	89758070	8	+	26627737	GBM cells	viability after 13 days	GAGCGCCCGGGACCATGAACGGG	RIPK2	ENSG00000104312	-0.7164821277847825	[150]	[45,52]	-7	hSpCas9	negative selection	1004895
89758095	89758118	8	-	26627737	GBM cells	viability after 13 days	GGCGAGTTTGTGGTAGGGAATGG	RIPK2	ENSG00000104312	-0.16726063858686677	[260]	[140,113]	-2	hSpCas9	negative selection	1004896
89758212	89758235	8	+	26627737	GBM cells	viability after 13 days	TCCACACTCCGCTGCTCGACAGG	RIPK2	ENSG00000104312	-0.1411268512212037	[324]	[176,145]	-2	hSpCas9	negative selection	1004897
89789387	89789410	8	-	26627737	GBM cells	viability after 13 days	AGCCCTTTGAGATCCAGAAATGG	RIPK2	ENSG00000104312	0.19119562855000505	[432]	[313,230]	2	hSpCas9	negative selection	1004898
89789458	89789481	8	-	26627737	GBM cells	viability after 13 days	GAGTTTCCTGCAGTTGAGAGTGG	RIPK2	ENSG00000104312	0.6178314697740486	[198]	[168,162]	7	hSpCas9	negative selection	1004899
89790179	89790202	8	-	26627737	GBM cells	viability after 13 days	TGATCAAGTCCCTGGACAGAAGG	RIPK2	ENSG00000104312	-0.09676438594389697	[294]	[195,111]	-1	hSpCas9	negative selection	1004900
89758047	89758070	8	+	26627737	GBM cells	viability after 21 days	GAGCGCCCGGGACCATGAACGGG	RIPK2	ENSG00000104312	-0.44727891354340577	[150]	[67,52]	-4	hSpCas9	negative selection	1087210
89758095	89758118	8	-	26627737	GBM cells	viability after 21 days	GGCGAGTTTGTGGTAGGGAATGG	RIPK2	ENSG00000104312	0.26124669316166377	[260]	[182,157]	2	hSpCas9	negative selection	1087211
89758212	89758235	8	+	26627737	GBM cells	viability after 21 days	TCCACACTCCGCTGCTCGACAGG	RIPK2	ENSG00000104312	-0.19779661426105374	[324]	[166,141]	-2	hSpCas9	negative selection	1087212
89789387	89789410	8	-	26627737	GBM cells	viability after 21 days	AGCCCTTTGAGATCCAGAAATGG	RIPK2	ENSG00000104312	0.26921500983116253	[432]	[306,261]	3	hSpCas9	negative selection	1087213
89789458	89789481	8	-	26627737	GBM cells	viability after 21 days	GAGTTTCCTGCAGTTGAGAGTGG	RIPK2	ENSG00000104312	0.9789202373647378	[198]	[210,214]	8	hSpCas9	negative selection	1087214
89790179	89790202	8	-	26627737	GBM cells	viability after 21 days	TGATCAAGTCCCTGGACAGAAGG	RIPK2	ENSG00000104312	-0.1302376561493021	[294]	[147,144]	-1	hSpCas9	negative selection	1087215
89758047	89758070	8	+	26627737	RPE1	viability after 9 days	GAGCGCCCGGGACCATGAACGGG	RIPK2	ENSG00000104312	2.1000715099881977	[93]	[85,177]	9	hSpCas9	negative selection	1169525
89758095	89758118	8	-	26627737	RPE1	viability after 9 days	GGCGAGTTTGTGGTAGGGAATGG	RIPK2	ENSG00000104312	-0.15953228587536608	[908]	[211,309]	-1	hSpCas9	negative selection	1169526
89758212	89758235	8	+	26627737	RPE1	viability after 9 days	TCCACACTCCGCTGCTCGACAGG	RIPK2	ENSG00000104312	-0.11439002927950825	[1281]	[96,723]	-1	hSpCas9	negative selection	1169527
89789387	89789410	8	-	26627737	RPE1	viability after 9 days	AGCCCTTTGAGATCCAGAAATGG	RIPK2	ENSG00000104312	-1.1933729568836604	[1862]	[151,387]	-7	hSpCas9	negative selection	1169528
89789458	89789481	8	-	26627737	RPE1	viability after 9 days	GAGTTTCCTGCAGTTGAGAGTGG	RIPK2	ENSG00000104312	0.32079007651525426	[750]	[187,429]	2	hSpCas9	negative selection	1169529
89790179	89790202	8	-	26627737	RPE1	viability after 9 days	TGATCAAGTCCCTGGACAGAAGG	RIPK2	ENSG00000104312	-0.973595146088011	[685]	[104,114]	-6	hSpCas9	negative selection	1169530
89758047	89758070	8	+	26627737	RPE1	viability after 12 days	GAGCGCCCGGGACCATGAACGGG	RIPK2	ENSG00000104312	2.6892388291835956	[93]	[141,184]	9	hSpCas9	negative selection	1251840
89758095	89758118	8	-	26627737	RPE1	viability after 12 days	GGCGAGTTTGTGGTAGGGAATGG	RIPK2	ENSG00000104312	0.3652187589857955	[908]	[333,293]	2	hSpCas9	negative selection	1251841
89758212	89758235	8	+	26627737	RPE1	viability after 12 days	TCCACACTCCGCTGCTCGACAGG	RIPK2	ENSG00000104312	-0.7487901219330452	[1281]	[118,295]	-5	hSpCas9	negative selection	1251842
89789387	89789410	8	-	26627737	RPE1	viability after 12 days	AGCCCTTTGAGATCCAGAAATGG	RIPK2	ENSG00000104312	-1.1279167710182576	[1862]	[178,281]	-6	hSpCas9	negative selection	1251843
89789458	89789481	8	-	26627737	RPE1	viability after 12 days	GAGTTTCCTGCAGTTGAGAGTGG	RIPK2	ENSG00000104312	0.32219362487545056	[750]	[158,350]	2	hSpCas9	negative selection	1251844
89790179	89790202	8	-	26627737	RPE1	viability after 12 days	TGATCAAGTCCCTGGACAGAAGG	RIPK2	ENSG00000104312	0.09588921192262856	[685]	[263,125]	0	hSpCas9	negative selection	1251845
89758047	89758070	8	+	26627737	RPE1	viability after 15 days	GAGCGCCCGGGACCATGAACGGG	RIPK2	ENSG00000104312	2.1670431930566947	[93]	[123,114]	9	hSpCas9	negative selection	1334155
89758095	89758118	8	-	26627737	RPE1	viability after 15 days	GGCGAGTTTGTGGTAGGGAATGG	RIPK2	ENSG00000104312	0.36287910235468723	[908]	[348,312]	2	hSpCas9	negative selection	1334156
89758212	89758235	8	+	26627737	RPE1	viability after 15 days	TCCACACTCCGCTGCTCGACAGG	RIPK2	ENSG00000104312	-0.20746793110949746	[1281]	[112,507]	-1	hSpCas9	negative selection	1334157
89789387	89789410	8	-	26627737	RPE1	viability after 15 days	AGCCCTTTGAGATCCAGAAATGG	RIPK2	ENSG00000104312	-1.250338110021045	[1862]	[191,249]	-7	hSpCas9	negative selection	1334158
89789458	89789481	8	-	26627737	RPE1	viability after 15 days	GAGTTTCCTGCAGTTGAGAGTGG	RIPK2	ENSG00000104312	0.47334108243645634	[750]	[185,399]	3	hSpCas9	negative selection	1334159
89790179	89790202	8	-	26627737	RPE1	viability after 15 days	TGATCAAGTCCCTGGACAGAAGG	RIPK2	ENSG00000104312	-0.20584349782445804	[685]	[125,208]	-1	hSpCas9	negative selection	1334160
89758047	89758070	8	+	26627737	RPE1	viability after 18 days	GAGCGCCCGGGACCATGAACGGG	RIPK2	ENSG00000104312	2.495381007995438	[93]	[85,203]	9	hSpCas9	negative selection	1416470
89758095	89758118	8	-	26627737	RPE1	viability after 18 days	GGCGAGTTTGTGGTAGGGAATGG	RIPK2	ENSG00000104312	0.14231773614626492	[908]	[306,231]	0	hSpCas9	negative selection	1416471
89758212	89758235	8	+	26627737	RPE1	viability after 18 days	TCCACACTCCGCTGCTCGACAGG	RIPK2	ENSG00000104312	-0.27811164385589815	[1281]	[104,477]	-2	hSpCas9	negative selection	1416472
89789387	89789410	8	-	26627737	RPE1	viability after 18 days	AGCCCTTTGAGATCCAGAAATGG	RIPK2	ENSG00000104312	-1.131080566325581	[1862]	[230,227]	-6	hSpCas9	negative selection	1416473
89789458	89789481	8	-	26627737	RPE1	viability after 18 days	GAGTTTCCTGCAGTTGAGAGTGG	RIPK2	ENSG00000104312	0.509343719244463	[750]	[185,397]	3	hSpCas9	negative selection	1416474
89790179	89790202	8	-	26627737	RPE1	viability after 18 days	TGATCAAGTCCCTGGACAGAAGG	RIPK2	ENSG00000104312	-0.8253318382761448	[685]	[132,73]	-5	hSpCas9	negative selection	1416475
89758047	89758070	8	+	26627737	HeLa	viability after 8 days	GAGCGCCCGGGACCATGAACGGG	RIPK2	ENSG00000104312	-0.4684830420317869	[418]	[135,124,134]	-4	hSpCas9	negative selection	1498785
89758095	89758118	8	-	26627737	HeLa	viability after 8 days	GGCGAGTTTGTGGTAGGGAATGG	RIPK2	ENSG00000104312	0.13484282756542715	[499]	[355,244,147]	1	hSpCas9	negative selection	1498786
89758212	89758235	8	+	26627737	HeLa	viability after 8 days	TCCACACTCCGCTGCTCGACAGG	RIPK2	ENSG00000104312	-0.39165473605170525	[640]	[258,249,143]	-4	hSpCas9	negative selection	1498787
89789387	89789410	8	-	26627737	HeLa	viability after 8 days	AGCCCTTTGAGATCCAGAAATGG	RIPK2	ENSG00000104312	0.5512664437721525	[389]	[216,316,207]	5	hSpCas9	negative selection	1498788
89789458	89789481	8	-	26627737	HeLa	viability after 8 days	GAGTTTCCTGCAGTTGAGAGTGG	RIPK2	ENSG00000104312	1.0832552525091417	[213]	[266,168,172]	8	hSpCas9	negative selection	1498789
89790179	89790202	8	-	26627737	HeLa	viability after 8 days	TGATCAAGTCCCTGGACAGAAGG	RIPK2	ENSG00000104312	0.0316188916108715	[579]	[326,172,286]	0	hSpCas9	negative selection	1498790
89758047	89758070	8	+	26627737	HeLa	viability after 12 days	GAGCGCCCGGGACCATGAACGGG	RIPK2	ENSG00000104312	-0.3595427786994924	[418]	[36,106,260]	-3	hSpCas9	negative selection	1581100
89758095	89758118	8	-	26627737	HeLa	viability after 12 days	GGCGAGTTTGTGGTAGGGAATGG	RIPK2	ENSG00000104312	0.2377949028011636	[499]	[231,277,216]	2	hSpCas9	negative selection	1581101
89758212	89758235	8	+	26627737	HeLa	viability after 12 days	TCCACACTCCGCTGCTCGACAGG	RIPK2	ENSG00000104312	-0.5808425172357277	[640]	[143,255,121]	-5	hSpCas9	negative selection	1581102
89789387	89789410	8	-	26627737	HeLa	viability after 12 days	AGCCCTTTGAGATCCAGAAATGG	RIPK2	ENSG00000104312	0.7114795586299548	[389]	[339,206,252]	6	hSpCas9	negative selection	1581103
89789458	89789481	8	-	26627737	HeLa	viability after 12 days	GAGTTTCCTGCAGTTGAGAGTGG	RIPK2	ENSG00000104312	1.1333634460511086	[213]	[204,234,137]	7	hSpCas9	negative selection	1581104
89790179	89790202	8	-	26627737	HeLa	viability after 12 days	TGATCAAGTCCCTGGACAGAAGG	RIPK2	ENSG00000104312	-0.802627018212319	[579]	[123,154,130]	-6	hSpCas9	negative selection	1581105
89758047	89758070	8	+	26627737	HeLa	viability after 15 days	GAGCGCCCGGGACCATGAACGGG	RIPK2	ENSG00000104312	0.04750296863336055	[418]	[283,96,143]	0	hSpCas9	negative selection	1663415
89758095	89758118	8	-	26627737	HeLa	viability after 15 days	GGCGAGTTTGTGGTAGGGAATGG	RIPK2	ENSG00000104312	0.21104743552363897	[499]	[63,373,273]	1	hSpCas9	negative selection	1663416
89758212	89758235	8	+	26627737	HeLa	viability after 15 days	TCCACACTCCGCTGCTCGACAGG	RIPK2	ENSG00000104312	-0.8312245841817962	[640]	[161,152,122]	-6	hSpCas9	negative selection	1663417
89789387	89789410	8	-	26627737	HeLa	viability after 15 days	AGCCCTTTGAGATCCAGAAATGG	RIPK2	ENSG00000104312	0.8210433071675652	[389]	[310,286,239]	6	hSpCas9	negative selection	1663418
89789458	89789481	8	-	26627737	HeLa	viability after 15 days	GAGTTTCCTGCAGTTGAGAGTGG	RIPK2	ENSG00000104312	0.8691634586944408	[213]	[152,146,178]	6	hSpCas9	negative selection	1663419
89790179	89790202	8	-	26627737	HeLa	viability after 15 days	TGATCAAGTCCCTGGACAGAAGG	RIPK2	ENSG00000104312	-0.535753822107444	[579]	[217,105,163]	-5	hSpCas9	negative selection	1663420
89758047	89758070	8	+	26627737	HeLa	viability after 18 days	GAGCGCCCGGGACCATGAACGGG	RIPK2	ENSG00000104312	0.06419473343282851	[418]	[193,80,143]	0	hSpCas9	negative selection	1745730
89758095	89758118	8	-	26627737	HeLa	viability after 18 days	GGCGAGTTTGTGGTAGGGAATGG	RIPK2	ENSG00000104312	0.21956188954880312	[499]	[42,312,273]	1	hSpCas9	negative selection	1745731
89758212	89758235	8	+	26627737	HeLa	viability after 18 days	TCCACACTCCGCTGCTCGACAGG	RIPK2	ENSG00000104312	-0.8213826353277845	[640]	[111,124,122]	-6	hSpCas9	negative selection	1745732
89789387	89789410	8	-	26627737	HeLa	viability after 18 days	AGCCCTTTGAGATCCAGAAATGG	RIPK2	ENSG00000104312	0.7933170175229394	[389]	[193,242,239]	6	hSpCas9	negative selection	1745733
89789458	89789481	8	-	26627737	HeLa	viability after 18 days	GAGTTTCCTGCAGTTGAGAGTGG	RIPK2	ENSG00000104312	0.876444477403762	[213]	[103,121,178]	6	hSpCas9	negative selection	1745734
89790179	89790202	8	-	26627737	HeLa	viability after 18 days	TGATCAAGTCCCTGGACAGAAGG	RIPK2	ENSG00000104312	-0.5135554697558394	[579]	[146,92,163]	-4	hSpCas9	negative selection	1745735
89758047	89758070	8	+	26627737	HCT116	viability after 6 days	GAGCGCCCGGGACCATGAACGGG	RIPK2	ENSG00000104312	-1.4216746068145132	[486]	[25,29]	-7	hSpCas9	negative selection	1828045
89758095	89758118	8	-	26627737	HCT116	viability after 6 days	GGCGAGTTTGTGGTAGGGAATGG	RIPK2	ENSG00000104312	0.22626772165211034	[426]	[122,53]	1	hSpCas9	negative selection	1828046
89758212	89758235	8	+	26627737	HCT116	viability after 6 days	TCCACACTCCGCTGCTCGACAGG	RIPK2	ENSG00000104312	1.6394979193795078	[398]	[304,134]	8	hSpCas9	negative selection	1828047
89789387	89789410	8	-	26627737	HCT116	viability after 6 days	AGCCCTTTGAGATCCAGAAATGG	RIPK2	ENSG00000104312	-0.1900480907326184	[964]	[112,143]	-1	hSpCas9	negative selection	1828048
89789458	89789481	8	-	26627737	HCT116	viability after 6 days	GAGTTTCCTGCAGTTGAGAGTGG	RIPK2	ENSG00000104312	0.857050146658308	[516]	[36,207]	5	hSpCas9	negative selection	1828049
89790179	89790202	8	-	26627737	HCT116	viability after 6 days	TGATCAAGTCCCTGGACAGAAGG	RIPK2	ENSG00000104312	0.43449553647382233	[680]	[47,197]	2	hSpCas9	negative selection	1828050
89758047	89758070	8	+	26627737	HCT116	viability after 8 days	GAGCGCCCGGGACCATGAACGGG	RIPK2	ENSG00000104312	0.6737710879044104	[105]	[79,81,116]	6	hSpCas9	negative selection	1910360
89758095	89758118	8	-	26627737	HCT116	viability after 8 days	GGCGAGTTTGTGGTAGGGAATGG	RIPK2	ENSG00000104312	0.5923197916063416	[261]	[209,237,204]	6	hSpCas9	negative selection	1910361
89758212	89758235	8	+	26627737	HCT116	viability after 8 days	TCCACACTCCGCTGCTCGACAGG	RIPK2	ENSG00000104312	1.0241935978974563	[162]	[183,177,185]	8	hSpCas9	negative selection	1910362
89789387	89789410	8	-	26627737	HCT116	viability after 8 days	AGCCCTTTGAGATCCAGAAATGG	RIPK2	ENSG00000104312	0.20848526084249758	[365]	[267,221,209]	2	hSpCas9	negative selection	1910363
89789458	89789481	8	-	26627737	HCT116	viability after 8 days	GAGTTTCCTGCAGTTGAGAGTGG	RIPK2	ENSG00000104312	0.17249996555229055	[285]	[181,180,169]	2	hSpCas9	negative selection	1910364
89790179	89790202	8	-	26627737	HCT116	viability after 8 days	TGATCAAGTCCCTGGACAGAAGG	RIPK2	ENSG00000104312	1.194336238272167	[182]	[233,282,175]	8	hSpCas9	negative selection	1910365
89758047	89758070	8	+	26627737	HCT116	viability after 9 days	GAGCGCCCGGGACCATGAACGGG	RIPK2	ENSG00000104312	0.15792743984236027	[486]	[129,156]	1	hSpCas9	negative selection	1992675
89758095	89758118	8	-	26627737	HCT116	viability after 9 days	GGCGAGTTTGTGGTAGGGAATGG	RIPK2	ENSG00000104312	1.0933137627525498	[426]	[130,331]	7	hSpCas9	negative selection	1992676
89758212	89758235	8	+	26627737	HCT116	viability after 9 days	TCCACACTCCGCTGCTCGACAGG	RIPK2	ENSG00000104312	0.6786395852596554	[398]	[112,215]	5	hSpCas9	negative selection	1992677
89789387	89789410	8	-	26627737	HCT116	viability after 9 days	AGCCCTTTGAGATCCAGAAATGG	RIPK2	ENSG00000104312	-1.2583640054739857	[964]	[119,97]	-7	hSpCas9	negative selection	1992678
89789458	89789481	8	-	26627737	HCT116	viability after 9 days	GAGTTTCCTGCAGTTGAGAGTGG	RIPK2	ENSG00000104312	1.4398433069797771	[516]	[340,400]	8	hSpCas9	negative selection	1992679
89790179	89790202	8	-	26627737	HCT116	viability after 9 days	TGATCAAGTCCCTGGACAGAAGG	RIPK2	ENSG00000104312	0.5714973680487576	[680]	[248,286]	4	hSpCas9	negative selection	1992680
89758047	89758070	8	+	26627737	HCT116	viability after 12 days	GAGCGCCCGGGACCATGAACGGG	RIPK2	ENSG00000104312	0.6511757216213356	[105]	[62,103,97]	6	hSpCas9	negative selection	2074990
89758095	89758118	8	-	26627737	HCT116	viability after 12 days	GGCGAGTTTGTGGTAGGGAATGG	RIPK2	ENSG00000104312	0.6686587327996432	[261]	[184,194,278]	6	hSpCas9	negative selection	2074991
89758212	89758235	8	+	26627737	HCT116	viability after 12 days	TCCACACTCCGCTGCTCGACAGG	RIPK2	ENSG00000104312	1.239526533262241	[162]	[199,243,163]	8	hSpCas9	negative selection	2074992
89789387	89789410	8	-	26627737	HCT116	viability after 12 days	AGCCCTTTGAGATCCAGAAATGG	RIPK2	ENSG00000104312	-0.05226638334401121	[365]	[215,192,144]	0	hSpCas9	negative selection	2074993
89789458	89789481	8	-	26627737	HCT116	viability after 12 days	GAGTTTCCTGCAGTTGAGAGTGG	RIPK2	ENSG00000104312	0.1877425801894878	[285]	[141,206,167]	2	hSpCas9	negative selection	2074994
89790179	89790202	8	-	26627737	HCT116	viability after 12 days	TGATCAAGTCCCTGGACAGAAGG	RIPK2	ENSG00000104312	0.9195347633108436	[182]	[215,192,133]	7	hSpCas9	negative selection	2074995
89758047	89758070	8	+	26627737	HCT116	viability after 15 days	GAGCGCCCGGGACCATGAACGGG	RIPK2	ENSG00000104312	0.7797389887200465	[105]	[118,66,128]	6	hSpCas9	negative selection	2157305
89758095	89758118	8	-	26627737	HCT116	viability after 15 days	GGCGAGTTTGTGGTAGGGAATGG	RIPK2	ENSG00000104312	0.30390938526493205	[261]	[140,158,250]	3	hSpCas9	negative selection	2157306
89758212	89758235	8	+	26627737	HCT116	viability after 15 days	TCCACACTCCGCTGCTCGACAGG	RIPK2	ENSG00000104312	0.5724209756597736	[162]	[201,146,76]	5	hSpCas9	negative selection	2157307
89789387	89789410	8	-	26627737	HCT116	viability after 15 days	AGCCCTTTGAGATCCAGAAATGG	RIPK2	ENSG00000104312	0.29839286250889574	[365]	[435,179,181]	3	hSpCas9	negative selection	2157308
89789458	89789481	8	-	26627737	HCT116	viability after 15 days	GAGTTTCCTGCAGTTGAGAGTGG	RIPK2	ENSG00000104312	0.3827754589120913	[285]	[198,175,264]	4	hSpCas9	negative selection	2157309
89790179	89790202	8	-	26627737	HCT116	viability after 15 days	TGATCAAGTCCCTGGACAGAAGG	RIPK2	ENSG00000104312	0.7211916119974205	[182]	[242,173,111]	6	hSpCas9	negative selection	2157310
89758047	89758070	8	+	26627737	HCT116	viability after 18 days	GAGCGCCCGGGACCATGAACGGG	RIPK2	ENSG00000104312	0.2073387925433854	[105]	[53,56,66]	1	hSpCas9	negative selection	2239620
89758095	89758118	8	-	26627737	HCT116	viability after 18 days	GGCGAGTTTGTGGTAGGGAATGG	RIPK2	ENSG00000104312	0.41156825140332076	[261]	[85,188,231]	3	hSpCas9	negative selection	2239621
89758212	89758235	8	+	26627737	HCT116	viability after 18 days	TCCACACTCCGCTGCTCGACAGG	RIPK2	ENSG00000104312	0.7283962434447493	[162]	[208,146,29]	6	hSpCas9	negative selection	2239622
89789387	89789410	8	-	26627737	HCT116	viability after 18 days	AGCCCTTTGAGATCCAGAAATGG	RIPK2	ENSG00000104312	-0.3958676940479593	[365]	[190,97,115]	-4	hSpCas9	negative selection	2239623
89789458	89789481	8	-	26627737	HCT116	viability after 18 days	GAGTTTCCTGCAGTTGAGAGTGG	RIPK2	ENSG00000104312	-0.3419995042402032	[285]	[89,101,136]	-3	hSpCas9	negative selection	2239624
89790179	89790202	8	-	26627737	HCT116	viability after 18 days	TGATCAAGTCCCTGGACAGAAGG	RIPK2	ENSG00000104312	0.7344967411728265	[182]	[185,144,108]	6	hSpCas9	negative selection	2239625
89758046	89758069	8	+	24336569	HL60	viability	TGAGCGCCCGGGACCATGAACGG	RIPK2	ENSG00000104312	0.2465900970553075	[657]	[1651]	2	hSpCas9	negative selection	2289715
89758074	89758097	8	-	24336569	HL60	viability	GGTGGGCAGGGCGCTGCAGATGG	RIPK2	ENSG00000104312	-0.0023354508443569344	[1010]	[2135]	0	hSpCas9	negative selection	2289716
89758086	89758109	8	-	24336569	HL60	viability	GTGGTAGGGAATGGTGGGCAGGG	RIPK2	ENSG00000104312	1.5319534251807518	[660]	[4044]	9	hSpCas9	negative selection	2289717
89758091	89758114	8	-	24336569	HL60	viability	AGTTTGTGGTAGGGAATGGTGGG	RIPK2	ENSG00000104312	0.09408632726900279	[710]	[1605]	0	hSpCas9	negative selection	2289718
89758100	89758123	8	-	24336569	HL60	viability	AGGTCGGCGAGTTTGTGGTAGGG	RIPK2	ENSG00000104312	0.992117031752211	[515]	[2171]	7	hSpCas9	negative selection	2289719
89758105	89758128	8	-	24336569	HL60	viability	AGCGCAGGTCGGCGAGTTTGTGG	RIPK2	ENSG00000104312	-0.3499432872275454	[1698]	[2820]	-3	hSpCas9	negative selection	2289720
89758116	89758139	8	-	24336569	HL60	viability	GCGGCTCAGGTAGCGCAGGTCGG	RIPK2	ENSG00000104312	-0.5892818848633494	[486]	[684]	-5	hSpCas9	negative selection	2289721
89758127	89758150	8	+	24336569	HL60	viability	TACCTGAGCCGCGGCGCCTCTGG	RIPK2	ENSG00000104312	1.2184616826568422	[184]	[910]	8	hSpCas9	negative selection	2289722
89758135	89758158	8	-	24336569	HL60	viability	ACACAGTGCCAGAGGCGCCGCGG	RIPK2	ENSG00000104312	-0.3506336707312857	[1083]	[1798]	-3	hSpCas9	negative selection	2289723
89758143	89758166	8	-	24336569	HL60	viability	GGCGGACGACACAGTGCCAGAGG	RIPK2	ENSG00000104312	0.5269505630450835	[1138]	[3472]	5	hSpCas9	negative selection	2289724
89758046	89758069	8	+	24336569	KBM7	viability	TGAGCGCCCGGGACCATGAACGG	RIPK2	ENSG00000104312	0.48986886603560575	[435]	[1669]	4	hSpCas9	negative selection	2356892
89758074	89758097	8	-	24336569	KBM7	viability	GGTGGGCAGGGCGCTGCAGATGG	RIPK2	ENSG00000104312	0.052023399385726865	[556]	[1574]	0	hSpCas9	negative selection	2356893
89758086	89758109	8	-	24336569	KBM7	viability	GTGGTAGGGAATGGTGGGCAGGG	RIPK2	ENSG00000104312	-0.6921595083052463	[1304]	[2202]	-5	hSpCas9	negative selection	2356894
89758091	89758114	8	-	24336569	KBM7	viability	AGTTTGTGGTAGGGAATGGTGGG	RIPK2	ENSG00000104312	-0.2421100782489032	[489]	[1129]	-2	hSpCas9	negative selection	2356895
89758100	89758123	8	-	24336569	KBM7	viability	AGGTCGGCGAGTTTGTGGTAGGG	RIPK2	ENSG00000104312	-0.4520205393306573	[487]	[972]	-4	hSpCas9	negative selection	2356896
89758105	89758128	8	-	24336569	KBM7	viability	AGCGCAGGTCGGCGAGTTTGTGG	RIPK2	ENSG00000104312	0.13654379583267606	[1145]	[3435]	1	hSpCas9	negative selection	2356897
89758116	89758139	8	-	24336569	KBM7	viability	GCGGCTCAGGTAGCGCAGGTCGG	RIPK2	ENSG00000104312	-0.8549689192770229	[438]	[661]	-6	hSpCas9	negative selection	2356898
89758127	89758150	8	+	24336569	KBM7	viability	TACCTGAGCCGCGGCGCCTCTGG	RIPK2	ENSG00000104312	0.17350272997892566	[354]	[1091]	1	hSpCas9	negative selection	2356899
89758135	89758158	8	-	24336569	KBM7	viability	ACACAGTGCCAGAGGCGCCGCGG	RIPK2	ENSG00000104312	0.2647243433830547	[707]	[2319]	2	hSpCas9	negative selection	2356900
89758143	89758166	8	-	24336569	KBM7	viability	GGCGGACGACACAGTGCCAGAGG	RIPK2	ENSG00000104312	-0.625421649435131	[1495]	[2644]	-5	hSpCas9	negative selection	2356901
89762087	89762110	8	-	25494202	A375	resistance to PLX-4720 (puromycin)	TTCAAGCCATCCTCCCACCTTAG	RIPK2	ENSG00000104312	-1.0550787617713646	[224,291]	[11,42]	-6	dCas9-VP64	positive selection	2436395
89773985	89774008	8	+	25494202	A375	resistance to PLX-4720 (puromycin)	CAGGAGGATCACTTGAGCCCAGG	RIPK2	ENSG00000104312	1.3448043646809227	[134,24]	[56,28]	5	dCas9-VP64	positive selection	2469827
89762087	89762110	8	-	25494202	A375	resistance to PLX-4720 (zeocin)	TTCAAGCCATCCTCCCACCTTAG	RIPK2	ENSG00000104312	0.12096276410502044	[78,167]	[40,44]	1	dCas9-VP64	positive selection	2531650
89773985	89774008	8	+	25494202	A375	resistance to PLX-4720 (zeocin)	CAGGAGGATCACTTGAGCCCAGG	RIPK2	ENSG00000104312	0.9689409693551694	[107,845]	[92,495]	6	dCas9-VP64	positive selection	2565082
89765385	89765408	8	-	27260157	DLD1	viability	CACCAAGGGCAATTTCATGCAGG	RIPK2	ENSG00000104312	-0.475247808897087	[]	[]	-4	hSpCas9	negative selection	2573602
89758074	89758097	8	-	27260157	DLD1	viability	GGTGGGCAGGGCGCTGCAGATGG	RIPK2	ENSG00000104312	-1.86678041035672	[]	[]	-8	hSpCas9	negative selection	2575285
89758135	89758158	8	-	27260157	DLD1	viability	ACACAGTGCCAGAGGCGCCGCGG	RIPK2	ENSG00000104312	0.0892984523483867	[]	[]	3	hSpCas9	negative selection	2576605
89758143	89758166	8	-	27260157	DLD1	viability	GGCGGACGACACAGTGCCAGAGG	RIPK2	ENSG00000104312	-0.352450388753169	[]	[]	-3	hSpCas9	negative selection	2579134
89758164	89758187	8	-	27260157	DLD1	viability	GACGCGCCAGTCTGCGTGGCGGG	RIPK2	ENSG00000104312	0.145420868323829	[]	[]	3	hSpCas9	negative selection	2582614
89765353	89765376	8	-	27260157	DLD1	viability	CTCAATGGCCAAGCAACATCAGG	RIPK2	ENSG00000104312	0.684062299662523	[]	[]	8	hSpCas9	negative selection	2585932
89758040	89758063	8	-	27260157	DLD1	viability	ATGGTCCCGGGCGCTCAGGCCGG	RIPK2	ENSG00000104312	-0.182957082657601	[]	[]	-1	hSpCas9	negative selection	2606851
89758086	89758109	8	-	27260157	DLD1	viability	GTGGTAGGGAATGGTGGGCAGGG	RIPK2	ENSG00000104312	-0.706940792638187	[]	[]	-5	hSpCas9	negative selection	2612858
89758220	89758243	8	-	27260157	DLD1	viability	ACTGCCTACCTGTCGAGCAGCGG	RIPK2	ENSG00000104312	-0.302461824881686	[]	[]	-2	hSpCas9	negative selection	2613183
89758105	89758128	8	-	27260157	DLD1	viability	AGCGCAGGTCGGCGAGTTTGTGG	RIPK2	ENSG00000104312	-1.25995455834374	[]	[]	-7	hSpCas9	negative selection	2616005
89758091	89758114	8	-	27260157	DLD1	viability	AGTTTGTGGTAGGGAATGGTGGG	RIPK2	ENSG00000104312	-0.336843141374634	[]	[]	-3	hSpCas9	negative selection	2617213
89765368	89765391	8	-	27260157	DLD1	viability	TGCAGGATGCGAAATCTCAATGG	RIPK2	ENSG00000104312	0.392597502587164	[]	[]	4	hSpCas9	negative selection	2617415
89758100	89758123	8	-	27260157	DLD1	viability	AGGTCGGCGAGTTTGTGGTAGGG	RIPK2	ENSG00000104312	-1.00888383603489	[]	[]	-7	hSpCas9	negative selection	2622061
89758186	89758209	8	-	27260157	DLD1	viability	GCAGGTGCTTCACGGCCACCTGG	RIPK2	ENSG00000104312	-0.578756594029056	[]	[]	-5	hSpCas9	negative selection	2641172
89758116	89758139	8	-	27260157	DLD1	viability	GCGGCTCAGGTAGCGCAGGTCGG	RIPK2	ENSG00000104312	-0.0559728075889468	[]	[]	0	hSpCas9	negative selection	2642751
89758168	89758191	8	+	27260157	DLD1	viability	CCACGCAGACTGGCGCGTCCAGG	RIPK2	ENSG00000104312	-0.429021439082861	[]	[]	-4	hSpCas9	negative selection	2643849
89765383	89765406	8	+	27260157	DLD1	viability	ATCCTGCATGAAATTGCCCTTGG	RIPK2	ENSG00000104312	0.867928894951939	[]	[]	9	hSpCas9	negative selection	2646551
89758046	89758069	8	+	27260157	DLD1	viability	TGAGCGCCCGGGACCATGAACGG	RIPK2	ENSG00000104312	0.803042189909367	[]	[]	9	hSpCas9	negative selection	2646712
89758204	89758227	8	-	27260157	DLD1	viability	GCAGCGGAGTGTGGATGTGCAGG	RIPK2	ENSG00000104312	-1.00011381260194	[]	[]	-7	hSpCas9	negative selection	2646808
89758127	89758150	8	+	27260157	DLD1	viability	TACCTGAGCCGCGGCGCCTCTGG	RIPK2	ENSG00000104312	-0.12609953040149	[]	[]	-1	hSpCas9	negative selection	2647963
89765385	89765408	8	-	27260157	HT1080	viability	CACCAAGGGCAATTTCATGCAGG	RIPK2	ENSG00000104312	0.16673697380718	[]	[]	1	hSpCas9	negative selection	2649732
89758074	89758097	8	-	27260157	HT1080	viability	GGTGGGCAGGGCGCTGCAGATGG	RIPK2	ENSG00000104312	-0.0739695133484312	[]	[]	0	hSpCas9	negative selection	2651415
89758135	89758158	8	-	27260157	HT1080	viability	ACACAGTGCCAGAGGCGCCGCGG	RIPK2	ENSG00000104312	-0.315437748303201	[]	[]	-7	hSpCas9	negative selection	2652735
89758143	89758166	8	-	27260157	HT1080	viability	GGCGGACGACACAGTGCCAGAGG	RIPK2	ENSG00000104312	1.01651572073927	[]	[]	8	hSpCas9	negative selection	2655264
89758164	89758187	8	-	27260157	HT1080	viability	GACGCGCCAGTCTGCGTGGCGGG	RIPK2	ENSG00000104312	-0.145162225687188	[]	[]	0	hSpCas9	negative selection	2658744
89765353	89765376	8	-	27260157	HT1080	viability	CTCAATGGCCAAGCAACATCAGG	RIPK2	ENSG00000104312	1.77874623018851	[]	[]	9	hSpCas9	negative selection	2662062
89758040	89758063	8	-	27260157	HT1080	viability	ATGGTCCCGGGCGCTCAGGCCGG	RIPK2	ENSG00000104312	0.742266527375895	[]	[]	6	hSpCas9	negative selection	2682981
89758086	89758109	8	-	27260157	HT1080	viability	GTGGTAGGGAATGGTGGGCAGGG	RIPK2	ENSG00000104312	-0.408557039002552	[]	[]	-7	hSpCas9	negative selection	2688988
89758220	89758243	8	-	27260157	HT1080	viability	ACTGCCTACCTGTCGAGCAGCGG	RIPK2	ENSG00000104312	0.192035293893354	[]	[]	1	hSpCas9	negative selection	2689313
89758105	89758128	8	-	27260157	HT1080	viability	AGCGCAGGTCGGCGAGTTTGTGG	RIPK2	ENSG00000104312	0.0720711767167668	[]	[]	0	hSpCas9	negative selection	2692135
89758091	89758114	8	-	27260157	HT1080	viability	AGTTTGTGGTAGGGAATGGTGGG	RIPK2	ENSG00000104312	-0.350447571498645	[]	[]	-7	hSpCas9	negative selection	2693343
89765368	89765391	8	-	27260157	HT1080	viability	TGCAGGATGCGAAATCTCAATGG	RIPK2	ENSG00000104312	0.403502224000269	[]	[]	3	hSpCas9	negative selection	2693545
89758100	89758123	8	-	27260157	HT1080	viability	AGGTCGGCGAGTTTGTGGTAGGG	RIPK2	ENSG00000104312	0.36828090231551	[]	[]	3	hSpCas9	negative selection	2698191
89758186	89758209	8	-	27260157	HT1080	viability	GCAGGTGCTTCACGGCCACCTGG	RIPK2	ENSG00000104312	1.18469596856946	[]	[]	8	hSpCas9	negative selection	2717302
89758116	89758139	8	-	27260157	HT1080	viability	GCGGCTCAGGTAGCGCAGGTCGG	RIPK2	ENSG00000104312	-0.413932849440641	[]	[]	-7	hSpCas9	negative selection	2718881
89758168	89758191	8	+	27260157	HT1080	viability	CCACGCAGACTGGCGCGTCCAGG	RIPK2	ENSG00000104312	-0.640931323058942	[]	[]	-8	hSpCas9	negative selection	2719979
89765383	89765406	8	+	27260157	HT1080	viability	ATCCTGCATGAAATTGCCCTTGG	RIPK2	ENSG00000104312	1.61158819307093	[]	[]	9	hSpCas9	negative selection	2722681
89758046	89758069	8	+	27260157	HT1080	viability	TGAGCGCCCGGGACCATGAACGG	RIPK2	ENSG00000104312	0.791268200217018	[]	[]	7	hSpCas9	negative selection	2722842
89758204	89758227	8	-	27260157	HT1080	viability	GCAGCGGAGTGTGGATGTGCAGG	RIPK2	ENSG00000104312	0.165991990400226	[]	[]	1	hSpCas9	negative selection	2722938
89758127	89758150	8	+	27260157	HT1080	viability	TACCTGAGCCGCGGCGCCTCTGG	RIPK2	ENSG00000104312	0.235532488948592	[]	[]	2	hSpCas9	negative selection	2724093
89765385	89765408	8	-	27260157	MKN45	viability	CACCAAGGGCAATTTCATGCAGG	RIPK2	ENSG00000104312	-0.162018970106025	[]	[]	0	hSpCas9	negative selection	2725862
89758074	89758097	8	-	27260157	MKN45	viability	GGTGGGCAGGGCGCTGCAGATGG	RIPK2	ENSG00000104312	-1.84511424748867	[]	[]	-9	hSpCas9	negative selection	2727545
89758135	89758158	8	-	27260157	MKN45	viability	ACACAGTGCCAGAGGCGCCGCGG	RIPK2	ENSG00000104312	-0.554670582743219	[]	[]	-6	hSpCas9	negative selection	2728865
89758143	89758166	8	-	27260157	MKN45	viability	GGCGGACGACACAGTGCCAGAGG	RIPK2	ENSG00000104312	-0.598524522811452	[]	[]	-6	hSpCas9	negative selection	2731394
89758164	89758187	8	-	27260157	MKN45	viability	GACGCGCCAGTCTGCGTGGCGGG	RIPK2	ENSG00000104312	1.20773213657392	[]	[]	9	hSpCas9	negative selection	2734874
89765353	89765376	8	-	27260157	MKN45	viability	CTCAATGGCCAAGCAACATCAGG	RIPK2	ENSG00000104312	1.91386361970068	[]	[]	9	hSpCas9	negative selection	2738192
89758040	89758063	8	-	27260157	MKN45	viability	ATGGTCCCGGGCGCTCAGGCCGG	RIPK2	ENSG00000104312	0.6485855394824	[]	[]	7	hSpCas9	negative selection	2759111
89758086	89758109	8	-	27260157	MKN45	viability	GTGGTAGGGAATGGTGGGCAGGG	RIPK2	ENSG00000104312	-1.12331814195321	[]	[]	-8	hSpCas9	negative selection	2765118
89758220	89758243	8	-	27260157	MKN45	viability	ACTGCCTACCTGTCGAGCAGCGG	RIPK2	ENSG00000104312	0.178457476330088	[]	[]	5	hSpCas9	negative selection	2765443
89758105	89758128	8	-	27260157	MKN45	viability	AGCGCAGGTCGGCGAGTTTGTGG	RIPK2	ENSG00000104312	-0.313632774337752	[]	[]	-1	hSpCas9	negative selection	2768265
89758091	89758114	8	-	27260157	MKN45	viability	AGTTTGTGGTAGGGAATGGTGGG	RIPK2	ENSG00000104312	-0.918503013674472	[]	[]	-7	hSpCas9	negative selection	2769473
89765368	89765391	8	-	27260157	MKN45	viability	TGCAGGATGCGAAATCTCAATGG	RIPK2	ENSG00000104312	-0.857622169512469	[]	[]	-7	hSpCas9	negative selection	2769675
89758100	89758123	8	-	27260157	MKN45	viability	AGGTCGGCGAGTTTGTGGTAGGG	RIPK2	ENSG00000104312	-0.656394322782246	[]	[]	-7	hSpCas9	negative selection	2774321
89758186	89758209	8	-	27260157	MKN45	viability	GCAGGTGCTTCACGGCCACCTGG	RIPK2	ENSG00000104312	0.0394778415718983	[]	[]	0	hSpCas9	negative selection	2793432
89758116	89758139	8	-	27260157	MKN45	viability	GCGGCTCAGGTAGCGCAGGTCGG	RIPK2	ENSG00000104312	-0.185645156873454	[]	[]	0	hSpCas9	negative selection	2795011
89758168	89758191	8	+	27260157	MKN45	viability	CCACGCAGACTGGCGCGTCCAGG	RIPK2	ENSG00000104312	0.720224630106947	[]	[]	7	hSpCas9	negative selection	2796109
89765383	89765406	8	+	27260157	MKN45	viability	ATCCTGCATGAAATTGCCCTTGG	RIPK2	ENSG00000104312	1.36117018252825	[]	[]	9	hSpCas9	negative selection	2798811
89758046	89758069	8	+	27260157	MKN45	viability	TGAGCGCCCGGGACCATGAACGG	RIPK2	ENSG00000104312	1.18276002690637	[]	[]	8	hSpCas9	negative selection	2798972
89758204	89758227	8	-	27260157	MKN45	viability	GCAGCGGAGTGTGGATGTGCAGG	RIPK2	ENSG00000104312	0.944408928603227	[]	[]	8	hSpCas9	negative selection	2799068
89758127	89758150	8	+	27260157	MKN45	viability	TACCTGAGCCGCGGCGCCTCTGG	RIPK2	ENSG00000104312	0.857695568543073	[]	[]	8	hSpCas9	negative selection	2800223
89765385	89765408	8	-	27260157	RKO	viability	CACCAAGGGCAATTTCATGCAGG	RIPK2	ENSG00000104312	-1.47024892365706	[]	[]	-8	hSpCas9	negative selection	2801992
89758074	89758097	8	-	27260157	RKO	viability	GGTGGGCAGGGCGCTGCAGATGG	RIPK2	ENSG00000104312	-1.58444291294738	[]	[]	-9	hSpCas9	negative selection	2803675
89758135	89758158	8	-	27260157	RKO	viability	ACACAGTGCCAGAGGCGCCGCGG	RIPK2	ENSG00000104312	-1.10725706317294	[]	[]	-8	hSpCas9	negative selection	2804995
89758143	89758166	8	-	27260157	RKO	viability	GGCGGACGACACAGTGCCAGAGG	RIPK2	ENSG00000104312	-0.876246707578857	[]	[]	-8	hSpCas9	negative selection	2807524
89758164	89758187	8	-	27260157	RKO	viability	GACGCGCCAGTCTGCGTGGCGGG	RIPK2	ENSG00000104312	0.452697831847578	[]	[]	2	hSpCas9	negative selection	2811004
89765353	89765376	8	-	27260157	RKO	viability	CTCAATGGCCAAGCAACATCAGG	RIPK2	ENSG00000104312	1.25055920183525	[]	[]	9	hSpCas9	negative selection	2814322
89758040	89758063	8	-	27260157	RKO	viability	ATGGTCCCGGGCGCTCAGGCCGG	RIPK2	ENSG00000104312	-0.719600549822784	[]	[]	-7	hSpCas9	negative selection	2835241
89758086	89758109	8	-	27260157	RKO	viability	GTGGTAGGGAATGGTGGGCAGGG	RIPK2	ENSG00000104312	-1.5078771190906	[]	[]	-8	hSpCas9	negative selection	2841248
89758220	89758243	8	-	27260157	RKO	viability	ACTGCCTACCTGTCGAGCAGCGG	RIPK2	ENSG00000104312	-0.444487615611659	[]	[]	-6	hSpCas9	negative selection	2841573
89758105	89758128	8	-	27260157	RKO	viability	AGCGCAGGTCGGCGAGTTTGTGG	RIPK2	ENSG00000104312	-0.805425885277444	[]	[]	-7	hSpCas9	negative selection	2844395
89758091	89758114	8	-	27260157	RKO	viability	AGTTTGTGGTAGGGAATGGTGGG	RIPK2	ENSG00000104312	-1.88513686068399	[]	[]	-9	hSpCas9	negative selection	2845603
89765368	89765391	8	-	27260157	RKO	viability	TGCAGGATGCGAAATCTCAATGG	RIPK2	ENSG00000104312	-0.754942460127935	[]	[]	-7	hSpCas9	negative selection	2845805
89758100	89758123	8	-	27260157	RKO	viability	AGGTCGGCGAGTTTGTGGTAGGG	RIPK2	ENSG00000104312	-0.862991866263386	[]	[]	-8	hSpCas9	negative selection	2850451
89758186	89758209	8	-	27260157	RKO	viability	GCAGGTGCTTCACGGCCACCTGG	RIPK2	ENSG00000104312	0.208229846298006	[]	[]	1	hSpCas9	negative selection	2869562
89758116	89758139	8	-	27260157	RKO	viability	GCGGCTCAGGTAGCGCAGGTCGG	RIPK2	ENSG00000104312	-2.21502455867888	[]	[]	-9	hSpCas9	negative selection	2871141
89758168	89758191	8	+	27260157	RKO	viability	CCACGCAGACTGGCGCGTCCAGG	RIPK2	ENSG00000104312	-0.0396096337122504	[]	[]	0	hSpCas9	negative selection	2872239
89765383	89765406	8	+	27260157	RKO	viability	ATCCTGCATGAAATTGCCCTTGG	RIPK2	ENSG00000104312	0.133908578273672	[]	[]	0	hSpCas9	negative selection	2874941
89758046	89758069	8	+	27260157	RKO	viability	TGAGCGCCCGGGACCATGAACGG	RIPK2	ENSG00000104312	0.0688726866934227	[]	[]	0	hSpCas9	negative selection	2875102
89758204	89758227	8	-	27260157	RKO	viability	GCAGCGGAGTGTGGATGTGCAGG	RIPK2	ENSG00000104312	0.0440990188211574	[]	[]	0	hSpCas9	negative selection	2875198
89758127	89758150	8	+	27260157	RKO	viability	TACCTGAGCCGCGGCGCCTCTGG	RIPK2	ENSG00000104312	-0.577140487754333	[]	[]	-7	hSpCas9	negative selection	2876353
89765385	89765408	8	-	27260157	SF268	viability	CACCAAGGGCAATTTCATGCAGG	RIPK2	ENSG00000104312	-0.501801405434306	[]	[]	-4	hSpCas9	negative selection	2878122
89758074	89758097	8	-	27260157	SF268	viability	GGTGGGCAGGGCGCTGCAGATGG	RIPK2	ENSG00000104312	-0.235861060568892	[]	[]	-2	hSpCas9	negative selection	2879805
89758135	89758158	8	-	27260157	SF268	viability	ACACAGTGCCAGAGGCGCCGCGG	RIPK2	ENSG00000104312	0.0317438707779226	[]	[]	0	hSpCas9	negative selection	2881125
89758143	89758166	8	-	27260157	SF268	viability	GGCGGACGACACAGTGCCAGAGG	RIPK2	ENSG00000104312	0.112794560223547	[]	[]	0	hSpCas9	negative selection	2883654
89758164	89758187	8	-	27260157	SF268	viability	GACGCGCCAGTCTGCGTGGCGGG	RIPK2	ENSG00000104312	0.241269446652155	[]	[]	3	hSpCas9	negative selection	2887134
89765353	89765376	8	-	27260157	SF268	viability	CTCAATGGCCAAGCAACATCAGG	RIPK2	ENSG00000104312	1.10748623104594	[]	[]	9	hSpCas9	negative selection	2890452
89758040	89758063	8	-	27260157	SF268	viability	ATGGTCCCGGGCGCTCAGGCCGG	RIPK2	ENSG00000104312	0.212177444967104	[]	[]	3	hSpCas9	negative selection	2911371
89758086	89758109	8	-	27260157	SF268	viability	GTGGTAGGGAATGGTGGGCAGGG	RIPK2	ENSG00000104312	-0.503895927096586	[]	[]	-4	hSpCas9	negative selection	2917378
89758220	89758243	8	-	27260157	SF268	viability	ACTGCCTACCTGTCGAGCAGCGG	RIPK2	ENSG00000104312	-0.156278463850442	[]	[]	-1	hSpCas9	negative selection	2917703
89758105	89758128	8	-	27260157	SF268	viability	AGCGCAGGTCGGCGAGTTTGTGG	RIPK2	ENSG00000104312	0.347759998123675	[]	[]	4	hSpCas9	negative selection	2920525
89758091	89758114	8	-	27260157	SF268	viability	AGTTTGTGGTAGGGAATGGTGGG	RIPK2	ENSG00000104312	0.0077111913686111	[]	[]	0	hSpCas9	negative selection	2921733
89765368	89765391	8	-	27260157	SF268	viability	TGCAGGATGCGAAATCTCAATGG	RIPK2	ENSG00000104312	0.212548224610862	[]	[]	3	hSpCas9	negative selection	2921935
89758100	89758123	8	-	27260157	SF268	viability	AGGTCGGCGAGTTTGTGGTAGGG	RIPK2	ENSG00000104312	-1.03960145063743	[]	[]	-7	hSpCas9	negative selection	2926581
89758186	89758209	8	-	27260157	SF268	viability	GCAGGTGCTTCACGGCCACCTGG	RIPK2	ENSG00000104312	0.0142819439449362	[]	[]	0	hSpCas9	negative selection	2945692
89758116	89758139	8	-	27260157	SF268	viability	GCGGCTCAGGTAGCGCAGGTCGG	RIPK2	ENSG00000104312	-0.592791653105902	[]	[]	-4	hSpCas9	negative selection	2947271
89758168	89758191	8	+	27260157	SF268	viability	CCACGCAGACTGGCGCGTCCAGG	RIPK2	ENSG00000104312	0.660468304138177	[]	[]	8	hSpCas9	negative selection	2948369
89765383	89765406	8	+	27260157	SF268	viability	ATCCTGCATGAAATTGCCCTTGG	RIPK2	ENSG00000104312	1.17059881751504	[]	[]	9	hSpCas9	negative selection	2951071
89758046	89758069	8	+	27260157	SF268	viability	TGAGCGCCCGGGACCATGAACGG	RIPK2	ENSG00000104312	1.40323744922345	[]	[]	9	hSpCas9	negative selection	2951232
89758204	89758227	8	-	27260157	SF268	viability	GCAGCGGAGTGTGGATGTGCAGG	RIPK2	ENSG00000104312	1.16422850892109	[]	[]	9	hSpCas9	negative selection	2951328
89758127	89758150	8	+	27260157	SF268	viability	TACCTGAGCCGCGGCGCCTCTGG	RIPK2	ENSG00000104312	0.518406409272734	[]	[]	8	hSpCas9	negative selection	2952483
89758135	89758158	8	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	ACACAGTGCCAGAGGCGCCGCGG	RIPK2	ENSG00000104312	0.4688013773208644	[2,2]	[1,4]	8	hSpCas9	positive selection	3016944
89758119	89758142	8	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GACCTGCGCTACCTGAGCCGCGG	RIPK2	ENSG00000104312	0.39468190684906235	[3,2]	[1,4]	7	hSpCas9	positive selection	3016945
89769809	89769832	8	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCTACTTCGTGACTGTGAGAGGG	RIPK2	ENSG00000104312	-0.2845293233559144	[4,4]	[4,2]	-4	hSpCas9	positive selection	3016946
89765399	89765422	8	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GTGCAGGTAATTTACACCAAGGG	RIPK2	ENSG00000104312	-0.032495059899382395	[4,4]	[3,3]	0	hSpCas9	positive selection	3016947
89758135	89758158	8	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	ACACAGTGCCAGAGGCGCCGCGG	RIPK2	ENSG00000104312	-0.4858565120573453	[2,2]	[1,0]	-7	hSpCas9	positive selection	3084802
89758119	89758142	8	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GACCTGCGCTACCTGAGCCGCGG	RIPK2	ENSG00000104312	0.1469374518086356	[3,3]	[1,2]	2	hSpCas9	positive selection	3084803
89769809	89769832	8	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCTACTTCGTGACTGTGAGAGGG	RIPK2	ENSG00000104312	0.15324069492054748	[4,4]	[4,2]	2	hSpCas9	positive selection	3084804
89765399	89765422	8	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GTGCAGGTAATTTACACCAAGGG	RIPK2	ENSG00000104312	0.20280766752300608	[4,4]	[5,1]	3	hSpCas9	positive selection	3084805
89769905	89769928		-	24336571	A375	resistance to PLX after 7 days	ATATATATCGTGCTTGATACTGG	RIPK2	ENSG00000104312	0.03503024870603627	[9,10]	[11,9]	1	hSpCas9	positive selection	3141047
89765400	89765423		-	24336571	A375	resistance to PLX after 7 days	TGTGCAGGTAATTTACACCAAGG	RIPK2	ENSG00000104312	-0.11638743173011687	[10,12]	[11,9]	-4	hSpCas9	positive selection	3141048
89769905	89769928		-	24336571	A375	resistance to PLX after 14 days	ATATATATCGTGCTTGATACTGG	RIPK2	ENSG00000104312	0.3495558954684467	[12,10]	[5,7]	3	hSpCas9	positive selection	3198840
89765400	89765423		-	24336571	A375	resistance to PLX after 14 days	TGTGCAGGTAATTTACACCAAGG	RIPK2	ENSG00000104312	-0.8416108330672669	[13,13]	[3,2]	-8	hSpCas9	positive selection	3198841
89769905	89769928		-	24336571	A375	viability after 7 days	ATATATATCGTGCTTGATACTGG	RIPK2	ENSG00000104312	-0.38931579270386724	[14]	[9,10]	-5	hSpCas9	negative selection	3256633
89765400	89765423		-	24336571	A375	viability after 7 days	TGTGCAGGTAATTTACACCAAGG	RIPK2	ENSG00000104312	0.005815316998813741	[11]	[10,12]	0	hSpCas9	negative selection	3256634
89769905	89769928		-	24336571	A375	viability after 14 days	ATATATATCGTGCTTGATACTGG	RIPK2	ENSG00000104312	-0.20562632319682606	[14]	[12,10]	-2	hSpCas9	negative selection	3314426
89765400	89765423		-	24336571	A375	viability after 14 days	TGTGCAGGTAATTTACACCAAGG	RIPK2	ENSG00000104312	0.26558414085016113	[11]	[13,13]	3	hSpCas9	negative selection	3314427
89765400	89765423	8	-	27383988	293T	resistance to West Nile virus (flavivirus)	TGTGCAGGTAATTTACACCAAGG	RIPK2	ENSG00000104312	-0.8248228299080366	[270,270]	[0,0]	-5	hSpCas9	positive selection	3389918
89771737	89771760	8	+	27383988	293T	resistance to West Nile virus (flavivirus)	ACAGCTATGCAGTTATCACATGG	RIPK2	ENSG00000104312	-0.4291743157373832	[205,205]	[0,0]	-3	hSpCas9	positive selection	3389919
89769868	89769891	8	+	27383988	293T	resistance to West Nile virus (flavivirus)	CCACCTGAAAACTATGAACCTGG	RIPK2	ENSG00000104312	0.057653866609470694	[146,146]	[0,0]	0	hSpCas9	positive selection	3389920
89758135	89758158	8	-	26780180	HT29	viability (Avana library 4 designs)	ACACAGTGCCAGAGGCGCCGCGG	RIPK2	ENSG00000104312	0.967012002901507	[]	[]	4	hSpCas9	negative selection	3455309
89758118	89758141	8	+	26780180	HT29	viability (Avana library 4 designs)	GACCTGCGCTACCTGAGCCGCGG	RIPK2	ENSG00000104312	1.28670412587537	[]	[]	5	hSpCas9	negative selection	3455310
89769809	89769832	8	-	26780180	HT29	viability (Avana library 4 designs)	GCTACTTCGTGACTGTGAGAGGG	RIPK2	ENSG00000104312	0.630221520845473	[]	[]	2	hSpCas9	negative selection	3455311
89765399	89765422	8	-	26780180	HT29	viability (Avana library 4 designs)	GTGCAGGTAATTTACACCAAGGG	RIPK2	ENSG00000104312	0.344983797273312	[]	[]	1	hSpCas9	negative selection	3455312
89758135	89758158	8	-	26780180	A375	viability (Avana lentiCRISPRv2)	ACACAGTGCCAGAGGCGCCGCGG	RIPK2	ENSG00000104312	3.22373113095822	[]	[]	5	hSpCas9	negative selection	3553240
89758118	89758141	8	+	26780180	A375	viability (Avana lentiCRISPRv2)	GACCTGCGCTACCTGAGCCGCGG	RIPK2	ENSG00000104312	3.5603063433267	[]	[]	5	hSpCas9	negative selection	3553241
89769809	89769832	8	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCTACTTCGTGACTGTGAGAGGG	RIPK2	ENSG00000104312	3.25333675597112	[]	[]	5	hSpCas9	negative selection	3553242
89765399	89765422	8	-	26780180	A375	viability (Avana lentiCRISPRv2)	GTGCAGGTAATTTACACCAAGGG	RIPK2	ENSG00000104312	1.89867749983042	[]	[]	2	hSpCas9	negative selection	3553243
89769830	89769853	8	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCAAATCTGCACCAGAAGGAGGG	RIPK2	ENSG00000104312	0.521422120286888	[]	[]	0	hSpCas9	negative selection	3553244
89769908	89769931	8	+	26780180	A375	viability (Avana lentiCRISPRv2)	GTATCAAGCACGATATATATAGG	RIPK2	ENSG00000104312	-11.1626199538259	[]	[]	-8	hSpCas9	negative selection	3553245
89758135	89758158	8	-	26780180	A375	viability (Avana lentiGuide)	ACACAGTGCCAGAGGCGCCGCGG	RIPK2	ENSG00000104312	-2.08268603787041	[]	[]	-4	hSpCas9	negative selection	3661899
89758118	89758141	8	+	26780180	A375	viability (Avana lentiGuide)	GACCTGCGCTACCTGAGCCGCGG	RIPK2	ENSG00000104312	0.424848354810928	[]	[]	0	hSpCas9	negative selection	3661900
89769809	89769832	8	-	26780180	A375	viability (Avana lentiGuide)	GCTACTTCGTGACTGTGAGAGGG	RIPK2	ENSG00000104312	0.87424776515438	[]	[]	1	hSpCas9	negative selection	3661901
89765399	89765422	8	-	26780180	A375	viability (Avana lentiGuide)	GTGCAGGTAATTTACACCAAGGG	RIPK2	ENSG00000104312	-2.44021895062397	[]	[]	-4	hSpCas9	negative selection	3661902
89769830	89769853	8	+	26780180	A375	viability (Avana lentiGuide)	GCAAATCTGCACCAGAAGGAGGG	RIPK2	ENSG00000104312	3.44611875616712	[]	[]	3	hSpCas9	negative selection	3661903
89769908	89769931	8	+	26780180	A375	viability (Avana lentiGuide)	GTATCAAGCACGATATATATAGG	RIPK2	ENSG00000104312	0.774565458114091	[]	[]	0	hSpCas9	negative selection	3661904
89758135	89758158	8	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ACACAGTGCCAGAGGCGCCGCGG	RIPK2	ENSG00000104312	0.07953257015225647	[4]	[5,3]	2	hSpCas9	positive selection	3770506
89758118	89758141	8	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GACCTGCGCTACCTGAGCCGCGG	RIPK2	ENSG00000104312	0.011901446640966207	[4]	[5,3]	0	hSpCas9	positive selection	3770507
89769809	89769832	8	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCTACTTCGTGACTGTGAGAGGG	RIPK2	ENSG00000104312	0.011193936791638853	[5]	[6,5]	0	hSpCas9	positive selection	3770508
89765399	89765422	8	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GTGCAGGTAATTTACACCAAGGG	RIPK2	ENSG00000104312	0.0864161480697995	[6]	[6,6]	2	hSpCas9	positive selection	3770509
89769830	89769853	8	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCAAATCTGCACCAGAAGGAGGG	RIPK2	ENSG00000104312	0.1930668896415064	[4]	[3,5]	5	hSpCas9	positive selection	3770510
89769908	89769931	8	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GTATCAAGCACGATATATATAGG	RIPK2	ENSG00000104312	-0.7368951111440241	[8]	[3,4]	-8	hSpCas9	positive selection	3770511
89758135	89758158	8	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ACACAGTGCCAGAGGCGCCGCGG	RIPK2	ENSG00000104312	-0.009575681684422216	[4]	[3,3]	0	hSpCas9	positive selection	3879113
89758118	89758141	8	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GACCTGCGCTACCTGAGCCGCGG	RIPK2	ENSG00000104312	-0.5824077357748909	[4]	[1,3]	-6	hSpCas9	positive selection	3879114
89769809	89769832	8	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCTACTTCGTGACTGTGAGAGGG	RIPK2	ENSG00000104312	0.11570789729605943	[6]	[6,5]	2	hSpCas9	positive selection	3879115
89765399	89765422	8	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GTGCAGGTAATTTACACCAAGGG	RIPK2	ENSG00000104312	0.2313711458974055	[5]	[5,5]	6	hSpCas9	positive selection	3879116
89769830	89769853	8	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCAAATCTGCACCAGAAGGAGGG	RIPK2	ENSG00000104312	0.14814975612824405	[4]	[5,3]	3	hSpCas9	positive selection	3879117
89769908	89769931	8	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GTATCAAGCACGATATATATAGG	RIPK2	ENSG00000104312	0.22820371897723712	[5]	[6,5]	6	hSpCas9	positive selection	3879118
89771737	89771760	8	+	26780180	A375	viability	ACAGCTATGCAGTTATCACATGG	RIPK2	ENSG00000104312	1.05700598057802	[]	[]	5	hSpCas9	negative selection	3989217
89769905	89769928	8	-	26780180	A375	viability	ATATATATCGTGCTTGATACTGG	RIPK2	ENSG00000104312	2.10851585657814	[]	[]	9	hSpCas9	negative selection	3989218
89769868	89769891	8	+	26780180	A375	viability	CCACCTGAAAACTATGAACCTGG	RIPK2	ENSG00000104312	1.79715958506317	[]	[]	9	hSpCas9	negative selection	3989219
89769908	89769931	8	+	26780180	A375	viability	GTATCAAGCACGATATATATAGG	RIPK2	ENSG00000104312	0.974757942401939	[]	[]	4	hSpCas9	negative selection	3989220
89765368	89765391	8	-	26780180	A375	viability	TGCAGGATGCGAAATCTCAATGG	RIPK2	ENSG00000104312	0.091352947064114	[]	[]	0	hSpCas9	negative selection	3989221
89765400	89765423	8	-	26780180	A375	viability	TGTGCAGGTAATTTACACCAAGG	RIPK2	ENSG00000104312	1.11544893708699	[]	[]	5	hSpCas9	negative selection	3989222
89771737	89771760	8	+	26780180	HT29	viability (GeCKOv2 library)	ACAGCTATGCAGTTATCACATGG	RIPK2	ENSG00000104312	0.985535901065953	[]	[]	4	hSpCas9	negative selection	4097183
89769905	89769928	8	-	26780180	HT29	viability (GeCKOv2 library)	ATATATATCGTGCTTGATACTGG	RIPK2	ENSG00000104312	2.37327509196091	[]	[]	9	hSpCas9	negative selection	4097184
89769868	89769891	8	+	26780180	HT29	viability (GeCKOv2 library)	CCACCTGAAAACTATGAACCTGG	RIPK2	ENSG00000104312	2.16593980528738	[]	[]	9	hSpCas9	negative selection	4097185
89769908	89769931	8	+	26780180	HT29	viability (GeCKOv2 library)	GTATCAAGCACGATATATATAGG	RIPK2	ENSG00000104312	0.939745013883193	[]	[]	4	hSpCas9	negative selection	4097186
89765368	89765391	8	-	26780180	HT29	viability (GeCKOv2 library)	TGCAGGATGCGAAATCTCAATGG	RIPK2	ENSG00000104312	-0.224604051935664	[]	[]	-6	hSpCas9	negative selection	4097187
89765400	89765423	8	-	26780180	HT29	viability (GeCKOv2 library)	TGTGCAGGTAATTTACACCAAGG	RIPK2	ENSG00000104312	1.14473813732147	[]	[]	5	hSpCas9	negative selection	4097188
89769905	89769928	8	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	ATATATATCGTGCTTGATACTGG	RIPK2	ENSG00000104312	0.2144955256421846	[2]	[1,2]	5	hSpCas9	positive selection	4166543
89765400	89765423	8	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TGTGCAGGTAATTTACACCAAGG	RIPK2	ENSG00000104312	-0.06886422033205492	[3]	[2,1]	-2	hSpCas9	positive selection	4166544
89769905	89769928	8	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	ATATATATCGTGCTTGATACTGG	RIPK2	ENSG00000104312	0.7208495564210003	[4]	[1,2,1,3]	4	hSpCas9	positive selection	4230565
89765400	89765423	8	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TGTGCAGGTAATTTACACCAAGG	RIPK2	ENSG00000104312	0.6672913100999037	[3]	[0,0,1,3]	4	hSpCas9	positive selection	4230566
89769905	89769928	8	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ATATATATCGTGCTTGATACTGG	RIPK2	ENSG00000104312	-0.4110983219080398	[3]	[3,0]	-7	hSpCas9	positive selection	4294950
89765368	89765391	8	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TGCAGGATGCGAAATCTCAATGG	RIPK2	ENSG00000104312	0.21093893822356513	[0]	[0,0]	4	hSpCas9	positive selection	4294951
89769908	89769931	8	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GTATCAAGCACGATATATATAGG	RIPK2	ENSG00000104312	0.1981010757975426	[3]	[3,2]	4	hSpCas9	positive selection	4294952
89765400	89765423	8	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TGTGCAGGTAATTTACACCAAGG	RIPK2	ENSG00000104312	0.09628954838665116	[3]	[3,2]	2	hSpCas9	positive selection	4359204
89771737	89771760	8	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ACAGCTATGCAGTTATCACATGG	RIPK2	ENSG00000104312	-0.043679221121073135	[3]	[3,1]	-1	hSpCas9	positive selection	4359205
89769868	89769891	8	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCACCTGAAAACTATGAACCTGG	RIPK2	ENSG00000104312	-0.518632429911076	[2]	[1,0]	-8	hSpCas9	positive selection	4359206
89758165	89758187	8	-	27760321	OCIAML3	viability	GACGCGCCAGTCTGCGTGGCGG	RIPK2	ENSG00000104312	-0.16323679433996807	[987,860]	[529,792]	-2	hSpCas9	negative selection	4434775
89765353	89765375	8	-	27760321	OCIAML3	viability	TCAATGGCCAAGCAACATCAGG	RIPK2	ENSG00000104312	-0.4451851092781469	[309,224]	[116,197]	-4	hSpCas9	negative selection	4434776
89769810	89769832	8	-	27760321	OCIAML3	viability	GCTACTTCGTGACTGTGAGAGG	RIPK2	ENSG00000104312	0.6671059934610513	[602,509]	[616,781]	7	hSpCas9	negative selection	4434777
89772678	89772700	8	-	27760321	OCIAML3	viability	CACTATACATTATCTGCAAAGG	RIPK2	ENSG00000104312	-1.8149498365091583	[45,48]	[17,0]	-9	hSpCas9	negative selection	4434778
89772753	89772775	8	-	27760321	OCIAML3	viability	AGATCATACGTGCTCGGTGAGG	RIPK2	ENSG00000104312	0.6578967599394415	[517,560]	[696,634]	7	hSpCas9	negative selection	4434779
89758165	89758187	8	-	27760321	OCIAML2	viability	GACGCGCCAGTCTGCGTGGCGG	RIPK2	ENSG00000104312	0.007647875647110558	[987,860]	[611,931]	0	hSpCas9	negative selection	4518238
89765353	89765375	8	-	27760321	OCIAML2	viability	TCAATGGCCAAGCAACATCAGG	RIPK2	ENSG00000104312	0.12305154395044327	[309,224]	[200,275]	1	hSpCas9	negative selection	4518239
89769810	89769832	8	-	27760321	OCIAML2	viability	GCTACTTCGTGACTGTGAGAGG	RIPK2	ENSG00000104312	0.1536676382394176	[602,509]	[457,552]	2	hSpCas9	negative selection	4518240
89772678	89772700	8	-	27760321	OCIAML2	viability	CACTATACATTATCTGCAAAGG	RIPK2	ENSG00000104312	0.1695949442369633	[45,48]	[36,51]	2	hSpCas9	negative selection	4518241
89772753	89772775	8	-	27760321	OCIAML2	viability	AGATCATACGTGCTCGGTGAGG	RIPK2	ENSG00000104312	0.15790456955905063	[517,560]	[411,592]	2	hSpCas9	negative selection	4518242
89758165	89758187	8	-	27760321	MV411	viability	GACGCGCCAGTCTGCGTGGCGG	RIPK2	ENSG00000104312	0.7506499014245913	[987,860]	[868,1256]	5	hSpCas9	negative selection	4601701
89765353	89765375	8	-	27760321	MV411	viability	TCAATGGCCAAGCAACATCAGG	RIPK2	ENSG00000104312	0.7223724749993339	[309,224]	[50,644]	5	hSpCas9	negative selection	4601702
89769810	89769832	8	-	27760321	MV411	viability	GCTACTTCGTGACTGTGAGAGG	RIPK2	ENSG00000104312	1.553029368732141	[602,509]	[994,1191]	9	hSpCas9	negative selection	4601703
89772678	89772700	8	-	27760321	MV411	viability	CACTATACATTATCTGCAAAGG	RIPK2	ENSG00000104312	2.1432687413842784	[45,48]	[0,346]	9	hSpCas9	negative selection	4601704
89772753	89772775	8	-	27760321	MV411	viability	AGATCATACGTGCTCGGTGAGG	RIPK2	ENSG00000104312	-0.027706631830954953	[517,560]	[271,470]	0	hSpCas9	negative selection	4601705
89758165	89758187	8	-	27760321	HL60	viability	GACGCGCCAGTCTGCGTGGCGG	RIPK2	ENSG00000104312	0.17142522529950188	[987,860]	[731,971]	2	hSpCas9	negative selection	4685164
89765353	89765375	8	-	27760321	HL60	viability	TCAATGGCCAAGCAACATCAGG	RIPK2	ENSG00000104312	0.7091420980812346	[309,224]	[361,344]	7	hSpCas9	negative selection	4685165
89769810	89769832	8	-	27760321	HL60	viability	GCTACTTCGTGACTGTGAGAGG	RIPK2	ENSG00000104312	0.2510580410891966	[602,509]	[590,483]	3	hSpCas9	negative selection	4685166
89772678	89772700	8	-	27760321	HL60	viability	CACTATACATTATCTGCAAAGG	RIPK2	ENSG00000104312	-0.7629380431718888	[45,48]	[22,22]	-7	hSpCas9	negative selection	4685167
89772753	89772775	8	-	27760321	HL60	viability	AGATCATACGTGCTCGGTGAGG	RIPK2	ENSG00000104312	0.1620115791941693	[517,560]	[456,537]	2	hSpCas9	negative selection	4685168
89758165	89758187	8	-	27760321	HT1080	viability	GACGCGCCAGTCTGCGTGGCGG	RIPK2	ENSG00000104312	0.3199922071359953	[860,671]	[405,353]	1	hSpCas9	negative selection	4768627
89765353	89765375	8	-	27760321	HT1080	viability	TCAATGGCCAAGCAACATCAGG	RIPK2	ENSG00000104312	2.428128339819472	[224,175]	[417,442]	9	hSpCas9	negative selection	4768628
89769810	89769832	8	-	27760321	HT1080	viability	GCTACTTCGTGACTGTGAGAGG	RIPK2	ENSG00000104312	2.044510691025706	[509,397]	[937,535]	9	hSpCas9	negative selection	4768629
89772678	89772700	8	-	27760321	HT1080	viability	CACTATACATTATCTGCAAAGG	RIPK2	ENSG00000104312	4.208657622905669	[48,37]	[378,255]	9	hSpCas9	negative selection	4768630
89772753	89772775	8	-	27760321	HT1080	viability	AGATCATACGTGCTCGGTGAGG	RIPK2	ENSG00000104312	-0.5866889118192731	[560,437]	[121,143]	-3	hSpCas9	negative selection	4768631
89758165	89758187	8	-	27760321	HT29	viability after 7 days	GACGCGCCAGTCTGCGTGGCGG	RIPK2	ENSG00000104312	-0.11244320407801733	[860,671]	[1118,761,882]	-2	hSpCas9	negative selection	4852090
89765353	89765375	8	-	27760321	HT29	viability after 7 days	TCAATGGCCAAGCAACATCAGG	RIPK2	ENSG00000104312	0.3779524014711738	[224,175]	[364,470,177]	6	hSpCas9	negative selection	4852091
89769810	89769832	8	-	27760321	HT29	viability after 7 days	GCTACTTCGTGACTGTGAGAGG	RIPK2	ENSG00000104312	0.15409663545766045	[509,397]	[780,715,474]	2	hSpCas9	negative selection	4852092
89772678	89772700	8	-	27760321	HT29	viability after 7 days	CACTATACATTATCTGCAAAGG	RIPK2	ENSG00000104312	-0.48025530097015423	[48,37]	[67,42,13]	-6	hSpCas9	negative selection	4852093
89772753	89772775	8	-	27760321	HT29	viability after 7 days	AGATCATACGTGCTCGGTGAGG	RIPK2	ENSG00000104312	-0.15989942389130118	[560,437]	[663,483,587]	-2	hSpCas9	negative selection	4852094
89758165	89758187	8	-	27760321	HT29	viability after 25 days	GACGCGCCAGTCTGCGTGGCGG	RIPK2	ENSG00000104312	0.13706934032627882	[860,671]	[1057,950,862]	1	hSpCas9	negative selection	4935553
89765353	89765375	8	-	27760321	HT29	viability after 25 days	TCAATGGCCAAGCAACATCAGG	RIPK2	ENSG00000104312	1.0308902022307054	[224,175]	[458,525,413]	9	hSpCas9	negative selection	4935554
89769810	89769832	8	-	27760321	HT29	viability after 25 days	GCTACTTCGTGACTGTGAGAGG	RIPK2	ENSG00000104312	0.22655834645514888	[509,397]	[453,724,655]	2	hSpCas9	negative selection	4935555
89772678	89772700	8	-	27760321	HT29	viability after 25 days	CACTATACATTATCTGCAAAGG	RIPK2	ENSG00000104312	-1.2225995285275388	[48,37]	[30,12,18]	-7	hSpCas9	negative selection	4935556
89772753	89772775	8	-	27760321	HT29	viability after 25 days	AGATCATACGTGCTCGGTGAGG	RIPK2	ENSG00000104312	-0.12389069824835935	[560,437]	[415,625,536]	-1	hSpCas9	negative selection	4935557
89758165	89758187	8	-	27760321	HT29	viability after 22 days	GACGCGCCAGTCTGCGTGGCGG	RIPK2	ENSG00000104312	0.24801836585035542	[860,671]	[1284,880,983]	2	hSpCas9	negative selection	5019016
89765353	89765375	8	-	27760321	HT29	viability after 22 days	TCAATGGCCAAGCAACATCAGG	RIPK2	ENSG00000104312	1.3086904272601096	[224,175]	[725,694,294]	9	hSpCas9	negative selection	5019017
89769810	89769832	8	-	27760321	HT29	viability after 22 days	GCTACTTCGTGACTGTGAGAGG	RIPK2	ENSG00000104312	0.3200950879669669	[509,397]	[599,829,535]	3	hSpCas9	negative selection	5019018
89772678	89772700	8	-	27760321	HT29	viability after 22 days	CACTATACATTATCTGCAAAGG	RIPK2	ENSG00000104312	0.3493842578729067	[48,37]	[81,7,101]	4	hSpCas9	negative selection	5019019
89772753	89772775	8	-	27760321	HT29	viability after 22 days	AGATCATACGTGCTCGGTGAGG	RIPK2	ENSG00000104312	0.176984254754397	[560,437]	[442,672,849]	1	hSpCas9	negative selection	5019020
89758165	89758187	8	-	27760321	HT29	viability after 19 days	GACGCGCCAGTCTGCGTGGCGG	RIPK2	ENSG00000104312	-0.0975054754733633	[860,671]	[1085,837,570]	-1	hSpCas9	negative selection	5102479
89765353	89765375	8	-	27760321	HT29	viability after 19 days	TCAATGGCCAAGCAACATCAGG	RIPK2	ENSG00000104312	1.1396368787332345	[224,175]	[257,976,263]	9	hSpCas9	negative selection	5102480
89769810	89769832	8	-	27760321	HT29	viability after 19 days	GCTACTTCGTGACTGTGAGAGG	RIPK2	ENSG00000104312	0.4254386035817423	[509,397]	[755,1056,299]	4	hSpCas9	negative selection	5102481
89772678	89772700	8	-	27760321	HT29	viability after 19 days	CACTATACATTATCTGCAAAGG	RIPK2	ENSG00000104312	0.4790299787131458	[48,37]	[92,37,78]	5	hSpCas9	negative selection	5102482
89772753	89772775	8	-	27760321	HT29	viability after 19 days	AGATCATACGTGCTCGGTGAGG	RIPK2	ENSG00000104312	0.05426491339197376	[560,437]	[410,539,800]	0	hSpCas9	negative selection	5102483
89758165	89758187	8	-	27760321	HT29	viability after 16 days	GACGCGCCAGTCTGCGTGGCGG	RIPK2	ENSG00000104312	0.28250446181882394	[860,671]	[1184,1020,936]	3	hSpCas9	negative selection	5185942
89765353	89765375	8	-	27760321	HT29	viability after 16 days	TCAATGGCCAAGCAACATCAGG	RIPK2	ENSG00000104312	0.4338839194833753	[224,175]	[216,418,261]	5	hSpCas9	negative selection	5185943
89769810	89769832	8	-	27760321	HT29	viability after 16 days	GCTACTTCGTGACTGTGAGAGG	RIPK2	ENSG00000104312	0.08397138694191919	[509,397]	[647,476,501]	0	hSpCas9	negative selection	5185944
89772678	89772700	8	-	27760321	HT29	viability after 16 days	CACTATACATTATCTGCAAAGG	RIPK2	ENSG00000104312	-0.9096852475348491	[48,37]	[50,27,0]	-6	hSpCas9	negative selection	5185945
89772753	89772775	8	-	27760321	HT29	viability after 16 days	AGATCATACGTGCTCGGTGAGG	RIPK2	ENSG00000104312	0.046623930667003155	[560,437]	[797,400,557]	0	hSpCas9	negative selection	5185946
89758165	89758187	8	-	27760321	HT29	viability after 13 days	GACGCGCCAGTCTGCGTGGCGG	RIPK2	ENSG00000104312	0.17696529343912504	[860,671]	[1477,675,868]	2	hSpCas9	negative selection	5269405
89765353	89765375	8	-	27760321	HT29	viability after 13 days	TCAATGGCCAAGCAACATCAGG	RIPK2	ENSG00000104312	0.6429426971830497	[224,175]	[296,482,312]	8	hSpCas9	negative selection	5269406
89769810	89769832	8	-	27760321	HT29	viability after 13 days	GCTACTTCGTGACTGTGAGAGG	RIPK2	ENSG00000104312	-0.11832205952784655	[509,397]	[381,523,545]	-1	hSpCas9	negative selection	5269407
89772678	89772700	8	-	27760321	HT29	viability after 13 days	CACTATACATTATCTGCAAAGG	RIPK2	ENSG00000104312	-0.2677077649545714	[48,37]	[14,89,21]	-3	hSpCas9	negative selection	5269408
89772753	89772775	8	-	27760321	HT29	viability after 13 days	AGATCATACGTGCTCGGTGAGG	RIPK2	ENSG00000104312	-0.027770437612726018	[560,437]	[461,564,671]	0	hSpCas9	negative selection	5269409
89758165	89758187	8	-	27760321	HT29	viability after 10 days	GACGCGCCAGTCTGCGTGGCGG	RIPK2	ENSG00000104312	0.2680750518419681	[860,671]	[1538,1096,826]	3	hSpCas9	negative selection	5352868
89765353	89765375	8	-	27760321	HT29	viability after 10 days	TCAATGGCCAAGCAACATCAGG	RIPK2	ENSG00000104312	0.7835362701033654	[224,175]	[484,489,321]	9	hSpCas9	negative selection	5352869
89769810	89769832	8	-	27760321	HT29	viability after 10 days	GCTACTTCGTGACTGTGAGAGG	RIPK2	ENSG00000104312	-0.10370442820782119	[509,397]	[370,687,527]	-1	hSpCas9	negative selection	5352870
89772678	89772700	8	-	27760321	HT29	viability after 10 days	CACTATACATTATCTGCAAAGG	RIPK2	ENSG00000104312	0.10477093986749919	[48,37]	[79,5,86]	1	hSpCas9	negative selection	5352871
89772753	89772775	8	-	27760321	HT29	viability after 10 days	AGATCATACGTGCTCGGTGAGG	RIPK2	ENSG00000104312	-0.2416213361599341	[560,437]	[571,659,357]	-3	hSpCas9	negative selection	5352872
89758165	89758187	8	-	27760321	MOLM13	viability	GACGCGCCAGTCTGCGTGGCGG	RIPK2	ENSG00000104312	-0.6218716361049638	[987,860]	[167,482]	-4	hSpCas9	negative selection	5436331
89765353	89765375	8	-	27760321	MOLM13	viability	TCAATGGCCAAGCAACATCAGG	RIPK2	ENSG00000104312	0.43201413209759665	[309,224]	[320,99]	3	hSpCas9	negative selection	5436332
89769810	89769832	8	-	27760321	MOLM13	viability	GCTACTTCGTGACTGTGAGAGG	RIPK2	ENSG00000104312	0.5329184407076557	[602,509]	[685,253]	3	hSpCas9	negative selection	5436333
89772678	89772700	8	-	27760321	MOLM13	viability	CACTATACATTATCTGCAAAGG	RIPK2	ENSG00000104312	-3.8117081486945024	[45,48]	[2,0]	-9	hSpCas9	negative selection	5436334
89772753	89772775	8	-	27760321	MOLM13	viability	AGATCATACGTGCTCGGTGAGG	RIPK2	ENSG00000104312	-0.39606619246258173	[517,560]	[483,18]	-3	hSpCas9	negative selection	5436335
89769905	89769928	8	-	27260156	BXPC3	viability	ATATATATCGTGCTTGATACTGG	RIPK2	ENSG00000104312	-0.34192083972929443	[827]	[660,619,639,829]	-6	hSpCas9	negative selection	5567410
89765368	89765391	8	-	27260156	BXPC3	viability	TGCAGGATGCGAAATCTCAATGG	RIPK2	ENSG00000104312	0.4288927983199802	[10]	[19,14,12,12]	8	hSpCas9	negative selection	5567411
89769908	89769931	8	+	27260156	BXPC3	viability	GTATCAAGCACGATATATATAGG	RIPK2	ENSG00000104312	-0.15638318056581374	[623]	[575,539,592,638]	-4	hSpCas9	negative selection	5567412
89765400	89765423	8	-	27260156	BXPC3	viability	TGTGCAGGTAATTTACACCAAGG	RIPK2	ENSG00000104312	0.338503950532709	[716]	[767,845,992,1240]	7	hSpCas9	negative selection	5631664
89771737	89771760	8	+	27260156	BXPC3	viability	ACAGCTATGCAGTTATCACATGG	RIPK2	ENSG00000104312	0.15642755470650638	[487]	[491,518,617,665]	3	hSpCas9	negative selection	5631665
89769868	89769891	8	+	27260156	BXPC3	viability	CCACCTGAAAACTATGAACCTGG	RIPK2	ENSG00000104312	0.017920556623676503	[409]	[509,343,402,477]	0	hSpCas9	negative selection	5631666
89769905	89769928	8	-	27260156	A673	viability	ATATATATCGTGCTTGATACTGG	RIPK2	ENSG00000104312	-0.35464894349221143	[827]	[934,672,696,827]	-7	hSpCas9	negative selection	5688661
89765368	89765391	8	-	27260156	A673	viability	TGCAGGATGCGAAATCTCAATGG	RIPK2	ENSG00000104312	0.9694879453263399	[10]	[29,30,28,12]	9	hSpCas9	negative selection	5688662
89769908	89769931	8	+	27260156	A673	viability	GTATCAAGCACGATATATATAGG	RIPK2	ENSG00000104312	-0.37337855918218293	[623]	[547,696,551,504]	-7	hSpCas9	negative selection	5688663
89765400	89765423	8	-	27260156	A673	viability	TGTGCAGGTAATTTACACCAAGG	RIPK2	ENSG00000104312	0.2372715118035743	[716]	[1044,972,1009,1034]	5	hSpCas9	negative selection	5752915
89771737	89771760	8	+	27260156	A673	viability	ACAGCTATGCAGTTATCACATGG	RIPK2	ENSG00000104312	-0.011154420775354994	[487]	[510,675,535,591]	0	hSpCas9	negative selection	5752916
89769868	89769891	8	+	27260156	A673	viability	CCACCTGAAAACTATGAACCTGG	RIPK2	ENSG00000104312	0.023227414944153646	[409]	[559,450,516,478]	0	hSpCas9	negative selection	5752917
89769905	89769928	8	-	27260156	A375	viability	ATATATATCGTGCTTGATACTGG	RIPK2	ENSG00000104312	-0.2803289805023118	[827]	[905,952,819,554]	-4	hSpCas9	negative selection	5809912
89765368	89765391	8	-	27260156	A375	viability	TGCAGGATGCGAAATCTCAATGG	RIPK2	ENSG00000104312	1.786751722449071	[10]	[13,59,105,3]	9	hSpCas9	negative selection	5809913
89769908	89769931	8	+	27260156	A375	viability	GTATCAAGCACGATATATATAGG	RIPK2	ENSG00000104312	-0.34094388050937036	[623]	[702,752,486,402]	-5	hSpCas9	negative selection	5809914
89765400	89765423	8	-	27260156	A375	viability	TGTGCAGGTAATTTACACCAAGG	RIPK2	ENSG00000104312	0.15165710060714133	[716]	[776,1306,793,894]	2	hSpCas9	negative selection	5874166
89771737	89771760	8	+	27260156	A375	viability	ACAGCTATGCAGTTATCACATGG	RIPK2	ENSG00000104312	0.0014304788874522495	[487]	[700,697,424,484]	0	hSpCas9	negative selection	5874167
89769868	89769891	8	+	27260156	A375	viability	CCACCTGAAAACTATGAACCTGG	RIPK2	ENSG00000104312	0.31828510172274915	[409]	[499,609,789,498]	4	hSpCas9	negative selection	5874168
89769905	89769928	8	-	27260156	COLO741	viability	ATATATATCGTGCTTGATACTGG	RIPK2	ENSG00000104312	-0.40295904645223213	[827]	[1139,671,627]	-7	hSpCas9	negative selection	5931163
89765368	89765391	8	-	27260156	COLO741	viability	TGCAGGATGCGAAATCTCAATGG	RIPK2	ENSG00000104312	1.4579479186846873	[10]	[80,23,15]	9	hSpCas9	negative selection	5931164
89769908	89769931	8	+	27260156	COLO741	viability	GTATCAAGCACGATATATATAGG	RIPK2	ENSG00000104312	-0.19864416568947066	[623]	[621,792,663]	-4	hSpCas9	negative selection	5931165
89765400	89765423	8	-	27260156	COLO741	viability	TGTGCAGGTAATTTACACCAAGG	RIPK2	ENSG00000104312	0.15612575676642404	[716]	[1195,1001,886]	3	hSpCas9	negative selection	5995417
89771737	89771760	8	+	27260156	COLO741	viability	ACAGCTATGCAGTTATCACATGG	RIPK2	ENSG00000104312	-0.18755640696164189	[487]	[485,557,588]	-4	hSpCas9	negative selection	5995418
89769868	89769891	8	+	27260156	COLO741	viability	CCACCTGAAAACTATGAACCTGG	RIPK2	ENSG00000104312	-0.17913607559258618	[409]	[511,400,476]	-4	hSpCas9	negative selection	5995419
89769905	89769928	8	-	27260156	CAL120	viability	ATATATATCGTGCTTGATACTGG	RIPK2	ENSG00000104312	-0.6530661175914925	[827]	[703,794,476]	-7	hSpCas9	negative selection	6052414
89765368	89765391	8	-	27260156	CAL120	viability	TGCAGGATGCGAAATCTCAATGG	RIPK2	ENSG00000104312	-0.06654113928301175	[10]	[5,10,20]	-1	hSpCas9	negative selection	6052415
89769908	89769931	8	+	27260156	CAL120	viability	GTATCAAGCACGATATATATAGG	RIPK2	ENSG00000104312	0.08404353055557318	[623]	[915,918,650]	1	hSpCas9	negative selection	6052416
89765400	89765423	8	-	27260156	CAL120	viability	TGTGCAGGTAATTTACACCAAGG	RIPK2	ENSG00000104312	0.24606727550649232	[716]	[1264,985,955]	3	hSpCas9	negative selection	6116668
89771737	89771760	8	+	27260156	CAL120	viability	ACAGCTATGCAGTTATCACATGG	RIPK2	ENSG00000104312	-0.22940789781911966	[487]	[475,473,595]	-3	hSpCas9	negative selection	6116669
89769868	89769891	8	+	27260156	CAL120	viability	CCACCTGAAAACTATGAACCTGG	RIPK2	ENSG00000104312	0.10396335368095769	[409]	[583,455,608]	1	hSpCas9	negative selection	6116670
89769905	89769928	8	-	27260156	CADOES1	viability	ATATATATCGTGCTTGATACTGG	RIPK2	ENSG00000104312	-0.10121297639442728	[827]	[594,847,640,790]	-2	hSpCas9	negative selection	6173665
89765368	89765391	8	-	27260156	CADOES1	viability	TGCAGGATGCGAAATCTCAATGG	RIPK2	ENSG00000104312	-0.6416357315966339	[10]	[13,4,5,0]	-8	hSpCas9	negative selection	6173666
89769908	89769931	8	+	27260156	CADOES1	viability	GTATCAAGCACGATATATATAGG	RIPK2	ENSG00000104312	-0.32186712112219135	[623]	[382,397,541,536]	-5	hSpCas9	negative selection	6173667
89765400	89765423	8	-	27260156	CADOES1	viability	TGTGCAGGTAATTTACACCAAGG	RIPK2	ENSG00000104312	0.2108179783607369	[716]	[723,797,876,684]	3	hSpCas9	negative selection	6237919
89771737	89771760	8	+	27260156	CADOES1	viability	ACAGCTATGCAGTTATCACATGG	RIPK2	ENSG00000104312	-0.2975531865699924	[487]	[419,352,282,422]	-5	hSpCas9	negative selection	6237920
89769868	89769891	8	+	27260156	CADOES1	viability	CCACCTGAAAACTATGAACCTGG	RIPK2	ENSG00000104312	0.155570388149053	[409]	[240,459,432,570]	2	hSpCas9	negative selection	6237921
89769905	89769928	8	-	27260156	EWS502	viability	ATATATATCGTGCTTGATACTGG	RIPK2	ENSG00000104312	-0.25709673871425753	[827]	[655,654,798,843]	-4	hSpCas9	negative selection	6294916
89765368	89765391	8	-	27260156	EWS502	viability	TGCAGGATGCGAAATCTCAATGG	RIPK2	ENSG00000104312	-0.24775866231952648	[10]	[11,1,4,20]	-4	hSpCas9	negative selection	6294917
89769908	89769931	8	+	27260156	EWS502	viability	GTATCAAGCACGATATATATAGG	RIPK2	ENSG00000104312	-0.11604504788759623	[623]	[451,609,844,547]	-2	hSpCas9	negative selection	6294918
89765400	89765423	8	-	27260156	EWS502	viability	TGTGCAGGTAATTTACACCAAGG	RIPK2	ENSG00000104312	-0.041978125331944005	[716]	[627,725,636,986]	0	hSpCas9	negative selection	6359170
89771737	89771760	8	+	27260156	EWS502	viability	ACAGCTATGCAGTTATCACATGG	RIPK2	ENSG00000104312	-0.18179036571964904	[487]	[448,476,481,409]	-3	hSpCas9	negative selection	6359171
89769868	89769891	8	+	27260156	EWS502	viability	CCACCTGAAAACTATGAACCTGG	RIPK2	ENSG00000104312	0.08913377045928889	[409]	[432,484,542,382]	1	hSpCas9	negative selection	6359172
89769905	89769928	8	-	27260156	EW8	viability	ATATATATCGTGCTTGATACTGG	RIPK2	ENSG00000104312	-0.24019322966221812	[827]	[693,695,507,397]	-4	hSpCas9	negative selection	6416167
89765368	89765391	8	-	27260156	EW8	viability	TGCAGGATGCGAAATCTCAATGG	RIPK2	ENSG00000104312	1.8342599979268988	[10]	[17,78,18,11]	9	hSpCas9	negative selection	6416168
89769908	89769931	8	+	27260156	EW8	viability	GTATCAAGCACGATATATATAGG	RIPK2	ENSG00000104312	-0.07029743130545946	[623]	[629,324,497,484]	-1	hSpCas9	negative selection	6416169
89765400	89765423	8	-	27260156	EW8	viability	TGTGCAGGTAATTTACACCAAGG	RIPK2	ENSG00000104312	0.16931282775068035	[716]	[635,710,642,621]	3	hSpCas9	negative selection	6480421
89771737	89771760	8	+	27260156	EW8	viability	ACAGCTATGCAGTTATCACATGG	RIPK2	ENSG00000104312	-0.014601984778066977	[487]	[499,323,334,426]	0	hSpCas9	negative selection	6480422
89769868	89769891	8	+	27260156	EW8	viability	CCACCTGAAAACTATGAACCTGG	RIPK2	ENSG00000104312	0.31079803858047406	[409]	[396,494,335,430]	5	hSpCas9	negative selection	6480423
89769905	89769928	8	-	27260156	CORL105	viability	ATATATATCGTGCTTGATACTGG	RIPK2	ENSG00000104312	-0.2641541890043444	[827]	[1027,643,973,619]	-5	hSpCas9	negative selection	6537418
89765368	89765391	8	-	27260156	CORL105	viability	TGCAGGATGCGAAATCTCAATGG	RIPK2	ENSG00000104312	0.09640970095353651	[10]	[9,10,13,19]	1	hSpCas9	negative selection	6537419
89769908	89769931	8	+	27260156	CORL105	viability	GTATCAAGCACGATATATATAGG	RIPK2	ENSG00000104312	0.20191781270730763	[623]	[915,927,994,547]	4	hSpCas9	negative selection	6537420
89765400	89765423	8	-	27260156	CORL105	viability	TGTGCAGGTAATTTACACCAAGG	RIPK2	ENSG00000104312	0.3426159808765179	[716]	[1164,899,1060,1136]	6	hSpCas9	negative selection	6601672
89771737	89771760	8	+	27260156	CORL105	viability	ACAGCTATGCAGTTATCACATGG	RIPK2	ENSG00000104312	0.2011272463419941	[487]	[578,565,892,624]	4	hSpCas9	negative selection	6601673
89769868	89769891	8	+	27260156	CORL105	viability	CCACCTGAAAACTATGAACCTGG	RIPK2	ENSG00000104312	0.064269496624937	[409]	[486,525,518,476]	1	hSpCas9	negative selection	6601674
89769905	89769928	8	-	27260156	HS294T	viability	ATATATATCGTGCTTGATACTGG	RIPK2	ENSG00000104312	-0.3570945801714694	[827]	[204,235,286,280]	-5	hSpCas9	negative selection	6658669
89765368	89765391	8	-	27260156	HS294T	viability	TGCAGGATGCGAAATCTCAATGG	RIPK2	ENSG00000104312	1.2161307931049388	[10]	[3,21,6,5]	9	hSpCas9	negative selection	6658670
89769908	89769931	8	+	27260156	HS294T	viability	GTATCAAGCACGATATATATAGG	RIPK2	ENSG00000104312	0.3062350605240965	[623]	[238,216,410,340]	4	hSpCas9	negative selection	6658671
89765400	89765423	8	-	27260156	HS294T	viability	TGTGCAGGTAATTTACACCAAGG	RIPK2	ENSG00000104312	-0.0935222055099284	[716]	[144,283,263,374]	-1	hSpCas9	negative selection	6722923
89771737	89771760	8	+	27260156	HS294T	viability	ACAGCTATGCAGTTATCACATGG	RIPK2	ENSG00000104312	0.4325976880909113	[487]	[277,275,174,291]	6	hSpCas9	negative selection	6722924
89769868	89769891	8	+	27260156	HS294T	viability	CCACCTGAAAACTATGAACCTGG	RIPK2	ENSG00000104312	-0.19569335908218785	[409]	[117,146,170,114]	-3	hSpCas9	negative selection	6722925
89769905	89769928	8	-	27260156	HCC44	viability	ATATATATCGTGCTTGATACTGG	RIPK2	ENSG00000104312	-0.35676382220396513	[827]	[975,750,661,543]	-5	hSpCas9	negative selection	6779920
89765368	89765391	8	-	27260156	HCC44	viability	TGCAGGATGCGAAATCTCAATGG	RIPK2	ENSG00000104312	-0.5392600158322933	[10]	[17,0,12,4]	-7	hSpCas9	negative selection	6779921
89769908	89769931	8	+	27260156	HCC44	viability	GTATCAAGCACGATATATATAGG	RIPK2	ENSG00000104312	-0.20772573490432553	[623]	[602,453,795,638]	-3	hSpCas9	negative selection	6779922
89765400	89765423	8	-	27260156	HCC44	viability	TGTGCAGGTAATTTACACCAAGG	RIPK2	ENSG00000104312	0.27843136598379103	[716]	[901,894,1465,758]	4	hSpCas9	negative selection	6844174
89771737	89771760	8	+	27260156	HCC44	viability	ACAGCTATGCAGTTATCACATGG	RIPK2	ENSG00000104312	-0.10113404327780494	[487]	[579,438,669,411]	-2	hSpCas9	negative selection	6844175
89769868	89769891	8	+	27260156	HCC44	viability	CCACCTGAAAACTATGAACCTGG	RIPK2	ENSG00000104312	-0.17298892990247658	[409]	[433,264,555,433]	-3	hSpCas9	negative selection	6844176
89769905	89769928	8	-	27260156	G402	viability	ATATATATCGTGCTTGATACTGG	RIPK2	ENSG00000104312	-0.07177763894698597	[827]	[1194,848,997,832]	-1	hSpCas9	negative selection	6901171
89765368	89765391	8	-	27260156	G402	viability	TGCAGGATGCGAAATCTCAATGG	RIPK2	ENSG00000104312	-0.3483208869218375	[10]	[16,1,0,21]	-4	hSpCas9	negative selection	6901172
89769908	89769931	8	+	27260156	G402	viability	GTATCAAGCACGATATATATAGG	RIPK2	ENSG00000104312	-0.07793731468569215	[623]	[690,1012,655,543]	-1	hSpCas9	negative selection	6901173
89765400	89765423	8	-	27260156	G402	viability	TGTGCAGGTAATTTACACCAAGG	RIPK2	ENSG00000104312	0.34463710571301986	[716]	[1492,871,1517,621]	4	hSpCas9	negative selection	6965425
89771737	89771760	8	+	27260156	G402	viability	ACAGCTATGCAGTTATCACATGG	RIPK2	ENSG00000104312	0.36023702532252466	[487]	[928,301,1514,326]	4	hSpCas9	negative selection	6965426
89769868	89769891	8	+	27260156	G402	viability	CCACCTGAAAACTATGAACCTGG	RIPK2	ENSG00000104312	1.2348038767681377	[409]	[753,703,1823,1326]	9	hSpCas9	negative selection	6965427
89769905	89769928	8	-	27260156	L33	viability	ATATATATCGTGCTTGATACTGG	RIPK2	ENSG00000104312	-0.34545092401475347	[827]	[675,242,422,663]	-7	hSpCas9	negative selection	7022422
89765368	89765391	8	-	27260156	L33	viability	TGCAGGATGCGAAATCTCAATGG	RIPK2	ENSG00000104312	1.595285547870172	[10]	[42,5,21,39]	9	hSpCas9	negative selection	7022423
89769908	89769931	8	+	27260156	L33	viability	GTATCAAGCACGATATATATAGG	RIPK2	ENSG00000104312	0.08462579932191355	[623]	[793,291,374,540]	2	hSpCas9	negative selection	7022424
89765400	89765423	8	-	27260156	L33	viability	TGTGCAGGTAATTTACACCAAGG	RIPK2	ENSG00000104312	-0.07416276857857251	[716]	[558,329,462,626]	-2	hSpCas9	negative selection	7086676
89771737	89771760	8	+	27260156	L33	viability	ACAGCTATGCAGTTATCACATGG	RIPK2	ENSG00000104312	0.014403742821942227	[487]	[474,186,307,549]	0	hSpCas9	negative selection	7086677
89769868	89769891	8	+	27260156	L33	viability	CCACCTGAAAACTATGAACCTGG	RIPK2	ENSG00000104312	0.026676537194292776	[409]	[330,192,239,487]	0	hSpCas9	negative selection	7086678
89769905	89769928	8	-	27260156	K562	viability	ATATATATCGTGCTTGATACTGG	RIPK2	ENSG00000104312	-0.08418239109828396	[827]	[741,507,670,826]	-1	hSpCas9	negative selection	7143673
89765368	89765391	8	-	27260156	K562	viability	TGCAGGATGCGAAATCTCAATGG	RIPK2	ENSG00000104312	-1.0372172200824776	[10]	[1,3,0,10]	-8	hSpCas9	negative selection	7143674
89769908	89769931	8	+	27260156	K562	viability	GTATCAAGCACGATATATATAGG	RIPK2	ENSG00000104312	0.2957312970920702	[623]	[747,627,663,678]	3	hSpCas9	negative selection	7143675
89765400	89765423	8	-	27260156	K562	viability	TGTGCAGGTAATTTACACCAAGG	RIPK2	ENSG00000104312	0.25050228049286516	[716]	[1167,652,552,686]	3	hSpCas9	negative selection	7207927
89771737	89771760	8	+	27260156	K562	viability	ACAGCTATGCAGTTATCACATGG	RIPK2	ENSG00000104312	0.09237959337852353	[487]	[369,471,525,468]	1	hSpCas9	negative selection	7207928
89769868	89769891	8	+	27260156	K562	viability	CCACCTGAAAACTATGAACCTGG	RIPK2	ENSG00000104312	0.3454433185630983	[409]	[556,458,246,577]	4	hSpCas9	negative selection	7207929
89769905	89769928	8	-	27260156	HT29	viability	ATATATATCGTGCTTGATACTGG	RIPK2	ENSG00000104312	-0.31870304239419445	[827]	[972,892,700,689]	-6	hSpCas9	negative selection	7264924
89765368	89765391	8	-	27260156	HT29	viability	TGCAGGATGCGAAATCTCAATGG	RIPK2	ENSG00000104312	0.8196383449118478	[10]	[25,43,27,0]	9	hSpCas9	negative selection	7264925
89769908	89769931	8	+	27260156	HT29	viability	GTATCAAGCACGATATATATAGG	RIPK2	ENSG00000104312	-0.28298020439614213	[623]	[745,709,506,551]	-5	hSpCas9	negative selection	7264926
89765400	89765423	8	-	27260156	HT29	viability	TGTGCAGGTAATTTACACCAAGG	RIPK2	ENSG00000104312	0.2742378160782504	[716]	[1012,1498,797,946]	5	hSpCas9	negative selection	7329178
89771737	89771760	8	+	27260156	HT29	viability	ACAGCTATGCAGTTATCACATGG	RIPK2	ENSG00000104312	-0.15708825928607956	[487]	[477,454,518,646]	-3	hSpCas9	negative selection	7329179
89769868	89769891	8	+	27260156	HT29	viability	CCACCTGAAAACTATGAACCTGG	RIPK2	ENSG00000104312	0.20618826595273998	[409]	[563,734,563,459]	4	hSpCas9	negative selection	7329180
89769905	89769928	8	-	27260156	MHHES1	viability	ATATATATCGTGCTTGATACTGG	RIPK2	ENSG00000104312	-0.31105632138787953	[827]	[1004,623,847,572]	-5	hSpCas9	negative selection	7386175
89765368	89765391	8	-	27260156	MHHES1	viability	TGCAGGATGCGAAATCTCAATGG	RIPK2	ENSG00000104312	-0.629212153011161	[10]	[1,0,16,9]	-8	hSpCas9	negative selection	7386176
89769908	89769931	8	+	27260156	MHHES1	viability	GTATCAAGCACGATATATATAGG	RIPK2	ENSG00000104312	0.19973101310873992	[623]	[1030,972,757,551]	3	hSpCas9	negative selection	7386177
89765400	89765423	8	-	27260156	MHHES1	viability	TGTGCAGGTAATTTACACCAAGG	RIPK2	ENSG00000104312	-0.02564602989222775	[716]	[983,662,667,837]	0	hSpCas9	negative selection	7450429
89771737	89771760	8	+	27260156	MHHES1	viability	ACAGCTATGCAGTTATCACATGG	RIPK2	ENSG00000104312	0.11132008963267581	[487]	[721,594,688,413]	2	hSpCas9	negative selection	7450430
89769868	89769891	8	+	27260156	MHHES1	viability	CCACCTGAAAACTATGAACCTGG	RIPK2	ENSG00000104312	0.4687347658230847	[409]	[633,484,884,544]	8	hSpCas9	negative selection	7450431
89769905	89769928	8	-	27260156	MEWO	viability	ATATATATCGTGCTTGATACTGG	RIPK2	ENSG00000104312	-0.49688969958198637	[827]	[713,481,482]	-8	hSpCas9	negative selection	7507426
89765368	89765391	8	-	27260156	MEWO	viability	TGCAGGATGCGAAATCTCAATGG	RIPK2	ENSG00000104312	0.3132551067914102	[10]	[0,27,6]	6	hSpCas9	negative selection	7507427
89769908	89769931	8	+	27260156	MEWO	viability	GTATCAAGCACGATATATATAGG	RIPK2	ENSG00000104312	-0.14944609487471738	[623]	[539,640,399]	-3	hSpCas9	negative selection	7507428
89765400	89765423	8	-	27260156	MEWO	viability	TGTGCAGGTAATTTACACCAAGG	RIPK2	ENSG00000104312	0.2093086638975885	[716]	[620,874,799]	4	hSpCas9	negative selection	7571680
89771737	89771760	8	+	27260156	MEWO	viability	ACAGCTATGCAGTTATCACATGG	RIPK2	ENSG00000104312	0.03729814154270695	[487]	[588,421,417]	0	hSpCas9	negative selection	7571681
89769868	89769891	8	+	27260156	MEWO	viability	CCACCTGAAAACTATGAACCTGG	RIPK2	ENSG00000104312	-0.1106216556445668	[409]	[499,306,286]	-2	hSpCas9	negative selection	7571682
89769905	89769928	8	-	27260156	LNCAPCLONEFGC	viability	ATATATATCGTGCTTGATACTGG	RIPK2	ENSG00000104312	-0.42716614012715504	[827]	[627,521,591,494]	-6	hSpCas9	negative selection	7628677
89765368	89765391	8	-	27260156	LNCAPCLONEFGC	viability	TGCAGGATGCGAAATCTCAATGG	RIPK2	ENSG00000104312	0.4231758243648356	[10]	[9,4,12,25]	6	hSpCas9	negative selection	7628678
89769908	89769931	8	+	27260156	LNCAPCLONEFGC	viability	GTATCAAGCACGATATATATAGG	RIPK2	ENSG00000104312	-0.3696392940764921	[623]	[332,542,499,377]	-5	hSpCas9	negative selection	7628679
89765400	89765423	8	-	27260156	LNCAPCLONEFGC	viability	TGTGCAGGTAATTTACACCAAGG	RIPK2	ENSG00000104312	0.3675761994414254	[716]	[752,885,926,796]	6	hSpCas9	negative selection	7692931
89771737	89771760	8	+	27260156	LNCAPCLONEFGC	viability	ACAGCTATGCAGTTATCACATGG	RIPK2	ENSG00000104312	-0.1804218336637708	[487]	[350,258,554,428]	-3	hSpCas9	negative selection	7692932
89769868	89769891	8	+	27260156	LNCAPCLONEFGC	viability	CCACCTGAAAACTATGAACCTGG	RIPK2	ENSG00000104312	0.43906950487262664	[409]	[471,492,664,408]	7	hSpCas9	negative selection	7692933
89769905	89769928	8	-	27260156	PANC0327	viability	ATATATATCGTGCTTGATACTGG	RIPK2	ENSG00000104312	-0.5228304342010772	[827]	[581,505,471,493]	-6	hSpCas9	negative selection	7749928
89765368	89765391	8	-	27260156	PANC0327	viability	TGCAGGATGCGAAATCTCAATGG	RIPK2	ENSG00000104312	-1.8488832711188303	[10]	[4,2,1,0]	-9	hSpCas9	negative selection	7749929
89769908	89769931	8	+	27260156	PANC0327	viability	GTATCAAGCACGATATATATAGG	RIPK2	ENSG00000104312	0.39107375205442957	[623]	[1006,483,860,609]	6	hSpCas9	negative selection	7749930
89765400	89765423	8	-	27260156	PANC0327	viability	TGTGCAGGTAATTTACACCAAGG	RIPK2	ENSG00000104312	0.7373540056072833	[716]	[1543,884,866,1012]	9	hSpCas9	negative selection	7814182
89771737	89771760	8	+	27260156	PANC0327	viability	ACAGCTATGCAGTTATCACATGG	RIPK2	ENSG00000104312	0.11072310181866657	[487]	[457,547,440,413]	1	hSpCas9	negative selection	7814183
89769868	89769891	8	+	27260156	PANC0327	viability	CCACCTGAAAACTATGAACCTGG	RIPK2	ENSG00000104312	0.5208488928668661	[409]	[634,686,404,350]	7	hSpCas9	negative selection	7814184
89769905	89769928	8	-	27260156	NCIH2009	viability	ATATATATCGTGCTTGATACTGG	RIPK2	ENSG00000104312	-0.1787021122195921	[827]	[1060,755,1259]	-2	hSpCas9	negative selection	7871179
89765368	89765391	8	-	27260156	NCIH2009	viability	TGCAGGATGCGAAATCTCAATGG	RIPK2	ENSG00000104312	-0.06535492923082842	[10]	[8,9,23]	-1	hSpCas9	negative selection	7871180
89769908	89769931	8	+	27260156	NCIH2009	viability	GTATCAAGCACGATATATATAGG	RIPK2	ENSG00000104312	0.0997650569289909	[623]	[951,1025,824]	1	hSpCas9	negative selection	7871181
89765400	89765423	8	-	27260156	NCIH2009	viability	TGTGCAGGTAATTTACACCAAGG	RIPK2	ENSG00000104312	0.14071112471786318	[716]	[1289,827,1234]	2	hSpCas9	negative selection	7935433
89771737	89771760	8	+	27260156	NCIH2009	viability	ACAGCTATGCAGTTATCACATGG	RIPK2	ENSG00000104312	-0.17671762185802656	[487]	[557,694,544]	-2	hSpCas9	negative selection	7935434
89769868	89769891	8	+	27260156	NCIH2009	viability	CCACCTGAAAACTATGAACCTGG	RIPK2	ENSG00000104312	0.01669487585383414	[409]	[496,425,800]	0	hSpCas9	negative selection	7935435
89769905	89769928	8	-	27260156	NCIH1373	viability	ATATATATCGTGCTTGATACTGG	RIPK2	ENSG00000104312	-0.09432141785354586	[827]	[957,652,950,249]	-1	hSpCas9	negative selection	7992430
89765368	89765391	8	-	27260156	NCIH1373	viability	TGCAGGATGCGAAATCTCAATGG	RIPK2	ENSG00000104312	-0.8008014667942316	[10]	[13,5,1,1]	-7	hSpCas9	negative selection	7992431
89769908	89769931	8	+	27260156	NCIH1373	viability	GTATCAAGCACGATATATATAGG	RIPK2	ENSG00000104312	0.04460142381541893	[623]	[954,568,663,196]	0	hSpCas9	negative selection	7992432
89765400	89765423	8	-	27260156	NCIH1373	viability	TGTGCAGGTAATTTACACCAAGG	RIPK2	ENSG00000104312	1.533408108547	[716]	[8018,608,638,278]	9	hSpCas9	negative selection	8056684
89771737	89771760	8	+	27260156	NCIH1373	viability	ACAGCTATGCAGTTATCACATGG	RIPK2	ENSG00000104312	-0.302338759012982	[487]	[410,508,363,125]	-3	hSpCas9	negative selection	8056685
89769868	89769891	8	+	27260156	NCIH1373	viability	CCACCTGAAAACTATGAACCTGG	RIPK2	ENSG00000104312	0.6720853621381282	[409]	[1145,658,610,150]	6	hSpCas9	negative selection	8056686
89769905	89769928	8	-	27260156	PATU8902	viability	ATATATATCGTGCTTGATACTGG	RIPK2	ENSG00000104312	-0.5870289094359771	[827]	[818,1032,307,1058]	-5	hSpCas9	negative selection	8113681
89765368	89765391	8	-	27260156	PATU8902	viability	TGCAGGATGCGAAATCTCAATGG	RIPK2	ENSG00000104312	-3.934508834498917	[10]	[0,0,0,0]	-9	hSpCas9	negative selection	8113682
89769908	89769931	8	+	27260156	PATU8902	viability	GTATCAAGCACGATATATATAGG	RIPK2	ENSG00000104312	-0.6114024337072536	[623]	[738,751,304,537]	-5	hSpCas9	negative selection	8113683
89765400	89765423	8	-	27260156	PATU8902	viability	TGTGCAGGTAATTTACACCAAGG	RIPK2	ENSG00000104312	0.07952592985858586	[716]	[1151,985,777,1408]	0	hSpCas9	negative selection	8177935
89771737	89771760	8	+	27260156	PATU8902	viability	ACAGCTATGCAGTTATCACATGG	RIPK2	ENSG00000104312	-0.8143636607928096	[487]	[437,292,295,558]	-6	hSpCas9	negative selection	8177936
89769868	89769891	8	+	27260156	PATU8902	viability	CCACCTGAAAACTATGAACCTGG	RIPK2	ENSG00000104312	0.608087914707039	[409]	[822,586,524,1731]	6	hSpCas9	negative selection	8177937
89769905	89769928	8	-	27260156	PANC1	viability	ATATATATCGTGCTTGATACTGG	RIPK2	ENSG00000104312	-0.39149661576922434	[827]	[492,866,524,370]	-6	hSpCas9	negative selection	8234932
89765368	89765391	8	-	27260156	PANC1	viability	TGCAGGATGCGAAATCTCAATGG	RIPK2	ENSG00000104312	1.795245317299421	[10]	[5,69,50,14]	9	hSpCas9	negative selection	8234933
89769908	89769931	8	+	27260156	PANC1	viability	GTATCAAGCACGATATATATAGG	RIPK2	ENSG00000104312	0.18047955093312312	[623]	[480,580,610,723]	3	hSpCas9	negative selection	8234934
89765400	89765423	8	-	27260156	PANC1	viability	TGTGCAGGTAATTTACACCAAGG	RIPK2	ENSG00000104312	0.30185094569926985	[716]	[658,1002,744,681]	5	hSpCas9	negative selection	8299186
89771737	89771760	8	+	27260156	PANC1	viability	ACAGCTATGCAGTTATCACATGG	RIPK2	ENSG00000104312	-0.20011516370150612	[487]	[329,389,431,315]	-3	hSpCas9	negative selection	8299187
89769868	89769891	8	+	27260156	PANC1	viability	CCACCTGAAAACTATGAACCTGG	RIPK2	ENSG00000104312	-0.1633309211347669	[409]	[264,449,350,229]	-3	hSpCas9	negative selection	8299188
89769905	89769928	8	-	27260156	PANC0813	viability	ATATATATCGTGCTTGATACTGG	RIPK2	ENSG00000104312	-0.2622391620503699	[827]	[835,690,884,831]	-4	hSpCas9	negative selection	8356183
89765368	89765391	8	-	27260156	PANC0813	viability	TGCAGGATGCGAAATCTCAATGG	RIPK2	ENSG00000104312	1.5137130654427633	[10]	[4,48,76,14]	9	hSpCas9	negative selection	8356184
89769908	89769931	8	+	27260156	PANC0813	viability	GTATCAAGCACGATATATATAGG	RIPK2	ENSG00000104312	-0.39734024347739305	[623]	[515,555,445,694]	-6	hSpCas9	negative selection	8356185
89765400	89765423	8	-	27260156	PANC0813	viability	TGTGCAGGTAATTTACACCAAGG	RIPK2	ENSG00000104312	-0.1592807763679499	[716]	[931,930,581,594]	-3	hSpCas9	negative selection	8420437
89771737	89771760	8	+	27260156	PANC0813	viability	ACAGCTATGCAGTTATCACATGG	RIPK2	ENSG00000104312	-0.17702787746334536	[487]	[476,458,617,472]	-3	hSpCas9	negative selection	8420438
89769868	89769891	8	+	27260156	PANC0813	viability	CCACCTGAAAACTATGAACCTGG	RIPK2	ENSG00000104312	-0.15045702010546694	[409]	[625,391,367,369]	-2	hSpCas9	negative selection	8420439
89769905	89769928	8	-	27260156	RDES	viability	ATATATATCGTGCTTGATACTGG	RIPK2	ENSG00000104312	-0.4592640366589541	[827]	[452,757,654,971]	-7	hSpCas9	negative selection	8477434
89765368	89765391	8	-	27260156	RDES	viability	TGCAGGATGCGAAATCTCAATGG	RIPK2	ENSG00000104312	-0.2534832857153191	[10]	[14,14,7,0]	-4	hSpCas9	negative selection	8477435
89769908	89769931	8	+	27260156	RDES	viability	GTATCAAGCACGATATATATAGG	RIPK2	ENSG00000104312	-0.08850980784829837	[623]	[490,593,743,942]	-1	hSpCas9	negative selection	8477436
89765400	89765423	8	-	27260156	RDES	viability	TGTGCAGGTAATTTACACCAAGG	RIPK2	ENSG00000104312	0.20819035046249412	[716]	[777,916,999,1160]	3	hSpCas9	negative selection	8541688
89771737	89771760	8	+	27260156	RDES	viability	ACAGCTATGCAGTTATCACATGG	RIPK2	ENSG00000104312	-0.19339711202447943	[487]	[390,419,604,578]	-3	hSpCas9	negative selection	8541689
89769868	89769891	8	+	27260156	RDES	viability	CCACCTGAAAACTATGAACCTGG	RIPK2	ENSG00000104312	0.21512870617702337	[409]	[371,574,601,682]	3	hSpCas9	negative selection	8541690
89769905	89769928	8	-	27260156	PC3	viability	ATATATATCGTGCTTGATACTGG	RIPK2	ENSG00000104312	-0.5527422617904476	[827]	[367,497,923,636]	-8	hSpCas9	negative selection	8598685
89765368	89765391	8	-	27260156	PC3	viability	TGCAGGATGCGAAATCTCAATGG	RIPK2	ENSG00000104312	0.8462577335666825	[10]	[8,21,67,0]	9	hSpCas9	negative selection	8598686
89769908	89769931	8	+	27260156	PC3	viability	GTATCAAGCACGATATATATAGG	RIPK2	ENSG00000104312	-0.11492905961605632	[623]	[343,651,899,569]	-3	hSpCas9	negative selection	8598687
89765400	89765423	8	-	27260156	PC3	viability	TGTGCAGGTAATTTACACCAAGG	RIPK2	ENSG00000104312	0.04701172182637181	[716]	[565,659,1269,654]	1	hSpCas9	negative selection	8662939
89771737	89771760	8	+	27260156	PC3	viability	ACAGCTATGCAGTTATCACATGG	RIPK2	ENSG00000104312	-0.10122239105976691	[487]	[292,520,673,430]	-2	hSpCas9	negative selection	8662940
89769868	89769891	8	+	27260156	PC3	viability	CCACCTGAAAACTATGAACCTGG	RIPK2	ENSG00000104312	-0.007561586005342902	[409]	[327,314,762,346]	0	hSpCas9	negative selection	8662941
89769905	89769928	8	-	27260156	PATU8988T	viability	ATATATATCGTGCTTGATACTGG	RIPK2	ENSG00000104312	-0.19569440502105429	[827]	[687,931,684,494]	-3	hSpCas9	negative selection	8719936
89765368	89765391	8	-	27260156	PATU8988T	viability	TGCAGGATGCGAAATCTCAATGG	RIPK2	ENSG00000104312	0.46961681376067954	[10]	[5,9,29,11]	7	hSpCas9	negative selection	8719937
89769908	89769931	8	+	27260156	PATU8988T	viability	GTATCAAGCACGATATATATAGG	RIPK2	ENSG00000104312	0.15372080901874413	[623]	[512,753,571,868]	2	hSpCas9	negative selection	8719938
89765400	89765423	8	-	27260156	PATU8988T	viability	TGTGCAGGTAATTTACACCAAGG	RIPK2	ENSG00000104312	0.17462658523583652	[716]	[612,998,856,668]	3	hSpCas9	negative selection	8784190
89771737	89771760	8	+	27260156	PATU8988T	viability	ACAGCTATGCAGTTATCACATGG	RIPK2	ENSG00000104312	0.06616356952625466	[487]	[587,478,524,370]	1	hSpCas9	negative selection	8784191
89769868	89769891	8	+	27260156	PATU8988T	viability	CCACCTGAAAACTATGAACCTGG	RIPK2	ENSG00000104312	0.44443888962853173	[409]	[522,713,424,509]	7	hSpCas9	negative selection	8784192
89769905	89769928	8	-	27260156	T47D	viability	ATATATATCGTGCTTGATACTGG	RIPK2	ENSG00000104312	-0.38162143324002507	[827]	[691,674,776,824]	-7	hSpCas9	negative selection	8841187
89765368	89765391	8	-	27260156	T47D	viability	TGCAGGATGCGAAATCTCAATGG	RIPK2	ENSG00000104312	1.4494285351472245	[10]	[45,21,19,53]	9	hSpCas9	negative selection	8841188
89769908	89769931	8	+	27260156	T47D	viability	GTATCAAGCACGATATATATAGG	RIPK2	ENSG00000104312	-0.15182742124805415	[623]	[668,590,724,635]	-3	hSpCas9	negative selection	8841189
89765400	89765423	8	-	27260156	T47D	viability	TGTGCAGGTAATTTACACCAAGG	RIPK2	ENSG00000104312	0.28438711446893616	[716]	[1050,891,1083,1052]	6	hSpCas9	negative selection	8905441
89771737	89771760	8	+	27260156	T47D	viability	ACAGCTATGCAGTTATCACATGG	RIPK2	ENSG00000104312	-0.09608333045420986	[487]	[499,629,494,492]	-2	hSpCas9	negative selection	8905442
89769868	89769891	8	+	27260156	T47D	viability	CCACCTGAAAACTATGAACCTGG	RIPK2	ENSG00000104312	0.04159277471343953	[409]	[508,434,445,584]	0	hSpCas9	negative selection	8905443
89769905	89769928	8	-	27260156	SU8686	viability	ATATATATCGTGCTTGATACTGG	RIPK2	ENSG00000104312	-0.1176716196722547	[827]	[828,636,734,839]	-2	hSpCas9	negative selection	8962438
89765368	89765391	8	-	27260156	SU8686	viability	TGCAGGATGCGAAATCTCAATGG	RIPK2	ENSG00000104312	0.46516697400465556	[10]	[22,1,8,28]	7	hSpCas9	negative selection	8962439
89769908	89769931	8	+	27260156	SU8686	viability	GTATCAAGCACGATATATATAGG	RIPK2	ENSG00000104312	0.05384435533613968	[623]	[506,547,726,844]	0	hSpCas9	negative selection	8962440
89765400	89765423	8	-	27260156	SU8686	viability	TGTGCAGGTAATTTACACCAAGG	RIPK2	ENSG00000104312	0.09882879007259748	[716]	[680,691,841,860]	1	hSpCas9	negative selection	9026692
89771737	89771760	8	+	27260156	SU8686	viability	ACAGCTATGCAGTTATCACATGG	RIPK2	ENSG00000104312	-0.03740871076566259	[487]	[343,384,613,587]	0	hSpCas9	negative selection	9026693
89769868	89769891	8	+	27260156	SU8686	viability	CCACCTGAAAACTATGAACCTGG	RIPK2	ENSG00000104312	0.514056392532073	[409]	[627,457,672,569]	8	hSpCas9	negative selection	9026694
89769905	89769928	8	-	27260156	SKES1	viability	ATATATATCGTGCTTGATACTGG	RIPK2	ENSG00000104312	-0.34941410663975403	[827]	[802,661,493,651]	-6	hSpCas9	negative selection	9083689
89765368	89765391	8	-	27260156	SKES1	viability	TGCAGGATGCGAAATCTCAATGG	RIPK2	ENSG00000104312	0.6673283827964447	[10]	[22,0,3,37]	9	hSpCas9	negative selection	9083690
89769908	89769931	8	+	27260156	SKES1	viability	GTATCAAGCACGATATATATAGG	RIPK2	ENSG00000104312	-0.1736803538328048	[623]	[554,708,470,493]	-4	hSpCas9	negative selection	9083691
89765400	89765423	8	-	27260156	SKES1	viability	TGTGCAGGTAATTTACACCAAGG	RIPK2	ENSG00000104312	0.16860550700107435	[716]	[998,816,730,701]	3	hSpCas9	negative selection	9147943
89771737	89771760	8	+	27260156	SKES1	viability	ACAGCTATGCAGTTATCACATGG	RIPK2	ENSG00000104312	0.090283903474628	[487]	[809,620,384,328]	2	hSpCas9	negative selection	9147944
89769868	89769891	8	+	27260156	SKES1	viability	CCACCTGAAAACTATGAACCTGG	RIPK2	ENSG00000104312	0.29637302343863253	[409]	[650,531,458,398]	6	hSpCas9	negative selection	9147945
89769905	89769928	8	-	27260156	TOV112D	viability	ATATATATCGTGCTTGATACTGG	RIPK2	ENSG00000104312	-0.244781281744903	[827]	[511,1094,509,760]	-5	hSpCas9	negative selection	9204940
89765368	89765391	8	-	27260156	TOV112D	viability	TGCAGGATGCGAAATCTCAATGG	RIPK2	ENSG00000104312	-0.35517607314384314	[10]	[1,28,2,4]	-6	hSpCas9	negative selection	9204941
89769908	89769931	8	+	27260156	TOV112D	viability	GTATCAAGCACGATATATATAGG	RIPK2	ENSG00000104312	-0.1802854450339881	[623]	[343,882,476,564]	-4	hSpCas9	negative selection	9204942
89765400	89765423	8	-	27260156	TOV112D	viability	TGTGCAGGTAATTTACACCAAGG	RIPK2	ENSG00000104312	0.10452486111021941	[716]	[820,954,727,635]	2	hSpCas9	negative selection	9269194
89771737	89771760	8	+	27260156	TOV112D	viability	ACAGCTATGCAGTTATCACATGG	RIPK2	ENSG00000104312	-0.03406992641941228	[487]	[480,536,442,462]	0	hSpCas9	negative selection	9269195
89769868	89769891	8	+	27260156	TOV112D	viability	CCACCTGAAAACTATGAACCTGG	RIPK2	ENSG00000104312	0.4016374571872878	[409]	[424,543,415,767]	7	hSpCas9	negative selection	9269196
89769905	89769928	8	-	27260156	TC71	viability	ATATATATCGTGCTTGATACTGG	RIPK2	ENSG00000104312	-0.3371097109255467	[827]	[753,702,630,724]	-7	hSpCas9	negative selection	9326191
89765368	89765391	8	-	27260156	TC71	viability	TGCAGGATGCGAAATCTCAATGG	RIPK2	ENSG00000104312	0.8920633608639426	[10]	[16,8,19,42]	9	hSpCas9	negative selection	9326192
89769908	89769931	8	+	27260156	TC71	viability	GTATCAAGCACGATATATATAGG	RIPK2	ENSG00000104312	-0.06581998518274634	[623]	[663,566,605,724]	-2	hSpCas9	negative selection	9326193
89765400	89765423	8	-	27260156	TC71	viability	TGTGCAGGTAATTTACACCAAGG	RIPK2	ENSG00000104312	0.13254872248608318	[716]	[675,830,819,1060]	3	hSpCas9	negative selection	9390445
89771737	89771760	8	+	27260156	TC71	viability	ACAGCTATGCAGTTATCACATGG	RIPK2	ENSG00000104312	-0.0372545506069733	[487]	[413,555,584,481]	-1	hSpCas9	negative selection	9390446
89769868	89769891	8	+	27260156	TC71	viability	CCACCTGAAAACTATGAACCTGG	RIPK2	ENSG00000104312	0.06983969530473963	[409]	[520,492,368,463]	1	hSpCas9	negative selection	9390447
89769905	89769928	8	-	27260156	TC32	viability	ATATATATCGTGCTTGATACTGG	RIPK2	ENSG00000104312	-0.4291917936824348	[827]	[577,303,753,789]	-7	hSpCas9	negative selection	9447442
89765368	89765391	8	-	27260156	TC32	viability	TGCAGGATGCGAAATCTCAATGG	RIPK2	ENSG00000104312	-0.11196100066989345	[10]	[25,0,6,3]	-2	hSpCas9	negative selection	9447443
89769908	89769931	8	+	27260156	TC32	viability	GTATCAAGCACGATATATATAGG	RIPK2	ENSG00000104312	-0.5073572604531276	[623]	[502,232,464,494]	-7	hSpCas9	negative selection	9447444
89765400	89765423	8	-	27260156	TC32	viability	TGTGCAGGTAATTTACACCAAGG	RIPK2	ENSG00000104312	-0.19053875670443948	[716]	[445,555,712,666]	-3	hSpCas9	negative selection	9511696
89771737	89771760	8	+	27260156	TC32	viability	ACAGCTATGCAGTTATCACATGG	RIPK2	ENSG00000104312	-0.1128507074799437	[487]	[406,267,600,491]	-2	hSpCas9	negative selection	9511697
89769868	89769891	8	+	27260156	TC32	viability	CCACCTGAAAACTATGAACCTGG	RIPK2	ENSG00000104312	0.0471343521479462	[409]	[528,125,634,408]	0	hSpCas9	negative selection	9511698
89758047	89758070	8	+	27869803	HPAFII	viability after 27 days	GAGCGCCCGGGACCATGAACGGG	RIPK2	ENSG00000104312	-2.026717687318141	[321]	[46,36,NaN]	-8	hSpCas9	negative selection	9603369
89758095	89758118	8	-	27869803	HPAFII	viability after 27 days	GGCGAGTTTGTGGTAGGGAATGG	RIPK2	ENSG00000104312	0.4397670343685835	[307]	[253,190,NaN]	3	hSpCas9	negative selection	9603370
89758212	89758235	8	+	27869803	HPAFII	viability after 27 days	TCCACACTCCGCTGCTCGACAGG	RIPK2	ENSG00000104312	-0.3064687003193344	[240]	[108,96,NaN]	-2	hSpCas9	negative selection	9603371
89789387	89789410	8	-	27869803	HPAFII	viability after 27 days	AGCCCTTTGAGATCCAGAAATGG	RIPK2	ENSG00000104312	1.2189826824086307	[263]	[327,318,NaN]	8	hSpCas9	negative selection	9603372
89789458	89789481	8	-	27869803	HPAFII	viability after 27 days	GAGTTTCCTGCAGTTGAGAGTGG	RIPK2	ENSG00000104312	1.2081326214675268	[190]	[267,201,NaN]	8	hSpCas9	negative selection	9603373
89790179	89790202	8	-	27869803	HPAFII	viability after 27 days	TGATCAAGTCCCTGGACAGAAGG	RIPK2	ENSG00000104312	-1.5887654342710626	[348]	[30,85,NaN]	-7	hSpCas9	negative selection	9603374
89758047	89758070	8	+	27869803	HPAFII	viability after 15 days	GAGCGCCCGGGACCATGAACGGG	RIPK2	ENSG00000104312	-0.3209281666995479	[321]	[371,217,NaN]	-4	hSpCas9	negative selection	9685818
89758095	89758118	8	-	27869803	HPAFII	viability after 15 days	GGCGAGTTTGTGGTAGGGAATGG	RIPK2	ENSG00000104312	-0.09139223784876327	[307]	[462,215,NaN]	-1	hSpCas9	negative selection	9685819
89758212	89758235	8	+	27869803	HPAFII	viability after 15 days	TCCACACTCCGCTGCTCGACAGG	RIPK2	ENSG00000104312	-0.6668381272359105	[240]	[127,184,NaN]	-6	hSpCas9	negative selection	9685820
89789387	89789410	8	-	27869803	HPAFII	viability after 15 days	AGCCCTTTGAGATCCAGAAATGG	RIPK2	ENSG00000104312	0.6595155527356612	[263]	[597,354,NaN]	7	hSpCas9	negative selection	9685821
89789458	89789481	8	-	27869803	HPAFII	viability after 15 days	GAGTTTCCTGCAGTTGAGAGTGG	RIPK2	ENSG00000104312	0.5189973153434493	[190]	[451,195,NaN]	6	hSpCas9	negative selection	9685822
89790179	89790202	8	-	27869803	HPAFII	viability after 15 days	TGATCAAGTCCCTGGACAGAAGG	RIPK2	ENSG00000104312	-0.28482555113426694	[348]	[289,318,NaN]	-3	hSpCas9	negative selection	9685823
89758047	89758070	8	+	27869803	ASPC1	viability after 36 days	GAGCGCCCGGGACCATGAACGGG	RIPK2	ENSG00000104312	0.2194599814941052	[639]	[184,200,356]	2	hSpCas9	negative selection	9768267
89758095	89758118	8	-	27869803	ASPC1	viability after 36 days	GGCGAGTTTGTGGTAGGGAATGG	RIPK2	ENSG00000104312	-0.3976255897869861	[818]	[123,148,333]	-4	hSpCas9	negative selection	9768268
89758212	89758235	8	+	27869803	ASPC1	viability after 36 days	TCCACACTCCGCTGCTCGACAGG	RIPK2	ENSG00000104312	0.868294721136022	[610]	[854,248,169]	8	hSpCas9	negative selection	9768269
89789387	89789410	8	-	27869803	ASPC1	viability after 36 days	AGCCCTTTGAGATCCAGAAATGG	RIPK2	ENSG00000104312	0.3633193958700467	[742]	[494,359,195]	3	hSpCas9	negative selection	9768270
89789458	89789481	8	-	27869803	ASPC1	viability after 36 days	GAGTTTCCTGCAGTTGAGAGTGG	RIPK2	ENSG00000104312	0.20279554744807737	[616]	[220,174,321]	2	hSpCas9	negative selection	9768271
89790179	89790202	8	-	27869803	ASPC1	viability after 36 days	TGATCAAGTCCCTGGACAGAAGG	RIPK2	ENSG00000104312	0.3764386098483437	[669]	[315,204,369]	4	hSpCas9	negative selection	9768272
89758047	89758070	8	+	27869803	PATU8988S	viability after 35 days	GAGCGCCCGGGACCATGAACGGG	RIPK2	ENSG00000104312	0.5993224547288768	[521]	[321,314,NaN]	6	hSpCas9	negative selection	9850716
89758095	89758118	8	-	27869803	PATU8988S	viability after 35 days	GGCGAGTTTGTGGTAGGGAATGG	RIPK2	ENSG00000104312	-0.1517986889383779	[589]	[165,261,NaN]	-1	hSpCas9	negative selection	9850717
89758212	89758235	8	+	27869803	PATU8988S	viability after 35 days	TCCACACTCCGCTGCTCGACAGG	RIPK2	ENSG00000104312	-1.8639722274903157	[649]	[35,107,NaN]	-9	hSpCas9	negative selection	9850718
89789387	89789410	8	-	27869803	PATU8988S	viability after 35 days	AGCCCTTTGAGATCCAGAAATGG	RIPK2	ENSG00000104312	0.21272544621731151	[644]	[320,280,NaN]	2	hSpCas9	negative selection	9850719
89789458	89789481	8	-	27869803	PATU8988S	viability after 35 days	GAGTTTCCTGCAGTTGAGAGTGG	RIPK2	ENSG00000104312	1.153967962374174	[471]	[429,415,NaN]	9	hSpCas9	negative selection	9850720
89790179	89790202	8	-	27869803	PATU8988S	viability after 35 days	TGATCAAGTCCCTGGACAGAAGG	RIPK2	ENSG00000104312	0.46514346981936683	[509]	[304,261,NaN]	5	hSpCas9	negative selection	9850721
89758047	89758070	8	+	27869803	PATU8988S	viability after 31 days	GAGCGCCCGGGACCATGAACGGG	RIPK2	ENSG00000104312	0.18660029608649947	[521]	[257,209,NaN]	2	hSpCas9	negative selection	9933165
89758095	89758118	8	-	27869803	PATU8988S	viability after 31 days	GGCGAGTTTGTGGTAGGGAATGG	RIPK2	ENSG00000104312	-0.12512604064436258	[589]	[187,250,NaN]	-1	hSpCas9	negative selection	9933166
89758212	89758235	8	+	27869803	PATU8988S	viability after 31 days	TCCACACTCCGCTGCTCGACAGG	RIPK2	ENSG00000104312	-1.8464050940426453	[649]	[46,103,NaN]	-9	hSpCas9	negative selection	9933167
89789387	89789410	8	-	27869803	PATU8988S	viability after 31 days	AGCCCTTTGAGATCCAGAAATGG	RIPK2	ENSG00000104312	0.284855846251857	[644]	[366,244,NaN]	3	hSpCas9	negative selection	9933168
89789458	89789481	8	-	27869803	PATU8988S	viability after 31 days	GAGTTTCCTGCAGTTGAGAGTGG	RIPK2	ENSG00000104312	0.9774408122896676	[471]	[436,285,NaN]	9	hSpCas9	negative selection	9933169
89790179	89790202	8	-	27869803	PATU8988S	viability after 31 days	TGATCAAGTCCCTGGACAGAAGG	RIPK2	ENSG00000104312	0.1342893831605637	[509]	[209,239,NaN]	1	hSpCas9	negative selection	9933170
89758047	89758070	8	+	27869803	HPAFII	viability after 35 days	GAGCGCCCGGGACCATGAACGGG	RIPK2	ENSG00000104312	-1.2953906861437376	[321]	[72,58,NaN]	-6	hSpCas9	negative selection	10015614
89758095	89758118	8	-	27869803	HPAFII	viability after 35 days	GGCGAGTTTGTGGTAGGGAATGG	RIPK2	ENSG00000104312	0.3488285650369483	[307]	[286,98,NaN]	2	hSpCas9	negative selection	10015615
89758212	89758235	8	+	27869803	HPAFII	viability after 35 days	TCCACACTCCGCTGCTCGACAGG	RIPK2	ENSG00000104312	-0.42966378107211795	[240]	[75,106,NaN]	-3	hSpCas9	negative selection	10015616
89789387	89789410	8	-	27869803	HPAFII	viability after 35 days	AGCCCTTTGAGATCCAGAAATGG	RIPK2	ENSG00000104312	1.4172350831505205	[263]	[355,357,NaN]	8	hSpCas9	negative selection	10015617
89789458	89789481	8	-	27869803	HPAFII	viability after 35 days	GAGTTTCCTGCAGTTGAGAGTGG	RIPK2	ENSG00000104312	1.1231621430424872	[190]	[156,270,NaN]	7	hSpCas9	negative selection	10015618
89790179	89790202	8	-	27869803	HPAFII	viability after 35 days	TGATCAAGTCCCTGGACAGAAGG	RIPK2	ENSG00000104312	-1.0885131990577466	[348]	[12,161,NaN]	-6	hSpCas9	negative selection	10015619
89758047	89758070	8	+	27869803	HPAFII	viability after 31 days	GAGCGCCCGGGACCATGAACGGG	RIPK2	ENSG00000104312	-1.583459581426637	[321]	[66,52,NaN]	-7	hSpCas9	negative selection	10098063
89758095	89758118	8	-	27869803	HPAFII	viability after 31 days	GGCGAGTTTGTGGTAGGGAATGG	RIPK2	ENSG00000104312	0.4664594348147338	[307]	[357,108,NaN]	3	hSpCas9	negative selection	10098064
89758212	89758235	8	+	27869803	HPAFII	viability after 31 days	TCCACACTCCGCTGCTCGACAGG	RIPK2	ENSG00000104312	-0.25915679691395394	[240]	[90,136,NaN]	-2	hSpCas9	negative selection	10098065
89789387	89789410	8	-	27869803	HPAFII	viability after 31 days	AGCCCTTTGAGATCCAGAAATGG	RIPK2	ENSG00000104312	1.4037920732998763	[263]	[414,366,NaN]	9	hSpCas9	negative selection	10098066
89789458	89789481	8	-	27869803	HPAFII	viability after 31 days	GAGTTTCCTGCAGTTGAGAGTGG	RIPK2	ENSG00000104312	1.0588741066629277	[190]	[207,239,NaN]	7	hSpCas9	negative selection	10098067
89790179	89790202	8	-	27869803	HPAFII	viability after 31 days	TGATCAAGTCCCTGGACAGAAGG	RIPK2	ENSG00000104312	-0.6502379025595088	[348]	[30,226,NaN]	-4	hSpCas9	negative selection	10098068
89758051	89758074	8	+	28162770	P31FUJ	viability	GCCCGGGACCATGAACGGGGAGG	RIPK2	ENSG00000104312	-0.9983369507773552	[16]	[9]	-6	hSpCas9	negative selection	10225539
89765399	89765422	8	-	28162770	P31FUJ	viability	GTGCAGGTAATTTACACCAAGGG	RIPK2	ENSG00000104312	0.6713993036664998	[178]	[334]	7	hSpCas9	negative selection	10225540
89758118	89758141	8	+	28162770	P31FUJ	viability	GACCTGCGCTACCTGAGCCGCGG	RIPK2	ENSG00000104312	0.06293636649212081	[188]	[231]	0	hSpCas9	negative selection	10225541
89758074	89758097	8	-	28162770	P31FUJ	viability	GGTGGGCAGGGCGCTGCAGATGG	RIPK2	ENSG00000104312	-0.6126502752309224	[107]	[82]	-5	hSpCas9	negative selection	10225542
89758092	89758115	8	-	28162770	P31FUJ	viability	GAGTTTGTGGTAGGGAATGGTGG	RIPK2	ENSG00000104312	0.5358722494791657	[26]	[45]	6	hSpCas9	negative selection	10225543
89758165	89758188	8	-	28162770	P31FUJ	viability	GGACGCGCCAGTCTGCGTGGCGG	RIPK2	ENSG00000104312	0.4046277162009131	[134]	[209]	4	hSpCas9	negative selection	10225544
89769829	89769852	8	+	28162770	P31FUJ	viability	AGCAAATCTGCACCAGAAGGAGG	RIPK2	ENSG00000104312	0.7548669936749017	[234]	[465]	8	hSpCas9	negative selection	10225545
89758143	89758166	8	-	28162770	P31FUJ	viability	GGCGGACGACACAGTGCCAGAGG	RIPK2	ENSG00000104312	-0.11046666149032625	[112]	[122]	-1	hSpCas9	negative selection	10225546
89758204	89758227	8	-	28162770	P31FUJ	viability	GCAGCGGAGTGTGGATGTGCAGG	RIPK2	ENSG00000104312	0.229484666472758	[412]	[568]	2	hSpCas9	negative selection	10225547
89758220	89758243	8	-	28162770	P31FUJ	viability	ACTGCCTACCTGTCGAGCAGCGG	RIPK2	ENSG00000104312	-0.408244210824257	[130]	[115]	-4	hSpCas9	negative selection	10225548
89758051	89758074	8	+	28162770	TF1	viability	GCCCGGGACCATGAACGGGGAGG	RIPK2	ENSG00000104312	NaN	[NaN]	[0]	1	hSpCas9	negative selection	10394905
89765399	89765422	8	-	28162770	TF1	viability	GTGCAGGTAATTTACACCAAGGG	RIPK2	ENSG00000104312	NaN	[NaN]	[207]	1	hSpCas9	negative selection	10394906
89758118	89758141	8	+	28162770	TF1	viability	GACCTGCGCTACCTGAGCCGCGG	RIPK2	ENSG00000104312	NaN	[NaN]	[345]	1	hSpCas9	negative selection	10394907
89758074	89758097	8	-	28162770	TF1	viability	GGTGGGCAGGGCGCTGCAGATGG	RIPK2	ENSG00000104312	NaN	[NaN]	[68]	1	hSpCas9	negative selection	10394908
89758092	89758115	8	-	28162770	TF1	viability	GAGTTTGTGGTAGGGAATGGTGG	RIPK2	ENSG00000104312	NaN	[NaN]	[1]	1	hSpCas9	negative selection	10394909
89758165	89758188	8	-	28162770	TF1	viability	GGACGCGCCAGTCTGCGTGGCGG	RIPK2	ENSG00000104312	NaN	[NaN]	[49]	1	hSpCas9	negative selection	10394910
89769829	89769852	8	+	28162770	TF1	viability	AGCAAATCTGCACCAGAAGGAGG	RIPK2	ENSG00000104312	NaN	[NaN]	[255]	1	hSpCas9	negative selection	10394911
89758143	89758166	8	-	28162770	TF1	viability	GGCGGACGACACAGTGCCAGAGG	RIPK2	ENSG00000104312	NaN	[NaN]	[122]	1	hSpCas9	negative selection	10394912
89758204	89758227	8	-	28162770	TF1	viability	GCAGCGGAGTGTGGATGTGCAGG	RIPK2	ENSG00000104312	NaN	[NaN]	[367]	1	hSpCas9	negative selection	10394913
89758220	89758243	8	-	28162770	TF1	viability	ACTGCCTACCTGTCGAGCAGCGG	RIPK2	ENSG00000104312	NaN	[NaN]	[48]	1	hSpCas9	negative selection	10394914
89758051	89758074	8	+	28162770	SKM1	viability	GCCCGGGACCATGAACGGGGAGG	RIPK2	ENSG00000104312	1.5472321116437138	[5]	[30]	9	hSpCas9	negative selection	10564271
89765399	89765422	8	-	28162770	SKM1	viability	GTGCAGGTAATTTACACCAAGGG	RIPK2	ENSG00000104312	1.1121103663215375	[27]	[106]	8	hSpCas9	negative selection	10564272
89758118	89758141	8	+	28162770	SKM1	viability	GACCTGCGCTACCTGAGCCGCGG	RIPK2	ENSG00000104312	0.6429610265885208	[70]	[195]	6	hSpCas9	negative selection	10564273
89758074	89758097	8	-	28162770	SKM1	viability	GGTGGGCAGGGCGCTGCAGATGG	RIPK2	ENSG00000104312	-0.27451390271951226	[25]	[37]	-2	hSpCas9	negative selection	10564274
89758092	89758115	8	-	28162770	SKM1	viability	GAGTTTGTGGTAGGGAATGGTGG	RIPK2	ENSG00000104312	1.6273057033415843	[12]	[70]	9	hSpCas9	negative selection	10564275
89758165	89758188	8	-	28162770	SKM1	viability	GGACGCGCCAGTCTGCGTGGCGG	RIPK2	ENSG00000104312	-0.024818581021692473	[60]	[105]	0	hSpCas9	negative selection	10564276
89769829	89769852	8	+	28162770	SKM1	viability	AGCAAATCTGCACCAGAAGGAGG	RIPK2	ENSG00000104312	0.10506677952414328	[70]	[134]	1	hSpCas9	negative selection	10564277
89758143	89758166	8	-	28162770	SKM1	viability	GGCGGACGACACAGTGCCAGAGG	RIPK2	ENSG00000104312	0.3155018257279293	[29]	[65]	3	hSpCas9	negative selection	10564278
89758204	89758227	8	-	28162770	SKM1	viability	GCAGCGGAGTGTGGATGTGCAGG	RIPK2	ENSG00000104312	0.5133469126276783	[106]	[269]	5	hSpCas9	negative selection	10564279
89758220	89758243	8	-	28162770	SKM1	viability	ACTGCCTACCTGTCGAGCAGCGG	RIPK2	ENSG00000104312	0.4675049191729792	[17]	[43]	4	hSpCas9	negative selection	10564280
89758051	89758074	8	+	28162770	SKM1	viability	GCCCGGGACCATGAACGGGGAGG	RIPK2	ENSG00000104312	1.5472321116437138	[5]	[30]	9	hSpCas9	negative selection	10733637
89765399	89765422	8	-	28162770	SKM1	viability	GTGCAGGTAATTTACACCAAGGG	RIPK2	ENSG00000104312	1.1121103663215375	[27]	[106]	8	hSpCas9	negative selection	10733638
89758118	89758141	8	+	28162770	SKM1	viability	GACCTGCGCTACCTGAGCCGCGG	RIPK2	ENSG00000104312	0.6429610265885208	[70]	[195]	6	hSpCas9	negative selection	10733639
89758074	89758097	8	-	28162770	SKM1	viability	GGTGGGCAGGGCGCTGCAGATGG	RIPK2	ENSG00000104312	-0.27451390271951226	[25]	[37]	-2	hSpCas9	negative selection	10733640
89758092	89758115	8	-	28162770	SKM1	viability	GAGTTTGTGGTAGGGAATGGTGG	RIPK2	ENSG00000104312	1.6273057033415843	[12]	[70]	9	hSpCas9	negative selection	10733641
89758165	89758188	8	-	28162770	SKM1	viability	GGACGCGCCAGTCTGCGTGGCGG	RIPK2	ENSG00000104312	-0.024818581021692473	[60]	[105]	0	hSpCas9	negative selection	10733642
89769829	89769852	8	+	28162770	SKM1	viability	AGCAAATCTGCACCAGAAGGAGG	RIPK2	ENSG00000104312	0.10506677952414328	[70]	[134]	1	hSpCas9	negative selection	10733643
89758143	89758166	8	-	28162770	SKM1	viability	GGCGGACGACACAGTGCCAGAGG	RIPK2	ENSG00000104312	0.3155018257279293	[29]	[65]	3	hSpCas9	negative selection	10733644
89758204	89758227	8	-	28162770	SKM1	viability	GCAGCGGAGTGTGGATGTGCAGG	RIPK2	ENSG00000104312	0.5133469126276783	[106]	[269]	5	hSpCas9	negative selection	10733645
89758220	89758243	8	-	28162770	SKM1	viability	ACTGCCTACCTGTCGAGCAGCGG	RIPK2	ENSG00000104312	0.4675049191729792	[17]	[43]	4	hSpCas9	negative selection	10733646
89758051	89758074	8	+	28162770	PL21	viability	GCCCGGGACCATGAACGGGGAGG	RIPK2	ENSG00000104312	-1.0477878989542657	[18]	[3]	-6	hSpCas9	negative selection	10903003
89765399	89765422	8	-	28162770	PL21	viability	GTGCAGGTAATTTACACCAAGGG	RIPK2	ENSG00000104312	0.6282332665936101	[109]	[73]	5	hSpCas9	negative selection	10903004
89758118	89758141	8	+	28162770	PL21	viability	GACCTGCGCTACCTGAGCCGCGG	RIPK2	ENSG00000104312	-0.18420108756660714	[247]	[94]	-1	hSpCas9	negative selection	10903005
89758074	89758097	8	-	28162770	PL21	viability	GGTGGGCAGGGCGCTGCAGATGG	RIPK2	ENSG00000104312	-1.500300103651772	[90]	[13]	-7	hSpCas9	negative selection	10903006
89758092	89758115	8	-	28162770	PL21	viability	GAGTTTGTGGTAGGGAATGGTGG	RIPK2	ENSG00000104312	-0.2669863959379777	[46]	[16]	-2	hSpCas9	negative selection	10903007
89758165	89758188	8	-	28162770	PL21	viability	GGACGCGCCAGTCTGCGTGGCGG	RIPK2	ENSG00000104312	0.3980789921012292	[135]	[77]	3	hSpCas9	negative selection	10903008
89769829	89769852	8	+	28162770	PL21	viability	AGCAAATCTGCACCAGAAGGAGG	RIPK2	ENSG00000104312	-0.4157168941776197	[235]	[76]	-3	hSpCas9	negative selection	10903009
89758143	89758166	8	-	28162770	PL21	viability	GGCGGACGACACAGTGCCAGAGG	RIPK2	ENSG00000104312	-0.18233002233309326	[72]	[27]	-1	hSpCas9	negative selection	10903010
89758204	89758227	8	-	28162770	PL21	viability	GCAGCGGAGTGTGGATGTGCAGG	RIPK2	ENSG00000104312	0.5950695403195893	[288]	[189]	5	hSpCas9	negative selection	10903011
89758220	89758243	8	-	28162770	PL21	viability	ACTGCCTACCTGTCGAGCAGCGG	RIPK2	ENSG00000104312	0.9640722562557958	[52]	[44]	7	hSpCas9	negative selection	10903012
89758051	89758074	8	+	28162770	P31FUJ	viability	GCCCGGGACCATGAACGGGGAGG	RIPK2	ENSG00000104312	-0.9983369507773552	[16]	[9]	-6	hSpCas9	negative selection	11072369
89765399	89765422	8	-	28162770	P31FUJ	viability	GTGCAGGTAATTTACACCAAGGG	RIPK2	ENSG00000104312	0.6713993036664998	[178]	[334]	7	hSpCas9	negative selection	11072370
89758118	89758141	8	+	28162770	P31FUJ	viability	GACCTGCGCTACCTGAGCCGCGG	RIPK2	ENSG00000104312	0.06293636649212081	[188]	[231]	0	hSpCas9	negative selection	11072371
89758074	89758097	8	-	28162770	P31FUJ	viability	GGTGGGCAGGGCGCTGCAGATGG	RIPK2	ENSG00000104312	-0.6126502752309224	[107]	[82]	-5	hSpCas9	negative selection	11072372
89758092	89758115	8	-	28162770	P31FUJ	viability	GAGTTTGTGGTAGGGAATGGTGG	RIPK2	ENSG00000104312	0.5358722494791657	[26]	[45]	6	hSpCas9	negative selection	11072373
89758165	89758188	8	-	28162770	P31FUJ	viability	GGACGCGCCAGTCTGCGTGGCGG	RIPK2	ENSG00000104312	0.4046277162009131	[134]	[209]	4	hSpCas9	negative selection	11072374
89769829	89769852	8	+	28162770	P31FUJ	viability	AGCAAATCTGCACCAGAAGGAGG	RIPK2	ENSG00000104312	0.7548669936749017	[234]	[465]	8	hSpCas9	negative selection	11072375
89758143	89758166	8	-	28162770	P31FUJ	viability	GGCGGACGACACAGTGCCAGAGG	RIPK2	ENSG00000104312	-0.11046666149032625	[112]	[122]	-1	hSpCas9	negative selection	11072376
89758204	89758227	8	-	28162770	P31FUJ	viability	GCAGCGGAGTGTGGATGTGCAGG	RIPK2	ENSG00000104312	0.229484666472758	[412]	[568]	2	hSpCas9	negative selection	11072377
89758220	89758243	8	-	28162770	P31FUJ	viability	ACTGCCTACCTGTCGAGCAGCGG	RIPK2	ENSG00000104312	-0.408244210824257	[130]	[115]	-4	hSpCas9	negative selection	11072378
89758051	89758074	8	+	28162770	OCIAML5	viability	GCCCGGGACCATGAACGGGGAGG	RIPK2	ENSG00000104312	2.125213352635919	[7]	[62]	9	hSpCas9	negative selection	11241735
89765399	89765422	8	-	28162770	OCIAML5	viability	GTGCAGGTAATTTACACCAAGGG	RIPK2	ENSG00000104312	-0.35326071389255526	[91]	[129]	-3	hSpCas9	negative selection	11241736
89758118	89758141	8	+	28162770	OCIAML5	viability	GACCTGCGCTACCTGAGCCGCGG	RIPK2	ENSG00000104312	0.15758359916972225	[148]	[299]	1	hSpCas9	negative selection	11241737
89758074	89758097	8	-	28162770	OCIAML5	viability	GGTGGGCAGGGCGCTGCAGATGG	RIPK2	ENSG00000104312	-2.2082103810892724	[63]	[24]	-8	hSpCas9	negative selection	11241738
89758092	89758115	8	-	28162770	OCIAML5	viability	GAGTTTGTGGTAGGGAATGGTGG	RIPK2	ENSG00000104312	2.218322757027401	[9]	[83]	9	hSpCas9	negative selection	11241739
89758165	89758188	8	-	28162770	OCIAML5	viability	GGACGCGCCAGTCTGCGTGGCGG	RIPK2	ENSG00000104312	1.0661902796944664	[58]	[222]	8	hSpCas9	negative selection	11241740
89769829	89769852	8	+	28162770	OCIAML5	viability	AGCAAATCTGCACCAGAAGGAGG	RIPK2	ENSG00000104312	0.4285404644177466	[169]	[412]	3	hSpCas9	negative selection	11241741
89758143	89758166	8	-	28162770	OCIAML5	viability	GGCGGACGACACAGTGCCAGAGG	RIPK2	ENSG00000104312	0.8177848274436723	[32]	[104]	7	hSpCas9	negative selection	11241742
89758204	89758227	8	-	28162770	OCIAML5	viability	GCAGCGGAGTGTGGATGTGCAGG	RIPK2	ENSG00000104312	0.23199769392447755	[149]	[317]	2	hSpCas9	negative selection	11241743
89758220	89758243	8	-	28162770	OCIAML5	viability	ACTGCCTACCTGTCGAGCAGCGG	RIPK2	ENSG00000104312	-0.9242163566198325	[40]	[38]	-5	hSpCas9	negative selection	11241744
89758051	89758074	8	+	28162770	EOL1	viability	GCCCGGGACCATGAACGGGGAGG	RIPK2	ENSG00000104312	-2.1909294458494015	[51]	[5]	-8	hSpCas9	negative selection	11411101
89765399	89765422	8	-	28162770	EOL1	viability	GTGCAGGTAATTTACACCAAGGG	RIPK2	ENSG00000104312	-0.04630588276994896	[146]	[74]	0	hSpCas9	negative selection	11411102
89758118	89758141	8	+	28162770	EOL1	viability	GACCTGCGCTACCTGAGCCGCGG	RIPK2	ENSG00000104312	0.27027217951731963	[468]	[297]	2	hSpCas9	negative selection	11411103
89758074	89758097	8	-	28162770	EOL1	viability	GGTGGGCAGGGCGCTGCAGATGG	RIPK2	ENSG00000104312	-0.9929900682374924	[169]	[44]	-6	hSpCas9	negative selection	11411104
89758092	89758115	8	-	28162770	EOL1	viability	GAGTTTGTGGTAGGGAATGGTGG	RIPK2	ENSG00000104312	2.133134393381952	[44]	[103]	9	hSpCas9	negative selection	11411105
89758165	89758188	8	-	28162770	EOL1	viability	GGACGCGCCAGTCTGCGTGGCGG	RIPK2	ENSG00000104312	0.1469401929069825	[275]	[160]	1	hSpCas9	negative selection	11411106
89769829	89769852	8	+	28162770	EOL1	viability	AGCAAATCTGCACCAGAAGGAGG	RIPK2	ENSG00000104312	0.10022744773865416	[277]	[156]	0	hSpCas9	negative selection	11411107
89758143	89758166	8	-	28162770	EOL1	viability	GGCGGACGACACAGTGCCAGAGG	RIPK2	ENSG00000104312	-0.0014516469856886705	[132]	[69]	0	hSpCas9	negative selection	11411108
89758204	89758227	8	-	28162770	EOL1	viability	GCAGCGGAGTGTGGATGTGCAGG	RIPK2	ENSG00000104312	-0.23519585352354266	[352]	[157]	-2	hSpCas9	negative selection	11411109
89758220	89758243	8	-	28162770	EOL1	viability	ACTGCCTACCTGTCGAGCAGCGG	RIPK2	ENSG00000104312	0.44750061001626595	[102]	[73]	4	hSpCas9	negative selection	11411110
89758051	89758074	8	+	28162770	MOLM13	viability	GCCCGGGACCATGAACGGGGAGG	RIPK2	ENSG00000104312	0.9373746648457986	[12]	[17]	7	hSpCas9	negative selection	11580467
89765399	89765422	8	-	28162770	MOLM13	viability	GTGCAGGTAATTTACACCAAGGG	RIPK2	ENSG00000104312	1.1737766645253414	[121]	[198]	8	hSpCas9	negative selection	11580468
89758118	89758141	8	+	28162770	MOLM13	viability	GACCTGCGCTACCTGAGCCGCGG	RIPK2	ENSG00000104312	0.0024783597506156073	[271]	[196]	0	hSpCas9	negative selection	11580469
89758074	89758097	8	-	28162770	MOLM13	viability	GGTGGGCAGGGCGCTGCAGATGG	RIPK2	ENSG00000104312	-1.6336486449174834	[102]	[23]	-7	hSpCas9	negative selection	11580470
89758092	89758115	8	-	28162770	MOLM13	viability	GAGTTTGTGGTAGGGAATGGTGG	RIPK2	ENSG00000104312	0.08086625843533124	[16]	[12]	0	hSpCas9	negative selection	11580471
89758165	89758188	8	-	28162770	MOLM13	viability	GGACGCGCCAGTCTGCGTGGCGG	RIPK2	ENSG00000104312	-3.2988235560156793	[244]	[17]	-8	hSpCas9	negative selection	11580472
89769829	89769852	8	+	28162770	MOLM13	viability	AGCAAATCTGCACCAGAAGGAGG	RIPK2	ENSG00000104312	-0.1253407351601777	[349]	[231]	-1	hSpCas9	negative selection	11580473
89758143	89758166	8	-	28162770	MOLM13	viability	GGCGGACGACACAGTGCCAGAGG	RIPK2	ENSG00000104312	-0.6357332495295789	[100]	[46]	-4	hSpCas9	negative selection	11580474
89758204	89758227	8	-	28162770	MOLM13	viability	GCAGCGGAGTGTGGATGTGCAGG	RIPK2	ENSG00000104312	0.9992509987906544	[392]	[567]	7	hSpCas9	negative selection	11580475
89758220	89758243	8	-	28162770	MOLM13	viability	ACTGCCTACCTGTCGAGCAGCGG	RIPK2	ENSG00000104312	-0.6039013015234311	[102]	[48]	-3	hSpCas9	negative selection	11580476
89758051	89758074	8	+	28162770	HEL	viability	GCCCGGGACCATGAACGGGGAGG	RIPK2	ENSG00000104312	1.0788379468070302	[16]	[22]	8	hSpCas9	negative selection	11749833
89765399	89765422	8	-	28162770	HEL	viability	GTGCAGGTAATTTACACCAAGGG	RIPK2	ENSG00000104312	0.5802747450537034	[117]	[112]	5	hSpCas9	negative selection	11749834
89758118	89758141	8	+	28162770	HEL	viability	GACCTGCGCTACCTGAGCCGCGG	RIPK2	ENSG00000104312	0.5613712811483673	[309]	[292]	5	hSpCas9	negative selection	11749835
89758074	89758097	8	-	28162770	HEL	viability	GGTGGGCAGGGCGCTGCAGATGG	RIPK2	ENSG00000104312	0.3607034642365071	[106]	[87]	3	hSpCas9	negative selection	11749836
89758092	89758115	8	-	28162770	HEL	viability	GAGTTTGTGGTAGGGAATGGTGG	RIPK2	ENSG00000104312	0.22770133272151316	[31]	[23]	1	hSpCas9	negative selection	11749837
89758165	89758188	8	-	28162770	HEL	viability	GGACGCGCCAGTCTGCGTGGCGG	RIPK2	ENSG00000104312	0.43328546637140714	[184]	[159]	3	hSpCas9	negative selection	11749838
89769829	89769852	8	+	28162770	HEL	viability	AGCAAATCTGCACCAGAAGGAGG	RIPK2	ENSG00000104312	0.379704426166563	[287]	[239]	3	hSpCas9	negative selection	11749839
89758143	89758166	8	-	28162770	HEL	viability	GGCGGACGACACAGTGCCAGAGG	RIPK2	ENSG00000104312	-2.6791892628870055	[99]	[9]	-8	hSpCas9	negative selection	11749840
89758204	89758227	8	-	28162770	HEL	viability	GCAGCGGAGTGTGGATGTGCAGG	RIPK2	ENSG00000104312	0.39420399586167815	[296]	[249]	3	hSpCas9	negative selection	11749841
89758220	89758243	8	-	28162770	HEL	viability	ACTGCCTACCTGTCGAGCAGCGG	RIPK2	ENSG00000104312	-0.4045668827779998	[61]	[29]	-3	hSpCas9	negative selection	11749842
89758051	89758074	8	+	28162770	MV411	viability	GCCCGGGACCATGAACGGGGAGG	RIPK2	ENSG00000104312	-0.19068356160910938	[41]	[30]	-1	hSpCas9	negative selection	11919199
89765399	89765422	8	-	28162770	MV411	viability	GTGCAGGTAATTTACACCAAGGG	RIPK2	ENSG00000104312	0.672459138634241	[107]	[144]	6	hSpCas9	negative selection	11919200
89758118	89758141	8	+	28162770	MV411	viability	GACCTGCGCTACCTGAGCCGCGG	RIPK2	ENSG00000104312	-0.675157945531618	[253]	[133]	-5	hSpCas9	negative selection	11919201
89758074	89758097	8	-	28162770	MV411	viability	GGTGGGCAGGGCGCTGCAGATGG	RIPK2	ENSG00000104312	-0.4783874857782304	[85]	[51]	-4	hSpCas9	negative selection	11919202
89758092	89758115	8	-	28162770	MV411	viability	GAGTTTGTGGTAGGGAATGGTGG	RIPK2	ENSG00000104312	1.0494981731708661	[38]	[67]	8	hSpCas9	negative selection	11919203
89758165	89758188	8	-	28162770	MV411	viability	GGACGCGCCAGTCTGCGTGGCGG	RIPK2	ENSG00000104312	-0.017704518013009707	[136]	[113]	0	hSpCas9	negative selection	11919204
89769829	89769852	8	+	28162770	MV411	viability	AGCAAATCTGCACCAGAAGGAGG	RIPK2	ENSG00000104312	0.5828980589769883	[190]	[240]	5	hSpCas9	negative selection	11919205
89758143	89758166	8	-	28162770	MV411	viability	GGCGGACGACACAGTGCCAGAGG	RIPK2	ENSG00000104312	0.9478772689238673	[55]	[90]	8	hSpCas9	negative selection	11919206
89758204	89758227	8	-	28162770	MV411	viability	GCAGCGGAGTGTGGATGTGCAGG	RIPK2	ENSG00000104312	0.7051795010158572	[232]	[319]	6	hSpCas9	negative selection	11919207
89758220	89758243	8	-	28162770	MV411	viability	ACTGCCTACCTGTCGAGCAGCGG	RIPK2	ENSG00000104312	-0.2798094520820936	[97]	[67]	-2	hSpCas9	negative selection	11919208
89758051	89758074	8	+	28162770	MONOMAC1	viability	GCCCGGGACCATGAACGGGGAGG	RIPK2	ENSG00000104312	-0.05953332330961869	[9]	[10]	0	hSpCas9	negative selection	12088565
89765399	89765422	8	-	28162770	MONOMAC1	viability	GTGCAGGTAATTTACACCAAGGG	RIPK2	ENSG00000104312	-0.6750841438641978	[77]	[55]	-5	hSpCas9	negative selection	12088566
89758118	89758141	8	+	28162770	MONOMAC1	viability	GACCTGCGCTACCTGAGCCGCGG	RIPK2	ENSG00000104312	-0.03384667964596916	[166]	[186]	0	hSpCas9	negative selection	12088567
89758074	89758097	8	-	28162770	MONOMAC1	viability	GGTGGGCAGGGCGCTGCAGATGG	RIPK2	ENSG00000104312	0.10064370158113123	[47]	[58]	1	hSpCas9	negative selection	12088568
89758092	89758115	8	-	28162770	MONOMAC1	viability	GAGTTTGTGGTAGGGAATGGTGG	RIPK2	ENSG00000104312	1.7289625714966697	[9]	[37]	9	hSpCas9	negative selection	12088569
89758165	89758188	8	-	28162770	MONOMAC1	viability	GGACGCGCCAGTCTGCGTGGCGG	RIPK2	ENSG00000104312	0.05153950608054926	[116]	[138]	0	hSpCas9	negative selection	12088570
89769829	89769852	8	+	28162770	MONOMAC1	viability	AGCAAATCTGCACCAGAAGGAGG	RIPK2	ENSG00000104312	-0.4068292316163681	[132]	[114]	-4	hSpCas9	negative selection	12088571
89758143	89758166	8	-	28162770	MONOMAC1	viability	GGCGGACGACACAGTGCCAGAGG	RIPK2	ENSG00000104312	-0.22618319271907006	[49]	[48]	-2	hSpCas9	negative selection	12088572
89758204	89758227	8	-	28162770	MONOMAC1	viability	GCAGCGGAGTGTGGATGTGCAGG	RIPK2	ENSG00000104312	0.6729026123760735	[173]	[317]	6	hSpCas9	negative selection	12088573
89758220	89758243	8	-	28162770	MONOMAC1	viability	ACTGCCTACCTGTCGAGCAGCGG	RIPK2	ENSG00000104312	-0.7984874705692788	[43]	[28]	-6	hSpCas9	negative selection	12088574
89758051	89758074	8	+	28162770	OCIAML2	viability	GCCCGGGACCATGAACGGGGAGG	RIPK2	ENSG00000104312	-0.3831669839918219	[7]	[33]	-3	hSpCas9	negative selection	12257931
89765399	89765422	8	-	28162770	OCIAML2	viability	GTGCAGGTAATTTACACCAAGGG	RIPK2	ENSG00000104312	1.4753303350449496	[16]	[261]	9	hSpCas9	negative selection	12257932
89758118	89758141	8	+	28162770	OCIAML2	viability	GACCTGCGCTACCTGAGCCGCGG	RIPK2	ENSG00000104312	0.36890550256459287	[56]	[407]	3	hSpCas9	negative selection	12257933
89758074	89758097	8	-	28162770	OCIAML2	viability	GGTGGGCAGGGCGCTGCAGATGG	RIPK2	ENSG00000104312	0.09705468404715911	[13]	[82]	0	hSpCas9	negative selection	12257934
89758092	89758115	8	-	28162770	OCIAML2	viability	GAGTTTGTGGTAGGGAATGGTGG	RIPK2	ENSG00000104312	-0.8856673245210049	[7]	[23]	-6	hSpCas9	negative selection	12257935
89758165	89758188	8	-	28162770	OCIAML2	viability	GGACGCGCCAGTCTGCGTGGCGG	RIPK2	ENSG00000104312	0.9782711259029666	[24]	[272]	8	hSpCas9	negative selection	12257936
89769829	89769852	8	+	28162770	OCIAML2	viability	AGCAAATCTGCACCAGAAGGAGG	RIPK2	ENSG00000104312	-0.03891358481668716	[42]	[231]	0	hSpCas9	negative selection	12257937
89758143	89758166	8	-	28162770	OCIAML2	viability	GGCGGACGACACAGTGCCAGAGG	RIPK2	ENSG00000104312	-1.0300572338561795	[20]	[56]	-6	hSpCas9	negative selection	12257938
89758204	89758227	8	-	28162770	OCIAML2	viability	GCAGCGGAGTGTGGATGTGCAGG	RIPK2	ENSG00000104312	0.03489820798458998	[55]	[317]	0	hSpCas9	negative selection	12257939
89758220	89758243	8	-	28162770	OCIAML2	viability	ACTGCCTACCTGTCGAGCAGCGG	RIPK2	ENSG00000104312	0.51288205196927	[21]	[173]	5	hSpCas9	negative selection	12257940
89758051	89758074	8	+	28162770	OCIAML3	viability	GCCCGGGACCATGAACGGGGAGG	RIPK2	ENSG00000104312	0.34459181501169356	[5]	[22]	3	hSpCas9	negative selection	12427297
89765399	89765422	8	-	28162770	OCIAML3	viability	GTGCAGGTAATTTACACCAAGGG	RIPK2	ENSG00000104312	-0.0485735037896442	[36]	[107]	0	hSpCas9	negative selection	12427298
89758118	89758141	8	+	28162770	OCIAML3	viability	GACCTGCGCTACCTGAGCCGCGG	RIPK2	ENSG00000104312	0.631412473709853	[67]	[317]	6	hSpCas9	negative selection	12427299
89758074	89758097	8	-	28162770	OCIAML3	viability	GGTGGGCAGGGCGCTGCAGATGG	RIPK2	ENSG00000104312	0.05170889147608926	[30]	[96]	0	hSpCas9	negative selection	12427300
89758092	89758115	8	-	28162770	OCIAML3	viability	GAGTTTGTGGTAGGGAATGGTGG	RIPK2	ENSG00000104312	-1.2720795454368008	[3]	[4]	-7	hSpCas9	negative selection	12427301
89758165	89758188	8	-	28162770	OCIAML3	viability	GGACGCGCCAGTCTGCGTGGCGG	RIPK2	ENSG00000104312	0.9778987075715468	[36]	[219]	8	hSpCas9	negative selection	12427302
89769829	89769852	8	+	28162770	OCIAML3	viability	AGCAAATCTGCACCAGAAGGAGG	RIPK2	ENSG00000104312	-0.2003437918378863	[50]	[133]	-1	hSpCas9	negative selection	12427303
89758143	89758166	8	-	28162770	OCIAML3	viability	GGCGGACGACACAGTGCCAGAGG	RIPK2	ENSG00000104312	0.05580600474696096	[28]	[90]	0	hSpCas9	negative selection	12427304
89758204	89758227	8	-	28162770	OCIAML3	viability	GCAGCGGAGTGTGGATGTGCAGG	RIPK2	ENSG00000104312	1.077815700786985	[93]	[598]	8	hSpCas9	negative selection	12427305
89758220	89758243	8	-	28162770	OCIAML3	viability	ACTGCCTACCTGTCGAGCAGCGG	RIPK2	ENSG00000104312	-1.50911874273765	[32]	[34]	-8	hSpCas9	negative selection	12427306