| 14281688 | 14281711 | 11 | - | 26472758 | Jiyoye | viability | AAGAAGGACAACAGTTAGCACGG | RRAS2 | ENSG00000133818 | -0.275872118897472 | [638] | [397] | -2 | hSpCas9 | negative selection | 140571 | 14294785 | 14294808 | 11 | - | 26472758 | Jiyoye | viability | GACTGGCGAAGGCTTCCTGTTGG | RRAS2 | ENSG00000133818 | -0.6498555635305054 | [128] | [61] | -5 | hSpCas9 | negative selection | 140572 | 14281711 | 14281734 | 11 | - | 26472758 | Jiyoye | viability | GTTGGAATTTCAGGTAACACAGG | RRAS2 | ENSG00000133818 | 0.37198595304357346 | [165] | [161] | 3 | hSpCas9 | negative selection | 140573 | 14281678 | 14281701 | 11 | - | 26472758 | Jiyoye | viability | ACAGTTAGCACGGCAGCTTAAGG | RRAS2 | ENSG00000133818 | 0.5807389600115336 | [351] | [396] | 4 | hSpCas9 | negative selection | 140574 | 14294832 | 14294855 | 11 | - | 26472758 | Jiyoye | viability | ACAGCAGGACAAGAAGAGTTTGG | RRAS2 | ENSG00000133818 | -0.14351721713053664 | [103] | [70] | -1 | hSpCas9 | negative selection | 140575 | 14358813 | 14358836 | 11 | - | 26472758 | Jiyoye | viability | GGAGAAGTACCGGCTCGTGGTGG | RRAS2 | ENSG00000133818 | 0.40717538150587346 | [125] | [125] | 3 | hSpCas9 | negative selection | 140576 | 14358861 | 14358884 | 11 | - | 26472758 | Jiyoye | viability | CTGTAGCGTCCCCATGGCCGCGG | RRAS2 | ENSG00000133818 | 0.8959225669677264 | [123] | [173] | 6 | hSpCas9 | negative selection | 140577 | 14358823 | 14358846 | 11 | - | 26472758 | Jiyoye | viability | GCTCCGGCCAGGAGAAGTACCGG | RRAS2 | ENSG00000133818 | 0.4288704526051923 | [131] | [133] | 3 | hSpCas9 | negative selection | 140578 | 14358757 | 14358780 | 11 | + | 26472758 | Jiyoye | viability | AGGTACCTGGATGAACTGGATGG | RRAS2 | ENSG00000133818 | 0.2627854721706986 | [104] | [94] | 2 | hSpCas9 | negative selection | 140579 | 14281663 | 14281686 | 11 | - | 26472758 | Jiyoye | viability | GCTTAAGGTAACATACATGGAGG | RRAS2 | ENSG00000133818 | 1.1956712763121615 | [10] | [18] | 7 | hSpCas9 | negative selection | 140580 | 14281688 | 14281711 | 11 | - | 26472758 | KBM7 | viability | AAGAAGGACAACAGTTAGCACGG | RRAS2 | ENSG00000133818 | 0.2833773150329637 | [1933,1345] | [1268,618] | 3 | hSpCas9 | negative selection | 331689 | 14294785 | 14294808 | 11 | - | 26472758 | KBM7 | viability | GACTGGCGAAGGCTTCCTGTTGG | RRAS2 | ENSG00000133818 | -1.7792682452000137 | [567,479] | [42,96] | -8 | hSpCas9 | negative selection | 331690 | 14281711 | 14281734 | 11 | - | 26472758 | KBM7 | viability | GTTGGAATTTCAGGTAACACAGG | RRAS2 | ENSG00000133818 | 3.3499130301856193 | [1091,878] | [9080,773] | 9 | hSpCas9 | negative selection | 331691 | 14281678 | 14281701 | 11 | - | 26472758 | KBM7 | viability | ACAGTTAGCACGGCAGCTTAAGG | RRAS2 | ENSG00000133818 | 0.6719797519561597 | [1931,1397] | [1262,1205] | 7 | hSpCas9 | negative selection | 331692 | 14294832 | 14294855 | 11 | - | 26472758 | KBM7 | viability | ACAGCAGGACAAGAAGAGTTTGG | RRAS2 | ENSG00000133818 | 0.45354762002268567 | [620,295] | [267,301] | 5 | hSpCas9 | negative selection | 331693 | 14358813 | 14358836 | 11 | - | 26472758 | KBM7 | viability | GGAGAAGTACCGGCTCGTGGTGG | RRAS2 | ENSG00000133818 | 0.888920212605961 | [380,246] | [244,289] | 8 | hSpCas9 | negative selection | 331694 | 14358861 | 14358884 | 11 | - | 26472758 | KBM7 | viability | CTGTAGCGTCCCCATGGCCGCGG | RRAS2 | ENSG00000133818 | 1.0661325983951015 | [919,663] | [843,704] | 9 | hSpCas9 | negative selection | 331695 | 14358823 | 14358846 | 11 | - | 26472758 | KBM7 | viability | GCTCCGGCCAGGAGAAGTACCGG | RRAS2 | ENSG00000133818 | 0.6813949611698114 | [785,734] | [691,468] | 7 | hSpCas9 | negative selection | 331696 | 14358757 | 14358780 | 11 | + | 26472758 | KBM7 | viability | AGGTACCTGGATGAACTGGATGG | RRAS2 | ENSG00000133818 | -0.021486112120009282 | [498,561] | [277,221] | 0 | hSpCas9 | negative selection | 331697 | 14281663 | 14281686 | 11 | - | 26472758 | KBM7 | viability | GCTTAAGGTAACATACATGGAGG | RRAS2 | ENSG00000133818 | -0.4393576156534771 | [97,134] | [45,36] | -4 | hSpCas9 | negative selection | 331698 | 14281688 | 14281711 | 11 | - | 26472758 | Raji | viability | AAGAAGGACAACAGTTAGCACGG | RRAS2 | ENSG00000133818 | 0.09383700353565194 | [641] | [158] | 0 | hSpCas9 | negative selection | 522807 | 14294785 | 14294808 | 11 | - | 26472758 | Raji | viability | GACTGGCGAAGGCTTCCTGTTGG | RRAS2 | ENSG00000133818 | -0.3632462898685617 | [193] | [34] | -3 | hSpCas9 | negative selection | 522808 | 14281711 | 14281734 | 11 | - | 26472758 | Raji | viability | GTTGGAATTTCAGGTAACACAGG | RRAS2 | ENSG00000133818 | 1.071759625642878 | [327] | [159] | 8 | hSpCas9 | negative selection | 522809 | 14281678 | 14281701 | 11 | - | 26472758 | Raji | viability | ACAGTTAGCACGGCAGCTTAAGG | RRAS2 | ENSG00000133818 | 0.5407218513953871 | [704] | [237] | 5 | hSpCas9 | negative selection | 522810 | 14294832 | 14294855 | 11 | - | 26472758 | Raji | viability | ACAGCAGGACAAGAAGAGTTTGG | RRAS2 | ENSG00000133818 | -0.8225380288902602 | [220] | [28] | -6 | hSpCas9 | negative selection | 522811 | 14358813 | 14358836 | 11 | - | 26472758 | Raji | viability | GGAGAAGTACCGGCTCGTGGTGG | RRAS2 | ENSG00000133818 | 0.43600628283497006 | [171] | [53] | 4 | hSpCas9 | negative selection | 522812 | 14358861 | 14358884 | 11 | - | 26472758 | Raji | viability | CTGTAGCGTCCCCATGGCCGCGG | RRAS2 | ENSG00000133818 | 0.32484978540203413 | [460] | [133] | 3 | hSpCas9 | negative selection | 522813 | 14358823 | 14358846 | 11 | - | 26472758 | Raji | viability | GCTCCGGCCAGGAGAAGTACCGG | RRAS2 | ENSG00000133818 | 0.47650519959708504 | [414] | [133] | 4 | hSpCas9 | negative selection | 522814 | 14358757 | 14358780 | 11 | + | 26472758 | Raji | viability | AGGTACCTGGATGAACTGGATGG | RRAS2 | ENSG00000133818 | -0.4997747114617528 | [261] | [42] | -4 | hSpCas9 | negative selection | 522815 | 14281663 | 14281686 | 11 | - | 26472758 | Raji | viability | GCTTAAGGTAACATACATGGAGG | RRAS2 | ENSG00000133818 | 0.48289267046580564 | [36] | [11] | 4 | hSpCas9 | negative selection | 522816 | 14281688 | 14281711 | 11 | - | 26472758 | K562 | viability | AAGAAGGACAACAGTTAGCACGG | RRAS2 | ENSG00000133818 | 0.9862942359564597 | [1583] | [2648] | 8 | hSpCas9 | negative selection | 713925 | 14294785 | 14294808 | 11 | - | 26472758 | K562 | viability | GACTGGCGAAGGCTTCCTGTTGG | RRAS2 | ENSG00000133818 | -1.6679057539926998 | [398] | [105] | -7 | hSpCas9 | negative selection | 713926 | 14281711 | 14281734 | 11 | - | 26472758 | K562 | viability | GTTGGAATTTCAGGTAACACAGG | RRAS2 | ENSG00000133818 | 1.3096118239120402 | [648] | [1357] | 9 | hSpCas9 | negative selection | 713927 | 14281678 | 14281701 | 11 | - | 26472758 | K562 | viability | ACAGTTAGCACGGCAGCTTAAGG | RRAS2 | ENSG00000133818 | 0.432950347198543 | [1360] | [1550] | 3 | hSpCas9 | negative selection | 713928 | 14294832 | 14294855 | 11 | - | 26472758 | K562 | viability | ACAGCAGGACAAGAAGAGTTTGG | RRAS2 | ENSG00000133818 | 1.0141211082446526 | [304] | [519] | 8 | hSpCas9 | negative selection | 713929 | 14358813 | 14358836 | 11 | - | 26472758 | K562 | viability | GGAGAAGTACCGGCTCGTGGTGG | RRAS2 | ENSG00000133818 | -0.20929923977645684 | [440] | [321] | -1 | hSpCas9 | negative selection | 713930 | 14358861 | 14358884 | 11 | - | 26472758 | K562 | viability | CTGTAGCGTCCCCATGGCCGCGG | RRAS2 | ENSG00000133818 | 0.9210414161420148 | [497] | [795] | 7 | hSpCas9 | negative selection | 713931 | 14358823 | 14358846 | 11 | - | 26472758 | K562 | viability | GCTCCGGCCAGGAGAAGTACCGG | RRAS2 | ENSG00000133818 | 1.0301633557683374 | [662] | [1142] | 8 | hSpCas9 | negative selection | 713932 | 14358757 | 14358780 | 11 | + | 26472758 | K562 | viability | AGGTACCTGGATGAACTGGATGG | RRAS2 | ENSG00000133818 | 0.3340559401511234 | [467] | [497] | 2 | hSpCas9 | negative selection | 713933 | 14281663 | 14281686 | 11 | - | 26472758 | K562 | viability | GCTTAAGGTAACATACATGGAGG | RRAS2 | ENSG00000133818 | -0.026228862277222653 | [75] | [62] | 0 | hSpCas9 | negative selection | 713934 | 14358664 | 14358687 | 11 | + | 25494202 | A375 | resistance to PLX-4720 (puromycin) | GCGCCTCTGGGGCGAGGTCGCGG | RRAS2 | ENSG00000133818 | -1.9533080802331888 | [115,25] | [2,3] | -9 | dCas9-VP64 | positive selection | 2396607 | 14358690 | 14358713 | 11 | - | 25494202 | A375 | resistance to PLX-4720 (puromycin) | TGGCGCTACCTGTGGCGGGGCGG | RRAS2 | ENSG00000133818 | -0.355320583157972 | [0,14] | [0,1] | -2 | dCas9-VP64 | positive selection | 2396608 | 14326909 | 14326932 | 11 | + | 25494202 | A375 | resistance to PLX-4720 (puromycin) | AAATTAGCCGGGCGTAGTGGCGG | RRAS2 | ENSG00000133818 | -0.8514681672512537 | [13,97] | [5,6] | -5 | dCas9-VP64 | positive selection | 2404281 | 14358621 | 14358644 | 11 | + | 25494202 | A375 | resistance to PLX-4720 (puromycin) | CCCCGCGCCCTCCCGCCCCCTGG | RRAS2 | ENSG00000133818 | -1.3527520993340196 | [367,710] | [41,50] | -7 | dCas9-VP64 | positive selection | 2407459 | 14358598 | 14358621 | 11 | + | 25494202 | A375 | resistance to PLX-4720 (puromycin) | CCGCAGGGCAGGAGCGTAGTCGG | RRAS2 | ENSG00000133818 | -0.3289876739860913 | [57,50] | [11,6] | -1 | dCas9-VP64 | positive selection | 2407460 | 14358567 | 14358590 | 11 | - | 25494202 | A375 | resistance to PLX-4720 (puromycin) | TCGCGCTCCTGCCTCCTCCCGGG | RRAS2 | ENSG00000133818 | -0.39419916068827265 | [203,363] | [29,65] | -2 | dCas9-VP64 | positive selection | 2407461 | 14305814 | 14305837 | 11 | + | 25494202 | A375 | resistance to PLX-4720 (puromycin) | GCAAGAGGATCACTTGAGCCCAG | RRAS2 | ENSG00000133818 | 0.169734143386715 | [57,44] | [12,10] | 0 | dCas9-VP64 | positive selection | 2416829 | 14359259 | 14359282 | 11 | + | 25494202 | A375 | resistance to PLX-4720 (puromycin) | CTGAGGTTCGGGAGGTAACCCGG | RRAS2 | ENSG00000133818 | 7.141398711844131 | [11,51] | [35,2078] | 9 | dCas9-VP64 | positive selection | 2441919 | 14359355 | 14359378 | 11 | + | 25494202 | A375 | resistance to PLX-4720 (puromycin) | GTCAGTTGGGAGTGGGACGAAGG | RRAS2 | ENSG00000133818 | 3.339004924281366 | [27,44] | [54,110] | 8 | dCas9-VP64 | positive selection | 2441920 | 14359304 | 14359327 | 11 | - | 25494202 | A375 | resistance to PLX-4720 (puromycin) | TCACTGGCTAGGGATTAGAGCGG | RRAS2 | ENSG00000133818 | 2.239915373213015 | [60,44] | [93,12] | 7 | dCas9-VP64 | positive selection | 2441921 | 14358664 | 14358687 | 11 | + | 25494202 | A375 | resistance to PLX-4720 (zeocin) | GCGCCTCTGGGGCGAGGTCGCGG | RRAS2 | ENSG00000133818 | 0.7912813073278601 | [57,8] | [31,6] | 5 | dCas9-VP64 | positive selection | 2491862 | 14358690 | 14358713 | 11 | - | 25494202 | A375 | resistance to PLX-4720 (zeocin) | TGGCGCTACCTGTGGCGGGGCGG | RRAS2 | ENSG00000133818 | -0.26472384298523677 | [18,16] | [4,3] | -2 | dCas9-VP64 | positive selection | 2491863 | 14326909 | 14326932 | 11 | + | 25494202 | A375 | resistance to PLX-4720 (zeocin) | AAATTAGCCGGGCGTAGTGGCGG | RRAS2 | ENSG00000133818 | 0.40157018881037165 | [169,39] | [83,8] | 3 | dCas9-VP64 | positive selection | 2499536 | 14358621 | 14358644 | 11 | + | 25494202 | A375 | resistance to PLX-4720 (zeocin) | CCCCGCGCCCTCCCGCCCCCTGG | RRAS2 | ENSG00000133818 | -0.07982383491880185 | [786,452] | [168,213] | 0 | dCas9-VP64 | positive selection | 2502714 | 14358598 | 14358621 | 11 | + | 25494202 | A375 | resistance to PLX-4720 (zeocin) | CCGCAGGGCAGGAGCGTAGTCGG | RRAS2 | ENSG00000133818 | -0.06047561647433128 | [134,105] | [44,30] | 0 | dCas9-VP64 | positive selection | 2502715 | 14358567 | 14358590 | 11 | - | 25494202 | A375 | resistance to PLX-4720 (zeocin) | TCGCGCTCCTGCCTCCTCCCGGG | RRAS2 | ENSG00000133818 | -0.1605277538769322 | [105,129] | [38,29] | -1 | dCas9-VP64 | positive selection | 2502716 | 14305814 | 14305837 | 11 | + | 25494202 | A375 | resistance to PLX-4720 (zeocin) | GCAAGAGGATCACTTGAGCCCAG | RRAS2 | ENSG00000133818 | -0.04478500742304492 | [42,58] | [7,21] | 0 | dCas9-VP64 | positive selection | 2512084 | 14359259 | 14359282 | 11 | + | 25494202 | A375 | resistance to PLX-4720 (zeocin) | CTGAGGTTCGGGAGGTAACCCGG | RRAS2 | ENSG00000133818 | 2.1967771941559957 | [49,259] | [28,417] | 8 | dCas9-VP64 | positive selection | 2537174 | 14359355 | 14359378 | 11 | + | 25494202 | A375 | resistance to PLX-4720 (zeocin) | GTCAGTTGGGAGTGGGACGAAGG | RRAS2 | ENSG00000133818 | 1.831365714421119 | [153,44] | [50,177] | 8 | dCas9-VP64 | positive selection | 2537175 | 14359304 | 14359327 | 11 | - | 25494202 | A375 | resistance to PLX-4720 (zeocin) | TCACTGGCTAGGGATTAGAGCGG | RRAS2 | ENSG00000133818 | 1.3011669278417988 | [123,289] | [233,101] | 7 | dCas9-VP64 | positive selection | 2537176 | 14294470 | 14294493 | 11 | - | 27453484 | HT29 | resistance to T3SS1-dependent cytotoxicity | AGATCTGGATCATCAAAGACAGG | RRAS2 | ENSG00000133818 | 0.15538660276631533 | [4,4] | [4,4] | 3 | hSpCas9 | positive selection | 3018070 | 14294771 | 14294794 | 11 | + | 27453484 | HT29 | resistance to T3SS1-dependent cytotoxicity | CTGTGACTGAAAAGACCAACAGG | RRAS2 | ENSG00000133818 | 0.3184406143168468 | [5,5] | [4,6] | 6 | hSpCas9 | positive selection | 3018071 | 14281711 | 14281734 | 11 | - | 27453484 | HT29 | resistance to T3SS1-dependent cytotoxicity | GTTGGAATTTCAGGTAACACAGG | RRAS2 | ENSG00000133818 | 0.5104031625630467 | [3,3] | [4,4] | 9 | hSpCas9 | positive selection | 3018072 | 14294759 | 14294782 | 11 | - | 27453484 | HT29 | resistance to T3SS1-dependent cytotoxicity | TTTCAGTCACAGATAGAGGCAGG | RRAS2 | ENSG00000133818 | 0.3867031880596916 | [4,5] | [5,6] | 7 | hSpCas9 | positive selection | 3018073 | 14294470 | 14294493 | 11 | - | 27453484 | HT29 | resistance to T3SS2-dependent cytotoxicity | AGATCTGGATCATCAAAGACAGG | RRAS2 | ENSG00000133818 | 0.15735755249290334 | [4,4] | [4,2] | 2 | hSpCas9 | positive selection | 3085928 | 14294771 | 14294794 | 11 | + | 27453484 | HT29 | resistance to T3SS2-dependent cytotoxicity | CTGTGACTGAAAAGACCAACAGG | RRAS2 | ENSG00000133818 | 0.26440902832832125 | [5,5] | [4,4] | 5 | hSpCas9 | positive selection | 3085929 | 14281711 | 14281734 | 11 | - | 27453484 | HT29 | resistance to T3SS2-dependent cytotoxicity | GTTGGAATTTCAGGTAACACAGG | RRAS2 | ENSG00000133818 | 0.22000274684532417 | [3,3] | [3,2] | 4 | hSpCas9 | positive selection | 3085930 | 14294759 | 14294782 | 11 | - | 27453484 | HT29 | resistance to T3SS2-dependent cytotoxicity | TTTCAGTCACAGATAGAGGCAGG | RRAS2 | ENSG00000133818 | 0.35361979497944007 | [4,4] | [4,4] | 6 | hSpCas9 | positive selection | 3085931 | 14295805 | 14295828 | 11 | + | 27383988 | 293T | resistance to West Nile virus (flavivirus) | CTTTGTGTAAGAATCTTCAATGG | RRAS2 | ENSG00000133818 | 1.1912370209880627 | [66,66] | [0,0] | 5 | hSpCas9 | positive selection | 3390738 | 14294807 | 14294830 | 11 | - | 27383988 | 293T | resistance to West Nile virus (flavivirus) | CCATGAGAGAACAGTATATGAGG | RRAS2 | ENSG00000133818 | 1.8997742068277512 | [40,40] | [0,0] | 7 | hSpCas9 | positive selection | 3390739 | 14294770 | 14294793 | 11 | + | 27383988 | 293T | resistance to West Nile virus (flavivirus) | CTGTGACTGAAAAGACCAACAGG | RRAS2 | ENSG00000133818 | -0.8459615969661868 | [274,274] | [0,0] | -6 | hSpCas9 | positive selection | 3390740 | 14294470 | 14294493 | 11 | - | 26780180 | HT29 | viability (Avana library 4 designs) | AGATCTGGATCATCAAAGACAGG | RRAS2 | ENSG00000133818 | 1.27088089365011 | [] | [] | 5 | hSpCas9 | negative selection | 3456453 | 14294770 | 14294793 | 11 | + | 26780180 | HT29 | viability (Avana library 4 designs) | CTGTGACTGAAAAGACCAACAGG | RRAS2 | ENSG00000133818 | 1.0455704759223 | [] | [] | 4 | hSpCas9 | negative selection | 3456454 | 14281711 | 14281734 | 11 | - | 26780180 | HT29 | viability (Avana library 4 designs) | GTTGGAATTTCAGGTAACACAGG | RRAS2 | ENSG00000133818 | 2.64099565873759 | [] | [] | 8 | hSpCas9 | negative selection | 3456455 | 14294759 | 14294782 | 11 | - | 26780180 | HT29 | viability (Avana library 4 designs) | TTTCAGTCACAGATAGAGGCAGG | RRAS2 | ENSG00000133818 | 1.89583728726817 | [] | [] | 7 | hSpCas9 | negative selection | 3456456 | 14294759 | 14294782 | 11 | - | 26780180 | A375 | viability (Avana lentiCRISPRv2) | TTTCAGTCACAGATAGAGGCAGG | RRAS2 | ENSG00000133818 | -0.382836767412694 | [] | [] | 0 | hSpCas9 | negative selection | 3554937 | 14294770 | 14294793 | 11 | + | 26780180 | A375 | viability (Avana lentiCRISPRv2) | CTGTGACTGAAAAGACCAACAGG | RRAS2 | ENSG00000133818 | -1.93137464043284 | [] | [] | -2 | hSpCas9 | negative selection | 3554938 | 14294470 | 14294493 | 11 | - | 26780180 | A375 | viability (Avana lentiCRISPRv2) | AGATCTGGATCATCAAAGACAGG | RRAS2 | ENSG00000133818 | -8.21804932790158 | [] | [] | -7 | hSpCas9 | negative selection | 3554939 | 14281711 | 14281734 | 11 | - | 26780180 | A375 | viability (Avana lentiCRISPRv2) | GTTGGAATTTCAGGTAACACAGG | RRAS2 | ENSG00000133818 | 0.493438521294429 | [] | [] | 0 | hSpCas9 | negative selection | 3554940 | 14294785 | 14294808 | 11 | - | 26780180 | A375 | viability (Avana lentiCRISPRv2) | GACTGGCGAAGGCTTCCTGTTGG | RRAS2 | ENSG00000133818 | -3.15397725451387 | [] | [] | -4 | hSpCas9 | negative selection | 3554941 | 14294796 | 14294819 | 11 | - | 26780180 | A375 | viability (Avana lentiCRISPRv2) | CAGTATATGAGGACTGGCGAAGG | RRAS2 | ENSG00000133818 | -0.202536760644127 | [] | [] | 0 | hSpCas9 | negative selection | 3554942 | 14294759 | 14294782 | 11 | - | 26780180 | A375 | viability (Avana lentiGuide) | TTTCAGTCACAGATAGAGGCAGG | RRAS2 | ENSG00000133818 | 2.27726039443158 | [] | [] | 2 | hSpCas9 | negative selection | 3663596 | 14294770 | 14294793 | 11 | + | 26780180 | A375 | viability (Avana lentiGuide) | CTGTGACTGAAAAGACCAACAGG | RRAS2 | ENSG00000133818 | 1.36843645553873 | [] | [] | 1 | hSpCas9 | negative selection | 3663597 | 14294470 | 14294493 | 11 | - | 26780180 | A375 | viability (Avana lentiGuide) | AGATCTGGATCATCAAAGACAGG | RRAS2 | ENSG00000133818 | 9.38851139717561 | [] | [] | 6 | hSpCas9 | negative selection | 3663598 | 14281711 | 14281734 | 11 | - | 26780180 | A375 | viability (Avana lentiGuide) | GTTGGAATTTCAGGTAACACAGG | RRAS2 | ENSG00000133818 | 0.610855664623442 | [] | [] | 0 | hSpCas9 | negative selection | 3663599 | 14294785 | 14294808 | 11 | - | 26780180 | A375 | viability (Avana lentiGuide) | GACTGGCGAAGGCTTCCTGTTGG | RRAS2 | ENSG00000133818 | 16.2147674559881 | [] | [] | 8 | hSpCas9 | negative selection | 3663600 | 14294796 | 14294819 | 11 | - | 26780180 | A375 | viability (Avana lentiGuide) | CAGTATATGAGGACTGGCGAAGG | RRAS2 | ENSG00000133818 | 7.4582053140904 | [] | [] | 6 | hSpCas9 | negative selection | 3663601 | 14294759 | 14294782 | 11 | - | 26780180 | A375 | resistance to vemurafenib (Avana lentiCRISPRv2) | TTTCAGTCACAGATAGAGGCAGG | RRAS2 | ENSG00000133818 | -0.16133795411992036 | [6] | [5,5] | -3 | hSpCas9 | positive selection | 3772203 | 14294770 | 14294793 | 11 | + | 26780180 | A375 | resistance to vemurafenib (Avana lentiCRISPRv2) | CTGTGACTGAAAAGACCAACAGG | RRAS2 | ENSG00000133818 | -0.6088976677584657 | [5] | [3,2] | -7 | hSpCas9 | positive selection | 3772204 | 14294470 | 14294493 | 11 | - | 26780180 | A375 | resistance to vemurafenib (Avana lentiCRISPRv2) | AGATCTGGATCATCAAAGACAGG | RRAS2 | ENSG00000133818 | -0.6895567632630607 | [8] | [5,3] | -7 | hSpCas9 | positive selection | 3772205 | 14281711 | 14281734 | 11 | - | 26780180 | A375 | resistance to vemurafenib (Avana lentiCRISPRv2) | GTTGGAATTTCAGGTAACACAGG | RRAS2 | ENSG00000133818 | 0.03262387162860319 | [5] | [5,4] | 0 | hSpCas9 | positive selection | 3772206 | 14294785 | 14294808 | 11 | - | 26780180 | A375 | resistance to vemurafenib (Avana lentiCRISPRv2) | GACTGGCGAAGGCTTCCTGTTGG | RRAS2 | ENSG00000133818 | 0.08840589396558303 | [4] | [5,5] | 2 | hSpCas9 | positive selection | 3772207 | 14294796 | 14294819 | 11 | - | 26780180 | A375 | resistance to vemurafenib (Avana lentiCRISPRv2) | CAGTATATGAGGACTGGCGAAGG | RRAS2 | ENSG00000133818 | -0.08909178409565212 | [5] | [4,4] | -1 | hSpCas9 | positive selection | 3772208 | 14294759 | 14294782 | 11 | - | 26780180 | A375 | resistance to vemurafenib (Avana lentiGuide) | TTTCAGTCACAGATAGAGGCAGG | RRAS2 | ENSG00000133818 | 0.04787204539687828 | [7] | [6,5] | 1 | hSpCas9 | positive selection | 3880810 | 14294770 | 14294793 | 11 | + | 26780180 | A375 | resistance to vemurafenib (Avana lentiGuide) | CTGTGACTGAAAAGACCAACAGG | RRAS2 | ENSG00000133818 | 0.15181505669002848 | [6] | [6,5] | 3 | hSpCas9 | positive selection | 3880811 | 14294470 | 14294493 | 11 | - | 26780180 | A375 | resistance to vemurafenib (Avana lentiGuide) | AGATCTGGATCATCAAAGACAGG | RRAS2 | ENSG00000133818 | -0.07183966674332465 | [7] | [5,5] | -1 | hSpCas9 | positive selection | 3880812 | 14281711 | 14281734 | 11 | - | 26780180 | A375 | resistance to vemurafenib (Avana lentiGuide) | GTTGGAATTTCAGGTAACACAGG | RRAS2 | ENSG00000133818 | 0.3759717248973383 | [5] | [6,5] | 9 | hSpCas9 | positive selection | 3880813 | 14294785 | 14294808 | 11 | - | 26780180 | A375 | resistance to vemurafenib (Avana lentiGuide) | GACTGGCGAAGGCTTCCTGTTGG | RRAS2 | ENSG00000133818 | -0.49946360835822784 | [5] | [2,3] | -6 | hSpCas9 | positive selection | 3880814 | 14294796 | 14294819 | 11 | - | 26780180 | A375 | resistance to vemurafenib (Avana lentiGuide) | CAGTATATGAGGACTGGCGAAGG | RRAS2 | ENSG00000133818 | -0.3988424651314065 | [4] | [3,2] | -5 | hSpCas9 | positive selection | 3880815 | 14358857 | 14358880 | 11 | - | 26780180 | A375 | viability | AGCGTCCCCATGGCCGCGGCCGG | RRAS2 | ENSG00000133818 | 0.768880950975118 | [] | [] | 3 | hSpCas9 | negative selection | 3990831 | 14295757 | 14295780 | 11 | + | 26780180 | A375 | viability | AGTTTACTTACTATCTAGCCGGG | RRAS2 | ENSG00000133818 | 1.46479588762792 | [] | [] | 8 | hSpCas9 | negative selection | 3990832 | 14294807 | 14294830 | 11 | - | 26780180 | A375 | viability | CCATGAGAGAACAGTATATGAGG | RRAS2 | ENSG00000133818 | 0.867350109284423 | [] | [] | 3 | hSpCas9 | negative selection | 3990833 | 14358804 | 14358827 | 11 | + | 26780180 | A375 | viability | CCCCGCCGACCACCACGAGCCGG | RRAS2 | ENSG00000133818 | 1.14117264520495 | [] | [] | 6 | hSpCas9 | negative selection | 3990834 | 14295805 | 14295828 | 11 | + | 26780180 | A375 | viability | CTTTGTGTAAGAATCTTCAATGG | RRAS2 | ENSG00000133818 | 1.09471147788842 | [] | [] | 5 | hSpCas9 | negative selection | 3990835 | 14358857 | 14358880 | 11 | - | 26780180 | HT29 | viability (GeCKOv2 library) | AGCGTCCCCATGGCCGCGGCCGG | RRAS2 | ENSG00000133818 | 1.11347040483292 | [] | [] | 5 | hSpCas9 | negative selection | 4098797 | 14295757 | 14295780 | 11 | + | 26780180 | HT29 | viability (GeCKOv2 library) | AGTTTACTTACTATCTAGCCGGG | RRAS2 | ENSG00000133818 | 1.51187230066607 | [] | [] | 7 | hSpCas9 | negative selection | 4098798 | 14294807 | 14294830 | 11 | - | 26780180 | HT29 | viability (GeCKOv2 library) | CCATGAGAGAACAGTATATGAGG | RRAS2 | ENSG00000133818 | 1.64659311458157 | [] | [] | 8 | hSpCas9 | negative selection | 4098799 | 14358804 | 14358827 | 11 | + | 26780180 | HT29 | viability (GeCKOv2 library) | CCCCGCCGACCACCACGAGCCGG | RRAS2 | ENSG00000133818 | 1.6818416489682 | [] | [] | 8 | hSpCas9 | negative selection | 4098800 | 14295805 | 14295828 | 11 | + | 26780180 | HT29 | viability (GeCKOv2 library) | CTTTGTGTAAGAATCTTCAATGG | RRAS2 | ENSG00000133818 | 1.36824571532339 | [] | [] | 7 | hSpCas9 | negative selection | 4098801 | 14358804 | 14358827 | 11 | + | 26780180 | A375 | resistance to vemurafenib (GeCKOv2 lentiGuide) | CCCCGCCGACCACCACGAGCCGG | RRAS2 | ENSG00000133818 | -0.0793765575663391 | [1] | [1,0] | -1 | hSpCas9 | positive selection | 4295869 | 14358857 | 14358880 | 11 | - | 26780180 | A375 | resistance to vemurafenib (GeCKOv2 lentiGuide) | AGCGTCCCCATGGCCGCGGCCGG | RRAS2 | ENSG00000133818 | 0.07274587344743824 | [2] | [2,1] | 1 | hSpCas9 | positive selection | 4295870 | 14295757 | 14295780 | 11 | + | 26780180 | A375 | resistance to vemurafenib (GeCKOv2 lentiGuide) | AGTTTACTTACTATCTAGCCGGG | RRAS2 | ENSG00000133818 | -0.5451846329793014 | [2] | [1,0] | -8 | hSpCas9 | positive selection | 4295871 | 14295805 | 14295828 | 11 | + | 26780180 | A375 | resistance to vemurafenib (GeCKOv2 lentiGuide) | CTTTGTGTAAGAATCTTCAATGG | RRAS2 | ENSG00000133818 | 0.1041763014991075 | [1] | [0,1] | 2 | hSpCas9 | positive selection | 4360123 | 14294807 | 14294830 | 11 | - | 26780180 | A375 | resistance to vemurafenib (GeCKOv2 lentiGuide) | CCATGAGAGAACAGTATATGAGG | RRAS2 | ENSG00000133818 | -0.11519359730161421 | [2] | [1,0] | -2 | hSpCas9 | positive selection | 4360124 | 14281678 | 14281700 | 11 | - | 27760321 | OCIAML3 | viability | CAGTTAGCACGGCAGCTTAAGG | RRAS2 | ENSG00000133818 | 0.45739145401902903 | [487,457] | [407,638] | 5 | hSpCas9 | negative selection | 4436064 | 14281711 | 14281733 | 11 | - | 27760321 | OCIAML3 | viability | TTGGAATTTCAGGTAACACAGG | RRAS2 | ENSG00000133818 | 0.909895315659907 | [79,70] | [72,159] | 9 | hSpCas9 | negative selection | 4436065 | 14294470 | 14294492 | 11 | - | 27760321 | OCIAML3 | viability | GATCTGGATCATCAAAGACAGG | RRAS2 | ENSG00000133818 | 0.349869932207314 | [0,0] | [0,0] | 4 | hSpCas9 | negative selection | 4436066 | 14294497 | 14294519 | 11 | + | 27760321 | OCIAML3 | viability | TATTACCAATTAAAATCATTGG | RRAS2 | ENSG00000133818 | 0.349869932207314 | [0,0] | [0,0] | 4 | hSpCas9 | negative selection | 4436067 | 14294533 | 14294555 | 11 | - | 27760321 | OCIAML3 | viability | AGACAGATTCTCAGAGTAAAGG | RRAS2 | ENSG00000133818 | -0.1471796844352098 | [134,74] | [76,66] | -1 | hSpCas9 | negative selection | 4436068 | 14294847 | 14294869 | 11 | - | 27760321 | OCIAML3 | viability | CTTTAGTTTTGGATACAGCAGG | RRAS2 | ENSG00000133818 | -0.9208254866251753 | [193,185] | [52,111] | -7 | hSpCas9 | negative selection | 4436069 | 14295758 | 14295780 | 11 | + | 27760321 | OCIAML3 | viability | GTTTACTTACTATCTAGCCGGG | RRAS2 | ENSG00000133818 | 0.8385745287538203 | [141,114] | [163,197] | 8 | hSpCas9 | negative selection | 4436070 | 14281678 | 14281700 | 11 | - | 27760321 | OCIAML2 | viability | CAGTTAGCACGGCAGCTTAAGG | RRAS2 | ENSG00000133818 | 0.46242491761796023 | [487,457] | [442,638] | 6 | hSpCas9 | negative selection | 4519527 | 14281711 | 14281733 | 11 | - | 27760321 | OCIAML2 | viability | TTGGAATTTCAGGTAACACAGG | RRAS2 | ENSG00000133818 | 0.4819777216268366 | [79,70] | [60,116] | 6 | hSpCas9 | negative selection | 4519528 | 14294470 | 14294492 | 11 | - | 27760321 | OCIAML2 | viability | GATCTGGATCATCAAAGACAGG | RRAS2 | ENSG00000133818 | 0.3011245669422653 | [0,0] | [0,0] | 4 | hSpCas9 | negative selection | 4519529 | 14294497 | 14294519 | 11 | + | 27760321 | OCIAML2 | viability | TATTACCAATTAAAATCATTGG | RRAS2 | ENSG00000133818 | 0.3011245669422653 | [0,0] | [0,0] | 4 | hSpCas9 | negative selection | 4519530 | 14294533 | 14294555 | 11 | - | 27760321 | OCIAML2 | viability | AGACAGATTCTCAGAGTAAAGG | RRAS2 | ENSG00000133818 | -0.6722376530609293 | [134,74] | [18,95] | -6 | hSpCas9 | negative selection | 4519531 | 14294847 | 14294869 | 11 | - | 27760321 | OCIAML2 | viability | CTTTAGTTTTGGATACAGCAGG | RRAS2 | ENSG00000133818 | 0.2665929761451027 | [193,185] | [157,220] | 3 | hSpCas9 | negative selection | 4519532 | 14295758 | 14295780 | 11 | + | 27760321 | OCIAML2 | viability | GTTTACTTACTATCTAGCCGGG | RRAS2 | ENSG00000133818 | 0.3939641285524509 | [141,114] | [134,136] | 5 | hSpCas9 | negative selection | 4519533 | 14281678 | 14281700 | 11 | - | 27760321 | MV411 | viability | CAGTTAGCACGGCAGCTTAAGG | RRAS2 | ENSG00000133818 | 0.9176484809098685 | [487,457] | [627,532] | 6 | hSpCas9 | negative selection | 4602990 | 14281711 | 14281733 | 11 | - | 27760321 | MV411 | viability | TTGGAATTTCAGGTAACACAGG | RRAS2 | ENSG00000133818 | 1.59416853630316 | [79,70] | [128,181] | 9 | hSpCas9 | negative selection | 4602991 | 14294470 | 14294492 | 11 | - | 27760321 | MV411 | viability | GATCTGGATCATCAAAGACAGG | RRAS2 | ENSG00000133818 | 0.5949485011219959 | [0,0] | [0,0] | 4 | hSpCas9 | negative selection | 4602992 | 14294497 | 14294519 | 11 | + | 27760321 | MV411 | viability | TATTACCAATTAAAATCATTGG | RRAS2 | ENSG00000133818 | 0.5949485011219959 | [0,0] | [0,0] | 4 | hSpCas9 | negative selection | 4602993 | 14294533 | 14294555 | 11 | - | 27760321 | MV411 | viability | AGACAGATTCTCAGAGTAAAGG | RRAS2 | ENSG00000133818 | -1.8364883814609172 | [134,74] | [30,0] | -8 | hSpCas9 | negative selection | 4602994 | 14294847 | 14294869 | 11 | - | 27760321 | MV411 | viability | CTTTAGTTTTGGATACAGCAGG | RRAS2 | ENSG00000133818 | 1.0876754946789 | [193,185] | [373,105] | 7 | hSpCas9 | negative selection | 4602995 | 14295758 | 14295780 | 11 | + | 27760321 | MV411 | viability | GTTTACTTACTATCTAGCCGGG | RRAS2 | ENSG00000133818 | 1.6040290935037005 | [141,114] | [255,256] | 9 | hSpCas9 | negative selection | 4602996 | 14281678 | 14281700 | 11 | - | 27760321 | HL60 | viability | CAGTTAGCACGGCAGCTTAAGG | RRAS2 | ENSG00000133818 | 0.5473333382156331 | [487,457] | [615,510] | 6 | hSpCas9 | negative selection | 4686453 | 14281711 | 14281733 | 11 | - | 27760321 | HL60 | viability | TTGGAATTTCAGGTAACACAGG | RRAS2 | ENSG00000133818 | 2.6535684137998974 | [79,70] | [252,529] | 9 | hSpCas9 | negative selection | 4686454 | 14294470 | 14294492 | 11 | - | 27760321 | HL60 | viability | GATCTGGATCATCAAAGACAGG | RRAS2 | ENSG00000133818 | 0.2870783393278593 | [0,0] | [0,0] | 3 | hSpCas9 | negative selection | 4686455 | 14294497 | 14294519 | 11 | + | 27760321 | HL60 | viability | TATTACCAATTAAAATCATTGG | RRAS2 | ENSG00000133818 | 0.2870783393278593 | [0,0] | [0,0] | 3 | hSpCas9 | negative selection | 4686456 | 14294533 | 14294555 | 11 | - | 27760321 | HL60 | viability | AGACAGATTCTCAGAGTAAAGG | RRAS2 | ENSG00000133818 | -1.1720509568017312 | [134,74] | [13,61] | -8 | hSpCas9 | negative selection | 4686457 | 14294847 | 14294869 | 11 | - | 27760321 | HL60 | viability | CTTTAGTTTTGGATACAGCAGG | RRAS2 | ENSG00000133818 | 4.878249609594443 | [193,185] | [5392,3700] | 9 | hSpCas9 | negative selection | 4686458 | 14295758 | 14295780 | 11 | + | 27760321 | HL60 | viability | GTTTACTTACTATCTAGCCGGG | RRAS2 | ENSG00000133818 | -0.7456776581653088 | [141,114] | [37,87] | -6 | hSpCas9 | negative selection | 4686459 | 14281678 | 14281700 | 11 | - | 27760321 | HT1080 | viability | CAGTTAGCACGGCAGCTTAAGG | RRAS2 | ENSG00000133818 | -0.29559848954731605 | [457,357] | [109,156] | -1 | hSpCas9 | negative selection | 4769916 | 14281711 | 14281733 | 11 | - | 27760321 | HT1080 | viability | TTGGAATTTCAGGTAACACAGG | RRAS2 | ENSG00000133818 | 2.402140308778494 | [70,55] | [234,22] | 9 | hSpCas9 | negative selection | 4769917 | 14294470 | 14294492 | 11 | - | 27760321 | HT1080 | viability | GATCTGGATCATCAAAGACAGG | RRAS2 | ENSG00000133818 | 1.3056276939190559 | [0,0] | [0,0] | 7 | hSpCas9 | negative selection | 4769918 | 14294497 | 14294519 | 11 | + | 27760321 | HT1080 | viability | TATTACCAATTAAAATCATTGG | RRAS2 | ENSG00000133818 | 1.3056276939190559 | [0,0] | [0,0] | 7 | hSpCas9 | negative selection | 4769919 | 14294533 | 14294555 | 11 | - | 27760321 | HT1080 | viability | AGACAGATTCTCAGAGTAAAGG | RRAS2 | ENSG00000133818 | -2.2270475437298436 | [74,58] | [9,0] | -6 | hSpCas9 | negative selection | 4769920 | 14294847 | 14294869 | 11 | - | 27760321 | HT1080 | viability | CTTTAGTTTTGGATACAGCAGG | RRAS2 | ENSG00000133818 | 0.45070388624496494 | [185,144] | [28,156] | 2 | hSpCas9 | negative selection | 4769921 | 14295758 | 14295780 | 11 | + | 27760321 | HT1080 | viability | GTTTACTTACTATCTAGCCGGG | RRAS2 | ENSG00000133818 | 2.498926620846021 | [114,89] | [290,164] | 9 | hSpCas9 | negative selection | 4769922 | 14281678 | 14281700 | 11 | - | 27760321 | HT29 | viability after 7 days | CAGTTAGCACGGCAGCTTAAGG | RRAS2 | ENSG00000133818 | 0.16830956172190656 | [457,357] | [823,635,348] | 2 | hSpCas9 | negative selection | 4853379 | 14281711 | 14281733 | 11 | - | 27760321 | HT29 | viability after 7 days | TTGGAATTTCAGGTAACACAGG | RRAS2 | ENSG00000133818 | 0.3675878463137119 | [70,55] | [155,84,82] | 5 | hSpCas9 | negative selection | 4853380 | 14294470 | 14294492 | 11 | - | 27760321 | HT29 | viability after 7 days | GATCTGGATCATCAAAGACAGG | RRAS2 | ENSG00000133818 | -0.3840325596302083 | [0,0] | [0,0,0] | -5 | hSpCas9 | negative selection | 4853381 | 14294497 | 14294519 | 11 | + | 27760321 | HT29 | viability after 7 days | TATTACCAATTAAAATCATTGG | RRAS2 | ENSG00000133818 | -0.3840325596302083 | [0,0] | [0,0,0] | -5 | hSpCas9 | negative selection | 4853382 | 14294533 | 14294555 | 11 | - | 27760321 | HT29 | viability after 7 days | AGACAGATTCTCAGAGTAAAGG | RRAS2 | ENSG00000133818 | -0.8471856566141849 | [74,58] | [74,39,32] | -8 | hSpCas9 | negative selection | 4853383 | 14294847 | 14294869 | 11 | - | 27760321 | HT29 | viability after 7 days | CTTTAGTTTTGGATACAGCAGG | RRAS2 | ENSG00000133818 | -1.47529331544234 | [185,144] | [66,112,48] | -9 | hSpCas9 | negative selection | 4853384 | 14295758 | 14295780 | 11 | + | 27760321 | HT29 | viability after 7 days | GTTTACTTACTATCTAGCCGGG | RRAS2 | ENSG00000133818 | -0.6144122225953381 | [114,89] | [100,63,94] | -7 | hSpCas9 | negative selection | 4853385 | 14281678 | 14281700 | 11 | - | 27760321 | HT29 | viability after 25 days | CAGTTAGCACGGCAGCTTAAGG | RRAS2 | ENSG00000133818 | -1.0502403799921822 | [457,357] | [219,320,123] | -6 | hSpCas9 | negative selection | 4936842 | 14281711 | 14281733 | 11 | - | 27760321 | HT29 | viability after 25 days | TTGGAATTTCAGGTAACACAGG | RRAS2 | ENSG00000133818 | 0.06487402977727053 | [70,55] | [39,96,94] | 0 | hSpCas9 | negative selection | 4936843 | 14294470 | 14294492 | 11 | - | 27760321 | HT29 | viability after 25 days | GATCTGGATCATCAAAGACAGG | RRAS2 | ENSG00000133818 | -0.21405457092746794 | [0,0] | [0,0,0] | -2 | hSpCas9 | negative selection | 4936844 | 14294497 | 14294519 | 11 | + | 27760321 | HT29 | viability after 25 days | TATTACCAATTAAAATCATTGG | RRAS2 | ENSG00000133818 | -0.21405457092746794 | [0,0] | [0,0,0] | -2 | hSpCas9 | negative selection | 4936845 | 14294533 | 14294555 | 11 | - | 27760321 | HT29 | viability after 25 days | AGACAGATTCTCAGAGTAAAGG | RRAS2 | ENSG00000133818 | -0.7771555572918483 | [74,58] | [12,69,53] | -6 | hSpCas9 | negative selection | 4936846 | 14294847 | 14294869 | 11 | - | 27760321 | HT29 | viability after 25 days | CTTTAGTTTTGGATACAGCAGG | RRAS2 | ENSG00000133818 | -0.5310915414497803 | [185,144] | [76,220,93] | -5 | hSpCas9 | negative selection | 4936847 | 14295758 | 14295780 | 11 | + | 27760321 | HT29 | viability after 25 days | GTTTACTTACTATCTAGCCGGG | RRAS2 | ENSG00000133818 | 0.16555536718250097 | [114,89] | [159,162,61] | 1 | hSpCas9 | negative selection | 4936848 | 14281678 | 14281700 | 11 | - | 27760321 | HT29 | viability after 22 days | CAGTTAGCACGGCAGCTTAAGG | RRAS2 | ENSG00000133818 | -0.43937005105397586 | [457,357] | [324,392,325] | -4 | hSpCas9 | negative selection | 5020305 | 14281711 | 14281733 | 11 | - | 27760321 | HT29 | viability after 22 days | TTGGAATTTCAGGTAACACAGG | RRAS2 | ENSG00000133818 | -0.6874690614662629 | [70,55] | [62,65,6] | -5 | hSpCas9 | negative selection | 5020306 | 14294470 | 14294492 | 11 | - | 27760321 | HT29 | viability after 22 days | GATCTGGATCATCAAAGACAGG | RRAS2 | ENSG00000133818 | -0.23137320278672746 | [0,0] | [0,0,0] | -2 | hSpCas9 | negative selection | 5020307 | 14294497 | 14294519 | 11 | + | 27760321 | HT29 | viability after 22 days | TATTACCAATTAAAATCATTGG | RRAS2 | ENSG00000133818 | -0.23137320278672746 | [0,0] | [0,0,0] | -2 | hSpCas9 | negative selection | 5020308 | 14294533 | 14294555 | 11 | - | 27760321 | HT29 | viability after 22 days | AGACAGATTCTCAGAGTAAAGG | RRAS2 | ENSG00000133818 | -0.9570037552622068 | [74,58] | [19,90,8] | -6 | hSpCas9 | negative selection | 5020309 | 14294847 | 14294869 | 11 | - | 27760321 | HT29 | viability after 22 days | CTTTAGTTTTGGATACAGCAGG | RRAS2 | ENSG00000133818 | -0.3649294837526367 | [185,144] | [58,248,139] | -4 | hSpCas9 | negative selection | 5020310 | 14295758 | 14295780 | 11 | + | 27760321 | HT29 | viability after 22 days | GTTTACTTACTATCTAGCCGGG | RRAS2 | ENSG00000133818 | -0.25962729274564755 | [114,89] | [72,92,131] | -3 | hSpCas9 | negative selection | 5020311 | 14281678 | 14281700 | 11 | - | 27760321 | HT29 | viability after 19 days | CAGTTAGCACGGCAGCTTAAGG | RRAS2 | ENSG00000133818 | 0.23572400351088987 | [457,357] | [428,455,742] | 2 | hSpCas9 | negative selection | 5103768 | 14281711 | 14281733 | 11 | - | 27760321 | HT29 | viability after 19 days | TTGGAATTTCAGGTAACACAGG | RRAS2 | ENSG00000133818 | -0.3120267671381951 | [70,55] | [19,24,123] | -3 | hSpCas9 | negative selection | 5103769 | 14294470 | 14294492 | 11 | - | 27760321 | HT29 | viability after 19 days | GATCTGGATCATCAAAGACAGG | RRAS2 | ENSG00000133818 | -0.21553315036351428 | [0,0] | [0,0,0] | -2 | hSpCas9 | negative selection | 5103770 | 14294497 | 14294519 | 11 | + | 27760321 | HT29 | viability after 19 days | TATTACCAATTAAAATCATTGG | RRAS2 | ENSG00000133818 | -0.21553315036351428 | [0,0] | [0,0,0] | -2 | hSpCas9 | negative selection | 5103771 | 14294533 | 14294555 | 11 | - | 27760321 | HT29 | viability after 19 days | AGACAGATTCTCAGAGTAAAGG | RRAS2 | ENSG00000133818 | -1.5117677718977443 | [74,58] | [40,37,3] | -7 | hSpCas9 | negative selection | 5103772 | 14294847 | 14294869 | 11 | - | 27760321 | HT29 | viability after 19 days | CTTTAGTTTTGGATACAGCAGG | RRAS2 | ENSG00000133818 | -0.7577642399650557 | [185,144] | [99,82,149] | -6 | hSpCas9 | negative selection | 5103773 | 14295758 | 14295780 | 11 | + | 27760321 | HT29 | viability after 19 days | GTTTACTTACTATCTAGCCGGG | RRAS2 | ENSG00000133818 | 0.14612375178152615 | [114,89] | [30,115,227] | 1 | hSpCas9 | negative selection | 5103774 | 14281678 | 14281700 | 11 | - | 27760321 | HT29 | viability after 16 days | CAGTTAGCACGGCAGCTTAAGG | RRAS2 | ENSG00000133818 | -0.07697988536214619 | [457,357] | [353,695,233] | -1 | hSpCas9 | negative selection | 5187231 | 14281711 | 14281733 | 11 | - | 27760321 | HT29 | viability after 16 days | TTGGAATTTCAGGTAACACAGG | RRAS2 | ENSG00000133818 | 0.8939970779444764 | [70,55] | [126,86,182] | 9 | hSpCas9 | negative selection | 5187232 | 14294470 | 14294492 | 11 | - | 27760321 | HT29 | viability after 16 days | GATCTGGATCATCAAAGACAGG | RRAS2 | ENSG00000133818 | -0.1840686979425925 | [0,0] | [0,0,0] | -2 | hSpCas9 | negative selection | 5187233 | 14294497 | 14294519 | 11 | + | 27760321 | HT29 | viability after 16 days | TATTACCAATTAAAATCATTGG | RRAS2 | ENSG00000133818 | -0.1840686979425925 | [0,0] | [0,0,0] | -2 | hSpCas9 | negative selection | 5187234 | 14294533 | 14294555 | 11 | - | 27760321 | HT29 | viability after 16 days | AGACAGATTCTCAGAGTAAAGG | RRAS2 | ENSG00000133818 | -0.3445011582577786 | [74,58] | [89,24,65] | -4 | hSpCas9 | negative selection | 5187235 | 14294847 | 14294869 | 11 | - | 27760321 | HT29 | viability after 16 days | CTTTAGTTTTGGATACAGCAGG | RRAS2 | ENSG00000133818 | -0.6131176869695656 | [185,144] | [139,155,67] | -5 | hSpCas9 | negative selection | 5187236 | 14295758 | 14295780 | 11 | + | 27760321 | HT29 | viability after 16 days | GTTTACTTACTATCTAGCCGGG | RRAS2 | ENSG00000133818 | -1.222341839923957 | [114,89] | [87,15,47] | -7 | hSpCas9 | negative selection | 5187237 | 14281678 | 14281700 | 11 | - | 27760321 | HT29 | viability after 13 days | CAGTTAGCACGGCAGCTTAAGG | RRAS2 | ENSG00000133818 | 0.13492044925893468 | [457,357] | [629,477,454] | 1 | hSpCas9 | negative selection | 5270694 | 14281711 | 14281733 | 11 | - | 27760321 | HT29 | viability after 13 days | TTGGAATTTCAGGTAACACAGG | RRAS2 | ENSG00000133818 | 0.4636572126858969 | [70,55] | [93,143,68] | 6 | hSpCas9 | negative selection | 5270695 | 14294470 | 14294492 | 11 | - | 27760321 | HT29 | viability after 13 days | GATCTGGATCATCAAAGACAGG | RRAS2 | ENSG00000133818 | -0.23635609738673047 | [0,0] | [0,0,0] | -3 | hSpCas9 | negative selection | 5270696 | 14294497 | 14294519 | 11 | + | 27760321 | HT29 | viability after 13 days | TATTACCAATTAAAATCATTGG | RRAS2 | ENSG00000133818 | -0.23635609738673047 | [0,0] | [0,0,0] | -3 | hSpCas9 | negative selection | 5270697 | 14294533 | 14294555 | 11 | - | 27760321 | HT29 | viability after 13 days | AGACAGATTCTCAGAGTAAAGG | RRAS2 | ENSG00000133818 | -0.717879741277839 | [74,58] | [9,85,45] | -6 | hSpCas9 | negative selection | 5270698 | 14294847 | 14294869 | 11 | - | 27760321 | HT29 | viability after 13 days | CTTTAGTTTTGGATACAGCAGG | RRAS2 | ENSG00000133818 | -0.3382399200754018 | [185,144] | [66,189,195] | -4 | hSpCas9 | negative selection | 5270699 | 14295758 | 14295780 | 11 | + | 27760321 | HT29 | viability after 13 days | GTTTACTTACTATCTAGCCGGG | RRAS2 | ENSG00000133818 | -1.434535860580971 | [114,89] | [40,46,43] | -8 | hSpCas9 | negative selection | 5270700 | 14281678 | 14281700 | 11 | - | 27760321 | HT29 | viability after 10 days | CAGTTAGCACGGCAGCTTAAGG | RRAS2 | ENSG00000133818 | -0.11853480954623254 | [457,357] | [547,358,496] | -1 | hSpCas9 | negative selection | 5354157 | 14281711 | 14281733 | 11 | - | 27760321 | HT29 | viability after 10 days | TTGGAATTTCAGGTAACACAGG | RRAS2 | ENSG00000133818 | 0.492820077257508 | [70,55] | [52,199,84] | 6 | hSpCas9 | negative selection | 5354158 | 14294470 | 14294492 | 11 | - | 27760321 | HT29 | viability after 10 days | GATCTGGATCATCAAAGACAGG | RRAS2 | ENSG00000133818 | -0.34236740454707437 | [0,0] | [0,0,0] | -4 | hSpCas9 | negative selection | 5354159 | 14294497 | 14294519 | 11 | + | 27760321 | HT29 | viability after 10 days | TATTACCAATTAAAATCATTGG | RRAS2 | ENSG00000133818 | -0.34236740454707437 | [0,0] | [0,0,0] | -4 | hSpCas9 | negative selection | 5354160 | 14294533 | 14294555 | 11 | - | 27760321 | HT29 | viability after 10 days | AGACAGATTCTCAGAGTAAAGG | RRAS2 | ENSG00000133818 | -0.301411784743403 | [74,58] | [25,71,104] | -4 | hSpCas9 | negative selection | 5354161 | 14294847 | 14294869 | 11 | - | 27760321 | HT29 | viability after 10 days | CTTTAGTTTTGGATACAGCAGG | RRAS2 | ENSG00000133818 | -0.04485652617195357 | [185,144] | [151,304,147] | 0 | hSpCas9 | negative selection | 5354162 | 14295758 | 14295780 | 11 | + | 27760321 | HT29 | viability after 10 days | GTTTACTTACTATCTAGCCGGG | RRAS2 | ENSG00000133818 | -0.9586361354135351 | [114,89] | [68,52,74] | -7 | hSpCas9 | negative selection | 5354163 | 14281678 | 14281700 | 11 | - | 27760321 | MOLM13 | viability | CAGTTAGCACGGCAGCTTAAGG | RRAS2 | ENSG00000133818 | 0.6128308984798366 | [487,457] | [604,240] | 4 | hSpCas9 | negative selection | 5437620 | 14281711 | 14281733 | 11 | - | 27760321 | MOLM13 | viability | TTGGAATTTCAGGTAACACAGG | RRAS2 | ENSG00000133818 | -0.7184001180330397 | [79,70] | [0,46] | -4 | hSpCas9 | negative selection | 5437621 | 14294470 | 14294492 | 11 | - | 27760321 | MOLM13 | viability | GATCTGGATCATCAAAGACAGG | RRAS2 | ENSG00000133818 | 0.8210053139495912 | [0,0] | [0,0] | 6 | hSpCas9 | negative selection | 5437622 | 14294497 | 14294519 | 11 | + | 27760321 | MOLM13 | viability | TATTACCAATTAAAATCATTGG | RRAS2 | ENSG00000133818 | 0.8210053139495912 | [0,0] | [0,0] | 6 | hSpCas9 | negative selection | 5437623 | 14294533 | 14294555 | 11 | - | 27760321 | MOLM13 | viability | AGACAGATTCTCAGAGTAAAGG | RRAS2 | ENSG00000133818 | -1.8003945599098072 | [134,74] | [0,29] | -7 | hSpCas9 | negative selection | 5437624 | 14294847 | 14294869 | 11 | - | 27760321 | MOLM13 | viability | CTTTAGTTTTGGATACAGCAGG | RRAS2 | ENSG00000133818 | 0.14279566251002151 | [193,185] | [70,158] | 1 | hSpCas9 | negative selection | 5437625 | 14295758 | 14295780 | 11 | + | 27760321 | MOLM13 | viability | GTTTACTTACTATCTAGCCGGG | RRAS2 | ENSG00000133818 | 0.2886818142558154 | [141,114] | [133,48] | 2 | hSpCas9 | negative selection | 5437626 | 14359068 | 14359091 | 11 | + | 27661255 | K562 | viability | GAGAAGCGGGGTGACGGCACGGG | RRAS2 | ENSG00000133818 | 0.05597284088481047 | [905,1029] | [815,789] | 2 | dCas9-KRAB | negative selection | 5508719 | 14358455 | 14358478 | 11 | - | 27661255 | K562 | viability | GGCCGAGGCCAGAGACCTCCGGG | RRAS2 | ENSG00000133818 | 0.014428035530367811 | [642,658] | [605,455] | 0 | dCas9-KRAB | negative selection | 5508720 | 14358823 | 14358846 | 11 | - | 27661255 | K562 | viability | GCTCCGGCCAGGAGAAGTACCGG | RRAS2 | ENSG00000133818 | 0.0827075799693926 | [248,210] | [199,190] | 3 | dCas9-KRAB | negative selection | 5508721 | 14359121 | 14359144 | 11 | - | 27661255 | K562 | viability | GGCGCTGCGGAGACGCGTAGAGG | RRAS2 | ENSG00000133818 | 0.03272337706447061 | [732,898] | [686,644] | 1 | dCas9-KRAB | negative selection | 5508722 | 14359134 | 14359157 | 11 | - | 27661255 | K562 | viability | GCTGCGTTCGGCAGGCGCTGCGG | RRAS2 | ENSG00000133818 | 0.3046025520400728 | [515,628] | [578,548] | 8 | dCas9-KRAB | negative selection | 5508723 | 14359146 | 14359169 | 11 | - | 27661255 | K562 | viability | GCGGCGCTGGAGGCTGCGTTCGG | RRAS2 | ENSG00000133818 | 0.22047883015649128 | [632,746] | [656,625] | 7 | dCas9-KRAB | negative selection | 5508724 | 14358804 | 14358827 | 11 | + | 27260156 | BXPC3 | viability | CCCCGCCGACCACCACGAGCCGG | RRAS2 | ENSG00000133818 | -0.053960360463041424 | [140] | [120,141,104,208] | -1 | hSpCas9 | negative selection | 5568329 | 14358857 | 14358880 | 11 | - | 27260156 | BXPC3 | viability | AGCGTCCCCATGGCCGCGGCCGG | RRAS2 | ENSG00000133818 | 0.4499208513332434 | [279] | [308,357,485,465] | 8 | hSpCas9 | negative selection | 5568330 | 14295757 | 14295780 | 11 | + | 27260156 | BXPC3 | viability | AGTTTACTTACTATCTAGCCGGG | RRAS2 | ENSG00000133818 | 0.0076009725348111234 | [399] | [317,454,390,537] | 0 | hSpCas9 | negative selection | 5568331 | 14295805 | 14295828 | 11 | + | 27260156 | BXPC3 | viability | CTTTGTGTAAGAATCTTCAATGG | RRAS2 | ENSG00000133818 | -0.596274500549689 | [107] | [31,64,120,87] | -8 | hSpCas9 | negative selection | 5632583 | 14294807 | 14294830 | 11 | - | 27260156 | BXPC3 | viability | CCATGAGAGAACAGTATATGAGG | RRAS2 | ENSG00000133818 | -0.10281684086820841 | [204] | [230,141,186,241] | -2 | hSpCas9 | negative selection | 5632584 | 14358804 | 14358827 | 11 | + | 27260156 | A673 | viability | CCCCGCCGACCACCACGAGCCGG | RRAS2 | ENSG00000133818 | -0.04648323719080172 | [140] | [148,184,172,144] | -1 | hSpCas9 | negative selection | 5689580 | 14358857 | 14358880 | 11 | - | 27260156 | A673 | viability | AGCGTCCCCATGGCCGCGGCCGG | RRAS2 | ENSG00000133818 | 0.5089417731169802 | [279] | [543,389,499,488] | 9 | hSpCas9 | negative selection | 5689581 | 14295757 | 14295780 | 11 | + | 27260156 | A673 | viability | AGTTTACTTACTATCTAGCCGGG | RRAS2 | ENSG00000133818 | -0.2284626211939684 | [399] | [533,381,266,475] | -5 | hSpCas9 | negative selection | 5689582 | 14295805 | 14295828 | 11 | + | 27260156 | A673 | viability | CTTTGTGTAAGAATCTTCAATGG | RRAS2 | ENSG00000133818 | -0.047678000919116226 | [107] | [160,122,96,124] | -1 | hSpCas9 | negative selection | 5753834 | 14294807 | 14294830 | 11 | - | 27260156 | A673 | viability | CCATGAGAGAACAGTATATGAGG | RRAS2 | ENSG00000133818 | -0.006737328023703304 | [204] | [233,244,241,257] | 0 | hSpCas9 | negative selection | 5753835 | 14358804 | 14358827 | 11 | + | 27260156 | A375 | viability | CCCCGCCGACCACCACGAGCCGG | RRAS2 | ENSG00000133818 | -0.12022689996202107 | [140] | [148,136,207,113] | -2 | hSpCas9 | negative selection | 5810831 | 14358857 | 14358880 | 11 | - | 27260156 | A375 | viability | AGCGTCCCCATGGCCGCGGCCGG | RRAS2 | ENSG00000133818 | 0.2683618740642347 | [279] | [399,437,373,370] | 4 | hSpCas9 | negative selection | 5810832 | 14295757 | 14295780 | 11 | + | 27260156 | A375 | viability | AGTTTACTTACTATCTAGCCGGG | RRAS2 | ENSG00000133818 | 0.2517030929632934 | [399] | [623,507,531,552] | 3 | hSpCas9 | negative selection | 5810833 | 14295805 | 14295828 | 11 | + | 27260156 | A375 | viability | CTTTGTGTAAGAATCTTCAATGG | RRAS2 | ENSG00000133818 | -0.3860841373728068 | [107] | [140,164,33,59] | -5 | hSpCas9 | negative selection | 5875085 | 14294807 | 14294830 | 11 | - | 27260156 | A375 | viability | CCATGAGAGAACAGTATATGAGG | RRAS2 | ENSG00000133818 | -0.037656331693642464 | [204] | [181,158,268,302] | 0 | hSpCas9 | negative selection | 5875086 | 14358804 | 14358827 | 11 | + | 27260156 | COLO741 | viability | CCCCGCCGACCACCACGAGCCGG | RRAS2 | ENSG00000133818 | -0.17132628902742453 | [140] | [164,140,172] | -4 | hSpCas9 | negative selection | 5932082 | 14358857 | 14358880 | 11 | - | 27260156 | COLO741 | viability | AGCGTCCCCATGGCCGCGGCCGG | RRAS2 | ENSG00000133818 | 0.4796492409992823 | [279] | [702,458,360] | 8 | hSpCas9 | negative selection | 5932083 | 14295757 | 14295780 | 11 | + | 27260156 | COLO741 | viability | AGTTTACTTACTATCTAGCCGGG | RRAS2 | ENSG00000133818 | -0.41313300513334483 | [399] | [338,355,446] | -7 | hSpCas9 | negative selection | 5932084 | 14295805 | 14295828 | 11 | + | 27260156 | COLO741 | viability | CTTTGTGTAAGAATCTTCAATGG | RRAS2 | ENSG00000133818 | 0.22695792334693432 | [107] | [157,249,81] | 5 | hSpCas9 | negative selection | 5996336 | 14294807 | 14294830 | 11 | - | 27260156 | COLO741 | viability | CCATGAGAGAACAGTATATGAGG | RRAS2 | ENSG00000133818 | -0.0694568727788285 | [204] | [231,364,156] | -1 | hSpCas9 | negative selection | 5996337 | 14358804 | 14358827 | 11 | + | 27260156 | CAL120 | viability | CCCCGCCGACCACCACGAGCCGG | RRAS2 | ENSG00000133818 | -0.7529938230973812 | [140] | [62,132,109] | -8 | hSpCas9 | negative selection | 6053333 | 14358857 | 14358880 | 11 | - | 27260156 | CAL120 | viability | AGCGTCCCCATGGCCGCGGCCGG | RRAS2 | ENSG00000133818 | 0.7484604385581732 | [279] | [512,369,856] | 9 | hSpCas9 | negative selection | 6053334 | 14295757 | 14295780 | 11 | + | 27260156 | CAL120 | viability | AGTTTACTTACTATCTAGCCGGG | RRAS2 | ENSG00000133818 | 0.26755882449340146 | [399] | [790,538,497] | 4 | hSpCas9 | negative selection | 6053335 | 14295805 | 14295828 | 11 | + | 27260156 | CAL120 | viability | CTTTGTGTAAGAATCTTCAATGG | RRAS2 | ENSG00000133818 | -1.0174603392998578 | [107] | [124,18,63] | -8 | hSpCas9 | negative selection | 6117587 | 14294807 | 14294830 | 11 | - | 27260156 | CAL120 | viability | CCATGAGAGAACAGTATATGAGG | RRAS2 | ENSG00000133818 | -0.5592150182375693 | [204] | [192,250,79] | -7 | hSpCas9 | negative selection | 6117588 | 14358804 | 14358827 | 11 | + | 27260156 | CADOES1 | viability | CCCCGCCGACCACCACGAGCCGG | RRAS2 | ENSG00000133818 | -0.0703922562085113 | [140] | [165,71,170,88] | -1 | hSpCas9 | negative selection | 6174584 | 14358857 | 14358880 | 11 | - | 27260156 | CADOES1 | viability | AGCGTCCCCATGGCCGCGGCCGG | RRAS2 | ENSG00000133818 | 0.5058676264884562 | [279] | [329,329,401,418] | 8 | hSpCas9 | negative selection | 6174585 | 14295757 | 14295780 | 11 | + | 27260156 | CADOES1 | viability | AGTTTACTTACTATCTAGCCGGG | RRAS2 | ENSG00000133818 | 0.04134114576678863 | [399] | [384,384,361,399] | 0 | hSpCas9 | negative selection | 6174586 | 14295805 | 14295828 | 11 | + | 27260156 | CADOES1 | viability | CTTTGTGTAAGAATCTTCAATGG | RRAS2 | ENSG00000133818 | -0.005173273870072048 | [107] | [68,74,139,116] | 0 | hSpCas9 | negative selection | 6238838 | 14294807 | 14294830 | 11 | - | 27260156 | CADOES1 | viability | CCATGAGAGAACAGTATATGAGG | RRAS2 | ENSG00000133818 | -0.7756878590478573 | [204] | [37,182,82,142] | -8 | hSpCas9 | negative selection | 6238839 | 14358804 | 14358827 | 11 | + | 27260156 | EWS502 | viability | CCCCGCCGACCACCACGAGCCGG | RRAS2 | ENSG00000133818 | -0.14591722481421265 | [140] | [78,103,178,189] | -3 | hSpCas9 | negative selection | 6295835 | 14358857 | 14358880 | 11 | - | 27260156 | EWS502 | viability | AGCGTCCCCATGGCCGCGGCCGG | RRAS2 | ENSG00000133818 | 0.5822354238648898 | [279] | [457,461,493,351] | 8 | hSpCas9 | negative selection | 6295836 | 14295757 | 14295780 | 11 | + | 27260156 | EWS502 | viability | AGTTTACTTACTATCTAGCCGGG | RRAS2 | ENSG00000133818 | 0.17049521788692262 | [399] | [527,404,433,538] | 3 | hSpCas9 | negative selection | 6295837 | 14295805 | 14295828 | 11 | + | 27260156 | EWS502 | viability | CTTTGTGTAAGAATCTTCAATGG | RRAS2 | ENSG00000133818 | 0.10645903864777528 | [107] | [127,58,168,139] | 1 | hSpCas9 | negative selection | 6360089 | 14294807 | 14294830 | 11 | - | 27260156 | EWS502 | viability | CCATGAGAGAACAGTATATGAGG | RRAS2 | ENSG00000133818 | -0.17451111546898224 | [204] | [248,178,121,212] | -3 | hSpCas9 | negative selection | 6360090 | 14358804 | 14358827 | 11 | + | 27260156 | EW8 | viability | CCCCGCCGACCACCACGAGCCGG | RRAS2 | ENSG00000133818 | -0.5954153464231664 | [140] | [121,14,63,107] | -8 | hSpCas9 | negative selection | 6417086 | 14358857 | 14358880 | 11 | - | 27260156 | EW8 | viability | AGCGTCCCCATGGCCGCGGCCGG | RRAS2 | ENSG00000133818 | 0.36162809989781225 | [279] | [315,260,284,306] | 6 | hSpCas9 | negative selection | 6417087 | 14295757 | 14295780 | 11 | + | 27260156 | EW8 | viability | AGTTTACTTACTATCTAGCCGGG | RRAS2 | ENSG00000133818 | 0.32649928361450925 | [399] | [620,459,330,249] | 6 | hSpCas9 | negative selection | 6417088 | 14295805 | 14295828 | 11 | + | 27260156 | EW8 | viability | CTTTGTGTAAGAATCTTCAATGG | RRAS2 | ENSG00000133818 | -0.5632938284989755 | [107] | [86,67,16,74] | -8 | hSpCas9 | negative selection | 6481340 | 14294807 | 14294830 | 11 | - | 27260156 | EW8 | viability | CCATGAGAGAACAGTATATGAGG | RRAS2 | ENSG00000133818 | -0.36084859458561014 | [204] | [165,111,93,154] | -6 | hSpCas9 | negative selection | 6481341 | 14358804 | 14358827 | 11 | + | 27260156 | CORL105 | viability | CCCCGCCGACCACCACGAGCCGG | RRAS2 | ENSG00000133818 | -0.39203260394998707 | [140] | [173,130,113,83] | -6 | hSpCas9 | negative selection | 6538337 | 14358857 | 14358880 | 11 | - | 27260156 | CORL105 | viability | AGCGTCCCCATGGCCGCGGCCGG | RRAS2 | ENSG00000133818 | 0.34117828652672577 | [279] | [388,490,479,308] | 6 | hSpCas9 | negative selection | 6538338 | 14295757 | 14295780 | 11 | + | 27260156 | CORL105 | viability | AGTTTACTTACTATCTAGCCGGG | RRAS2 | ENSG00000133818 | 0.3531839858017519 | [399] | [496,519,705,683] | 6 | hSpCas9 | negative selection | 6538339 | 14295805 | 14295828 | 11 | + | 27260156 | CORL105 | viability | CTTTGTGTAAGAATCTTCAATGG | RRAS2 | ENSG00000133818 | -0.9895504295276369 | [107] | [72,48,61,70] | -9 | hSpCas9 | negative selection | 6602591 | 14294807 | 14294830 | 11 | - | 27260156 | CORL105 | viability | CCATGAGAGAACAGTATATGAGG | RRAS2 | ENSG00000133818 | -0.2424222987067055 | [204] | [180,206,205,216] | -4 | hSpCas9 | negative selection | 6602592 | 14358804 | 14358827 | 11 | + | 27260156 | HS294T | viability | CCCCGCCGACCACCACGAGCCGG | RRAS2 | ENSG00000133818 | 0.2562221740101305 | [140] | [26,38,42,173] | 3 | hSpCas9 | negative selection | 6659588 | 14358857 | 14358880 | 11 | - | 27260156 | HS294T | viability | AGCGTCCCCATGGCCGCGGCCGG | RRAS2 | ENSG00000133818 | 0.23236781734915601 | [279] | [155,125,113,105] | 3 | hSpCas9 | negative selection | 6659589 | 14295757 | 14295780 | 11 | + | 27260156 | HS294T | viability | AGTTTACTTACTATCTAGCCGGG | RRAS2 | ENSG00000133818 | 0.22743804370918458 | [399] | [151,262,165,134] | 3 | hSpCas9 | negative selection | 6659590 | 14295805 | 14295828 | 11 | + | 27260156 | HS294T | viability | CTTTGTGTAAGAATCTTCAATGG | RRAS2 | ENSG00000133818 | -0.14826464154844698 | [107] | [32,59,20,35] | -2 | hSpCas9 | negative selection | 6723842 | 14294807 | 14294830 | 11 | - | 27260156 | HS294T | viability | CCATGAGAGAACAGTATATGAGG | RRAS2 | ENSG00000133818 | -0.5513633143604331 | [204] | [28,56,65,68] | -7 | hSpCas9 | negative selection | 6723843 | 14358804 | 14358827 | 11 | + | 27260156 | HCC44 | viability | CCCCGCCGACCACCACGAGCCGG | RRAS2 | ENSG00000133818 | -0.3596199023113298 | [140] | [120,111,113,147] | -5 | hSpCas9 | negative selection | 6780839 | 14358857 | 14358880 | 11 | - | 27260156 | HCC44 | viability | AGCGTCCCCATGGCCGCGGCCGG | RRAS2 | ENSG00000133818 | 0.6255082450959193 | [279] | [505,230,705,579] | 8 | hSpCas9 | negative selection | 6780840 | 14295757 | 14295780 | 11 | + | 27260156 | HCC44 | viability | AGTTTACTTACTATCTAGCCGGG | RRAS2 | ENSG00000133818 | 0.20319587488101568 | [399] | [828,378,488,427] | 3 | hSpCas9 | negative selection | 6780841 | 14295805 | 14295828 | 11 | + | 27260156 | HCC44 | viability | CTTTGTGTAAGAATCTTCAATGG | RRAS2 | ENSG00000133818 | -0.41292670262920783 | [107] | [185,29,110,60] | -6 | hSpCas9 | negative selection | 6845093 | 14294807 | 14294830 | 11 | - | 27260156 | HCC44 | viability | CCATGAGAGAACAGTATATGAGG | RRAS2 | ENSG00000133818 | -0.8728921476207983 | [204] | [95,116,122,165] | -8 | hSpCas9 | negative selection | 6845094 | 14358804 | 14358827 | 11 | + | 27260156 | G402 | viability | CCCCGCCGACCACCACGAGCCGG | RRAS2 | ENSG00000133818 | -0.5309783648373341 | [140] | [88,108,155,116] | -6 | hSpCas9 | negative selection | 6902090 | 14358857 | 14358880 | 11 | - | 27260156 | G402 | viability | AGCGTCCCCATGGCCGCGGCCGG | RRAS2 | ENSG00000133818 | 0.6662652392445316 | [279] | [317,329,868,601] | 7 | hSpCas9 | negative selection | 6902091 | 14295757 | 14295780 | 11 | + | 27260156 | G402 | viability | AGTTTACTTACTATCTAGCCGGG | RRAS2 | ENSG00000133818 | 0.271086037552471 | [399] | [784,610,605,390] | 3 | hSpCas9 | negative selection | 6902092 | 14295805 | 14295828 | 11 | + | 27260156 | G402 | viability | CTTTGTGTAAGAATCTTCAATGG | RRAS2 | ENSG00000133818 | -1.4310539994289684 | [107] | [115,14,64,8] | -9 | hSpCas9 | negative selection | 6966344 | 14294807 | 14294830 | 11 | - | 27260156 | G402 | viability | CCATGAGAGAACAGTATATGAGG | RRAS2 | ENSG00000133818 | -0.7230636277945142 | [204] | [88,65,145,283] | -7 | hSpCas9 | negative selection | 6966345 | 14358804 | 14358827 | 11 | + | 27260156 | L33 | viability | CCCCGCCGACCACCACGAGCCGG | RRAS2 | ENSG00000133818 | -0.018343456246566525 | [140] | [191,47,90,101] | 0 | hSpCas9 | negative selection | 7023341 | 14358857 | 14358880 | 11 | - | 27260156 | L33 | viability | AGCGTCCCCATGGCCGCGGCCGG | RRAS2 | ENSG00000133818 | -0.20531124686817737 | [279] | [226,141,125,197] | -5 | hSpCas9 | negative selection | 7023342 | 14295757 | 14295780 | 11 | + | 27260156 | L33 | viability | AGTTTACTTACTATCTAGCCGGG | RRAS2 | ENSG00000133818 | -0.2694357494673525 | [399] | [330,145,227,277] | -6 | hSpCas9 | negative selection | 7023343 | 14295805 | 14295828 | 11 | + | 27260156 | L33 | viability | CTTTGTGTAAGAATCTTCAATGG | RRAS2 | ENSG00000133818 | -0.3448548027268714 | [107] | [52,57,56,55] | -7 | hSpCas9 | negative selection | 7087595 | 14294807 | 14294830 | 11 | - | 27260156 | L33 | viability | CCATGAGAGAACAGTATATGAGG | RRAS2 | ENSG00000133818 | 0.026689784686728002 | [204] | [206,100,119,190] | 0 | hSpCas9 | negative selection | 7087596 | 14358804 | 14358827 | 11 | + | 27260156 | K562 | viability | CCCCGCCGACCACCACGAGCCGG | RRAS2 | ENSG00000133818 | 0.11944799055416455 | [140] | [96,190,44,201] | 1 | hSpCas9 | negative selection | 7144592 | 14358857 | 14358880 | 11 | - | 27260156 | K562 | viability | AGCGTCCCCATGGCCGCGGCCGG | RRAS2 | ENSG00000133818 | 0.9445183715449794 | [279] | [254,368,795,467] | 9 | hSpCas9 | negative selection | 7144593 | 14295757 | 14295780 | 11 | + | 27260156 | K562 | viability | AGTTTACTTACTATCTAGCCGGG | RRAS2 | ENSG00000133818 | 0.11713081088880731 | [399] | [631,321,147,445] | 1 | hSpCas9 | negative selection | 7144594 | 14295805 | 14295828 | 11 | + | 27260156 | K562 | viability | CTTTGTGTAAGAATCTTCAATGG | RRAS2 | ENSG00000133818 | 1.4644381982816628 | [107] | [169,782,72,72] | 9 | hSpCas9 | negative selection | 7208846 | 14294807 | 14294830 | 11 | - | 27260156 | K562 | viability | CCATGAGAGAACAGTATATGAGG | RRAS2 | ENSG00000133818 | -1.1514066164174157 | [204] | [54,38,129,96] | -8 | hSpCas9 | negative selection | 7208847 | 14358804 | 14358827 | 11 | + | 27260156 | HT29 | viability | CCCCGCCGACCACCACGAGCCGG | RRAS2 | ENSG00000133818 | -0.2604975453941454 | [140] | [125,158,175,113] | -5 | hSpCas9 | negative selection | 7265843 | 14358857 | 14358880 | 11 | - | 27260156 | HT29 | viability | AGCGTCCCCATGGCCGCGGCCGG | RRAS2 | ENSG00000133818 | 0.3134985617753318 | [279] | [422,522,494,274] | 6 | hSpCas9 | negative selection | 7265844 | 14295757 | 14295780 | 11 | + | 27260156 | HT29 | viability | AGTTTACTTACTATCTAGCCGGG | RRAS2 | ENSG00000133818 | 0.17889388262309835 | [399] | [543,541,707,418] | 3 | hSpCas9 | negative selection | 7265845 | 14295805 | 14295828 | 11 | + | 27260156 | HT29 | viability | CTTTGTGTAAGAATCTTCAATGG | RRAS2 | ENSG00000133818 | -0.2766794468827083 | [107] | [188,118,60,74] | -5 | hSpCas9 | negative selection | 7330097 | 14294807 | 14294830 | 11 | - | 27260156 | HT29 | viability | CCATGAGAGAACAGTATATGAGG | RRAS2 | ENSG00000133818 | -0.16768906662238536 | [204] | [329,237,172,161] | -3 | hSpCas9 | negative selection | 7330098 | 14358804 | 14358827 | 11 | + | 27260156 | MHHES1 | viability | CCCCGCCGACCACCACGAGCCGG | RRAS2 | ENSG00000133818 | -0.06400630808614527 | [140] | [97,273,82,153] | -1 | hSpCas9 | negative selection | 7387094 | 14358857 | 14358880 | 11 | - | 27260156 | MHHES1 | viability | AGCGTCCCCATGGCCGCGGCCGG | RRAS2 | ENSG00000133818 | -0.10397040049975637 | [279] | [321,412,185,266] | -2 | hSpCas9 | negative selection | 7387095 | 14295757 | 14295780 | 11 | + | 27260156 | MHHES1 | viability | AGTTTACTTACTATCTAGCCGGG | RRAS2 | ENSG00000133818 | 0.3493134144764251 | [399] | [776,517,490,525] | 6 | hSpCas9 | negative selection | 7387096 | 14295805 | 14295828 | 11 | + | 27260156 | MHHES1 | viability | CTTTGTGTAAGAATCTTCAATGG | RRAS2 | ENSG00000133818 | -0.47188050396284753 | [107] | [184,50,70,56] | -7 | hSpCas9 | negative selection | 7451348 | 14294807 | 14294830 | 11 | - | 27260156 | MHHES1 | viability | CCATGAGAGAACAGTATATGAGG | RRAS2 | ENSG00000133818 | -0.3074507034972791 | [204] | [244,112,188,192] | -5 | hSpCas9 | negative selection | 7451349 | 14358804 | 14358827 | 11 | + | 27260156 | MEWO | viability | CCCCGCCGACCACCACGAGCCGG | RRAS2 | ENSG00000133818 | -0.3390167157623962 | [140] | [144,48,126] | -6 | hSpCas9 | negative selection | 7508345 | 14358857 | 14358880 | 11 | - | 27260156 | MEWO | viability | AGCGTCCCCATGGCCGCGGCCGG | RRAS2 | ENSG00000133818 | 0.40625079397889513 | [279] | [430,271,354] | 8 | hSpCas9 | negative selection | 7508346 | 14295757 | 14295780 | 11 | + | 27260156 | MEWO | viability | AGTTTACTTACTATCTAGCCGGG | RRAS2 | ENSG00000133818 | 0.030721597086025537 | [399] | [386,313,446] | 0 | hSpCas9 | negative selection | 7508347 | 14295805 | 14295828 | 11 | + | 27260156 | MEWO | viability | CTTTGTGTAAGAATCTTCAATGG | RRAS2 | ENSG00000133818 | -0.757788021114556 | [107] | [103,23,59] | -9 | hSpCas9 | negative selection | 7572599 | 14294807 | 14294830 | 11 | - | 27260156 | MEWO | viability | CCATGAGAGAACAGTATATGAGG | RRAS2 | ENSG00000133818 | -0.7255429511027836 | [204] | [197,80,84] | -9 | hSpCas9 | negative selection | 7572600 | 14358804 | 14358827 | 11 | + | 27260156 | LNCAPCLONEFGC | viability | CCCCGCCGACCACCACGAGCCGG | RRAS2 | ENSG00000133818 | 0.009715709958008967 | [140] | [130,62,171,158] | 0 | hSpCas9 | negative selection | 7629596 | 14358857 | 14358880 | 11 | - | 27260156 | LNCAPCLONEFGC | viability | AGCGTCCCCATGGCCGCGGCCGG | RRAS2 | ENSG00000133818 | 0.5307527433534377 | [279] | [367,490,290,295] | 8 | hSpCas9 | negative selection | 7629597 | 14295757 | 14295780 | 11 | + | 27260156 | LNCAPCLONEFGC | viability | AGTTTACTTACTATCTAGCCGGG | RRAS2 | ENSG00000133818 | 0.17195152769926092 | [399] | [342,472,471,350] | 2 | hSpCas9 | negative selection | 7629598 | 14295805 | 14295828 | 11 | + | 27260156 | LNCAPCLONEFGC | viability | CTTTGTGTAAGAATCTTCAATGG | RRAS2 | ENSG00000133818 | -0.9960576636388385 | [107] | [54,37,63,41] | -8 | hSpCas9 | negative selection | 7693850 | 14294807 | 14294830 | 11 | - | 27260156 | LNCAPCLONEFGC | viability | CCATGAGAGAACAGTATATGAGG | RRAS2 | ENSG00000133818 | -0.4874254737033099 | [204] | [155,123,119,127] | -6 | hSpCas9 | negative selection | 7693851 | 14358804 | 14358827 | 11 | + | 27260156 | PANC0327 | viability | CCCCGCCGACCACCACGAGCCGG | RRAS2 | ENSG00000133818 | -0.6140458187157416 | [140] | [157,9,155,18] | -7 | hSpCas9 | negative selection | 7750847 | 14358857 | 14358880 | 11 | - | 27260156 | PANC0327 | viability | AGCGTCCCCATGGCCGCGGCCGG | RRAS2 | ENSG00000133818 | 0.9147923655156746 | [279] | [591,307,311,693] | 9 | hSpCas9 | negative selection | 7750848 | 14295757 | 14295780 | 11 | + | 27260156 | PANC0327 | viability | AGTTTACTTACTATCTAGCCGGG | RRAS2 | ENSG00000133818 | -0.013336299573526028 | [399] | [330,438,262,361] | 0 | hSpCas9 | negative selection | 7750849 | 14295805 | 14295828 | 11 | + | 27260156 | PANC0327 | viability | CTTTGTGTAAGAATCTTCAATGG | RRAS2 | ENSG00000133818 | -0.19817216241358926 | [107] | [182,79,21,57] | -3 | hSpCas9 | negative selection | 7815101 | 14294807 | 14294830 | 11 | - | 27260156 | PANC0327 | viability | CCATGAGAGAACAGTATATGAGG | RRAS2 | ENSG00000133818 | 0.25830474594617003 | [204] | [171,374,128,170] | 4 | hSpCas9 | negative selection | 7815102 | 14358804 | 14358827 | 11 | + | 27260156 | NCIH2009 | viability | CCCCGCCGACCACCACGAGCCGG | RRAS2 | ENSG00000133818 | 0.25599033718666675 | [140] | [330,194,198] | 3 | hSpCas9 | negative selection | 7872098 | 14358857 | 14358880 | 11 | - | 27260156 | NCIH2009 | viability | AGCGTCCCCATGGCCGCGGCCGG | RRAS2 | ENSG00000133818 | 0.4720512749514582 | [279] | [612,480,547] | 6 | hSpCas9 | negative selection | 7872099 | 14295757 | 14295780 | 11 | + | 27260156 | NCIH2009 | viability | AGTTTACTTACTATCTAGCCGGG | RRAS2 | ENSG00000133818 | -0.18920796141922822 | [399] | [596,478,414] | -3 | hSpCas9 | negative selection | 7872100 | 14295805 | 14295828 | 11 | + | 27260156 | NCIH2009 | viability | CTTTGTGTAAGAATCTTCAATGG | RRAS2 | ENSG00000133818 | -0.32397225095455884 | [107] | [173,64,133] | -4 | hSpCas9 | negative selection | 7936352 | 14294807 | 14294830 | 11 | - | 27260156 | NCIH2009 | viability | CCATGAGAGAACAGTATATGAGG | RRAS2 | ENSG00000133818 | -1.0630460125943058 | [204] | [147,146,117] | -8 | hSpCas9 | negative selection | 7936353 | 14358804 | 14358827 | 11 | + | 27260156 | NCIH1373 | viability | CCCCGCCGACCACCACGAGCCGG | RRAS2 | ENSG00000133818 | -0.19873131765814933 | [140] | [172,214,90,16] | -2 | hSpCas9 | negative selection | 7993349 | 14358857 | 14358880 | 11 | - | 27260156 | NCIH1373 | viability | AGCGTCCCCATGGCCGCGGCCGG | RRAS2 | ENSG00000133818 | 0.47157827430902605 | [279] | [758,292,397,91] | 4 | hSpCas9 | negative selection | 7993350 | 14295757 | 14295780 | 11 | + | 27260156 | NCIH1373 | viability | AGTTTACTTACTATCTAGCCGGG | RRAS2 | ENSG00000133818 | 0.5351226956541669 | [399] | [976,637,509,135] | 5 | hSpCas9 | negative selection | 7993351 | 14295805 | 14295828 | 11 | + | 27260156 | NCIH1373 | viability | CTTTGTGTAAGAATCTTCAATGG | RRAS2 | ENSG00000133818 | -0.5249230624738783 | [107] | [81,71,105,19] | -5 | hSpCas9 | negative selection | 8057603 | 14294807 | 14294830 | 11 | - | 27260156 | NCIH1373 | viability | CCATGAGAGAACAGTATATGAGG | RRAS2 | ENSG00000133818 | -0.9838283117068192 | [204] | [79,121,91,43] | -7 | hSpCas9 | negative selection | 8057604 | 14358804 | 14358827 | 11 | + | 27260156 | PATU8902 | viability | CCCCGCCGACCACCACGAGCCGG | RRAS2 | ENSG00000133818 | -0.7754705147375638 | [140] | [96,214,47,115] | -6 | hSpCas9 | negative selection | 8114600 | 14358857 | 14358880 | 11 | - | 27260156 | PATU8902 | viability | AGCGTCCCCATGGCCGCGGCCGG | RRAS2 | ENSG00000133818 | 0.651991285813246 | [279] | [333,690,670,755] | 7 | hSpCas9 | negative selection | 8114601 | 14295757 | 14295780 | 11 | + | 27260156 | PATU8902 | viability | AGTTTACTTACTATCTAGCCGGG | RRAS2 | ENSG00000133818 | 0.733644854864546 | [399] | [819,1164,555,1299] | 7 | hSpCas9 | negative selection | 8114602 | 14295805 | 14295828 | 11 | + | 27260156 | PATU8902 | viability | CTTTGTGTAAGAATCTTCAATGG | RRAS2 | ENSG00000133818 | -1.6405891536295591 | [107] | [41,102,6,51] | -8 | hSpCas9 | negative selection | 8178854 | 14294807 | 14294830 | 11 | - | 27260156 | PATU8902 | viability | CCATGAGAGAACAGTATATGAGG | RRAS2 | ENSG00000133818 | -0.1039140150476483 | [204] | [110,379,319,233] | -1 | hSpCas9 | negative selection | 8178855 | 14358804 | 14358827 | 11 | + | 27260156 | PANC1 | viability | CCCCGCCGACCACCACGAGCCGG | RRAS2 | ENSG00000133818 | -0.07548106800802135 | [140] | [57,88,156,144] | -1 | hSpCas9 | negative selection | 8235851 | 14358857 | 14358880 | 11 | - | 27260156 | PANC1 | viability | AGCGTCCCCATGGCCGCGGCCGG | RRAS2 | ENSG00000133818 | 0.5206714367874223 | [279] | [281,308,452,327] | 8 | hSpCas9 | negative selection | 8235852 | 14295757 | 14295780 | 11 | + | 27260156 | PANC1 | viability | AGTTTACTTACTATCTAGCCGGG | RRAS2 | ENSG00000133818 | 0.14907746816353848 | [399] | [393,508,334,315] | 2 | hSpCas9 | negative selection | 8235853 | 14295805 | 14295828 | 11 | + | 27260156 | PANC1 | viability | CTTTGTGTAAGAATCTTCAATGG | RRAS2 | ENSG00000133818 | -0.2511234024953506 | [107] | [48,91,133,44] | -4 | hSpCas9 | negative selection | 8300105 | 14294807 | 14294830 | 11 | - | 27260156 | PANC1 | viability | CCATGAGAGAACAGTATATGAGG | RRAS2 | ENSG00000133818 | -0.3938420009038439 | [204] | [103,166,94,168] | -6 | hSpCas9 | negative selection | 8300106 | 14358804 | 14358827 | 11 | + | 27260156 | PANC0813 | viability | CCCCGCCGACCACCACGAGCCGG | RRAS2 | ENSG00000133818 | -0.2935757658661473 | [140] | [119,90,120,202] | -5 | hSpCas9 | negative selection | 8357102 | 14358857 | 14358880 | 11 | - | 27260156 | PANC0813 | viability | AGCGTCCCCATGGCCGCGGCCGG | RRAS2 | ENSG00000133818 | 0.29340831074722734 | [279] | [492,373,285,462] | 5 | hSpCas9 | negative selection | 8357103 | 14295757 | 14295780 | 11 | + | 27260156 | PANC0813 | viability | AGTTTACTTACTATCTAGCCGGG | RRAS2 | ENSG00000133818 | -0.03703300290642278 | [399] | [501,305,659,372] | 0 | hSpCas9 | negative selection | 8357104 | 14295805 | 14295828 | 11 | + | 27260156 | PANC0813 | viability | CTTTGTGTAAGAATCTTCAATGG | RRAS2 | ENSG00000133818 | -0.4333291395730763 | [107] | [148,84,94,53] | -6 | hSpCas9 | negative selection | 8421356 | 14294807 | 14294830 | 11 | - | 27260156 | PANC0813 | viability | CCATGAGAGAACAGTATATGAGG | RRAS2 | ENSG00000133818 | 0.4675256838651649 | [204] | [382,332,205,408] | 7 | hSpCas9 | negative selection | 8421357 | 14358804 | 14358827 | 11 | + | 27260156 | RDES | viability | CCCCGCCGACCACCACGAGCCGG | RRAS2 | ENSG00000133818 | -0.21741787749033792 | [140] | [137,105,138,179] | -4 | hSpCas9 | negative selection | 8478353 | 14358857 | 14358880 | 11 | - | 27260156 | RDES | viability | AGCGTCCCCATGGCCGCGGCCGG | RRAS2 | ENSG00000133818 | 0.450200058760051 | [279] | [309,469,509,492] | 7 | hSpCas9 | negative selection | 8478354 | 14295757 | 14295780 | 11 | + | 27260156 | RDES | viability | AGTTTACTTACTATCTAGCCGGG | RRAS2 | ENSG00000133818 | 0.16927632597470932 | [399] | [464,448,594,572] | 2 | hSpCas9 | negative selection | 8478355 | 14295805 | 14295828 | 11 | + | 27260156 | RDES | viability | CTTTGTGTAAGAATCTTCAATGG | RRAS2 | ENSG00000133818 | -0.4696415363623103 | [107] | [72,70,114,105] | -7 | hSpCas9 | negative selection | 8542607 | 14294807 | 14294830 | 11 | - | 27260156 | RDES | viability | CCATGAGAGAACAGTATATGAGG | RRAS2 | ENSG00000133818 | -0.9818272055350195 | [204] | [105,112,94,169] | -9 | hSpCas9 | negative selection | 8542608 | 14358804 | 14358827 | 11 | + | 27260156 | PC3 | viability | CCCCGCCGACCACCACGAGCCGG | RRAS2 | ENSG00000133818 | -0.4244611014305455 | [140] | [99,61,169,101] | -7 | hSpCas9 | negative selection | 8599604 | 14358857 | 14358880 | 11 | - | 27260156 | PC3 | viability | AGCGTCCCCATGGCCGCGGCCGG | RRAS2 | ENSG00000133818 | 0.44865165844296856 | [279] | [327,369,589,286] | 8 | hSpCas9 | negative selection | 8599605 | 14295757 | 14295780 | 11 | + | 27260156 | PC3 | viability | AGTTTACTTACTATCTAGCCGGG | RRAS2 | ENSG00000133818 | -0.1307166761749615 | [399] | [279,330,653,297] | -3 | hSpCas9 | negative selection | 8599606 | 14295805 | 14295828 | 11 | + | 27260156 | PC3 | viability | CTTTGTGTAAGAATCTTCAATGG | RRAS2 | ENSG00000133818 | -0.27055086617942026 | [107] | [49,106,101,111] | -6 | hSpCas9 | negative selection | 8663858 | 14294807 | 14294830 | 11 | - | 27260156 | PC3 | viability | CCATGAGAGAACAGTATATGAGG | RRAS2 | ENSG00000133818 | 0.09251459328728107 | [204] | [143,179,268,314] | 2 | hSpCas9 | negative selection | 8663859 | 14358804 | 14358827 | 11 | + | 27260156 | PATU8988T | viability | CCCCGCCGACCACCACGAGCCGG | RRAS2 | ENSG00000133818 | -0.30184632148752644 | [140] | [54,144,143,99] | -5 | hSpCas9 | negative selection | 8720855 | 14358857 | 14358880 | 11 | - | 27260156 | PATU8988T | viability | AGCGTCCCCATGGCCGCGGCCGG | RRAS2 | ENSG00000133818 | 0.642979552788441 | [279] | [431,491,227,557] | 9 | hSpCas9 | negative selection | 8720856 | 14295757 | 14295780 | 11 | + | 27260156 | PATU8988T | viability | AGTTTACTTACTATCTAGCCGGG | RRAS2 | ENSG00000133818 | -0.24788921293591495 | [399] | [286,376,276,369] | -4 | hSpCas9 | negative selection | 8720857 | 14295805 | 14295828 | 11 | + | 27260156 | PATU8988T | viability | CTTTGTGTAAGAATCTTCAATGG | RRAS2 | ENSG00000133818 | 0.4312542294474222 | [107] | [104,137,139,182] | 7 | hSpCas9 | negative selection | 8785109 | 14294807 | 14294830 | 11 | - | 27260156 | PATU8988T | viability | CCATGAGAGAACAGTATATGAGG | RRAS2 | ENSG00000133818 | 0.1557460213368087 | [204] | [239,131,109,408] | 2 | hSpCas9 | negative selection | 8785110 | 14358804 | 14358827 | 11 | + | 27260156 | T47D | viability | CCCCGCCGACCACCACGAGCCGG | RRAS2 | ENSG00000133818 | 0.16635589896399972 | [140] | [213,151,131,244] | 3 | hSpCas9 | negative selection | 8842106 | 14358857 | 14358880 | 11 | - | 27260156 | T47D | viability | AGCGTCCCCATGGCCGCGGCCGG | RRAS2 | ENSG00000133818 | 0.44596345288231004 | [279] | [489,418,404,466] | 8 | hSpCas9 | negative selection | 8842107 | 14295757 | 14295780 | 11 | + | 27260156 | T47D | viability | AGTTTACTTACTATCTAGCCGGG | RRAS2 | ENSG00000133818 | -0.030088808591561017 | [399] | [451,418,477,479] | 0 | hSpCas9 | negative selection | 8842108 | 14295805 | 14295828 | 11 | + | 27260156 | T47D | viability | CTTTGTGTAAGAATCTTCAATGG | RRAS2 | ENSG00000133818 | -0.014397069942314822 | [107] | [141,89,103,166] | 0 | hSpCas9 | negative selection | 8906360 | 14294807 | 14294830 | 11 | - | 27260156 | T47D | viability | CCATGAGAGAACAGTATATGAGG | RRAS2 | ENSG00000133818 | -0.19948626187334995 | [204] | [194,211,242,179] | -4 | hSpCas9 | negative selection | 8906361 | 14358804 | 14358827 | 11 | + | 27260156 | SU8686 | viability | CCCCGCCGACCACCACGAGCCGG | RRAS2 | ENSG00000133818 | -0.07182303070180374 | [140] | [94,132,122,193] | -1 | hSpCas9 | negative selection | 8963357 | 14358857 | 14358880 | 11 | - | 27260156 | SU8686 | viability | AGCGTCCCCATGGCCGCGGCCGG | RRAS2 | ENSG00000133818 | -0.06612852028279559 | [279] | [161,286,300,328] | -1 | hSpCas9 | negative selection | 8963358 | 14295757 | 14295780 | 11 | + | 27260156 | SU8686 | viability | AGTTTACTTACTATCTAGCCGGG | RRAS2 | ENSG00000133818 | 0.3896408107698517 | [399] | [377,437,642,669] | 6 | hSpCas9 | negative selection | 8963359 | 14295805 | 14295828 | 11 | + | 27260156 | SU8686 | viability | CTTTGTGTAAGAATCTTCAATGG | RRAS2 | ENSG00000133818 | -1.0861006711975594 | [107] | [39,92,36,21] | -8 | hSpCas9 | negative selection | 9027611 | 14294807 | 14294830 | 11 | - | 27260156 | SU8686 | viability | CCATGAGAGAACAGTATATGAGG | RRAS2 | ENSG00000133818 | 0.059503653479332286 | [204] | [183,162,202,322] | 1 | hSpCas9 | negative selection | 9027612 | 14358804 | 14358827 | 11 | + | 27260156 | SKES1 | viability | CCCCGCCGACCACCACGAGCCGG | RRAS2 | ENSG00000133818 | 0.043196622734894774 | [140] | [233,166,105,92] | 1 | hSpCas9 | negative selection | 9084608 | 14358857 | 14358880 | 11 | - | 27260156 | SKES1 | viability | AGCGTCCCCATGGCCGCGGCCGG | RRAS2 | ENSG00000133818 | 0.5162794131696704 | [279] | [441,452,341,372] | 9 | hSpCas9 | negative selection | 9084609 | 14295757 | 14295780 | 11 | + | 27260156 | SKES1 | viability | AGTTTACTTACTATCTAGCCGGG | RRAS2 | ENSG00000133818 | 0.11222240091244542 | [399] | [530,433,360,411] | 2 | hSpCas9 | negative selection | 9084610 | 14295805 | 14295828 | 11 | + | 27260156 | SKES1 | viability | CTTTGTGTAAGAATCTTCAATGG | RRAS2 | ENSG00000133818 | -0.6949873837037535 | [107] | [51,66,73,69] | -9 | hSpCas9 | negative selection | 9148862 | 14294807 | 14294830 | 11 | - | 27260156 | SKES1 | viability | CCATGAGAGAACAGTATATGAGG | RRAS2 | ENSG00000133818 | -0.6346999822026704 | [204] | [155,141,95,135] | -8 | hSpCas9 | negative selection | 9148863 | 14358804 | 14358827 | 11 | + | 27260156 | TOV112D | viability | CCCCGCCGACCACCACGAGCCGG | RRAS2 | ENSG00000133818 | 0.37953215064073875 | [140] | [289,138,137,165] | 7 | hSpCas9 | negative selection | 9205859 | 14358857 | 14358880 | 11 | - | 27260156 | TOV112D | viability | AGCGTCCCCATGGCCGCGGCCGG | RRAS2 | ENSG00000133818 | 0.8941675638509435 | [279] | [441,776,464,457] | 9 | hSpCas9 | negative selection | 9205860 | 14295757 | 14295780 | 11 | + | 27260156 | TOV112D | viability | AGTTTACTTACTATCTAGCCGGG | RRAS2 | ENSG00000133818 | 0.14837576728197993 | [399] | [531,450,485,318] | 3 | hSpCas9 | negative selection | 9205861 | 14295805 | 14295828 | 11 | + | 27260156 | TOV112D | viability | CTTTGTGTAAGAATCTTCAATGG | RRAS2 | ENSG00000133818 | -1.410469466163693 | [107] | [24,72,54,16] | -9 | hSpCas9 | negative selection | 9270113 | 14294807 | 14294830 | 11 | - | 27260156 | TOV112D | viability | CCATGAGAGAACAGTATATGAGG | RRAS2 | ENSG00000133818 | -0.18394425022973193 | [204] | [356,216,84,89] | -4 | hSpCas9 | negative selection | 9270114 | 14358804 | 14358827 | 11 | + | 27260156 | TC71 | viability | CCCCGCCGACCACCACGAGCCGG | RRAS2 | ENSG00000133818 | 0.025897399459061887 | [140] | [110,187,144,173] | 0 | hSpCas9 | negative selection | 9327110 | 14358857 | 14358880 | 11 | - | 27260156 | TC71 | viability | AGCGTCCCCATGGCCGCGGCCGG | RRAS2 | ENSG00000133818 | 0.29534121612722797 | [279] | [343,318,404,406] | 7 | hSpCas9 | negative selection | 9327111 | 14295757 | 14295780 | 11 | + | 27260156 | TC71 | viability | AGTTTACTTACTATCTAGCCGGG | RRAS2 | ENSG00000133818 | -0.1783375690913506 | [399] | [428,394,369,316] | -5 | hSpCas9 | negative selection | 9327112 | 14295805 | 14295828 | 11 | + | 27260156 | TC71 | viability | CTTTGTGTAAGAATCTTCAATGG | RRAS2 | ENSG00000133818 | -0.35455095820209737 | [107] | [96,107,94,59] | -7 | hSpCas9 | negative selection | 9391364 | 14294807 | 14294830 | 11 | - | 27260156 | TC71 | viability | CCATGAGAGAACAGTATATGAGG | RRAS2 | ENSG00000133818 | -0.0467509088724436 | [204] | [209,219,189,232] | -1 | hSpCas9 | negative selection | 9391365 | 14358804 | 14358827 | 11 | + | 27260156 | TC32 | viability | CCCCGCCGACCACCACGAGCCGG | RRAS2 | ENSG00000133818 | 0.17129339958707868 | [140] | [120,81,173,250] | 3 | hSpCas9 | negative selection | 9448361 | 14358857 | 14358880 | 11 | - | 27260156 | TC32 | viability | AGCGTCCCCATGGCCGCGGCCGG | RRAS2 | ENSG00000133818 | 0.4707003284113225 | [279] | [324,324,434,383] | 7 | hSpCas9 | negative selection | 9448362 | 14295757 | 14295780 | 11 | + | 27260156 | TC32 | viability | AGTTTACTTACTATCTAGCCGGG | RRAS2 | ENSG00000133818 | 0.2989367093268442 | [399] | [438,377,670,400] | 5 | hSpCas9 | negative selection | 9448363 | 14295805 | 14295828 | 11 | + | 27260156 | TC32 | viability | CTTTGTGTAAGAATCTTCAATGG | RRAS2 | ENSG00000133818 | 0.041691651524767614 | [107] | [62,101,133,124] | 0 | hSpCas9 | negative selection | 9512615 | 14294807 | 14294830 | 11 | - | 27260156 | TC32 | viability | CCATGAGAGAACAGTATATGAGG | RRAS2 | ENSG00000133818 | 0.007320170328527054 | [204] | [133,220,250,160] | 0 | hSpCas9 | negative selection | 9512616 | 14281688 | 14281711 | 11 | - | 28162770 | P31FUJ | viability | AAGAAGGACAACAGTTAGCACGG | RRAS2 | ENSG00000133818 | 0.5179872284893781 | [456] | [768] | 6 | hSpCas9 | negative selection | 10228322 | 14294785 | 14294808 | 11 | - | 28162770 | P31FUJ | viability | GACTGGCGAAGGCTTCCTGTTGG | RRAS2 | ENSG00000133818 | -1.9401613364952615 | [208] | [63] | -8 | hSpCas9 | negative selection | 10228323 | 14281711 | 14281734 | 11 | - | 28162770 | P31FUJ | viability | GTTGGAATTTCAGGTAACACAGG | RRAS2 | ENSG00000133818 | 0.14405210097657717 | [401] | [521] | 1 | hSpCas9 | negative selection | 10228324 | 14281678 | 14281701 | 11 | - | 28162770 | P31FUJ | viability | ACAGTTAGCACGGCAGCTTAAGG | RRAS2 | ENSG00000133818 | 0.4622576627160606 | [495] | [802] | 5 | hSpCas9 | negative selection | 10228325 | 14294832 | 14294855 | 11 | - | 28162770 | P31FUJ | viability | ACAGCAGGACAAGAAGAGTTTGG | RRAS2 | ENSG00000133818 | -0.025477231166872505 | [109] | [126] | 0 | hSpCas9 | negative selection | 10228326 | 14358813 | 14358836 | 11 | - | 28162770 | P31FUJ | viability | GGAGAAGTACCGGCTCGTGGTGG | RRAS2 | ENSG00000133818 | 0.1668052542948592 | [140] | [185] | 1 | hSpCas9 | negative selection | 10228327 | 14358861 | 14358884 | 11 | - | 28162770 | P31FUJ | viability | CTGTAGCGTCCCCATGGCCGCGG | RRAS2 | ENSG00000133818 | 0.16755871823202106 | [493] | [651] | 1 | hSpCas9 | negative selection | 10228328 | 14358823 | 14358846 | 11 | - | 28162770 | P31FUJ | viability | GCTCCGGCCAGGAGAAGTACCGG | RRAS2 | ENSG00000133818 | 0.7801756495838315 | [331] | [669] | 8 | hSpCas9 | negative selection | 10228329 | 14358757 | 14358780 | 11 | + | 28162770 | P31FUJ | viability | AGGTACCTGGATGAACTGGATGG | RRAS2 | ENSG00000133818 | 0.03525901849424798 | [190] | [229] | 0 | hSpCas9 | negative selection | 10228330 | 14281663 | 14281686 | 11 | - | 28162770 | P31FUJ | viability | GCTTAAGGTAACATACATGGAGG | RRAS2 | ENSG00000133818 | -0.296932541834094 | [45] | [43] | -3 | hSpCas9 | negative selection | 10228331 | 14281688 | 14281711 | 11 | - | 28162770 | TF1 | viability | AAGAAGGACAACAGTTAGCACGG | RRAS2 | ENSG00000133818 | NaN | [NaN] | [293] | 1 | hSpCas9 | negative selection | 10397688 | 14294785 | 14294808 | 11 | - | 28162770 | TF1 | viability | GACTGGCGAAGGCTTCCTGTTGG | RRAS2 | ENSG00000133818 | NaN | [NaN] | [11] | 1 | hSpCas9 | negative selection | 10397689 | 14281711 | 14281734 | 11 | - | 28162770 | TF1 | viability | GTTGGAATTTCAGGTAACACAGG | RRAS2 | ENSG00000133818 | NaN | [NaN] | [399] | 1 | hSpCas9 | negative selection | 10397690 | 14281678 | 14281701 | 11 | - | 28162770 | TF1 | viability | ACAGTTAGCACGGCAGCTTAAGG | RRAS2 | ENSG00000133818 | NaN | [NaN] | [740] | 1 | hSpCas9 | negative selection | 10397691 | 14294832 | 14294855 | 11 | - | 28162770 | TF1 | viability | ACAGCAGGACAAGAAGAGTTTGG | RRAS2 | ENSG00000133818 | NaN | [NaN] | [37] | 1 | hSpCas9 | negative selection | 10397692 | 14358813 | 14358836 | 11 | - | 28162770 | TF1 | viability | GGAGAAGTACCGGCTCGTGGTGG | RRAS2 | ENSG00000133818 | NaN | [NaN] | [199] | 1 | hSpCas9 | negative selection | 10397693 | 14358861 | 14358884 | 11 | - | 28162770 | TF1 | viability | CTGTAGCGTCCCCATGGCCGCGG | RRAS2 | ENSG00000133818 | NaN | [NaN] | [330] | 1 | hSpCas9 | negative selection | 10397694 | 14358823 | 14358846 | 11 | - | 28162770 | TF1 | viability | GCTCCGGCCAGGAGAAGTACCGG | RRAS2 | ENSG00000133818 | NaN | [NaN] | [532] | 1 | hSpCas9 | negative selection | 10397695 | 14358757 | 14358780 | 11 | + | 28162770 | TF1 | viability | AGGTACCTGGATGAACTGGATGG | RRAS2 | ENSG00000133818 | NaN | [NaN] | [163] | 1 | hSpCas9 | negative selection | 10397696 | 14281663 | 14281686 | 11 | - | 28162770 | TF1 | viability | GCTTAAGGTAACATACATGGAGG | RRAS2 | ENSG00000133818 | NaN | [NaN] | [0] | 1 | hSpCas9 | negative selection | 10397697 | 14281688 | 14281711 | 11 | - | 28162770 | SKM1 | viability | AAGAAGGACAACAGTTAGCACGG | RRAS2 | ENSG00000133818 | 0.14885195631847803 | [149] | [293] | 1 | hSpCas9 | negative selection | 10567054 | 14294785 | 14294808 | 11 | - | 28162770 | SKM1 | viability | GACTGGCGAAGGCTTCCTGTTGG | RRAS2 | ENSG00000133818 | -1.9812002928712593 | [66] | [29] | -8 | hSpCas9 | negative selection | 10567055 | 14281711 | 14281734 | 11 | - | 28162770 | SKM1 | viability | GTTGGAATTTCAGGTAACACAGG | RRAS2 | ENSG00000133818 | 0.1714849950193199 | [110] | [220] | 1 | hSpCas9 | negative selection | 10567056 | 14281678 | 14281701 | 11 | - | 28162770 | SKM1 | viability | ACAGTTAGCACGGCAGCTTAAGG | RRAS2 | ENSG00000133818 | 0.6997669762119567 | [139] | [401] | 6 | hSpCas9 | negative selection | 10567057 | 14294832 | 14294855 | 11 | - | 28162770 | SKM1 | viability | ACAGCAGGACAAGAAGAGTTTGG | RRAS2 | ENSG00000133818 | 0.10644504095296037 | [30] | [58] | 1 | hSpCas9 | negative selection | 10567058 | 14358813 | 14358836 | 11 | - | 28162770 | SKM1 | viability | GGAGAAGTACCGGCTCGTGGTGG | RRAS2 | ENSG00000133818 | 0.7629608026991507 | [34] | [104] | 7 | hSpCas9 | negative selection | 10567059 | 14358861 | 14358884 | 11 | - | 28162770 | SKM1 | viability | CTGTAGCGTCCCCATGGCCGCGG | RRAS2 | ENSG00000133818 | 0.3982644222060545 | [96] | [225] | 4 | hSpCas9 | negative selection | 10567060 | 14358823 | 14358846 | 11 | - | 28162770 | SKM1 | viability | GCTCCGGCCAGGAGAAGTACCGG | RRAS2 | ENSG00000133818 | 0.7865155306780474 | [80] | [246] | 7 | hSpCas9 | negative selection | 10567061 | 14358757 | 14358780 | 11 | + | 28162770 | SKM1 | viability | AGGTACCTGGATGAACTGGATGG | RRAS2 | ENSG00000133818 | 0.56756511374072 | [49] | [130] | 5 | hSpCas9 | negative selection | 10567062 | 14281663 | 14281686 | 11 | - | 28162770 | SKM1 | viability | GCTTAAGGTAACATACATGGAGG | RRAS2 | ENSG00000133818 | -3.237039197300849 | [15] | [2] | -9 | hSpCas9 | negative selection | 10567063 | 14281688 | 14281711 | 11 | - | 28162770 | SKM1 | viability | AAGAAGGACAACAGTTAGCACGG | RRAS2 | ENSG00000133818 | 0.14885195631847803 | [149] | [293] | 1 | hSpCas9 | negative selection | 10736420 | 14294785 | 14294808 | 11 | - | 28162770 | SKM1 | viability | GACTGGCGAAGGCTTCCTGTTGG | RRAS2 | ENSG00000133818 | -1.9812002928712593 | [66] | [29] | -8 | hSpCas9 | negative selection | 10736421 | 14281711 | 14281734 | 11 | - | 28162770 | SKM1 | viability | GTTGGAATTTCAGGTAACACAGG | RRAS2 | ENSG00000133818 | 0.1714849950193199 | [110] | [220] | 1 | hSpCas9 | negative selection | 10736422 | 14281678 | 14281701 | 11 | - | 28162770 | SKM1 | viability | ACAGTTAGCACGGCAGCTTAAGG | RRAS2 | ENSG00000133818 | 0.6997669762119567 | [139] | [401] | 6 | hSpCas9 | negative selection | 10736423 | 14294832 | 14294855 | 11 | - | 28162770 | SKM1 | viability | ACAGCAGGACAAGAAGAGTTTGG | RRAS2 | ENSG00000133818 | 0.10644504095296037 | [30] | [58] | 1 | hSpCas9 | negative selection | 10736424 | 14358813 | 14358836 | 11 | - | 28162770 | SKM1 | viability | GGAGAAGTACCGGCTCGTGGTGG | RRAS2 | ENSG00000133818 | 0.7629608026991507 | [34] | [104] | 7 | hSpCas9 | negative selection | 10736425 | 14358861 | 14358884 | 11 | - | 28162770 | SKM1 | viability | CTGTAGCGTCCCCATGGCCGCGG | RRAS2 | ENSG00000133818 | 0.3982644222060545 | [96] | [225] | 4 | hSpCas9 | negative selection | 10736426 | 14358823 | 14358846 | 11 | - | 28162770 | SKM1 | viability | GCTCCGGCCAGGAGAAGTACCGG | RRAS2 | ENSG00000133818 | 0.7865155306780474 | [80] | [246] | 7 | hSpCas9 | negative selection | 10736427 | 14358757 | 14358780 | 11 | + | 28162770 | SKM1 | viability | AGGTACCTGGATGAACTGGATGG | RRAS2 | ENSG00000133818 | 0.56756511374072 | [49] | [130] | 5 | hSpCas9 | negative selection | 10736428 | 14281663 | 14281686 | 11 | - | 28162770 | SKM1 | viability | GCTTAAGGTAACATACATGGAGG | RRAS2 | ENSG00000133818 | -3.237039197300849 | [15] | [2] | -9 | hSpCas9 | negative selection | 10736429 | 14281688 | 14281711 | 11 | - | 28162770 | PL21 | viability | AAGAAGGACAACAGTTAGCACGG | RRAS2 | ENSG00000133818 | -0.0018032080351657598 | [466] | [202] | 0 | hSpCas9 | negative selection | 10905786 | 14294785 | 14294808 | 11 | - | 28162770 | PL21 | viability | GACTGGCGAAGGCTTCCTGTTGG | RRAS2 | ENSG00000133818 | -1.1490099491330665 | [213] | [41] | -6 | hSpCas9 | negative selection | 10905787 | 14281711 | 14281734 | 11 | - | 28162770 | PL21 | viability | GTTGGAATTTCAGGTAACACAGG | RRAS2 | ENSG00000133818 | 0.7081732367775535 | [397] | [282] | 6 | hSpCas9 | negative selection | 10905788 | 14281678 | 14281701 | 11 | - | 28162770 | PL21 | viability | ACAGTTAGCACGGCAGCTTAAGG | RRAS2 | ENSG00000133818 | 0.20307490551386675 | [490] | [245] | 1 | hSpCas9 | negative selection | 10905789 | 14294832 | 14294855 | 11 | - | 28162770 | PL21 | viability | ACAGCAGGACAAGAAGAGTTTGG | RRAS2 | ENSG00000133818 | -0.24346703698629446 | [135] | [49] | -2 | hSpCas9 | negative selection | 10905790 | 14358813 | 14358836 | 11 | - | 28162770 | PL21 | viability | GGAGAAGTACCGGCTCGTGGTGG | RRAS2 | ENSG00000133818 | 0.6443234594276803 | [146] | [99] | 5 | hSpCas9 | negative selection | 10905791 | 14358861 | 14358884 | 11 | - | 28162770 | PL21 | viability | CTGTAGCGTCCCCATGGCCGCGG | RRAS2 | ENSG00000133818 | 0.04566826545352054 | [324] | [145] | 0 | hSpCas9 | negative selection | 10905792 | 14358823 | 14358846 | 11 | - | 28162770 | PL21 | viability | GCTCCGGCCAGGAGAAGTACCGG | RRAS2 | ENSG00000133818 | 0.9226056389604114 | [239] | [197] | 7 | hSpCas9 | negative selection | 10905793 | 14358757 | 14358780 | 11 | + | 28162770 | PL21 | viability | AGGTACCTGGATGAACTGGATGG | RRAS2 | ENSG00000133818 | -1.1610479108452694 | [148] | [28] | -7 | hSpCas9 | negative selection | 10905794 | 14281663 | 14281686 | 11 | - | 28162770 | PL21 | viability | GCTTAAGGTAACATACATGGAGG | RRAS2 | ENSG00000133818 | -1.232819792786786 | [53] | [9] | -7 | hSpCas9 | negative selection | 10905795 | 14281688 | 14281711 | 11 | - | 28162770 | P31FUJ | viability | AAGAAGGACAACAGTTAGCACGG | RRAS2 | ENSG00000133818 | 0.5179872284893781 | [456] | [768] | 6 | hSpCas9 | negative selection | 11075152 | 14294785 | 14294808 | 11 | - | 28162770 | P31FUJ | viability | GACTGGCGAAGGCTTCCTGTTGG | RRAS2 | ENSG00000133818 | -1.9401613364952615 | [208] | [63] | -8 | hSpCas9 | negative selection | 11075153 | 14281711 | 14281734 | 11 | - | 28162770 | P31FUJ | viability | GTTGGAATTTCAGGTAACACAGG | RRAS2 | ENSG00000133818 | 0.14405210097657717 | [401] | [521] | 1 | hSpCas9 | negative selection | 11075154 | 14281678 | 14281701 | 11 | - | 28162770 | P31FUJ | viability | ACAGTTAGCACGGCAGCTTAAGG | RRAS2 | ENSG00000133818 | 0.4622576627160606 | [495] | [802] | 5 | hSpCas9 | negative selection | 11075155 | 14294832 | 14294855 | 11 | - | 28162770 | P31FUJ | viability | ACAGCAGGACAAGAAGAGTTTGG | RRAS2 | ENSG00000133818 | -0.025477231166872505 | [109] | [126] | 0 | hSpCas9 | negative selection | 11075156 | 14358813 | 14358836 | 11 | - | 28162770 | P31FUJ | viability | GGAGAAGTACCGGCTCGTGGTGG | RRAS2 | ENSG00000133818 | 0.1668052542948592 | [140] | [185] | 1 | hSpCas9 | negative selection | 11075157 | 14358861 | 14358884 | 11 | - | 28162770 | P31FUJ | viability | CTGTAGCGTCCCCATGGCCGCGG | RRAS2 | ENSG00000133818 | 0.16755871823202106 | [493] | [651] | 1 | hSpCas9 | negative selection | 11075158 | 14358823 | 14358846 | 11 | - | 28162770 | P31FUJ | viability | GCTCCGGCCAGGAGAAGTACCGG | RRAS2 | ENSG00000133818 | 0.7801756495838315 | [331] | [669] | 8 | hSpCas9 | negative selection | 11075159 | 14358757 | 14358780 | 11 | + | 28162770 | P31FUJ | viability | AGGTACCTGGATGAACTGGATGG | RRAS2 | ENSG00000133818 | 0.03525901849424798 | [190] | [229] | 0 | hSpCas9 | negative selection | 11075160 | 14281663 | 14281686 | 11 | - | 28162770 | P31FUJ | viability | GCTTAAGGTAACATACATGGAGG | RRAS2 | ENSG00000133818 | -0.296932541834094 | [45] | [43] | -3 | hSpCas9 | negative selection | 11075161 | 14281688 | 14281711 | 11 | - | 28162770 | OCIAML5 | viability | AAGAAGGACAACAGTTAGCACGG | RRAS2 | ENSG00000133818 | 0.6580727531002732 | [276] | [788] | 6 | hSpCas9 | negative selection | 11244518 | 14294785 | 14294808 | 11 | - | 28162770 | OCIAML5 | viability | GACTGGCGAAGGCTTCCTGTTGG | RRAS2 | ENSG00000133818 | -0.9979174373274518 | [103] | [93] | -6 | hSpCas9 | negative selection | 11244519 | 14281711 | 14281734 | 11 | - | 28162770 | OCIAML5 | viability | GTTGGAATTTCAGGTAACACAGG | RRAS2 | ENSG00000133818 | 0.42500728823910494 | [195] | [474] | 3 | hSpCas9 | negative selection | 11244520 | 14281678 | 14281701 | 11 | - | 28162770 | OCIAML5 | viability | ACAGTTAGCACGGCAGCTTAAGG | RRAS2 | ENSG00000133818 | 0.9329853749920363 | [297] | [1026] | 7 | hSpCas9 | negative selection | 11244521 | 14294832 | 14294855 | 11 | - | 28162770 | OCIAML5 | viability | ACAGCAGGACAAGAAGAGTTTGG | RRAS2 | ENSG00000133818 | 0.8461065403051502 | [48] | [158] | 7 | hSpCas9 | negative selection | 11244522 | 14358813 | 14358836 | 11 | - | 28162770 | OCIAML5 | viability | GGAGAAGTACCGGCTCGTGGTGG | RRAS2 | ENSG00000133818 | 0.38562498685533353 | [66] | [157] | 3 | hSpCas9 | negative selection | 11244523 | 14358861 | 14358884 | 11 | - | 28162770 | OCIAML5 | viability | CTGTAGCGTCCCCATGGCCGCGG | RRAS2 | ENSG00000133818 | 1.016927416985993 | [143] | [525] | 8 | hSpCas9 | negative selection | 11244524 | 14358823 | 14358846 | 11 | - | 28162770 | OCIAML5 | viability | GCTCCGGCCAGGAGAAGTACCGG | RRAS2 | ENSG00000133818 | 1.1404388925890787 | [192] | [767] | 8 | hSpCas9 | negative selection | 11244525 | 14358757 | 14358780 | 11 | + | 28162770 | OCIAML5 | viability | AGGTACCTGGATGAACTGGATGG | RRAS2 | ENSG00000133818 | 0.04730106602951195 | [140] | [262] | 0 | hSpCas9 | negative selection | 11244526 | 14281663 | 14281686 | 11 | - | 28162770 | OCIAML5 | viability | GCTTAAGGTAACATACATGGAGG | RRAS2 | ENSG00000133818 | 0.6954212244384962 | [38] | [113] | 6 | hSpCas9 | negative selection | 11244527 | 14281688 | 14281711 | 11 | - | 28162770 | EOL1 | viability | AAGAAGGACAACAGTTAGCACGG | RRAS2 | ENSG00000133818 | 0.5292991706940433 | [892] | [678] | 5 | hSpCas9 | negative selection | 11413884 | 14294785 | 14294808 | 11 | - | 28162770 | EOL1 | viability | GACTGGCGAAGGCTTCCTGTTGG | RRAS2 | ENSG00000133818 | -1.4246017920518521 | [320] | [62] | -7 | hSpCas9 | negative selection | 11413885 | 14281711 | 14281734 | 11 | - | 28162770 | EOL1 | viability | GTTGGAATTTCAGGTAACACAGG | RRAS2 | ENSG00000133818 | 0.5042490706879739 | [640] | [478] | 4 | hSpCas9 | negative selection | 11413886 | 14281678 | 14281701 | 11 | - | 28162770 | EOL1 | viability | ACAGTTAGCACGGCAGCTTAAGG | RRAS2 | ENSG00000133818 | 0.9017318763183226 | [955] | [940] | 7 | hSpCas9 | negative selection | 11413887 | 14294832 | 14294855 | 11 | - | 28162770 | EOL1 | viability | ACAGCAGGACAAGAAGAGTTTGG | RRAS2 | ENSG00000133818 | 1.1960579594716734 | [197] | [238] | 8 | hSpCas9 | negative selection | 11413888 | 14358813 | 14358836 | 11 | - | 28162770 | EOL1 | viability | GGAGAAGTACCGGCTCGTGGTGG | RRAS2 | ENSG00000133818 | 0.1505514464593613 | [341] | [199] | 1 | hSpCas9 | negative selection | 11413889 | 14358861 | 14358884 | 11 | - | 28162770 | EOL1 | viability | CTGTAGCGTCCCCATGGCCGCGG | RRAS2 | ENSG00000133818 | -0.1749879019803799 | [389] | [181] | -1 | hSpCas9 | negative selection | 11413890 | 14358823 | 14358846 | 11 | - | 28162770 | EOL1 | viability | GCTCCGGCCAGGAGAAGTACCGG | RRAS2 | ENSG00000133818 | 0.22722290539342047 | [346] | [213] | 2 | hSpCas9 | negative selection | 11413891 | 14358757 | 14358780 | 11 | + | 28162770 | EOL1 | viability | AGGTACCTGGATGAACTGGATGG | RRAS2 | ENSG00000133818 | 0.5481055176042687 | [208] | [160] | 5 | hSpCas9 | negative selection | 11413892 | 14281663 | 14281686 | 11 | - | 28162770 | EOL1 | viability | GCTTAAGGTAACATACATGGAGG | RRAS2 | ENSG00000133818 | -1.2453772298717776 | [62] | [13] | -7 | hSpCas9 | negative selection | 11413893 | 14281688 | 14281711 | 11 | - | 28162770 | MOLM13 | viability | AAGAAGGACAACAGTTAGCACGG | RRAS2 | ENSG00000133818 | 0.9495588119136751 | [713] | [996] | 7 | hSpCas9 | negative selection | 11583250 | 14294785 | 14294808 | 11 | - | 28162770 | MOLM13 | viability | GACTGGCGAAGGCTTCCTGTTGG | RRAS2 | ENSG00000133818 | -2.8069047377516885 | [270] | [27] | -8 | hSpCas9 | negative selection | 11583251 | 14281711 | 14281734 | 11 | - | 28162770 | MOLM13 | viability | GTTGGAATTTCAGGTAACACAGG | RRAS2 | ENSG00000133818 | 1.4580703205141328 | [515] | [1024] | 9 | hSpCas9 | negative selection | 11583252 | 14281678 | 14281701 | 11 | - | 28162770 | MOLM13 | viability | ACAGTTAGCACGGCAGCTTAAGG | RRAS2 | ENSG00000133818 | 1.3961758727057991 | [762] | [1451] | 9 | hSpCas9 | negative selection | 11583253 | 14294832 | 14294855 | 11 | - | 28162770 | MOLM13 | viability | ACAGCAGGACAAGAAGAGTTTGG | RRAS2 | ENSG00000133818 | 1.2169712620268418 | [165] | [278] | 8 | hSpCas9 | negative selection | 11583254 | 14358813 | 14358836 | 11 | - | 28162770 | MOLM13 | viability | GGAGAAGTACCGGCTCGTGGTGG | RRAS2 | ENSG00000133818 | 0.6173702802198008 | [228] | [253] | 4 | hSpCas9 | negative selection | 11583255 | 14358861 | 14358884 | 11 | - | 28162770 | MOLM13 | viability | CTGTAGCGTCCCCATGGCCGCGG | RRAS2 | ENSG00000133818 | 1.3188596044136163 | [376] | [679] | 8 | hSpCas9 | negative selection | 11583256 | 14358823 | 14358846 | 11 | - | 28162770 | MOLM13 | viability | GCTCCGGCCAGGAGAAGTACCGG | RRAS2 | ENSG00000133818 | 0.1960847660830528 | [395] | [327] | 1 | hSpCas9 | negative selection | 11583257 | 14358757 | 14358780 | 11 | + | 28162770 | MOLM13 | viability | AGGTACCTGGATGAACTGGATGG | RRAS2 | ENSG00000133818 | 0.24289046439364967 | [276] | [236] | 1 | hSpCas9 | negative selection | 11583258 | 14281663 | 14281686 | 11 | - | 28162770 | MOLM13 | viability | GCTTAAGGTAACATACATGGAGG | RRAS2 | ENSG00000133818 | -3.260031073018621 | [105] | [7] | -8 | hSpCas9 | negative selection | 11583259 | 14281688 | 14281711 | 11 | - | 28162770 | HEL | viability | AAGAAGGACAACAGTTAGCACGG | RRAS2 | ENSG00000133818 | 0.6302909977375555 | [581] | [576] | 5 | hSpCas9 | negative selection | 11752616 | 14294785 | 14294808 | 11 | - | 28162770 | HEL | viability | GACTGGCGAAGGCTTCCTGTTGG | RRAS2 | ENSG00000133818 | -2.639815024552861 | [252] | [25] | -8 | hSpCas9 | negative selection | 11752617 | 14281711 | 14281734 | 11 | - | 28162770 | HEL | viability | GTTGGAATTTCAGGTAACACAGG | RRAS2 | ENSG00000133818 | 0.06347869064338418 | [504] | [337] | 0 | hSpCas9 | negative selection | 11752618 | 14281678 | 14281701 | 11 | - | 28162770 | HEL | viability | ACAGTTAGCACGGCAGCTTAAGG | RRAS2 | ENSG00000133818 | 1.0702672754623979 | [689] | [927] | 8 | hSpCas9 | negative selection | 11752619 | 14294832 | 14294855 | 11 | - | 28162770 | HEL | viability | ACAGCAGGACAAGAAGAGTTTGG | RRAS2 | ENSG00000133818 | 0.41877399084515554 | [152] | [130] | 3 | hSpCas9 | negative selection | 11752620 | 14358813 | 14358836 | 11 | - | 28162770 | HEL | viability | GGAGAAGTACCGGCTCGTGGTGG | RRAS2 | ENSG00000133818 | 0.15277284521494766 | [190] | [135] | 1 | hSpCas9 | negative selection | 11752621 | 14358861 | 14358884 | 11 | - | 28162770 | HEL | viability | CTGTAGCGTCCCCATGGCCGCGG | RRAS2 | ENSG00000133818 | 0.39630093669725797 | [362] | [305] | 3 | hSpCas9 | negative selection | 11752622 | 14358823 | 14358846 | 11 | - | 28162770 | HEL | viability | GCTCCGGCCAGGAGAAGTACCGG | RRAS2 | ENSG00000133818 | 1.321386778262947 | [312] | [500] | 9 | hSpCas9 | negative selection | 11752623 | 14358757 | 14358780 | 11 | + | 28162770 | HEL | viability | AGGTACCTGGATGAACTGGATGG | RRAS2 | ENSG00000133818 | 0.37832319576820245 | [208] | [173] | 3 | hSpCas9 | negative selection | 11752624 | 14281663 | 14281686 | 11 | - | 28162770 | HEL | viability | GCTTAAGGTAACATACATGGAGG | RRAS2 | ENSG00000133818 | -2.231730285915784 | [43] | [5] | -8 | hSpCas9 | negative selection | 11752625 | 14281688 | 14281711 | 11 | - | 28162770 | MV411 | viability | AAGAAGGACAACAGTTAGCACGG | RRAS2 | ENSG00000133818 | 0.6973732580462089 | [581] | [794] | 6 | hSpCas9 | negative selection | 11921982 | 14294785 | 14294808 | 11 | - | 28162770 | MV411 | viability | GACTGGCGAAGGCTTCCTGTTGG | RRAS2 | ENSG00000133818 | -2.345019486485305 | [192] | [31] | -8 | hSpCas9 | negative selection | 11921983 | 14281711 | 14281734 | 11 | - | 28162770 | MV411 | viability | GTTGGAATTTCAGGTAACACAGG | RRAS2 | ENSG00000133818 | 0.7890390113452888 | [348] | [507] | 7 | hSpCas9 | negative selection | 11921984 | 14281678 | 14281701 | 11 | - | 28162770 | MV411 | viability | ACAGTTAGCACGGCAGCTTAAGG | RRAS2 | ENSG00000133818 | 0.6426302386647476 | [548] | [721] | 6 | hSpCas9 | negative selection | 11921985 | 14294832 | 14294855 | 11 | - | 28162770 | MV411 | viability | ACAGCAGGACAAGAAGAGTTTGG | RRAS2 | ENSG00000133818 | -0.09204891548889171 | [123] | [97] | 0 | hSpCas9 | negative selection | 11921986 | 14358813 | 14358836 | 11 | - | 28162770 | MV411 | viability | GGAGAAGTACCGGCTCGTGGTGG | RRAS2 | ENSG00000133818 | 0.24743755078277527 | [146] | [146] | 2 | hSpCas9 | negative selection | 11921987 | 14358861 | 14358884 | 11 | - | 28162770 | MV411 | viability | CTGTAGCGTCCCCATGGCCGCGG | RRAS2 | ENSG00000133818 | 0.012378717610166734 | [285] | [242] | 0 | hSpCas9 | negative selection | 11921988 | 14358823 | 14358846 | 11 | - | 28162770 | MV411 | viability | GCTCCGGCCAGGAGAAGTACCGG | RRAS2 | ENSG00000133818 | 0.16943503878150223 | [322] | [305] | 1 | hSpCas9 | negative selection | 11921989 | 14358757 | 14358780 | 11 | + | 28162770 | MV411 | viability | AGGTACCTGGATGAACTGGATGG | RRAS2 | ENSG00000133818 | 0.31899081180780914 | [176] | [185] | 3 | hSpCas9 | negative selection | 11921990 | 14281663 | 14281686 | 11 | - | 28162770 | MV411 | viability | GCTTAAGGTAACATACATGGAGG | RRAS2 | ENSG00000133818 | -4.453002167358317 | [51] | [1] | -9 | hSpCas9 | negative selection | 11921991 | 14281688 | 14281711 | 11 | - | 28162770 | MONOMAC1 | viability | AAGAAGGACAACAGTTAGCACGG | RRAS2 | ENSG00000133818 | 0.15534504436952257 | [299] | [382] | 1 | hSpCas9 | negative selection | 12091348 | 14294785 | 14294808 | 11 | - | 28162770 | MONOMAC1 | viability | GACTGGCGAAGGCTTCCTGTTGG | RRAS2 | ENSG00000133818 | -0.24010556895143964 | [135] | [131] | -2 | hSpCas9 | negative selection | 12091349 | 14281711 | 14281734 | 11 | - | 28162770 | MONOMAC1 | viability | GTTGGAATTTCAGGTAACACAGG | RRAS2 | ENSG00000133818 | 1.606496364045642 | [215] | [753] | 9 | hSpCas9 | negative selection | 12091350 | 14281678 | 14281701 | 11 | - | 28162770 | MONOMAC1 | viability | ACAGTTAGCACGGCAGCTTAAGG | RRAS2 | ENSG00000133818 | 0.18949422453029596 | [344] | [450] | 2 | hSpCas9 | negative selection | 12091351 | 14294832 | 14294855 | 11 | - | 28162770 | MONOMAC1 | viability | ACAGCAGGACAAGAAGAGTTTGG | RRAS2 | ENSG00000133818 | 2.3293309997507547 | [66] | [385] | 9 | hSpCas9 | negative selection | 12091352 | 14358813 | 14358836 | 11 | - | 28162770 | MONOMAC1 | viability | GGAGAAGTACCGGCTCGTGGTGG | RRAS2 | ENSG00000133818 | 0.7941393025534403 | [81] | [162] | 7 | hSpCas9 | negative selection | 12091353 | 14358861 | 14358884 | 11 | - | 28162770 | MONOMAC1 | viability | CTGTAGCGTCCCCATGGCCGCGG | RRAS2 | ENSG00000133818 | 0.7957676515362425 | [200] | [399] | 7 | hSpCas9 | negative selection | 12091354 | 14358823 | 14358846 | 11 | - | 28162770 | MONOMAC1 | viability | GCTCCGGCCAGGAGAAGTACCGG | RRAS2 | ENSG00000133818 | -0.18200863782722176 | [190] | [192] | -1 | hSpCas9 | negative selection | 12091355 | 14358757 | 14358780 | 11 | + | 28162770 | MONOMAC1 | viability | AGGTACCTGGATGAACTGGATGG | RRAS2 | ENSG00000133818 | 0.1345846440316526 | [88] | [111] | 1 | hSpCas9 | negative selection | 12091356 | 14281663 | 14281686 | 11 | - | 28162770 | MONOMAC1 | viability | GCTTAAGGTAACATACATGGAGG | RRAS2 | ENSG00000133818 | -0.9519243492230225 | [26] | [15] | -6 | hSpCas9 | negative selection | 12091357 | 14281688 | 14281711 | 11 | - | 28162770 | OCIAML2 | viability | AAGAAGGACAACAGTTAGCACGG | RRAS2 | ENSG00000133818 | 0.36779375460598795 | [104] | [750] | 3 | hSpCas9 | negative selection | 12260714 | 14294785 | 14294808 | 11 | - | 28162770 | OCIAML2 | viability | GACTGGCGAAGGCTTCCTGTTGG | RRAS2 | ENSG00000133818 | -1.390459476558178 | [34] | [73] | -7 | hSpCas9 | negative selection | 12260715 | 14281711 | 14281734 | 11 | - | 28162770 | OCIAML2 | viability | GTTGGAATTTCAGGTAACACAGG | RRAS2 | ENSG00000133818 | 0.637648626753949 | [84] | [732] | 6 | hSpCas9 | negative selection | 12260716 | 14281678 | 14281701 | 11 | - | 28162770 | OCIAML2 | viability | ACAGTTAGCACGGCAGCTTAAGG | RRAS2 | ENSG00000133818 | 0.5430266192394222 | [91] | [742] | 5 | hSpCas9 | negative selection | 12260717 | 14294832 | 14294855 | 11 | - | 28162770 | OCIAML2 | viability | ACAGCAGGACAAGAAGAGTTTGG | RRAS2 | ENSG00000133818 | -0.40024049735076345 | [24] | [104] | -3 | hSpCas9 | negative selection | 12260718 | 14358813 | 14358836 | 11 | - | 28162770 | OCIAML2 | viability | GGAGAAGTACCGGCTCGTGGTGG | RRAS2 | ENSG00000133818 | 0.7588520208806059 | [28] | [271] | 7 | hSpCas9 | negative selection | 12260719 | 14358861 | 14358884 | 11 | - | 28162770 | OCIAML2 | viability | CTGTAGCGTCCCCATGGCCGCGG | RRAS2 | ENSG00000133818 | 1.273124934586684 | [52] | [709] | 9 | hSpCas9 | negative selection | 12260720 | 14358823 | 14358846 | 11 | - | 28162770 | OCIAML2 | viability | GCTCCGGCCAGGAGAAGTACCGG | RRAS2 | ENSG00000133818 | 0.6168330160081783 | [37] | [322] | 6 | hSpCas9 | negative selection | 12260721 | 14358757 | 14358780 | 11 | + | 28162770 | OCIAML2 | viability | AGGTACCTGGATGAACTGGATGG | RRAS2 | ENSG00000133818 | 0.2111942147315839 | [23] | [153] | 2 | hSpCas9 | negative selection | 12260722 | 14281663 | 14281686 | 11 | - | 28162770 | OCIAML2 | viability | GCTTAAGGTAACATACATGGAGG | RRAS2 | ENSG00000133818 | -3.608133348992096 | [10] | [4] | -9 | hSpCas9 | negative selection | 12260723 | 14281688 | 14281711 | 11 | - | 28162770 | OCIAML3 | viability | AAGAAGGACAACAGTTAGCACGG | RRAS2 | ENSG00000133818 | 0.5240481211975492 | [128] | [559] | 5 | hSpCas9 | negative selection | 12430080 | 14294785 | 14294808 | 11 | - | 28162770 | OCIAML3 | viability | GACTGGCGAAGGCTTCCTGTTGG | RRAS2 | ENSG00000133818 | -1.3583793918310212 | [61] | [72] | -7 | hSpCas9 | negative selection | 12430081 | 14281711 | 14281734 | 11 | - | 28162770 | OCIAML3 | viability | GTTGGAATTTCAGGTAACACAGG | RRAS2 | ENSG00000133818 | -0.5693455860898939 | [115] | [235] | -4 | hSpCas9 | negative selection | 12430082 | 14281678 | 14281701 | 11 | - | 28162770 | OCIAML3 | viability | ACAGTTAGCACGGCAGCTTAAGG | RRAS2 | ENSG00000133818 | 0.9245937548311158 | [151] | [870] | 7 | hSpCas9 | negative selection | 12430083 | 14294832 | 14294855 | 11 | - | 28162770 | OCIAML3 | viability | ACAGCAGGACAAGAAGAGTTTGG | RRAS2 | ENSG00000133818 | 0.5944374490889471 | [42] | [195] | 5 | hSpCas9 | negative selection | 12430084 | 14358813 | 14358836 | 11 | - | 28162770 | OCIAML3 | viability | GGAGAAGTACCGGCTCGTGGTGG | RRAS2 | ENSG00000133818 | 0.9067944127329945 | [49] | [282] | 7 | hSpCas9 | negative selection | 12430085 | 14358861 | 14358884 | 11 | - | 28162770 | OCIAML3 | viability | CTGTAGCGTCCCCATGGCCGCGG | RRAS2 | ENSG00000133818 | 0.8128093521497122 | [98] | [524] | 7 | hSpCas9 | negative selection | 12430086 | 14358823 | 14358846 | 11 | - | 28162770 | OCIAML3 | viability | GCTCCGGCCAGGAGAAGTACCGG | RRAS2 | ENSG00000133818 | 0.4059923596758369 | [72] | [291] | 4 | hSpCas9 | negative selection | 12430087 | 14358757 | 14358780 | 11 | + | 28162770 | OCIAML3 | viability | AGGTACCTGGATGAACTGGATGG | RRAS2 | ENSG00000133818 | 1.1596366949886732 | [42] | [289] | 8 | hSpCas9 | negative selection | 12430088 | 14281663 | 14281686 | 11 | - | 28162770 | OCIAML3 | viability | GCTTAAGGTAACATACATGGAGG | RRAS2 | ENSG00000133818 | -3.4013625623817676 | [13] | [3] | -9 | hSpCas9 | negative selection | 12430089 |