Crispr

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 168433
• Symbol: RNF133
• Description: ring finger protein 133

DataSource: http://genomecrispr.dkfz.de/#!/results/RNF133

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
122698680	122698703	7	-	26472758	Jiyoye	viability	GGAGTTATAGTGCCACCAGAGGG	RNF133	ENSG00000188050	0.7598469998243434	[194]	[248]	5	hSpCas9	negative selection	137930
122697777	122697800	7	+	26472758	Jiyoye	viability	AAGTCATGCCATCAAGGTGAAGG	RNF133	ENSG00000188050	-0.1233393351929063	[116]	[80]	-1	hSpCas9	negative selection	137931
122698542	122698565	7	-	26472758	Jiyoye	viability	GCAACTGAGAAGGGAGCCAGTGG	RNF133	ENSG00000188050	0.22469732972047632	[100]	[88]	1	hSpCas9	negative selection	137932
122698390	122698413	7	-	26472758	Jiyoye	viability	GGGAGTTCTCATTACAGCCGTGG	RNF133	ENSG00000188050	1.1048146554660105	[118]	[192]	7	hSpCas9	negative selection	137933
122698856	122698879	7	+	26472758	Jiyoye	viability	GAACTTCATAAGCCAGGAAGAGG	RNF133	ENSG00000188050	-0.27449876028695996	[400]	[249]	-2	hSpCas9	negative selection	137934
122698047	122698070	7	-	26472758	Jiyoye	viability	GACCCCTGGATTTTACCCCATGG	RNF133	ENSG00000188050	0.520557180923616	[158]	[171]	4	hSpCas9	negative selection	137935
122698903	122698926	7	-	26472758	Jiyoye	viability	GAGAGAGATGCATCTACTCAAGG	RNF133	ENSG00000188050	0.48766529936624126	[121]	[128]	3	hSpCas9	negative selection	137936
122698593	122698616	7	-	26472758	Jiyoye	viability	CTTGCACTTATTGAACGGGGAGG	RNF133	ENSG00000188050	0.78666876392705	[112]	[146]	5	hSpCas9	negative selection	137937
122698373	122698396	7	+	26472758	Jiyoye	viability	CTTTCTCCCCACCTCAACCACGG	RNF133	ENSG00000188050	0.083410628138894	[392]	[313]	0	hSpCas9	negative selection	137938
122698250	122698273	7	-	26472758	Jiyoye	viability	CAAGGATTCAGAACCGGAGATGG	RNF133	ENSG00000188050	-0.33906802624834365	[363]	[216]	-2	hSpCas9	negative selection	137939
122698680	122698703	7	-	26472758	KBM7	viability	GGAGTTATAGTGCCACCAGAGGG	RNF133	ENSG00000188050	0.6795429424944259	[949,674]	[759,464]	7	hSpCas9	negative selection	329048
122697777	122697800	7	+	26472758	KBM7	viability	AAGTCATGCCATCAAGGTGAAGG	RNF133	ENSG00000188050	0.4502505754944207	[450,620]	[415,293]	5	hSpCas9	negative selection	329049
122698542	122698565	7	-	26472758	KBM7	viability	GCAACTGAGAAGGGAGCCAGTGG	RNF133	ENSG00000188050	0.6437674464857236	[530,527]	[517,276]	7	hSpCas9	negative selection	329050
122698390	122698413	7	-	26472758	KBM7	viability	GGGAGTTCTCATTACAGCCGTGG	RNF133	ENSG00000188050	0.2482297358904944	[400,212]	[177,156]	2	hSpCas9	negative selection	329051
122698856	122698879	7	+	26472758	KBM7	viability	GAACTTCATAAGCCAGGAAGAGG	RNF133	ENSG00000188050	0.4816503796761462	[919,774]	[775,355]	5	hSpCas9	negative selection	329052
122698047	122698070	7	-	26472758	KBM7	viability	GACCCCTGGATTTTACCCCATGG	RNF133	ENSG00000188050	0.9870595003357664	[424,248]	[406,217]	9	hSpCas9	negative selection	329053
122698903	122698926	7	-	26472758	KBM7	viability	GAGAGAGATGCATCTACTCAAGG	RNF133	ENSG00000188050	0.9030353534540765	[854,681]	[789,564]	8	hSpCas9	negative selection	329054
122698593	122698616	7	-	26472758	KBM7	viability	CTTGCACTTATTGAACGGGGAGG	RNF133	ENSG00000188050	0.2567829261925074	[605,412]	[223,333]	2	hSpCas9	negative selection	329055
122698373	122698396	7	+	26472758	KBM7	viability	CTTTCTCCCCACCTCAACCACGG	RNF133	ENSG00000188050	0.11793653124095949	[1295,1513]	[875,591]	1	hSpCas9	negative selection	329056
122698250	122698273	7	-	26472758	KBM7	viability	CAAGGATTCAGAACCGGAGATGG	RNF133	ENSG00000188050	0.1272504900763285	[1156,983]	[502,587]	1	hSpCas9	negative selection	329057
122698680	122698703	7	-	26472758	Raji	viability	GGAGTTATAGTGCCACCAGAGGG	RNF133	ENSG00000188050	0.4742263221828842	[486]	[156]	4	hSpCas9	negative selection	520166
122697777	122697800	7	+	26472758	Raji	viability	AAGTCATGCCATCAAGGTGAAGG	RNF133	ENSG00000188050	-1.0863882080230804	[365]	[39]	-7	hSpCas9	negative selection	520167
122698542	122698565	7	-	26472758	Raji	viability	GCAACTGAGAAGGGAGCCAGTGG	RNF133	ENSG00000188050	0.8231751064353957	[150]	[61]	7	hSpCas9	negative selection	520168
122698390	122698413	7	-	26472758	Raji	viability	GGGAGTTCTCATTACAGCCGTGG	RNF133	ENSG00000188050	1.5269224268873842	[159]	[106]	9	hSpCas9	negative selection	520169
122698856	122698879	7	+	26472758	Raji	viability	GAACTTCATAAGCCAGGAAGAGG	RNF133	ENSG00000188050	0.08691943281388392	[425]	[104]	0	hSpCas9	negative selection	520170
122698047	122698070	7	-	26472758	Raji	viability	GACCCCTGGATTTTACCCCATGG	RNF133	ENSG00000188050	0.7544285448656126	[234]	[91]	7	hSpCas9	negative selection	520171
122698903	122698926	7	-	26472758	Raji	viability	GAGAGAGATGCATCTACTCAAGG	RNF133	ENSG00000188050	0.9708104824981555	[309]	[140]	8	hSpCas9	negative selection	520172
122698593	122698616	7	-	26472758	Raji	viability	CTTGCACTTATTGAACGGGGAGG	RNF133	ENSG00000188050	-0.024322143838222676	[297]	[67]	0	hSpCas9	negative selection	520173
122698373	122698396	7	+	26472758	Raji	viability	CTTTCTCCCCACCTCAACCACGG	RNF133	ENSG00000188050	-0.07394622934096207	[761]	[167]	0	hSpCas9	negative selection	520174
122698250	122698273	7	-	26472758	Raji	viability	CAAGGATTCAGAACCGGAGATGG	RNF133	ENSG00000188050	0.5828948936787584	[583]	[202]	5	hSpCas9	negative selection	520175
122698680	122698703	7	-	26472758	K562	viability	GGAGTTATAGTGCCACCAGAGGG	RNF133	ENSG00000188050	0.6963476043972356	[665]	[910]	6	hSpCas9	negative selection	711284
122697777	122697800	7	+	26472758	K562	viability	AAGTCATGCCATCAAGGTGAAGG	RNF133	ENSG00000188050	0.8877816040354797	[467]	[730]	7	hSpCas9	negative selection	711285
122698542	122698565	7	-	26472758	K562	viability	GCAACTGAGAAGGGAGCCAGTGG	RNF133	ENSG00000188050	0.1585993592054431	[328]	[309]	1	hSpCas9	negative selection	711286
122698390	122698413	7	-	26472758	K562	viability	GGGAGTTCTCATTACAGCCGTGG	RNF133	ENSG00000188050	0.20062360978676191	[300]	[291]	1	hSpCas9	negative selection	711287
122698856	122698879	7	+	26472758	K562	viability	GAACTTCATAAGCCAGGAAGAGG	RNF133	ENSG00000188050	0.6895582587347099	[663]	[903]	5	hSpCas9	negative selection	711288
122698047	122698070	7	-	26472758	K562	viability	GACCCCTGGATTTTACCCCATGG	RNF133	ENSG00000188050	0.11354650278790916	[368]	[336]	0	hSpCas9	negative selection	711289
122698903	122698926	7	-	26472758	K562	viability	GAGAGAGATGCATCTACTCAAGG	RNF133	ENSG00000188050	0.5363198600018146	[601]	[736]	4	hSpCas9	negative selection	711290
122698593	122698616	7	-	26472758	K562	viability	CTTGCACTTATTGAACGGGGAGG	RNF133	ENSG00000188050	-1.3151584546347956	[506]	[171]	-6	hSpCas9	negative selection	711291
122698373	122698396	7	+	26472758	K562	viability	CTTTCTCCCCACCTCAACCACGG	RNF133	ENSG00000188050	0.21291503664438416	[1249]	[1222]	1	hSpCas9	negative selection	711292
122698250	122698273	7	-	26472758	K562	viability	CAAGGATTCAGAACCGGAGATGG	RNF133	ENSG00000188050	-0.027559879418396216	[808]	[669]	0	hSpCas9	negative selection	711293
122697847	122697870	7	+	26627737	DLD1	viability	AAGTAGGGTTCTCCTCCACATGG	RNF133	ENSG00000188050	-0.4439573683627882	[229]	[70,52,36]	-4	hSpCas9	negative selection	834681
122698381	122698404	7	-	26627737	DLD1	viability	CATTACAGCCGTGGTTGAGGTGG	RNF133	ENSG00000188050	0.7524487378373094	[384]	[203,182,217]	7	hSpCas9	negative selection	834682
122698390	122698413	7	-	26627737	DLD1	viability	GGGAGTTCTCATTACAGCCGTGG	RNF133	ENSG00000188050	-0.29635140481197164	[261]	[83,110,14]	-3	hSpCas9	negative selection	834683
122698596	122698619	7	-	26627737	DLD1	viability	TGGCTTGCACTTATTGAACGGGG	RNF133	ENSG00000188050	-0.08433477009038759	[1173]	[426,373,252]	-1	hSpCas9	negative selection	834684
122698597	122698620	7	-	26627737	DLD1	viability	CTGGCTTGCACTTATTGAACGGG	RNF133	ENSG00000188050	0.32687318398458864	[1332]	[717,516,357]	3	hSpCas9	negative selection	834685
122698616	122698639	7	-	26627737	DLD1	viability	GATCAAAGTACTCAGAGACCTGG	RNF133	ENSG00000188050	0.7430601809615892	[144]	[86,57,80]	7	hSpCas9	negative selection	834686
122697847	122697870	7	+	26627737	GBM cells	viability after 5 days	AAGTAGGGTTCTCCTCCACATGG	RNF133	ENSG00000188050	-0.14415484700620046	[203]	[92,104]	-2	hSpCas9	negative selection	916996
122698381	122698404	7	-	26627737	GBM cells	viability after 5 days	CATTACAGCCGTGGTTGAGGTGG	RNF133	ENSG00000188050	-0.06015586105943241	[277]	[175,109]	-1	hSpCas9	negative selection	916997
122698390	122698413	7	-	26627737	GBM cells	viability after 5 days	GGGAGTTCTCATTACAGCCGTGG	RNF133	ENSG00000188050	0.4792891061111899	[104]	[74,81]	7	hSpCas9	negative selection	916998
122698596	122698619	7	-	26627737	GBM cells	viability after 5 days	TGGCTTGCACTTATTGAACGGGG	RNF133	ENSG00000188050	0.06310250677885354	[671]	[377,374]	1	hSpCas9	negative selection	916999
122698597	122698620	7	-	26627737	GBM cells	viability after 5 days	CTGGCTTGCACTTATTGAACGGG	RNF133	ENSG00000188050	0.05345214289705513	[795]	[418,466]	0	hSpCas9	negative selection	917000
122698616	122698639	7	-	26627737	GBM cells	viability after 5 days	GATCAAAGTACTCAGAGACCTGG	RNF133	ENSG00000188050	0.06581118363042959	[105]	[53,64]	1	hSpCas9	negative selection	917001
122697847	122697870	7	+	26627737	GBM cells	viability after 13 days	AAGTAGGGTTCTCCTCCACATGG	RNF133	ENSG00000188050	0.07795564909601091	[203]	[123,110]	1	hSpCas9	negative selection	999311
122698381	122698404	7	-	26627737	GBM cells	viability after 13 days	CATTACAGCCGTGGTTGAGGTGG	RNF133	ENSG00000188050	-0.23443656209695862	[277]	[141,116]	-3	hSpCas9	negative selection	999312
122698390	122698413	7	-	26627737	GBM cells	viability after 13 days	GGGAGTTCTCATTACAGCCGTGG	RNF133	ENSG00000188050	-0.052712707661415115	[104]	[44,62]	0	hSpCas9	negative selection	999313
122698596	122698619	7	-	26627737	GBM cells	viability after 13 days	TGGCTTGCACTTATTGAACGGGG	RNF133	ENSG00000188050	0.4355737736480674	[671]	[598,406]	5	hSpCas9	negative selection	999314
122698597	122698620	7	-	26627737	GBM cells	viability after 13 days	CTGGCTTGCACTTATTGAACGGG	RNF133	ENSG00000188050	0.2344763856836618	[795]	[597,434]	3	hSpCas9	negative selection	999315
122698616	122698639	7	-	26627737	GBM cells	viability after 13 days	GATCAAAGTACTCAGAGACCTGG	RNF133	ENSG00000188050	-0.8567985710280694	[105]	[28,33]	-7	hSpCas9	negative selection	999316
122697847	122697870	7	+	26627737	GBM cells	viability after 21 days	AAGTAGGGTTCTCCTCCACATGG	RNF133	ENSG00000188050	0.621529900877152	[203]	[181,159]	6	hSpCas9	negative selection	1081626
122698381	122698404	7	-	26627737	GBM cells	viability after 21 days	CATTACAGCCGTGGTTGAGGTGG	RNF133	ENSG00000188050	-0.7863978835827354	[277]	[85,88]	-6	hSpCas9	negative selection	1081627
122698390	122698413	7	-	26627737	GBM cells	viability after 21 days	GGGAGTTCTCATTACAGCCGTGG	RNF133	ENSG00000188050	0.7645779607014669	[104]	[98,94]	7	hSpCas9	negative selection	1081628
122698596	122698619	7	-	26627737	GBM cells	viability after 21 days	TGGCTTGCACTTATTGAACGGGG	RNF133	ENSG00000188050	0.26295910002863954	[671]	[447,428]	2	hSpCas9	negative selection	1081629
122698597	122698620	7	-	26627737	GBM cells	viability after 21 days	CTGGCTTGCACTTATTGAACGGG	RNF133	ENSG00000188050	0.8446365760931245	[795]	[785,767]	8	hSpCas9	negative selection	1081630
122698616	122698639	7	-	26627737	GBM cells	viability after 21 days	GATCAAAGTACTCAGAGACCTGG	RNF133	ENSG00000188050	-0.2316693369976015	[105]	[47,49]	-2	hSpCas9	negative selection	1081631
122697847	122697870	7	+	26627737	RPE1	viability after 9 days	AAGTAGGGTTCTCCTCCACATGG	RNF133	ENSG00000188050	0.8662801356237966	[462]	[258,270]	5	hSpCas9	negative selection	1163941
122698381	122698404	7	-	26627737	RPE1	viability after 9 days	CATTACAGCCGTGGTTGAGGTGG	RNF133	ENSG00000188050	-0.01729979680732721	[701]	[324,77]	0	hSpCas9	negative selection	1163942
122698390	122698413	7	-	26627737	RPE1	viability after 9 days	GGGAGTTCTCATTACAGCCGTGG	RNF133	ENSG00000188050	-0.21987931366077662	[139]	[41,31]	-1	hSpCas9	negative selection	1163943
122698596	122698619	7	-	26627737	RPE1	viability after 9 days	TGGCTTGCACTTATTGAACGGGG	RNF133	ENSG00000188050	-0.43140187814450526	[3275]	[839,657]	-3	hSpCas9	negative selection	1163944
122698597	122698620	7	-	26627737	RPE1	viability after 9 days	CTGGCTTGCACTTATTGAACGGG	RNF133	ENSG00000188050	0.7735938671410245	[2296]	[1310,1123]	5	hSpCas9	negative selection	1163945
122698616	122698639	7	-	26627737	RPE1	viability after 9 days	GATCAAAGTACTCAGAGACCTGG	RNF133	ENSG00000188050	4.2220874250700176	[5]	[31,38]	9	hSpCas9	negative selection	1163946
122697847	122697870	7	+	26627737	RPE1	viability after 12 days	AAGTAGGGTTCTCCTCCACATGG	RNF133	ENSG00000188050	1.0465467648323	[462]	[271,240]	6	hSpCas9	negative selection	1246256
122698381	122698404	7	-	26627737	RPE1	viability after 12 days	CATTACAGCCGTGGTTGAGGTGG	RNF133	ENSG00000188050	0.1290844631012266	[701]	[299,106]	0	hSpCas9	negative selection	1246257
122698390	122698413	7	-	26627737	RPE1	viability after 12 days	GGGAGTTCTCATTACAGCCGTGG	RNF133	ENSG00000188050	-0.4155483477603976	[139]	[51,2]	-3	hSpCas9	negative selection	1246258
122698596	122698619	7	-	26627737	RPE1	viability after 12 days	TGGCTTGCACTTATTGAACGGGG	RNF133	ENSG00000188050	-0.5107456161836512	[3275]	[744,482]	-4	hSpCas9	negative selection	1246259
122698597	122698620	7	-	26627737	RPE1	viability after 12 days	CTGGCTTGCACTTATTGAACGGG	RNF133	ENSG00000188050	0.5026315765297842	[2296]	[902,843]	3	hSpCas9	negative selection	1246260
122698616	122698639	7	-	26627737	RPE1	viability after 12 days	GATCAAAGTACTCAGAGACCTGG	RNF133	ENSG00000188050	4.433348304627227	[5]	[28,40]	9	hSpCas9	negative selection	1246261
122697847	122697870	7	+	26627737	RPE1	viability after 15 days	AAGTAGGGTTCTCCTCCACATGG	RNF133	ENSG00000188050	1.2822862323139899	[462]	[455,185]	7	hSpCas9	negative selection	1328571
122698381	122698404	7	-	26627737	RPE1	viability after 15 days	CATTACAGCCGTGGTTGAGGTGG	RNF133	ENSG00000188050	0.9645752293911366	[701]	[610,171]	6	hSpCas9	negative selection	1328572
122698390	122698413	7	-	26627737	RPE1	viability after 15 days	GGGAGTTCTCATTACAGCCGTGG	RNF133	ENSG00000188050	0.11880651697936484	[139]	[70,15]	0	hSpCas9	negative selection	1328573
122698596	122698619	7	-	26627737	RPE1	viability after 15 days	TGGCTTGCACTTATTGAACGGGG	RNF133	ENSG00000188050	-0.5981616511998398	[3275]	[798,431]	-4	hSpCas9	negative selection	1328574
122698597	122698620	7	-	26627737	RPE1	viability after 15 days	CTGGCTTGCACTTATTGAACGGG	RNF133	ENSG00000188050	0.5429724174877621	[2296]	[1244,658]	3	hSpCas9	negative selection	1328575
122698616	122698639	7	-	26627737	RPE1	viability after 15 days	GATCAAAGTACTCAGAGACCTGG	RNF133	ENSG00000188050	4.7092888473130206	[5]	[49,38]	9	hSpCas9	negative selection	1328576
122697847	122697870	7	+	26627737	RPE1	viability after 18 days	AAGTAGGGTTCTCCTCCACATGG	RNF133	ENSG00000188050	1.1157373541509095	[462]	[336,199]	6	hSpCas9	negative selection	1410886
122698381	122698404	7	-	26627737	RPE1	viability after 18 days	CATTACAGCCGTGGTTGAGGTGG	RNF133	ENSG00000188050	0.8762428288611359	[701]	[558,121]	5	hSpCas9	negative selection	1410887
122698390	122698413	7	-	26627737	RPE1	viability after 18 days	GGGAGTTCTCATTACAGCCGTGG	RNF133	ENSG00000188050	-1.626999519457439	[139]	[18,4]	-7	hSpCas9	negative selection	1410888
122698596	122698619	7	-	26627737	RPE1	viability after 18 days	TGGCTTGCACTTATTGAACGGGG	RNF133	ENSG00000188050	-0.43781391266535286	[3275]	[657,646]	-3	hSpCas9	negative selection	1410889
122698597	122698620	7	-	26627737	RPE1	viability after 18 days	CTGGCTTGCACTTATTGAACGGG	RNF133	ENSG00000188050	0.438834392210419	[2296]	[949,722]	2	hSpCas9	negative selection	1410890
122698616	122698639	7	-	26627737	RPE1	viability after 18 days	GATCAAAGTACTCAGAGACCTGG	RNF133	ENSG00000188050	5.288806948735517	[5]	[71,53]	9	hSpCas9	negative selection	1410891
122697847	122697870	7	+	26627737	HeLa	viability after 8 days	AAGTAGGGTTCTCCTCCACATGG	RNF133	ENSG00000188050	1.0907115025780454	[166]	[164,108,189]	8	hSpCas9	negative selection	1493201
122698381	122698404	7	-	26627737	HeLa	viability after 8 days	CATTACAGCCGTGGTTGAGGTGG	RNF133	ENSG00000188050	1.7387206872873524	[141]	[393,74,191]	9	hSpCas9	negative selection	1493202
122698390	122698413	7	-	26627737	HeLa	viability after 8 days	GGGAGTTCTCATTACAGCCGTGG	RNF133	ENSG00000188050	-0.9398732357555464	[199]	[50,35,49]	-7	hSpCas9	negative selection	1493203
122698596	122698619	7	-	26627737	HeLa	viability after 8 days	TGGCTTGCACTTATTGAACGGGG	RNF133	ENSG00000188050	0.07150626766946777	[1220]	[785,602,350]	0	hSpCas9	negative selection	1493204
122698597	122698620	7	-	26627737	HeLa	viability after 8 days	CTGGCTTGCACTTATTGAACGGG	RNF133	ENSG00000188050	0.19778779355817777	[1351]	[972,606,520]	2	hSpCas9	negative selection	1493205
122698616	122698639	7	-	26627737	HeLa	viability after 8 days	GATCAAAGTACTCAGAGACCTGG	RNF133	ENSG00000188050	0.531934607477085	[87]	[45,76,41]	5	hSpCas9	negative selection	1493206
122697847	122697870	7	+	26627737	HeLa	viability after 12 days	AAGTAGGGTTCTCCTCCACATGG	RNF133	ENSG00000188050	0.8808174753353011	[166]	[131,111,138]	6	hSpCas9	negative selection	1575516
122698381	122698404	7	-	26627737	HeLa	viability after 12 days	CATTACAGCCGTGGTTGAGGTGG	RNF133	ENSG00000188050	1.8870319946519318	[141]	[201,138,317]	9	hSpCas9	negative selection	1575517
122698390	122698413	7	-	26627737	HeLa	viability after 12 days	GGGAGTTCTCATTACAGCCGTGG	RNF133	ENSG00000188050	0.6320007300935194	[199]	[183,60,147]	5	hSpCas9	negative selection	1575518
122698596	122698619	7	-	26627737	HeLa	viability after 12 days	TGGCTTGCACTTATTGAACGGGG	RNF133	ENSG00000188050	0.2814342349221921	[1220]	[606,581,653]	2	hSpCas9	negative selection	1575519
122698597	122698620	7	-	26627737	HeLa	viability after 12 days	CTGGCTTGCACTTATTGAACGGG	RNF133	ENSG00000188050	0.6160250809971142	[1351]	[1061,846,666]	5	hSpCas9	negative selection	1575520
122698616	122698639	7	-	26627737	HeLa	viability after 12 days	GATCAAAGTACTCAGAGACCTGG	RNF133	ENSG00000188050	0.36152534101896205	[87]	[72,64,0]	3	hSpCas9	negative selection	1575521
122697847	122697870	7	+	26627737	HeLa	viability after 15 days	AAGTAGGGTTCTCCTCCACATGG	RNF133	ENSG00000188050	0.6784329710051124	[166]	[81,120,124]	5	hSpCas9	negative selection	1657831
122698381	122698404	7	-	26627737	HeLa	viability after 15 days	CATTACAGCCGTGGTTGAGGTGG	RNF133	ENSG00000188050	1.6902274058942894	[141]	[273,43,244]	9	hSpCas9	negative selection	1657832
122698390	122698413	7	-	26627737	HeLa	viability after 15 days	GGGAGTTCTCATTACAGCCGTGG	RNF133	ENSG00000188050	-0.22311522373944737	[199]	[55,88,63]	-2	hSpCas9	negative selection	1657833
122698596	122698619	7	-	26627737	HeLa	viability after 15 days	TGGCTTGCACTTATTGAACGGGG	RNF133	ENSG00000188050	0.07937021346652773	[1220]	[394,514,678]	0	hSpCas9	negative selection	1657834
122698597	122698620	7	-	26627737	HeLa	viability after 15 days	CTGGCTTGCACTTATTGAACGGG	RNF133	ENSG00000188050	0.5647816726047019	[1351]	[743,731,979]	4	hSpCas9	negative selection	1657835
122698616	122698639	7	-	26627737	HeLa	viability after 15 days	GATCAAAGTACTCAGAGACCTGG	RNF133	ENSG00000188050	-0.011821866901053912	[87]	[13,79,10]	0	hSpCas9	negative selection	1657836
122697847	122697870	7	+	26627737	HeLa	viability after 18 days	AAGTAGGGTTCTCCTCCACATGG	RNF133	ENSG00000188050	0.7255606850820033	[166]	[58,103,124]	5	hSpCas9	negative selection	1740146
122698381	122698404	7	-	26627737	HeLa	viability after 18 days	CATTACAGCCGTGGTTGAGGTGG	RNF133	ENSG00000188050	1.6726607717972486	[141]	[178,36,244]	9	hSpCas9	negative selection	1740147
122698390	122698413	7	-	26627737	HeLa	viability after 18 days	GGGAGTTCTCATTACAGCCGTGG	RNF133	ENSG00000188050	-0.23517647238642603	[199]	[32,77,63]	-2	hSpCas9	negative selection	1740148
122698596	122698619	7	-	26627737	HeLa	viability after 18 days	TGGCTTGCACTTATTGAACGGGG	RNF133	ENSG00000188050	0.06748863057499954	[1220]	[252,430,678]	0	hSpCas9	negative selection	1740149
122698597	122698620	7	-	26627737	HeLa	viability after 18 days	CTGGCTTGCACTTATTGAACGGG	RNF133	ENSG00000188050	0.5544579508791292	[1351]	[487,605,979]	4	hSpCas9	negative selection	1740150
122698616	122698639	7	-	26627737	HeLa	viability after 18 days	GATCAAAGTACTCAGAGACCTGG	RNF133	ENSG00000188050	0.04973373512789658	[87]	[10,67,10]	0	hSpCas9	negative selection	1740151
122697847	122697870	7	+	26627737	HCT116	viability after 6 days	AAGTAGGGTTCTCCTCCACATGG	RNF133	ENSG00000188050	-1.0923638188990157	[175]	[21,7]	-6	hSpCas9	negative selection	1822461
122698381	122698404	7	-	26627737	HCT116	viability after 6 days	CATTACAGCCGTGGTTGAGGTGG	RNF133	ENSG00000188050	-0.2988637530645938	[698]	[127,67]	-2	hSpCas9	negative selection	1822462
122698390	122698413	7	-	26627737	HCT116	viability after 6 days	GGGAGTTCTCATTACAGCCGTGG	RNF133	ENSG00000188050	3.4412091803412004	[237]	[116,565]	9	hSpCas9	negative selection	1822463
122698596	122698619	7	-	26627737	HCT116	viability after 6 days	TGGCTTGCACTTATTGAACGGGG	RNF133	ENSG00000188050	0.8258019738488667	[1566]	[406,452]	4	hSpCas9	negative selection	1822464
122698597	122698620	7	-	26627737	HCT116	viability after 6 days	CTGGCTTGCACTTATTGAACGGG	RNF133	ENSG00000188050	0.7545443114717174	[2386]	[1169,336]	4	hSpCas9	negative selection	1822465
122698616	122698639	7	-	26627737	HCT116	viability after 6 days	GATCAAAGTACTCAGAGACCTGG	RNF133	ENSG00000188050	-2.409697853943193	[201]	[14,0]	-8	hSpCas9	negative selection	1822466
122697847	122697870	7	+	26627737	HCT116	viability after 8 days	AAGTAGGGTTCTCCTCCACATGG	RNF133	ENSG00000188050	-0.47852139679521055	[231]	[130,56,87]	-5	hSpCas9	negative selection	1904776
122698381	122698404	7	-	26627737	HCT116	viability after 8 days	CATTACAGCCGTGGTTGAGGTGG	RNF133	ENSG00000188050	0.754111080521731	[178]	[167,156,173]	7	hSpCas9	negative selection	1904777
122698390	122698413	7	-	26627737	HCT116	viability after 8 days	GGGAGTTCTCATTACAGCCGTGG	RNF133	ENSG00000188050	-0.21794201490613896	[230]	[118,141,67]	-2	hSpCas9	negative selection	1904778
122698596	122698619	7	-	26627737	HCT116	viability after 8 days	TGGCTTGCACTTATTGAACGGGG	RNF133	ENSG00000188050	-0.2636771194308394	[1036]	[437,494,493]	-3	hSpCas9	negative selection	1904779
122698597	122698620	7	-	26627737	HCT116	viability after 8 days	CTGGCTTGCACTTATTGAACGGG	RNF133	ENSG00000188050	1.2306853606216044	[442]	[663,465,589]	8	hSpCas9	negative selection	1904780
122698616	122698639	7	-	26627737	HCT116	viability after 8 days	GATCAAAGTACTCAGAGACCTGG	RNF133	ENSG00000188050	-0.4169576051597961	[112]	[46,52,39]	-5	hSpCas9	negative selection	1904781
122697847	122697870	7	+	26627737	HCT116	viability after 9 days	AAGTAGGGTTCTCCTCCACATGG	RNF133	ENSG00000188050	2.4352659223910065	[175]	[261,247]	9	hSpCas9	negative selection	1987091
122698381	122698404	7	-	26627737	HCT116	viability after 9 days	CATTACAGCCGTGGTTGAGGTGG	RNF133	ENSG00000188050	1.5411281945448385	[698]	[240,781]	8	hSpCas9	negative selection	1987092
122698390	122698413	7	-	26627737	HCT116	viability after 9 days	GGGAGTTCTCATTACAGCCGTGG	RNF133	ENSG00000188050	0.8354030316836822	[237]	[142,89]	6	hSpCas9	negative selection	1987093
122698596	122698619	7	-	26627737	HCT116	viability after 9 days	TGGCTTGCACTTATTGAACGGGG	RNF133	ENSG00000188050	-0.22411281467163047	[1566]	[441,291]	-1	hSpCas9	negative selection	1987094
122698597	122698620	7	-	26627737	HCT116	viability after 9 days	CTGGCTTGCACTTATTGAACGGG	RNF133	ENSG00000188050	-0.43925488029196	[2386]	[745,251]	-3	hSpCas9	negative selection	1987095
122698616	122698639	7	-	26627737	HCT116	viability after 9 days	GATCAAAGTACTCAGAGACCTGG	RNF133	ENSG00000188050	0.8523078993995147	[201]	[26,152]	6	hSpCas9	negative selection	1987096
122697847	122697870	7	+	26627737	HCT116	viability after 12 days	AAGTAGGGTTCTCCTCCACATGG	RNF133	ENSG00000188050	0.10095864046179176	[231]	[123,135,132]	1	hSpCas9	negative selection	2069406
122698381	122698404	7	-	26627737	HCT116	viability after 12 days	CATTACAGCCGTGGTTGAGGTGG	RNF133	ENSG00000188050	1.1250750034793788	[178]	[203,178,231]	8	hSpCas9	negative selection	2069407
122698390	122698413	7	-	26627737	HCT116	viability after 12 days	GGGAGTTCTCATTACAGCCGTGG	RNF133	ENSG00000188050	-0.17550545962418596	[230]	[115,159,46]	-2	hSpCas9	negative selection	2069408
122698596	122698619	7	-	26627737	HCT116	viability after 12 days	TGGCTTGCACTTATTGAACGGGG	RNF133	ENSG00000188050	-0.2623936829497424	[1036]	[465,453,441]	-3	hSpCas9	negative selection	2069409
122698597	122698620	7	-	26627737	HCT116	viability after 12 days	CTGGCTTGCACTTATTGAACGGG	RNF133	ENSG00000188050	1.1588928099464901	[442]	[509,587,463]	8	hSpCas9	negative selection	2069410
122698616	122698639	7	-	26627737	HCT116	viability after 12 days	GATCAAAGTACTCAGAGACCTGG	RNF133	ENSG00000188050	0.19660810171069953	[112]	[48,115,41]	2	hSpCas9	negative selection	2069411
122697847	122697870	7	+	26627737	HCT116	viability after 15 days	AAGTAGGGTTCTCCTCCACATGG	RNF133	ENSG00000188050	-1.0688372099160783	[231]	[56,89,42]	-8	hSpCas9	negative selection	2151721
122698381	122698404	7	-	26627737	HCT116	viability after 15 days	CATTACAGCCGTGGTTGAGGTGG	RNF133	ENSG00000188050	-0.2951713622884814	[178]	[59,67,119]	-3	hSpCas9	negative selection	2151722
122698390	122698413	7	-	26627737	HCT116	viability after 15 days	GGGAGTTCTCATTACAGCCGTGG	RNF133	ENSG00000188050	0.4205215127405293	[230]	[265,146,130]	4	hSpCas9	negative selection	2151723
122698596	122698619	7	-	26627737	HCT116	viability after 15 days	TGGCTTGCACTTATTGAACGGGG	RNF133	ENSG00000188050	-0.24169651439592443	[1036]	[570,424,522]	-3	hSpCas9	negative selection	2151724
122698597	122698620	7	-	26627737	HCT116	viability after 15 days	CTGGCTTGCACTTATTGAACGGG	RNF133	ENSG00000188050	1.3485132394574126	[442]	[738,594,620]	8	hSpCas9	negative selection	2151725
122698616	122698639	7	-	26627737	HCT116	viability after 15 days	GATCAAAGTACTCAGAGACCTGG	RNF133	ENSG00000188050	0.39863561492932975	[112]	[89,65,100]	4	hSpCas9	negative selection	2151726
122697847	122697870	7	+	26627737	HCT116	viability after 18 days	AAGTAGGGTTCTCCTCCACATGG	RNF133	ENSG00000188050	-1.1030317205673892	[231]	[99,20,36]	-7	hSpCas9	negative selection	2234036
122698381	122698404	7	-	26627737	HCT116	viability after 18 days	CATTACAGCCGTGGTTGAGGTGG	RNF133	ENSG00000188050	0.7801208257984557	[178]	[130,102,217]	6	hSpCas9	negative selection	2234037
122698390	122698413	7	-	26627737	HCT116	viability after 18 days	GGGAGTTCTCATTACAGCCGTGG	RNF133	ENSG00000188050	-0.12343676400198622	[230]	[158,66,82]	-1	hSpCas9	negative selection	2234038
122698596	122698619	7	-	26627737	HCT116	viability after 18 days	TGGCTTGCACTTATTGAACGGGG	RNF133	ENSG00000188050	-0.04201099325530255	[1036]	[564,427,470]	0	hSpCas9	negative selection	2234039
122698597	122698620	7	-	26627737	HCT116	viability after 18 days	CTGGCTTGCACTTATTGAACGGG	RNF133	ENSG00000188050	1.1953761175481805	[442]	[543,445,483]	8	hSpCas9	negative selection	2234040
122698616	122698639	7	-	26627737	HCT116	viability after 18 days	GATCAAAGTACTCAGAGACCTGG	RNF133	ENSG00000188050	-0.9883061057179974	[112]	[26,32,21]	-7	hSpCas9	negative selection	2234041
122698374	122698397	7	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CTTTCTCCCCACCTCAACCACGG	RNF133	ENSG00000188050	-0.08582896679627829	[4,4]	[4,1]	-1	hSpCas9	positive selection	3017161
122698680	122698703	7	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GGAGTTATAGTGCCACCAGAGGG	RNF133	ENSG00000188050	0.17621562712348776	[5,5]	[5,4]	4	hSpCas9	positive selection	3017162
122698390	122698413	7	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GGGAGTTCTCATTACAGCCGTGG	RNF133	ENSG00000188050	0.31050467676610716	[3,3]	[3,3]	6	hSpCas9	positive selection	3017163
122698629	122698652	7	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GTACTTTGATCGGCTGAAAATGG	RNF133	ENSG00000188050	-0.5417615722917736	[2,2]	[0,1]	-7	hSpCas9	positive selection	3017164
122698374	122698397	7	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CTTTCTCCCCACCTCAACCACGG	RNF133	ENSG00000188050	-0.3381800611072141	[4,4]	[1,1]	-5	hSpCas9	positive selection	3085019
122698680	122698703	7	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GGAGTTATAGTGCCACCAGAGGG	RNF133	ENSG00000188050	0.0066974617499295785	[5,5]	[4,2]	0	hSpCas9	positive selection	3085020
122698390	122698413	7	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GGGAGTTCTCATTACAGCCGTGG	RNF133	ENSG00000188050	0.21893037578538396	[3,3]	[2,2]	4	hSpCas9	positive selection	3085021
122698629	122698652	7	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GTACTTTGATCGGCTGAAAATGG	RNF133	ENSG00000188050	0.5611672019957394	[2,2]	[2,2]	8	hSpCas9	positive selection	3085022
122698146	122698169		+	24336571	A375	resistance to PLX after 7 days	ATTACGCAGCTATCCCCATTTGG	RNF133	ENSG00000188050	-0.19402799501719026	[25,26]	[20,23]	-6	hSpCas9	positive selection	3141219
122698593	122698616		-	24336571	A375	resistance to PLX after 7 days	CTTGCACTTATTGAACGGGGAGG	RNF133	ENSG00000188050	0.09072736535440296	[4,3]	[3,4]	3	hSpCas9	positive selection	3141220
122698146	122698169		+	24336571	A375	resistance to PLX after 14 days	ATTACGCAGCTATCCCCATTTGG	RNF133	ENSG00000188050	-0.35779304263065487	[23,20]	[5,9]	-4	hSpCas9	positive selection	3199012
122698593	122698616		-	24336571	A375	resistance to PLX after 14 days	CTTGCACTTATTGAACGGGGAGG	RNF133	ENSG00000188050	-0.13330329330795188	[3,4]	[1,1]	-1	hSpCas9	positive selection	3199013
122698146	122698169		+	24336571	A375	viability after 7 days	ATTACGCAGCTATCCCCATTTGG	RNF133	ENSG00000188050	0.3145500797734069	[21]	[25,26]	5	hSpCas9	negative selection	3256805
122698593	122698616		-	24336571	A375	viability after 7 days	CTTGCACTTATTGAACGGGGAGG	RNF133	ENSG00000188050	-0.22380774179945062	[4]	[4,3]	-3	hSpCas9	negative selection	3256806
122698146	122698169		+	24336571	A375	viability after 14 days	ATTACGCAGCTATCCCCATTTGG	RNF133	ENSG00000188050	0.1107609556816761	[21]	[23,20]	1	hSpCas9	negative selection	3314598
122698593	122698616		-	24336571	A375	viability after 14 days	CTTGCACTTATTGAACGGGGAGG	RNF133	ENSG00000188050	-0.0983851722311837	[4]	[3,4]	-1	hSpCas9	negative selection	3314599
122698237	122698260	7	+	27383988	293T	resistance to West Nile virus (flavivirus)	TTGTTAATCGCTGCCATCTCCGG	RNF133	ENSG00000188050	-2.160526303440063	[683,683]	[0,0]	-9	hSpCas9	positive selection	3390080
122698384	122698407	7	-	27383988	293T	resistance to West Nile virus (flavivirus)	TCTCATTACAGCCGTGGTTGAGG	RNF133	ENSG00000188050	0.41183616050145994	[114,114]	[0,0]	2	hSpCas9	positive selection	3390081
122698598	122698621	7	+	27383988	293T	resistance to West Nile virus (flavivirus)	CCGTTCAATAAGTGCAAGCCAGG	RNF133	ENSG00000188050	-0.19388490038649384	[174,174]	[0,0]	-1	hSpCas9	positive selection	3390082
122698373	122698396	7	+	26780180	HT29	viability (Avana library 4 designs)	CTTTCTCCCCACCTCAACCACGG	RNF133	ENSG00000188050	0.887254901112043	[]	[]	3	hSpCas9	negative selection	3455532
122698680	122698703	7	-	26780180	HT29	viability (Avana library 4 designs)	GGAGTTATAGTGCCACCAGAGGG	RNF133	ENSG00000188050	0.138189177091249	[]	[]	0	hSpCas9	negative selection	3455533
122698390	122698413	7	-	26780180	HT29	viability (Avana library 4 designs)	GGGAGTTCTCATTACAGCCGTGG	RNF133	ENSG00000188050	0.699357425077995	[]	[]	2	hSpCas9	negative selection	3455534
122698628	122698651	7	+	26780180	HT29	viability (Avana library 4 designs)	GTACTTTGATCGGCTGAAAATGG	RNF133	ENSG00000188050	1.53001544771168	[]	[]	6	hSpCas9	negative selection	3455535
122698680	122698703	7	-	26780180	A375	viability (Avana lentiCRISPRv2)	GGAGTTATAGTGCCACCAGAGGG	RNF133	ENSG00000188050	0.547722148013863	[]	[]	0	hSpCas9	negative selection	3553568
122698390	122698413	7	-	26780180	A375	viability (Avana lentiCRISPRv2)	GGGAGTTCTCATTACAGCCGTGG	RNF133	ENSG00000188050	0.520654160868785	[]	[]	0	hSpCas9	negative selection	3553569
122698628	122698651	7	+	26780180	A375	viability (Avana lentiCRISPRv2)	GTACTTTGATCGGCTGAAAATGG	RNF133	ENSG00000188050	-2.98841697517184	[]	[]	-4	hSpCas9	negative selection	3553570
122698373	122698396	7	+	26780180	A375	viability (Avana lentiCRISPRv2)	CTTTCTCCCCACCTCAACCACGG	RNF133	ENSG00000188050	-7.43765929505789	[]	[]	-6	hSpCas9	negative selection	3553571
122698379	122698402	7	-	26780180	A375	viability (Avana lentiCRISPRv2)	TTACAGCCGTGGTTGAGGTGGGG	RNF133	ENSG00000188050	3.52276082132215	[]	[]	5	hSpCas9	negative selection	3553572
122698596	122698619	7	-	26780180	A375	viability (Avana lentiCRISPRv2)	TGGCTTGCACTTATTGAACGGGG	RNF133	ENSG00000188050	2.17773967009489	[]	[]	3	hSpCas9	negative selection	3553573
122698680	122698703	7	-	26780180	A375	viability (Avana lentiGuide)	GGAGTTATAGTGCCACCAGAGGG	RNF133	ENSG00000188050	-2.90497930631106	[]	[]	-5	hSpCas9	negative selection	3662227
122698390	122698413	7	-	26780180	A375	viability (Avana lentiGuide)	GGGAGTTCTCATTACAGCCGTGG	RNF133	ENSG00000188050	-2.63106738178869	[]	[]	-5	hSpCas9	negative selection	3662228
122698628	122698651	7	+	26780180	A375	viability (Avana lentiGuide)	GTACTTTGATCGGCTGAAAATGG	RNF133	ENSG00000188050	-0.491165090004127	[]	[]	0	hSpCas9	negative selection	3662229
122698373	122698396	7	+	26780180	A375	viability (Avana lentiGuide)	CTTTCTCCCCACCTCAACCACGG	RNF133	ENSG00000188050	13.6003994172447	[]	[]	7	hSpCas9	negative selection	3662230
122698379	122698402	7	-	26780180	A375	viability (Avana lentiGuide)	TTACAGCCGTGGTTGAGGTGGGG	RNF133	ENSG00000188050	-0.00208506939246167	[]	[]	0	hSpCas9	negative selection	3662231
122698596	122698619	7	-	26780180	A375	viability (Avana lentiGuide)	TGGCTTGCACTTATTGAACGGGG	RNF133	ENSG00000188050	0.782369209743471	[]	[]	0	hSpCas9	negative selection	3662232
122698680	122698703	7	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGAGTTATAGTGCCACCAGAGGG	RNF133	ENSG00000188050	0.03612367499779845	[6]	[6,6]	0	hSpCas9	positive selection	3770834
122698390	122698413	7	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGGAGTTCTCATTACAGCCGTGG	RNF133	ENSG00000188050	-0.05265432605720019	[4]	[5,2]	-1	hSpCas9	positive selection	3770835
122698628	122698651	7	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GTACTTTGATCGGCTGAAAATGG	RNF133	ENSG00000188050	-0.2667055124246273	[5]	[4,3]	-4	hSpCas9	positive selection	3770836
122698373	122698396	7	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CTTTCTCCCCACCTCAACCACGG	RNF133	ENSG00000188050	-0.3888350966915957	[5]	[3,3]	-5	hSpCas9	positive selection	3770837
122698379	122698402	7	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TTACAGCCGTGGTTGAGGTGGGG	RNF133	ENSG00000188050	0.3408734649541622	[5]	[8,5]	8	hSpCas9	positive selection	3770838
122698596	122698619	7	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TGGCTTGCACTTATTGAACGGGG	RNF133	ENSG00000188050	0.09894312305683137	[5]	[5,5]	2	hSpCas9	positive selection	3770839
122698680	122698703	7	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGAGTTATAGTGCCACCAGAGGG	RNF133	ENSG00000188050	0.21094049643777135	[6]	[6,6]	5	hSpCas9	positive selection	3879441
122698390	122698413	7	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGGAGTTCTCATTACAGCCGTGG	RNF133	ENSG00000188050	0.04884691121498817	[5]	[4,4]	1	hSpCas9	positive selection	3879442
122698628	122698651	7	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GTACTTTGATCGGCTGAAAATGG	RNF133	ENSG00000188050	-0.17490147713477186	[4]	[3,2]	-2	hSpCas9	positive selection	3879443
122698373	122698396	7	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CTTTCTCCCCACCTCAACCACGG	RNF133	ENSG00000188050	0.044715256655858855	[5]	[4,5]	0	hSpCas9	positive selection	3879444
122698379	122698402	7	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TTACAGCCGTGGTTGAGGTGGGG	RNF133	ENSG00000188050	0.26179026704951025	[5]	[5,5]	7	hSpCas9	positive selection	3879445
122698596	122698619	7	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TGGCTTGCACTTATTGAACGGGG	RNF133	ENSG00000188050	0.08154269944897109	[5]	[5,4]	1	hSpCas9	positive selection	3879446
122698146	122698169	7	+	26780180	A375	viability	ATTACGCAGCTATCCCCATTTGG	RNF133	ENSG00000188050	0.113630083357219	[]	[]	0	hSpCas9	negative selection	3989558
122698186	122698209	7	-	26780180	A375	viability	CCAACTTCGAGTAGTAAAAGAGG	RNF133	ENSG00000188050	1.37875703047276	[]	[]	7	hSpCas9	negative selection	3989559
122698598	122698621	7	+	26780180	A375	viability	CCGTTCAATAAGTGCAAGCCAGG	RNF133	ENSG00000188050	0.854239462271758	[]	[]	3	hSpCas9	negative selection	3989560
122698593	122698616	7	-	26780180	A375	viability	CTTGCACTTATTGAACGGGGAGG	RNF133	ENSG00000188050	1.2160236125502	[]	[]	6	hSpCas9	negative selection	3989561
122698384	122698407	7	-	26780180	A375	viability	TCTCATTACAGCCGTGGTTGAGG	RNF133	ENSG00000188050	1.04756178746176	[]	[]	5	hSpCas9	negative selection	3989562
122698237	122698260	7	+	26780180	A375	viability	TTGTTAATCGCTGCCATCTCCGG	RNF133	ENSG00000188050	0.408496878417631	[]	[]	1	hSpCas9	negative selection	3989563
122698146	122698169	7	+	26780180	HT29	viability (GeCKOv2 library)	ATTACGCAGCTATCCCCATTTGG	RNF133	ENSG00000188050	0.23182574808866	[]	[]	0	hSpCas9	negative selection	4097524
122698186	122698209	7	-	26780180	HT29	viability (GeCKOv2 library)	CCAACTTCGAGTAGTAAAAGAGG	RNF133	ENSG00000188050	0.580475074831936	[]	[]	2	hSpCas9	negative selection	4097525
122698598	122698621	7	+	26780180	HT29	viability (GeCKOv2 library)	CCGTTCAATAAGTGCAAGCCAGG	RNF133	ENSG00000188050	1.85076392653216	[]	[]	8	hSpCas9	negative selection	4097526
122698593	122698616	7	-	26780180	HT29	viability (GeCKOv2 library)	CTTGCACTTATTGAACGGGGAGG	RNF133	ENSG00000188050	1.18706205916189	[]	[]	6	hSpCas9	negative selection	4097527
122698384	122698407	7	-	26780180	HT29	viability (GeCKOv2 library)	TCTCATTACAGCCGTGGTTGAGG	RNF133	ENSG00000188050	-0.0678011270279264	[]	[]	-2	hSpCas9	negative selection	4097528
122698237	122698260	7	+	26780180	HT29	viability (GeCKOv2 library)	TTGTTAATCGCTGCCATCTCCGG	RNF133	ENSG00000188050	0.0753481896019659	[]	[]	0	hSpCas9	negative selection	4097529
122698146	122698169	7	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	ATTACGCAGCTATCCCCATTTGG	RNF133	ENSG00000188050	-0.002026619107793559	[4]	[3,2]	0	hSpCas9	positive selection	4166737
122698593	122698616	7	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CTTGCACTTATTGAACGGGGAGG	RNF133	ENSG00000188050	-0.5038656898347401	[1]	[0,0]	-8	hSpCas9	positive selection	4166738
122698146	122698169	7	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	ATTACGCAGCTATCCCCATTTGG	RNF133	ENSG00000188050	0.7744013253108288	[4]	[3,0,1,3]	5	hSpCas9	positive selection	4230759
122698593	122698616	7	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CTTGCACTTATTGAACGGGGAGG	RNF133	ENSG00000188050	1.1959707230715182	[0]	[0,0,0,0]	8	hSpCas9	positive selection	4230760
122698593	122698616	7	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CTTGCACTTATTGAACGGGGAGG	RNF133	ENSG00000188050	-0.022220899456812077	[3]	[2,2]	0	hSpCas9	positive selection	4295139
122698186	122698209	7	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCAACTTCGAGTAGTAAAAGAGG	RNF133	ENSG00000188050	-0.21805418065611626	[1]	[1,0]	-4	hSpCas9	positive selection	4295140
122698146	122698169	7	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ATTACGCAGCTATCCCCATTTGG	RNF133	ENSG00000188050	0.11254197050740175	[3]	[4,2]	2	hSpCas9	positive selection	4295141
122698237	122698260	7	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TTGTTAATCGCTGCCATCTCCGG	RNF133	ENSG00000188050	0.09101446515372796	[4]	[4,3]	1	hSpCas9	positive selection	4359393
122698384	122698407	7	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TCTCATTACAGCCGTGGTTGAGG	RNF133	ENSG00000188050	-0.1259967708686447	[2]	[1,1]	-2	hSpCas9	positive selection	4359394
122698598	122698621	7	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCGTTCAATAAGTGCAAGCCAGG	RNF133	ENSG00000188050	-0.04551258565657689	[2]	[2,1]	-1	hSpCas9	positive selection	4359395
122698390	122698412	7	-	27760321	OCIAML3	viability	GGAGTTCTCATTACAGCCGTGG	RNF133	ENSG00000188050	-0.34853997638914813	[756,703]	[371,548]	-4	hSpCas9	negative selection	4435053
122698527	122698549	7	+	27760321	OCIAML3	viability	TTATAGATGATCACTCCACTGG	RNF133	ENSG00000188050	0.21094210704950234	[115,93]	[107,76]	2	hSpCas9	negative selection	4435054
122698593	122698615	7	-	27760321	OCIAML3	viability	TTGCACTTATTGAACGGGGAGG	RNF133	ENSG00000188050	-0.0065692407859647695	[424,334]	[309,272]	0	hSpCas9	negative selection	4435055
122698681	122698703	7	-	27760321	OCIAML3	viability	GGAGTTATAGTGCCACCAGAGG	RNF133	ENSG00000188050	0.3663304472046622	[521,494]	[540,476]	4	hSpCas9	negative selection	4435056
122698750	122698772	7	-	27760321	OCIAML3	viability	AATCATGTGTTGTCAGAGTTGG	RNF133	ENSG00000188050	-0.045193749066855915	[192,174]	[121,161]	0	hSpCas9	negative selection	4435057
122698390	122698412	7	-	27760321	OCIAML2	viability	GGAGTTCTCATTACAGCCGTGG	RNF133	ENSG00000188050	0.4036284042985182	[756,703]	[620,993]	5	hSpCas9	negative selection	4518516
122698527	122698549	7	+	27760321	OCIAML2	viability	TTATAGATGATCACTCCACTGG	RNF133	ENSG00000188050	0.748539455955511	[115,93]	[169,104]	8	hSpCas9	negative selection	4518517
122698593	122698615	7	-	27760321	OCIAML2	viability	TTGCACTTATTGAACGGGGAGG	RNF133	ENSG00000188050	-0.7126000008726671	[424,334]	[172,203]	-6	hSpCas9	negative selection	4518518
122698681	122698703	7	-	27760321	OCIAML2	viability	GGAGTTATAGTGCCACCAGAGG	RNF133	ENSG00000188050	0.17973063964337882	[521,494]	[421,524]	2	hSpCas9	negative selection	4518519
122698750	122698772	7	-	27760321	OCIAML2	viability	AATCATGTGTTGTCAGAGTTGG	RNF133	ENSG00000188050	0.43767188042130956	[192,174]	[134,288]	6	hSpCas9	negative selection	4518520
122698390	122698412	7	-	27760321	MV411	viability	GGAGTTCTCATTACAGCCGTGG	RNF133	ENSG00000188050	0.6867083160260251	[756,703]	[969,484]	5	hSpCas9	negative selection	4601979
122698527	122698549	7	+	27760321	MV411	viability	TTATAGATGATCACTCCACTGG	RNF133	ENSG00000188050	1.751897091540149	[115,93]	[385,0]	9	hSpCas9	negative selection	4601980
122698593	122698615	7	-	27760321	MV411	viability	TTGCACTTATTGAACGGGGAGG	RNF133	ENSG00000188050	0.41679950024782886	[424,334]	[336,325]	3	hSpCas9	negative selection	4601981
122698681	122698703	7	-	27760321	MV411	viability	GGAGTTATAGTGCCACCAGAGG	RNF133	ENSG00000188050	-0.32831466639788043	[521,494]	[215,344]	-2	hSpCas9	negative selection	4601982
122698750	122698772	7	-	27760321	MV411	viability	AATCATGTGTTGTCAGAGTTGG	RNF133	ENSG00000188050	1.875961903240999	[192,174]	[382,538]	9	hSpCas9	negative selection	4601983
122698390	122698412	7	-	27760321	HL60	viability	GGAGTTCTCATTACAGCCGTGG	RNF133	ENSG00000188050	0.05592826933794759	[756,703]	[686,549]	0	hSpCas9	negative selection	4685442
122698527	122698549	7	+	27760321	HL60	viability	TTATAGATGATCACTCCACTGG	RNF133	ENSG00000188050	-0.6109545426056568	[115,93]	[100,7]	-6	hSpCas9	negative selection	4685443
122698593	122698615	7	-	27760321	HL60	viability	TTGCACTTATTGAACGGGGAGG	RNF133	ENSG00000188050	0.4714944818184301	[424,334]	[431,422]	6	hSpCas9	negative selection	4685444
122698681	122698703	7	-	27760321	HL60	viability	GGAGTTATAGTGCCACCAGAGG	RNF133	ENSG00000188050	0.32155039435593386	[521,494]	[491,548]	4	hSpCas9	negative selection	4685445
122698750	122698772	7	-	27760321	HL60	viability	AATCATGTGTTGTCAGAGTTGG	RNF133	ENSG00000188050	0.1484080308878135	[192,174]	[181,149]	1	hSpCas9	negative selection	4685446
122698390	122698412	7	-	27760321	HT1080	viability	GGAGTTCTCATTACAGCCGTGG	RNF133	ENSG00000188050	1.2463949430950922	[703,549]	[900,254]	6	hSpCas9	negative selection	4768905
122698527	122698549	7	+	27760321	HT1080	viability	TTATAGATGATCACTCCACTGG	RNF133	ENSG00000188050	1.638209728933215	[93,73]	[150,52]	8	hSpCas9	negative selection	4768906
122698593	122698615	7	-	27760321	HT1080	viability	TTGCACTTATTGAACGGGGAGG	RNF133	ENSG00000188050	-0.5564661081967333	[334,261]	[56,106]	-2	hSpCas9	negative selection	4768907
122698681	122698703	7	-	27760321	HT1080	viability	GGAGTTATAGTGCCACCAGAGG	RNF133	ENSG00000188050	0.4277936523258288	[494,385]	[257,211]	2	hSpCas9	negative selection	4768908
122698750	122698772	7	-	27760321	HT1080	viability	AATCATGTGTTGTCAGAGTTGG	RNF133	ENSG00000188050	-0.7769445306255272	[174,136]	[20,52]	-3	hSpCas9	negative selection	4768909
122698390	122698412	7	-	27760321	HT29	viability after 7 days	GGAGTTCTCATTACAGCCGTGG	RNF133	ENSG00000188050	0.2633983847758288	[703,549]	[1044,1101,771]	4	hSpCas9	negative selection	4852368
122698527	122698549	7	+	27760321	HT29	viability after 7 days	TTATAGATGATCACTCCACTGG	RNF133	ENSG00000188050	-0.5650593209587438	[93,73]	[147,49,32]	-7	hSpCas9	negative selection	4852369
122698593	122698615	7	-	27760321	HT29	viability after 7 days	TTGCACTTATTGAACGGGGAGG	RNF133	ENSG00000188050	-0.18140972687981732	[334,261]	[367,243,404]	-3	hSpCas9	negative selection	4852370
122698681	122698703	7	-	27760321	HT29	viability after 7 days	GGAGTTATAGTGCCACCAGAGG	RNF133	ENSG00000188050	0.3428430724221717	[494,385]	[873,554,745]	5	hSpCas9	negative selection	4852371
122698750	122698772	7	-	27760321	HT29	viability after 7 days	AATCATGTGTTGTCAGAGTTGG	RNF133	ENSG00000188050	0.017630342592244386	[174,136]	[208,172,226]	0	hSpCas9	negative selection	4852372
122698390	122698412	7	-	27760321	HT29	viability after 25 days	GGAGTTCTCATTACAGCCGTGG	RNF133	ENSG00000188050	0.2809206863689535	[703,549]	[765,740,1137]	3	hSpCas9	negative selection	4935831
122698527	122698549	7	+	27760321	HT29	viability after 25 days	TTATAGATGATCACTCCACTGG	RNF133	ENSG00000188050	-0.2329453378849653	[93,73]	[84,50,111]	-2	hSpCas9	negative selection	4935832
122698593	122698615	7	-	27760321	HT29	viability after 25 days	TTGCACTTATTGAACGGGGAGG	RNF133	ENSG00000188050	0.08836532985083784	[334,261]	[356,462,256]	0	hSpCas9	negative selection	4935833
122698681	122698703	7	-	27760321	HT29	viability after 25 days	GGAGTTATAGTGCCACCAGAGG	RNF133	ENSG00000188050	0.08630644707125229	[494,385]	[372,632,614]	0	hSpCas9	negative selection	4935834
122698750	122698772	7	-	27760321	HT29	viability after 25 days	AATCATGTGTTGTCAGAGTTGG	RNF133	ENSG00000188050	-0.6389926663916157	[174,136]	[107,144,87]	-5	hSpCas9	negative selection	4935835
122698390	122698412	7	-	27760321	HT29	viability after 22 days	GGAGTTCTCATTACAGCCGTGG	RNF133	ENSG00000188050	0.001016397422758053	[703,549]	[509,840,831]	0	hSpCas9	negative selection	5019294
122698527	122698549	7	+	27760321	HT29	viability after 22 days	TTATAGATGATCACTCCACTGG	RNF133	ENSG00000188050	0.54027407048886	[93,73]	[64,108,252]	6	hSpCas9	negative selection	5019295
122698593	122698615	7	-	27760321	HT29	viability after 22 days	TTGCACTTATTGAACGGGGAGG	RNF133	ENSG00000188050	0.20004739302319502	[334,261]	[324,499,365]	2	hSpCas9	negative selection	5019296
122698681	122698703	7	-	27760321	HT29	viability after 22 days	GGAGTTATAGTGCCACCAGAGG	RNF133	ENSG00000188050	0.4029454452351856	[494,385]	[844,515,653]	4	hSpCas9	negative selection	5019297
122698750	122698772	7	-	27760321	HT29	viability after 22 days	AATCATGTGTTGTCAGAGTTGG	RNF133	ENSG00000188050	-0.8326445005164111	[174,136]	[27,157,119]	-6	hSpCas9	negative selection	5019298
122698390	122698412	7	-	27760321	HT29	viability after 19 days	GGAGTTCTCATTACAGCCGTGG	RNF133	ENSG00000188050	0.030177434099856515	[703,549]	[958,686,579]	0	hSpCas9	negative selection	5102757
122698527	122698549	7	+	27760321	HT29	viability after 19 days	TTATAGATGATCACTCCACTGG	RNF133	ENSG00000188050	-0.15029013154219184	[93,73]	[195,62,14]	-1	hSpCas9	negative selection	5102758
122698593	122698615	7	-	27760321	HT29	viability after 19 days	TTGCACTTATTGAACGGGGAGG	RNF133	ENSG00000188050	-0.014844964389376436	[334,261]	[448,473,110]	0	hSpCas9	negative selection	5102759
122698681	122698703	7	-	27760321	HT29	viability after 19 days	GGAGTTATAGTGCCACCAGAGG	RNF133	ENSG00000188050	-0.15221851760286814	[494,385]	[649,484,252]	-1	hSpCas9	negative selection	5102760
122698750	122698772	7	-	27760321	HT29	viability after 19 days	AATCATGTGTTGTCAGAGTTGG	RNF133	ENSG00000188050	0.6250685624989132	[174,136]	[199,272,341]	6	hSpCas9	negative selection	5102761
122698390	122698412	7	-	27760321	HT29	viability after 16 days	GGAGTTCTCATTACAGCCGTGG	RNF133	ENSG00000188050	0.4694017189889823	[703,549]	[1080,936,906]	5	hSpCas9	negative selection	5186220
122698527	122698549	7	+	27760321	HT29	viability after 16 days	TTATAGATGATCACTCCACTGG	RNF133	ENSG00000188050	-0.5461487173316866	[93,73]	[21,70,95]	-5	hSpCas9	negative selection	5186221
122698593	122698615	7	-	27760321	HT29	viability after 16 days	TTGCACTTATTGAACGGGGAGG	RNF133	ENSG00000188050	0.06055371061879339	[334,261]	[330,358,352]	0	hSpCas9	negative selection	5186222
122698681	122698703	7	-	27760321	HT29	viability after 16 days	GGAGTTATAGTGCCACCAGAGG	RNF133	ENSG00000188050	0.6023847787063049	[494,385]	[726,688,827]	7	hSpCas9	negative selection	5186223
122698750	122698772	7	-	27760321	HT29	viability after 16 days	AATCATGTGTTGTCAGAGTTGG	RNF133	ENSG00000188050	-0.29971696379385193	[174,136]	[250,93,91]	-3	hSpCas9	negative selection	5186224
122698390	122698412	7	-	27760321	HT29	viability after 13 days	GGAGTTCTCATTACAGCCGTGG	RNF133	ENSG00000188050	0.33565567711950406	[703,549]	[1023,972,765]	4	hSpCas9	negative selection	5269683
122698527	122698549	7	+	27760321	HT29	viability after 13 days	TTATAGATGATCACTCCACTGG	RNF133	ENSG00000188050	-0.42619416754277717	[93,73]	[6,55,149]	-5	hSpCas9	negative selection	5269684
122698593	122698615	7	-	27760321	HT29	viability after 13 days	TTGCACTTATTGAACGGGGAGG	RNF133	ENSG00000188050	0.2064109303945625	[334,261]	[341,339,509]	2	hSpCas9	negative selection	5269685
122698681	122698703	7	-	27760321	HT29	viability after 13 days	GGAGTTATAGTGCCACCAGAGG	RNF133	ENSG00000188050	0.40093282283447473	[494,385]	[782,723,525]	5	hSpCas9	negative selection	5269686
122698750	122698772	7	-	27760321	HT29	viability after 13 days	AATCATGTGTTGTCAGAGTTGG	RNF133	ENSG00000188050	-0.39227941003885536	[174,136]	[119,227,69]	-4	hSpCas9	negative selection	5269687
122698390	122698412	7	-	27760321	HT29	viability after 10 days	GGAGTTCTCATTACAGCCGTGG	RNF133	ENSG00000188050	0.2701578887227196	[703,549]	[694,870,1256]	3	hSpCas9	negative selection	5353146
122698527	122698549	7	+	27760321	HT29	viability after 10 days	TTATAGATGATCACTCCACTGG	RNF133	ENSG00000188050	0.4395854288315566	[93,73]	[179,86,157]	6	hSpCas9	negative selection	5353147
122698593	122698615	7	-	27760321	HT29	viability after 10 days	TTGCACTTATTGAACGGGGAGG	RNF133	ENSG00000188050	-0.1020421387340566	[334,261]	[302,390,348]	-1	hSpCas9	negative selection	5353148
122698681	122698703	7	-	27760321	HT29	viability after 10 days	GGAGTTATAGTGCCACCAGAGG	RNF133	ENSG00000188050	-0.030269630343053522	[494,385]	[620,510,483]	0	hSpCas9	negative selection	5353149
122698750	122698772	7	-	27760321	HT29	viability after 10 days	AATCATGTGTTGTCAGAGTTGG	RNF133	ENSG00000188050	-0.7650366500523824	[174,136]	[69,176,98]	-7	hSpCas9	negative selection	5353150
122698390	122698412	7	-	27760321	MOLM13	viability	GGAGTTCTCATTACAGCCGTGG	RNF133	ENSG00000188050	1.3310243854749135	[756,703]	[1121,964]	8	hSpCas9	negative selection	5436609
122698527	122698549	7	+	27760321	MOLM13	viability	TTATAGATGATCACTCCACTGG	RNF133	ENSG00000188050	0.02819253902154717	[115,93]	[31,83]	0	hSpCas9	negative selection	5436610
122698593	122698615	7	-	27760321	MOLM13	viability	TTGCACTTATTGAACGGGGAGG	RNF133	ENSG00000188050	0.43707124866216895	[424,334]	[188,372]	3	hSpCas9	negative selection	5436611
122698681	122698703	7	-	27760321	MOLM13	viability	GGAGTTATAGTGCCACCAGAGG	RNF133	ENSG00000188050	1.7958920584519256	[521,494]	[1201,822]	9	hSpCas9	negative selection	5436612
122698750	122698772	7	-	27760321	MOLM13	viability	AATCATGTGTTGTCAGAGTTGG	RNF133	ENSG00000188050	1.1328112277402904	[192,174]	[368,106]	7	hSpCas9	negative selection	5436613
122698628	122698651	7	+	27661255	K562	viability	GTACTTTGATCGGCTGAAAATGG	RNF133	ENSG00000188050	0.01783434895439151	[2634,2645]	[2367,1936]	0	dCas9-KRAB	negative selection	5507805
122698665	122698688	7	+	27661255	K562	viability	GCATTTTGGATTTTTCCCTCTGG	RNF133	ENSG00000188050	0.14376276119373005	[941,1043]	[1013,755]	5	dCas9-KRAB	negative selection	5507806
122698856	122698879	7	+	27661255	K562	viability	GAACTTCATAAGCCAGGAAGAGG	RNF133	ENSG00000188050	0.10144989260612788	[773,888]	[780,650]	3	dCas9-KRAB	negative selection	5507807
122698899	122698922	7	-	27661255	K562	viability	GAGATGCATCTACTCAAGGTTGG	RNF133	ENSG00000188050	0.23017042420482275	[508,697]	[632,501]	7	dCas9-KRAB	negative selection	5507808
122698903	122698926	7	-	27661255	K562	viability	GAGAGAGATGCATCTACTCAAGG	RNF133	ENSG00000188050	0.03833853965700973	[1634,1699]	[1516,1238]	1	dCas9-KRAB	negative selection	5507809
122698593	122698616	7	-	27260156	BXPC3	viability	CTTGCACTTATTGAACGGGGAGG	RNF133	ENSG00000188050	-0.31264855861112706	[759]	[515,559,877,620]	-6	hSpCas9	negative selection	5567599
122698186	122698209	7	-	27260156	BXPC3	viability	CCAACTTCGAGTAGTAAAAGAGG	RNF133	ENSG00000188050	0.08200069261925691	[188]	[220,169,225,220]	1	hSpCas9	negative selection	5567600
122698146	122698169	7	+	27260156	BXPC3	viability	ATTACGCAGCTATCCCCATTTGG	RNF133	ENSG00000188050	0.326379863344469	[800]	[777,944,1154,1395]	7	hSpCas9	negative selection	5567601
122698237	122698260	7	+	27260156	BXPC3	viability	TTGTTAATCGCTGCCATCTCCGG	RNF133	ENSG00000188050	0.25241905881029436	[1579]	[1718,1852,2190,2155]	5	hSpCas9	negative selection	5631853
122698384	122698407	7	-	27260156	BXPC3	viability	TCTCATTACAGCCGTGGTTGAGG	RNF133	ENSG00000188050	-0.13959172043231116	[261]	[220,270,226,278]	-3	hSpCas9	negative selection	5631854
122698598	122698621	7	+	27260156	BXPC3	viability	CCGTTCAATAAGTGCAAGCCAGG	RNF133	ENSG00000188050	0.26685593817622755	[428]	[466,526,567,610]	6	hSpCas9	negative selection	5631855
122698593	122698616	7	-	27260156	A673	viability	CTTGCACTTATTGAACGGGGAGG	RNF133	ENSG00000188050	-0.09104404861486504	[759]	[976,785,723,960]	-2	hSpCas9	negative selection	5688850
122698186	122698209	7	-	27260156	A673	viability	CCAACTTCGAGTAGTAAAAGAGG	RNF133	ENSG00000188050	-0.11700992803708754	[188]	[223,156,209,250]	-3	hSpCas9	negative selection	5688851
122698146	122698169	7	+	27260156	A673	viability	ATTACGCAGCTATCCCCATTTGG	RNF133	ENSG00000188050	0.15494447740792405	[800]	[1210,1050,977,1057]	3	hSpCas9	negative selection	5688852
122698237	122698260	7	+	27260156	A673	viability	TTGTTAATCGCTGCCATCTCCGG	RNF133	ENSG00000188050	0.24952243934963714	[1579]	[2498,1960,2292,2301]	6	hSpCas9	negative selection	5753104
122698384	122698407	7	-	27260156	A673	viability	TCTCATTACAGCCGTGGTTGAGG	RNF133	ENSG00000188050	-0.050428946884528925	[261]	[334,318,305,254]	-1	hSpCas9	negative selection	5753105
122698598	122698621	7	+	27260156	A673	viability	CCGTTCAATAAGTGCAAGCCAGG	RNF133	ENSG00000188050	-0.010165506755483139	[428]	[503,549,468,520]	0	hSpCas9	negative selection	5753106
122698593	122698616	7	-	27260156	A375	viability	CTTGCACTTATTGAACGGGGAGG	RNF133	ENSG00000188050	-0.1743111482910712	[759]	[986,513,864,745]	-3	hSpCas9	negative selection	5810101
122698186	122698209	7	-	27260156	A375	viability	CCAACTTCGAGTAGTAAAAGAGG	RNF133	ENSG00000188050	-0.09833033869285379	[188]	[340,148,64,255]	-1	hSpCas9	negative selection	5810102
122698146	122698169	7	+	27260156	A375	viability	ATTACGCAGCTATCCCCATTTGG	RNF133	ENSG00000188050	0.4705966951677085	[800]	[1355,1145,1379,1279]	7	hSpCas9	negative selection	5810103
122698237	122698260	7	+	27260156	A375	viability	TTGTTAATCGCTGCCATCTCCGG	RNF133	ENSG00000188050	0.2469612575687441	[1579]	[2026,2062,2096,2506]	3	hSpCas9	negative selection	5874355
122698384	122698407	7	-	27260156	A375	viability	TCTCATTACAGCCGTGGTTGAGG	RNF133	ENSG00000188050	-0.08383395804256355	[261]	[375,324,275,193]	-1	hSpCas9	negative selection	5874356
122698598	122698621	7	+	27260156	A375	viability	CCGTTCAATAAGTGCAAGCCAGG	RNF133	ENSG00000188050	0.284618180268975	[428]	[733,643,607,474]	4	hSpCas9	negative selection	5874357
122698593	122698616	7	-	27260156	COLO741	viability	CTTGCACTTATTGAACGGGGAGG	RNF133	ENSG00000188050	-0.23719934459637754	[759]	[791,822,849]	-5	hSpCas9	negative selection	5931352
122698186	122698209	7	-	27260156	COLO741	viability	CCAACTTCGAGTAGTAAAAGAGG	RNF133	ENSG00000188050	-0.19744562460445336	[188]	[299,145,193]	-4	hSpCas9	negative selection	5931353
122698146	122698169	7	+	27260156	COLO741	viability	ATTACGCAGCTATCCCCATTTGG	RNF133	ENSG00000188050	0.4434425385833467	[800]	[1444,1820,944]	8	hSpCas9	negative selection	5931354
122698237	122698260	7	+	27260156	COLO741	viability	TTGTTAATCGCTGCCATCTCCGG	RNF133	ENSG00000188050	0.07794548389263944	[1579]	[2478,1826,2111]	1	hSpCas9	negative selection	5995606
122698384	122698407	7	-	27260156	COLO741	viability	TCTCATTACAGCCGTGGTTGAGG	RNF133	ENSG00000188050	0.220451528660369	[261]	[396,343,425]	4	hSpCas9	negative selection	5995607
122698598	122698621	7	+	27260156	COLO741	viability	CCGTTCAATAAGTGCAAGCCAGG	RNF133	ENSG00000188050	-0.023609286092511644	[428]	[696,510,429]	0	hSpCas9	negative selection	5995608
122698593	122698616	7	-	27260156	CAL120	viability	CTTGCACTTATTGAACGGGGAGG	RNF133	ENSG00000188050	0.1365805134868634	[759]	[1228,990,928]	2	hSpCas9	negative selection	6052603
122698186	122698209	7	-	27260156	CAL120	viability	CCAACTTCGAGTAGTAAAAGAGG	RNF133	ENSG00000188050	0.6150917945834415	[188]	[479,338,280]	8	hSpCas9	negative selection	6052604
122698146	122698169	7	+	27260156	CAL120	viability	ATTACGCAGCTATCCCCATTTGG	RNF133	ENSG00000188050	0.5605993082842764	[800]	[2210,1334,983]	8	hSpCas9	negative selection	6052605
122698237	122698260	7	+	27260156	CAL120	viability	TTGTTAATCGCTGCCATCTCCGG	RNF133	ENSG00000188050	0.5723804473238008	[1579]	[4585,1807,2630]	8	hSpCas9	negative selection	6116857
122698384	122698407	7	-	27260156	CAL120	viability	TCTCATTACAGCCGTGGTTGAGG	RNF133	ENSG00000188050	-0.09551334672121814	[261]	[258,323,324]	-1	hSpCas9	negative selection	6116858
122698598	122698621	7	+	27260156	CAL120	viability	CCGTTCAATAAGTGCAAGCCAGG	RNF133	ENSG00000188050	0.5768867915438702	[428]	[950,841,621]	8	hSpCas9	negative selection	6116859
122698593	122698616	7	-	27260156	CADOES1	viability	CTTGCACTTATTGAACGGGGAGG	RNF133	ENSG00000188050	-0.2662251978018992	[759]	[635,608,565,537]	-4	hSpCas9	negative selection	6173854
122698186	122698209	7	-	27260156	CADOES1	viability	CCAACTTCGAGTAGTAAAAGAGG	RNF133	ENSG00000188050	0.0587920525067962	[188]	[181,194,156,198]	1	hSpCas9	negative selection	6173855
122698146	122698169	7	+	27260156	CADOES1	viability	ATTACGCAGCTATCCCCATTTGG	RNF133	ENSG00000188050	0.3305598987104861	[800]	[691,1196,779,1084]	5	hSpCas9	negative selection	6173856
122698237	122698260	7	+	27260156	CADOES1	viability	TTGTTAATCGCTGCCATCTCCGG	RNF133	ENSG00000188050	0.2747104557767861	[1579]	[1687,1685,1904,1833]	4	hSpCas9	negative selection	6238108
122698384	122698407	7	-	27260156	CADOES1	viability	TCTCATTACAGCCGTGGTTGAGG	RNF133	ENSG00000188050	-0.019008916029683576	[261]	[258,184,245,272]	0	hSpCas9	negative selection	6238109
122698598	122698621	7	+	27260156	CADOES1	viability	CCGTTCAATAAGTGCAAGCCAGG	RNF133	ENSG00000188050	0.4013952451971541	[428]	[566,501,582,452]	6	hSpCas9	negative selection	6238110
122698593	122698616	7	-	27260156	EWS502	viability	CTTGCACTTATTGAACGGGGAGG	RNF133	ENSG00000188050	-0.06803653859037384	[759]	[583,912,687,908]	-1	hSpCas9	negative selection	6295105
122698186	122698209	7	-	27260156	EWS502	viability	CCAACTTCGAGTAGTAAAAGAGG	RNF133	ENSG00000188050	-0.5033210854092733	[188]	[130,96,137,205]	-7	hSpCas9	negative selection	6295106
122698146	122698169	7	+	27260156	EWS502	viability	ATTACGCAGCTATCCCCATTTGG	RNF133	ENSG00000188050	0.4804457791697514	[800]	[1076,1181,1361,1119]	8	hSpCas9	negative selection	6295107
122698237	122698260	7	+	27260156	EWS502	viability	TTGTTAATCGCTGCCATCTCCGG	RNF133	ENSG00000188050	0.4235832245316187	[1579]	[1896,2434,2616,2045]	7	hSpCas9	negative selection	6359359
122698384	122698407	7	-	27260156	EWS502	viability	TCTCATTACAGCCGTGGTTGAGG	RNF133	ENSG00000188050	0.17619522981090785	[261]	[233,352,275,403]	3	hSpCas9	negative selection	6359360
122698598	122698621	7	+	27260156	EWS502	viability	CCGTTCAATAAGTGCAAGCCAGG	RNF133	ENSG00000188050	0.03671980550046851	[428]	[455,375,569,466]	0	hSpCas9	negative selection	6359361
122698593	122698616	7	-	27260156	EW8	viability	CTTGCACTTATTGAACGGGGAGG	RNF133	ENSG00000188050	-0.10360299671691708	[759]	[672,563,407,684]	-2	hSpCas9	negative selection	6416356
122698186	122698209	7	-	27260156	EW8	viability	CCAACTTCGAGTAGTAAAAGAGG	RNF133	ENSG00000188050	-0.11413281952884535	[188]	[132,147,181,94]	-2	hSpCas9	negative selection	6416357
122698146	122698169	7	+	27260156	EW8	viability	ATTACGCAGCTATCCCCATTTGG	RNF133	ENSG00000188050	0.26284524416256927	[800]	[926,726,775,699]	5	hSpCas9	negative selection	6416358
122698237	122698260	7	+	27260156	EW8	viability	TTGTTAATCGCTGCCATCTCCGG	RNF133	ENSG00000188050	0.4486608890535335	[1579]	[1889,1959,1409,1798]	7	hSpCas9	negative selection	6480610
122698384	122698407	7	-	27260156	EW8	viability	TCTCATTACAGCCGTGGTTGAGG	RNF133	ENSG00000188050	-0.15920298047868497	[261]	[249,236,82,214]	-3	hSpCas9	negative selection	6480611
122698598	122698621	7	+	27260156	EW8	viability	CCGTTCAATAAGTGCAAGCCAGG	RNF133	ENSG00000188050	0.16415045694952496	[428]	[542,384,313,344]	3	hSpCas9	negative selection	6480612
122698593	122698616	7	-	27260156	CORL105	viability	CTTGCACTTATTGAACGGGGAGG	RNF133	ENSG00000188050	-0.15212613765685445	[759]	[838,830,822,713]	-3	hSpCas9	negative selection	6537607
122698186	122698209	7	-	27260156	CORL105	viability	CCAACTTCGAGTAGTAAAAGAGG	RNF133	ENSG00000188050	0.35248954690194645	[188]	[334,293,327,181]	6	hSpCas9	negative selection	6537608
122698146	122698169	7	+	27260156	CORL105	viability	ATTACGCAGCTATCCCCATTTGG	RNF133	ENSG00000188050	0.30042323554894046	[800]	[1004,1189,1457,1007]	5	hSpCas9	negative selection	6537609
122698237	122698260	7	+	27260156	CORL105	viability	TTGTTAATCGCTGCCATCTCCGG	RNF133	ENSG00000188050	0.3617932653114153	[1579]	[2225,2194,2803,2346]	6	hSpCas9	negative selection	6601861
122698384	122698407	7	-	27260156	CORL105	viability	TCTCATTACAGCCGTGGTTGAGG	RNF133	ENSG00000188050	0.19450911278082184	[261]	[358,315,402,334]	3	hSpCas9	negative selection	6601862
122698598	122698621	7	+	27260156	CORL105	viability	CCGTTCAATAAGTGCAAGCCAGG	RNF133	ENSG00000188050	0.23980987372221044	[428]	[551,430,774,643]	4	hSpCas9	negative selection	6601863
122698593	122698616	7	-	27260156	HS294T	viability	CTTGCACTTATTGAACGGGGAGG	RNF133	ENSG00000188050	0.4133257916616795	[759]	[411,496,289,352]	5	hSpCas9	negative selection	6658858
122698186	122698209	7	-	27260156	HS294T	viability	CCAACTTCGAGTAGTAAAAGAGG	RNF133	ENSG00000188050	0.020114155043134962	[188]	[46,67,119,61]	0	hSpCas9	negative selection	6658859
122698146	122698169	7	+	27260156	HS294T	viability	ATTACGCAGCTATCCCCATTTGG	RNF133	ENSG00000188050	0.5436187424494447	[800]	[285,517,522,498]	7	hSpCas9	negative selection	6658860
122698237	122698260	7	+	27260156	HS294T	viability	TTGTTAATCGCTGCCATCTCCGG	RNF133	ENSG00000188050	0.3216319155600551	[1579]	[717,662,695,1025]	4	hSpCas9	negative selection	6723112
122698384	122698407	7	-	27260156	HS294T	viability	TCTCATTACAGCCGTGGTTGAGG	RNF133	ENSG00000188050	-0.03143509356065499	[261]	[93,121,79,99]	0	hSpCas9	negative selection	6723113
122698598	122698621	7	+	27260156	HS294T	viability	CCGTTCAATAAGTGCAAGCCAGG	RNF133	ENSG00000188050	-0.16110307795183215	[428]	[160,126,122,187]	-2	hSpCas9	negative selection	6723114
122698593	122698616	7	-	27260156	HCC44	viability	CTTGCACTTATTGAACGGGGAGG	RNF133	ENSG00000188050	0.11054586412385436	[759]	[978,922,1056,777]	1	hSpCas9	negative selection	6780109
122698186	122698209	7	-	27260156	HCC44	viability	CCAACTTCGAGTAGTAAAAGAGG	RNF133	ENSG00000188050	0.5785218304264589	[188]	[231,408,322,290]	8	hSpCas9	negative selection	6780110
122698146	122698169	7	+	27260156	HCC44	viability	ATTACGCAGCTATCCCCATTTGG	RNF133	ENSG00000188050	0.1457582777846912	[800]	[973,731,1357,1032]	2	hSpCas9	negative selection	6780111
122698237	122698260	7	+	27260156	HCC44	viability	TTGTTAATCGCTGCCATCTCCGG	RNF133	ENSG00000188050	0.4186541157288979	[1579]	[2474,1994,2732,2452]	7	hSpCas9	negative selection	6844363
122698384	122698407	7	-	27260156	HCC44	viability	TCTCATTACAGCCGTGGTTGAGG	RNF133	ENSG00000188050	0.2618055438256712	[261]	[385,327,385,330]	4	hSpCas9	negative selection	6844364
122698598	122698621	7	+	27260156	HCC44	viability	CCGTTCAATAAGTGCAAGCCAGG	RNF133	ENSG00000188050	0.39373834108935113	[428]	[846,480,724,550]	6	hSpCas9	negative selection	6844365
122698593	122698616	7	-	27260156	G402	viability	CTTGCACTTATTGAACGGGGAGG	RNF133	ENSG00000188050	-0.6217322862904731	[759]	[711,522,485,693]	-6	hSpCas9	negative selection	6901360
122698186	122698209	7	-	27260156	G402	viability	CCAACTTCGAGTAGTAAAAGAGG	RNF133	ENSG00000188050	0.30316765270972135	[188]	[371,328,223,229]	4	hSpCas9	negative selection	6901361
122698146	122698169	7	+	27260156	G402	viability	ATTACGCAGCTATCCCCATTTGG	RNF133	ENSG00000188050	0.618148998442702	[800]	[1555,1489,1765,1204]	7	hSpCas9	negative selection	6901362
122698237	122698260	7	+	27260156	G402	viability	TTGTTAATCGCTGCCATCTCCGG	RNF133	ENSG00000188050	0.6453693318433495	[1579]	[3546,4020,2521,2138]	7	hSpCas9	negative selection	6965614
122698384	122698407	7	-	27260156	G402	viability	TCTCATTACAGCCGTGGTTGAGG	RNF133	ENSG00000188050	0.6890544572383203	[261]	[341,709,479,513]	8	hSpCas9	negative selection	6965615
122698598	122698621	7	+	27260156	G402	viability	CCGTTCAATAAGTGCAAGCCAGG	RNF133	ENSG00000188050	0.030208313107872142	[428]	[758,377,563,461]	0	hSpCas9	negative selection	6965616
122698593	122698616	7	-	27260156	L33	viability	CTTGCACTTATTGAACGGGGAGG	RNF133	ENSG00000188050	0.02542318060893145	[759]	[793,304,467,809]	0	hSpCas9	negative selection	7022611
122698186	122698209	7	-	27260156	L33	viability	CCAACTTCGAGTAGTAAAAGAGG	RNF133	ENSG00000188050	0.3795621677808234	[188]	[290,85,161,223]	7	hSpCas9	negative selection	7022612
122698146	122698169	7	+	27260156	L33	viability	ATTACGCAGCTATCCCCATTTGG	RNF133	ENSG00000188050	0.20749584479832284	[800]	[919,384,532,990]	4	hSpCas9	negative selection	7022613
122698237	122698260	7	+	27260156	L33	viability	TTGTTAATCGCTGCCATCTCCGG	RNF133	ENSG00000188050	0.021929942621608634	[1579]	[1650,649,936,1685]	0	hSpCas9	negative selection	7086865
122698384	122698407	7	-	27260156	L33	viability	TCTCATTACAGCCGTGGTTGAGG	RNF133	ENSG00000188050	0.3876763182626286	[261]	[350,148,176,373]	7	hSpCas9	negative selection	7086866
122698598	122698621	7	+	27260156	L33	viability	CCGTTCAATAAGTGCAAGCCAGG	RNF133	ENSG00000188050	0.08271366374846086	[428]	[477,177,208,569]	1	hSpCas9	negative selection	7086867
122698593	122698616	7	-	27260156	K562	viability	CTTGCACTTATTGAACGGGGAGG	RNF133	ENSG00000188050	-0.438894730838644	[759]	[358,474,676,467]	-5	hSpCas9	negative selection	7143862
122698186	122698209	7	-	27260156	K562	viability	CCAACTTCGAGTAGTAAAAGAGG	RNF133	ENSG00000188050	0.5148703434462989	[188]	[447,345,66,131]	6	hSpCas9	negative selection	7143863
122698146	122698169	7	+	27260156	K562	viability	ATTACGCAGCTATCCCCATTTGG	RNF133	ENSG00000188050	0.43016398602264827	[800]	[1400,787,713,951]	5	hSpCas9	negative selection	7143864
122698237	122698260	7	+	27260156	K562	viability	TTGTTAATCGCTGCCATCTCCGG	RNF133	ENSG00000188050	0.44698211323114356	[1579]	[2164,1581,2342,1588]	5	hSpCas9	negative selection	7208116
122698384	122698407	7	-	27260156	K562	viability	TCTCATTACAGCCGTGGTTGAGG	RNF133	ENSG00000188050	-0.20537938627767094	[261]	[277,295,135,116]	-3	hSpCas9	negative selection	7208117
122698598	122698621	7	+	27260156	K562	viability	CCGTTCAATAAGTGCAAGCCAGG	RNF133	ENSG00000188050	-0.10183099460394027	[428]	[603,185,377,270]	-1	hSpCas9	negative selection	7208118
122698593	122698616	7	-	27260156	HT29	viability	CTTGCACTTATTGAACGGGGAGG	RNF133	ENSG00000188050	0.004018827941615677	[759]	[992,1179,833,741]	0	hSpCas9	negative selection	7265113
122698186	122698209	7	-	27260156	HT29	viability	CCAACTTCGAGTAGTAAAAGAGG	RNF133	ENSG00000188050	0.06704509234282319	[188]	[243,258,229,230]	1	hSpCas9	negative selection	7265114
122698146	122698169	7	+	27260156	HT29	viability	ATTACGCAGCTATCCCCATTTGG	RNF133	ENSG00000188050	0.36114832216184456	[800]	[1404,1332,1198,1094]	7	hSpCas9	negative selection	7265115
122698237	122698260	7	+	27260156	HT29	viability	TTGTTAATCGCTGCCATCTCCGG	RNF133	ENSG00000188050	0.30067604419244076	[1579]	[2546,2419,2631,1920]	6	hSpCas9	negative selection	7329367
122698384	122698407	7	-	27260156	HT29	viability	TCTCATTACAGCCGTGGTTGAGG	RNF133	ENSG00000188050	0.19178825093423957	[261]	[376,493,313,288]	4	hSpCas9	negative selection	7329368
122698598	122698621	7	+	27260156	HT29	viability	CCGTTCAATAAGTGCAAGCCAGG	RNF133	ENSG00000188050	-0.009081483214691183	[428]	[636,464,572,411]	0	hSpCas9	negative selection	7329369
122698593	122698616	7	-	27260156	MHHES1	viability	CTTGCACTTATTGAACGGGGAGG	RNF133	ENSG00000188050	0.031963686645824274	[759]	[882,1025,800,802]	0	hSpCas9	negative selection	7386364
122698186	122698209	7	-	27260156	MHHES1	viability	CCAACTTCGAGTAGTAAAAGAGG	RNF133	ENSG00000188050	0.19894398401693736	[188]	[325,150,219,268]	3	hSpCas9	negative selection	7386365
122698146	122698169	7	+	27260156	MHHES1	viability	ATTACGCAGCTATCCCCATTTGG	RNF133	ENSG00000188050	0.5020969553217518	[800]	[1482,1448,1246,1007]	8	hSpCas9	negative selection	7386366
122698237	122698260	7	+	27260156	MHHES1	viability	TTGTTAATCGCTGCCATCTCCGG	RNF133	ENSG00000188050	0.34282629634164175	[1579]	[2141,2834,2590,1607]	6	hSpCas9	negative selection	7450618
122698384	122698407	7	-	27260156	MHHES1	viability	TCTCATTACAGCCGTGGTTGAGG	RNF133	ENSG00000188050	0.5078758500535043	[261]	[198,638,385,435]	8	hSpCas9	negative selection	7450619
122698598	122698621	7	+	27260156	MHHES1	viability	CCGTTCAATAAGTGCAAGCCAGG	RNF133	ENSG00000188050	0.157529142134647	[428]	[708,586,447,445]	3	hSpCas9	negative selection	7450620
122698593	122698616	7	-	27260156	MEWO	viability	CTTGCACTTATTGAACGGGGAGG	RNF133	ENSG00000188050	-0.019037506244284352	[759]	[844,644,642]	0	hSpCas9	negative selection	7507615
122698186	122698209	7	-	27260156	MEWO	viability	CCAACTTCGAGTAGTAAAAGAGG	RNF133	ENSG00000188050	-0.02029931810317276	[188]	[184,189,149]	0	hSpCas9	negative selection	7507616
122698146	122698169	7	+	27260156	MEWO	viability	ATTACGCAGCTATCCCCATTTGG	RNF133	ENSG00000188050	0.08575495045514314	[800]	[892,711,799]	2	hSpCas9	negative selection	7507617
122698237	122698260	7	+	27260156	MEWO	viability	TTGTTAATCGCTGCCATCTCCGG	RNF133	ENSG00000188050	0.153119328677354	[1579]	[2021,1444,1537]	3	hSpCas9	negative selection	7571869
122698384	122698407	7	-	27260156	MEWO	viability	TCTCATTACAGCCGTGGTTGAGG	RNF133	ENSG00000188050	0.182991735367932	[261]	[335,261,247]	4	hSpCas9	negative selection	7571870
122698598	122698621	7	+	27260156	MEWO	viability	CCGTTCAATAAGTGCAAGCCAGG	RNF133	ENSG00000188050	0.24329234791767512	[428]	[415,616,379]	5	hSpCas9	negative selection	7571871
122698593	122698616	7	-	27260156	LNCAPCLONEFGC	viability	CTTGCACTTATTGAACGGGGAGG	RNF133	ENSG00000188050	-0.3902924489534837	[759]	[338,607,606,556]	-6	hSpCas9	negative selection	7628866
122698186	122698209	7	-	27260156	LNCAPCLONEFGC	viability	CCAACTTCGAGTAGTAAAAGAGG	RNF133	ENSG00000188050	-0.10533943934420043	[188]	[233,84,172,149]	-2	hSpCas9	negative selection	7628867
122698146	122698169	7	+	27260156	LNCAPCLONEFGC	viability	ATTACGCAGCTATCCCCATTTGG	RNF133	ENSG00000188050	0.29339379795301457	[800]	[799,864,1194,744]	4	hSpCas9	negative selection	7628868
122698237	122698260	7	+	27260156	LNCAPCLONEFGC	viability	TTGTTAATCGCTGCCATCTCCGG	RNF133	ENSG00000188050	0.2200612379885445	[1579]	[1787,1361,2198,1414]	3	hSpCas9	negative selection	7693120
122698384	122698407	7	-	27260156	LNCAPCLONEFGC	viability	TCTCATTACAGCCGTGGTTGAGG	RNF133	ENSG00000188050	0.02966962271938589	[261]	[200,198,224,344]	0	hSpCas9	negative selection	7693121
122698598	122698621	7	+	27260156	LNCAPCLONEFGC	viability	CCGTTCAATAAGTGCAAGCCAGG	RNF133	ENSG00000188050	0.20778131190372268	[428]	[470,461,457,403]	3	hSpCas9	negative selection	7693122
122698593	122698616	7	-	27260156	PANC0327	viability	CTTGCACTTATTGAACGGGGAGG	RNF133	ENSG00000188050	-0.3117664575724841	[759]	[538,515,692,430]	-4	hSpCas9	negative selection	7750117
122698186	122698209	7	-	27260156	PANC0327	viability	CCAACTTCGAGTAGTAAAAGAGG	RNF133	ENSG00000188050	-0.1670770913959556	[188]	[153,69,295,88]	-2	hSpCas9	negative selection	7750118
122698146	122698169	7	+	27260156	PANC0327	viability	ATTACGCAGCTATCCCCATTTGG	RNF133	ENSG00000188050	0.03014321972139078	[800]	[1058,764,497,605]	0	hSpCas9	negative selection	7750119
122698237	122698260	7	+	27260156	PANC0327	viability	TTGTTAATCGCTGCCATCTCCGG	RNF133	ENSG00000188050	0.2766396084618885	[1579]	[1508,1560,1988,1743]	4	hSpCas9	negative selection	7814371
122698384	122698407	7	-	27260156	PANC0327	viability	TCTCATTACAGCCGTGGTTGAGG	RNF133	ENSG00000188050	0.5970581803578203	[261]	[390,166,335,540]	8	hSpCas9	negative selection	7814372
122698598	122698621	7	+	27260156	PANC0327	viability	CCGTTCAATAAGTGCAAGCCAGG	RNF133	ENSG00000188050	0.1300881100610242	[428]	[484,389,360,440]	2	hSpCas9	negative selection	7814373
122698593	122698616	7	-	27260156	NCIH2009	viability	CTTGCACTTATTGAACGGGGAGG	RNF133	ENSG00000188050	-0.3824351069625441	[759]	[1069,750,672]	-5	hSpCas9	negative selection	7871368
122698186	122698209	7	-	27260156	NCIH2009	viability	CCAACTTCGAGTAGTAAAAGAGG	RNF133	ENSG00000188050	-0.11367158984595749	[188]	[250,305,174]	-1	hSpCas9	negative selection	7871369
122698146	122698169	7	+	27260156	NCIH2009	viability	ATTACGCAGCTATCCCCATTTGG	RNF133	ENSG00000188050	0.3685467064975907	[800]	[1629,1316,1423]	5	hSpCas9	negative selection	7871370
122698237	122698260	7	+	27260156	NCIH2009	viability	TTGTTAATCGCTGCCATCTCCGG	RNF133	ENSG00000188050	0.08647192271956605	[1579]	[2961,1836,2359]	1	hSpCas9	negative selection	7935622
122698384	122698407	7	-	27260156	NCIH2009	viability	TCTCATTACAGCCGTGGTTGAGG	RNF133	ENSG00000188050	0.16445349805267406	[261]	[347,451,416]	2	hSpCas9	negative selection	7935623
122698598	122698621	7	+	27260156	NCIH2009	viability	CCGTTCAATAAGTGCAAGCCAGG	RNF133	ENSG00000188050	0.15388657446424453	[428]	[621,696,670]	2	hSpCas9	negative selection	7935624
122698593	122698616	7	-	27260156	NCIH1373	viability	CTTGCACTTATTGAACGGGGAGG	RNF133	ENSG00000188050	-0.4964016324542112	[759]	[1052,554,459,107]	-5	hSpCas9	negative selection	7992619
122698186	122698209	7	-	27260156	NCIH1373	viability	CCAACTTCGAGTAGTAAAAGAGG	RNF133	ENSG00000188050	-0.4078410919083275	[188]	[71,81,325,38]	-4	hSpCas9	negative selection	7992620
122698146	122698169	7	+	27260156	NCIH1373	viability	ATTACGCAGCTATCCCCATTTGG	RNF133	ENSG00000188050	0.5776469957952108	[800]	[1678,1169,1443,292]	6	hSpCas9	negative selection	7992621
122698237	122698260	7	+	27260156	NCIH1373	viability	TTGTTAATCGCTGCCATCTCCGG	RNF133	ENSG00000188050	0.10131713071863446	[1579]	[1989,1438,1815,641]	1	hSpCas9	negative selection	8056873
122698384	122698407	7	-	27260156	NCIH1373	viability	TCTCATTACAGCCGTGGTTGAGG	RNF133	ENSG00000188050	-0.38460216137130665	[261]	[239,185,239,62]	-4	hSpCas9	negative selection	8056874
122698598	122698621	7	+	27260156	NCIH1373	viability	CCGTTCAATAAGTGCAAGCCAGG	RNF133	ENSG00000188050	0.7703503502485767	[428]	[1053,670,978,159]	7	hSpCas9	negative selection	8056875
122698593	122698616	7	-	27260156	PATU8902	viability	CTTGCACTTATTGAACGGGGAGG	RNF133	ENSG00000188050	-0.3714407834221165	[759]	[682,1138,558,973]	-4	hSpCas9	negative selection	8113870
122698186	122698209	7	-	27260156	PATU8902	viability	CCAACTTCGAGTAGTAAAAGAGG	RNF133	ENSG00000188050	0.12838770337693228	[188]	[252,279,107,590]	1	hSpCas9	negative selection	8113871
122698146	122698169	7	+	27260156	PATU8902	viability	ATTACGCAGCTATCCCCATTTGG	RNF133	ENSG00000188050	0.7123592816761313	[800]	[1821,1758,1225,2756]	7	hSpCas9	negative selection	8113872
122698237	122698260	7	+	27260156	PATU8902	viability	TTGTTAATCGCTGCCATCTCCGG	RNF133	ENSG00000188050	0.7448726200827986	[1579]	[3517,3942,3880,3282]	7	hSpCas9	negative selection	8178124
122698384	122698407	7	-	27260156	PATU8902	viability	TCTCATTACAGCCGTGGTTGAGG	RNF133	ENSG00000188050	0.6959030289566901	[261]	[940,704,226,574]	7	hSpCas9	negative selection	8178125
122698598	122698621	7	+	27260156	PATU8902	viability	CCGTTCAATAAGTGCAAGCCAGG	RNF133	ENSG00000188050	0.5927913568065666	[428]	[609,604,1253,1057]	6	hSpCas9	negative selection	8178126
122698593	122698616	7	-	27260156	PANC1	viability	CTTGCACTTATTGAACGGGGAGG	RNF133	ENSG00000188050	-0.26597021392456094	[759]	[422,732,486,557]	-4	hSpCas9	negative selection	8235121
122698186	122698209	7	-	27260156	PANC1	viability	CCAACTTCGAGTAGTAAAAGAGG	RNF133	ENSG00000188050	0.27066045109739645	[188]	[94,293,226,187]	4	hSpCas9	negative selection	8235122
122698146	122698169	7	+	27260156	PANC1	viability	ATTACGCAGCTATCCCCATTTGG	RNF133	ENSG00000188050	0.41141547352384866	[800]	[1083,1045,756,798]	6	hSpCas9	negative selection	8235123
122698237	122698260	7	+	27260156	PANC1	viability	TTGTTAATCGCTGCCATCTCCGG	RNF133	ENSG00000188050	0.380763201203959	[1579]	[1658,2481,1478,1593]	6	hSpCas9	negative selection	8299375
122698384	122698407	7	-	27260156	PANC1	viability	TCTCATTACAGCCGTGGTTGAGG	RNF133	ENSG00000188050	-0.09071344851107999	[261]	[263,362,155,105]	-1	hSpCas9	negative selection	8299376
122698598	122698621	7	+	27260156	PANC1	viability	CCGTTCAATAAGTGCAAGCCAGG	RNF133	ENSG00000188050	0.6292005000966392	[428]	[546,715,699,371]	8	hSpCas9	negative selection	8299377
122698593	122698616	7	-	27260156	PANC0813	viability	CTTGCACTTATTGAACGGGGAGG	RNF133	ENSG00000188050	-0.24082742015480052	[759]	[749,654,641,960]	-4	hSpCas9	negative selection	8356372
122698186	122698209	7	-	27260156	PANC0813	viability	CCAACTTCGAGTAGTAAAAGAGG	RNF133	ENSG00000188050	0.4959247431479179	[188]	[307,314,257,366]	7	hSpCas9	negative selection	8356373
122698146	122698169	7	+	27260156	PANC0813	viability	ATTACGCAGCTATCCCCATTTGG	RNF133	ENSG00000188050	0.4867926040549895	[800]	[1372,1199,1244,1450]	7	hSpCas9	negative selection	8356374
122698237	122698260	7	+	27260156	PANC0813	viability	TTGTTAATCGCTGCCATCTCCGG	RNF133	ENSG00000188050	0.3255357711490048	[1579]	[2641,2039,2364,2283]	5	hSpCas9	negative selection	8420626
122698384	122698407	7	-	27260156	PANC0813	viability	TCTCATTACAGCCGTGGTTGAGG	RNF133	ENSG00000188050	0.35440171874779935	[261]	[425,350,452,348]	6	hSpCas9	negative selection	8420627
122698598	122698621	7	+	27260156	PANC0813	viability	CCGTTCAATAAGTGCAAGCCAGG	RNF133	ENSG00000188050	0.22290058369297433	[428]	[729,320,512,788]	3	hSpCas9	negative selection	8420628
122698593	122698616	7	-	27260156	RDES	viability	CTTGCACTTATTGAACGGGGAGG	RNF133	ENSG00000188050	-0.48059664305543737	[759]	[554,576,645,746]	-7	hSpCas9	negative selection	8477623
122698186	122698209	7	-	27260156	RDES	viability	CCAACTTCGAGTAGTAAAAGAGG	RNF133	ENSG00000188050	-0.058446357491909406	[188]	[145,183,221,308]	-1	hSpCas9	negative selection	8477624
122698146	122698169	7	+	27260156	RDES	viability	ATTACGCAGCTATCCCCATTTGG	RNF133	ENSG00000188050	0.4359840865239015	[800]	[970,1004,1456,1671]	7	hSpCas9	negative selection	8477625
122698237	122698260	7	+	27260156	RDES	viability	TTGTTAATCGCTGCCATCTCCGG	RNF133	ENSG00000188050	0.4533428713126997	[1579]	[1901,2419,2930,2826]	7	hSpCas9	negative selection	8541877
122698384	122698407	7	-	27260156	RDES	viability	TCTCATTACAGCCGTGGTTGAGG	RNF133	ENSG00000188050	0.05358432395855672	[261]	[177,296,473,333]	0	hSpCas9	negative selection	8541878
122698598	122698621	7	+	27260156	RDES	viability	CCGTTCAATAAGTGCAAGCCAGG	RNF133	ENSG00000188050	0.11608513397947322	[428]	[436,481,650,591]	2	hSpCas9	negative selection	8541879
122698593	122698616	7	-	27260156	PC3	viability	CTTGCACTTATTGAACGGGGAGG	RNF133	ENSG00000188050	-0.006090917264986451	[759]	[464,776,1326,722]	0	hSpCas9	negative selection	8598874
122698186	122698209	7	-	27260156	PC3	viability	CCAACTTCGAGTAGTAAAAGAGG	RNF133	ENSG00000188050	0.041471125829451116	[188]	[98,166,455,182]	0	hSpCas9	negative selection	8598875
122698146	122698169	7	+	27260156	PC3	viability	ATTACGCAGCTATCCCCATTTGG	RNF133	ENSG00000188050	-0.1604031514742923	[800]	[426,738,1088,809]	-4	hSpCas9	negative selection	8598876
122698237	122698260	7	+	27260156	PC3	viability	TTGTTAATCGCTGCCATCTCCGG	RNF133	ENSG00000188050	0.20772666861110567	[1579]	[1098,1960,2743,1971]	4	hSpCas9	negative selection	8663128
122698384	122698407	7	-	27260156	PC3	viability	TCTCATTACAGCCGTGGTTGAGG	RNF133	ENSG00000188050	0.2177186521405462	[261]	[168,183,693,362]	5	hSpCas9	negative selection	8663129
122698598	122698621	7	+	27260156	PC3	viability	CCGTTCAATAAGTGCAAGCCAGG	RNF133	ENSG00000188050	0.1271386462557412	[428]	[292,544,517,560]	3	hSpCas9	negative selection	8663130
122698593	122698616	7	-	27260156	PATU8988T	viability	CTTGCACTTATTGAACGGGGAGG	RNF133	ENSG00000188050	0.004523088951583598	[759]	[811,591,706,829]	0	hSpCas9	negative selection	8720125
122698186	122698209	7	-	27260156	PATU8988T	viability	CCAACTTCGAGTAGTAAAAGAGG	RNF133	ENSG00000188050	0.7785655202575595	[188]	[307,297,296,351]	9	hSpCas9	negative selection	8720126
122698146	122698169	7	+	27260156	PATU8988T	viability	ATTACGCAGCTATCCCCATTTGG	RNF133	ENSG00000188050	0.3915098308683349	[800]	[965,1118,798,1204]	6	hSpCas9	negative selection	8720127
122698237	122698260	7	+	27260156	PATU8988T	viability	TTGTTAATCGCTGCCATCTCCGG	RNF133	ENSG00000188050	0.2835973106199934	[1579]	[1604,1807,1619,2445]	5	hSpCas9	negative selection	8784379
122698384	122698407	7	-	27260156	PATU8988T	viability	TCTCATTACAGCCGTGGTTGAGG	RNF133	ENSG00000188050	-0.09619230725919958	[261]	[102,205,329,309]	-2	hSpCas9	negative selection	8784380
122698598	122698621	7	+	27260156	PATU8988T	viability	CCGTTCAATAAGTGCAAGCCAGG	RNF133	ENSG00000188050	0.2263332282252961	[428]	[472,408,510,543]	4	hSpCas9	negative selection	8784381
122698593	122698616	7	-	27260156	T47D	viability	CTTGCACTTATTGAACGGGGAGG	RNF133	ENSG00000188050	-0.05371401109069962	[759]	[739,872,925,869]	-1	hSpCas9	negative selection	8841376
122698186	122698209	7	-	27260156	T47D	viability	CCAACTTCGAGTAGTAAAAGAGG	RNF133	ENSG00000188050	0.07618425487510683	[188]	[251,190,229,259]	1	hSpCas9	negative selection	8841377
122698146	122698169	7	+	27260156	T47D	viability	ATTACGCAGCTATCCCCATTTGG	RNF133	ENSG00000188050	0.3281007837454748	[800]	[1271,1029,1168,1228]	7	hSpCas9	negative selection	8841378
122698237	122698260	7	+	27260156	T47D	viability	TTGTTAATCGCTGCCATCTCCGG	RNF133	ENSG00000188050	0.3058041104489788	[1579]	[2333,2162,2161,2458]	6	hSpCas9	negative selection	8905630
122698384	122698407	7	-	27260156	T47D	viability	TCTCATTACAGCCGTGGTTGAGG	RNF133	ENSG00000188050	0.1822344841391209	[261]	[378,318,337,351]	4	hSpCas9	negative selection	8905631
122698598	122698621	7	+	27260156	T47D	viability	CCGTTCAATAAGTGCAAGCCAGG	RNF133	ENSG00000188050	0.1799492801300484	[428]	[558,615,475,611]	4	hSpCas9	negative selection	8905632
122698593	122698616	7	-	27260156	SU8686	viability	CTTGCACTTATTGAACGGGGAGG	RNF133	ENSG00000188050	0.12731206613177393	[759]	[771,629,1071,854]	2	hSpCas9	negative selection	8962627
122698186	122698209	7	-	27260156	SU8686	viability	CCAACTTCGAGTAGTAAAAGAGG	RNF133	ENSG00000188050	0.44634490410208916	[188]	[149,213,306,388]	7	hSpCas9	negative selection	8962628
122698146	122698169	7	+	27260156	SU8686	viability	ATTACGCAGCTATCCCCATTTGG	RNF133	ENSG00000188050	0.35889463605733485	[800]	[910,878,1073,1275]	6	hSpCas9	negative selection	8962629
122698237	122698260	7	+	27260156	SU8686	viability	TTGTTAATCGCTGCCATCTCCGG	RNF133	ENSG00000188050	0.2842442700000676	[1579]	[1650,1710,2186,2172]	5	hSpCas9	negative selection	9026881
122698384	122698407	7	-	27260156	SU8686	viability	TCTCATTACAGCCGTGGTTGAGG	RNF133	ENSG00000188050	0.08359011833159435	[261]	[231,280,298,294]	1	hSpCas9	negative selection	9026882
122698598	122698621	7	+	27260156	SU8686	viability	CCGTTCAATAAGTGCAAGCCAGG	RNF133	ENSG00000188050	-0.08737588157588297	[428]	[402,366,334,513]	-1	hSpCas9	negative selection	9026883
122698593	122698616	7	-	27260156	SKES1	viability	CTTGCACTTATTGAACGGGGAGG	RNF133	ENSG00000188050	-0.213174090511709	[759]	[825,657,700,469]	-5	hSpCas9	negative selection	9083878
122698186	122698209	7	-	27260156	SKES1	viability	CCAACTTCGAGTAGTAAAAGAGG	RNF133	ENSG00000188050	-0.2653947696212582	[188]	[152,166,164,142]	-5	hSpCas9	negative selection	9083879
122698146	122698169	7	+	27260156	SKES1	viability	ATTACGCAGCTATCCCCATTTGG	RNF133	ENSG00000188050	0.19670071340021167	[800]	[1108,968,722,890]	4	hSpCas9	negative selection	9083880
122698237	122698260	7	+	27260156	SKES1	viability	TTGTTAATCGCTGCCATCTCCGG	RNF133	ENSG00000188050	0.138797061820638	[1579]	[1992,1921,1822,1294]	3	hSpCas9	negative selection	9148132
122698384	122698407	7	-	27260156	SKES1	viability	TCTCATTACAGCCGTGGTTGAGG	RNF133	ENSG00000188050	0.25538443566432656	[261]	[347,309,292,299]	5	hSpCas9	negative selection	9148133
122698598	122698621	7	+	27260156	SKES1	viability	CCGTTCAATAAGTGCAAGCCAGG	RNF133	ENSG00000188050	0.14570312837258062	[428]	[530,510,414,447]	3	hSpCas9	negative selection	9148134
122698593	122698616	7	-	27260156	TOV112D	viability	CTTGCACTTATTGAACGGGGAGG	RNF133	ENSG00000188050	-0.2700862493598453	[759]	[609,986,612,405]	-5	hSpCas9	negative selection	9205129
122698186	122698209	7	-	27260156	TOV112D	viability	CCAACTTCGAGTAGTAAAAGAGG	RNF133	ENSG00000188050	0.056404295716949715	[188]	[102,211,275,191]	1	hSpCas9	negative selection	9205130
122698146	122698169	7	+	27260156	TOV112D	viability	ATTACGCAGCTATCCCCATTTGG	RNF133	ENSG00000188050	0.1324058833313697	[800]	[973,1166,620,833]	2	hSpCas9	negative selection	9205131
122698237	122698260	7	+	27260156	TOV112D	viability	TTGTTAATCGCTGCCATCTCCGG	RNF133	ENSG00000188050	0.3133794471284792	[1579]	[2005,2253,2131,1555]	6	hSpCas9	negative selection	9269383
122698384	122698407	7	-	27260156	TOV112D	viability	TCTCATTACAGCCGTGGTTGAGG	RNF133	ENSG00000188050	0.049700865838393504	[261]	[340,321,161,278]	1	hSpCas9	negative selection	9269384
122698598	122698621	7	+	27260156	TOV112D	viability	CCGTTCAATAAGTGCAAGCCAGG	RNF133	ENSG00000188050	0.059610250508532664	[428]	[501,410,608,268]	1	hSpCas9	negative selection	9269385
122698593	122698616	7	-	27260156	TC71	viability	CTTGCACTTATTGAACGGGGAGG	RNF133	ENSG00000188050	0.043347901999878036	[759]	[783,877,853,842]	1	hSpCas9	negative selection	9326380
122698186	122698209	7	-	27260156	TC71	viability	CCAACTTCGAGTAGTAAAAGAGG	RNF133	ENSG00000188050	0.14225079604647783	[188]	[185,251,221,235]	3	hSpCas9	negative selection	9326381
122698146	122698169	7	+	27260156	TC71	viability	ATTACGCAGCTATCCCCATTTGG	RNF133	ENSG00000188050	0.2394983519901872	[800]	[833,1320,819,1094]	6	hSpCas9	negative selection	9326382
122698237	122698260	7	+	27260156	TC71	viability	TTGTTAATCGCTGCCATCTCCGG	RNF133	ENSG00000188050	0.21168036950373748	[1579]	[1751,2085,1778,2256]	5	hSpCas9	negative selection	9390634
122698384	122698407	7	-	27260156	TC71	viability	TCTCATTACAGCCGTGGTTGAGG	RNF133	ENSG00000188050	0.35958047739176063	[261]	[384,308,255,502]	8	hSpCas9	negative selection	9390635
122698598	122698621	7	+	27260156	TC71	viability	CCGTTCAATAAGTGCAAGCCAGG	RNF133	ENSG00000188050	0.060949446923678666	[428]	[329,565,603,413]	1	hSpCas9	negative selection	9390636
122698593	122698616	7	-	27260156	TC32	viability	CTTGCACTTATTGAACGGGGAGG	RNF133	ENSG00000188050	-0.4295178753396003	[759]	[550,345,697,594]	-7	hSpCas9	negative selection	9447631
122698186	122698209	7	-	27260156	TC32	viability	CCAACTTCGAGTAGTAAAAGAGG	RNF133	ENSG00000188050	-0.06607352689031432	[188]	[136,168,227,146]	-1	hSpCas9	negative selection	9447632
122698146	122698169	7	+	27260156	TC32	viability	ATTACGCAGCTATCCCCATTTGG	RNF133	ENSG00000188050	-0.02845208350384487	[800]	[770,463,966,852]	0	hSpCas9	negative selection	9447633
122698237	122698260	7	+	27260156	TC32	viability	TTGTTAATCGCTGCCATCTCCGG	RNF133	ENSG00000188050	-0.0033201318488980114	[1579]	[1370,1026,1874,1840]	0	hSpCas9	negative selection	9511885
122698384	122698407	7	-	27260156	TC32	viability	TCTCATTACAGCCGTGGTTGAGG	RNF133	ENSG00000188050	-0.045363254581862744	[261]	[148,210,337,283]	-1	hSpCas9	negative selection	9511886
122698598	122698621	7	+	27260156	TC32	viability	CCGTTCAATAAGTGCAAGCCAGG	RNF133	ENSG00000188050	0.08522022333896069	[428]	[422,303,510,513]	1	hSpCas9	negative selection	9511887
122697847	122697870	7	+	27869803	HPAFII	viability after 27 days	AAGTAGGGTTCTCCTCCACATGG	RNF133	ENSG00000188050	1.3218897248281603	[93]	[254,13,NaN]	9	hSpCas9	negative selection	9597785
122698381	122698404	7	-	27869803	HPAFII	viability after 27 days	CATTACAGCCGTGGTTGAGGTGG	RNF133	ENSG00000188050	1.1707953536075124	[200]	[436,71,NaN]	8	hSpCas9	negative selection	9597786
122698390	122698413	7	-	27869803	HPAFII	viability after 27 days	GGGAGTTCTCATTACAGCCGTGG	RNF133	ENSG00000188050	0.36546317176384235	[130]	[13,150,NaN]	3	hSpCas9	negative selection	9597787
122698596	122698619	7	-	27869803	HPAFII	viability after 27 days	TGGCTTGCACTTATTGAACGGGG	RNF133	ENSG00000188050	0.4721039557542954	[682]	[508,488,NaN]	4	hSpCas9	negative selection	9597788
122698597	122698620	7	-	27869803	HPAFII	viability after 27 days	CTGGCTTGCACTTATTGAACGGG	RNF133	ENSG00000188050	1.411884618591438	[767]	[1327,862,NaN]	9	hSpCas9	negative selection	9597789
122698616	122698639	7	-	27869803	HPAFII	viability after 27 days	GATCAAAGTACTCAGAGACCTGG	RNF133	ENSG00000188050	-0.8399734596239257	[103]	[65,0,NaN]	-5	hSpCas9	negative selection	9597790
122697847	122697870	7	+	27869803	HPAFII	viability after 15 days	AAGTAGGGTTCTCCTCCACATGG	RNF133	ENSG00000188050	1.248932704354258	[93]	[421,126,NaN]	9	hSpCas9	negative selection	9680234
122698381	122698404	7	-	27869803	HPAFII	viability after 15 days	CATTACAGCCGTGGTTGAGGTGG	RNF133	ENSG00000188050	0.335395089616531	[200]	[533,109,NaN]	4	hSpCas9	negative selection	9680235
122698390	122698413	7	-	27869803	HPAFII	viability after 15 days	GGGAGTTCTCATTACAGCCGTGG	RNF133	ENSG00000188050	0.33156129977909343	[130]	[170,180,NaN]	4	hSpCas9	negative selection	9680236
122698596	122698619	7	-	27869803	HPAFII	viability after 15 days	TGGCTTGCACTTATTGAACGGGG	RNF133	ENSG00000188050	0.13941628515225202	[682]	[974,704,NaN]	1	hSpCas9	negative selection	9680237
122698597	122698620	7	-	27869803	HPAFII	viability after 15 days	CTGGCTTGCACTTATTGAACGGG	RNF133	ENSG00000188050	0.9294325031173052	[767]	[2084,1252,NaN]	8	hSpCas9	negative selection	9680238
122698616	122698639	7	-	27869803	HPAFII	viability after 15 days	GATCAAAGTACTCAGAGACCTGG	RNF133	ENSG00000188050	-0.7090262988080076	[103]	[150,16,NaN]	-6	hSpCas9	negative selection	9680239
122697847	122697870	7	+	27869803	ASPC1	viability after 36 days	AAGTAGGGTTCTCCTCCACATGG	RNF133	ENSG00000188050	-0.4486641648330666	[460]	[158,186,32]	-4	hSpCas9	negative selection	9762683
122698381	122698404	7	-	27869803	ASPC1	viability after 36 days	CATTACAGCCGTGGTTGAGGTGG	RNF133	ENSG00000188050	-0.4416299640589757	[714]	[188,217,150]	-4	hSpCas9	negative selection	9762684
122698390	122698413	7	-	27869803	ASPC1	viability after 36 days	GGGAGTTCTCATTACAGCCGTGG	RNF133	ENSG00000188050	0.8378250720432039	[337]	[281,294,91]	7	hSpCas9	negative selection	9762685
122698596	122698619	7	-	27869803	ASPC1	viability after 36 days	TGGCTTGCACTTATTGAACGGGG	RNF133	ENSG00000188050	0.6064868684184364	[1595]	[642,1155,738]	6	hSpCas9	negative selection	9762686
122698597	122698620	7	-	27869803	ASPC1	viability after 36 days	CTGGCTTGCACTTATTGAACGGG	RNF133	ENSG00000188050	0.7891638120098485	[1730]	[1675,897,705]	7	hSpCas9	negative selection	9762687
122698616	122698639	7	-	27869803	ASPC1	viability after 36 days	GATCAAAGTACTCAGAGACCTGG	RNF133	ENSG00000188050	-1.0579489676695453	[225]	[39,81,0]	-7	hSpCas9	negative selection	9762688
122697847	122697870	7	+	27869803	PATU8988S	viability after 35 days	AAGTAGGGTTCTCCTCCACATGG	RNF133	ENSG00000188050	0.11015039452061792	[327]	[178,105,NaN]	1	hSpCas9	negative selection	9845132
122698381	122698404	7	-	27869803	PATU8988S	viability after 35 days	CATTACAGCCGTGGTTGAGGTGG	RNF133	ENSG00000188050	-0.4232366656490703	[410]	[98,147,NaN]	-4	hSpCas9	negative selection	9845133
122698390	122698413	7	-	27869803	PATU8988S	viability after 35 days	GGGAGTTCTCATTACAGCCGTGG	RNF133	ENSG00000188050	0.4738183684159108	[332]	[298,72,NaN]	5	hSpCas9	negative selection	9845134
122698596	122698619	7	-	27869803	PATU8988S	viability after 35 days	TGGCTTGCACTTATTGAACGGGG	RNF133	ENSG00000188050	0.03338299728385663	[1450]	[628,566,NaN]	0	hSpCas9	negative selection	9845135
122698597	122698620	7	-	27869803	PATU8988S	viability after 35 days	CTGGCTTGCACTTATTGAACGGG	RNF133	ENSG00000188050	0.7815117306178221	[1542]	[1163,971,NaN]	8	hSpCas9	negative selection	9845136
122698616	122698639	7	-	27869803	PATU8988S	viability after 35 days	GATCAAAGTACTCAGAGACCTGG	RNF133	ENSG00000188050	0.3229772869051962	[252]	[110,143,NaN]	3	hSpCas9	negative selection	9845137
122697847	122697870	7	+	27869803	PATU8988S	viability after 31 days	AAGTAGGGTTCTCCTCCACATGG	RNF133	ENSG00000188050	-0.029654277561639075	[327]	[161,84,NaN]	0	hSpCas9	negative selection	9927581
122698381	122698404	7	-	27869803	PATU8988S	viability after 31 days	CATTACAGCCGTGGTTGAGGTGG	RNF133	ENSG00000188050	0.094552856972696	[410]	[97,272,NaN]	1	hSpCas9	negative selection	9927582
122698390	122698413	7	-	27869803	PATU8988S	viability after 31 days	GGGAGTTCTCATTACAGCCGTGG	RNF133	ENSG00000188050	0.6367461479695414	[332]	[260,136,NaN]	7	hSpCas9	negative selection	9927583
122698596	122698619	7	-	27869803	PATU8988S	viability after 31 days	TGGCTTGCACTTATTGAACGGGG	RNF133	ENSG00000188050	0.2823140118104044	[1450]	[667,748,NaN]	3	hSpCas9	negative selection	9927584
122698597	122698620	7	-	27869803	PATU8988S	viability after 31 days	CTGGCTTGCACTTATTGAACGGG	RNF133	ENSG00000188050	0.6327354333034838	[1542]	[971,930,NaN]	7	hSpCas9	negative selection	9927585
122698616	122698639	7	-	27869803	PATU8988S	viability after 31 days	GATCAAAGTACTCAGAGACCTGG	RNF133	ENSG00000188050	0.153309177005012	[252]	[76,156,NaN]	2	hSpCas9	negative selection	9927586
122697847	122697870	7	+	27869803	HPAFII	viability after 35 days	AAGTAGGGTTCTCCTCCACATGG	RNF133	ENSG00000188050	1.6902816371907887	[93]	[241,53,NaN]	9	hSpCas9	negative selection	10010030
122698381	122698404	7	-	27869803	HPAFII	viability after 35 days	CATTACAGCCGTGGTTGAGGTGG	RNF133	ENSG00000188050	1.4870549668141766	[200]	[407,146,NaN]	8	hSpCas9	negative selection	10010031
122698390	122698413	7	-	27869803	HPAFII	viability after 35 days	GGGAGTTCTCATTACAGCCGTGG	RNF133	ENSG00000188050	0.9268050972747156	[130]	[39,222,NaN]	6	hSpCas9	negative selection	10010032
122698596	122698619	7	-	27869803	HPAFII	viability after 35 days	TGGCTTGCACTTATTGAACGGGG	RNF133	ENSG00000188050	0.5922960507077184	[682]	[398,658,NaN]	4	hSpCas9	negative selection	10010033
122698597	122698620	7	-	27869803	HPAFII	viability after 35 days	CTGGCTTGCACTTATTGAACGGG	RNF133	ENSG00000188050	1.5378396499968898	[767]	[1063,1201,NaN]	8	hSpCas9	negative selection	10010034
122698616	122698639	7	-	27869803	HPAFII	viability after 35 days	GATCAAAGTACTCAGAGACCTGG	RNF133	ENSG00000188050	-0.883361812643074	[103]	[52,0,NaN]	-5	hSpCas9	negative selection	10010035
122697847	122697870	7	+	27869803	HPAFII	viability after 31 days	AAGTAGGGTTCTCCTCCACATGG	RNF133	ENSG00000188050	1.35994238224489	[93]	[244,15,NaN]	8	hSpCas9	negative selection	10092479
122698381	122698404	7	-	27869803	HPAFII	viability after 31 days	CATTACAGCCGTGGTTGAGGTGG	RNF133	ENSG00000188050	0.9994859133357489	[200]	[348,90,NaN]	7	hSpCas9	negative selection	10092480
122698390	122698413	7	-	27869803	HPAFII	viability after 31 days	GGGAGTTCTCATTACAGCCGTGG	RNF133	ENSG00000188050	0.3123782795467882	[130]	[41,144,NaN]	2	hSpCas9	negative selection	10092481
122698596	122698619	7	-	27869803	HPAFII	viability after 31 days	TGGCTTGCACTTATTGAACGGGG	RNF133	ENSG00000188050	0.7195338477113442	[682]	[623,638,NaN]	5	hSpCas9	negative selection	10092482
122698597	122698620	7	-	27869803	HPAFII	viability after 31 days	CTGGCTTGCACTTATTGAACGGG	RNF133	ENSG00000188050	1.3760069749789172	[767]	[1189,1040,NaN]	8	hSpCas9	negative selection	10092483
122698616	122698639	7	-	27869803	HPAFII	viability after 31 days	GATCAAAGTACTCAGAGACCTGG	RNF133	ENSG00000188050	-0.28425448432325484	[103]	[90,0,NaN]	-2	hSpCas9	negative selection	10092484
122698680	122698703	7	-	28162770	P31FUJ	viability	GGAGTTATAGTGCCACCAGAGGG	RNF133	ENSG00000188050	0.51685048820539	[316]	[532]	6	hSpCas9	negative selection	10226101
122697777	122697800	7	+	28162770	P31FUJ	viability	AAGTCATGCCATCAAGGTGAAGG	RNF133	ENSG00000188050	0.7193031054813099	[244]	[473]	8	hSpCas9	negative selection	10226102
122698542	122698565	7	-	28162770	P31FUJ	viability	GCAACTGAGAAGGGAGCCAGTGG	RNF133	ENSG00000188050	-0.09132977846149815	[164]	[181]	-1	hSpCas9	negative selection	10226103
122698390	122698413	7	-	28162770	P31FUJ	viability	GGGAGTTCTCATTACAGCCGTGG	RNF133	ENSG00000188050	0.2615577475258707	[114]	[161]	3	hSpCas9	negative selection	10226104
122698856	122698879	7	+	28162770	P31FUJ	viability	GAACTTCATAAGCCAGGAAGAGG	RNF133	ENSG00000188050	0.35640976930813545	[225]	[339]	4	hSpCas9	negative selection	10226105
122698047	122698070	7	-	28162770	P31FUJ	viability	GACCCCTGGATTTTACCCCATGG	RNF133	ENSG00000188050	0.1385139174351472	[200]	[259]	1	hSpCas9	negative selection	10226106
122698903	122698926	7	-	28162770	P31FUJ	viability	GAGAGAGATGCATCTACTCAAGG	RNF133	ENSG00000188050	-0.05647943177391568	[399]	[451]	0	hSpCas9	negative selection	10226107
122698593	122698616	7	-	28162770	P31FUJ	viability	CTTGCACTTATTGAACGGGGAGG	RNF133	ENSG00000188050	0.26469745505643805	[339]	[479]	3	hSpCas9	negative selection	10226108
122698373	122698396	7	+	28162770	P31FUJ	viability	CTTTCTCCCCACCTCAACCACGG	RNF133	ENSG00000188050	-0.6047709818013365	[1055]	[815]	-5	hSpCas9	negative selection	10226109
122698250	122698273	7	-	28162770	P31FUJ	viability	CAAGGATTCAGAACCGGAGATGG	RNF133	ENSG00000188050	0.29428691980720645	[745]	[1074]	3	hSpCas9	negative selection	10226110
122698680	122698703	7	-	28162770	TF1	viability	GGAGTTATAGTGCCACCAGAGGG	RNF133	ENSG00000188050	NaN	[NaN]	[419]	1	hSpCas9	negative selection	10395467
122697777	122697800	7	+	28162770	TF1	viability	AAGTCATGCCATCAAGGTGAAGG	RNF133	ENSG00000188050	NaN	[NaN]	[242]	1	hSpCas9	negative selection	10395468
122698542	122698565	7	-	28162770	TF1	viability	GCAACTGAGAAGGGAGCCAGTGG	RNF133	ENSG00000188050	NaN	[NaN]	[138]	1	hSpCas9	negative selection	10395469
122698390	122698413	7	-	28162770	TF1	viability	GGGAGTTCTCATTACAGCCGTGG	RNF133	ENSG00000188050	NaN	[NaN]	[98]	1	hSpCas9	negative selection	10395470
122698856	122698879	7	+	28162770	TF1	viability	GAACTTCATAAGCCAGGAAGAGG	RNF133	ENSG00000188050	NaN	[NaN]	[316]	1	hSpCas9	negative selection	10395471
122698047	122698070	7	-	28162770	TF1	viability	GACCCCTGGATTTTACCCCATGG	RNF133	ENSG00000188050	NaN	[NaN]	[244]	1	hSpCas9	negative selection	10395472
122698903	122698926	7	-	28162770	TF1	viability	GAGAGAGATGCATCTACTCAAGG	RNF133	ENSG00000188050	NaN	[NaN]	[384]	1	hSpCas9	negative selection	10395473
122698593	122698616	7	-	28162770	TF1	viability	CTTGCACTTATTGAACGGGGAGG	RNF133	ENSG00000188050	NaN	[NaN]	[229]	1	hSpCas9	negative selection	10395474
122698373	122698396	7	+	28162770	TF1	viability	CTTTCTCCCCACCTCAACCACGG	RNF133	ENSG00000188050	NaN	[NaN]	[587]	1	hSpCas9	negative selection	10395475
122698250	122698273	7	-	28162770	TF1	viability	CAAGGATTCAGAACCGGAGATGG	RNF133	ENSG00000188050	NaN	[NaN]	[369]	1	hSpCas9	negative selection	10395476
122698680	122698703	7	-	28162770	SKM1	viability	GGAGTTATAGTGCCACCAGAGGG	RNF133	ENSG00000188050	0.2033093905071819	[112]	[229]	2	hSpCas9	negative selection	10564833
122697777	122697800	7	+	28162770	SKM1	viability	AAGTCATGCCATCAAGGTGAAGG	RNF133	ENSG00000188050	0.0817829867186913	[61]	[115]	0	hSpCas9	negative selection	10564834
122698542	122698565	7	-	28162770	SKM1	viability	GCAACTGAGAAGGGAGCCAGTGG	RNF133	ENSG00000188050	0.32044256699819995	[52]	[116]	3	hSpCas9	negative selection	10564835
122698390	122698413	7	-	28162770	SKM1	viability	GGGAGTTCTCATTACAGCCGTGG	RNF133	ENSG00000188050	-0.1384753628172597	[32]	[52]	-1	hSpCas9	negative selection	10564836
122698856	122698879	7	+	28162770	SKM1	viability	GAACTTCATAAGCCAGGAAGAGG	RNF133	ENSG00000188050	0.1779983019779945	[78]	[157]	1	hSpCas9	negative selection	10564837
122698047	122698070	7	-	28162770	SKM1	viability	GACCCCTGGATTTTACCCCATGG	RNF133	ENSG00000188050	-0.4069641987431615	[74]	[99]	-3	hSpCas9	negative selection	10564838
122698903	122698926	7	-	28162770	SKM1	viability	GAGAGAGATGCATCTACTCAAGG	RNF133	ENSG00000188050	0.057704068260282626	[99]	[183]	0	hSpCas9	negative selection	10564839
122698593	122698616	7	-	28162770	SKM1	viability	CTTGCACTTATTGAACGGGGAGG	RNF133	ENSG00000188050	-0.05229931744379937	[60]	[103]	0	hSpCas9	negative selection	10564840
122698373	122698396	7	+	28162770	SKM1	viability	CTTTCTCCCCACCTCAACCACGG	RNF133	ENSG00000188050	0.11401767607617264	[218]	[418]	1	hSpCas9	negative selection	10564841
122698250	122698273	7	-	28162770	SKM1	viability	CAAGGATTCAGAACCGGAGATGG	RNF133	ENSG00000188050	0.20036611500644907	[159]	[324]	2	hSpCas9	negative selection	10564842
122698680	122698703	7	-	28162770	SKM1	viability	GGAGTTATAGTGCCACCAGAGGG	RNF133	ENSG00000188050	0.2033093905071819	[112]	[229]	2	hSpCas9	negative selection	10734199
122697777	122697800	7	+	28162770	SKM1	viability	AAGTCATGCCATCAAGGTGAAGG	RNF133	ENSG00000188050	0.0817829867186913	[61]	[115]	0	hSpCas9	negative selection	10734200
122698542	122698565	7	-	28162770	SKM1	viability	GCAACTGAGAAGGGAGCCAGTGG	RNF133	ENSG00000188050	0.32044256699819995	[52]	[116]	3	hSpCas9	negative selection	10734201
122698390	122698413	7	-	28162770	SKM1	viability	GGGAGTTCTCATTACAGCCGTGG	RNF133	ENSG00000188050	-0.1384753628172597	[32]	[52]	-1	hSpCas9	negative selection	10734202
122698856	122698879	7	+	28162770	SKM1	viability	GAACTTCATAAGCCAGGAAGAGG	RNF133	ENSG00000188050	0.1779983019779945	[78]	[157]	1	hSpCas9	negative selection	10734203
122698047	122698070	7	-	28162770	SKM1	viability	GACCCCTGGATTTTACCCCATGG	RNF133	ENSG00000188050	-0.4069641987431615	[74]	[99]	-3	hSpCas9	negative selection	10734204
122698903	122698926	7	-	28162770	SKM1	viability	GAGAGAGATGCATCTACTCAAGG	RNF133	ENSG00000188050	0.057704068260282626	[99]	[183]	0	hSpCas9	negative selection	10734205
122698593	122698616	7	-	28162770	SKM1	viability	CTTGCACTTATTGAACGGGGAGG	RNF133	ENSG00000188050	-0.05229931744379937	[60]	[103]	0	hSpCas9	negative selection	10734206
122698373	122698396	7	+	28162770	SKM1	viability	CTTTCTCCCCACCTCAACCACGG	RNF133	ENSG00000188050	0.11401767607617264	[218]	[418]	1	hSpCas9	negative selection	10734207
122698250	122698273	7	-	28162770	SKM1	viability	CAAGGATTCAGAACCGGAGATGG	RNF133	ENSG00000188050	0.20036611500644907	[159]	[324]	2	hSpCas9	negative selection	10734208
122698680	122698703	7	-	28162770	PL21	viability	GGAGTTATAGTGCCACCAGAGGG	RNF133	ENSG00000188050	0.2658157887576892	[364]	[190]	2	hSpCas9	negative selection	10903565
122697777	122697800	7	+	28162770	PL21	viability	AAGTCATGCCATCAAGGTGAAGG	RNF133	ENSG00000188050	0.3585052101579095	[180]	[100]	3	hSpCas9	negative selection	10903566
122698542	122698565	7	-	28162770	PL21	viability	GCAACTGAGAAGGGAGCCAGTGG	RNF133	ENSG00000188050	0.16186959756160296	[190]	[92]	1	hSpCas9	negative selection	10903567
122698390	122698413	7	-	28162770	PL21	viability	GGGAGTTCTCATTACAGCCGTGG	RNF133	ENSG00000188050	0.6497155324726429	[226]	[154]	5	hSpCas9	negative selection	10903568
122698856	122698879	7	+	28162770	PL21	viability	GAACTTCATAAGCCAGGAAGAGG	RNF133	ENSG00000188050	0.7235097355562372	[326]	[234]	6	hSpCas9	negative selection	10903569
122698047	122698070	7	-	28162770	PL21	viability	GACCCCTGGATTTTACCCCATGG	RNF133	ENSG00000188050	0.8923557019222276	[202]	[163]	7	hSpCas9	negative selection	10903570
122698903	122698926	7	-	28162770	PL21	viability	GAGAGAGATGCATCTACTCAAGG	RNF133	ENSG00000188050	-0.2060740344025176	[325]	[122]	-1	hSpCas9	negative selection	10903571
122698593	122698616	7	-	28162770	PL21	viability	CTTGCACTTATTGAACGGGGAGG	RNF133	ENSG00000188050	-0.17219343383528551	[232]	[89]	-1	hSpCas9	negative selection	10903572
122698373	122698396	7	+	28162770	PL21	viability	CTTTCTCCCCACCTCAACCACGG	RNF133	ENSG00000188050	-0.3200145906037377	[739]	[257]	-2	hSpCas9	negative selection	10903573
122698250	122698273	7	-	28162770	PL21	viability	CAAGGATTCAGAACCGGAGATGG	RNF133	ENSG00000188050	0.1761939188642876	[485]	[238]	1	hSpCas9	negative selection	10903574
122698680	122698703	7	-	28162770	P31FUJ	viability	GGAGTTATAGTGCCACCAGAGGG	RNF133	ENSG00000188050	0.51685048820539	[316]	[532]	6	hSpCas9	negative selection	11072931
122697777	122697800	7	+	28162770	P31FUJ	viability	AAGTCATGCCATCAAGGTGAAGG	RNF133	ENSG00000188050	0.7193031054813099	[244]	[473]	8	hSpCas9	negative selection	11072932
122698542	122698565	7	-	28162770	P31FUJ	viability	GCAACTGAGAAGGGAGCCAGTGG	RNF133	ENSG00000188050	-0.09132977846149815	[164]	[181]	-1	hSpCas9	negative selection	11072933
122698390	122698413	7	-	28162770	P31FUJ	viability	GGGAGTTCTCATTACAGCCGTGG	RNF133	ENSG00000188050	0.2615577475258707	[114]	[161]	3	hSpCas9	negative selection	11072934
122698856	122698879	7	+	28162770	P31FUJ	viability	GAACTTCATAAGCCAGGAAGAGG	RNF133	ENSG00000188050	0.35640976930813545	[225]	[339]	4	hSpCas9	negative selection	11072935
122698047	122698070	7	-	28162770	P31FUJ	viability	GACCCCTGGATTTTACCCCATGG	RNF133	ENSG00000188050	0.1385139174351472	[200]	[259]	1	hSpCas9	negative selection	11072936
122698903	122698926	7	-	28162770	P31FUJ	viability	GAGAGAGATGCATCTACTCAAGG	RNF133	ENSG00000188050	-0.05647943177391568	[399]	[451]	0	hSpCas9	negative selection	11072937
122698593	122698616	7	-	28162770	P31FUJ	viability	CTTGCACTTATTGAACGGGGAGG	RNF133	ENSG00000188050	0.26469745505643805	[339]	[479]	3	hSpCas9	negative selection	11072938
122698373	122698396	7	+	28162770	P31FUJ	viability	CTTTCTCCCCACCTCAACCACGG	RNF133	ENSG00000188050	-0.6047709818013365	[1055]	[815]	-5	hSpCas9	negative selection	11072939
122698250	122698273	7	-	28162770	P31FUJ	viability	CAAGGATTCAGAACCGGAGATGG	RNF133	ENSG00000188050	0.29428691980720645	[745]	[1074]	3	hSpCas9	negative selection	11072940
122698680	122698703	7	-	28162770	OCIAML5	viability	GGAGTTATAGTGCCACCAGAGGG	RNF133	ENSG00000188050	0.5849972347448457	[194]	[527]	5	hSpCas9	negative selection	11242297
122697777	122697800	7	+	28162770	OCIAML5	viability	AAGTCATGCCATCAAGGTGAAGG	RNF133	ENSG00000188050	1.016869673383316	[94]	[346]	8	hSpCas9	negative selection	11242298
122698542	122698565	7	-	28162770	OCIAML5	viability	GCAACTGAGAAGGGAGCCAGTGG	RNF133	ENSG00000188050	1.3627126663625757	[94]	[440]	9	hSpCas9	negative selection	11242299
122698390	122698413	7	-	28162770	OCIAML5	viability	GGGAGTTCTCATTACAGCCGTGG	RNF133	ENSG00000188050	-0.23165523413855127	[66]	[102]	-2	hSpCas9	negative selection	11242300
122698856	122698879	7	+	28162770	OCIAML5	viability	GAACTTCATAAGCCAGGAAGAGG	RNF133	ENSG00000188050	1.2737773621141983	[95]	[418]	9	hSpCas9	negative selection	11242301
122698047	122698070	7	-	28162770	OCIAML5	viability	GACCCCTGGATTTTACCCCATGG	RNF133	ENSG00000188050	0.2531527411905001	[151]	[326]	2	hSpCas9	negative selection	11242302
122698903	122698926	7	-	28162770	OCIAML5	viability	GAGAGAGATGCATCTACTCAAGG	RNF133	ENSG00000188050	1.1310596105716066	[257]	[1019]	8	hSpCas9	negative selection	11242303
122698593	122698616	7	-	28162770	OCIAML5	viability	CTTGCACTTATTGAACGGGGAGG	RNF133	ENSG00000188050	-0.6499611636725349	[265]	[305]	-4	hSpCas9	negative selection	11242304
122698373	122698396	7	+	28162770	OCIAML5	viability	CTTTCTCCCCACCTCAACCACGG	RNF133	ENSG00000188050	0.5597661250809298	[506]	[1348]	5	hSpCas9	negative selection	11242305
122698250	122698273	7	-	28162770	OCIAML5	viability	CAAGGATTCAGAACCGGAGATGG	RNF133	ENSG00000188050	0.8027304817213825	[288]	[909]	7	hSpCas9	negative selection	11242306
122698680	122698703	7	-	28162770	EOL1	viability	GGAGTTATAGTGCCACCAGAGGG	RNF133	ENSG00000188050	0.11719284951293041	[727]	[415]	1	hSpCas9	negative selection	11411663
122697777	122697800	7	+	28162770	EOL1	viability	AAGTCATGCCATCAAGGTGAAGG	RNF133	ENSG00000188050	1.7560941573448903	[244]	[435]	9	hSpCas9	negative selection	11411664
122698542	122698565	7	-	28162770	EOL1	viability	GCAACTGAGAAGGGAGCCAGTGG	RNF133	ENSG00000188050	0.837084930320195	[356]	[335]	7	hSpCas9	negative selection	11411665
122698390	122698413	7	-	28162770	EOL1	viability	GGGAGTTCTCATTACAGCCGTGG	RNF133	ENSG00000188050	0.7234501285973148	[268]	[233]	6	hSpCas9	negative selection	11411666
122698856	122698879	7	+	28162770	EOL1	viability	GAACTTCATAAGCCAGGAAGAGG	RNF133	ENSG00000188050	0.869052658978831	[529]	[509]	7	hSpCas9	negative selection	11411667
122698047	122698070	7	-	28162770	EOL1	viability	GACCCCTGGATTTTACCCCATGG	RNF133	ENSG00000188050	0.9453562338504407	[412]	[418]	7	hSpCas9	negative selection	11411668
122698903	122698926	7	-	28162770	EOL1	viability	GAGAGAGATGCATCTACTCAAGG	RNF133	ENSG00000188050	0.130042271779942	[502]	[289]	1	hSpCas9	negative selection	11411669
122698593	122698616	7	-	28162770	EOL1	viability	CTTGCACTTATTGAACGGGGAGG	RNF133	ENSG00000188050	1.8745679224938523	[278]	[538]	9	hSpCas9	negative selection	11411670
122698373	122698396	7	+	28162770	EOL1	viability	CTTTCTCCCCACCTCAACCACGG	RNF133	ENSG00000188050	0.17770244667766955	[927]	[552]	1	hSpCas9	negative selection	11411671
122698250	122698273	7	-	28162770	EOL1	viability	CAAGGATTCAGAACCGGAGATGG	RNF133	ENSG00000188050	-0.11676809754169981	[672]	[326]	-1	hSpCas9	negative selection	11411672
122698680	122698703	7	-	28162770	MOLM13	viability	GGAGTTATAGTGCCACCAGAGGG	RNF133	ENSG00000188050	0.7873701560131983	[471]	[588]	6	hSpCas9	negative selection	11581029
122697777	122697800	7	+	28162770	MOLM13	viability	AAGTCATGCCATCAAGGTGAAGG	RNF133	ENSG00000188050	1.356544405704031	[275]	[510]	9	hSpCas9	negative selection	11581030
122698542	122698565	7	-	28162770	MOLM13	viability	GCAACTGAGAAGGGAGCCAGTGG	RNF133	ENSG00000188050	0.10748713884258077	[284]	[221]	0	hSpCas9	negative selection	11581031
122698390	122698413	7	-	28162770	MOLM13	viability	GGGAGTTCTCATTACAGCCGTGG	RNF133	ENSG00000188050	1.1289829514817056	[202]	[320]	8	hSpCas9	negative selection	11581032
122698856	122698879	7	+	28162770	MOLM13	viability	GAACTTCATAAGCCAGGAAGAGG	RNF133	ENSG00000188050	1.126852463709512	[436]	[689]	8	hSpCas9	negative selection	11581033
122698047	122698070	7	-	28162770	MOLM13	viability	GACCCCTGGATTTTACCCCATGG	RNF133	ENSG00000188050	1.3284231554485464	[330]	[600]	8	hSpCas9	negative selection	11581034
122698903	122698926	7	-	28162770	MOLM13	viability	GAGAGAGATGCATCTACTCAAGG	RNF133	ENSG00000188050	-0.40312417773534315	[555]	[303]	-2	hSpCas9	negative selection	11581035
122698593	122698616	7	-	28162770	MOLM13	viability	CTTGCACTTATTGAACGGGGAGG	RNF133	ENSG00000188050	0.32076250888848545	[360]	[325]	2	hSpCas9	negative selection	11581036
122698373	122698396	7	+	28162770	MOLM13	viability	CTTTCTCCCCACCTCAACCACGG	RNF133	ENSG00000188050	-0.17482988287311452	[1426]	[913]	-1	hSpCas9	negative selection	11581037
122698250	122698273	7	-	28162770	MOLM13	viability	CAAGGATTCAGAACCGGAGATGG	RNF133	ENSG00000188050	0.060505454809170134	[751]	[566]	0	hSpCas9	negative selection	11581038
122698680	122698703	7	-	28162770	HEL	viability	GGAGTTATAGTGCCACCAGAGGG	RNF133	ENSG00000188050	1.137393499342569	[422]	[595]	8	hSpCas9	negative selection	11750395
122697777	122697800	7	+	28162770	HEL	viability	AAGTCATGCCATCAAGGTGAAGG	RNF133	ENSG00000188050	0.8330700441045064	[233]	[266]	7	hSpCas9	negative selection	11750396
122698542	122698565	7	-	28162770	HEL	viability	GCAACTGAGAAGGGAGCCAGTGG	RNF133	ENSG00000188050	0.6804092499664122	[188]	[193]	6	hSpCas9	negative selection	11750397
122698390	122698413	7	-	28162770	HEL	viability	GGGAGTTCTCATTACAGCCGTGG	RNF133	ENSG00000188050	0.021931132332478565	[162]	[105]	0	hSpCas9	negative selection	11750398
122698856	122698879	7	+	28162770	HEL	viability	GAACTTCATAAGCCAGGAAGAGG	RNF133	ENSG00000188050	0.5434885862950445	[360]	[336]	4	hSpCas9	negative selection	11750399
122698047	122698070	7	-	28162770	HEL	viability	GACCCCTGGATTTTACCCCATGG	RNF133	ENSG00000188050	0.255336899635713	[292]	[223]	2	hSpCas9	negative selection	11750400
122698903	122698926	7	-	28162770	HEL	viability	GAGAGAGATGCATCTACTCAAGG	RNF133	ENSG00000188050	0.6027041701981041	[474]	[461]	5	hSpCas9	negative selection	11750401
122698593	122698616	7	-	28162770	HEL	viability	CTTGCACTTATTGAACGGGGAGG	RNF133	ENSG00000188050	0.46779575579142	[323]	[286]	4	hSpCas9	negative selection	11750402
122698373	122698396	7	+	28162770	HEL	viability	CTTTCTCCCCACCTCAACCACGG	RNF133	ENSG00000188050	0.15889217480286177	[1094]	[782]	1	hSpCas9	negative selection	11750403
122698250	122698273	7	-	28162770	HEL	viability	CAAGGATTCAGAACCGGAGATGG	RNF133	ENSG00000188050	-0.5804281907189349	[620]	[265]	-4	hSpCas9	negative selection	11750404
122698680	122698703	7	-	28162770	MV411	viability	GGAGTTATAGTGCCACCAGAGGG	RNF133	ENSG00000188050	0.8845598277161488	[334]	[520]	7	hSpCas9	negative selection	11919761
122697777	122697800	7	+	28162770	MV411	viability	AAGTCATGCCATCAAGGTGAAGG	RNF133	ENSG00000188050	1.077512549340463	[143]	[255]	8	hSpCas9	negative selection	11919762
122698542	122698565	7	-	28162770	MV411	viability	GCAACTGAGAAGGGAGCCAGTGG	RNF133	ENSG00000188050	-0.15761585992344646	[191]	[144]	-1	hSpCas9	negative selection	11919763
122698390	122698413	7	-	28162770	MV411	viability	GGGAGTTCTCATTACAGCCGTGG	RNF133	ENSG00000188050	-0.6967092144837075	[151]	[78]	-5	hSpCas9	negative selection	11919764
122698856	122698879	7	+	28162770	MV411	viability	GAACTTCATAAGCCAGGAAGAGG	RNF133	ENSG00000188050	-0.3931891250533795	[250]	[160]	-3	hSpCas9	negative selection	11919765
122698047	122698070	7	-	28162770	MV411	viability	GACCCCTGGATTTTACCCCATGG	RNF133	ENSG00000188050	0.4117128301594312	[198]	[222]	3	hSpCas9	negative selection	11919766
122698903	122698926	7	-	28162770	MV411	viability	GAGAGAGATGCATCTACTCAAGG	RNF133	ENSG00000188050	0.876254341093359	[323]	[500]	7	hSpCas9	negative selection	11919767
122698593	122698616	7	-	28162770	MV411	viability	CTTGCACTTATTGAACGGGGAGG	RNF133	ENSG00000188050	0.710409527125321	[221]	[305]	6	hSpCas9	negative selection	11919768
122698373	122698396	7	+	28162770	MV411	viability	CTTTCTCCCCACCTCAACCACGG	RNF133	ENSG00000188050	0.44034587022592664	[684]	[782]	4	hSpCas9	negative selection	11919769
122698250	122698273	7	-	28162770	MV411	viability	CAAGGATTCAGAACCGGAGATGG	RNF133	ENSG00000188050	0.291158928212093	[454]	[468]	2	hSpCas9	negative selection	11919770
122698680	122698703	7	-	28162770	MONOMAC1	viability	GGAGTTATAGTGCCACCAGAGGG	RNF133	ENSG00000188050	-0.29085886941607464	[269]	[252]	-3	hSpCas9	negative selection	12089127
122697777	122697800	7	+	28162770	MONOMAC1	viability	AAGTCATGCCATCAAGGTGAAGG	RNF133	ENSG00000188050	-0.49194176818036955	[118]	[96]	-4	hSpCas9	negative selection	12089128
122698542	122698565	7	-	28162770	MONOMAC1	viability	GCAACTGAGAAGGGAGCCAGTGG	RNF133	ENSG00000188050	1.041122890135211	[116]	[275]	8	hSpCas9	negative selection	12089129
122698390	122698413	7	-	28162770	MONOMAC1	viability	GGGAGTTCTCATTACAGCCGTGG	RNF133	ENSG00000188050	0.7820035343048002	[103]	[204]	7	hSpCas9	negative selection	12089130
122698856	122698879	7	+	28162770	MONOMAC1	viability	GAACTTCATAAGCCAGGAAGAGG	RNF133	ENSG00000188050	0.5318008662232521	[177]	[294]	5	hSpCas9	negative selection	12089131
122698047	122698070	7	-	28162770	MONOMAC1	viability	GACCCCTGGATTTTACCCCATGG	RNF133	ENSG00000188050	0.4024252233567176	[131]	[199]	4	hSpCas9	negative selection	12089132
122698903	122698926	7	-	28162770	MONOMAC1	viability	GAGAGAGATGCATCTACTCAAGG	RNF133	ENSG00000188050	0.3879256536616025	[247]	[371]	4	hSpCas9	negative selection	12089133
122698593	122698616	7	-	28162770	MONOMAC1	viability	CTTGCACTTATTGAACGGGGAGG	RNF133	ENSG00000188050	1.0583574965721083	[141]	[338]	8	hSpCas9	negative selection	12089134
122698373	122698396	7	+	28162770	MONOMAC1	viability	CTTTCTCCCCACCTCAACCACGG	RNF133	ENSG00000188050	-0.3215353891774393	[507]	[465]	-3	hSpCas9	negative selection	12089135
122698250	122698273	7	-	28162770	MONOMAC1	viability	CAAGGATTCAGAACCGGAGATGG	RNF133	ENSG00000188050	0.39297888138788784	[284]	[428]	4	hSpCas9	negative selection	12089136
122698680	122698703	7	-	28162770	OCIAML2	viability	GGAGTTATAGTGCCACCAGAGGG	RNF133	ENSG00000188050	0.38210500031945216	[75]	[548]	3	hSpCas9	negative selection	12258493
122697777	122697800	7	+	28162770	OCIAML2	viability	AAGTCATGCCATCAAGGTGAAGG	RNF133	ENSG00000188050	0.10194895102316245	[38]	[231]	1	hSpCas9	negative selection	12258494
122698542	122698565	7	-	28162770	OCIAML2	viability	GCAACTGAGAAGGGAGCCAGTGG	RNF133	ENSG00000188050	0.2111942147315841	[35]	[230]	2	hSpCas9	negative selection	12258495
122698390	122698413	7	-	28162770	OCIAML2	viability	GGGAGTTCTCATTACAGCCGTGG	RNF133	ENSG00000188050	0.6448473921777746	[26]	[233]	6	hSpCas9	negative selection	12258496
122698856	122698879	7	+	28162770	OCIAML2	viability	GAACTTCATAAGCCAGGAAGAGG	RNF133	ENSG00000188050	0.20548056353719024	[68]	[440]	2	hSpCas9	negative selection	12258497
122698047	122698070	7	-	28162770	OCIAML2	viability	GACCCCTGGATTTTACCCCATGG	RNF133	ENSG00000188050	0.26182028780155187	[47]	[318]	2	hSpCas9	negative selection	12258498
122698903	122698926	7	-	28162770	OCIAML2	viability	GAGAGAGATGCATCTACTCAAGG	RNF133	ENSG00000188050	0.11786436644924825	[67]	[408]	1	hSpCas9	negative selection	12258499
122698593	122698616	7	-	28162770	OCIAML2	viability	CTTGCACTTATTGAACGGGGAGG	RNF133	ENSG00000188050	-0.42433617296822634	[45]	[189]	-3	hSpCas9	negative selection	12258500
122698373	122698396	7	+	28162770	OCIAML2	viability	CTTTCTCCCCACCTCAACCACGG	RNF133	ENSG00000188050	0.2695382009623888	[134]	[901]	2	hSpCas9	negative selection	12258501
122698250	122698273	7	-	28162770	OCIAML2	viability	CAAGGATTCAGAACCGGAGATGG	RNF133	ENSG00000188050	-0.34014672916999866	[102]	[450]	-3	hSpCas9	negative selection	12258502
122698680	122698703	7	-	28162770	OCIAML3	viability	GGAGTTATAGTGCCACCAGAGGG	RNF133	ENSG00000188050	-0.01965323916898787	[90]	[270]	0	hSpCas9	negative selection	12427859
122697777	122697800	7	+	28162770	OCIAML3	viability	AAGTCATGCCATCAAGGTGAAGG	RNF133	ENSG00000188050	-0.06676063745929445	[50]	[146]	0	hSpCas9	negative selection	12427860
122698542	122698565	7	-	28162770	OCIAML3	viability	GCAACTGAGAAGGGAGCCAGTGG	RNF133	ENSG00000188050	0.9253665187694162	[44]	[257]	7	hSpCas9	negative selection	12427861
122698390	122698413	7	-	28162770	OCIAML3	viability	GGGAGTTCTCATTACAGCCGTGG	RNF133	ENSG00000188050	-0.10302128781202058	[36]	[103]	-1	hSpCas9	negative selection	12427862
122698856	122698879	7	+	28162770	OCIAML3	viability	GAACTTCATAAGCCAGGAAGAGG	RNF133	ENSG00000188050	0.46827663793017943	[67]	[283]	4	hSpCas9	negative selection	12427863
122698047	122698070	7	-	28162770	OCIAML3	viability	GACCCCTGGATTTTACCCCATGG	RNF133	ENSG00000188050	1.0037789007545765	[55]	[338]	8	hSpCas9	negative selection	12427864
122698903	122698926	7	-	28162770	OCIAML3	viability	GAGAGAGATGCATCTACTCAAGG	RNF133	ENSG00000188050	-0.4840347982990315	[100]	[217]	-4	hSpCas9	negative selection	12427865
122698593	122698616	7	-	28162770	OCIAML3	viability	CTTGCACTTATTGAACGGGGAGG	RNF133	ENSG00000188050	0.12135149765266812	[73]	[242]	1	hSpCas9	negative selection	12427866
122698373	122698396	7	+	28162770	OCIAML3	viability	CTTTCTCCCCACCTCAACCACGG	RNF133	ENSG00000188050	0.5126678933466131	[214]	[925]	5	hSpCas9	negative selection	12427867
122698250	122698273	7	-	28162770	OCIAML3	viability	CAAGGATTCAGAACCGGAGATGG	RNF133	ENSG00000188050	-0.30001642193992395	[145]	[357]	-2	hSpCas9	negative selection	12427868