Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:6195
• Symbol:RPS6KA1
• Description:ribosomal protein S6 kinase A1

DataSource: http://genomecrispr.dkfz.de/#!/results/RPS6KA1

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
26557006	26557029	CHR_HG2058_PATCH	-	26472758	Jiyoye	viability	AGGGTGGCTTGATCTCACGACGG	RPS6KA1	ENSG00000281877	0.6406655117256519	[147]	[173]	5	hSpCas9	negative selection	140212
26557006	26557029	1	-	26472758	Jiyoye	viability	AGGGTGGCTTGATCTCACGACGG	RPS6KA1	ENSG00000117676	0.6406655117256519	[147]	[173]	5	hSpCas9	negative selection	140213
26558823	26558846	CHR_HG2058_PATCH	-	26472758	Jiyoye	viability	GCTGATGGGCCCCAGCGCTGGGG	RPS6KA1	ENSG00000281877	-1.3335817918227069	[126]	[37]	-7	hSpCas9	negative selection	140214
26558823	26558846	1	-	26472758	Jiyoye	viability	GCTGATGGGCCCCAGCGCTGGGG	RPS6KA1	ENSG00000117676	-1.3335817918227069	[126]	[37]	-7	hSpCas9	negative selection	140215
26547204	26547227	1	+	26472758	Jiyoye	viability	AAAGTCACCCGGCCTGACAGTGG	RPS6KA1	ENSG00000117676	-0.6284485282248478	[40]	[19]	-4	hSpCas9	negative selection	140216
26547204	26547227	CHR_HG2058_PATCH	+	26472758	Jiyoye	viability	AAAGTCACCCGGCCTGACAGTGG	RPS6KA1	ENSG00000281877	-0.6284485282248478	[40]	[19]	-4	hSpCas9	negative selection	140217
26553384	26553407	1	+	26472758	Jiyoye	viability	TTTGCAGGTGATGTTCACGGAGG	RPS6KA1	ENSG00000117676	-0.08443664288057373	[186]	[132]	0	hSpCas9	negative selection	140218
26553384	26553407	CHR_HG2058_PATCH	+	26472758	Jiyoye	viability	TTTGCAGGTGATGTTCACGGAGG	RPS6KA1	ENSG00000281877	-0.08443664288057373	[186]	[132]	0	hSpCas9	negative selection	140219
26557022	26557045	1	-	26472758	Jiyoye	viability	GCCACTGCTGGCTTGAAGGGTGG	RPS6KA1	ENSG00000117676	0.16293857112620563	[121]	[102]	1	hSpCas9	negative selection	140220
26557022	26557045	CHR_HG2058_PATCH	-	26472758	Jiyoye	viability	GCCACTGCTGGCTTGAAGGGTGG	RPS6KA1	ENSG00000281877	0.16293857112620563	[121]	[102]	1	hSpCas9	negative selection	140221
26558910	26558933	CHR_HG2058_PATCH	+	26472758	Jiyoye	viability	GCAGGCACCCCTGCACTCGGTGG	RPS6KA1	ENSG00000281877	0.5105531213511821	[174]	[187]	4	hSpCas9	negative selection	140222
26558910	26558933	1	+	26472758	Jiyoye	viability	GCAGGCACCCCTGCACTCGGTGG	RPS6KA1	ENSG00000117676	0.5105531213511821	[174]	[187]	4	hSpCas9	negative selection	140223
26561535	26561558	CHR_HG2058_PATCH	+	26472758	Jiyoye	viability	GTGACAGAGCTGATGCGGGGTGG	RPS6KA1	ENSG00000281877	-0.7682666249040047	[130]	[57]	-5	hSpCas9	negative selection	140224
26561535	26561558	1	+	26472758	Jiyoye	viability	GTGACAGAGCTGATGCGGGGTGG	RPS6KA1	ENSG00000117676	-0.7682666249040047	[130]	[57]	-5	hSpCas9	negative selection	140225
26561585	26561608	1	+	26472758	Jiyoye	viability	GAAGTTCTTCTCAGAGCGGGAGG	RPS6KA1	ENSG00000117676	0.3719859530435735	[82]	[80]	3	hSpCas9	negative selection	140226
26561585	26561608	CHR_HG2058_PATCH	+	26472758	Jiyoye	viability	GAAGTTCTTCTCAGAGCGGGAGG	RPS6KA1	ENSG00000281877	0.3719859530435735	[82]	[80]	3	hSpCas9	negative selection	140227
26555164	26555187	CHR_HG2058_PATCH	+	26472758	Jiyoye	viability	CGGGCTCCCTGCCCTTCCAGGGG	RPS6KA1	ENSG00000281877	-0.518185817601371	[225]	[118]	-4	hSpCas9	negative selection	140228
26555164	26555187	1	+	26472758	Jiyoye	viability	CGGGCTCCCTGCCCTTCCAGGGG	RPS6KA1	ENSG00000117676	-0.518185817601371	[225]	[118]	-4	hSpCas9	negative selection	140229
26555553	26555576	CHR_HG2058_PATCH	-	26472758	Jiyoye	viability	GCTTCAGTGCTCAGAAACTGGGG	RPS6KA1	ENSG00000281877	-0.536241090127759	[124]	[64]	-4	hSpCas9	negative selection	140230
26555553	26555576	1	-	26472758	Jiyoye	viability	GCTTCAGTGCTCAGAAACTGGGG	RPS6KA1	ENSG00000117676	-0.536241090127759	[124]	[64]	-4	hSpCas9	negative selection	140231
26557006	26557029	CHR_HG2058_PATCH	-	26472758	KBM7	viability	AGGGTGGCTTGATCTCACGACGG	RPS6KA1	ENSG00000281877	-0.5944847460477657	[868,540]	[245,187]	-5	hSpCas9	negative selection	331330
26557006	26557029	1	-	26472758	KBM7	viability	AGGGTGGCTTGATCTCACGACGG	RPS6KA1	ENSG00000117676	-0.5944847460477657	[868,540]	[245,187]	-5	hSpCas9	negative selection	331331
26558823	26558846	CHR_HG2058_PATCH	-	26472758	KBM7	viability	GCTGATGGGCCCCAGCGCTGGGG	RPS6KA1	ENSG00000281877	-1.411469047047144	[281,156]	[49,26]	-7	hSpCas9	negative selection	331332
26558823	26558846	1	-	26472758	KBM7	viability	GCTGATGGGCCCCAGCGCTGGGG	RPS6KA1	ENSG00000117676	-1.411469047047144	[281,156]	[49,26]	-7	hSpCas9	negative selection	331333
26547204	26547227	1	+	26472758	KBM7	viability	AAAGTCACCCGGCCTGACAGTGG	RPS6KA1	ENSG00000117676	-0.37072597310651223	[168,113]	[84,19]	-3	hSpCas9	negative selection	331334
26547204	26547227	CHR_HG2058_PATCH	+	26472758	KBM7	viability	AAAGTCACCCGGCCTGACAGTGG	RPS6KA1	ENSG00000281877	-0.37072597310651223	[168,113]	[84,19]	-3	hSpCas9	negative selection	331335
26553384	26553407	1	+	26472758	KBM7	viability	TTTGCAGGTGATGTTCACGGAGG	RPS6KA1	ENSG00000117676	0.19008477260032675	[844,698]	[409,413]	2	hSpCas9	negative selection	331336
26553384	26553407	CHR_HG2058_PATCH	+	26472758	KBM7	viability	TTTGCAGGTGATGTTCACGGAGG	RPS6KA1	ENSG00000281877	0.19008477260032675	[844,698]	[409,413]	2	hSpCas9	negative selection	331337
26557022	26557045	1	-	26472758	KBM7	viability	GCCACTGCTGGCTTGAAGGGTGG	RPS6KA1	ENSG00000117676	-0.25763997186678855	[587,372]	[221,152]	-2	hSpCas9	negative selection	331338
26557022	26557045	CHR_HG2058_PATCH	-	26472758	KBM7	viability	GCCACTGCTGGCTTGAAGGGTGG	RPS6KA1	ENSG00000281877	-0.25763997186678855	[587,372]	[221,152]	-2	hSpCas9	negative selection	331339
26558910	26558933	CHR_HG2058_PATCH	+	26472758	KBM7	viability	GCAGGCACCCCTGCACTCGGTGG	RPS6KA1	ENSG00000281877	0.5007539048021028	[784,387]	[376,379]	5	hSpCas9	negative selection	331340
26558910	26558933	1	+	26472758	KBM7	viability	GCAGGCACCCCTGCACTCGGTGG	RPS6KA1	ENSG00000117676	0.5007539048021028	[784,387]	[376,379]	5	hSpCas9	negative selection	331341
26561535	26561558	CHR_HG2058_PATCH	+	26472758	KBM7	viability	GTGACAGAGCTGATGCGGGGTGG	RPS6KA1	ENSG00000281877	-0.26937034842922347	[618,378]	[146,229]	-3	hSpCas9	negative selection	331342
26561535	26561558	1	+	26472758	KBM7	viability	GTGACAGAGCTGATGCGGGGTGG	RPS6KA1	ENSG00000117676	-0.26937034842922347	[618,378]	[146,229]	-3	hSpCas9	negative selection	331343
26561585	26561608	1	+	26472758	KBM7	viability	GAAGTTCTTCTCAGAGCGGGAGG	RPS6KA1	ENSG00000117676	-0.6610006428362236	[473,285]	[125,96]	-5	hSpCas9	negative selection	331344
26561585	26561608	CHR_HG2058_PATCH	+	26472758	KBM7	viability	GAAGTTCTTCTCAGAGCGGGAGG	RPS6KA1	ENSG00000281877	-0.6610006428362236	[473,285]	[125,96]	-5	hSpCas9	negative selection	331345
26555164	26555187	CHR_HG2058_PATCH	+	26472758	KBM7	viability	CGGGCTCCCTGCCCTTCCAGGGG	RPS6KA1	ENSG00000281877	0.06792729939950504	[1000,875]	[373,539]	0	hSpCas9	negative selection	331346
26555164	26555187	1	+	26472758	KBM7	viability	CGGGCTCCCTGCCCTTCCAGGGG	RPS6KA1	ENSG00000117676	0.06792729939950504	[1000,875]	[373,539]	0	hSpCas9	negative selection	331347
26555553	26555576	CHR_HG2058_PATCH	-	26472758	KBM7	viability	GCTTCAGTGCTCAGAAACTGGGG	RPS6KA1	ENSG00000281877	0.603565490188001	[218,209]	[244,71]	6	hSpCas9	negative selection	331348
26555553	26555576	1	-	26472758	KBM7	viability	GCTTCAGTGCTCAGAAACTGGGG	RPS6KA1	ENSG00000117676	0.603565490188001	[218,209]	[244,71]	6	hSpCas9	negative selection	331349
26557006	26557029	CHR_HG2058_PATCH	-	26472758	Raji	viability	AGGGTGGCTTGATCTCACGACGG	RPS6KA1	ENSG00000281877	0.27836973218622235	[301]	[84]	2	hSpCas9	negative selection	522448
26557006	26557029	1	-	26472758	Raji	viability	AGGGTGGCTTGATCTCACGACGG	RPS6KA1	ENSG00000117676	0.27836973218622235	[301]	[84]	2	hSpCas9	negative selection	522449
26558823	26558846	CHR_HG2058_PATCH	-	26472758	Raji	viability	GCTGATGGGCCCCAGCGCTGGGG	RPS6KA1	ENSG00000281877	-0.5930561827674927	[168]	[25]	-5	hSpCas9	negative selection	522450
26558823	26558846	1	-	26472758	Raji	viability	GCTGATGGGCCCCAGCGCTGGGG	RPS6KA1	ENSG00000117676	-0.5930561827674927	[168]	[25]	-5	hSpCas9	negative selection	522451
26547204	26547227	1	+	26472758	Raji	viability	AAAGTCACCCGGCCTGACAGTGG	RPS6KA1	ENSG00000117676	0.8411034700361515	[88]	[36]	7	hSpCas9	negative selection	522452
26547204	26547227	CHR_HG2058_PATCH	+	26472758	Raji	viability	AAAGTCACCCGGCCTGACAGTGG	RPS6KA1	ENSG00000281877	0.8411034700361515	[88]	[36]	7	hSpCas9	negative selection	522453
26553384	26553407	1	+	26472758	Raji	viability	TTTGCAGGTGATGTTCACGGAGG	RPS6KA1	ENSG00000117676	-0.29651340630004386	[343]	[64]	-2	hSpCas9	negative selection	522454
26553384	26553407	CHR_HG2058_PATCH	+	26472758	Raji	viability	TTTGCAGGTGATGTTCACGGAGG	RPS6KA1	ENSG00000281877	-0.29651340630004386	[343]	[64]	-2	hSpCas9	negative selection	522455
26557022	26557045	1	-	26472758	Raji	viability	GCCACTGCTGGCTTGAAGGGTGG	RPS6KA1	ENSG00000117676	-0.07641364065027048	[208]	[45]	0	hSpCas9	negative selection	522456
26557022	26557045	CHR_HG2058_PATCH	-	26472758	Raji	viability	GCCACTGCTGGCTTGAAGGGTGG	RPS6KA1	ENSG00000281877	-0.07641364065027048	[208]	[45]	0	hSpCas9	negative selection	522457
26558910	26558933	CHR_HG2058_PATCH	+	26472758	Raji	viability	GCAGGCACCCCTGCACTCGGTGG	RPS6KA1	ENSG00000281877	1.1021278099221041	[274]	[136]	8	hSpCas9	negative selection	522458
26558910	26558933	1	+	26472758	Raji	viability	GCAGGCACCCCTGCACTCGGTGG	RPS6KA1	ENSG00000117676	1.1021278099221041	[274]	[136]	8	hSpCas9	negative selection	522459
26561535	26561558	CHR_HG2058_PATCH	+	26472758	Raji	viability	GTGACAGAGCTGATGCGGGGTGG	RPS6KA1	ENSG00000281877	-0.4415097106400348	[315]	[53]	-4	hSpCas9	negative selection	522460
26561535	26561558	1	+	26472758	Raji	viability	GTGACAGAGCTGATGCGGGGTGG	RPS6KA1	ENSG00000117676	-0.4415097106400348	[315]	[53]	-4	hSpCas9	negative selection	522461
26561585	26561608	1	+	26472758	Raji	viability	GAAGTTCTTCTCAGAGCGGGAGG	RPS6KA1	ENSG00000117676	-1.3706637614310446	[233]	[20]	-7	hSpCas9	negative selection	522462
26561585	26561608	CHR_HG2058_PATCH	+	26472758	Raji	viability	GAAGTTCTTCTCAGAGCGGGAGG	RPS6KA1	ENSG00000281877	-1.3706637614310446	[233]	[20]	-7	hSpCas9	negative selection	522463
26555164	26555187	CHR_HG2058_PATCH	+	26472758	Raji	viability	CGGGCTCCCTGCCCTTCCAGGGG	RPS6KA1	ENSG00000281877	-1.0133686240870108	[547]	[62]	-6	hSpCas9	negative selection	522464
26555164	26555187	1	+	26472758	Raji	viability	CGGGCTCCCTGCCCTTCCAGGGG	RPS6KA1	ENSG00000117676	-1.0133686240870108	[547]	[62]	-6	hSpCas9	negative selection	522465
26555553	26555576	CHR_HG2058_PATCH	-	26472758	Raji	viability	GCTTCAGTGCTCAGAAACTGGGG	RPS6KA1	ENSG00000281877	0.9769868981179246	[80]	[36]	8	hSpCas9	negative selection	522466
26555553	26555576	1	-	26472758	Raji	viability	GCTTCAGTGCTCAGAAACTGGGG	RPS6KA1	ENSG00000117676	0.9769868981179246	[80]	[36]	8	hSpCas9	negative selection	522467
26557006	26557029	CHR_HG2058_PATCH	-	26472758	K562	viability	AGGGTGGCTTGATCTCACGACGG	RPS6KA1	ENSG00000281877	0.19265729997670542	[453]	[437]	1	hSpCas9	negative selection	713566
26557006	26557029	1	-	26472758	K562	viability	AGGGTGGCTTGATCTCACGACGG	RPS6KA1	ENSG00000117676	0.19265729997670542	[453]	[437]	1	hSpCas9	negative selection	713567
26558823	26558846	CHR_HG2058_PATCH	-	26472758	K562	viability	GCTGATGGGCCCCAGCGCTGGGG	RPS6KA1	ENSG00000281877	-0.4513242037732461	[114]	[70]	-3	hSpCas9	negative selection	713568
26558823	26558846	1	-	26472758	K562	viability	GCTGATGGGCCCCAGCGCTGGGG	RPS6KA1	ENSG00000117676	-0.4513242037732461	[114]	[70]	-3	hSpCas9	negative selection	713569
26547204	26547227	1	+	26472758	K562	viability	AAAGTCACCCGGCCTGACAGTGG	RPS6KA1	ENSG00000117676	-0.19918792380916783	[135]	[99]	-1	hSpCas9	negative selection	713570
26547204	26547227	CHR_HG2058_PATCH	+	26472758	K562	viability	AAAGTCACCCGGCCTGACAGTGG	RPS6KA1	ENSG00000281877	-0.19918792380916783	[135]	[99]	-1	hSpCas9	negative selection	713571
26553384	26553407	1	+	26472758	K562	viability	TTTGCAGGTGATGTTCACGGAGG	RPS6KA1	ENSG00000117676	0.608258449869074	[630]	[811]	5	hSpCas9	negative selection	713572
26553384	26553407	CHR_HG2058_PATCH	+	26472758	K562	viability	TTTGCAGGTGATGTTCACGGAGG	RPS6KA1	ENSG00000281877	0.608258449869074	[630]	[811]	5	hSpCas9	negative selection	713573
26557022	26557045	1	-	26472758	K562	viability	GCCACTGCTGGCTTGAAGGGTGG	RPS6KA1	ENSG00000117676	-0.26273697360082826	[387]	[272]	-2	hSpCas9	negative selection	713574
26557022	26557045	CHR_HG2058_PATCH	-	26472758	K562	viability	GCCACTGCTGGCTTGAAGGGTGG	RPS6KA1	ENSG00000281877	-0.26273697360082826	[387]	[272]	-2	hSpCas9	negative selection	713575
26558910	26558933	CHR_HG2058_PATCH	+	26472758	K562	viability	GCAGGCACCCCTGCACTCGGTGG	RPS6KA1	ENSG00000281877	0.09695139600207386	[493]	[445]	0	hSpCas9	negative selection	713576
26558910	26558933	1	+	26472758	K562	viability	GCAGGCACCCCTGCACTCGGTGG	RPS6KA1	ENSG00000117676	0.09695139600207386	[493]	[445]	0	hSpCas9	negative selection	713577
26561535	26561558	CHR_HG2058_PATCH	+	26472758	K562	viability	GTGACAGAGCTGATGCGGGGTGG	RPS6KA1	ENSG00000281877	0.5794424801654925	[328]	[414]	5	hSpCas9	negative selection	713578
26561535	26561558	1	+	26472758	K562	viability	GTGACAGAGCTGATGCGGGGTGG	RPS6KA1	ENSG00000117676	0.5794424801654925	[328]	[414]	5	hSpCas9	negative selection	713579
26561585	26561608	1	+	26472758	K562	viability	GAAGTTCTTCTCAGAGCGGGAGG	RPS6KA1	ENSG00000117676	0.16806784153633197	[290]	[275]	1	hSpCas9	negative selection	713580
26561585	26561608	CHR_HG2058_PATCH	+	26472758	K562	viability	GAAGTTCTTCTCAGAGCGGGAGG	RPS6KA1	ENSG00000281877	0.16806784153633197	[290]	[275]	1	hSpCas9	negative selection	713581
26555164	26555187	CHR_HG2058_PATCH	+	26472758	K562	viability	CGGGCTCCCTGCCCTTCCAGGGG	RPS6KA1	ENSG00000281877	-1.60041089980982	[818]	[227]	-7	hSpCas9	negative selection	713582
26555164	26555187	1	+	26472758	K562	viability	CGGGCTCCCTGCCCTTCCAGGGG	RPS6KA1	ENSG00000117676	-1.60041089980982	[818]	[227]	-7	hSpCas9	negative selection	713583
26555553	26555576	CHR_HG2058_PATCH	-	26472758	K562	viability	GCTTCAGTGCTCAGAAACTGGGG	RPS6KA1	ENSG00000281877	0.5479682932389546	[157]	[194]	4	hSpCas9	negative selection	713584
26555553	26555576	1	-	26472758	K562	viability	GCTTCAGTGCTCAGAAACTGGGG	RPS6KA1	ENSG00000117676	0.5479682932389546	[157]	[194]	4	hSpCas9	negative selection	713585
26529946	26529969	1	-	26627737	DLD1	viability	CACTAGCTCCATGAGCGGCCAGG	RPS6KA1	ENSG00000117676	1.2992242009574266	[99]	[64,69,92]	9	hSpCas9	negative selection	770444
26543207	26543230	1	-	26627737	DLD1	viability	CTGCTCACCTTTCTGGGACAGGG	RPS6KA1	ENSG00000117676	-0.38281790217121014	[1080]	[255,223,290]	-4	hSpCas9	negative selection	770445
26544153	26544176	1	-	26627737	DLD1	viability	GGGCAGATAGGTCTGACACCTGG	RPS6KA1	ENSG00000117676	0.11163564483898658	[212]	[159,27,31]	1	hSpCas9	negative selection	770446
26546023	26546046	1	-	26627737	DLD1	viability	GCACACTCACCGAGTCCCGCTGG	RPS6KA1	ENSG00000117676	0.676387779328433	[343]	[80,273,165]	6	hSpCas9	negative selection	770447
26546894	26546917	1	+	26627737	DLD1	viability	ATCACGCACCACGTCAAGGCTGG	RPS6KA1	ENSG00000117676	0.5849056862149464	[517]	[393,156,182]	6	hSpCas9	negative selection	770448
26551404	26551427	1	-	26627737	DLD1	viability	TCTCCATCTTGGTCCGGACGCGG	RPS6KA1	ENSG00000117676	-0.17146962348251138	[408]	[140,117,85]	-2	hSpCas9	negative selection	770449
26529946	26529969	1	-	26627737	GBM cells	viability after 5 days	CACTAGCTCCATGAGCGGCCAGG	RPS6KA1	ENSG00000117676	-0.8219320539172438	[177]	[77,29]	-8	hSpCas9	negative selection	852759
26543207	26543230	1	-	26627737	GBM cells	viability after 5 days	CTGCTCACCTTTCTGGGACAGGG	RPS6KA1	ENSG00000117676	0.07830285612581456	[573]	[307,341]	1	hSpCas9	negative selection	852760
26544153	26544176	1	-	26627737	GBM cells	viability after 5 days	GGGCAGATAGGTCTGACACCTGG	RPS6KA1	ENSG00000117676	-0.08459800232574577	[86]	[57,29]	-1	hSpCas9	negative selection	852761
26546023	26546046	1	-	26627737	GBM cells	viability after 5 days	GCACACTCACCGAGTCCCGCTGG	RPS6KA1	ENSG00000117676	0.5180090605259878	[180]	[110,166]	7	hSpCas9	negative selection	852762
26546894	26546917	1	+	26627737	GBM cells	viability after 5 days	ATCACGCACCACGTCAAGGCTGG	RPS6KA1	ENSG00000117676	0.09745955426776604	[304]	[181,167]	1	hSpCas9	negative selection	852763
26551404	26551427	1	-	26627737	GBM cells	viability after 5 days	TCTCCATCTTGGTCCGGACGCGG	RPS6KA1	ENSG00000117676	0.3438284154991452	[226]	[135,172]	5	hSpCas9	negative selection	852764
26529946	26529969	1	-	26627737	GBM cells	viability after 13 days	CACTAGCTCCATGAGCGGCCAGG	RPS6KA1	ENSG00000117676	-1.258765524663732	[177]	[73,12]	-8	hSpCas9	negative selection	935074
26543207	26543230	1	-	26627737	GBM cells	viability after 13 days	CTGCTCACCTTTCTGGGACAGGG	RPS6KA1	ENSG00000117676	0.18369256954048918	[573]	[436,285]	2	hSpCas9	negative selection	935075
26544153	26544176	1	-	26627737	GBM cells	viability after 13 days	GGGCAGATAGGTCTGACACCTGG	RPS6KA1	ENSG00000117676	-0.7079896163746515	[86]	[29,27]	-7	hSpCas9	negative selection	935076
26546023	26546046	1	-	26627737	GBM cells	viability after 13 days	GCACACTCACCGAGTCCCGCTGG	RPS6KA1	ENSG00000117676	0.288882606431373	[180]	[146,97]	3	hSpCas9	negative selection	935077
26546894	26546917	1	+	26627737	GBM cells	viability after 13 days	ATCACGCACCACGTCAAGGCTGG	RPS6KA1	ENSG00000117676	-0.316077691806521	[304]	[197,79]	-4	hSpCas9	negative selection	935078
26551404	26551427	1	-	26627737	GBM cells	viability after 13 days	TCTCCATCTTGGTCCGGACGCGG	RPS6KA1	ENSG00000117676	0.25052870408614947	[226]	[156,137]	3	hSpCas9	negative selection	935079
26529946	26529969	1	-	26627737	GBM cells	viability after 21 days	CACTAGCTCCATGAGCGGCCAGG	RPS6KA1	ENSG00000117676	-1.5895013907292963	[177]	[28,34]	-8	hSpCas9	negative selection	1017389
26543207	26543230	1	-	26627737	GBM cells	viability after 21 days	CTGCTCACCTTTCTGGGACAGGG	RPS6KA1	ENSG00000117676	0.0815514327333513	[573]	[353,307]	0	hSpCas9	negative selection	1017390
26544153	26544176	1	-	26627737	GBM cells	viability after 21 days	GGGCAGATAGGTCTGACACCTGG	RPS6KA1	ENSG00000117676	-0.4407738280901643	[86]	[38,30]	-4	hSpCas9	negative selection	1017391
26546023	26546046	1	-	26627737	GBM cells	viability after 21 days	GCACACTCACCGAGTCCCGCTGG	RPS6KA1	ENSG00000117676	0.7462237890767962	[180]	[177,152]	7	hSpCas9	negative selection	1017392
26546894	26546917	1	+	26627737	GBM cells	viability after 21 days	ATCACGCACCACGTCAAGGCTGG	RPS6KA1	ENSG00000117676	-1.2814376006139974	[304]	[75,60]	-8	hSpCas9	negative selection	1017393
26551404	26551427	1	-	26627737	GBM cells	viability after 21 days	TCTCCATCTTGGTCCGGACGCGG	RPS6KA1	ENSG00000117676	0.007363935023380883	[226]	[124,122]	0	hSpCas9	negative selection	1017394
26529946	26529969	1	-	26627737	RPE1	viability after 9 days	CACTAGCTCCATGAGCGGCCAGG	RPS6KA1	ENSG00000117676	1.160799398725083	[313]	[114,354]	7	hSpCas9	negative selection	1099704
26543207	26543230	1	-	26627737	RPE1	viability after 9 days	CTGCTCACCTTTCTGGGACAGGG	RPS6KA1	ENSG00000117676	0.6068733794433512	[1419]	[356,1089]	4	hSpCas9	negative selection	1099705
26544153	26544176	1	-	26627737	RPE1	viability after 9 days	GGGCAGATAGGTCTGACACCTGG	RPS6KA1	ENSG00000117676	-0.37028970447889076	[514]	[177,55]	-3	hSpCas9	negative selection	1099706
26546023	26546046	1	-	26627737	RPE1	viability after 9 days	GCACACTCACCGAGTCCCGCTGG	RPS6KA1	ENSG00000117676	1.3011745680829403	[66]	[52,49]	7	hSpCas9	negative selection	1099707
26546894	26546917	1	+	26627737	RPE1	viability after 9 days	ATCACGCACCACGTCAAGGCTGG	RPS6KA1	ENSG00000117676	3.534158154604908	[92]	[266,427]	9	hSpCas9	negative selection	1099708
26551404	26551427	1	-	26627737	RPE1	viability after 9 days	TCTCCATCTTGGTCCGGACGCGG	RPS6KA1	ENSG00000117676	1.18056392476145	[328]	[91,415]	7	hSpCas9	negative selection	1099709
26529946	26529969	1	-	26627737	RPE1	viability after 12 days	CACTAGCTCCATGAGCGGCCAGG	RPS6KA1	ENSG00000117676	0.9605499233690682	[313]	[152,175]	6	hSpCas9	negative selection	1182019
26543207	26543230	1	-	26627737	RPE1	viability after 12 days	CTGCTCACCTTTCTGGGACAGGG	RPS6KA1	ENSG00000117676	0.3655257357267443	[1419]	[372,616]	2	hSpCas9	negative selection	1182020
26544153	26544176	1	-	26627737	RPE1	viability after 12 days	GGGCAGATAGGTCTGACACCTGG	RPS6KA1	ENSG00000117676	-1.2261851749557215	[514]	[63,53]	-7	hSpCas9	negative selection	1182021
26546023	26546046	1	-	26627737	RPE1	viability after 12 days	GCACACTCACCGAGTCCCGCTGG	RPS6KA1	ENSG00000117676	0.6329539562387843	[66]	[24,30]	4	hSpCas9	negative selection	1182022
26546894	26546917	1	+	26627737	RPE1	viability after 12 days	ATCACGCACCACGTCAAGGCTGG	RPS6KA1	ENSG00000117676	3.5264481645757946	[92]	[284,290]	9	hSpCas9	negative selection	1182023
26551404	26551427	1	-	26627737	RPE1	viability after 12 days	TCTCCATCTTGGTCCGGACGCGG	RPS6KA1	ENSG00000117676	0.7869682111348962	[328]	[186,115]	5	hSpCas9	negative selection	1182024
26529946	26529969	1	-	26627737	RPE1	viability after 15 days	CACTAGCTCCATGAGCGGCCAGG	RPS6KA1	ENSG00000117676	0.8182102529148705	[313]	[121,189]	5	hSpCas9	negative selection	1264334
26543207	26543230	1	-	26627737	RPE1	viability after 15 days	CTGCTCACCTTTCTGGGACAGGG	RPS6KA1	ENSG00000117676	-0.0896021527334323	[1419]	[236,512]	0	hSpCas9	negative selection	1264335
26544153	26544176	1	-	26627737	RPE1	viability after 15 days	GGGCAGATAGGTCTGACACCTGG	RPS6KA1	ENSG00000117676	-1.7869209418509966	[514]	[29,53]	-8	hSpCas9	negative selection	1264336
26546023	26546046	1	-	26627737	RPE1	viability after 15 days	GCACACTCACCGAGTCCCGCTGG	RPS6KA1	ENSG00000117676	0.17156392651049845	[66]	[29,12]	1	hSpCas9	negative selection	1264337
26546894	26546917	1	+	26627737	RPE1	viability after 15 days	ATCACGCACCACGTCAAGGCTGG	RPS6KA1	ENSG00000117676	3.420415779379248	[92]	[159,398]	9	hSpCas9	negative selection	1264338
26551404	26551427	1	-	26627737	RPE1	viability after 15 days	TCTCCATCTTGGTCCGGACGCGG	RPS6KA1	ENSG00000117676	0.23991801443728344	[328]	[58,158]	1	hSpCas9	negative selection	1264339
26529946	26529969	1	-	26627737	RPE1	viability after 18 days	CACTAGCTCCATGAGCGGCCAGG	RPS6KA1	ENSG00000117676	0.9252847343733117	[313]	[114,209]	5	hSpCas9	negative selection	1346649
26543207	26543230	1	-	26627737	RPE1	viability after 18 days	CTGCTCACCTTTCTGGGACAGGG	RPS6KA1	ENSG00000117676	0.3729335603497075	[1419]	[357,643]	2	hSpCas9	negative selection	1346650
26544153	26544176	1	-	26627737	RPE1	viability after 18 days	GGGCAGATAGGTCTGACACCTGG	RPS6KA1	ENSG00000117676	-1.2525508223434785	[514]	[67,47]	-6	hSpCas9	negative selection	1346651
26546023	26546046	1	-	26627737	RPE1	viability after 18 days	GCACACTCACCGAGTCCCGCTGG	RPS6KA1	ENSG00000117676	1.0595819224980714	[66]	[13,62]	6	hSpCas9	negative selection	1346652
26546894	26546917	1	+	26627737	RPE1	viability after 18 days	ATCACGCACCACGTCAAGGCTGG	RPS6KA1	ENSG00000117676	2.9300130681713656	[92]	[140,244]	9	hSpCas9	negative selection	1346653
26551404	26551427	1	-	26627737	RPE1	viability after 18 days	TCTCCATCTTGGTCCGGACGCGG	RPS6KA1	ENSG00000117676	0.6487300634180524	[328]	[144,132]	4	hSpCas9	negative selection	1346654
26529946	26529969	1	-	26627737	HeLa	viability after 8 days	CACTAGCTCCATGAGCGGCCAGG	RPS6KA1	ENSG00000117676	0.7717153972165728	[268]	[239,14,342]	6	hSpCas9	negative selection	1428964
26543207	26543230	1	-	26627737	HeLa	viability after 8 days	CTGCTCACCTTTCTGGGACAGGG	RPS6KA1	ENSG00000117676	-0.4158055557383372	[1044]	[341,401,282]	-4	hSpCas9	negative selection	1428965
26544153	26544176	1	-	26627737	HeLa	viability after 8 days	GGGCAGATAGGTCTGACACCTGG	RPS6KA1	ENSG00000117676	0.09466816310609305	[136]	[138,55,15]	0	hSpCas9	negative selection	1428966
26546023	26546046	1	-	26627737	HeLa	viability after 8 days	GCACACTCACCGAGTCCCGCTGG	RPS6KA1	ENSG00000117676	-0.27679054851279505	[354]	[170,32,183]	-3	hSpCas9	negative selection	1428967
26546894	26546917	1	+	26627737	HeLa	viability after 8 days	ATCACGCACCACGTCAAGGCTGG	RPS6KA1	ENSG00000117676	0.6082489847071806	[266]	[156,223,147]	5	hSpCas9	negative selection	1428968
26551404	26551427	1	-	26627737	HeLa	viability after 8 days	TCTCCATCTTGGTCCGGACGCGG	RPS6KA1	ENSG00000117676	-0.18205646610859771	[277]	[144,145,41]	-2	hSpCas9	negative selection	1428969
26529946	26529969	1	-	26627737	HeLa	viability after 12 days	CACTAGCTCCATGAGCGGCCAGG	RPS6KA1	ENSG00000117676	0.014950990115050411	[268]	[27,88,219]	0	hSpCas9	negative selection	1511279
26543207	26543230	1	-	26627737	HeLa	viability after 12 days	CTGCTCACCTTTCTGGGACAGGG	RPS6KA1	ENSG00000117676	0.41397991153143265	[1044]	[588,410,743]	3	hSpCas9	negative selection	1511280
26544153	26544176	1	-	26627737	HeLa	viability after 12 days	GGGCAGATAGGTCTGACACCTGG	RPS6KA1	ENSG00000117676	-0.21377159105659094	[136]	[29,47,67]	-2	hSpCas9	negative selection	1511281
26546023	26546046	1	-	26627737	HeLa	viability after 12 days	GCACACTCACCGAGTCCCGCTGG	RPS6KA1	ENSG00000117676	-1.062331211513783	[354]	[155,15,46]	-7	hSpCas9	negative selection	1511282
26546894	26546917	1	+	26627737	HeLa	viability after 12 days	ATCACGCACCACGTCAAGGCTGG	RPS6KA1	ENSG00000117676	0.43696055796810596	[266]	[224,142,82]	4	hSpCas9	negative selection	1511283
26551404	26551427	1	-	26627737	HeLa	viability after 12 days	TCTCCATCTTGGTCCGGACGCGG	RPS6KA1	ENSG00000117676	0.4151775687671999	[277]	[69,135,252]	3	hSpCas9	negative selection	1511284
26529946	26529969	1	-	26627737	HeLa	viability after 15 days	CACTAGCTCCATGAGCGGCCAGG	RPS6KA1	ENSG00000117676	-0.5908835819796486	[268]	[22,83,114]	-5	hSpCas9	negative selection	1593594
26543207	26543230	1	-	26627737	HeLa	viability after 15 days	CTGCTCACCTTTCTGGGACAGGG	RPS6KA1	ENSG00000117676	0.0860775769968174	[1044]	[360,360,648]	0	hSpCas9	negative selection	1593595
26544153	26544176	1	-	26627737	HeLa	viability after 15 days	GGGCAGATAGGTCTGACACCTGG	RPS6KA1	ENSG00000117676	0.7548650691894438	[136]	[4,129,152]	6	hSpCas9	negative selection	1593596
26546023	26546046	1	-	26627737	HeLa	viability after 15 days	GCACACTCACCGAGTCCCGCTGG	RPS6KA1	ENSG00000117676	0.6648044647508848	[354]	[279,185,219]	5	hSpCas9	negative selection	1593597
26546894	26546917	1	+	26627737	HeLa	viability after 15 days	ATCACGCACCACGTCAAGGCTGG	RPS6KA1	ENSG00000117676	0.6346658106386489	[266]	[236,188,71]	5	hSpCas9	negative selection	1593598
26551404	26551427	1	-	26627737	HeLa	viability after 15 days	TCTCCATCTTGGTCCGGACGCGG	RPS6KA1	ENSG00000117676	0.8135643889136276	[277]	[59,200,348]	6	hSpCas9	negative selection	1593599
26529946	26529969	1	-	26627737	HeLa	viability after 18 days	CACTAGCTCCATGAGCGGCCAGG	RPS6KA1	ENSG00000117676	-0.6184382192782824	[268]	[9,72,114]	-5	hSpCas9	negative selection	1675909
26543207	26543230	1	-	26627737	HeLa	viability after 18 days	CTGCTCACCTTTCTGGGACAGGG	RPS6KA1	ENSG00000117676	0.09041837781144113	[1044]	[243,299,648]	0	hSpCas9	negative selection	1675910
26544153	26544176	1	-	26627737	HeLa	viability after 18 days	GGGCAGATAGGTCTGACACCTGG	RPS6KA1	ENSG00000117676	0.7993324721080801	[136]	[3,113,152]	6	hSpCas9	negative selection	1675911
26546023	26546046	1	-	26627737	HeLa	viability after 18 days	GCACACTCACCGAGTCCCGCTGG	RPS6KA1	ENSG00000117676	0.696561068628675	[354]	[188,164,219]	5	hSpCas9	negative selection	1675912
26546894	26546917	1	+	26627737	HeLa	viability after 18 days	ATCACGCACCACGTCAAGGCTGG	RPS6KA1	ENSG00000117676	0.6195705017141182	[266]	[159,150,71]	5	hSpCas9	negative selection	1675913
26551404	26551427	1	-	26627737	HeLa	viability after 18 days	TCTCCATCTTGGTCCGGACGCGG	RPS6KA1	ENSG00000117676	0.7818804389276144	[277]	[36,159,348]	6	hSpCas9	negative selection	1675914
26529946	26529969	1	-	26627737	HCT116	viability after 6 days	CACTAGCTCCATGAGCGGCCAGG	RPS6KA1	ENSG00000117676	-0.8966459017167323	[431]	[98,1]	-5	hSpCas9	negative selection	1758224
26543207	26543230	1	-	26627737	HCT116	viability after 6 days	CTGCTCACCTTTCTGGGACAGGG	RPS6KA1	ENSG00000117676	-0.01549388589114209	[1121]	[227,144]	0	hSpCas9	negative selection	1758225
26544153	26544176	1	-	26627737	HCT116	viability after 6 days	GGGCAGATAGGTCTGACACCTGG	RPS6KA1	ENSG00000117676	-1.5030690824218431	[110]	[0,8]	-7	hSpCas9	negative selection	1758226
26546023	26546046	1	-	26627737	HCT116	viability after 6 days	GCACACTCACCGAGTCCCGCTGG	RPS6KA1	ENSG00000117676	1.3263155375060447	[941]	[400,354]	7	hSpCas9	negative selection	1758227
26546894	26546917	1	+	26627737	HCT116	viability after 6 days	ATCACGCACCACGTCAAGGCTGG	RPS6KA1	ENSG00000117676	0.948959214056009	[479]	[242,91]	5	hSpCas9	negative selection	1758228
26551404	26551427	1	-	26627737	HCT116	viability after 6 days	TCTCCATCTTGGTCCGGACGCGG	RPS6KA1	ENSG00000117676	1.7792770388663066	[206]	[306,3]	8	hSpCas9	negative selection	1758229
26529946	26529969	1	-	26627737	HCT116	viability after 8 days	CACTAGCTCCATGAGCGGCCAGG	RPS6KA1	ENSG00000117676	-1.0541003333872694	[224]	[58,50,68]	-8	hSpCas9	negative selection	1840539
26543207	26543230	1	-	26627737	HCT116	viability after 8 days	CTGCTCACCTTTCTGGGACAGGG	RPS6KA1	ENSG00000117676	0.5487198715262848	[402]	[289,451,232]	5	hSpCas9	negative selection	1840540
26544153	26544176	1	-	26627737	HCT116	viability after 8 days	GGGCAGATAGGTCTGACACCTGG	RPS6KA1	ENSG00000117676	-0.6844839770658137	[179]	[18,71,92]	-7	hSpCas9	negative selection	1840541
26546023	26546046	1	-	26627737	HCT116	viability after 8 days	GCACACTCACCGAGTCCCGCTGG	RPS6KA1	ENSG00000117676	0.39599649324359965	[119]	[131,56,72]	4	hSpCas9	negative selection	1840542
26546894	26546917	1	+	26627737	HCT116	viability after 8 days	ATCACGCACCACGTCAAGGCTGG	RPS6KA1	ENSG00000117676	-0.5660800650773437	[469]	[147,175,199]	-6	hSpCas9	negative selection	1840543
26551404	26551427	1	-	26627737	HCT116	viability after 8 days	TCTCCATCTTGGTCCGGACGCGG	RPS6KA1	ENSG00000117676	-0.6307882471042684	[290]	[156,81,72]	-6	hSpCas9	negative selection	1840544
26529946	26529969	1	-	26627737	HCT116	viability after 9 days	CACTAGCTCCATGAGCGGCCAGG	RPS6KA1	ENSG00000117676	-1.9825354593881186	[431]	[55,7]	-8	hSpCas9	negative selection	1922854
26543207	26543230	1	-	26627737	HCT116	viability after 9 days	CTGCTCACCTTTCTGGGACAGGG	RPS6KA1	ENSG00000117676	0.4031457484323313	[1121]	[465,340]	3	hSpCas9	negative selection	1922855
26544153	26544176	1	-	26627737	HCT116	viability after 9 days	GGGCAGATAGGTCTGACACCTGG	RPS6KA1	ENSG00000117676	1.4630449140691417	[110]	[31,120]	8	hSpCas9	negative selection	1922856
26546023	26546046	1	-	26627737	HCT116	viability after 9 days	GCACACTCACCGAGTCCCGCTGG	RPS6KA1	ENSG00000117676	-1.0430040734808244	[941]	[149,99]	-6	hSpCas9	negative selection	1922857
26546894	26546917	1	+	26627737	HCT116	viability after 9 days	ATCACGCACCACGTCAAGGCTGG	RPS6KA1	ENSG00000117676	0.2674154695917637	[479]	[227,95]	2	hSpCas9	negative selection	1922858
26551404	26551427	1	-	26627737	HCT116	viability after 9 days	TCTCCATCTTGGTCCGGACGCGG	RPS6KA1	ENSG00000117676	1.8861563950387752	[206]	[248,168]	9	hSpCas9	negative selection	1922859
26529946	26529969	1	-	26627737	HCT116	viability after 12 days	CACTAGCTCCATGAGCGGCCAGG	RPS6KA1	ENSG00000117676	-1.5274339707329334	[224]	[32,50,39]	-9	hSpCas9	negative selection	2005169
26543207	26543230	1	-	26627737	HCT116	viability after 12 days	CTGCTCACCTTTCTGGGACAGGG	RPS6KA1	ENSG00000117676	0.8333847791091484	[402]	[280,517,344]	7	hSpCas9	negative selection	2005170
26544153	26544176	1	-	26627737	HCT116	viability after 12 days	GGGCAGATAGGTCTGACACCTGG	RPS6KA1	ENSG00000117676	-0.5573349700033349	[179]	[22,85,87]	-6	hSpCas9	negative selection	2005171
26546023	26546046	1	-	26627737	HCT116	viability after 12 days	GCACACTCACCGAGTCCCGCTGG	RPS6KA1	ENSG00000117676	1.3647394130753705	[119]	[243,118,115]	9	hSpCas9	negative selection	2005172
26546894	26546917	1	+	26627737	HCT116	viability after 12 days	ATCACGCACCACGTCAAGGCTGG	RPS6KA1	ENSG00000117676	0.09987607666097809	[469]	[174,223,401]	1	hSpCas9	negative selection	2005173
26551404	26551427	1	-	26627737	HCT116	viability after 12 days	TCTCCATCTTGGTCCGGACGCGG	RPS6KA1	ENSG00000117676	-0.6233374342180504	[290]	[97,142,57]	-6	hSpCas9	negative selection	2005174
26529946	26529969	1	-	26627737	HCT116	viability after 15 days	CACTAGCTCCATGAGCGGCCAGG	RPS6KA1	ENSG00000117676	-0.9946893760151546	[224]	[45,60,84]	-7	hSpCas9	negative selection	2087484
26543207	26543230	1	-	26627737	HCT116	viability after 15 days	CTGCTCACCTTTCTGGGACAGGG	RPS6KA1	ENSG00000117676	0.4565753862948174	[402]	[250,400,292]	4	hSpCas9	negative selection	2087485
26544153	26544176	1	-	26627737	HCT116	viability after 15 days	GGGCAGATAGGTCTGACACCTGG	RPS6KA1	ENSG00000117676	-0.8550772484273524	[179]	[16,45,102]	-7	hSpCas9	negative selection	2087486
26546023	26546046	1	-	26627737	HCT116	viability after 15 days	GCACACTCACCGAGTCCCGCTGG	RPS6KA1	ENSG00000117676	0.420329305231107	[119]	[199,14,74]	4	hSpCas9	negative selection	2087487
26546894	26546917	1	+	26627737	HCT116	viability after 15 days	ATCACGCACCACGTCAAGGCTGG	RPS6KA1	ENSG00000117676	-0.23232993583488076	[469]	[211,232,241]	-2	hSpCas9	negative selection	2087488
26551404	26551427	1	-	26627737	HCT116	viability after 15 days	TCTCCATCTTGGTCCGGACGCGG	RPS6KA1	ENSG00000117676	-0.5944927098831332	[290]	[113,153,64]	-6	hSpCas9	negative selection	2087489
26529946	26529969	1	-	26627737	HCT116	viability after 18 days	CACTAGCTCCATGAGCGGCCAGG	RPS6KA1	ENSG00000117676	-1.581280997598721	[224]	[27,5,78]	-8	hSpCas9	negative selection	2169799
26543207	26543230	1	-	26627737	HCT116	viability after 18 days	CTGCTCACCTTTCTGGGACAGGG	RPS6KA1	ENSG00000117676	-0.11275862723586788	[402]	[196,177,164]	-1	hSpCas9	negative selection	2169800
26544153	26544176	1	-	26627737	HCT116	viability after 18 days	GGGCAGATAGGTCTGACACCTGG	RPS6KA1	ENSG00000117676	-0.489871422050289	[179]	[13,37,138]	-4	hSpCas9	negative selection	2169801
26546023	26546046	1	-	26627737	HCT116	viability after 18 days	GCACACTCACCGAGTCCCGCTGG	RPS6KA1	ENSG00000117676	1.4430945849536971	[119]	[195,6,285]	8	hSpCas9	negative selection	2169802
26546894	26546917	1	+	26627737	HCT116	viability after 18 days	ATCACGCACCACGTCAAGGCTGG	RPS6KA1	ENSG00000117676	-0.09236295228975466	[469]	[75,229,337]	-1	hSpCas9	negative selection	2169803
26551404	26551427	1	-	26627737	HCT116	viability after 18 days	TCTCCATCTTGGTCCGGACGCGG	RPS6KA1	ENSG00000117676	-0.6852224287158034	[290]	[128,65,67]	-6	hSpCas9	negative selection	2169804
26546863	26546886	1	+	24336569	HL60	viability	TCAGGATGAGGGCGTCCTCAAGG	RPS6KA1	ENSG00000117676	0.10038192640675492	[1231]	[2794]	1	hSpCas9	negative selection	2292958
26546878	26546901	1	-	24336569	HL60	viability	GCGTGATGGAGATCTCCTTGAGG	RPS6KA1	ENSG00000117676	-1.1208306642163748	[742]	[722]	-7	hSpCas9	negative selection	2292959
26546890	26546913	1	+	24336569	HL60	viability	CTCCATCACGCACCACGTCAAGG	RPS6KA1	ENSG00000117676	-0.3282936346062091	[902]	[1521]	-3	hSpCas9	negative selection	2292960
26546902	26546925	1	-	24336569	HL60	viability	TCTCAGAGCCAGCCTTGACGTGG	RPS6KA1	ENSG00000117676	-0.1650077414119095	[470]	[888]	-1	hSpCas9	negative selection	2292961
26546933	26546956	1	-	24336569	HL60	viability	TTGAGGAGCTCGAAATGGGATGG	RPS6KA1	ENSG00000117676	0.13508851680009937	[777]	[1807]	1	hSpCas9	negative selection	2292962
26546938	26546961	1	-	24336569	HL60	viability	GAACCTTGAGGAGCTCGAAATGG	RPS6KA1	ENSG00000117676	0.7930050172872448	[356]	[1308]	6	hSpCas9	negative selection	2292963
26546947	26546970	1	+	24336569	HL60	viability	GCTCCTCAAGGTTCTGGGCCAGG	RPS6KA1	ENSG00000117676	0.5572863647384476	[350]	[1092]	5	hSpCas9	negative selection	2292964
26546957	26546980	1	+	24336569	HL60	viability	GTTCTGGGCCAGGGATCCTTTGG	RPS6KA1	ENSG00000117676	1.177270167771272	[307]	[1473]	8	hSpCas9	negative selection	2292965
26546965	26546988	1	-	24336569	HL60	viability	TCACTTTGCCAAAGGATCCCTGG	RPS6KA1	ENSG00000117676	0.017711304461939137	[800]	[1715]	0	hSpCas9	negative selection	2292966
26546973	26546996	1	-	24336569	HL60	viability	CTCATGACTCACTTTGCCAAAGG	RPS6KA1	ENSG00000117676	0.36651749726486293	[643]	[1756]	3	hSpCas9	negative selection	2292967
26546863	26546886	1	+	24336569	KBM7	viability	TCAGGATGAGGGCGTCCTCAAGG	RPS6KA1	ENSG00000117676	-0.21465038047859286	[915]	[2152]	-2	hSpCas9	negative selection	2360135
26546878	26546901	1	-	24336569	KBM7	viability	GCGTGATGGAGATCTCCTTGAGG	RPS6KA1	ENSG00000117676	-0.5967782171172298	[513]	[926]	-5	hSpCas9	negative selection	2360136
26546890	26546913	1	+	24336569	KBM7	viability	CTCCATCACGCACCACGTCAAGG	RPS6KA1	ENSG00000117676	0.8729452708164849	[616]	[3081]	7	hSpCas9	negative selection	2360137
26546902	26546925	1	-	24336569	KBM7	viability	TCTCAGAGCCAGCCTTGACGTGG	RPS6KA1	ENSG00000117676	-0.5197912600470984	[296]	[564]	-4	hSpCas9	negative selection	2360138
26546933	26546956	1	-	24336569	KBM7	viability	TTGAGGAGCTCGAAATGGGATGG	RPS6KA1	ENSG00000117676	0.26970478813861537	[523]	[1722]	2	hSpCas9	negative selection	2360139
26546938	26546961	1	-	24336569	KBM7	viability	GAACCTTGAGGAGCTCGAAATGG	RPS6KA1	ENSG00000117676	-0.5297118238383518	[514]	[972]	-4	hSpCas9	negative selection	2360140
26546947	26546970	1	+	24336569	KBM7	viability	GCTCCTCAAGGTTCTGGGCCAGG	RPS6KA1	ENSG00000117676	0.9213268396198255	[283]	[1466]	7	hSpCas9	negative selection	2360141
26546957	26546980	1	+	24336569	KBM7	viability	GTTCTGGGCCAGGGATCCTTTGG	RPS6KA1	ENSG00000117676	0.7090642837880768	[387]	[1729]	6	hSpCas9	negative selection	2360142
26546965	26546988	1	-	24336569	KBM7	viability	TCACTTTGCCAAAGGATCCCTGG	RPS6KA1	ENSG00000117676	0.24949367049381094	[494]	[1604]	2	hSpCas9	negative selection	2360143
26546973	26546996	1	-	24336569	KBM7	viability	CTCATGACTCACTTTGCCAAAGG	RPS6KA1	ENSG00000117676	1.4709226894299245	[329]	[2494]	9	hSpCas9	negative selection	2360144
26545726	26545749	1	+	25494202	A375	resistance to PLX-4720 (puromycin)	ACGTGGTGAGGGTGTAGGCCTGG	RPS6KA1	ENSG00000117676	0.9420140257574894	[99,68]	[2,69]	4	dCas9-VP64	positive selection	2388014
26545726	26545749	CHR_HG2058_PATCH	+	25494202	A375	resistance to PLX-4720 (puromycin)	ACGTGGTGAGGGTGTAGGCCTGG	RPS6KA1	ENSG00000281877	0.9420140257574894	[99,68]	[2,69]	4	dCas9-VP64	positive selection	2388015
26545680	26545703	1	+	25494202	A375	resistance to PLX-4720 (puromycin)	AGGGCAGCCCTCAGGCTCTGAGG	RPS6KA1	ENSG00000117676	0.32118399264726416	[13,41]	[4,9]	1	dCas9-VP64	positive selection	2388016
26545680	26545703	CHR_HG2058_PATCH	+	25494202	A375	resistance to PLX-4720 (puromycin)	AGGGCAGCCCTCAGGCTCTGAGG	RPS6KA1	ENSG00000281877	0.32118399264726416	[13,41]	[4,9]	1	dCas9-VP64	positive selection	2388017
26545744	26545767	CHR_HG2058_PATCH	-	25494202	A375	resistance to PLX-4720 (puromycin)	GCCTGTGGTTTCCCAGCACCAGG	RPS6KA1	ENSG00000281877	-0.17768848041268104	[387,405]	[46,109]	0	dCas9-VP64	positive selection	2388018
26545744	26545767	1	-	25494202	A375	resistance to PLX-4720 (puromycin)	GCCTGTGGTTTCCCAGCACCAGG	RPS6KA1	ENSG00000117676	-0.17768848041268104	[387,405]	[46,109]	0	dCas9-VP64	positive selection	2388019
26573846	26573869	1	+	25494202	A375	resistance to PLX-4720 (puromycin)	GAGAATCGCTTGAACCCTGGGGG	RPS6KA1	ENSG00000117676	-0.5583774166941213	[49,17]	[4,3]	-3	dCas9-VP64	positive selection	2470296
26573846	26573869	CHR_HG2058_PATCH	+	25494202	A375	resistance to PLX-4720 (puromycin)	GAGAATCGCTTGAACCCTGGGGG	RPS6KA1	ENSG00000281877	-0.5583774166941213	[49,17]	[4,3]	-3	dCas9-VP64	positive selection	2470297
26545726	26545749	1	+	25494202	A375	resistance to PLX-4720 (zeocin)	ACGTGGTGAGGGTGTAGGCCTGG	RPS6KA1	ENSG00000117676	-0.8066384836784739	[472,69]	[91,12]	-7	dCas9-VP64	positive selection	2483269
26545726	26545749	CHR_HG2058_PATCH	+	25494202	A375	resistance to PLX-4720 (zeocin)	ACGTGGTGAGGGTGTAGGCCTGG	RPS6KA1	ENSG00000281877	-0.8066384836784739	[472,69]	[91,12]	-7	dCas9-VP64	positive selection	2483270
26545680	26545703	1	+	25494202	A375	resistance to PLX-4720 (zeocin)	AGGGCAGCCCTCAGGCTCTGAGG	RPS6KA1	ENSG00000117676	-0.19941171735615293	[75,36]	[23,7]	-2	dCas9-VP64	positive selection	2483271
26545680	26545703	CHR_HG2058_PATCH	+	25494202	A375	resistance to PLX-4720 (zeocin)	AGGGCAGCCCTCAGGCTCTGAGG	RPS6KA1	ENSG00000281877	-0.19941171735615293	[75,36]	[23,7]	-2	dCas9-VP64	positive selection	2483272
26545744	26545767	CHR_HG2058_PATCH	-	25494202	A375	resistance to PLX-4720 (zeocin)	GCCTGTGGTTTCCCAGCACCAGG	RPS6KA1	ENSG00000281877	0.708672616513528	[78,104]	[84,14]	5	dCas9-VP64	positive selection	2483273
26545744	26545767	1	-	25494202	A375	resistance to PLX-4720 (zeocin)	GCCTGTGGTTTCCCAGCACCAGG	RPS6KA1	ENSG00000117676	0.708672616513528	[78,104]	[84,14]	5	dCas9-VP64	positive selection	2483274
26573846	26573869	1	+	25494202	A375	resistance to PLX-4720 (zeocin)	GAGAATCGCTTGAACCCTGGGGG	RPS6KA1	ENSG00000117676	-1.4985881155418108	[182,12]	[19,2]	-9	dCas9-VP64	positive selection	2565551
26573846	26573869	CHR_HG2058_PATCH	+	25494202	A375	resistance to PLX-4720 (zeocin)	GAGAATCGCTTGAACCCTGGGGG	RPS6KA1	ENSG00000281877	-1.4985881155418108	[182,12]	[19,2]	-9	dCas9-VP64	positive selection	2565552
26529973	26529996	1	+	27013184	SW480	treatment with recombinant TRAIL	TGGACCCGGAGGTGAGTGAGCGG	RPS6KA1	ENSG00000117676	-0.5388383315282738	[137,83]	[43,18]	-2	hSpCas9	positive selection	2958352
26529973	26529996	CHR_HG2058_PATCH	+	27013184	SW480	treatment with recombinant TRAIL	TGGACCCGGAGGTGAGTGAGCGG	RPS6KA1	ENSG00000281877	-0.5388383315282738	[137,83]	[43,18]	-2	hSpCas9	positive selection	2958353
26546890	26546913	1	+	27013184	SW480	treatment with recombinant TRAIL	CTCCATCACGCACCACGTCAAGG	RPS6KA1	ENSG00000117676	0.19441020088385164	[164,321]	[103,134]	1	hSpCas9	positive selection	2958354
26546890	26546913	CHR_HG2058_PATCH	+	27013184	SW480	treatment with recombinant TRAIL	CTCCATCACGCACCACGTCAAGG	RPS6KA1	ENSG00000281877	0.19441020088385164	[164,321]	[103,134]	1	hSpCas9	positive selection	2958355
26546894	26546917	CHR_HG2058_PATCH	+	27013184	SW480	treatment with recombinant TRAIL	ATCACGCACCACGTCAAGGCTGG	RPS6KA1	ENSG00000281877	0.44659406514292677	[31,36]	[1,45]	2	hSpCas9	positive selection	2958356
26546894	26546917	1	+	27013184	SW480	treatment with recombinant TRAIL	ATCACGCACCACGTCAAGGCTGG	RPS6KA1	ENSG00000117676	0.44659406514292677	[31,36]	[1,45]	2	hSpCas9	positive selection	2958357
26546905	26546928	1	+	27013184	SW480	treatment with recombinant TRAIL	CGTCAAGGCTGGCTCTGAGAAGG	RPS6KA1	ENSG00000117676	-0.6073189059745234	[264,593]	[93,150]	-3	hSpCas9	positive selection	2958358
26546905	26546928	CHR_HG2058_PATCH	+	27013184	SW480	treatment with recombinant TRAIL	CGTCAAGGCTGGCTCTGAGAAGG	RPS6KA1	ENSG00000281877	-0.6073189059745234	[264,593]	[93,150]	-3	hSpCas9	positive selection	2958359
26551440	26551463	CHR_HG2058_PATCH	+	27013184	SW480	treatment with recombinant TRAIL	TGATGTAAATCACCCATTCGTGG	RPS6KA1	ENSG00000281877	0.3905154726100356	[72,112]	[70,23]	2	hSpCas9	positive selection	2958360
26551440	26551463	1	+	27013184	SW480	treatment with recombinant TRAIL	TGATGTAAATCACCCATTCGTGG	RPS6KA1	ENSG00000117676	0.3905154726100356	[72,112]	[70,23]	2	hSpCas9	positive selection	2958361
26546947	26546970	1	+	27013184	SW480	treatment with recombinant TRAIL	GCTCCTCAAGGTTCTGGGCCAGG	RPS6KA1	ENSG00000117676	-0.40120193106106605	[523,367]	[199,73]	-2	hSpCas9	positive selection	2958362
26546947	26546970	CHR_HG2058_PATCH	+	27013184	SW480	treatment with recombinant TRAIL	GCTCCTCAAGGTTCTGGGCCAGG	RPS6KA1	ENSG00000281877	-0.40120193106106605	[523,367]	[199,73]	-2	hSpCas9	positive selection	2958363
26546948	26546971	1	+	27013184	SW480	treatment with recombinant TRAIL	CTCCTCAAGGTTCTGGGCCAGGG	RPS6KA1	ENSG00000117676	-0.9391780241800474	[665,711]	[121,200]	-4	hSpCas9	positive selection	2958364
26546948	26546971	CHR_HG2058_PATCH	+	27013184	SW480	treatment with recombinant TRAIL	CTCCTCAAGGTTCTGGGCCAGGG	RPS6KA1	ENSG00000281877	-0.9391780241800474	[665,711]	[121,200]	-4	hSpCas9	positive selection	2958365
26547205	26547228	1	+	27013184	SW480	treatment with recombinant TRAIL	AAGTCACCCGGCCTGACAGTGGG	RPS6KA1	ENSG00000117676	3.2777205517863828	[40,32]	[216,69]	9	hSpCas9	positive selection	2958366
26547205	26547228	CHR_HG2058_PATCH	+	27013184	SW480	treatment with recombinant TRAIL	AAGTCACCCGGCCTGACAGTGGG	RPS6KA1	ENSG00000281877	3.2777205517863828	[40,32]	[216,69]	9	hSpCas9	positive selection	2958367
26547224	26547247	CHR_HG2058_PATCH	+	27013184	SW480	treatment with recombinant TRAIL	TGGGCACCTGTATGCTATGAAGG	RPS6KA1	ENSG00000281877	0.896916040177042	[418,604]	[268,597]	4	hSpCas9	positive selection	2958368
26547224	26547247	1	+	27013184	SW480	treatment with recombinant TRAIL	TGGGCACCTGTATGCTATGAAGG	RPS6KA1	ENSG00000117676	0.896916040177042	[418,604]	[268,597]	4	hSpCas9	positive selection	2958369
26547256	26547279	1	+	27013184	SW480	treatment with recombinant TRAIL	AGGCAACGCTGAAAGGTGAGTGG	RPS6KA1	ENSG00000117676	4.228847897509494	[1,3]	[11,39]	9	hSpCas9	positive selection	2958370
26547256	26547279	CHR_HG2058_PATCH	+	27013184	SW480	treatment with recombinant TRAIL	AGGCAACGCTGAAAGGTGAGTGG	RPS6KA1	ENSG00000281877	4.228847897509494	[1,3]	[11,39]	9	hSpCas9	positive selection	2958371
26547257	26547280	CHR_HG2058_PATCH	+	27013184	SW480	treatment with recombinant TRAIL	GGCAACGCTGAAAGGTGAGTGGG	RPS6KA1	ENSG00000281877	1.5328998057051808	[55,26]	[45,63]	7	hSpCas9	positive selection	2958372
26547257	26547280	1	+	27013184	SW480	treatment with recombinant TRAIL	GGCAACGCTGAAAGGTGAGTGGG	RPS6KA1	ENSG00000117676	1.5328998057051808	[55,26]	[45,63]	7	hSpCas9	positive selection	2958373
26529920	26529943	CHR_HG2058_PATCH	+	27013184	SW480	treatment with recombinant TRAIL	GATGCCGCTCGCCCAGCTCAAGG	RPS6KA1	ENSG00000281877	0.6688897339744737	[493,765]	[295,605]	3	hSpCas9	positive selection	2958374
26529920	26529943	1	+	27013184	SW480	treatment with recombinant TRAIL	GATGCCGCTCGCCCAGCTCAAGG	RPS6KA1	ENSG00000117676	0.6688897339744737	[493,765]	[295,605]	3	hSpCas9	positive selection	2958375
26551456	26551479	1	+	27013184	SW480	treatment with recombinant TRAIL	TTCGTGGTGAAGCTGCACTATGG	RPS6KA1	ENSG00000117676	0.5426024115471685	[211,209]	[116,154]	2	hSpCas9	positive selection	2958376
26551456	26551479	CHR_HG2058_PATCH	+	27013184	SW480	treatment with recombinant TRAIL	TTCGTGGTGAAGCTGCACTATGG	RPS6KA1	ENSG00000281877	0.5426024115471685	[211,209]	[116,154]	2	hSpCas9	positive selection	2958377
26547258	26547281	1	+	27013184	SW480	treatment with recombinant TRAIL	GCAACGCTGAAAGGTGAGTGGGG	RPS6KA1	ENSG00000117676	1.8981089130839794	[189,179]	[230,393]	8	hSpCas9	positive selection	2958378
26547258	26547281	CHR_HG2058_PATCH	+	27013184	SW480	treatment with recombinant TRAIL	GCAACGCTGAAAGGTGAGTGGGG	RPS6KA1	ENSG00000281877	1.8981089130839794	[189,179]	[230,393]	8	hSpCas9	positive selection	2958379
26551434	26551457	CHR_HG2058_PATCH	-	27013184	SW480	treatment with recombinant TRAIL	ATGGGTGATTTACATCAGCCAGG	RPS6KA1	ENSG00000281877	0.6159825017374486	[360,260]	[220,190]	3	hSpCas9	positive selection	2958380
26551434	26551457	1	-	27013184	SW480	treatment with recombinant TRAIL	ATGGGTGATTTACATCAGCCAGG	RPS6KA1	ENSG00000117676	0.6159825017374486	[360,260]	[220,190]	3	hSpCas9	positive selection	2958381
26551452	26551475	CHR_HG2058_PATCH	-	27013184	SW480	treatment with recombinant TRAIL	AGTGCAGCTTCACCACGAATGGG	RPS6KA1	ENSG00000281877	-0.36488602440240586	[117,243]	[26,103]	-2	hSpCas9	positive selection	2958382
26551452	26551475	1	-	27013184	SW480	treatment with recombinant TRAIL	AGTGCAGCTTCACCACGAATGGG	RPS6KA1	ENSG00000117676	-0.36488602440240586	[117,243]	[26,103]	-2	hSpCas9	positive selection	2958383
26551453	26551476	1	-	27013184	SW480	treatment with recombinant TRAIL	TAGTGCAGCTTCACCACGAATGG	RPS6KA1	ENSG00000117676	0.3035609984951451	[176,166]	[83,102]	1	hSpCas9	positive selection	2958384
26551453	26551476	CHR_HG2058_PATCH	-	27013184	SW480	treatment with recombinant TRAIL	TAGTGCAGCTTCACCACGAATGG	RPS6KA1	ENSG00000281877	0.3035609984951451	[176,166]	[83,102]	1	hSpCas9	positive selection	2958385
26529928	26529951	CHR_HG2058_PATCH	+	27013184	SW480	treatment with recombinant TRAIL	TCGCCCAGCTCAAGGAGCCCTGG	RPS6KA1	ENSG00000281877	-0.550504972435991	[1325,2061]	[297,761]	-2	hSpCas9	positive selection	2958386
26529928	26529951	1	+	27013184	SW480	treatment with recombinant TRAIL	TCGCCCAGCTCAAGGAGCCCTGG	RPS6KA1	ENSG00000117676	-0.550504972435991	[1325,2061]	[297,761]	-2	hSpCas9	positive selection	2958387
26551468	26551491	CHR_HG2058_PATCH	+	27013184	SW480	treatment with recombinant TRAIL	CTGCACTATGGTAAAGCTTCTGG	RPS6KA1	ENSG00000281877	0.9149969907921447	[177,198]	[164,134]	4	hSpCas9	positive selection	2958388
26551468	26551491	1	+	27013184	SW480	treatment with recombinant TRAIL	CTGCACTATGGTAAAGCTTCTGG	RPS6KA1	ENSG00000117676	0.9149969907921447	[177,198]	[164,134]	4	hSpCas9	positive selection	2958389
26529938	26529961	1	+	27013184	SW480	treatment with recombinant TRAIL	CAAGGAGCCCTGGCCGCTCATGG	RPS6KA1	ENSG00000117676	1.271165371527494	[170,211]	[107,324]	6	hSpCas9	positive selection	2958390
26529938	26529961	CHR_HG2058_PATCH	+	27013184	SW480	treatment with recombinant TRAIL	CAAGGAGCCCTGGCCGCTCATGG	RPS6KA1	ENSG00000281877	1.271165371527494	[170,211]	[107,324]	6	hSpCas9	positive selection	2958391
26546878	26546901	CHR_HG2058_PATCH	-	27013184	SW480	treatment with recombinant TRAIL	GCGTGATGGAGATCTCCTTGAGG	RPS6KA1	ENSG00000281877	1.3502482266676834	[109,91]	[59,185]	6	hSpCas9	positive selection	2958392
26546878	26546901	1	-	27013184	SW480	treatment with recombinant TRAIL	GCGTGATGGAGATCTCCTTGAGG	RPS6KA1	ENSG00000117676	1.3502482266676834	[109,91]	[59,185]	6	hSpCas9	positive selection	2958393
26546892	26546915	CHR_HG2058_PATCH	-	27013184	SW480	treatment with recombinant TRAIL	AGCCTTGACGTGGTGCGTGATGG	RPS6KA1	ENSG00000281877	2.855022283138553	[192,420]	[1020,792]	9	hSpCas9	positive selection	2958394
26546892	26546915	1	-	27013184	SW480	treatment with recombinant TRAIL	AGCCTTGACGTGGTGCGTGATGG	RPS6KA1	ENSG00000117676	2.855022283138553	[192,420]	[1020,792]	9	hSpCas9	positive selection	2958395
26546902	26546925	CHR_HG2058_PATCH	-	27013184	SW480	treatment with recombinant TRAIL	TCTCAGAGCCAGCCTTGACGTGG	RPS6KA1	ENSG00000281877	-0.1461529228658216	[526,843]	[312,188]	0	hSpCas9	positive selection	2958396
26546902	26546925	1	-	27013184	SW480	treatment with recombinant TRAIL	TCTCAGAGCCAGCCTTGACGTGG	RPS6KA1	ENSG00000117676	-0.1461529228658216	[526,843]	[312,188]	0	hSpCas9	positive selection	2958397
26546950	26546973	1	-	27013184	SW480	treatment with recombinant TRAIL	ATCCCTGGCCCAGAACCTTGAGG	RPS6KA1	ENSG00000117676	1.5983005688971856	[663,907]	[848,1245]	7	hSpCas9	positive selection	2958398
26546950	26546973	CHR_HG2058_PATCH	-	27013184	SW480	treatment with recombinant TRAIL	ATCCCTGGCCCAGAACCTTGAGG	RPS6KA1	ENSG00000281877	1.5983005688971856	[663,907]	[848,1245]	7	hSpCas9	positive selection	2958399
26529953	26529976	CHR_HG2058_PATCH	+	27013184	SW480	treatment with recombinant TRAIL	GCTCATGGAGCTAGTGCCTCTGG	RPS6KA1	ENSG00000281877	-1.880151344598873	[673,630]	[98,44]	-7	hSpCas9	positive selection	2958400
26529953	26529976	1	+	27013184	SW480	treatment with recombinant TRAIL	GCTCATGGAGCTAGTGCCTCTGG	RPS6KA1	ENSG00000117676	-1.880151344598873	[673,630]	[98,44]	-7	hSpCas9	positive selection	2958401
26546965	26546988	CHR_HG2058_PATCH	-	27013184	SW480	treatment with recombinant TRAIL	TCACTTTGCCAAAGGATCCCTGG	RPS6KA1	ENSG00000281877	-0.46361751741700363	[87,192]	[25,65]	-2	hSpCas9	positive selection	2958402
26546965	26546988	1	-	27013184	SW480	treatment with recombinant TRAIL	TCACTTTGCCAAAGGATCCCTGG	RPS6KA1	ENSG00000117676	-0.46361751741700363	[87,192]	[25,65]	-2	hSpCas9	positive selection	2958403
26546973	26546996	1	-	27013184	SW480	treatment with recombinant TRAIL	CTCATGACTCACTTTGCCAAAGG	RPS6KA1	ENSG00000117676	1.1817717958679421	[34,8]	[13,34]	5	hSpCas9	positive selection	2958404
26546973	26546996	CHR_HG2058_PATCH	-	27013184	SW480	treatment with recombinant TRAIL	CTCATGACTCACTTTGCCAAAGG	RPS6KA1	ENSG00000281877	1.1817717958679421	[34,8]	[13,34]	5	hSpCas9	positive selection	2958405
26547230	26547253	CHR_HG2058_PATCH	-	27013184	SW480	treatment with recombinant TRAIL	TCAGCACCTTCATAGCATACAGG	RPS6KA1	ENSG00000281877	0.9352787948051258	[251,123]	[184,123]	4	hSpCas9	positive selection	2958406
26547230	26547253	1	-	27013184	SW480	treatment with recombinant TRAIL	TCAGCACCTTCATAGCATACAGG	RPS6KA1	ENSG00000117676	0.9352787948051258	[251,123]	[184,123]	4	hSpCas9	positive selection	2958407
26529959	26529982	CHR_HG2058_PATCH	+	27013184	SW480	treatment with recombinant TRAIL	GGAGCTAGTGCCTCTGGACCCGG	RPS6KA1	ENSG00000281877	-0.6404812699790383	[447,412]	[112,128]	-3	hSpCas9	positive selection	2958408
26529959	26529982	1	+	27013184	SW480	treatment with recombinant TRAIL	GGAGCTAGTGCCTCTGGACCCGG	RPS6KA1	ENSG00000117676	-0.6404812699790383	[447,412]	[112,128]	-3	hSpCas9	positive selection	2958409
26529962	26529985	CHR_HG2058_PATCH	+	27013184	SW480	treatment with recombinant TRAIL	GCTAGTGCCTCTGGACCCGGAGG	RPS6KA1	ENSG00000281877	1.7648342369049836	[227,544]	[605,460]	7	hSpCas9	positive selection	2958410
26529962	26529985	1	+	27013184	SW480	treatment with recombinant TRAIL	GCTAGTGCCTCTGGACCCGGAGG	RPS6KA1	ENSG00000117676	1.7648342369049836	[227,544]	[605,460]	7	hSpCas9	positive selection	2958411
26551653	26551676	1	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	AATGAGATAGAGCTTGCCCTCGG	RPS6KA1	ENSG00000117676	0.14061637916055997	[4,5]	[6,3]	3	hSpCas9	positive selection	3017970
26557006	26557029	1	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	AGGGTGGCTTGATCTCACGACGG	RPS6KA1	ENSG00000117676	0.180564232146734	[3,4]	[2,4]	4	hSpCas9	positive selection	3017971
26555600	26555623	1	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TCAAGCGGAATCCTGCCAACCGG	RPS6KA1	ENSG00000117676	-0.06439781318569363	[2,3]	[2,2]	-1	hSpCas9	positive selection	3017972
26553385	26553408	1	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TTTGCAGGTGATGTTCACGGAGG	RPS6KA1	ENSG00000117676	-0.25287481840185927	[2,3]	[2,1]	-4	hSpCas9	positive selection	3017973
26551653	26551676	1	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	AATGAGATAGAGCTTGCCCTCGG	RPS6KA1	ENSG00000117676	0.312720272941447	[4,4]	[4,3]	5	hSpCas9	positive selection	3085828
26557006	26557029	1	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	AGGGTGGCTTGATCTCACGACGG	RPS6KA1	ENSG00000117676	-0.09388869289733398	[3,3]	[3,1]	-1	hSpCas9	positive selection	3085829
26555600	26555623	1	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TCAAGCGGAATCCTGCCAACCGG	RPS6KA1	ENSG00000117676	0.005334942145720306	[2,2]	[2,0]	0	hSpCas9	positive selection	3085830
26553385	26553408	1	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TTTGCAGGTGATGTTCACGGAGG	RPS6KA1	ENSG00000117676	0.7074293660960771	[2,2]	[5,2]	9	hSpCas9	positive selection	3085831
26553453	26553476		-	24336571	A375	resistance to PLX after 7 days	AAATGATACCCAGGCTGTGCAGG	RPS6KA1	ENSG00000117676	0.15255541382000642	[18,14]	[19,17]	5	hSpCas9	positive selection	3141880
26536935	26536958		-	24336571	A375	resistance to PLX after 7 days	AAGTCCAGCTTCTTCCCCTGAGG	RPS6KA1	ENSG00000117676	0.04173972794892056	[23,20]	[20,23]	1	hSpCas9	positive selection	3141881
26551653	26551676		-	24336571	A375	resistance to PLX after 7 days	AATGAGATAGAGCTTGCCCTCGG	RPS6KA1	ENSG00000117676	0.12019082400087333	[31,27]	[32,30]	4	hSpCas9	positive selection	3141882
26536948	26536971		+	24336571	A375	resistance to PLX after 7 days	AGCTGGACTTCAGCCGTCCAAGG	RPS6KA1	ENSG00000117676	0.23857775120013974	[12,15]	[16,16]	7	hSpCas9	positive selection	3141883
26553444	26553467		+	24336571	A375	resistance to PLX after 7 days	CCTGGATCACCTGCACAGCCTGG	RPS6KA1	ENSG00000117676	0.6023619072061607	[7,6]	[9,13]	9	hSpCas9	positive selection	3141884
26551670	26551693		+	24336571	A375	resistance to PLX after 7 days	CTCATTCTGGACTTCCTGCGTGG	RPS6KA1	ENSG00000117676	0.03198112423523547	[25,31]	[30,28]	1	hSpCas9	positive selection	3141885
26553405	26553428		+	24336571	A375	resistance to PLX after 7 days	GGAGGATGTGAAGTTTTACCTGG	RPS6KA1	ENSG00000117676	0.37837858024437565	[5,4]	[7,6]	8	hSpCas9	positive selection	3141886
26551684	26551707		-	24336571	A375	resistance to PLX after 7 days	TGAAGAGGTCCCCACCACGCAGG	RPS6KA1	ENSG00000117676	0.022421439692986933	[29,23]	[26,28]	0	hSpCas9	positive selection	3141887
26536919	26536942		+	24336571	A375	resistance to PLX after 7 days	TTCCAGAATGGACAGACCTCAGG	RPS6KA1	ENSG00000117676	0.33227944253044606	[22,21]	[26,28]	8	hSpCas9	positive selection	3141888
26553453	26553476		-	24336571	A375	resistance to PLX after 14 days	AAATGATACCCAGGCTGTGCAGG	RPS6KA1	ENSG00000117676	1.1410194540919898	[16,15]	[14,18]	8	hSpCas9	positive selection	3199673
26536935	26536958		-	24336571	A375	resistance to PLX after 14 days	AAGTCCAGCTTCTTCCCCTGAGG	RPS6KA1	ENSG00000117676	-1.0188730130642674	[23,25]	[5,4]	-9	hSpCas9	positive selection	3199674
26551653	26551676		-	24336571	A375	resistance to PLX after 14 days	AATGAGATAGAGCTTGCCCTCGG	RPS6KA1	ENSG00000117676	-0.1630325021426342	[29,16]	[9,8]	-2	hSpCas9	positive selection	3199675
26536948	26536971		+	24336571	A375	resistance to PLX after 14 days	AGCTGGACTTCAGCCGTCCAAGG	RPS6KA1	ENSG00000117676	-0.0149459583329824	[8,22]	[7,5]	0	hSpCas9	positive selection	3199676
26553444	26553467		+	24336571	A375	resistance to PLX after 14 days	CCTGGATCACCTGCACAGCCTGG	RPS6KA1	ENSG00000117676	-0.04927406139078197	[12,9]	[4,4]	0	hSpCas9	positive selection	3199677
26551670	26551693		+	24336571	A375	resistance to PLX after 14 days	CTCATTCTGGACTTCCTGCGTGG	RPS6KA1	ENSG00000117676	0.20807696525413166	[24,30]	[14,13]	2	hSpCas9	positive selection	3199678
26553405	26553428		+	24336571	A375	resistance to PLX after 14 days	GGAGGATGTGAAGTTTTACCTGG	RPS6KA1	ENSG00000117676	0.8809593635860561	[4,4]	[3,4]	7	hSpCas9	positive selection	3199679
26551684	26551707		-	24336571	A375	resistance to PLX after 14 days	TGAAGAGGTCCCCACCACGCAGG	RPS6KA1	ENSG00000117676	1.092040928991593	[22,20]	[23,19]	8	hSpCas9	positive selection	3199680
26536919	26536942		+	24336571	A375	resistance to PLX after 14 days	TTCCAGAATGGACAGACCTCAGG	RPS6KA1	ENSG00000117676	-0.4406640232923107	[34,21]	[7,10]	-5	hSpCas9	positive selection	3199681
26553453	26553476		-	24336571	A375	viability after 7 days	AAATGATACCCAGGCTGTGCAGG	RPS6KA1	ENSG00000117676	0.46503068282297594	[12]	[18,14]	7	hSpCas9	negative selection	3257466
26536935	26536958		-	24336571	A375	viability after 7 days	AAGTCCAGCTTCTTCCCCTGAGG	RPS6KA1	ENSG00000117676	0.019000904562819554	[22]	[23,20]	0	hSpCas9	negative selection	3257467
26551653	26551676		-	24336571	A375	viability after 7 days	AATGAGATAGAGCTTGCCCTCGG	RPS6KA1	ENSG00000117676	-0.09024031096384966	[32]	[31,27]	-1	hSpCas9	negative selection	3257468
26536948	26536971		+	24336571	A375	viability after 7 days	AGCTGGACTTCAGCCGTCCAAGG	RPS6KA1	ENSG00000117676	0.7284364489510939	[8]	[12,15]	9	hSpCas9	negative selection	3257469
26553444	26553467		+	24336571	A375	viability after 7 days	CCTGGATCACCTGCACAGCCTGG	RPS6KA1	ENSG00000117676	-0.11621365730321698	[8]	[7,6]	-2	hSpCas9	negative selection	3257470
26551670	26551693		+	24336571	A375	viability after 7 days	CTCATTCTGGACTTCCTGCGTGG	RPS6KA1	ENSG00000117676	0.236062129085576	[25]	[25,31]	3	hSpCas9	negative selection	3257471
26553405	26553428		+	24336571	A375	viability after 7 days	GGAGGATGTGAAGTTTTACCTGG	RPS6KA1	ENSG00000117676	0.08737235523529963	[4]	[5,4]	1	hSpCas9	negative selection	3257472
26551684	26551707		-	24336571	A375	viability after 7 days	TGAAGAGGTCCCCACCACGCAGG	RPS6KA1	ENSG00000117676	0.042947623207579166	[27]	[29,23]	0	hSpCas9	negative selection	3257473
26536919	26536942		+	24336571	A375	viability after 7 days	TTCCAGAATGGACAGACCTCAGG	RPS6KA1	ENSG00000117676	0.6845937898994	[13]	[22,21]	8	hSpCas9	negative selection	3257474
26553453	26553476		-	24336571	A375	viability after 14 days	AAATGATACCCAGGCTGTGCAGG	RPS6KA1	ENSG00000117676	0.4616389529107961	[12]	[16,15]	6	hSpCas9	negative selection	3315259
26536935	26536958		-	24336571	A375	viability after 14 days	AAGTCCAGCTTCTTCCCCTGAGG	RPS6KA1	ENSG00000117676	0.19246735767278567	[22]	[23,25]	2	hSpCas9	negative selection	3315260
26551653	26551676		-	24336571	A375	viability after 14 days	AATGAGATAGAGCTTGCCCTCGG	RPS6KA1	ENSG00000117676	-0.3956513938695858	[32]	[29,16]	-5	hSpCas9	negative selection	3315261
26536948	26536971		+	24336571	A375	viability after 14 days	AGCTGGACTTCAGCCGTCCAAGG	RPS6KA1	ENSG00000117676	0.9070557527200375	[8]	[8,22]	9	hSpCas9	negative selection	3315262
26553444	26553467		+	24336571	A375	viability after 14 days	CCTGGATCACCTGCACAGCCTGG	RPS6KA1	ENSG00000117676	0.3832458601151254	[8]	[12,9]	5	hSpCas9	negative selection	3315263
26551670	26551693		+	24336571	A375	viability after 14 days	CTCATTCTGGACTTCCTGCGTGG	RPS6KA1	ENSG00000117676	0.1877593417994563	[25]	[24,30]	2	hSpCas9	negative selection	3315264
26553405	26553428		+	24336571	A375	viability after 14 days	GGAGGATGTGAAGTTTTACCTGG	RPS6KA1	ENSG00000117676	-0.021195939320881374	[4]	[4,4]	0	hSpCas9	negative selection	3315265
26551684	26551707		-	24336571	A375	viability after 14 days	TGAAGAGGTCCCCACCACGCAGG	RPS6KA1	ENSG00000117676	-0.2475899846723577	[27]	[22,20]	-3	hSpCas9	negative selection	3315266
26536919	26536942		+	24336571	A375	viability after 14 days	TTCCAGAATGGACAGACCTCAGG	RPS6KA1	ENSG00000117676	1.064898289639782	[13]	[34,21]	9	hSpCas9	negative selection	3315267
26536919	26536942	1	+	27383988	293T	resistance to West Nile virus (flavivirus)	TTCCAGAATGGACAGACCTCAGG	RPS6KA1	ENSG00000117676	-0.6253168379160062	[235,235]	[0,0]	-4	hSpCas9	positive selection	3390664
26553453	26553476	1	-	27383988	293T	resistance to West Nile virus (flavivirus)	AAATGATACCCAGGCTGTGCAGG	RPS6KA1	ENSG00000117676	0.4499712893882311	[111,111]	[0,0]	2	hSpCas9	positive selection	3390665
26553483	26553506	1	-	27383988	293T	resistance to West Nile virus (flavivirus)	TCACTCACTTCTCAGGCTTGAGG	RPS6KA1	ENSG00000117676	-1.3201026165899135	[381,381]	[0,0]	-8	hSpCas9	positive selection	3390666
26551653	26551676	1	-	26780180	HT29	viability (Avana library 4 designs)	AATGAGATAGAGCTTGCCCTCGG	RPS6KA1	ENSG00000117676	0.643832488617485	[]	[]	2	hSpCas9	negative selection	3456351
26557006	26557029	1	-	26780180	HT29	viability (Avana library 4 designs)	AGGGTGGCTTGATCTCACGACGG	RPS6KA1	ENSG00000117676	1.33231561318445	[]	[]	5	hSpCas9	negative selection	3456352
26555599	26555622	1	+	26780180	HT29	viability (Avana library 4 designs)	TCAAGCGGAATCCTGCCAACCGG	RPS6KA1	ENSG00000117676	0.590205349591389	[]	[]	2	hSpCas9	negative selection	3456353
26553384	26553407	1	+	26780180	HT29	viability (Avana library 4 designs)	TTTGCAGGTGATGTTCACGGAGG	RPS6KA1	ENSG00000117676	0.107418056645131	[]	[]	0	hSpCas9	negative selection	3456354
26553384	26553407	1	+	26780180	A375	viability (Avana lentiCRISPRv2)	TTTGCAGGTGATGTTCACGGAGG	RPS6KA1	ENSG00000117676	2.72503560159247	[]	[]	4	hSpCas9	negative selection	3554786
26551653	26551676	1	-	26780180	A375	viability (Avana lentiCRISPRv2)	AATGAGATAGAGCTTGCCCTCGG	RPS6KA1	ENSG00000117676	1.67498394101622	[]	[]	2	hSpCas9	negative selection	3554787
26557006	26557029	1	-	26780180	A375	viability (Avana lentiCRISPRv2)	AGGGTGGCTTGATCTCACGACGG	RPS6KA1	ENSG00000117676	1.13175255493492	[]	[]	1	hSpCas9	negative selection	3554788
26555599	26555622	1	+	26780180	A375	viability (Avana lentiCRISPRv2)	TCAAGCGGAATCCTGCCAACCGG	RPS6KA1	ENSG00000117676	-0.236314968410423	[]	[]	0	hSpCas9	negative selection	3554789
26529962	26529985	1	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCTAGTGCCTCTGGACCCGGAGG	RPS6KA1	ENSG00000117676	7.54545598639601	[]	[]	9	hSpCas9	negative selection	3554790
26555553	26555576	1	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCTTCAGTGCTCAGAAACTGGGG	RPS6KA1	ENSG00000117676	3.95692444630481	[]	[]	6	hSpCas9	negative selection	3554791
26553384	26553407	1	+	26780180	A375	viability (Avana lentiGuide)	TTTGCAGGTGATGTTCACGGAGG	RPS6KA1	ENSG00000117676	1.49692626729861	[]	[]	1	hSpCas9	negative selection	3663445
26551653	26551676	1	-	26780180	A375	viability (Avana lentiGuide)	AATGAGATAGAGCTTGCCCTCGG	RPS6KA1	ENSG00000117676	3.83256543495787	[]	[]	4	hSpCas9	negative selection	3663446
26557006	26557029	1	-	26780180	A375	viability (Avana lentiGuide)	AGGGTGGCTTGATCTCACGACGG	RPS6KA1	ENSG00000117676	6.19872559631665	[]	[]	5	hSpCas9	negative selection	3663447
26555599	26555622	1	+	26780180	A375	viability (Avana lentiGuide)	TCAAGCGGAATCCTGCCAACCGG	RPS6KA1	ENSG00000117676	-1.76829847268553	[]	[]	-3	hSpCas9	negative selection	3663448
26529962	26529985	1	+	26780180	A375	viability (Avana lentiGuide)	GCTAGTGCCTCTGGACCCGGAGG	RPS6KA1	ENSG00000117676	-9.22964625510551	[]	[]	-9	hSpCas9	negative selection	3663449
26555553	26555576	1	-	26780180	A375	viability (Avana lentiGuide)	GCTTCAGTGCTCAGAAACTGGGG	RPS6KA1	ENSG00000117676	3.94414882922355	[]	[]	4	hSpCas9	negative selection	3663450
26553384	26553407	1	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TTTGCAGGTGATGTTCACGGAGG	RPS6KA1	ENSG00000117676	0.11124571965020195	[4]	[5,4]	3	hSpCas9	positive selection	3772052
26551653	26551676	1	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AATGAGATAGAGCTTGCCCTCGG	RPS6KA1	ENSG00000117676	0.016204947768117428	[6]	[7,5]	0	hSpCas9	positive selection	3772053
26557006	26557029	1	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AGGGTGGCTTGATCTCACGACGG	RPS6KA1	ENSG00000117676	0.14214819726972952	[5]	[6,5]	4	hSpCas9	positive selection	3772054
26555599	26555622	1	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TCAAGCGGAATCCTGCCAACCGG	RPS6KA1	ENSG00000117676	0.14259490691769916	[4]	[4,4]	4	hSpCas9	positive selection	3772055
26529962	26529985	1	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCTAGTGCCTCTGGACCCGGAGG	RPS6KA1	ENSG00000117676	0.5428589604966759	[2]	[4,4]	9	hSpCas9	positive selection	3772056
26555553	26555576	1	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCTTCAGTGCTCAGAAACTGGGG	RPS6KA1	ENSG00000117676	0.08440490789323235	[4]	[4,4]	2	hSpCas9	positive selection	3772057
26553384	26553407	1	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TTTGCAGGTGATGTTCACGGAGG	RPS6KA1	ENSG00000117676	-0.188940345120589	[5]	[3,4]	-3	hSpCas9	positive selection	3880659
26551653	26551676	1	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AATGAGATAGAGCTTGCCCTCGG	RPS6KA1	ENSG00000117676	0.006331076725837825	[7]	[7,5]	0	hSpCas9	positive selection	3880660
26557006	26557029	1	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AGGGTGGCTTGATCTCACGACGG	RPS6KA1	ENSG00000117676	-0.16716044031498092	[5]	[4,4]	-2	hSpCas9	positive selection	3880661
26555599	26555622	1	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TCAAGCGGAATCCTGCCAACCGG	RPS6KA1	ENSG00000117676	0.3340964103341265	[4]	[4,5]	8	hSpCas9	positive selection	3880662
26529962	26529985	1	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCTAGTGCCTCTGGACCCGGAGG	RPS6KA1	ENSG00000117676	0.5512225064213044	[2]	[3,2]	9	hSpCas9	positive selection	3880663
26555553	26555576	1	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCTTCAGTGCTCAGAAACTGGGG	RPS6KA1	ENSG00000117676	0.2545934907267151	[5]	[5,5]	6	hSpCas9	positive selection	3880664
26553453	26553476	1	-	26780180	A375	viability	AAATGATACCCAGGCTGTGCAGG	RPS6KA1	ENSG00000117676	1.58274497007935	[]	[]	8	hSpCas9	negative selection	3990683
26536948	26536971	1	+	26780180	A375	viability	AGCTGGACTTCAGCCGTCCAAGG	RPS6KA1	ENSG00000117676	1.17560633777569	[]	[]	6	hSpCas9	negative selection	3990684
26551670	26551693	1	+	26780180	A375	viability	CTCATTCTGGACTTCCTGCGTGG	RPS6KA1	ENSG00000117676	1.40675700167934	[]	[]	7	hSpCas9	negative selection	3990685
26553483	26553506	1	-	26780180	A375	viability	TCACTCACTTCTCAGGCTTGAGG	RPS6KA1	ENSG00000117676	0.0694024550332381	[]	[]	0	hSpCas9	negative selection	3990686
26551684	26551707	1	-	26780180	A375	viability	TGAAGAGGTCCCCACCACGCAGG	RPS6KA1	ENSG00000117676	2.14563182165697	[]	[]	9	hSpCas9	negative selection	3990687
26536919	26536942	1	+	26780180	A375	viability	TTCCAGAATGGACAGACCTCAGG	RPS6KA1	ENSG00000117676	1.03712203872919	[]	[]	5	hSpCas9	negative selection	3990688
26553453	26553476	1	-	26780180	HT29	viability (GeCKOv2 library)	AAATGATACCCAGGCTGTGCAGG	RPS6KA1	ENSG00000117676	1.52513436964563	[]	[]	7	hSpCas9	negative selection	4098649
26536948	26536971	1	+	26780180	HT29	viability (GeCKOv2 library)	AGCTGGACTTCAGCCGTCCAAGG	RPS6KA1	ENSG00000117676	0.741129446497587	[]	[]	3	hSpCas9	negative selection	4098650
26551670	26551693	1	+	26780180	HT29	viability (GeCKOv2 library)	CTCATTCTGGACTTCCTGCGTGG	RPS6KA1	ENSG00000117676	1.33265460000782	[]	[]	6	hSpCas9	negative selection	4098651
26553483	26553506	1	-	26780180	HT29	viability (GeCKOv2 library)	TCACTCACTTCTCAGGCTTGAGG	RPS6KA1	ENSG00000117676	0.375678366311574	[]	[]	1	hSpCas9	negative selection	4098652
26551684	26551707	1	-	26780180	HT29	viability (GeCKOv2 library)	TGAAGAGGTCCCCACCACGCAGG	RPS6KA1	ENSG00000117676	3.05081105787955	[]	[]	9	hSpCas9	negative selection	4098653
26536919	26536942	1	+	26780180	HT29	viability (GeCKOv2 library)	TTCCAGAATGGACAGACCTCAGG	RPS6KA1	ENSG00000117676	1.15970365479842	[]	[]	5	hSpCas9	negative selection	4098654
26553453	26553476	1	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	AAATGATACCCAGGCTGTGCAGG	RPS6KA1	ENSG00000117676	0.31297409438558577	[3]	[2,4]	7	hSpCas9	positive selection	4167566
26536935	26536958	1	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	AAGTCCAGCTTCTTCCCCTGAGG	RPS6KA1	ENSG00000117676	-0.1002236820517334	[4]	[3,2]	-2	hSpCas9	positive selection	4167567
26551653	26551676	1	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	AATGAGATAGAGCTTGCCCTCGG	RPS6KA1	ENSG00000117676	0.01603528963285472	[5]	[3,3]	0	hSpCas9	positive selection	4167568
26536948	26536971	1	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	AGCTGGACTTCAGCCGTCCAAGG	RPS6KA1	ENSG00000117676	0.1586713598936769	[3]	[2,2]	4	hSpCas9	positive selection	4167569
26553444	26553467	1	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CCTGGATCACCTGCACAGCCTGG	RPS6KA1	ENSG00000117676	0.755768482540393	[3]	[6,2]	9	hSpCas9	positive selection	4167570
26551670	26551693	1	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CTCATTCTGGACTTCCTGCGTGG	RPS6KA1	ENSG00000117676	0.1251539379019081	[5]	[3,3]	3	hSpCas9	positive selection	4167571
26553405	26553428	1	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GGAGGATGTGAAGTTTTACCTGG	RPS6KA1	ENSG00000117676	-0.09850135856506015	[2]	[1,1]	-2	hSpCas9	positive selection	4167572
26551684	26551707	1	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TGAAGAGGTCCCCACCACGCAGG	RPS6KA1	ENSG00000117676	0.2958189017773834	[4]	[3,4]	7	hSpCas9	positive selection	4167573
26536919	26536942	1	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TTCCAGAATGGACAGACCTCAGG	RPS6KA1	ENSG00000117676	0.019315010649494563	[3]	[1,3]	0	hSpCas9	positive selection	4167575
26553453	26553476	1	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	AAATGATACCCAGGCTGTGCAGG	RPS6KA1	ENSG00000117676	-0.4073929917893184	[3]	[0,0,1,0]	-6	hSpCas9	positive selection	4231588
26536935	26536958	1	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	AAGTCCAGCTTCTTCCCCTGAGG	RPS6KA1	ENSG00000117676	1.0121995077532915	[3]	[0,0,5,3]	7	hSpCas9	positive selection	4231589
26551653	26551676	1	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	AATGAGATAGAGCTTGCCCTCGG	RPS6KA1	ENSG00000117676	0.2426759067930359	[5]	[4,3,5,0]	2	hSpCas9	positive selection	4231590
26536948	26536971	1	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	AGCTGGACTTCAGCCGTCCAAGG	RPS6KA1	ENSG00000117676	-0.1830215521683355	[3]	[0,0,2,0]	-3	hSpCas9	positive selection	4231591
26553444	26553467	1	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CCTGGATCACCTGCACAGCCTGG	RPS6KA1	ENSG00000117676	0.1454445885833633	[3]	[0,2,3,0]	1	hSpCas9	positive selection	4231592
26551670	26551693	1	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CTCATTCTGGACTTCCTGCGTGG	RPS6KA1	ENSG00000117676	1.4560652349554224	[3]	[2,4,5,5]	9	hSpCas9	positive selection	4231593
26553405	26553428	1	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GGAGGATGTGAAGTTTTACCTGG	RPS6KA1	ENSG00000117676	0.18632345516006754	[2]	[1,0,1,0]	1	hSpCas9	positive selection	4231594
26551684	26551707	1	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TGAAGAGGTCCCCACCACGCAGG	RPS6KA1	ENSG00000117676	1.1436645463454707	[4]	[3,3,4,3]	8	hSpCas9	positive selection	4231595
26536919	26536942	1	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TTCCAGAATGGACAGACCTCAGG	RPS6KA1	ENSG00000117676	1.220007198104012	[2]	[4,2,0,3]	8	hSpCas9	positive selection	4231597
26551684	26551707	1	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TGAAGAGGTCCCCACCACGCAGG	RPS6KA1	ENSG00000117676	-1.355294308719	[2]	[0,0]	-9	hSpCas9	positive selection	4295789
26536948	26536971	1	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AGCTGGACTTCAGCCGTCCAAGG	RPS6KA1	ENSG00000117676	0.017635120536273488	[3]	[3,1]	0	hSpCas9	positive selection	4295790
26551670	26551693	1	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CTCATTCTGGACTTCCTGCGTGG	RPS6KA1	ENSG00000117676	0.27240061080900746	[2]	[2,2]	5	hSpCas9	positive selection	4295791
26536919	26536942	1	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TTCCAGAATGGACAGACCTCAGG	RPS6KA1	ENSG00000117676	-0.19926324993451539	[3]	[3,1]	-4	hSpCas9	positive selection	4360042
26553453	26553476	1	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AAATGATACCCAGGCTGTGCAGG	RPS6KA1	ENSG00000117676	-0.1026021275500813	[2]	[2,0]	-2	hSpCas9	positive selection	4360043
26553483	26553506	1	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TCACTCACTTCTCAGGCTTGAGG	RPS6KA1	ENSG00000117676	0.4720119971689699	[3]	[4,4]	8	hSpCas9	positive selection	4360044
26555614	26555636	1	-	27760321	OCIAML3	viability	GGCTGCTTACCGAGCCGGTTGG	RPS6KA1	ENSG00000117676	-1.9294411219451202	[420,325]	[53,104]	-9	hSpCas9	negative selection	4435943
26546895	26546917	1	+	27760321	OCIAML3	viability	TCACGCACCACGTCAAGGCTGG	RPS6KA1	ENSG00000117676	-1.0809858249246593	[586,463]	[222,153]	-7	hSpCas9	negative selection	4435944
26551393	26551415	1	-	27760321	OCIAML3	viability	TCCGGACGCGGTCACGTACTGG	RPS6KA1	ENSG00000117676	-2.7068887378975672	[394,356]	[44,44]	-9	hSpCas9	negative selection	4435945
26551648	26551670	1	-	27760321	OCIAML3	viability	ATAGAGCTTGCCCTCGGTCTGG	RPS6KA1	ENSG00000117676	-2.0152563411393603	[766,619]	[109,163]	-9	hSpCas9	negative selection	4435946
26554674	26554696	1	+	27760321	OCIAML3	viability	CTGAGGTCGTCAACCGCCAGGG	RPS6KA1	ENSG00000117676	-1.0295862972052823	[659,569]	[214,260]	-7	hSpCas9	negative selection	4435947
26555614	26555636	1	-	27760321	OCIAML2	viability	GGCTGCTTACCGAGCCGGTTGG	RPS6KA1	ENSG00000117676	-1.1838113821235672	[420,325]	[103,168]	-8	hSpCas9	negative selection	4519406
26546895	26546917	1	+	27760321	OCIAML2	viability	TCACGCACCACGTCAAGGCTGG	RPS6KA1	ENSG00000117676	-0.7705193612535199	[586,463]	[197,312]	-7	hSpCas9	negative selection	4519407
26551393	26551415	1	-	27760321	OCIAML2	viability	TCCGGACGCGGTCACGTACTGG	RPS6KA1	ENSG00000117676	-1.1797460253642538	[394,356]	[90,190]	-8	hSpCas9	negative selection	4519408
26551648	26551670	1	-	27760321	OCIAML2	viability	ATAGAGCTTGCCCTCGGTCTGG	RPS6KA1	ENSG00000117676	-1.7512608655343673	[766,619]	[119,225]	-9	hSpCas9	negative selection	4519409
26554674	26554696	1	+	27760321	OCIAML2	viability	CTGAGGTCGTCAACCGCCAGGG	RPS6KA1	ENSG00000117676	-1.5835156267785497	[659,569]	[105,243]	-8	hSpCas9	negative selection	4519410
26555614	26555636	1	-	27760321	MV411	viability	GGCTGCTTACCGAGCCGGTTGG	RPS6KA1	ENSG00000117676	-0.47720790481806347	[420,325]	[164,191]	-3	hSpCas9	negative selection	4602869
26546895	26546917	1	+	27760321	MV411	viability	TCACGCACCACGTCAAGGCTGG	RPS6KA1	ENSG00000117676	-0.17562869189738983	[586,463]	[171,504]	-1	hSpCas9	negative selection	4602870
26551393	26551415	1	-	27760321	MV411	viability	TCCGGACGCGGTCACGTACTGG	RPS6KA1	ENSG00000117676	-1.1494947777172515	[394,356]	[54,196]	-6	hSpCas9	negative selection	4602871
26551648	26551670	1	-	27760321	MV411	viability	ATAGAGCTTGCCCTCGGTCTGG	RPS6KA1	ENSG00000117676	-0.2094141153421752	[766,619]	[230,637]	-1	hSpCas9	negative selection	4602872
26554674	26554696	1	+	27760321	MV411	viability	CTGAGGTCGTCAACCGCCAGGG	RPS6KA1	ENSG00000117676	0.24492751979249416	[659,569]	[507,436]	1	hSpCas9	negative selection	4602873
26555614	26555636	1	-	27760321	HL60	viability	GGCTGCTTACCGAGCCGGTTGG	RPS6KA1	ENSG00000117676	-1.927750514768478	[420,325]	[66,92]	-9	hSpCas9	negative selection	4686332
26546895	26546917	1	+	27760321	HL60	viability	TCACGCACCACGTCAAGGCTGG	RPS6KA1	ENSG00000117676	-0.7019212143113955	[586,463]	[219,306]	-6	hSpCas9	negative selection	4686333
26551393	26551415	1	-	27760321	HL60	viability	TCCGGACGCGGTCACGTACTGG	RPS6KA1	ENSG00000117676	-0.549330225982642	[394,356]	[116,307]	-5	hSpCas9	negative selection	4686334
26551648	26551670	1	-	27760321	HL60	viability	ATAGAGCTTGCCCTCGGTCTGG	RPS6KA1	ENSG00000117676	-1.656993520460954	[766,619]	[150,207]	-9	hSpCas9	negative selection	4686335
26554674	26554696	1	+	27760321	HL60	viability	CTGAGGTCGTCAACCGCCAGGG	RPS6KA1	ENSG00000117676	-0.508498218060751	[659,569]	[374,327]	-5	hSpCas9	negative selection	4686336
26555614	26555636	1	-	27760321	HT1080	viability	GGCTGCTTACCGAGCCGGTTGG	RPS6KA1	ENSG00000117676	1.5679620103086505	[325,254]	[472,200]	8	hSpCas9	negative selection	4769795
26546895	26546917	1	+	27760321	HT1080	viability	TCACGCACCACGTCAAGGCTGG	RPS6KA1	ENSG00000117676	0.2648714342530471	[463,361]	[211,181]	1	hSpCas9	negative selection	4769796
26551393	26551415	1	-	27760321	HT1080	viability	TCCGGACGCGGTCACGTACTGG	RPS6KA1	ENSG00000117676	-0.29235471598094565	[356,278]	[112,92]	-1	hSpCas9	negative selection	4769797
26551648	26551670	1	-	27760321	HT1080	viability	ATAGAGCTTGCCCTCGGTCTGG	RPS6KA1	ENSG00000117676	-2.5386329592514754	[619,483]	[2,75]	-7	hSpCas9	negative selection	4769798
26554674	26554696	1	+	27760321	HT1080	viability	CTGAGGTCGTCAACCGCCAGGG	RPS6KA1	ENSG00000117676	-0.5262469508418554	[569,444]	[158,119]	-2	hSpCas9	negative selection	4769799
26555614	26555636	1	-	27760321	HT29	viability after 7 days	GGCTGCTTACCGAGCCGGTTGG	RPS6KA1	ENSG00000117676	-0.0894234123381486	[325,254]	[540,191,346]	-1	hSpCas9	negative selection	4853258
26546895	26546917	1	+	27760321	HT29	viability after 7 days	TCACGCACCACGTCAAGGCTGG	RPS6KA1	ENSG00000117676	0.24687421114208147	[463,361]	[671,582,639]	4	hSpCas9	negative selection	4853259
26551393	26551415	1	-	27760321	HT29	viability after 7 days	TCCGGACGCGGTCACGTACTGG	RPS6KA1	ENSG00000117676	0.3664315628603433	[356,278]	[578,576,434]	5	hSpCas9	negative selection	4853260
26551648	26551670	1	-	27760321	HT29	viability after 7 days	ATAGAGCTTGCCCTCGGTCTGG	RPS6KA1	ENSG00000117676	0.5299425538362762	[619,483]	[1238,1083,787]	7	hSpCas9	negative selection	4853261
26554674	26554696	1	+	27760321	HT29	viability after 7 days	CTGAGGTCGTCAACCGCCAGGG	RPS6KA1	ENSG00000117676	0.11982926027531715	[569,444]	[931,839,395]	1	hSpCas9	negative selection	4853262
26555614	26555636	1	-	27760321	HT29	viability after 25 days	GGCTGCTTACCGAGCCGGTTGG	RPS6KA1	ENSG00000117676	0.3552796641760081	[325,254]	[472,394,399]	4	hSpCas9	negative selection	4936721
26546895	26546917	1	+	27760321	HT29	viability after 25 days	TCACGCACCACGTCAAGGCTGG	RPS6KA1	ENSG00000117676	0.4429484383831656	[463,361]	[575,683,670]	5	hSpCas9	negative selection	4936722
26551393	26551415	1	-	27760321	HT29	viability after 25 days	TCCGGACGCGGTCACGTACTGG	RPS6KA1	ENSG00000117676	0.6927264638796475	[356,278]	[598,416,762]	7	hSpCas9	negative selection	4936723
26551648	26551670	1	-	27760321	HT29	viability after 25 days	ATAGAGCTTGCCCTCGGTCTGG	RPS6KA1	ENSG00000117676	0.5139092833524442	[619,483]	[775,763,1199]	5	hSpCas9	negative selection	4936724
26554674	26554696	1	+	27760321	HT29	viability after 25 days	CTGAGGTCGTCAACCGCCAGGG	RPS6KA1	ENSG00000117676	0.7134859332164494	[569,444]	[931,994,922]	7	hSpCas9	negative selection	4936725
26555614	26555636	1	-	27760321	HT29	viability after 22 days	GGCTGCTTACCGAGCCGGTTGG	RPS6KA1	ENSG00000117676	0.39407607255963945	[325,254]	[523,448,347]	4	hSpCas9	negative selection	5020184
26546895	26546917	1	+	27760321	HT29	viability after 22 days	TCACGCACCACGTCAAGGCTGG	RPS6KA1	ENSG00000117676	0.5627744146827938	[463,361]	[926,545,635]	6	hSpCas9	negative selection	5020185
26551393	26551415	1	-	27760321	HT29	viability after 22 days	TCCGGACGCGGTCACGTACTGG	RPS6KA1	ENSG00000117676	0.5711792988670988	[356,278]	[529,471,637]	6	hSpCas9	negative selection	5020186
26551648	26551670	1	-	27760321	HT29	viability after 22 days	ATAGAGCTTGCCCTCGGTCTGG	RPS6KA1	ENSG00000117676	0.5149456403417475	[619,483]	[782,633,1325]	5	hSpCas9	negative selection	5020187
26554674	26554696	1	+	27760321	HT29	viability after 22 days	CTGAGGTCGTCAACCGCCAGGG	RPS6KA1	ENSG00000117676	0.555900002396283	[569,444]	[840,891,854]	6	hSpCas9	negative selection	5020188
26555614	26555636	1	-	27760321	HT29	viability after 19 days	GGCTGCTTACCGAGCCGGTTGG	RPS6KA1	ENSG00000117676	0.8193091614350221	[325,254]	[636,676,454]	8	hSpCas9	negative selection	5103647
26546895	26546917	1	+	27760321	HT29	viability after 19 days	TCACGCACCACGTCAAGGCTGG	RPS6KA1	ENSG00000117676	0.5883881457073203	[463,361]	[864,617,664]	6	hSpCas9	negative selection	5103648
26551393	26551415	1	-	27760321	HT29	viability after 19 days	TCCGGACGCGGTCACGTACTGG	RPS6KA1	ENSG00000117676	0.5836808432697107	[356,278]	[435,521,660]	6	hSpCas9	negative selection	5103649
26551648	26551670	1	-	27760321	HT29	viability after 19 days	ATAGAGCTTGCCCTCGGTCTGG	RPS6KA1	ENSG00000117676	0.6452797455424747	[619,483]	[1292,1046,665]	6	hSpCas9	negative selection	5103650
26554674	26554696	1	+	27760321	HT29	viability after 19 days	CTGAGGTCGTCAACCGCCAGGG	RPS6KA1	ENSG00000117676	0.633116047963598	[569,444]	[1080,713,922]	6	hSpCas9	negative selection	5103651
26555614	26555636	1	-	27760321	HT29	viability after 16 days	GGCTGCTTACCGAGCCGGTTGG	RPS6KA1	ENSG00000117676	0.4282754993628818	[325,254]	[505,537,271]	5	hSpCas9	negative selection	5187110
26546895	26546917	1	+	27760321	HT29	viability after 16 days	TCACGCACCACGTCAAGGCTGG	RPS6KA1	ENSG00000117676	0.20108726870459498	[463,361]	[381,657,535]	2	hSpCas9	negative selection	5187111
26551393	26551415	1	-	27760321	HT29	viability after 16 days	TCCGGACGCGGTCACGTACTGG	RPS6KA1	ENSG00000117676	0.36103461241165613	[356,278]	[574,342,466]	4	hSpCas9	negative selection	5187112
26551648	26551670	1	-	27760321	HT29	viability after 16 days	ATAGAGCTTGCCCTCGGTCTGG	RPS6KA1	ENSG00000117676	0.7515652344310463	[619,483]	[1533,651,989]	8	hSpCas9	negative selection	5187113
26554674	26554696	1	+	27760321	HT29	viability after 16 days	CTGAGGTCGTCAACCGCCAGGG	RPS6KA1	ENSG00000117676	0.5139043490948592	[569,444]	[804,911,711]	6	hSpCas9	negative selection	5187114
26555614	26555636	1	-	27760321	HT29	viability after 13 days	GGCTGCTTACCGAGCCGGTTGG	RPS6KA1	ENSG00000117676	0.41774925035454913	[325,254]	[478,444,427]	5	hSpCas9	negative selection	5270573
26546895	26546917	1	+	27760321	HT29	viability after 13 days	TCACGCACCACGTCAAGGCTGG	RPS6KA1	ENSG00000117676	0.15619952545696675	[463,361]	[551,386,654]	2	hSpCas9	negative selection	5270574
26551393	26551415	1	-	27760321	HT29	viability after 13 days	TCCGGACGCGGTCACGTACTGG	RPS6KA1	ENSG00000117676	0.13984118099753387	[356,278]	[359,392,462]	1	hSpCas9	negative selection	5270575
26551648	26551670	1	-	27760321	HT29	viability after 13 days	ATAGAGCTTGCCCTCGGTCTGG	RPS6KA1	ENSG00000117676	0.5797795223345074	[619,483]	[1029,899,941]	7	hSpCas9	negative selection	5270576
26554674	26554696	1	+	27760321	HT29	viability after 13 days	CTGAGGTCGTCAACCGCCAGGG	RPS6KA1	ENSG00000117676	0.5169283277467798	[569,444]	[995,911,631]	6	hSpCas9	negative selection	5270577
26555614	26555636	1	-	27760321	HT29	viability after 10 days	GGCTGCTTACCGAGCCGGTTGG	RPS6KA1	ENSG00000117676	0.46772674224884975	[325,254]	[472,395,629]	6	hSpCas9	negative selection	5354036
26546895	26546917	1	+	27760321	HT29	viability after 10 days	TCACGCACCACGTCAAGGCTGG	RPS6KA1	ENSG00000117676	-0.14722435500826297	[463,361]	[539,496,362]	-2	hSpCas9	negative selection	5354037
26551393	26551415	1	-	27760321	HT29	viability after 10 days	TCCGGACGCGGTCACGTACTGG	RPS6KA1	ENSG00000117676	0.34172676114915734	[356,278]	[481,361,657]	4	hSpCas9	negative selection	5354038
26551648	26551670	1	-	27760321	HT29	viability after 10 days	ATAGAGCTTGCCCTCGGTCTGG	RPS6KA1	ENSG00000117676	0.05863189272555713	[619,483]	[764,650,734]	0	hSpCas9	negative selection	5354039
26554674	26554696	1	+	27760321	HT29	viability after 10 days	CTGAGGTCGTCAACCGCCAGGG	RPS6KA1	ENSG00000117676	0.04820368101765404	[569,444]	[753,541,665]	0	hSpCas9	negative selection	5354040
26555614	26555636	1	-	27760321	MOLM13	viability	GGCTGCTTACCGAGCCGGTTGG	RPS6KA1	ENSG00000117676	-3.1693985792265362	[420,325]	[39,8]	-9	hSpCas9	negative selection	5437499
26546895	26546917	1	+	27760321	MOLM13	viability	TCACGCACCACGTCAAGGCTGG	RPS6KA1	ENSG00000117676	-1.5665312701055316	[586,463]	[146,58]	-7	hSpCas9	negative selection	5437500
26551393	26551415	1	-	27760321	MOLM13	viability	TCCGGACGCGGTCACGTACTGG	RPS6KA1	ENSG00000117676	-0.4935633593548332	[394,356]	[1,276]	-3	hSpCas9	negative selection	5437501
26551648	26551670	1	-	27760321	MOLM13	viability	ATAGAGCTTGCCCTCGGTCTGG	RPS6KA1	ENSG00000117676	-1.5508830438618881	[766,619]	[141,124]	-7	hSpCas9	negative selection	5437502
26554674	26554696	1	+	27760321	MOLM13	viability	CTGAGGTCGTCAACCGCCAGGG	RPS6KA1	ENSG00000117676	-1.0675920796737186	[659,569]	[304,45]	-6	hSpCas9	negative selection	5437503
26529802	26529825	1	+	27661255	K562	viability	GGAGCGCGAGGGGCTCGGGGGGG	RPS6KA1	ENSG00000117676	-1.095591689086615	[387,573]	[177,178]	-8	dCas9-KRAB	negative selection	5508617
26530021	26530044	1	+	27661255	K562	viability	GCGAGCCCGGATCCTCACAGGGG	RPS6KA1	ENSG00000117676	-0.21585499650614215	[423,491]	[365,269]	-6	dCas9-KRAB	negative selection	5508618
26546235	26546258	1	+	27661255	K562	viability	GGGAGGGTAGAGTCCTGGAAAGG	RPS6KA1	ENSG00000117676	0.06686083227550599	[953,1235]	[1135,720]	2	dCas9-KRAB	negative selection	5508619
26546246	26546269	1	+	27661255	K562	viability	GTCCTGGAAAGGCTAGGACCTGG	RPS6KA1	ENSG00000117676	0.33967575758860047	[366,430]	[426,380]	9	dCas9-KRAB	negative selection	5508620
26530179	26530202	1	-	27661255	K562	viability	GGCTATGGCGGGGAGGTAGTCGG	RPS6KA1	ENSG00000117676	0.6204236511382796	[346,298]	[475,330]	9	dCas9-KRAB	negative selection	5508621
26551684	26551707	1	-	27260156	BXPC3	viability	TGAAGAGGTCCCCACCACGCAGG	RPS6KA1	ENSG00000117676	0.09762970221620978	[435]	[513,367,473,610]	2	hSpCas9	negative selection	5568249
26536948	26536971	1	+	27260156	BXPC3	viability	AGCTGGACTTCAGCCGTCCAAGG	RPS6KA1	ENSG00000117676	0.23085856115985492	[545]	[615,806,561,687]	5	hSpCas9	negative selection	5568250
26551670	26551693	1	+	27260156	BXPC3	viability	CTCATTCTGGACTTCCTGCGTGG	RPS6KA1	ENSG00000117676	0.011780367593208385	[416]	[360,518,414,466]	0	hSpCas9	negative selection	5568251
26536919	26536942	1	+	27260156	BXPC3	viability	TTCCAGAATGGACAGACCTCAGG	RPS6KA1	ENSG00000117676	0.13225298774899008	[714]	[947,622,815,890]	3	hSpCas9	negative selection	5632502
26553453	26553476	1	-	27260156	BXPC3	viability	AAATGATACCCAGGCTGTGCAGG	RPS6KA1	ENSG00000117676	-0.033387523487889426	[319]	[356,341,275,324]	0	hSpCas9	negative selection	5632503
26553483	26553506	1	-	27260156	BXPC3	viability	TCACTCACTTCTCAGGCTTGAGG	RPS6KA1	ENSG00000117676	-0.07801426627552188	[931]	[753,871,1146,940]	-2	hSpCas9	negative selection	5632504
26551684	26551707	1	-	27260156	A673	viability	TGAAGAGGTCCCCACCACGCAGG	RPS6KA1	ENSG00000117676	0.46187242876175655	[435]	[667,591,640,994]	9	hSpCas9	negative selection	5689500
26536948	26536971	1	+	27260156	A673	viability	AGCTGGACTTCAGCCGTCCAAGG	RPS6KA1	ENSG00000117676	0.21102105621069883	[545]	[825,647,797,772]	5	hSpCas9	negative selection	5689501
26551670	26551693	1	+	27260156	A673	viability	CTCATTCTGGACTTCCTGCGTGG	RPS6KA1	ENSG00000117676	0.3183756040062954	[416]	[636,605,615,639]	7	hSpCas9	negative selection	5689502
26536919	26536942	1	+	27260156	A673	viability	TTCCAGAATGGACAGACCTCAGG	RPS6KA1	ENSG00000117676	0.09067950824825843	[714]	[993,911,901,852]	2	hSpCas9	negative selection	5753753
26553453	26553476	1	-	27260156	A673	viability	AAATGATACCCAGGCTGTGCAGG	RPS6KA1	ENSG00000117676	0.10711988893724239	[319]	[436,335,511,370]	2	hSpCas9	negative selection	5753754
26553483	26553506	1	-	27260156	A673	viability	TCACTCACTTCTCAGGCTTGAGG	RPS6KA1	ENSG00000117676	0.13874273929988	[931]	[1172,1185,1170,1399]	3	hSpCas9	negative selection	5753755
26551684	26551707	1	-	27260156	A375	viability	TGAAGAGGTCCCCACCACGCAGG	RPS6KA1	ENSG00000117676	0.5406130590844356	[435]	[590,636,942,769]	7	hSpCas9	negative selection	5810751
26536948	26536971	1	+	27260156	A375	viability	AGCTGGACTTCAGCCGTCCAAGG	RPS6KA1	ENSG00000117676	0.29827021898350414	[545]	[693,1039,801,648]	4	hSpCas9	negative selection	5810752
26551670	26551693	1	+	27260156	A375	viability	CTCATTCTGGACTTCCTGCGTGG	RPS6KA1	ENSG00000117676	-0.11812226180552415	[416]	[554,548,402,316]	-2	hSpCas9	negative selection	5810753
26536919	26536942	1	+	27260156	A375	viability	TTCCAGAATGGACAGACCTCAGG	RPS6KA1	ENSG00000117676	0.09702462713992577	[714]	[938,1079,889,708]	1	hSpCas9	negative selection	5875004
26553453	26553476	1	-	27260156	A375	viability	AAATGATACCCAGGCTGTGCAGG	RPS6KA1	ENSG00000117676	0.19094939019824353	[319]	[340,579,362,439]	2	hSpCas9	negative selection	5875005
26553483	26553506	1	-	27260156	A375	viability	TCACTCACTTCTCAGGCTTGAGG	RPS6KA1	ENSG00000117676	0.10309923770597307	[931]	[1160,1241,1291,1006]	1	hSpCas9	negative selection	5875006
26551684	26551707	1	-	27260156	COLO741	viability	TGAAGAGGTCCCCACCACGCAGG	RPS6KA1	ENSG00000117676	0.29471008811413224	[435]	[895,666,515]	6	hSpCas9	negative selection	5932002
26536948	26536971	1	+	27260156	COLO741	viability	AGCTGGACTTCAGCCGTCCAAGG	RPS6KA1	ENSG00000117676	-0.13315621647256373	[545]	[817,509,596]	-3	hSpCas9	negative selection	5932003
26551670	26551693	1	+	27260156	COLO741	viability	CTCATTCTGGACTTCCTGCGTGG	RPS6KA1	ENSG00000117676	0.4277521753129656	[416]	[822,599,732]	8	hSpCas9	negative selection	5932004
26536919	26536942	1	+	27260156	COLO741	viability	TTCCAGAATGGACAGACCTCAGG	RPS6KA1	ENSG00000117676	0.1285683313068643	[714]	[1103,1002,902]	2	hSpCas9	negative selection	5996255
26553453	26553476	1	-	27260156	COLO741	viability	AAATGATACCCAGGCTGTGCAGG	RPS6KA1	ENSG00000117676	-0.3617233291713944	[319]	[363,335,261]	-6	hSpCas9	negative selection	5996256
26553483	26553506	1	-	27260156	COLO741	viability	TCACTCACTTCTCAGGCTTGAGG	RPS6KA1	ENSG00000117676	0.17089562816355308	[931]	[1621,1385,1055]	3	hSpCas9	negative selection	5996257
26551684	26551707	1	-	27260156	CAL120	viability	TGAAGAGGTCCCCACCACGCAGG	RPS6KA1	ENSG00000117676	0.5722017759330267	[435]	[1363,583,559]	8	hSpCas9	negative selection	6053253
26536948	26536971	1	+	27260156	CAL120	viability	AGCTGGACTTCAGCCGTCCAAGG	RPS6KA1	ENSG00000117676	0.6516874330829757	[545]	[1579,1085,620]	8	hSpCas9	negative selection	6053254
26551670	26551693	1	+	27260156	CAL120	viability	CTCATTCTGGACTTCCTGCGTGG	RPS6KA1	ENSG00000117676	0.287406899435361	[416]	[665,629,608]	4	hSpCas9	negative selection	6053255
26536919	26536942	1	+	27260156	CAL120	viability	TTCCAGAATGGACAGACCTCAGG	RPS6KA1	ENSG00000117676	0.18630049152595562	[714]	[1202,1218,649]	2	hSpCas9	negative selection	6117506
26553453	26553476	1	-	27260156	CAL120	viability	AAATGATACCCAGGCTGTGCAGG	RPS6KA1	ENSG00000117676	-0.2798107998274437	[319]	[383,319,288]	-4	hSpCas9	negative selection	6117507
26553483	26553506	1	-	27260156	CAL120	viability	TCACTCACTTCTCAGGCTTGAGG	RPS6KA1	ENSG00000117676	0.3717110722839908	[931]	[1308,1529,1630]	5	hSpCas9	negative selection	6117508
26551684	26551707	1	-	27260156	CADOES1	viability	TGAAGAGGTCCCCACCACGCAGG	RPS6KA1	ENSG00000117676	0.45972467675693834	[435]	[430,580,586,634]	7	hSpCas9	negative selection	6174504
26536948	26536971	1	+	27260156	CADOES1	viability	AGCTGGACTTCAGCCGTCCAAGG	RPS6KA1	ENSG00000117676	0.5752919244451755	[545]	[778,647,847,750]	8	hSpCas9	negative selection	6174505
26551670	26551693	1	+	27260156	CADOES1	viability	CTCATTCTGGACTTCCTGCGTGG	RPS6KA1	ENSG00000117676	0.17375122635394893	[416]	[629,441,276,398]	3	hSpCas9	negative selection	6174506
26536919	26536942	1	+	27260156	CADOES1	viability	TTCCAGAATGGACAGACCTCAGG	RPS6KA1	ENSG00000117676	0.13619223141543602	[714]	[826,490,606,1007]	2	hSpCas9	negative selection	6238757
26553453	26553476	1	-	27260156	CADOES1	viability	AAATGATACCCAGGCTGTGCAGG	RPS6KA1	ENSG00000117676	0.034207553694001525	[319]	[289,219,400,307]	0	hSpCas9	negative selection	6238758
26553483	26553506	1	-	27260156	CADOES1	viability	TCACTCACTTCTCAGGCTTGAGG	RPS6KA1	ENSG00000117676	0.07685610310542323	[931]	[853,998,846,958]	1	hSpCas9	negative selection	6238759
26551684	26551707	1	-	27260156	EWS502	viability	TGAAGAGGTCCCCACCACGCAGG	RPS6KA1	ENSG00000117676	0.3135933831608345	[435]	[643,620,477,535]	5	hSpCas9	negative selection	6295755
26536948	26536971	1	+	27260156	EWS502	viability	AGCTGGACTTCAGCCGTCCAAGG	RPS6KA1	ENSG00000117676	0.24697774004334339	[545]	[572,826,618,733]	4	hSpCas9	negative selection	6295756
26551670	26551693	1	+	27260156	EWS502	viability	CTCATTCTGGACTTCCTGCGTGG	RPS6KA1	ENSG00000117676	0.42669831726002266	[416]	[774,508,493,572]	7	hSpCas9	negative selection	6295757
26536919	26536942	1	+	27260156	EWS502	viability	TTCCAGAATGGACAGACCTCAGG	RPS6KA1	ENSG00000117676	0.3335839013260409	[714]	[724,1062,1159,886]	6	hSpCas9	negative selection	6360008
26553453	26553476	1	-	27260156	EWS502	viability	AAATGATACCCAGGCTGTGCAGG	RPS6KA1	ENSG00000117676	0.22130916764020303	[319]	[401,224,427,540]	4	hSpCas9	negative selection	6360009
26553483	26553506	1	-	27260156	EWS502	viability	TCACTCACTTCTCAGGCTTGAGG	RPS6KA1	ENSG00000117676	0.012237922541077473	[931]	[1058,910,1061,938]	0	hSpCas9	negative selection	6360010
26551684	26551707	1	-	27260156	EW8	viability	TGAAGAGGTCCCCACCACGCAGG	RPS6KA1	ENSG00000117676	0.6164130833668107	[435]	[616,566,534,455]	9	hSpCas9	negative selection	6417006
26536948	26536971	1	+	27260156	EW8	viability	AGCTGGACTTCAGCCGTCCAAGG	RPS6KA1	ENSG00000117676	0.19117369577319837	[545]	[761,446,557,271]	3	hSpCas9	negative selection	6417007
26551670	26551693	1	+	27260156	EW8	viability	CTCATTCTGGACTTCCTGCGTGG	RPS6KA1	ENSG00000117676	0.07541017309467571	[416]	[273,461,360,316]	1	hSpCas9	negative selection	6417008
26536919	26536942	1	+	27260156	EW8	viability	TTCCAGAATGGACAGACCTCAGG	RPS6KA1	ENSG00000117676	-0.14839765926074933	[714]	[765,441,351,584]	-3	hSpCas9	negative selection	6481259
26553453	26553476	1	-	27260156	EW8	viability	AAATGATACCCAGGCTGTGCAGG	RPS6KA1	ENSG00000117676	-0.10111616194013384	[319]	[250,252,148,329]	-2	hSpCas9	negative selection	6481260
26553483	26553506	1	-	27260156	EW8	viability	TCACTCACTTCTCAGGCTTGAGG	RPS6KA1	ENSG00000117676	-0.05602931695507973	[931]	[698,855,653,704]	-1	hSpCas9	negative selection	6481261
26551684	26551707	1	-	27260156	CORL105	viability	TGAAGAGGTCCCCACCACGCAGG	RPS6KA1	ENSG00000117676	0.10185617276951739	[435]	[590,431,745,456]	2	hSpCas9	negative selection	6538257
26536948	26536971	1	+	27260156	CORL105	viability	AGCTGGACTTCAGCCGTCCAAGG	RPS6KA1	ENSG00000117676	0.0677325006408977	[545]	[734,536,744,678]	1	hSpCas9	negative selection	6538258
26551670	26551693	1	+	27260156	CORL105	viability	CTCATTCTGGACTTCCTGCGTGG	RPS6KA1	ENSG00000117676	0.07704154972105814	[416]	[407,674,495,470]	1	hSpCas9	negative selection	6538259
26536919	26536942	1	+	27260156	CORL105	viability	TTCCAGAATGGACAGACCTCAGG	RPS6KA1	ENSG00000117676	-0.044964174391413314	[714]	[744,732,1018,779]	-1	hSpCas9	negative selection	6602510
26553453	26553476	1	-	27260156	CORL105	viability	AAATGATACCCAGGCTGTGCAGG	RPS6KA1	ENSG00000117676	0.24195293517633287	[319]	[277,311,632,574]	4	hSpCas9	negative selection	6602511
26553483	26553506	1	-	27260156	CORL105	viability	TCACTCACTTCTCAGGCTTGAGG	RPS6KA1	ENSG00000117676	-0.06450364499893435	[931]	[998,1061,1198,935]	-1	hSpCas9	negative selection	6602512
26551684	26551707	1	-	27260156	HS294T	viability	TGAAGAGGTCCCCACCACGCAGG	RPS6KA1	ENSG00000117676	-0.028517993499628663	[435]	[144,140,113,282]	0	hSpCas9	negative selection	6659508
26536948	26536971	1	+	27260156	HS294T	viability	AGCTGGACTTCAGCCGTCCAAGG	RPS6KA1	ENSG00000117676	0.8288456923366164	[545]	[453,538,198,276]	9	hSpCas9	negative selection	6659509
26551670	26551693	1	+	27260156	HS294T	viability	CTCATTCTGGACTTCCTGCGTGG	RPS6KA1	ENSG00000117676	-0.5503232032556875	[416]	[101,89,96,160]	-7	hSpCas9	negative selection	6659510
26536919	26536942	1	+	27260156	HS294T	viability	TTCCAGAATGGACAGACCTCAGG	RPS6KA1	ENSG00000117676	-0.4275432208090506	[714]	[226,161,210,223]	-6	hSpCas9	negative selection	6723761
26553453	26553476	1	-	27260156	HS294T	viability	AAATGATACCCAGGCTGTGCAGG	RPS6KA1	ENSG00000117676	0.14154229896602466	[319]	[132,176,84,151]	2	hSpCas9	negative selection	6723762
26553483	26553506	1	-	27260156	HS294T	viability	TCACTCACTTCTCAGGCTTGAGG	RPS6KA1	ENSG00000117676	0.5181336893285969	[931]	[512,370,506,708]	7	hSpCas9	negative selection	6723763
26551684	26551707	1	-	27260156	HCC44	viability	TGAAGAGGTCCCCACCACGCAGG	RPS6KA1	ENSG00000117676	0.7398458994478045	[435]	[849,690,985,809]	9	hSpCas9	negative selection	6780759
26536948	26536971	1	+	27260156	HCC44	viability	AGCTGGACTTCAGCCGTCCAAGG	RPS6KA1	ENSG00000117676	0.0587513403871317	[545]	[837,411,875,535]	0	hSpCas9	negative selection	6780760
26551670	26551693	1	+	27260156	HCC44	viability	CTCATTCTGGACTTCCTGCGTGG	RPS6KA1	ENSG00000117676	0.18950809106618796	[416]	[497,506,670,495]	3	hSpCas9	negative selection	6780761
26536919	26536942	1	+	27260156	HCC44	viability	TTCCAGAATGGACAGACCTCAGG	RPS6KA1	ENSG00000117676	-0.09495523777354253	[714]	[882,546,957,711]	-1	hSpCas9	negative selection	6845012
26553453	26553476	1	-	27260156	HCC44	viability	AAATGATACCCAGGCTGTGCAGG	RPS6KA1	ENSG00000117676	-0.14837402268196054	[319]	[360,426,330,178]	-2	hSpCas9	negative selection	6845013
26553483	26553506	1	-	27260156	HCC44	viability	TCACTCACTTCTCAGGCTTGAGG	RPS6KA1	ENSG00000117676	0.01043689238427814	[931]	[890,1062,1273,1031]	0	hSpCas9	negative selection	6845014
26551684	26551707	1	-	27260156	G402	viability	TGAAGAGGTCCCCACCACGCAGG	RPS6KA1	ENSG00000117676	0.6332621483088285	[435]	[1025,691,843,759]	7	hSpCas9	negative selection	6902010
26536948	26536971	1	+	27260156	G402	viability	AGCTGGACTTCAGCCGTCCAAGG	RPS6KA1	ENSG00000117676	0.25111065509573754	[545]	[583,898,963,701]	3	hSpCas9	negative selection	6902011
26551670	26551693	1	+	27260156	G402	viability	CTCATTCTGGACTTCCTGCGTGG	RPS6KA1	ENSG00000117676	0.5755597085161517	[416]	[710,739,891,682]	7	hSpCas9	negative selection	6902012
26536919	26536942	1	+	27260156	G402	viability	TTCCAGAATGGACAGACCTCAGG	RPS6KA1	ENSG00000117676	-0.1501631512918289	[714]	[752,869,587,923]	-2	hSpCas9	negative selection	6966263
26553453	26553476	1	-	27260156	G402	viability	AAATGATACCCAGGCTGTGCAGG	RPS6KA1	ENSG00000117676	0.1745341485463971	[319]	[408,284,413,629]	2	hSpCas9	negative selection	6966264
26553483	26553506	1	-	27260156	G402	viability	TCACTCACTTCTCAGGCTTGAGG	RPS6KA1	ENSG00000117676	0.05540203270919741	[931]	[1463,1411,1109,808]	0	hSpCas9	negative selection	6966265
26551684	26551707	1	-	27260156	L33	viability	TGAAGAGGTCCCCACCACGCAGG	RPS6KA1	ENSG00000117676	-0.3115275733111125	[435]	[299,137,249,371]	-6	hSpCas9	negative selection	7023261
26536948	26536971	1	+	27260156	L33	viability	AGCTGGACTTCAGCCGTCCAAGG	RPS6KA1	ENSG00000117676	0.1500998563277554	[545]	[482,275,433,579]	3	hSpCas9	negative selection	7023262
26551670	26551693	1	+	27260156	L33	viability	CTCATTCTGGACTTCCTGCGTGG	RPS6KA1	ENSG00000117676	-0.29898649242624176	[416]	[361,115,203,384]	-6	hSpCas9	negative selection	7023263
26536919	26536942	1	+	27260156	L33	viability	TTCCAGAATGGACAGACCTCAGG	RPS6KA1	ENSG00000117676	-0.28166600199567415	[714]	[623,261,333,556]	-6	hSpCas9	negative selection	7087514
26553453	26553476	1	-	27260156	L33	viability	AAATGATACCCAGGCTGTGCAGG	RPS6KA1	ENSG00000117676	-0.16963777985983963	[319]	[211,106,155,416]	-4	hSpCas9	negative selection	7087515
26553483	26553506	1	-	27260156	L33	viability	TCACTCACTTCTCAGGCTTGAGG	RPS6KA1	ENSG00000117676	0.03458692848730316	[931]	[827,496,601,823]	0	hSpCas9	negative selection	7087516
26551684	26551707	1	-	27260156	K562	viability	TGAAGAGGTCCCCACCACGCAGG	RPS6KA1	ENSG00000117676	0.05911367349660609	[435]	[358,291,393,539]	0	hSpCas9	negative selection	7144512
26536948	26536971	1	+	27260156	K562	viability	AGCTGGACTTCAGCCGTCCAAGG	RPS6KA1	ENSG00000117676	0.7800438668330723	[545]	[735,1175,356,1040]	8	hSpCas9	negative selection	7144513
26551670	26551693	1	+	27260156	K562	viability	CTCATTCTGGACTTCCTGCGTGG	RPS6KA1	ENSG00000117676	0.2608847302329015	[416]	[644,430,356,363]	3	hSpCas9	negative selection	7144514
26536919	26536942	1	+	27260156	K562	viability	TTCCAGAATGGACAGACCTCAGG	RPS6KA1	ENSG00000117676	0.09646104882999029	[714]	[1154,852,573,229]	1	hSpCas9	negative selection	7208765
26553453	26553476	1	-	27260156	K562	viability	AAATGATACCCAGGCTGTGCAGG	RPS6KA1	ENSG00000117676	0.3153624424492151	[319]	[307,632,270,225]	4	hSpCas9	negative selection	7208766
26553483	26553506	1	-	27260156	K562	viability	TCACTCACTTCTCAGGCTTGAGG	RPS6KA1	ENSG00000117676	-0.13595824722472338	[931]	[989,671,930,463]	-2	hSpCas9	negative selection	7208767
26551684	26551707	1	-	27260156	HT29	viability	TGAAGAGGTCCCCACCACGCAGG	RPS6KA1	ENSG00000117676	0.3072615081221233	[435]	[680,807,717,451]	6	hSpCas9	negative selection	7265763
26536948	26536971	1	+	27260156	HT29	viability	AGCTGGACTTCAGCCGTCCAAGG	RPS6KA1	ENSG00000117676	0.41258474762028885	[545]	[762,1189,739,854]	7	hSpCas9	negative selection	7265764
26551670	26551693	1	+	27260156	HT29	viability	CTCATTCTGGACTTCCTGCGTGG	RPS6KA1	ENSG00000117676	0.41856953508242617	[416]	[868,660,685,521]	7	hSpCas9	negative selection	7265765
26536919	26536942	1	+	27260156	HT29	viability	TTCCAGAATGGACAGACCTCAGG	RPS6KA1	ENSG00000117676	0.22257680174526295	[714]	[911,1102,1324,742]	4	hSpCas9	negative selection	7330016
26553453	26553476	1	-	27260156	HT29	viability	AAATGATACCCAGGCTGTGCAGG	RPS6KA1	ENSG00000117676	0.30922210768318154	[319]	[406,533,552,434]	6	hSpCas9	negative selection	7330017
26553483	26553506	1	-	27260156	HT29	viability	TCACTCACTTCTCAGGCTTGAGG	RPS6KA1	ENSG00000117676	0.29096076263971293	[931]	[1556,1513,1267,1237]	6	hSpCas9	negative selection	7330018
26551684	26551707	1	-	27260156	MHHES1	viability	TGAAGAGGTCCCCACCACGCAGG	RPS6KA1	ENSG00000117676	-0.0568635485893037	[435]	[577,694,389,291]	-1	hSpCas9	negative selection	7387014
26536948	26536971	1	+	27260156	MHHES1	viability	AGCTGGACTTCAGCCGTCCAAGG	RPS6KA1	ENSG00000117676	0.5307551602880676	[545]	[797,966,821,931]	8	hSpCas9	negative selection	7387015
26551670	26551693	1	+	27260156	MHHES1	viability	CTCATTCTGGACTTCCTGCGTGG	RPS6KA1	ENSG00000117676	0.202759846951329	[416]	[727,374,510,540]	4	hSpCas9	negative selection	7387016
26536919	26536942	1	+	27260156	MHHES1	viability	TTCCAGAATGGACAGACCTCAGG	RPS6KA1	ENSG00000117676	-0.01587888755474276	[714]	[933,948,808,562]	0	hSpCas9	negative selection	7451267
26553453	26553476	1	-	27260156	MHHES1	viability	AAATGATACCCAGGCTGTGCAGG	RPS6KA1	ENSG00000117676	-0.3305685635021519	[319]	[299,348,316,201]	-6	hSpCas9	negative selection	7451268
26553483	26553506	1	-	27260156	MHHES1	viability	TCACTCACTTCTCAGGCTTGAGG	RPS6KA1	ENSG00000117676	0.23650079513685995	[931]	[1337,1500,1331,872]	4	hSpCas9	negative selection	7451269
26551684	26551707	1	-	27260156	MEWO	viability	TGAAGAGGTCCCCACCACGCAGG	RPS6KA1	ENSG00000117676	0.27968996676425606	[435]	[544,505,443]	6	hSpCas9	negative selection	7508265
26536948	26536971	1	+	27260156	MEWO	viability	AGCTGGACTTCAGCCGTCCAAGG	RPS6KA1	ENSG00000117676	-0.041755831322649706	[545]	[696,396,433]	-1	hSpCas9	negative selection	7508266
26551670	26551693	1	+	27260156	MEWO	viability	CTCATTCTGGACTTCCTGCGTGG	RPS6KA1	ENSG00000117676	0.18205280769157375	[416]	[659,405,303]	4	hSpCas9	negative selection	7508267
26536919	26536942	1	+	27260156	MEWO	viability	TTCCAGAATGGACAGACCTCAGG	RPS6KA1	ENSG00000117676	0.00449053651523601	[714]	[872,469,709]	0	hSpCas9	negative selection	7572518
26553453	26553476	1	-	27260156	MEWO	viability	AAATGATACCCAGGCTGTGCAGG	RPS6KA1	ENSG00000117676	-0.3027527779500223	[319]	[305,310,122]	-6	hSpCas9	negative selection	7572519
26553483	26553506	1	-	27260156	MEWO	viability	TCACTCACTTCTCAGGCTTGAGG	RPS6KA1	ENSG00000117676	0.12016317013526245	[931]	[1083,790,994]	2	hSpCas9	negative selection	7572520
26551684	26551707	1	-	27260156	LNCAPCLONEFGC	viability	TGAAGAGGTCCCCACCACGCAGG	RPS6KA1	ENSG00000117676	0.6199730468451592	[435]	[632,540,590,663]	8	hSpCas9	negative selection	7629516
26536948	26536971	1	+	27260156	LNCAPCLONEFGC	viability	AGCTGGACTTCAGCCGTCCAAGG	RPS6KA1	ENSG00000117676	0.6135374504493348	[545]	[852,671,694,800]	8	hSpCas9	negative selection	7629517
26551670	26551693	1	+	27260156	LNCAPCLONEFGC	viability	CTCATTCTGGACTTCCTGCGTGG	RPS6KA1	ENSG00000117676	0.6253860026641742	[416]	[348,624,796,592]	8	hSpCas9	negative selection	7629518
26536919	26536942	1	+	27260156	LNCAPCLONEFGC	viability	TTCCAGAATGGACAGACCTCAGG	RPS6KA1	ENSG00000117676	0.2041812520046109	[714]	[749,460,948,872]	3	hSpCas9	negative selection	7693769
26553453	26553476	1	-	27260156	LNCAPCLONEFGC	viability	AAATGATACCCAGGCTGTGCAGG	RPS6KA1	ENSG00000117676	-0.14693327639141218	[319]	[184,321,311,232]	-2	hSpCas9	negative selection	7693770
26553483	26553506	1	-	27260156	LNCAPCLONEFGC	viability	TCACTCACTTCTCAGGCTTGAGG	RPS6KA1	ENSG00000117676	0.311906350423239	[931]	[1187,782,1356,923]	5	hSpCas9	negative selection	7693771
26551684	26551707	1	-	27260156	PANC0327	viability	TGAAGAGGTCCCCACCACGCAGG	RPS6KA1	ENSG00000117676	0.41282807395810406	[435]	[571,535,372,582]	6	hSpCas9	negative selection	7750767
26536948	26536971	1	+	27260156	PANC0327	viability	AGCTGGACTTCAGCCGTCCAAGG	RPS6KA1	ENSG00000117676	0.263762546708399	[545]	[384,517,568,848]	4	hSpCas9	negative selection	7750768
26551670	26551693	1	+	27260156	PANC0327	viability	CTCATTCTGGACTTCCTGCGTGG	RPS6KA1	ENSG00000117676	0.06978111446602406	[416]	[439,437,420,253]	1	hSpCas9	negative selection	7750769
26536919	26536942	1	+	27260156	PANC0327	viability	TTCCAGAATGGACAGACCTCAGG	RPS6KA1	ENSG00000117676	0.17909028006796324	[714]	[703,926,634,581]	2	hSpCas9	negative selection	7815020
26553453	26553476	1	-	27260156	PANC0327	viability	AAATGATACCCAGGCTGTGCAGG	RPS6KA1	ENSG00000117676	-0.10121590238157196	[319]	[273,161,315,321]	-1	hSpCas9	negative selection	7815021
26553483	26553506	1	-	27260156	PANC0327	viability	TCACTCACTTCTCAGGCTTGAGG	RPS6KA1	ENSG00000117676	0.2574738630215	[931]	[1032,916,1304,716]	4	hSpCas9	negative selection	7815022
26551684	26551707	1	-	27260156	NCIH2009	viability	TGAAGAGGTCCCCACCACGCAGG	RPS6KA1	ENSG00000117676	0.26881458447938467	[435]	[770,505,934]	3	hSpCas9	negative selection	7872018
26536948	26536971	1	+	27260156	NCIH2009	viability	AGCTGGACTTCAGCCGTCCAAGG	RPS6KA1	ENSG00000117676	0.3375598512574265	[545]	[1025,1044,829]	4	hSpCas9	negative selection	7872019
26551670	26551693	1	+	27260156	NCIH2009	viability	CTCATTCTGGACTTCCTGCGTGG	RPS6KA1	ENSG00000117676	-0.21110839673611648	[416]	[513,567,427]	-3	hSpCas9	negative selection	7872020
26536919	26536942	1	+	27260156	NCIH2009	viability	TTCCAGAATGGACAGACCTCAGG	RPS6KA1	ENSG00000117676	-0.29124131333896786	[714]	[1030,766,692]	-4	hSpCas9	negative selection	7936271
26553453	26553476	1	-	27260156	NCIH2009	viability	AAATGATACCCAGGCTGTGCAGG	RPS6KA1	ENSG00000117676	-0.02963578846972237	[319]	[560,303,474]	0	hSpCas9	negative selection	7936272
26553483	26553506	1	-	27260156	NCIH2009	viability	TCACTCACTTCTCAGGCTTGAGG	RPS6KA1	ENSG00000117676	-0.10389347504604651	[931]	[1266,1040,1338]	-1	hSpCas9	negative selection	7936273
26551684	26551707	1	-	27260156	NCIH1373	viability	TGAAGAGGTCCCCACCACGCAGG	RPS6KA1	ENSG00000117676	0.5890989090861501	[435]	[695,634,802,212]	6	hSpCas9	negative selection	7993269
26536948	26536971	1	+	27260156	NCIH1373	viability	AGCTGGACTTCAGCCGTCCAAGG	RPS6KA1	ENSG00000117676	0.3749142171761183	[545]	[1481,446,661,189]	3	hSpCas9	negative selection	7993270
26551670	26551693	1	+	27260156	NCIH1373	viability	CTCATTCTGGACTTCCTGCGTGG	RPS6KA1	ENSG00000117676	-0.2885070398471753	[416]	[532,348,371,77]	-3	hSpCas9	negative selection	7993271
26536919	26536942	1	+	27260156	NCIH1373	viability	TTCCAGAATGGACAGACCTCAGG	RPS6KA1	ENSG00000117676	0.01331800874879252	[714]	[717,1253,495,183]	0	hSpCas9	negative selection	8057522
26553453	26553476	1	-	27260156	NCIH1373	viability	AAATGATACCCAGGCTGTGCAGG	RPS6KA1	ENSG00000117676	-0.7932417794120499	[319]	[114,127,256,85]	-7	hSpCas9	negative selection	8057523
26553483	26553506	1	-	27260156	NCIH1373	viability	TCACTCACTTCTCAGGCTTGAGG	RPS6KA1	ENSG00000117676	-0.6051693666418406	[931]	[632,510,499,299]	-6	hSpCas9	negative selection	8057524
26551684	26551707	1	-	27260156	PATU8902	viability	TGAAGAGGTCCCCACCACGCAGG	RPS6KA1	ENSG00000117676	0.8822937657795259	[435]	[1086,1122,1265,931]	8	hSpCas9	negative selection	8114520
26536948	26536971	1	+	27260156	PATU8902	viability	AGCTGGACTTCAGCCGTCCAAGG	RPS6KA1	ENSG00000117676	0.8558710475745378	[545]	[1367,1403,1215,1570]	8	hSpCas9	negative selection	8114521
26551670	26551693	1	+	27260156	PATU8902	viability	CTCATTCTGGACTTCCTGCGTGG	RPS6KA1	ENSG00000117676	0.5563136527197263	[416]	[810,974,785,855]	6	hSpCas9	negative selection	8114522
26536919	26536942	1	+	27260156	PATU8902	viability	TTCCAGAATGGACAGACCTCAGG	RPS6KA1	ENSG00000117676	-0.10045586287605279	[714]	[776,1143,731,1132]	-1	hSpCas9	negative selection	8178773
26553453	26553476	1	-	27260156	PATU8902	viability	AAATGATACCCAGGCTGTGCAGG	RPS6KA1	ENSG00000117676	0.27787737238670346	[319]	[410,383,485,938]	3	hSpCas9	negative selection	8178774
26553483	26553506	1	-	27260156	PATU8902	viability	TCACTCACTTCTCAGGCTTGAGG	RPS6KA1	ENSG00000117676	0.6198115391252185	[931]	[2531,2628,1342,1571]	6	hSpCas9	negative selection	8178775
26551684	26551707	1	-	27260156	PANC1	viability	TGAAGAGGTCCCCACCACGCAGG	RPS6KA1	ENSG00000117676	0.06503596240624339	[435]	[390,457,401,332]	1	hSpCas9	negative selection	8235771
26536948	26536971	1	+	27260156	PANC1	viability	AGCTGGACTTCAGCCGTCCAAGG	RPS6KA1	ENSG00000117676	0.28677676501984883	[545]	[781,719,401,423]	4	hSpCas9	negative selection	8235772
26551670	26551693	1	+	27260156	PANC1	viability	CTCATTCTGGACTTCCTGCGTGG	RPS6KA1	ENSG00000117676	0.13086463455559327	[416]	[378,619,310,311]	2	hSpCas9	negative selection	8235773
26536919	26536942	1	+	27260156	PANC1	viability	TTCCAGAATGGACAGACCTCAGG	RPS6KA1	ENSG00000117676	-0.13612776905619117	[714]	[485,625,772,386]	-2	hSpCas9	negative selection	8300024
26553453	26553476	1	-	27260156	PANC1	viability	AAATGATACCCAGGCTGTGCAGG	RPS6KA1	ENSG00000117676	-0.4570362560538346	[319]	[108,334,221,166]	-6	hSpCas9	negative selection	8300025
26553483	26553506	1	-	27260156	PANC1	viability	TCACTCACTTCTCAGGCTTGAGG	RPS6KA1	ENSG00000117676	0.03647734688923243	[931]	[767,1347,885,441]	0	hSpCas9	negative selection	8300026
26551684	26551707	1	-	27260156	PANC0813	viability	TGAAGAGGTCCCCACCACGCAGG	RPS6KA1	ENSG00000117676	0.23777758061951682	[435]	[803,494,549,584]	4	hSpCas9	negative selection	8357022
26536948	26536971	1	+	27260156	PANC0813	viability	AGCTGGACTTCAGCCGTCCAAGG	RPS6KA1	ENSG00000117676	0.38982525181462546	[545]	[988,730,768,881]	6	hSpCas9	negative selection	8357023
26551670	26551693	1	+	27260156	PANC0813	viability	CTCATTCTGGACTTCCTGCGTGG	RPS6KA1	ENSG00000117676	0.06255678800800324	[416]	[481,521,344,682]	1	hSpCas9	negative selection	8357024
26536919	26536942	1	+	27260156	PANC0813	viability	TTCCAGAATGGACAGACCTCAGG	RPS6KA1	ENSG00000117676	-0.23833147081336775	[714]	[889,823,696,465]	-4	hSpCas9	negative selection	8421275
26553453	26553476	1	-	27260156	PANC0813	viability	AAATGATACCCAGGCTGTGCAGG	RPS6KA1	ENSG00000117676	-0.07360140887157607	[319]	[300,287,552,285]	-1	hSpCas9	negative selection	8421276
26553483	26553506	1	-	27260156	PANC0813	viability	TCACTCACTTCTCAGGCTTGAGG	RPS6KA1	ENSG00000117676	0.10095491971069925	[931]	[1540,1139,1197,866]	1	hSpCas9	negative selection	8421277
26551684	26551707	1	-	27260156	RDES	viability	TGAAGAGGTCCCCACCACGCAGG	RPS6KA1	ENSG00000117676	0.5195987351038935	[435]	[587,729,832,735]	8	hSpCas9	negative selection	8478273
26536948	26536971	1	+	27260156	RDES	viability	AGCTGGACTTCAGCCGTCCAAGG	RPS6KA1	ENSG00000117676	0.43058600814183157	[545]	[633,809,951,1048]	7	hSpCas9	negative selection	8478274
26551670	26551693	1	+	27260156	RDES	viability	CTCATTCTGGACTTCCTGCGTGG	RPS6KA1	ENSG00000117676	0.21087611363331454	[416]	[482,469,498,811]	3	hSpCas9	negative selection	8478275
26536919	26536942	1	+	27260156	RDES	viability	TTCCAGAATGGACAGACCTCAGG	RPS6KA1	ENSG00000117676	0.02285670137282947	[714]	[763,932,757,865]	0	hSpCas9	negative selection	8542526
26553453	26553476	1	-	27260156	RDES	viability	AAATGATACCCAGGCTGTGCAGG	RPS6KA1	ENSG00000117676	0.09563338650408026	[319]	[295,433,387,471]	1	hSpCas9	negative selection	8542527
26553483	26553506	1	-	27260156	RDES	viability	TCACTCACTTCTCAGGCTTGAGG	RPS6KA1	ENSG00000117676	0.003631430039823247	[931]	[831,980,1127,1445]	0	hSpCas9	negative selection	8542528
26551684	26551707	1	-	27260156	PC3	viability	TGAAGAGGTCCCCACCACGCAGG	RPS6KA1	ENSG00000117676	0.36725177407041315	[435]	[276,510,978,728]	7	hSpCas9	negative selection	8599524
26536948	26536971	1	+	27260156	PC3	viability	AGCTGGACTTCAGCCGTCCAAGG	RPS6KA1	ENSG00000117676	0.26463397512229975	[545]	[324,615,1307,718]	6	hSpCas9	negative selection	8599525
26551670	26551693	1	+	27260156	PC3	viability	CTCATTCTGGACTTCCTGCGTGG	RPS6KA1	ENSG00000117676	0.5204942731317366	[416]	[335,443,1147,749]	9	hSpCas9	negative selection	8599526
26536919	26536942	1	+	27260156	PC3	viability	TTCCAGAATGGACAGACCTCAGG	RPS6KA1	ENSG00000117676	0.03768594472335074	[714]	[371,690,1547,734]	0	hSpCas9	negative selection	8663777
26553453	26553476	1	-	27260156	PC3	viability	AAATGATACCCAGGCTGTGCAGG	RPS6KA1	ENSG00000117676	0.05188894009099421	[319]	[225,357,593,252]	1	hSpCas9	negative selection	8663778
26553483	26553506	1	-	27260156	PC3	viability	TCACTCACTTCTCAGGCTTGAGG	RPS6KA1	ENSG00000117676	0.24327118410081894	[931]	[728,844,2026,1230]	5	hSpCas9	negative selection	8663779
26551684	26551707	1	-	27260156	PATU8988T	viability	TGAAGAGGTCCCCACCACGCAGG	RPS6KA1	ENSG00000117676	0.5649279819826754	[435]	[650,640,502,707]	8	hSpCas9	negative selection	8720775
26536948	26536971	1	+	27260156	PATU8988T	viability	AGCTGGACTTCAGCCGTCCAAGG	RPS6KA1	ENSG00000117676	0.2046779995629034	[545]	[833,557,583,437]	3	hSpCas9	negative selection	8720776
26551670	26551693	1	+	27260156	PATU8988T	viability	CTCATTCTGGACTTCCTGCGTGG	RPS6KA1	ENSG00000117676	0.001616805623414208	[416]	[342,431,375,470]	0	hSpCas9	negative selection	8720777
26536919	26536942	1	+	27260156	PATU8988T	viability	TTCCAGAATGGACAGACCTCAGG	RPS6KA1	ENSG00000117676	-0.035813598002709335	[714]	[645,741,694,613]	0	hSpCas9	negative selection	8785028
26553453	26553476	1	-	27260156	PATU8988T	viability	AAATGATACCCAGGCTGTGCAGG	RPS6KA1	ENSG00000117676	-0.11648660131474853	[319]	[284,270,242,345]	-2	hSpCas9	negative selection	8785029
26553483	26553506	1	-	27260156	PATU8988T	viability	TCACTCACTTCTCAGGCTTGAGG	RPS6KA1	ENSG00000117676	-0.15668539595291375	[931]	[728,840,727,948]	-3	hSpCas9	negative selection	8785030
26551684	26551707	1	-	27260156	T47D	viability	TGAAGAGGTCCCCACCACGCAGG	RPS6KA1	ENSG00000117676	0.28264940957375034	[435]	[716,699,501,544]	6	hSpCas9	negative selection	8842026
26536948	26536971	1	+	27260156	T47D	viability	AGCTGGACTTCAGCCGTCCAAGG	RPS6KA1	ENSG00000117676	0.22674996755718174	[545]	[741,642,675,931]	5	hSpCas9	negative selection	8842027
26551670	26551693	1	+	27260156	T47D	viability	CTCATTCTGGACTTCCTGCGTGG	RPS6KA1	ENSG00000117676	0.1618592191958363	[416]	[544,465,506,666]	3	hSpCas9	negative selection	8842028
26536919	26536942	1	+	27260156	T47D	viability	TTCCAGAATGGACAGACCTCAGG	RPS6KA1	ENSG00000117676	-0.007367088067948946	[714]	[758,757,793,1015]	0	hSpCas9	negative selection	8906279
26553453	26553476	1	-	27260156	T47D	viability	AAATGATACCCAGGCTGTGCAGG	RPS6KA1	ENSG00000117676	-0.023516155296095964	[319]	[341,378,389,353]	0	hSpCas9	negative selection	8906280
26553483	26553506	1	-	27260156	T47D	viability	TCACTCACTTCTCAGGCTTGAGG	RPS6KA1	ENSG00000117676	0.007971950293627406	[931]	[1097,1058,1042,1172]	0	hSpCas9	negative selection	8906281
26551684	26551707	1	-	27260156	SU8686	viability	TGAAGAGGTCCCCACCACGCAGG	RPS6KA1	ENSG00000117676	0.19950817863779474	[435]	[497,348,558,615]	3	hSpCas9	negative selection	8963277
26536948	26536971	1	+	27260156	SU8686	viability	AGCTGGACTTCAGCCGTCCAAGG	RPS6KA1	ENSG00000117676	0.2576416892743951	[545]	[634,676,574,700]	4	hSpCas9	negative selection	8963278
26551670	26551693	1	+	27260156	SU8686	viability	CTCATTCTGGACTTCCTGCGTGG	RPS6KA1	ENSG00000117676	-0.04405923621488328	[416]	[296,410,383,541]	-1	hSpCas9	negative selection	8963279
26536919	26536942	1	+	27260156	SU8686	viability	TTCCAGAATGGACAGACCTCAGG	RPS6KA1	ENSG00000117676	-0.33288059304243556	[714]	[459,569,423,845]	-5	hSpCas9	negative selection	9027530
26553453	26553476	1	-	27260156	SU8686	viability	AAATGATACCCAGGCTGTGCAGG	RPS6KA1	ENSG00000117676	-0.19678178391110823	[319]	[368,180,237,325]	-3	hSpCas9	negative selection	9027531
26553483	26553506	1	-	27260156	SU8686	viability	TCACTCACTTCTCAGGCTTGAGG	RPS6KA1	ENSG00000117676	0.1354564918331037	[931]	[898,972,1044,1181]	2	hSpCas9	negative selection	9027532
26551684	26551707	1	-	27260156	SKES1	viability	TGAAGAGGTCCCCACCACGCAGG	RPS6KA1	ENSG00000117676	0.3757368582435125	[435]	[574,505,711,462]	7	hSpCas9	negative selection	9084528
26536948	26536971	1	+	27260156	SKES1	viability	AGCTGGACTTCAGCCGTCCAAGG	RPS6KA1	ENSG00000117676	0.11733414365869355	[545]	[689,559,580,541]	2	hSpCas9	negative selection	9084529
26551670	26551693	1	+	27260156	SKES1	viability	CTCATTCTGGACTTCCTGCGTGG	RPS6KA1	ENSG00000117676	0.09586062769977603	[416]	[606,446,421,333]	2	hSpCas9	negative selection	9084530
26536919	26536942	1	+	27260156	SKES1	viability	TTCCAGAATGGACAGACCTCAGG	RPS6KA1	ENSG00000117676	0.0644396294375289	[714]	[958,600,668,757]	1	hSpCas9	negative selection	9148781
26553453	26553476	1	-	27260156	SKES1	viability	AAATGATACCCAGGCTGTGCAGG	RPS6KA1	ENSG00000117676	-0.11200193018108984	[319]	[546,315,196,171]	-2	hSpCas9	negative selection	9148782
26553483	26553506	1	-	27260156	SKES1	viability	TCACTCACTTCTCAGGCTTGAGG	RPS6KA1	ENSG00000117676	0.2226511154616767	[931]	[1203,1224,1085,871]	5	hSpCas9	negative selection	9148783
26551684	26551707	1	-	27260156	TOV112D	viability	TGAAGAGGTCCCCACCACGCAGG	RPS6KA1	ENSG00000117676	0.2950101707049353	[435]	[547,846,478,350]	5	hSpCas9	negative selection	9205779
26536948	26536971	1	+	27260156	TOV112D	viability	AGCTGGACTTCAGCCGTCCAAGG	RPS6KA1	ENSG00000117676	0.3722907767722522	[545]	[645,632,762,762]	7	hSpCas9	negative selection	9205780
26551670	26551693	1	+	27260156	TOV112D	viability	CTCATTCTGGACTTCCTGCGTGG	RPS6KA1	ENSG00000117676	0.282287548154171	[416]	[321,634,493,592]	5	hSpCas9	negative selection	9205781
26536919	26536942	1	+	27260156	TOV112D	viability	TTCCAGAATGGACAGACCTCAGG	RPS6KA1	ENSG00000117676	-0.045696572923855316	[714]	[552,828,958,460]	-1	hSpCas9	negative selection	9270032
26553453	26553476	1	-	27260156	TOV112D	viability	AAATGATACCCAGGCTGTGCAGG	RPS6KA1	ENSG00000117676	0.044429185421767436	[319]	[354,317,225,418]	0	hSpCas9	negative selection	9270033
26553483	26553506	1	-	27260156	TOV112D	viability	TCACTCACTTCTCAGGCTTGAGG	RPS6KA1	ENSG00000117676	-0.02671045178351028	[931]	[667,1604,791,751]	0	hSpCas9	negative selection	9270034
26551684	26551707	1	-	27260156	TC71	viability	TGAAGAGGTCCCCACCACGCAGG	RPS6KA1	ENSG00000117676	0.3299777632790927	[435]	[473,593,612,675]	7	hSpCas9	negative selection	9327030
26536948	26536971	1	+	27260156	TC71	viability	AGCTGGACTTCAGCCGTCCAAGG	RPS6KA1	ENSG00000117676	0.1066938248426057	[545]	[595,666,663,590]	2	hSpCas9	negative selection	9327031
26551670	26551693	1	+	27260156	TC71	viability	CTCATTCTGGACTTCCTGCGTGG	RPS6KA1	ENSG00000117676	0.184584283670435	[416]	[406,486,511,635]	4	hSpCas9	negative selection	9327032
26536919	26536942	1	+	27260156	TC71	viability	TTCCAGAATGGACAGACCTCAGG	RPS6KA1	ENSG00000117676	0.047120388636904154	[714]	[842,753,725,848]	1	hSpCas9	negative selection	9391283
26553453	26553476	1	-	27260156	TC71	viability	AAATGATACCCAGGCTGTGCAGG	RPS6KA1	ENSG00000117676	-0.09678705827169953	[319]	[269,348,297,370]	-2	hSpCas9	negative selection	9391284
26553483	26553506	1	-	27260156	TC71	viability	TCACTCACTTCTCAGGCTTGAGG	RPS6KA1	ENSG00000117676	0.1629080074557906	[931]	[1129,1033,1369,918]	4	hSpCas9	negative selection	9391285
26551684	26551707	1	-	27260156	TC32	viability	TGAAGAGGTCCCCACCACGCAGG	RPS6KA1	ENSG00000117676	0.33981970510847015	[435]	[498,284,835,574]	6	hSpCas9	negative selection	9448281
26536948	26536971	1	+	27260156	TC32	viability	AGCTGGACTTCAGCCGTCCAAGG	RPS6KA1	ENSG00000117676	0.4442196814125451	[545]	[531,499,1184,717]	7	hSpCas9	negative selection	9448282
26551670	26551693	1	+	27260156	TC32	viability	CTCATTCTGGACTTCCTGCGTGG	RPS6KA1	ENSG00000117676	0.11274547075514874	[416]	[517,266,403,529]	2	hSpCas9	negative selection	9448283
26536919	26536942	1	+	27260156	TC32	viability	TTCCAGAATGGACAGACCTCAGG	RPS6KA1	ENSG00000117676	0.12207888248654852	[714]	[565,674,915,800]	2	hSpCas9	negative selection	9512534
26553453	26553476	1	-	27260156	TC32	viability	AAATGATACCCAGGCTGTGCAGG	RPS6KA1	ENSG00000117676	-0.025365149517813323	[319]	[296,183,423,325]	0	hSpCas9	negative selection	9512535
26553483	26553506	1	-	27260156	TC32	viability	TCACTCACTTCTCAGGCTTGAGG	RPS6KA1	ENSG00000117676	0.2899093273947623	[931]	[986,676,1146,1614]	5	hSpCas9	negative selection	9512536
26529946	26529969	1	-	27869803	HPAFII	viability after 27 days	CACTAGCTCCATGAGCGGCCAGG	RPS6KA1	ENSG00000117676	-0.25956444518960375	[135]	[32,81,NaN]	-2	hSpCas9	negative selection	9533432
26543207	26543230	1	-	27869803	HPAFII	viability after 27 days	CTGCTCACCTTTCTGGGACAGGG	RPS6KA1	ENSG00000117676	0.13325872161693764	[565]	[381,279,NaN]	1	hSpCas9	negative selection	9533433
26544153	26544176	1	-	27869803	HPAFII	viability after 27 days	GGGCAGATAGGTCTGACACCTGG	RPS6KA1	ENSG00000117676	0.821103826246393	[68]	[8,109,NaN]	6	hSpCas9	negative selection	9533434
26546023	26546046	1	-	27869803	HPAFII	viability after 27 days	GCACACTCACCGAGTCCCGCTGG	RPS6KA1	ENSG00000117676	-0.10839884272986322	[202]	[164,43,NaN]	-1	hSpCas9	negative selection	9533435
26546894	26546917	1	+	27869803	HPAFII	viability after 27 days	ATCACGCACCACGTCAAGGCTGG	RPS6KA1	ENSG00000117676	-0.6320153261870258	[245]	[137,37,NaN]	-4	hSpCas9	negative selection	9533436
26551404	26551427	1	-	27869803	HPAFII	viability after 27 days	TCTCCATCTTGGTCCGGACGCGG	RPS6KA1	ENSG00000117676	1.4810603201085566	[145]	[348,101,NaN]	9	hSpCas9	negative selection	9533437
26529946	26529969	1	-	27869803	HPAFII	viability after 15 days	CACTAGCTCCATGAGCGGCCAGG	RPS6KA1	ENSG00000117676	0.3737827209461597	[135]	[263,142,NaN]	4	hSpCas9	negative selection	9615881
26543207	26543230	1	-	27869803	HPAFII	viability after 15 days	CTGCTCACCTTTCTGGGACAGGG	RPS6KA1	ENSG00000117676	0.12838250861845002	[565]	[942,491,NaN]	1	hSpCas9	negative selection	9615882
26544153	26544176	1	-	27869803	HPAFII	viability after 15 days	GGGCAGATAGGTCTGACACCTGG	RPS6KA1	ENSG00000117676	0.9505241222749747	[68]	[101,168,NaN]	9	hSpCas9	negative selection	9615883
26546023	26546046	1	-	27869803	HPAFII	viability after 15 days	GCACACTCACCGAGTCCCGCTGG	RPS6KA1	ENSG00000117676	0.052322949231256854	[202]	[343,152,NaN]	0	hSpCas9	negative selection	9615884
26546894	26546917	1	+	27869803	HPAFII	viability after 15 days	ATCACGCACCACGTCAAGGCTGG	RPS6KA1	ENSG00000117676	-0.07255061895644346	[245]	[428,140,NaN]	-1	hSpCas9	negative selection	9615885
26551404	26551427	1	-	27869803	HPAFII	viability after 15 days	TCTCCATCTTGGTCCGGACGCGG	RPS6KA1	ENSG00000117676	0.4591756934489299	[145]	[359,125,NaN]	5	hSpCas9	negative selection	9615886
26529946	26529969	1	-	27869803	ASPC1	viability after 36 days	CACTAGCTCCATGAGCGGCCAGG	RPS6KA1	ENSG00000117676	0.4424925202641864	[281]	[38,251,104]	4	hSpCas9	negative selection	9698330
26543207	26543230	1	-	27869803	ASPC1	viability after 36 days	CTGCTCACCTTTCTGGGACAGGG	RPS6KA1	ENSG00000117676	-0.6585870174403917	[1651]	[320,588,214]	-6	hSpCas9	negative selection	9698331
26544153	26544176	1	-	27869803	ASPC1	viability after 36 days	GGGCAGATAGGTCTGACACCTGG	RPS6KA1	ENSG00000117676	-2.0340191263021157	[240]	[0,41,16]	-9	hSpCas9	negative selection	9698332
26546023	26546046	1	-	27869803	ASPC1	viability after 36 days	GCACACTCACCGAGTCCCGCTGG	RPS6KA1	ENSG00000117676	-0.4080044801804329	[655]	[78,157,247]	-4	hSpCas9	negative selection	9698333
26546894	26546917	1	+	27869803	ASPC1	viability after 36 days	ATCACGCACCACGTCAAGGCTGG	RPS6KA1	ENSG00000117676	-0.27817121134036915	[766]	[308,218,157]	-3	hSpCas9	negative selection	9698334
26551404	26551427	1	-	27869803	ASPC1	viability after 36 days	TCTCCATCTTGGTCCGGACGCGG	RPS6KA1	ENSG00000117676	-0.7058086314961112	[465]	[6,111,153]	-6	hSpCas9	negative selection	9698335
26529946	26529969	1	-	27869803	PATU8988S	viability after 35 days	CACTAGCTCCATGAGCGGCCAGG	RPS6KA1	ENSG00000117676	0.6031421957231304	[316]	[165,221,NaN]	6	hSpCas9	negative selection	9780779
26543207	26543230	1	-	27869803	PATU8988S	viability after 35 days	CTGCTCACCTTTCTGGGACAGGG	RPS6KA1	ENSG00000117676	0.13648051006117923	[1421]	[863,393,NaN]	1	hSpCas9	negative selection	9780780
26544153	26544176	1	-	27869803	PATU8988S	viability after 35 days	GGGCAGATAGGTCTGACACCTGG	RPS6KA1	ENSG00000117676	1.6179347701883235	[208]	[416,98,NaN]	9	hSpCas9	negative selection	9780781
26546023	26546046	1	-	27869803	PATU8988S	viability after 35 days	GCACACTCACCGAGTCCCGCTGG	RPS6KA1	ENSG00000117676	-0.781667451569731	[518]	[160,81,NaN]	-6	hSpCas9	negative selection	9780782
26546894	26546917	1	+	27869803	PATU8988S	viability after 35 days	ATCACGCACCACGTCAAGGCTGG	RPS6KA1	ENSG00000117676	-0.4414117802991564	[599]	[157,197,NaN]	-4	hSpCas9	negative selection	9780783
26551404	26551427	1	-	27869803	PATU8988S	viability after 35 days	TCTCCATCTTGGTCCGGACGCGG	RPS6KA1	ENSG00000117676	0.9456043773323157	[397]	[407,208,NaN]	8	hSpCas9	negative selection	9780784
26529946	26529969	1	-	27869803	PATU8988S	viability after 31 days	CACTAGCTCCATGAGCGGCCAGG	RPS6KA1	ENSG00000117676	0.23223798434035103	[316]	[140,157,NaN]	3	hSpCas9	negative selection	9863228
26543207	26543230	1	-	27869803	PATU8988S	viability after 31 days	CTGCTCACCTTTCTGGGACAGGG	RPS6KA1	ENSG00000117676	-0.298729163807405	[1421]	[478,437,NaN]	-3	hSpCas9	negative selection	9863229
26544153	26544176	1	-	27869803	PATU8988S	viability after 31 days	GGGCAGATAGGTCTGACACCTGG	RPS6KA1	ENSG00000117676	1.40502567958591	[208]	[298,120,NaN]	9	hSpCas9	negative selection	9863230
26546023	26546046	1	-	27869803	PATU8988S	viability after 31 days	GCACACTCACCGAGTCCCGCTGG	RPS6KA1	ENSG00000117676	-0.942452625962287	[518]	[130,77,NaN]	-7	hSpCas9	negative selection	9863231
26546894	26546917	1	+	27869803	PATU8988S	viability after 31 days	ATCACGCACCACGTCAAGGCTGG	RPS6KA1	ENSG00000117676	-0.5877001821262987	[599]	[134,189,NaN]	-6	hSpCas9	negative selection	9863232
26551404	26551427	1	-	27869803	PATU8988S	viability after 31 days	TCTCCATCTTGGTCCGGACGCGG	RPS6KA1	ENSG00000117676	0.6333408256550509	[397]	[283,197,NaN]	7	hSpCas9	negative selection	9863233
26529946	26529969	1	-	27869803	HPAFII	viability after 35 days	CACTAGCTCCATGAGCGGCCAGG	RPS6KA1	ENSG00000117676	-0.8666297136756105	[135]	[25,50,NaN]	-5	hSpCas9	negative selection	9945677
26543207	26543230	1	-	27869803	HPAFII	viability after 35 days	CTGCTCACCTTTCTGGGACAGGG	RPS6KA1	ENSG00000117676	0.42490025946015453	[565]	[545,202,NaN]	2	hSpCas9	negative selection	9945678
26544153	26544176	1	-	27869803	HPAFII	viability after 35 days	GGGCAGATAGGTCTGACACCTGG	RPS6KA1	ENSG00000117676	1.6053526562844314	[68]	[86,127,NaN]	9	hSpCas9	negative selection	9945679
26546023	26546046	1	-	27869803	HPAFII	viability after 35 days	GCACACTCACCGAGTCCCGCTGG	RPS6KA1	ENSG00000117676	-1.6937995723192762	[202]	[35,26,NaN]	-7	hSpCas9	negative selection	9945680
26546894	26546917	1	+	27869803	HPAFII	viability after 35 days	ATCACGCACCACGTCAAGGCTGG	RPS6KA1	ENSG00000117676	-1.1330487268531466	[245]	[92,15,NaN]	-6	hSpCas9	negative selection	9945681
26551404	26551427	1	-	27869803	HPAFII	viability after 35 days	TCTCCATCTTGGTCCGGACGCGG	RPS6KA1	ENSG00000117676	1.5478377272632833	[145]	[304,115,NaN]	9	hSpCas9	negative selection	9945682
26529946	26529969	1	-	27869803	HPAFII	viability after 31 days	CACTAGCTCCATGAGCGGCCAGG	RPS6KA1	ENSG00000117676	0.13699847781967633	[135]	[59,109,NaN]	1	hSpCas9	negative selection	10028126
26543207	26543230	1	-	27869803	HPAFII	viability after 31 days	CTGCTCACCTTTCTGGGACAGGG	RPS6KA1	ENSG00000117676	0.5352779079051937	[565]	[534,378,NaN]	4	hSpCas9	negative selection	10028127
26544153	26544176	1	-	27869803	HPAFII	viability after 31 days	GGGCAGATAGGTCTGACACCTGG	RPS6KA1	ENSG00000117676	1.498033057257178	[68]	[61,160,NaN]	9	hSpCas9	negative selection	10028128
26546023	26546046	1	-	27869803	HPAFII	viability after 31 days	GCACACTCACCGAGTCCCGCTGG	RPS6KA1	ENSG00000117676	-2.0820474165074923	[202]	[35,16,NaN]	-8	hSpCas9	negative selection	10028129
26546894	26546917	1	+	27869803	HPAFII	viability after 31 days	ATCACGCACCACGTCAAGGCTGG	RPS6KA1	ENSG00000117676	0.05303219617339577	[245]	[192,88,NaN]	0	hSpCas9	negative selection	10028130
26551404	26551427	1	-	27869803	HPAFII	viability after 31 days	TCTCCATCTTGGTCCGGACGCGG	RPS6KA1	ENSG00000117676	1.1938536806775897	[145]	[308,54,NaN]	8	hSpCas9	negative selection	10028131
26557006	26557029	1	-	28162770	P31FUJ	viability	AGGGTGGCTTGATCTCACGACGG	RPS6KA1	ENSG00000117676	0.0952519932698253	[234]	[294]	1	hSpCas9	negative selection	10228071
26558823	26558846	1	-	28162770	P31FUJ	viability	GCTGATGGGCCCCAGCGCTGGGG	RPS6KA1	ENSG00000117676	-0.5817505132354501	[255]	[200]	-5	hSpCas9	negative selection	10228072
26547204	26547227	1	+	28162770	P31FUJ	viability	AAAGTCACCCGGCCTGACAGTGG	RPS6KA1	ENSG00000117676	-0.5547302993017411	[69]	[55]	-5	hSpCas9	negative selection	10228073
26553384	26553407	1	+	28162770	P31FUJ	viability	TTTGCAGGTGATGTTCACGGAGG	RPS6KA1	ENSG00000117676	0.6173023651025626	[303]	[547]	7	hSpCas9	negative selection	10228074
26557022	26557045	1	-	28162770	P31FUJ	viability	GCCACTGCTGGCTTGAAGGGTGG	RPS6KA1	ENSG00000117676	0.47847674608817803	[101]	[166]	5	hSpCas9	negative selection	10228075
26558910	26558933	1	+	28162770	P31FUJ	viability	GCAGGCACCCCTGCACTCGGTGG	RPS6KA1	ENSG00000117676	0.3308497900613655	[340]	[503]	3	hSpCas9	negative selection	10228076
26561535	26561558	1	+	28162770	P31FUJ	viability	GTGACAGAGCTGATGCGGGGTGG	RPS6KA1	ENSG00000117676	-0.10385434719699428	[245]	[268]	-1	hSpCas9	negative selection	10228077
26561585	26561608	1	+	28162770	P31FUJ	viability	GAAGTTCTTCTCAGAGCGGGAGG	RPS6KA1	ENSG00000117676	0.00709012160697213	[198]	[234]	0	hSpCas9	negative selection	10228078
26555164	26555187	1	+	28162770	P31FUJ	viability	CGGGCTCCCTGCCCTTCCAGGGG	RPS6KA1	ENSG00000117676	-0.1642708227435632	[554]	[581]	-1	hSpCas9	negative selection	10228079
26555553	26555576	1	-	28162770	P31FUJ	viability	GCTTCAGTGCTCAGAAACTGGGG	RPS6KA1	ENSG00000117676	0.5745527176432255	[107]	[188]	6	hSpCas9	negative selection	10228080
26557006	26557029	1	-	28162770	TF1	viability	AGGGTGGCTTGATCTCACGACGG	RPS6KA1	ENSG00000117676	NaN	[NaN]	[40]	1	hSpCas9	negative selection	10397437
26558823	26558846	1	-	28162770	TF1	viability	GCTGATGGGCCCCAGCGCTGGGG	RPS6KA1	ENSG00000117676	NaN	[NaN]	[127]	1	hSpCas9	negative selection	10397438
26547204	26547227	1	+	28162770	TF1	viability	AAAGTCACCCGGCCTGACAGTGG	RPS6KA1	ENSG00000117676	NaN	[NaN]	[25]	1	hSpCas9	negative selection	10397439
26553384	26553407	1	+	28162770	TF1	viability	TTTGCAGGTGATGTTCACGGAGG	RPS6KA1	ENSG00000117676	NaN	[NaN]	[132]	1	hSpCas9	negative selection	10397440
26557022	26557045	1	-	28162770	TF1	viability	GCCACTGCTGGCTTGAAGGGTGG	RPS6KA1	ENSG00000117676	NaN	[NaN]	[57]	1	hSpCas9	negative selection	10397441
26558910	26558933	1	+	28162770	TF1	viability	GCAGGCACCCCTGCACTCGGTGG	RPS6KA1	ENSG00000117676	NaN	[NaN]	[199]	1	hSpCas9	negative selection	10397442
26561535	26561558	1	+	28162770	TF1	viability	GTGACAGAGCTGATGCGGGGTGG	RPS6KA1	ENSG00000117676	NaN	[NaN]	[263]	1	hSpCas9	negative selection	10397443
26561585	26561608	1	+	28162770	TF1	viability	GAAGTTCTTCTCAGAGCGGGAGG	RPS6KA1	ENSG00000117676	NaN	[NaN]	[89]	1	hSpCas9	negative selection	10397444
26555164	26555187	1	+	28162770	TF1	viability	CGGGCTCCCTGCCCTTCCAGGGG	RPS6KA1	ENSG00000117676	NaN	[NaN]	[296]	1	hSpCas9	negative selection	10397445
26555553	26555576	1	-	28162770	TF1	viability	GCTTCAGTGCTCAGAAACTGGGG	RPS6KA1	ENSG00000117676	NaN	[NaN]	[45]	1	hSpCas9	negative selection	10397446
26557006	26557029	1	-	28162770	SKM1	viability	AGGGTGGCTTGATCTCACGACGG	RPS6KA1	ENSG00000117676	-1.1137678223991154	[70]	[57]	-7	hSpCas9	negative selection	10566803
26558823	26558846	1	-	28162770	SKM1	viability	GCTGATGGGCCCCAGCGCTGGGG	RPS6KA1	ENSG00000117676	-1.4894263589351346	[53]	[33]	-7	hSpCas9	negative selection	10566804
26547204	26547227	1	+	28162770	SKM1	viability	AAAGTCACCCGGCCTGACAGTGG	RPS6KA1	ENSG00000117676	0.0625210845580586	[12]	[23]	0	hSpCas9	negative selection	10566805
26553384	26553407	1	+	28162770	SKM1	viability	TTTGCAGGTGATGTTCACGGAGG	RPS6KA1	ENSG00000117676	0.088361089493318	[82]	[155]	0	hSpCas9	negative selection	10566806
26557022	26557045	1	-	28162770	SKM1	viability	GCCACTGCTGGCTTGAAGGGTGG	RPS6KA1	ENSG00000117676	-1.0388130870951537	[42]	[36]	-6	hSpCas9	negative selection	10566807
26558910	26558933	1	+	28162770	SKM1	viability	GCAGGCACCCCTGCACTCGGTGG	RPS6KA1	ENSG00000117676	-0.3936673761297038	[80]	[108]	-3	hSpCas9	negative selection	10566808
26561535	26561558	1	+	28162770	SKM1	viability	GTGACAGAGCTGATGCGGGGTGG	RPS6KA1	ENSG00000117676	-0.42968427524324515	[47]	[62]	-4	hSpCas9	negative selection	10566809
26561585	26561608	1	+	28162770	SKM1	viability	GAAGTTCTTCTCAGAGCGGGAGG	RPS6KA1	ENSG00000117676	-0.3118069657028216	[32]	[46]	-3	hSpCas9	negative selection	10566810
26555164	26555187	1	+	28162770	SKM1	viability	CGGGCTCCCTGCCCTTCCAGGGG	RPS6KA1	ENSG00000117676	-0.18627608361896242	[120]	[187]	-1	hSpCas9	negative selection	10566811
26555553	26555576	1	-	28162770	SKM1	viability	GCTTCAGTGCTCAGAAACTGGGG	RPS6KA1	ENSG00000117676	-0.028452575489431586	[14]	[25]	0	hSpCas9	negative selection	10566812
26557006	26557029	1	-	28162770	SKM1	viability	AGGGTGGCTTGATCTCACGACGG	RPS6KA1	ENSG00000117676	-1.1137678223991154	[70]	[57]	-7	hSpCas9	negative selection	10736169
26558823	26558846	1	-	28162770	SKM1	viability	GCTGATGGGCCCCAGCGCTGGGG	RPS6KA1	ENSG00000117676	-1.4894263589351346	[53]	[33]	-7	hSpCas9	negative selection	10736170
26547204	26547227	1	+	28162770	SKM1	viability	AAAGTCACCCGGCCTGACAGTGG	RPS6KA1	ENSG00000117676	0.0625210845580586	[12]	[23]	0	hSpCas9	negative selection	10736171
26553384	26553407	1	+	28162770	SKM1	viability	TTTGCAGGTGATGTTCACGGAGG	RPS6KA1	ENSG00000117676	0.088361089493318	[82]	[155]	0	hSpCas9	negative selection	10736172
26557022	26557045	1	-	28162770	SKM1	viability	GCCACTGCTGGCTTGAAGGGTGG	RPS6KA1	ENSG00000117676	-1.0388130870951537	[42]	[36]	-6	hSpCas9	negative selection	10736173
26558910	26558933	1	+	28162770	SKM1	viability	GCAGGCACCCCTGCACTCGGTGG	RPS6KA1	ENSG00000117676	-0.3936673761297038	[80]	[108]	-3	hSpCas9	negative selection	10736174
26561535	26561558	1	+	28162770	SKM1	viability	GTGACAGAGCTGATGCGGGGTGG	RPS6KA1	ENSG00000117676	-0.42968427524324515	[47]	[62]	-4	hSpCas9	negative selection	10736175
26561585	26561608	1	+	28162770	SKM1	viability	GAAGTTCTTCTCAGAGCGGGAGG	RPS6KA1	ENSG00000117676	-0.3118069657028216	[32]	[46]	-3	hSpCas9	negative selection	10736176
26555164	26555187	1	+	28162770	SKM1	viability	CGGGCTCCCTGCCCTTCCAGGGG	RPS6KA1	ENSG00000117676	-0.18627608361896242	[120]	[187]	-1	hSpCas9	negative selection	10736177
26555553	26555576	1	-	28162770	SKM1	viability	GCTTCAGTGCTCAGAAACTGGGG	RPS6KA1	ENSG00000117676	-0.028452575489431586	[14]	[25]	0	hSpCas9	negative selection	10736178
26557006	26557029	1	-	28162770	PL21	viability	AGGGTGGCTTGATCTCACGACGG	RPS6KA1	ENSG00000117676	-1.1894271972734054	[261]	[49]	-7	hSpCas9	negative selection	10905535
26558823	26558846	1	-	28162770	PL21	viability	GCTGATGGGCCCCAGCGCTGGGG	RPS6KA1	ENSG00000117676	-2.8873232267610196	[169]	[9]	-9	hSpCas9	negative selection	10905536
26547204	26547227	1	+	28162770	PL21	viability	AAAGTCACCCGGCCTGACAGTGG	RPS6KA1	ENSG00000117676	-0.05224754714496527	[80]	[33]	0	hSpCas9	negative selection	10905537
26553384	26553407	1	+	28162770	PL21	viability	TTTGCAGGTGATGTTCACGGAGG	RPS6KA1	ENSG00000117676	0.712741892147955	[292]	[208]	6	hSpCas9	negative selection	10905538
26557022	26557045	1	-	28162770	PL21	viability	GCCACTGCTGGCTTGAAGGGTGG	RPS6KA1	ENSG00000117676	-0.18233002233309314	[145]	[55]	-1	hSpCas9	negative selection	10905539
26558910	26558933	1	+	28162770	PL21	viability	GCAGGCACCCCTGCACTCGGTGG	RPS6KA1	ENSG00000117676	-0.5626841475979119	[318]	[93]	-4	hSpCas9	negative selection	10905540
26561535	26561558	1	+	28162770	PL21	viability	GTGACAGAGCTGATGCGGGGTGG	RPS6KA1	ENSG00000117676	0.33560303178443884	[192]	[105]	3	hSpCas9	negative selection	10905541
26561585	26561608	1	+	28162770	PL21	viability	GAAGTTCTTCTCAGAGCGGGAGG	RPS6KA1	ENSG00000117676	-0.18591881781775776	[114]	[43]	-1	hSpCas9	negative selection	10905542
26555164	26555187	1	+	28162770	PL21	viability	CGGGCTCCCTGCCCTTCCAGGGG	RPS6KA1	ENSG00000117676	-0.2958178801730912	[439]	[155]	-2	hSpCas9	negative selection	10905543
26555553	26555576	1	-	28162770	PL21	viability	GCTTCAGTGCTCAGAAACTGGGG	RPS6KA1	ENSG00000117676	-0.13170394926312512	[72]	[28]	-1	hSpCas9	negative selection	10905544
26557006	26557029	1	-	28162770	P31FUJ	viability	AGGGTGGCTTGATCTCACGACGG	RPS6KA1	ENSG00000117676	0.0952519932698253	[234]	[294]	1	hSpCas9	negative selection	11074901
26558823	26558846	1	-	28162770	P31FUJ	viability	GCTGATGGGCCCCAGCGCTGGGG	RPS6KA1	ENSG00000117676	-0.5817505132354501	[255]	[200]	-5	hSpCas9	negative selection	11074902
26547204	26547227	1	+	28162770	P31FUJ	viability	AAAGTCACCCGGCCTGACAGTGG	RPS6KA1	ENSG00000117676	-0.5547302993017411	[69]	[55]	-5	hSpCas9	negative selection	11074903
26553384	26553407	1	+	28162770	P31FUJ	viability	TTTGCAGGTGATGTTCACGGAGG	RPS6KA1	ENSG00000117676	0.6173023651025626	[303]	[547]	7	hSpCas9	negative selection	11074904
26557022	26557045	1	-	28162770	P31FUJ	viability	GCCACTGCTGGCTTGAAGGGTGG	RPS6KA1	ENSG00000117676	0.47847674608817803	[101]	[166]	5	hSpCas9	negative selection	11074905
26558910	26558933	1	+	28162770	P31FUJ	viability	GCAGGCACCCCTGCACTCGGTGG	RPS6KA1	ENSG00000117676	0.3308497900613655	[340]	[503]	3	hSpCas9	negative selection	11074906
26561535	26561558	1	+	28162770	P31FUJ	viability	GTGACAGAGCTGATGCGGGGTGG	RPS6KA1	ENSG00000117676	-0.10385434719699428	[245]	[268]	-1	hSpCas9	negative selection	11074907
26561585	26561608	1	+	28162770	P31FUJ	viability	GAAGTTCTTCTCAGAGCGGGAGG	RPS6KA1	ENSG00000117676	0.00709012160697213	[198]	[234]	0	hSpCas9	negative selection	11074908
26555164	26555187	1	+	28162770	P31FUJ	viability	CGGGCTCCCTGCCCTTCCAGGGG	RPS6KA1	ENSG00000117676	-0.1642708227435632	[554]	[581]	-1	hSpCas9	negative selection	11074909
26555553	26555576	1	-	28162770	P31FUJ	viability	GCTTCAGTGCTCAGAAACTGGGG	RPS6KA1	ENSG00000117676	0.5745527176432255	[107]	[188]	6	hSpCas9	negative selection	11074910
26557006	26557029	1	-	28162770	OCIAML5	viability	AGGGTGGCTTGATCTCACGACGG	RPS6KA1	ENSG00000117676	0.7364018733586947	[136]	[411]	6	hSpCas9	negative selection	11244267
26558823	26558846	1	-	28162770	OCIAML5	viability	GCTGATGGGCCCCAGCGCTGGGG	RPS6KA1	ENSG00000117676	-1.093884490788095	[161]	[136]	-6	hSpCas9	negative selection	11244268
26547204	26547227	1	+	28162770	OCIAML5	viability	AAAGTCACCCGGCCTGACAGTGG	RPS6KA1	ENSG00000117676	-1.1891015581415676	[47]	[37]	-6	hSpCas9	negative selection	11244269
26553384	26553407	1	+	28162770	OCIAML5	viability	TTTGCAGGTGATGTTCACGGAGG	RPS6KA1	ENSG00000117676	0.987317205386245	[139]	[500]	8	hSpCas9	negative selection	11244270
26557022	26557045	1	-	28162770	OCIAML5	viability	GCCACTGCTGGCTTGAAGGGTGG	RPS6KA1	ENSG00000117676	0.5002351730668843	[93]	[239]	4	hSpCas9	negative selection	11244271
26558910	26558933	1	+	28162770	OCIAML5	viability	GCAGGCACCCCTGCACTCGGTGG	RPS6KA1	ENSG00000117676	0.061633582741782655	[154]	[291]	0	hSpCas9	negative selection	11244272
26561535	26561558	1	+	28162770	OCIAML5	viability	GTGACAGAGCTGATGCGGGGTGG	RPS6KA1	ENSG00000117676	0.5568964140051625	[118]	[315]	5	hSpCas9	negative selection	11244273
26561585	26561608	1	+	28162770	OCIAML5	viability	GAAGTTCTTCTCAGAGCGGGAGG	RPS6KA1	ENSG00000117676	1.1827634132991018	[132]	[544]	8	hSpCas9	negative selection	11244274
26555164	26555187	1	+	28162770	OCIAML5	viability	CGGGCTCCCTGCCCTTCCAGGGG	RPS6KA1	ENSG00000117676	0.47993078193463257	[256]	[646]	4	hSpCas9	negative selection	11244275
26555553	26555576	1	-	28162770	OCIAML5	viability	GCTTCAGTGCTCAGAAACTGGGG	RPS6KA1	ENSG00000117676	0.9180073351141476	[55]	[190]	7	hSpCas9	negative selection	11244276
26557006	26557029	1	-	28162770	EOL1	viability	AGGGTGGCTTGATCTCACGACGG	RPS6KA1	ENSG00000117676	-0.09611169899555855	[421]	[207]	0	hSpCas9	negative selection	11413633
26558823	26558846	1	-	28162770	EOL1	viability	GCTGATGGGCCCCAGCGCTGGGG	RPS6KA1	ENSG00000117676	-1.8956311908446533	[225]	[31]	-8	hSpCas9	negative selection	11413634
26547204	26547227	1	+	28162770	EOL1	viability	AAAGTCACCCGGCCTGACAGTGG	RPS6KA1	ENSG00000117676	-0.1706094614698055	[93]	[43]	-1	hSpCas9	negative selection	11413635
26553384	26553407	1	+	28162770	EOL1	viability	TTTGCAGGTGATGTTCACGGAGG	RPS6KA1	ENSG00000117676	0.5164131325463787	[555]	[418]	5	hSpCas9	negative selection	11413636
26557022	26557045	1	-	28162770	EOL1	viability	GCCACTGCTGGCTTGAAGGGTGG	RPS6KA1	ENSG00000117676	0.12484642205636577	[281]	[161]	1	hSpCas9	negative selection	11413637
26558910	26558933	1	+	28162770	EOL1	viability	GCAGGCACCCCTGCACTCGGTGG	RPS6KA1	ENSG00000117676	-0.3227622819702428	[583]	[245]	-2	hSpCas9	negative selection	11413638
26561535	26561558	1	+	28162770	EOL1	viability	GTGACAGAGCTGATGCGGGGTGG	RPS6KA1	ENSG00000117676	-0.699484293829214	[261]	[84]	-5	hSpCas9	negative selection	11413639
26561585	26561608	1	+	28162770	EOL1	viability	GAAGTTCTTCTCAGAGCGGGAGG	RPS6KA1	ENSG00000117676	0.21480364613935277	[174]	[106]	2	hSpCas9	negative selection	11413640
26555164	26555187	1	+	28162770	EOL1	viability	CGGGCTCCCTGCCCTTCCAGGGG	RPS6KA1	ENSG00000117676	-0.6778418009088059	[582]	[191]	-5	hSpCas9	negative selection	11413641
26555553	26555576	1	-	28162770	EOL1	viability	GCTTCAGTGCTCAGAAACTGGGG	RPS6KA1	ENSG00000117676	0.7980153656416031	[130]	[119]	7	hSpCas9	negative selection	11413642
26557006	26557029	1	-	28162770	MOLM13	viability	AGGGTGGCTTGATCTCACGACGG	RPS6KA1	ENSG00000117676	-1.3680346927097964	[356]	[99]	-6	hSpCas9	negative selection	11582999
26558823	26558846	1	-	28162770	MOLM13	viability	GCTGATGGGCCCCAGCGCTGGGG	RPS6KA1	ENSG00000117676	-3.760929308951302	[224]	[11]	-9	hSpCas9	negative selection	11583000
26547204	26547227	1	+	28162770	MOLM13	viability	AAAGTCACCCGGCCTGACAGTGG	RPS6KA1	ENSG00000117676	-1.4174680525142986	[132]	[35]	-6	hSpCas9	negative selection	11583001
26553384	26553407	1	+	28162770	MOLM13	viability	TTTGCAGGTGATGTTCACGGAGG	RPS6KA1	ENSG00000117676	-0.9202724117428703	[389]	[148]	-5	hSpCas9	negative selection	11583002
26557022	26557045	1	-	28162770	MOLM13	viability	GCCACTGCTGGCTTGAAGGGTGG	RPS6KA1	ENSG00000117676	-2.2246015834810224	[180]	[27]	-7	hSpCas9	negative selection	11583003
26558910	26558933	1	+	28162770	MOLM13	viability	GCAGGCACCCCTGCACTCGGTGG	RPS6KA1	ENSG00000117676	-0.24073158692766555	[419]	[256]	-1	hSpCas9	negative selection	11583004
26561535	26561558	1	+	28162770	MOLM13	viability	GTGACAGAGCTGATGCGGGGTGG	RPS6KA1	ENSG00000117676	-1.9173036068008	[302]	[57]	-7	hSpCas9	negative selection	11583005
26561585	26561608	1	+	28162770	MOLM13	viability	GAAGTTCTTCTCAGAGCGGGAGG	RPS6KA1	ENSG00000117676	-2.109035800111159	[178]	[29]	-7	hSpCas9	negative selection	11583006
26555164	26555187	1	+	28162770	MOLM13	viability	CGGGCTCCCTGCCCTTCCAGGGG	RPS6KA1	ENSG00000117676	-1.676642462469336	[534]	[120]	-7	hSpCas9	negative selection	11583007
26555553	26555576	1	-	28162770	MOLM13	viability	GCTTCAGTGCTCAGAAACTGGGG	RPS6KA1	ENSG00000117676	-1.9269702357966345	[141]	[26]	-7	hSpCas9	negative selection	11583008
26557006	26557029	1	-	28162770	HEL	viability	AGGGTGGCTTGATCTCACGACGG	RPS6KA1	ENSG00000117676	-0.12923321199376234	[291]	[170]	-1	hSpCas9	negative selection	11752365
26558823	26558846	1	-	28162770	HEL	viability	GCTGATGGGCCCCAGCGCTGGGG	RPS6KA1	ENSG00000117676	-1.6244833707968704	[206]	[42]	-7	hSpCas9	negative selection	11752366
26547204	26547227	1	+	28162770	HEL	viability	AAAGTCACCCGGCCTGACAGTGG	RPS6KA1	ENSG00000117676	-0.7606168622308513	[81]	[30]	-5	hSpCas9	negative selection	11752367
26553384	26553407	1	+	28162770	HEL	viability	TTTGCAGGTGATGTTCACGGAGG	RPS6KA1	ENSG00000117676	0.31523689228840246	[388]	[309]	2	hSpCas9	negative selection	11752368
26557022	26557045	1	-	28162770	HEL	viability	GCCACTGCTGGCTTGAAGGGTGG	RPS6KA1	ENSG00000117676	0.2782502748849488	[214]	[166]	2	hSpCas9	negative selection	11752369
26558910	26558933	1	+	28162770	HEL	viability	GCAGGCACCCCTGCACTCGGTGG	RPS6KA1	ENSG00000117676	0.6074057588880762	[371]	[362]	5	hSpCas9	negative selection	11752370
26561535	26561558	1	+	28162770	HEL	viability	GTGACAGAGCTGATGCGGGGTGG	RPS6KA1	ENSG00000117676	-0.7598077230952901	[229]	[86]	-5	hSpCas9	negative selection	11752371
26561585	26561608	1	+	28162770	HEL	viability	GAAGTTCTTCTCAGAGCGGGAGG	RPS6KA1	ENSG00000117676	0.6145419401697049	[154]	[151]	5	hSpCas9	negative selection	11752372
26555164	26555187	1	+	28162770	HEL	viability	CGGGCTCCCTGCCCTTCCAGGGG	RPS6KA1	ENSG00000117676	-0.4755811351884045	[507]	[233]	-3	hSpCas9	negative selection	11752373
26555553	26555576	1	-	28162770	HEL	viability	GCTTCAGTGCTCAGAAACTGGGG	RPS6KA1	ENSG00000117676	-0.3732027118686647	[90]	[44]	-3	hSpCas9	negative selection	11752374
26557006	26557029	1	-	28162770	MV411	viability	AGGGTGGCTTGATCTCACGACGG	RPS6KA1	ENSG00000117676	-0.7040639315260349	[233]	[120]	-5	hSpCas9	negative selection	11921731
26558823	26558846	1	-	28162770	MV411	viability	GCTGATGGGCCCCAGCGCTGGGG	RPS6KA1	ENSG00000117676	-1.8918372378193526	[162]	[36]	-8	hSpCas9	negative selection	11921732
26547204	26547227	1	+	28162770	MV411	viability	AAAGTCACCCGGCCTGACAGTGG	RPS6KA1	ENSG00000117676	-0.5540167698351444	[60]	[34]	-4	hSpCas9	negative selection	11921733
26553384	26553407	1	+	28162770	MV411	viability	TTTGCAGGTGATGTTCACGGAGG	RPS6KA1	ENSG00000117676	0.21680593212911198	[237]	[232]	1	hSpCas9	negative selection	11921734
26557022	26557045	1	-	28162770	MV411	viability	GCCACTGCTGGCTTGAAGGGTGG	RPS6KA1	ENSG00000117676	-0.07238288114259579	[170]	[136]	0	hSpCas9	negative selection	11921735
26558910	26558933	1	+	28162770	MV411	viability	GCAGGCACCCCTGCACTCGGTGG	RPS6KA1	ENSG00000117676	0.019168563109658088	[245]	[209]	0	hSpCas9	negative selection	11921736
26561535	26561558	1	+	28162770	MV411	viability	GTGACAGAGCTGATGCGGGGTGG	RPS6KA1	ENSG00000117676	0.07516860887216387	[230]	[204]	0	hSpCas9	negative selection	11921737
26561585	26561608	1	+	28162770	MV411	viability	GAAGTTCTTCTCAGAGCGGGAGG	RPS6KA1	ENSG00000117676	0.33341077389262813	[113]	[120]	3	hSpCas9	negative selection	11921738
26555164	26555187	1	+	28162770	MV411	viability	CGGGCTCCCTGCCCTTCCAGGGG	RPS6KA1	ENSG00000117676	-0.8477196822575648	[281]	[131]	-5	hSpCas9	negative selection	11921739
26555553	26555576	1	-	28162770	MV411	viability	GCTTCAGTGCTCAGAAACTGGGG	RPS6KA1	ENSG00000117676	-0.27193660831080413	[85]	[59]	-2	hSpCas9	negative selection	11921740
26557006	26557029	1	-	28162770	MONOMAC1	viability	AGGGTGGCTTGATCTCACGACGG	RPS6KA1	ENSG00000117676	0.6766174190750331	[160]	[294]	6	hSpCas9	negative selection	12091097
26558823	26558846	1	-	28162770	MONOMAC1	viability	GCTGATGGGCCCCAGCGCTGGGG	RPS6KA1	ENSG00000117676	0.5596920019280824	[115]	[195]	5	hSpCas9	negative selection	12091098
26547204	26547227	1	+	28162770	MONOMAC1	viability	AAAGTCACCCGGCCTGACAGTGG	RPS6KA1	ENSG00000117676	1.060760910408093	[45]	[109]	8	hSpCas9	negative selection	12091099
26553384	26553407	1	+	28162770	MONOMAC1	viability	TTTGCAGGTGATGTTCACGGAGG	RPS6KA1	ENSG00000117676	0.9870670895525205	[179]	[408]	8	hSpCas9	negative selection	12091100
26557022	26557045	1	-	28162770	MONOMAC1	viability	GCCACTGCTGGCTTGAAGGGTGG	RPS6KA1	ENSG00000117676	0.31880129300678217	[113]	[162]	3	hSpCas9	negative selection	12091101
26558910	26558933	1	+	28162770	MONOMAC1	viability	GCAGGCACCCCTGCACTCGGTGG	RPS6KA1	ENSG00000117676	-0.19024768139691461	[211]	[212]	-2	hSpCas9	negative selection	12091102
26561535	26561558	1	+	28162770	MONOMAC1	viability	GTGACAGAGCTGATGCGGGGTGG	RPS6KA1	ENSG00000117676	0.09341301635464055	[138]	[169]	0	hSpCas9	negative selection	12091103
26561585	26561608	1	+	28162770	MONOMAC1	viability	GAAGTTCTTCTCAGAGCGGGAGG	RPS6KA1	ENSG00000117676	-0.8510409922103611	[106]	[67]	-6	hSpCas9	negative selection	12091104
26555164	26555187	1	+	28162770	MONOMAC1	viability	CGGGCTCCCTGCCCTTCCAGGGG	RPS6KA1	ENSG00000117676	0.2774491173000331	[207]	[288]	3	hSpCas9	negative selection	12091105
26555553	26555576	1	-	28162770	MONOMAC1	viability	GCTTCAGTGCTCAGAAACTGGGG	RPS6KA1	ENSG00000117676	-0.4085409522532656	[65]	[56]	-4	hSpCas9	negative selection	12091106
26557006	26557029	1	-	28162770	OCIAML2	viability	AGGGTGGCTTGATCTCACGACGG	RPS6KA1	ENSG00000117676	-2.040945549998916	[48]	[65]	-8	hSpCas9	negative selection	12260463
26558823	26558846	1	-	28162770	OCIAML2	viability	GCTGATGGGCCCCAGCGCTGGGG	RPS6KA1	ENSG00000117676	-2.6475075873262406	[25]	[22]	-9	hSpCas9	negative selection	12260464
26547204	26547227	1	+	28162770	OCIAML2	viability	AAAGTCACCCGGCCTGACAGTGG	RPS6KA1	ENSG00000117676	-2.3331263014922263	[19]	[21]	-8	hSpCas9	negative selection	12260465
26553384	26553407	1	+	28162770	OCIAML2	viability	TTTGCAGGTGATGTTCACGGAGG	RPS6KA1	ENSG00000117676	-0.6595325014987403	[54]	[192]	-5	hSpCas9	negative selection	12260466
26557022	26557045	1	-	28162770	OCIAML2	viability	GCCACTGCTGGCTTGAAGGGTGG	RPS6KA1	ENSG00000117676	-1.615019734577336	[20]	[37]	-7	hSpCas9	negative selection	12260467
26558910	26558933	1	+	28162770	OCIAML2	viability	GCAGGCACCCCTGCACTCGGTGG	RPS6KA1	ENSG00000117676	-1.5071557012672754	[59]	[116]	-7	hSpCas9	negative selection	12260468
26561535	26561558	1	+	28162770	OCIAML2	viability	GTGACAGAGCTGATGCGGGGTGG	RPS6KA1	ENSG00000117676	-2.237969068451886	[39]	[46]	-8	hSpCas9	negative selection	12260469
26561585	26561608	1	+	28162770	OCIAML2	viability	GAAGTTCTTCTCAGAGCGGGAGG	RPS6KA1	ENSG00000117676	-1.0921182019884315	[19]	[51]	-6	hSpCas9	negative selection	12260470
26555164	26555187	1	+	28162770	OCIAML2	viability	CGGGCTCCCTGCCCTTCCAGGGG	RPS6KA1	ENSG00000117676	-2.2115426039250305	[60]	[72]	-8	hSpCas9	negative selection	12260471
26555553	26555576	1	-	28162770	OCIAML2	viability	GCTTCAGTGCTCAGAAACTGGGG	RPS6KA1	ENSG00000117676	-4.345098943158303	[10]	[2]	-9	hSpCas9	negative selection	12260472
26557006	26557029	1	-	28162770	OCIAML3	viability	AGGGTGGCTTGATCTCACGACGG	RPS6KA1	ENSG00000117676	-3.354819976444737	[60]	[17]	-9	hSpCas9	negative selection	12429829
26558823	26558846	1	-	28162770	OCIAML3	viability	GCTGATGGGCCCCAGCGCTGGGG	RPS6KA1	ENSG00000117676	-2.7562790692230403	[46]	[20]	-9	hSpCas9	negative selection	12429830
26547204	26547227	1	+	28162770	OCIAML3	viability	AAAGTCACCCGGCCTGACAGTGG	RPS6KA1	ENSG00000117676	-2.487092436407651	[12]	[6]	-9	hSpCas9	negative selection	12429831
26553384	26553407	1	+	28162770	OCIAML3	viability	TTTGCAGGTGATGTTCACGGAGG	RPS6KA1	ENSG00000117676	-0.6709696221390472	[76]	[145]	-5	hSpCas9	negative selection	12429832
26557022	26557045	1	-	28162770	OCIAML3	viability	GCCACTGCTGGCTTGAAGGGTGG	RPS6KA1	ENSG00000117676	-1.4829763279354191	[24]	[26]	-7	hSpCas9	negative selection	12429833
26558910	26558933	1	+	28162770	OCIAML3	viability	GCAGGCACCCCTGCACTCGGTGG	RPS6KA1	ENSG00000117676	-0.5501533507347358	[80]	[166]	-4	hSpCas9	negative selection	12429834
26561535	26561558	1	+	28162770	OCIAML3	viability	GTGACAGAGCTGATGCGGGGTGG	RPS6KA1	ENSG00000117676	-0.08250730154402813	[46]	[133]	0	hSpCas9	negative selection	12429835
26561585	26561608	1	+	28162770	OCIAML3	viability	GAAGTTCTTCTCAGAGCGGGAGG	RPS6KA1	ENSG00000117676	-1.0221012924284532	[36]	[54]	-6	hSpCas9	negative selection	12429836
26555164	26555187	1	+	28162770	OCIAML3	viability	CGGGCTCCCTGCCCTTCCAGGGG	RPS6KA1	ENSG00000117676	-0.8291630135825205	[122]	[208]	-6	hSpCas9	negative selection	12429837
26555553	26555576	1	-	28162770	OCIAML3	viability	GCTTCAGTGCTCAGAAACTGGGG	RPS6KA1	ENSG00000117676	-3.8164000616606115	[27]	[5]	-9	hSpCas9	negative selection	12429838