| 2263083 | 2263106 | 16 | + | 26472758 | Jiyoye | viability | GCAGGGCACTCACTTGGAGCGGG | RNPS1 | ENSG00000205937 | -1.8526917452492375 | [181] | [37] | -8 | hSpCas9 | negative selection | 138765 | 2264208 | 2264231 | 16 | - | 26472758 | Jiyoye | viability | GCCGGGACAAAACCCGAAAGAGG | RNPS1 | ENSG00000205937 | 0.43465611792798065 | [51] | [52] | 3 | hSpCas9 | negative selection | 138766 | 2264560 | 2264583 | 16 | + | 26472758 | Jiyoye | viability | ACAGAAGGATTACCTAGTGCTGG | RNPS1 | ENSG00000205937 | -0.8548812574040906 | [294] | [122] | -5 | hSpCas9 | negative selection | 138767 | 2263194 | 2263217 | 16 | + | 26472758 | Jiyoye | viability | TCCTGAGCGGCTGGATGCTGAGG | RNPS1 | ENSG00000205937 | -0.537329505902423 | [101] | [52] | -4 | hSpCas9 | negative selection | 138768 | 2263083 | 2263106 | 16 | + | 26472758 | KBM7 | viability | GCAGGGCACTCACTTGGAGCGGG | RNPS1 | ENSG00000205937 | -1.8475406270978356 | [684,509] | [90,64] | -8 | hSpCas9 | negative selection | 329883 | 2264208 | 2264231 | 16 | - | 26472758 | KBM7 | viability | GCCGGGACAAAACCCGAAAGAGG | RNPS1 | ENSG00000205937 | -3.2886573524434577 | [313,156] | [10,10] | -9 | hSpCas9 | negative selection | 329884 | 2264560 | 2264583 | 16 | + | 26472758 | KBM7 | viability | ACAGAAGGATTACCTAGTGCTGG | RNPS1 | ENSG00000205937 | 0.017400120300754218 | [650,495] | [251,286] | 0 | hSpCas9 | negative selection | 329885 | 2263194 | 2263217 | 16 | + | 26472758 | KBM7 | viability | TCCTGAGCGGCTGGATGCTGAGG | RNPS1 | ENSG00000205937 | -1.8600982594811106 | [631,490] | [59,82] | -8 | hSpCas9 | negative selection | 329886 | 2263083 | 2263106 | 16 | + | 26472758 | Raji | viability | GCAGGGCACTCACTTGGAGCGGG | RNPS1 | ENSG00000205937 | -0.12478990675543386 | [295] | [62] | -1 | hSpCas9 | negative selection | 521001 | 2264208 | 2264231 | 16 | - | 26472758 | Raji | viability | GCCGGGACAAAACCCGAAAGAGG | RNPS1 | ENSG00000205937 | -1.0758382886821707 | [108] | [11] | -7 | hSpCas9 | negative selection | 521002 | 2264560 | 2264583 | 16 | + | 26472758 | Raji | viability | ACAGAAGGATTACCTAGTGCTGG | RNPS1 | ENSG00000205937 | 0.07803957379145532 | [297] | [72] | 0 | hSpCas9 | negative selection | 521003 | 2263194 | 2263217 | 16 | + | 26472758 | Raji | viability | TCCTGAGCGGCTGGATGCTGAGG | RNPS1 | ENSG00000205937 | -0.05795419657306111 | [313] | [69] | 0 | hSpCas9 | negative selection | 521004 | 2263083 | 2263106 | 16 | + | 26472758 | K562 | viability | GCAGGGCACTCACTTGGAGCGGG | RNPS1 | ENSG00000205937 | -2.2625412610534363 | [539] | [94] | -7 | hSpCas9 | negative selection | 712119 | 2264208 | 2264231 | 16 | - | 26472758 | K562 | viability | GCCGGGACAAAACCCGAAAGAGG | RNPS1 | ENSG00000205937 | -0.6195197227575246 | [181] | [99] | -4 | hSpCas9 | negative selection | 712120 | 2264560 | 2264583 | 16 | + | 26472758 | K562 | viability | ACAGAAGGATTACCTAGTGCTGG | RNPS1 | ENSG00000205937 | 0.37796905808642545 | [597] | [655] | 3 | hSpCas9 | negative selection | 712121 | 2263194 | 2263217 | 16 | + | 26472758 | K562 | viability | TCCTGAGCGGCTGGATGCTGAGG | RNPS1 | ENSG00000205937 | -0.4829608176705613 | [499] | [301] | -3 | hSpCas9 | negative selection | 712122 | 2263082 | 2263105 | 16 | + | 26627737 | DLD1 | viability | CGCAGGGCACTCACTTGGAGCGG | RNPS1 | ENSG00000205937 | -1.9056365586349076 | [1986] | [176,160,159] | -8 | hSpCas9 | negative selection | 793210 | 2263082 | 2263105 | 16 | + | 26627737 | GBM cells | viability after 5 days | CGCAGGGCACTCACTTGGAGCGG | RNPS1 | ENSG00000205937 | -0.02730819897476655 | [971] | [540,481] | 0 | hSpCas9 | negative selection | 875525 | 2263082 | 2263105 | 16 | + | 26627737 | GBM cells | viability after 13 days | CGCAGGGCACTCACTTGGAGCGG | RNPS1 | ENSG00000205937 | -0.28294355553244044 | [971] | [540,345] | -3 | hSpCas9 | negative selection | 957840 | 2263082 | 2263105 | 16 | + | 26627737 | GBM cells | viability after 21 days | CGCAGGGCACTCACTTGGAGCGG | RNPS1 | ENSG00000205937 | -0.7045807833242972 | [971] | [334,313] | -6 | hSpCas9 | negative selection | 1040155 | 2263082 | 2263105 | 16 | + | 26627737 | RPE1 | viability after 9 days | CGCAGGGCACTCACTTGGAGCGG | RNPS1 | ENSG00000205937 | 0.7599702279392011 | [1228] | [658,641] | 5 | hSpCas9 | negative selection | 1122470 | 2263082 | 2263105 | 16 | + | 26627737 | RPE1 | viability after 12 days | CGCAGGGCACTCACTTGGAGCGG | RNPS1 | ENSG00000205937 | 0.7062952376056773 | [1228] | [512,565] | 4 | hSpCas9 | negative selection | 1204785 | 2263082 | 2263105 | 16 | + | 26627737 | RPE1 | viability after 15 days | CGCAGGGCACTCACTTGGAGCGG | RNPS1 | ENSG00000205937 | 0.5400598693540619 | [1228] | [448,559] | 3 | hSpCas9 | negative selection | 1287100 | 2263082 | 2263105 | 16 | + | 26627737 | RPE1 | viability after 18 days | CGCAGGGCACTCACTTGGAGCGG | RNPS1 | ENSG00000205937 | 0.147115480855192 | [1228] | [316,420] | 1 | hSpCas9 | negative selection | 1369415 | 2263082 | 2263105 | 16 | + | 26627737 | HeLa | viability after 8 days | CGCAGGGCACTCACTTGGAGCGG | RNPS1 | ENSG00000205937 | -0.559365192320322 | [2235] | [811,598,606] | -5 | hSpCas9 | negative selection | 1451730 | 2263082 | 2263105 | 16 | + | 26627737 | HeLa | viability after 12 days | CGCAGGGCACTCACTTGGAGCGG | RNPS1 | ENSG00000205937 | -0.7692006902832789 | [2235] | [321,722,555] | -6 | hSpCas9 | negative selection | 1534045 | 2263082 | 2263105 | 16 | + | 26627737 | HeLa | viability after 15 days | CGCAGGGCACTCACTTGGAGCGG | RNPS1 | ENSG00000205937 | -0.6235714967607218 | [2235] | [395,751,629] | -5 | hSpCas9 | negative selection | 1616360 | 2263082 | 2263105 | 16 | + | 26627737 | HeLa | viability after 18 days | CGCAGGGCACTCACTTGGAGCGG | RNPS1 | ENSG00000205937 | -0.6443624340072593 | [2235] | [260,607,629] | -5 | hSpCas9 | negative selection | 1698675 | 2263082 | 2263105 | 16 | + | 26627737 | HCT116 | viability after 6 days | CGCAGGGCACTCACTTGGAGCGG | RNPS1 | ENSG00000205937 | 0.07701701170916664 | [3088] | [800,352] | 0 | hSpCas9 | negative selection | 1780990 | 2263082 | 2263105 | 16 | + | 26627737 | HCT116 | viability after 8 days | CGCAGGGCACTCACTTGGAGCGG | RNPS1 | ENSG00000205937 | 0.4221691462860202 | [792] | [503,742,508] | 4 | hSpCas9 | negative selection | 1863305 | 2263082 | 2263105 | 16 | + | 26627737 | HCT116 | viability after 9 days | CGCAGGGCACTCACTTGGAGCGG | RNPS1 | ENSG00000205937 | -0.03136453750494317 | [3088] | [853,769] | 0 | hSpCas9 | negative selection | 1945620 | 2263082 | 2263105 | 16 | + | 26627737 | HCT116 | viability after 12 days | CGCAGGGCACTCACTTGGAGCGG | RNPS1 | ENSG00000205937 | 0.37701075084763414 | [792] | [542,728,355] | 4 | hSpCas9 | negative selection | 2027935 | 2263082 | 2263105 | 16 | + | 26627737 | HCT116 | viability after 15 days | CGCAGGGCACTCACTTGGAGCGG | RNPS1 | ENSG00000205937 | 0.39703878995183506 | [792] | [604,783,412] | 4 | hSpCas9 | negative selection | 2110250 | 2263082 | 2263105 | 16 | + | 26627737 | HCT116 | viability after 18 days | CGCAGGGCACTCACTTGGAGCGG | RNPS1 | ENSG00000205937 | 0.3932050685981032 | [792] | [444,582,475] | 3 | hSpCas9 | negative selection | 2192565 | 2262419 | 2262442 | 16 | - | 24336569 | HL60 | viability | TTCCCTCTAGGATCACATCATGG | RNPS1 | ENSG00000205937 | 0.018071572922018275 | [671] | [1439] | 0 | hSpCas9 | negative selection | 2290115 | 2262733 | 2262756 | 16 | + | 24336569 | HL60 | viability | TCCTCACCTTTGTCACATTCCGG | RNPS1 | ENSG00000205937 | 0.7672634694214838 | [328] | [1184] | 6 | hSpCas9 | negative selection | 2290116 | 2263082 | 2263105 | 16 | + | 24336569 | HL60 | viability | CGCAGGGCACTCACTTGGAGCGG | RNPS1 | ENSG00000205937 | -0.2233708116666001 | [442] | [802] | -2 | hSpCas9 | negative selection | 2290117 | 2263194 | 2263217 | 16 | + | 24336569 | HL60 | viability | TCCTGAGCGGCTGGATGCTGAGG | RNPS1 | ENSG00000205937 | -0.692949158894037 | [795] | [1041] | -6 | hSpCas9 | negative selection | 2290118 | 2264172 | 2264195 | 16 | - | 24336569 | HL60 | viability | GTGGTAGCAGCAGTACCAGGTGG | RNPS1 | ENSG00000205937 | -0.21006875203444486 | [298] | [546] | -2 | hSpCas9 | negative selection | 2290119 | 2264195 | 2264218 | 16 | + | 24336569 | HL60 | viability | TGGAAGCGCTGCGCCTCTTTCGG | RNPS1 | ENSG00000205937 | -0.5785286236039127 | [584] | [828] | -5 | hSpCas9 | negative selection | 2290120 | 2264313 | 2264336 | 16 | + | 24336569 | HL60 | viability | TTTGGTAGGTGAAGGAGCCCTGG | RNPS1 | ENSG00000205937 | -0.14321511172034035 | [357] | [685] | -1 | hSpCas9 | negative selection | 2290121 | 2264560 | 2264583 | 16 | + | 24336569 | HL60 | viability | ACAGAAGGATTACCTAGTGCTGG | RNPS1 | ENSG00000205937 | 1.8729893059077976 | [180] | [1402] | 9 | hSpCas9 | negative selection | 2290122 | 2262419 | 2262442 | 16 | - | 24336569 | KBM7 | viability | TTCCCTCTAGGATCACATCATGG | RNPS1 | ENSG00000205937 | -1.3377015787765092 | [694] | [749] | -7 | hSpCas9 | negative selection | 2357292 | 2262733 | 2262756 | 16 | + | 24336569 | KBM7 | viability | TCCTCACCTTTGTCACATTCCGG | RNPS1 | ENSG00000205937 | 0.8426103532225894 | [431] | [2112] | 7 | hSpCas9 | negative selection | 2357293 | 2263082 | 2263105 | 16 | + | 24336569 | KBM7 | viability | CGCAGGGCACTCACTTGGAGCGG | RNPS1 | ENSG00000205937 | -0.6143576426743309 | [228] | [407] | -5 | hSpCas9 | negative selection | 2357294 | 2263194 | 2263217 | 16 | + | 24336569 | KBM7 | viability | TCCTGAGCGGCTGGATGCTGAGG | RNPS1 | ENSG00000205937 | -0.7373746704954358 | [554] | [907] | -5 | hSpCas9 | negative selection | 2357295 | 2264172 | 2264195 | 16 | - | 24336569 | KBM7 | viability | GTGGTAGCAGCAGTACCAGGTGG | RNPS1 | ENSG00000205937 | -0.9590012322520689 | [195] | [274] | -6 | hSpCas9 | negative selection | 2357296 | 2264195 | 2264218 | 16 | + | 24336569 | KBM7 | viability | TGGAAGCGCTGCGCCTCTTTCGG | RNPS1 | ENSG00000205937 | 1.1204790679344685 | [185] | [1102] | 8 | hSpCas9 | negative selection | 2357297 | 2264313 | 2264336 | 16 | + | 24336569 | KBM7 | viability | TTTGGTAGGTGAAGGAGCCCTGG | RNPS1 | ENSG00000205937 | 0.21937667636958136 | [227] | [723] | 2 | hSpCas9 | negative selection | 2357298 | 2264560 | 2264583 | 16 | + | 24336569 | KBM7 | viability | ACAGAAGGATTACCTAGTGCTGG | RNPS1 | ENSG00000205937 | 0.17408905614561507 | [400] | [1233] | 1 | hSpCas9 | negative selection | 2357299 | 2267448 | 2267471 | 16 | + | 25494202 | A375 | resistance to PLX-4720 (puromycin) | CCACCGTGCTCGGTCCATAGTGG | RNPS1 | ENSG00000205937 | -1.44334467068443 | [123,264] | [17,12] | -8 | dCas9-VP64 | positive selection | 2424422 | 2267493 | 2267516 | 16 | - | 25494202 | A375 | resistance to PLX-4720 (puromycin) | GGACTCCCGTGTGCAATTATCGG | RNPS1 | ENSG00000205937 | 0.7345160679926852 | [131,40] | [3,59] | 3 | dCas9-VP64 | positive selection | 2424423 | 2267514 | 2267537 | 16 | - | 25494202 | A375 | resistance to PLX-4720 (puromycin) | TGTACTCCGCGAACGTTTCCCGG | RNPS1 | ENSG00000205937 | -2.5326356998575372 | [7,93] | [1,0] | -9 | dCas9-VP64 | positive selection | 2424424 | 2267967 | 2267990 | 16 | + | 25494202 | A375 | resistance to PLX-4720 (puromycin) | AGGAGTGGACCGGCTTCACGAGG | RNPS1 | ENSG00000205937 | 2.1271339669689198 | [35,43] | [53,22] | 7 | dCas9-VP64 | positive selection | 2440490 | 2268041 | 2268064 | 16 | - | 25494202 | A375 | resistance to PLX-4720 (puromycin) | CGGGAAGATGTAAGTTGGGGCGG | RNPS1 | ENSG00000205937 | 0.039019200738175996 | [30,7] | [3,3] | 0 | dCas9-VP64 | positive selection | 2440491 | 2268006 | 2268029 | 16 | - | 25494202 | A375 | resistance to PLX-4720 (puromycin) | TCCGTGTTTCGGGGGCTGCCCGG | RNPS1 | ENSG00000205937 | -1.0397957559031075 | [2,30] | [0,1] | -6 | dCas9-VP64 | positive selection | 2440492 | 2267448 | 2267471 | 16 | + | 25494202 | A375 | resistance to PLX-4720 (zeocin) | CCACCGTGCTCGGTCCATAGTGG | RNPS1 | ENSG00000205937 | 0.8507460405026002 | [151,315] | [237,42] | 5 | dCas9-VP64 | positive selection | 2519677 | 2267493 | 2267516 | 16 | - | 25494202 | A375 | resistance to PLX-4720 (zeocin) | GGACTCCCGTGTGCAATTATCGG | RNPS1 | ENSG00000205937 | 0.3241240983538489 | [147,68] | [66,22] | 2 | dCas9-VP64 | positive selection | 2519678 | 2267514 | 2267537 | 16 | - | 25494202 | A375 | resistance to PLX-4720 (zeocin) | TGTACTCCGCGAACGTTTCCCGG | RNPS1 | ENSG00000205937 | 0.10603570158088077 | [103,66] | [32,26] | 0 | dCas9-VP64 | positive selection | 2519679 | 2267967 | 2267990 | 16 | + | 25494202 | A375 | resistance to PLX-4720 (zeocin) | AGGAGTGGACCGGCTTCACGAGG | RNPS1 | ENSG00000205937 | -0.48146471178251243 | [122,296] | [38,56] | -5 | dCas9-VP64 | positive selection | 2535745 | 2268041 | 2268064 | 16 | - | 25494202 | A375 | resistance to PLX-4720 (zeocin) | CGGGAAGATGTAAGTTGGGGCGG | RNPS1 | ENSG00000205937 | 0.20070199623758156 | [48,36] | [7,22] | 1 | dCas9-VP64 | positive selection | 2535746 | 2268006 | 2268029 | 16 | - | 25494202 | A375 | resistance to PLX-4720 (zeocin) | TCCGTGTTTCGGGGGCTGCCCGG | RNPS1 | ENSG00000205937 | 0.5881080278133628 | [10,30] | [3,15] | 4 | dCas9-VP64 | positive selection | 2535747 | 2264283 | 2264306 | 16 | + | 27453484 | HT29 | resistance to T3SS1-dependent cytotoxicity | CCTTGGACTTCTCATCTGAGCGG | RNPS1 | ENSG00000205937 | -0.6625780978115356 | [3,3] | [1,1] | -7 | hSpCas9 | positive selection | 3017432 | 2264230 | 2264253 | 16 | - | 27453484 | HT29 | resistance to T3SS1-dependent cytotoxicity | GAGTCGAGTGAGAAGGATCGCGG | RNPS1 | ENSG00000205937 | -0.6140065440360973 | [4,4] | [2,1] | -7 | hSpCas9 | positive selection | 3017433 | 2263162 | 2263185 | 16 | + | 27453484 | HT29 | resistance to T3SS1-dependent cytotoxicity | GCTAGAGCTGGAGCTGCGGGAGG | RNPS1 | ENSG00000205937 | 1.1236148938732207 | [1,1] | [3,3] | 9 | hSpCas9 | positive selection | 3017434 | 2264261 | 2264284 | 16 | - | 27453484 | HT29 | resistance to T3SS1-dependent cytotoxicity | GGATCGCTCAAAAGATAAAGGGG | RNPS1 | ENSG00000205937 | -0.2009420443317872 | [2,3] | [2,1] | -3 | hSpCas9 | positive selection | 3017435 | 2264283 | 2264306 | 16 | + | 27453484 | HT29 | resistance to T3SS2-dependent cytotoxicity | CCTTGGACTTCTCATCTGAGCGG | RNPS1 | ENSG00000205937 | -0.5331939471130452 | [3,3] | [1,0] | -7 | hSpCas9 | positive selection | 3085290 | 2264230 | 2264253 | 16 | - | 27453484 | HT29 | resistance to T3SS2-dependent cytotoxicity | GAGTCGAGTGAGAAGGATCGCGG | RNPS1 | ENSG00000205937 | 0.06555361159140491 | [4,4] | [2,3] | 1 | hSpCas9 | positive selection | 3085291 | 2263162 | 2263185 | 16 | + | 27453484 | HT29 | resistance to T3SS2-dependent cytotoxicity | GCTAGAGCTGGAGCTGCGGGAGG | RNPS1 | ENSG00000205937 | 0.058832375654544355 | [1,1] | [1,0] | 1 | hSpCas9 | positive selection | 3085292 | 2264261 | 2264284 | 16 | - | 27453484 | HT29 | resistance to T3SS2-dependent cytotoxicity | GGATCGCTCAAAAGATAAAGGGG | RNPS1 | ENSG00000205937 | 0.44527632699659164 | [2,2] | [2,2] | 7 | hSpCas9 | positive selection | 3085293 | 2264191 | 2264214 | | - | 24336571 | A375 | resistance to PLX after 7 days | AAGAGGCGCAGCGCTTCCAGTGG | RNPS1 | ENSG00000205937 | 0.15262562791233147 | [1,1] | [2,1] | 5 | hSpCas9 | positive selection | 3141491 | 2264207 | 2264230 | | + | 24336571 | A375 | resistance to PLX after 7 days | GCCTCTTTCGGGTTTTGTCCCGG | RNPS1 | ENSG00000205937 | 0.08396495348103872 | [4,4] | [4,5] | 3 | hSpCas9 | positive selection | 3141492 | 2263195 | 2263218 | | - | 24336571 | A375 | resistance to PLX after 7 days | TCCTCAGCATCCAGCCGCTCAGG | RNPS1 | ENSG00000205937 | -0.17146601171828135 | [8,9] | [7,7] | -5 | hSpCas9 | positive selection | 3141493 | 2264191 | 2264214 | | - | 24336571 | A375 | resistance to PLX after 14 days | AAGAGGCGCAGCGCTTCCAGTGG | RNPS1 | ENSG00000205937 | 0.6957076338001891 | [1,1] | [1,1] | 6 | hSpCas9 | positive selection | 3199284 | 2264207 | 2264230 | | + | 24336571 | A375 | resistance to PLX after 14 days | GCCTCTTTCGGGTTTTGTCCCGG | RNPS1 | ENSG00000205937 | -0.5299460929673807 | [4,7] | [1,1] | -6 | hSpCas9 | positive selection | 3199285 | 2263195 | 2263218 | | - | 24336571 | A375 | resistance to PLX after 14 days | TCCTCAGCATCCAGCCGCTCAGG | RNPS1 | ENSG00000205937 | -0.1601882489937646 | [6,5] | [1,2] | -2 | hSpCas9 | positive selection | 3199286 | 2264191 | 2264214 | | - | 24336571 | A375 | viability after 7 days | AAGAGGCGCAGCGCTTCCAGTGG | RNPS1 | ENSG00000205937 | -0.5339767663569885 | [3] | [1,1] | -6 | hSpCas9 | negative selection | 3257077 | 2264207 | 2264230 | | + | 24336571 | A375 | viability after 7 days | GCCTCTTTCGGGTTTTGTCCCGG | RNPS1 | ENSG00000205937 | -0.44100068382169544 | [7] | [4,4] | -6 | hSpCas9 | negative selection | 3257078 | 2263195 | 2263218 | | - | 24336571 | A375 | viability after 7 days | TCCTCAGCATCCAGCCGCTCAGG | RNPS1 | ENSG00000205937 | -0.18536424334267892 | [10] | [8,9] | -3 | hSpCas9 | negative selection | 3257079 | 2264191 | 2264214 | | - | 24336571 | A375 | viability after 14 days | AAGAGGCGCAGCGCTTCCAGTGG | RNPS1 | ENSG00000205937 | -0.6067278409188392 | [3] | [1,1] | -6 | hSpCas9 | negative selection | 3314870 | 2264207 | 2264230 | | + | 24336571 | A375 | viability after 14 days | GCCTCTTTCGGGTTTTGTCCCGG | RNPS1 | ENSG00000205937 | -0.09228505111880059 | [7] | [4,7] | -1 | hSpCas9 | negative selection | 3314871 | 2263195 | 2263218 | | - | 24336571 | A375 | viability after 14 days | TCCTCAGCATCCAGCCGCTCAGG | RNPS1 | ENSG00000205937 | -0.6152251059792857 | [10] | [6,5] | -6 | hSpCas9 | negative selection | 3314872 | 2263195 | 2263218 | 16 | - | 27383988 | 293T | resistance to West Nile virus (flavivirus) | TCCTCAGCATCCAGCCGCTCAGG | RNPS1 | ENSG00000205937 | -0.8141361511107891 | [268,268] | [0,0] | -5 | hSpCas9 | positive selection | 3390286 | 2262739 | 2262762 | 16 | - | 27383988 | 293T | resistance to West Nile virus (flavivirus) | ACTCACCCGGAATGTGACAAAGG | RNPS1 | ENSG00000205937 | 3.087401210003523 | [17,17] | [0,0] | 8 | hSpCas9 | positive selection | 3390287 | 2264191 | 2264214 | 16 | - | 27383988 | 293T | resistance to West Nile virus (flavivirus) | AAGAGGCGCAGCGCTTCCAGTGG | RNPS1 | ENSG00000205937 | 5.257326211445835 | [3,3] | [0,0] | 9 | hSpCas9 | positive selection | 3390288 | 2264282 | 2264305 | 16 | + | 26780180 | HT29 | viability (Avana library 4 designs) | CCTTGGACTTCTCATCTGAGCGG | RNPS1 | ENSG00000205937 | 3.81215297184355 | [] | [] | 9 | hSpCas9 | negative selection | 3455815 | 2264230 | 2264253 | 16 | - | 26780180 | HT29 | viability (Avana library 4 designs) | GAGTCGAGTGAGAAGGATCGCGG | RNPS1 | ENSG00000205937 | 3.15228004763443 | [] | [] | 8 | hSpCas9 | negative selection | 3455816 | 2263161 | 2263184 | 16 | + | 26780180 | HT29 | viability (Avana library 4 designs) | GCTAGAGCTGGAGCTGCGGGAGG | RNPS1 | ENSG00000205937 | 2.05393383166906 | [] | [] | 7 | hSpCas9 | negative selection | 3455817 | 2264261 | 2264284 | 16 | - | 26780180 | HT29 | viability (Avana library 4 designs) | GGATCGCTCAAAAGATAAAGGGG | RNPS1 | ENSG00000205937 | 2.22334808819854 | [] | [] | 7 | hSpCas9 | negative selection | 3455818 | 2264282 | 2264305 | 16 | + | 26780180 | A375 | viability (Avana lentiCRISPRv2) | CCTTGGACTTCTCATCTGAGCGG | RNPS1 | ENSG00000205937 | -8.34012896825288 | [] | [] | -7 | hSpCas9 | negative selection | 3553980 | 2264261 | 2264284 | 16 | - | 26780180 | A375 | viability (Avana lentiCRISPRv2) | GGATCGCTCAAAAGATAAAGGGG | RNPS1 | ENSG00000205937 | -10.3789550571812 | [] | [] | -8 | hSpCas9 | negative selection | 3553981 | 2263161 | 2263184 | 16 | + | 26780180 | A375 | viability (Avana lentiCRISPRv2) | GCTAGAGCTGGAGCTGCGGGAGG | RNPS1 | ENSG00000205937 | -6.73691887112705 | [] | [] | -6 | hSpCas9 | negative selection | 3553982 | 2264230 | 2264253 | 16 | - | 26780180 | A375 | viability (Avana lentiCRISPRv2) | GAGTCGAGTGAGAAGGATCGCGG | RNPS1 | ENSG00000205937 | -4.9530622157313 | [] | [] | -5 | hSpCas9 | negative selection | 3553983 | 2262765 | 2262788 | 16 | - | 26780180 | A375 | viability (Avana lentiCRISPRv2) | AAGCCCACCAAAGTGCACATTGG | RNPS1 | ENSG00000205937 | -6.67777492772328 | [] | [] | -6 | hSpCas9 | negative selection | 3553984 | 2264262 | 2264285 | 16 | - | 26780180 | A375 | viability (Avana lentiCRISPRv2) | AGGATCGCTCAAAAGATAAAGGG | RNPS1 | ENSG00000205937 | -7.10463273427417 | [] | [] | -6 | hSpCas9 | negative selection | 3553985 | 2264282 | 2264305 | 16 | + | 26780180 | A375 | viability (Avana lentiGuide) | CCTTGGACTTCTCATCTGAGCGG | RNPS1 | ENSG00000205937 | 22.5895897091761 | [] | [] | 9 | hSpCas9 | negative selection | 3662639 | 2264261 | 2264284 | 16 | - | 26780180 | A375 | viability (Avana lentiGuide) | GGATCGCTCAAAAGATAAAGGGG | RNPS1 | ENSG00000205937 | 13.2859937582549 | [] | [] | 7 | hSpCas9 | negative selection | 3662640 | 2263161 | 2263184 | 16 | + | 26780180 | A375 | viability (Avana lentiGuide) | GCTAGAGCTGGAGCTGCGGGAGG | RNPS1 | ENSG00000205937 | 16.7741891692481 | [] | [] | 8 | hSpCas9 | negative selection | 3662641 | 2264230 | 2264253 | 16 | - | 26780180 | A375 | viability (Avana lentiGuide) | GAGTCGAGTGAGAAGGATCGCGG | RNPS1 | ENSG00000205937 | 17.0630680431853 | [] | [] | 8 | hSpCas9 | negative selection | 3662642 | 2262765 | 2262788 | 16 | - | 26780180 | A375 | viability (Avana lentiGuide) | AAGCCCACCAAAGTGCACATTGG | RNPS1 | ENSG00000205937 | 16.7710407243742 | [] | [] | 8 | hSpCas9 | negative selection | 3662643 | 2264262 | 2264285 | 16 | - | 26780180 | A375 | viability (Avana lentiGuide) | AGGATCGCTCAAAAGATAAAGGG | RNPS1 | ENSG00000205937 | 3.98485532641562 | [] | [] | 4 | hSpCas9 | negative selection | 3662644 | 2264282 | 2264305 | 16 | + | 26780180 | A375 | resistance to vemurafenib (Avana lentiCRISPRv2) | CCTTGGACTTCTCATCTGAGCGG | RNPS1 | ENSG00000205937 | -0.7809808970495449 | [5] | [2,2] | -8 | hSpCas9 | positive selection | 3771246 | 2264261 | 2264284 | 16 | - | 26780180 | A375 | resistance to vemurafenib (Avana lentiCRISPRv2) | GGATCGCTCAAAAGATAAAGGGG | RNPS1 | ENSG00000205937 | -1.7648639647544986 | [5] | [0,1] | -9 | hSpCas9 | positive selection | 3771247 | 2263161 | 2263184 | 16 | + | 26780180 | A375 | resistance to vemurafenib (Avana lentiCRISPRv2) | GCTAGAGCTGGAGCTGCGGGAGG | RNPS1 | ENSG00000205937 | -0.2494514218238459 | [3] | [2,2] | -4 | hSpCas9 | positive selection | 3771248 | 2264230 | 2264253 | 16 | - | 26780180 | A375 | resistance to vemurafenib (Avana lentiCRISPRv2) | GAGTCGAGTGAGAAGGATCGCGG | RNPS1 | ENSG00000205937 | -0.23480004898455403 | [6] | [4,4] | -4 | hSpCas9 | positive selection | 3771249 | 2262765 | 2262788 | 16 | - | 26780180 | A375 | resistance to vemurafenib (Avana lentiCRISPRv2) | AAGCCCACCAAAGTGCACATTGG | RNPS1 | ENSG00000205937 | -0.2553556185649726 | [4] | [3,4] | -4 | hSpCas9 | positive selection | 3771250 | 2264262 | 2264285 | 16 | - | 26780180 | A375 | resistance to vemurafenib (Avana lentiCRISPRv2) | AGGATCGCTCAAAAGATAAAGGG | RNPS1 | ENSG00000205937 | -0.9381565212837971 | [6] | [3,2] | -8 | hSpCas9 | positive selection | 3771251 | 2264282 | 2264305 | 16 | + | 26780180 | A375 | resistance to vemurafenib (Avana lentiGuide) | CCTTGGACTTCTCATCTGAGCGG | RNPS1 | ENSG00000205937 | -0.49407586561232736 | [5] | [2,3] | -6 | hSpCas9 | positive selection | 3879853 | 2264261 | 2264284 | 16 | - | 26780180 | A375 | resistance to vemurafenib (Avana lentiGuide) | GGATCGCTCAAAAGATAAAGGGG | RNPS1 | ENSG00000205937 | -1.0673174516125217 | [4] | [1,1] | -8 | hSpCas9 | positive selection | 3879854 | 2263161 | 2263184 | 16 | + | 26780180 | A375 | resistance to vemurafenib (Avana lentiGuide) | GCTAGAGCTGGAGCTGCGGGAGG | RNPS1 | ENSG00000205937 | -1.1545850020040604 | [3] | [0,0] | -8 | hSpCas9 | positive selection | 3879855 | 2264230 | 2264253 | 16 | - | 26780180 | A375 | resistance to vemurafenib (Avana lentiGuide) | GAGTCGAGTGAGAAGGATCGCGG | RNPS1 | ENSG00000205937 | -0.5221290902841984 | [6] | [2,4] | -6 | hSpCas9 | positive selection | 3879856 | 2262765 | 2262788 | 16 | - | 26780180 | A375 | resistance to vemurafenib (Avana lentiGuide) | AAGCCCACCAAAGTGCACATTGG | RNPS1 | ENSG00000205937 | -1.8822286340726313 | [5] | [0,0] | -9 | hSpCas9 | positive selection | 3879857 | 2264262 | 2264285 | 16 | - | 26780180 | A375 | resistance to vemurafenib (Avana lentiGuide) | AGGATCGCTCAAAAGATAAAGGG | RNPS1 | ENSG00000205937 | 0.0868811386747216 | [4] | [4,4] | 2 | hSpCas9 | positive selection | 3879858 | 2264191 | 2264214 | 16 | - | 26780180 | A375 | viability | AAGAGGCGCAGCGCTTCCAGTGG | RNPS1 | ENSG00000205937 | 0.621472979995995 | [] | [] | 2 | hSpCas9 | negative selection | 3989976 | 2262739 | 2262762 | 16 | - | 26780180 | A375 | viability | ACTCACCCGGAATGTGACAAAGG | RNPS1 | ENSG00000205937 | 2.29889473053655 | [] | [] | 9 | hSpCas9 | negative selection | 3989977 | 2262733 | 2262756 | 16 | + | 26780180 | A375 | viability | TCCTCACCTTTGTCACATTCCGG | RNPS1 | ENSG00000205937 | 1.13482510659695 | [] | [] | 6 | hSpCas9 | negative selection | 3989978 | 2263195 | 2263218 | 16 | - | 26780180 | A375 | viability | TCCTCAGCATCCAGCCGCTCAGG | RNPS1 | ENSG00000205937 | 1.78816264735001 | [] | [] | 9 | hSpCas9 | negative selection | 3989979 | 2262419 | 2262442 | 16 | - | 26780180 | A375 | viability | TTCCCTCTAGGATCACATCATGG | RNPS1 | ENSG00000205937 | 2.10821517616188 | [] | [] | 9 | hSpCas9 | negative selection | 3989980 | 2264191 | 2264214 | 16 | - | 26780180 | HT29 | viability (GeCKOv2 library) | AAGAGGCGCAGCGCTTCCAGTGG | RNPS1 | ENSG00000205937 | 0.830350789862568 | [] | [] | 3 | hSpCas9 | negative selection | 4097942 | 2262739 | 2262762 | 16 | - | 26780180 | HT29 | viability (GeCKOv2 library) | ACTCACCCGGAATGTGACAAAGG | RNPS1 | ENSG00000205937 | 3.10982278334113 | [] | [] | 9 | hSpCas9 | negative selection | 4097943 | 2262733 | 2262756 | 16 | + | 26780180 | HT29 | viability (GeCKOv2 library) | TCCTCACCTTTGTCACATTCCGG | RNPS1 | ENSG00000205937 | 0.015663694862061 | [] | [] | 0 | hSpCas9 | negative selection | 4097944 | 2263195 | 2263218 | 16 | - | 26780180 | HT29 | viability (GeCKOv2 library) | TCCTCAGCATCCAGCCGCTCAGG | RNPS1 | ENSG00000205937 | 1.0872048696215 | [] | [] | 5 | hSpCas9 | negative selection | 4097945 | 2262419 | 2262442 | 16 | - | 26780180 | HT29 | viability (GeCKOv2 library) | TTCCCTCTAGGATCACATCATGG | RNPS1 | ENSG00000205937 | 2.28935948796462 | [] | [] | 9 | hSpCas9 | negative selection | 4097946 | 2264191 | 2264214 | 16 | - | 26780180 | A375 | resistance to vemurafenib (GeCKOv1 lentiCRISPRv1) | AAGAGGCGCAGCGCTTCCAGTGG | RNPS1 | ENSG00000205937 | -0.5527877884358937 | [1] | [0,0] | -9 | hSpCas9 | positive selection | 4167032 | 2264207 | 2264230 | 16 | + | 26780180 | A375 | resistance to vemurafenib (GeCKOv1 lentiCRISPRv1) | GCCTCTTTCGGGTTTTGTCCCGG | RNPS1 | ENSG00000205937 | -0.807212976800838 | [3] | [0,0] | -9 | hSpCas9 | positive selection | 4167033 | 2263195 | 2263218 | 16 | - | 26780180 | A375 | resistance to vemurafenib (GeCKOv1 lentiCRISPRv1) | TCCTCAGCATCCAGCCGCTCAGG | RNPS1 | ENSG00000205937 | -0.3874975692128038 | [3] | [1,0] | -7 | hSpCas9 | positive selection | 4167034 | 2264191 | 2264214 | 16 | - | 26780180 | A375 | resistance to vemurafenib (GeCKOv1 lentiGuide) | AAGAGGCGCAGCGCTTCCAGTGG | RNPS1 | ENSG00000205937 | -0.29867432596828336 | [1] | [0,0,0,0] | -4 | hSpCas9 | positive selection | 4231054 | 2264207 | 2264230 | 16 | + | 26780180 | A375 | resistance to vemurafenib (GeCKOv1 lentiGuide) | GCCTCTTTCGGGTTTTGTCCCGG | RNPS1 | ENSG00000205937 | 0.5846912558850115 | [0] | [0,0,0,0] | 4 | hSpCas9 | positive selection | 4231055 | 2263195 | 2263218 | 16 | - | 26780180 | A375 | resistance to vemurafenib (GeCKOv1 lentiGuide) | TCCTCAGCATCCAGCCGCTCAGG | RNPS1 | ENSG00000205937 | -0.08224773752628983 | [3] | [3,0,0,0] | -1 | hSpCas9 | positive selection | 4231056 | 2262419 | 2262442 | 16 | - | 26780180 | A375 | resistance to vemurafenib (GeCKOv2 lentiGuide) | TTCCCTCTAGGATCACATCATGG | RNPS1 | ENSG00000205937 | -1.2119089940286414 | [3] | [1,0] | -9 | hSpCas9 | positive selection | 4295361 | 2262733 | 2262756 | 16 | + | 26780180 | A375 | resistance to vemurafenib (GeCKOv2 lentiGuide) | TCCTCACCTTTGTCACATTCCGG | RNPS1 | ENSG00000205937 | 0.28748154029241046 | [4] | [4,4] | 6 | hSpCas9 | positive selection | 4295363 | 2263195 | 2263218 | 16 | - | 26780180 | A375 | resistance to vemurafenib (GeCKOv2 lentiGuide) | TCCTCAGCATCCAGCCGCTCAGG | RNPS1 | ENSG00000205937 | -0.0634940418925532 | [4] | [2,2] | -1 | hSpCas9 | positive selection | 4359615 | 2262739 | 2262762 | 16 | - | 26780180 | A375 | resistance to vemurafenib (GeCKOv2 lentiGuide) | ACTCACCCGGAATGTGACAAAGG | RNPS1 | ENSG00000205937 | -0.7422007409119178 | [3] | [2,0] | -9 | hSpCas9 | positive selection | 4359616 | 2264191 | 2264214 | 16 | - | 26780180 | A375 | resistance to vemurafenib (GeCKOv2 lentiGuide) | AAGAGGCGCAGCGCTTCCAGTGG | RNPS1 | ENSG00000205937 | -0.3862706733204673 | [0] | [0,0] | -7 | hSpCas9 | positive selection | 4359617 | 2262400 | 2262422 | 16 | - | 27760321 | OCIAML3 | viability | TGGAGATATTTTCCACCTATGG | RNPS1 | ENSG00000205937 | -1.6849059661168477 | [123,97] | [28,23] | -8 | hSpCas9 | negative selection | 4435413 | 2262814 | 2262836 | 16 | + | 27760321 | OCIAML3 | viability | CCTTTTCATCTCTTTTAGGTGG | RNPS1 | ENSG00000205937 | 0.021730034555314415 | [235,224] | [230,120] | 0 | hSpCas9 | negative selection | 4435414 | 2263118 | 2263140 | 16 | + | 27760321 | OCIAML3 | viability | TGTCGTGTCTGCGCCGAGAAGG | RNPS1 | ENSG00000205937 | -1.8901927457116907 | [716,619] | [121,164] | -9 | hSpCas9 | negative selection | 4435415 | 2264208 | 2264230 | 16 | - | 27760321 | OCIAML3 | viability | CCGGGACAAAACCCGAAAGAGG | RNPS1 | ENSG00000205937 | -2.5136476496298896 | [122,86] | [18,7] | -9 | hSpCas9 | negative selection | 4435416 | 2264225 | 2264247 | 16 | - | 27760321 | OCIAML3 | viability | AGTGAGAAGGATCGCGGCCGGG | RNPS1 | ENSG00000205937 | -0.7654196990261849 | [471,405] | [203,197] | -6 | hSpCas9 | negative selection | 4435417 | 2262400 | 2262422 | 16 | - | 27760321 | OCIAML2 | viability | TGGAGATATTTTCCACCTATGG | RNPS1 | ENSG00000205937 | -0.19553383162024462 | [123,97] | [89,61] | -2 | hSpCas9 | negative selection | 4518876 | 2262814 | 2262836 | 16 | + | 27760321 | OCIAML2 | viability | CCTTTTCATCTCTTTTAGGTGG | RNPS1 | ENSG00000205937 | 0.24525359627344978 | [235,224] | [175,280] | 3 | hSpCas9 | negative selection | 4518877 | 2263118 | 2263140 | 16 | + | 27760321 | OCIAML2 | viability | TGTCGTGTCTGCGCCGAGAAGG | RNPS1 | ENSG00000205937 | -1.0891217025607718 | [716,619] | [281,215] | -8 | hSpCas9 | negative selection | 4518878 | 2264208 | 2264230 | 16 | - | 27760321 | OCIAML2 | viability | CCGGGACAAAACCCGAAAGAGG | RNPS1 | ENSG00000205937 | -1.96050384152861 | [122,86] | [18,24] | -9 | hSpCas9 | negative selection | 4518879 | 2264225 | 2264247 | 16 | - | 27760321 | OCIAML2 | viability | AGTGAGAAGGATCGCGGCCGGG | RNPS1 | ENSG00000205937 | -0.639816832129319 | [471,405] | [250,195] | -6 | hSpCas9 | negative selection | 4518880 | 2262400 | 2262422 | 16 | - | 27760321 | MV411 | viability | TGGAGATATTTTCCACCTATGG | RNPS1 | ENSG00000205937 | -0.020844500976323177 | [123,97] | [0,177] | 0 | hSpCas9 | negative selection | 4602339 | 2262814 | 2262836 | 16 | + | 27760321 | MV411 | viability | CCTTTTCATCTCTTTTAGGTGG | RNPS1 | ENSG00000205937 | 0.45310006474516673 | [235,224] | [96,375] | 3 | hSpCas9 | negative selection | 4602340 | 2263118 | 2263140 | 16 | + | 27760321 | MV411 | viability | TGTCGTGTCTGCGCCGAGAAGG | RNPS1 | ENSG00000205937 | -3.0812664239012433 | [716,619] | [31,81] | -9 | hSpCas9 | negative selection | 4602341 | 2264208 | 2264230 | 16 | - | 27760321 | MV411 | viability | CCGGGACAAAACCCGAAAGAGG | RNPS1 | ENSG00000205937 | -1.322395506709448 | [122,86] | [36,12] | -7 | hSpCas9 | negative selection | 4602342 | 2264225 | 2264247 | 16 | - | 27760321 | MV411 | viability | AGTGAGAAGGATCGCGGCCGGG | RNPS1 | ENSG00000205937 | 0.4547477778645761 | [471,405] | [510,222] | 3 | hSpCas9 | negative selection | 4602343 | 2262400 | 2262422 | 16 | - | 27760321 | HL60 | viability | TGGAGATATTTTCCACCTATGG | RNPS1 | ENSG00000205937 | 0.40071166026092175 | [123,97] | [83,155] | 5 | hSpCas9 | negative selection | 4685802 | 2262814 | 2262836 | 16 | + | 27760321 | HL60 | viability | CCTTTTCATCTCTTTTAGGTGG | RNPS1 | ENSG00000205937 | 1.960581950357059 | [235,224] | [893,563] | 9 | hSpCas9 | negative selection | 4685803 | 2263118 | 2263140 | 16 | + | 27760321 | HL60 | viability | TGTCGTGTCTGCGCCGAGAAGG | RNPS1 | ENSG00000205937 | -1.637318744722079 | [716,619] | [193,154] | -8 | hSpCas9 | negative selection | 4685804 | 2264208 | 2264230 | 16 | - | 27760321 | HL60 | viability | CCGGGACAAAACCCGAAAGAGG | RNPS1 | ENSG00000205937 | -2.321813595867155 | [122,86] | [15,17] | -9 | hSpCas9 | negative selection | 4685805 | 2264225 | 2264247 | 16 | - | 27760321 | HL60 | viability | AGTGAGAAGGATCGCGGCCGGG | RNPS1 | ENSG00000205937 | 0.06067453962466772 | [471,405] | [320,427] | 0 | hSpCas9 | negative selection | 4685806 | 2262400 | 2262422 | 16 | - | 27760321 | HT1080 | viability | TGGAGATATTTTCCACCTATGG | RNPS1 | ENSG00000205937 | -5.123992925797117 | [97,76] | [0,0] | -8 | hSpCas9 | negative selection | 4769265 | 2262814 | 2262836 | 16 | + | 27760321 | HT1080 | viability | CCTTTTCATCTCTTTTAGGTGG | RNPS1 | ENSG00000205937 | -0.8134293912140361 | [224,175] | [33,57] | -3 | hSpCas9 | negative selection | 4769266 | 2263118 | 2263140 | 16 | + | 27760321 | HT1080 | viability | TGTCGTGTCTGCGCCGAGAAGG | RNPS1 | ENSG00000205937 | -3.2301020436490933 | [619,483] | [0,47] | -7 | hSpCas9 | negative selection | 4769267 | 2264208 | 2264230 | 16 | - | 27760321 | HT1080 | viability | CCGGGACAAAACCCGAAAGAGG | RNPS1 | ENSG00000205937 | -2.5751563346446273 | [86,67] | [8,0] | -7 | hSpCas9 | negative selection | 4769268 | 2264225 | 2264247 | 16 | - | 27760321 | HT1080 | viability | AGTGAGAAGGATCGCGGCCGGG | RNPS1 | ENSG00000205937 | -5.887895619196346 | [405,316] | [0,3] | -8 | hSpCas9 | negative selection | 4769269 | 2262400 | 2262422 | 16 | - | 27760321 | HT29 | viability after 7 days | TGGAGATATTTTCCACCTATGG | RNPS1 | ENSG00000205937 | -1.1493603976137048 | [97,76] | [59,27,64] | -8 | hSpCas9 | negative selection | 4852728 | 2262814 | 2262836 | 16 | + | 27760321 | HT29 | viability after 7 days | CCTTTTCATCTCTTTTAGGTGG | RNPS1 | ENSG00000205937 | -0.5206716459117485 | [224,175] | [144,274,115] | -6 | hSpCas9 | negative selection | 4852729 | 2263118 | 2263140 | 16 | + | 27760321 | HT29 | viability after 7 days | TGTCGTGTCTGCGCCGAGAAGG | RNPS1 | ENSG00000205937 | -0.9696678276508617 | [619,483] | [572,285,260] | -8 | hSpCas9 | negative selection | 4852730 | 2264208 | 2264230 | 16 | - | 27760321 | HT29 | viability after 7 days | CCGGGACAAAACCCGAAAGAGG | RNPS1 | ENSG00000205937 | -1.207685418406141 | [86,67] | [68,18,44] | -9 | hSpCas9 | negative selection | 4852731 | 2264225 | 2264247 | 16 | - | 27760321 | HT29 | viability after 7 days | AGTGAGAAGGATCGCGGCCGGG | RNPS1 | ENSG00000205937 | 0.10523151179923744 | [405,316] | [528,368,601] | 1 | hSpCas9 | negative selection | 4852732 | 2262400 | 2262422 | 16 | - | 27760321 | HT29 | viability after 25 days | TGGAGATATTTTCCACCTATGG | RNPS1 | ENSG00000205937 | -6.64367519064364 | [97,76] | [0,0,0] | -9 | hSpCas9 | negative selection | 4936191 | 2262814 | 2262836 | 16 | + | 27760321 | HT29 | viability after 25 days | CCTTTTCATCTCTTTTAGGTGG | RNPS1 | ENSG00000205937 | 0.6432602788807997 | [224,175] | [448,307,304] | 7 | hSpCas9 | negative selection | 4936192 | 2263118 | 2263140 | 16 | + | 27760321 | HT29 | viability after 25 days | TGTCGTGTCTGCGCCGAGAAGG | RNPS1 | ENSG00000205937 | -1.957098261615971 | [619,483] | [67,211,218] | -8 | hSpCas9 | negative selection | 4936193 | 2264208 | 2264230 | 16 | - | 27760321 | HT29 | viability after 25 days | CCGGGACAAAACCCGAAAGAGG | RNPS1 | ENSG00000205937 | 0.4413985934682607 | [86,67] | [112,102,147] | 5 | hSpCas9 | negative selection | 4936194 | 2264225 | 2264247 | 16 | - | 27760321 | HT29 | viability after 25 days | AGTGAGAAGGATCGCGGCCGGG | RNPS1 | ENSG00000205937 | -0.543967588814923 | [405,316] | [204,336,315] | -5 | hSpCas9 | negative selection | 4936195 | 2262400 | 2262422 | 16 | - | 27760321 | HT29 | viability after 22 days | TGGAGATATTTTCCACCTATGG | RNPS1 | ENSG00000205937 | -3.2141882215414386 | [97,76] | [0,18,12] | -8 | hSpCas9 | negative selection | 5019654 | 2262814 | 2262836 | 16 | + | 27760321 | HT29 | viability after 22 days | CCTTTTCATCTCTTTTAGGTGG | RNPS1 | ENSG00000205937 | -0.07877814186995935 | [224,175] | [177,221,259] | -1 | hSpCas9 | negative selection | 5019655 | 2263118 | 2263140 | 16 | + | 27760321 | HT29 | viability after 22 days | TGTCGTGTCTGCGCCGAGAAGG | RNPS1 | ENSG00000205937 | -2.4089423048060943 | [619,483] | [114,84,160] | -8 | hSpCas9 | negative selection | 5019656 | 2264208 | 2264230 | 16 | - | 27760321 | HT29 | viability after 22 days | CCGGGACAAAACCCGAAAGAGG | RNPS1 | ENSG00000205937 | 0.05943189817157046 | [86,67] | [62,116,100] | 0 | hSpCas9 | negative selection | 5019657 | 2264225 | 2264247 | 16 | - | 27760321 | HT29 | viability after 22 days | AGTGAGAAGGATCGCGGCCGGG | RNPS1 | ENSG00000205937 | 0.0474039508021048 | [405,316] | [506,312,473] | 0 | hSpCas9 | negative selection | 5019658 | 2262400 | 2262422 | 16 | - | 27760321 | HT29 | viability after 19 days | TGGAGATATTTTCCACCTATGG | RNPS1 | ENSG00000205937 | -5.6010418795113655 | [97,76] | [0,0,3] | -9 | hSpCas9 | negative selection | 5103117 | 2262814 | 2262836 | 16 | + | 27760321 | HT29 | viability after 19 days | CCTTTTCATCTCTTTTAGGTGG | RNPS1 | ENSG00000205937 | 1.4844479843515384 | [224,175] | [706,219,990] | 9 | hSpCas9 | negative selection | 5103118 | 2263118 | 2263140 | 16 | + | 27760321 | HT29 | viability after 19 days | TGTCGTGTCTGCGCCGAGAAGG | RNPS1 | ENSG00000205937 | -0.734533525019042 | [619,483] | [89,162,836] | -5 | hSpCas9 | negative selection | 5103119 | 2264208 | 2264230 | 16 | - | 27760321 | HT29 | viability after 19 days | CCGGGACAAAACCCGAAAGAGG | RNPS1 | ENSG00000205937 | -0.9200903818726642 | [86,67] | [55,52,32] | -6 | hSpCas9 | negative selection | 5103120 | 2264225 | 2264247 | 16 | - | 27760321 | HT29 | viability after 19 days | AGTGAGAAGGATCGCGGCCGGG | RNPS1 | ENSG00000205937 | -0.4472063863318496 | [405,316] | [368,339,210] | -4 | hSpCas9 | negative selection | 5103121 | 2262400 | 2262422 | 16 | - | 27760321 | HT29 | viability after 16 days | TGGAGATATTTTCCACCTATGG | RNPS1 | ENSG00000205937 | -1.2322198588573094 | [97,76] | [4,25,90] | -7 | hSpCas9 | negative selection | 5186580 | 2262814 | 2262836 | 16 | + | 27760321 | HT29 | viability after 16 days | CCTTTTCATCTCTTTTAGGTGG | RNPS1 | ENSG00000205937 | 0.15040628035624803 | [224,175] | [358,147,252] | 1 | hSpCas9 | negative selection | 5186581 | 2263118 | 2263140 | 16 | + | 27760321 | HT29 | viability after 16 days | TGTCGTGTCTGCGCCGAGAAGG | RNPS1 | ENSG00000205937 | -1.1788591031727949 | [619,483] | [267,152,399] | -7 | hSpCas9 | negative selection | 5186582 | 2264208 | 2264230 | 16 | - | 27760321 | HT29 | viability after 16 days | CCGGGACAAAACCCGAAAGAGG | RNPS1 | ENSG00000205937 | 0.08667106079223563 | [86,67] | [52,112,105] | 0 | hSpCas9 | negative selection | 5186583 | 2264225 | 2264247 | 16 | - | 27760321 | HT29 | viability after 16 days | AGTGAGAAGGATCGCGGCCGGG | RNPS1 | ENSG00000205937 | -0.13278062784977676 | [405,316] | [596,298,233] | -1 | hSpCas9 | negative selection | 5186584 | 2262400 | 2262422 | 16 | - | 27760321 | HT29 | viability after 13 days | TGGAGATATTTTCCACCTATGG | RNPS1 | ENSG00000205937 | -3.333345982935932 | [97,76] | [0,14,13] | -9 | hSpCas9 | negative selection | 5270043 | 2262814 | 2262836 | 16 | + | 27760321 | HT29 | viability after 13 days | CCTTTTCATCTCTTTTAGGTGG | RNPS1 | ENSG00000205937 | 0.269375373262264 | [224,175] | [387,259,197] | 3 | hSpCas9 | negative selection | 5270044 | 2263118 | 2263140 | 16 | + | 27760321 | HT29 | viability after 13 days | TGTCGTGTCTGCGCCGAGAAGG | RNPS1 | ENSG00000205937 | -2.1414859751320234 | [619,483] | [131,150,151] | -8 | hSpCas9 | negative selection | 5270045 | 2264208 | 2264230 | 16 | - | 27760321 | HT29 | viability after 13 days | CCGGGACAAAACCCGAAAGAGG | RNPS1 | ENSG00000205937 | -0.2340150552511302 | [86,67] | [47,114,66] | -3 | hSpCas9 | negative selection | 5270046 | 2264225 | 2264247 | 16 | - | 27760321 | HT29 | viability after 13 days | AGTGAGAAGGATCGCGGCCGGG | RNPS1 | ENSG00000205937 | -0.2801653820977832 | [405,316] | [313,391,330] | -3 | hSpCas9 | negative selection | 5270047 | 2262400 | 2262422 | 16 | - | 27760321 | HT29 | viability after 10 days | TGGAGATATTTTCCACCTATGG | RNPS1 | ENSG00000205937 | -1.2520314434137285 | [97,76] | [69,41,25] | -8 | hSpCas9 | negative selection | 5353506 | 2262814 | 2262836 | 16 | + | 27760321 | HT29 | viability after 10 days | CCTTTTCATCTCTTTTAGGTGG | RNPS1 | ENSG00000205937 | 0.1905805532459477 | [224,175] | [401,250,204] | 2 | hSpCas9 | negative selection | 5353507 | 2263118 | 2263140 | 16 | + | 27760321 | HT29 | viability after 10 days | TGTCGTGTCTGCGCCGAGAAGG | RNPS1 | ENSG00000205937 | -0.8304386273290673 | [619,483] | [317,444,400] | -7 | hSpCas9 | negative selection | 5353508 | 2264208 | 2264230 | 16 | - | 27760321 | HT29 | viability after 10 days | CCGGGACAAAACCCGAAAGAGG | RNPS1 | ENSG00000205937 | -0.1032339854461588 | [86,67] | [60,77,129] | -1 | hSpCas9 | negative selection | 5353509 | 2264225 | 2264247 | 16 | - | 27760321 | HT29 | viability after 10 days | AGTGAGAAGGATCGCGGCCGGG | RNPS1 | ENSG00000205937 | -0.18986060447482403 | [405,316] | [257,355,567] | -2 | hSpCas9 | negative selection | 5353510 | 2262400 | 2262422 | 16 | - | 27760321 | MOLM13 | viability | TGGAGATATTTTCCACCTATGG | RNPS1 | ENSG00000205937 | 1.1892684007086465 | [123,97] | [122,157] | 8 | hSpCas9 | negative selection | 5436969 | 2262814 | 2262836 | 16 | + | 27760321 | MOLM13 | viability | CCTTTTCATCTCTTTTAGGTGG | RNPS1 | ENSG00000205937 | 0.6261668793657279 | [235,224] | [106,280] | 4 | hSpCas9 | negative selection | 5436970 | 2263118 | 2263140 | 16 | + | 27760321 | MOLM13 | viability | TGTCGTGTCTGCGCCGAGAAGG | RNPS1 | ENSG00000205937 | -3.7220958575400926 | [716,619] | [14,39] | -9 | hSpCas9 | negative selection | 5436971 | 2264208 | 2264230 | 16 | - | 27760321 | MOLM13 | viability | CCGGGACAAAACCCGAAAGAGG | RNPS1 | ENSG00000205937 | -3.077558794073697 | [122,86] | [0,11] | -9 | hSpCas9 | negative selection | 5436972 | 2264225 | 2264247 | 16 | - | 27760321 | MOLM13 | viability | AGTGAGAAGGATCGCGGCCGGG | RNPS1 | ENSG00000205937 | -2.2518042858552043 | [471,405] | [73,32] | -8 | hSpCas9 | negative selection | 5436973 | 2267735 | 2267758 | 16 | + | 27661255 | K562 | viability | GCCCGGCGGGAGGGCCCCAAGGG | RNPS1 | ENSG00000205937 | -0.23530580771362453 | [207,317] | [188,166] | -6 | dCas9-KRAB | negative selection | 5508119 | 2267667 | 2267690 | 16 | - | 27661255 | K562 | viability | GCGGCCCGGCGCCTGGACGGGGG | RNPS1 | ENSG00000205937 | -0.014920507427879426 | [399,374] | [330,285] | 0 | dCas9-KRAB | negative selection | 5508120 | 2267993 | 2268016 | 16 | - | 27661255 | K562 | viability | GGCTGCCCGGCAGGCCCGGCAGG | RNPS1 | ENSG00000205937 | -0.026566404139494626 | [508,531] | [375,434] | -1 | dCas9-KRAB | negative selection | 5508121 | 2268045 | 2268068 | 16 | - | 27661255 | K562 | viability | GCGGCGGGAAGATGTAAGTTGGG | RNPS1 | ENSG00000205937 | -0.6914615565222517 | [107,194] | [98,52] | -8 | dCas9-KRAB | negative selection | 5508122 | 2262419 | 2262442 | 16 | - | 27260156 | BXPC3 | viability | TTCCCTCTAGGATCACATCATGG | RNPS1 | ENSG00000205937 | -0.9839416595979897 | [755] | [377,435,419,356] | -9 | hSpCas9 | negative selection | 5567821 | 2262733 | 2262756 | 16 | + | 27260156 | BXPC3 | viability | TCCTCACCTTTGTCACATTCCGG | RNPS1 | ENSG00000205937 | 0.18205745580416322 | [1973] | [1817,2179,2580,2912] | 4 | hSpCas9 | negative selection | 5567823 | 2263195 | 2263218 | 16 | - | 27260156 | BXPC3 | viability | TCCTCAGCATCCAGCCGCTCAGG | RNPS1 | ENSG00000205937 | -0.1548639279925832 | [1046] | [802,1052,831,1288] | -4 | hSpCas9 | negative selection | 5632075 | 2262739 | 2262762 | 16 | - | 27260156 | BXPC3 | viability | ACTCACCCGGAATGTGACAAAGG | RNPS1 | ENSG00000205937 | -2.2831678754723295 | [516] | [107,127,90,115] | -9 | hSpCas9 | negative selection | 5632076 | 2264191 | 2264214 | 16 | - | 27260156 | BXPC3 | viability | AAGAGGCGCAGCGCTTCCAGTGG | RNPS1 | ENSG00000205937 | -0.554101366922664 | [48] | [15,65,24,31] | -8 | hSpCas9 | negative selection | 5632077 | 2262419 | 2262442 | 16 | - | 27260156 | A673 | viability | TTCCCTCTAGGATCACATCATGG | RNPS1 | ENSG00000205937 | -0.5156909523526566 | [755] | [657,601,542,745] | -8 | hSpCas9 | negative selection | 5689072 | 2262733 | 2262756 | 16 | + | 27260156 | A673 | viability | TCCTCACCTTTGTCACATTCCGG | RNPS1 | ENSG00000205937 | 0.2019387249125475 | [1973] | [2980,2499,2891,2550] | 5 | hSpCas9 | negative selection | 5689074 | 2263195 | 2263218 | 16 | - | 27260156 | A673 | viability | TCCTCAGCATCCAGCCGCTCAGG | RNPS1 | ENSG00000205937 | -0.31213224017285135 | [1046] | [1128,959,911,1065] | -6 | hSpCas9 | negative selection | 5753326 | 2262739 | 2262762 | 16 | - | 27260156 | A673 | viability | ACTCACCCGGAATGTGACAAAGG | RNPS1 | ENSG00000205937 | -1.4161079597839619 | [516] | [242,174,270,243] | -9 | hSpCas9 | negative selection | 5753327 | 2264191 | 2264214 | 16 | - | 27260156 | A673 | viability | AAGAGGCGCAGCGCTTCCAGTGG | RNPS1 | ENSG00000205937 | -0.17168023938822596 | [48] | [72,42,65,27] | -4 | hSpCas9 | negative selection | 5753328 | 2262419 | 2262442 | 16 | - | 27260156 | A375 | viability | TTCCCTCTAGGATCACATCATGG | RNPS1 | ENSG00000205937 | -1.6916709096100886 | [755] | [366,164,346,206] | -9 | hSpCas9 | negative selection | 5810323 | 2262733 | 2262756 | 16 | + | 27260156 | A375 | viability | TCCTCACCTTTGTCACATTCCGG | RNPS1 | ENSG00000205937 | 0.0964293315466116 | [1973] | [2790,2915,2247,2014] | 1 | hSpCas9 | negative selection | 5810325 | 2263195 | 2263218 | 16 | - | 27260156 | A375 | viability | TCCTCAGCATCCAGCCGCTCAGG | RNPS1 | ENSG00000205937 | -0.5383167852718458 | [1046] | [669,986,1015,724] | -6 | hSpCas9 | negative selection | 5874577 | 2262739 | 2262762 | 16 | - | 27260156 | A375 | viability | ACTCACCCGGAATGTGACAAAGG | RNPS1 | ENSG00000205937 | -2.185676935635634 | [516] | [188,86,92,152] | -9 | hSpCas9 | negative selection | 5874578 | 2264191 | 2264214 | 16 | - | 27260156 | A375 | viability | AAGAGGCGCAGCGCTTCCAGTGG | RNPS1 | ENSG00000205937 | -5.249344229765194 | [48] | [0,0,2,0] | -9 | hSpCas9 | negative selection | 5874579 | 2262419 | 2262442 | 16 | - | 27260156 | COLO741 | viability | TTCCCTCTAGGATCACATCATGG | RNPS1 | ENSG00000205937 | -1.0141569815611782 | [755] | [446,364,608] | -9 | hSpCas9 | negative selection | 5931574 | 2262733 | 2262756 | 16 | + | 27260156 | COLO741 | viability | TCCTCACCTTTGTCACATTCCGG | RNPS1 | ENSG00000205937 | 0.2579029370167918 | [1973] | [3407,3076,2618] | 5 | hSpCas9 | negative selection | 5931576 | 2263195 | 2263218 | 16 | - | 27260156 | COLO741 | viability | TCCTCAGCATCCAGCCGCTCAGG | RNPS1 | ENSG00000205937 | -0.4905367435879866 | [1046] | [1177,839,861] | -8 | hSpCas9 | negative selection | 5995828 | 2262739 | 2262762 | 16 | - | 27260156 | COLO741 | viability | ACTCACCCGGAATGTGACAAAGG | RNPS1 | ENSG00000205937 | -1.9503688703291187 | [516] | [233,159,126] | -9 | hSpCas9 | negative selection | 5995829 | 2264191 | 2264214 | 16 | - | 27260156 | COLO741 | viability | AAGAGGCGCAGCGCTTCCAGTGG | RNPS1 | ENSG00000205937 | -1.7585974943634501 | [48] | [17,12,23] | -9 | hSpCas9 | negative selection | 5995830 | 2262419 | 2262442 | 16 | - | 27260156 | CAL120 | viability | TTCCCTCTAGGATCACATCATGG | RNPS1 | ENSG00000205937 | -1.6749372742832689 | [755] | [286,266,327] | -9 | hSpCas9 | negative selection | 6052825 | 2262733 | 2262756 | 16 | + | 27260156 | CAL120 | viability | TCCTCACCTTTGTCACATTCCGG | RNPS1 | ENSG00000205937 | 0.39368116092930316 | [1973] | [3846,2909,3019] | 6 | hSpCas9 | negative selection | 6052827 | 2263195 | 2263218 | 16 | - | 27260156 | CAL120 | viability | TCCTCAGCATCCAGCCGCTCAGG | RNPS1 | ENSG00000205937 | -0.6749472464038114 | [1046] | [831,564,1048] | -7 | hSpCas9 | negative selection | 6117079 | 2262739 | 2262762 | 16 | - | 27260156 | CAL120 | viability | ACTCACCCGGAATGTGACAAAGG | RNPS1 | ENSG00000205937 | -2.3665300516137378 | [516] | [174,150,56] | -9 | hSpCas9 | negative selection | 6117080 | 2264191 | 2264214 | 16 | - | 27260156 | CAL120 | viability | AAGAGGCGCAGCGCTTCCAGTGG | RNPS1 | ENSG00000205937 | -1.7355993676126897 | [48] | [1,5,43] | -9 | hSpCas9 | negative selection | 6117081 | 2262419 | 2262442 | 16 | - | 27260156 | CADOES1 | viability | TTCCCTCTAGGATCACATCATGG | RNPS1 | ENSG00000205937 | -0.8007599803970875 | [755] | [183,425,653,348] | -8 | hSpCas9 | negative selection | 6174076 | 2262733 | 2262756 | 16 | + | 27260156 | CADOES1 | viability | TCCTCACCTTTGTCACATTCCGG | RNPS1 | ENSG00000205937 | 0.40592839626181965 | [1973] | [2243,2055,2680,2760] | 6 | hSpCas9 | negative selection | 6174078 | 2263195 | 2263218 | 16 | - | 27260156 | CADOES1 | viability | TCCTCAGCATCCAGCCGCTCAGG | RNPS1 | ENSG00000205937 | -0.3119915259629079 | [1046] | [795,953,780,599] | -5 | hSpCas9 | negative selection | 6238330 | 2262739 | 2262762 | 16 | - | 27260156 | CADOES1 | viability | ACTCACCCGGAATGTGACAAAGG | RNPS1 | ENSG00000205937 | -1.0984525664200397 | [516] | [186,143,116,458] | -9 | hSpCas9 | negative selection | 6238331 | 2264191 | 2264214 | 16 | - | 27260156 | CADOES1 | viability | AAGAGGCGCAGCGCTTCCAGTGG | RNPS1 | ENSG00000205937 | -2.3053249738173727 | [48] | [11,1,9,12] | -9 | hSpCas9 | negative selection | 6238332 | 2262419 | 2262442 | 16 | - | 27260156 | EWS502 | viability | TTCCCTCTAGGATCACATCATGG | RNPS1 | ENSG00000205937 | -1.992446651659544 | [755] | [96,227,257,235] | -9 | hSpCas9 | negative selection | 6295327 | 2262733 | 2262756 | 16 | + | 27260156 | EWS502 | viability | TCCTCACCTTTGTCACATTCCGG | RNPS1 | ENSG00000205937 | 0.6385215017823733 | [1973] | [3018,3010,3452,3588] | 9 | hSpCas9 | negative selection | 6295329 | 2263195 | 2263218 | 16 | - | 27260156 | EWS502 | viability | TCCTCAGCATCCAGCCGCTCAGG | RNPS1 | ENSG00000205937 | -0.4390701658561431 | [1046] | [792,1013,816,625] | -6 | hSpCas9 | negative selection | 6359581 | 2262739 | 2262762 | 16 | - | 27260156 | EWS502 | viability | ACTCACCCGGAATGTGACAAAGG | RNPS1 | ENSG00000205937 | -2.532912253801927 | [516] | [64,81,122,113] | -9 | hSpCas9 | negative selection | 6359582 | 2264191 | 2264214 | 16 | - | 27260156 | EWS502 | viability | AAGAGGCGCAGCGCTTCCAGTGG | RNPS1 | ENSG00000205937 | -2.215391084469029 | [48] | [3,11,27,0] | -9 | hSpCas9 | negative selection | 6359583 | 2262419 | 2262442 | 16 | - | 27260156 | EW8 | viability | TTCCCTCTAGGATCACATCATGG | RNPS1 | ENSG00000205937 | -1.12042154149017 | [755] | [288,258,245,338] | -9 | hSpCas9 | negative selection | 6416578 | 2262733 | 2262756 | 16 | + | 27260156 | EW8 | viability | TCCTCACCTTTGTCACATTCCGG | RNPS1 | ENSG00000205937 | 0.25056687712417647 | [1973] | [2183,1931,1555,2024] | 4 | hSpCas9 | negative selection | 6416580 | 2263195 | 2263218 | 16 | - | 27260156 | EW8 | viability | TCCTCAGCATCCAGCCGCTCAGG | RNPS1 | ENSG00000205937 | -0.4475492382917241 | [1046] | [716,508,524,761] | -7 | hSpCas9 | negative selection | 6480832 | 2262739 | 2262762 | 16 | - | 27260156 | EW8 | viability | ACTCACCCGGAATGTGACAAAGG | RNPS1 | ENSG00000205937 | -2.1495014301829105 | [516] | [93,95,132,47] | -9 | hSpCas9 | negative selection | 6480833 | 2264191 | 2264214 | 16 | - | 27260156 | EW8 | viability | AAGAGGCGCAGCGCTTCCAGTGG | RNPS1 | ENSG00000205937 | -1.954874184680229 | [48] | [17,6,2,14] | -9 | hSpCas9 | negative selection | 6480834 | 2262419 | 2262442 | 16 | - | 27260156 | CORL105 | viability | TTCCCTCTAGGATCACATCATGG | RNPS1 | ENSG00000205937 | -1.0200981972711778 | [755] | [376,412,401,545] | -9 | hSpCas9 | negative selection | 6537829 | 2262733 | 2262756 | 16 | + | 27260156 | CORL105 | viability | TCCTCACCTTTGTCACATTCCGG | RNPS1 | ENSG00000205937 | 0.028326517256799466 | [1973] | [2168,2405,2786,2124] | 0 | hSpCas9 | negative selection | 6537831 | 2263195 | 2263218 | 16 | - | 27260156 | CORL105 | viability | TCCTCAGCATCCAGCCGCTCAGG | RNPS1 | ENSG00000205937 | -0.1712184497465088 | [1046] | [1155,1092,1217,909] | -3 | hSpCas9 | negative selection | 6602083 | 2262739 | 2262762 | 16 | - | 27260156 | CORL105 | viability | ACTCACCCGGAATGTGACAAAGG | RNPS1 | ENSG00000205937 | -1.9530945609234838 | [516] | [137,204,132,143] | -9 | hSpCas9 | negative selection | 6602084 | 2264191 | 2264214 | 16 | - | 27260156 | CORL105 | viability | AAGAGGCGCAGCGCTTCCAGTGG | RNPS1 | ENSG00000205937 | -1.400710532696586 | [48] | [27,4,12,39] | -9 | hSpCas9 | negative selection | 6602085 | 2262419 | 2262442 | 16 | - | 27260156 | HS294T | viability | TTCCCTCTAGGATCACATCATGG | RNPS1 | ENSG00000205937 | -0.7534667435356153 | [755] | [184,166,146,196] | -8 | hSpCas9 | negative selection | 6659080 | 2262733 | 2262756 | 16 | + | 27260156 | HS294T | viability | TCCTCACCTTTGTCACATTCCGG | RNPS1 | ENSG00000205937 | 0.43555108001137244 | [1973] | [868,1153,927,1216] | 6 | hSpCas9 | negative selection | 6659082 | 2263195 | 2263218 | 16 | - | 27260156 | HS294T | viability | TCCTCAGCATCCAGCCGCTCAGG | RNPS1 | ENSG00000205937 | -0.7575754024304651 | [1046] | [220,206,236,305] | -8 | hSpCas9 | negative selection | 6723334 | 2262739 | 2262762 | 16 | - | 27260156 | HS294T | viability | ACTCACCCGGAATGTGACAAAGG | RNPS1 | ENSG00000205937 | -2.9489475570852237 | [516] | [20,14,28,41] | -9 | hSpCas9 | negative selection | 6723335 | 2264191 | 2264214 | 16 | - | 27260156 | HS294T | viability | AAGAGGCGCAGCGCTTCCAGTGG | RNPS1 | ENSG00000205937 | -2.1007745328708283 | [48] | [0,1,5,9] | -9 | hSpCas9 | negative selection | 6723336 | 2262419 | 2262442 | 16 | - | 27260156 | HCC44 | viability | TTCCCTCTAGGATCACATCATGG | RNPS1 | ENSG00000205937 | -2.169127185286487 | [755] | [206,164,186,203] | -9 | hSpCas9 | negative selection | 6780331 | 2262733 | 2262756 | 16 | + | 27260156 | HCC44 | viability | TCCTCACCTTTGTCACATTCCGG | RNPS1 | ENSG00000205937 | 0.4095526606966833 | [1973] | [2703,2290,4174,2948] | 6 | hSpCas9 | negative selection | 6780333 | 2263195 | 2263218 | 16 | - | 27260156 | HCC44 | viability | TCCTCAGCATCCAGCCGCTCAGG | RNPS1 | ENSG00000205937 | -0.8337205078184908 | [1046] | [702,534,906,573] | -8 | hSpCas9 | negative selection | 6844585 | 2262739 | 2262762 | 16 | - | 27260156 | HCC44 | viability | ACTCACCCGGAATGTGACAAAGG | RNPS1 | ENSG00000205937 | -3.6986542573282346 | [516] | [88,62,18,6] | -9 | hSpCas9 | negative selection | 6844586 | 2264191 | 2264214 | 16 | - | 27260156 | HCC44 | viability | AAGAGGCGCAGCGCTTCCAGTGG | RNPS1 | ENSG00000205937 | -1.740070231821353 | [48] | [11,0,19,34] | -9 | hSpCas9 | negative selection | 6844587 | 2262419 | 2262442 | 16 | - | 27260156 | G402 | viability | TTCCCTCTAGGATCACATCATGG | RNPS1 | ENSG00000205937 | -1.544419558179817 | [755] | [187,483,329,255] | -9 | hSpCas9 | negative selection | 6901582 | 2262733 | 2262756 | 16 | + | 27260156 | G402 | viability | TCCTCACCTTTGTCACATTCCGG | RNPS1 | ENSG00000205937 | 0.3095367024301212 | [1973] | [2873,2864,3313,2858] | 4 | hSpCas9 | negative selection | 6901584 | 2263195 | 2263218 | 16 | - | 27260156 | G402 | viability | TCCTCAGCATCCAGCCGCTCAGG | RNPS1 | ENSG00000205937 | -0.4367897135421739 | [1046] | [837,788,1041,1071] | -5 | hSpCas9 | negative selection | 6965836 | 2262739 | 2262762 | 16 | - | 27260156 | G402 | viability | ACTCACCCGGAATGTGACAAAGG | RNPS1 | ENSG00000205937 | -2.348086873441687 | [516] | [199,198,40,72] | -9 | hSpCas9 | negative selection | 6965837 | 2264191 | 2264214 | 16 | - | 27260156 | G402 | viability | AAGAGGCGCAGCGCTTCCAGTGG | RNPS1 | ENSG00000205937 | -4.40487799520284 | [48] | [0,0,7,0] | -9 | hSpCas9 | negative selection | 6965838 | 2262419 | 2262442 | 16 | - | 27260156 | L33 | viability | TTCCCTCTAGGATCACATCATGG | RNPS1 | ENSG00000205937 | -0.37889310916356705 | [755] | [540,282,316,589] | -7 | hSpCas9 | negative selection | 7022833 | 2262733 | 2262756 | 16 | + | 27260156 | L33 | viability | TCCTCACCTTTGTCACATTCCGG | RNPS1 | ENSG00000205937 | 0.3539582358781237 | [1973] | [2502,955,1633,2654] | 7 | hSpCas9 | negative selection | 7022835 | 2263195 | 2263218 | 16 | - | 27260156 | L33 | viability | TCCTCAGCATCCAGCCGCTCAGG | RNPS1 | ENSG00000205937 | -0.6102633307200549 | [1046] | [709,233,439,760] | -8 | hSpCas9 | negative selection | 7087087 | 2262739 | 2262762 | 16 | - | 27260156 | L33 | viability | ACTCACCCGGAATGTGACAAAGG | RNPS1 | ENSG00000205937 | -2.184885576132892 | [516] | [87,58,41,155] | -9 | hSpCas9 | negative selection | 7087088 | 2264191 | 2264214 | 16 | - | 27260156 | L33 | viability | AAGAGGCGCAGCGCTTCCAGTGG | RNPS1 | ENSG00000205937 | -0.6207342423041515 | [48] | [9,17,14,49] | -9 | hSpCas9 | negative selection | 7087089 | 2262419 | 2262442 | 16 | - | 27260156 | K562 | viability | TTCCCTCTAGGATCACATCATGG | RNPS1 | ENSG00000205937 | -1.7411767118101482 | [755] | [140,306,223,137] | -9 | hSpCas9 | negative selection | 7144084 | 2262733 | 2262756 | 16 | + | 27260156 | K562 | viability | TCCTCACCTTTGTCACATTCCGG | RNPS1 | ENSG00000205937 | 0.8497407685415368 | [1973] | [3609,2661,3529,2858] | 9 | hSpCas9 | negative selection | 7144086 | 2263195 | 2263218 | 16 | - | 27260156 | K562 | viability | TCCTCAGCATCCAGCCGCTCAGG | RNPS1 | ENSG00000205937 | -0.5915145919111605 | [1046] | [553,871,484,566] | -6 | hSpCas9 | negative selection | 7208338 | 2262739 | 2262762 | 16 | - | 27260156 | K562 | viability | ACTCACCCGGAATGTGACAAAGG | RNPS1 | ENSG00000205937 | -3.343304412397998 | [516] | [56,15,32,70] | -9 | hSpCas9 | negative selection | 7208339 | 2264191 | 2264214 | 16 | - | 27260156 | K562 | viability | AAGAGGCGCAGCGCTTCCAGTGG | RNPS1 | ENSG00000205937 | -4.087142007646101 | [48] | [0,3,0,3] | -9 | hSpCas9 | negative selection | 7208340 | 2262419 | 2262442 | 16 | - | 27260156 | HT29 | viability | TTCCCTCTAGGATCACATCATGG | RNPS1 | ENSG00000205937 | -2.1312691872432294 | [755] | [269,165,170,228] | -9 | hSpCas9 | negative selection | 7265335 | 2262733 | 2262756 | 16 | + | 27260156 | HT29 | viability | TCCTCACCTTTGTCACATTCCGG | RNPS1 | ENSG00000205937 | 0.5072568795529673 | [1973] | [3712,3624,3498,2887] | 8 | hSpCas9 | negative selection | 7265337 | 2263195 | 2263218 | 16 | - | 27260156 | HT29 | viability | TCCTCAGCATCCAGCCGCTCAGG | RNPS1 | ENSG00000205937 | -0.3641344625362073 | [1046] | [1220,1202,720,855] | -6 | hSpCas9 | negative selection | 7329589 | 2262739 | 2262762 | 16 | - | 27260156 | HT29 | viability | ACTCACCCGGAATGTGACAAAGG | RNPS1 | ENSG00000205937 | -2.044998277335075 | [516] | [170,145,157,135] | -9 | hSpCas9 | negative selection | 7329590 | 2264191 | 2264214 | 16 | - | 27260156 | HT29 | viability | AAGAGGCGCAGCGCTTCCAGTGG | RNPS1 | ENSG00000205937 | -1.0197291768788044 | [48] | [15,48,23,28] | -8 | hSpCas9 | negative selection | 7329591 | 2262419 | 2262442 | 16 | - | 27260156 | MHHES1 | viability | TTCCCTCTAGGATCACATCATGG | RNPS1 | ENSG00000205937 | -0.5219912109921859 | [755] | [864,638,576,367] | -7 | hSpCas9 | negative selection | 7386586 | 2262733 | 2262756 | 16 | + | 27260156 | MHHES1 | viability | TCCTCACCTTTGTCACATTCCGG | RNPS1 | ENSG00000205937 | 0.10376088207633893 | [1973] | [2793,2576,2105,2146] | 2 | hSpCas9 | negative selection | 7386588 | 2263195 | 2263218 | 16 | - | 27260156 | MHHES1 | viability | TCCTCAGCATCCAGCCGCTCAGG | RNPS1 | ENSG00000205937 | -0.4602770751606595 | [1046] | [860,910,1068,628] | -7 | hSpCas9 | negative selection | 7450840 | 2262739 | 2262762 | 16 | - | 27260156 | MHHES1 | viability | ACTCACCCGGAATGTGACAAAGG | RNPS1 | ENSG00000205937 | -2.0617375704596554 | [516] | [140,154,164,103] | -9 | hSpCas9 | negative selection | 7450841 | 2264191 | 2264214 | 16 | - | 27260156 | MHHES1 | viability | AAGAGGCGCAGCGCTTCCAGTGG | RNPS1 | ENSG00000205937 | -0.9860030922962673 | [48] | [63,20,4,24] | -9 | hSpCas9 | negative selection | 7450842 | 2262419 | 2262442 | 16 | - | 27260156 | MEWO | viability | TTCCCTCTAGGATCACATCATGG | RNPS1 | ENSG00000205937 | -0.7444585825384901 | [755] | [573,388,332] | -9 | hSpCas9 | negative selection | 7507837 | 2262733 | 2262756 | 16 | + | 27260156 | MEWO | viability | TCCTCACCTTTGTCACATTCCGG | RNPS1 | ENSG00000205937 | 0.4872266308449542 | [1973] | [2879,2811,2128] | 8 | hSpCas9 | negative selection | 7507839 | 2263195 | 2263218 | 16 | - | 27260156 | MEWO | viability | TCCTCAGCATCCAGCCGCTCAGG | RNPS1 | ENSG00000205937 | -0.39893044216037554 | [1046] | [824,626,792] | -7 | hSpCas9 | negative selection | 7572091 | 2262739 | 2262762 | 16 | - | 27260156 | MEWO | viability | ACTCACCCGGAATGTGACAAAGG | RNPS1 | ENSG00000205937 | -1.703512585710985 | [516] | [115,188,133] | -9 | hSpCas9 | negative selection | 7572092 | 2264191 | 2264214 | 16 | - | 27260156 | MEWO | viability | AAGAGGCGCAGCGCTTCCAGTGG | RNPS1 | ENSG00000205937 | -0.1042941527300818 | [48] | [27,60,35] | -2 | hSpCas9 | negative selection | 7572093 | 2262419 | 2262442 | 16 | - | 27260156 | LNCAPCLONEFGC | viability | TTCCCTCTAGGATCACATCATGG | RNPS1 | ENSG00000205937 | -1.0167381502542296 | [755] | [405,253,446,266] | -8 | hSpCas9 | negative selection | 7629088 | 2262733 | 2262756 | 16 | + | 27260156 | LNCAPCLONEFGC | viability | TCCTCACCTTTGTCACATTCCGG | RNPS1 | ENSG00000205937 | 0.5387974992326301 | [1973] | [2636,2412,2895,2498] | 8 | hSpCas9 | negative selection | 7629090 | 2263195 | 2263218 | 16 | - | 27260156 | LNCAPCLONEFGC | viability | TCCTCAGCATCCAGCCGCTCAGG | RNPS1 | ENSG00000205937 | -0.3572431280283155 | [1046] | [890,649,752,671] | -5 | hSpCas9 | negative selection | 7693342 | 2262739 | 2262762 | 16 | - | 27260156 | LNCAPCLONEFGC | viability | ACTCACCCGGAATGTGACAAAGG | RNPS1 | ENSG00000205937 | -1.9293673108632787 | [516] | [138,119,111,118] | -9 | hSpCas9 | negative selection | 7693343 | 2264191 | 2264214 | 16 | - | 27260156 | LNCAPCLONEFGC | viability | AAGAGGCGCAGCGCTTCCAGTGG | RNPS1 | ENSG00000205937 | -3.363975063649734 | [48] | [0,5,2,6] | -9 | hSpCas9 | negative selection | 7693344 | 2262419 | 2262442 | 16 | - | 27260156 | PANC0327 | viability | TTCCCTCTAGGATCACATCATGG | RNPS1 | ENSG00000205937 | -1.0982404232759044 | [755] | [442,183,339,314] | -8 | hSpCas9 | negative selection | 7750339 | 2262733 | 2262756 | 16 | + | 27260156 | PANC0327 | viability | TCCTCACCTTTGTCACATTCCGG | RNPS1 | ENSG00000205937 | 0.11172918326540282 | [1973] | [1842,1702,2049,2002] | 1 | hSpCas9 | negative selection | 7750341 | 2263195 | 2263218 | 16 | - | 27260156 | PANC0327 | viability | TCCTCAGCATCCAGCCGCTCAGG | RNPS1 | ENSG00000205937 | -0.9138998877892383 | [1046] | [794,400,432,381] | -8 | hSpCas9 | negative selection | 7814593 | 2262739 | 2262762 | 16 | - | 27260156 | PANC0327 | viability | ACTCACCCGGAATGTGACAAAGG | RNPS1 | ENSG00000205937 | -2.917122705863638 | [516] | [83,29,36,97] | -9 | hSpCas9 | negative selection | 7814594 | 2264191 | 2264214 | 16 | - | 27260156 | PANC0327 | viability | AAGAGGCGCAGCGCTTCCAGTGG | RNPS1 | ENSG00000205937 | -3.414156865705857 | [48] | [8,1,1,3] | -9 | hSpCas9 | negative selection | 7814595 | 2262419 | 2262442 | 16 | - | 27260156 | NCIH2009 | viability | TTCCCTCTAGGATCACATCATGG | RNPS1 | ENSG00000205937 | -2.351908687734866 | [755] | [176,286,148] | -9 | hSpCas9 | negative selection | 7871590 | 2262733 | 2262756 | 16 | + | 27260156 | NCIH2009 | viability | TCCTCACCTTTGTCACATTCCGG | RNPS1 | ENSG00000205937 | 0.2824021611944034 | [1973] | [3918,2850,3407] | 4 | hSpCas9 | negative selection | 7871592 | 2263195 | 2263218 | 16 | - | 27260156 | NCIH2009 | viability | TCCTCAGCATCCAGCCGCTCAGG | RNPS1 | ENSG00000205937 | -0.7787753548895652 | [1046] | [1037,800,754] | -7 | hSpCas9 | negative selection | 7935844 | 2262739 | 2262762 | 16 | - | 27260156 | NCIH2009 | viability | ACTCACCCGGAATGTGACAAAGG | RNPS1 | ENSG00000205937 | -2.365244390398009 | [516] | [114,104,195] | -9 | hSpCas9 | negative selection | 7935845 | 2264191 | 2264214 | 16 | - | 27260156 | NCIH2009 | viability | AAGAGGCGCAGCGCTTCCAGTGG | RNPS1 | ENSG00000205937 | -2.1133808948865345 | [48] | [14,30,0] | -9 | hSpCas9 | negative selection | 7935846 | 2262419 | 2262442 | 16 | - | 27260156 | NCIH1373 | viability | TTCCCTCTAGGATCACATCATGG | RNPS1 | ENSG00000205937 | -1.8053646364238467 | [755] | [173,179,171,118] | -9 | hSpCas9 | negative selection | 7992841 | 2262733 | 2262756 | 16 | + | 27260156 | NCIH1373 | viability | TCCTCACCTTTGTCACATTCCGG | RNPS1 | ENSG00000205937 | 0.7280294604705371 | [1973] | [3216,4481,3890,744] | 7 | hSpCas9 | negative selection | 7992843 | 2263195 | 2263218 | 16 | - | 27260156 | NCIH1373 | viability | TCCTCAGCATCCAGCCGCTCAGG | RNPS1 | ENSG00000205937 | -0.5819242070775508 | [1046] | [1135,848,603,152] | -5 | hSpCas9 | negative selection | 8057095 | 2262739 | 2262762 | 16 | - | 27260156 | NCIH1373 | viability | ACTCACCCGGAATGTGACAAAGG | RNPS1 | ENSG00000205937 | -2.6429823461246413 | [516] | [27,21,230,21] | -9 | hSpCas9 | negative selection | 8057096 | 2264191 | 2264214 | 16 | - | 27260156 | NCIH1373 | viability | AAGAGGCGCAGCGCTTCCAGTGG | RNPS1 | ENSG00000205937 | -4.183792506110159 | [48] | [2,0,0,1] | -9 | hSpCas9 | negative selection | 8057097 | 2262419 | 2262442 | 16 | - | 27260156 | PATU8902 | viability | TTCCCTCTAGGATCACATCATGG | RNPS1 | ENSG00000205937 | -2.042442108298702 | [755] | [146,434,277,142] | -9 | hSpCas9 | negative selection | 8114092 | 2262733 | 2262756 | 16 | + | 27260156 | PATU8902 | viability | TCCTCACCTTTGTCACATTCCGG | RNPS1 | ENSG00000205937 | 0.2919070573045546 | [1973] | [3041,3661,2659,4381] | 3 | hSpCas9 | negative selection | 8114094 | 2263195 | 2263218 | 16 | - | 27260156 | PATU8902 | viability | TCCTCAGCATCCAGCCGCTCAGG | RNPS1 | ENSG00000205937 | -0.2838472163539181 | [1046] | [1671,1384,711,1123] | -3 | hSpCas9 | negative selection | 8178346 | 2262739 | 2262762 | 16 | - | 27260156 | PATU8902 | viability | ACTCACCCGGAATGTGACAAAGG | RNPS1 | ENSG00000205937 | -4.5166840178991645 | [516] | [7,46,56,3] | -9 | hSpCas9 | negative selection | 8178347 | 2264191 | 2264214 | 16 | - | 27260156 | PATU8902 | viability | AAGAGGCGCAGCGCTTCCAGTGG | RNPS1 | ENSG00000205937 | -5.779234568069954 | [48] | [0,1,0,0] | -9 | hSpCas9 | negative selection | 8178348 | 2262419 | 2262442 | 16 | - | 27260156 | PANC1 | viability | TTCCCTCTAGGATCACATCATGG | RNPS1 | ENSG00000205937 | -3.1109768409391267 | [755] | [83,72,48,89] | -9 | hSpCas9 | negative selection | 8235343 | 2262733 | 2262756 | 16 | + | 27260156 | PANC1 | viability | TCCTCACCTTTGTCACATTCCGG | RNPS1 | ENSG00000205937 | 0.08438494600875979 | [1973] | [1814,2199,1926,1372] | 1 | hSpCas9 | negative selection | 8235345 | 2263195 | 2263218 | 16 | - | 27260156 | PANC1 | viability | TCCTCAGCATCCAGCCGCTCAGG | RNPS1 | ENSG00000205937 | -0.7584879821407905 | [1046] | [396,681,670,420] | -8 | hSpCas9 | negative selection | 8299597 | 2262739 | 2262762 | 16 | - | 27260156 | PANC1 | viability | ACTCACCCGGAATGTGACAAAGG | RNPS1 | ENSG00000205937 | -2.7981111946545765 | [516] | [102,30,11,94] | -9 | hSpCas9 | negative selection | 8299598 | 2264191 | 2264214 | 16 | - | 27260156 | PANC1 | viability | AAGAGGCGCAGCGCTTCCAGTGG | RNPS1 | ENSG00000205937 | -2.301861795029603 | [48] | [1,35,1,0] | -9 | hSpCas9 | negative selection | 8299599 | 2262419 | 2262442 | 16 | - | 27260156 | PANC0813 | viability | TTCCCTCTAGGATCACATCATGG | RNPS1 | ENSG00000205937 | -1.6299167349706494 | [755] | [337,311,255,247] | -9 | hSpCas9 | negative selection | 8356594 | 2262733 | 2262756 | 16 | + | 27260156 | PANC0813 | viability | TCCTCACCTTTGTCACATTCCGG | RNPS1 | ENSG00000205937 | 0.35794667787094214 | [1973] | [3150,2900,3165,2696] | 6 | hSpCas9 | negative selection | 8356596 | 2263195 | 2263218 | 16 | - | 27260156 | PANC0813 | viability | TCCTCAGCATCCAGCCGCTCAGG | RNPS1 | ENSG00000205937 | -0.42447450452527946 | [1046] | [941,882,1003,841] | -6 | hSpCas9 | negative selection | 8420848 | 2262739 | 2262762 | 16 | - | 27260156 | PANC0813 | viability | ACTCACCCGGAATGTGACAAAGG | RNPS1 | ENSG00000205937 | -2.2903660259864185 | [516] | [102,38,91,252] | -9 | hSpCas9 | negative selection | 8420849 | 2264191 | 2264214 | 16 | - | 27260156 | PANC0813 | viability | AAGAGGCGCAGCGCTTCCAGTGG | RNPS1 | ENSG00000205937 | -2.5489864915319935 | [48] | [10,4,22,0] | -9 | hSpCas9 | negative selection | 8420850 | 2262419 | 2262442 | 16 | - | 27260156 | RDES | viability | TTCCCTCTAGGATCACATCATGG | RNPS1 | ENSG00000205937 | -1.4424043225453922 | [755] | [287,266,357,378] | -9 | hSpCas9 | negative selection | 8477845 | 2262733 | 2262756 | 16 | + | 27260156 | RDES | viability | TCCTCACCTTTGTCACATTCCGG | RNPS1 | ENSG00000205937 | 0.5884502621408152 | [1973] | [2908,2863,4019,4036] | 8 | hSpCas9 | negative selection | 8477847 | 2263195 | 2263218 | 16 | - | 27260156 | RDES | viability | TCCTCAGCATCCAGCCGCTCAGG | RNPS1 | ENSG00000205937 | -0.14822685671392044 | [1046] | [908,931,1328,1226] | -2 | hSpCas9 | negative selection | 8542099 | 2262739 | 2262762 | 16 | - | 27260156 | RDES | viability | ACTCACCCGGAATGTGACAAAGG | RNPS1 | ENSG00000205937 | -2.0034193628619312 | [516] | [83,141,189,196] | -9 | hSpCas9 | negative selection | 8542100 | 2264191 | 2264214 | 16 | - | 27260156 | RDES | viability | AAGAGGCGCAGCGCTTCCAGTGG | RNPS1 | ENSG00000205937 | -1.2471418843369482 | [48] | [16,21,20,37] | -9 | hSpCas9 | negative selection | 8542101 | 2262419 | 2262442 | 16 | - | 27260156 | PC3 | viability | TTCCCTCTAGGATCACATCATGG | RNPS1 | ENSG00000205937 | -0.38839205551709194 | [755] | [364,672,724,628] | -7 | hSpCas9 | negative selection | 8599096 | 2262733 | 2262756 | 16 | + | 27260156 | PC3 | viability | TCCTCACCTTTGTCACATTCCGG | RNPS1 | ENSG00000205937 | 0.47682957042180973 | [1973] | [1417,2838,4806,3055] | 8 | hSpCas9 | negative selection | 8599098 | 2263195 | 2263218 | 16 | - | 27260156 | PC3 | viability | TCCTCAGCATCCAGCCGCTCAGG | RNPS1 | ENSG00000205937 | -0.42236228876219184 | [1046] | [555,675,1112,924] | -7 | hSpCas9 | negative selection | 8663350 | 2262739 | 2262762 | 16 | - | 27260156 | PC3 | viability | ACTCACCCGGAATGTGACAAAGG | RNPS1 | ENSG00000205937 | -1.3116011231031637 | [516] | [187,214,296,141] | -9 | hSpCas9 | negative selection | 8663351 | 2264191 | 2264214 | 16 | - | 27260156 | PC3 | viability | AAGAGGCGCAGCGCTTCCAGTGG | RNPS1 | ENSG00000205937 | -2.5683929993492014 | [48] | [7,7,16,1] | -9 | hSpCas9 | negative selection | 8663352 | 2262419 | 2262442 | 16 | - | 27260156 | PATU8988T | viability | TTCCCTCTAGGATCACATCATGG | RNPS1 | ENSG00000205937 | -1.7832715429816057 | [755] | [226,318,76,239] | -9 | hSpCas9 | negative selection | 8720347 | 2262733 | 2262756 | 16 | + | 27260156 | PATU8988T | viability | TCCTCACCTTTGTCACATTCCGG | RNPS1 | ENSG00000205937 | 0.0854859652593003 | [1973] | [1960,2262,2035,1842] | 1 | hSpCas9 | negative selection | 8720349 | 2263195 | 2263218 | 16 | - | 27260156 | PATU8988T | viability | TCCTCAGCATCCAGCCGCTCAGG | RNPS1 | ENSG00000205937 | -0.5848329097042887 | [1046] | [833,618,745,476] | -7 | hSpCas9 | negative selection | 8784601 | 2262739 | 2262762 | 16 | - | 27260156 | PATU8988T | viability | ACTCACCCGGAATGTGACAAAGG | RNPS1 | ENSG00000205937 | -2.6138576911504505 | [516] | [47,64,72,143] | -9 | hSpCas9 | negative selection | 8784602 | 2264191 | 2264214 | 16 | - | 27260156 | PATU8988T | viability | AAGAGGCGCAGCGCTTCCAGTGG | RNPS1 | ENSG00000205937 | -1.9289968652715044 | [48] | [11,24,11,0] | -9 | hSpCas9 | negative selection | 8784603 | 2262419 | 2262442 | 16 | - | 27260156 | T47D | viability | TTCCCTCTAGGATCACATCATGG | RNPS1 | ENSG00000205937 | -1.10974251071787 | [755] | [418,333,470,413] | -9 | hSpCas9 | negative selection | 8841598 | 2262733 | 2262756 | 16 | + | 27260156 | T47D | viability | TCCTCACCTTTGTCACATTCCGG | RNPS1 | ENSG00000205937 | 0.45410187471352037 | [1973] | [3057,2981,3126,3457] | 8 | hSpCas9 | negative selection | 8841600 | 2263195 | 2263218 | 16 | - | 27260156 | T47D | viability | TCCTCAGCATCCAGCCGCTCAGG | RNPS1 | ENSG00000205937 | -0.23879052140615353 | [1046] | [879,966,1214,1075] | -5 | hSpCas9 | negative selection | 8905852 | 2262739 | 2262762 | 16 | - | 27260156 | T47D | viability | ACTCACCCGGAATGTGACAAAGG | RNPS1 | ENSG00000205937 | -2.003826203265457 | [516] | [120,183,176,113] | -9 | hSpCas9 | negative selection | 8905853 | 2264191 | 2264214 | 16 | - | 27260156 | T47D | viability | AAGAGGCGCAGCGCTTCCAGTGG | RNPS1 | ENSG00000205937 | -1.6278500955826467 | [48] | [22,14,21,13] | -9 | hSpCas9 | negative selection | 8905854 | 2262419 | 2262442 | 16 | - | 27260156 | SU8686 | viability | TTCCCTCTAGGATCACATCATGG | RNPS1 | ENSG00000205937 | -1.9829040794940003 | [755] | [136,175,269,182] | -9 | hSpCas9 | negative selection | 8962849 | 2262733 | 2262756 | 16 | + | 27260156 | SU8686 | viability | TCCTCACCTTTGTCACATTCCGG | RNPS1 | ENSG00000205937 | 0.5995198670269435 | [1973] | [2429,2738,3551,3275] | 8 | hSpCas9 | negative selection | 8962851 | 2263195 | 2263218 | 16 | - | 27260156 | SU8686 | viability | TCCTCAGCATCCAGCCGCTCAGG | RNPS1 | ENSG00000205937 | -0.2446151185664598 | [1046] | [799,754,939,1058] | -4 | hSpCas9 | negative selection | 9027103 | 2262739 | 2262762 | 16 | - | 27260156 | SU8686 | viability | ACTCACCCGGAATGTGACAAAGG | RNPS1 | ENSG00000205937 | -2.407495854550906 | [516] | [75,137,95,67] | -9 | hSpCas9 | negative selection | 9027104 | 2264191 | 2264214 | 16 | - | 27260156 | SU8686 | viability | AAGAGGCGCAGCGCTTCCAGTGG | RNPS1 | ENSG00000205937 | -3.0558384024115948 | [48] | [8,6,4,0] | -9 | hSpCas9 | negative selection | 9027105 | 2262419 | 2262442 | 16 | - | 27260156 | SKES1 | viability | TTCCCTCTAGGATCACATCATGG | RNPS1 | ENSG00000205937 | -0.6928812514118854 | [755] | [554,582,390,370] | -9 | hSpCas9 | negative selection | 9084100 | 2262733 | 2262756 | 16 | + | 27260156 | SKES1 | viability | TCCTCACCTTTGTCACATTCCGG | RNPS1 | ENSG00000205937 | 0.4000848058338571 | [1973] | [2831,3064,2590,2034] | 7 | hSpCas9 | negative selection | 9084102 | 2263195 | 2263218 | 16 | - | 27260156 | SKES1 | viability | TCCTCAGCATCCAGCCGCTCAGG | RNPS1 | ENSG00000205937 | -0.6070497964602627 | [1046] | [776,672,667,634] | -8 | hSpCas9 | negative selection | 9148354 | 2262739 | 2262762 | 16 | - | 27260156 | SKES1 | viability | ACTCACCCGGAATGTGACAAAGG | RNPS1 | ENSG00000205937 | -1.3551637247246995 | [516] | [228,204,195,180] | -9 | hSpCas9 | negative selection | 9148355 | 2264191 | 2264214 | 16 | - | 27260156 | SKES1 | viability | AAGAGGCGCAGCGCTTCCAGTGG | RNPS1 | ENSG00000205937 | -0.6228680793820724 | [48] | [33,22,38,29] | -8 | hSpCas9 | negative selection | 9148356 | 2262419 | 2262442 | 16 | - | 27260156 | TOV112D | viability | TTCCCTCTAGGATCACATCATGG | RNPS1 | ENSG00000205937 | -0.37965575042222216 | [755] | [523,907,449,521] | -6 | hSpCas9 | negative selection | 9205351 | 2262733 | 2262756 | 16 | + | 27260156 | TOV112D | viability | TCCTCACCTTTGTCACATTCCGG | RNPS1 | ENSG00000205937 | 0.25393120138400604 | [1973] | [2091,3560,2084,1972] | 5 | hSpCas9 | negative selection | 9205353 | 2263195 | 2263218 | 16 | - | 27260156 | TOV112D | viability | TCCTCAGCATCCAGCCGCTCAGG | RNPS1 | ENSG00000205937 | -0.5218660929442724 | [1046] | [715,1144,611,552] | -8 | hSpCas9 | negative selection | 9269605 | 2262739 | 2262762 | 16 | - | 27260156 | TOV112D | viability | ACTCACCCGGAATGTGACAAAGG | RNPS1 | ENSG00000205937 | -1.100254957260666 | [516] | [186,552,137,161] | -9 | hSpCas9 | negative selection | 9269606 | 2264191 | 2264214 | 16 | - | 27260156 | TOV112D | viability | AAGAGGCGCAGCGCTTCCAGTGG | RNPS1 | ENSG00000205937 | -0.8778549429346287 | [48] | [1,118,0,5] | -9 | hSpCas9 | negative selection | 9269607 | 2262419 | 2262442 | 16 | - | 27260156 | TC71 | viability | TTCCCTCTAGGATCACATCATGG | RNPS1 | ENSG00000205937 | -0.29490131145878407 | [755] | [596,799,508,747] | -7 | hSpCas9 | negative selection | 9326602 | 2262733 | 2262756 | 16 | + | 27260156 | TC71 | viability | TCCTCACCTTTGTCACATTCCGG | RNPS1 | ENSG00000205937 | 0.30722925664127576 | [1973] | [2778,2526,2410,2767] | 7 | hSpCas9 | negative selection | 9326604 | 2263195 | 2263218 | 16 | - | 27260156 | TC71 | viability | TCCTCAGCATCCAGCCGCTCAGG | RNPS1 | ENSG00000205937 | -0.6421345769677115 | [1046] | [814,715,640,703] | -9 | hSpCas9 | negative selection | 9390856 | 2262739 | 2262762 | 16 | - | 27260156 | TC71 | viability | ACTCACCCGGAATGTGACAAAGG | RNPS1 | ENSG00000205937 | -1.0380787880984523 | [516] | [348,274,210,242] | -9 | hSpCas9 | negative selection | 9390857 | 2264191 | 2264214 | 16 | - | 27260156 | TC71 | viability | AAGAGGCGCAGCGCTTCCAGTGG | RNPS1 | ENSG00000205937 | -0.6634637626104181 | [48] | [22,47,28,32] | -9 | hSpCas9 | negative selection | 9390858 | 2262419 | 2262442 | 16 | - | 27260156 | TC32 | viability | TTCCCTCTAGGATCACATCATGG | RNPS1 | ENSG00000205937 | -0.762577694275389 | [755] | [376,209,571,615] | -9 | hSpCas9 | negative selection | 9447853 | 2262733 | 2262756 | 16 | + | 27260156 | TC32 | viability | TCCTCACCTTTGTCACATTCCGG | RNPS1 | ENSG00000205937 | 0.30030724836340816 | [1973] | [2251,1896,2817,2269] | 5 | hSpCas9 | negative selection | 9447855 | 2263195 | 2263218 | 16 | - | 27260156 | TC32 | viability | TCCTCAGCATCCAGCCGCTCAGG | RNPS1 | ENSG00000205937 | -0.3285681571020006 | [1046] | [716,661,979,816] | -6 | hSpCas9 | negative selection | 9512107 | 2262739 | 2262762 | 16 | - | 27260156 | TC32 | viability | ACTCACCCGGAATGTGACAAAGG | RNPS1 | ENSG00000205937 | -1.2230274073754277 | [516] | [204,175,279,181] | -9 | hSpCas9 | negative selection | 9512108 | 2264191 | 2264214 | 16 | - | 27260156 | TC32 | viability | AAGAGGCGCAGCGCTTCCAGTGG | RNPS1 | ENSG00000205937 | -1.7200318493027722 | [48] | [7,0,41,14] | -9 | hSpCas9 | negative selection | 9512109 | 2263082 | 2263105 | 16 | + | 27869803 | HPAFII | viability after 27 days | CGCAGGGCACTCACTTGGAGCGG | RNPS1 | ENSG00000205937 | -1.5168072840371436 | [953] | [249,112,NaN] | -7 | hSpCas9 | negative selection | 9556216 | 2263082 | 2263105 | 16 | + | 27869803 | HPAFII | viability after 15 days | CGCAGGGCACTCACTTGGAGCGG | RNPS1 | ENSG00000205937 | -0.39122852146710096 | [953] | [938,683,NaN] | -4 | hSpCas9 | negative selection | 9638665 | 2263082 | 2263105 | 16 | + | 27869803 | ASPC1 | viability after 36 days | CGCAGGGCACTCACTTGGAGCGG | RNPS1 | ENSG00000205937 | 0.19794213081682321 | [2479] | [935,897,1097] | 2 | hSpCas9 | negative selection | 9721114 | 2263082 | 2263105 | 16 | + | 27869803 | PATU8988S | viability after 35 days | CGCAGGGCACTCACTTGGAGCGG | RNPS1 | ENSG00000205937 | -0.33180943510920846 | [2064] | [573,747,NaN] | -3 | hSpCas9 | negative selection | 9803563 | 2263082 | 2263105 | 16 | + | 27869803 | PATU8988S | viability after 31 days | CGCAGGGCACTCACTTGGAGCGG | RNPS1 | ENSG00000205937 | -0.13260683351260272 | [2064] | [630,903,NaN] | -1 | hSpCas9 | negative selection | 9886012 | 2263082 | 2263105 | 16 | + | 27869803 | HPAFII | viability after 35 days | CGCAGGGCACTCACTTGGAGCGG | RNPS1 | ENSG00000205937 | -1.272984567134436 | [953] | [252,139,NaN] | -6 | hSpCas9 | negative selection | 9968461 | 2263082 | 2263105 | 16 | + | 27869803 | HPAFII | viability after 31 days | CGCAGGGCACTCACTTGGAGCGG | RNPS1 | ENSG00000205937 | -1.5765768143760042 | [953] | [201,154,NaN] | -7 | hSpCas9 | negative selection | 10050910 | 2263083 | 2263106 | 16 | + | 28162770 | P31FUJ | viability | GCAGGGCACTCACTTGGAGCGGG | RNPS1 | ENSG00000205937 | -2.6856611691281898 | [218] | [39] | -9 | hSpCas9 | negative selection | 10226808 | 2264208 | 2264231 | 16 | - | 28162770 | P31FUJ | viability | GCCGGGACAAAACCCGAAAGAGG | RNPS1 | ENSG00000205937 | -2.3538176053757445 | [86] | [19] | -8 | hSpCas9 | negative selection | 10226809 | 2264560 | 2264583 | 16 | + | 28162770 | P31FUJ | viability | ACAGAAGGATTACCTAGTGCTGG | RNPS1 | ENSG00000205937 | 0.618054356279812 | [167] | [302] | 7 | hSpCas9 | negative selection | 10226810 | 2263194 | 2263217 | 16 | + | 28162770 | P31FUJ | viability | TCCTGAGCGGCTGGATGCTGAGG | RNPS1 | ENSG00000205937 | -1.4617747741745397 | [292] | [124] | -7 | hSpCas9 | negative selection | 10226811 | 2263083 | 2263106 | 16 | + | 28162770 | TF1 | viability | GCAGGGCACTCACTTGGAGCGGG | RNPS1 | ENSG00000205937 | NaN | [NaN] | [13] | 1 | hSpCas9 | negative selection | 10396174 | 2264208 | 2264231 | 16 | - | 28162770 | TF1 | viability | GCCGGGACAAAACCCGAAAGAGG | RNPS1 | ENSG00000205937 | NaN | [NaN] | [32] | 1 | hSpCas9 | negative selection | 10396175 | 2264560 | 2264583 | 16 | + | 28162770 | TF1 | viability | ACAGAAGGATTACCTAGTGCTGG | RNPS1 | ENSG00000205937 | NaN | [NaN] | [205] | 1 | hSpCas9 | negative selection | 10396176 | 2263194 | 2263217 | 16 | + | 28162770 | TF1 | viability | TCCTGAGCGGCTGGATGCTGAGG | RNPS1 | ENSG00000205937 | NaN | [NaN] | [68] | 1 | hSpCas9 | negative selection | 10396177 | 2263083 | 2263106 | 16 | + | 28162770 | SKM1 | viability | GCAGGGCACTCACTTGGAGCGGG | RNPS1 | ENSG00000205937 | -3.2814333166593026 | [54] | [9] | -9 | hSpCas9 | negative selection | 10565540 | 2264208 | 2264231 | 16 | - | 28162770 | SKM1 | viability | GCCGGGACAAAACCCGAAAGAGG | RNPS1 | ENSG00000205937 | -3.0443941193584534 | [27] | [5] | -9 | hSpCas9 | negative selection | 10565541 | 2264560 | 2264583 | 16 | + | 28162770 | SKM1 | viability | ACAGAAGGATTACCTAGTGCTGG | RNPS1 | ENSG00000205937 | -0.35111096400964414 | [56] | [78] | -3 | hSpCas9 | negative selection | 10565542 | 2263194 | 2263217 | 16 | + | 28162770 | SKM1 | viability | TCCTGAGCGGCTGGATGCTGAGG | RNPS1 | ENSG00000205937 | -1.9044638582139786 | [71] | [33] | -8 | hSpCas9 | negative selection | 10565543 | 2263083 | 2263106 | 16 | + | 28162770 | SKM1 | viability | GCAGGGCACTCACTTGGAGCGGG | RNPS1 | ENSG00000205937 | -3.2814333166593026 | [54] | [9] | -9 | hSpCas9 | negative selection | 10734906 | 2264208 | 2264231 | 16 | - | 28162770 | SKM1 | viability | GCCGGGACAAAACCCGAAAGAGG | RNPS1 | ENSG00000205937 | -3.0443941193584534 | [27] | [5] | -9 | hSpCas9 | negative selection | 10734907 | 2264560 | 2264583 | 16 | + | 28162770 | SKM1 | viability | ACAGAAGGATTACCTAGTGCTGG | RNPS1 | ENSG00000205937 | -0.35111096400964414 | [56] | [78] | -3 | hSpCas9 | negative selection | 10734908 | 2263194 | 2263217 | 16 | + | 28162770 | SKM1 | viability | TCCTGAGCGGCTGGATGCTGAGG | RNPS1 | ENSG00000205937 | -1.9044638582139786 | [71] | [33] | -8 | hSpCas9 | negative selection | 10734909 | 2263083 | 2263106 | 16 | + | 28162770 | PL21 | viability | GCAGGGCACTCACTTGGAGCGGG | RNPS1 | ENSG00000205937 | -1.8929697899021614 | [255] | [29] | -8 | hSpCas9 | negative selection | 10904272 | 2264208 | 2264231 | 16 | - | 28162770 | PL21 | viability | GCCGGGACAAAACCCGAAAGAGG | RNPS1 | ENSG00000205937 | -0.4358970708261054 | [114] | [36] | -3 | hSpCas9 | negative selection | 10904273 | 2264560 | 2264583 | 16 | + | 28162770 | PL21 | viability | ACAGAAGGATTACCTAGTGCTGG | RNPS1 | ENSG00000205937 | 0.43775142344320717 | [228] | [134] | 4 | hSpCas9 | negative selection | 10904274 | 2263194 | 2263217 | 16 | + | 28162770 | PL21 | viability | TCCTGAGCGGCTGGATGCTGAGG | RNPS1 | ENSG00000205937 | -0.011364490704391661 | [175] | [75] | 0 | hSpCas9 | negative selection | 10904275 | 2263083 | 2263106 | 16 | + | 28162770 | P31FUJ | viability | GCAGGGCACTCACTTGGAGCGGG | RNPS1 | ENSG00000205937 | -2.6856611691281898 | [218] | [39] | -9 | hSpCas9 | negative selection | 11073638 | 2264208 | 2264231 | 16 | - | 28162770 | P31FUJ | viability | GCCGGGACAAAACCCGAAAGAGG | RNPS1 | ENSG00000205937 | -2.3538176053757445 | [86] | [19] | -8 | hSpCas9 | negative selection | 11073639 | 2264560 | 2264583 | 16 | + | 28162770 | P31FUJ | viability | ACAGAAGGATTACCTAGTGCTGG | RNPS1 | ENSG00000205937 | 0.618054356279812 | [167] | [302] | 7 | hSpCas9 | negative selection | 11073640 | 2263194 | 2263217 | 16 | + | 28162770 | P31FUJ | viability | TCCTGAGCGGCTGGATGCTGAGG | RNPS1 | ENSG00000205937 | -1.4617747741745397 | [292] | [124] | -7 | hSpCas9 | negative selection | 11073641 | 2263083 | 2263106 | 16 | + | 28162770 | OCIAML5 | viability | GCAGGGCACTCACTTGGAGCGGG | RNPS1 | ENSG00000205937 | -2.2367304210993217 | [140] | [53] | -8 | hSpCas9 | negative selection | 11243004 | 2264208 | 2264231 | 16 | - | 28162770 | OCIAML5 | viability | GCCGGGACAAAACCCGAAAGAGG | RNPS1 | ENSG00000205937 | -2.20256381794813 | [50] | [19] | -8 | hSpCas9 | negative selection | 11243005 | 2264560 | 2264583 | 16 | + | 28162770 | OCIAML5 | viability | ACAGAAGGATTACCTAGTGCTGG | RNPS1 | ENSG00000205937 | 0.1249722806926919 | [94] | [186] | 1 | hSpCas9 | negative selection | 11243006 | 2263194 | 2263217 | 16 | + | 28162770 | OCIAML5 | viability | TCCTGAGCGGCTGGATGCTGAGG | RNPS1 | ENSG00000205937 | -0.828021096897346 | [118] | [120] | -5 | hSpCas9 | negative selection | 11243007 | 2263083 | 2263106 | 16 | + | 28162770 | EOL1 | viability | GCAGGGCACTCACTTGGAGCGGG | RNPS1 | ENSG00000205937 | -5.641506266600557 | [378] | [3] | -9 | hSpCas9 | negative selection | 11412370 | 2264208 | 2264231 | 16 | - | 28162770 | EOL1 | viability | GCCGGGACAAAACCCGAAAGAGG | RNPS1 | ENSG00000205937 | -0.9802949953891255 | [175] | [46] | -6 | hSpCas9 | negative selection | 11412371 | 2264560 | 2264583 | 16 | + | 28162770 | EOL1 | viability | ACAGAAGGATTACCTAGTGCTGG | RNPS1 | ENSG00000205937 | -0.1618125132326465 | [326] | [153] | -1 | hSpCas9 | negative selection | 11412372 | 2263194 | 2263217 | 16 | + | 28162770 | EOL1 | viability | TCCTGAGCGGCTGGATGCTGAGG | RNPS1 | ENSG00000205937 | -0.803019124593422 | [254] | [76] | -5 | hSpCas9 | negative selection | 11412373 | 2263083 | 2263106 | 16 | + | 28162770 | MOLM13 | viability | GCAGGGCACTCACTTGGAGCGGG | RNPS1 | ENSG00000205937 | -2.492582254268784 | [287] | [36] | -8 | hSpCas9 | negative selection | 11581736 | 2264208 | 2264231 | 16 | - | 28162770 | MOLM13 | viability | GCCGGGACAAAACCCGAAAGAGG | RNPS1 | ENSG00000205937 | -1.0024305532354547 | [132] | [47] | -5 | hSpCas9 | negative selection | 11581737 | 2264560 | 2264583 | 16 | + | 28162770 | MOLM13 | viability | ACAGAAGGATTACCTAGTGCTGG | RNPS1 | ENSG00000205937 | 0.47826852732457803 | [276] | [278] | 3 | hSpCas9 | negative selection | 11581738 | 2263194 | 2263217 | 16 | + | 28162770 | MOLM13 | viability | TCCTGAGCGGCTGGATGCTGAGG | RNPS1 | ENSG00000205937 | -1.1998135501845137 | [304] | [95] | -6 | hSpCas9 | negative selection | 11581739 | 2263083 | 2263106 | 16 | + | 28162770 | HEL | viability | GCAGGGCACTCACTTGGAGCGGG | RNPS1 | ENSG00000205937 | -2.2832605865558664 | [303] | [39] | -8 | hSpCas9 | negative selection | 11751102 | 2264208 | 2264231 | 16 | - | 28162770 | HEL | viability | GCCGGGACAAAACCCGAAAGAGG | RNPS1 | ENSG00000205937 | -2.0453171616849026 | [115] | [17] | -8 | hSpCas9 | negative selection | 11751103 | 2264560 | 2264583 | 16 | + | 28162770 | HEL | viability | ACAGAAGGATTACCTAGTGCTGG | RNPS1 | ENSG00000205937 | 0.542044832380884 | [266] | [248] | 4 | hSpCas9 | negative selection | 11751104 | 2263194 | 2263217 | 16 | + | 28162770 | HEL | viability | TCCTGAGCGGCTGGATGCTGAGG | RNPS1 | ENSG00000205937 | -1.357261167999643 | [203] | [50] | -7 | hSpCas9 | negative selection | 11751105 | 2263083 | 2263106 | 16 | + | 28162770 | MV411 | viability | GCAGGGCACTCACTTGGAGCGGG | RNPS1 | ENSG00000205937 | -1.4370606234892953 | [269] | [83] | -7 | hSpCas9 | negative selection | 11920468 | 2264208 | 2264231 | 16 | - | 28162770 | MV411 | viability | GCCGGGACAAAACCCGAAAGAGG | RNPS1 | ENSG00000205937 | -1.9318861486617867 | [76] | [16] | -8 | hSpCas9 | negative selection | 11920469 | 2264560 | 2264583 | 16 | + | 28162770 | MV411 | viability | ACAGAAGGATTACCTAGTGCTGG | RNPS1 | ENSG00000205937 | -0.47724971360499413 | [194] | [117] | -4 | hSpCas9 | negative selection | 11920470 | 2263194 | 2263217 | 16 | + | 28162770 | MV411 | viability | TCCTGAGCGGCTGGATGCTGAGG | RNPS1 | ENSG00000205937 | -1.5944976029849731 | [189] | [52] | -7 | hSpCas9 | negative selection | 11920471 | 2263083 | 2263106 | 16 | + | 28162770 | MONOMAC1 | viability | GCAGGGCACTCACTTGGAGCGGG | RNPS1 | ENSG00000205937 | -2.0568591890112935 | [97] | [26] | -9 | hSpCas9 | negative selection | 12089834 | 2264208 | 2264231 | 16 | - | 28162770 | MONOMAC1 | viability | GCCGGGACAAAACCCGAAAGAGG | RNPS1 | ENSG00000205937 | -0.9783965605842133 | [54] | [31] | -6 | hSpCas9 | negative selection | 12089835 | 2264560 | 2264583 | 16 | + | 28162770 | MONOMAC1 | viability | ACAGAAGGATTACCTAGTGCTGG | RNPS1 | ENSG00000205937 | 0.39714418369098103 | [103] | [156] | 4 | hSpCas9 | negative selection | 12089836 | 2263194 | 2263217 | 16 | + | 28162770 | MONOMAC1 | viability | TCCTGAGCGGCTGGATGCTGAGG | RNPS1 | ENSG00000205937 | 0.7540535524594999 | [119] | [231] | 7 | hSpCas9 | negative selection | 12089837 | 2263083 | 2263106 | 16 | + | 28162770 | OCIAML2 | viability | GCAGGGCACTCACTTGGAGCGGG | RNPS1 | ENSG00000205937 | -2.7530295559428866 | [44] | [36] | -9 | hSpCas9 | negative selection | 12259200 | 2264208 | 2264231 | 16 | - | 28162770 | OCIAML2 | viability | GCCGGGACAAAACCCGAAAGAGG | RNPS1 | ENSG00000205937 | -3.4706298252421615 | [25] | [12] | -9 | hSpCas9 | negative selection | 12259201 | 2264560 | 2264583 | 16 | + | 28162770 | OCIAML2 | viability | ACAGAAGGATTACCTAGTGCTGG | RNPS1 | ENSG00000205937 | 0.4387248103178383 | [38] | [292] | 4 | hSpCas9 | negative selection | 12259202 | 2263194 | 2263217 | 16 | + | 28162770 | OCIAML2 | viability | TCCTGAGCGGCTGGATGCTGAGG | RNPS1 | ENSG00000205937 | -3.544630406685938 | [39] | [18] | -9 | hSpCas9 | negative selection | 12259203 | 2263083 | 2263106 | 16 | + | 28162770 | OCIAML3 | viability | GCAGGGCACTCACTTGGAGCGGG | RNPS1 | ENSG00000205937 | -0.20794920801708527 | [43] | [114] | -2 | hSpCas9 | negative selection | 12428566 | 2264208 | 2264231 | 16 | - | 28162770 | OCIAML3 | viability | GCCGGGACAAAACCCGAAAGAGG | RNPS1 | ENSG00000205937 | -0.21961212554266518 | [26] | [69] | -2 | hSpCas9 | negative selection | 12428567 | 2264560 | 2264583 | 16 | + | 28162770 | OCIAML3 | viability | ACAGAAGGATTACCTAGTGCTGG | RNPS1 | ENSG00000205937 | 0.7610873184983984 | [42] | [219] | 6 | hSpCas9 | negative selection | 12428568 | 2263194 | 2263217 | 16 | + | 28162770 | OCIAML3 | viability | TCCTGAGCGGCTGGATGCTGAGG | RNPS1 | ENSG00000205937 | 1.0003535583992427 | [50] | [307] | 8 | hSpCas9 | negative selection | 12428569 |