Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:9252
• Symbol:RPS6KA5
• Description:ribosomal protein S6 kinase A5

DataSource: http://genomecrispr.dkfz.de/#!/results/RPS6KA5

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
90923112	90923135	14	-	26472758	Jiyoye	viability	GGGAGATTCAGGACATGACAAGG	RPS6KA5	ENSG00000100784	-0.6638440818141442	[228]	[108]	-5	hSpCas9	negative selection	140263
90900190	90900213	14	-	26472758	Jiyoye	viability	AGATTTGAAGGACAAACCCCTGG	RPS6KA5	ENSG00000100784	0.26857014327636664	[130]	[118]	2	hSpCas9	negative selection	140264
90899372	90899395	14	-	26472758	Jiyoye	viability	ACAGCTCTGAAACTCTGTGAAGG	RPS6KA5	ENSG00000100784	-0.2863976171469521	[130]	[80]	-2	hSpCas9	negative selection	140265
91001130	91001153	14	-	26472758	Jiyoye	viability	GACAGGACATGCTGAGAAGGTGG	RPS6KA5	ENSG00000100784	0.3315111115738012	[273]	[259]	2	hSpCas9	negative selection	140267
91001087	91001110	14	-	26472758	Jiyoye	viability	CTGAAGGTCCTAGGAACTGGAGG	RPS6KA5	ENSG00000100784	-0.5097688787665681	[269]	[142]	-4	hSpCas9	negative selection	140268
90894546	90894569	14	-	26472758	Jiyoye	viability	GTGATGGAACTTCTGAATGGAGG	RPS6KA5	ENSG00000100784	-0.23437064758165027	[272]	[174]	-2	hSpCas9	negative selection	140269
90894412	90894435	14	-	26472758	Jiyoye	viability	GCACAGGGATCTGAAACCTGAGG	RPS6KA5	ENSG00000100784	-2.8558590243279203	[47]	[4]	-9	hSpCas9	negative selection	140270
90943107	90943130	14	+	26472758	Jiyoye	viability	CAAAATCTGTCAGCACCACATGG	RPS6KA5	ENSG00000100784	0.022511531270548613	[46]	[35]	0	hSpCas9	negative selection	140271
90923112	90923135	14	-	26472758	KBM7	viability	GGGAGATTCAGGACATGACAAGG	RPS6KA5	ENSG00000100784	0.04302505193621582	[458,550]	[198,291]	0	hSpCas9	negative selection	331381
90900190	90900213	14	-	26472758	KBM7	viability	AGATTTGAAGGACAAACCCCTGG	RPS6KA5	ENSG00000100784	0.4120536021976651	[355,320]	[245,180]	4	hSpCas9	negative selection	331382
90899372	90899395	14	-	26472758	KBM7	viability	ACAGCTCTGAAACTCTGTGAAGG	RPS6KA5	ENSG00000100784	-0.032260743243429535	[346,250]	[137,133]	0	hSpCas9	negative selection	331383
91001130	91001153	14	-	26472758	KBM7	viability	GACAGGACATGCTGAGAAGGTGG	RPS6KA5	ENSG00000100784	0.3326329571136828	[1201,989]	[660,631]	3	hSpCas9	negative selection	331385
91001087	91001110	14	-	26472758	KBM7	viability	CTGAAGGTCCTAGGAACTGGAGG	RPS6KA5	ENSG00000100784	0.6955307812223707	[869,678]	[628,545]	7	hSpCas9	negative selection	331386
90894546	90894569	14	-	26472758	KBM7	viability	GTGATGGAACTTCTGAATGGAGG	RPS6KA5	ENSG00000100784	-0.000734261453427365	[1130,1038]	[525,495]	0	hSpCas9	negative selection	331387
90894412	90894435	14	-	26472758	KBM7	viability	GCACAGGGATCTGAAACCTGAGG	RPS6KA5	ENSG00000100784	0.7131040023399471	[97,80]	[112,28]	7	hSpCas9	negative selection	331388
90943107	90943130	14	+	26472758	KBM7	viability	CAAAATCTGTCAGCACCACATGG	RPS6KA5	ENSG00000100784	0.36066743284057023	[397,235]	[171,200]	4	hSpCas9	negative selection	331389
90923112	90923135	14	-	26472758	Raji	viability	GGGAGATTCAGGACATGACAAGG	RPS6KA5	ENSG00000100784	0.31992817075370056	[251]	[72]	3	hSpCas9	negative selection	522499
90900190	90900213	14	-	26472758	Raji	viability	AGATTTGAAGGACAAACCCCTGG	RPS6KA5	ENSG00000100784	1.2266824637459437	[115]	[62]	9	hSpCas9	negative selection	522500
90899372	90899395	14	-	26472758	Raji	viability	ACAGCTCTGAAACTCTGTGAAGG	RPS6KA5	ENSG00000100784	0.05111531572685435	[182]	[43]	0	hSpCas9	negative selection	522501
91001130	91001153	14	-	26472758	Raji	viability	GACAGGACATGCTGAGAAGGTGG	RPS6KA5	ENSG00000100784	0.6348957639108559	[443]	[159]	6	hSpCas9	negative selection	522503
91001087	91001110	14	-	26472758	Raji	viability	CTGAAGGTCCTAGGAACTGGAGG	RPS6KA5	ENSG00000100784	0.18279093803162205	[409]	[107]	1	hSpCas9	negative selection	522504
90894546	90894569	14	-	26472758	Raji	viability	GTGATGGAACTTCTGAATGGAGG	RPS6KA5	ENSG00000100784	-0.44668495740177305	[692]	[117]	-4	hSpCas9	negative selection	522505
90894412	90894435	14	-	26472758	Raji	viability	GCACAGGGATCTGAAACCTGAGG	RPS6KA5	ENSG00000100784	0.3995642868669096	[48]	[14]	4	hSpCas9	negative selection	522506
90943107	90943130	14	+	26472758	Raji	viability	CAAAATCTGTCAGCACCACATGG	RPS6KA5	ENSG00000100784	0.12599921354094668	[153]	[38]	1	hSpCas9	negative selection	522507
90923112	90923135	14	-	26472758	K562	viability	GGGAGATTCAGGACATGACAAGG	RPS6KA5	ENSG00000100784	0.9483440600686454	[317]	[517]	7	hSpCas9	negative selection	713617
90900190	90900213	14	-	26472758	K562	viability	AGATTTGAAGGACAAACCCCTGG	RPS6KA5	ENSG00000100784	0.6705539358286212	[258]	[347]	5	hSpCas9	negative selection	713618
90899372	90899395	14	-	26472758	K562	viability	ACAGCTCTGAAACTCTGTGAAGG	RPS6KA5	ENSG00000100784	1.0468581593099344	[167]	[292]	8	hSpCas9	negative selection	713619
91001130	91001153	14	-	26472758	K562	viability	GACAGGACATGCTGAGAAGGTGG	RPS6KA5	ENSG00000100784	0.4023824320158418	[941]	[1050]	3	hSpCas9	negative selection	713621
91001087	91001110	14	-	26472758	K562	viability	CTGAAGGTCCTAGGAACTGGAGG	RPS6KA5	ENSG00000100784	0.9809362103083518	[643]	[1072]	8	hSpCas9	negative selection	713622
90894546	90894569	14	-	26472758	K562	viability	GTGATGGAACTTCTGAATGGAGG	RPS6KA5	ENSG00000100784	0.4621547865716731	[797]	[927]	3	hSpCas9	negative selection	713623
90894412	90894435	14	-	26472758	K562	viability	GCACAGGGATCTGAAACCTGAGG	RPS6KA5	ENSG00000100784	1.2612925462308433	[84]	[171]	9	hSpCas9	negative selection	713624
90943107	90943130	14	+	26472758	K562	viability	CAAAATCTGTCAGCACCACATGG	RPS6KA5	ENSG00000100784	1.8423902889494657	[183]	[556]	9	hSpCas9	negative selection	713625
90872076	90872099	14	+	26627737	DLD1	viability	AAGCTACTGAGTCCGAGAACTGG	RPS6KA5	ENSG00000100784	0.2038737932265412	[816]	[449,286,164]	2	hSpCas9	negative selection	789701
90875294	90875317	14	-	26627737	DLD1	viability	AAGTTTGACGTGTACCAGCGCGG	RPS6KA5	ENSG00000100784	0.0336595520493943	[735]	[251,277,185]	0	hSpCas9	negative selection	789702
90890600	90890623	14	-	26627737	DLD1	viability	ATTTGCACGGCTAAAGCCACCGG	RPS6KA5	ENSG00000100784	1.5174568039370604	[142]	[46,167,164]	9	hSpCas9	negative selection	789703
90894427	90894450	14	-	26627737	DLD1	viability	TGATGTTGGAGTGGTGCACAGGG	RPS6KA5	ENSG00000100784	0.022308463393381994	[851]	[203,429,195]	0	hSpCas9	negative selection	789704
90900707	90900730	14	+	26627737	DLD1	viability	TAGGATGGAAGGAGCAACAAAGG	RPS6KA5	ENSG00000100784	0.27462164683926904	[359]	[135,133,137]	3	hSpCas9	negative selection	789705
90923112	90923135	14	-	26627737	DLD1	viability	GGGAGATTCAGGACATGACAAGG	RPS6KA5	ENSG00000100784	1.9910003930053357	[120]	[91,171,182]	9	hSpCas9	negative selection	789706
90872076	90872099	14	+	26627737	GBM cells	viability after 5 days	AAGCTACTGAGTCCGAGAACTGG	RPS6KA5	ENSG00000100784	-0.1291997613232283	[569]	[269,288]	-2	hSpCas9	negative selection	872016
90875294	90875317	14	-	26627737	GBM cells	viability after 5 days	AAGTTTGACGTGTACCAGCGCGG	RPS6KA5	ENSG00000100784	-0.5207550731248041	[415]	[153,156]	-7	hSpCas9	negative selection	872017
90890600	90890623	14	-	26627737	GBM cells	viability after 5 days	ATTTGCACGGCTAAAGCCACCGG	RPS6KA5	ENSG00000100784	-0.16521646253403	[114]	[57,51]	-3	hSpCas9	negative selection	872018
90894427	90894450	14	-	26627737	GBM cells	viability after 5 days	TGATGTTGGAGTGGTGCACAGGG	RPS6KA5	ENSG00000100784	0.15267046713146853	[285]	[198,141]	2	hSpCas9	negative selection	872019
90900707	90900730	14	+	26627737	GBM cells	viability after 5 days	TAGGATGGAAGGAGCAACAAAGG	RPS6KA5	ENSG00000100784	-0.22832131341042222	[307]	[117,163]	-4	hSpCas9	negative selection	872020
90923112	90923135	14	-	26627737	GBM cells	viability after 5 days	GGGAGATTCAGGACATGACAAGG	RPS6KA5	ENSG00000100784	0.5316089863909437	[108]	[72,95]	7	hSpCas9	negative selection	872021
90872076	90872099	14	+	26627737	GBM cells	viability after 13 days	AAGCTACTGAGTCCGAGAACTGG	RPS6KA5	ENSG00000100784	0.008908270022101039	[569]	[335,290]	0	hSpCas9	negative selection	954331
90875294	90875317	14	-	26627737	GBM cells	viability after 13 days	AAGTTTGACGTGTACCAGCGCGG	RPS6KA5	ENSG00000100784	-0.3808292853631629	[415]	[174,171]	-4	hSpCas9	negative selection	954332
90890600	90890623	14	-	26627737	GBM cells	viability after 13 days	ATTTGCACGGCTAAAGCCACCGG	RPS6KA5	ENSG00000100784	0.12251506223276987	[114]	[57,75]	1	hSpCas9	negative selection	954333
90894427	90894450	14	-	26627737	GBM cells	viability after 13 days	TGATGTTGGAGTGGTGCACAGGG	RPS6KA5	ENSG00000100784	0.19629556968620443	[285]	[254,114]	2	hSpCas9	negative selection	954334
90900707	90900730	14	+	26627737	GBM cells	viability after 13 days	TAGGATGGAAGGAGCAACAAAGG	RPS6KA5	ENSG00000100784	-0.13438499921012156	[307]	[170,136]	-2	hSpCas9	negative selection	954335
90923112	90923135	14	-	26627737	GBM cells	viability after 13 days	GGGAGATTCAGGACATGACAAGG	RPS6KA5	ENSG00000100784	0.5416629879599323	[108]	[127,51]	6	hSpCas9	negative selection	954336
90872076	90872099	14	+	26627737	GBM cells	viability after 21 days	AAGCTACTGAGTCCGAGAACTGG	RPS6KA5	ENSG00000100784	-0.17702082999751068	[569]	[275,271]	-2	hSpCas9	negative selection	1036646
90875294	90875317	14	-	26627737	GBM cells	viability after 21 days	AAGTTTGACGTGTACCAGCGCGG	RPS6KA5	ENSG00000100784	0.4540034654946896	[415]	[330,289]	4	hSpCas9	negative selection	1036647
90890600	90890623	14	-	26627737	GBM cells	viability after 21 days	ATTTGCACGGCTAAAGCCACCGG	RPS6KA5	ENSG00000100784	-0.15019373413584947	[114]	[60,51]	-1	hSpCas9	negative selection	1036648
90894427	90894450	14	-	26627737	GBM cells	viability after 21 days	TGATGTTGGAGTGGTGCACAGGG	RPS6KA5	ENSG00000100784	-0.11842215691247648	[285]	[139,145]	-1	hSpCas9	negative selection	1036649
90900707	90900730	14	+	26627737	GBM cells	viability after 21 days	TAGGATGGAAGGAGCAACAAAGG	RPS6KA5	ENSG00000100784	0.2128637444125448	[307]	[218,170]	2	hSpCas9	negative selection	1036650
90923112	90923135	14	-	26627737	GBM cells	viability after 21 days	GGGAGATTCAGGACATGACAAGG	RPS6KA5	ENSG00000100784	-1.1330635229977992	[108]	[26,26]	-7	hSpCas9	negative selection	1036651
90872076	90872099	14	+	26627737	RPE1	viability after 9 days	AAGCTACTGAGTCCGAGAACTGG	RPS6KA5	ENSG00000100784	0.47489455524078117	[1332]	[517,659]	3	hSpCas9	negative selection	1118961
90875294	90875317	14	-	26627737	RPE1	viability after 9 days	AAGTTTGACGTGTACCAGCGCGG	RPS6KA5	ENSG00000100784	0.5882969037288366	[1345]	[440,881]	4	hSpCas9	negative selection	1118962
90890600	90890623	14	-	26627737	RPE1	viability after 9 days	ATTTGCACGGCTAAAGCCACCGG	RPS6KA5	ENSG00000100784	0.050601041065828856	[233]	[74,76]	0	hSpCas9	negative selection	1118963
90894427	90894450	14	-	26627737	RPE1	viability after 9 days	TGATGTTGGAGTGGTGCACAGGG	RPS6KA5	ENSG00000100784	-0.3294711752222964	[1220]	[315,288]	-2	hSpCas9	negative selection	1118964
90900707	90900730	14	+	26627737	RPE1	viability after 9 days	TAGGATGGAAGGAGCAACAAAGG	RPS6KA5	ENSG00000100784	-0.03306499455651002	[1602]	[355,663]	0	hSpCas9	negative selection	1118965
90923112	90923135	14	-	26627737	RPE1	viability after 9 days	GGGAGATTCAGGACATGACAAGG	RPS6KA5	ENSG00000100784	-0.29096163949644827	[338]	[53,128]	-2	hSpCas9	negative selection	1118966
90872076	90872099	14	+	26627737	RPE1	viability after 12 days	AAGCTACTGAGTCCGAGAACTGG	RPS6KA5	ENSG00000100784	0.32236106454939983	[1332]	[406,490]	2	hSpCas9	negative selection	1201276
90875294	90875317	14	-	26627737	RPE1	viability after 12 days	AAGTTTGACGTGTACCAGCGCGG	RPS6KA5	ENSG00000100784	0.7044022484795052	[1345]	[495,687]	4	hSpCas9	negative selection	1201277
90890600	90890623	14	-	26627737	RPE1	viability after 12 days	ATTTGCACGGCTAAAGCCACCGG	RPS6KA5	ENSG00000100784	0.21500648484749063	[233]	[105,37]	1	hSpCas9	negative selection	1201278
90894427	90894450	14	-	26627737	RPE1	viability after 12 days	TGATGTTGGAGTGGTGCACAGGG	RPS6KA5	ENSG00000100784	-0.48596281562445326	[1220]	[224,243]	-3	hSpCas9	negative selection	1201279
90900707	90900730	14	+	26627737	RPE1	viability after 12 days	TAGGATGGAAGGAGCAACAAAGG	RPS6KA5	ENSG00000100784	-0.025836002178762474	[1602]	[304,547]	0	hSpCas9	negative selection	1201280
90923112	90923135	14	-	26627737	RPE1	viability after 12 days	GGGAGATTCAGGACATGACAAGG	RPS6KA5	ENSG00000100784	-0.4441718295450372	[338]	[64,68]	-3	hSpCas9	negative selection	1201281
90872076	90872099	14	+	26627737	RPE1	viability after 15 days	AAGCTACTGAGTCCGAGAACTGG	RPS6KA5	ENSG00000100784	0.44447180824105115	[1332]	[561,465]	3	hSpCas9	negative selection	1283591
90875294	90875317	14	-	26627737	RPE1	viability after 15 days	AAGTTTGACGTGTACCAGCGCGG	RPS6KA5	ENSG00000100784	1.116967988589778	[1345]	[835,815]	6	hSpCas9	negative selection	1283592
90890600	90890623	14	-	26627737	RPE1	viability after 15 days	ATTTGCACGGCTAAAGCCACCGG	RPS6KA5	ENSG00000100784	-0.7869250719235099	[233]	[45,30]	-5	hSpCas9	negative selection	1283593
90894427	90894450	14	-	26627737	RPE1	viability after 15 days	TGATGTTGGAGTGGTGCACAGGG	RPS6KA5	ENSG00000100784	-0.36889877389721554	[1220]	[381,156]	-2	hSpCas9	negative selection	1283594
90900707	90900730	14	+	26627737	RPE1	viability after 15 days	TAGGATGGAAGGAGCAACAAAGG	RPS6KA5	ENSG00000100784	-0.05531600785302371	[1602]	[385,484]	0	hSpCas9	negative selection	1283595
90923112	90923135	14	-	26627737	RPE1	viability after 15 days	GGGAGATTCAGGACATGACAAGG	RPS6KA5	ENSG00000100784	0.757605406803015	[338]	[182,141]	5	hSpCas9	negative selection	1283596
90872076	90872099	14	+	26627737	RPE1	viability after 18 days	AAGCTACTGAGTCCGAGAACTGG	RPS6KA5	ENSG00000100784	0.5528111691461509	[1332]	[562,489]	3	hSpCas9	negative selection	1365906
90875294	90875317	14	-	26627737	RPE1	viability after 18 days	AAGTTTGACGTGTACCAGCGCGG	RPS6KA5	ENSG00000100784	0.6215919838700501	[1345]	[496,624]	4	hSpCas9	negative selection	1365907
90890600	90890623	14	-	26627737	RPE1	viability after 18 days	ATTTGCACGGCTAAAGCCACCGG	RPS6KA5	ENSG00000100784	-0.5612853758216265	[233]	[65,17]	-4	hSpCas9	negative selection	1365908
90894427	90894450	14	-	26627737	RPE1	viability after 18 days	TGATGTTGGAGTGGTGCACAGGG	RPS6KA5	ENSG00000100784	-0.03755804721232636	[1220]	[365,272]	0	hSpCas9	negative selection	1365909
90900707	90900730	14	+	26627737	RPE1	viability after 18 days	TAGGATGGAAGGAGCAACAAAGG	RPS6KA5	ENSG00000100784	-0.12093598330764477	[1602]	[304,496]	0	hSpCas9	negative selection	1365910
90923112	90923135	14	-	26627737	RPE1	viability after 18 days	GGGAGATTCAGGACATGACAAGG	RPS6KA5	ENSG00000100784	0.7395889379993461	[338]	[130,175]	4	hSpCas9	negative selection	1365911
90872076	90872099	14	+	26627737	HeLa	viability after 8 days	AAGCTACTGAGTCCGAGAACTGG	RPS6KA5	ENSG00000100784	-0.48612868291748434	[959]	[525,137,281]	-5	hSpCas9	negative selection	1448221
90875294	90875317	14	-	26627737	HeLa	viability after 8 days	AAGTTTGACGTGTACCAGCGCGG	RPS6KA5	ENSG00000100784	-0.4024681460290546	[627]	[308,130,202]	-4	hSpCas9	negative selection	1448222
90890600	90890623	14	-	26627737	HeLa	viability after 8 days	ATTTGCACGGCTAAAGCCACCGG	RPS6KA5	ENSG00000100784	0.7350782676518626	[104]	[99,65,67]	6	hSpCas9	negative selection	1448223
90894427	90894450	14	-	26627737	HeLa	viability after 8 days	TGATGTTGGAGTGGTGCACAGGG	RPS6KA5	ENSG00000100784	0.16728572246523984	[379]	[337,102,151]	1	hSpCas9	negative selection	1448224
90900707	90900730	14	+	26627737	HeLa	viability after 8 days	TAGGATGGAAGGAGCAACAAAGG	RPS6KA5	ENSG00000100784	-0.25558424936940555	[572]	[200,261,164]	-2	hSpCas9	negative selection	1448225
90923112	90923135	14	-	26627737	HeLa	viability after 8 days	GGGAGATTCAGGACATGACAAGG	RPS6KA5	ENSG00000100784	-0.4482462262285032	[395]	[252,104,53]	-4	hSpCas9	negative selection	1448226
90872076	90872099	14	+	26627737	HeLa	viability after 12 days	AAGCTACTGAGTCCGAGAACTGG	RPS6KA5	ENSG00000100784	-0.1703355526111825	[959]	[446,261,360]	-1	hSpCas9	negative selection	1530536
90875294	90875317	14	-	26627737	HeLa	viability after 12 days	AAGTTTGACGTGTACCAGCGCGG	RPS6KA5	ENSG00000100784	-0.12765030944306954	[627]	[240,206,267]	-1	hSpCas9	negative selection	1530537
90890600	90890623	14	-	26627737	HeLa	viability after 12 days	ATTTGCACGGCTAAAGCCACCGG	RPS6KA5	ENSG00000100784	0.47268452054614163	[104]	[30,29,121]	4	hSpCas9	negative selection	1530538
90894427	90894450	14	-	26627737	HeLa	viability after 12 days	TGATGTTGGAGTGGTGCACAGGG	RPS6KA5	ENSG00000100784	0.08747974486854515	[379]	[284,81,145]	0	hSpCas9	negative selection	1530539
90900707	90900730	14	+	26627737	HeLa	viability after 12 days	TAGGATGGAAGGAGCAACAAAGG	RPS6KA5	ENSG00000100784	-0.6113261027938698	[572]	[128,166,166]	-5	hSpCas9	negative selection	1530540
90923112	90923135	14	-	26627737	HeLa	viability after 12 days	GGGAGATTCAGGACATGACAAGG	RPS6KA5	ENSG00000100784	-1.07174258528975	[395]	[114,83,34]	-7	hSpCas9	negative selection	1530541
90872076	90872099	14	+	26627737	HeLa	viability after 15 days	AAGCTACTGAGTCCGAGAACTGG	RPS6KA5	ENSG00000100784	0.07744741230048335	[959]	[530,407,286]	0	hSpCas9	negative selection	1612851
90875294	90875317	14	-	26627737	HeLa	viability after 15 days	AAGTTTGACGTGTACCAGCGCGG	RPS6KA5	ENSG00000100784	0.0403048582200467	[627]	[340,143,305]	0	hSpCas9	negative selection	1612852
90890600	90890623	14	-	26627737	HeLa	viability after 15 days	ATTTGCACGGCTAAAGCCACCGG	RPS6KA5	ENSG00000100784	0.4274590156703191	[104]	[47,49,75]	3	hSpCas9	negative selection	1612853
90894427	90894450	14	-	26627737	HeLa	viability after 15 days	TGATGTTGGAGTGGTGCACAGGG	RPS6KA5	ENSG00000100784	0.5341822481115175	[379]	[221,190,261]	4	hSpCas9	negative selection	1612854
90900707	90900730	14	+	26627737	HeLa	viability after 15 days	TAGGATGGAAGGAGCAACAAAGG	RPS6KA5	ENSG00000100784	-0.4795765621637073	[572]	[187,165,145]	-4	hSpCas9	negative selection	1612855
90923112	90923135	14	-	26627737	HeLa	viability after 15 days	GGGAGATTCAGGACATGACAAGG	RPS6KA5	ENSG00000100784	-1.6811740787255482	[395]	[50,22,78]	-8	hSpCas9	negative selection	1612856
90872076	90872099	14	+	26627737	HeLa	viability after 18 days	AAGCTACTGAGTCCGAGAACTGG	RPS6KA5	ENSG00000100784	0.04883534976345394	[959]	[345,330,286]	0	hSpCas9	negative selection	1695166
90875294	90875317	14	-	26627737	HeLa	viability after 18 days	AAGTTTGACGTGTACCAGCGCGG	RPS6KA5	ENSG00000100784	-0.0002886621323762162	[627]	[217,114,305]	0	hSpCas9	negative selection	1695167
90890600	90890623	14	-	26627737	HeLa	viability after 18 days	ATTTGCACGGCTAAAGCCACCGG	RPS6KA5	ENSG00000100784	0.38653413881726917	[104]	[30,38,75]	3	hSpCas9	negative selection	1695168
90894427	90894450	14	-	26627737	HeLa	viability after 18 days	TGATGTTGGAGTGGTGCACAGGG	RPS6KA5	ENSG00000100784	0.5477679068710096	[379]	[145,166,261]	4	hSpCas9	negative selection	1695169
90900707	90900730	14	+	26627737	HeLa	viability after 18 days	TAGGATGGAAGGAGCAACAAAGG	RPS6KA5	ENSG00000100784	-0.46065443377912924	[572]	[129,137,145]	-4	hSpCas9	negative selection	1695170
90923112	90923135	14	-	26627737	HeLa	viability after 18 days	GGGAGATTCAGGACATGACAAGG	RPS6KA5	ENSG00000100784	-1.6043949920985288	[395]	[37,20,78]	-8	hSpCas9	negative selection	1695171
90872076	90872099	14	+	26627737	HCT116	viability after 6 days	AAGCTACTGAGTCCGAGAACTGG	RPS6KA5	ENSG00000100784	-1.459898746225709	[1460]	[194,21]	-7	hSpCas9	negative selection	1777481
90875294	90875317	14	-	26627737	HCT116	viability after 6 days	AAGTTTGACGTGTACCAGCGCGG	RPS6KA5	ENSG00000100784	0.8841417109222384	[913]	[134,336]	5	hSpCas9	negative selection	1777482
90890600	90890623	14	-	26627737	HCT116	viability after 6 days	ATTTGCACGGCTAAAGCCACCGG	RPS6KA5	ENSG00000100784	0.8433136958988482	[180]	[139,1]	4	hSpCas9	negative selection	1777483
90894427	90894450	14	-	26627737	HCT116	viability after 6 days	TGATGTTGGAGTGGTGCACAGGG	RPS6KA5	ENSG00000100784	1.1291619592967892	[664]	[218,233]	6	hSpCas9	negative selection	1777484
90900707	90900730	14	+	26627737	HCT116	viability after 6 days	TAGGATGGAAGGAGCAACAAAGG	RPS6KA5	ENSG00000100784	0.09957774572872953	[668]	[122,106]	0	hSpCas9	negative selection	1777485
90923112	90923135	14	-	26627737	HCT116	viability after 6 days	GGGAGATTCAGGACATGACAAGG	RPS6KA5	ENSG00000100784	-0.878056454407792	[497]	[59,32]	-5	hSpCas9	negative selection	1777486
90872076	90872099	14	+	26627737	HCT116	viability after 8 days	AAGCTACTGAGTCCGAGAACTGG	RPS6KA5	ENSG00000100784	-0.06618446706898684	[574]	[369,227,310]	0	hSpCas9	negative selection	1859796
90875294	90875317	14	-	26627737	HCT116	viability after 8 days	AAGTTTGACGTGTACCAGCGCGG	RPS6KA5	ENSG00000100784	-0.46808310423756067	[569]	[194,290,194]	-5	hSpCas9	negative selection	1859797
90890600	90890623	14	-	26627737	HCT116	viability after 8 days	ATTTGCACGGCTAAAGCCACCGG	RPS6KA5	ENSG00000100784	-0.2863213528360351	[53]	[21,13,36]	-3	hSpCas9	negative selection	1859798
90894427	90894450	14	-	26627737	HCT116	viability after 8 days	TGATGTTGGAGTGGTGCACAGGG	RPS6KA5	ENSG00000100784	0.04651285015140666	[324]	[209,217,127]	0	hSpCas9	negative selection	1859799
90900707	90900730	14	+	26627737	HCT116	viability after 8 days	TAGGATGGAAGGAGCAACAAAGG	RPS6KA5	ENSG00000100784	0.0703369275855929	[298]	[187,138,191]	0	hSpCas9	negative selection	1859800
90923112	90923135	14	-	26627737	HCT116	viability after 8 days	GGGAGATTCAGGACATGACAAGG	RPS6KA5	ENSG00000100784	0.31218260789103924	[166]	[126,102,112]	3	hSpCas9	negative selection	1859801
90872076	90872099	14	+	26627737	HCT116	viability after 9 days	AAGCTACTGAGTCCGAGAACTGG	RPS6KA5	ENSG00000100784	0.11974058470312565	[1460]	[281,535]	0	hSpCas9	negative selection	1942111
90875294	90875317	14	-	26627737	HCT116	viability after 9 days	AAGTTTGACGTGTACCAGCGCGG	RPS6KA5	ENSG00000100784	0.05670278377650129	[913]	[159,327]	0	hSpCas9	negative selection	1942112
90890600	90890623	14	-	26627737	HCT116	viability after 9 days	ATTTGCACGGCTAAAGCCACCGG	RPS6KA5	ENSG00000100784	-0.09035020111009007	[180]	[74,21]	0	hSpCas9	negative selection	1942113
90894427	90894450	14	-	26627737	HCT116	viability after 9 days	TGATGTTGGAGTGGTGCACAGGG	RPS6KA5	ENSG00000100784	-0.02279318961615641	[664]	[152,191]	0	hSpCas9	negative selection	1942114
90900707	90900730	14	+	26627737	HCT116	viability after 9 days	TAGGATGGAAGGAGCAACAAAGG	RPS6KA5	ENSG00000100784	-1.3819869247775352	[668]	[91,49]	-7	hSpCas9	negative selection	1942115
90923112	90923135	14	-	26627737	HCT116	viability after 9 days	GGGAGATTCAGGACATGACAAGG	RPS6KA5	ENSG00000100784	-0.38705352798168075	[497]	[56,136]	-3	hSpCas9	negative selection	1942116
90872076	90872099	14	+	26627737	HCT116	viability after 12 days	AAGCTACTGAGTCCGAGAACTGG	RPS6KA5	ENSG00000100784	0.2085735515766023	[574]	[285,427,340]	2	hSpCas9	negative selection	2024426
90875294	90875317	14	-	26627737	HCT116	viability after 12 days	AAGTTTGACGTGTACCAGCGCGG	RPS6KA5	ENSG00000100784	0.153427167207018	[569]	[346,321,328]	1	hSpCas9	negative selection	2024427
90890600	90890623	14	-	26627737	HCT116	viability after 12 days	ATTTGCACGGCTAAAGCCACCGG	RPS6KA5	ENSG00000100784	0.7661888824227177	[53]	[39,67,37]	6	hSpCas9	negative selection	2024428
90894427	90894450	14	-	26627737	HCT116	viability after 12 days	TGATGTTGGAGTGGTGCACAGGG	RPS6KA5	ENSG00000100784	0.5862557937989061	[324]	[292,253,218]	5	hSpCas9	negative selection	2024429
90900707	90900730	14	+	26627737	HCT116	viability after 12 days	TAGGATGGAAGGAGCAACAAAGG	RPS6KA5	ENSG00000100784	0.13792383015951473	[298]	[185,191,139]	1	hSpCas9	negative selection	2024430
90923112	90923135	14	-	26627737	HCT116	viability after 12 days	GGGAGATTCAGGACATGACAAGG	RPS6KA5	ENSG00000100784	0.5665059434927564	[166]	[158,114,112]	5	hSpCas9	negative selection	2024431
90872076	90872099	14	+	26627737	HCT116	viability after 15 days	AAGCTACTGAGTCCGAGAACTGG	RPS6KA5	ENSG00000100784	0.46031615279429006	[574]	[513,463,392]	4	hSpCas9	negative selection	2106741
90875294	90875317	14	-	26627737	HCT116	viability after 15 days	AAGTTTGACGTGTACCAGCGCGG	RPS6KA5	ENSG00000100784	-0.12957525111505197	[569]	[358,332,213]	-1	hSpCas9	negative selection	2106742
90890600	90890623	14	-	26627737	HCT116	viability after 15 days	ATTTGCACGGCTAAAGCCACCGG	RPS6KA5	ENSG00000100784	0.7326422554117422	[53]	[53,57,42]	6	hSpCas9	negative selection	2106743
90894427	90894450	14	-	26627737	HCT116	viability after 15 days	TGATGTTGGAGTGGTGCACAGGG	RPS6KA5	ENSG00000100784	-0.1366784156391961	[324]	[154,221,130]	-1	hSpCas9	negative selection	2106744
90900707	90900730	14	+	26627737	HCT116	viability after 15 days	TAGGATGGAAGGAGCAACAAAGG	RPS6KA5	ENSG00000100784	0.4751182808517791	[298]	[431,185,122]	4	hSpCas9	negative selection	2106745
90923112	90923135	14	-	26627737	HCT116	viability after 15 days	GGGAGATTCAGGACATGACAAGG	RPS6KA5	ENSG00000100784	0.342248617760052	[166]	[146,111,108]	3	hSpCas9	negative selection	2106746
90872076	90872099	14	+	26627737	HCT116	viability after 18 days	AAGCTACTGAGTCCGAGAACTGG	RPS6KA5	ENSG00000100784	0.07403580647240404	[574]	[186,488,183]	0	hSpCas9	negative selection	2189056
90875294	90875317	14	-	26627737	HCT116	viability after 18 days	AAGTTTGACGTGTACCAGCGCGG	RPS6KA5	ENSG00000100784	-0.137200175022969	[569]	[217,269,262]	-1	hSpCas9	negative selection	2189057
90890600	90890623	14	-	26627737	HCT116	viability after 18 days	ATTTGCACGGCTAAAGCCACCGG	RPS6KA5	ENSG00000100784	0.04028598217870227	[53]	[35,1,44]	0	hSpCas9	negative selection	2189058
90894427	90894450	14	-	26627737	HCT116	viability after 18 days	TGATGTTGGAGTGGTGCACAGGG	RPS6KA5	ENSG00000100784	0.5780799111436926	[324]	[153,204,351]	5	hSpCas9	negative selection	2189059
90900707	90900730	14	+	26627737	HCT116	viability after 18 days	TAGGATGGAAGGAGCAACAAAGG	RPS6KA5	ENSG00000100784	0.7596857895071546	[298]	[447,188,93]	6	hSpCas9	negative selection	2189060
90923112	90923135	14	-	26627737	HCT116	viability after 18 days	GGGAGATTCAGGACATGACAAGG	RPS6KA5	ENSG00000100784	0.12217751131387011	[166]	[130,83,46]	1	hSpCas9	negative selection	2189061
90978384	90978407	14	-	24336569	HL60	viability	AAGGACAGAACGACAAGTCCTGG	RPS6KA5	ENSG00000100784	-0.06083857990245356	[2013]	[4085]	0	hSpCas9	negative selection	2292998
90978397	90978420	14	+	24336569	HL60	viability	TTCTGTCCTTGTATGCTCTGTGG	RPS6KA5	ENSG00000100784	-0.8091667734661343	[206]	[249]	-6	hSpCas9	negative selection	2292999
90978465	90978488	14	+	24336569	HL60	viability	CATACAGCTTTCCAGTATCATGG	RPS6KA5	ENSG00000100784	0.07495339448512461	[929]	[2072]	0	hSpCas9	negative selection	2293000
91001079	91001102	14	+	24336569	HL60	viability	AAGACTTACCTCCAGTTCCTAGG	RPS6KA5	ENSG00000100784	0.5430267642788973	[971]	[2996]	5	hSpCas9	negative selection	2293001
91001087	91001110	14	-	24336569	HL60	viability	CTGAAGGTCCTAGGAACTGGAGG	RPS6KA5	ENSG00000100784	0.42599055466222735	[1025]	[2916]	4	hSpCas9	negative selection	2293002
91001096	91001119	14	-	24336569	HL60	viability	TTTGAGCTCCTGAAGGTCCTAGG	RPS6KA5	ENSG00000100784	0.05379572898157731	[350]	[770]	0	hSpCas9	negative selection	2293003
91001129	91001152	14	-	24336569	HL60	viability	ACAGGACATGCTGAGAAGGTGGG	RPS6KA5	ENSG00000100784	0.0812996876539378	[560]	[1255]	0	hSpCas9	negative selection	2293004
90978384	90978407	14	-	24336569	KBM7	viability	AAGGACAGAACGACAAGTCCTGG	RPS6KA5	ENSG00000100784	0.1289656106850643	[1546]	[4613]	1	hSpCas9	negative selection	2360175
90978397	90978420	14	+	24336569	KBM7	viability	TTCTGTCCTTGTATGCTCTGTGG	RPS6KA5	ENSG00000100784	0.3512137120052976	[168]	[587]	3	hSpCas9	negative selection	2360176
90978465	90978488	14	+	24336569	KBM7	viability	CATACAGCTTTCCAGTATCATGG	RPS6KA5	ENSG00000100784	0.8383590412832655	[689]	[3364]	7	hSpCas9	negative selection	2360177
91001079	91001102	14	+	24336569	KBM7	viability	AAGACTTACCTCCAGTTCCTAGG	RPS6KA5	ENSG00000100784	0.5205629588482519	[1075]	[4209]	5	hSpCas9	negative selection	2360178
91001087	91001110	14	-	24336569	KBM7	viability	CTGAAGGTCCTAGGAACTGGAGG	RPS6KA5	ENSG00000100784	0.5121310824254006	[1052]	[4095]	5	hSpCas9	negative selection	2360179
91001096	91001119	14	-	24336569	KBM7	viability	TTTGAGCTCCTGAAGGTCCTAGG	RPS6KA5	ENSG00000100784	-0.02953920910851532	[539]	[1442]	0	hSpCas9	negative selection	2360180
91001129	91001152	14	-	24336569	KBM7	viability	ACAGGACATGCTGAGAAGGTGGG	RPS6KA5	ENSG00000100784	-0.44013621336332054	[579]	[1165]	-4	hSpCas9	negative selection	2360181
90916676	90916699	14	-	25494202	A375	resistance to PLX-4720 (puromycin)	GTGTGTGTGTGTGTGTGTGACAG	RPS6KA5	ENSG00000100784	2.740144461675261	[44,53]	[104,38]	8	dCas9-VP64	positive selection	2402662
90997765	90997788	14	+	25494202	A375	resistance to PLX-4720 (puromycin)	CTTTGGGAGGCCAAGGCGGGCAG	RPS6KA5	ENSG00000100784	0.09588317305989913	[114,12]	[10,18]	0	dCas9-VP64	positive selection	2411115
91040294	91040317	14	+	25494202	A375	resistance to PLX-4720 (puromycin)	GCTACTTGGGAGGCTGAGGCCGG	RPS6KA5	ENSG00000100784	-0.3390870473927914	[36,5]	[4,0]	-1	dCas9-VP64	positive selection	2411813
90999122	90999145	14	+	25494202	A375	resistance to PLX-4720 (puromycin)	CACTTGAACCCAGGAGGCAGAAG	RPS6KA5	ENSG00000100784	-1.4184778160092897	[54,284]	[10,16]	-7	dCas9-VP64	positive selection	2414495
91051153	91051176	14	+	25494202	A375	resistance to PLX-4720 (puromycin)	CACTTGAACCCAGGAGGCAGTGG	RPS6KA5	ENSG00000100784	-1.4184778160092897	[54,284]	[10,16]	-7	dCas9-VP64	positive selection	2414602
90928027	90928050	14	-	25494202	A375	resistance to PLX-4720 (puromycin)	GCAAGAGGATCACTTGAGCCTGG	RPS6KA5	ENSG00000100784	0.169734143386715	[57,44]	[12,10]	0	dCas9-VP64	positive selection	2416887
90863046	90863069	14	+	25494202	A375	resistance to PLX-4720 (puromycin)	TGTAATCTCAGCACTTTGGGAGG	RPS6KA5	ENSG00000100784	0.15607651136927458	[32,6]	[6,1]	0	dCas9-VP64	positive selection	2438192
90882871	90882894	14	+	25494202	A375	resistance to PLX-4720 (puromycin)	CACTGCAACCTCCGCCTCCCAAG	RPS6KA5	ENSG00000100784	0.6259309833286419	[228,309]	[35,151]	2	dCas9-VP64	positive selection	2450427
90855680	90855703	14	+	25494202	A375	resistance to PLX-4720 (puromycin)	TCACTGCAAGCTCTGCCTCCTAG	RPS6KA5	ENSG00000100784	3.3241346106645673	[178,128]	[9,695]	8	dCas9-VP64	positive selection	2462028
91023355	91023378	14	-	25494202	A375	resistance to PLX-4720 (puromycin)	GAGGCAGAGGTTGCAGTGAGGAG	RPS6KA5	ENSG00000100784	2.8458860914044886	[4,6]	[4,13]	8	dCas9-VP64	positive selection	2464569
90944495	90944518	14	-	25494202	A375	resistance to PLX-4720 (puromycin)	TCCCAAAATGTTGGGATTACGGG	RPS6KA5	ENSG00000100784	-0.9779924112879362	[118,144]	[22,4]	-6	dCas9-VP64	positive selection	2469560
90914540	90914563	14	-	25494202	A375	resistance to PLX-4720 (puromycin)	CAGGTGGATCACCTGAAGTCAAG	RPS6KA5	ENSG00000100784	-1.080501538256204	[504,81]	[37,20]	-6	dCas9-VP64	positive selection	2472768
91014298	91014321	14	+	25494202	A375	resistance to PLX-4720 (puromycin)	CGAGACCATCCTAGCCAACACGG	RPS6KA5	ENSG00000100784	0.13192249624084318	[146,169]	[41,33]	0	dCas9-VP64	positive selection	2475610
91028556	91028579	14	+	25494202	A375	resistance to PLX-4720 (puromycin)	TCGCCCAGGCTGGAGTGCAGAGG	RPS6KA5	ENSG00000100784	0.5070772209909733	[97,61]	[39,7]	2	dCas9-VP64	positive selection	2477699
90916676	90916699	14	-	25494202	A375	resistance to PLX-4720 (zeocin)	GTGTGTGTGTGTGTGTGTGACAG	RPS6KA5	ENSG00000100784	-0.0021690128549880505	[109,77]	[41,19]	0	dCas9-VP64	positive selection	2497917
90997765	90997788	14	+	25494202	A375	resistance to PLX-4720 (zeocin)	CTTTGGGAGGCCAAGGCGGGCAG	RPS6KA5	ENSG00000100784	3.077269363618506	[19,18]	[13,93]	9	dCas9-VP64	positive selection	2506370
91040294	91040317	14	+	25494202	A375	resistance to PLX-4720 (zeocin)	GCTACTTGGGAGGCTGAGGCCGG	RPS6KA5	ENSG00000100784	0.46536086309934765	[31,100]	[53,5]	3	dCas9-VP64	positive selection	2507068
90999122	90999145	14	+	25494202	A375	resistance to PLX-4720 (zeocin)	CACTTGAACCCAGGAGGCAGAAG	RPS6KA5	ENSG00000100784	0.5761613238144463	[143,285]	[83,121]	4	dCas9-VP64	positive selection	2509750
91051153	91051176	14	+	25494202	A375	resistance to PLX-4720 (zeocin)	CACTTGAACCCAGGAGGCAGTGG	RPS6KA5	ENSG00000100784	0.5761613238144463	[143,285]	[83,121]	4	dCas9-VP64	positive selection	2509857
90928027	90928050	14	-	25494202	A375	resistance to PLX-4720 (zeocin)	GCAAGAGGATCACTTGAGCCTGG	RPS6KA5	ENSG00000100784	-0.04478500742304492	[42,58]	[7,21]	0	dCas9-VP64	positive selection	2512142
90863046	90863069	14	+	25494202	A375	resistance to PLX-4720 (zeocin)	TGTAATCTCAGCACTTTGGGAGG	RPS6KA5	ENSG00000100784	-0.09854114350347812	[128,153]	[28,55]	-1	dCas9-VP64	positive selection	2533447
90882871	90882894	14	+	25494202	A375	resistance to PLX-4720 (zeocin)	CACTGCAACCTCCGCCTCCCAAG	RPS6KA5	ENSG00000100784	0.8832307312434098	[227,267]	[69,222]	6	dCas9-VP64	positive selection	2545682
90855680	90855703	14	+	25494202	A375	resistance to PLX-4720 (zeocin)	TCACTGCAAGCTCTGCCTCCTAG	RPS6KA5	ENSG00000100784	-0.24751078726835885	[128,142]	[21,50]	-2	dCas9-VP64	positive selection	2557283
91023355	91023378	14	-	25494202	A375	resistance to PLX-4720 (zeocin)	GAGGCAGAGGTTGCAGTGAGGAG	RPS6KA5	ENSG00000100784	0.5694698539005818	[43,11]	[11,14]	4	dCas9-VP64	positive selection	2559824
90944495	90944518	14	-	25494202	A375	resistance to PLX-4720 (zeocin)	TCCCAAAATGTTGGGATTACGGG	RPS6KA5	ENSG00000100784	0.3469774473649052	[51,34]	[26,8]	3	dCas9-VP64	positive selection	2564815
90914540	90914563	14	-	25494202	A375	resistance to PLX-4720 (zeocin)	CAGGTGGATCACCTGAAGTCAAG	RPS6KA5	ENSG00000100784	0.09148827261213754	[58,380]	[33,114]	0	dCas9-VP64	positive selection	2568023
91014298	91014321	14	+	25494202	A375	resistance to PLX-4720 (zeocin)	CGAGACCATCCTAGCCAACACGG	RPS6KA5	ENSG00000100784	1.169571951725572	[51,120]	[60,65]	7	dCas9-VP64	positive selection	2570865
91028556	91028579	14	+	25494202	A375	resistance to PLX-4720 (zeocin)	TCGCCCAGGCTGGAGTGCAGAGG	RPS6KA5	ENSG00000100784	-0.06949214303462026	[365,454]	[80,170]	0	dCas9-VP64	positive selection	2572954
90978465	90978488	14	+	27260157	DLD1	viability	CATACAGCTTTCCAGTATCATGG	RPS6KA5	ENSG00000100784	0.587231105203055	[]	[]	8	hSpCas9	negative selection	2574811
90900645	90900668	14	-	27260157	DLD1	viability	CACATGGGAGTTGAACGTCCTGG	RPS6KA5	ENSG00000100784	0.809363947443967	[]	[]	9	hSpCas9	negative selection	2576121
90894427	90894450	14	-	27260157	DLD1	viability	TGATGTTGGAGTGGTGCACAGGG	RPS6KA5	ENSG00000100784	0.722989995697297	[]	[]	8	hSpCas9	negative selection	2576877
90900626	90900649	14	-	27260157	DLD1	viability	CTGGAGTGACAAATGTTGCCAGG	RPS6KA5	ENSG00000100784	1.4723184886162	[]	[]	9	hSpCas9	negative selection	2579309
90900608	90900631	14	+	27260157	DLD1	viability	TACCTTCATCATTGCACTCCTGG	RPS6KA5	ENSG00000100784	0.726171027610324	[]	[]	8	hSpCas9	negative selection	2582296
90978384	90978407	14	-	27260157	DLD1	viability	AAGGACAGAACGACAAGTCCTGG	RPS6KA5	ENSG00000100784	0.897101051205454	[]	[]	9	hSpCas9	negative selection	2583278
90894194	90894217	14	-	27260157	DLD1	viability	TTTGCCAGCTGATCATCTTGAGG	RPS6KA5	ENSG00000100784	0.203088887689334	[]	[]	3	hSpCas9	negative selection	2587292
90978397	90978420	14	+	27260157	DLD1	viability	TTCTGTCCTTGTATGCTCTGTGG	RPS6KA5	ENSG00000100784	0.0849004352467738	[]	[]	3	hSpCas9	negative selection	2604766
90900688	90900711	14	+	27260157	DLD1	viability	CAGCTGCATTACGCTTGAATAGG	RPS6KA5	ENSG00000100784	-0.526756999268573	[]	[]	-4	hSpCas9	negative selection	2608116
90978366	90978389	14	+	27260157	DLD1	viability	GCGACTGCCTAATGTGTTCCAGG	RPS6KA5	ENSG00000100784	0.560719925285835	[]	[]	8	hSpCas9	negative selection	2613140
90890600	90890623	14	-	27260157	DLD1	viability	ATTTGCACGGCTAAAGCCACCGG	RPS6KA5	ENSG00000100784	0.766105475728671	[]	[]	8	hSpCas9	negative selection	2616492
91001129	91001152	14	-	27260157	DLD1	viability	ACAGGACATGCTGAGAAGGTGGG	RPS6KA5	ENSG00000100784	0.312089018380244	[]	[]	4	hSpCas9	negative selection	2617112
91001096	91001119	14	-	27260157	DLD1	viability	TTTGAGCTCCTGAAGGTCCTAGG	RPS6KA5	ENSG00000100784	0.919597934349533	[]	[]	9	hSpCas9	negative selection	2618693
90894479	90894502	14	-	27260157	DLD1	viability	CGGAAGCCAGCTACATCATGAGG	RPS6KA5	ENSG00000100784	-0.251078045140627	[]	[]	-2	hSpCas9	negative selection	2619312
91001087	91001110	14	-	27260157	DLD1	viability	CTGAAGGTCCTAGGAACTGGAGG	RPS6KA5	ENSG00000100784	0.143326123205012	[]	[]	3	hSpCas9	negative selection	2621913
90894546	90894569	14	-	27260157	DLD1	viability	GTGATGGAACTTCTGAATGGAGG	RPS6KA5	ENSG00000100784	-0.0776970388971505	[]	[]	0	hSpCas9	negative selection	2622039
91001079	91001102	14	+	27260157	DLD1	viability	AAGACTTACCTCCAGTTCCTAGG	RPS6KA5	ENSG00000100784	1.64456418910746	[]	[]	9	hSpCas9	negative selection	2647629
90978465	90978488	14	+	27260157	HT1080	viability	CATACAGCTTTCCAGTATCATGG	RPS6KA5	ENSG00000100784	0.574656779982379	[]	[]	5	hSpCas9	negative selection	2650941
90900645	90900668	14	-	27260157	HT1080	viability	CACATGGGAGTTGAACGTCCTGG	RPS6KA5	ENSG00000100784	0.187958889991613	[]	[]	1	hSpCas9	negative selection	2652251
90894427	90894450	14	-	27260157	HT1080	viability	TGATGTTGGAGTGGTGCACAGGG	RPS6KA5	ENSG00000100784	0.411365308969291	[]	[]	4	hSpCas9	negative selection	2653007
90900626	90900649	14	-	27260157	HT1080	viability	CTGGAGTGACAAATGTTGCCAGG	RPS6KA5	ENSG00000100784	1.13713631345434	[]	[]	8	hSpCas9	negative selection	2655439
90900608	90900631	14	+	27260157	HT1080	viability	TACCTTCATCATTGCACTCCTGG	RPS6KA5	ENSG00000100784	0.168330251166886	[]	[]	1	hSpCas9	negative selection	2658426
90978384	90978407	14	-	27260157	HT1080	viability	AAGGACAGAACGACAAGTCCTGG	RPS6KA5	ENSG00000100784	0.183818035896428	[]	[]	1	hSpCas9	negative selection	2659408
90894194	90894217	14	-	27260157	HT1080	viability	TTTGCCAGCTGATCATCTTGAGG	RPS6KA5	ENSG00000100784	0.430201769603958	[]	[]	4	hSpCas9	negative selection	2663422
90978397	90978420	14	+	27260157	HT1080	viability	TTCTGTCCTTGTATGCTCTGTGG	RPS6KA5	ENSG00000100784	-0.240016611609028	[]	[]	0	hSpCas9	negative selection	2680896
90900688	90900711	14	+	27260157	HT1080	viability	CAGCTGCATTACGCTTGAATAGG	RPS6KA5	ENSG00000100784	-0.222347690690321	[]	[]	0	hSpCas9	negative selection	2684246
90978366	90978389	14	+	27260157	HT1080	viability	GCGACTGCCTAATGTGTTCCAGG	RPS6KA5	ENSG00000100784	1.16313022690546	[]	[]	8	hSpCas9	negative selection	2689270
90890600	90890623	14	-	27260157	HT1080	viability	ATTTGCACGGCTAAAGCCACCGG	RPS6KA5	ENSG00000100784	0.530698650117617	[]	[]	5	hSpCas9	negative selection	2692622
91001129	91001152	14	-	27260157	HT1080	viability	ACAGGACATGCTGAGAAGGTGGG	RPS6KA5	ENSG00000100784	0.15802424516857	[]	[]	1	hSpCas9	negative selection	2693242
91001096	91001119	14	-	27260157	HT1080	viability	TTTGAGCTCCTGAAGGTCCTAGG	RPS6KA5	ENSG00000100784	1.23688245303464	[]	[]	8	hSpCas9	negative selection	2694823
90894479	90894502	14	-	27260157	HT1080	viability	CGGAAGCCAGCTACATCATGAGG	RPS6KA5	ENSG00000100784	0.381789503339632	[]	[]	3	hSpCas9	negative selection	2695442
91001087	91001110	14	-	27260157	HT1080	viability	CTGAAGGTCCTAGGAACTGGAGG	RPS6KA5	ENSG00000100784	0.156079060875052	[]	[]	1	hSpCas9	negative selection	2698043
90894546	90894569	14	-	27260157	HT1080	viability	GTGATGGAACTTCTGAATGGAGG	RPS6KA5	ENSG00000100784	0.428791963999222	[]	[]	4	hSpCas9	negative selection	2698169
91001079	91001102	14	+	27260157	HT1080	viability	AAGACTTACCTCCAGTTCCTAGG	RPS6KA5	ENSG00000100784	1.63700884696321	[]	[]	9	hSpCas9	negative selection	2723759
90978465	90978488	14	+	27260157	MKN45	viability	CATACAGCTTTCCAGTATCATGG	RPS6KA5	ENSG00000100784	1.10587191978911	[]	[]	8	hSpCas9	negative selection	2727071
90900645	90900668	14	-	27260157	MKN45	viability	CACATGGGAGTTGAACGTCCTGG	RPS6KA5	ENSG00000100784	0.1623616363454	[]	[]	5	hSpCas9	negative selection	2728381
90894427	90894450	14	-	27260157	MKN45	viability	TGATGTTGGAGTGGTGCACAGGG	RPS6KA5	ENSG00000100784	0.378635398110471	[]	[]	6	hSpCas9	negative selection	2729137
90900626	90900649	14	-	27260157	MKN45	viability	CTGGAGTGACAAATGTTGCCAGG	RPS6KA5	ENSG00000100784	1.14043708777012	[]	[]	8	hSpCas9	negative selection	2731569
90900608	90900631	14	+	27260157	MKN45	viability	TACCTTCATCATTGCACTCCTGG	RPS6KA5	ENSG00000100784	-0.136490050123423	[]	[]	0	hSpCas9	negative selection	2734556
90978384	90978407	14	-	27260157	MKN45	viability	AAGGACAGAACGACAAGTCCTGG	RPS6KA5	ENSG00000100784	0.927903045036286	[]	[]	8	hSpCas9	negative selection	2735538
90894194	90894217	14	-	27260157	MKN45	viability	TTTGCCAGCTGATCATCTTGAGG	RPS6KA5	ENSG00000100784	1.45032905470799	[]	[]	9	hSpCas9	negative selection	2739552
90978397	90978420	14	+	27260157	MKN45	viability	TTCTGTCCTTGTATGCTCTGTGG	RPS6KA5	ENSG00000100784	0.830886676656633	[]	[]	8	hSpCas9	negative selection	2757026
90900688	90900711	14	+	27260157	MKN45	viability	CAGCTGCATTACGCTTGAATAGG	RPS6KA5	ENSG00000100784	-0.245152707198524	[]	[]	-1	hSpCas9	negative selection	2760376
90978366	90978389	14	+	27260157	MKN45	viability	GCGACTGCCTAATGTGTTCCAGG	RPS6KA5	ENSG00000100784	0.275103384417967	[]	[]	5	hSpCas9	negative selection	2765400
90890600	90890623	14	-	27260157	MKN45	viability	ATTTGCACGGCTAAAGCCACCGG	RPS6KA5	ENSG00000100784	0.17704883618743	[]	[]	5	hSpCas9	negative selection	2768752
91001129	91001152	14	-	27260157	MKN45	viability	ACAGGACATGCTGAGAAGGTGGG	RPS6KA5	ENSG00000100784	1.38869354675173	[]	[]	9	hSpCas9	negative selection	2769372
91001096	91001119	14	-	27260157	MKN45	viability	TTTGAGCTCCTGAAGGTCCTAGG	RPS6KA5	ENSG00000100784	0.754198850288862	[]	[]	7	hSpCas9	negative selection	2770953
90894479	90894502	14	-	27260157	MKN45	viability	CGGAAGCCAGCTACATCATGAGG	RPS6KA5	ENSG00000100784	0.997019620888698	[]	[]	8	hSpCas9	negative selection	2771572
91001087	91001110	14	-	27260157	MKN45	viability	CTGAAGGTCCTAGGAACTGGAGG	RPS6KA5	ENSG00000100784	0.981170235691447	[]	[]	8	hSpCas9	negative selection	2774173
90894546	90894569	14	-	27260157	MKN45	viability	GTGATGGAACTTCTGAATGGAGG	RPS6KA5	ENSG00000100784	1.2889366206639	[]	[]	9	hSpCas9	negative selection	2774299
91001079	91001102	14	+	27260157	MKN45	viability	AAGACTTACCTCCAGTTCCTAGG	RPS6KA5	ENSG00000100784	0.644996182867842	[]	[]	7	hSpCas9	negative selection	2799889
90978465	90978488	14	+	27260157	RKO	viability	CATACAGCTTTCCAGTATCATGG	RPS6KA5	ENSG00000100784	-0.226041103523773	[]	[]	-1	hSpCas9	negative selection	2803201
90900645	90900668	14	-	27260157	RKO	viability	CACATGGGAGTTGAACGTCCTGG	RPS6KA5	ENSG00000100784	1.01204434283306	[]	[]	9	hSpCas9	negative selection	2804511
90894427	90894450	14	-	27260157	RKO	viability	TGATGTTGGAGTGGTGCACAGGG	RPS6KA5	ENSG00000100784	0.561465600814981	[]	[]	3	hSpCas9	negative selection	2805267
90900626	90900649	14	-	27260157	RKO	viability	CTGGAGTGACAAATGTTGCCAGG	RPS6KA5	ENSG00000100784	1.21383043327233	[]	[]	9	hSpCas9	negative selection	2807699
90900608	90900631	14	+	27260157	RKO	viability	TACCTTCATCATTGCACTCCTGG	RPS6KA5	ENSG00000100784	-0.264195912701152	[]	[]	-1	hSpCas9	negative selection	2810686
90978384	90978407	14	-	27260157	RKO	viability	AAGGACAGAACGACAAGTCCTGG	RPS6KA5	ENSG00000100784	0.618059267910896	[]	[]	3	hSpCas9	negative selection	2811668
90894194	90894217	14	-	27260157	RKO	viability	TTTGCCAGCTGATCATCTTGAGG	RPS6KA5	ENSG00000100784	0.345695523605914	[]	[]	1	hSpCas9	negative selection	2815682
90978397	90978420	14	+	27260157	RKO	viability	TTCTGTCCTTGTATGCTCTGTGG	RPS6KA5	ENSG00000100784	0.226532769060236	[]	[]	1	hSpCas9	negative selection	2833156
90900688	90900711	14	+	27260157	RKO	viability	CAGCTGCATTACGCTTGAATAGG	RPS6KA5	ENSG00000100784	-1.33001243501067	[]	[]	-8	hSpCas9	negative selection	2836506
90978366	90978389	14	+	27260157	RKO	viability	GCGACTGCCTAATGTGTTCCAGG	RPS6KA5	ENSG00000100784	0.0681640594975273	[]	[]	0	hSpCas9	negative selection	2841530
90890600	90890623	14	-	27260157	RKO	viability	ATTTGCACGGCTAAAGCCACCGG	RPS6KA5	ENSG00000100784	0.0860006838329044	[]	[]	0	hSpCas9	negative selection	2844882
91001129	91001152	14	-	27260157	RKO	viability	ACAGGACATGCTGAGAAGGTGGG	RPS6KA5	ENSG00000100784	0.1276323762126	[]	[]	0	hSpCas9	negative selection	2845502
91001096	91001119	14	-	27260157	RKO	viability	TTTGAGCTCCTGAAGGTCCTAGG	RPS6KA5	ENSG00000100784	1.13796192858924	[]	[]	9	hSpCas9	negative selection	2847083
90894479	90894502	14	-	27260157	RKO	viability	CGGAAGCCAGCTACATCATGAGG	RPS6KA5	ENSG00000100784	0.205473327424002	[]	[]	1	hSpCas9	negative selection	2847702
91001087	91001110	14	-	27260157	RKO	viability	CTGAAGGTCCTAGGAACTGGAGG	RPS6KA5	ENSG00000100784	-0.158135201886051	[]	[]	0	hSpCas9	negative selection	2850303
90894546	90894569	14	-	27260157	RKO	viability	GTGATGGAACTTCTGAATGGAGG	RPS6KA5	ENSG00000100784	-0.104171607521128	[]	[]	0	hSpCas9	negative selection	2850429
91001079	91001102	14	+	27260157	RKO	viability	AAGACTTACCTCCAGTTCCTAGG	RPS6KA5	ENSG00000100784	1.40484683308652	[]	[]	9	hSpCas9	negative selection	2876019
90978465	90978488	14	+	27260157	SF268	viability	CATACAGCTTTCCAGTATCATGG	RPS6KA5	ENSG00000100784	-0.00676794722444666	[]	[]	0	hSpCas9	negative selection	2879331
90900645	90900668	14	-	27260157	SF268	viability	CACATGGGAGTTGAACGTCCTGG	RPS6KA5	ENSG00000100784	0.288220294428759	[]	[]	4	hSpCas9	negative selection	2880641
90894427	90894450	14	-	27260157	SF268	viability	TGATGTTGGAGTGGTGCACAGGG	RPS6KA5	ENSG00000100784	0.358394038932545	[]	[]	4	hSpCas9	negative selection	2881397
90900626	90900649	14	-	27260157	SF268	viability	CTGGAGTGACAAATGTTGCCAGG	RPS6KA5	ENSG00000100784	1.24785959526315	[]	[]	9	hSpCas9	negative selection	2883829
90900608	90900631	14	+	27260157	SF268	viability	TACCTTCATCATTGCACTCCTGG	RPS6KA5	ENSG00000100784	0.678477425810141	[]	[]	8	hSpCas9	negative selection	2886816
90978384	90978407	14	-	27260157	SF268	viability	AAGGACAGAACGACAAGTCCTGG	RPS6KA5	ENSG00000100784	0.922188978032813	[]	[]	9	hSpCas9	negative selection	2887798
90894194	90894217	14	-	27260157	SF268	viability	TTTGCCAGCTGATCATCTTGAGG	RPS6KA5	ENSG00000100784	0.663918784496796	[]	[]	8	hSpCas9	negative selection	2891812
90978397	90978420	14	+	27260157	SF268	viability	TTCTGTCCTTGTATGCTCTGTGG	RPS6KA5	ENSG00000100784	-0.0605646614965684	[]	[]	0	hSpCas9	negative selection	2909286
90900688	90900711	14	+	27260157	SF268	viability	CAGCTGCATTACGCTTGAATAGG	RPS6KA5	ENSG00000100784	0.355629202254126	[]	[]	4	hSpCas9	negative selection	2912636
90978366	90978389	14	+	27260157	SF268	viability	GCGACTGCCTAATGTGTTCCAGG	RPS6KA5	ENSG00000100784	0.292705112039304	[]	[]	4	hSpCas9	negative selection	2917660
90890600	90890623	14	-	27260157	SF268	viability	ATTTGCACGGCTAAAGCCACCGG	RPS6KA5	ENSG00000100784	0.760959924721423	[]	[]	8	hSpCas9	negative selection	2921012
91001129	91001152	14	-	27260157	SF268	viability	ACAGGACATGCTGAGAAGGTGGG	RPS6KA5	ENSG00000100784	0.713790213410204	[]	[]	8	hSpCas9	negative selection	2921632
91001096	91001119	14	-	27260157	SF268	viability	TTTGAGCTCCTGAAGGTCCTAGG	RPS6KA5	ENSG00000100784	1.10411555639894	[]	[]	9	hSpCas9	negative selection	2923213
90894479	90894502	14	-	27260157	SF268	viability	CGGAAGCCAGCTACATCATGAGG	RPS6KA5	ENSG00000100784	0.105627317212397	[]	[]	0	hSpCas9	negative selection	2923832
91001087	91001110	14	-	27260157	SF268	viability	CTGAAGGTCCTAGGAACTGGAGG	RPS6KA5	ENSG00000100784	0.228878912617228	[]	[]	3	hSpCas9	negative selection	2926433
90894546	90894569	14	-	27260157	SF268	viability	GTGATGGAACTTCTGAATGGAGG	RPS6KA5	ENSG00000100784	0.495579596273234	[]	[]	7	hSpCas9	negative selection	2926559
91001079	91001102	14	+	27260157	SF268	viability	AAGACTTACCTCCAGTTCCTAGG	RPS6KA5	ENSG00000100784	1.43112537420189	[]	[]	9	hSpCas9	negative selection	2952149
90947433	90947456	14	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TACCTTGTGGAGATGTTCGAGGG	RPS6KA5	ENSG00000100784	0.35902887116672083	[3,3]	[4,3]	7	hSpCas9	positive selection	3017986
90947434	90947457	14	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TGCCCTCGAACATCTCCACAAGG	RPS6KA5	ENSG00000100784	0.2490823281217407	[5,5]	[6,5]	5	hSpCas9	positive selection	3017987
90947433	90947456	14	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TACCTTGTGGAGATGTTCGAGGG	RPS6KA5	ENSG00000100784	0.38397718502965117	[3,3]	[3,2]	6	hSpCas9	positive selection	3085844
90947434	90947457	14	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TGCCCTCGAACATCTCCACAAGG	RPS6KA5	ENSG00000100784	0.09405725684357491	[5,5]	[5,3]	1	hSpCas9	positive selection	3085845
91001079	91001102		+	24336571	A375	resistance to PLX after 7 days	AAGACTTACCTCCAGTTCCTAGG	RPS6KA5	ENSG00000100784	-0.16086382704912072	[42,36]	[36,33]	-5	hSpCas9	positive selection	3141902
90978304	90978327		+	24336571	A375	resistance to PLX after 7 days	ACCTAAAATGAGATGAAGTTTGG	RPS6KA5	ENSG00000100784	-0.04823624785410881	[11,11]	[10,11]	-1	hSpCas9	positive selection	3141903
91001103	91001126		-	24336571	A375	resistance to PLX after 7 days	AGAAAATTTTGAGCTCCTGAAGG	RPS6KA5	ENSG00000100784	-0.30995685862624245	[4,6]	[4,4]	-8	hSpCas9	positive selection	3141904
91001079	91001102		+	24336571	A375	resistance to PLX after 14 days	AAGACTTACCTCCAGTTCCTAGG	RPS6KA5	ENSG00000100784	-0.6194470635378466	[48,31]	[9,13]	-7	hSpCas9	positive selection	3199695
90978304	90978327		+	24336571	A375	resistance to PLX after 14 days	ACCTAAAATGAGATGAAGTTTGG	RPS6KA5	ENSG00000100784	0.316030166030216	[11,14]	[5,8]	3	hSpCas9	positive selection	3199696
91001103	91001126		-	24336571	A375	resistance to PLX after 14 days	AGAAAATTTTGAGCTCCTGAAGG	RPS6KA5	ENSG00000100784	-0.4238906290570158	[6,8]	[2,1]	-5	hSpCas9	positive selection	3199697
91001079	91001102		+	24336571	A375	viability after 7 days	AAGACTTACCTCCAGTTCCTAGG	RPS6KA5	ENSG00000100784	0.010867547445425174	[41]	[42,36]	0	hSpCas9	negative selection	3257488
90978304	90978327		+	24336571	A375	viability after 7 days	ACCTAAAATGAGATGAAGTTTGG	RPS6KA5	ENSG00000100784	-0.19802125562887882	[14]	[11,11]	-3	hSpCas9	negative selection	3257489
91001103	91001126		-	24336571	A375	viability after 7 days	AGAAAATTTTGAGCTCCTGAAGG	RPS6KA5	ENSG00000100784	-0.7087008058455004	[10]	[4,6]	-7	hSpCas9	negative selection	3257490
91001079	91001102		+	24336571	A375	viability after 14 days	AAGACTTACCTCCAGTTCCTAGG	RPS6KA5	ENSG00000100784	0.034273844388531316	[41]	[48,31]	0	hSpCas9	negative selection	3315281
90978304	90978327		+	24336571	A375	viability after 14 days	ACCTAAAATGAGATGAAGTTTGG	RPS6KA5	ENSG00000100784	-0.002998555281838955	[14]	[11,14]	0	hSpCas9	negative selection	3315282
91001103	91001126		-	24336571	A375	viability after 14 days	AGAAAATTTTGAGCTCCTGAAGG	RPS6KA5	ENSG00000100784	-0.319647870675347	[10]	[6,8]	-4	hSpCas9	negative selection	3315283
90978397	90978420	14	+	27383988	293T	resistance to West Nile virus (flavivirus)	TTCTGTCCTTGTATGCTCTGTGG	RPS6KA5	ENSG00000100784	-1.1980010088587256	[350,350]	[0,0]	-7	hSpCas9	positive selection	3390676
91001079	91001102	14	+	27383988	293T	resistance to West Nile virus (flavivirus)	AAGACTTACCTCCAGTTCCTAGG	RPS6KA5	ENSG00000100784	-2.0211232467746463	[620,620]	[0,0]	-9	hSpCas9	positive selection	3390677
90978304	90978327	14	+	27383988	293T	resistance to West Nile virus (flavivirus)	ACCTAAAATGAGATGAAGTTTGG	RPS6KA5	ENSG00000100784	2.00939869800225	[37,37]	[0,0]	7	hSpCas9	positive selection	3390678
90947432	90947455	14	+	26780180	HT29	viability (Avana library 4 designs)	TACCTTGTGGAGATGTTCGAGGG	RPS6KA5	ENSG00000100784	0.634507800543827	[]	[]	2	hSpCas9	negative selection	3456367
90947434	90947457	14	-	26780180	HT29	viability (Avana library 4 designs)	TGCCCTCGAACATCTCCACAAGG	RPS6KA5	ENSG00000100784	-0.185125148060714	[]	[]	-3	hSpCas9	negative selection	3456368
90947432	90947455	14	+	26780180	A375	viability (Avana lentiCRISPRv2)	TACCTTGTGGAGATGTTCGAGGG	RPS6KA5	ENSG00000100784	2.21921037714523	[]	[]	3	hSpCas9	negative selection	3554810
90947434	90947457	14	-	26780180	A375	viability (Avana lentiCRISPRv2)	TGCCCTCGAACATCTCCACAAGG	RPS6KA5	ENSG00000100784	0.972789662488782	[]	[]	1	hSpCas9	negative selection	3554811
91001087	91001110	14	-	26780180	A375	viability (Avana lentiCRISPRv2)	CTGAAGGTCCTAGGAACTGGAGG	RPS6KA5	ENSG00000100784	3.81410316366295	[]	[]	6	hSpCas9	negative selection	3554812
90923134	90923157	14	-	26780180	A375	viability (Avana lentiCRISPRv2)	TGGCACCAGATATTGTCAGAGGG	RPS6KA5	ENSG00000100784	3.25359031308342	[]	[]	5	hSpCas9	negative selection	3554813
90947432	90947455	14	+	26780180	A375	viability (Avana lentiGuide)	TACCTTGTGGAGATGTTCGAGGG	RPS6KA5	ENSG00000100784	-1.75029799865152	[]	[]	-3	hSpCas9	negative selection	3663469
90947434	90947457	14	-	26780180	A375	viability (Avana lentiGuide)	TGCCCTCGAACATCTCCACAAGG	RPS6KA5	ENSG00000100784	-4.95028237498229	[]	[]	-8	hSpCas9	negative selection	3663470
91001087	91001110	14	-	26780180	A375	viability (Avana lentiGuide)	CTGAAGGTCCTAGGAACTGGAGG	RPS6KA5	ENSG00000100784	-4.79818099548363	[]	[]	-7	hSpCas9	negative selection	3663471
90923134	90923157	14	-	26780180	A375	viability (Avana lentiGuide)	TGGCACCAGATATTGTCAGAGGG	RPS6KA5	ENSG00000100784	-1.57445328394295	[]	[]	-3	hSpCas9	negative selection	3663472
90947432	90947455	14	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TACCTTGTGGAGATGTTCGAGGG	RPS6KA5	ENSG00000100784	-0.012659901872877632	[6]	[5,5]	0	hSpCas9	positive selection	3772076
90947434	90947457	14	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TGCCCTCGAACATCTCCACAAGG	RPS6KA5	ENSG00000100784	0.09501400102336682	[6]	[6,6]	2	hSpCas9	positive selection	3772077
91001087	91001110	14	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CTGAAGGTCCTAGGAACTGGAGG	RPS6KA5	ENSG00000100784	0.2604422711581824	[6]	[7,7]	7	hSpCas9	positive selection	3772078
90923134	90923157	14	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TGGCACCAGATATTGTCAGAGGG	RPS6KA5	ENSG00000100784	0.015770128260552536	[4]	[4,4]	0	hSpCas9	positive selection	3772079
90947432	90947455	14	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TACCTTGTGGAGATGTTCGAGGG	RPS6KA5	ENSG00000100784	0.12063672541492251	[5]	[5,5]	2	hSpCas9	positive selection	3880683
90947434	90947457	14	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TGCCCTCGAACATCTCCACAAGG	RPS6KA5	ENSG00000100784	0.32765648022575783	[7]	[7,7]	8	hSpCas9	positive selection	3880684
91001087	91001110	14	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CTGAAGGTCCTAGGAACTGGAGG	RPS6KA5	ENSG00000100784	0.28131574695673855	[6]	[6,6]	7	hSpCas9	positive selection	3880685
90923134	90923157	14	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TGGCACCAGATATTGTCAGAGGG	RPS6KA5	ENSG00000100784	0.2099690662584238	[5]	[4,5]	5	hSpCas9	positive selection	3880686
91001079	91001102	14	+	26780180	A375	viability	AAGACTTACCTCCAGTTCCTAGG	RPS6KA5	ENSG00000100784	0.439070007888485	[]	[]	1	hSpCas9	negative selection	3990707
90978304	90978327	14	+	26780180	A375	viability	ACCTAAAATGAGATGAAGTTTGG	RPS6KA5	ENSG00000100784	0.965976684206068	[]	[]	4	hSpCas9	negative selection	3990708
90978465	90978488	14	+	26780180	A375	viability	CATACAGCTTTCCAGTATCATGG	RPS6KA5	ENSG00000100784	1.1025942418034	[]	[]	5	hSpCas9	negative selection	3990709
90947434	90947457	14	-	26780180	A375	viability	TGCCCTCGAACATCTCCACAAGG	RPS6KA5	ENSG00000100784	0.154544328690457	[]	[]	0	hSpCas9	negative selection	3990710
90947431	90947454	14	+	26780180	A375	viability	TTACCTTGTGGAGATGTTCGAGG	RPS6KA5	ENSG00000100784	0.517205126460073	[]	[]	1	hSpCas9	negative selection	3990711
90978397	90978420	14	+	26780180	A375	viability	TTCTGTCCTTGTATGCTCTGTGG	RPS6KA5	ENSG00000100784	0.96373145584526	[]	[]	4	hSpCas9	negative selection	3990712
91001079	91001102	14	+	26780180	HT29	viability (GeCKOv2 library)	AAGACTTACCTCCAGTTCCTAGG	RPS6KA5	ENSG00000100784	-0.312072861471826	[]	[]	-7	hSpCas9	negative selection	4098673
90978304	90978327	14	+	26780180	HT29	viability (GeCKOv2 library)	ACCTAAAATGAGATGAAGTTTGG	RPS6KA5	ENSG00000100784	0.815937489753455	[]	[]	3	hSpCas9	negative selection	4098674
90978465	90978488	14	+	26780180	HT29	viability (GeCKOv2 library)	CATACAGCTTTCCAGTATCATGG	RPS6KA5	ENSG00000100784	0.410155455627753	[]	[]	1	hSpCas9	negative selection	4098675
90947434	90947457	14	-	26780180	HT29	viability (GeCKOv2 library)	TGCCCTCGAACATCTCCACAAGG	RPS6KA5	ENSG00000100784	0.525609846908772	[]	[]	1	hSpCas9	negative selection	4098676
90947431	90947454	14	+	26780180	HT29	viability (GeCKOv2 library)	TTACCTTGTGGAGATGTTCGAGG	RPS6KA5	ENSG00000100784	0.650497773000609	[]	[]	2	hSpCas9	negative selection	4098677
90978397	90978420	14	+	26780180	HT29	viability (GeCKOv2 library)	TTCTGTCCTTGTATGCTCTGTGG	RPS6KA5	ENSG00000100784	0.20528817283044	[]	[]	0	hSpCas9	negative selection	4098678
91001079	91001102	14	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	AAGACTTACCTCCAGTTCCTAGG	RPS6KA5	ENSG00000100784	0.051507228825177664	[5]	[3,3]	1	hSpCas9	positive selection	4167589
90978304	90978327	14	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	ACCTAAAATGAGATGAAGTTTGG	RPS6KA5	ENSG00000100784	0.23529939488328797	[3]	[2,2]	6	hSpCas9	positive selection	4167590
91001103	91001126	14	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	AGAAAATTTTGAGCTCCTGAAGG	RPS6KA5	ENSG00000100784	-0.11276524411867528	[1]	[0,0]	-3	hSpCas9	positive selection	4167591
91001079	91001102	14	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	AAGACTTACCTCCAGTTCCTAGG	RPS6KA5	ENSG00000100784	0.39465669644278567	[5]	[4,5,5,0]	3	hSpCas9	positive selection	4231611
90978304	90978327	14	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	ACCTAAAATGAGATGAAGTTTGG	RPS6KA5	ENSG00000100784	-0.18385731621475404	[3]	[0,4,1,0]	-3	hSpCas9	positive selection	4231612
91001103	91001126	14	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	AGAAAATTTTGAGCTCCTGAAGG	RPS6KA5	ENSG00000100784	0.1843538488185271	[3]	[1,2,1,0]	1	hSpCas9	positive selection	4231613
90947431	90947454	14	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TTACCTTGTGGAGATGTTCGAGG	RPS6KA5	ENSG00000100784	0.15832205197613236	[0]	[1,0]	3	hSpCas9	positive selection	4295801
90947434	90947457	14	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TGCCCTCGAACATCTCCACAAGG	RPS6KA5	ENSG00000100784	0.14725447320260796	[3]	[2,2]	3	hSpCas9	positive selection	4295802
90978465	90978488	14	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CATACAGCTTTCCAGTATCATGG	RPS6KA5	ENSG00000100784	-0.009952452624062913	[2]	[2,1]	0	hSpCas9	positive selection	4295803
90978397	90978420	14	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TTCTGTCCTTGTATGCTCTGTGG	RPS6KA5	ENSG00000100784	0.1561054672746795	[3]	[3,2]	3	hSpCas9	positive selection	4360054
91001079	91001102	14	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AAGACTTACCTCCAGTTCCTAGG	RPS6KA5	ENSG00000100784	0.505834328748314	[4]	[5,4]	9	hSpCas9	positive selection	4360055
90978304	90978327	14	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ACCTAAAATGAGATGAAGTTTGG	RPS6KA5	ENSG00000100784	0.10942428079129257	[2]	[1,1]	2	hSpCas9	positive selection	4360056
90978476	90978498	14	-	27760321	OCIAML3	viability	AAATAAGTGGCCATGATACTGG	RPS6KA5	ENSG00000100784	1.0586499204596258	[173,140]	[170,364]	9	hSpCas9	negative selection	4435963
91001087	91001109	14	-	27760321	OCIAML3	viability	TGAAGGTCCTAGGAACTGGAGG	RPS6KA5	ENSG00000100784	0.6351843326651855	[374,302]	[366,464]	7	hSpCas9	negative selection	4435964
90920202	90920224	14	+	27760321	OCIAML3	viability	TTACCTAGATATCTCAGCTTGG	RPS6KA5	ENSG00000100784	0.005352158585832267	[182,166]	[112,168]	0	hSpCas9	negative selection	4435965
90923132	90923154	14	-	27760321	OCIAML3	viability	CACCAGATATTGTCAGAGGGGG	RPS6KA5	ENSG00000100784	0.9857411396808157	[528,440]	[632,897]	9	hSpCas9	negative selection	4435966
90943122	90943144	14	-	27760321	OCIAML3	viability	CTTGATTCTAATGGCCATGTGG	RPS6KA5	ENSG00000100784	1.1503289126584817	[474,413]	[682,882]	9	hSpCas9	negative selection	4435967
90978476	90978498	14	-	27760321	OCIAML2	viability	AAATAAGTGGCCATGATACTGG	RPS6KA5	ENSG00000100784	0.024309575161176378	[173,140]	[61,216]	0	hSpCas9	negative selection	4519426
91001087	91001109	14	-	27760321	OCIAML2	viability	TGAAGGTCCTAGGAACTGGAGG	RPS6KA5	ENSG00000100784	0.3123187133465891	[374,302]	[323,357]	4	hSpCas9	negative selection	4519427
90920202	90920224	14	+	27760321	OCIAML2	viability	TTACCTAGATATCTCAGCTTGG	RPS6KA5	ENSG00000100784	0.16140968601986083	[182,166]	[162,151]	2	hSpCas9	negative selection	4519428
90923132	90923154	14	-	27760321	OCIAML2	viability	CACCAGATATTGTCAGAGGGGG	RPS6KA5	ENSG00000100784	0.11940617331480718	[528,440]	[382,478]	1	hSpCas9	negative selection	4519429
90943122	90943144	14	-	27760321	OCIAML2	viability	CTTGATTCTAATGGCCATGTGG	RPS6KA5	ENSG00000100784	0.2923339052904919	[474,413]	[371,527]	4	hSpCas9	negative selection	4519430
90978476	90978498	14	-	27760321	MV411	viability	AAATAAGTGGCCATGATACTGG	RPS6KA5	ENSG00000100784	-1.035975835667601	[173,140]	[71,17]	-6	hSpCas9	negative selection	4602889
91001087	91001109	14	-	27760321	MV411	viability	TGAAGGTCCTAGGAACTGGAGG	RPS6KA5	ENSG00000100784	0.07360999581081223	[374,302]	[158,346]	0	hSpCas9	negative selection	4602890
90920202	90920224	14	+	27760321	MV411	viability	TTACCTAGATATCTCAGCTTGG	RPS6KA5	ENSG00000100784	2.040161450715318	[182,166]	[652,206]	9	hSpCas9	negative selection	4602891
90923132	90923154	14	-	27760321	MV411	viability	CACCAGATATTGTCAGAGGGGG	RPS6KA5	ENSG00000100784	0.7340838624508214	[528,440]	[697,277]	5	hSpCas9	negative selection	4602892
90943122	90943144	14	-	27760321	MV411	viability	CTTGATTCTAATGGCCATGTGG	RPS6KA5	ENSG00000100784	0.5844595447584919	[474,413]	[200,795]	4	hSpCas9	negative selection	4602893
90978476	90978498	14	-	27760321	HL60	viability	AAATAAGTGGCCATGATACTGG	RPS6KA5	ENSG00000100784	-0.7501159224431211	[173,140]	[78,72]	-7	hSpCas9	negative selection	4686352
91001087	91001109	14	-	27760321	HL60	viability	TGAAGGTCCTAGGAACTGGAGG	RPS6KA5	ENSG00000100784	-1.0026904090781998	[374,302]	[168,103]	-7	hSpCas9	negative selection	4686353
90920202	90920224	14	+	27760321	HL60	viability	TTACCTAGATATCTCAGCTTGG	RPS6KA5	ENSG00000100784	0.9544052595194905	[182,166]	[272,280]	8	hSpCas9	negative selection	4686354
90923132	90923154	14	-	27760321	HL60	viability	CACCAGATATTGTCAGAGGGGG	RPS6KA5	ENSG00000100784	0.05296104398512763	[528,440]	[335,486]	0	hSpCas9	negative selection	4686355
90943122	90943144	14	-	27760321	HL60	viability	CTTGATTCTAATGGCCATGTGG	RPS6KA5	ENSG00000100784	0.626308088423547	[474,413]	[481,640]	7	hSpCas9	negative selection	4686356
90978476	90978498	14	-	27760321	HT1080	viability	AAATAAGTGGCCATGATACTGG	RPS6KA5	ENSG00000100784	1.4168367923593939	[140,109]	[90,179]	7	hSpCas9	negative selection	4769815
91001087	91001109	14	-	27760321	HT1080	viability	TGAAGGTCCTAGGAACTGGAGG	RPS6KA5	ENSG00000100784	2.3167633630576105	[302,236]	[418,663]	9	hSpCas9	negative selection	4769816
90920202	90920224	14	+	27760321	HT1080	viability	TTACCTAGATATCTCAGCTTGG	RPS6KA5	ENSG00000100784	0.8986207968848876	[166,130]	[40,186]	5	hSpCas9	negative selection	4769817
90923132	90923154	14	-	27760321	HT1080	viability	CACCAGATATTGTCAGAGGGGG	RPS6KA5	ENSG00000100784	0.9216522529590083	[440,343]	[299,291]	5	hSpCas9	negative selection	4769818
90943122	90943144	14	-	27760321	HT1080	viability	CTTGATTCTAATGGCCATGTGG	RPS6KA5	ENSG00000100784	-0.8668496157935001	[413,322]	[111,45]	-4	hSpCas9	negative selection	4769819
90978476	90978498	14	-	27760321	HT29	viability after 7 days	AAATAAGTGGCCATGATACTGG	RPS6KA5	ENSG00000100784	-0.44965995205794895	[140,109]	[47,137,156]	-6	hSpCas9	negative selection	4853278
91001087	91001109	14	-	27760321	HT29	viability after 7 days	TGAAGGTCCTAGGAACTGGAGG	RPS6KA5	ENSG00000100784	0.08908595419932047	[302,236]	[384,303,418]	1	hSpCas9	negative selection	4853279
90920202	90920224	14	+	27760321	HT29	viability after 7 days	TTACCTAGATATCTCAGCTTGG	RPS6KA5	ENSG00000100784	0.412839740341554	[166,130]	[258,265,240]	6	hSpCas9	negative selection	4853280
90923132	90923154	14	-	27760321	HT29	viability after 7 days	CACCAGATATTGTCAGAGGGGG	RPS6KA5	ENSG00000100784	0.0798257662201022	[440,343]	[543,594,463]	1	hSpCas9	negative selection	4853281
90943122	90943144	14	-	27760321	HT29	viability after 7 days	CTTGATTCTAATGGCCATGTGG	RPS6KA5	ENSG00000100784	-0.14249481772264505	[413,322]	[325,538,407]	-2	hSpCas9	negative selection	4853282
90978476	90978498	14	-	27760321	HT29	viability after 25 days	AAATAAGTGGCCATGATACTGG	RPS6KA5	ENSG00000100784	-0.5344612650739671	[140,109]	[77,105,115]	-5	hSpCas9	negative selection	4936741
91001087	91001109	14	-	27760321	HT29	viability after 25 days	TGAAGGTCCTAGGAACTGGAGG	RPS6KA5	ENSG00000100784	0.5191267471605288	[302,236]	[391,436,506]	6	hSpCas9	negative selection	4936742
90920202	90920224	14	+	27760321	HT29	viability after 25 days	TTACCTAGATATCTCAGCTTGG	RPS6KA5	ENSG00000100784	0.4345278103755498	[166,130]	[199,202,295]	5	hSpCas9	negative selection	4936743
90923132	90923154	14	-	27760321	HT29	viability after 25 days	CACCAGATATTGTCAGAGGGGG	RPS6KA5	ENSG00000100784	0.38645092328426495	[440,343]	[667,342,759]	4	hSpCas9	negative selection	4936744
90943122	90943144	14	-	27760321	HT29	viability after 25 days	CTTGATTCTAATGGCCATGTGG	RPS6KA5	ENSG00000100784	0.5496410855195896	[413,322]	[498,590,782]	6	hSpCas9	negative selection	4936745
90978476	90978498	14	-	27760321	HT29	viability after 22 days	AAATAAGTGGCCATGATACTGG	RPS6KA5	ENSG00000100784	-0.06764145909065644	[140,109]	[100,104,210]	0	hSpCas9	negative selection	5020204
91001087	91001109	14	-	27760321	HT29	viability after 22 days	TGAAGGTCCTAGGAACTGGAGG	RPS6KA5	ENSG00000100784	0.41901387089074515	[302,236]	[344,291,618]	4	hSpCas9	negative selection	5020205
90920202	90920224	14	+	27760321	HT29	viability after 22 days	TTACCTAGATATCTCAGCTTGG	RPS6KA5	ENSG00000100784	0.056003730962662424	[166,130]	[173,132,230]	0	hSpCas9	negative selection	5020206
90923132	90923154	14	-	27760321	HT29	viability after 22 days	CACCAGATATTGTCAGAGGGGG	RPS6KA5	ENSG00000100784	0.7936745779953824	[440,343]	[765,613,981]	8	hSpCas9	negative selection	5020207
90943122	90943144	14	-	27760321	HT29	viability after 22 days	CTTGATTCTAATGGCCATGTGG	RPS6KA5	ENSG00000100784	0.13121208492820235	[413,322]	[412,426,561]	1	hSpCas9	negative selection	5020208
90978476	90978498	14	-	27760321	HT29	viability after 19 days	AAATAAGTGGCCATGATACTGG	RPS6KA5	ENSG00000100784	0.37295293402033325	[140,109]	[217,321,26]	3	hSpCas9	negative selection	5103667
91001087	91001109	14	-	27760321	HT29	viability after 19 days	TGAAGGTCCTAGGAACTGGAGG	RPS6KA5	ENSG00000100784	-0.14721259228215583	[302,236]	[458,189,208]	-1	hSpCas9	negative selection	5103668
90920202	90920224	14	+	27760321	HT29	viability after 19 days	TTACCTAGATATCTCAGCTTGG	RPS6KA5	ENSG00000100784	0.49130298825610774	[166,130]	[380,179,174]	5	hSpCas9	negative selection	5103669
90923132	90923154	14	-	27760321	HT29	viability after 19 days	CACCAGATATTGTCAGAGGGGG	RPS6KA5	ENSG00000100784	0.23060668261505607	[440,343]	[498,395,675]	2	hSpCas9	negative selection	5103670
90943122	90943144	14	-	27760321	HT29	viability after 19 days	CTTGATTCTAATGGCCATGTGG	RPS6KA5	ENSG00000100784	0.2957190765124945	[413,322]	[603,528,430]	3	hSpCas9	negative selection	5103671
90978476	90978498	14	-	27760321	HT29	viability after 16 days	AAATAAGTGGCCATGATACTGG	RPS6KA5	ENSG00000100784	-0.564123235515936	[140,109]	[93,86,103]	-5	hSpCas9	negative selection	5187130
91001087	91001109	14	-	27760321	HT29	viability after 16 days	TGAAGGTCCTAGGAACTGGAGG	RPS6KA5	ENSG00000100784	0.3183393138542109	[302,236]	[690,175,297]	3	hSpCas9	negative selection	5187131
90920202	90920224	14	+	27760321	HT29	viability after 16 days	TTACCTAGATATCTCAGCTTGG	RPS6KA5	ENSG00000100784	-0.5646168405896677	[166,130]	[120,112,104]	-5	hSpCas9	negative selection	5187132
90923132	90923154	14	-	27760321	HT29	viability after 16 days	CACCAGATATTGTCAGAGGGGG	RPS6KA5	ENSG00000100784	0.3195981553842021	[440,343]	[755,493,414]	3	hSpCas9	negative selection	5187133
90943122	90943144	14	-	27760321	HT29	viability after 16 days	CTTGATTCTAATGGCCATGTGG	RPS6KA5	ENSG00000100784	0.27812493965312085	[413,322]	[405,454,630]	3	hSpCas9	negative selection	5187134
90978476	90978498	14	-	27760321	HT29	viability after 13 days	AAATAAGTGGCCATGATACTGG	RPS6KA5	ENSG00000100784	-0.5987209829868645	[140,109]	[80,137,70]	-6	hSpCas9	negative selection	5270593
91001087	91001109	14	-	27760321	HT29	viability after 13 days	TGAAGGTCCTAGGAACTGGAGG	RPS6KA5	ENSG00000100784	1.0669233320589115	[302,236]	[1041,578,364]	9	hSpCas9	negative selection	5270594
90920202	90920224	14	+	27760321	HT29	viability after 13 days	TTACCTAGATATCTCAGCTTGG	RPS6KA5	ENSG00000100784	-0.11699641144037232	[166,130]	[138,139,196]	-1	hSpCas9	negative selection	5270595
90923132	90923154	14	-	27760321	HT29	viability after 13 days	CACCAGATATTGTCAGAGGGGG	RPS6KA5	ENSG00000100784	0.1531564648580332	[440,343]	[432,595,490]	1	hSpCas9	negative selection	5270596
90943122	90943144	14	-	27760321	HT29	viability after 13 days	CTTGATTCTAATGGCCATGTGG	RPS6KA5	ENSG00000100784	0.07657011044494888	[413,322]	[374,637,345]	0	hSpCas9	negative selection	5270597
90978476	90978498	14	-	27760321	HT29	viability after 10 days	AAATAAGTGGCCATGATACTGG	RPS6KA5	ENSG00000100784	-0.1645248222264688	[140,109]	[173,196,51]	-2	hSpCas9	negative selection	5354056
91001087	91001109	14	-	27760321	HT29	viability after 10 days	TGAAGGTCCTAGGAACTGGAGG	RPS6KA5	ENSG00000100784	0.5145985224774068	[302,236]	[565,465,413]	7	hSpCas9	negative selection	5354057
90920202	90920224	14	+	27760321	HT29	viability after 10 days	TTACCTAGATATCTCAGCTTGG	RPS6KA5	ENSG00000100784	0.17136974022522433	[166,130]	[377,120,128]	2	hSpCas9	negative selection	5354058
90923132	90923154	14	-	27760321	HT29	viability after 10 days	CACCAGATATTGTCAGAGGGGG	RPS6KA5	ENSG00000100784	0.7471119011146607	[440,343]	[1012,749,704]	8	hSpCas9	negative selection	5354059
90943122	90943144	14	-	27760321	HT29	viability after 10 days	CTTGATTCTAATGGCCATGTGG	RPS6KA5	ENSG00000100784	0.252389596021472	[413,322]	[602,602,441]	3	hSpCas9	negative selection	5354060
90978476	90978498	14	-	27760321	MOLM13	viability	AAATAAGTGGCCATGATACTGG	RPS6KA5	ENSG00000100784	1.477378613138887	[173,140]	[479,46]	8	hSpCas9	negative selection	5437519
91001087	91001109	14	-	27760321	MOLM13	viability	TGAAGGTCCTAGGAACTGGAGG	RPS6KA5	ENSG00000100784	0.74339405260282	[374,302]	[540,128]	5	hSpCas9	negative selection	5437520
90920202	90920224	14	+	27760321	MOLM13	viability	TTACCTAGATATCTCAGCTTGG	RPS6KA5	ENSG00000100784	3.0068376568139117	[182,166]	[345,1173]	9	hSpCas9	negative selection	5437521
90923132	90923154	14	-	27760321	MOLM13	viability	CACCAGATATTGTCAGAGGGGG	RPS6KA5	ENSG00000100784	0.915746053812457	[528,440]	[465,554]	6	hSpCas9	negative selection	5437522
90943122	90943144	14	-	27760321	MOLM13	viability	CTTGATTCTAATGGCCATGTGG	RPS6KA5	ENSG00000100784	0.8278886919852291	[474,413]	[650,267]	6	hSpCas9	negative selection	5437523
91060100	91060123	14	+	27661255	K562	viability	GGTGCCCGCCGCTCATTCCCGGG	RPS6KA5	ENSG00000100784	0.023177760889833476	[1542,1469]	[1386,1084]	0	dCas9-KRAB	negative selection	5508635
90947431	90947454	14	+	27260156	BXPC3	viability	TTACCTTGTGGAGATGTTCGAGG	RPS6KA5	ENSG00000100784	0.021425776642768568	[38]	[7,43,37,83]	0	hSpCas9	negative selection	5568261
90947434	90947457	14	-	27260156	BXPC3	viability	TGCCCTCGAACATCTCCACAAGG	RPS6KA5	ENSG00000100784	0.30317618853638173	[470]	[464,665,610,708]	6	hSpCas9	negative selection	5568262
90978465	90978488	14	+	27260156	BXPC3	viability	CATACAGCTTTCCAGTATCATGG	RPS6KA5	ENSG00000100784	-0.09139699378450417	[311]	[236,251,356,399]	-2	hSpCas9	negative selection	5568263
90978397	90978420	14	+	27260156	BXPC3	viability	TTCTGTCCTTGTATGCTCTGTGG	RPS6KA5	ENSG00000100784	-0.04400699447969103	[927]	[784,794,1215,999]	-1	hSpCas9	negative selection	5632514
91001079	91001102	14	+	27260156	BXPC3	viability	AAGACTTACCTCCAGTTCCTAGG	RPS6KA5	ENSG00000100784	0.20379630100500634	[1409]	[1539,1381,1932,2002]	4	hSpCas9	negative selection	5632515
90978304	90978327	14	+	27260156	BXPC3	viability	ACCTAAAATGAGATGAAGTTTGG	RPS6KA5	ENSG00000100784	0.041109856429788705	[204]	[180,217,215,276]	0	hSpCas9	negative selection	5632516
90947431	90947454	14	+	27260156	A673	viability	TTACCTTGTGGAGATGTTCGAGG	RPS6KA5	ENSG00000100784	-0.6041794467145509	[38]	[25,49,18,26]	-9	hSpCas9	negative selection	5689512
90947434	90947457	14	-	27260156	A673	viability	TGCCCTCGAACATCTCCACAAGG	RPS6KA5	ENSG00000100784	0.37361351344846816	[470]	[798,650,638,857]	8	hSpCas9	negative selection	5689513
90978465	90978488	14	+	27260156	A673	viability	CATACAGCTTTCCAGTATCATGG	RPS6KA5	ENSG00000100784	0.24793983943971348	[311]	[442,411,375,554]	6	hSpCas9	negative selection	5689514
90978397	90978420	14	+	27260156	A673	viability	TTCTGTCCTTGTATGCTCTGTGG	RPS6KA5	ENSG00000100784	0.05525142091828761	[927]	[990,1127,1298,1192]	1	hSpCas9	negative selection	5753765
91001079	91001102	14	+	27260156	A673	viability	AAGACTTACCTCCAGTTCCTAGG	RPS6KA5	ENSG00000100784	0.20298401701784297	[1409]	[2063,1712,1872,2173]	5	hSpCas9	negative selection	5753766
90978304	90978327	14	+	27260156	A673	viability	ACCTAAAATGAGATGAAGTTTGG	RPS6KA5	ENSG00000100784	-0.5992798987717021	[204]	[195,143,122,192]	-9	hSpCas9	negative selection	5753767
90947431	90947454	14	+	27260156	A375	viability	TTACCTTGTGGAGATGTTCGAGG	RPS6KA5	ENSG00000100784	0.8892788159942944	[38]	[46,129,51,110]	9	hSpCas9	negative selection	5810763
90947434	90947457	14	-	27260156	A375	viability	TGCCCTCGAACATCTCCACAAGG	RPS6KA5	ENSG00000100784	0.650995703488273	[470]	[888,1019,683,878]	8	hSpCas9	negative selection	5810764
90978465	90978488	14	+	27260156	A375	viability	CATACAGCTTTCCAGTATCATGG	RPS6KA5	ENSG00000100784	0.6304063496460972	[311]	[737,498,551,468]	8	hSpCas9	negative selection	5810765
90978397	90978420	14	+	27260156	A375	viability	TTCTGTCCTTGTATGCTCTGTGG	RPS6KA5	ENSG00000100784	0.13553651418914792	[927]	[1233,1285,1101,1153]	2	hSpCas9	negative selection	5875016
91001079	91001102	14	+	27260156	A375	viability	AAGACTTACCTCCAGTTCCTAGG	RPS6KA5	ENSG00000100784	0.5820816112878813	[1409]	[3062,2811,1929,2138]	8	hSpCas9	negative selection	5875017
90978304	90978327	14	+	27260156	A375	viability	ACCTAAAATGAGATGAAGTTTGG	RPS6KA5	ENSG00000100784	0.243806095751665	[204]	[284,223,223,379]	3	hSpCas9	negative selection	5875018
90947431	90947454	14	+	27260156	COLO741	viability	TTACCTTGTGGAGATGTTCGAGG	RPS6KA5	ENSG00000100784	-0.5388947715303676	[38]	[23,71,7]	-8	hSpCas9	negative selection	5932014
90947434	90947457	14	-	27260156	COLO741	viability	TGCCCTCGAACATCTCCACAAGG	RPS6KA5	ENSG00000100784	0.5682710572002326	[470]	[959,959,769]	9	hSpCas9	negative selection	5932015
90978465	90978488	14	+	27260156	COLO741	viability	CATACAGCTTTCCAGTATCATGG	RPS6KA5	ENSG00000100784	0.35239588744903727	[311]	[510,507,506]	7	hSpCas9	negative selection	5932016
90978397	90978420	14	+	27260156	COLO741	viability	TTCTGTCCTTGTATGCTCTGTGG	RPS6KA5	ENSG00000100784	0.2604740733305334	[927]	[1566,1394,1315]	5	hSpCas9	negative selection	5996267
91001079	91001102	14	+	27260156	COLO741	viability	AAGACTTACCTCCAGTTCCTAGG	RPS6KA5	ENSG00000100784	0.21153534761943082	[1409]	[2481,2020,1804]	4	hSpCas9	negative selection	5996268
90978304	90978327	14	+	27260156	COLO741	viability	ACCTAAAATGAGATGAAGTTTGG	RPS6KA5	ENSG00000100784	-0.4479563936558397	[204]	[202,215,159]	-7	hSpCas9	negative selection	5996269
90947431	90947454	14	+	27260156	CAL120	viability	TTACCTTGTGGAGATGTTCGAGG	RPS6KA5	ENSG00000100784	-0.624856555699961	[38]	[71,24,3]	-7	hSpCas9	negative selection	6053265
90947434	90947457	14	-	27260156	CAL120	viability	TGCCCTCGAACATCTCCACAAGG	RPS6KA5	ENSG00000100784	0.38065264844842445	[470]	[789,742,759]	6	hSpCas9	negative selection	6053266
90978465	90978488	14	+	27260156	CAL120	viability	CATACAGCTTTCCAGTATCATGG	RPS6KA5	ENSG00000100784	0.4098589517257546	[311]	[869,409,323]	6	hSpCas9	negative selection	6053267
90978397	90978420	14	+	27260156	CAL120	viability	TTCTGTCCTTGTATGCTCTGTGG	RPS6KA5	ENSG00000100784	0.0841522112027201	[927]	[1018,945,1667]	1	hSpCas9	negative selection	6117518
91001079	91001102	14	+	27260156	CAL120	viability	AAGACTTACCTCCAGTTCCTAGG	RPS6KA5	ENSG00000100784	0.28596924634777476	[1409]	[2796,1981,1743]	4	hSpCas9	negative selection	6117519
90978304	90978327	14	+	27260156	CAL120	viability	ACCTAAAATGAGATGAAGTTTGG	RPS6KA5	ENSG00000100784	0.2549580636184573	[204]	[427,271,232]	4	hSpCas9	negative selection	6117520
90947431	90947454	14	+	27260156	CADOES1	viability	TTACCTTGTGGAGATGTTCGAGG	RPS6KA5	ENSG00000100784	1.1001511164263897	[38]	[39,59,109,101]	9	hSpCas9	negative selection	6174516
90947434	90947457	14	-	27260156	CADOES1	viability	TGCCCTCGAACATCTCCACAAGG	RPS6KA5	ENSG00000100784	0.5519868134211794	[470]	[760,664,518,622]	8	hSpCas9	negative selection	6174517
90978465	90978488	14	+	27260156	CADOES1	viability	CATACAGCTTTCCAGTATCATGG	RPS6KA5	ENSG00000100784	0.2552355860663465	[311]	[391,346,356,286]	4	hSpCas9	negative selection	6174518
90978397	90978420	14	+	27260156	CADOES1	viability	TTCTGTCCTTGTATGCTCTGTGG	RPS6KA5	ENSG00000100784	0.106506008125132	[927]	[972,844,958,939]	1	hSpCas9	negative selection	6238769
91001079	91001102	14	+	27260156	CADOES1	viability	AAGACTTACCTCCAGTTCCTAGG	RPS6KA5	ENSG00000100784	0.27479061518481873	[1409]	[1626,1659,1528,1527]	4	hSpCas9	negative selection	6238770
90978304	90978327	14	+	27260156	CADOES1	viability	ACCTAAAATGAGATGAAGTTTGG	RPS6KA5	ENSG00000100784	0.041350632232060924	[204]	[196,120,235,231]	0	hSpCas9	negative selection	6238771
90947431	90947454	14	+	27260156	EWS502	viability	TTACCTTGTGGAGATGTTCGAGG	RPS6KA5	ENSG00000100784	-0.30980058010267	[38]	[50,19,50,7]	-5	hSpCas9	negative selection	6295767
90947434	90947457	14	-	27260156	EWS502	viability	TGCCCTCGAACATCTCCACAAGG	RPS6KA5	ENSG00000100784	0.22493713481100341	[470]	[632,500,651,538]	4	hSpCas9	negative selection	6295768
90978465	90978488	14	+	27260156	EWS502	viability	CATACAGCTTTCCAGTATCATGG	RPS6KA5	ENSG00000100784	0.3234144959087227	[311]	[514,350,264,516]	5	hSpCas9	negative selection	6295769
90978397	90978420	14	+	27260156	EWS502	viability	TTCTGTCCTTGTATGCTCTGTGG	RPS6KA5	ENSG00000100784	0.03934288136737962	[927]	[808,1090,1140,1018]	0	hSpCas9	negative selection	6360020
91001079	91001102	14	+	27260156	EWS502	viability	AAGACTTACCTCCAGTTCCTAGG	RPS6KA5	ENSG00000100784	0.4389637306949674	[1409]	[1744,2125,2049,2212]	7	hSpCas9	negative selection	6360021
90978304	90978327	14	+	27260156	EWS502	viability	ACCTAAAATGAGATGAAGTTTGG	RPS6KA5	ENSG00000100784	-0.1326349572430494	[204]	[248,147,163,227]	-2	hSpCas9	negative selection	6360022
90947431	90947454	14	+	27260156	EW8	viability	TTACCTTGTGGAGATGTTCGAGG	RPS6KA5	ENSG00000100784	-0.6272174078749462	[38]	[7,3,27,38]	-8	hSpCas9	negative selection	6417018
90947434	90947457	14	-	27260156	EW8	viability	TGCCCTCGAACATCTCCACAAGG	RPS6KA5	ENSG00000100784	0.26108034291009646	[470]	[557,332,305,666]	5	hSpCas9	negative selection	6417019
90978465	90978488	14	+	27260156	EW8	viability	CATACAGCTTTCCAGTATCATGG	RPS6KA5	ENSG00000100784	0.5604238514922641	[311]	[490,449,308,264]	8	hSpCas9	negative selection	6417020
90978397	90978420	14	+	27260156	EW8	viability	TTCTGTCCTTGTATGCTCTGTGG	RPS6KA5	ENSG00000100784	0.15003213332957455	[927]	[1096,847,541,926]	2	hSpCas9	negative selection	6481271
91001079	91001102	14	+	27260156	EW8	viability	AAGACTTACCTCCAGTTCCTAGG	RPS6KA5	ENSG00000100784	0.22750063013307176	[1409]	[1423,1414,1048,1517]	4	hSpCas9	negative selection	6481272
90978304	90978327	14	+	27260156	EW8	viability	ACCTAAAATGAGATGAAGTTTGG	RPS6KA5	ENSG00000100784	-0.12462606976048551	[204]	[195,97,161,155]	-2	hSpCas9	negative selection	6481273
90947431	90947454	14	+	27260156	CORL105	viability	TTACCTTGTGGAGATGTTCGAGG	RPS6KA5	ENSG00000100784	0.12381819839766095	[38]	[43,38,43,70]	2	hSpCas9	negative selection	6538269
90947434	90947457	14	-	27260156	CORL105	viability	TGCCCTCGAACATCTCCACAAGG	RPS6KA5	ENSG00000100784	0.42434636723048713	[470]	[828,581,1024,574]	7	hSpCas9	negative selection	6538270
90978465	90978488	14	+	27260156	CORL105	viability	CATACAGCTTTCCAGTATCATGG	RPS6KA5	ENSG00000100784	0.14743796310774343	[311]	[539,235,473,386]	2	hSpCas9	negative selection	6538271
90978397	90978420	14	+	27260156	CORL105	viability	TTCTGTCCTTGTATGCTCTGTGG	RPS6KA5	ENSG00000100784	-0.14765382179093922	[927]	[752,871,1221,1106]	-3	hSpCas9	negative selection	6602522
91001079	91001102	14	+	27260156	CORL105	viability	AAGACTTACCTCCAGTTCCTAGG	RPS6KA5	ENSG00000100784	0.14030074973904227	[1409]	[1626,1743,2030,1901]	2	hSpCas9	negative selection	6602523
90978304	90978327	14	+	27260156	CORL105	viability	ACCTAAAATGAGATGAAGTTTGG	RPS6KA5	ENSG00000100784	-0.21113147185745662	[204]	[162,258,227,179]	-4	hSpCas9	negative selection	6602524
90947431	90947454	14	+	27260156	HS294T	viability	TTACCTTGTGGAGATGTTCGAGG	RPS6KA5	ENSG00000100784	0.47258963712214097	[38]	[4,40,24,11]	6	hSpCas9	negative selection	6659520
90947434	90947457	14	-	27260156	HS294T	viability	TGCCCTCGAACATCTCCACAAGG	RPS6KA5	ENSG00000100784	0.5446833893091195	[470]	[172,278,278,353]	7	hSpCas9	negative selection	6659521
90978465	90978488	14	+	27260156	HS294T	viability	CATACAGCTTTCCAGTATCATGG	RPS6KA5	ENSG00000100784	0.7274237944355963	[311]	[247,129,207,211]	8	hSpCas9	negative selection	6659522
90978397	90978420	14	+	27260156	HS294T	viability	TTCTGTCCTTGTATGCTCTGTGG	RPS6KA5	ENSG00000100784	0.3607622427046001	[927]	[378,372,496,631]	5	hSpCas9	negative selection	6723773
91001079	91001102	14	+	27260156	HS294T	viability	AAGACTTACCTCCAGTTCCTAGG	RPS6KA5	ENSG00000100784	0.5642225114772681	[1409]	[555,734,953,1042]	7	hSpCas9	negative selection	6723774
90978304	90978327	14	+	27260156	HS294T	viability	ACCTAAAATGAGATGAAGTTTGG	RPS6KA5	ENSG00000100784	-0.868164726448162	[204]	[39,37,47,48]	-8	hSpCas9	negative selection	6723775
90947431	90947454	14	+	27260156	HCC44	viability	TTACCTTGTGGAGATGTTCGAGG	RPS6KA5	ENSG00000100784	-0.25718889355338526	[38]	[28,7,114,12]	-4	hSpCas9	negative selection	6780771
90947434	90947457	14	-	27260156	HCC44	viability	TGCCCTCGAACATCTCCACAAGG	RPS6KA5	ENSG00000100784	0.14651595616717722	[470]	[824,419,718,461]	2	hSpCas9	negative selection	6780772
90978465	90978488	14	+	27260156	HCC44	viability	CATACAGCTTTCCAGTATCATGG	RPS6KA5	ENSG00000100784	0.3525541150837356	[311]	[522,385,549,374]	6	hSpCas9	negative selection	6780773
90978397	90978420	14	+	27260156	HCC44	viability	TTCTGTCCTTGTATGCTCTGTGG	RPS6KA5	ENSG00000100784	-0.1325693187944672	[927]	[906,939,1048,939]	-2	hSpCas9	negative selection	6845024
91001079	91001102	14	+	27260156	HCC44	viability	AAGACTTACCTCCAGTTCCTAGG	RPS6KA5	ENSG00000100784	0.37788591485421974	[1409]	[2341,1742,2399,1919]	6	hSpCas9	negative selection	6845025
90978304	90978327	14	+	27260156	HCC44	viability	ACCTAAAATGAGATGAAGTTTGG	RPS6KA5	ENSG00000100784	0.40904456888805596	[204]	[131,459,389,225]	6	hSpCas9	negative selection	6845026
90947431	90947454	14	+	27260156	G402	viability	TTACCTTGTGGAGATGTTCGAGG	RPS6KA5	ENSG00000100784	0.595385070715138	[38]	[38,190,61,0]	7	hSpCas9	negative selection	6902022
90947434	90947457	14	-	27260156	G402	viability	TGCCCTCGAACATCTCCACAAGG	RPS6KA5	ENSG00000100784	0.7955598515780605	[470]	[760,746,1587,848]	8	hSpCas9	negative selection	6902023
90978465	90978488	14	+	27260156	G402	viability	CATACAGCTTTCCAGTATCATGG	RPS6KA5	ENSG00000100784	0.6702065387719902	[311]	[1032,779,291,397]	8	hSpCas9	negative selection	6902024
90978397	90978420	14	+	27260156	G402	viability	TTCTGTCCTTGTATGCTCTGTGG	RPS6KA5	ENSG00000100784	0.46439622269603154	[927]	[2216,1983,845,1326]	6	hSpCas9	negative selection	6966275
91001079	91001102	14	+	27260156	G402	viability	AAGACTTACCTCCAGTTCCTAGG	RPS6KA5	ENSG00000100784	0.2033920906202955	[1409]	[1598,1981,2784,1517]	2	hSpCas9	negative selection	6966276
90978304	90978327	14	+	27260156	G402	viability	ACCTAAAATGAGATGAAGTTTGG	RPS6KA5	ENSG00000100784	0.1793343726956118	[204]	[133,345,32,585]	2	hSpCas9	negative selection	6966277
90947431	90947454	14	+	27260156	L33	viability	TTACCTTGTGGAGATGTTCGAGG	RPS6KA5	ENSG00000100784	-0.27324928733787424	[38]	[18,8,32,35]	-6	hSpCas9	negative selection	7023273
90947434	90947457	14	-	27260156	L33	viability	TGCCCTCGAACATCTCCACAAGG	RPS6KA5	ENSG00000100784	0.59629785340993	[470]	[643,264,507,750]	9	hSpCas9	negative selection	7023274
90978465	90978488	14	+	27260156	L33	viability	CATACAGCTTTCCAGTATCATGG	RPS6KA5	ENSG00000100784	0.7513005880492135	[311]	[565,207,340,483]	9	hSpCas9	negative selection	7023275
90978397	90978420	14	+	27260156	L33	viability	TTCTGTCCTTGTATGCTCTGTGG	RPS6KA5	ENSG00000100784	-0.2650790677616671	[927]	[659,339,450,882]	-6	hSpCas9	negative selection	7087526
91001079	91001102	14	+	27260156	L33	viability	AAGACTTACCTCCAGTTCCTAGG	RPS6KA5	ENSG00000100784	0.3441034670095815	[1409]	[1981,746,1079,1631]	7	hSpCas9	negative selection	7087527
90978304	90978327	14	+	27260156	L33	viability	ACCTAAAATGAGATGAAGTTTGG	RPS6KA5	ENSG00000100784	-0.06211482883577024	[204]	[194,88,118,183]	-1	hSpCas9	negative selection	7087528
90947431	90947454	14	+	27260156	K562	viability	TTACCTTGTGGAGATGTTCGAGG	RPS6KA5	ENSG00000100784	0.13033405299236644	[38]	[65,17,5,59]	1	hSpCas9	negative selection	7144524
90947434	90947457	14	-	27260156	K562	viability	TGCCCTCGAACATCTCCACAAGG	RPS6KA5	ENSG00000100784	-0.01233215235266101	[470]	[360,280,667,342]	0	hSpCas9	negative selection	7144525
90978465	90978488	14	+	27260156	K562	viability	CATACAGCTTTCCAGTATCATGG	RPS6KA5	ENSG00000100784	0.5150161581446391	[311]	[693,312,348,260]	6	hSpCas9	negative selection	7144526
90978397	90978420	14	+	27260156	K562	viability	TTCTGTCCTTGTATGCTCTGTGG	RPS6KA5	ENSG00000100784	0.4158044031109315	[927]	[1145,951,1396,912]	5	hSpCas9	negative selection	7208777
91001079	91001102	14	+	27260156	K562	viability	AAGACTTACCTCCAGTTCCTAGG	RPS6KA5	ENSG00000100784	0.5321847503474473	[1409]	[1693,1291,2137,2041]	6	hSpCas9	negative selection	7208778
90978304	90978327	14	+	27260156	K562	viability	ACCTAAAATGAGATGAAGTTTGG	RPS6KA5	ENSG00000100784	0.1256588754228578	[204]	[132,76,199,352]	1	hSpCas9	negative selection	7208779
90947431	90947454	14	+	27260156	HT29	viability	TTACCTTGTGGAGATGTTCGAGG	RPS6KA5	ENSG00000100784	-0.41275856449851744	[38]	[14,44,68,14]	-6	hSpCas9	negative selection	7265775
90947434	90947457	14	-	27260156	HT29	viability	TGCCCTCGAACATCTCCACAAGG	RPS6KA5	ENSG00000100784	0.4637301591184261	[470]	[877,776,826,688]	8	hSpCas9	negative selection	7265776
90978465	90978488	14	+	27260156	HT29	viability	CATACAGCTTTCCAGTATCATGG	RPS6KA5	ENSG00000100784	0.40524736983785486	[311]	[475,394,636,487]	7	hSpCas9	negative selection	7265777
90978397	90978420	14	+	27260156	HT29	viability	TTCTGTCCTTGTATGCTCTGTGG	RPS6KA5	ENSG00000100784	0.046270795521778596	[927]	[1043,1151,1274,1168]	0	hSpCas9	negative selection	7330028
91001079	91001102	14	+	27260156	HT29	viability	AAGACTTACCTCCAGTTCCTAGG	RPS6KA5	ENSG00000100784	0.33263682429797803	[1409]	[2274,2267,2136,1978]	6	hSpCas9	negative selection	7330029
90978304	90978327	14	+	27260156	HT29	viability	ACCTAAAATGAGATGAAGTTTGG	RPS6KA5	ENSG00000100784	-0.059403978093721665	[204]	[230,276,250,202]	-1	hSpCas9	negative selection	7330030
90947431	90947454	14	+	27260156	MHHES1	viability	TTACCTTGTGGAGATGTTCGAGG	RPS6KA5	ENSG00000100784	0.15493688645171622	[38]	[9,58,47,68]	3	hSpCas9	negative selection	7387026
90947434	90947457	14	-	27260156	MHHES1	viability	TGCCCTCGAACATCTCCACAAGG	RPS6KA5	ENSG00000100784	0.48851930240517705	[470]	[905,744,743,614]	8	hSpCas9	negative selection	7387027
90978465	90978488	14	+	27260156	MHHES1	viability	CATACAGCTTTCCAGTATCATGG	RPS6KA5	ENSG00000100784	0.5222605501227363	[311]	[508,618,429,468]	8	hSpCas9	negative selection	7387028
90978397	90978420	14	+	27260156	MHHES1	viability	TTCTGTCCTTGTATGCTCTGTGG	RPS6KA5	ENSG00000100784	0.1295351102705854	[927]	[1087,1316,1282,922]	2	hSpCas9	negative selection	7451279
91001079	91001102	14	+	27260156	MHHES1	viability	AAGACTTACCTCCAGTTCCTAGG	RPS6KA5	ENSG00000100784	0.30439796805945774	[1409]	[2284,1811,2151,1648]	5	hSpCas9	negative selection	7451280
90978304	90978327	14	+	27260156	MHHES1	viability	ACCTAAAATGAGATGAAGTTTGG	RPS6KA5	ENSG00000100784	0.14504460696927235	[204]	[477,217,200,162]	2	hSpCas9	negative selection	7451281
90947431	90947454	14	+	27260156	MEWO	viability	TTACCTTGTGGAGATGTTCGAGG	RPS6KA5	ENSG00000100784	0.06017260690228632	[38]	[47,46,20]	1	hSpCas9	negative selection	7508277
90947434	90947457	14	-	27260156	MEWO	viability	TGCCCTCGAACATCTCCACAAGG	RPS6KA5	ENSG00000100784	0.5502918112042425	[470]	[748,601,604]	9	hSpCas9	negative selection	7508278
90978465	90978488	14	+	27260156	MEWO	viability	CATACAGCTTTCCAGTATCATGG	RPS6KA5	ENSG00000100784	0.48704172634583703	[311]	[522,266,459]	8	hSpCas9	negative selection	7508279
90978397	90978420	14	+	27260156	MEWO	viability	TTCTGTCCTTGTATGCTCTGTGG	RPS6KA5	ENSG00000100784	0.012928458058655945	[927]	[877,719,1030]	0	hSpCas9	negative selection	7572530
91001079	91001102	14	+	27260156	MEWO	viability	AAGACTTACCTCCAGTTCCTAGG	RPS6KA5	ENSG00000100784	0.21516834113472383	[1409]	[1604,1504,1497]	5	hSpCas9	negative selection	7572531
90978304	90978327	14	+	27260156	MEWO	viability	ACCTAAAATGAGATGAAGTTTGG	RPS6KA5	ENSG00000100784	-0.003492707069422396	[204]	[216,172,188]	0	hSpCas9	negative selection	7572532
90947431	90947454	14	+	27260156	LNCAPCLONEFGC	viability	TTACCTTGTGGAGATGTTCGAGG	RPS6KA5	ENSG00000100784	0.03051624665142416	[38]	[34,32,18,54]	0	hSpCas9	negative selection	7629528
90947434	90947457	14	-	27260156	LNCAPCLONEFGC	viability	TGCCCTCGAACATCTCCACAAGG	RPS6KA5	ENSG00000100784	0.5214406883877636	[470]	[632,648,750,433]	7	hSpCas9	negative selection	7629529
90978465	90978488	14	+	27260156	LNCAPCLONEFGC	viability	CATACAGCTTTCCAGTATCATGG	RPS6KA5	ENSG00000100784	0.18948999141745565	[311]	[260,281,309,437]	3	hSpCas9	negative selection	7629530
90978397	90978420	14	+	27260156	LNCAPCLONEFGC	viability	TTCTGTCCTTGTATGCTCTGTGG	RPS6KA5	ENSG00000100784	0.1535083896548769	[927]	[965,744,1073,986]	2	hSpCas9	negative selection	7693781
91001079	91001102	14	+	27260156	LNCAPCLONEFGC	viability	AAGACTTACCTCCAGTTCCTAGG	RPS6KA5	ENSG00000100784	0.3207763805065629	[1409]	[1480,1479,1871,1597]	5	hSpCas9	negative selection	7693782
90978304	90978327	14	+	27260156	LNCAPCLONEFGC	viability	ACCTAAAATGAGATGAAGTTTGG	RPS6KA5	ENSG00000100784	0.15008086712734925	[204]	[192,202,262,173]	2	hSpCas9	negative selection	7693783
90947431	90947454	14	+	27260156	PANC0327	viability	TTACCTTGTGGAGATGTTCGAGG	RPS6KA5	ENSG00000100784	0.02442850850143463	[38]	[7,86,18,17]	0	hSpCas9	negative selection	7750779
90947434	90947457	14	-	27260156	PANC0327	viability	TGCCCTCGAACATCTCCACAAGG	RPS6KA5	ENSG00000100784	0.3328752143134142	[470]	[529,573,545,451]	5	hSpCas9	negative selection	7750780
90978465	90978488	14	+	27260156	PANC0327	viability	CATACAGCTTTCCAGTATCATGG	RPS6KA5	ENSG00000100784	0.405416383508158	[311]	[491,116,525,375]	6	hSpCas9	negative selection	7750781
90978397	90978420	14	+	27260156	PANC0327	viability	TTCTGTCCTTGTATGCTCTGTGG	RPS6KA5	ENSG00000100784	0.0015700631234485396	[927]	[902,829,1013,559]	0	hSpCas9	negative selection	7815032
91001079	91001102	14	+	27260156	PANC0327	viability	AAGACTTACCTCCAGTTCCTAGG	RPS6KA5	ENSG00000100784	0.10949597434295533	[1409]	[1556,1471,1266,1109]	1	hSpCas9	negative selection	7815033
90978304	90978327	14	+	27260156	PANC0327	viability	ACCTAAAATGAGATGAAGTTTGG	RPS6KA5	ENSG00000100784	0.30453251285012517	[204]	[293,278,97,226]	4	hSpCas9	negative selection	7815034
90947431	90947454	14	+	27260156	NCIH2009	viability	TTACCTTGTGGAGATGTTCGAGG	RPS6KA5	ENSG00000100784	-0.2599173071004306	[38]	[61,28,48]	-4	hSpCas9	negative selection	7872030
90947434	90947457	14	-	27260156	NCIH2009	viability	TGCCCTCGAACATCTCCACAAGG	RPS6KA5	ENSG00000100784	1.0635006925418968	[470]	[1271,1169,1664]	9	hSpCas9	negative selection	7872031
90978465	90978488	14	+	27260156	NCIH2009	viability	CATACAGCTTTCCAGTATCATGG	RPS6KA5	ENSG00000100784	0.596718272326977	[311]	[1140,425,508]	7	hSpCas9	negative selection	7872032
90978397	90978420	14	+	27260156	NCIH2009	viability	TTCTGTCCTTGTATGCTCTGTGG	RPS6KA5	ENSG00000100784	-0.12342687024823806	[927]	[1575,1298,767]	-2	hSpCas9	negative selection	7936283
91001079	91001102	14	+	27260156	NCIH2009	viability	AAGACTTACCTCCAGTTCCTAGG	RPS6KA5	ENSG00000100784	0.3556462023903628	[1409]	[2968,2326,2353]	5	hSpCas9	negative selection	7936284
90978304	90978327	14	+	27260156	NCIH2009	viability	ACCTAAAATGAGATGAAGTTTGG	RPS6KA5	ENSG00000100784	-0.11973435700009949	[204]	[274,352,162]	-2	hSpCas9	negative selection	7936285
90947431	90947454	14	+	27260156	NCIH1373	viability	TTACCTTGTGGAGATGTTCGAGG	RPS6KA5	ENSG00000100784	-0.34426372297999785	[38]	[78,28,13,5]	-3	hSpCas9	negative selection	7993281
90947434	90947457	14	-	27260156	NCIH1373	viability	TGCCCTCGAACATCTCCACAAGG	RPS6KA5	ENSG00000100784	0.3180507137939214	[470]	[954,446,753,139]	3	hSpCas9	negative selection	7993282
90978465	90978488	14	+	27260156	NCIH1373	viability	CATACAGCTTTCCAGTATCATGG	RPS6KA5	ENSG00000100784	0.33491205812319064	[311]	[450,293,722,77]	3	hSpCas9	negative selection	7993283
90978397	90978420	14	+	27260156	NCIH1373	viability	TTCTGTCCTTGTATGCTCTGTGG	RPS6KA5	ENSG00000100784	-0.10408664573002813	[927]	[894,1095,810,274]	-1	hSpCas9	negative selection	8057534
91001079	91001102	14	+	27260156	NCIH1373	viability	AAGACTTACCTCCAGTTCCTAGG	RPS6KA5	ENSG00000100784	0.30881219408395744	[1409]	[2023,1232,2008,705]	3	hSpCas9	negative selection	8057535
90978304	90978327	14	+	27260156	NCIH1373	viability	ACCTAAAATGAGATGAAGTTTGG	RPS6KA5	ENSG00000100784	0.41309701652174813	[204]	[364,124,379,100]	4	hSpCas9	negative selection	8057536
90947431	90947454	14	+	27260156	PATU8902	viability	TTACCTTGTGGAGATGTTCGAGG	RPS6KA5	ENSG00000100784	0.8640212321397058	[38]	[10,68,88,246]	8	hSpCas9	negative selection	8114532
90947434	90947457	14	-	27260156	PATU8902	viability	TGCCCTCGAACATCTCCACAAGG	RPS6KA5	ENSG00000100784	0.6766689709655165	[470]	[794,1444,800,1235]	7	hSpCas9	negative selection	8114533
90978465	90978488	14	+	27260156	PATU8902	viability	CATACAGCTTTCCAGTATCATGG	RPS6KA5	ENSG00000100784	0.3173029929326179	[311]	[385,760,536,472]	3	hSpCas9	negative selection	8114534
90978397	90978420	14	+	27260156	PATU8902	viability	TTCTGTCCTTGTATGCTCTGTGG	RPS6KA5	ENSG00000100784	0.40869335678634544	[927]	[1262,2059,1670,1894]	4	hSpCas9	negative selection	8178785
91001079	91001102	14	+	27260156	PATU8902	viability	AAGACTTACCTCCAGTTCCTAGG	RPS6KA5	ENSG00000100784	0.535593666629254	[1409]	[3118,2555,2201,3757]	5	hSpCas9	negative selection	8178786
90978304	90978327	14	+	27260156	PATU8902	viability	ACCTAAAATGAGATGAAGTTTGG	RPS6KA5	ENSG00000100784	0.9111558750283407	[204]	[646,467,432,631]	8	hSpCas9	negative selection	8178787
90947431	90947454	14	+	27260156	PANC1	viability	TTACCTTGTGGAGATGTTCGAGG	RPS6KA5	ENSG00000100784	0.7497439271769362	[38]	[74,159,9,7]	9	hSpCas9	negative selection	8235783
90947434	90947457	14	-	27260156	PANC1	viability	TGCCCTCGAACATCTCCACAAGG	RPS6KA5	ENSG00000100784	0.44582615022433975	[470]	[522,632,650,426]	7	hSpCas9	negative selection	8235784
90978465	90978488	14	+	27260156	PANC1	viability	CATACAGCTTTCCAGTATCATGG	RPS6KA5	ENSG00000100784	0.32464425286708015	[311]	[328,359,331,322]	5	hSpCas9	negative selection	8235785
90978397	90978420	14	+	27260156	PANC1	viability	TTCTGTCCTTGTATGCTCTGTGG	RPS6KA5	ENSG00000100784	0.1581294038260922	[927]	[998,1307,826,548]	2	hSpCas9	negative selection	8300036
91001079	91001102	14	+	27260156	PANC1	viability	AAGACTTACCTCCAGTTCCTAGG	RPS6KA5	ENSG00000100784	0.2760510039574382	[1409]	[1411,1833,1529,1188]	4	hSpCas9	negative selection	8300037
90978304	90978327	14	+	27260156	PANC1	viability	ACCTAAAATGAGATGAAGTTTGG	RPS6KA5	ENSG00000100784	-0.13490548333533758	[204]	[150,158,123,197]	-2	hSpCas9	negative selection	8300038
90947431	90947454	14	+	27260156	PANC0813	viability	TTACCTTGTGGAGATGTTCGAGG	RPS6KA5	ENSG00000100784	-0.6374261260926799	[38]	[8,47,31,26]	-7	hSpCas9	negative selection	8357034
90947434	90947457	14	-	27260156	PANC0813	viability	TGCCCTCGAACATCTCCACAAGG	RPS6KA5	ENSG00000100784	0.6574701749699012	[470]	[1064,854,812,778]	9	hSpCas9	negative selection	8357035
90978465	90978488	14	+	27260156	PANC0813	viability	CATACAGCTTTCCAGTATCATGG	RPS6KA5	ENSG00000100784	0.5426766281348145	[311]	[442,481,636,562]	8	hSpCas9	negative selection	8357036
90978397	90978420	14	+	27260156	PANC0813	viability	TTCTGTCCTTGTATGCTCTGTGG	RPS6KA5	ENSG00000100784	-0.3036701403863862	[927]	[961,1002,715,857]	-5	hSpCas9	negative selection	8421287
91001079	91001102	14	+	27260156	PANC0813	viability	AAGACTTACCTCCAGTTCCTAGG	RPS6KA5	ENSG00000100784	0.3691128580090661	[1409]	[2584,2063,1930,2019]	6	hSpCas9	negative selection	8421288
90978304	90978327	14	+	27260156	PANC0813	viability	ACCTAAAATGAGATGAAGTTTGG	RPS6KA5	ENSG00000100784	-0.3928782336823331	[204]	[323,153,138,131]	-6	hSpCas9	negative selection	8421289
90947431	90947454	14	+	27260156	RDES	viability	TTACCTTGTGGAGATGTTCGAGG	RPS6KA5	ENSG00000100784	0.40404659367964824	[38]	[55,74,71,26]	6	hSpCas9	negative selection	8478285
90947434	90947457	14	-	27260156	RDES	viability	TGCCCTCGAACATCTCCACAAGG	RPS6KA5	ENSG00000100784	0.2620499350024345	[470]	[516,549,743,838]	4	hSpCas9	negative selection	8478286
90978465	90978488	14	+	27260156	RDES	viability	CATACAGCTTTCCAGTATCATGG	RPS6KA5	ENSG00000100784	0.23521473130916004	[311]	[327,455,307,628]	4	hSpCas9	negative selection	8478287
90978397	90978420	14	+	27260156	RDES	viability	TTCTGTCCTTGTATGCTCTGTGG	RPS6KA5	ENSG00000100784	0.039532832674923246	[927]	[973,1078,1223,1109]	0	hSpCas9	negative selection	8542538
91001079	91001102	14	+	27260156	RDES	viability	AAGACTTACCTCCAGTTCCTAGG	RPS6KA5	ENSG00000100784	0.18775509094940257	[1409]	[1464,1604,2142,2307]	3	hSpCas9	negative selection	8542539
90978304	90978327	14	+	27260156	RDES	viability	ACCTAAAATGAGATGAAGTTTGG	RPS6KA5	ENSG00000100784	0.032918807750211165	[204]	[252,218,226,258]	0	hSpCas9	negative selection	8542540
90947431	90947454	14	+	27260156	PC3	viability	TTACCTTGTGGAGATGTTCGAGG	RPS6KA5	ENSG00000100784	-1.211296627676501	[38]	[5,25,9,25]	-9	hSpCas9	negative selection	8599536
90947434	90947457	14	-	27260156	PC3	viability	TGCCCTCGAACATCTCCACAAGG	RPS6KA5	ENSG00000100784	0.44161418024086224	[470]	[397,615,1184,607]	8	hSpCas9	negative selection	8599537
90978465	90978488	14	+	27260156	PC3	viability	CATACAGCTTTCCAGTATCATGG	RPS6KA5	ENSG00000100784	0.42062252033109676	[311]	[284,182,959,480]	8	hSpCas9	negative selection	8599538
90978397	90978420	14	+	27260156	PC3	viability	TTCTGTCCTTGTATGCTCTGTGG	RPS6KA5	ENSG00000100784	-0.03053074725274829	[927]	[795,534,1466,998]	0	hSpCas9	negative selection	8663789
91001079	91001102	14	+	27260156	PC3	viability	AAGACTTACCTCCAGTTCCTAGG	RPS6KA5	ENSG00000100784	0.24741276859783268	[1409]	[1014,1557,3080,1706]	5	hSpCas9	negative selection	8663790
90978304	90978327	14	+	27260156	PC3	viability	ACCTAAAATGAGATGAAGTTTGG	RPS6KA5	ENSG00000100784	-0.23747773104976377	[204]	[93,124,252,279]	-5	hSpCas9	negative selection	8663791
90947431	90947454	14	+	27260156	PATU8988T	viability	TTACCTTGTGGAGATGTTCGAGG	RPS6KA5	ENSG00000100784	0.7720040524614662	[38]	[100,37,3,116]	9	hSpCas9	negative selection	8720787
90947434	90947457	14	-	27260156	PATU8988T	viability	TGCCCTCGAACATCTCCACAAGG	RPS6KA5	ENSG00000100784	0.3356896187436712	[470]	[706,479,460,647]	6	hSpCas9	negative selection	8720788
90978465	90978488	14	+	27260156	PATU8988T	viability	CATACAGCTTTCCAGTATCATGG	RPS6KA5	ENSG00000100784	0.5894157312360796	[311]	[390,523,393,517]	8	hSpCas9	negative selection	8720789
90978397	90978420	14	+	27260156	PATU8988T	viability	TTCTGTCCTTGTATGCTCTGTGG	RPS6KA5	ENSG00000100784	-0.03312499637207822	[927]	[792,854,663,1221]	0	hSpCas9	negative selection	8785040
91001079	91001102	14	+	27260156	PATU8988T	viability	AAGACTTACCTCCAGTTCCTAGG	RPS6KA5	ENSG00000100784	0.301705154742427	[1409]	[1507,1900,1360,1997]	5	hSpCas9	negative selection	8785041
90978304	90978327	14	+	27260156	PATU8988T	viability	ACCTAAAATGAGATGAAGTTTGG	RPS6KA5	ENSG00000100784	0.19204955488989395	[204]	[319,276,115,195]	3	hSpCas9	negative selection	8785042
90947431	90947454	14	+	27260156	T47D	viability	TTACCTTGTGGAGATGTTCGAGG	RPS6KA5	ENSG00000100784	-0.5326827577142854	[38]	[31,16,38,38]	-8	hSpCas9	negative selection	8842038
90947434	90947457	14	-	27260156	T47D	viability	TGCCCTCGAACATCTCCACAAGG	RPS6KA5	ENSG00000100784	0.27707573378184264	[470]	[587,674,771,619]	6	hSpCas9	negative selection	8842039
90978465	90978488	14	+	27260156	T47D	viability	CATACAGCTTTCCAGTATCATGG	RPS6KA5	ENSG00000100784	0.27348566463485796	[311]	[497,448,425,381]	6	hSpCas9	negative selection	8842040
90978397	90978420	14	+	27260156	T47D	viability	TTCTGTCCTTGTATGCTCTGTGG	RPS6KA5	ENSG00000100784	0.0058932952991692655	[927]	[1120,879,1166,1193]	0	hSpCas9	negative selection	8906291
91001079	91001102	14	+	27260156	T47D	viability	AAGACTTACCTCCAGTTCCTAGG	RPS6KA5	ENSG00000100784	0.2552134727512927	[1409]	[1982,1945,1948,1964]	5	hSpCas9	negative selection	8906292
90978304	90978327	14	+	27260156	T47D	viability	ACCTAAAATGAGATGAAGTTTGG	RPS6KA5	ENSG00000100784	-0.19095517776280202	[204]	[181,235,173,243]	-4	hSpCas9	negative selection	8906293
90947431	90947454	14	+	27260156	SU8686	viability	TTACCTTGTGGAGATGTTCGAGG	RPS6KA5	ENSG00000100784	-0.7221434483602209	[38]	[34,20,26,6]	-8	hSpCas9	negative selection	8963289
90947434	90947457	14	-	27260156	SU8686	viability	TGCCCTCGAACATCTCCACAAGG	RPS6KA5	ENSG00000100784	0.762659648760697	[470]	[570,775,958,907]	9	hSpCas9	negative selection	8963290
90978465	90978488	14	+	27260156	SU8686	viability	CATACAGCTTTCCAGTATCATGG	RPS6KA5	ENSG00000100784	0.5403176502971296	[311]	[392,349,574,510]	8	hSpCas9	negative selection	8963291
90978397	90978420	14	+	27260156	SU8686	viability	TTCTGTCCTTGTATGCTCTGTGG	RPS6KA5	ENSG00000100784	-0.323997368869553	[927]	[757,469,911,849]	-5	hSpCas9	negative selection	9027542
91001079	91001102	14	+	27260156	SU8686	viability	AAGACTTACCTCCAGTTCCTAGG	RPS6KA5	ENSG00000100784	0.25133843885802687	[1409]	[1458,1530,1627,2142]	4	hSpCas9	negative selection	9027543
90978304	90978327	14	+	27260156	SU8686	viability	ACCTAAAATGAGATGAAGTTTGG	RPS6KA5	ENSG00000100784	-0.3241267897057023	[204]	[112,135,183,236]	-5	hSpCas9	negative selection	9027544
90947431	90947454	14	+	27260156	SKES1	viability	TTACCTTGTGGAGATGTTCGAGG	RPS6KA5	ENSG00000100784	0.5547664520012852	[38]	[18,62,41,94]	9	hSpCas9	negative selection	9084540
90947434	90947457	14	-	27260156	SKES1	viability	TGCCCTCGAACATCTCCACAAGG	RPS6KA5	ENSG00000100784	0.4426799004500155	[470]	[608,878,532,561]	8	hSpCas9	negative selection	9084541
90978465	90978488	14	+	27260156	SKES1	viability	CATACAGCTTTCCAGTATCATGG	RPS6KA5	ENSG00000100784	0.3893580912996718	[311]	[607,525,285,266]	7	hSpCas9	negative selection	9084542
90978397	90978420	14	+	27260156	SKES1	viability	TTCTGTCCTTGTATGCTCTGTGG	RPS6KA5	ENSG00000100784	-0.0779701391920532	[927]	[942,950,700,918]	-2	hSpCas9	negative selection	9148793
91001079	91001102	14	+	27260156	SKES1	viability	AAGACTTACCTCCAGTTCCTAGG	RPS6KA5	ENSG00000100784	0.311266160085822	[1409]	[1755,2320,1424,1557]	6	hSpCas9	negative selection	9148794
90978304	90978327	14	+	27260156	SKES1	viability	ACCTAAAATGAGATGAAGTTTGG	RPS6KA5	ENSG00000100784	-0.1862242469052029	[204]	[203,131,173,201]	-4	hSpCas9	negative selection	9148795
90947431	90947454	14	+	27260156	TOV112D	viability	TTACCTTGTGGAGATGTTCGAGG	RPS6KA5	ENSG00000100784	1.1246423466454316	[38]	[45,20,7,241]	9	hSpCas9	negative selection	9205791
90947434	90947457	14	-	27260156	TOV112D	viability	TGCCCTCGAACATCTCCACAAGG	RPS6KA5	ENSG00000100784	-0.04411622851199392	[470]	[378,635,406,444]	-1	hSpCas9	negative selection	9205792
90978465	90978488	14	+	27260156	TOV112D	viability	CATACAGCTTTCCAGTATCATGG	RPS6KA5	ENSG00000100784	0.37757428564088474	[311]	[470,630,246,336]	7	hSpCas9	negative selection	9205793
90978397	90978420	14	+	27260156	TOV112D	viability	TTCTGTCCTTGTATGCTCTGTGG	RPS6KA5	ENSG00000100784	-0.1492976128323903	[927]	[839,905,828,793]	-3	hSpCas9	negative selection	9270044
91001079	91001102	14	+	27260156	TOV112D	viability	AAGACTTACCTCCAGTTCCTAGG	RPS6KA5	ENSG00000100784	0.28530764526914965	[1409]	[1630,2579,1481,1400]	5	hSpCas9	negative selection	9270045
90978304	90978327	14	+	27260156	TOV112D	viability	ACCTAAAATGAGATGAAGTTTGG	RPS6KA5	ENSG00000100784	0.3659241199425891	[204]	[207,310,186,355]	7	hSpCas9	negative selection	9270046
90947431	90947454	14	+	27260156	TC71	viability	TTACCTTGTGGAGATGTTCGAGG	RPS6KA5	ENSG00000100784	-0.4715272330292244	[38]	[41,21,10,46]	-8	hSpCas9	negative selection	9327042
90947434	90947457	14	-	27260156	TC71	viability	TGCCCTCGAACATCTCCACAAGG	RPS6KA5	ENSG00000100784	0.537279846605201	[470]	[825,702,606,800]	9	hSpCas9	negative selection	9327043
90978465	90978488	14	+	27260156	TC71	viability	CATACAGCTTTCCAGTATCATGG	RPS6KA5	ENSG00000100784	0.22353013124781812	[311]	[403,373,328,460]	5	hSpCas9	negative selection	9327044
90978397	90978420	14	+	27260156	TC71	viability	TTCTGTCCTTGTATGCTCTGTGG	RPS6KA5	ENSG00000100784	0.1106688257549081	[927]	[1266,977,1135,897]	3	hSpCas9	negative selection	9391295
91001079	91001102	14	+	27260156	TC71	viability	AAGACTTACCTCCAGTTCCTAGG	RPS6KA5	ENSG00000100784	0.17850666602606768	[1409]	[1930,1598,1744,1550]	4	hSpCas9	negative selection	9391296
90978304	90978327	14	+	27260156	TC71	viability	ACCTAAAATGAGATGAAGTTTGG	RPS6KA5	ENSG00000100784	-0.032448231965833685	[204]	[207,142,271,235]	-1	hSpCas9	negative selection	9391297
90947431	90947454	14	+	27260156	TC32	viability	TTACCTTGTGGAGATGTTCGAGG	RPS6KA5	ENSG00000100784	0.034712826185780976	[38]	[17,23,67,51]	0	hSpCas9	negative selection	9448293
90947434	90947457	14	-	27260156	TC32	viability	TGCCCTCGAACATCTCCACAAGG	RPS6KA5	ENSG00000100784	0.2898408080709598	[470]	[487,404,721,610]	5	hSpCas9	negative selection	9448294
90978465	90978488	14	+	27260156	TC32	viability	CATACAGCTTTCCAGTATCATGG	RPS6KA5	ENSG00000100784	0.01409454367215024	[311]	[285,224,311,378]	0	hSpCas9	negative selection	9448295
90978397	90978420	14	+	27260156	TC32	viability	TTCTGTCCTTGTATGCTCTGTGG	RPS6KA5	ENSG00000100784	-0.3051608650142059	[927]	[718,295,1127,879]	-5	hSpCas9	negative selection	9512546
91001079	91001102	14	+	27260156	TC32	viability	AAGACTTACCTCCAGTTCCTAGG	RPS6KA5	ENSG00000100784	0.22134509698964555	[1409]	[1578,1195,1824,1666]	4	hSpCas9	negative selection	9512547
90978304	90978327	14	+	27260156	TC32	viability	ACCTAAAATGAGATGAAGTTTGG	RPS6KA5	ENSG00000100784	0.014900982098865256	[204]	[177,167,240,199]	0	hSpCas9	negative selection	9512548
90872076	90872099	14	+	27869803	HPAFII	viability after 27 days	AAGCTACTGAGTCCGAGAACTGG	RPS6KA5	ENSG00000100784	0.25699752810126353	[537]	[439,252,NaN]	2	hSpCas9	negative selection	9552707
90875294	90875317	14	-	27869803	HPAFII	viability after 27 days	AAGTTTGACGTGTACCAGCGCGG	RPS6KA5	ENSG00000100784	0.33907846453645707	[370]	[297,203,NaN]	2	hSpCas9	negative selection	9552708
90890600	90890623	14	-	27869803	HPAFII	viability after 27 days	ATTTGCACGGCTAAAGCCACCGG	RPS6KA5	ENSG00000100784	-0.5782440697460451	[78]	[35,20,NaN]	-4	hSpCas9	negative selection	9552709
90894427	90894450	14	-	27869803	HPAFII	viability after 27 days	TGATGTTGGAGTGGTGCACAGGG	RPS6KA5	ENSG00000100784	0.015384624570046149	[225]	[172,75,NaN]	0	hSpCas9	negative selection	9552710
90900707	90900730	14	+	27869803	HPAFII	viability after 27 days	TAGGATGGAAGGAGCAACAAAGG	RPS6KA5	ENSG00000100784	0.13893959058987881	[328]	[298,99,NaN]	1	hSpCas9	negative selection	9552711
90923112	90923135	14	-	27869803	HPAFII	viability after 27 days	GGGAGATTCAGGACATGACAAGG	RPS6KA5	ENSG00000100784	0.5162049770829098	[154]	[103,126,NaN]	4	hSpCas9	negative selection	9552712
90872076	90872099	14	+	27869803	HPAFII	viability after 15 days	AAGCTACTGAGTCCGAGAACTGG	RPS6KA5	ENSG00000100784	0.30926173093693454	[537]	[1115,467,NaN]	3	hSpCas9	negative selection	9635156
90875294	90875317	14	-	27869803	HPAFII	viability after 15 days	AAGTTTGACGTGTACCAGCGCGG	RPS6KA5	ENSG00000100784	0.3804883975216429	[370]	[724,390,NaN]	4	hSpCas9	negative selection	9635157
90890600	90890623	14	-	27869803	HPAFII	viability after 15 days	ATTTGCACGGCTAAAGCCACCGG	RPS6KA5	ENSG00000100784	0.26644347593449913	[78]	[193,44,NaN]	3	hSpCas9	negative selection	9635158
90894427	90894450	14	-	27869803	HPAFII	viability after 15 days	TGATGTTGGAGTGGTGCACAGGG	RPS6KA5	ENSG00000100784	0.3109983629422176	[225]	[333,280,NaN]	3	hSpCas9	negative selection	9635159
90900707	90900730	14	+	27869803	HPAFII	viability after 15 days	TAGGATGGAAGGAGCAACAAAGG	RPS6KA5	ENSG00000100784	0.05855097743396431	[328]	[522,271,NaN]	0	hSpCas9	negative selection	9635160
90923112	90923135	14	-	27869803	HPAFII	viability after 15 days	GGGAGATTCAGGACATGACAAGG	RPS6KA5	ENSG00000100784	0.5539984866216779	[154]	[267,229,NaN]	6	hSpCas9	negative selection	9635161
90872076	90872099	14	+	27869803	ASPC1	viability after 36 days	AAGCTACTGAGTCCGAGAACTGG	RPS6KA5	ENSG00000100784	-0.1610078120640983	[1474]	[277,570,495]	-2	hSpCas9	negative selection	9717605
90875294	90875317	14	-	27869803	ASPC1	viability after 36 days	AAGTTTGACGTGTACCAGCGCGG	RPS6KA5	ENSG00000100784	0.1812596583185455	[973]	[263,495,378]	1	hSpCas9	negative selection	9717606
90890600	90890623	14	-	27869803	ASPC1	viability after 36 days	ATTTGCACGGCTAAAGCCACCGG	RPS6KA5	ENSG00000100784	0.7557097480019935	[228]	[100,205,100]	7	hSpCas9	negative selection	9717607
90894427	90894450	14	-	27869803	ASPC1	viability after 36 days	TGATGTTGGAGTGGTGCACAGGG	RPS6KA5	ENSG00000100784	1.004424244542326	[686]	[611,498,369]	8	hSpCas9	negative selection	9717608
90900707	90900730	14	+	27869803	ASPC1	viability after 36 days	TAGGATGGAAGGAGCAACAAAGG	RPS6KA5	ENSG00000100784	0.3270815624708453	[699]	[365,368,211]	3	hSpCas9	negative selection	9717609
90923112	90923135	14	-	27869803	ASPC1	viability after 36 days	GGGAGATTCAGGACATGACAAGG	RPS6KA5	ENSG00000100784	1.0937270976116122	[475]	[175,466,386]	8	hSpCas9	negative selection	9717610
90872076	90872099	14	+	27869803	PATU8988S	viability after 35 days	AAGCTACTGAGTCCGAGAACTGG	RPS6KA5	ENSG00000100784	0.08678458013578694	[1140]	[500,474,NaN]	1	hSpCas9	negative selection	9800054
90875294	90875317	14	-	27869803	PATU8988S	viability after 35 days	AAGTTTGACGTGTACCAGCGCGG	RPS6KA5	ENSG00000100784	-0.5317891887067042	[898]	[225,274,NaN]	-5	hSpCas9	negative selection	9800055
90890600	90890623	14	-	27869803	PATU8988S	viability after 35 days	ATTTGCACGGCTAAAGCCACCGG	RPS6KA5	ENSG00000100784	0.0873162395864	[123]	[77,27,NaN]	1	hSpCas9	negative selection	9800056
90894427	90894450	14	-	27869803	PATU8988S	viability after 35 days	TGATGTTGGAGTGGTGCACAGGG	RPS6KA5	ENSG00000100784	0.8292587460821633	[853]	[443,778,NaN]	8	hSpCas9	negative selection	9800057
90900707	90900730	14	+	27869803	PATU8988S	viability after 35 days	TAGGATGGAAGGAGCAACAAAGG	RPS6KA5	ENSG00000100784	-0.32326395573573313	[634]	[163,244,NaN]	-3	hSpCas9	negative selection	9800058
90923112	90923135	14	-	27869803	PATU8988S	viability after 35 days	GGGAGATTCAGGACATGACAAGG	RPS6KA5	ENSG00000100784	0.1016638638604137	[316]	[133,139,NaN]	1	hSpCas9	negative selection	9800059
90872076	90872099	14	+	27869803	PATU8988S	viability after 31 days	AAGCTACTGAGTCCGAGAACTGG	RPS6KA5	ENSG00000100784	0.15908168147177015	[1140]	[529,479,NaN]	2	hSpCas9	negative selection	9882503
90875294	90875317	14	-	27869803	PATU8988S	viability after 31 days	AAGTTTGACGTGTACCAGCGCGG	RPS6KA5	ENSG00000100784	-0.36163570503818554	[898]	[234,334,NaN]	-4	hSpCas9	negative selection	9882504
90890600	90890623	14	-	27869803	PATU8988S	viability after 31 days	ATTTGCACGGCTAAAGCCACCGG	RPS6KA5	ENSG00000100784	0.6562463922848845	[123]	[91,59,NaN]	7	hSpCas9	negative selection	9882505
90894427	90894450	14	-	27869803	PATU8988S	viability after 31 days	TGATGTTGGAGTGGTGCACAGGG	RPS6KA5	ENSG00000100784	0.7202843741146209	[853]	[465,681,NaN]	8	hSpCas9	negative selection	9882506
90900707	90900730	14	+	27869803	PATU8988S	viability after 31 days	TAGGATGGAAGGAGCAACAAAGG	RPS6KA5	ENSG00000100784	-0.739277510952709	[634]	[141,163,NaN]	-7	hSpCas9	negative selection	9882507
90923112	90923135	14	-	27869803	PATU8988S	viability after 31 days	GGGAGATTCAGGACATGACAAGG	RPS6KA5	ENSG00000100784	0.4814579045591021	[316]	[157,199,NaN]	6	hSpCas9	negative selection	9882508
90872076	90872099	14	+	27869803	HPAFII	viability after 35 days	AAGCTACTGAGTCCGAGAACTGG	RPS6KA5	ENSG00000100784	0.2985072937892719	[537]	[389,272,NaN]	2	hSpCas9	negative selection	9964952
90875294	90875317	14	-	27869803	HPAFII	viability after 35 days	AAGTTTGACGTGTACCAGCGCGG	RPS6KA5	ENSG00000100784	0.053880280642424005	[370]	[241,141,NaN]	0	hSpCas9	negative selection	9964953
90890600	90890623	14	-	27869803	HPAFII	viability after 35 days	ATTTGCACGGCTAAAGCCACCGG	RPS6KA5	ENSG00000100784	-0.42606004006938036	[78]	[33,24,NaN]	-3	hSpCas9	negative selection	9964954
90894427	90894450	14	-	27869803	HPAFII	viability after 35 days	TGATGTTGGAGTGGTGCACAGGG	RPS6KA5	ENSG00000100784	0.026707445870038676	[225]	[156,70,NaN]	0	hSpCas9	negative selection	9964955
90900707	90900730	14	+	27869803	HPAFII	viability after 35 days	TAGGATGGAAGGAGCAACAAAGG	RPS6KA5	ENSG00000100784	0.22220175771840178	[328]	[301,72,NaN]	1	hSpCas9	negative selection	9964956
90923112	90923135	14	-	27869803	HPAFII	viability after 35 days	GGGAGATTCAGGACATGACAAGG	RPS6KA5	ENSG00000100784	0.979142397454098	[154]	[109,204,NaN]	6	hSpCas9	negative selection	9964957
90872076	90872099	14	+	27869803	HPAFII	viability after 31 days	AAGCTACTGAGTCCGAGAACTGG	RPS6KA5	ENSG00000100784	0.5458892508024287	[537]	[547,323,NaN]	4	hSpCas9	negative selection	10047401
90875294	90875317	14	-	27869803	HPAFII	viability after 31 days	AAGTTTGACGTGTACCAGCGCGG	RPS6KA5	ENSG00000100784	0.013175311048137628	[370]	[223,194,NaN]	0	hSpCas9	negative selection	10047402
90890600	90890623	14	-	27869803	HPAFII	viability after 31 days	ATTTGCACGGCTAAAGCCACCGG	RPS6KA5	ENSG00000100784	0.004397296022367714	[78]	[54,32,NaN]	0	hSpCas9	negative selection	10047403
90894427	90894450	14	-	27869803	HPAFII	viability after 31 days	TGATGTTGGAGTGGTGCACAGGG	RPS6KA5	ENSG00000100784	0.44507781118485823	[225]	[209,131,NaN]	3	hSpCas9	negative selection	10047404
90900707	90900730	14	+	27869803	HPAFII	viability after 31 days	TAGGATGGAAGGAGCAACAAAGG	RPS6KA5	ENSG00000100784	0.3726391287445181	[328]	[351,115,NaN]	2	hSpCas9	negative selection	10047405
90923112	90923135	14	-	27869803	HPAFII	viability after 31 days	GGGAGATTCAGGACATGACAAGG	RPS6KA5	ENSG00000100784	0.3992378786357598	[154]	[74,157,NaN]	3	hSpCas9	negative selection	10047406
90923112	90923135	14	-	28162770	P31FUJ	viability	GGGAGATTCAGGACATGACAAGG	RPS6KA5	ENSG00000100784	0.06265367911179259	[285]	[350]	0	hSpCas9	negative selection	10228111
90900190	90900213	14	-	28162770	P31FUJ	viability	AGATTTGAAGGACAAACCCCTGG	RPS6KA5	ENSG00000100784	0.1297678749703295	[132]	[170]	1	hSpCas9	negative selection	10228112
90899372	90899395	14	-	28162770	P31FUJ	viability	ACAGCTCTGAAACTCTGTGAAGG	RPS6KA5	ENSG00000100784	0.9783454597544468	[91]	[212]	9	hSpCas9	negative selection	10228113
91001130	91001153	14	-	28162770	P31FUJ	viability	GACAGGACATGCTGAGAAGGTGG	RPS6KA5	ENSG00000100784	0.3451227455668435	[273]	[408]	4	hSpCas9	negative selection	10228114
91001087	91001110	14	-	28162770	P31FUJ	viability	CTGAAGGTCCTAGGAACTGGAGG	RPS6KA5	ENSG00000100784	0.4436218478167768	[437]	[699]	5	hSpCas9	negative selection	10228115
90894546	90894569	14	-	28162770	P31FUJ	viability	GTGATGGAACTTCTGAATGGAGG	RPS6KA5	ENSG00000100784	0.12300678314876135	[403]	[516]	1	hSpCas9	negative selection	10228116
90894412	90894435	14	-	28162770	P31FUJ	viability	GCACAGGGATCTGAAACCTGAGG	RPS6KA5	ENSG00000100784	0.401069896787724	[57]	[89]	4	hSpCas9	negative selection	10228117
90943107	90943130	14	+	28162770	P31FUJ	viability	CAAAATCTGTCAGCACCACATGG	RPS6KA5	ENSG00000100784	0.9598428735280174	[230]	[527]	9	hSpCas9	negative selection	10228118
90923112	90923135	14	-	28162770	TF1	viability	GGGAGATTCAGGACATGACAAGG	RPS6KA5	ENSG00000100784	NaN	[NaN]	[349]	1	hSpCas9	negative selection	10397477
90900190	90900213	14	-	28162770	TF1	viability	AGATTTGAAGGACAAACCCCTGG	RPS6KA5	ENSG00000100784	NaN	[NaN]	[154]	1	hSpCas9	negative selection	10397478
90899372	90899395	14	-	28162770	TF1	viability	ACAGCTCTGAAACTCTGTGAAGG	RPS6KA5	ENSG00000100784	NaN	[NaN]	[154]	1	hSpCas9	negative selection	10397479
91001130	91001153	14	-	28162770	TF1	viability	GACAGGACATGCTGAGAAGGTGG	RPS6KA5	ENSG00000100784	NaN	[NaN]	[210]	1	hSpCas9	negative selection	10397480
91001087	91001110	14	-	28162770	TF1	viability	CTGAAGGTCCTAGGAACTGGAGG	RPS6KA5	ENSG00000100784	NaN	[NaN]	[287]	1	hSpCas9	negative selection	10397481
90894546	90894569	14	-	28162770	TF1	viability	GTGATGGAACTTCTGAATGGAGG	RPS6KA5	ENSG00000100784	NaN	[NaN]	[348]	1	hSpCas9	negative selection	10397482
90894412	90894435	14	-	28162770	TF1	viability	GCACAGGGATCTGAAACCTGAGG	RPS6KA5	ENSG00000100784	NaN	[NaN]	[11]	1	hSpCas9	negative selection	10397483
90943107	90943130	14	+	28162770	TF1	viability	CAAAATCTGTCAGCACCACATGG	RPS6KA5	ENSG00000100784	NaN	[NaN]	[267]	1	hSpCas9	negative selection	10397484
90923112	90923135	14	-	28162770	SKM1	viability	GGGAGATTCAGGACATGACAAGG	RPS6KA5	ENSG00000100784	0.5124173410485537	[68]	[173]	5	hSpCas9	negative selection	10566843
90900190	90900213	14	-	28162770	SKM1	viability	AGATTTGAAGGACAAACCCCTGG	RPS6KA5	ENSG00000100784	0.8928410852460607	[45]	[150]	8	hSpCas9	negative selection	10566844
90899372	90899395	14	-	28162770	SKM1	viability	ACAGCTCTGAAACTCTGTGAAGG	RPS6KA5	ENSG00000100784	0.6413988228182373	[32]	[90]	6	hSpCas9	negative selection	10566845
91001130	91001153	14	-	28162770	SKM1	viability	GACAGGACATGCTGAGAAGGTGG	RPS6KA5	ENSG00000100784	0.41503749927884404	[97]	[230]	4	hSpCas9	negative selection	10566846
91001087	91001110	14	-	28162770	SKM1	viability	CTGAAGGTCCTAGGAACTGGAGG	RPS6KA5	ENSG00000100784	0.7167377859385049	[73]	[214]	7	hSpCas9	negative selection	10566847
90894546	90894569	14	-	28162770	SKM1	viability	GTGATGGAACTTCTGAATGGAGG	RPS6KA5	ENSG00000100784	-0.05497886999961954	[113]	[193]	0	hSpCas9	negative selection	10566848
90894412	90894435	14	-	28162770	SKM1	viability	GCACAGGGATCTGAAACCTGAGG	RPS6KA5	ENSG00000100784	0.3384629741712406	[16]	[37]	3	hSpCas9	negative selection	10566849
90943107	90943130	14	+	28162770	SKM1	viability	CAAAATCTGTCAGCACCACATGG	RPS6KA5	ENSG00000100784	0.07108309806148258	[48]	[90]	0	hSpCas9	negative selection	10566850
90923112	90923135	14	-	28162770	SKM1	viability	GGGAGATTCAGGACATGACAAGG	RPS6KA5	ENSG00000100784	0.5124173410485537	[68]	[173]	5	hSpCas9	negative selection	10736209
90900190	90900213	14	-	28162770	SKM1	viability	AGATTTGAAGGACAAACCCCTGG	RPS6KA5	ENSG00000100784	0.8928410852460607	[45]	[150]	8	hSpCas9	negative selection	10736210
90899372	90899395	14	-	28162770	SKM1	viability	ACAGCTCTGAAACTCTGTGAAGG	RPS6KA5	ENSG00000100784	0.6413988228182373	[32]	[90]	6	hSpCas9	negative selection	10736211
91001130	91001153	14	-	28162770	SKM1	viability	GACAGGACATGCTGAGAAGGTGG	RPS6KA5	ENSG00000100784	0.41503749927884404	[97]	[230]	4	hSpCas9	negative selection	10736212
91001087	91001110	14	-	28162770	SKM1	viability	CTGAAGGTCCTAGGAACTGGAGG	RPS6KA5	ENSG00000100784	0.7167377859385049	[73]	[214]	7	hSpCas9	negative selection	10736213
90894546	90894569	14	-	28162770	SKM1	viability	GTGATGGAACTTCTGAATGGAGG	RPS6KA5	ENSG00000100784	-0.05497886999961954	[113]	[193]	0	hSpCas9	negative selection	10736214
90894412	90894435	14	-	28162770	SKM1	viability	GCACAGGGATCTGAAACCTGAGG	RPS6KA5	ENSG00000100784	0.3384629741712406	[16]	[37]	3	hSpCas9	negative selection	10736215
90943107	90943130	14	+	28162770	SKM1	viability	CAAAATCTGTCAGCACCACATGG	RPS6KA5	ENSG00000100784	0.07108309806148258	[48]	[90]	0	hSpCas9	negative selection	10736216
90923112	90923135	14	-	28162770	PL21	viability	GGGAGATTCAGGACATGACAAGG	RPS6KA5	ENSG00000100784	1.6090510109713223	[176]	[234]	9	hSpCas9	negative selection	10905575
90900190	90900213	14	-	28162770	PL21	viability	AGATTTGAAGGACAAACCCCTGG	RPS6KA5	ENSG00000100784	1.0688950812110676	[137]	[125]	8	hSpCas9	negative selection	10905576
90899372	90899395	14	-	28162770	PL21	viability	ACAGCTCTGAAACTCTGTGAAGG	RPS6KA5	ENSG00000100784	0.015715043351892888	[99]	[43]	0	hSpCas9	negative selection	10905577
91001130	91001153	14	-	28162770	PL21	viability	GACAGGACATGCTGAGAAGGTGG	RPS6KA5	ENSG00000100784	-0.12001721554584932	[406]	[162]	-1	hSpCas9	negative selection	10905578
91001087	91001110	14	-	28162770	PL21	viability	CTGAAGGTCCTAGGAACTGGAGG	RPS6KA5	ENSG00000100784	-0.04778789895426527	[322]	[135]	0	hSpCas9	negative selection	10905579
90894546	90894569	14	-	28162770	PL21	viability	GTGATGGAACTTCTGAATGGAGG	RPS6KA5	ENSG00000100784	0.4717170211020447	[448]	[270]	4	hSpCas9	negative selection	10905580
90894412	90894435	14	-	28162770	PL21	viability	GCACAGGGATCTGAAACCTGAGG	RPS6KA5	ENSG00000100784	0.2694022769264337	[60]	[31]	2	hSpCas9	negative selection	10905581
90943107	90943130	14	+	28162770	PL21	viability	CAAAATCTGTCAGCACCACATGG	RPS6KA5	ENSG00000100784	0.7535320362096067	[153]	[112]	6	hSpCas9	negative selection	10905582
90923112	90923135	14	-	28162770	P31FUJ	viability	GGGAGATTCAGGACATGACAAGG	RPS6KA5	ENSG00000100784	0.06265367911179259	[285]	[350]	0	hSpCas9	negative selection	11074941
90900190	90900213	14	-	28162770	P31FUJ	viability	AGATTTGAAGGACAAACCCCTGG	RPS6KA5	ENSG00000100784	0.1297678749703295	[132]	[170]	1	hSpCas9	negative selection	11074942
90899372	90899395	14	-	28162770	P31FUJ	viability	ACAGCTCTGAAACTCTGTGAAGG	RPS6KA5	ENSG00000100784	0.9783454597544468	[91]	[212]	9	hSpCas9	negative selection	11074943
91001130	91001153	14	-	28162770	P31FUJ	viability	GACAGGACATGCTGAGAAGGTGG	RPS6KA5	ENSG00000100784	0.3451227455668435	[273]	[408]	4	hSpCas9	negative selection	11074944
91001087	91001110	14	-	28162770	P31FUJ	viability	CTGAAGGTCCTAGGAACTGGAGG	RPS6KA5	ENSG00000100784	0.4436218478167768	[437]	[699]	5	hSpCas9	negative selection	11074945
90894546	90894569	14	-	28162770	P31FUJ	viability	GTGATGGAACTTCTGAATGGAGG	RPS6KA5	ENSG00000100784	0.12300678314876135	[403]	[516]	1	hSpCas9	negative selection	11074946
90894412	90894435	14	-	28162770	P31FUJ	viability	GCACAGGGATCTGAAACCTGAGG	RPS6KA5	ENSG00000100784	0.401069896787724	[57]	[89]	4	hSpCas9	negative selection	11074947
90943107	90943130	14	+	28162770	P31FUJ	viability	CAAAATCTGTCAGCACCACATGG	RPS6KA5	ENSG00000100784	0.9598428735280174	[230]	[527]	9	hSpCas9	negative selection	11074948
90923112	90923135	14	-	28162770	OCIAML5	viability	GGGAGATTCAGGACATGACAAGG	RPS6KA5	ENSG00000100784	-0.10050360048483287	[176]	[297]	0	hSpCas9	negative selection	11244307
90900190	90900213	14	-	28162770	OCIAML5	viability	AGATTTGAAGGACAAACCCCTGG	RPS6KA5	ENSG00000100784	-0.25751802131364265	[99]	[150]	-2	hSpCas9	negative selection	11244308
90899372	90899395	14	-	28162770	OCIAML5	viability	ACAGCTCTGAAACTCTGTGAAGG	RPS6KA5	ENSG00000100784	1.342949411541146	[37]	[173]	9	hSpCas9	negative selection	11244309
91001130	91001153	14	-	28162770	OCIAML5	viability	GACAGGACATGCTGAGAAGGTGG	RPS6KA5	ENSG00000100784	0.27902496437170377	[204]	[448]	2	hSpCas9	negative selection	11244310
91001087	91001110	14	-	28162770	OCIAML5	viability	CTGAAGGTCCTAGGAACTGGAGG	RPS6KA5	ENSG00000100784	0.4181854892510426	[215]	[520]	3	hSpCas9	negative selection	11244311
90894546	90894569	14	-	28162770	OCIAML5	viability	GTGATGGAACTTCTGAATGGAGG	RPS6KA5	ENSG00000100784	-0.10204482387234426	[241]	[406]	0	hSpCas9	negative selection	11244312
90894412	90894435	14	-	28162770	OCIAML5	viability	GCACAGGGATCTGAAACCTGAGG	RPS6KA5	ENSG00000100784	0.5438621054671424	[37]	[99]	5	hSpCas9	negative selection	11244313
90943107	90943130	14	+	28162770	OCIAML5	viability	CAAAATCTGTCAGCACCACATGG	RPS6KA5	ENSG00000100784	0.5523236842153382	[169]	[449]	5	hSpCas9	negative selection	11244314
90923112	90923135	14	-	28162770	EOL1	viability	GGGAGATTCAGGACATGACAAGG	RPS6KA5	ENSG00000100784	1.2423479808352207	[279]	[348]	9	hSpCas9	negative selection	11413673
90900190	90900213	14	-	28162770	EOL1	viability	AGATTTGAAGGACAAACCCCTGG	RPS6KA5	ENSG00000100784	0.3325648431716062	[308]	[204]	3	hSpCas9	negative selection	11413674
90899372	90899395	14	-	28162770	EOL1	viability	ACAGCTCTGAAACTCTGTGAAGG	RPS6KA5	ENSG00000100784	0.7676789229536685	[164]	[147]	6	hSpCas9	negative selection	11413675
91001130	91001153	14	-	28162770	EOL1	viability	GACAGGACATGCTGAGAAGGTGG	RPS6KA5	ENSG00000100784	0.9090901768303367	[562]	[556]	7	hSpCas9	negative selection	11413676
91001087	91001110	14	-	28162770	EOL1	viability	CTGAAGGTCCTAGGAACTGGAGG	RPS6KA5	ENSG00000100784	-0.03570604963670895	[357]	[183]	0	hSpCas9	negative selection	11413677
90894546	90894569	14	-	28162770	EOL1	viability	GTGATGGAACTTCTGAATGGAGG	RPS6KA5	ENSG00000100784	-0.2576555596502145	[471]	[207]	-2	hSpCas9	negative selection	11413678
90894412	90894435	14	-	28162770	EOL1	viability	GCACAGGGATCTGAAACCTGAGG	RPS6KA5	ENSG00000100784	-0.07545222842946542	[71]	[35]	0	hSpCas9	negative selection	11413679
90943107	90943130	14	+	28162770	EOL1	viability	CAAAATCTGTCAGCACCACATGG	RPS6KA5	ENSG00000100784	-0.08217809161777884	[214]	[106]	0	hSpCas9	negative selection	11413680
90923112	90923135	14	-	28162770	MOLM13	viability	GGGAGATTCAGGACATGACAAGG	RPS6KA5	ENSG00000100784	1.1125964678587965	[338]	[529]	8	hSpCas9	negative selection	11583039
90900190	90900213	14	-	28162770	MOLM13	viability	AGATTTGAAGGACAAACCCCTGG	RPS6KA5	ENSG00000100784	1.1329704481374556	[250]	[397]	8	hSpCas9	negative selection	11583040
90899372	90899395	14	-	28162770	MOLM13	viability	ACAGCTCTGAAACTCTGTGAAGG	RPS6KA5	ENSG00000100784	2.6716845840036965	[144]	[667]	9	hSpCas9	negative selection	11583041
91001130	91001153	14	-	28162770	MOLM13	viability	GACAGGACATGCTGAGAAGGTGG	RPS6KA5	ENSG00000100784	-0.02777743764394558	[508]	[360]	0	hSpCas9	negative selection	11583042
91001087	91001110	14	-	28162770	MOLM13	viability	CTGAAGGTCCTAGGAACTGGAGG	RPS6KA5	ENSG00000100784	0.29598673066182385	[364]	[323]	2	hSpCas9	negative selection	11583043
90894546	90894569	14	-	28162770	MOLM13	viability	GTGATGGAACTTCTGAATGGAGG	RPS6KA5	ENSG00000100784	-0.33356493907334095	[609]	[349]	-2	hSpCas9	negative selection	11583044
90894412	90894435	14	-	28162770	MOLM13	viability	GCACAGGGATCTGAAACCTGAGG	RPS6KA5	ENSG00000100784	-1.3716459462621748	[67]	[18]	-6	hSpCas9	negative selection	11583045
90943107	90943130	14	+	28162770	MOLM13	viability	CAAAATCTGTCAGCACCACATGG	RPS6KA5	ENSG00000100784	-0.2544065238247422	[423]	[256]	-1	hSpCas9	negative selection	11583046
90923112	90923135	14	-	28162770	HEL	viability	GGGAGATTCAGGACATGACAAGG	RPS6KA5	ENSG00000100784	0.12758169031385436	[352]	[246]	1	hSpCas9	negative selection	11752405
90900190	90900213	14	-	28162770	HEL	viability	AGATTTGAAGGACAAACCCCTGG	RPS6KA5	ENSG00000100784	-0.19125121656071375	[204]	[114]	-1	hSpCas9	negative selection	11752406
90899372	90899395	14	-	28162770	HEL	viability	ACAGCTCTGAAACTCTGTGAAGG	RPS6KA5	ENSG00000100784	1.4999040538289021	[121]	[220]	9	hSpCas9	negative selection	11752407
91001130	91001153	14	-	28162770	HEL	viability	GACAGGACATGCTGAGAAGGTGG	RPS6KA5	ENSG00000100784	0.8142952879203709	[490]	[552]	7	hSpCas9	negative selection	11752408
91001087	91001110	14	-	28162770	HEL	viability	CTGAAGGTCCTAGGAACTGGAGG	RPS6KA5	ENSG00000100784	-0.03347273108675275	[309]	[193]	0	hSpCas9	negative selection	11752409
90894546	90894569	14	-	28162770	HEL	viability	GTGATGGAACTTCTGAATGGAGG	RPS6KA5	ENSG00000100784	0.1598745188979369	[449]	[321]	1	hSpCas9	negative selection	11752410
90894412	90894435	14	-	28162770	HEL	viability	GCACAGGGATCTGAAACCTGAGG	RPS6KA5	ENSG00000100784	0.3115329235249842	[38]	[30]	2	hSpCas9	negative selection	11752411
90943107	90943130	14	+	28162770	HEL	viability	CAAAATCTGTCAGCACCACATGG	RPS6KA5	ENSG00000100784	0.9110289632856461	[273]	[329]	7	hSpCas9	negative selection	11752412
90923112	90923135	14	-	28162770	MV411	viability	GGGAGATTCAGGACATGACAAGG	RPS6KA5	ENSG00000100784	0.5369441679777601	[242]	[296]	5	hSpCas9	negative selection	11921771
90900190	90900213	14	-	28162770	MV411	viability	AGATTTGAAGGACAAACCCCTGG	RPS6KA5	ENSG00000100784	0.2720996050170444	[173]	[176]	2	hSpCas9	negative selection	11921772
90899372	90899395	14	-	28162770	MV411	viability	ACAGCTCTGAAACTCTGTGAAGG	RPS6KA5	ENSG00000100784	0.9393152554204435	[90]	[146]	8	hSpCas9	negative selection	11921773
91001130	91001153	14	-	28162770	MV411	viability	GACAGGACATGCTGAGAAGGTGG	RPS6KA5	ENSG00000100784	-0.4504428354100428	[351]	[216]	-3	hSpCas9	negative selection	11921774
91001087	91001110	14	-	28162770	MV411	viability	CTGAAGGTCCTAGGAACTGGAGG	RPS6KA5	ENSG00000100784	0.2250697377543207	[324]	[319]	2	hSpCas9	negative selection	11921775
90894546	90894569	14	-	28162770	MV411	viability	GTGATGGAACTTCTGAATGGAGG	RPS6KA5	ENSG00000100784	0.9532248341072361	[289]	[472]	8	hSpCas9	negative selection	11921776
90894412	90894435	14	-	28162770	MV411	viability	GCACAGGGATCTGAAACCTGAGG	RPS6KA5	ENSG00000100784	-0.8196766450757615	[43]	[20]	-5	hSpCas9	negative selection	11921777
90943107	90943130	14	+	28162770	MV411	viability	CAAAATCTGTCAGCACCACATGG	RPS6KA5	ENSG00000100784	0.647975480366504	[174]	[230]	6	hSpCas9	negative selection	11921778
90923112	90923135	14	-	28162770	MONOMAC1	viability	GGGAGATTCAGGACATGACAAGG	RPS6KA5	ENSG00000100784	0.24165192028393534	[120]	[163]	2	hSpCas9	negative selection	12091137
90900190	90900213	14	-	28162770	MONOMAC1	viability	AGATTTGAAGGACAAACCCCTGG	RPS6KA5	ENSG00000100784	-0.7308604987889087	[96]	[66]	-5	hSpCas9	negative selection	12091138
90899372	90899395	14	-	28162770	MONOMAC1	viability	ACAGCTCTGAAACTCTGTGAAGG	RPS6KA5	ENSG00000100784	0.2335975072703087	[45]	[61]	2	hSpCas9	negative selection	12091139
91001130	91001153	14	-	28162770	MONOMAC1	viability	GACAGGACATGCTGAGAAGGTGG	RPS6KA5	ENSG00000100784	0.21800065221928988	[248]	[331]	2	hSpCas9	negative selection	12091140
91001087	91001110	14	-	28162770	MONOMAC1	viability	CTGAAGGTCCTAGGAACTGGAGG	RPS6KA5	ENSG00000100784	0.42147821337262903	[169]	[260]	4	hSpCas9	negative selection	12091141
90894546	90894569	14	-	28162770	MONOMAC1	viability	GTGATGGAACTTCTGAATGGAGG	RPS6KA5	ENSG00000100784	0.7903078521344172	[228]	[453]	7	hSpCas9	negative selection	12091142
90894412	90894435	14	-	28162770	MONOMAC1	viability	GCACAGGGATCTGAAACCTGAGG	RPS6KA5	ENSG00000100784	0.20350108252417476	[24]	[32]	2	hSpCas9	negative selection	12091143
90943107	90943130	14	+	28162770	MONOMAC1	viability	CAAAATCTGTCAGCACCACATGG	RPS6KA5	ENSG00000100784	0.4098182595104446	[108]	[165]	4	hSpCas9	negative selection	12091144
90923112	90923135	14	-	28162770	OCIAML2	viability	GGGAGATTCAGGACATGACAAGG	RPS6KA5	ENSG00000100784	-0.17689862218545083	[61]	[303]	-1	hSpCas9	negative selection	12260503
90900190	90900213	14	-	28162770	OCIAML2	viability	AGATTTGAAGGACAAACCCCTGG	RPS6KA5	ENSG00000100784	0.4274905607386251	[32]	[245]	4	hSpCas9	negative selection	12260504
90899372	90899395	14	-	28162770	OCIAML2	viability	ACAGCTCTGAAACTCTGTGAAGG	RPS6KA5	ENSG00000100784	1.2635586842534712	[12]	[172]	9	hSpCas9	negative selection	12260505
91001130	91001153	14	-	28162770	OCIAML2	viability	GACAGGACATGCTGAGAAGGTGG	RPS6KA5	ENSG00000100784	0.07430578160741852	[66]	[390]	0	hSpCas9	negative selection	12260506
91001087	91001110	14	-	28162770	OCIAML2	viability	CTGAAGGTCCTAGGAACTGGAGG	RPS6KA5	ENSG00000100784	0.3961036438943747	[50]	[371]	4	hSpCas9	negative selection	12260507
90894546	90894569	14	-	28162770	OCIAML2	viability	GTGATGGAACTTCTGAATGGAGG	RPS6KA5	ENSG00000100784	0.2424375012266804	[69]	[458]	2	hSpCas9	negative selection	12260508
90894412	90894435	14	-	28162770	OCIAML2	viability	GCACAGGGATCTGAAACCTGAGG	RPS6KA5	ENSG00000100784	-2.608133348992096	[10]	[9]	-8	hSpCas9	negative selection	12260509
90943107	90943130	14	+	28162770	OCIAML2	viability	CAAAATCTGTCAGCACCACATGG	RPS6KA5	ENSG00000100784	0.35453637293190354	[22]	[162]	3	hSpCas9	negative selection	12260510
90923112	90923135	14	-	28162770	OCIAML3	viability	GGGAGATTCAGGACATGACAAGG	RPS6KA5	ENSG00000100784	0.622803748748985	[73]	[343]	5	hSpCas9	negative selection	12429869
90900190	90900213	14	-	28162770	OCIAML3	viability	AGATTTGAAGGACAAACCCCTGG	RPS6KA5	ENSG00000100784	-0.3960682627122543	[50]	[116]	-3	hSpCas9	negative selection	12429870
90899372	90899395	14	-	28162770	OCIAML3	viability	ACAGCTCTGAAACTCTGTGAAGG	RPS6KA5	ENSG00000100784	-1.0236919155674082	[32]	[48]	-6	hSpCas9	negative selection	12429871
91001130	91001153	14	-	28162770	OCIAML3	viability	GACAGGACATGCTGAGAAGGTGG	RPS6KA5	ENSG00000100784	-0.4240826388818509	[91]	[206]	-3	hSpCas9	negative selection	12429872
91001087	91001110	14	-	28162770	OCIAML3	viability	CTGAAGGTCCTAGGAACTGGAGG	RPS6KA5	ENSG00000100784	0.22591074319735338	[97]	[345]	2	hSpCas9	negative selection	12429873
90894546	90894569	14	-	28162770	OCIAML3	viability	GTGATGGAACTTCTGAATGGAGG	RPS6KA5	ENSG00000100784	0.30977704441653353	[92]	[347]	3	hSpCas9	negative selection	12429874
90894412	90894435	14	-	28162770	OCIAML3	viability	GCACAGGGATCTGAAACCTGAGG	RPS6KA5	ENSG00000100784	-0.6429172408051096	[14]	[28]	-5	hSpCas9	negative selection	12429875
90943107	90943130	14	+	28162770	OCIAML3	viability	CAAAATCTGTCAGCACCACATGG	RPS6KA5	ENSG00000100784	0.6550875745517569	[64]	[308]	6	hSpCas9	negative selection	12429876