Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:6041
• Symbol:RNASEL
• Description:ribonuclease L

DataSource: http://genomecrispr.dkfz.de/#!/results/RNASEL

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
182586302	182586325	1	-	26472758	Jiyoye	viability	AGAGCGGCTGAGGAAAGGAGGGG	RNASEL	ENSG00000135828	-0.21797620933098177	[90]	[58]	-1	hSpCas9	negative selection	137715
182585617	182585640	1	-	26472758	Jiyoye	viability	GCTGTGAAGACGTTCTGTGAGGG	RNASEL	ENSG00000135828	0.6891513509931274	[226]	[275]	5	hSpCas9	negative selection	137716
182585846	182585869	1	+	26472758	Jiyoye	viability	GAAGAACCTTCACAAGGGAATGG	RNASEL	ENSG00000135828	0.4071753815058732	[346]	[346]	3	hSpCas9	negative selection	137717
182585723	182585746	1	+	26472758	Jiyoye	viability	TGAGTTTGCCAATCATAGGGCGG	RNASEL	ENSG00000135828	0.7705234037732166	[205]	[264]	5	hSpCas9	negative selection	137718
182585598	182585621	1	-	26472758	Jiyoye	viability	AGGGCAGCCCACGTGCACAGCGG	RNASEL	ENSG00000135828	1.3944643297563193	[56]	[112]	8	hSpCas9	negative selection	137719
182586754	182586777	1	-	26472758	Jiyoye	viability	GAGGGACCCACGTCCTCCAGCGG	RNASEL	ENSG00000135828	-0.4385778309096152	[256]	[142]	-3	hSpCas9	negative selection	137720
182586329	182586352	1	-	26472758	Jiyoye	viability	TTTGAGGCGAAAGACAAAGGAGG	RNASEL	ENSG00000135828	-2.914752713381489	[129]	[12]	-9	hSpCas9	negative selection	137721
182586233	182586256	1	-	26472758	Jiyoye	viability	GAAGATTCTCCTTGATGAGATGG	RNASEL	ENSG00000135828	-1.7910942456304004	[256]	[55]	-8	hSpCas9	negative selection	137722
182585776	182585799	1	-	26472758	Jiyoye	viability	AAGCCTCAGAGCTCACACTGGGG	RNASEL	ENSG00000135828	0.0323269723427284	[117]	[90]	0	hSpCas9	negative selection	137723
182585661	182585684	1	-	26472758	Jiyoye	viability	CAGAAGGAGGCATCTACCTGGGG	RNASEL	ENSG00000135828	-0.6326256265521014	[293]	[142]	-4	hSpCas9	negative selection	137724
182586302	182586325	1	-	26472758	KBM7	viability	AGAGCGGCTGAGGAAAGGAGGGG	RNASEL	ENSG00000135828	0.43411296204744226	[280,337]	[266,138]	5	hSpCas9	negative selection	328833
182585617	182585640	1	-	26472758	KBM7	viability	GCTGTGAAGACGTTCTGTGAGGG	RNASEL	ENSG00000135828	0.44787960791621906	[1383,1624]	[1033,926]	5	hSpCas9	negative selection	328834
182585846	182585869	1	+	26472758	KBM7	viability	GAAGAACCTTCACAAGGGAATGG	RNASEL	ENSG00000135828	0.2064219435574568	[1097,846]	[679,382]	2	hSpCas9	negative selection	328835
182585723	182585746	1	+	26472758	KBM7	viability	TGAGTTTGCCAATCATAGGGCGG	RNASEL	ENSG00000135828	-0.0487188390084925	[1572,1060]	[623,558]	0	hSpCas9	negative selection	328836
182585598	182585621	1	-	26472758	KBM7	viability	AGGGCAGCCCACGTGCACAGCGG	RNASEL	ENSG00000135828	1.0091404178293601	[400,311]	[377,295]	9	hSpCas9	negative selection	328837
182586754	182586777	1	-	26472758	KBM7	viability	GAGGGACCCACGTCCTCCAGCGG	RNASEL	ENSG00000135828	0.46608578270605716	[728,723]	[511,439]	5	hSpCas9	negative selection	328838
182586329	182586352	1	-	26472758	KBM7	viability	TTTGAGGCGAAAGACAAAGGAGG	RNASEL	ENSG00000135828	-0.5538101175771606	[181,199]	[84,40]	-5	hSpCas9	negative selection	328839
182586233	182586256	1	-	26472758	KBM7	viability	GAAGATTCTCCTTGATGAGATGG	RNASEL	ENSG00000135828	-0.24532817509586846	[719,443]	[171,274]	-2	hSpCas9	negative selection	328840
182585776	182585799	1	-	26472758	KBM7	viability	AAGCCTCAGAGCTCACACTGGGG	RNASEL	ENSG00000135828	0.002809524801444252	[364,377]	[219,136]	0	hSpCas9	negative selection	328841
182585661	182585684	1	-	26472758	KBM7	viability	CAGAAGGAGGCATCTACCTGGGG	RNASEL	ENSG00000135828	0.5677314863325882	[893,939]	[552,724]	6	hSpCas9	negative selection	328842
182586302	182586325	1	-	26472758	Raji	viability	AGAGCGGCTGAGGAAAGGAGGGG	RNASEL	ENSG00000135828	-0.5771146388984711	[134]	[20]	-4	hSpCas9	negative selection	519951
182585617	182585640	1	-	26472758	Raji	viability	GCTGTGAAGACGTTCTGTGAGGG	RNASEL	ENSG00000135828	0.34277826077533224	[930]	[273]	3	hSpCas9	negative selection	519952
182585846	182585869	1	+	26472758	Raji	viability	GAAGAACCTTCACAAGGGAATGG	RNASEL	ENSG00000135828	-0.5566072115128273	[468]	[73]	-4	hSpCas9	negative selection	519953
182585723	182585746	1	+	26472758	Raji	viability	TGAGTTTGCCAATCATAGGGCGG	RNASEL	ENSG00000135828	0.47747362859846865	[488]	[157]	4	hSpCas9	negative selection	519954
182585598	182585621	1	-	26472758	Raji	viability	AGGGCAGCCCACGTGCACAGCGG	RNASEL	ENSG00000135828	0.9919063179536636	[129]	[59]	8	hSpCas9	negative selection	519955
182586754	182586777	1	-	26472758	Raji	viability	GAGGGACCCACGTCCTCCAGCGG	RNASEL	ENSG00000135828	-0.09088609176267476	[256]	[55]	-1	hSpCas9	negative selection	519956
182586329	182586352	1	-	26472758	Raji	viability	TTTGAGGCGAAAGACAAAGGAGG	RNASEL	ENSG00000135828	-0.026472211361191045	[78]	[17]	0	hSpCas9	negative selection	519957
182586233	182586256	1	-	26472758	Raji	viability	GAAGATTCTCCTTGATGAGATGG	RNASEL	ENSG00000135828	0.9025637434851014	[271]	[117]	8	hSpCas9	negative selection	519958
182585776	182585799	1	-	26472758	Raji	viability	AAGCCTCAGAGCTCACACTGGGG	RNASEL	ENSG00000135828	0.13614252835502344	[297]	[75]	1	hSpCas9	negative selection	519959
182585661	182585684	1	-	26472758	Raji	viability	CAGAAGGAGGCATCTACCTGGGG	RNASEL	ENSG00000135828	0.6646736176102012	[385]	[141]	6	hSpCas9	negative selection	519960
182586302	182586325	1	-	26472758	K562	viability	AGAGCGGCTGAGGAAAGGAGGGG	RNASEL	ENSG00000135828	-1.1738070492434445	[301]	[112]	-6	hSpCas9	negative selection	711069
182585617	182585640	1	-	26472758	K562	viability	GCTGTGAAGACGTTCTGTGAGGG	RNASEL	ENSG00000135828	-0.059378547078931865	[1363]	[1104]	0	hSpCas9	negative selection	711070
182585846	182585869	1	+	26472758	K562	viability	GAAGAACCTTCACAAGGGAATGG	RNASEL	ENSG00000135828	0.38824209662878495	[848]	[937]	3	hSpCas9	negative selection	711071
182585723	182585746	1	+	26472758	K562	viability	TGAGTTTGCCAATCATAGGGCGG	RNASEL	ENSG00000135828	0.40824352957234145	[1105]	[1238]	3	hSpCas9	negative selection	711072
182585598	182585621	1	-	26472758	K562	viability	AGGGCAGCCCACGTGCACAGCGG	RNASEL	ENSG00000135828	0.29409388669063663	[313]	[324]	2	hSpCas9	negative selection	711073
182586754	182586777	1	-	26472758	K562	viability	GAGGGACCCACGTCCTCCAGCGG	RNASEL	ENSG00000135828	0.7298455548366887	[539]	[755]	6	hSpCas9	negative selection	711074
182586329	182586352	1	-	26472758	K562	viability	TTTGAGGCGAAAGACAAAGGAGG	RNASEL	ENSG00000135828	1.3783731843353109	[184]	[405]	9	hSpCas9	negative selection	711075
182586233	182586256	1	-	26472758	K562	viability	GAAGATTCTCCTTGATGAGATGG	RNASEL	ENSG00000135828	0.8279449962720842	[334]	[501]	7	hSpCas9	negative selection	711076
182585776	182585799	1	-	26472758	K562	viability	AAGCCTCAGAGCTCACACTGGGG	RNASEL	ENSG00000135828	-0.5170691856338281	[355]	[209]	-3	hSpCas9	negative selection	711077
182585661	182585684	1	-	26472758	K562	viability	CAGAAGGAGGCATCTACCTGGGG	RNASEL	ENSG00000135828	0.20747714927831007	[711]	[693]	1	hSpCas9	negative selection	711078
182575382	182575405	1	+	26627737	DLD1	viability	AATCAGTCCATCAGCACCCAGGG	RNASEL	ENSG00000135828	-0.09815621223577675	[778]	[206,228,243]	-1	hSpCas9	negative selection	767913
182582222	182582245	1	-	26627737	DLD1	viability	GGTCCTCTATGTGGTAAAGAAGG	RNASEL	ENSG00000135828	-1.0475473903017172	[206]	[10,64,20]	-7	hSpCas9	negative selection	767914
182582243	182582266	1	-	26627737	DLD1	viability	TGTGCAGGACCTTGGACGGCTGG	RNASEL	ENSG00000135828	0.9735717982171156	[484]	[364,395,157]	8	hSpCas9	negative selection	767915
182584143	182584166	1	-	26627737	DLD1	viability	TTCTAAGAAAGCTGCTCACCTGG	RNASEL	ENSG00000135828	0.3791820753210965	[246]	[104,106,90]	4	hSpCas9	negative selection	767916
182585525	182585548	1	-	26627737	DLD1	viability	CTATGGGAGTGAGAGCCACAGGG	RNASEL	ENSG00000135828	0.004091273383148963	[911]	[375,246,239]	0	hSpCas9	negative selection	767917
182585526	182585549	1	-	26627737	DLD1	viability	TCTATGGGAGTGAGAGCCACAGG	RNASEL	ENSG00000135828	0.5142600359224716	[343]	[66,227,166]	5	hSpCas9	negative selection	767918
182575382	182575405	1	+	26627737	GBM cells	viability after 5 days	AATCAGTCCATCAGCACCCAGGG	RNASEL	ENSG00000135828	-0.9568814022296717	[370]	[102,101]	-9	hSpCas9	negative selection	850228
182582222	182582245	1	-	26627737	GBM cells	viability after 5 days	GGTCCTCTATGTGGTAAAGAAGG	RNASEL	ENSG00000135828	-0.3162542196828495	[165]	[74,67]	-5	hSpCas9	negative selection	850229
182582243	182582266	1	-	26627737	GBM cells	viability after 5 days	TGTGCAGGACCTTGGACGGCTGG	RNASEL	ENSG00000135828	0.04200083083278064	[210]	[109,122]	0	hSpCas9	negative selection	850230
182584143	182584166	1	-	26627737	GBM cells	viability after 5 days	TTCTAAGAAAGCTGCTCACCTGG	RNASEL	ENSG00000135828	0.36794626380525863	[176]	[126,117]	5	hSpCas9	negative selection	850231
182585525	182585548	1	-	26627737	GBM cells	viability after 5 days	CTATGGGAGTGAGAGCCACAGGG	RNASEL	ENSG00000135828	0.3047680519991939	[393]	[219,301]	5	hSpCas9	negative selection	850232
182585526	182585549	1	-	26627737	GBM cells	viability after 5 days	TCTATGGGAGTGAGAGCCACAGG	RNASEL	ENSG00000135828	0.7718019569823464	[82]	[91,59]	9	hSpCas9	negative selection	850233
182575382	182575405	1	+	26627737	GBM cells	viability after 13 days	AATCAGTCCATCAGCACCCAGGG	RNASEL	ENSG00000135828	-0.16474136241418724	[370]	[151,201]	-2	hSpCas9	negative selection	932543
182582222	182582245	1	-	26627737	GBM cells	viability after 13 days	GGTCCTCTATGTGGTAAAGAAGG	RNASEL	ENSG00000135828	-0.6513257131420033	[165]	[58,55]	-6	hSpCas9	negative selection	932544
182582243	182582266	1	-	26627737	GBM cells	viability after 13 days	TGTGCAGGACCTTGGACGGCTGG	RNASEL	ENSG00000135828	0.39926816335708815	[210]	[193,115]	5	hSpCas9	negative selection	932545
182584143	182584166	1	-	26627737	GBM cells	viability after 13 days	TTCTAAGAAAGCTGCTCACCTGG	RNASEL	ENSG00000135828	0.3499226540483704	[176]	[160,90]	4	hSpCas9	negative selection	932546
182585525	182585548	1	-	26627737	GBM cells	viability after 13 days	CTATGGGAGTGAGAGCCACAGGG	RNASEL	ENSG00000135828	0.06332773250269919	[393]	[272,182]	0	hSpCas9	negative selection	932547
182585526	182585549	1	-	26627737	GBM cells	viability after 13 days	TCTATGGGAGTGAGAGCCACAGG	RNASEL	ENSG00000135828	0.3728879188593033	[82]	[70,47]	5	hSpCas9	negative selection	932548
182575382	182575405	1	+	26627737	GBM cells	viability after 21 days	AATCAGTCCATCAGCACCCAGGG	RNASEL	ENSG00000135828	-0.1483928874747107	[370]	[196,167]	-1	hSpCas9	negative selection	1014858
182582222	182582245	1	-	26627737	GBM cells	viability after 21 days	GGTCCTCTATGTGGTAAAGAAGG	RNASEL	ENSG00000135828	-0.07657869609458667	[165]	[84,85]	0	hSpCas9	negative selection	1014859
182582243	182582266	1	-	26627737	GBM cells	viability after 21 days	TGTGCAGGACCTTGGACGGCTGG	RNASEL	ENSG00000135828	0.3735611734279598	[210]	[159,137]	4	hSpCas9	negative selection	1014860
182584143	182584166	1	-	26627737	GBM cells	viability after 21 days	TTCTAAGAAAGCTGCTCACCTGG	RNASEL	ENSG00000135828	-0.13817774045643305	[176]	[101,73]	-1	hSpCas9	negative selection	1014861
182585525	182585548	1	-	26627737	GBM cells	viability after 21 days	CTATGGGAGTGAGAGCCACAGGG	RNASEL	ENSG00000135828	-0.035763848434038126	[393]	[224,193]	0	hSpCas9	negative selection	1014862
182585526	182585549	1	-	26627737	GBM cells	viability after 21 days	TCTATGGGAGTGAGAGCCACAGG	RNASEL	ENSG00000135828	0.9525526546054561	[82]	[80,92]	8	hSpCas9	negative selection	1014863
182575382	182575405	1	+	26627737	RPE1	viability after 9 days	AATCAGTCCATCAGCACCCAGGG	RNASEL	ENSG00000135828	0.007379786948220057	[660]	[238,167]	0	hSpCas9	negative selection	1097173
182582222	182582245	1	-	26627737	RPE1	viability after 9 days	GGTCCTCTATGTGGTAAAGAAGG	RNASEL	ENSG00000135828	2.398139391081708	[94]	[137,180]	9	hSpCas9	negative selection	1097174
182582243	182582266	1	-	26627737	RPE1	viability after 9 days	TGTGCAGGACCTTGGACGGCTGG	RNASEL	ENSG00000135828	1.532910897843524	[448]	[349,479]	8	hSpCas9	negative selection	1097175
182584143	182584166	1	-	26627737	RPE1	viability after 9 days	TTCTAAGAAAGCTGCTCACCTGG	RNASEL	ENSG00000135828	0.3043275073584404	[816]	[331,294]	2	hSpCas9	negative selection	1097176
182585525	182585548	1	-	26627737	RPE1	viability after 9 days	CTATGGGAGTGAGAGCCACAGGG	RNASEL	ENSG00000135828	-0.3246669917406262	[1610]	[386,422]	-2	hSpCas9	negative selection	1097177
182585526	182585549	1	-	26627737	RPE1	viability after 9 days	TCTATGGGAGTGAGAGCCACAGG	RNASEL	ENSG00000135828	-0.11474517695767894	[508]	[106,198]	-1	hSpCas9	negative selection	1097178
182575382	182575405	1	+	26627737	RPE1	viability after 12 days	AATCAGTCCATCAGCACCCAGGG	RNASEL	ENSG00000135828	0.11063397500075481	[660]	[301,74]	0	hSpCas9	negative selection	1179488
182582222	182582245	1	-	26627737	RPE1	viability after 12 days	GGTCCTCTATGTGGTAAAGAAGG	RNASEL	ENSG00000135828	2.852950648884166	[94]	[197,169]	9	hSpCas9	negative selection	1179489
182582243	182582266	1	-	26627737	RPE1	viability after 12 days	TGTGCAGGACCTTGGACGGCTGG	RNASEL	ENSG00000135828	1.1925699870298296	[448]	[265,285]	7	hSpCas9	negative selection	1179490
182584143	182584166	1	-	26627737	RPE1	viability after 12 days	TTCTAAGAAAGCTGCTCACCTGG	RNASEL	ENSG00000135828	0.45786497583403263	[816]	[334,265]	3	hSpCas9	negative selection	1179491
182585525	182585548	1	-	26627737	RPE1	viability after 12 days	CTATGGGAGTGAGAGCCACAGGG	RNASEL	ENSG00000135828	0.20262085606716873	[1610]	[653,332]	1	hSpCas9	negative selection	1179492
182585526	182585549	1	-	26627737	RPE1	viability after 12 days	TCTATGGGAGTGAGAGCCACAGG	RNASEL	ENSG00000135828	-0.9508978521332595	[508]	[61,79]	-6	hSpCas9	negative selection	1179493
182575382	182575405	1	+	26627737	RPE1	viability after 15 days	AATCAGTCCATCAGCACCCAGGG	RNASEL	ENSG00000135828	0.07946349103306152	[660]	[277,119]	0	hSpCas9	negative selection	1261803
182582222	182582245	1	-	26627737	RPE1	viability after 15 days	GGTCCTCTATGTGGTAAAGAAGG	RNASEL	ENSG00000135828	2.8134274489997315	[94]	[165,210]	9	hSpCas9	negative selection	1261804
182582243	182582266	1	-	26627737	RPE1	viability after 15 days	TGTGCAGGACCTTGGACGGCTGG	RNASEL	ENSG00000135828	0.6278341863934254	[448]	[96,291]	4	hSpCas9	negative selection	1261805
182584143	182584166	1	-	26627737	RPE1	viability after 15 days	TTCTAAGAAAGCTGCTCACCTGG	RNASEL	ENSG00000135828	0.7194979579135514	[816]	[433,328]	4	hSpCas9	negative selection	1261806
182585525	182585548	1	-	26627737	RPE1	viability after 15 days	CTATGGGAGTGAGAGCCACAGGG	RNASEL	ENSG00000135828	-0.08955671529903575	[1610]	[383,470]	0	hSpCas9	negative selection	1261807
182585526	182585549	1	-	26627737	RPE1	viability after 15 days	TCTATGGGAGTGAGAGCCACAGG	RNASEL	ENSG00000135828	-0.22861247451053612	[508]	[44,197]	-1	hSpCas9	negative selection	1261808
182575382	182575405	1	+	26627737	RPE1	viability after 18 days	AATCAGTCCATCAGCACCCAGGG	RNASEL	ENSG00000135828	0.24685514923343865	[660]	[376,34]	1	hSpCas9	negative selection	1344118
182582222	182582245	1	-	26627737	RPE1	viability after 18 days	GGTCCTCTATGTGGTAAAGAAGG	RNASEL	ENSG00000135828	3.296549821024986	[94]	[219,285]	9	hSpCas9	negative selection	1344119
182582243	182582266	1	-	26627737	RPE1	viability after 18 days	TGTGCAGGACCTTGGACGGCTGG	RNASEL	ENSG00000135828	1.3547136491758112	[448]	[262,359]	7	hSpCas9	negative selection	1344120
182584143	182584166	1	-	26627737	RPE1	viability after 18 days	TTCTAAGAAAGCTGCTCACCTGG	RNASEL	ENSG00000135828	-0.04494333660658886	[816]	[292,128]	0	hSpCas9	negative selection	1344121
182585525	182585548	1	-	26627737	RPE1	viability after 18 days	CTATGGGAGTGAGAGCCACAGGG	RNASEL	ENSG00000135828	-0.2431699432796326	[1610]	[332,403]	-1	hSpCas9	negative selection	1344122
182585526	182585549	1	-	26627737	RPE1	viability after 18 days	TCTATGGGAGTGAGAGCCACAGG	RNASEL	ENSG00000135828	-0.22367915452426923	[508]	[106,128]	-1	hSpCas9	negative selection	1344123
182575382	182575405	1	+	26627737	HeLa	viability after 8 days	AATCAGTCCATCAGCACCCAGGG	RNASEL	ENSG00000135828	-0.09473497276412701	[257]	[93,173,48]	-1	hSpCas9	negative selection	1426433
182582222	182582245	1	-	26627737	HeLa	viability after 8 days	GGTCCTCTATGTGGTAAAGAAGG	RNASEL	ENSG00000135828	-0.36776339754453	[259]	[155,62,60]	-4	hSpCas9	negative selection	1426434
182582243	182582266	1	-	26627737	HeLa	viability after 8 days	TGTGCAGGACCTTGGACGGCTGG	RNASEL	ENSG00000135828	-0.9665985061353678	[966]	[99,207,305]	-7	hSpCas9	negative selection	1426435
182584143	182584166	1	-	26627737	HeLa	viability after 8 days	TTCTAAGAAAGCTGCTCACCTGG	RNASEL	ENSG00000135828	-0.9841549688090173	[405]	[237,22,42]	-7	hSpCas9	negative selection	1426436
182585525	182585548	1	-	26627737	HeLa	viability after 8 days	CTATGGGAGTGAGAGCCACAGGG	RNASEL	ENSG00000135828	-0.11002657938108018	[895]	[372,435,282]	-1	hSpCas9	negative selection	1426437
182585526	182585549	1	-	26627737	HeLa	viability after 8 days	TCTATGGGAGTGAGAGCCACAGG	RNASEL	ENSG00000135828	-2.053996475162626	[482]	[112,37,16]	-9	hSpCas9	negative selection	1426438
182575382	182575405	1	+	26627737	HeLa	viability after 12 days	AATCAGTCCATCAGCACCCAGGG	RNASEL	ENSG00000135828	-0.29463280465664254	[257]	[47,177,23]	-3	hSpCas9	negative selection	1508748
182582222	182582245	1	-	26627737	HeLa	viability after 12 days	GGTCCTCTATGTGGTAAAGAAGG	RNASEL	ENSG00000135828	0.36837792588439155	[259]	[201,109,108]	3	hSpCas9	negative selection	1508749
182582243	182582266	1	-	26627737	HeLa	viability after 12 days	TGTGCAGGACCTTGGACGGCTGG	RNASEL	ENSG00000135828	-1.2110733066505983	[966]	[96,225,186]	-8	hSpCas9	negative selection	1508750
182584143	182584166	1	-	26627737	HeLa	viability after 12 days	TTCTAAGAAAGCTGCTCACCTGG	RNASEL	ENSG00000135828	-0.6857025954041164	[405]	[48,97,164]	-6	hSpCas9	negative selection	1508751
182585525	182585548	1	-	26627737	HeLa	viability after 12 days	CTATGGGAGTGAGAGCCACAGGG	RNASEL	ENSG00000135828	-0.4551405018795218	[895]	[233,347,218]	-4	hSpCas9	negative selection	1508752
182585526	182585549	1	-	26627737	HeLa	viability after 12 days	TCTATGGGAGTGAGAGCCACAGG	RNASEL	ENSG00000135828	-1.5224473964222773	[482]	[19,78,106]	-8	hSpCas9	negative selection	1508753
182575382	182575405	1	+	26627737	HeLa	viability after 15 days	AATCAGTCCATCAGCACCCAGGG	RNASEL	ENSG00000135828	0.3547584441261165	[257]	[175,108,115]	3	hSpCas9	negative selection	1591063
182582222	182582245	1	-	26627737	HeLa	viability after 15 days	GGTCCTCTATGTGGTAAAGAAGG	RNASEL	ENSG00000135828	-0.20149774621157635	[259]	[79,119,74]	-2	hSpCas9	negative selection	1591064
182582243	182582266	1	-	26627737	HeLa	viability after 15 days	TGTGCAGGACCTTGGACGGCTGG	RNASEL	ENSG00000135828	-0.4881777491995284	[966]	[391,125,325]	-4	hSpCas9	negative selection	1591065
182584143	182584166	1	-	26627737	HeLa	viability after 15 days	TTCTAAGAAAGCTGCTCACCTGG	RNASEL	ENSG00000135828	-0.006015696622463616	[405]	[130,152,213]	0	hSpCas9	negative selection	1591066
182585525	182585548	1	-	26627737	HeLa	viability after 15 days	CTATGGGAGTGAGAGCCACAGGG	RNASEL	ENSG00000135828	-0.08995182822688119	[895]	[333,402,286]	0	hSpCas9	negative selection	1591067
182585526	182585549	1	-	26627737	HeLa	viability after 15 days	TCTATGGGAGTGAGAGCCACAGG	RNASEL	ENSG00000135828	-2.2635416292857404	[482]	[5,79,36]	-9	hSpCas9	negative selection	1591068
182575382	182575405	1	+	26627737	HeLa	viability after 18 days	AATCAGTCCATCAGCACCCAGGG	RNASEL	ENSG00000135828	0.3988393657598399	[257]	[123,92,115]	3	hSpCas9	negative selection	1673378
182582222	182582245	1	-	26627737	HeLa	viability after 18 days	GGTCCTCTATGTGGTAAAGAAGG	RNASEL	ENSG00000135828	-0.22397396432898287	[259]	[51,97,74]	-2	hSpCas9	negative selection	1673379
182582243	182582266	1	-	26627737	HeLa	viability after 18 days	TGTGCAGGACCTTGGACGGCTGG	RNASEL	ENSG00000135828	-0.45806193927389804	[966]	[273,104,325]	-4	hSpCas9	negative selection	1673380
182584143	182584166	1	-	26627737	HeLa	viability after 18 days	TTCTAAGAAAGCTGCTCACCTGG	RNASEL	ENSG00000135828	0.016131739372773297	[405]	[90,128,213]	0	hSpCas9	negative selection	1673381
182585525	182585548	1	-	26627737	HeLa	viability after 18 days	CTATGGGAGTGAGAGCCACAGGG	RNASEL	ENSG00000135828	-0.05416855666089848	[895]	[230,345,286]	0	hSpCas9	negative selection	1673382
182585526	182585549	1	-	26627737	HeLa	viability after 18 days	TCTATGGGAGTGAGAGCCACAGG	RNASEL	ENSG00000135828	-2.2070560871350207	[482]	[4,68,36]	-9	hSpCas9	negative selection	1673383
182575382	182575405	1	+	26627737	HCT116	viability after 6 days	AATCAGTCCATCAGCACCCAGGG	RNASEL	ENSG00000135828	-2.0963773275961164	[624]	[31,17]	-8	hSpCas9	negative selection	1755693
182582222	182582245	1	-	26627737	HCT116	viability after 6 days	GGTCCTCTATGTGGTAAAGAAGG	RNASEL	ENSG00000135828	1.7738283284065313	[201]	[18,157]	8	hSpCas9	negative selection	1755694
182582243	182582266	1	-	26627737	HCT116	viability after 6 days	TGTGCAGGACCTTGGACGGCTGG	RNASEL	ENSG00000135828	0.22594139289496856	[763]	[124,148]	1	hSpCas9	negative selection	1755695
182584143	182584166	1	-	26627737	HCT116	viability after 6 days	TTCTAAGAAAGCTGCTCACCTGG	RNASEL	ENSG00000135828	-0.3536892059877291	[484]	[49,64]	-2	hSpCas9	negative selection	1755696
182585525	182585548	1	-	26627737	HCT116	viability after 6 days	CTATGGGAGTGAGAGCCACAGGG	RNASEL	ENSG00000135828	1.2074389910456635	[692]	[491,118]	6	hSpCas9	negative selection	1755697
182585526	182585549	1	-	26627737	HCT116	viability after 6 days	TCTATGGGAGTGAGAGCCACAGG	RNASEL	ENSG00000135828	2.478621596397031	[143]	[4,192]	9	hSpCas9	negative selection	1755698
182575382	182575405	1	+	26627737	HCT116	viability after 8 days	AATCAGTCCATCAGCACCCAGGG	RNASEL	ENSG00000135828	0.0720608252946231	[225]	[109,121,159]	0	hSpCas9	negative selection	1838008
182582222	182582245	1	-	26627737	HCT116	viability after 8 days	GGTCCTCTATGTGGTAAAGAAGG	RNASEL	ENSG00000135828	0.44482336695305946	[141]	[116,120,81]	4	hSpCas9	negative selection	1838009
182582243	182582266	1	-	26627737	HCT116	viability after 8 days	TGTGCAGGACCTTGGACGGCTGG	RNASEL	ENSG00000135828	0.29095948388091947	[406]	[150,317,350]	3	hSpCas9	negative selection	1838010
182584143	182584166	1	-	26627737	HCT116	viability after 8 days	TTCTAAGAAAGCTGCTCACCTGG	RNASEL	ENSG00000135828	0.5969881660446029	[132]	[163,99,69]	6	hSpCas9	negative selection	1838011
182585525	182585548	1	-	26627737	HCT116	viability after 8 days	CTATGGGAGTGAGAGCCACAGGG	RNASEL	ENSG00000135828	0.5222149854554109	[365]	[282,312,272]	5	hSpCas9	negative selection	1838012
182585526	182585549	1	-	26627737	HCT116	viability after 8 days	TCTATGGGAGTGAGAGCCACAGG	RNASEL	ENSG00000135828	-0.9574104853940759	[214]	[59,60,61]	-8	hSpCas9	negative selection	1838013
182575382	182575405	1	+	26627737	HCT116	viability after 9 days	AATCAGTCCATCAGCACCCAGGG	RNASEL	ENSG00000135828	0.4141501447000032	[624]	[151,277]	3	hSpCas9	negative selection	1920323
182582222	182582245	1	-	26627737	HCT116	viability after 9 days	GGTCCTCTATGTGGTAAAGAAGG	RNASEL	ENSG00000135828	0.3393926354992436	[201]	[22,103]	2	hSpCas9	negative selection	1920324
182582243	182582266	1	-	26627737	HCT116	viability after 9 days	TGTGCAGGACCTTGGACGGCTGG	RNASEL	ENSG00000135828	-0.08659676193937116	[763]	[376,45]	0	hSpCas9	negative selection	1920325
182584143	182584166	1	-	26627737	HCT116	viability after 9 days	TTCTAAGAAAGCTGCTCACCTGG	RNASEL	ENSG00000135828	-1.4026718792730255	[484]	[10,78]	-7	hSpCas9	negative selection	1920326
182585525	182585548	1	-	26627737	HCT116	viability after 9 days	CTATGGGAGTGAGAGCCACAGGG	RNASEL	ENSG00000135828	0.9822369879460011	[692]	[302,414]	6	hSpCas9	negative selection	1920327
182585526	182585549	1	-	26627737	HCT116	viability after 9 days	TCTATGGGAGTGAGAGCCACAGG	RNASEL	ENSG00000135828	0.9940657883185509	[143]	[70,80]	7	hSpCas9	negative selection	1920328
182575382	182575405	1	+	26627737	HCT116	viability after 12 days	AATCAGTCCATCAGCACCCAGGG	RNASEL	ENSG00000135828	0.06625680911355458	[225]	[83,140,151]	0	hSpCas9	negative selection	2002638
182582222	182582245	1	-	26627737	HCT116	viability after 12 days	GGTCCTCTATGTGGTAAAGAAGG	RNASEL	ENSG00000135828	0.07411883938824215	[141]	[82,107,44]	0	hSpCas9	negative selection	2002639
182582243	182582266	1	-	26627737	HCT116	viability after 12 days	TGTGCAGGACCTTGGACGGCTGG	RNASEL	ENSG00000135828	-0.41519306782854193	[406]	[159,191,129]	-4	hSpCas9	negative selection	2002640
182584143	182584166	1	-	26627737	HCT116	viability after 12 days	TTCTAAGAAAGCTGCTCACCTGG	RNASEL	ENSG00000135828	0.22593400575190048	[132]	[97,130,15]	2	hSpCas9	negative selection	2002641
182585525	182585548	1	-	26627737	HCT116	viability after 12 days	CTATGGGAGTGAGAGCCACAGGG	RNASEL	ENSG00000135828	0.713337352433134	[365]	[348,350,243]	6	hSpCas9	negative selection	2002642
182585526	182585549	1	-	26627737	HCT116	viability after 12 days	TCTATGGGAGTGAGAGCCACAGG	RNASEL	ENSG00000135828	-0.3310033945301536	[214]	[32,111,129]	-4	hSpCas9	negative selection	2002643
182575382	182575405	1	+	26627737	HCT116	viability after 15 days	AATCAGTCCATCAGCACCCAGGG	RNASEL	ENSG00000135828	-0.3990174848660884	[225]	[92,133,67]	-4	hSpCas9	negative selection	2084953
182582222	182582245	1	-	26627737	HCT116	viability after 15 days	GGTCCTCTATGTGGTAAAGAAGG	RNASEL	ENSG00000135828	0.9620935549770862	[141]	[168,79,227]	7	hSpCas9	negative selection	2084954
182582243	182582266	1	-	26627737	HCT116	viability after 15 days	TGTGCAGGACCTTGGACGGCTGG	RNASEL	ENSG00000135828	0.19082039644476984	[406]	[529,167,135]	2	hSpCas9	negative selection	2084955
182584143	182584166	1	-	26627737	HCT116	viability after 15 days	TTCTAAGAAAGCTGCTCACCTGG	RNASEL	ENSG00000135828	1.0799283451991304	[132]	[260,114,120]	8	hSpCas9	negative selection	2084956
182585525	182585548	1	-	26627737	HCT116	viability after 15 days	CTATGGGAGTGAGAGCCACAGGG	RNASEL	ENSG00000135828	0.6222461883567278	[365]	[344,367,260]	5	hSpCas9	negative selection	2084957
182585526	182585549	1	-	26627737	HCT116	viability after 15 days	TCTATGGGAGTGAGAGCCACAGG	RNASEL	ENSG00000135828	-1.1989190444904279	[214]	[57,60,42]	-8	hSpCas9	negative selection	2084958
182575382	182575405	1	+	26627737	HCT116	viability after 18 days	AATCAGTCCATCAGCACCCAGGG	RNASEL	ENSG00000135828	0.29606813749732974	[225]	[92,171,134]	2	hSpCas9	negative selection	2167268
182582222	182582245	1	-	26627737	HCT116	viability after 18 days	GGTCCTCTATGTGGTAAAGAAGG	RNASEL	ENSG00000135828	0.18496580793037032	[141]	[103,76,51]	1	hSpCas9	negative selection	2167269
182582243	182582266	1	-	26627737	HCT116	viability after 18 days	TGTGCAGGACCTTGGACGGCTGG	RNASEL	ENSG00000135828	0.23617732057578916	[406]	[260,324,96]	2	hSpCas9	negative selection	2167270
182584143	182584166	1	-	26627737	HCT116	viability after 18 days	TTCTAAGAAAGCTGCTCACCTGG	RNASEL	ENSG00000135828	1.3241385457749004	[132]	[177,170,131]	8	hSpCas9	negative selection	2167271
182585525	182585548	1	-	26627737	HCT116	viability after 18 days	CTATGGGAGTGAGAGCCACAGGG	RNASEL	ENSG00000135828	0.9381804177506591	[365]	[389,284,345]	7	hSpCas9	negative selection	2167272
182585526	182585549	1	-	26627737	HCT116	viability after 18 days	TCTATGGGAGTGAGAGCCACAGG	RNASEL	ENSG00000135828	-0.3164421764777231	[214]	[149,33,68]	-3	hSpCas9	negative selection	2167273
182586633	182586656	1	-	24336569	HL60	viability	TTAATTTCCAGGAAGAGGAAGGG	RNASEL	ENSG00000135828	0.36240608085766013	[643]	[1751]	3	hSpCas9	negative selection	2289838
182586638	182586661	1	-	24336569	HL60	viability	CAATGTTAATTTCCAGGAAGAGG	RNASEL	ENSG00000135828	0.35584077692317423	[441]	[1196]	3	hSpCas9	negative selection	2289839
182586644	182586667	1	-	24336569	HL60	viability	TGGAGCCAATGTTAATTTCCAGG	RNASEL	ENSG00000135828	-0.412178661425353	[946]	[1505]	-4	hSpCas9	negative selection	2289840
182586662	182586685	1	+	24336569	HL60	viability	CTCCACCTTCCAGCAATTGCTGG	RNASEL	ENSG00000135828	0.03210742507596548	[640]	[1386]	0	hSpCas9	negative selection	2289841
182586667	182586690	1	-	24336569	HL60	viability	CTGGTCCAGCAATTGCTGGAAGG	RNASEL	ENSG00000135828	1.247297376084887	[336]	[1692]	8	hSpCas9	negative selection	2289842
182586737	182586760	1	-	24336569	HL60	viability	CAGCGGTAGAAGGGCTGCAGTGG	RNASEL	ENSG00000135828	0.8065237813032275	[926]	[3430]	6	hSpCas9	negative selection	2289843
182586746	182586769	1	-	24336569	HL60	viability	CACGTCCTCCAGCGGTAGAAGGG	RNASEL	ENSG00000135828	0.666748198712044	[689]	[2317]	5	hSpCas9	negative selection	2289844
182586754	182586777	1	-	24336569	HL60	viability	GAGGGACCCACGTCCTCCAGCGG	RNASEL	ENSG00000135828	-0.7702367477693025	[838]	[1040]	-6	hSpCas9	negative selection	2289845
182586759	182586782	1	+	24336569	HL60	viability	GGAGGACGTGGGTCCCTCCTGGG	RNASEL	ENSG00000135828	1.4105254143137957	[234]	[1321]	8	hSpCas9	negative selection	2289846
182586794	182586817	1	-	24336569	HL60	viability	ATTTACCGTCATGGAGAGCAGGG	RNASEL	ENSG00000135828	-0.3878681346109365	[958]	[1550]	-3	hSpCas9	negative selection	2289847
182586633	182586656	1	-	24336569	KBM7	viability	TTAATTTCCAGGAAGAGGAAGGG	RNASEL	ENSG00000135828	0.7169016662033021	[471]	[2115]	6	hSpCas9	negative selection	2357015
182586638	182586661	1	-	24336569	KBM7	viability	CAATGTTAATTTCCAGGAAGAGG	RNASEL	ENSG00000135828	1.371010929511705	[200]	[1417]	9	hSpCas9	negative selection	2357016
182586644	182586667	1	-	24336569	KBM7	viability	TGGAGCCAATGTTAATTTCCAGG	RNASEL	ENSG00000135828	0.7186904659692158	[482]	[2167]	6	hSpCas9	negative selection	2357017
182586662	182586685	1	+	24336569	KBM7	viability	CTCCACCTTCCAGCAATTGCTGG	RNASEL	ENSG00000135828	0.425814487071549	[365]	[1340]	4	hSpCas9	negative selection	2357018
182586667	182586690	1	-	24336569	KBM7	viability	CTGGTCCAGCAATTGCTGGAAGG	RNASEL	ENSG00000135828	0.5235659407789325	[403]	[1583]	5	hSpCas9	negative selection	2357019
182586737	182586760	1	-	24336569	KBM7	viability	CAGCGGTAGAAGGGCTGCAGTGG	RNASEL	ENSG00000135828	0.27915447500636725	[848]	[2809]	2	hSpCas9	negative selection	2357020
182586746	182586769	1	-	24336569	KBM7	viability	CACGTCCTCCAGCGGTAGAAGGG	RNASEL	ENSG00000135828	0.8062618552022895	[550]	[2627]	7	hSpCas9	negative selection	2357021
182586754	182586777	1	-	24336569	KBM7	viability	GAGGGACCCACGTCCTCCAGCGG	RNASEL	ENSG00000135828	0.6491359579396532	[255]	[1094]	6	hSpCas9	negative selection	2357022
182586759	182586782	1	+	24336569	KBM7	viability	GGAGGACGTGGGTCCCTCCTGGG	RNASEL	ENSG00000135828	0.2999778088850391	[379]	[1275]	2	hSpCas9	negative selection	2357023
182586794	182586817	1	-	24336569	KBM7	viability	ATTTACCGTCATGGAGAGCAGGG	RNASEL	ENSG00000135828	0.39244191442904364	[785]	[2813]	3	hSpCas9	negative selection	2357024
182585852	182585875	1	-	27013184	SW480	treatment with recombinant TRAIL	TTATGACCATTCCCTTGTGAAGG	RNASEL	ENSG00000135828	-1.2011936574451454	[1,20]	[1,1]	-5	hSpCas9	positive selection	2960312
182585877	182585900	1	-	27013184	SW480	treatment with recombinant TRAIL	ATCTTGTTATGACAGCGAGGCGG	RNASEL	ENSG00000135828	2.844795263639932	[95,185]	[517,291]	9	hSpCas9	positive selection	2960313
182585901	182585924	1	-	27013184	SW480	treatment with recombinant TRAIL	GTGGAGCCAGTACAGATTGTGGG	RNASEL	ENSG00000135828	2.3666528099203976	[74,98]	[156,239]	8	hSpCas9	positive selection	2960314
182586128	182586151	1	-	27013184	SW480	treatment with recombinant TRAIL	GGCTATTACGCATCTGCTGCTGG	RNASEL	ENSG00000135828	-0.3621966905857352	[848,924]	[268,335]	-2	hSpCas9	positive selection	2960315
182586149	182586172	1	-	27013184	SW480	treatment with recombinant TRAIL	CTCTGACGATAGTGATGTGGAGG	RNASEL	ENSG00000135828	1.494731884073365	[38,80]	[99,28]	7	hSpCas9	positive selection	2960316
182586202	182586225	1	-	27013184	SW480	treatment with recombinant TRAIL	GTAAACGCCTGTGACAATATGGG	RNASEL	ENSG00000135828	-1.3584911426932251	[125,89]	[29,1]	-6	hSpCas9	positive selection	2960317
182586271	182586294	1	-	27013184	SW480	treatment with recombinant TRAIL	CTCATGGACGCTGCTGAAAAAGG	RNASEL	ENSG00000135828	0.43959380222791977	[77,151]	[78,45]	2	hSpCas9	positive selection	2960318
182586738	182586761	1	+	27013184	SW480	treatment with recombinant TRAIL	CACTGCAGCCCTTCTACCGCTGG	RNASEL	ENSG00000135828	-2.234801897459454	[738,774]	[34,117]	-8	hSpCas9	positive selection	2960319
182586741	182586764	1	+	27013184	SW480	treatment with recombinant TRAIL	TGCAGCCCTTCTACCGCTGGAGG	RNASEL	ENSG00000135828	1.1518536478210564	[270,564]	[443,308]	5	hSpCas9	positive selection	2960320
182586747	182586770	1	+	27013184	SW480	treatment with recombinant TRAIL	CCTTCTACCGCTGGAGGACGTGG	RNASEL	ENSG00000135828	0.14378635918167687	[194,124]	[130,1]	0	hSpCas9	positive selection	2960321
182586748	182586771	1	+	27013184	SW480	treatment with recombinant TRAIL	CTTCTACCGCTGGAGGACGTGGG	RNASEL	ENSG00000135828	-0.9322474993740801	[813,905]	[129,283]	-4	hSpCas9	positive selection	2960322
182586789	182586812	1	+	27013184	SW480	treatment with recombinant TRAIL	ATGATCCCTGCTCTCCATGACGG	RNASEL	ENSG00000135828	1.0982877944562033	[106,183]	[115,152]	5	hSpCas9	positive selection	2960323
182585590	182585613	1	+	27013184	SW480	treatment with recombinant TRAIL	GAGACTTCCCGCTGTGCACGTGG	RNASEL	ENSG00000135828	0.09688140560779379	[880,946]	[242,672]	0	hSpCas9	positive selection	2960324
182585720	182585743	1	+	27013184	SW480	treatment with recombinant TRAIL	ACTTGAGTTTGCCAATCATAGGG	RNASEL	ENSG00000135828	-4.252339705200807	[301,289]	[2,11]	-9	hSpCas9	positive selection	2960325
182586494	182586517	1	+	27013184	SW480	treatment with recombinant TRAIL	CGCTCCCCGCAATCGCTGCGAGG	RNASEL	ENSG00000135828	0.26623051170672607	[822,1022]	[291,733]	1	hSpCas9	positive selection	2960326
182586395	182586418	1	-	27013184	SW480	treatment with recombinant TRAIL	GGAAGCCGCTGTGTATGGTAAGG	RNASEL	ENSG00000135828	0.8410631653624137	[185,316]	[146,250]	4	hSpCas9	positive selection	2960327
182586498	182586521	1	-	27013184	SW480	treatment with recombinant TRAIL	TTATCCTCGCAGCGATTGCGGGG	RNASEL	ENSG00000135828	-1.6795349909854589	[288,534]	[39,73]	-6	hSpCas9	positive selection	2960328
182586499	182586522	1	-	27013184	SW480	treatment with recombinant TRAIL	TTTATCCTCGCAGCGATTGCGGG	RNASEL	ENSG00000135828	-0.091251973772978	[61,67]	[5,54]	0	hSpCas9	positive selection	2960329
182586500	182586523	1	-	27013184	SW480	treatment with recombinant TRAIL	TTTTATCCTCGCAGCGATTGCGG	RNASEL	ENSG00000135828	0.12697561720497286	[281,325]	[72,240]	0	hSpCas9	positive selection	2960330
182586594	182586617	1	-	27013184	SW480	treatment with recombinant TRAIL	ATAACGCAGTACAAATGAGCAGG	RNASEL	ENSG00000135828	0.8300969910716477	[205,187]	[107,213]	4	hSpCas9	positive selection	2960331
182586686	182586709	1	-	27013184	SW480	treatment with recombinant TRAIL	TCAAAACGAAGATGTTGACCTGG	RNASEL	ENSG00000135828	-3.977350747868554	[72,72]	[1,1]	-9	hSpCas9	positive selection	2960332
182586737	182586760	1	-	27013184	SW480	treatment with recombinant TRAIL	CAGCGGTAGAAGGGCTGCAGTGG	RNASEL	ENSG00000135828	1.2242027626800516	[43,5]	[16,40]	6	hSpCas9	positive selection	2960333
182586746	182586769	1	-	27013184	SW480	treatment with recombinant TRAIL	CACGTCCTCCAGCGGTAGAAGGG	RNASEL	ENSG00000135828	1.2336981420945987	[1186,632]	[907,1005]	6	hSpCas9	positive selection	2960334
182586747	182586770	1	-	27013184	SW480	treatment with recombinant TRAIL	CCACGTCCTCCAGCGGTAGAAGG	RNASEL	ENSG00000135828	3.18846830191978	[79,83]	[396,214]	9	hSpCas9	positive selection	2960335
182586794	182586817	1	-	27013184	SW480	treatment with recombinant TRAIL	ATTTACCGTCATGGAGAGCAGGG	RNASEL	ENSG00000135828	-1.6472658190016967	[409,440]	[24,105]	-6	hSpCas9	positive selection	2960336
182586795	182586818	1	-	27013184	SW480	treatment with recombinant TRAIL	CATTTACCGTCATGGAGAGCAGG	RNASEL	ENSG00000135828	-1.3286968605632667	[370,349]	[71,47]	-6	hSpCas9	positive selection	2960337
182586803	182586826	1	-	27013184	SW480	treatment with recombinant TRAIL	GCAGGTGGCATTTACCGTCATGG	RNASEL	ENSG00000135828	-0.026633550464209732	[265,232]	[95,120]	0	hSpCas9	positive selection	2960338
182585542	182585565	1	-	27013184	SW480	treatment with recombinant TRAIL	AGTCACTTGGTGACATTCTATGG	RNASEL	ENSG00000135828	-1.7195833087543329	[318,294]	[60,10]	-7	hSpCas9	positive selection	2960339
182585663	182585686	1	-	27013184	SW480	treatment with recombinant TRAIL	TTCAGAAGGAGGCATCTACCTGG	RNASEL	ENSG00000135828	-1.4817646110337184	[8,25]	[2,1]	-6	hSpCas9	positive selection	2960340
182585731	182585754	1	-	27013184	SW480	treatment with recombinant TRAIL	AGAATATACCGCCCTATGATTGG	RNASEL	ENSG00000135828	0.6928258334525021	[257,310]	[98,335]	3	hSpCas9	positive selection	2960341
182586090	182586113	1	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TCAATGTGAGGGGAGAAAGAGGG	RNASEL	ENSG00000135828	0.08475975951499648	[4,5]	[5,3]	1	hSpCas9	positive selection	3017076
182585724	182585747	1	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TGAGTTTGCCAATCATAGGGCGG	RNASEL	ENSG00000135828	0.09656692582271278	[3,4]	[4,3]	2	hSpCas9	positive selection	3017077
182586498	182586521	1	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TTATCCTCGCAGCGATTGCGGGG	RNASEL	ENSG00000135828	0.15371737712508077	[3,3]	[1,4]	3	hSpCas9	positive selection	3017078
182586391	182586414	1	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TTTGACCTTACCATACACAGCGG	RNASEL	ENSG00000135828	0.27607465081496546	[4,4]	[5,3]	6	hSpCas9	positive selection	3017079
182586090	182586113	1	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TCAATGTGAGGGGAGAAAGAGGG	RNASEL	ENSG00000135828	0.4613579487981301	[4,4]	[4,4]	7	hSpCas9	positive selection	3084934
182585724	182585747	1	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TGAGTTTGCCAATCATAGGGCGG	RNASEL	ENSG00000135828	0.5436457364096596	[3,3]	[4,3]	8	hSpCas9	positive selection	3084935
182586498	182586521	1	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TTATCCTCGCAGCGATTGCGGGG	RNASEL	ENSG00000135828	-0.4124439585711293	[3,3]	[2,0]	-6	hSpCas9	positive selection	3084936
182586391	182586414	1	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TTTGACCTTACCATACACAGCGG	RNASEL	ENSG00000135828	0.19686709680668962	[4,4]	[4,2]	3	hSpCas9	positive selection	3084937
182582116	182582139		-	24336571	A375	resistance to PLX after 7 days	ATTCATCGTCTCTTCCATCCTGG	RNASEL	ENSG00000135828	0.16610034817397934	[29,27]	[32,31]	5	hSpCas9	positive selection	3141151
182582153	182582176		-	24336571	A375	resistance to PLX after 7 days	GGTTCAACTTTCTCCAGATGAGG	RNASEL	ENSG00000135828	-0.026401957614482052	[5,5]	[5,5]	0	hSpCas9	positive selection	3141152
182582058	182582081		-	24336571	A375	resistance to PLX after 7 days	GTCATCCCTTCTTTTGGACTTGG	RNASEL	ENSG00000135828	-0.24024965462735812	[16,13]	[12,12]	-7	hSpCas9	positive selection	3141154
182584125	182584148		+	24336571	A375	resistance to PLX after 7 days	TGCTCTTATCAAAATCTGCCAGG	RNASEL	ENSG00000135828	0.2245068741520494	[8,8]	[10,8]	6	hSpCas9	positive selection	3141155
182582116	182582139		-	24336571	A375	resistance to PLX after 14 days	ATTCATCGTCTCTTCCATCCTGG	RNASEL	ENSG00000135828	0.2802465472523823	[30,33]	[16,19]	3	hSpCas9	positive selection	3198944
182582153	182582176		-	24336571	A375	resistance to PLX after 14 days	GGTTCAACTTTCTCCAGATGAGG	RNASEL	ENSG00000135828	0.4655281547916984	[5,5]	[3,2]	4	hSpCas9	positive selection	3198945
182582058	182582081		-	24336571	A375	resistance to PLX after 14 days	GTCATCCCTTCTTTTGGACTTGG	RNASEL	ENSG00000135828	-0.45697665535969967	[17,14]	[4,5]	-5	hSpCas9	positive selection	3198947
182584125	182584148		+	24336571	A375	resistance to PLX after 14 days	TGCTCTTATCAAAATCTGCCAGG	RNASEL	ENSG00000135828	-1.0302946868357472	[11,11]	[2,1]	-9	hSpCas9	positive selection	3198948
182582116	182582139		-	24336571	A375	viability after 7 days	ATTCATCGTCTCTTCCATCCTGG	RNASEL	ENSG00000135828	0.15284582729537144	[27]	[29,27]	2	hSpCas9	negative selection	3256737
182582153	182582176		-	24336571	A375	viability after 7 days	GGTTCAACTTTCTCCAGATGAGG	RNASEL	ENSG00000135828	0.18655496856197584	[5]	[5,5]	3	hSpCas9	negative selection	3256738
182582058	182582081		-	24336571	A375	viability after 7 days	GTCATCCCTTCTTTTGGACTTGG	RNASEL	ENSG00000135828	0.09217803236214428	[14]	[16,13]	1	hSpCas9	negative selection	3256740
182584125	182584148		+	24336571	A375	viability after 7 days	TGCTCTTATCAAAATCTGCCAGG	RNASEL	ENSG00000135828	-0.4329440301844759	[11]	[8,8]	-6	hSpCas9	negative selection	3256741
182582116	182582139		-	24336571	A375	viability after 14 days	ATTCATCGTCTCTTCCATCCTGG	RNASEL	ENSG00000135828	0.3232990522742658	[27]	[30,33]	4	hSpCas9	negative selection	3314530
182582153	182582176		-	24336571	A375	viability after 14 days	GGTTCAACTTTCTCCAGATGAGG	RNASEL	ENSG00000135828	0.1821120699837271	[5]	[5,5]	2	hSpCas9	negative selection	3314531
182582058	182582081		-	24336571	A375	viability after 14 days	GTCATCCCTTCTTTTGGACTTGG	RNASEL	ENSG00000135828	0.22836928608681017	[14]	[17,14]	3	hSpCas9	negative selection	3314533
182584125	182584148		+	24336571	A375	viability after 14 days	TGCTCTTATCAAAATCTGCCAGG	RNASEL	ENSG00000135828	0.03267145915550179	[11]	[11,11]	0	hSpCas9	negative selection	3314534
182582081	182582104	1	-	27383988	293T	resistance to West Nile virus (flavivirus)	GGACTGTCTGAGTGACCTGCTGG	RNASEL	ENSG00000135828	-0.7979562240553546	[265,265]	[0,0]	-5	hSpCas9	positive selection	3390018
182584125	182584148	1	+	27383988	293T	resistance to West Nile virus (flavivirus)	TGCTCTTATCAAAATCTGCCAGG	RNASEL	ENSG00000135828	-0.8407058715146917	[273,273]	[0,0]	-6	hSpCas9	positive selection	3390019
182576308	182576331	1	+	27383988	293T	resistance to West Nile virus (flavivirus)	GCAGATCACCCACAGTGTTCTGG	RNASEL	ENSG00000135828	1.3746831620839939	[58,58]	[0,0]	6	hSpCas9	positive selection	3390020
182586090	182586113	1	-	26780180	HT29	viability (Avana library 4 designs)	TCAATGTGAGGGGAGAAAGAGGG	RNASEL	ENSG00000135828	0.56295980426846	[]	[]	2	hSpCas9	negative selection	3455447
182585723	182585746	1	+	26780180	HT29	viability (Avana library 4 designs)	TGAGTTTGCCAATCATAGGGCGG	RNASEL	ENSG00000135828	0.755051489261321	[]	[]	3	hSpCas9	negative selection	3455448
182586498	182586521	1	-	26780180	HT29	viability (Avana library 4 designs)	TTATCCTCGCAGCGATTGCGGGG	RNASEL	ENSG00000135828	0.674128797247375	[]	[]	2	hSpCas9	negative selection	3455449
182586390	182586413	1	+	26780180	HT29	viability (Avana library 4 designs)	TTTGACCTTACCATACACAGCGG	RNASEL	ENSG00000135828	0.437613528447876	[]	[]	1	hSpCas9	negative selection	3455450
182586498	182586521	1	-	26780180	A375	viability (Avana lentiCRISPRv2)	TTATCCTCGCAGCGATTGCGGGG	RNASEL	ENSG00000135828	3.57326234718105	[]	[]	5	hSpCas9	negative selection	3553440
182585723	182585746	1	+	26780180	A375	viability (Avana lentiCRISPRv2)	TGAGTTTGCCAATCATAGGGCGG	RNASEL	ENSG00000135828	-0.845770764441694	[]	[]	-1	hSpCas9	negative selection	3553441
182586390	182586413	1	+	26780180	A375	viability (Avana lentiCRISPRv2)	TTTGACCTTACCATACACAGCGG	RNASEL	ENSG00000135828	-7.29710506046325	[]	[]	-6	hSpCas9	negative selection	3553442
182586090	182586113	1	-	26780180	A375	viability (Avana lentiCRISPRv2)	TCAATGTGAGGGGAGAAAGAGGG	RNASEL	ENSG00000135828	-1.27506218397153	[]	[]	-1	hSpCas9	negative selection	3553443
182585841	182585864	1	+	26780180	A375	viability (Avana lentiCRISPRv2)	AGAGAGAAGAACCTTCACAAGGG	RNASEL	ENSG00000135828	-6.13061506114413	[]	[]	-6	hSpCas9	negative selection	3553444
182586104	182586127	1	+	26780180	A375	viability (Avana lentiCRISPRv2)	TCACATTGACATCAGCCCCATGG	RNASEL	ENSG00000135828	-1.07325839719332	[]	[]	-1	hSpCas9	negative selection	3553445
182586498	182586521	1	-	26780180	A375	viability (Avana lentiGuide)	TTATCCTCGCAGCGATTGCGGGG	RNASEL	ENSG00000135828	1.60121760728975	[]	[]	1	hSpCas9	negative selection	3662099
182585723	182585746	1	+	26780180	A375	viability (Avana lentiGuide)	TGAGTTTGCCAATCATAGGGCGG	RNASEL	ENSG00000135828	1.93033316663812	[]	[]	2	hSpCas9	negative selection	3662100
182586390	182586413	1	+	26780180	A375	viability (Avana lentiGuide)	TTTGACCTTACCATACACAGCGG	RNASEL	ENSG00000135828	4.27253706097052	[]	[]	4	hSpCas9	negative selection	3662101
182586090	182586113	1	-	26780180	A375	viability (Avana lentiGuide)	TCAATGTGAGGGGAGAAAGAGGG	RNASEL	ENSG00000135828	-2.79275025992486	[]	[]	-5	hSpCas9	negative selection	3662102
182585841	182585864	1	+	26780180	A375	viability (Avana lentiGuide)	AGAGAGAAGAACCTTCACAAGGG	RNASEL	ENSG00000135828	2.34471729962676	[]	[]	2	hSpCas9	negative selection	3662103
182586104	182586127	1	+	26780180	A375	viability (Avana lentiGuide)	TCACATTGACATCAGCCCCATGG	RNASEL	ENSG00000135828	3.16803121599211	[]	[]	3	hSpCas9	negative selection	3662104
182586498	182586521	1	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TTATCCTCGCAGCGATTGCGGGG	RNASEL	ENSG00000135828	0.08195214050640519	[5]	[5,5]	2	hSpCas9	positive selection	3770706
182585723	182585746	1	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TGAGTTTGCCAATCATAGGGCGG	RNASEL	ENSG00000135828	-0.20112452692295024	[5]	[4,3]	-3	hSpCas9	positive selection	3770707
182586390	182586413	1	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TTTGACCTTACCATACACAGCGG	RNASEL	ENSG00000135828	-0.5597132970477885	[5]	[3,3]	-7	hSpCas9	positive selection	3770708
182586090	182586113	1	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TCAATGTGAGGGGAGAAAGAGGG	RNASEL	ENSG00000135828	0.0316871885031835	[6]	[6,5]	0	hSpCas9	positive selection	3770709
182585841	182585864	1	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AGAGAGAAGAACCTTCACAAGGG	RNASEL	ENSG00000135828	-0.5833217348831268	[6]	[4,3]	-7	hSpCas9	positive selection	3770710
182586104	182586127	1	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TCACATTGACATCAGCCCCATGG	RNASEL	ENSG00000135828	-0.15497265742277724	[4]	[3,4]	-3	hSpCas9	positive selection	3770711
182586498	182586521	1	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TTATCCTCGCAGCGATTGCGGGG	RNASEL	ENSG00000135828	-0.31894478123797726	[5]	[2,4]	-4	hSpCas9	positive selection	3879313
182585723	182585746	1	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TGAGTTTGCCAATCATAGGGCGG	RNASEL	ENSG00000135828	-0.08950527491697445	[5]	[5,3]	-1	hSpCas9	positive selection	3879314
182586390	182586413	1	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TTTGACCTTACCATACACAGCGG	RNASEL	ENSG00000135828	0.017420146808655335	[6]	[5,4]	0	hSpCas9	positive selection	3879315
182586090	182586113	1	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TCAATGTGAGGGGAGAAAGAGGG	RNASEL	ENSG00000135828	0.32447214216023024	[6]	[6,6]	8	hSpCas9	positive selection	3879316
182585841	182585864	1	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AGAGAGAAGAACCTTCACAAGGG	RNASEL	ENSG00000135828	0.1197957636216401	[5]	[4,5]	2	hSpCas9	positive selection	3879317
182586104	182586127	1	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TCACATTGACATCAGCCCCATGG	RNASEL	ENSG00000135828	-0.01034084439817734	[5]	[5,3]	0	hSpCas9	positive selection	3879318
182582116	182582139	1	-	26780180	A375	viability	ATTCATCGTCTCTTCCATCCTGG	RNASEL	ENSG00000135828	0.973068706566763	[]	[]	4	hSpCas9	negative selection	3989432
182581335	182581358	1	+	26780180	A375	viability	CATTCCGAAGCGTCCTATAGCGG	RNASEL	ENSG00000135828	0.716828263655451	[]	[]	2	hSpCas9	negative selection	3989433
182576308	182576331	1	+	26780180	A375	viability	GCAGATCACCCACAGTGTTCTGG	RNASEL	ENSG00000135828	0.679984461793906	[]	[]	2	hSpCas9	negative selection	3989434
182582081	182582104	1	-	26780180	A375	viability	GGACTGTCTGAGTGACCTGCTGG	RNASEL	ENSG00000135828	2.00932527814629	[]	[]	9	hSpCas9	negative selection	3989435
182581339	182581362	1	-	26780180	A375	viability	TCAGCCGCTATAGGACGCTTCGG	RNASEL	ENSG00000135828	0.690098421289368	[]	[]	2	hSpCas9	negative selection	3989436
182584125	182584148	1	+	26780180	A375	viability	TGCTCTTATCAAAATCTGCCAGG	RNASEL	ENSG00000135828	1.16353121600172	[]	[]	6	hSpCas9	negative selection	3989437
182582116	182582139	1	-	26780180	HT29	viability (GeCKOv2 library)	ATTCATCGTCTCTTCCATCCTGG	RNASEL	ENSG00000135828	1.00962206975106	[]	[]	4	hSpCas9	negative selection	4097398
182581335	182581358	1	+	26780180	HT29	viability (GeCKOv2 library)	CATTCCGAAGCGTCCTATAGCGG	RNASEL	ENSG00000135828	0.292823640410042	[]	[]	0	hSpCas9	negative selection	4097399
182576308	182576331	1	+	26780180	HT29	viability (GeCKOv2 library)	GCAGATCACCCACAGTGTTCTGG	RNASEL	ENSG00000135828	1.14196634885075	[]	[]	5	hSpCas9	negative selection	4097400
182582081	182582104	1	-	26780180	HT29	viability (GeCKOv2 library)	GGACTGTCTGAGTGACCTGCTGG	RNASEL	ENSG00000135828	1.922226913302	[]	[]	9	hSpCas9	negative selection	4097401
182581339	182581362	1	-	26780180	HT29	viability (GeCKOv2 library)	TCAGCCGCTATAGGACGCTTCGG	RNASEL	ENSG00000135828	0.715200099535156	[]	[]	2	hSpCas9	negative selection	4097402
182584125	182584148	1	+	26780180	HT29	viability (GeCKOv2 library)	TGCTCTTATCAAAATCTGCCAGG	RNASEL	ENSG00000135828	1.61420712555843	[]	[]	8	hSpCas9	negative selection	4097403
182582116	182582139	1	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	ATTCATCGTCTCTTCCATCCTGG	RNASEL	ENSG00000135828	0.26320747429109287	[4]	[3,4]	6	hSpCas9	positive selection	4166660
182582153	182582176	1	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GGTTCAACTTTCTCCAGATGAGG	RNASEL	ENSG00000135828	0.01927994981504777	[2]	[1,1]	0	hSpCas9	positive selection	4166661
182582058	182582081	1	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GTCATCCCTTCTTTTGGACTTGG	RNASEL	ENSG00000135828	0.1570833219087152	[3]	[2,2]	4	hSpCas9	positive selection	4166663
182584125	182584148	1	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TGCTCTTATCAAAATCTGCCAGG	RNASEL	ENSG00000135828	-0.38074644527396256	[2]	[1,0]	-7	hSpCas9	positive selection	4166664
182582116	182582139	1	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	ATTCATCGTCTCTTCCATCCTGG	RNASEL	ENSG00000135828	0.8045293699151981	[4]	[0,4,3,3]	5	hSpCas9	positive selection	4230682
182582153	182582176	1	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GGTTCAACTTTCTCCAGATGAGG	RNASEL	ENSG00000135828	-0.1468725043317608	[1]	[0,0,0,0]	-2	hSpCas9	positive selection	4230683
182582058	182582081	1	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GTCATCCCTTCTTTTGGACTTGG	RNASEL	ENSG00000135828	0.3796663209892045	[3]	[4,2,2,0]	3	hSpCas9	positive selection	4230685
182584125	182584148	1	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TGCTCTTATCAAAATCTGCCAGG	RNASEL	ENSG00000135828	0.0010619517514688648	[4]	[0,4,2,0]	0	hSpCas9	positive selection	4230686
182581339	182581362	1	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TCAGCCGCTATAGGACGCTTCGG	RNASEL	ENSG00000135828	-0.3477154668811675	[3]	[2,1]	-6	hSpCas9	positive selection	4295070
182581335	182581358	1	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CATTCCGAAGCGTCCTATAGCGG	RNASEL	ENSG00000135828	-0.5459147726484702	[1]	[0,0]	-8	hSpCas9	positive selection	4295071
182582116	182582139	1	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ATTCATCGTCTCTTCCATCCTGG	RNASEL	ENSG00000135828	0.2850461917719424	[4]	[4,3]	6	hSpCas9	positive selection	4295072
182582081	182582104	1	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GGACTGTCTGAGTGACCTGCTGG	RNASEL	ENSG00000135828	-0.4667256384520425	[3]	[2,0]	-7	hSpCas9	positive selection	4359324
182584125	182584148	1	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TGCTCTTATCAAAATCTGCCAGG	RNASEL	ENSG00000135828	0.34358833526671445	[3]	[3,3]	7	hSpCas9	positive selection	4359325
182576308	182576331	1	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GCAGATCACCCACAGTGTTCTGG	RNASEL	ENSG00000135828	-0.6682564277428553	[1]	[0,0]	-9	hSpCas9	positive selection	4359326
182586128	182586150	1	-	27760321	OCIAML3	viability	GCTATTACGCATCTGCTGCTGG	RNASEL	ENSG00000135828	0.45956184998000876	[617,607]	[650,673]	5	hSpCas9	negative selection	4434948
182586156	182586178	1	+	27760321	OCIAML3	viability	ATCACTATCGTCAGAGCTCAGG	RNASEL	ENSG00000135828	-0.760531211611633	[556,434]	[216,240]	-6	hSpCas9	negative selection	4434949
182586203	182586225	1	-	27760321	OCIAML3	viability	GTAAACGCCTGTGACAATATGG	RNASEL	ENSG00000135828	0.33037173941348147	[288,255]	[204,348]	4	hSpCas9	negative selection	4434950
182586508	182586530	1	+	27760321	OCIAML3	viability	GCTGCGAGGATAAAAGGCGTGG	RNASEL	ENSG00000135828	0.4660746796609795	[510,389]	[488,474]	5	hSpCas9	negative selection	4434951
182586602	182586624	1	+	27760321	OCIAML3	viability	TTTGTACTGCGTTATGCAGAGG	RNASEL	ENSG00000135828	-0.6431996412954776	[246,224]	[108,129]	-6	hSpCas9	negative selection	4434952
182586128	182586150	1	-	27760321	OCIAML2	viability	GCTATTACGCATCTGCTGCTGG	RNASEL	ENSG00000135828	0.6715271852342266	[617,607]	[576,1074]	8	hSpCas9	negative selection	4518411
182586156	182586178	1	+	27760321	OCIAML2	viability	ATCACTATCGTCAGAGCTCAGG	RNASEL	ENSG00000135828	-0.19803430761978782	[556,434]	[330,368]	-2	hSpCas9	negative selection	4518412
182586203	182586225	1	-	27760321	OCIAML2	viability	GTAAACGCCTGTGACAATATGG	RNASEL	ENSG00000135828	-0.1716096645265841	[288,255]	[200,187]	-2	hSpCas9	negative selection	4518413
182586508	182586530	1	+	27760321	OCIAML2	viability	GCTGCGAGGATAAAAGGCGTGG	RNASEL	ENSG00000135828	0.19532704052362293	[510,389]	[448,367]	2	hSpCas9	negative selection	4518414
182586602	182586624	1	+	27760321	OCIAML2	viability	TTTGTACTGCGTTATGCAGAGG	RNASEL	ENSG00000135828	0.3096269301442588	[246,224]	[185,302]	4	hSpCas9	negative selection	4518415
182586128	182586150	1	-	27760321	MV411	viability	GCTATTACGCATCTGCTGCTGG	RNASEL	ENSG00000135828	0.2923795413194768	[617,607]	[367,689]	2	hSpCas9	negative selection	4601874
182586156	182586178	1	+	27760321	MV411	viability	ATCACTATCGTCAGAGCTCAGG	RNASEL	ENSG00000135828	-0.09424508120898073	[556,434]	[212,441]	0	hSpCas9	negative selection	4601875
182586203	182586225	1	-	27760321	MV411	viability	GTAAACGCCTGTGACAATATGG	RNASEL	ENSG00000135828	-0.9832572642727805	[288,255]	[99,76]	-6	hSpCas9	negative selection	4601876
182586508	182586530	1	+	27760321	MV411	viability	GCTGCGAGGATAAAAGGCGTGG	RNASEL	ENSG00000135828	1.1851639528782678	[510,389]	[866,375]	8	hSpCas9	negative selection	4601877
182586602	182586624	1	+	27760321	MV411	viability	TTTGTACTGCGTTATGCAGAGG	RNASEL	ENSG00000135828	-1.6863943734454967	[246,224]	[1,117]	-8	hSpCas9	negative selection	4601878
182586128	182586150	1	-	27760321	HL60	viability	GCTATTACGCATCTGCTGCTGG	RNASEL	ENSG00000135828	0.8788250675614908	[617,607]	[946,897]	8	hSpCas9	negative selection	4685337
182586156	182586178	1	+	27760321	HL60	viability	ATCACTATCGTCAGAGCTCAGG	RNASEL	ENSG00000135828	0.3520043635466524	[556,434]	[566,456]	4	hSpCas9	negative selection	4685338
182586203	182586225	1	-	27760321	HL60	viability	GTAAACGCCTGTGACAATATGG	RNASEL	ENSG00000135828	-0.17308199204897967	[288,255]	[216,175]	-2	hSpCas9	negative selection	4685339
182586508	182586530	1	+	27760321	HL60	viability	GCTGCGAGGATAAAAGGCGTGG	RNASEL	ENSG00000135828	-0.47698515032821587	[510,389]	[240,284]	-5	hSpCas9	negative selection	4685340
182586602	182586624	1	+	27760321	HL60	viability	TTTGTACTGCGTTATGCAGAGG	RNASEL	ENSG00000135828	1.3278377145191194	[246,224]	[389,582]	9	hSpCas9	negative selection	4685341
182586128	182586150	1	-	27760321	HT1080	viability	GCTATTACGCATCTGCTGCTGG	RNASEL	ENSG00000135828	0.4206345968300508	[607,474]	[230,351]	2	hSpCas9	negative selection	4768800
182586156	182586178	1	+	27760321	HT1080	viability	ATCACTATCGTCAGAGCTCAGG	RNASEL	ENSG00000135828	1.5447099751491284	[434,339]	[479,417]	8	hSpCas9	negative selection	4768801
182586203	182586225	1	-	27760321	HT1080	viability	GTAAACGCCTGTGACAATATGG	RNASEL	ENSG00000135828	1.0217009502931906	[255,199]	[245,116]	5	hSpCas9	negative selection	4768802
182586508	182586530	1	+	27760321	HT1080	viability	GCTGCGAGGATAAAAGGCGTGG	RNASEL	ENSG00000135828	0.7487934996522939	[389,304]	[140,332]	4	hSpCas9	negative selection	4768803
182586602	182586624	1	+	27760321	HT1080	viability	TTTGTACTGCGTTATGCAGAGG	RNASEL	ENSG00000135828	0.963560621032667	[224,175]	[87,229]	5	hSpCas9	negative selection	4768804
182586128	182586150	1	-	27760321	HT29	viability after 7 days	GCTATTACGCATCTGCTGCTGG	RNASEL	ENSG00000135828	0.27189033332137413	[607,474]	[804,880,829]	4	hSpCas9	negative selection	4852263
182586156	182586178	1	+	27760321	HT29	viability after 7 days	ATCACTATCGTCAGAGCTCAGG	RNASEL	ENSG00000135828	-0.13714742857586112	[434,339]	[350,475,514]	-2	hSpCas9	negative selection	4852264
182586203	182586225	1	-	27760321	HT29	viability after 7 days	GTAAACGCCTGTGACAATATGG	RNASEL	ENSG00000135828	-0.12618471799563813	[255,199]	[264,241,296]	-2	hSpCas9	negative selection	4852265
182586508	182586530	1	+	27760321	HT29	viability after 7 days	GCTGCGAGGATAAAAGGCGTGG	RNASEL	ENSG00000135828	0.388043586426914	[389,304]	[717,520,534]	6	hSpCas9	negative selection	4852266
182586602	182586624	1	+	27760321	HT29	viability after 7 days	TTTGTACTGCGTTATGCAGAGG	RNASEL	ENSG00000135828	-1.6702474178993283	[224,175]	[57,48,130]	-9	hSpCas9	negative selection	4852267
182586128	182586150	1	-	27760321	HT29	viability after 25 days	GCTATTACGCATCTGCTGCTGG	RNASEL	ENSG00000135828	0.05258011615252833	[607,474]	[517,680,743]	0	hSpCas9	negative selection	4935726
182586156	182586178	1	+	27760321	HT29	viability after 25 days	ATCACTATCGTCAGAGCTCAGG	RNASEL	ENSG00000135828	0.38245791243012056	[434,339]	[619,482,630]	4	hSpCas9	negative selection	4935727
182586203	182586225	1	-	27760321	HT29	viability after 25 days	GTAAACGCCTGTGACAATATGG	RNASEL	ENSG00000135828	0.30091974614601563	[255,199]	[310,306,347]	3	hSpCas9	negative selection	4935728
182586508	182586530	1	+	27760321	HT29	viability after 25 days	GCTGCGAGGATAAAAGGCGTGG	RNASEL	ENSG00000135828	0.4341406879407196	[389,304]	[486,667,447]	5	hSpCas9	negative selection	4935729
182586602	182586624	1	+	27760321	HT29	viability after 25 days	TTTGTACTGCGTTATGCAGAGG	RNASEL	ENSG00000135828	-1.3350739614934328	[224,175]	[82,71,120]	-7	hSpCas9	negative selection	4935730
182586128	182586150	1	-	27760321	HT29	viability after 22 days	GCTATTACGCATCTGCTGCTGG	RNASEL	ENSG00000135828	0.27336358065610467	[607,474]	[460,735,1083]	3	hSpCas9	negative selection	5019189
182586156	182586178	1	+	27760321	HT29	viability after 22 days	ATCACTATCGTCAGAGCTCAGG	RNASEL	ENSG00000135828	0.6966294637173861	[434,339]	[988,680,498]	7	hSpCas9	negative selection	5019190
182586203	182586225	1	-	27760321	HT29	viability after 22 days	GTAAACGCCTGTGACAATATGG	RNASEL	ENSG00000135828	0.8311215270499217	[255,199]	[444,335,627]	8	hSpCas9	negative selection	5019191
182586508	182586530	1	+	27760321	HT29	viability after 22 days	GCTGCGAGGATAAAAGGCGTGG	RNASEL	ENSG00000135828	0.21650360224823534	[389,304]	[464,627,305]	2	hSpCas9	negative selection	5019192
182586602	182586624	1	+	27760321	HT29	viability after 22 days	TTTGTACTGCGTTATGCAGAGG	RNASEL	ENSG00000135828	-0.49812892248764784	[224,175]	[112,88,292]	-4	hSpCas9	negative selection	5019193
182586128	182586150	1	-	27760321	HT29	viability after 19 days	GCTATTACGCATCTGCTGCTGG	RNASEL	ENSG00000135828	0.26595402563156334	[607,474]	[792,762,684]	2	hSpCas9	negative selection	5102652
182586156	182586178	1	+	27760321	HT29	viability after 19 days	ATCACTATCGTCAGAGCTCAGG	RNASEL	ENSG00000135828	0.8737637763291969	[434,339]	[828,750,855]	8	hSpCas9	negative selection	5102653
182586203	182586225	1	-	27760321	HT29	viability after 19 days	GTAAACGCCTGTGACAATATGG	RNASEL	ENSG00000135828	0.35111681874050976	[255,199]	[386,300,315]	3	hSpCas9	negative selection	5102654
182586508	182586530	1	+	27760321	HT29	viability after 19 days	GCTGCGAGGATAAAAGGCGTGG	RNASEL	ENSG00000135828	0.66194350445917	[389,304]	[899,743,283]	6	hSpCas9	negative selection	5102655
182586602	182586624	1	+	27760321	HT29	viability after 19 days	TTTGTACTGCGTTATGCAGAGG	RNASEL	ENSG00000135828	-0.5729131326851921	[224,175]	[96,139,216]	-5	hSpCas9	negative selection	5102656
182586128	182586150	1	-	27760321	HT29	viability after 16 days	GCTATTACGCATCTGCTGCTGG	RNASEL	ENSG00000135828	0.18005640288415325	[607,474]	[714,640,706]	2	hSpCas9	negative selection	5186115
182586156	182586178	1	+	27760321	HT29	viability after 16 days	ATCACTATCGTCAGAGCTCAGG	RNASEL	ENSG00000135828	0.4710199541635906	[434,339]	[626,611,565]	5	hSpCas9	negative selection	5186116
182586203	182586225	1	-	27760321	HT29	viability after 16 days	GTAAACGCCTGTGACAATATGG	RNASEL	ENSG00000135828	0.020170552076381743	[255,199]	[232,243,296]	0	hSpCas9	negative selection	5186117
182586508	182586530	1	+	27760321	HT29	viability after 16 days	GCTGCGAGGATAAAAGGCGTGG	RNASEL	ENSG00000135828	0.8070160052411989	[389,304]	[713,908,414]	8	hSpCas9	negative selection	5186118
182586602	182586624	1	+	27760321	HT29	viability after 16 days	TTTGTACTGCGTTATGCAGAGG	RNASEL	ENSG00000135828	-0.6708964727856802	[224,175]	[133,143,143]	-6	hSpCas9	negative selection	5186119
182586128	182586150	1	-	27760321	HT29	viability after 13 days	GCTATTACGCATCTGCTGCTGG	RNASEL	ENSG00000135828	0.1594317150571284	[607,474]	[630,806,668]	2	hSpCas9	negative selection	5269578
182586156	182586178	1	+	27760321	HT29	viability after 13 days	ATCACTATCGTCAGAGCTCAGG	RNASEL	ENSG00000135828	0.2834756096821475	[434,339]	[602,433,600]	3	hSpCas9	negative selection	5269579
182586203	182586225	1	-	27760321	HT29	viability after 13 days	GTAAACGCCTGTGACAATATGG	RNASEL	ENSG00000135828	0.07658805048964745	[255,199]	[187,267,374]	0	hSpCas9	negative selection	5269580
182586508	182586530	1	+	27760321	HT29	viability after 13 days	GCTGCGAGGATAAAAGGCGTGG	RNASEL	ENSG00000135828	0.7262869133112108	[389,304]	[984,838,204]	8	hSpCas9	negative selection	5269581
182586602	182586624	1	+	27760321	HT29	viability after 13 days	TTTGTACTGCGTTATGCAGAGG	RNASEL	ENSG00000135828	-0.10093308636614684	[224,175]	[298,159,192]	-1	hSpCas9	negative selection	5269582
182586128	182586150	1	-	27760321	HT29	viability after 10 days	GCTATTACGCATCTGCTGCTGG	RNASEL	ENSG00000135828	-0.062145044880635325	[607,474]	[696,629,615]	-1	hSpCas9	negative selection	5353041
182586156	182586178	1	+	27760321	HT29	viability after 10 days	ATCACTATCGTCAGAGCTCAGG	RNASEL	ENSG00000135828	-0.09720129871501672	[434,339]	[623,356,374]	-1	hSpCas9	negative selection	5353042
182586203	182586225	1	-	27760321	HT29	viability after 10 days	GTAAACGCCTGTGACAATATGG	RNASEL	ENSG00000135828	0.13965745491448334	[255,199]	[344,242,349]	1	hSpCas9	negative selection	5353043
182586508	182586530	1	+	27760321	HT29	viability after 10 days	GCTGCGAGGATAAAAGGCGTGG	RNASEL	ENSG00000135828	-0.4379787232206021	[389,304]	[433,351,178]	-5	hSpCas9	negative selection	5353044
182586602	182586624	1	+	27760321	HT29	viability after 10 days	TTTGTACTGCGTTATGCAGAGG	RNASEL	ENSG00000135828	0.019320916802300414	[224,175]	[141,379,242]	0	hSpCas9	negative selection	5353045
182586128	182586150	1	-	27760321	MOLM13	viability	GCTATTACGCATCTGCTGCTGG	RNASEL	ENSG00000135828	1.5663892157106838	[617,607]	[1161,911]	9	hSpCas9	negative selection	5436504
182586156	182586178	1	+	27760321	MOLM13	viability	ATCACTATCGTCAGAGCTCAGG	RNASEL	ENSG00000135828	0.3331070394272249	[556,434]	[213,465]	2	hSpCas9	negative selection	5436505
182586203	182586225	1	-	27760321	MOLM13	viability	GTAAACGCCTGTGACAATATGG	RNASEL	ENSG00000135828	0.5293647031854924	[288,255]	[348,112]	3	hSpCas9	negative selection	5436506
182586508	182586530	1	+	27760321	MOLM13	viability	GCTGCGAGGATAAAAGGCGTGG	RNASEL	ENSG00000135828	1.3862941729305753	[510,389]	[816,524]	8	hSpCas9	negative selection	5436507
182586602	182586624	1	+	27760321	MOLM13	viability	TTTGTACTGCGTTATGCAGAGG	RNASEL	ENSG00000135828	-0.2135100127989703	[246,224]	[211,31]	-1	hSpCas9	negative selection	5436508
182588996	182589019	1	+	27661255	K562	viability	GAACTCTGGAAGGGCACTGGAGG	RNASEL	ENSG00000135828	0.1431310072508012	[991,1239]	[1054,916]	5	dCas9-KRAB	negative selection	5507716
182589231	182589254	1	-	27661255	K562	viability	GCAGCAGGAGGAAACTGCTCGGG	RNASEL	ENSG00000135828	-0.012637579766646145	[339,450]	[350,277]	0	dCas9-KRAB	negative selection	5507717
182581339	182581362	1	-	27260156	BXPC3	viability	TCAGCCGCTATAGGACGCTTCGG	RNASEL	ENSG00000135828	-0.030044505084635964	[623]	[670,512,462,942]	0	hSpCas9	negative selection	5567530
182581335	182581358	1	+	27260156	BXPC3	viability	CATTCCGAAGCGTCCTATAGCGG	RNASEL	ENSG00000135828	-0.30314885587934537	[107]	[94,73,83,115]	-6	hSpCas9	negative selection	5567531
182582116	182582139	1	-	27260156	BXPC3	viability	ATTCATCGTCTCTTCCATCCTGG	RNASEL	ENSG00000135828	0.15093734036397222	[1153]	[1253,1198,1439,1494]	3	hSpCas9	negative selection	5567532
182582081	182582104	1	-	27260156	BXPC3	viability	GGACTGTCTGAGTGACCTGCTGG	RNASEL	ENSG00000135828	0.06120288685588415	[598]	[604,549,711,768]	1	hSpCas9	negative selection	5631784
182584125	182584148	1	+	27260156	BXPC3	viability	TGCTCTTATCAAAATCTGCCAGG	RNASEL	ENSG00000135828	-0.23023879158171856	[802]	[706,639,751,771]	-5	hSpCas9	negative selection	5631785
182576308	182576331	1	+	27260156	BXPC3	viability	GCAGATCACCCACAGTGTTCTGG	RNASEL	ENSG00000135828	0.014728590149338805	[159]	[110,148,237,187]	0	hSpCas9	negative selection	5631786
182581339	182581362	1	-	27260156	A673	viability	TCAGCCGCTATAGGACGCTTCGG	RNASEL	ENSG00000135828	0.024457508994783828	[623]	[979,672,632,790]	0	hSpCas9	negative selection	5688781
182581335	182581358	1	+	27260156	A673	viability	CATTCCGAAGCGTCCTATAGCGG	RNASEL	ENSG00000135828	0.24777782659590541	[107]	[132,185,160,130]	6	hSpCas9	negative selection	5688782
182582116	182582139	1	-	27260156	A673	viability	ATTCATCGTCTCTTCCATCCTGG	RNASEL	ENSG00000135828	0.28743007772033713	[1153]	[1748,1640,1616,1766]	6	hSpCas9	negative selection	5688783
182582081	182582104	1	-	27260156	A673	viability	GGACTGTCTGAGTGACCTGCTGG	RNASEL	ENSG00000135828	0.11681090154177065	[598]	[879,623,863,763]	3	hSpCas9	negative selection	5753035
182584125	182584148	1	+	27260156	A673	viability	TGCTCTTATCAAAATCTGCCAGG	RNASEL	ENSG00000135828	-0.08402720531472874	[802]	[927,843,813,1063]	-2	hSpCas9	negative selection	5753036
182576308	182576331	1	+	27260156	A673	viability	GCAGATCACCCACAGTGTTCTGG	RNASEL	ENSG00000135828	0.4661359091128252	[159]	[322,226,264,252]	9	hSpCas9	negative selection	5753037
182581339	182581362	1	-	27260156	A375	viability	TCAGCCGCTATAGGACGCTTCGG	RNASEL	ENSG00000135828	-0.1551913316668112	[623]	[672,798,650,527]	-2	hSpCas9	negative selection	5810032
182581335	182581358	1	+	27260156	A375	viability	CATTCCGAAGCGTCCTATAGCGG	RNASEL	ENSG00000135828	-0.2947385175646402	[107]	[64,92,154,96]	-4	hSpCas9	negative selection	5810033
182582116	182582139	1	-	27260156	A375	viability	ATTCATCGTCTCTTCCATCCTGG	RNASEL	ENSG00000135828	0.555494525771381	[1153]	[1687,2426,2703,1245]	7	hSpCas9	negative selection	5810034
182582081	182582104	1	-	27260156	A375	viability	GGACTGTCTGAGTGACCTGCTGG	RNASEL	ENSG00000135828	0.1887261286352379	[598]	[795,701,1078,617]	2	hSpCas9	negative selection	5874286
182584125	182584148	1	+	27260156	A375	viability	TGCTCTTATCAAAATCTGCCAGG	RNASEL	ENSG00000135828	0.40348612074278567	[802]	[950,1498,1418,1134]	6	hSpCas9	negative selection	5874287
182576308	182576331	1	+	27260156	A375	viability	GCAGATCACCCACAGTGTTCTGG	RNASEL	ENSG00000135828	-0.24385681173337903	[159]	[183,167,193,93]	-4	hSpCas9	negative selection	5874288
182581339	182581362	1	-	27260156	COLO741	viability	TCAGCCGCTATAGGACGCTTCGG	RNASEL	ENSG00000135828	-0.016431136944061786	[623]	[793,871,703]	0	hSpCas9	negative selection	5931283
182581335	182581358	1	+	27260156	COLO741	viability	CATTCCGAAGCGTCCTATAGCGG	RNASEL	ENSG00000135828	-0.2843257412688218	[107]	[61,181,92]	-6	hSpCas9	negative selection	5931284
182582116	182582139	1	-	27260156	COLO741	viability	ATTCATCGTCTCTTCCATCCTGG	RNASEL	ENSG00000135828	0.3805327052292613	[1153]	[2151,1904,1730]	7	hSpCas9	negative selection	5931285
182582081	182582104	1	-	27260156	COLO741	viability	GGACTGTCTGAGTGACCTGCTGG	RNASEL	ENSG00000135828	0.22614973735527183	[598]	[1160,876,683]	5	hSpCas9	negative selection	5995537
182584125	182584148	1	+	27260156	COLO741	viability	TGCTCTTATCAAAATCTGCCAGG	RNASEL	ENSG00000135828	0.08240406096696185	[802]	[1177,970,1112]	1	hSpCas9	negative selection	5995538
182576308	182576331	1	+	27260156	COLO741	viability	GCAGATCACCCACAGTGTTCTGG	RNASEL	ENSG00000135828	0.6451257791984388	[159]	[376,152,424]	9	hSpCas9	negative selection	5995539
182581339	182581362	1	-	27260156	CAL120	viability	TCAGCCGCTATAGGACGCTTCGG	RNASEL	ENSG00000135828	-0.2059375206705562	[623]	[541,918,540]	-3	hSpCas9	negative selection	6052534
182581335	182581358	1	+	27260156	CAL120	viability	CATTCCGAAGCGTCCTATAGCGG	RNASEL	ENSG00000135828	-0.396343596970572	[107]	[228,28,67]	-5	hSpCas9	negative selection	6052535
182582116	182582139	1	-	27260156	CAL120	viability	ATTCATCGTCTCTTCCATCCTGG	RNASEL	ENSG00000135828	0.5868508996581487	[1153]	[2139,2609,1724]	8	hSpCas9	negative selection	6052536
182582081	182582104	1	-	27260156	CAL120	viability	GGACTGTCTGAGTGACCTGCTGG	RNASEL	ENSG00000135828	0.29747761721523475	[598]	[613,1093,992]	4	hSpCas9	negative selection	6116788
182584125	182584148	1	+	27260156	CAL120	viability	TGCTCTTATCAAAATCTGCCAGG	RNASEL	ENSG00000135828	0.4372745553920051	[802]	[1599,1161,1333]	6	hSpCas9	negative selection	6116789
182576308	182576331	1	+	27260156	CAL120	viability	GCAGATCACCCACAGTGTTCTGG	RNASEL	ENSG00000135828	0.08844489114100273	[159]	[192,217,220]	1	hSpCas9	negative selection	6116790
182581339	182581362	1	-	27260156	CADOES1	viability	TCAGCCGCTATAGGACGCTTCGG	RNASEL	ENSG00000135828	-0.20786470894091755	[623]	[619,427,394,568]	-4	hSpCas9	negative selection	6173785
182581335	182581358	1	+	27260156	CADOES1	viability	CATTCCGAAGCGTCCTATAGCGG	RNASEL	ENSG00000135828	-0.4146967883010544	[107]	[75,116,45,61]	-6	hSpCas9	negative selection	6173786
182582116	182582139	1	-	27260156	CADOES1	viability	ATTCATCGTCTCTTCCATCCTGG	RNASEL	ENSG00000135828	0.42730794194988997	[1153]	[1247,1359,1297,1883]	7	hSpCas9	negative selection	6173787
182582081	182582104	1	-	27260156	CADOES1	viability	GGACTGTCTGAGTGACCTGCTGG	RNASEL	ENSG00000135828	0.43852203242686255	[598]	[629,738,774,880]	7	hSpCas9	negative selection	6238039
182584125	182584148	1	+	27260156	CADOES1	viability	TGCTCTTATCAAAATCTGCCAGG	RNASEL	ENSG00000135828	0.23069076744013517	[802]	[859,769,772,1110]	4	hSpCas9	negative selection	6238040
182576308	182576331	1	+	27260156	CADOES1	viability	GCAGATCACCCACAGTGTTCTGG	RNASEL	ENSG00000135828	-0.055522015973453964	[159]	[140,171,86,173]	-1	hSpCas9	negative selection	6238041
182581339	182581362	1	-	27260156	EWS502	viability	TCAGCCGCTATAGGACGCTTCGG	RNASEL	ENSG00000135828	0.03849546375482543	[623]	[513,689,891,635]	0	hSpCas9	negative selection	6295036
182581335	182581358	1	+	27260156	EWS502	viability	CATTCCGAAGCGTCCTATAGCGG	RNASEL	ENSG00000135828	-0.2884636861172969	[107]	[98,40,101,136]	-5	hSpCas9	negative selection	6295037
182582116	182582139	1	-	27260156	EWS502	viability	ATTCATCGTCTCTTCCATCCTGG	RNASEL	ENSG00000135828	0.4250715557456324	[1153]	[1424,1817,1528,1815]	7	hSpCas9	negative selection	6295038
182582081	182582104	1	-	27260156	EWS502	viability	GGACTGTCTGAGTGACCTGCTGG	RNASEL	ENSG00000135828	0.32097146898125367	[598]	[840,877,621,815]	5	hSpCas9	negative selection	6359290
182584125	182584148	1	+	27260156	EWS502	viability	TGCTCTTATCAAAATCTGCCAGG	RNASEL	ENSG00000135828	-0.20027216311654195	[802]	[737,800,597,822]	-4	hSpCas9	negative selection	6359291
182576308	182576331	1	+	27260156	EWS502	viability	GCAGATCACCCACAGTGTTCTGG	RNASEL	ENSG00000135828	-0.12272137376454761	[159]	[147,176,202,89]	-2	hSpCas9	negative selection	6359292
182581339	182581362	1	-	27260156	EW8	viability	TCAGCCGCTATAGGACGCTTCGG	RNASEL	ENSG00000135828	0.09211403489340081	[623]	[659,549,504,458]	1	hSpCas9	negative selection	6416287
182581335	182581358	1	+	27260156	EW8	viability	CATTCCGAAGCGTCCTATAGCGG	RNASEL	ENSG00000135828	-0.1577890649805962	[107]	[47,90,43,132]	-3	hSpCas9	negative selection	6416288
182582116	182582139	1	-	27260156	EW8	viability	ATTCATCGTCTCTTCCATCCTGG	RNASEL	ENSG00000135828	0.3704505427688718	[1153]	[1537,1296,946,1131]	6	hSpCas9	negative selection	6416289
182582081	182582104	1	-	27260156	EW8	viability	GGACTGTCTGAGTGACCTGCTGG	RNASEL	ENSG00000135828	0.29559455635022897	[598]	[685,655,470,599]	5	hSpCas9	negative selection	6480541
182584125	182584148	1	+	27260156	EW8	viability	TGCTCTTATCAAAATCTGCCAGG	RNASEL	ENSG00000135828	0.29436560968370207	[802]	[813,1092,599,719]	5	hSpCas9	negative selection	6480542
182576308	182576331	1	+	27260156	EW8	viability	GCAGATCACCCACAGTGTTCTGG	RNASEL	ENSG00000135828	0.07244556987144679	[159]	[188,138,87,142]	1	hSpCas9	negative selection	6480543
182581339	182581362	1	-	27260156	CORL105	viability	TCAGCCGCTATAGGACGCTTCGG	RNASEL	ENSG00000135828	0.14542212419222827	[623]	[820,717,685,988]	2	hSpCas9	negative selection	6537538
182581335	182581358	1	+	27260156	CORL105	viability	CATTCCGAAGCGTCCTATAGCGG	RNASEL	ENSG00000135828	-0.35854951017683145	[107]	[139,107,86,58]	-6	hSpCas9	negative selection	6537539
182582116	182582139	1	-	27260156	CORL105	viability	ATTCATCGTCTCTTCCATCCTGG	RNASEL	ENSG00000135828	0.04003408196666203	[1153]	[1477,1099,1661,1366]	0	hSpCas9	negative selection	6537540
182582081	182582104	1	-	27260156	CORL105	viability	GGACTGTCTGAGTGACCTGCTGG	RNASEL	ENSG00000135828	0.33449983281019474	[598]	[1118,658,939,839]	6	hSpCas9	negative selection	6601792
182584125	182584148	1	+	27260156	CORL105	viability	TGCTCTTATCAAAATCTGCCAGG	RNASEL	ENSG00000135828	-0.174291420252915	[802]	[753,763,988,847]	-3	hSpCas9	negative selection	6601793
182576308	182576331	1	+	27260156	CORL105	viability	GCAGATCACCCACAGTGTTCTGG	RNASEL	ENSG00000135828	0.25266785438463435	[159]	[127,354,198,200]	5	hSpCas9	negative selection	6601794
182581339	182581362	1	-	27260156	HS294T	viability	TCAGCCGCTATAGGACGCTTCGG	RNASEL	ENSG00000135828	-0.30130120565612994	[623]	[184,169,225,204]	-4	hSpCas9	negative selection	6658789
182581335	182581358	1	+	27260156	HS294T	viability	CATTCCGAAGCGTCCTATAGCGG	RNASEL	ENSG00000135828	0.1418115394177708	[107]	[31,69,34,47]	2	hSpCas9	negative selection	6658790
182582116	182582139	1	-	27260156	HS294T	viability	ATTCATCGTCTCTTCCATCCTGG	RNASEL	ENSG00000135828	0.27534638544448087	[1153]	[555,521,600,465]	4	hSpCas9	negative selection	6658791
182582081	182582104	1	-	27260156	HS294T	viability	GGACTGTCTGAGTGACCTGCTGG	RNASEL	ENSG00000135828	0.5428554027419281	[598]	[410,349,221,361]	7	hSpCas9	negative selection	6723043
182584125	182584148	1	+	27260156	HS294T	viability	TGCTCTTATCAAAATCTGCCAGG	RNASEL	ENSG00000135828	0.07279825976767018	[802]	[208,349,243,549]	1	hSpCas9	negative selection	6723044
182576308	182576331	1	+	27260156	HS294T	viability	GCAGATCACCCACAGTGTTCTGG	RNASEL	ENSG00000135828	-0.24707825744981626	[159]	[53,21,46,92]	-3	hSpCas9	negative selection	6723045
182581339	182581362	1	-	27260156	HCC44	viability	TCAGCCGCTATAGGACGCTTCGG	RNASEL	ENSG00000135828	0.10878572719274254	[623]	[706,638,959,777]	1	hSpCas9	negative selection	6780040
182581335	182581358	1	+	27260156	HCC44	viability	CATTCCGAAGCGTCCTATAGCGG	RNASEL	ENSG00000135828	-0.2783742626599657	[107]	[149,45,166,63]	-4	hSpCas9	negative selection	6780041
182582116	182582139	1	-	27260156	HCC44	viability	ATTCATCGTCTCTTCCATCCTGG	RNASEL	ENSG00000135828	0.5555948778285247	[1153]	[2324,1633,2504,1389]	8	hSpCas9	negative selection	6780042
182582081	182582104	1	-	27260156	HCC44	viability	GGACTGTCTGAGTGACCTGCTGG	RNASEL	ENSG00000135828	0.17012586388900425	[598]	[784,629,1059,643]	2	hSpCas9	negative selection	6844294
182584125	182584148	1	+	27260156	HCC44	viability	TGCTCTTATCAAAATCTGCCAGG	RNASEL	ENSG00000135828	-0.020664908366446633	[802]	[1073,730,1246,630]	0	hSpCas9	negative selection	6844295
182576308	182576331	1	+	27260156	HCC44	viability	GCAGATCACCCACAGTGTTCTGG	RNASEL	ENSG00000135828	0.4141421152762004	[159]	[440,164,176,198]	6	hSpCas9	negative selection	6844296
182581339	182581362	1	-	27260156	G402	viability	TCAGCCGCTATAGGACGCTTCGG	RNASEL	ENSG00000135828	0.3046798707186344	[623]	[1200,646,1144,792]	4	hSpCas9	negative selection	6901291
182581335	182581358	1	+	27260156	G402	viability	CATTCCGAAGCGTCCTATAGCGG	RNASEL	ENSG00000135828	-0.19986492113399024	[107]	[303,45,41,90]	-3	hSpCas9	negative selection	6901292
182582116	182582139	1	-	27260156	G402	viability	ATTCATCGTCTCTTCCATCCTGG	RNASEL	ENSG00000135828	0.5198321212719537	[1153]	[3231,1871,1714,1443]	6	hSpCas9	negative selection	6901293
182582081	182582104	1	-	27260156	G402	viability	GGACTGTCTGAGTGACCTGCTGG	RNASEL	ENSG00000135828	0.12262893721833434	[598]	[745,629,883,897]	1	hSpCas9	negative selection	6965545
182584125	182584148	1	+	27260156	G402	viability	TGCTCTTATCAAAATCTGCCAGG	RNASEL	ENSG00000135828	0.3475666820616138	[802]	[1334,899,1011,1704]	4	hSpCas9	negative selection	6965546
182576308	182576331	1	+	27260156	G402	viability	GCAGATCACCCACAGTGTTCTGG	RNASEL	ENSG00000135828	-0.20101476877503255	[159]	[149,187,128,207]	-3	hSpCas9	negative selection	6965547
182581339	182581362	1	-	27260156	L33	viability	TCAGCCGCTATAGGACGCTTCGG	RNASEL	ENSG00000135828	-0.034755638522864674	[623]	[610,270,349,606]	-1	hSpCas9	negative selection	7022542
182581335	182581358	1	+	27260156	L33	viability	CATTCCGAAGCGTCCTATAGCGG	RNASEL	ENSG00000135828	-0.0002659453019981939	[107]	[116,53,60,85]	0	hSpCas9	negative selection	7022543
182582116	182582139	1	-	27260156	L33	viability	ATTCATCGTCTCTTCCATCCTGG	RNASEL	ENSG00000135828	0.17909742254409933	[1153]	[1250,561,807,1318]	4	hSpCas9	negative selection	7022544
182582081	182582104	1	-	27260156	L33	viability	GGACTGTCTGAGTGACCTGCTGG	RNASEL	ENSG00000135828	0.08376290277321341	[598]	[511,251,449,698]	1	hSpCas9	negative selection	7086796
182584125	182584148	1	+	27260156	L33	viability	TGCTCTTATCAAAATCTGCCAGG	RNASEL	ENSG00000135828	-0.14638887418155333	[802]	[650,350,429,711]	-3	hSpCas9	negative selection	7086797
182576308	182576331	1	+	27260156	L33	viability	GCAGATCACCCACAGTGTTCTGG	RNASEL	ENSG00000135828	0.14672327104558835	[159]	[158,90,88,185]	3	hSpCas9	negative selection	7086798
182581339	182581362	1	-	27260156	K562	viability	TCAGCCGCTATAGGACGCTTCGG	RNASEL	ENSG00000135828	0.02441472974273018	[623]	[436,643,398,742]	0	hSpCas9	negative selection	7143793
182581335	182581358	1	+	27260156	K562	viability	CATTCCGAAGCGTCCTATAGCGG	RNASEL	ENSG00000135828	0.44014105660187086	[107]	[124,38,112,225]	5	hSpCas9	negative selection	7143794
182582116	182582139	1	-	27260156	K562	viability	ATTCATCGTCTCTTCCATCCTGG	RNASEL	ENSG00000135828	0.26614031107169867	[1153]	[920,1115,1474,1361]	3	hSpCas9	negative selection	7143795
182582081	182582104	1	-	27260156	K562	viability	GGACTGTCTGAGTGACCTGCTGG	RNASEL	ENSG00000135828	0.2081964524978906	[598]	[508,756,707,492]	2	hSpCas9	negative selection	7208047
182584125	182584148	1	+	27260156	K562	viability	TGCTCTTATCAAAATCTGCCAGG	RNASEL	ENSG00000135828	-0.20504062221482566	[802]	[1009,469,495,528]	-3	hSpCas9	negative selection	7208048
182576308	182576331	1	+	27260156	K562	viability	GCAGATCACCCACAGTGTTCTGG	RNASEL	ENSG00000135828	0.647006636822774	[159]	[124,214,335,205]	8	hSpCas9	negative selection	7208049
182581339	182581362	1	-	27260156	HT29	viability	TCAGCCGCTATAGGACGCTTCGG	RNASEL	ENSG00000135828	-0.11755003426607313	[623]	[712,636,707,725]	-2	hSpCas9	negative selection	7265044
182581335	182581358	1	+	27260156	HT29	viability	CATTCCGAAGCGTCCTATAGCGG	RNASEL	ENSG00000135828	0.1653027222517347	[107]	[162,166,97,160]	3	hSpCas9	negative selection	7265045
182582116	182582139	1	-	27260156	HT29	viability	ATTCATCGTCTCTTCCATCCTGG	RNASEL	ENSG00000135828	0.46962079267345636	[1153]	[2065,1989,1846,1874]	8	hSpCas9	negative selection	7265046
182582081	182582104	1	-	27260156	HT29	viability	GGACTGTCTGAGTGACCTGCTGG	RNASEL	ENSG00000135828	0.3146951957612845	[598]	[884,1040,1000,721]	6	hSpCas9	negative selection	7329298
182584125	182584148	1	+	27260156	HT29	viability	TGCTCTTATCAAAATCTGCCAGG	RNASEL	ENSG00000135828	-0.056194640861244705	[802]	[996,1002,1173,623]	-1	hSpCas9	negative selection	7329299
182576308	182576331	1	+	27260156	HT29	viability	GCAGATCACCCACAGTGTTCTGG	RNASEL	ENSG00000135828	0.3693105453087413	[159]	[200,395,255,168]	7	hSpCas9	negative selection	7329300
182581339	182581362	1	-	27260156	MHHES1	viability	TCAGCCGCTATAGGACGCTTCGG	RNASEL	ENSG00000135828	-0.3463944697957848	[623]	[662,573,413,559]	-6	hSpCas9	negative selection	7386295
182581335	182581358	1	+	27260156	MHHES1	viability	CATTCCGAAGCGTCCTATAGCGG	RNASEL	ENSG00000135828	-0.07509986860139994	[107]	[93,207,90,80]	-1	hSpCas9	negative selection	7386296
182582116	182582139	1	-	27260156	MHHES1	viability	ATTCATCGTCTCTTCCATCCTGG	RNASEL	ENSG00000135828	0.6201636158657886	[1153]	[1590,3838,1743,1115]	9	hSpCas9	negative selection	7386297
182582081	182582104	1	-	27260156	MHHES1	viability	GGACTGTCTGAGTGACCTGCTGG	RNASEL	ENSG00000135828	0.12712226548941424	[598]	[816,923,661,589]	2	hSpCas9	negative selection	7450549
182584125	182584148	1	+	27260156	MHHES1	viability	TGCTCTTATCAAAATCTGCCAGG	RNASEL	ENSG00000135828	0.14454176311911815	[802]	[1325,860,1143,733]	2	hSpCas9	negative selection	7450550
182576308	182576331	1	+	27260156	MHHES1	viability	GCAGATCACCCACAGTGTTCTGG	RNASEL	ENSG00000135828	0.18774891981633823	[159]	[289,339,115,114]	3	hSpCas9	negative selection	7450551
182581339	182581362	1	-	27260156	MEWO	viability	TCAGCCGCTATAGGACGCTTCGG	RNASEL	ENSG00000135828	0.09192688611410799	[623]	[694,532,652]	2	hSpCas9	negative selection	7507546
182581335	182581358	1	+	27260156	MEWO	viability	CATTCCGAAGCGTCCTATAGCGG	RNASEL	ENSG00000135828	-0.2957414944583965	[107]	[87,86,72]	-6	hSpCas9	negative selection	7507547
182582116	182582139	1	-	27260156	MEWO	viability	ATTCATCGTCTCTTCCATCCTGG	RNASEL	ENSG00000135828	0.4133412666728713	[1153]	[1445,1589,1277]	8	hSpCas9	negative selection	7507548
182582081	182582104	1	-	27260156	MEWO	viability	GGACTGTCTGAGTGACCTGCTGG	RNASEL	ENSG00000135828	0.1854898736838379	[598]	[739,560,630]	4	hSpCas9	negative selection	7571800
182584125	182584148	1	+	27260156	MEWO	viability	TGCTCTTATCAAAATCTGCCAGG	RNASEL	ENSG00000135828	-0.18193206068760726	[802]	[869,630,525]	-4	hSpCas9	negative selection	7571801
182576308	182576331	1	+	27260156	MEWO	viability	GCAGATCACCCACAGTGTTCTGG	RNASEL	ENSG00000135828	0.1548334618025271	[159]	[187,175,139]	3	hSpCas9	negative selection	7571802
182581339	182581362	1	-	27260156	LNCAPCLONEFGC	viability	TCAGCCGCTATAGGACGCTTCGG	RNASEL	ENSG00000135828	0.09017723836246033	[623]	[542,695,686,487]	1	hSpCas9	negative selection	7628797
182581335	182581358	1	+	27260156	LNCAPCLONEFGC	viability	CATTCCGAAGCGTCCTATAGCGG	RNASEL	ENSG00000135828	-0.4832317638883201	[107]	[84,38,105,56]	-6	hSpCas9	negative selection	7628798
182582116	182582139	1	-	27260156	LNCAPCLONEFGC	viability	ATTCATCGTCTCTTCCATCCTGG	RNASEL	ENSG00000135828	0.4253777321199528	[1153]	[1246,1189,1682,1552]	6	hSpCas9	negative selection	7628799
182582081	182582104	1	-	27260156	LNCAPCLONEFGC	viability	GGACTGTCTGAGTGACCTGCTGG	RNASEL	ENSG00000135828	0.33904998004479986	[598]	[892,402,856,631]	5	hSpCas9	negative selection	7693051
182584125	182584148	1	+	27260156	LNCAPCLONEFGC	viability	TGCTCTTATCAAAATCTGCCAGG	RNASEL	ENSG00000135828	0.09173383365269339	[802]	[751,423,1052,935]	1	hSpCas9	negative selection	7693052
182576308	182576331	1	+	27260156	LNCAPCLONEFGC	viability	GCAGATCACCCACAGTGTTCTGG	RNASEL	ENSG00000135828	0.23096746268031554	[159]	[161,180,144,187]	3	hSpCas9	negative selection	7693053
182581339	182581362	1	-	27260156	PANC0327	viability	TCAGCCGCTATAGGACGCTTCGG	RNASEL	ENSG00000135828	-0.05149347531227749	[623]	[614,435,694,412]	0	hSpCas9	negative selection	7750048
182581335	182581358	1	+	27260156	PANC0327	viability	CATTCCGAAGCGTCCTATAGCGG	RNASEL	ENSG00000135828	-0.675126300736975	[107]	[158,8,41,44]	-7	hSpCas9	negative selection	7750049
182582116	182582139	1	-	27260156	PANC0327	viability	ATTCATCGTCTCTTCCATCCTGG	RNASEL	ENSG00000135828	0.3267018871573193	[1153]	[1295,1208,1357,1289]	5	hSpCas9	negative selection	7750050
182582081	182582104	1	-	27260156	PANC0327	viability	GGACTGTCTGAGTGACCTGCTGG	RNASEL	ENSG00000135828	0.5949387621571527	[598]	[871,860,897,581]	8	hSpCas9	negative selection	7814302
182584125	182584148	1	+	27260156	PANC0327	viability	TGCTCTTATCAAAATCTGCCAGG	RNASEL	ENSG00000135828	0.20335236578051785	[802]	[1088,819,746,650]	3	hSpCas9	negative selection	7814303
182576308	182576331	1	+	27260156	PANC0327	viability	GCAGATCACCCACAGTGTTCTGG	RNASEL	ENSG00000135828	0.9796409448727563	[159]	[178,223,333,382]	9	hSpCas9	negative selection	7814304
182581339	182581362	1	-	27260156	NCIH2009	viability	TCAGCCGCTATAGGACGCTTCGG	RNASEL	ENSG00000135828	-0.3128325813835855	[623]	[859,573,703]	-4	hSpCas9	negative selection	7871299
182581335	182581358	1	+	27260156	NCIH2009	viability	CATTCCGAAGCGTCCTATAGCGG	RNASEL	ENSG00000135828	0.2746814735263774	[107]	[217,199,135]	4	hSpCas9	negative selection	7871300
182582116	182582139	1	-	27260156	NCIH2009	viability	ATTCATCGTCTCTTCCATCCTGG	RNASEL	ENSG00000135828	0.2788588737338362	[1153]	[1886,1921,2042]	4	hSpCas9	negative selection	7871301
182582081	182582104	1	-	27260156	NCIH2009	viability	GGACTGTCTGAGTGACCTGCTGG	RNASEL	ENSG00000135828	0.10496534846583905	[598]	[959,926,822]	1	hSpCas9	negative selection	7935553
182584125	182584148	1	+	27260156	NCIH2009	viability	TGCTCTTATCAAAATCTGCCAGG	RNASEL	ENSG00000135828	0.0924727293042199	[802]	[1646,789,1245]	1	hSpCas9	negative selection	7935554
182576308	182576331	1	+	27260156	NCIH2009	viability	GCAGATCACCCACAGTGTTCTGG	RNASEL	ENSG00000135828	-0.1722699887049397	[159]	[221,224,151]	-2	hSpCas9	negative selection	7935555
182581339	182581362	1	-	27260156	NCIH1373	viability	TCAGCCGCTATAGGACGCTTCGG	RNASEL	ENSG00000135828	-0.569118735531277	[623]	[424,584,456,102]	-5	hSpCas9	negative selection	7992550
182581335	182581358	1	+	27260156	NCIH1373	viability	CATTCCGAAGCGTCCTATAGCGG	RNASEL	ENSG00000135828	0.12932723858567852	[107]	[83,159,84,50]	1	hSpCas9	negative selection	7992551
182582116	182582139	1	-	27260156	NCIH1373	viability	ATTCATCGTCTCTTCCATCCTGG	RNASEL	ENSG00000135828	0.3111188756558565	[1153]	[2125,1155,1014,603]	3	hSpCas9	negative selection	7992552
182582081	182582104	1	-	27260156	NCIH1373	viability	GGACTGTCTGAGTGACCTGCTGG	RNASEL	ENSG00000135828	0.5644781695423355	[598]	[1650,916,938,142]	5	hSpCas9	negative selection	8056804
182584125	182584148	1	+	27260156	NCIH1373	viability	TGCTCTTATCAAAATCTGCCAGG	RNASEL	ENSG00000135828	0.19699593755564782	[802]	[1457,575,1088,293]	2	hSpCas9	negative selection	8056805
182576308	182576331	1	+	27260156	NCIH1373	viability	GCAGATCACCCACAGTGTTCTGG	RNASEL	ENSG00000135828	-0.8780493985918942	[159]	[86,69,60,46]	-7	hSpCas9	negative selection	8056806
182581339	182581362	1	-	27260156	PATU8902	viability	TCAGCCGCTATAGGACGCTTCGG	RNASEL	ENSG00000135828	0.011429637918624502	[623]	[908,951,719,966]	0	hSpCas9	negative selection	8113801
182581335	182581358	1	+	27260156	PATU8902	viability	CATTCCGAAGCGTCCTATAGCGG	RNASEL	ENSG00000135828	-0.5629251076465343	[107]	[109,68,132,83]	-5	hSpCas9	negative selection	8113802
182582116	182582139	1	-	27260156	PATU8902	viability	ATTCATCGTCTCTTCCATCCTGG	RNASEL	ENSG00000135828	0.17768117247787774	[1153]	[1611,1524,2117,1939]	1	hSpCas9	negative selection	8113803
182582081	182582104	1	-	27260156	PATU8902	viability	GGACTGTCTGAGTGACCTGCTGG	RNASEL	ENSG00000135828	0.5102779182881585	[598]	[1060,950,1214,1553]	5	hSpCas9	negative selection	8178055
182584125	182584148	1	+	27260156	PATU8902	viability	TGCTCTTATCAAAATCTGCCAGG	RNASEL	ENSG00000135828	-0.24871819294487285	[802]	[1128,449,931,1285]	-3	hSpCas9	negative selection	8178056
182576308	182576331	1	+	27260156	PATU8902	viability	GCAGATCACCCACAGTGTTCTGG	RNASEL	ENSG00000135828	-0.12346480117508318	[159]	[161,181,363,48]	-1	hSpCas9	negative selection	8178057
182581339	182581362	1	-	27260156	PANC1	viability	TCAGCCGCTATAGGACGCTTCGG	RNASEL	ENSG00000135828	0.1338344509258072	[623]	[556,633,643,527]	2	hSpCas9	negative selection	8235052
182581335	182581358	1	+	27260156	PANC1	viability	CATTCCGAAGCGTCCTATAGCGG	RNASEL	ENSG00000135828	0.8562426477825815	[107]	[158,233,112,174]	9	hSpCas9	negative selection	8235053
182582116	182582139	1	-	27260156	PANC1	viability	ATTCATCGTCTCTTCCATCCTGG	RNASEL	ENSG00000135828	0.5442701453443146	[1153]	[1547,1355,1418,1417]	8	hSpCas9	negative selection	8235054
182582081	182582104	1	-	27260156	PANC1	viability	GGACTGTCTGAGTGACCTGCTGG	RNASEL	ENSG00000135828	0.23510023778793881	[598]	[374,734,988,384]	4	hSpCas9	negative selection	8299306
182584125	182584148	1	+	27260156	PANC1	viability	TGCTCTTATCAAAATCTGCCAGG	RNASEL	ENSG00000135828	0.34814753249058683	[802]	[776,976,896,869]	5	hSpCas9	negative selection	8299307
182576308	182576331	1	+	27260156	PANC1	viability	GCAGATCACCCACAGTGTTCTGG	RNASEL	ENSG00000135828	0.7349896130494704	[159]	[193,403,232,132]	9	hSpCas9	negative selection	8299308
182581339	182581362	1	-	27260156	PANC0813	viability	TCAGCCGCTATAGGACGCTTCGG	RNASEL	ENSG00000135828	0.2092050331086695	[623]	[1134,879,753,655]	3	hSpCas9	negative selection	8356303
182581335	182581358	1	+	27260156	PANC0813	viability	CATTCCGAAGCGTCCTATAGCGG	RNASEL	ENSG00000135828	0.026262873954977728	[107]	[156,52,275,38]	0	hSpCas9	negative selection	8356304
182582116	182582139	1	-	27260156	PANC0813	viability	ATTCATCGTCTCTTCCATCCTGG	RNASEL	ENSG00000135828	0.36516001142104604	[1153]	[1930,1733,1752,1588]	6	hSpCas9	negative selection	8356305
182582081	182582104	1	-	27260156	PANC0813	viability	GGACTGTCTGAGTGACCTGCTGG	RNASEL	ENSG00000135828	0.3036047314774422	[598]	[835,884,926,823]	5	hSpCas9	negative selection	8420557
182584125	182584148	1	+	27260156	PANC0813	viability	TGCTCTTATCAAAATCTGCCAGG	RNASEL	ENSG00000135828	-0.28050718812991327	[802]	[1048,677,685,719]	-4	hSpCas9	negative selection	8420558
182576308	182576331	1	+	27260156	PANC0813	viability	GCAGATCACCCACAGTGTTCTGG	RNASEL	ENSG00000135828	0.08243502390079027	[159]	[180,163,142,299]	1	hSpCas9	negative selection	8420559
182581339	182581362	1	-	27260156	RDES	viability	TCAGCCGCTATAGGACGCTTCGG	RNASEL	ENSG00000135828	-0.30633240970591924	[623]	[519,471,507,867]	-5	hSpCas9	negative selection	8477554
182581335	182581358	1	+	27260156	RDES	viability	CATTCCGAAGCGTCCTATAGCGG	RNASEL	ENSG00000135828	-0.18704199893251117	[107]	[148,68,83,126]	-3	hSpCas9	negative selection	8477555
182582116	182582139	1	-	27260156	RDES	viability	ATTCATCGTCTCTTCCATCCTGG	RNASEL	ENSG00000135828	0.3317991551265216	[1153]	[1266,1636,1976,1885]	5	hSpCas9	negative selection	8477556
182582081	182582104	1	-	27260156	RDES	viability	GGACTGTCTGAGTGACCTGCTGG	RNASEL	ENSG00000135828	0.2484588782114961	[598]	[724,657,922,1010]	4	hSpCas9	negative selection	8541808
182584125	182584148	1	+	27260156	RDES	viability	TGCTCTTATCAAAATCTGCCAGG	RNASEL	ENSG00000135828	0.15765185519291558	[802]	[923,989,1088,1127]	2	hSpCas9	negative selection	8541809
182576308	182576331	1	+	27260156	RDES	viability	GCAGATCACCCACAGTGTTCTGG	RNASEL	ENSG00000135828	0.026879485009088322	[159]	[151,163,257,181]	0	hSpCas9	negative selection	8541810
182581339	182581362	1	-	27260156	PC3	viability	TCAGCCGCTATAGGACGCTTCGG	RNASEL	ENSG00000135828	0.15706874871558135	[623]	[436,637,1205,742]	3	hSpCas9	negative selection	8598805
182581335	182581358	1	+	27260156	PC3	viability	CATTCCGAAGCGTCCTATAGCGG	RNASEL	ENSG00000135828	0.6646727954418135	[107]	[99,206,185,209]	9	hSpCas9	negative selection	8598806
182582116	182582139	1	-	27260156	PC3	viability	ATTCATCGTCTCTTCCATCCTGG	RNASEL	ENSG00000135828	0.289027474090537	[1153]	[867,1316,2713,1335]	6	hSpCas9	negative selection	8598807
182582081	182582104	1	-	27260156	PC3	viability	GGACTGTCTGAGTGACCTGCTGG	RNASEL	ENSG00000135828	-0.16754999709698656	[598]	[364,514,958,468]	-4	hSpCas9	negative selection	8663059
182584125	182584148	1	+	27260156	PC3	viability	TGCTCTTATCAAAATCTGCCAGG	RNASEL	ENSG00000135828	0.007252189789917929	[802]	[645,774,1076,797]	0	hSpCas9	negative selection	8663060
182576308	182576331	1	+	27260156	PC3	viability	GCAGATCACCCACAGTGTTCTGG	RNASEL	ENSG00000135828	0.24910097473171078	[159]	[158,71,388,213]	5	hSpCas9	negative selection	8663061
182581339	182581362	1	-	27260156	PATU8988T	viability	TCAGCCGCTATAGGACGCTTCGG	RNASEL	ENSG00000135828	0.3007511720770802	[623]	[730,850,677,719]	5	hSpCas9	negative selection	8720056
182581335	182581358	1	+	27260156	PATU8988T	viability	CATTCCGAAGCGTCCTATAGCGG	RNASEL	ENSG00000135828	0.6219293853456718	[107]	[189,153,196,94]	8	hSpCas9	negative selection	8720057
182582116	182582139	1	-	27260156	PATU8988T	viability	ATTCATCGTCTCTTCCATCCTGG	RNASEL	ENSG00000135828	0.5054831322721285	[1153]	[1856,1594,1074,1832]	8	hSpCas9	negative selection	8720058
182582081	182582104	1	-	27260156	PATU8988T	viability	GGACTGTCTGAGTGACCTGCTGG	RNASEL	ENSG00000135828	0.2919486873045673	[598]	[721,639,583,898]	5	hSpCas9	negative selection	8784310
182584125	182584148	1	+	27260156	PATU8988T	viability	TGCTCTTATCAAAATCTGCCAGG	RNASEL	ENSG00000135828	-0.12884694474190106	[802]	[828,719,730,545]	-2	hSpCas9	negative selection	8784311
182576308	182576331	1	+	27260156	PATU8988T	viability	GCAGATCACCCACAGTGTTCTGG	RNASEL	ENSG00000135828	0.43598640843270675	[159]	[135,325,117,273]	7	hSpCas9	negative selection	8784312
182581339	182581362	1	-	27260156	T47D	viability	TCAGCCGCTATAGGACGCTTCGG	RNASEL	ENSG00000135828	-0.11421200860635222	[623]	[817,558,547,776]	-3	hSpCas9	negative selection	8841307
182581335	182581358	1	+	27260156	T47D	viability	CATTCCGAAGCGTCCTATAGCGG	RNASEL	ENSG00000135828	-0.2348258973806474	[107]	[87,128,95,112]	-5	hSpCas9	negative selection	8841308
182582116	182582139	1	-	27260156	T47D	viability	ATTCATCGTCTCTTCCATCCTGG	RNASEL	ENSG00000135828	0.37099889911764405	[1153]	[1713,1653,1718,1878]	7	hSpCas9	negative selection	8841309
182582081	182582104	1	-	27260156	T47D	viability	GGACTGTCTGAGTGACCTGCTGG	RNASEL	ENSG00000135828	0.1606645946475907	[598]	[825,638,797,871]	3	hSpCas9	negative selection	8905561
182584125	182584148	1	+	27260156	T47D	viability	TGCTCTTATCAAAATCTGCCAGG	RNASEL	ENSG00000135828	0.012652885401613356	[802]	[952,995,879,941]	0	hSpCas9	negative selection	8905562
182576308	182576331	1	+	27260156	T47D	viability	GCAGATCACCCACAGTGTTCTGG	RNASEL	ENSG00000135828	0.41210119259082	[159]	[280,266,201,240]	8	hSpCas9	negative selection	8905563
182581339	182581362	1	-	27260156	SU8686	viability	TCAGCCGCTATAGGACGCTTCGG	RNASEL	ENSG00000135828	0.013088678900915196	[623]	[485,644,605,795]	0	hSpCas9	negative selection	8962558
182581335	182581358	1	+	27260156	SU8686	viability	CATTCCGAAGCGTCCTATAGCGG	RNASEL	ENSG00000135828	0.35834165031370513	[107]	[108,97,142,219]	6	hSpCas9	negative selection	8962559
182582116	182582139	1	-	27260156	SU8686	viability	ATTCATCGTCTCTTCCATCCTGG	RNASEL	ENSG00000135828	0.3037232906141252	[1153]	[1159,1248,1540,1805]	5	hSpCas9	negative selection	8962560
182582081	182582104	1	-	27260156	SU8686	viability	GGACTGTCTGAGTGACCTGCTGG	RNASEL	ENSG00000135828	0.3440408669665755	[598]	[701,664,763,923]	6	hSpCas9	negative selection	9026812
182584125	182584148	1	+	27260156	SU8686	viability	TGCTCTTATCAAAATCTGCCAGG	RNASEL	ENSG00000135828	0.1317703822560763	[802]	[848,724,905,1054]	2	hSpCas9	negative selection	9026813
182576308	182576331	1	+	27260156	SU8686	viability	GCAGATCACCCACAGTGTTCTGG	RNASEL	ENSG00000135828	-0.05354773382058986	[159]	[81,180,137,224]	-1	hSpCas9	negative selection	9026814
182581339	182581362	1	-	27260156	SKES1	viability	TCAGCCGCTATAGGACGCTTCGG	RNASEL	ENSG00000135828	-0.05421218598403549	[623]	[822,661,457,500]	-1	hSpCas9	negative selection	9083809
182581335	182581358	1	+	27260156	SKES1	viability	CATTCCGAAGCGTCCTATAGCGG	RNASEL	ENSG00000135828	0.08414480056411877	[107]	[143,84,172,59]	1	hSpCas9	negative selection	9083810
182582116	182582139	1	-	27260156	SKES1	viability	ATTCATCGTCTCTTCCATCCTGG	RNASEL	ENSG00000135828	0.3448215057644881	[1153]	[1582,1502,1546,1245]	7	hSpCas9	negative selection	9083811
182582081	182582104	1	-	27260156	SKES1	viability	GGACTGTCTGAGTGACCTGCTGG	RNASEL	ENSG00000135828	0.05917389233642567	[598]	[606,681,565,632]	1	hSpCas9	negative selection	9148063
182584125	182584148	1	+	27260156	SKES1	viability	TGCTCTTATCAAAATCTGCCAGG	RNASEL	ENSG00000135828	-0.20028287722134652	[802]	[774,664,725,629]	-4	hSpCas9	negative selection	9148064
182576308	182576331	1	+	27260156	SKES1	viability	GCAGATCACCCACAGTGTTCTGG	RNASEL	ENSG00000135828	0.6028972602837439	[159]	[330,253,165,231]	9	hSpCas9	negative selection	9148065
182581339	182581362	1	-	27260156	TOV112D	viability	TCAGCCGCTATAGGACGCTTCGG	RNASEL	ENSG00000135828	0.025943740032199458	[623]	[603,1147,518,402]	0	hSpCas9	negative selection	9205060
182581335	182581358	1	+	27260156	TOV112D	viability	CATTCCGAAGCGTCCTATAGCGG	RNASEL	ENSG00000135828	-0.21197242116880544	[107]	[112,70,108,76]	-4	hSpCas9	negative selection	9205061
182582116	182582139	1	-	27260156	TOV112D	viability	ATTCATCGTCTCTTCCATCCTGG	RNASEL	ENSG00000135828	0.3680117804860872	[1153]	[1440,1819,1483,1300]	7	hSpCas9	negative selection	9205062
182582081	182582104	1	-	27260156	TOV112D	viability	GGACTGTCTGAGTGACCTGCTGG	RNASEL	ENSG00000135828	0.33973370488067084	[598]	[706,1216,536,684]	6	hSpCas9	negative selection	9269314
182584125	182584148	1	+	27260156	TOV112D	viability	TGCTCTTATCAAAATCTGCCAGG	RNASEL	ENSG00000135828	-0.08575101086884829	[802]	[770,750,984,528]	-2	hSpCas9	negative selection	9269315
182576308	182576331	1	+	27260156	TOV112D	viability	GCAGATCACCCACAGTGTTCTGG	RNASEL	ENSG00000135828	-0.5733015860178698	[159]	[128,141,139,31]	-8	hSpCas9	negative selection	9269316
182581339	182581362	1	-	27260156	TC71	viability	TCAGCCGCTATAGGACGCTTCGG	RNASEL	ENSG00000135828	-0.04084866030720352	[623]	[680,640,616,662]	-1	hSpCas9	negative selection	9326311
182581335	182581358	1	+	27260156	TC71	viability	CATTCCGAAGCGTCCTATAGCGG	RNASEL	ENSG00000135828	0.4603456994090027	[107]	[270,114,99,149]	9	hSpCas9	negative selection	9326312
182582116	182582139	1	-	27260156	TC71	viability	ATTCATCGTCTCTTCCATCCTGG	RNASEL	ENSG00000135828	0.27110468369389484	[1153]	[1503,1372,1459,1643]	6	hSpCas9	negative selection	9326313
182582081	182582104	1	-	27260156	TC71	viability	GGACTGTCTGAGTGACCTGCTGG	RNASEL	ENSG00000135828	0.1521628454564013	[598]	[781,650,742,672]	4	hSpCas9	negative selection	9390565
182584125	182584148	1	+	27260156	TC71	viability	TGCTCTTATCAAAATCTGCCAGG	RNASEL	ENSG00000135828	-0.0888524475051804	[802]	[744,844,796,854]	-2	hSpCas9	negative selection	9390566
182576308	182576331	1	+	27260156	TC71	viability	GCAGATCACCCACAGTGTTCTGG	RNASEL	ENSG00000135828	0.27018431468279136	[159]	[203,185,245,188]	6	hSpCas9	negative selection	9390567
182581339	182581362	1	-	27260156	TC32	viability	TCAGCCGCTATAGGACGCTTCGG	RNASEL	ENSG00000135828	-0.36232115001514453	[623]	[417,469,588,332]	-6	hSpCas9	negative selection	9447562
182581335	182581358	1	+	27260156	TC32	viability	CATTCCGAAGCGTCCTATAGCGG	RNASEL	ENSG00000135828	-0.15619253359128926	[107]	[153,12,124,94]	-3	hSpCas9	negative selection	9447563
182582116	182582139	1	-	27260156	TC32	viability	ATTCATCGTCTCTTCCATCCTGG	RNASEL	ENSG00000135828	0.2781395788880867	[1153]	[1321,975,1486,1566]	5	hSpCas9	negative selection	9447564
182582081	182582104	1	-	27260156	TC32	viability	GGACTGTCTGAGTGACCTGCTGG	RNASEL	ENSG00000135828	0.34905110161992076	[598]	[654,575,943,751]	6	hSpCas9	negative selection	9511816
182584125	182584148	1	+	27260156	TC32	viability	TGCTCTTATCAAAATCTGCCAGG	RNASEL	ENSG00000135828	0.04743465976326977	[802]	[611,699,1116,750]	0	hSpCas9	negative selection	9511817
182576308	182576331	1	+	27260156	TC32	viability	GCAGATCACCCACAGTGTTCTGG	RNASEL	ENSG00000135828	-0.18123153074864828	[159]	[126,141,127,119]	-3	hSpCas9	negative selection	9511818
182575382	182575405	1	+	27869803	HPAFII	viability after 27 days	AATCAGTCCATCAGCACCCAGGG	RNASEL	ENSG00000135828	-0.8158891740064493	[255]	[28,115,NaN]	-5	hSpCas9	negative selection	9530890
182582222	182582245	1	-	27869803	HPAFII	viability after 27 days	GGTCCTCTATGTGGTAAAGAAGG	RNASEL	ENSG00000135828	1.106022867498005	[115]	[85,168,NaN]	8	hSpCas9	negative selection	9530891
182582243	182582266	1	-	27869803	HPAFII	viability after 27 days	TGTGCAGGACCTTGGACGGCTGG	RNASEL	ENSG00000135828	1.3862231698396004	[256]	[482,244,NaN]	9	hSpCas9	negative selection	9530892
182584143	182584166	1	-	27869803	HPAFII	viability after 27 days	TTCTAAGAAAGCTGCTCACCTGG	RNASEL	ENSG00000135828	-1.0155303291455682	[164]	[67,21,NaN]	-6	hSpCas9	negative selection	9530893
182585525	182585548	1	-	27869803	HPAFII	viability after 27 days	CTATGGGAGTGAGAGCCACAGGG	RNASEL	ENSG00000135828	0.5116504743749926	[440]	[437,240,NaN]	4	hSpCas9	negative selection	9530894
182585526	182585549	1	-	27869803	HPAFII	viability after 27 days	TCTATGGGAGTGAGAGCCACAGG	RNASEL	ENSG00000135828	-2.518045364736563	[103]	[14,4,NaN]	-8	hSpCas9	negative selection	9530895
182575382	182575405	1	+	27869803	HPAFII	viability after 15 days	AATCAGTCCATCAGCACCCAGGG	RNASEL	ENSG00000135828	-0.4406864984242602	[255]	[153,232,NaN]	-5	hSpCas9	negative selection	9613339
182582222	182582245	1	-	27869803	HPAFII	viability after 15 days	GGTCCTCTATGTGGTAAAGAAGG	RNASEL	ENSG00000135828	0.6674270877476005	[115]	[234,174,NaN]	7	hSpCas9	negative selection	9613340
182582243	182582266	1	-	27869803	HPAFII	viability after 15 days	TGTGCAGGACCTTGGACGGCTGG	RNASEL	ENSG00000135828	1.0849405194851192	[256]	[707,509,NaN]	9	hSpCas9	negative selection	9613341
182584143	182584166	1	-	27869803	HPAFII	viability after 15 days	TTCTAAGAAAGCTGCTCACCTGG	RNASEL	ENSG00000135828	-0.06456867430058078	[164]	[192,154,NaN]	0	hSpCas9	negative selection	9613342
182585525	182585548	1	-	27869803	HPAFII	viability after 15 days	CTATGGGAGTGAGAGCCACAGGG	RNASEL	ENSG00000135828	0.43368532790950653	[440]	[596,666,NaN]	5	hSpCas9	negative selection	9613343
182585526	182585549	1	-	27869803	HPAFII	viability after 15 days	TCTATGGGAGTGAGAGCCACAGG	RNASEL	ENSG00000135828	-0.1456978685713377	[103]	[121,87,NaN]	-2	hSpCas9	negative selection	9613344
182575382	182575405	1	+	27869803	ASPC1	viability after 36 days	AATCAGTCCATCAGCACCCAGGG	RNASEL	ENSG00000135828	-0.22795756093248348	[754]	[393,102,200]	-2	hSpCas9	negative selection	9695788
182582222	182582245	1	-	27869803	ASPC1	viability after 36 days	GGTCCTCTATGTGGTAAAGAAGG	RNASEL	ENSG00000135828	-0.2211897762803836	[288]	[143,125,13]	-2	hSpCas9	negative selection	9695789
182582243	182582266	1	-	27869803	ASPC1	viability after 36 days	TGTGCAGGACCTTGGACGGCTGG	RNASEL	ENSG00000135828	-0.2849511619536218	[852]	[279,446,55]	-3	hSpCas9	negative selection	9695790
182584143	182584166	1	-	27869803	ASPC1	viability after 36 days	TTCTAAGAAAGCTGCTCACCTGG	RNASEL	ENSG00000135828	0.19370404250896966	[347]	[70,60,246]	2	hSpCas9	negative selection	9695791
182585525	182585548	1	-	27869803	ASPC1	viability after 36 days	CTATGGGAGTGAGAGCCACAGGG	RNASEL	ENSG00000135828	0.09732234492796787	[959]	[328,159,532]	0	hSpCas9	negative selection	9695792
182585526	182585549	1	-	27869803	ASPC1	viability after 36 days	TCTATGGGAGTGAGAGCCACAGG	RNASEL	ENSG00000135828	0.24851735337982728	[260]	[12,189,108]	2	hSpCas9	negative selection	9695793
182575382	182575405	1	+	27869803	PATU8988S	viability after 35 days	AATCAGTCCATCAGCACCCAGGG	RNASEL	ENSG00000135828	-0.15787005576342178	[546]	[183,210,NaN]	-2	hSpCas9	negative selection	9778237
182582222	182582245	1	-	27869803	PATU8988S	viability after 35 days	GGTCCTCTATGTGGTAAAGAAGG	RNASEL	ENSG00000135828	0.38191178168199147	[221]	[119,112,NaN]	4	hSpCas9	negative selection	9778238
182582243	182582266	1	-	27869803	PATU8988S	viability after 35 days	TGTGCAGGACCTTGGACGGCTGG	RNASEL	ENSG00000135828	-0.08595360320168169	[591]	[284,163,NaN]	-1	hSpCas9	negative selection	9778239
182584143	182584166	1	-	27869803	PATU8988S	viability after 35 days	TTCTAAGAAAGCTGCTCACCTGG	RNASEL	ENSG00000135828	0.03072804160339926	[294]	[63,178,NaN]	0	hSpCas9	negative selection	9778240
182585525	182585548	1	-	27869803	PATU8988S	viability after 35 days	CTATGGGAGTGAGAGCCACAGGG	RNASEL	ENSG00000135828	-0.3561931336207418	[864]	[342,200,NaN]	-4	hSpCas9	negative selection	9778241
182585526	182585549	1	-	27869803	PATU8988S	viability after 35 days	TCTATGGGAGTGAGAGCCACAGG	RNASEL	ENSG00000135828	0.015506368431992934	[194]	[28,129,NaN]	0	hSpCas9	negative selection	9778242
182575382	182575405	1	+	27869803	PATU8988S	viability after 31 days	AATCAGTCCATCAGCACCCAGGG	RNASEL	ENSG00000135828	0.4806002166693722	[546]	[196,440,NaN]	6	hSpCas9	negative selection	9860686
182582222	182582245	1	-	27869803	PATU8988S	viability after 31 days	GGTCCTCTATGTGGTAAAGAAGG	RNASEL	ENSG00000135828	0.29602769869211754	[221]	[120,92,NaN]	3	hSpCas9	negative selection	9860687
182582243	182582266	1	-	27869803	PATU8988S	viability after 31 days	TGTGCAGGACCTTGGACGGCTGG	RNASEL	ENSG00000135828	0.09730239101151478	[591]	[281,214,NaN]	1	hSpCas9	negative selection	9860688
182584143	182584166	1	-	27869803	PATU8988S	viability after 31 days	TTCTAAGAAAGCTGCTCACCTGG	RNASEL	ENSG00000135828	-0.03167545260676241	[294]	[89,146,NaN]	0	hSpCas9	negative selection	9860689
182585525	182585548	1	-	27869803	PATU8988S	viability after 31 days	CTATGGGAGTGAGAGCCACAGGG	RNASEL	ENSG00000135828	-0.2806876252166683	[864]	[341,209,NaN]	-3	hSpCas9	negative selection	9860690
182585526	182585549	1	-	27869803	PATU8988S	viability after 31 days	TCTATGGGAGTGAGAGCCACAGG	RNASEL	ENSG00000135828	-0.5906512968331425	[194]	[15,96,NaN]	-6	hSpCas9	negative selection	9860691
182575382	182575405	1	+	27869803	HPAFII	viability after 35 days	AATCAGTCCATCAGCACCCAGGG	RNASEL	ENSG00000135828	-0.5350835660538604	[255]	[24,161,NaN]	-3	hSpCas9	negative selection	9943135
182582222	182582245	1	-	27869803	HPAFII	viability after 35 days	GGTCCTCTATGTGGTAAAGAAGG	RNASEL	ENSG00000135828	0.1785751415887381	[115]	[49,84,NaN]	1	hSpCas9	negative selection	9943136
182582243	182582266	1	-	27869803	HPAFII	viability after 35 days	TGTGCAGGACCTTGGACGGCTGG	RNASEL	ENSG00000135828	1.5613225516549887	[256]	[446,312,NaN]	9	hSpCas9	negative selection	9943137
182584143	182584166	1	-	27869803	HPAFII	viability after 35 days	TTCTAAGAAAGCTGCTCACCTGG	RNASEL	ENSG00000135828	-1.0988314423868921	[164]	[38,38,NaN]	-6	hSpCas9	negative selection	9943138
182585525	182585548	1	-	27869803	HPAFII	viability after 35 days	CTATGGGAGTGAGAGCCACAGGG	RNASEL	ENSG00000135828	0.8017981647911996	[440]	[423,349,NaN]	5	hSpCas9	negative selection	9943139
182585526	182585549	1	-	27869803	HPAFII	viability after 35 days	TCTATGGGAGTGAGAGCCACAGG	RNASEL	ENSG00000135828	-1.4836899064747051	[103]	[23,12,NaN]	-7	hSpCas9	negative selection	9943140
182575382	182575405	1	+	27869803	HPAFII	viability after 31 days	AATCAGTCCATCAGCACCCAGGG	RNASEL	ENSG00000135828	-1.1867341139144338	[255]	[20,108,NaN]	-6	hSpCas9	negative selection	10025584
182582222	182582245	1	-	27869803	HPAFII	viability after 31 days	GGTCCTCTATGTGGTAAAGAAGG	RNASEL	ENSG00000135828	0.6989292636840029	[115]	[64,149,NaN]	5	hSpCas9	negative selection	10025585
182582243	182582266	1	-	27869803	HPAFII	viability after 31 days	TGTGCAGGACCTTGGACGGCTGG	RNASEL	ENSG00000135828	1.5458391285087176	[256]	[501,332,NaN]	9	hSpCas9	negative selection	10025586
182584143	182584166	1	-	27869803	HPAFII	viability after 31 days	TTCTAAGAAAGCTGCTCACCTGG	RNASEL	ENSG00000135828	-0.489806522870042	[164]	[86,42,NaN]	-3	hSpCas9	negative selection	10025587
182585525	182585548	1	-	27869803	HPAFII	viability after 31 days	CTATGGGAGTGAGAGCCACAGGG	RNASEL	ENSG00000135828	0.637263614540196	[440]	[394,373,NaN]	4	hSpCas9	negative selection	10025588
182585526	182585549	1	-	27869803	HPAFII	viability after 31 days	TCTATGGGAGTGAGAGCCACAGG	RNASEL	ENSG00000135828	-2.3798026916318116	[103]	[15,5,NaN]	-8	hSpCas9	negative selection	10025589
182586302	182586325	1	-	28162770	P31FUJ	viability	AGAGCGGCTGAGGAAAGGAGGGG	RNASEL	ENSG00000135828	-0.8268098447385417	[79]	[52]	-6	hSpCas9	negative selection	10225888
182585617	182585640	1	-	28162770	P31FUJ	viability	GCTGTGAAGACGTTCTGTGAGGG	RNASEL	ENSG00000135828	0.33614007571630533	[814]	[1208]	3	hSpCas9	negative selection	10225889
182585846	182585869	1	+	28162770	P31FUJ	viability	GAAGAACCTTCACAAGGGAATGG	RNASEL	ENSG00000135828	0.09734639727795213	[384]	[483]	1	hSpCas9	negative selection	10225890
182585723	182585746	1	+	28162770	P31FUJ	viability	TGAGTTTGCCAATCATAGGGCGG	RNASEL	ENSG00000135828	-0.07660609772664828	[480]	[535]	0	hSpCas9	negative selection	10225891
182585598	182585621	1	-	28162770	P31FUJ	viability	AGGGCAGCCCACGTGCACAGCGG	RNASEL	ENSG00000135828	0.5312686199144254	[115]	[196]	6	hSpCas9	negative selection	10225892
182586754	182586777	1	-	28162770	P31FUJ	viability	GAGGGACCCACGTCCTCCAGCGG	RNASEL	ENSG00000135828	0.24232574470079457	[240]	[334]	2	hSpCas9	negative selection	10225893
182586329	182586352	1	-	28162770	P31FUJ	viability	TTTGAGGCGAAAGACAAAGGAGG	RNASEL	ENSG00000135828	1.0947724536141257	[101]	[255]	9	hSpCas9	negative selection	10225894
182586233	182586256	1	-	28162770	P31FUJ	viability	GAAGATTCTCCTTGATGAGATGG	RNASEL	ENSG00000135828	0.3081356724147794	[243]	[354]	3	hSpCas9	negative selection	10225895
182585776	182585799	1	-	28162770	P31FUJ	viability	AAGCCTCAGAGCTCACACTGGGG	RNASEL	ENSG00000135828	0.15532742140094813	[229]	[300]	1	hSpCas9	negative selection	10225896
182585661	182585684	1	-	28162770	P31FUJ	viability	CAGAAGGAGGCATCTACCTGGGG	RNASEL	ENSG00000135828	-0.1638244624957952	[632]	[663]	-1	hSpCas9	negative selection	10225897
182586302	182586325	1	-	28162770	TF1	viability	AGAGCGGCTGAGGAAAGGAGGGG	RNASEL	ENSG00000135828	NaN	[NaN]	[67]	1	hSpCas9	negative selection	10395254
182585617	182585640	1	-	28162770	TF1	viability	GCTGTGAAGACGTTCTGTGAGGG	RNASEL	ENSG00000135828	NaN	[NaN]	[581]	1	hSpCas9	negative selection	10395255
182585846	182585869	1	+	28162770	TF1	viability	GAAGAACCTTCACAAGGGAATGG	RNASEL	ENSG00000135828	NaN	[NaN]	[374]	1	hSpCas9	negative selection	10395256
182585723	182585746	1	+	28162770	TF1	viability	TGAGTTTGCCAATCATAGGGCGG	RNASEL	ENSG00000135828	NaN	[NaN]	[333]	1	hSpCas9	negative selection	10395257
182585598	182585621	1	-	28162770	TF1	viability	AGGGCAGCCCACGTGCACAGCGG	RNASEL	ENSG00000135828	NaN	[NaN]	[133]	1	hSpCas9	negative selection	10395258
182586754	182586777	1	-	28162770	TF1	viability	GAGGGACCCACGTCCTCCAGCGG	RNASEL	ENSG00000135828	NaN	[NaN]	[204]	1	hSpCas9	negative selection	10395259
182586329	182586352	1	-	28162770	TF1	viability	TTTGAGGCGAAAGACAAAGGAGG	RNASEL	ENSG00000135828	NaN	[NaN]	[120]	1	hSpCas9	negative selection	10395260
182586233	182586256	1	-	28162770	TF1	viability	GAAGATTCTCCTTGATGAGATGG	RNASEL	ENSG00000135828	NaN	[NaN]	[201]	1	hSpCas9	negative selection	10395261
182585776	182585799	1	-	28162770	TF1	viability	AAGCCTCAGAGCTCACACTGGGG	RNASEL	ENSG00000135828	NaN	[NaN]	[283]	1	hSpCas9	negative selection	10395262
182585661	182585684	1	-	28162770	TF1	viability	CAGAAGGAGGCATCTACCTGGGG	RNASEL	ENSG00000135828	NaN	[NaN]	[419]	1	hSpCas9	negative selection	10395263
182586302	182586325	1	-	28162770	SKM1	viability	AGAGCGGCTGAGGAAAGGAGGGG	RNASEL	ENSG00000135828	0.1779983019779945	[21]	[43]	1	hSpCas9	negative selection	10564620
182585617	182585640	1	-	28162770	SKM1	viability	GCTGTGAAGACGTTCTGTGAGGG	RNASEL	ENSG00000135828	0.6758622323864585	[164]	[465]	6	hSpCas9	negative selection	10564621
182585846	182585869	1	+	28162770	SKM1	viability	GAAGAACCTTCACAAGGGAATGG	RNASEL	ENSG00000135828	-0.4395320611995924	[111]	[145]	-4	hSpCas9	negative selection	10564622
182585723	182585746	1	+	28162770	SKM1	viability	TGAGTTTGCCAATCATAGGGCGG	RNASEL	ENSG00000135828	-0.0747677684019723	[139]	[234]	0	hSpCas9	negative selection	10564623
182585598	182585621	1	-	28162770	SKM1	viability	AGGGCAGCCCACGTGCACAGCGG	RNASEL	ENSG00000135828	0.008073300535682226	[35]	[63]	0	hSpCas9	negative selection	10564624
182586754	182586777	1	-	28162770	SKM1	viability	GAGGGACCCACGTCCTCCAGCGG	RNASEL	ENSG00000135828	-0.7863777882912841	[79]	[81]	-5	hSpCas9	negative selection	10564625
182586329	182586352	1	-	28162770	SKM1	viability	TTTGAGGCGAAAGACAAAGGAGG	RNASEL	ENSG00000135828	-0.17563865263670597	[22]	[35]	-1	hSpCas9	negative selection	10564626
182586233	182586256	1	-	28162770	SKM1	viability	GAAGATTCTCCTTGATGAGATGG	RNASEL	ENSG00000135828	0.48056107199842585	[59]	[147]	4	hSpCas9	negative selection	10564627
182585776	182585799	1	-	28162770	SKM1	viability	AAGCCTCAGAGCTCACACTGGGG	RNASEL	ENSG00000135828	-0.7789329761301196	[65]	[67]	-5	hSpCas9	negative selection	10564628
182585661	182585684	1	-	28162770	SKM1	viability	CAGAAGGAGGCATCTACCTGGGG	RNASEL	ENSG00000135828	0.25756555929631264	[96]	[204]	2	hSpCas9	negative selection	10564629
182586302	182586325	1	-	28162770	SKM1	viability	AGAGCGGCTGAGGAAAGGAGGGG	RNASEL	ENSG00000135828	0.1779983019779945	[21]	[43]	1	hSpCas9	negative selection	10733986
182585617	182585640	1	-	28162770	SKM1	viability	GCTGTGAAGACGTTCTGTGAGGG	RNASEL	ENSG00000135828	0.6758622323864585	[164]	[465]	6	hSpCas9	negative selection	10733987
182585846	182585869	1	+	28162770	SKM1	viability	GAAGAACCTTCACAAGGGAATGG	RNASEL	ENSG00000135828	-0.4395320611995924	[111]	[145]	-4	hSpCas9	negative selection	10733988
182585723	182585746	1	+	28162770	SKM1	viability	TGAGTTTGCCAATCATAGGGCGG	RNASEL	ENSG00000135828	-0.0747677684019723	[139]	[234]	0	hSpCas9	negative selection	10733989
182585598	182585621	1	-	28162770	SKM1	viability	AGGGCAGCCCACGTGCACAGCGG	RNASEL	ENSG00000135828	0.008073300535682226	[35]	[63]	0	hSpCas9	negative selection	10733990
182586754	182586777	1	-	28162770	SKM1	viability	GAGGGACCCACGTCCTCCAGCGG	RNASEL	ENSG00000135828	-0.7863777882912841	[79]	[81]	-5	hSpCas9	negative selection	10733991
182586329	182586352	1	-	28162770	SKM1	viability	TTTGAGGCGAAAGACAAAGGAGG	RNASEL	ENSG00000135828	-0.17563865263670597	[22]	[35]	-1	hSpCas9	negative selection	10733992
182586233	182586256	1	-	28162770	SKM1	viability	GAAGATTCTCCTTGATGAGATGG	RNASEL	ENSG00000135828	0.48056107199842585	[59]	[147]	4	hSpCas9	negative selection	10733993
182585776	182585799	1	-	28162770	SKM1	viability	AAGCCTCAGAGCTCACACTGGGG	RNASEL	ENSG00000135828	-0.7789329761301196	[65]	[67]	-5	hSpCas9	negative selection	10733994
182585661	182585684	1	-	28162770	SKM1	viability	CAGAAGGAGGCATCTACCTGGGG	RNASEL	ENSG00000135828	0.25756555929631264	[96]	[204]	2	hSpCas9	negative selection	10733995
182586302	182586325	1	-	28162770	PL21	viability	AGAGCGGCTGAGGAAAGGAGGGG	RNASEL	ENSG00000135828	-0.9345099122054614	[100]	[22]	-6	hSpCas9	negative selection	10903352
182585617	182585640	1	-	28162770	PL21	viability	GCTGTGAAGACGTTCTGTGAGGG	RNASEL	ENSG00000135828	-0.40535981723453074	[565]	[185]	-3	hSpCas9	negative selection	10903353
182585846	182585869	1	+	28162770	PL21	viability	GAAGAACCTTCACAAGGGAATGG	RNASEL	ENSG00000135828	-0.2674097219506655	[400]	[144]	-2	hSpCas9	negative selection	10903354
182585723	182585746	1	+	28162770	PL21	viability	TGAGTTTGCCAATCATAGGGCGG	RNASEL	ENSG00000135828	0.12762711470495214	[407]	[193]	1	hSpCas9	negative selection	10903355
182585598	182585621	1	-	28162770	PL21	viability	AGGGCAGCCCACGTGCACAGCGG	RNASEL	ENSG00000135828	0.22438716073599757	[117]	[59]	2	hSpCas9	negative selection	10903356
182586754	182586777	1	-	28162770	PL21	viability	GAGGGACCCACGTCCTCCAGCGG	RNASEL	ENSG00000135828	-0.654767237048303	[292]	[80]	-4	hSpCas9	negative selection	10903357
182586329	182586352	1	-	28162770	PL21	viability	TTTGAGGCGAAAGACAAAGGAGG	RNASEL	ENSG00000135828	-2.865949575968453	[66]	[3]	-9	hSpCas9	negative selection	10903358
182586233	182586256	1	-	28162770	PL21	viability	GAAGATTCTCCTTGATGAGATGG	RNASEL	ENSG00000135828	-0.8689020299403313	[213]	[50]	-5	hSpCas9	negative selection	10903359
182585776	182585799	1	-	28162770	PL21	viability	AAGCCTCAGAGCTCACACTGGGG	RNASEL	ENSG00000135828	-0.71287708391604	[176]	[46]	-5	hSpCas9	negative selection	10903360
182585661	182585684	1	-	28162770	PL21	viability	CAGAAGGAGGCATCTACCTGGGG	RNASEL	ENSG00000135828	0.4175771538830034	[374]	[217]	3	hSpCas9	negative selection	10903361
182586302	182586325	1	-	28162770	P31FUJ	viability	AGAGCGGCTGAGGAAAGGAGGGG	RNASEL	ENSG00000135828	-0.8268098447385417	[79]	[52]	-6	hSpCas9	negative selection	11072718
182585617	182585640	1	-	28162770	P31FUJ	viability	GCTGTGAAGACGTTCTGTGAGGG	RNASEL	ENSG00000135828	0.33614007571630533	[814]	[1208]	3	hSpCas9	negative selection	11072719
182585846	182585869	1	+	28162770	P31FUJ	viability	GAAGAACCTTCACAAGGGAATGG	RNASEL	ENSG00000135828	0.09734639727795213	[384]	[483]	1	hSpCas9	negative selection	11072720
182585723	182585746	1	+	28162770	P31FUJ	viability	TGAGTTTGCCAATCATAGGGCGG	RNASEL	ENSG00000135828	-0.07660609772664828	[480]	[535]	0	hSpCas9	negative selection	11072721
182585598	182585621	1	-	28162770	P31FUJ	viability	AGGGCAGCCCACGTGCACAGCGG	RNASEL	ENSG00000135828	0.5312686199144254	[115]	[196]	6	hSpCas9	negative selection	11072722
182586754	182586777	1	-	28162770	P31FUJ	viability	GAGGGACCCACGTCCTCCAGCGG	RNASEL	ENSG00000135828	0.24232574470079457	[240]	[334]	2	hSpCas9	negative selection	11072723
182586329	182586352	1	-	28162770	P31FUJ	viability	TTTGAGGCGAAAGACAAAGGAGG	RNASEL	ENSG00000135828	1.0947724536141257	[101]	[255]	9	hSpCas9	negative selection	11072724
182586233	182586256	1	-	28162770	P31FUJ	viability	GAAGATTCTCCTTGATGAGATGG	RNASEL	ENSG00000135828	0.3081356724147794	[243]	[354]	3	hSpCas9	negative selection	11072725
182585776	182585799	1	-	28162770	P31FUJ	viability	AAGCCTCAGAGCTCACACTGGGG	RNASEL	ENSG00000135828	0.15532742140094813	[229]	[300]	1	hSpCas9	negative selection	11072726
182585661	182585684	1	-	28162770	P31FUJ	viability	CAGAAGGAGGCATCTACCTGGGG	RNASEL	ENSG00000135828	-0.1638244624957952	[632]	[663]	-1	hSpCas9	negative selection	11072727
182586302	182586325	1	-	28162770	OCIAML5	viability	AGAGCGGCTGAGGAAAGGAGGGG	RNASEL	ENSG00000135828	0.45171417731310615	[31]	[78]	4	hSpCas9	negative selection	11242084
182585617	182585640	1	-	28162770	OCIAML5	viability	GCTGTGAAGACGTTCTGTGAGGG	RNASEL	ENSG00000135828	-0.22351480159515802	[488]	[755]	-2	hSpCas9	negative selection	11242085
182585846	182585869	1	+	28162770	OCIAML5	viability	GAAGAACCTTCACAAGGGAATGG	RNASEL	ENSG00000135828	1.1010123817485105	[124]	[483]	8	hSpCas9	negative selection	11242086
182585723	182585746	1	+	28162770	OCIAML5	viability	TGAGTTTGCCAATCATAGGGCGG	RNASEL	ENSG00000135828	-0.049041902305126284	[285]	[498]	0	hSpCas9	negative selection	11242087
182585598	182585621	1	-	28162770	OCIAML5	viability	AGGGCAGCCCACGTGCACAGCGG	RNASEL	ENSG00000135828	0.46986152402336545	[47]	[119]	4	hSpCas9	negative selection	11242088
182586754	182586777	1	-	28162770	OCIAML5	viability	GAGGGACCCACGTCCTCCAGCGG	RNASEL	ENSG00000135828	-0.21374084454411568	[114]	[178]	-1	hSpCas9	negative selection	11242089
182586329	182586352	1	-	28162770	OCIAML5	viability	TTTGAGGCGAAAGACAAAGGAGG	RNASEL	ENSG00000135828	1.0460538151167897	[32]	[122]	8	hSpCas9	negative selection	11242090
182586233	182586256	1	-	28162770	OCIAML5	viability	GAAGATTCTCCTTGATGAGATGG	RNASEL	ENSG00000135828	1.0315047541593967	[157]	[582]	8	hSpCas9	negative selection	11242091
182585776	182585799	1	-	28162770	OCIAML5	viability	AAGCCTCAGAGCTCACACTGGGG	RNASEL	ENSG00000135828	-0.9600492517370087	[207]	[192]	-6	hSpCas9	negative selection	11242092
182585661	182585684	1	-	28162770	OCIAML5	viability	CAGAAGGAGGCATCTACCTGGGG	RNASEL	ENSG00000135828	0.24226081168415625	[258]	[552]	2	hSpCas9	negative selection	11242093
182586302	182586325	1	-	28162770	EOL1	viability	AGAGCGGCTGAGGAAAGGAGGGG	RNASEL	ENSG00000135828	-1.10144743696241	[223]	[54]	-6	hSpCas9	negative selection	11411450
182585617	182585640	1	-	28162770	EOL1	viability	GCTGTGAAGACGTTCTGTGAGGG	RNASEL	ENSG00000135828	0.11555806742198516	[882]	[503]	1	hSpCas9	negative selection	11411451
182585846	182585869	1	+	28162770	EOL1	viability	GAAGAACCTTCACAAGGGAATGG	RNASEL	ENSG00000135828	0.7529824117469666	[659]	[585]	6	hSpCas9	negative selection	11411452
182585723	182585746	1	+	28162770	EOL1	viability	TGAGTTTGCCAATCATAGGGCGG	RNASEL	ENSG00000135828	0.8895480621900747	[750]	[732]	7	hSpCas9	negative selection	11411453
182585598	182585621	1	-	28162770	EOL1	viability	AGGGCAGCCCACGTGCACAGCGG	RNASEL	ENSG00000135828	-0.17060946146980577	[234]	[109]	-1	hSpCas9	negative selection	11411454
182586754	182586777	1	-	28162770	EOL1	viability	GAGGGACCCACGTCCTCCAGCGG	RNASEL	ENSG00000135828	-0.1846156719171992	[493]	[228]	-1	hSpCas9	negative selection	11411455
182586329	182586352	1	-	28162770	EOL1	viability	TTTGAGGCGAAAGACAAAGGAGG	RNASEL	ENSG00000135828	-2.308112985219741	[93]	[9]	-8	hSpCas9	negative selection	11411456
182586233	182586256	1	-	28162770	EOL1	viability	GAAGATTCTCCTTGATGAGATGG	RNASEL	ENSG00000135828	0.11240778694755359	[301]	[171]	1	hSpCas9	negative selection	11411457
182585776	182585799	1	-	28162770	EOL1	viability	AAGCCTCAGAGCTCACACTGGGG	RNASEL	ENSG00000135828	-0.3264138019626842	[237]	[99]	-2	hSpCas9	negative selection	11411458
182585661	182585684	1	-	28162770	EOL1	viability	CAGAAGGAGGCATCTACCTGGGG	RNASEL	ENSG00000135828	-0.32685863201042004	[518]	[217]	-2	hSpCas9	negative selection	11411459
182586302	182586325	1	-	28162770	MOLM13	viability	AGAGCGGCTGAGGAAAGGAGGGG	RNASEL	ENSG00000135828	0.26065676737913657	[141]	[122]	1	hSpCas9	negative selection	11580816
182585617	182585640	1	-	28162770	MOLM13	viability	GCTGTGAAGACGTTCTGTGAGGG	RNASEL	ENSG00000135828	0.27691505658669646	[862]	[755]	2	hSpCas9	negative selection	11580817
182585846	182585869	1	+	28162770	MOLM13	viability	GAAGAACCTTCACAAGGGAATGG	RNASEL	ENSG00000135828	0.5446151721874073	[475]	[501]	4	hSpCas9	negative selection	11580818
182585723	182585746	1	+	28162770	MOLM13	viability	TGAGTTTGCCAATCATAGGGCGG	RNASEL	ENSG00000135828	0.6811707521812729	[589]	[683]	5	hSpCas9	negative selection	11580819
182585598	182585621	1	-	28162770	MOLM13	viability	AGGGCAGCCCACGTGCACAGCGG	RNASEL	ENSG00000135828	1.2199618681009934	[189]	[319]	8	hSpCas9	negative selection	11580820
182586754	182586777	1	-	28162770	MOLM13	viability	GAGGGACCCACGTCCTCCAGCGG	RNASEL	ENSG00000135828	-0.08258474279128658	[371]	[253]	0	hSpCas9	negative selection	11580821
182586329	182586352	1	-	28162770	MOLM13	viability	TTTGAGGCGAAAGACAAAGGAGG	RNASEL	ENSG00000135828	-1.1668261543736769	[117]	[37]	-6	hSpCas9	negative selection	11580822
182586233	182586256	1	-	28162770	MOLM13	viability	GAAGATTCTCCTTGATGAGATGG	RNASEL	ENSG00000135828	1.1572626043018421	[301]	[486]	8	hSpCas9	negative selection	11580823
182585776	182585799	1	-	28162770	MOLM13	viability	AAGCCTCAGAGCTCACACTGGGG	RNASEL	ENSG00000135828	-0.562916665236596	[283]	[138]	-3	hSpCas9	negative selection	11580824
182585661	182585684	1	-	28162770	MOLM13	viability	CAGAAGGAGGCATCTACCTGGGG	RNASEL	ENSG00000135828	1.3568580691558347	[458]	[849]	9	hSpCas9	negative selection	11580825
182586302	182586325	1	-	28162770	HEL	viability	AGAGCGGCTGAGGAAAGGAGGGG	RNASEL	ENSG00000135828	0.47648948870144303	[146]	[130]	4	hSpCas9	negative selection	11750182
182585617	182585640	1	-	28162770	HEL	viability	GCTGTGAAGACGTTCTGTGAGGG	RNASEL	ENSG00000135828	-0.3041273454695703	[772]	[400]	-2	hSpCas9	negative selection	11750183
182585846	182585869	1	+	28162770	HEL	viability	GAAGAACCTTCACAAGGGAATGG	RNASEL	ENSG00000135828	0.5574915453818459	[487]	[459]	5	hSpCas9	negative selection	11750184
182585723	182585746	1	+	28162770	HEL	viability	TGAGTTTGCCAATCATAGGGCGG	RNASEL	ENSG00000135828	0.30570384472278644	[527]	[417]	2	hSpCas9	negative selection	11750185
182585598	182585621	1	-	28162770	HEL	viability	AGGGCAGCCCACGTGCACAGCGG	RNASEL	ENSG00000135828	0.6502725046857645	[190]	[191]	5	hSpCas9	negative selection	11750186
182586754	182586777	1	-	28162770	HEL	viability	GAGGGACCCACGTCCTCCAGCGG	RNASEL	ENSG00000135828	-0.503809831352585	[351]	[158]	-3	hSpCas9	negative selection	11750187
182586329	182586352	1	-	28162770	HEL	viability	TTTGAGGCGAAAGACAAAGGAGG	RNASEL	ENSG00000135828	0.9771578710709161	[45]	[57]	8	hSpCas9	negative selection	11750188
182586233	182586256	1	-	28162770	HEL	viability	GAAGATTCTCCTTGATGAGATGG	RNASEL	ENSG00000135828	1.0091024845435113	[210]	[271]	8	hSpCas9	negative selection	11750189
182585776	182585799	1	-	28162770	HEL	viability	AAGCCTCAGAGCTCACACTGGGG	RNASEL	ENSG00000135828	-0.13570339814200832	[246]	[143]	-1	hSpCas9	negative selection	11750190
182585661	182585684	1	-	28162770	HEL	viability	CAGAAGGAGGCATCTACCTGGGG	RNASEL	ENSG00000135828	0.02747773074616211	[408]	[266]	0	hSpCas9	negative selection	11750191
182586302	182586325	1	-	28162770	MV411	viability	AGAGCGGCTGAGGAAAGGAGGGG	RNASEL	ENSG00000135828	-0.11784691329896901	[75]	[58]	-1	hSpCas9	negative selection	11919548
182585617	182585640	1	-	28162770	MV411	viability	GCTGTGAAGACGTTCTGTGAGGG	RNASEL	ENSG00000135828	0.7721649443705614	[537]	[773]	7	hSpCas9	negative selection	11919549
182585846	182585869	1	+	28162770	MV411	viability	GAAGAACCTTCACAAGGGAATGG	RNASEL	ENSG00000135828	-0.4152472453628986	[428]	[270]	-3	hSpCas9	negative selection	11919550
182585723	182585746	1	+	28162770	MV411	viability	TGAGTTTGCCAATCATAGGGCGG	RNASEL	ENSG00000135828	0.1095969093678204	[427]	[388]	0	hSpCas9	negative selection	11919551
182585598	182585621	1	-	28162770	MV411	viability	AGGGCAGCCCACGTGCACAGCGG	RNASEL	ENSG00000135828	0.9609147920266117	[160]	[263]	8	hSpCas9	negative selection	11919552
182586754	182586777	1	-	28162770	MV411	viability	GAGGGACCCACGTCCTCCAGCGG	RNASEL	ENSG00000135828	-0.3612410189121884	[275]	[180]	-3	hSpCas9	negative selection	11919553
182586329	182586352	1	-	28162770	MV411	viability	TTTGAGGCGAAAGACAAAGGAGG	RNASEL	ENSG00000135828	-0.9541963103868754	[68]	[29]	-6	hSpCas9	negative selection	11919554
182586233	182586256	1	-	28162770	MV411	viability	GAAGATTCTCCTTGATGAGATGG	RNASEL	ENSG00000135828	0.8324000515039315	[209]	[314]	7	hSpCas9	negative selection	11919555
182585776	182585799	1	-	28162770	MV411	viability	AAGCCTCAGAGCTCACACTGGGG	RNASEL	ENSG00000135828	-0.10899339150452633	[200]	[156]	-1	hSpCas9	negative selection	11919556
182585661	182585684	1	-	28162770	MV411	viability	CAGAAGGAGGCATCTACCTGGGG	RNASEL	ENSG00000135828	-0.1321511124917787	[401]	[308]	-1	hSpCas9	negative selection	11919557
182586302	182586325	1	-	28162770	MONOMAC1	viability	AGAGCGGCTGAGGAAAGGAGGGG	RNASEL	ENSG00000135828	-0.286304185156641	[49]	[46]	-3	hSpCas9	negative selection	12088914
182585617	182585640	1	-	28162770	MONOMAC1	viability	GCTGTGAAGACGTTCTGTGAGGG	RNASEL	ENSG00000135828	-0.042763579989676614	[380]	[423]	0	hSpCas9	negative selection	12088915
182585846	182585869	1	+	28162770	MONOMAC1	viability	GAAGAACCTTCACAAGGGAATGG	RNASEL	ENSG00000135828	0.6062712419353484	[254]	[444]	6	hSpCas9	negative selection	12088916
182585723	182585746	1	+	28162770	MONOMAC1	viability	TGAGTTTGCCAATCATAGGGCGG	RNASEL	ENSG00000135828	0.13028450659802715	[266]	[334]	1	hSpCas9	negative selection	12088917
182585598	182585621	1	-	28162770	MONOMAC1	viability	AGGGCAGCCCACGTGCACAGCGG	RNASEL	ENSG00000135828	0.3253841875928898	[109]	[157]	3	hSpCas9	negative selection	12088918
182586754	182586777	1	-	28162770	MONOMAC1	viability	GAGGGACCCACGTCCTCCAGCGG	RNASEL	ENSG00000135828	0.2160706251208906	[186]	[248]	2	hSpCas9	negative selection	12088919
182586329	182586352	1	-	28162770	MONOMAC1	viability	TTTGAGGCGAAAGACAAAGGAGG	RNASEL	ENSG00000135828	-0.2459464475405002	[59]	[57]	-2	hSpCas9	negative selection	12088920
182586233	182586256	1	-	28162770	MONOMAC1	viability	GAAGATTCTCCTTGATGAGATGG	RNASEL	ENSG00000135828	0.8160193057658929	[164]	[332]	7	hSpCas9	negative selection	12088921
182585776	182585799	1	-	28162770	MONOMAC1	viability	AAGCCTCAGAGCTCACACTGGGG	RNASEL	ENSG00000135828	-0.3992256976728204	[129]	[112]	-3	hSpCas9	negative selection	12088922
182585661	182585684	1	-	28162770	MONOMAC1	viability	CAGAAGGAGGCATCTACCTGGGG	RNASEL	ENSG00000135828	-0.5622431903863913	[312]	[242]	-5	hSpCas9	negative selection	12088923
182586302	182586325	1	-	28162770	OCIAML2	viability	AGAGCGGCTGAGGAAAGGAGGGG	RNASEL	ENSG00000135828	-0.8856673245210049	[21]	[65]	-6	hSpCas9	negative selection	12258280
182585617	182585640	1	-	28162770	OCIAML2	viability	GCTGTGAAGACGTTCTGTGAGGG	RNASEL	ENSG00000135828	0.5830081383599117	[98]	[821]	5	hSpCas9	negative selection	12258281
182585846	182585869	1	+	28162770	OCIAML2	viability	GAAGAACCTTCACAAGGGAATGG	RNASEL	ENSG00000135828	0.06897214207911939	[69]	[406]	0	hSpCas9	negative selection	12258282
182585723	182585746	1	+	28162770	OCIAML2	viability	TGAGTTTGCCAATCATAGGGCGG	RNASEL	ENSG00000135828	-0.3515771535983976	[92]	[403]	-3	hSpCas9	negative selection	12258283
182585598	182585621	1	-	28162770	OCIAML2	viability	AGGGCAGCCCACGTGCACAGCGG	RNASEL	ENSG00000135828	-0.281968261218263	[33]	[154]	-2	hSpCas9	negative selection	12258284
182586754	182586777	1	-	28162770	OCIAML2	viability	GAGGGACCCACGTCCTCCAGCGG	RNASEL	ENSG00000135828	-0.9188341884562043	[43]	[128]	-6	hSpCas9	negative selection	12258285
182586329	182586352	1	-	28162770	OCIAML2	viability	TTTGAGGCGAAAGACAAAGGAGG	RNASEL	ENSG00000135828	-0.6446592250172098	[10]	[38]	-5	hSpCas9	negative selection	12258286
182586233	182586256	1	-	28162770	OCIAML2	viability	GAAGATTCTCCTTGATGAGATGG	RNASEL	ENSG00000135828	1.1757332201431385	[22]	[287]	9	hSpCas9	negative selection	12258287
182585776	182585799	1	-	28162770	OCIAML2	viability	AAGCCTCAGAGCTCACACTGGGG	RNASEL	ENSG00000135828	-0.15747193998253095	[32]	[163]	-1	hSpCas9	negative selection	12258288
182585661	182585684	1	-	28162770	OCIAML2	viability	CAGAAGGAGGCATCTACCTGGGG	RNASEL	ENSG00000135828	0.2785620712573045	[46]	[315]	2	hSpCas9	negative selection	12258289
182586302	182586325	1	-	28162770	OCIAML3	viability	AGAGCGGCTGAGGAAAGGAGGGG	RNASEL	ENSG00000135828	-1.1414954356266562	[18]	[25]	-7	hSpCas9	negative selection	12427646
182585617	182585640	1	-	28162770	OCIAML3	viability	GCTGTGAAGACGTTCTGTGAGGG	RNASEL	ENSG00000135828	0.1792214978288147	[164]	[563]	1	hSpCas9	negative selection	12427647
182585846	182585869	1	+	28162770	OCIAML3	viability	GAAGAACCTTCACAAGGGAATGG	RNASEL	ENSG00000135828	0.20972696605474384	[113]	[397]	2	hSpCas9	negative selection	12427648
182585723	182585746	1	+	28162770	OCIAML3	viability	TGAGTTTGCCAATCATAGGGCGG	RNASEL	ENSG00000135828	0.405992359675837	[123]	[495]	4	hSpCas9	negative selection	12427649
182585598	182585621	1	-	28162770	OCIAML3	viability	AGGGCAGCCCACGTGCACAGCGG	RNASEL	ENSG00000135828	-0.16401979957934787	[35]	[96]	-1	hSpCas9	negative selection	12427650
182586754	182586777	1	-	28162770	OCIAML3	viability	GAGGGACCCACGTCCTCCAGCGG	RNASEL	ENSG00000135828	-0.447166251994892	[55]	[123]	-3	hSpCas9	negative selection	12427651
182586329	182586352	1	-	28162770	OCIAML3	viability	TTTGAGGCGAAAGACAAAGGAGG	RNASEL	ENSG00000135828	-1.1896173852448277	[33]	[44]	-7	hSpCas9	negative selection	12427652
182586233	182586256	1	-	28162770	OCIAML3	viability	GAAGATTCTCCTTGATGAGATGG	RNASEL	ENSG00000135828	-0.10302128781202069	[73]	[207]	-1	hSpCas9	negative selection	12427653
182585776	182585799	1	-	28162770	OCIAML3	viability	AAGCCTCAGAGCTCACACTGGGG	RNASEL	ENSG00000135828	0.5477663208040002	[45]	[202]	5	hSpCas9	negative selection	12427654
182585661	182585684	1	-	28162770	OCIAML3	viability	CAGAAGGAGGCATCTACCTGGGG	RNASEL	ENSG00000135828	-0.7548038522272192	[127]	[228]	-5	hSpCas9	negative selection	12427655