Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:81847
• Symbol:Rnf146
• Description:ring finger protein 146

DataSource: http://genomecrispr.dkfz.de/#!/results/Rnf146

Export (tab separated) Export to Excel

Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
127287316	127287339	6	-	26472758	Jiyoye	viability	GAAGTGCTTGCATCAGGGGATGG	RNF146	ENSG00000118518	0.0968352608937228	[123]	[99]	0	hSpCas9	negative selection	138014
127287422	127287445	6	+	26472758	Jiyoye	viability	ATGAATCACCATCTTCAGGCAGG	RNF146	ENSG00000118518	-0.177787119215283	[77]	[51]	-1	hSpCas9	negative selection	138015
127286832	127286855	6	+	26472758	Jiyoye	viability	TTGTCGACAAGAAATTCCCGAGG	RNF146	ENSG00000118518	-0.09464588391503687	[176]	[124]	0	hSpCas9	negative selection	138016
127286890	127286913	6	+	26472758	Jiyoye	viability	GAACTCAAGGCAGCAAGTAGAGG	RNF146	ENSG00000118518	-0.16398131969025243	[363]	[244]	-1	hSpCas9	negative selection	138017
127286877	127286900	6	+	26472758	Jiyoye	viability	GTTGTCACCAGAAGAACTCAAGG	RNF146	ENSG00000118518	0.20687673102004234	[323]	[281]	1	hSpCas9	negative selection	138018
127287388	127287411	6	+	26472758	Jiyoye	viability	GAAAGGAGTCATAGGGGAGAAGG	RNF146	ENSG00000118518	0.9345606066502145	[212]	[306]	6	hSpCas9	negative selection	138019
127286967	127286990	6	+	26472758	Jiyoye	viability	TGAGCGCACTAGTAGAGAGCTGG	RNF146	ENSG00000118518	1.01722886318986	[75]	[115]	6	hSpCas9	negative selection	138020
127287190	127287213	6	+	26472758	Jiyoye	viability	GCAAGAGAGAGCTCTGCTGACGG	RNF146	ENSG00000118518	0.053123083562871876	[192]	[150]	0	hSpCas9	negative selection	138021
127287217	127287240	6	+	26472758	Jiyoye	viability	GACAGTGTATCAGCACAGAGTGG	RNF146	ENSG00000118518	-0.05722819509394994	[108]	[78]	0	hSpCas9	negative selection	138022
127287253	127287276	6	-	26472758	Jiyoye	viability	GGCCTTACAGAAGACACTAGGGG	RNF146	ENSG00000118518	-2.7779360237511153	[190]	[20]	-9	hSpCas9	negative selection	138023
127287316	127287339	6	-	26472758	KBM7	viability	GAAGTGCTTGCATCAGGGGATGG	RNF146	ENSG00000118518	0.6191087465655774	[205,246]	[186,146]	6	hSpCas9	negative selection	329132
127287422	127287445	6	+	26472758	KBM7	viability	ATGAATCACCATCTTCAGGCAGG	RNF146	ENSG00000118518	-1.1341176089696459	[431,256]	[95,50]	-7	hSpCas9	negative selection	329133
127286832	127286855	6	+	26472758	KBM7	viability	TTGTCGACAAGAAATTCCCGAGG	RNF146	ENSG00000118518	-0.19002572076806562	[470,232]	[163,119]	-2	hSpCas9	negative selection	329134
127286890	127286913	6	+	26472758	KBM7	viability	GAACTCAAGGCAGCAAGTAGAGG	RNF146	ENSG00000118518	0.3205610278269475	[1161,1135]	[758,603]	3	hSpCas9	negative selection	329135
127286877	127286900	6	+	26472758	KBM7	viability	GTTGTCACCAGAAGAACTCAAGG	RNF146	ENSG00000118518	-0.4869166687206705	[841,961]	[425,198]	-4	hSpCas9	negative selection	329136
127287388	127287411	6	+	26472758	KBM7	viability	GAAAGGAGTCATAGGGGAGAAGG	RNF146	ENSG00000118518	-0.07836824518436836	[763,906]	[383,370]	-1	hSpCas9	negative selection	329137
127286967	127286990	6	+	26472758	KBM7	viability	TGAGCGCACTAGTAGAGAGCTGG	RNF146	ENSG00000118518	-0.40838543614845624	[434,493]	[214,122]	-4	hSpCas9	negative selection	329138
127287190	127287213	6	+	26472758	KBM7	viability	GCAAGAGAGAGCTCTGCTGACGG	RNF146	ENSG00000118518	-0.5752144088229157	[671,493]	[162,198]	-5	hSpCas9	negative selection	329139
127287217	127287240	6	+	26472758	KBM7	viability	GACAGTGTATCAGCACAGAGTGG	RNF146	ENSG00000118518	-0.17414821625514812	[366,476]	[177,179]	-2	hSpCas9	negative selection	329140
127287253	127287276	6	-	26472758	KBM7	viability	GGCCTTACAGAAGACACTAGGGG	RNF146	ENSG00000118518	0.10168787235662302	[192,169]	[73,106]	1	hSpCas9	negative selection	329141
127287316	127287339	6	-	26472758	Raji	viability	GAAGTGCTTGCATCAGGGGATGG	RNF146	ENSG00000118518	-0.08526154256879648	[127]	[27]	0	hSpCas9	negative selection	520250
127287422	127287445	6	+	26472758	Raji	viability	ATGAATCACCATCTTCAGGCAGG	RNF146	ENSG00000118518	-0.7363132337477252	[200]	[27]	-5	hSpCas9	negative selection	520251
127286832	127286855	6	+	26472758	Raji	viability	TTGTCGACAAGAAATTCCCGAGG	RNF146	ENSG00000118518	0.5455046477654847	[185]	[62]	5	hSpCas9	negative selection	520252
127286890	127286913	6	+	26472758	Raji	viability	GAACTCAAGGCAGCAAGTAGAGG	RNF146	ENSG00000118518	-0.485846581331157	[524]	[86]	-4	hSpCas9	negative selection	520253
127286877	127286900	6	+	26472758	Raji	viability	GTTGTCACCAGAAGAACTCAAGG	RNF146	ENSG00000118518	0.11987447955679642	[344]	[86]	1	hSpCas9	negative selection	520254
127287388	127287411	6	+	26472758	Raji	viability	GAAAGGAGTCATAGGGGAGAAGG	RNF146	ENSG00000118518	0.2292758403941103	[396]	[107]	2	hSpCas9	negative selection	520255
127286967	127286990	6	+	26472758	Raji	viability	TGAGCGCACTAGTAGAGAGCTGG	RNF146	ENSG00000118518	-0.2868954037384468	[183]	[34]	-2	hSpCas9	negative selection	520256
127287190	127287213	6	+	26472758	Raji	viability	GCAAGAGAGAGCTCTGCTGACGG	RNF146	ENSG00000118518	0.2367770570898572	[372]	[101]	2	hSpCas9	negative selection	520257
127287217	127287240	6	+	26472758	Raji	viability	GACAGTGTATCAGCACAGAGTGG	RNF146	ENSG00000118518	0.13980501306597698	[175]	[44]	1	hSpCas9	negative selection	520258
127287253	127287276	6	-	26472758	Raji	viability	GGCCTTACAGAAGACACTAGGGG	RNF146	ENSG00000118518	1.317306604747831	[82]	[47]	9	hSpCas9	negative selection	520259
127287316	127287339	6	-	26472758	K562	viability	GAAGTGCTTGCATCAGGGGATGG	RNF146	ENSG00000118518	0.14034627351876017	[272]	[253]	1	hSpCas9	negative selection	711368
127287422	127287445	6	+	26472758	K562	viability	ATGAATCACCATCTTCAGGCAGG	RNF146	ENSG00000118518	1.4505798782444792	[165]	[382]	9	hSpCas9	negative selection	711369
127286832	127286855	6	+	26472758	K562	viability	TTGTCGACAAGAAATTCCCGAGG	RNF146	ENSG00000118518	-0.15485145575408044	[272]	[206]	-1	hSpCas9	negative selection	711370
127286890	127286913	6	+	26472758	K562	viability	GAACTCAAGGCAGCAAGTAGAGG	RNF146	ENSG00000118518	-0.7166053050755502	[1058]	[543]	-4	hSpCas9	negative selection	711371
127286877	127286900	6	+	26472758	K562	viability	GTTGTCACCAGAAGAACTCAAGG	RNF146	ENSG00000118518	0.4526496115791592	[701]	[810]	3	hSpCas9	negative selection	711372
127287388	127287411	6	+	26472758	K562	viability	GAAAGGAGTCATAGGGGAGAAGG	RNF146	ENSG00000118518	0.3285738260619415	[898]	[952]	2	hSpCas9	negative selection	711373
127286967	127286990	6	+	26472758	K562	viability	TGAGCGCACTAGTAGAGAGCTGG	RNF146	ENSG00000118518	-0.43442694793451075	[372]	[232]	-3	hSpCas9	negative selection	711374
127287190	127287213	6	+	26472758	K562	viability	GCAAGAGAGAGCTCTGCTGACGG	RNF146	ENSG00000118518	0.00663873700355011	[486]	[412]	0	hSpCas9	negative selection	711375
127287217	127287240	6	+	26472758	K562	viability	GACAGTGTATCAGCACAGAGTGG	RNF146	ENSG00000118518	0.5180668075250926	[315]	[381]	4	hSpCas9	negative selection	711376
127287253	127287276	6	-	26472758	K562	viability	GGCCTTACAGAAGACACTAGGGG	RNF146	ENSG00000118518	0.16987177430139289	[138]	[131]	1	hSpCas9	negative selection	711377
127286801	127286824	6	+	26627737	DLD1	viability	GAGCTTCATGGCTTGGAAAGCGG	RNF146	ENSG00000118518	0.8957191297296596	[463]	[250,286,271]	8	hSpCas9	negative selection	830417
127286832	127286855	6	+	26627737	DLD1	viability	TTGTCGACAAGAAATTCCCGAGG	RNF146	ENSG00000118518	0.9457484992432312	[620]	[404,426,302]	8	hSpCas9	negative selection	830418
127286873	127286896	6	-	26627737	DLD1	viability	GAGTTCTTCTGGTGACAACAAGG	RNF146	ENSG00000118518	0.7734672124704068	[303]	[129,272,98]	7	hSpCas9	negative selection	830419
127287217	127287240	6	+	26627737	DLD1	viability	GACAGTGTATCAGCACAGAGTGG	RNF146	ENSG00000118518	1.3423277055787053	[336]	[210,331,261]	9	hSpCas9	negative selection	830420
127287602	127287625	6	+	26627737	DLD1	viability	GAACTGATCGATCAGTAGCAGGG	RNF146	ENSG00000118518	-0.2480630391818759	[313]	[50,60,127]	-3	hSpCas9	negative selection	830421
127287604	127287627	6	+	26627737	DLD1	viability	ACTGATCGATCAGTAGCAGGGGG	RNF146	ENSG00000118518	-0.469769737657717	[238]	[99,24,37]	-5	hSpCas9	negative selection	830422
127286801	127286824	6	+	26627737	GBM cells	viability after 5 days	GAGCTTCATGGCTTGGAAAGCGG	RNF146	ENSG00000118518	1.052264651792482	[106]	[103,133]	9	hSpCas9	negative selection	912732
127286832	127286855	6	+	26627737	GBM cells	viability after 5 days	TTGTCGACAAGAAATTCCCGAGG	RNF146	ENSG00000118518	-0.042192436060745964	[527]	[258,290]	0	hSpCas9	negative selection	912733
127286873	127286896	6	-	26627737	GBM cells	viability after 5 days	GAGTTCTTCTGGTGACAACAAGG	RNF146	ENSG00000118518	0.39674378388086734	[181]	[125,130]	6	hSpCas9	negative selection	912734
127287217	127287240	6	+	26627737	GBM cells	viability after 5 days	GACAGTGTATCAGCACAGAGTGG	RNF146	ENSG00000118518	0.3328104014158454	[227]	[150,156]	5	hSpCas9	negative selection	912735
127287602	127287625	6	+	26627737	GBM cells	viability after 5 days	GAACTGATCGATCAGTAGCAGGG	RNF146	ENSG00000118518	0.10200574026319714	[171]	[126,70]	1	hSpCas9	negative selection	912736
127287604	127287627	6	+	26627737	GBM cells	viability after 5 days	ACTGATCGATCAGTAGCAGGGGG	RNF146	ENSG00000118518	-0.6497067787717503	[97]	[28,37]	-8	hSpCas9	negative selection	912737
127286801	127286824	6	+	26627737	GBM cells	viability after 13 days	GAGCTTCATGGCTTGGAAAGCGG	RNF146	ENSG00000118518	1.1875996161478872	[106]	[118,142]	9	hSpCas9	negative selection	995047
127286832	127286855	6	+	26627737	GBM cells	viability after 13 days	TTGTCGACAAGAAATTCCCGAGG	RNF146	ENSG00000118518	0.314246754188507	[527]	[412,309]	4	hSpCas9	negative selection	995048
127286873	127286896	6	-	26627737	GBM cells	viability after 13 days	GAGTTCTTCTGGTGACAACAAGG	RNF146	ENSG00000118518	0.5659483469269989	[181]	[170,125]	7	hSpCas9	negative selection	995049
127287217	127287240	6	+	26627737	GBM cells	viability after 13 days	GACAGTGTATCAGCACAGAGTGG	RNF146	ENSG00000118518	0.7912748172417107	[227]	[255,179]	8	hSpCas9	negative selection	995050
127287602	127287625	6	+	26627737	GBM cells	viability after 13 days	GAACTGATCGATCAGTAGCAGGG	RNF146	ENSG00000118518	0.23410879847776866	[171]	[122,98]	3	hSpCas9	negative selection	995051
127287604	127287627	6	+	26627737	GBM cells	viability after 13 days	ACTGATCGATCAGTAGCAGGGGG	RNF146	ENSG00000118518	-1.2984691220633735	[97]	[14,26]	-8	hSpCas9	negative selection	995052
127286801	127286824	6	+	26627737	GBM cells	viability after 21 days	GAGCTTCATGGCTTGGAAAGCGG	RNF146	ENSG00000118518	1.3599774738909884	[106]	[155,142]	9	hSpCas9	negative selection	1077362
127286832	127286855	6	+	26627737	GBM cells	viability after 21 days	TTGTCGACAAGAAATTCCCGAGG	RNF146	ENSG00000118518	0.6284125931626576	[527]	[444,441]	6	hSpCas9	negative selection	1077363
127286873	127286896	6	-	26627737	GBM cells	viability after 21 days	GAGTTCTTCTGGTGACAACAAGG	RNF146	ENSG00000118518	0.6688960667882063	[181]	[175,139]	6	hSpCas9	negative selection	1077364
127287217	127287240	6	+	26627737	GBM cells	viability after 21 days	GACAGTGTATCAGCACAGAGTGG	RNF146	ENSG00000118518	0.6241845089467167	[227]	[180,199]	6	hSpCas9	negative selection	1077365
127287602	127287625	6	+	26627737	GBM cells	viability after 21 days	GAACTGATCGATCAGTAGCAGGG	RNF146	ENSG00000118518	0.28966809266512605	[171]	[108,118]	3	hSpCas9	negative selection	1077366
127287604	127287627	6	+	26627737	GBM cells	viability after 21 days	ACTGATCGATCAGTAGCAGGGGG	RNF146	ENSG00000118518	-2.093187428428623	[97]	[12,11]	-9	hSpCas9	negative selection	1077367
127286801	127286824	6	+	26627737	RPE1	viability after 9 days	GAGCTTCATGGCTTGGAAAGCGG	RNF146	ENSG00000118518	1.443622946393992	[824]	[533,919]	7	hSpCas9	negative selection	1159677
127286832	127286855	6	+	26627737	RPE1	viability after 9 days	TTGTCGACAAGAAATTCCCGAGG	RNF146	ENSG00000118518	1.1154642976211824	[1711]	[983,1389]	6	hSpCas9	negative selection	1159678
127286873	127286896	6	-	26627737	RPE1	viability after 9 days	GAGTTCTTCTGGTGACAACAAGG	RNF146	ENSG00000118518	1.549755009655927	[551]	[291,781]	8	hSpCas9	negative selection	1159679
127287217	127287240	6	+	26627737	RPE1	viability after 9 days	GACAGTGTATCAGCACAGAGTGG	RNF146	ENSG00000118518	2.877742836605571	[391]	[629,1252]	9	hSpCas9	negative selection	1159680
127287602	127287625	6	+	26627737	RPE1	viability after 9 days	GAACTGATCGATCAGTAGCAGGG	RNF146	ENSG00000118518	-0.309767014253007	[982]	[232,267]	-2	hSpCas9	negative selection	1159681
127287604	127287627	6	+	26627737	RPE1	viability after 9 days	ACTGATCGATCAGTAGCAGGGGG	RNF146	ENSG00000118518	7.425433953167649	[1]	[80,141]	9	hSpCas9	negative selection	1159682
127286801	127286824	6	+	26627737	RPE1	viability after 12 days	GAGCTTCATGGCTTGGAAAGCGG	RNF146	ENSG00000118518	1.7346677112644595	[824]	[657,821]	8	hSpCas9	negative selection	1241992
127286832	127286855	6	+	26627737	RPE1	viability after 12 days	TTGTCGACAAGAAATTCCCGAGG	RNF146	ENSG00000118518	1.759382959731912	[1711]	[1614,1495]	8	hSpCas9	negative selection	1241993
127286873	127286896	6	-	26627737	RPE1	viability after 12 days	GAGTTCTTCTGGTGACAACAAGG	RNF146	ENSG00000118518	1.8917738254720797	[551]	[510,591]	8	hSpCas9	negative selection	1241994
127287217	127287240	6	+	26627737	RPE1	viability after 12 days	GACAGTGTATCAGCACAGAGTGG	RNF146	ENSG00000118518	3.0121870664802306	[391]	[651,1058]	9	hSpCas9	negative selection	1241995
127287602	127287625	6	+	26627737	RPE1	viability after 12 days	GAACTGATCGATCAGTAGCAGGG	RNF146	ENSG00000118518	-0.5869104832788643	[982]	[152,199]	-4	hSpCas9	negative selection	1241996
127287604	127287627	6	+	26627737	RPE1	viability after 12 days	ACTGATCGATCAGTAGCAGGGGG	RNF146	ENSG00000118518	6.786419123086052	[1]	[1,119]	9	hSpCas9	negative selection	1241997
127286801	127286824	6	+	26627737	RPE1	viability after 15 days	GAGCTTCATGGCTTGGAAAGCGG	RNF146	ENSG00000118518	1.5162399444166992	[824]	[551,778]	7	hSpCas9	negative selection	1324307
127286832	127286855	6	+	26627737	RPE1	viability after 15 days	TTGTCGACAAGAAATTCCCGAGG	RNF146	ENSG00000118518	2.0884522171994586	[1711]	[2220,1903]	8	hSpCas9	negative selection	1324308
127286873	127286896	6	-	26627737	RPE1	viability after 15 days	GAGTTCTTCTGGTGACAACAAGG	RNF146	ENSG00000118518	2.110778065876261	[551]	[536,806]	9	hSpCas9	negative selection	1324309
127287217	127287240	6	+	26627737	RPE1	viability after 15 days	GACAGTGTATCAGCACAGAGTGG	RNF146	ENSG00000118518	3.1056096403594653	[391]	[814,1088]	9	hSpCas9	negative selection	1324310
127287602	127287625	6	+	26627737	RPE1	viability after 15 days	GAACTGATCGATCAGTAGCAGGG	RNF146	ENSG00000118518	0.2174652905421961	[982]	[305,339]	1	hSpCas9	negative selection	1324311
127287604	127287627	6	+	26627737	RPE1	viability after 15 days	ACTGATCGATCAGTAGCAGGGGG	RNF146	ENSG00000118518	7.1935205913849085	[1]	[8,153]	9	hSpCas9	negative selection	1324312
127286801	127286824	6	+	26627737	RPE1	viability after 18 days	GAGCTTCATGGCTTGGAAAGCGG	RNF146	ENSG00000118518	1.9395342294182853	[824]	[766,946]	8	hSpCas9	negative selection	1406622
127286832	127286855	6	+	26627737	RPE1	viability after 18 days	TTGTCGACAAGAAATTCCCGAGG	RNF146	ENSG00000118518	2.4375373095880164	[1711]	[2409,2601]	9	hSpCas9	negative selection	1406623
127286873	127286896	6	-	26627737	RPE1	viability after 18 days	GAGTTCTTCTGGTGACAACAAGG	RNF146	ENSG00000118518	2.267621424317097	[551]	[580,862]	9	hSpCas9	negative selection	1406624
127287217	127287240	6	+	26627737	RPE1	viability after 18 days	GACAGTGTATCAGCACAGAGTGG	RNF146	ENSG00000118518	3.4785383737613684	[391]	[1038,1328]	9	hSpCas9	negative selection	1406625
127287602	127287625	6	+	26627737	RPE1	viability after 18 days	GAACTGATCGATCAGTAGCAGGG	RNF146	ENSG00000118518	-0.06703513573604247	[982]	[332,167]	0	hSpCas9	negative selection	1406626
127287604	127287627	6	+	26627737	RPE1	viability after 18 days	ACTGATCGATCAGTAGCAGGGGG	RNF146	ENSG00000118518	6.584310839683648	[1]	[1,104]	9	hSpCas9	negative selection	1406627
127286801	127286824	6	+	26627737	HeLa	viability after 8 days	GAGCTTCATGGCTTGGAAAGCGG	RNF146	ENSG00000118518	0.6589873694757142	[531]	[438,415,264]	5	hSpCas9	negative selection	1488937
127286832	127286855	6	+	26627737	HeLa	viability after 8 days	TTGTCGACAAGAAATTCCCGAGG	RNF146	ENSG00000118518	-0.3594506680651013	[991]	[380,313,324]	-4	hSpCas9	negative selection	1488938
127286873	127286896	6	-	26627737	HeLa	viability after 8 days	GAGTTCTTCTGGTGACAACAAGG	RNF146	ENSG00000118518	0.1484706687849343	[322]	[147,107,205]	1	hSpCas9	negative selection	1488939
127287217	127287240	6	+	26627737	HeLa	viability after 8 days	GACAGTGTATCAGCACAGAGTGG	RNF146	ENSG00000118518	0.4486877147415934	[266]	[124,283,65]	4	hSpCas9	negative selection	1488940
127287602	127287625	6	+	26627737	HeLa	viability after 8 days	GAACTGATCGATCAGTAGCAGGG	RNF146	ENSG00000118518	-0.8111971764951776	[511]	[279,72,65]	-7	hSpCas9	negative selection	1488941
127287604	127287627	6	+	26627737	HeLa	viability after 8 days	ACTGATCGATCAGTAGCAGGGGG	RNF146	ENSG00000118518	0.8832858994933013	[94]	[74,84,68]	7	hSpCas9	negative selection	1488942
127286801	127286824	6	+	26627737	HeLa	viability after 12 days	GAGCTTCATGGCTTGGAAAGCGG	RNF146	ENSG00000118518	0.6576364336786902	[531]	[453,257,340]	5	hSpCas9	negative selection	1571252
127286832	127286855	6	+	26627737	HeLa	viability after 12 days	TTGTCGACAAGAAATTCCCGAGG	RNF146	ENSG00000118518	-0.4649066742018273	[991]	[425,266,204]	-4	hSpCas9	negative selection	1571253
127286873	127286896	6	-	26627737	HeLa	viability after 12 days	GAGTTCTTCTGGTGACAACAAGG	RNF146	ENSG00000118518	0.15355205945256306	[322]	[116,124,204]	1	hSpCas9	negative selection	1571254
127287217	127287240	6	+	26627737	HeLa	viability after 12 days	GACAGTGTATCAGCACAGAGTGG	RNF146	ENSG00000118518	-0.4016215155590982	[266]	[51,70,127]	-4	hSpCas9	negative selection	1571255
127287602	127287625	6	+	26627737	HeLa	viability after 12 days	GAACTGATCGATCAGTAGCAGGG	RNF146	ENSG00000118518	0.04742068846669828	[511]	[374,100,196]	0	hSpCas9	negative selection	1571256
127287604	127287627	6	+	26627737	HeLa	viability after 12 days	ACTGATCGATCAGTAGCAGGGGG	RNF146	ENSG00000118518	1.0049089457350522	[94]	[151,73,12]	7	hSpCas9	negative selection	1571257
127286801	127286824	6	+	26627737	HeLa	viability after 15 days	GAGCTTCATGGCTTGGAAAGCGG	RNF146	ENSG00000118518	0.4926531650309557	[531]	[308,277,328]	4	hSpCas9	negative selection	1653567
127286832	127286855	6	+	26627737	HeLa	viability after 15 days	TTGTCGACAAGAAATTCCCGAGG	RNF146	ENSG00000118518	-0.2517296564586926	[991]	[379,418,207]	-2	hSpCas9	negative selection	1653568
127286873	127286896	6	-	26627737	HeLa	viability after 15 days	GAGTTCTTCTGGTGACAACAAGG	RNF146	ENSG00000118518	0.37284169419245317	[322]	[158,144,209]	3	hSpCas9	negative selection	1653569
127287217	127287240	6	+	26627737	HeLa	viability after 15 days	GACAGTGTATCAGCACAGAGTGG	RNF146	ENSG00000118518	0.6495599743579004	[266]	[201,115,194]	5	hSpCas9	negative selection	1653570
127287602	127287625	6	+	26627737	HeLa	viability after 15 days	GAACTGATCGATCAGTAGCAGGG	RNF146	ENSG00000118518	-1.3386908175364651	[511]	[68,112,63]	-8	hSpCas9	negative selection	1653571
127287604	127287627	6	+	26627737	HeLa	viability after 15 days	ACTGATCGATCAGTAGCAGGGGG	RNF146	ENSG00000118518	-0.5755709489227776	[94]	[19,6,52]	-5	hSpCas9	negative selection	1653572
127286801	127286824	6	+	26627737	HeLa	viability after 18 days	GAGCTTCATGGCTTGGAAAGCGG	RNF146	ENSG00000118518	0.5002223936360771	[531]	[208,231,328]	4	hSpCas9	negative selection	1735882
127286832	127286855	6	+	26627737	HeLa	viability after 18 days	TTGTCGACAAGAAATTCCCGAGG	RNF146	ENSG00000118518	-0.2502475997781457	[991]	[249,353,207]	-2	hSpCas9	negative selection	1735883
127286873	127286896	6	-	26627737	HeLa	viability after 18 days	GAGTTCTTCTGGTGACAACAAGG	RNF146	ENSG00000118518	0.40755180222166404	[322]	[113,120,209]	3	hSpCas9	negative selection	1735884
127287217	127287240	6	+	26627737	HeLa	viability after 18 days	GACAGTGTATCAGCACAGAGTGG	RNF146	ENSG00000118518	0.6984142497643726	[266]	[142,100,194]	5	hSpCas9	negative selection	1735885
127287602	127287625	6	+	26627737	HeLa	viability after 18 days	GAACTGATCGATCAGTAGCAGGG	RNF146	ENSG00000118518	-1.3654900644803398	[511]	[42,93,63]	-8	hSpCas9	negative selection	1735886
127287604	127287627	6	+	26627737	HeLa	viability after 18 days	ACTGATCGATCAGTAGCAGGGGG	RNF146	ENSG00000118518	-0.4992137298847008	[94]	[15,5,52]	-4	hSpCas9	negative selection	1735887
127286801	127286824	6	+	26627737	HCT116	viability after 6 days	GAGCTTCATGGCTTGGAAAGCGG	RNF146	ENSG00000118518	0.6354139673010089	[1246]	[241,338]	3	hSpCas9	negative selection	1818197
127286832	127286855	6	+	26627737	HCT116	viability after 6 days	TTGTCGACAAGAAATTCCCGAGG	RNF146	ENSG00000118518	0.7037750397869962	[1102]	[255,296]	4	hSpCas9	negative selection	1818198
127286873	127286896	6	-	26627737	HCT116	viability after 6 days	GAGTTCTTCTGGTGACAACAAGG	RNF146	ENSG00000118518	-0.6005596892988141	[362]	[94,5]	-3	hSpCas9	negative selection	1818199
127287217	127287240	6	+	26627737	HCT116	viability after 6 days	GACAGTGTATCAGCACAGAGTGG	RNF146	ENSG00000118518	0.9134165367127436	[894]	[70,371]	5	hSpCas9	negative selection	1818200
127287602	127287625	6	+	26627737	HCT116	viability after 6 days	GAACTGATCGATCAGTAGCAGGG	RNF146	ENSG00000118518	-1.360223063765532	[327]	[41,7]	-7	hSpCas9	negative selection	1818201
127287604	127287627	6	+	26627737	HCT116	viability after 6 days	ACTGATCGATCAGTAGCAGGGGG	RNF146	ENSG00000118518	-0.032024561707982846	[173]	[38,19]	0	hSpCas9	negative selection	1818202
127286801	127286824	6	+	26627737	HCT116	viability after 8 days	GAGCTTCATGGCTTGGAAAGCGG	RNF146	ENSG00000118518	-0.09814415363094153	[707]	[432,409,252]	-1	hSpCas9	negative selection	1900512
127286832	127286855	6	+	26627737	HCT116	viability after 8 days	TTGTCGACAAGAAATTCCCGAGG	RNF146	ENSG00000118518	-0.1810791615134888	[728]	[395,338,328]	-2	hSpCas9	negative selection	1900513
127286873	127286896	6	-	26627737	HCT116	viability after 8 days	GAGTTCTTCTGGTGACAACAAGG	RNF146	ENSG00000118518	0.5806725351042001	[243]	[239,168,194]	6	hSpCas9	negative selection	1900514
127287217	127287240	6	+	26627737	HCT116	viability after 8 days	GACAGTGTATCAGCACAGAGTGG	RNF146	ENSG00000118518	-0.05428510829868986	[301]	[105,227,145]	0	hSpCas9	negative selection	1900515
127287602	127287625	6	+	26627737	HCT116	viability after 8 days	GAACTGATCGATCAGTAGCAGGG	RNF146	ENSG00000118518	-0.5629049743472152	[361]	[140,112,150]	-6	hSpCas9	negative selection	1900516
127287604	127287627	6	+	26627737	HCT116	viability after 8 days	ACTGATCGATCAGTAGCAGGGGG	RNF146	ENSG00000118518	-1.0206801346664147	[169]	[37,23,75]	-8	hSpCas9	negative selection	1900517
127286801	127286824	6	+	26627737	HCT116	viability after 9 days	GAGCTTCATGGCTTGGAAAGCGG	RNF146	ENSG00000118518	-0.40807490324891005	[1246]	[303,208]	-3	hSpCas9	negative selection	1982827
127286832	127286855	6	+	26627737	HCT116	viability after 9 days	TTGTCGACAAGAAATTCCCGAGG	RNF146	ENSG00000118518	0.0675944003833413	[1102]	[373,256]	0	hSpCas9	negative selection	1982828
127286873	127286896	6	-	26627737	HCT116	viability after 9 days	GAGTTCTTCTGGTGACAACAAGG	RNF146	ENSG00000118518	0.8481355710065486	[362]	[269,98]	6	hSpCas9	negative selection	1982829
127287217	127287240	6	+	26627737	HCT116	viability after 9 days	GACAGTGTATCAGCACAGAGTGG	RNF146	ENSG00000118518	-0.6808006849131195	[894]	[257,62]	-5	hSpCas9	negative selection	1982830
127287602	127287625	6	+	26627737	HCT116	viability after 9 days	GAACTGATCGATCAGTAGCAGGG	RNF146	ENSG00000118518	1.8080924983926026	[327]	[404,228]	9	hSpCas9	negative selection	1982831
127287604	127287627	6	+	26627737	HCT116	viability after 9 days	ACTGATCGATCAGTAGCAGGGGG	RNF146	ENSG00000118518	0.40318647306616917	[173]	[61,60]	3	hSpCas9	negative selection	1982832
127286801	127286824	6	+	26627737	HCT116	viability after 12 days	GAGCTTCATGGCTTGGAAAGCGG	RNF146	ENSG00000118518	0.06839076096086849	[707]	[321,538,318]	0	hSpCas9	negative selection	2065142
127286832	127286855	6	+	26627737	HCT116	viability after 12 days	TTGTCGACAAGAAATTCCCGAGG	RNF146	ENSG00000118518	0.07896150492611076	[728]	[428,410,371]	0	hSpCas9	negative selection	2065143
127286873	127286896	6	-	26627737	HCT116	viability after 12 days	GAGTTCTTCTGGTGACAACAAGG	RNF146	ENSG00000118518	0.9429206835511994	[243]	[247,188,300]	7	hSpCas9	negative selection	2065144
127287217	127287240	6	+	26627737	HCT116	viability after 12 days	GACAGTGTATCAGCACAGAGTGG	RNF146	ENSG00000118518	0.34879795098701416	[301]	[129,173,307]	3	hSpCas9	negative selection	2065145
127287602	127287625	6	+	26627737	HCT116	viability after 12 days	GAACTGATCGATCAGTAGCAGGG	RNF146	ENSG00000118518	-0.12911870424392777	[361]	[136,251,137]	-1	hSpCas9	negative selection	2065146
127287604	127287627	6	+	26627737	HCT116	viability after 12 days	ACTGATCGATCAGTAGCAGGGGG	RNF146	ENSG00000118518	-0.3541881275119063	[169]	[73,56,77]	-4	hSpCas9	negative selection	2065147
127286801	127286824	6	+	26627737	HCT116	viability after 15 days	GAGCTTCATGGCTTGGAAAGCGG	RNF146	ENSG00000118518	0.26534672852363905	[707]	[427,481,547]	2	hSpCas9	negative selection	2147457
127286832	127286855	6	+	26627737	HCT116	viability after 15 days	TTGTCGACAAGAAATTCCCGAGG	RNF146	ENSG00000118518	0.5715933349065978	[728]	[767,548,567]	5	hSpCas9	negative selection	2147458
127286873	127286896	6	-	26627737	HCT116	viability after 15 days	GAGTTCTTCTGGTGACAACAAGG	RNF146	ENSG00000118518	0.793164350446687	[243]	[251,185,290]	7	hSpCas9	negative selection	2147459
127287217	127287240	6	+	26627737	HCT116	viability after 15 days	GACAGTGTATCAGCACAGAGTGG	RNF146	ENSG00000118518	0.47667508120443103	[301]	[163,257,291]	4	hSpCas9	negative selection	2147460
127287602	127287625	6	+	26627737	HCT116	viability after 15 days	GAACTGATCGATCAGTAGCAGGG	RNF146	ENSG00000118518	-0.13400082068158972	[361]	[176,212,176]	-1	hSpCas9	negative selection	2147461
127287604	127287627	6	+	26627737	HCT116	viability after 15 days	ACTGATCGATCAGTAGCAGGGGG	RNF146	ENSG00000118518	-0.24758689352771857	[169]	[11,130,94]	-3	hSpCas9	negative selection	2147462
127286801	127286824	6	+	26627737	HCT116	viability after 18 days	GAGCTTCATGGCTTGGAAAGCGG	RNF146	ENSG00000118518	0.02469007798754963	[707]	[364,311,370]	0	hSpCas9	negative selection	2229772
127286832	127286855	6	+	26627737	HCT116	viability after 18 days	TTGTCGACAAGAAATTCCCGAGG	RNF146	ENSG00000118518	0.38030079398459815	[728]	[421,526,420]	3	hSpCas9	negative selection	2229773
127286873	127286896	6	-	26627737	HCT116	viability after 18 days	GAGTTCTTCTGGTGACAACAAGG	RNF146	ENSG00000118518	0.6547690323112214	[243]	[139,102,325]	5	hSpCas9	negative selection	2229774
127287217	127287240	6	+	26627737	HCT116	viability after 18 days	GACAGTGTATCAGCACAGAGTGG	RNF146	ENSG00000118518	0.9886496766456584	[301]	[142,316,412]	7	hSpCas9	negative selection	2229775
127287602	127287625	6	+	26627737	HCT116	viability after 18 days	GAACTGATCGATCAGTAGCAGGG	RNF146	ENSG00000118518	0.22886093378751077	[361]	[161,190,265]	2	hSpCas9	negative selection	2229776
127287604	127287627	6	+	26627737	HCT116	viability after 18 days	ACTGATCGATCAGTAGCAGGGGG	RNF146	ENSG00000118518	0.21354797955795968	[169]	[0,115,170]	2	hSpCas9	negative selection	2229777
127286608	127286631	6	+	24336569	HL60	viability	TTTCTTAGGATGGCTGGCTGTGG	RNF146	ENSG00000118518	0.17552970304759793	[358]	[857]	1	hSpCas9	negative selection	2289905
127286648	127286671	6	+	24336569	HL60	viability	TAAACATGCTTCCTACAAACAGG	RNF146	ENSG00000118518	-0.34656097291958277	[279]	[465]	-3	hSpCas9	negative selection	2289906
127286659	127286682	6	-	24336569	HL60	viability	TCGTTCGCTTTCCTGTTTGTAGG	RNF146	ENSG00000118518	-1.0405338365740142	[416]	[428]	-7	hSpCas9	negative selection	2289907
127286684	127286707	6	-	24336569	HL60	viability	AGAAGGTGCAGTATTAGAACAGG	RNF146	ENSG00000118518	0.5918332991633942	[453]	[1447]	5	hSpCas9	negative selection	2289908
127286701	127286724	6	-	24336569	HL60	viability	CATTCAGGGACGGTTAAAGAAGG	RNF146	ENSG00000118518	0.647260115767041	[473]	[1570]	5	hSpCas9	negative selection	2289909
127286715	127286738	6	-	24336569	HL60	viability	GCAGACAAATGGCACATTCAGGG	RNF146	ENSG00000118518	0.5982766248443596	[539]	[1729]	5	hSpCas9	negative selection	2289910
127286726	127286749	6	-	24336569	HL60	viability	AACACATGTTTGCAGACAAATGG	RNF146	ENSG00000118518	0.013434541880165907	[830]	[1774]	0	hSpCas9	negative selection	2289911
127286752	127286775	6	-	24336569	HL60	viability	TGCTTACAGGGCAGACTGACTGG	RNF146	ENSG00000118518	-1.0510904515853776	[281]	[287]	-7	hSpCas9	negative selection	2289912
127286801	127286824	6	+	24336569	HL60	viability	GAGCTTCATGGCTTGGAAAGCGG	RNF146	ENSG00000118518	6.488391507702051	[0]	[189]	9	hSpCas9	negative selection	2289913
127286832	127286855	6	+	24336569	HL60	viability	TTGTCGACAAGAAATTCCCGAGG	RNF146	ENSG00000118518	-1.3475072563350283	[575]	[478]	-8	hSpCas9	negative selection	2289914
127286608	127286631	6	+	24336569	KBM7	viability	TTTCTTAGGATGGCTGGCTGTGG	RNF146	ENSG00000118518	0.7264804506246326	[270]	[1222]	6	hSpCas9	negative selection	2357082
127286648	127286671	6	+	24336569	KBM7	viability	TAAACATGCTTCCTACAAACAGG	RNF146	ENSG00000118518	0.9721609216952496	[133]	[716]	8	hSpCas9	negative selection	2357083
127286659	127286682	6	-	24336569	KBM7	viability	TCGTTCGCTTTCCTGTTTGTAGG	RNF146	ENSG00000118518	0.23089519009541792	[223]	[716]	2	hSpCas9	negative selection	2357084
127286684	127286707	6	-	24336569	KBM7	viability	AGAAGGTGCAGTATTAGAACAGG	RNF146	ENSG00000118518	0.20792229698842732	[458]	[1445]	2	hSpCas9	negative selection	2357085
127286701	127286724	6	-	24336569	KBM7	viability	CATTCAGGGACGGTTAAAGAAGG	RNF146	ENSG00000118518	-1.0624389959738028	[450]	[588]	-6	hSpCas9	negative selection	2357086
127286715	127286738	6	-	24336569	KBM7	viability	GCAGACAAATGGCACATTCAGGG	RNF146	ENSG00000118518	1.319276363228969	[288]	[1966]	9	hSpCas9	negative selection	2357087
127286726	127286749	6	-	24336569	KBM7	viability	AACACATGTTTGCAGACAAATGG	RNF146	ENSG00000118518	0.7613805180775128	[631]	[2921]	6	hSpCas9	negative selection	2357088
127286752	127286775	6	-	24336569	KBM7	viability	TGCTTACAGGGCAGACTGACTGG	RNF146	ENSG00000118518	-0.612137176339617	[217]	[388]	-5	hSpCas9	negative selection	2357089
127286801	127286824	6	+	24336569	KBM7	viability	GAGCTTCATGGCTTGGAAAGCGG	RNF146	ENSG00000118518	2.0118524220884146	[12]	[142]	9	hSpCas9	negative selection	2357090
127286832	127286855	6	+	24336569	KBM7	viability	TTGTCGACAAGAAATTCCCGAGG	RNF146	ENSG00000118518	-1.062085972884054	[221]	[289]	-6	hSpCas9	negative selection	2357091
127266702	127266725	6	+	25494202	A375	resistance to PLX-4720 (puromycin)	CCCCACAGGCAAGAGAGTACCGG	RNF146	ENSG00000118518	-1.6579598866742427	[80,49]	[3,4]	-8	dCas9-VP64	positive selection	2413868
127266671	127266694	6	-	25494202	A375	resistance to PLX-4720 (puromycin)	CTTCGCTGCTTGCATTCTTCTGG	RNF146	ENSG00000118518	-0.5708687343013125	[97,155]	[21,14]	-3	dCas9-VP64	positive selection	2413869
127266723	127266746	6	+	25494202	A375	resistance to PLX-4720 (puromycin)	GGCAGACAGCGGCGCGAGACAGG	RNF146	ENSG00000118518	3.507923087005672	[27,179]	[499,11]	9	dCas9-VP64	positive selection	2413870
127266616	127266639	6	+	25494202	A375	resistance to PLX-4720 (puromycin)	TGCACTCTTTCAGAGCCTCTGGG	RNF146	ENSG00000118518	-0.8458619942585931	[254,211]	[29,25]	-5	dCas9-VP64	positive selection	2413871
127266592	127266615	6	-	25494202	A375	resistance to PLX-4720 (puromycin)	TTCCAACAGAAAGAGATTTGGGG	RNF146	ENSG00000118518	0.08340319027117638	[24,72]	[2,19]	0	dCas9-VP64	positive selection	2413872
127266702	127266725	6	+	25494202	A375	resistance to PLX-4720 (zeocin)	CCCCACAGGCAAGAGAGTACCGG	RNF146	ENSG00000118518	-0.30350550205423027	[184,42]	[47,12]	-3	dCas9-VP64	positive selection	2509123
127266671	127266694	6	-	25494202	A375	resistance to PLX-4720 (zeocin)	CTTCGCTGCTTGCATTCTTCTGG	RNF146	ENSG00000118518	3.1737384307373278	[225,60]	[63,770]	9	dCas9-VP64	positive selection	2509124
127266723	127266746	6	+	25494202	A375	resistance to PLX-4720 (zeocin)	GGCAGACAGCGGCGCGAGACAGG	RNF146	ENSG00000118518	-0.23059735875675036	[361,60]	[102,17]	-2	dCas9-VP64	positive selection	2509125
127266616	127266639	6	+	25494202	A375	resistance to PLX-4720 (zeocin)	TGCACTCTTTCAGAGCCTCTGGG	RNF146	ENSG00000118518	-0.4438765430810709	[256,152]	[49,48]	-4	dCas9-VP64	positive selection	2509126
127266592	127266615	6	-	25494202	A375	resistance to PLX-4720 (zeocin)	TTCCAACAGAAAGAGATTTGGGG	RNF146	ENSG00000118518	-1.2486277301531	[128,39]	[13,8]	-9	dCas9-VP64	positive selection	2509127
127286711	127286734	6	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	ACAAATGGCACATTCAGGGACGG	RNF146	ENSG00000118518	0.3563416340852843	[3,2]	[5,2]	7	hSpCas9	positive selection	3017193
127287122	127287145	6	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	ATAATAGATATACCAAAGAAGGG	RNF146	ENSG00000118518	0.6603397761733781	[2,1]	[3,3]	9	hSpCas9	positive selection	3017194
127286869	127286892	6	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TCTTCTGGTGACAACAAGGTTGG	RNF146	ENSG00000118518	0.15616445149690683	[4,4]	[3,4]	3	hSpCas9	positive selection	3017195
127286833	127286856	6	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TTGTCGACAAGAAATTCCCGAGG	RNF146	ENSG00000118518	0.011690863814236278	[3,3]	[3,2]	0	hSpCas9	positive selection	3017196
127286711	127286734	6	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	ACAAATGGCACATTCAGGGACGG	RNF146	ENSG00000118518	0.24154161222641846	[3,3]	[4,2]	4	hSpCas9	positive selection	3085051
127287122	127287145	6	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	ATAATAGATATACCAAAGAAGGG	RNF146	ENSG00000118518	-0.8046828801956675	[2,2]	[1,0]	-9	hSpCas9	positive selection	3085052
127286869	127286892	6	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TCTTCTGGTGACAACAAGGTTGG	RNF146	ENSG00000118518	0.29564416511942576	[4,4]	[4,3]	5	hSpCas9	positive selection	3085053
127286833	127286856	6	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TTGTCGACAAGAAATTCCCGAGG	RNF146	ENSG00000118518	-0.06177070682366487	[3,3]	[2,1]	-1	hSpCas9	positive selection	3085054
127286765	127286788		-	24336571	A375	resistance to PLX after 7 days	ATAGCAGAAAACGTGCTTACAGG	RNF146	ENSG00000118518	0.017982650762009555	[22,25]	[22,26]	0	hSpCas9	positive selection	3141254
127286967	127286990		+	24336571	A375	resistance to PLX after 7 days	TGAGCGCACTAGTAGAGAGCTGG	RNF146	ENSG00000118518	0.53740541671133	[12,10]	[14,20]	9	hSpCas9	positive selection	3141255
127286765	127286788		-	24336571	A375	resistance to PLX after 14 days	ATAGCAGAAAACGTGCTTACAGG	RNF146	ENSG00000118518	-1.042804535122521	[34,37]	[6,8]	-9	hSpCas9	positive selection	3199047
127286967	127286990		+	24336571	A375	resistance to PLX after 14 days	TGAGCGCACTAGTAGAGAGCTGG	RNF146	ENSG00000118518	1.9398246486943544	[18,13]	[37,22]	9	hSpCas9	positive selection	3199048
127286765	127286788		-	24336571	A375	viability after 7 days	ATAGCAGAAAACGTGCTTACAGG	RNF146	ENSG00000118518	0.6418054811746144	[16]	[22,25]	8	hSpCas9	negative selection	3256840
127286967	127286990		+	24336571	A375	viability after 7 days	TGAGCGCACTAGTAGAGAGCTGG	RNF146	ENSG00000118518	-0.09388027160371146	[13]	[12,10]	-1	hSpCas9	negative selection	3256841
127286765	127286788		-	24336571	A375	viability after 14 days	ATAGCAGAAAACGTGCTTACAGG	RNF146	ENSG00000118518	1.2094736804483326	[16]	[34,37]	9	hSpCas9	negative selection	3314633
127286967	127286990		+	24336571	A375	viability after 14 days	TGAGCGCACTAGTAGAGAGCTGG	RNF146	ENSG00000118518	0.3580488363658415	[13]	[18,13]	4	hSpCas9	negative selection	3314634
127286765	127286788	6	-	27383988	293T	resistance to West Nile virus (flavivirus)	ATAGCAGAAAACGTGCTTACAGG	RNF146	ENSG00000118518	2.7978945928085377	[21,21]	[0,0]	8	hSpCas9	positive selection	3390103
127286832	127286855	6	+	27383988	293T	resistance to West Nile virus (flavivirus)	TTGTCGACAAGAAATTCCCGAGG	RNF146	ENSG00000118518	0.5158592250446882	[106,106]	[0,0]	2	hSpCas9	positive selection	3390104
127286701	127286724	6	-	27383988	293T	resistance to West Nile virus (flavivirus)	CATTCAGGGACGGTTAAAGAAGG	RNF146	ENSG00000118518	1.148801754667666	[68,68]	[0,0]	5	hSpCas9	positive selection	3390105
127286711	127286734	6	-	26780180	HT29	viability (Avana library 4 designs)	ACAAATGGCACATTCAGGGACGG	RNF146	ENSG00000118518	1.53121257921548	[]	[]	6	hSpCas9	negative selection	3455564
127287121	127287144	6	+	26780180	HT29	viability (Avana library 4 designs)	ATAATAGATATACCAAAGAAGGG	RNF146	ENSG00000118518	1.41758051381647	[]	[]	5	hSpCas9	negative selection	3455565
127286869	127286892	6	-	26780180	HT29	viability (Avana library 4 designs)	TCTTCTGGTGACAACAAGGTTGG	RNF146	ENSG00000118518	0.679865072577964	[]	[]	2	hSpCas9	negative selection	3455566
127286832	127286855	6	+	26780180	HT29	viability (Avana library 4 designs)	TTGTCGACAAGAAATTCCCGAGG	RNF146	ENSG00000118518	0.888080454027446	[]	[]	3	hSpCas9	negative selection	3455567
127286832	127286855	6	+	26780180	A375	viability (Avana lentiCRISPRv2)	TTGTCGACAAGAAATTCCCGAGG	RNF146	ENSG00000118518	1.57099208060312	[]	[]	2	hSpCas9	negative selection	3553616
127286711	127286734	6	-	26780180	A375	viability (Avana lentiCRISPRv2)	ACAAATGGCACATTCAGGGACGG	RNF146	ENSG00000118518	1.19830406315626	[]	[]	1	hSpCas9	negative selection	3553617
127286869	127286892	6	-	26780180	A375	viability (Avana lentiCRISPRv2)	TCTTCTGGTGACAACAAGGTTGG	RNF146	ENSG00000118518	1.35704213127387	[]	[]	2	hSpCas9	negative selection	3553618
127287121	127287144	6	+	26780180	A375	viability (Avana lentiCRISPRv2)	ATAATAGATATACCAAAGAAGGG	RNF146	ENSG00000118518	-22.1528868941363	[]	[]	-9	hSpCas9	negative selection	3553619
127286936	127286959	6	+	26780180	A375	viability (Avana lentiCRISPRv2)	ATGAAGGAAGAAATGGGTGGTGG	RNF146	ENSG00000118518	3.5227793120411	[]	[]	5	hSpCas9	negative selection	3553620
127286933	127286956	6	+	26780180	A375	viability (Avana lentiCRISPRv2)	ATTATGAAGGAAGAAATGGGTGG	RNF146	ENSG00000118518	-5.81182218583692	[]	[]	-6	hSpCas9	negative selection	3553621
127286832	127286855	6	+	26780180	A375	viability (Avana lentiGuide)	TTGTCGACAAGAAATTCCCGAGG	RNF146	ENSG00000118518	-3.56387910201168	[]	[]	-6	hSpCas9	negative selection	3662275
127286711	127286734	6	-	26780180	A375	viability (Avana lentiGuide)	ACAAATGGCACATTCAGGGACGG	RNF146	ENSG00000118518	-2.00188687667035	[]	[]	-3	hSpCas9	negative selection	3662276
127286869	127286892	6	-	26780180	A375	viability (Avana lentiGuide)	TCTTCTGGTGACAACAAGGTTGG	RNF146	ENSG00000118518	-3.58716839004318	[]	[]	-6	hSpCas9	negative selection	3662277
127287121	127287144	6	+	26780180	A375	viability (Avana lentiGuide)	ATAATAGATATACCAAAGAAGGG	RNF146	ENSG00000118518	-10.8702899758104	[]	[]	-9	hSpCas9	negative selection	3662278
127286936	127286959	6	+	26780180	A375	viability (Avana lentiGuide)	ATGAAGGAAGAAATGGGTGGTGG	RNF146	ENSG00000118518	-3.30959699757959	[]	[]	-6	hSpCas9	negative selection	3662279
127286933	127286956	6	+	26780180	A375	viability (Avana lentiGuide)	ATTATGAAGGAAGAAATGGGTGG	RNF146	ENSG00000118518	-3.7633905664877	[]	[]	-6	hSpCas9	negative selection	3662280
127286832	127286855	6	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TTGTCGACAAGAAATTCCCGAGG	RNF146	ENSG00000118518	-0.044503369712314916	[5]	[5,4]	0	hSpCas9	positive selection	3770882
127286711	127286734	6	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ACAAATGGCACATTCAGGGACGG	RNF146	ENSG00000118518	0.16322176643061842	[5]	[6,4]	4	hSpCas9	positive selection	3770883
127286869	127286892	6	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TCTTCTGGTGACAACAAGGTTGG	RNF146	ENSG00000118518	0.20903085748385836	[5]	[7,5]	6	hSpCas9	positive selection	3770884
127287121	127287144	6	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ATAATAGATATACCAAAGAAGGG	RNF146	ENSG00000118518	-0.7509609100902697	[8]	[4,4]	-8	hSpCas9	positive selection	3770885
127286936	127286959	6	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ATGAAGGAAGAAATGGGTGGTGG	RNF146	ENSG00000118518	0.3736700839305023	[5]	[7,6]	9	hSpCas9	positive selection	3770886
127286933	127286956	6	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ATTATGAAGGAAGAAATGGGTGG	RNF146	ENSG00000118518	-0.12488468408264175	[7]	[6,6]	-2	hSpCas9	positive selection	3770887
127286832	127286855	6	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TTGTCGACAAGAAATTCCCGAGG	RNF146	ENSG00000118518	0.30775444495130916	[5]	[5,6]	8	hSpCas9	positive selection	3879489
127286711	127286734	6	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ACAAATGGCACATTCAGGGACGG	RNF146	ENSG00000118518	0.10604855769515467	[5]	[4,5]	2	hSpCas9	positive selection	3879490
127286869	127286892	6	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TCTTCTGGTGACAACAAGGTTGG	RNF146	ENSG00000118518	0.4617623215889769	[6]	[7,7]	9	hSpCas9	positive selection	3879491
127287121	127287144	6	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ATAATAGATATACCAAAGAAGGG	RNF146	ENSG00000118518	0.6445539053696945	[3]	[5,3]	9	hSpCas9	positive selection	3879492
127286936	127286959	6	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ATGAAGGAAGAAATGGGTGGTGG	RNF146	ENSG00000118518	0.3982658580580322	[5]	[6,6]	9	hSpCas9	positive selection	3879493
127286933	127286956	6	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ATTATGAAGGAAGAAATGGGTGG	RNF146	ENSG00000118518	0.42117611513996667	[6]	[7,7]	9	hSpCas9	positive selection	3879494
127287276	127287299	6	-	26780180	A375	viability	ACTGACCATCTACTGATGTTAGG	RNF146	ENSG00000118518	1.15436422565226	[]	[]	6	hSpCas9	negative selection	3989606
127286765	127286788	6	-	26780180	A375	viability	ATAGCAGAAAACGTGCTTACAGG	RNF146	ENSG00000118518	0.787009318172824	[]	[]	3	hSpCas9	negative selection	3989607
127286701	127286724	6	-	26780180	A375	viability	CATTCAGGGACGGTTAAAGAAGG	RNF146	ENSG00000118518	0.572692330670906	[]	[]	1	hSpCas9	negative selection	3989608
127287661	127287684	6	-	26780180	A375	viability	GTTACTGTGCACTGTCCATCAGG	RNF146	ENSG00000118518	0.441315891522111	[]	[]	1	hSpCas9	negative selection	3989609
127286967	127286990	6	+	26780180	A375	viability	TGAGCGCACTAGTAGAGAGCTGG	RNF146	ENSG00000118518	0.695159325197701	[]	[]	2	hSpCas9	negative selection	3989610
127286832	127286855	6	+	26780180	A375	viability	TTGTCGACAAGAAATTCCCGAGG	RNF146	ENSG00000118518	1.28144492639911	[]	[]	7	hSpCas9	negative selection	3989611
127287276	127287299	6	-	26780180	HT29	viability (GeCKOv2 library)	ACTGACCATCTACTGATGTTAGG	RNF146	ENSG00000118518	1.25579423595717	[]	[]	6	hSpCas9	negative selection	4097572
127286765	127286788	6	-	26780180	HT29	viability (GeCKOv2 library)	ATAGCAGAAAACGTGCTTACAGG	RNF146	ENSG00000118518	1.14030502603693	[]	[]	5	hSpCas9	negative selection	4097573
127286701	127286724	6	-	26780180	HT29	viability (GeCKOv2 library)	CATTCAGGGACGGTTAAAGAAGG	RNF146	ENSG00000118518	0.964767082166147	[]	[]	4	hSpCas9	negative selection	4097574
127287661	127287684	6	-	26780180	HT29	viability (GeCKOv2 library)	GTTACTGTGCACTGTCCATCAGG	RNF146	ENSG00000118518	0.266505893581688	[]	[]	0	hSpCas9	negative selection	4097575
127286967	127286990	6	+	26780180	HT29	viability (GeCKOv2 library)	TGAGCGCACTAGTAGAGAGCTGG	RNF146	ENSG00000118518	1.02768539658398	[]	[]	5	hSpCas9	negative selection	4097576
127286832	127286855	6	+	26780180	HT29	viability (GeCKOv2 library)	TTGTCGACAAGAAATTCCCGAGG	RNF146	ENSG00000118518	1.28660127084527	[]	[]	6	hSpCas9	negative selection	4097577
127286765	127286788	6	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	ATAGCAGAAAACGTGCTTACAGG	RNF146	ENSG00000118518	-0.13665341004791587	[4]	[1,2]	-3	hSpCas9	positive selection	4166778
127286967	127286990	6	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TGAGCGCACTAGTAGAGAGCTGG	RNF146	ENSG00000118518	0.5787676292942712	[3]	[2,4]	9	hSpCas9	positive selection	4166779
127286765	127286788	6	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	ATAGCAGAAAACGTGCTTACAGG	RNF146	ENSG00000118518	-0.07899133724337001	[4]	[0,3,2,0]	-1	hSpCas9	positive selection	4230800
127286967	127286990	6	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TGAGCGCACTAGTAGAGAGCTGG	RNF146	ENSG00000118518	1.0411794056942127	[3]	[0,3,2,4]	7	hSpCas9	positive selection	4230801
127287661	127287684	6	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GTTACTGTGCACTGTCCATCAGG	RNF146	ENSG00000118518	0.484526255451291	[0]	[2,0]	8	hSpCas9	positive selection	4295166
127287276	127287299	6	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ACTGACCATCTACTGATGTTAGG	RNF146	ENSG00000118518	0.3526385240413118	[2]	[3,2]	7	hSpCas9	positive selection	4295167
127286967	127286990	6	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TGAGCGCACTAGTAGAGAGCTGG	RNF146	ENSG00000118518	-0.23506575038120536	[1]	[1,0]	-5	hSpCas9	positive selection	4295168
127286765	127286788	6	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ATAGCAGAAAACGTGCTTACAGG	RNF146	ENSG00000118518	-0.08093165932677293	[1]	[1,0]	-1	hSpCas9	positive selection	4359420
127286832	127286855	6	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TTGTCGACAAGAAATTCCCGAGG	RNF146	ENSG00000118518	0.25516351666063014	[2]	[3,2]	5	hSpCas9	positive selection	4359421
127286701	127286724	6	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CATTCAGGGACGGTTAAAGAAGG	RNF146	ENSG00000118518	0.09722751826987269	[2]	[2,0]	2	hSpCas9	positive selection	4359422
127286701	127286723	6	-	27760321	OCIAML3	viability	ATTCAGGGACGGTTAAAGAAGG	RNF146	ENSG00000118518	1.0815599486972325	[67,65]	[78,152]	9	hSpCas9	negative selection	4435093
127286833	127286855	6	+	27760321	OCIAML3	viability	TGTCGACAAGAAATTCCCGAGG	RNF146	ENSG00000118518	0.25176761712043305	[361,287]	[315,280]	3	hSpCas9	negative selection	4435094
127286878	127286900	6	+	27760321	OCIAML3	viability	TTGTCACCAGAAGAACTCAAGG	RNF146	ENSG00000118518	0.70423709530398	[145,101]	[104,222]	8	hSpCas9	negative selection	4435095
127287131	127287153	6	+	27760321	OCIAML3	viability	TACCAAAGAAGGGAGTAGCTGG	RNF146	ENSG00000118518	0.47038669091431673	[294,250]	[240,364]	5	hSpCas9	negative selection	4435096
127287253	127287275	6	-	27760321	OCIAML3	viability	GCCTTACAGAAGACACTAGGGG	RNF146	ENSG00000118518	0.349869932207314	[0,0]	[0,0]	4	hSpCas9	negative selection	4435097
127286701	127286723	6	-	27760321	OCIAML2	viability	ATTCAGGGACGGTTAAAGAAGG	RNF146	ENSG00000118518	0.51303848872104	[67,65]	[86,64]	7	hSpCas9	negative selection	4518556
127286833	127286855	6	+	27760321	OCIAML2	viability	TGTCGACAAGAAATTCCCGAGG	RNF146	ENSG00000118518	0.05329601305268844	[361,287]	[227,327]	0	hSpCas9	negative selection	4518557
127286878	127286900	6	+	27760321	OCIAML2	viability	TTGTCACCAGAAGAACTCAAGG	RNF146	ENSG00000118518	0.5147749590556603	[145,101]	[142,139]	7	hSpCas9	negative selection	4518558
127287131	127287153	6	+	27760321	OCIAML2	viability	TACCAAAGAAGGGAGTAGCTGG	RNF146	ENSG00000118518	-0.009298551769489571	[294,250]	[241,187]	0	hSpCas9	negative selection	4518559
127287253	127287275	6	-	27760321	OCIAML2	viability	GCCTTACAGAAGACACTAGGGG	RNF146	ENSG00000118518	0.3011245669422653	[0,0]	[0,0]	4	hSpCas9	negative selection	4518560
127286701	127286723	6	-	27760321	MV411	viability	ATTCAGGGACGGTTAAAGAAGG	RNF146	ENSG00000118518	-0.9081358157207076	[67,65]	[33,7]	-6	hSpCas9	negative selection	4602019
127286833	127286855	6	+	27760321	MV411	viability	TGTCGACAAGAAATTCCCGAGG	RNF146	ENSG00000118518	1.24867383515546	[361,287]	[669,260]	8	hSpCas9	negative selection	4602020
127286878	127286900	6	+	27760321	MV411	viability	TTGTCACCAGAAGAACTCAAGG	RNF146	ENSG00000118518	-0.9538890551639068	[145,101]	[0,102]	-6	hSpCas9	negative selection	4602021
127287131	127287153	6	+	27760321	MV411	viability	TACCAAAGAAGGGAGTAGCTGG	RNF146	ENSG00000118518	0.5863958452201721	[294,250]	[265,274]	4	hSpCas9	negative selection	4602022
127287253	127287275	6	-	27760321	MV411	viability	GCCTTACAGAAGACACTAGGGG	RNF146	ENSG00000118518	0.5949485011219959	[0,0]	[0,0]	4	hSpCas9	negative selection	4602023
127286701	127286723	6	-	27760321	HL60	viability	ATTCAGGGACGGTTAAAGAAGG	RNF146	ENSG00000118518	1.0833844800585224	[67,65]	[172,55]	9	hSpCas9	negative selection	4685482
127286833	127286855	6	+	27760321	HL60	viability	TGTCGACAAGAAATTCCCGAGG	RNF146	ENSG00000118518	0.45819577698433817	[361,287]	[329,396]	5	hSpCas9	negative selection	4685483
127286878	127286900	6	+	27760321	HL60	viability	TTGTCACCAGAAGAACTCAAGG	RNF146	ENSG00000118518	1.2312908798359645	[145,101]	[255,212]	9	hSpCas9	negative selection	4685484
127287131	127287153	6	+	27760321	HL60	viability	TACCAAAGAAGGGAGTAGCTGG	RNF146	ENSG00000118518	0.5801039070702874	[294,250]	[357,304]	7	hSpCas9	negative selection	4685485
127287253	127287275	6	-	27760321	HL60	viability	GCCTTACAGAAGACACTAGGGG	RNF146	ENSG00000118518	0.2870783393278593	[0,0]	[0,0]	3	hSpCas9	negative selection	4685486
127286701	127286723	6	-	27760321	HT1080	viability	ATTCAGGGACGGTTAAAGAAGG	RNF146	ENSG00000118518	3.114288474311384	[65,51]	[111,303]	9	hSpCas9	negative selection	4768945
127286833	127286855	6	+	27760321	HT1080	viability	TGTCGACAAGAAATTCCCGAGG	RNF146	ENSG00000118518	3.0128150592341747	[287,224]	[651,1013]	9	hSpCas9	negative selection	4768946
127286878	127286900	6	+	27760321	HT1080	viability	TTGTCACCAGAAGAACTCAAGG	RNF146	ENSG00000118518	1.9621970141185292	[101,79]	[252,18]	9	hSpCas9	negative selection	4768947
127287131	127287153	6	+	27760321	HT1080	viability	TACCAAAGAAGGGAGTAGCTGG	RNF146	ENSG00000118518	2.6774335426994393	[250,195]	[402,751]	9	hSpCas9	negative selection	4768948
127287253	127287275	6	-	27760321	HT1080	viability	GCCTTACAGAAGACACTAGGGG	RNF146	ENSG00000118518	1.3056276939190559	[0,0]	[0,0]	7	hSpCas9	negative selection	4768949
127286701	127286723	6	-	27760321	HT29	viability after 7 days	ATTCAGGGACGGTTAAAGAAGG	RNF146	ENSG00000118518	-0.46481697730592897	[65,51]	[72,87,7]	-6	hSpCas9	negative selection	4852408
127286833	127286855	6	+	27760321	HT29	viability after 7 days	TGTCGACAAGAAATTCCCGAGG	RNF146	ENSG00000118518	0.07154718039917685	[287,224]	[351,436,253]	1	hSpCas9	negative selection	4852409
127286878	127286900	6	+	27760321	HT29	viability after 7 days	TTGTCACCAGAAGAACTCAAGG	RNF146	ENSG00000118518	0.5311751239751685	[101,79]	[156,197,150]	7	hSpCas9	negative selection	4852410
127287131	127287153	6	+	27760321	HT29	viability after 7 days	TACCAAAGAAGGGAGTAGCTGG	RNF146	ENSG00000118518	0.47508906338432494	[250,195]	[340,435,411]	7	hSpCas9	negative selection	4852411
127287253	127287275	6	-	27760321	HT29	viability after 7 days	GCCTTACAGAAGACACTAGGGG	RNF146	ENSG00000118518	-0.3840325596302083	[0,0]	[0,0,0]	-5	hSpCas9	negative selection	4852412
127286701	127286723	6	-	27760321	HT29	viability after 25 days	ATTCAGGGACGGTTAAAGAAGG	RNF146	ENSG00000118518	0.8638033921358987	[65,51]	[176,53,134]	8	hSpCas9	negative selection	4935871
127286833	127286855	6	+	27760321	HT29	viability after 25 days	TGTCGACAAGAAATTCCCGAGG	RNF146	ENSG00000118518	0.17914579481556775	[287,224]	[264,414,317]	1	hSpCas9	negative selection	4935872
127286878	127286900	6	+	27760321	HT29	viability after 25 days	TTGTCACCAGAAGAACTCAAGG	RNF146	ENSG00000118518	0.8948192704700171	[101,79]	[217,144,217]	9	hSpCas9	negative selection	4935873
127287131	127287153	6	+	27760321	HT29	viability after 25 days	TACCAAAGAAGGGAGTAGCTGG	RNF146	ENSG00000118518	-0.00441598283861222	[250,195]	[229,358,166]	0	hSpCas9	negative selection	4935874
127287253	127287275	6	-	27760321	HT29	viability after 25 days	GCCTTACAGAAGACACTAGGGG	RNF146	ENSG00000118518	-0.21405457092746794	[0,0]	[0,0,0]	-2	hSpCas9	negative selection	4935875
127286701	127286723	6	-	27760321	HT29	viability after 22 days	ATTCAGGGACGGTTAAAGAAGG	RNF146	ENSG00000118518	0.04102974746887966	[65,51]	[70,29,109]	0	hSpCas9	negative selection	5019334
127286833	127286855	6	+	27760321	HT29	viability after 22 days	TGTCGACAAGAAATTCCCGAGG	RNF146	ENSG00000118518	0.14394596918864555	[287,224]	[174,493,317]	1	hSpCas9	negative selection	5019335
127286878	127286900	6	+	27760321	HT29	viability after 22 days	TTGTCACCAGAAGAACTCAAGG	RNF146	ENSG00000118518	0.5060449257405821	[101,79]	[115,103,229]	5	hSpCas9	negative selection	5019336
127287131	127287153	6	+	27760321	HT29	viability after 22 days	TACCAAAGAAGGGAGTAGCTGG	RNF146	ENSG00000118518	0.22708239939265173	[250,195]	[99,379,433]	2	hSpCas9	negative selection	5019337
127287253	127287275	6	-	27760321	HT29	viability after 22 days	GCCTTACAGAAGACACTAGGGG	RNF146	ENSG00000118518	-0.23137320278672746	[0,0]	[0,0,0]	-2	hSpCas9	negative selection	5019338
127286701	127286723	6	-	27760321	HT29	viability after 19 days	ATTCAGGGACGGTTAAAGAAGG	RNF146	ENSG00000118518	0.052625916922763416	[65,51]	[158,7,52]	0	hSpCas9	negative selection	5102797
127286833	127286855	6	+	27760321	HT29	viability after 19 days	TGTCGACAAGAAATTCCCGAGG	RNF146	ENSG00000118518	0.37164034332690604	[287,224]	[504,438,213]	3	hSpCas9	negative selection	5102798
127286878	127286900	6	+	27760321	HT29	viability after 19 days	TTGTCACCAGAAGAACTCAAGG	RNF146	ENSG00000118518	0.7337443813199527	[101,79]	[169,150,196]	7	hSpCas9	negative selection	5102799
127287131	127287153	6	+	27760321	HT29	viability after 19 days	TACCAAAGAAGGGAGTAGCTGG	RNF146	ENSG00000118518	0.8007668360642948	[250,195]	[217,787,310]	7	hSpCas9	negative selection	5102800
127287253	127287275	6	-	27760321	HT29	viability after 19 days	GCCTTACAGAAGACACTAGGGG	RNF146	ENSG00000118518	-0.21553315036351428	[0,0]	[0,0,0]	-2	hSpCas9	negative selection	5102801
127286701	127286723	6	-	27760321	HT29	viability after 16 days	ATTCAGGGACGGTTAAAGAAGG	RNF146	ENSG00000118518	0.6534003069321979	[65,51]	[165,84,66]	7	hSpCas9	negative selection	5186260
127286833	127286855	6	+	27760321	HT29	viability after 16 days	TGTCGACAAGAAATTCCCGAGG	RNF146	ENSG00000118518	0.3202670099767375	[287,224]	[212,403,442]	3	hSpCas9	negative selection	5186261
127286878	127286900	6	+	27760321	HT29	viability after 16 days	TTGTCACCAGAAGAACTCAAGG	RNF146	ENSG00000118518	0.9762263148141255	[101,79]	[150,137,308]	9	hSpCas9	negative selection	5186262
127287131	127287153	6	+	27760321	HT29	viability after 16 days	TACCAAAGAAGGGAGTAGCTGG	RNF146	ENSG00000118518	0.17159588605503873	[250,195]	[222,294,320]	1	hSpCas9	negative selection	5186263
127287253	127287275	6	-	27760321	HT29	viability after 16 days	GCCTTACAGAAGACACTAGGGG	RNF146	ENSG00000118518	-0.1840686979425925	[0,0]	[0,0,0]	-2	hSpCas9	negative selection	5186264
127286701	127286723	6	-	27760321	HT29	viability after 13 days	ATTCAGGGACGGTTAAAGAAGG	RNF146	ENSG00000118518	0.28929945012605884	[65,51]	[102,63,83]	3	hSpCas9	negative selection	5269723
127286833	127286855	6	+	27760321	HT29	viability after 13 days	TGTCGACAAGAAATTCCCGAGG	RNF146	ENSG00000118518	-0.13285016311119996	[287,224]	[274,247,289]	-1	hSpCas9	negative selection	5269724
127286878	127286900	6	+	27760321	HT29	viability after 13 days	TTGTCACCAGAAGAACTCAAGG	RNF146	ENSG00000118518	0.4358853878893769	[101,79]	[177,99,149]	5	hSpCas9	negative selection	5269725
127287131	127287153	6	+	27760321	HT29	viability after 13 days	TACCAAAGAAGGGAGTAGCTGG	RNF146	ENSG00000118518	-0.2661178105748415	[250,195]	[198,285,164]	-3	hSpCas9	negative selection	5269726
127287253	127287275	6	-	27760321	HT29	viability after 13 days	GCCTTACAGAAGACACTAGGGG	RNF146	ENSG00000118518	-0.23635609738673047	[0,0]	[0,0,0]	-3	hSpCas9	negative selection	5269727
127286701	127286723	6	-	27760321	HT29	viability after 10 days	ATTCAGGGACGGTTAAAGAAGG	RNF146	ENSG00000118518	0.3286260855191685	[65,51]	[199,50,26]	4	hSpCas9	negative selection	5353186
127286833	127286855	6	+	27760321	HT29	viability after 10 days	TGTCGACAAGAAATTCCCGAGG	RNF146	ENSG00000118518	0.6297874475618597	[287,224]	[550,437,495]	8	hSpCas9	negative selection	5353187
127286878	127286900	6	+	27760321	HT29	viability after 10 days	TTGTCACCAGAAGAACTCAAGG	RNF146	ENSG00000118518	-0.004697650741567694	[101,79]	[125,130,83]	0	hSpCas9	negative selection	5353188
127287131	127287153	6	+	27760321	HT29	viability after 10 days	TACCAAAGAAGGGAGTAGCTGG	RNF146	ENSG00000118518	-0.24583788998408207	[250,195]	[319,257,130]	-3	hSpCas9	negative selection	5353189
127287253	127287275	6	-	27760321	HT29	viability after 10 days	GCCTTACAGAAGACACTAGGGG	RNF146	ENSG00000118518	-0.34236740454707437	[0,0]	[0,0,0]	-4	hSpCas9	negative selection	5353190
127286701	127286723	6	-	27760321	MOLM13	viability	ATTCAGGGACGGTTAAAGAAGG	RNF146	ENSG00000118518	-2.2393431727555546	[67,65]	[0,13]	-8	hSpCas9	negative selection	5436649
127286833	127286855	6	+	27760321	MOLM13	viability	TGTCGACAAGAAATTCCCGAGG	RNF146	ENSG00000118518	-0.04950207558273656	[361,287]	[93,245]	0	hSpCas9	negative selection	5436650
127286878	127286900	6	+	27760321	MOLM13	viability	TTGTCACCAGAAGAACTCAAGG	RNF146	ENSG00000118518	-0.28511283033131885	[145,101]	[32,76]	-2	hSpCas9	negative selection	5436651
127287131	127287153	6	+	27760321	MOLM13	viability	TACCAAAGAAGGGAGTAGCTGG	RNF146	ENSG00000118518	-0.4024300545289906	[294,250]	[167,71]	-3	hSpCas9	negative selection	5436652
127287253	127287275	6	-	27760321	MOLM13	viability	GCCTTACAGAAGACACTAGGGG	RNF146	ENSG00000118518	0.8210053139495912	[0,0]	[0,0]	6	hSpCas9	negative selection	5436653
127267085	127267108	6	+	27661255	K562	viability	GTCAGGGGCCGGTACGTAGATGG	RNF146	ENSG00000118518	-0.1707991618563291	[1038,1092]	[873,654]	-5	dCas9-KRAB	negative selection	5507849
127267275	127267298	6	+	27661255	K562	viability	GGTCTCGGTCCGGGTGCGAGGGG	RNF146	ENSG00000118518	0.15064779282297408	[536,582]	[531,464]	5	dCas9-KRAB	negative selection	5507850
127267323	127267346	6	-	27661255	K562	viability	GAAGCGGGCTCAGGCGGAAGAGG	RNF146	ENSG00000118518	-0.7255476016417434	[785,986]	[466,391]	-8	dCas9-KRAB	negative selection	5507851
127287661	127287684	6	-	27260156	BXPC3	viability	GTTACTGTGCACTGTCCATCAGG	RNF146	ENSG00000118518	0.443837913878808	[59]	[80,57,97,108]	8	hSpCas9	negative selection	5567626
127287276	127287299	6	-	27260156	BXPC3	viability	ACTGACCATCTACTGATGTTAGG	RNF146	ENSG00000118518	-0.12479625001022789	[442]	[471,327,403,501]	-3	hSpCas9	negative selection	5567627
127286967	127286990	6	+	27260156	BXPC3	viability	TGAGCGCACTAGTAGAGAGCTGG	RNF146	ENSG00000118518	-0.3937927019311256	[139]	[81,118,127,119]	-7	hSpCas9	negative selection	5567628
127286765	127286788	6	-	27260156	BXPC3	viability	ATAGCAGAAAACGTGCTTACAGG	RNF146	ENSG00000118518	-0.20530083515527475	[139]	[124,81,182,119]	-5	hSpCas9	negative selection	5631880
127286832	127286855	6	+	27260156	BXPC3	viability	TTGTCGACAAGAAATTCCCGAGG	RNF146	ENSG00000118518	-0.5067218633774462	[443]	[258,313,318,433]	-8	hSpCas9	negative selection	5631881
127286701	127286724	6	-	27260156	BXPC3	viability	CATTCAGGGACGGTTAAAGAAGG	RNF146	ENSG00000118518	-0.006058723872717886	[212]	[254,214,211,196]	0	hSpCas9	negative selection	5631882
127287661	127287684	6	-	27260156	A673	viability	GTTACTGTGCACTGTCCATCAGG	RNF146	ENSG00000118518	0.7219344000838595	[59]	[106,139,154,67]	9	hSpCas9	negative selection	5688877
127287276	127287299	6	-	27260156	A673	viability	ACTGACCATCTACTGATGTTAGG	RNF146	ENSG00000118518	0.24585843175725408	[442]	[672,503,547,815]	6	hSpCas9	negative selection	5688878
127286967	127286990	6	+	27260156	A673	viability	TGAGCGCACTAGTAGAGAGCTGG	RNF146	ENSG00000118518	-0.31376383757403836	[139]	[120,114,113,192]	-6	hSpCas9	negative selection	5688879
127286765	127286788	6	-	27260156	A673	viability	ATAGCAGAAAACGTGCTTACAGG	RNF146	ENSG00000118518	-0.47827070013061546	[139]	[99,181,73,122]	-8	hSpCas9	negative selection	5753131
127286832	127286855	6	+	27260156	A673	viability	TTGTCGACAAGAAATTCCCGAGG	RNF146	ENSG00000118518	-0.1102279048997622	[443]	[582,454,487,457]	-3	hSpCas9	negative selection	5753132
127286701	127286724	6	-	27260156	A673	viability	CATTCAGGGACGGTTAAAGAAGG	RNF146	ENSG00000118518	-0.5643894948758761	[212]	[217,113,207,156]	-8	hSpCas9	negative selection	5753133
127287661	127287684	6	-	27260156	A375	viability	GTTACTGTGCACTGTCCATCAGG	RNF146	ENSG00000118518	0.36158802325771466	[59]	[114,96,86,64]	5	hSpCas9	negative selection	5810128
127287276	127287299	6	-	27260156	A375	viability	ACTGACCATCTACTGATGTTAGG	RNF146	ENSG00000118518	-0.13115198633966907	[442]	[452,638,438,389]	-2	hSpCas9	negative selection	5810129
127286967	127286990	6	+	27260156	A375	viability	TGAGCGCACTAGTAGAGAGCTGG	RNF146	ENSG00000118518	-0.5815302884360896	[139]	[99,55,115,151]	-7	hSpCas9	negative selection	5810130
127286765	127286788	6	-	27260156	A375	viability	ATAGCAGAAAACGTGCTTACAGG	RNF146	ENSG00000118518	0.37515895031594115	[139]	[323,207,142,176]	5	hSpCas9	negative selection	5874382
127286832	127286855	6	+	27260156	A375	viability	TTGTCGACAAGAAATTCCCGAGG	RNF146	ENSG00000118518	0.09297659826469082	[443]	[693,658,485,404]	1	hSpCas9	negative selection	5874383
127286701	127286724	6	-	27260156	A375	viability	CATTCAGGGACGGTTAAAGAAGG	RNF146	ENSG00000118518	-0.05956897759862989	[212]	[200,195,332,219]	-1	hSpCas9	negative selection	5874384
127287661	127287684	6	-	27260156	COLO741	viability	GTTACTGTGCACTGTCCATCAGG	RNF146	ENSG00000118518	0.43648556415782647	[59]	[102,90,115]	8	hSpCas9	negative selection	5931379
127287276	127287299	6	-	27260156	COLO741	viability	ACTGACCATCTACTGATGTTAGG	RNF146	ENSG00000118518	-0.042524343584086396	[442]	[602,555,496]	-1	hSpCas9	negative selection	5931380
127286967	127286990	6	+	27260156	COLO741	viability	TGAGCGCACTAGTAGAGAGCTGG	RNF146	ENSG00000118518	0.0780554334207606	[139]	[298,112,164]	1	hSpCas9	negative selection	5931381
127286765	127286788	6	-	27260156	COLO741	viability	ATAGCAGAAAACGTGCTTACAGG	RNF146	ENSG00000118518	-0.586353428435864	[139]	[92,156,105]	-8	hSpCas9	negative selection	5995633
127286832	127286855	6	+	27260156	COLO741	viability	TTGTCGACAAGAAATTCCCGAGG	RNF146	ENSG00000118518	-0.21236495691112917	[443]	[620,385,472]	-4	hSpCas9	negative selection	5995634
127286701	127286724	6	-	27260156	COLO741	viability	CATTCAGGGACGGTTAAAGAAGG	RNF146	ENSG00000118518	-0.08396383287612497	[212]	[315,248,212]	-2	hSpCas9	negative selection	5995635
127287661	127287684	6	-	27260156	CAL120	viability	GTTACTGTGCACTGTCCATCAGG	RNF146	ENSG00000118518	1.0451731197836425	[59]	[97,160,193]	9	hSpCas9	negative selection	6052630
127287276	127287299	6	-	27260156	CAL120	viability	ACTGACCATCTACTGATGTTAGG	RNF146	ENSG00000118518	0.47654494970831546	[442]	[945,742,640]	7	hSpCas9	negative selection	6052631
127286967	127286990	6	+	27260156	CAL120	viability	TGAGCGCACTAGTAGAGAGCTGG	RNF146	ENSG00000118518	0.9785555794767392	[139]	[123,376,492]	9	hSpCas9	negative selection	6052632
127286765	127286788	6	-	27260156	CAL120	viability	ATAGCAGAAAACGTGCTTACAGG	RNF146	ENSG00000118518	-0.481783733498665	[139]	[152,130,94]	-6	hSpCas9	negative selection	6116884
127286832	127286855	6	+	27260156	CAL120	viability	TTGTCGACAAGAAATTCCCGAGG	RNF146	ENSG00000118518	0.30709664953682975	[443]	[818,634,617]	4	hSpCas9	negative selection	6116885
127286701	127286724	6	-	27260156	CAL120	viability	CATTCAGGGACGGTTAAAGAAGG	RNF146	ENSG00000118518	0.7325913323782445	[212]	[406,409,497]	9	hSpCas9	negative selection	6116886
127287661	127287684	6	-	27260156	CADOES1	viability	GTTACTGTGCACTGTCCATCAGG	RNF146	ENSG00000118518	0.6484641646068483	[59]	[36,74,47,193]	9	hSpCas9	negative selection	6173881
127287276	127287299	6	-	27260156	CADOES1	viability	ACTGACCATCTACTGATGTTAGG	RNF146	ENSG00000118518	0.16872887090251132	[442]	[436,404,609,397]	3	hSpCas9	negative selection	6173882
127286967	127286990	6	+	27260156	CADOES1	viability	TGAGCGCACTAGTAGAGAGCTGG	RNF146	ENSG00000118518	-0.25586080699070823	[139]	[162,89,99,81]	-4	hSpCas9	negative selection	6173883
127286765	127286788	6	-	27260156	CADOES1	viability	ATAGCAGAAAACGTGCTTACAGG	RNF146	ENSG00000118518	0.5043299645250494	[139]	[235,127,126,249]	8	hSpCas9	negative selection	6238135
127286832	127286855	6	+	27260156	CADOES1	viability	TTGTCGACAAGAAATTCCCGAGG	RNF146	ENSG00000118518	0.04621292555663518	[443]	[511,334,307,554]	0	hSpCas9	negative selection	6238136
127286701	127286724	6	-	27260156	CADOES1	viability	CATTCAGGGACGGTTAAAGAAGG	RNF146	ENSG00000118518	-0.1327910690666647	[212]	[124,212,227,155]	-2	hSpCas9	negative selection	6238137
127287661	127287684	6	-	27260156	EWS502	viability	GTTACTGTGCACTGTCCATCAGG	RNF146	ENSG00000118518	0.7090797901806227	[59]	[99,59,123,135]	9	hSpCas9	negative selection	6295132
127287276	127287299	6	-	27260156	EWS502	viability	ACTGACCATCTACTGATGTTAGG	RNF146	ENSG00000118518	0.4774978208357115	[442]	[751,558,851,425]	8	hSpCas9	negative selection	6295133
127286967	127286990	6	+	27260156	EWS502	viability	TGAGCGCACTAGTAGAGAGCTGG	RNF146	ENSG00000118518	-0.5630695945169428	[139]	[111,115,47,123]	-7	hSpCas9	negative selection	6295134
127286765	127286788	6	-	27260156	EWS502	viability	ATAGCAGAAAACGTGCTTACAGG	RNF146	ENSG00000118518	0.34866944473475536	[139]	[180,163,174,239]	6	hSpCas9	negative selection	6359386
127286832	127286855	6	+	27260156	EWS502	viability	TTGTCGACAAGAAATTCCCGAGG	RNF146	ENSG00000118518	-0.32879410213465826	[443]	[275,494,390,338]	-5	hSpCas9	negative selection	6359387
127286701	127286724	6	-	27260156	EWS502	viability	CATTCAGGGACGGTTAAAGAAGG	RNF146	ENSG00000118518	0.08040668156783592	[212]	[182,196,201,389]	1	hSpCas9	negative selection	6359388
127287661	127287684	6	-	27260156	EW8	viability	GTTACTGTGCACTGTCCATCAGG	RNF146	ENSG00000118518	0.6513046777495735	[59]	[158,78,31,51]	9	hSpCas9	negative selection	6416383
127287276	127287299	6	-	27260156	EW8	viability	ACTGACCATCTACTGATGTTAGG	RNF146	ENSG00000118518	0.32226460363539716	[442]	[577,353,460,412]	6	hSpCas9	negative selection	6416384
127286967	127286990	6	+	27260156	EW8	viability	TGAGCGCACTAGTAGAGAGCTGG	RNF146	ENSG00000118518	-0.24837230258015786	[139]	[66,119,99,90]	-5	hSpCas9	negative selection	6416385
127286765	127286788	6	-	27260156	EW8	viability	ATAGCAGAAAACGTGCTTACAGG	RNF146	ENSG00000118518	-0.31436336217473704	[139]	[147,70,78,74]	-5	hSpCas9	negative selection	6480637
127286832	127286855	6	+	27260156	EW8	viability	TTGTCGACAAGAAATTCCCGAGG	RNF146	ENSG00000118518	-0.12281715260152123	[443]	[356,401,266,308]	-2	hSpCas9	negative selection	6480638
127286701	127286724	6	-	27260156	EW8	viability	CATTCAGGGACGGTTAAAGAAGG	RNF146	ENSG00000118518	0.16969170162330338	[212]	[269,170,160,187]	3	hSpCas9	negative selection	6480639
127287661	127287684	6	-	27260156	CORL105	viability	GTTACTGTGCACTGTCCATCAGG	RNF146	ENSG00000118518	0.7106237890269069	[59]	[81,48,192,147]	9	hSpCas9	negative selection	6537634
127287276	127287299	6	-	27260156	CORL105	viability	ACTGACCATCTACTGATGTTAGG	RNF146	ENSG00000118518	0.16332981312059786	[442]	[551,561,748,485]	3	hSpCas9	negative selection	6537635
127286967	127286990	6	+	27260156	CORL105	viability	TGAGCGCACTAGTAGAGAGCTGG	RNF146	ENSG00000118518	-0.07673314794785258	[139]	[182,103,133,198]	-1	hSpCas9	negative selection	6537636
127286765	127286788	6	-	27260156	CORL105	viability	ATAGCAGAAAACGTGCTTACAGG	RNF146	ENSG00000118518	-0.07740956975290114	[139]	[152,194,157,114]	-1	hSpCas9	negative selection	6601888
127286832	127286855	6	+	27260156	CORL105	viability	TTGTCGACAAGAAATTCCCGAGG	RNF146	ENSG00000118518	-0.3604141119512647	[443]	[509,414,471,236]	-6	hSpCas9	negative selection	6601889
127286701	127286724	6	-	27260156	CORL105	viability	CATTCAGGGACGGTTAAAGAAGG	RNF146	ENSG00000118518	-0.07948401169405428	[212]	[255,217,223,244]	-1	hSpCas9	negative selection	6601890
127287661	127287684	6	-	27260156	HS294T	viability	GTTACTGTGCACTGTCCATCAGG	RNF146	ENSG00000118518	-0.22165705879554487	[59]	[22,11,16,28]	-3	hSpCas9	negative selection	6658885
127287276	127287299	6	-	27260156	HS294T	viability	ACTGACCATCTACTGATGTTAGG	RNF146	ENSG00000118518	0.31369774893486974	[442]	[156,366,113,212]	4	hSpCas9	negative selection	6658886
127286967	127286990	6	+	27260156	HS294T	viability	TGAGCGCACTAGTAGAGAGCTGG	RNF146	ENSG00000118518	-0.6111027998685374	[139]	[16,45,24,58]	-7	hSpCas9	negative selection	6658887
127286765	127286788	6	-	27260156	HS294T	viability	ATAGCAGAAAACGTGCTTACAGG	RNF146	ENSG00000118518	0.2710377575251508	[139]	[38,47,42,147]	3	hSpCas9	negative selection	6723139
127286832	127286855	6	+	27260156	HS294T	viability	TTGTCGACAAGAAATTCCCGAGG	RNF146	ENSG00000118518	-0.3466582294081367	[443]	[99,114,171,160]	-5	hSpCas9	negative selection	6723140
127286701	127286724	6	-	27260156	HS294T	viability	CATTCAGGGACGGTTAAAGAAGG	RNF146	ENSG00000118518	0.525372703104807	[212]	[91,202,101,67]	7	hSpCas9	negative selection	6723141
127287661	127287684	6	-	27260156	HCC44	viability	GTTACTGTGCACTGTCCATCAGG	RNF146	ENSG00000118518	0.9839407166598488	[59]	[67,163,130,160]	9	hSpCas9	negative selection	6780136
127287276	127287299	6	-	27260156	HCC44	viability	ACTGACCATCTACTGATGTTAGG	RNF146	ENSG00000118518	0.17536489630492785	[442]	[462,430,708,685]	3	hSpCas9	negative selection	6780137
127286967	127286990	6	+	27260156	HCC44	viability	TGAGCGCACTAGTAGAGAGCTGG	RNF146	ENSG00000118518	0.17729588113775896	[139]	[314,140,152,120]	3	hSpCas9	negative selection	6780138
127286765	127286788	6	-	27260156	HCC44	viability	ATAGCAGAAAACGTGCTTACAGG	RNF146	ENSG00000118518	0.046024449780896814	[139]	[213,123,103,208]	0	hSpCas9	negative selection	6844390
127286832	127286855	6	+	27260156	HCC44	viability	TTGTCGACAAGAAATTCCCGAGG	RNF146	ENSG00000118518	0.07446294384881104	[443]	[695,418,630,416]	1	hSpCas9	negative selection	6844391
127286701	127286724	6	-	27260156	HCC44	viability	CATTCAGGGACGGTTAAAGAAGG	RNF146	ENSG00000118518	0.23076545640644486	[212]	[326,304,194,286]	3	hSpCas9	negative selection	6844392
127287661	127287684	6	-	27260156	G402	viability	GTTACTGTGCACTGTCCATCAGG	RNF146	ENSG00000118518	-1.107246030413298	[59]	[93,13,15,19]	-8	hSpCas9	negative selection	6901387
127287276	127287299	6	-	27260156	G402	viability	ACTGACCATCTACTGATGTTAGG	RNF146	ENSG00000118518	0.4532139970143823	[442]	[1334,568,572,564]	5	hSpCas9	negative selection	6901388
127286967	127286990	6	+	27260156	G402	viability	TGAGCGCACTAGTAGAGAGCTGG	RNF146	ENSG00000118518	-0.6071411942938951	[139]	[46,66,58,255]	-6	hSpCas9	negative selection	6901389
127286765	127286788	6	-	27260156	G402	viability	ATAGCAGAAAACGTGCTTACAGG	RNF146	ENSG00000118518	0.01665315571441539	[139]	[203,79,175,226]	0	hSpCas9	negative selection	6965641
127286832	127286855	6	+	27260156	G402	viability	TTGTCGACAAGAAATTCCCGAGG	RNF146	ENSG00000118518	-0.11970226287501115	[443]	[556,600,350,497]	-1	hSpCas9	negative selection	6965642
127286701	127286724	6	-	27260156	G402	viability	CATTCAGGGACGGTTAAAGAAGG	RNF146	ENSG00000118518	0.6734713600685519	[212]	[635,247,384,409]	8	hSpCas9	negative selection	6965643
127287661	127287684	6	-	27260156	L33	viability	GTTACTGTGCACTGTCCATCAGG	RNF146	ENSG00000118518	0.08549013241544623	[59]	[66,16,50,64]	2	hSpCas9	negative selection	7022638
127287276	127287299	6	-	27260156	L33	viability	ACTGACCATCTACTGATGTTAGG	RNF146	ENSG00000118518	0.3663809310286491	[442]	[448,225,397,652]	7	hSpCas9	negative selection	7022639
127286967	127286990	6	+	27260156	L33	viability	TGAGCGCACTAGTAGAGAGCTGG	RNF146	ENSG00000118518	-0.5139292819354981	[139]	[118,32,83,58]	-8	hSpCas9	negative selection	7022640
127286765	127286788	6	-	27260156	L33	viability	ATAGCAGAAAACGTGCTTACAGG	RNF146	ENSG00000118518	-0.3559124598421688	[139]	[71,37,60,175]	-7	hSpCas9	negative selection	7086892
127286832	127286855	6	+	27260156	L33	viability	TTGTCGACAAGAAATTCCCGAGG	RNF146	ENSG00000118518	-0.3571259386090137	[443]	[467,131,158,339]	-7	hSpCas9	negative selection	7086893
127286701	127286724	6	-	27260156	L33	viability	CATTCAGGGACGGTTAAAGAAGG	RNF146	ENSG00000118518	0.08989262675329868	[212]	[192,113,135,219]	2	hSpCas9	negative selection	7086894
127287661	127287684	6	-	27260156	K562	viability	GTTACTGTGCACTGTCCATCAGG	RNF146	ENSG00000118518	0.4583320140386822	[59]	[69,31,77,105]	6	hSpCas9	negative selection	7143889
127287276	127287299	6	-	27260156	K562	viability	ACTGACCATCTACTGATGTTAGG	RNF146	ENSG00000118518	0.17893410643920543	[442]	[417,443,468,444]	2	hSpCas9	negative selection	7143890
127286967	127286990	6	+	27260156	K562	viability	TGAGCGCACTAGTAGAGAGCTGG	RNF146	ENSG00000118518	-0.27816165953552696	[139]	[134,19,152,99]	-3	hSpCas9	negative selection	7143891
127286765	127286788	6	-	27260156	K562	viability	ATAGCAGAAAACGTGCTTACAGG	RNF146	ENSG00000118518	-0.1600939056501054	[139]	[78,232,80,60]	-2	hSpCas9	negative selection	7208143
127286832	127286855	6	+	27260156	K562	viability	TTGTCGACAAGAAATTCCCGAGG	RNF146	ENSG00000118518	-0.9590927511416182	[443]	[216,304,106,188]	-8	hSpCas9	negative selection	7208144
127286701	127286724	6	-	27260156	K562	viability	CATTCAGGGACGGTTAAAGAAGG	RNF146	ENSG00000118518	-1.2723166799366021	[212]	[66,89,82,72]	-8	hSpCas9	negative selection	7208145
127287661	127287684	6	-	27260156	HT29	viability	GTTACTGTGCACTGTCCATCAGG	RNF146	ENSG00000118518	0.7398829804668838	[59]	[149,140,75,122]	9	hSpCas9	negative selection	7265140
127287276	127287299	6	-	27260156	HT29	viability	ACTGACCATCTACTGATGTTAGG	RNF146	ENSG00000118518	0.04623134375463893	[442]	[567,551,609,497]	0	hSpCas9	negative selection	7265141
127286967	127286990	6	+	27260156	HT29	viability	TGAGCGCACTAGTAGAGAGCTGG	RNF146	ENSG00000118518	-0.29786129854800203	[139]	[183,170,145,66]	-5	hSpCas9	negative selection	7265142
127286765	127286788	6	-	27260156	HT29	viability	ATAGCAGAAAACGTGCTTACAGG	RNF146	ENSG00000118518	0.15103645299786472	[139]	[181,187,204,179]	3	hSpCas9	negative selection	7329394
127286832	127286855	6	+	27260156	HT29	viability	TTGTCGACAAGAAATTCCCGAGG	RNF146	ENSG00000118518	-0.1985945623908888	[443]	[575,440,418,449]	-4	hSpCas9	negative selection	7329395
127286701	127286724	6	-	27260156	HT29	viability	CATTCAGGGACGGTTAAAGAAGG	RNF146	ENSG00000118518	-0.39460647309604213	[212]	[240,172,205,170]	-6	hSpCas9	negative selection	7329396
127287661	127287684	6	-	27260156	MHHES1	viability	GTTACTGTGCACTGTCCATCAGG	RNF146	ENSG00000118518	0.7379023505780635	[59]	[50,150,85,147]	9	hSpCas9	negative selection	7386391
127287276	127287299	6	-	27260156	MHHES1	viability	ACTGACCATCTACTGATGTTAGG	RNF146	ENSG00000118518	0.15218444839479833	[442]	[585,543,591,498]	3	hSpCas9	negative selection	7386392
127286967	127286990	6	+	27260156	MHHES1	viability	TGAGCGCACTAGTAGAGAGCTGG	RNF146	ENSG00000118518	-0.5858426862605017	[139]	[106,179,77,68]	-8	hSpCas9	negative selection	7386393
127286765	127286788	6	-	27260156	MHHES1	viability	ATAGCAGAAAACGTGCTTACAGG	RNF146	ENSG00000118518	-1.0482679572752431	[139]	[42,95,104,60]	-9	hSpCas9	negative selection	7450645
127286832	127286855	6	+	27260156	MHHES1	viability	TTGTCGACAAGAAATTCCCGAGG	RNF146	ENSG00000118518	-0.24681976326681138	[443]	[440,346,562,339]	-5	hSpCas9	negative selection	7450646
127286701	127286724	6	-	27260156	MHHES1	viability	CATTCAGGGACGGTTAAAGAAGG	RNF146	ENSG00000118518	-0.9457851478496715	[212]	[114,209,111,76]	-9	hSpCas9	negative selection	7450647
127287661	127287684	6	-	27260156	MEWO	viability	GTTACTGTGCACTGTCCATCAGG	RNF146	ENSG00000118518	1.1131442803475358	[59]	[135,136,93]	9	hSpCas9	negative selection	7507642
127287276	127287299	6	-	27260156	MEWO	viability	ACTGACCATCTACTGATGTTAGG	RNF146	ENSG00000118518	0.0031290004911269237	[442]	[389,426,423]	0	hSpCas9	negative selection	7507643
127286967	127286990	6	+	27260156	MEWO	viability	TGAGCGCACTAGTAGAGAGCTGG	RNF146	ENSG00000118518	-0.8280368999907721	[139]	[107,63,55]	-9	hSpCas9	negative selection	7507644
127286765	127286788	6	-	27260156	MEWO	viability	ATAGCAGAAAACGTGCTTACAGG	RNF146	ENSG00000118518	-0.5577306597676142	[139]	[99,101,66]	-8	hSpCas9	negative selection	7571896
127286832	127286855	6	+	27260156	MEWO	viability	TTGTCGACAAGAAATTCCCGAGG	RNF146	ENSG00000118518	-0.19619319411117003	[443]	[469,249,388]	-4	hSpCas9	negative selection	7571897
127286701	127286724	6	-	27260156	MEWO	viability	CATTCAGGGACGGTTAAAGAAGG	RNF146	ENSG00000118518	-0.8804812206692869	[212]	[129,91,106]	-9	hSpCas9	negative selection	7571898
127287661	127287684	6	-	27260156	LNCAPCLONEFGC	viability	GTTACTGTGCACTGTCCATCAGG	RNF146	ENSG00000118518	0.8095484175554071	[59]	[78,112,80,104]	9	hSpCas9	negative selection	7628893
127287276	127287299	6	-	27260156	LNCAPCLONEFGC	viability	ACTGACCATCTACTGATGTTAGG	RNF146	ENSG00000118518	0.22553364213337584	[442]	[392,435,447,599]	3	hSpCas9	negative selection	7628894
127286967	127286990	6	+	27260156	LNCAPCLONEFGC	viability	TGAGCGCACTAGTAGAGAGCTGG	RNF146	ENSG00000118518	-0.9106792180575503	[139]	[101,42,48,73]	-8	hSpCas9	negative selection	7628895
127286765	127286788	6	-	27260156	LNCAPCLONEFGC	viability	ATAGCAGAAAACGTGCTTACAGG	RNF146	ENSG00000118518	0.4226616388995146	[139]	[132,183,313,69]	6	hSpCas9	negative selection	7693147
127286832	127286855	6	+	27260156	LNCAPCLONEFGC	viability	TTGTCGACAAGAAATTCCCGAGG	RNF146	ENSG00000118518	-0.752104696092287	[443]	[235,266,243,206]	-8	hSpCas9	negative selection	7693148
127286701	127286724	6	-	27260156	LNCAPCLONEFGC	viability	CATTCAGGGACGGTTAAAGAAGG	RNF146	ENSG00000118518	-0.1972496052540078	[212]	[128,180,154,205]	-3	hSpCas9	negative selection	7693149
127287661	127287684	6	-	27260156	PANC0327	viability	GTTACTGTGCACTGTCCATCAGG	RNF146	ENSG00000118518	1.1163385096028637	[59]	[41,91,69,254]	9	hSpCas9	negative selection	7750144
127287276	127287299	6	-	27260156	PANC0327	viability	ACTGACCATCTACTGATGTTAGG	RNF146	ENSG00000118518	0.07733266291519772	[442]	[768,233,365,343]	1	hSpCas9	negative selection	7750145
127286967	127286990	6	+	27260156	PANC0327	viability	TGAGCGCACTAGTAGAGAGCTGG	RNF146	ENSG00000118518	-0.2088732746207147	[139]	[79,85,165,98]	-3	hSpCas9	negative selection	7750146
127286765	127286788	6	-	27260156	PANC0327	viability	ATAGCAGAAAACGTGCTTACAGG	RNF146	ENSG00000118518	-0.24593025613607922	[139]	[38,150,64,152]	-4	hSpCas9	negative selection	7814398
127286832	127286855	6	+	27260156	PANC0327	viability	TTGTCGACAAGAAATTCCCGAGG	RNF146	ENSG00000118518	-0.24634689665367243	[443]	[260,587,250,190]	-4	hSpCas9	negative selection	7814399
127286701	127286724	6	-	27260156	PANC0327	viability	CATTCAGGGACGGTTAAAGAAGG	RNF146	ENSG00000118518	0.004554447151290386	[212]	[296,82,300,100]	0	hSpCas9	negative selection	7814400
127287661	127287684	6	-	27260156	NCIH2009	viability	GTTACTGTGCACTGTCCATCAGG	RNF146	ENSG00000118518	-0.5337221442725189	[59]	[58,48,65]	-6	hSpCas9	negative selection	7871395
127287276	127287299	6	-	27260156	NCIH2009	viability	ACTGACCATCTACTGATGTTAGG	RNF146	ENSG00000118518	0.08166856614285221	[442]	[755,644,582]	1	hSpCas9	negative selection	7871396
127286967	127286990	6	+	27260156	NCIH2009	viability	TGAGCGCACTAGTAGAGAGCTGG	RNF146	ENSG00000118518	0.023809763704573772	[139]	[261,127,219]	0	hSpCas9	negative selection	7871397
127286765	127286788	6	-	27260156	NCIH2009	viability	ATAGCAGAAAACGTGCTTACAGG	RNF146	ENSG00000118518	-0.014067236520020954	[139]	[155,266,148]	0	hSpCas9	negative selection	7935649
127286832	127286855	6	+	27260156	NCIH2009	viability	TTGTCGACAAGAAATTCCCGAGG	RNF146	ENSG00000118518	0.2489510730816374	[443]	[1278,536,504]	3	hSpCas9	negative selection	7935650
127286701	127286724	6	-	27260156	NCIH2009	viability	CATTCAGGGACGGTTAAAGAAGG	RNF146	ENSG00000118518	0.5678443420465137	[212]	[403,346,565]	7	hSpCas9	negative selection	7935651
127287661	127287684	6	-	27260156	NCIH1373	viability	GTTACTGTGCACTGTCCATCAGG	RNF146	ENSG00000118518	-0.8920748079474041	[59]	[85,41,7,3]	-7	hSpCas9	negative selection	7992646
127287276	127287299	6	-	27260156	NCIH1373	viability	ACTGACCATCTACTGATGTTAGG	RNF146	ENSG00000118518	0.47772245901240507	[442]	[413,678,750,232]	5	hSpCas9	negative selection	7992647
127286967	127286990	6	+	27260156	NCIH1373	viability	TGAGCGCACTAGTAGAGAGCTGG	RNF146	ENSG00000118518	-1.3154970863826185	[139]	[36,42,107,15]	-8	hSpCas9	negative selection	7992648
127286765	127286788	6	-	27260156	NCIH1373	viability	ATAGCAGAAAACGTGCTTACAGG	RNF146	ENSG00000118518	0.43092932615352497	[139]	[293,105,132,90]	4	hSpCas9	negative selection	8056900
127286832	127286855	6	+	27260156	NCIH1373	viability	TTGTCGACAAGAAATTCCCGAGG	RNF146	ENSG00000118518	0.2117166375157159	[443]	[946,255,577,161]	2	hSpCas9	negative selection	8056901
127286701	127286724	6	-	27260156	NCIH1373	viability	CATTCAGGGACGGTTAAAGAAGG	RNF146	ENSG00000118518	0.2621298481079647	[212]	[176,381,138,112]	2	hSpCas9	negative selection	8056902
127287661	127287684	6	-	27260156	PATU8902	viability	GTTACTGTGCACTGTCCATCAGG	RNF146	ENSG00000118518	1.56308069221736	[59]	[189,616,123,66]	9	hSpCas9	negative selection	8113897
127287276	127287299	6	-	27260156	PATU8902	viability	ACTGACCATCTACTGATGTTAGG	RNF146	ENSG00000118518	0.1739203854063847	[442]	[931,711,507,668]	1	hSpCas9	negative selection	8113898
127286967	127286990	6	+	27260156	PATU8902	viability	TGAGCGCACTAGTAGAGAGCTGG	RNF146	ENSG00000118518	-0.7379591102357455	[139]	[12,145,140,167]	-6	hSpCas9	negative selection	8113899
127286765	127286788	6	-	27260156	PATU8902	viability	ATAGCAGAAAACGTGCTTACAGG	RNF146	ENSG00000118518	0.4153421940923949	[139]	[265,635,69,96]	4	hSpCas9	negative selection	8178151
127286832	127286855	6	+	27260156	PATU8902	viability	TTGTCGACAAGAAATTCCCGAGG	RNF146	ENSG00000118518	-0.34390096755907545	[443]	[888,274,553,164]	-3	hSpCas9	negative selection	8178152
127286701	127286724	6	-	27260156	PATU8902	viability	CATTCAGGGACGGTTAAAGAAGG	RNF146	ENSG00000118518	-0.15394717317031703	[212]	[270,491,35,333]	-1	hSpCas9	negative selection	8178153
127287661	127287684	6	-	27260156	PANC1	viability	GTTACTGTGCACTGTCCATCAGG	RNF146	ENSG00000118518	0.708493039212887	[59]	[79,94,139,31]	9	hSpCas9	negative selection	8235148
127287276	127287299	6	-	27260156	PANC1	viability	ACTGACCATCTACTGATGTTAGG	RNF146	ENSG00000118518	0.31127540901332973	[442]	[492,703,382,364]	5	hSpCas9	negative selection	8235149
127286967	127286990	6	+	27260156	PANC1	viability	TGAGCGCACTAGTAGAGAGCTGG	RNF146	ENSG00000118518	-0.5303005611616052	[139]	[69,210,29,51]	-7	hSpCas9	negative selection	8235150
127286765	127286788	6	-	27260156	PANC1	viability	ATAGCAGAAAACGTGCTTACAGG	RNF146	ENSG00000118518	-0.1142096702558284	[139]	[97,82,129,123]	-2	hSpCas9	negative selection	8299402
127286832	127286855	6	+	27260156	PANC1	viability	TTGTCGACAAGAAATTCCCGAGG	RNF146	ENSG00000118518	-0.42255913758258246	[443]	[234,501,195,250]	-6	hSpCas9	negative selection	8299403
127286701	127286724	6	-	27260156	PANC1	viability	CATTCAGGGACGGTTAAAGAAGG	RNF146	ENSG00000118518	-0.2402939116948677	[212]	[126,258,173,89]	-4	hSpCas9	negative selection	8299404
127287661	127287684	6	-	27260156	PANC0813	viability	GTTACTGTGCACTGTCCATCAGG	RNF146	ENSG00000118518	0.7591724624145884	[59]	[156,174,97,53]	9	hSpCas9	negative selection	8356399
127287276	127287299	6	-	27260156	PANC0813	viability	ACTGACCATCTACTGATGTTAGG	RNF146	ENSG00000118518	0.1322177582840181	[442]	[605,488,534,648]	2	hSpCas9	negative selection	8356400
127286967	127286990	6	+	27260156	PANC0813	viability	TGAGCGCACTAGTAGAGAGCTGG	RNF146	ENSG00000118518	-0.13134752749579515	[139]	[93,142,269,91]	-2	hSpCas9	negative selection	8356401
127286765	127286788	6	-	27260156	PANC0813	viability	ATAGCAGAAAACGTGCTTACAGG	RNF146	ENSG00000118518	-0.04102339913875985	[139]	[134,226,156,119]	0	hSpCas9	negative selection	8420653
127286832	127286855	6	+	27260156	PANC0813	viability	TTGTCGACAAGAAATTCCCGAGG	RNF146	ENSG00000118518	0.22061852281629965	[443]	[719,613,485,618]	3	hSpCas9	negative selection	8420654
127286701	127286724	6	-	27260156	PANC0813	viability	CATTCAGGGACGGTTAAAGAAGG	RNF146	ENSG00000118518	0.3476307878790592	[212]	[304,250,463,255]	5	hSpCas9	negative selection	8420655
127287661	127287684	6	-	27260156	RDES	viability	GTTACTGTGCACTGTCCATCAGG	RNF146	ENSG00000118518	0.4764830256610284	[59]	[81,85,165,45]	7	hSpCas9	negative selection	8477650
127287276	127287299	6	-	27260156	RDES	viability	ACTGACCATCTACTGATGTTAGG	RNF146	ENSG00000118518	0.22274886210564732	[442]	[511,541,715,620]	3	hSpCas9	negative selection	8477651
127286967	127286990	6	+	27260156	RDES	viability	TGAGCGCACTAGTAGAGAGCTGG	RNF146	ENSG00000118518	-0.4501422944660698	[139]	[72,99,144,170]	-6	hSpCas9	negative selection	8477652
127286765	127286788	6	-	27260156	RDES	viability	ATAGCAGAAAACGTGCTTACAGG	RNF146	ENSG00000118518	0.1127057739306887	[139]	[152,162,175,209]	1	hSpCas9	negative selection	8541904
127286832	127286855	6	+	27260156	RDES	viability	TTGTCGACAAGAAATTCCCGAGG	RNF146	ENSG00000118518	-0.26829877225296217	[443]	[301,473,354,597]	-4	hSpCas9	negative selection	8541905
127286701	127286724	6	-	27260156	RDES	viability	CATTCAGGGACGGTTAAAGAAGG	RNF146	ENSG00000118518	-0.4905617319676514	[212]	[133,130,210,240]	-7	hSpCas9	negative selection	8541906
127287661	127287684	6	-	27260156	PC3	viability	GTTACTGTGCACTGTCCATCAGG	RNF146	ENSG00000118518	0.5899715590482115	[59]	[70,94,90,100]	9	hSpCas9	negative selection	8598901
127287276	127287299	6	-	27260156	PC3	viability	ACTGACCATCTACTGATGTTAGG	RNF146	ENSG00000118518	0.28527891597557303	[442]	[339,678,886,400]	6	hSpCas9	negative selection	8598902
127286967	127286990	6	+	27260156	PC3	viability	TGAGCGCACTAGTAGAGAGCTGG	RNF146	ENSG00000118518	-0.002568581564757144	[139]	[97,105,290,125]	0	hSpCas9	negative selection	8598903
127286765	127286788	6	-	27260156	PC3	viability	ATAGCAGAAAACGTGCTTACAGG	RNF146	ENSG00000118518	0.3499465487260067	[139]	[98,305,188,129]	7	hSpCas9	negative selection	8663155
127286832	127286855	6	+	27260156	PC3	viability	TTGTCGACAAGAAATTCCCGAGG	RNF146	ENSG00000118518	-0.44571834478787264	[443]	[290,295,575,201]	-7	hSpCas9	negative selection	8663156
127286701	127286724	6	-	27260156	PC3	viability	CATTCAGGGACGGTTAAAGAAGG	RNF146	ENSG00000118518	-0.13158916530331255	[212]	[136,178,360,166]	-3	hSpCas9	negative selection	8663157
127287661	127287684	6	-	27260156	PATU8988T	viability	GTTACTGTGCACTGTCCATCAGG	RNF146	ENSG00000118518	0.8045743150952918	[59]	[61,97,163,77]	9	hSpCas9	negative selection	8720152
127287276	127287299	6	-	27260156	PATU8988T	viability	ACTGACCATCTACTGATGTTAGG	RNF146	ENSG00000118518	0.1465488851383801	[442]	[515,513,455,407]	2	hSpCas9	negative selection	8720153
127286967	127286990	6	+	27260156	PATU8988T	viability	TGAGCGCACTAGTAGAGAGCTGG	RNF146	ENSG00000118518	-0.1183753846405422	[139]	[82,169,92,159]	-2	hSpCas9	negative selection	8720154
127286765	127286788	6	-	27260156	PATU8988T	viability	ATAGCAGAAAACGTGCTTACAGG	RNF146	ENSG00000118518	-1.1231116331404483	[139]	[22,58,59,109]	-9	hSpCas9	negative selection	8784406
127286832	127286855	6	+	27260156	PATU8988T	viability	TTGTCGACAAGAAATTCCCGAGG	RNF146	ENSG00000118518	0.3168099097523812	[443]	[754,357,374,643]	5	hSpCas9	negative selection	8784407
127286701	127286724	6	-	27260156	PATU8988T	viability	CATTCAGGGACGGTTAAAGAAGG	RNF146	ENSG00000118518	-0.48880057572585645	[212]	[204,148,93,138]	-7	hSpCas9	negative selection	8784408
127287661	127287684	6	-	27260156	T47D	viability	GTTACTGTGCACTGTCCATCAGG	RNF146	ENSG00000118518	0.8235314154588331	[59]	[124,90,138,142]	9	hSpCas9	negative selection	8841403
127287276	127287299	6	-	27260156	T47D	viability	ACTGACCATCTACTGATGTTAGG	RNF146	ENSG00000118518	0.04370424571658313	[442]	[518,510,523,576]	0	hSpCas9	negative selection	8841404
127286967	127286990	6	+	27260156	T47D	viability	TGAGCGCACTAGTAGAGAGCTGG	RNF146	ENSG00000118518	-0.27764851478066355	[139]	[73,144,125,193]	-6	hSpCas9	negative selection	8841405
127286765	127286788	6	-	27260156	T47D	viability	ATAGCAGAAAACGTGCTTACAGG	RNF146	ENSG00000118518	-0.3035005085345124	[139]	[86,148,127,163]	-6	hSpCas9	negative selection	8905657
127286832	127286855	6	+	27260156	T47D	viability	TTGTCGACAAGAAATTCCCGAGG	RNF146	ENSG00000118518	-0.40395282133891697	[443]	[411,437,333,375]	-7	hSpCas9	negative selection	8905658
127286701	127286724	6	-	27260156	T47D	viability	CATTCAGGGACGGTTAAAGAAGG	RNF146	ENSG00000118518	0.25259445800192826	[212]	[175,202,583,219]	5	hSpCas9	negative selection	8905659
127287661	127287684	6	-	27260156	SU8686	viability	GTTACTGTGCACTGTCCATCAGG	RNF146	ENSG00000118518	0.15948866184324606	[59]	[51,37,71,116]	2	hSpCas9	negative selection	8962654
127287276	127287299	6	-	27260156	SU8686	viability	ACTGACCATCTACTGATGTTAGG	RNF146	ENSG00000118518	0.0021489521964981606	[442]	[336,485,410,543]	0	hSpCas9	negative selection	8962655
127286967	127286990	6	+	27260156	SU8686	viability	TGAGCGCACTAGTAGAGAGCTGG	RNF146	ENSG00000118518	-0.007099622744924927	[139]	[137,128,140,145]	0	hSpCas9	negative selection	8962656
127286765	127286788	6	-	27260156	SU8686	viability	ATAGCAGAAAACGTGCTTACAGG	RNF146	ENSG00000118518	0.038456587804055475	[139]	[173,121,177,85]	0	hSpCas9	negative selection	9026908
127286832	127286855	6	+	27260156	SU8686	viability	TTGTCGACAAGAAATTCCCGAGG	RNF146	ENSG00000118518	-0.25084898530825706	[443]	[344,304,384,469]	-4	hSpCas9	negative selection	9026909
127286701	127286724	6	-	27260156	SU8686	viability	CATTCAGGGACGGTTAAAGAAGG	RNF146	ENSG00000118518	-0.17350070090412895	[212]	[153,128,203,288]	-3	hSpCas9	negative selection	9026910
127287661	127287684	6	-	27260156	SKES1	viability	GTTACTGTGCACTGTCCATCAGG	RNF146	ENSG00000118518	0.31963333815165607	[59]	[38,83,55,110]	6	hSpCas9	negative selection	9083905
127287276	127287299	6	-	27260156	SKES1	viability	ACTGACCATCTACTGATGTTAGG	RNF146	ENSG00000118518	0.3602469289012642	[442]	[750,511,563,466]	7	hSpCas9	negative selection	9083906
127286967	127286990	6	+	27260156	SKES1	viability	TGAGCGCACTAGTAGAGAGCTGG	RNF146	ENSG00000118518	-0.7295619251643535	[139]	[60,58,122,85]	-9	hSpCas9	negative selection	9083907
127286765	127286788	6	-	27260156	SKES1	viability	ATAGCAGAAAACGTGCTTACAGG	RNF146	ENSG00000118518	0.6207281757643042	[139]	[189,197,291,174]	9	hSpCas9	negative selection	9148159
127286832	127286855	6	+	27260156	SKES1	viability	TTGTCGACAAGAAATTCCCGAGG	RNF146	ENSG00000118518	-0.09151753065987558	[443]	[421,370,502,362]	-2	hSpCas9	negative selection	9148160
127286701	127286724	6	-	27260156	SKES1	viability	CATTCAGGGACGGTTAAAGAAGG	RNF146	ENSG00000118518	0.06013915232362432	[212]	[282,258,155,201]	1	hSpCas9	negative selection	9148161
127287661	127287684	6	-	27260156	TOV112D	viability	GTTACTGTGCACTGTCCATCAGG	RNF146	ENSG00000118518	0.7460971654870825	[59]	[180,81,72,69]	9	hSpCas9	negative selection	9205156
127287276	127287299	6	-	27260156	TOV112D	viability	ACTGACCATCTACTGATGTTAGG	RNF146	ENSG00000118518	0.31454140262984065	[442]	[596,699,597,356]	6	hSpCas9	negative selection	9205157
127286967	127286990	6	+	27260156	TOV112D	viability	TGAGCGCACTAGTAGAGAGCTGG	RNF146	ENSG00000118518	-0.14130705620739592	[139]	[142,127,79,157]	-3	hSpCas9	negative selection	9205158
127286765	127286788	6	-	27260156	TOV112D	viability	ATAGCAGAAAACGTGCTTACAGG	RNF146	ENSG00000118518	-0.39703440470312	[139]	[93,147,52,138]	-7	hSpCas9	negative selection	9269410
127286832	127286855	6	+	27260156	TOV112D	viability	TTGTCGACAAGAAATTCCCGAGG	RNF146	ENSG00000118518	0.28641116601773214	[443]	[625,642,450,481]	5	hSpCas9	negative selection	9269411
127286701	127286724	6	-	27260156	TOV112D	viability	CATTCAGGGACGGTTAAAGAAGG	RNF146	ENSG00000118518	0.021619337516667336	[212]	[202,176,186,285]	0	hSpCas9	negative selection	9269412
127287661	127287684	6	-	27260156	TC71	viability	GTTACTGTGCACTGTCCATCAGG	RNF146	ENSG00000118518	0.3731216608739305	[59]	[55,106,93,75]	8	hSpCas9	negative selection	9326407
127287276	127287299	6	-	27260156	TC71	viability	ACTGACCATCTACTGATGTTAGG	RNF146	ENSG00000118518	0.09476774413984397	[442]	[467,511,472,581]	2	hSpCas9	negative selection	9326408
127286967	127286990	6	+	27260156	TC71	viability	TGAGCGCACTAGTAGAGAGCTGG	RNF146	ENSG00000118518	-0.2795395994995875	[139]	[175,137,82,95]	-6	hSpCas9	negative selection	9326409
127286765	127286788	6	-	27260156	TC71	viability	ATAGCAGAAAACGTGCTTACAGG	RNF146	ENSG00000118518	-0.528380204421512	[139]	[103,66,149,92]	-9	hSpCas9	negative selection	9390661
127286832	127286855	6	+	27260156	TC71	viability	TTGTCGACAAGAAATTCCCGAGG	RNF146	ENSG00000118518	-0.11538001734150413	[443]	[457,433,469,390]	-3	hSpCas9	negative selection	9390662
127286701	127286724	6	-	27260156	TC71	viability	CATTCAGGGACGGTTAAAGAAGG	RNF146	ENSG00000118518	-0.24418547444308603	[212]	[160,228,207,171]	-6	hSpCas9	negative selection	9390663
127287661	127287684	6	-	27260156	TC32	viability	GTTACTGTGCACTGTCCATCAGG	RNF146	ENSG00000118518	0.5135727614494741	[59]	[43,85,78,111]	8	hSpCas9	negative selection	9447658
127287276	127287299	6	-	27260156	TC32	viability	ACTGACCATCTACTGATGTTAGG	RNF146	ENSG00000118518	0.19021209133516773	[442]	[393,485,533,470]	3	hSpCas9	negative selection	9447659
127286967	127286990	6	+	27260156	TC32	viability	TGAGCGCACTAGTAGAGAGCTGG	RNF146	ENSG00000118518	0.005416626827374538	[139]	[101,151,200,68]	0	hSpCas9	negative selection	9447660
127286765	127286788	6	-	27260156	TC32	viability	ATAGCAGAAAACGTGCTTACAGG	RNF146	ENSG00000118518	0.14963386763485342	[139]	[121,136,171,154]	2	hSpCas9	negative selection	9511912
127286832	127286855	6	+	27260156	TC32	viability	TTGTCGACAAGAAATTCCCGAGG	RNF146	ENSG00000118518	-0.2261491231312321	[443]	[319,221,477,469]	-4	hSpCas9	negative selection	9511913
127286701	127286724	6	-	27260156	TC32	viability	CATTCAGGGACGGTTAAAGAAGG	RNF146	ENSG00000118518	0.15502865430940183	[212]	[200,200,255,236]	3	hSpCas9	negative selection	9511914
127286801	127286824	6	+	27869803	HPAFII	viability after 27 days	GAGCTTCATGGCTTGGAAAGCGG	RNF146	ENSG00000118518	0.6538806399845405	[352]	[471,141,NaN]	5	hSpCas9	negative selection	9593521
127286832	127286855	6	+	27869803	HPAFII	viability after 27 days	TTGTCGACAAGAAATTCCCGAGG	RNF146	ENSG00000118518	-0.3674477580343145	[668]	[234,303,NaN]	-3	hSpCas9	negative selection	9593522
127286873	127286896	6	-	27869803	HPAFII	viability after 27 days	GAGTTCTTCTGGTGACAACAAGG	RNF146	ENSG00000118518	0.8315535666019277	[143]	[59,196,NaN]	6	hSpCas9	negative selection	9593523
127287217	127287240	6	+	27869803	HPAFII	viability after 27 days	GACAGTGTATCAGCACAGAGTGG	RNF146	ENSG00000118518	0.5469554807747609	[235]	[135,218,NaN]	4	hSpCas9	negative selection	9593524
127287602	127287625	6	+	27869803	HPAFII	viability after 27 days	GAACTGATCGATCAGTAGCAGGG	RNF146	ENSG00000118518	-0.42238518487551957	[110]	[42,43,NaN]	-3	hSpCas9	negative selection	9593525
127287604	127287627	6	+	27869803	HPAFII	viability after 27 days	ACTGATCGATCAGTAGCAGGGGG	RNF146	ENSG00000118518	-0.14907751415370463	[64]	[38,23,NaN]	-1	hSpCas9	negative selection	9593526
127286801	127286824	6	+	27869803	HPAFII	viability after 15 days	GAGCTTCATGGCTTGGAAAGCGG	RNF146	ENSG00000118518	0.6084233222910176	[352]	[919,365,NaN]	7	hSpCas9	negative selection	9675970
127286832	127286855	6	+	27869803	HPAFII	viability after 15 days	TTGTCGACAAGAAATTCCCGAGG	RNF146	ENSG00000118518	-0.17378707404696248	[668]	[785,544,NaN]	-2	hSpCas9	negative selection	9675971
127286873	127286896	6	-	27869803	HPAFII	viability after 15 days	GAGTTCTTCTGGTGACAACAAGG	RNF146	ENSG00000118518	0.41660468066505224	[143]	[266,168,NaN]	5	hSpCas9	negative selection	9675972
127287217	127287240	6	+	27869803	HPAFII	viability after 15 days	GACAGTGTATCAGCACAGAGTGG	RNF146	ENSG00000118518	0.4615464104615247	[235]	[294,382,NaN]	5	hSpCas9	negative selection	9675973
127287602	127287625	6	+	27869803	HPAFII	viability after 15 days	GAACTGATCGATCAGTAGCAGGG	RNF146	ENSG00000118518	-0.36483340535349584	[110]	[157,51,NaN]	-4	hSpCas9	negative selection	9675974
127287604	127287627	6	+	27869803	HPAFII	viability after 15 days	ACTGATCGATCAGTAGCAGGGGG	RNF146	ENSG00000118518	-0.4393467163871412	[64]	[61,44,NaN]	-5	hSpCas9	negative selection	9675975
127286801	127286824	6	+	27869803	ASPC1	viability after 36 days	GAGCTTCATGGCTTGGAAAGCGG	RNF146	ENSG00000118518	-0.6571697346048182	[1050]	[235,336,144]	-6	hSpCas9	negative selection	9758419
127286832	127286855	6	+	27869803	ASPC1	viability after 36 days	TTGTCGACAAGAAATTCCCGAGG	RNF146	ENSG00000118518	-1.5406668590322425	[1434]	[202,254,82]	-8	hSpCas9	negative selection	9758420
127286873	127286896	6	-	27869803	ASPC1	viability after 36 days	GAGTTCTTCTGGTGACAACAAGG	RNF146	ENSG00000118518	-0.05733211669631855	[475]	[67,309,102]	0	hSpCas9	negative selection	9758421
127287217	127287240	6	+	27869803	ASPC1	viability after 36 days	GACAGTGTATCAGCACAGAGTGG	RNF146	ENSG00000118518	-1.4148335370088099	[536]	[73,34,94]	-8	hSpCas9	negative selection	9758422
127287602	127287625	6	+	27869803	ASPC1	viability after 36 days	GAACTGATCGATCAGTAGCAGGG	RNF146	ENSG00000118518	1.7638494994446452	[415]	[294,1224,45]	9	hSpCas9	negative selection	9758423
127287604	127287627	6	+	27869803	ASPC1	viability after 36 days	ACTGATCGATCAGTAGCAGGGGG	RNF146	ENSG00000118518	-0.9059934153158569	[288]	[130,19,25]	-7	hSpCas9	negative selection	9758424
127286801	127286824	6	+	27869803	PATU8988S	viability after 35 days	GAGCTTCATGGCTTGGAAAGCGG	RNF146	ENSG00000118518	-0.7719603885346149	[1008]	[229,245,NaN]	-6	hSpCas9	negative selection	9840868
127286832	127286855	6	+	27869803	PATU8988S	viability after 35 days	TTGTCGACAAGAAATTCCCGAGG	RNF146	ENSG00000118518	-0.5188153974420462	[1032]	[234,345,NaN]	-5	hSpCas9	negative selection	9840869
127286873	127286896	6	-	27869803	PATU8988S	viability after 35 days	GAGTTCTTCTGGTGACAACAAGG	RNF146	ENSG00000118518	-0.7647996403290818	[313]	[42,105,NaN]	-6	hSpCas9	negative selection	9840870
127287217	127287240	6	+	27869803	PATU8988S	viability after 35 days	GACAGTGTATCAGCACAGAGTGG	RNF146	ENSG00000118518	0.055640434740174854	[527]	[226,214,NaN]	0	hSpCas9	negative selection	9840871
127287602	127287625	6	+	27869803	PATU8988S	viability after 35 days	GAACTGATCGATCAGTAGCAGGG	RNF146	ENSG00000118518	0.39577435363354546	[317]	[168,167,NaN]	4	hSpCas9	negative selection	9840872
127287604	127287627	6	+	27869803	PATU8988S	viability after 35 days	ACTGATCGATCAGTAGCAGGGGG	RNF146	ENSG00000118518	0.02979348687590222	[146]	[33,86,NaN]	0	hSpCas9	negative selection	9840873
127286801	127286824	6	+	27869803	PATU8988S	viability after 31 days	GAGCTTCATGGCTTGGAAAGCGG	RNF146	ENSG00000118518	-0.8058289818383552	[1008]	[168,307,NaN]	-7	hSpCas9	negative selection	9923317
127286832	127286855	6	+	27869803	PATU8988S	viability after 31 days	TTGTCGACAAGAAATTCCCGAGG	RNF146	ENSG00000118518	-0.4838058198056708	[1032]	[228,377,NaN]	-5	hSpCas9	negative selection	9923318
127286873	127286896	6	-	27869803	PATU8988S	viability after 31 days	GAGTTCTTCTGGTGACAACAAGG	RNF146	ENSG00000118518	-0.12118501477079435	[313]	[104,127,NaN]	-1	hSpCas9	negative selection	9923319
127287217	127287240	6	+	27869803	PATU8988S	viability after 31 days	GACAGTGTATCAGCACAGAGTGG	RNF146	ENSG00000118518	0.145500834895063	[527]	[220,247,NaN]	1	hSpCas9	negative selection	9923320
127287602	127287625	6	+	27869803	PATU8988S	viability after 31 days	GAACTGATCGATCAGTAGCAGGG	RNF146	ENSG00000118518	0.528604603766939	[317]	[152,220,NaN]	6	hSpCas9	negative selection	9923321
127287604	127287627	6	+	27869803	PATU8988S	viability after 31 days	ACTGATCGATCAGTAGCAGGGGG	RNF146	ENSG00000118518	0.08194061082937898	[146]	[65,56,NaN]	1	hSpCas9	negative selection	9923322
127286801	127286824	6	+	27869803	HPAFII	viability after 35 days	GAGCTTCATGGCTTGGAAAGCGG	RNF146	ENSG00000118518	1.029738671023515	[352]	[544,161,NaN]	7	hSpCas9	negative selection	10005766
127286832	127286855	6	+	27869803	HPAFII	viability after 35 days	TTGTCGACAAGAAATTCCCGAGG	RNF146	ENSG00000118518	-0.6054333250759608	[668]	[136,318,NaN]	-4	hSpCas9	negative selection	10005767
127286873	127286896	6	-	27869803	HPAFII	viability after 35 days	GAGTTCTTCTGGTGACAACAAGG	RNF146	ENSG00000118518	1.1279843491510577	[143]	[100,224,NaN]	7	hSpCas9	negative selection	10005768
127287217	127287240	6	+	27869803	HPAFII	viability after 35 days	GACAGTGTATCAGCACAGAGTGG	RNF146	ENSG00000118518	0.4381334484293337	[235]	[135,190,NaN]	3	hSpCas9	negative selection	10005769
127287602	127287625	6	+	27869803	HPAFII	viability after 35 days	GAACTGATCGATCAGTAGCAGGG	RNF146	ENSG00000118518	-0.6401864331899862	[110]	[28,43,NaN]	-4	hSpCas9	negative selection	10005770
127287604	127287627	6	+	27869803	HPAFII	viability after 35 days	ACTGATCGATCAGTAGCAGGGGG	RNF146	ENSG00000118518	-1.9679903992249002	[64]	[6,9,NaN]	-7	hSpCas9	negative selection	10005771
127286801	127286824	6	+	27869803	HPAFII	viability after 31 days	GAGCTTCATGGCTTGGAAAGCGG	RNF146	ENSG00000118518	1.0560221602903574	[352]	[554,255,NaN]	7	hSpCas9	negative selection	10088215
127286832	127286855	6	+	27869803	HPAFII	viability after 31 days	TTGTCGACAAGAAATTCCCGAGG	RNF146	ENSG00000118518	-0.6035817047478573	[668]	[237,256,NaN]	-4	hSpCas9	negative selection	10088216
127286873	127286896	6	-	27869803	HPAFII	viability after 31 days	GAGTTCTTCTGGTGACAACAAGG	RNF146	ENSG00000118518	0.8915777274674958	[143]	[125,175,NaN]	6	hSpCas9	negative selection	10088217
127287217	127287240	6	+	27869803	HPAFII	viability after 31 days	GACAGTGTATCAGCACAGAGTGG	RNF146	ENSG00000118518	0.6982018696856662	[235]	[111,326,NaN]	5	hSpCas9	negative selection	10088218
127287602	127287625	6	+	27869803	HPAFII	viability after 31 days	GAACTGATCGATCAGTAGCAGGG	RNF146	ENSG00000118518	0.11790667471997374	[110]	[80,52,NaN]	0	hSpCas9	negative selection	10088219
127287604	127287627	6	+	27869803	HPAFII	viability after 31 days	ACTGATCGATCAGTAGCAGGGGG	RNF146	ENSG00000118518	-2.097901302602936	[64]	[8,7,NaN]	-8	hSpCas9	negative selection	10088220
127287316	127287339	6	-	28162770	P31FUJ	viability	GAAGTGCTTGCATCAGGGGATGG	RNF146	ENSG00000118518	-0.3640467376926313	[68]	[62]	-3	hSpCas9	negative selection	10226185
127287422	127287445	6	+	28162770	P31FUJ	viability	ATGAATCACCATCTTCAGGCAGG	RNF146	ENSG00000118518	0.36680707227117915	[195]	[296]	4	hSpCas9	negative selection	10226186
127286832	127286855	6	+	28162770	P31FUJ	viability	TTGTCGACAAGAAATTCCCGAGG	RNF146	ENSG00000118518	0.7820455599929347	[144]	[292]	8	hSpCas9	negative selection	10226187
127286890	127286913	6	+	28162770	P31FUJ	viability	GAACTCAAGGCAGCAAGTAGAGG	RNF146	ENSG00000118518	0.950968922894762	[264]	[601]	9	hSpCas9	negative selection	10226188
127286877	127286900	6	+	28162770	P31FUJ	viability	GTTGTCACCAGAAGAACTCAAGG	RNF146	ENSG00000118518	0.6772990465518669	[388]	[730]	7	hSpCas9	negative selection	10226189
127287388	127287411	6	+	28162770	P31FUJ	viability	GAAAGGAGTCATAGGGGAGAAGG	RNF146	ENSG00000118518	0.14258621821146525	[248]	[322]	1	hSpCas9	negative selection	10226190
127286967	127286990	6	+	28162770	P31FUJ	viability	TGAGCGCACTAGTAGAGAGCTGG	RNF146	ENSG00000118518	0.9681848533187984	[193]	[445]	9	hSpCas9	negative selection	10226191
127287190	127287213	6	+	28162770	P31FUJ	viability	GCAAGAGAGAGCTCTGCTGACGG	RNF146	ENSG00000118518	-0.051757253971182915	[358]	[406]	0	hSpCas9	negative selection	10226192
127287217	127287240	6	+	28162770	P31FUJ	viability	GACAGTGTATCAGCACAGAGTGG	RNF146	ENSG00000118518	0.8020395447979222	[224]	[460]	8	hSpCas9	negative selection	10226193
127287253	127287276	6	-	28162770	P31FUJ	viability	GGCCTTACAGAAGACACTAGGGG	RNF146	ENSG00000118518	-0.12177089202563485	[99]	[107]	-1	hSpCas9	negative selection	10226194
127287316	127287339	6	-	28162770	TF1	viability	GAAGTGCTTGCATCAGGGGATGG	RNF146	ENSG00000118518	NaN	[NaN]	[48]	1	hSpCas9	negative selection	10395551
127287422	127287445	6	+	28162770	TF1	viability	ATGAATCACCATCTTCAGGCAGG	RNF146	ENSG00000118518	NaN	[NaN]	[304]	1	hSpCas9	negative selection	10395552
127286832	127286855	6	+	28162770	TF1	viability	TTGTCGACAAGAAATTCCCGAGG	RNF146	ENSG00000118518	NaN	[NaN]	[132]	1	hSpCas9	negative selection	10395553
127286890	127286913	6	+	28162770	TF1	viability	GAACTCAAGGCAGCAAGTAGAGG	RNF146	ENSG00000118518	NaN	[NaN]	[437]	1	hSpCas9	negative selection	10395554
127286877	127286900	6	+	28162770	TF1	viability	GTTGTCACCAGAAGAACTCAAGG	RNF146	ENSG00000118518	NaN	[NaN]	[265]	1	hSpCas9	negative selection	10395555
127287388	127287411	6	+	28162770	TF1	viability	GAAAGGAGTCATAGGGGAGAAGG	RNF146	ENSG00000118518	NaN	[NaN]	[230]	1	hSpCas9	negative selection	10395556
127286967	127286990	6	+	28162770	TF1	viability	TGAGCGCACTAGTAGAGAGCTGG	RNF146	ENSG00000118518	NaN	[NaN]	[76]	1	hSpCas9	negative selection	10395557
127287190	127287213	6	+	28162770	TF1	viability	GCAAGAGAGAGCTCTGCTGACGG	RNF146	ENSG00000118518	NaN	[NaN]	[243]	1	hSpCas9	negative selection	10395558
127287217	127287240	6	+	28162770	TF1	viability	GACAGTGTATCAGCACAGAGTGG	RNF146	ENSG00000118518	NaN	[NaN]	[194]	1	hSpCas9	negative selection	10395559
127287253	127287276	6	-	28162770	TF1	viability	GGCCTTACAGAAGACACTAGGGG	RNF146	ENSG00000118518	NaN	[NaN]	[33]	1	hSpCas9	negative selection	10395560
127287316	127287339	6	-	28162770	SKM1	viability	GAAGTGCTTGCATCAGGGGATGG	RNF146	ENSG00000118518	0.6227831446508902	[17]	[48]	6	hSpCas9	negative selection	10564917
127287422	127287445	6	+	28162770	SKM1	viability	ATGAATCACCATCTTCAGGCAGG	RNF146	ENSG00000118518	0.4093238480844501	[45]	[107]	4	hSpCas9	negative selection	10564918
127286832	127286855	6	+	28162770	SKM1	viability	TTGTCGACAAGAAATTCCCGAGG	RNF146	ENSG00000118518	-0.8220016980220055	[43]	[43]	-6	hSpCas9	negative selection	10564919
127286890	127286913	6	+	28162770	SKM1	viability	GAACTCAAGGCAGCAAGTAGAGG	RNF146	ENSG00000118518	0.028988352844927845	[106]	[192]	0	hSpCas9	negative selection	10564920
127286877	127286900	6	+	28162770	SKM1	viability	GTTGTCACCAGAAGAACTCAAGG	RNF146	ENSG00000118518	0.4939026092375868	[95]	[238]	5	hSpCas9	negative selection	10564921
127287388	127287411	6	+	28162770	SKM1	viability	GAAAGGAGTCATAGGGGAGAAGG	RNF146	ENSG00000118518	0.9505878058749221	[95]	[327]	8	hSpCas9	negative selection	10564922
127286967	127286990	6	+	28162770	SKM1	viability	TGAGCGCACTAGTAGAGAGCTGG	RNF146	ENSG00000118518	0.7294082429881239	[28]	[84]	7	hSpCas9	negative selection	10564923
127287190	127287213	6	+	28162770	SKM1	viability	GCAAGAGAGAGCTCTGCTGACGG	RNF146	ENSG00000118518	0.23689199103156283	[71]	[149]	2	hSpCas9	negative selection	10564924
127287217	127287240	6	+	28162770	SKM1	viability	GACAGTGTATCAGCACAGAGTGG	RNF146	ENSG00000118518	0.17799830197799468	[56]	[113]	1	hSpCas9	negative selection	10564925
127287253	127287276	6	-	28162770	SKM1	viability	GGCCTTACAGAAGACACTAGGGG	RNF146	ENSG00000118518	0.025995208532944458	[19]	[35]	0	hSpCas9	negative selection	10564926
127287316	127287339	6	-	28162770	SKM1	viability	GAAGTGCTTGCATCAGGGGATGG	RNF146	ENSG00000118518	0.6227831446508902	[17]	[48]	6	hSpCas9	negative selection	10734283
127287422	127287445	6	+	28162770	SKM1	viability	ATGAATCACCATCTTCAGGCAGG	RNF146	ENSG00000118518	0.4093238480844501	[45]	[107]	4	hSpCas9	negative selection	10734284
127286832	127286855	6	+	28162770	SKM1	viability	TTGTCGACAAGAAATTCCCGAGG	RNF146	ENSG00000118518	-0.8220016980220055	[43]	[43]	-6	hSpCas9	negative selection	10734285
127286890	127286913	6	+	28162770	SKM1	viability	GAACTCAAGGCAGCAAGTAGAGG	RNF146	ENSG00000118518	0.028988352844927845	[106]	[192]	0	hSpCas9	negative selection	10734286
127286877	127286900	6	+	28162770	SKM1	viability	GTTGTCACCAGAAGAACTCAAGG	RNF146	ENSG00000118518	0.4939026092375868	[95]	[238]	5	hSpCas9	negative selection	10734287
127287388	127287411	6	+	28162770	SKM1	viability	GAAAGGAGTCATAGGGGAGAAGG	RNF146	ENSG00000118518	0.9505878058749221	[95]	[327]	8	hSpCas9	negative selection	10734288
127286967	127286990	6	+	28162770	SKM1	viability	TGAGCGCACTAGTAGAGAGCTGG	RNF146	ENSG00000118518	0.7294082429881239	[28]	[84]	7	hSpCas9	negative selection	10734289
127287190	127287213	6	+	28162770	SKM1	viability	GCAAGAGAGAGCTCTGCTGACGG	RNF146	ENSG00000118518	0.23689199103156283	[71]	[149]	2	hSpCas9	negative selection	10734290
127287217	127287240	6	+	28162770	SKM1	viability	GACAGTGTATCAGCACAGAGTGG	RNF146	ENSG00000118518	0.17799830197799468	[56]	[113]	1	hSpCas9	negative selection	10734291
127287253	127287276	6	-	28162770	SKM1	viability	GGCCTTACAGAAGACACTAGGGG	RNF146	ENSG00000118518	0.025995208532944458	[19]	[35]	0	hSpCas9	negative selection	10734292
127287316	127287339	6	-	28162770	PL21	viability	GAAGTGCTTGCATCAGGGGATGG	RNF146	ENSG00000118518	0.2311665101099447	[91]	[46]	2	hSpCas9	negative selection	10903649
127287422	127287445	6	+	28162770	PL21	viability	ATGAATCACCATCTTCAGGCAGG	RNF146	ENSG00000118518	0.43783117220865053	[133]	[78]	4	hSpCas9	negative selection	10903650
127286832	127286855	6	+	28162770	PL21	viability	TTGTCGACAAGAAATTCCCGAGG	RNF146	ENSG00000118518	-0.14089730334574685	[151]	[59]	-1	hSpCas9	negative selection	10903651
127286890	127286913	6	+	28162770	PL21	viability	GAACTCAAGGCAGCAAGTAGAGG	RNF146	ENSG00000118518	0.233498211435751	[341]	[174]	2	hSpCas9	negative selection	10903652
127286877	127286900	6	+	28162770	PL21	viability	GTTGTCACCAGAAGAACTCAAGG	RNF146	ENSG00000118518	-0.06801722395706156	[394]	[163]	0	hSpCas9	negative selection	10903653
127287388	127287411	6	+	28162770	PL21	viability	GAAAGGAGTCATAGGGGAGAAGG	RNF146	ENSG00000118518	-0.40594617779758985	[343]	[112]	-3	hSpCas9	negative selection	10903654
127286967	127286990	6	+	28162770	PL21	viability	TGAGCGCACTAGTAGAGAGCTGG	RNF146	ENSG00000118518	0.2716928755143543	[117]	[61]	2	hSpCas9	negative selection	10903655
127287190	127287213	6	+	28162770	PL21	viability	GCAAGAGAGAGCTCTGCTGACGG	RNF146	ENSG00000118518	-1.1408973033457468	[303]	[59]	-6	hSpCas9	negative selection	10903656
127287217	127287240	6	+	28162770	PL21	viability	GACAGTGTATCAGCACAGAGTGG	RNF146	ENSG00000118518	-0.651761746521546	[147]	[40]	-4	hSpCas9	negative selection	10903657
127287253	127287276	6	-	28162770	PL21	viability	GGCCTTACAGAAGACACTAGGGG	RNF146	ENSG00000118518	-0.028129373183797046	[81]	[34]	0	hSpCas9	negative selection	10903658
127287316	127287339	6	-	28162770	P31FUJ	viability	GAAGTGCTTGCATCAGGGGATGG	RNF146	ENSG00000118518	-0.3640467376926313	[68]	[62]	-3	hSpCas9	negative selection	11073015
127287422	127287445	6	+	28162770	P31FUJ	viability	ATGAATCACCATCTTCAGGCAGG	RNF146	ENSG00000118518	0.36680707227117915	[195]	[296]	4	hSpCas9	negative selection	11073016
127286832	127286855	6	+	28162770	P31FUJ	viability	TTGTCGACAAGAAATTCCCGAGG	RNF146	ENSG00000118518	0.7820455599929347	[144]	[292]	8	hSpCas9	negative selection	11073017
127286890	127286913	6	+	28162770	P31FUJ	viability	GAACTCAAGGCAGCAAGTAGAGG	RNF146	ENSG00000118518	0.950968922894762	[264]	[601]	9	hSpCas9	negative selection	11073018
127286877	127286900	6	+	28162770	P31FUJ	viability	GTTGTCACCAGAAGAACTCAAGG	RNF146	ENSG00000118518	0.6772990465518669	[388]	[730]	7	hSpCas9	negative selection	11073019
127287388	127287411	6	+	28162770	P31FUJ	viability	GAAAGGAGTCATAGGGGAGAAGG	RNF146	ENSG00000118518	0.14258621821146525	[248]	[322]	1	hSpCas9	negative selection	11073020
127286967	127286990	6	+	28162770	P31FUJ	viability	TGAGCGCACTAGTAGAGAGCTGG	RNF146	ENSG00000118518	0.9681848533187984	[193]	[445]	9	hSpCas9	negative selection	11073021
127287190	127287213	6	+	28162770	P31FUJ	viability	GCAAGAGAGAGCTCTGCTGACGG	RNF146	ENSG00000118518	-0.051757253971182915	[358]	[406]	0	hSpCas9	negative selection	11073022
127287217	127287240	6	+	28162770	P31FUJ	viability	GACAGTGTATCAGCACAGAGTGG	RNF146	ENSG00000118518	0.8020395447979222	[224]	[460]	8	hSpCas9	negative selection	11073023
127287253	127287276	6	-	28162770	P31FUJ	viability	GGCCTTACAGAAGACACTAGGGG	RNF146	ENSG00000118518	-0.12177089202563485	[99]	[107]	-1	hSpCas9	negative selection	11073024
127287316	127287339	6	-	28162770	OCIAML5	viability	GAAGTGCTTGCATCAGGGGATGG	RNF146	ENSG00000118518	0.7853633497512947	[35]	[111]	7	hSpCas9	negative selection	11242381
127287422	127287445	6	+	28162770	OCIAML5	viability	ATGAATCACCATCTTCAGGCAGG	RNF146	ENSG00000118518	-0.2224350208091124	[158]	[245]	-2	hSpCas9	negative selection	11242382
127286832	127286855	6	+	28162770	OCIAML5	viability	TTGTCGACAAGAAATTCCCGAGG	RNF146	ENSG00000118518	0.906115509211905	[80]	[273]	7	hSpCas9	negative selection	11242383
127286890	127286913	6	+	28162770	OCIAML5	viability	GAACTCAAGGCAGCAAGTAGAGG	RNF146	ENSG00000118518	0.25424233128234364	[169]	[365]	2	hSpCas9	negative selection	11242384
127286877	127286900	6	+	28162770	OCIAML5	viability	GTTGTCACCAGAAGAACTCAAGG	RNF146	ENSG00000118518	0.9592718651121048	[154]	[543]	8	hSpCas9	negative selection	11242385
127287388	127287411	6	+	28162770	OCIAML5	viability	GAAAGGAGTCATAGGGGAGAAGG	RNF146	ENSG00000118518	0.9770488699324179	[140]	[500]	8	hSpCas9	negative selection	11242386
127286967	127286990	6	+	28162770	OCIAML5	viability	TGAGCGCACTAGTAGAGAGCTGG	RNF146	ENSG00000118518	0.6530426221679446	[129]	[368]	6	hSpCas9	negative selection	11242387
127287190	127287213	6	+	28162770	OCIAML5	viability	GCAAGAGAGAGCTCTGCTGACGG	RNF146	ENSG00000118518	-0.023280268274881832	[209]	[372]	0	hSpCas9	negative selection	11242388
127287217	127287240	6	+	28162770	OCIAML5	viability	GACAGTGTATCAGCACAGAGTGG	RNF146	ENSG00000118518	-0.17303574578193226	[187]	[300]	-1	hSpCas9	negative selection	11242389
127287253	127287276	6	-	28162770	OCIAML5	viability	GGCCTTACAGAAGACACTAGGGG	RNF146	ENSG00000118518	0.6298024368930555	[57]	[161]	5	hSpCas9	negative selection	11242390
127287316	127287339	6	-	28162770	EOL1	viability	GAAGTGCTTGCATCAGGGGATGG	RNF146	ENSG00000118518	0.32447837845917005	[143]	[94]	3	hSpCas9	negative selection	11411747
127287422	127287445	6	+	28162770	EOL1	viability	ATGAATCACCATCTTCAGGCAGG	RNF146	ENSG00000118518	0.36591941866284095	[189]	[128]	3	hSpCas9	negative selection	11411748
127286832	127286855	6	+	28162770	EOL1	viability	TTGTCGACAAGAAATTCCCGAGG	RNF146	ENSG00000118518	0.8606360077503413	[299]	[286]	7	hSpCas9	negative selection	11411749
127286890	127286913	6	+	28162770	EOL1	viability	GAACTCAAGGCAGCAAGTAGAGG	RNF146	ENSG00000118518	0.02153338693938056	[603]	[322]	0	hSpCas9	negative selection	11411750
127286877	127286900	6	+	28162770	EOL1	viability	GTTGTCACCAGAAGAACTCAAGG	RNF146	ENSG00000118518	0.3165385340873108	[630]	[413]	3	hSpCas9	negative selection	11411751
127287388	127287411	6	+	28162770	EOL1	viability	GAAAGGAGTCATAGGGGAGAAGG	RNF146	ENSG00000118518	-0.23922022908172502	[642]	[286]	-2	hSpCas9	negative selection	11411752
127286967	127286990	6	+	28162770	EOL1	viability	TGAGCGCACTAGTAGAGAGCTGG	RNF146	ENSG00000118518	-0.67061049625651	[141]	[46]	-5	hSpCas9	negative selection	11411753
127287190	127287213	6	+	28162770	EOL1	viability	GCAAGAGAGAGCTCTGCTGACGG	RNF146	ENSG00000118518	0.17682148256654426	[313]	[186]	1	hSpCas9	negative selection	11411754
127287217	127287240	6	+	28162770	EOL1	viability	GACAGTGTATCAGCACAGAGTGG	RNF146	ENSG00000118518	0.6452640140916659	[249]	[205]	6	hSpCas9	negative selection	11411755
127287253	127287276	6	-	28162770	EOL1	viability	GGCCTTACAGAAGACACTAGGGG	RNF146	ENSG00000118518	0.5375246484612874	[84]	[64]	5	hSpCas9	negative selection	11411756
127287316	127287339	6	-	28162770	MOLM13	viability	GAAGTGCTTGCATCAGGGGATGG	RNF146	ENSG00000118518	0.2584360159156289	[110]	[95]	1	hSpCas9	negative selection	11581113
127287422	127287445	6	+	28162770	MOLM13	viability	ATGAATCACCATCTTCAGGCAGG	RNF146	ENSG00000118518	-0.18201185087689797	[283]	[180]	-1	hSpCas9	negative selection	11581114
127286832	127286855	6	+	28162770	MOLM13	viability	TTGTCGACAAGAAATTCCCGAGG	RNF146	ENSG00000118518	-0.6670401985415296	[223]	[101]	-4	hSpCas9	negative selection	11581115
127286890	127286913	6	+	28162770	MOLM13	viability	GAACTCAAGGCAGCAAGTAGAGG	RNF146	ENSG00000118518	-0.39301500878975937	[493]	[271]	-2	hSpCas9	negative selection	11581116
127286877	127286900	6	+	28162770	MOLM13	viability	GTTGTCACCAGAAGAACTCAAGG	RNF146	ENSG00000118518	0.7522579290572488	[536]	[653]	6	hSpCas9	negative selection	11581117
127287388	127287411	6	+	28162770	MOLM13	viability	GAAAGGAGTCATAGGGGAGAAGG	RNF146	ENSG00000118518	0.9528288940535787	[422]	[591]	7	hSpCas9	negative selection	11581118
127286967	127286990	6	+	28162770	MOLM13	viability	TGAGCGCACTAGTAGAGAGCTGG	RNF146	ENSG00000118518	-0.21380890597400823	[238]	[148]	-1	hSpCas9	negative selection	11581119
127287190	127287213	6	+	28162770	MOLM13	viability	GCAAGAGAGAGCTCTGCTGACGG	RNF146	ENSG00000118518	-1.0394522220541034	[397]	[139]	-5	hSpCas9	negative selection	11581120
127287217	127287240	6	+	28162770	MOLM13	viability	GACAGTGTATCAGCACAGAGTGG	RNF146	ENSG00000118518	0.05463850173974957	[268]	[201]	0	hSpCas9	negative selection	11581121
127287253	127287276	6	-	28162770	MOLM13	viability	GGCCTTACAGAAGACACTAGGGG	RNF146	ENSG00000118518	0.20291717146929245	[148]	[123]	1	hSpCas9	negative selection	11581122
127287316	127287339	6	-	28162770	HEL	viability	GAAGTGCTTGCATCAGGGGATGG	RNF146	ENSG00000118518	0.5525410230287789	[131]	[123]	5	hSpCas9	negative selection	11750479
127287422	127287445	6	+	28162770	HEL	viability	ATGAATCACCATCTTCAGGCAGG	RNF146	ENSG00000118518	-0.02920697031543923	[187]	[117]	0	hSpCas9	negative selection	11750480
127286832	127286855	6	+	28162770	HEL	viability	TTGTCGACAAGAAATTCCCGAGG	RNF146	ENSG00000118518	0.48026413504325155	[168]	[150]	4	hSpCas9	negative selection	11750481
127286890	127286913	6	+	28162770	HEL	viability	GAACTCAAGGCAGCAAGTAGAGG	RNF146	ENSG00000118518	-0.7887757128205913	[498]	[184]	-5	hSpCas9	negative selection	11750482
127286877	127286900	6	+	28162770	HEL	viability	GTTGTCACCAGAAGAACTCAAGG	RNF146	ENSG00000118518	0.08441145778266768	[482]	[327]	0	hSpCas9	negative selection	11750483
127287388	127287411	6	+	28162770	HEL	viability	GAAAGGAGTCATAGGGGAGAAGG	RNF146	ENSG00000118518	0.33131402353225714	[478]	[385]	2	hSpCas9	negative selection	11750484
127286967	127286990	6	+	28162770	HEL	viability	TGAGCGCACTAGTAGAGAGCTGG	RNF146	ENSG00000118518	-0.27925865599836985	[179]	[94]	-2	hSpCas9	negative selection	11750485
127287190	127287213	6	+	28162770	HEL	viability	GCAAGAGAGAGCTCTGCTGACGG	RNF146	ENSG00000118518	-0.8937251510296091	[350]	[120]	-5	hSpCas9	negative selection	11750486
127287217	127287240	6	+	28162770	HEL	viability	GACAGTGTATCAGCACAGAGTGG	RNF146	ENSG00000118518	-0.35138460166297375	[244]	[122]	-2	hSpCas9	negative selection	11750487
127287253	127287276	6	-	28162770	HEL	viability	GGCCTTACAGAAGACACTAGGGG	RNF146	ENSG00000118518	-0.7108981226143434	[91]	[35]	-4	hSpCas9	negative selection	11750488
127287316	127287339	6	-	28162770	MV411	viability	GAAGTGCTTGCATCAGGGGATGG	RNF146	ENSG00000118518	-0.09359936705229166	[75]	[59]	0	hSpCas9	negative selection	11919845
127287422	127287445	6	+	28162770	MV411	viability	ATGAATCACCATCTTCAGGCAGG	RNF146	ENSG00000118518	1.539523634141212	[126]	[310]	9	hSpCas9	negative selection	11919846
127286832	127286855	6	+	28162770	MV411	viability	TTGTCGACAAGAAATTCCCGAGG	RNF146	ENSG00000118518	0.18854386172920692	[174]	[167]	1	hSpCas9	negative selection	11919847
127286890	127286913	6	+	28162770	MV411	viability	GAACTCAAGGCAGCAAGTAGAGG	RNF146	ENSG00000118518	0.07751254934046292	[305]	[271]	0	hSpCas9	negative selection	11919848
127286877	127286900	6	+	28162770	MV411	viability	GTTGTCACCAGAAGAACTCAAGG	RNF146	ENSG00000118518	0.5254628237933225	[366]	[444]	5	hSpCas9	negative selection	11919849
127287388	127287411	6	+	28162770	MV411	viability	GAAAGGAGTCATAGGGGAGAAGG	RNF146	ENSG00000118518	0.5365342532027652	[319]	[390]	5	hSpCas9	negative selection	11919850
127286967	127286990	6	+	28162770	MV411	viability	TGAGCGCACTAGTAGAGAGCTGG	RNF146	ENSG00000118518	1.0569156447333492	[96]	[169]	8	hSpCas9	negative selection	11919851
127287190	127287213	6	+	28162770	MV411	viability	GCAAGAGAGAGCTCTGCTGACGG	RNF146	ENSG00000118518	-0.171275606639467	[261]	[195]	-1	hSpCas9	negative selection	11919852
127287217	127287240	6	+	28162770	MV411	viability	GACAGTGTATCAGCACAGAGTGG	RNF146	ENSG00000118518	-0.3757081438262689	[133]	[86]	-3	hSpCas9	negative selection	11919853
127287253	127287276	6	-	28162770	MV411	viability	GGCCTTACAGAAGACACTAGGGG	RNF146	ENSG00000118518	0.6405824442127769	[82]	[108]	6	hSpCas9	negative selection	11919854
127287316	127287339	6	-	28162770	MONOMAC1	viability	GAAGTGCTTGCATCAGGGGATGG	RNF146	ENSG00000118518	-0.6215346755874638	[50]	[37]	-5	hSpCas9	negative selection	12089211
127287422	127287445	6	+	28162770	MONOMAC1	viability	ATGAATCACCATCTTCAGGCAGG	RNF146	ENSG00000118518	0.07758553304945204	[61]	[74]	0	hSpCas9	negative selection	12089212
127286832	127286855	6	+	28162770	MONOMAC1	viability	TTGTCGACAAGAAATTCCCGAGG	RNF146	ENSG00000118518	0.3175363257702045	[146]	[209]	3	hSpCas9	negative selection	12089213
127286890	127286913	6	+	28162770	MONOMAC1	viability	GAACTCAAGGCAGCAAGTAGAGG	RNF146	ENSG00000118518	1.0798033582992705	[181]	[440]	8	hSpCas9	negative selection	12089214
127286877	127286900	6	+	28162770	MONOMAC1	viability	GTTGTCACCAGAAGAACTCAAGG	RNF146	ENSG00000118518	0.9344679360689383	[240]	[527]	8	hSpCas9	negative selection	12089215
127287388	127287411	6	+	28162770	MONOMAC1	viability	GAAAGGAGTCATAGGGGAGAAGG	RNF146	ENSG00000118518	0.15088645636075315	[186]	[237]	1	hSpCas9	negative selection	12089216
127286967	127286990	6	+	28162770	MONOMAC1	viability	TGAGCGCACTAGTAGAGAGCTGG	RNF146	ENSG00000118518	0.38263135399208936	[90]	[135]	4	hSpCas9	negative selection	12089217
127287190	127287213	6	+	28162770	MONOMAC1	viability	GCAAGAGAGAGCTCTGCTGACGG	RNF146	ENSG00000118518	1.1923272583298592	[162]	[426]	9	hSpCas9	negative selection	12089218
127287217	127287240	6	+	28162770	MONOMAC1	viability	GACAGTGTATCAGCACAGAGTGG	RNF146	ENSG00000118518	-0.5720762784064786	[82]	[63]	-5	hSpCas9	negative selection	12089219
127287253	127287276	6	-	28162770	MONOMAC1	viability	GGCCTTACAGAAGACACTAGGGG	RNF146	ENSG00000118518	0.5914590477467345	[43]	[75]	6	hSpCas9	negative selection	12089220
127287316	127287339	6	-	28162770	OCIAML2	viability	GAAGTGCTTGCATCAGGGGATGG	RNF146	ENSG00000118518	-0.06853138167081574	[13]	[73]	0	hSpCas9	negative selection	12258577
127287422	127287445	6	+	28162770	OCIAML2	viability	ATGAATCACCATCTTCAGGCAGG	RNF146	ENSG00000118518	0.43626077036635735	[17]	[134]	4	hSpCas9	negative selection	12258578
127286832	127286855	6	+	28162770	OCIAML2	viability	TTGTCGACAAGAAATTCCCGAGG	RNF146	ENSG00000118518	-0.49434589421596875	[45]	[180]	-4	hSpCas9	negative selection	12258579
127286890	127286913	6	+	28162770	OCIAML2	viability	GAACTCAAGGCAGCAAGTAGAGG	RNF146	ENSG00000118518	0.2188886065215847	[50]	[328]	2	hSpCas9	negative selection	12258580
127286877	127286900	6	+	28162770	OCIAML2	viability	GTTGTCACCAGAAGAACTCAAGG	RNF146	ENSG00000118518	-0.09020608104465444	[57]	[301]	0	hSpCas9	negative selection	12258581
127287388	127287411	6	+	28162770	OCIAML2	viability	GAAAGGAGTCATAGGGGAGAAGG	RNF146	ENSG00000118518	0.4901995774771609	[55]	[435]	5	hSpCas9	negative selection	12258582
127286967	127286990	6	+	28162770	OCIAML2	viability	TGAGCGCACTAGTAGAGAGCTGG	RNF146	ENSG00000118518	0.1288322451741099	[32]	[199]	1	hSpCas9	negative selection	12258583
127287190	127287213	6	+	28162770	OCIAML2	viability	GCAAGAGAGAGCTCTGCTGACGG	RNF146	ENSG00000118518	0.2959394819689426	[40]	[278]	3	hSpCas9	negative selection	12258584
127287217	127287240	6	+	28162770	OCIAML2	viability	GACAGTGTATCAGCACAGAGTGG	RNF146	ENSG00000118518	0.005519188340069731	[38]	[216]	0	hSpCas9	negative selection	12258585
127287253	127287276	6	-	28162770	OCIAML2	viability	GGCCTTACAGAAGACACTAGGGG	RNF146	ENSG00000118518	-0.23359062794131202	[13]	[65]	-2	hSpCas9	negative selection	12258586
127287316	127287339	6	-	28162770	OCIAML3	viability	GAAGTGCTTGCATCAGGGGATGG	RNF146	ENSG00000118518	-0.3825035351304511	[18]	[43]	-3	hSpCas9	negative selection	12427943
127287422	127287445	6	+	28162770	OCIAML3	viability	ATGAATCACCATCTTCAGGCAGG	RNF146	ENSG00000118518	0.7430273469534076	[37]	[191]	6	hSpCas9	negative selection	12427944
127286832	127286855	6	+	28162770	OCIAML3	viability	TTGTCGACAAGAAATTCCCGAGG	RNF146	ENSG00000118518	0.07918204340872853	[36]	[117]	0	hSpCas9	negative selection	12427945
127286890	127286913	6	+	28162770	OCIAML3	viability	GAACTCAAGGCAGCAAGTAGAGG	RNF146	ENSG00000118518	0.42611395559661003	[88]	[360]	4	hSpCas9	negative selection	12427946
127286877	127286900	6	+	28162770	OCIAML3	viability	GTTGTCACCAGAAGAACTCAAGG	RNF146	ENSG00000118518	1.434789623983272	[92]	[758]	9	hSpCas9	negative selection	12427947
127287388	127287411	6	+	28162770	OCIAML3	viability	GAAAGGAGTCATAGGGGAGAAGG	RNF146	ENSG00000118518	0.4926467419300189	[104]	[445]	4	hSpCas9	negative selection	12427948
127286967	127286990	6	+	28162770	OCIAML3	viability	TGAGCGCACTAGTAGAGAGCTGG	RNF146	ENSG00000118518	0.2759318191114639	[28]	[105]	2	hSpCas9	negative selection	12427949
127287190	127287213	6	+	28162770	OCIAML3	viability	GCAAGAGAGAGCTCTGCTGACGG	RNF146	ENSG00000118518	-0.13103566398161737	[73]	[203]	-1	hSpCas9	negative selection	12427950
127287217	127287240	6	+	28162770	OCIAML3	viability	GACAGTGTATCAGCACAGAGTGG	RNF146	ENSG00000118518	-0.07721664224458613	[64]	[185]	0	hSpCas9	negative selection	12427951
127287253	127287276	6	-	28162770	OCIAML3	viability	GGCCTTACAGAAGACACTAGGGG	RNF146	ENSG00000118518	0.47638168756723465	[9]	[41]	4	hSpCas9	negative selection	12427952